C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 SMART SM00382 40 240 5.9E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 Gene3D G3DSA:3.40.50.300 9 338 1.5E-99 T 15-10-2018 C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 307 7.3E-19 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 Pfam PF00005 ABC transporter 32 190 1.4E-27 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 SUPERFAMILY SSF52540 40 312 2.72E-69 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11660 d23f5e882d08b80080b88f4064fc154d 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 326 6.8E-27 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.2E-7 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 343 1.2E-7 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 SUPERFAMILY SSF51905 5 381 1.69E-49 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 Gene3D G3DSA:3.50.50.60 2 249 3.5E-45 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PIRSF PIRSF000171 282 513 1.7E-10 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PIRSF PIRSF000171 3 222 8.1E-22 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 SUPERFAMILY SSF46977 408 504 8.37E-21 T 15-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 Pfam PF02910 Fumarate reductase flavoprotein C-term 429 498 8.8E-10 T 15-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 Pfam PF00890 FAD binding domain 10 215 2.7E-21 T 15-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 8.2E-16 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 8.2E-16 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 321 343 8.2E-16 T 15-10-2018 C2I28_24515 7410351bfdeb7a88a8121e6df374808f 532 Gene3D G3DSA:1.20.58.100 388 497 1.8E-16 T 15-10-2018 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Gene3D G3DSA:3.40.50.720 1 206 8.3E-65 T 15-10-2018 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 203 9.9E-43 T 15-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 SUPERFAMILY SSF48179 355 447 1.28E-17 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 362 411 2.6E-6 T 15-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 206 303 3.8E-9 T 15-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Pfam PF00378 Enoyl-CoA hydratase/isomerase 488 620 4.8E-11 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Gene3D G3DSA:1.10.1040.10 357 469 9.5E-9 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Gene3D G3DSA:1.10.1040.10 207 332 3.5E-17 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 SUPERFAMILY SSF51735 1 204 4.07E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06595 708e405d1496386cf29d69d9710cc950 792 SUPERFAMILY SSF52096 480 789 5.91E-38 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_06595 708e405d1496386cf29d69d9710cc950 792 SUPERFAMILY SSF48179 204 324 1.62E-20 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_06595 708e405d1496386cf29d69d9710cc950 792 Gene3D G3DSA:3.90.226.10 483 684 4.4E-27 T 15-10-2018 C2I28_01480 6f9513a87faf89d41bec44f83e2d0c63 160 SUPERFAMILY SSF55729 4 153 9.03E-24 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01480 6f9513a87faf89d41bec44f83e2d0c63 160 Gene3D G3DSA:3.40.630.30 1 138 3.2E-21 T 15-10-2018 C2I28_01480 6f9513a87faf89d41bec44f83e2d0c63 160 Pfam PF00583 Acetyltransferase (GNAT) family 35 129 9.2E-13 T 15-10-2018 IPR000182 GNAT domain C2I28_24625 2b113bbb775011c42fa62028833ffba3 75 Pfam PF01206 Sulfurtransferase TusA 6 74 4.8E-25 T 15-10-2018 IPR001455 TusA-like domain C2I28_24625 2b113bbb775011c42fa62028833ffba3 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 15-10-2018 IPR001455 TusA-like domain C2I28_24625 2b113bbb775011c42fa62028833ffba3 75 SUPERFAMILY SSF64307 2 74 4.84E-26 T 15-10-2018 IPR036868 TusA-like domain superfamily C2I28_24625 2b113bbb775011c42fa62028833ffba3 75 Gene3D G3DSA:3.30.110.40 1 75 5.5E-31 T 15-10-2018 IPR036868 TusA-like domain superfamily C2I28_02355 f15fec80bc40d245d6f1138646006b4d 419 SUPERFAMILY SSF50156 173 267 1.13E-18 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_02355 f15fec80bc40d245d6f1138646006b4d 419 Gene3D G3DSA:2.30.42.10 200 288 6.6E-21 T 15-10-2018 C2I28_02355 f15fec80bc40d245d6f1138646006b4d 419 Pfam PF13180 PDZ domain 206 265 3.2E-8 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_02355 f15fec80bc40d245d6f1138646006b4d 419 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 418 3.3E-115 T 15-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 C2I28_02355 f15fec80bc40d245d6f1138646006b4d 419 Pfam PF02163 Peptidase family M50 6 405 6.5E-81 T 15-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 C2I28_02355 f15fec80bc40d245d6f1138646006b4d 419 SMART SM00228 189 258 2.2E-6 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_09360 c08778912d2fb6922efdb88f817dba68 730 Pfam PF01841 Transglutaminase-like superfamily 425 548 6.6E-27 T 15-10-2018 IPR002931 Transglutaminase-like C2I28_09360 c08778912d2fb6922efdb88f817dba68 730 SUPERFAMILY SSF54001 405 662 5.05E-44 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_09360 c08778912d2fb6922efdb88f817dba68 730 Gene3D G3DSA:3.10.620.30 384 563 1.3E-23 T 15-10-2018 C2I28_09360 c08778912d2fb6922efdb88f817dba68 730 SMART SM00460 474 550 6.9E-21 T 15-10-2018 IPR002931 Transglutaminase-like C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 15-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 SUPERFAMILY SSF53335 145 362 1.6E-36 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 Gene3D G3DSA:3.40.50.150 162 367 6.0E-122 T 15-10-2018 C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 Pfam PF01170 Putative RNA methylase family UPF0020 164 368 1.1E-59 T 15-10-2018 IPR000241 Putative RNA methylase domain C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 Gene3D G3DSA:3.30.2130.30 8 247 6.0E-122 T 15-10-2018 C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 SMART SM00981 57 156 1.5E-5 T 15-10-2018 IPR004114 THUMP domain GO:0003723 C2I28_15225 d35de2d66b9f1acba157282c85d82ec8 381 Pfam PF02926 THUMP domain 19 122 7.6E-11 T 15-10-2018 IPR004114 THUMP domain GO:0003723 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 SUPERFAMILY SSF46689 6 55 3.05E-8 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 SMART SM00871 128 288 3.2E-38 T 15-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 Gene3D G3DSA:1.10.10.60 4 57 3.9E-14 T 15-10-2018 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 SMART SM00342 21 104 8.6E-27 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 Pfam PF06445 GyrI-like small molecule binding domain 128 287 2.4E-29 T 15-10-2018 IPR029442 GyrI-like small molecule binding domain C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 Gene3D G3DSA:1.10.10.60 58 116 2.9E-13 T 15-10-2018 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 SUPERFAMILY SSF46689 57 110 1.93E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 SUPERFAMILY SSF55136 128 290 4.45E-32 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 Pfam PF12833 Helix-turn-helix domain 28 105 2.1E-16 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 Gene3D G3DSA:3.20.80.10 128 290 7.8E-40 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_00520 fd6ac403987c630f2346fd71a7405b49 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 Pfam PF01264 Chorismate synthase 1 362 2.9E-124 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 Gene3D G3DSA:3.60.150.10 1 388 8.9E-155 T 15-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 SUPERFAMILY SSF103263 1 387 3.27E-149 T 15-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 367 1.4E-131 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 36.711 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 15-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 15-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 15-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_23135 7af65ab01473357520d5f903dc684c15 388 PIRSF PIRSF001456 1 385 6.7E-130 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_04095 b0c13567710442445123b90f02f78c2c 759 SUPERFAMILY SSF51161 243 340 1.0E-16 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_04095 b0c13567710442445123b90f02f78c2c 759 Gene3D G3DSA:3.30.310.50 678 759 1.4E-8 T 15-10-2018 C2I28_04095 b0c13567710442445123b90f02f78c2c 759 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 260 292 1.1E-6 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_04095 b0c13567710442445123b90f02f78c2c 759 SUPERFAMILY SSF53448 2 272 9.15E-79 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_04095 b0c13567710442445123b90f02f78c2c 759 SUPERFAMILY SSF55957 681 755 4.45E-9 T 15-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_04095 b0c13567710442445123b90f02f78c2c 759 Pfam PF00483 Nucleotidyl transferase 2 231 1.7E-52 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_04095 b0c13567710442445123b90f02f78c2c 759 Gene3D G3DSA:2.160.10.10 237 360 6.3E-16 T 15-10-2018 C2I28_04095 b0c13567710442445123b90f02f78c2c 759 Gene3D G3DSA:3.90.550.10 1 235 1.9E-74 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Hamap MF_01113 DNA polymerase IV [dinB]. 9 361 34.846 T 15-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 SUPERFAMILY SSF100879 249 345 7.53E-23 T 15-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Pfam PF00817 impB/mucB/samB family 15 162 4.0E-45 T 15-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Gene3D G3DSA:3.30.1490.100 251 358 3.7E-23 T 15-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 350 2.5E-18 T 15-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Pfam PF11798 IMS family HHH motif 176 204 1.6E-6 T 15-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Gene3D G3DSA:1.10.150.20 176 243 4.9E-15 T 15-10-2018 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Gene3D G3DSA:3.30.70.270 12 172 8.8E-53 T 15-10-2018 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 Gene3D G3DSA:2.30.40.20 29 82 8.8E-53 T 15-10-2018 C2I28_19445 afb28cf23dbea3a5bc99f4d995f5e237 402 SUPERFAMILY SSF56672 9 242 1.87E-73 T 15-10-2018 C2I28_09595 3d227273ad297a1ff035332538933a61 354 Pfam PF10282 Lactonase, 7-bladed beta-propeller 10 350 1.7E-121 T 15-10-2018 IPR019405 Lactonase, 7-bladed beta propeller C2I28_09595 3d227273ad297a1ff035332538933a61 354 SUPERFAMILY SSF51004 16 352 1.14E-49 T 15-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily C2I28_09595 3d227273ad297a1ff035332538933a61 354 Gene3D G3DSA:2.130.10.10 8 354 6.3E-116 T 15-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I28_17070 45db60aabac15b3b3294622b5b4ed602 317 Gene3D G3DSA:1.10.3720.10 85 308 7.8E-23 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_17070 45db60aabac15b3b3294622b5b4ed602 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 4.1E-42 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_17070 45db60aabac15b3b3294622b5b4ed602 317 SUPERFAMILY SSF161098 90 297 7.2E-18 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 15-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.285 T 15-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 SMART SM00072 4 187 4.0E-74 T 15-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 SUPERFAMILY SSF52540 4 190 2.15E-69 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 Gene3D G3DSA:3.40.50.300 9 183 4.6E-68 T 15-10-2018 C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 Gene3D G3DSA:3.30.63.10 37 96 4.6E-68 T 15-10-2018 C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 2.7E-73 T 15-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 C2I28_02790 e277bf4dab3e8b4881e4d99e88d2cbd2 204 Pfam PF00625 Guanylate kinase 7 185 2.2E-52 T 15-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit C2I28_08975 007e91aee0d926e27f291178b63ebf44 201 Pfam PF04519 Polymer-forming cytoskeletal 125 178 1.3E-6 T 15-10-2018 IPR007607 Bactofilin A/B C2I28_08975 007e91aee0d926e27f291178b63ebf44 201 Pfam PF13490 Putative zinc-finger 8 38 8.3E-5 T 15-10-2018 IPR027383 Putative zinc-finger C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 373 2.7E-132 T 15-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 Pfam PF02926 THUMP domain 44 162 5.3E-19 T 15-10-2018 IPR004114 THUMP domain GO:0003723 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 Gene3D G3DSA:3.40.50.620 175 403 2.0E-77 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 6.5E-67 T 15-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 SMART SM00981 74 165 7.3E-22 T 15-10-2018 IPR004114 THUMP domain GO:0003723 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 403 161.363 T 15-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 Gene3D G3DSA:3.30.2130.30 1 174 2.6E-60 T 15-10-2018 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 SUPERFAMILY SSF52402 174 383 1.94E-51 T 15-10-2018 C2I28_05565 0297fe9a650530bb3d114108a0d8b622 403 SUPERFAMILY SSF143437 3 173 6.1E-53 T 15-10-2018 C2I28_25700 514296874849504b8d15ef52c7f787db 223 SUPERFAMILY SSF50800 7 216 1.26E-64 T 15-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I28_25700 514296874849504b8d15ef52c7f787db 223 Gene3D G3DSA:2.40.33.20 2 222 3.1E-67 T 15-10-2018 C2I28_25700 514296874849504b8d15ef52c7f787db 223 Pfam PF03475 3-alpha domain 174 216 2.5E-12 T 15-10-2018 IPR005163 3-alpha domain C2I28_25700 514296874849504b8d15ef52c7f787db 223 Pfam PF03473 MOSC domain 55 164 6.5E-22 T 15-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 C2I28_03910 a530cf10f9e387ff74adb47731333dc8 315 SUPERFAMILY SSF52540 17 267 9.06E-22 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03910 a530cf10f9e387ff74adb47731333dc8 315 SMART SM00382 136 285 5.1E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_03910 a530cf10f9e387ff74adb47731333dc8 315 Gene3D G3DSA:3.40.50.300 118 282 3.5E-25 T 15-10-2018 C2I28_03910 a530cf10f9e387ff74adb47731333dc8 315 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 29 295 1.0E-120 T 15-10-2018 IPR014217 Sporulation stage III, protein AA C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 SUPERFAMILY SSF52374 163 374 1.27E-88 T 15-10-2018 C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 Gene3D G3DSA:3.10.400.10 21 159 8.5E-47 T 15-10-2018 C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 25 373 4.7E-136 T 15-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 SUPERFAMILY SSF88697 4 156 1.29E-48 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 Pfam PF01747 ATP-sulfurylase 163 373 1.8E-96 T 15-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 21 377 51.003 T 15-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 Gene3D G3DSA:3.40.50.620 164 375 1.7E-98 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_06200 88867c401dffc7c4188ce5c53b1ef6bf 383 Pfam PF14306 PUA-like domain 5 154 3.6E-50 T 15-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I28_18440 6be1a662b068bd55d017571cfa29842b 331 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 325 1.7E-109 T 15-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_18440 6be1a662b068bd55d017571cfa29842b 331 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 325 64.285 T 15-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_18440 6be1a662b068bd55d017571cfa29842b 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 187 9.4E-31 T 15-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_18440 6be1a662b068bd55d017571cfa29842b 331 Gene3D G3DSA:3.40.47.10 1 331 2.3E-116 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_18440 6be1a662b068bd55d017571cfa29842b 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 325 4.2E-28 T 15-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_18440 6be1a662b068bd55d017571cfa29842b 331 SUPERFAMILY SSF53901 4 325 2.24E-64 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_09985 dbb69cbb6eb9e67d33440fc7ca350890 137 SUPERFAMILY SSF50475 4 133 9.35E-29 T 15-10-2018 C2I28_09985 dbb69cbb6eb9e67d33440fc7ca350890 137 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 6 133 6.0E-16 T 15-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain C2I28_09985 dbb69cbb6eb9e67d33440fc7ca350890 137 Gene3D G3DSA:2.30.110.10 3 136 8.8E-37 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PIRSF PIRSF001369 1 366 2.6E-126 T 15-10-2018 IPR024176 Citrate synthase, bacterial-type C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 Gene3D G3DSA:1.10.230.10 216 318 4.4E-124 T 15-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PRINTS PR00143 Citrate synthase signature 190 218 1.2E-33 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PRINTS PR00143 Citrate synthase signature 168 183 1.2E-33 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PRINTS PR00143 Citrate synthase signature 304 320 1.2E-33 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PRINTS PR00143 Citrate synthase signature 324 338 1.2E-33 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PRINTS PR00143 Citrate synthase signature 243 263 1.2E-33 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 PRINTS PR00143 Citrate synthase signature 119 132 1.2E-33 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 SUPERFAMILY SSF48256 2 362 8.24E-120 T 15-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 1.1E-116 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 Gene3D G3DSA:1.10.580.10 17 344 4.4E-124 T 15-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I28_23395 7107f19ba9a83a8a14523f7daf91966c 367 ProSitePatterns PS00480 Citrate synthase signature. 250 262 - T 15-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I28_04085 1d3ad202500e739fcb55c00ee3865e77 188 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 179 1.3E-56 T 15-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase C2I28_04085 1d3ad202500e739fcb55c00ee3865e77 188 SUPERFAMILY SSF100950 2 185 4.05E-53 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_04085 1d3ad202500e739fcb55c00ee3865e77 188 PIRSF PIRSF006806 1 182 1.8E-50 T 15-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase C2I28_04085 1d3ad202500e739fcb55c00ee3865e77 188 Gene3D G3DSA:3.40.50.10420 1 188 2.3E-64 T 15-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily C2I28_04085 1d3ad202500e739fcb55c00ee3865e77 188 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 179 1.2E-47 T 15-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 Pfam PF00107 Zinc-binding dehydrogenase 153 263 5.1E-26 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 SUPERFAMILY SSF51735 113 268 2.6E-45 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 Gene3D G3DSA:3.90.180.10 10 322 2.7E-90 T 15-10-2018 C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 Gene3D G3DSA:3.40.50.720 125 269 2.7E-90 T 15-10-2018 C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.7E-11 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 SMART SM00829 10 323 2.0E-48 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 15-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 C2I28_12695 04404fa1695d9e4f3880f4b94c38813f 327 SUPERFAMILY SSF50129 1 146 1.67E-38 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 SUPERFAMILY SSF46894 127 222 1.48E-26 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 222 1.3E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 SMART SM00448 1 113 3.5E-40 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 SUPERFAMILY SSF52172 1 121 5.12E-37 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 SMART SM00862 146 222 2.8E-22 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 Gene3D G3DSA:3.40.50.2300 1 122 9.2E-37 T 15-10-2018 C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 Gene3D G3DSA:1.10.10.10 123 224 1.8E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18075 ef77461d519d3a270ab88508b30a63bb 224 Pfam PF00072 Response regulator receiver domain 3 113 4.6E-28 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03360 9d2c101f5eae4c9771f4f978cc0c23a3 151 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 78 148 8.0E-14 T 15-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane C2I28_03360 9d2c101f5eae4c9771f4f978cc0c23a3 151 Pfam PF10864 Protein of unknown function (DUF2663) 18 149 1.6E-36 T 15-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane C2I28_20410 801bba265cce5bd606805335d8aa7b16 445 Pfam PF00877 NlpC/P60 family 332 440 2.5E-24 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_20410 801bba265cce5bd606805335d8aa7b16 445 SUPERFAMILY SSF54001 310 440 1.96E-29 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_20410 801bba265cce5bd606805335d8aa7b16 445 Gene3D G3DSA:3.90.1720.10 239 444 8.8E-42 T 15-10-2018 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 Pfam PF00390 Malic enzyme, N-terminal domain 82 263 2.3E-68 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 SMART SM01274 82 264 2.1E-83 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 Gene3D G3DSA:3.40.50.720 272 566 1.2E-109 T 15-10-2018 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 Pfam PF03949 Malic enzyme, NAD binding domain 274 533 6.4E-105 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 Gene3D G3DSA:3.40.50.10380 16 271 2.3E-100 T 15-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 SUPERFAMILY SSF53223 6 273 1.58E-97 T 15-10-2018 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PIRSF PIRSF000106 2 565 7.0E-224 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 270 286 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 186 208 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 150 179 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 301 317 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 412 428 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 88 112 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 PRINTS PR00072 Malic enzyme signature 245 263 9.6E-67 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 ProSitePatterns PS00331 Malic enzymes signature. 270 286 - T 15-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 SMART SM00919 274 534 1.1E-123 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_21280 57a02fb879af78c030895dc7f2ee7f50 567 SUPERFAMILY SSF51735 274 563 4.38E-92 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19825 7ac25635b860cec9730866bb518df755 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 130 2.2E-17 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_19825 7ac25635b860cec9730866bb518df755 414 Gene3D G3DSA:2.40.110.10 133 247 3.4E-49 T 15-10-2018 C2I28_19825 7ac25635b860cec9730866bb518df755 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 229 7.9E-20 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_19825 7ac25635b860cec9730866bb518df755 414 Gene3D G3DSA:1.20.140.10 248 408 1.4E-39 T 15-10-2018 C2I28_19825 7ac25635b860cec9730866bb518df755 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 395 3.4E-35 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_19825 7ac25635b860cec9730866bb518df755 414 Gene3D G3DSA:1.10.540.10 1 132 9.2E-56 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_19825 7ac25635b860cec9730866bb518df755 414 SUPERFAMILY SSF56645 3 260 1.44E-71 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_19825 7ac25635b860cec9730866bb518df755 414 SUPERFAMILY SSF47203 245 402 1.06E-44 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 1.1E-38 T 15-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 SUPERFAMILY SSF55979 254 377 8.17E-31 T 15-10-2018 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 SUPERFAMILY SSF55979 1 127 5.18E-24 T 15-10-2018 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 Gene3D G3DSA:3.10.150.10 1 250 6.7E-137 T 15-10-2018 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 1.1E-125 T 15-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 1.4E-39 T 15-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 1.0E-35 T 15-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 PIRSF PIRSF000804 1 378 1.6E-116 T 15-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 SUPERFAMILY SSF55979 133 251 1.24E-27 T 15-10-2018 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 Gene3D G3DSA:3.70.10.10 145 375 6.7E-137 T 15-10-2018 C2I28_08020 3b9aa93aebde4a4042fe24cfcdae12ab 378 SMART SM00480 17 373 1.3E-168 T 15-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 C2I28_08710 4fd86464fe164a1fe0a342e2a20cb389 113 Gene3D G3DSA:3.90.470.10 1 113 1.2E-50 T 15-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08710 4fd86464fe164a1fe0a342e2a20cb389 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 7.0E-52 T 15-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08710 4fd86464fe164a1fe0a342e2a20cb389 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.247 T 15-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08710 4fd86464fe164a1fe0a342e2a20cb389 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 15-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08710 4fd86464fe164a1fe0a342e2a20cb389 113 SUPERFAMILY SSF54843 1 112 4.97E-44 T 15-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08710 4fd86464fe164a1fe0a342e2a20cb389 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 4.1E-37 T 15-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 C2I28_00350 249f4925bd0545e77de8587c20a8761a 264 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 53 262 5.9E-35 T 15-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I28_00350 249f4925bd0545e77de8587c20a8761a 264 Pfam PF04085 rod shape-determining protein MreC 108 259 1.3E-37 T 15-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I28_00350 249f4925bd0545e77de8587c20a8761a 264 Gene3D G3DSA:2.40.10.350 159 248 7.0E-44 T 15-10-2018 C2I28_00350 249f4925bd0545e77de8587c20a8761a 264 Gene3D G3DSA:2.40.10.340 105 255 7.0E-44 T 15-10-2018 C2I28_00350 249f4925bd0545e77de8587c20a8761a 264 PIRSF PIRSF038471 38 264 4.4E-45 T 15-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SMART SM00838 527 616 4.5E-5 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SUPERFAMILY SSF50447 219 336 4.82E-15 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SMART SM00889 411 525 1.5E-20 T 15-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR00315 GTP-binding elongation factor signature 7 20 7.7E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR00315 GTP-binding elongation factor signature 53 61 7.7E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR00315 GTP-binding elongation factor signature 73 83 7.7E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR00315 GTP-binding elongation factor signature 125 134 7.7E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR00315 GTP-binding elongation factor signature 89 100 7.7E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SUPERFAMILY SSF52540 6 229 3.25E-65 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 208 230 9.3E-14 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 111 134 9.3E-14 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 261 287 9.3E-14 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SUPERFAMILY SSF54980 338 412 7.19E-12 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Pfam PF00009 Elongation factor Tu GTP binding domain 7 232 3.1E-54 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Gene3D G3DSA:3.40.50.300 3 241 1.0E-67 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Gene3D G3DSA:3.30.70.240 531 601 9.2E-40 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Pfam PF03764 Elongation factor G, domain IV 410 525 5.1E-20 T 15-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 159 7.6E-22 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Pfam PF14492 Elongation Factor G, domain II 359 408 8.7E-8 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Gene3D G3DSA:3.30.70.870 345 414 4.2E-10 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Gene3D G3DSA:2.40.30.10 242 338 4.0E-15 T 15-10-2018 C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Gene3D G3DSA:3.30.230.10 432 609 9.2E-40 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 Pfam PF00679 Elongation factor G C-terminus 528 609 2.0E-17 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SUPERFAMILY SSF54980 528 609 4.32E-15 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_20340 20d7e532d2823b8320d09f7183f3158a 653 SUPERFAMILY SSF54211 410 525 3.45E-26 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_11760 c95f8c0f093561e31abef62d8887fbbe 221 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 181 8.2E-68 T 15-10-2018 IPR022301 Integral membrane protein YjbE C2I28_11760 c95f8c0f093561e31abef62d8887fbbe 221 Pfam PF03741 Integral membrane protein TerC family 12 180 2.5E-43 T 15-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 SUPERFAMILY SSF48452 8 188 4.05E-21 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 SMART SM00028 27 60 10.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 SMART SM00028 125 158 0.06 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 SMART SM00028 161 191 24.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 Gene3D G3DSA:1.25.40.10 106 318 4.5E-23 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 SUPERFAMILY SSF48452 160 255 1.61E-10 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 Pfam PF13181 Tetratricopeptide repeat 127 156 0.0083 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26600 8ed830501a6ccbfb31ebf5575735691a 368 Gene3D G3DSA:1.25.40.10 6 70 4.0E-8 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 Gene3D G3DSA:1.10.8.60 317 386 2.2E-23 T 15-10-2018 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 SUPERFAMILY SSF46689 408 457 5.38E-9 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 SMART SM00382 164 312 4.6E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 Pfam PF00158 Sigma-54 interaction domain 145 312 2.3E-66 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 117 4.2E-8 T 15-10-2018 IPR000014 PAS domain C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 Gene3D G3DSA:3.40.50.300 128 316 9.6E-67 T 15-10-2018 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 Pfam PF13426 PAS domain 15 111 8.2E-8 T 15-10-2018 IPR000014 PAS domain C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 Gene3D G3DSA:1.10.10.60 387 458 2.2E-7 T 15-10-2018 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 SUPERFAMILY SSF55785 3 110 3.53E-11 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 SUPERFAMILY SSF52540 143 386 1.0E-67 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 Gene3D G3DSA:3.30.450.20 2 118 2.6E-14 T 15-10-2018 C2I28_19360 4dc23c6a9fe7f59980682378ad843938 458 SMART SM00091 4 71 6.1E-7 T 15-10-2018 IPR000014 PAS domain C2I28_10480 21d1e22ebe4d4cc9f1e965975d868a05 107 Pfam PF12986 Domain of unknown function (DUF3870) 8 99 6.1E-31 T 15-10-2018 IPR024617 Domain of unknown function DUF3870 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 SUPERFAMILY SSF52768 6 373 7.67E-106 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 1.4E-17 T 15-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 1.4E-17 T 15-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 1.4E-17 T 15-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 Pfam PF00850 Histone deacetylase domain 22 314 2.4E-76 T 15-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 Gene3D G3DSA:3.40.800.20 3 372 6.4E-99 T 15-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 333 349 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 350 369 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_05625 3963e8aaa588b0f7861f9f9d09b92ee9 387 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 1.4E-40 T 15-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 314 1.0E-21 T 15-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 282 2.1E-40 T 15-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 Gene3D G3DSA:3.40.50.720 35 311 5.6E-75 T 15-10-2018 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 Gene3D G3DSA:3.30.70.260 316 399 4.5E-18 T 15-10-2018 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 SUPERFAMILY SSF52283 33 112 1.19E-21 T 15-10-2018 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 15-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 Gene3D G3DSA:3.40.50.720 92 286 5.6E-75 T 15-10-2018 C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 SUPERFAMILY SSF51735 94 283 6.63E-41 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_20130 da9ea4c16ee73f4d1fcbd90a30f26158 399 SUPERFAMILY SSF55021 317 394 4.58E-13 T 15-10-2018 C2I28_24450 da293c70fefad40eaf1b21185c1f84dd 406 Pfam PF07690 Major Facilitator Superfamily 18 360 4.5E-40 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_24450 da293c70fefad40eaf1b21185c1f84dd 406 Gene3D G3DSA:1.20.1250.20 205 398 1.3E-19 T 15-10-2018 C2I28_24450 da293c70fefad40eaf1b21185c1f84dd 406 SUPERFAMILY SSF103473 6 391 1.28E-58 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_24450 da293c70fefad40eaf1b21185c1f84dd 406 Gene3D G3DSA:1.20.1250.20 2 198 3.3E-31 T 15-10-2018 C2I28_25390 89575396358469944ad7f503fa42b98c 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 181 209 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_25390 89575396358469944ad7f503fa42b98c 289 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 284 1.1E-58 T 15-10-2018 C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 182 1.1E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 1.1E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 133 1.1E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 1.9E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 1.9E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 1.9E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 1.9E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 1.9E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25390 89575396358469944ad7f503fa42b98c 289 Gene3D G3DSA:3.40.50.720 2 287 1.9E-87 T 15-10-2018 C2I28_25390 89575396358469944ad7f503fa42b98c 289 SUPERFAMILY SSF51735 44 285 1.36E-79 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 Gene3D G3DSA:1.20.1480.50 144 240 1.9E-14 T 15-10-2018 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 Pfam PF00672 HAMP domain 184 231 3.7E-11 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 Gene3D G3DSA:3.30.565.10 305 457 8.0E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 SUPERFAMILY SSF47384 220 301 1.14E-16 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 SUPERFAMILY SSF55874 291 454 5.37E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 Gene3D G3DSA:1.10.287.130 241 302 1.6E-12 T 15-10-2018 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 3.0E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 3.0E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 3.0E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 3.0E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 456 4.4E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 SMART SM00388 235 301 1.1E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 300 4.7E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 SUPERFAMILY SSF158472 183 232 3.79E-9 T 15-10-2018 C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 SMART SM00387 346 458 3.9E-38 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_17490 5fead8a0ab3ad7fe6a1e0145d69a17ea 458 SMART SM00304 182 234 4.3E-8 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.464 T 15-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 PIRSF PIRSF002134 1 121 3.6E-41 T 15-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.6E-32 T 15-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 Gene3D G3DSA:4.10.910.10 72 121 2.5E-24 T 15-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 15-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 SUPERFAMILY SSF46946 2 114 1.28E-44 T 15-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.9E-52 T 15-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08810 145a7134f9c9f1012374ac26109d7785 121 Gene3D G3DSA:1.10.8.50 1 71 7.0E-29 T 15-10-2018 C2I28_25970 02af5439883c2c266b664490f2be5aa8 273 SUPERFAMILY SSF55136 147 270 1.75E-13 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_25970 02af5439883c2c266b664490f2be5aa8 273 SMART SM00422 9 78 6.9E-23 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_25970 02af5439883c2c266b664490f2be5aa8 273 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_25970 02af5439883c2c266b664490f2be5aa8 273 Gene3D G3DSA:1.10.1660.10 7 151 1.3E-27 T 15-10-2018 C2I28_25970 02af5439883c2c266b664490f2be5aa8 273 SUPERFAMILY SSF46955 9 120 4.03E-24 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_25970 02af5439883c2c266b664490f2be5aa8 273 Pfam PF13411 MerR HTH family regulatory protein 9 76 1.3E-14 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 SUPERFAMILY SSF56601 341 671 8.91E-85 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 SUPERFAMILY SSF54427 30 145 6.35E-27 T 15-10-2018 IPR032710 NTF2-like domain superfamily C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Gene3D G3DSA:3.40.710.10 339 672 2.1E-92 T 15-10-2018 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 SUPERFAMILY SSF56519 149 339 3.79E-35 T 15-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Gene3D G3DSA:3.90.1310.10 156 334 1.0E-47 T 15-10-2018 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Gene3D G3DSA:3.30.1390.30 176 250 1.0E-47 T 15-10-2018 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Gene3D G3DSA:3.10.450.100 26 143 1.7E-17 T 15-10-2018 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Pfam PF03717 Penicillin-binding Protein dimerisation domain 156 325 1.3E-33 T 15-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Pfam PF00905 Penicillin binding protein transpeptidase domain 357 667 2.1E-71 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_05105 b28c48f36249ab9911b68c2558e01a2d 672 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 28 147 2.9E-29 T 15-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Gene3D G3DSA:1.20.1440.210 50 175 5.8E-30 T 15-10-2018 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 728 741 6.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 687 697 6.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 669 683 6.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 PRINTS PR00344 Bacterial sensor protein C-terminal signature 704 722 6.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Gene3D G3DSA:1.20.1480.50 176 269 1.7E-5 T 15-10-2018 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Pfam PF00072 Response regulator receiver domain 799 909 4.1E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Pfam PF00512 His Kinase A (phospho-acceptor) domain 505 572 1.7E-20 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Gene3D G3DSA:3.40.50.12740 796 916 3.7E-44 T 15-10-2018 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SMART SM00065 283 436 4.3E-5 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SUPERFAMILY SSF47384 491 573 1.31E-21 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SMART SM00304 212 266 0.008 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Gene3D G3DSA:3.30.450.40 270 422 3.5E-15 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SUPERFAMILY SSF55874 561 745 3.54E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SMART SM00387 619 744 4.0E-38 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SUPERFAMILY SSF52172 794 914 1.85E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SMART SM00388 504 572 6.6E-24 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SMART SM00448 797 911 8.5E-40 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Gene3D G3DSA:1.10.287.130 466 570 1.2E-25 T 15-10-2018 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 619 741 5.5E-31 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Gene3D G3DSA:3.30.565.10 571 745 1.5E-49 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Pfam PF13185 GAF domain 282 419 5.0E-15 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 Pfam PF05227 CHASE3 domain 46 179 9.9E-34 T 15-10-2018 IPR007891 CHASE3 C2I28_15730 c1d3e0418f97e4e20fdc09dd8c6be774 917 SUPERFAMILY SSF55781 257 419 1.18E-21 T 15-10-2018 C2I28_05830 13a1ac39338a24251f4f6bf8d1d4343f 352 Pfam PF10776 Protein of unknown function (DUF2600) 20 348 1.4E-148 T 15-10-2018 IPR019712 Protein of unknown function DUF2600 C2I28_09780 d3110df3376da5a98c5c4d962fa8a687 219 Gene3D G3DSA:3.40.50.280 86 213 5.7E-23 T 15-10-2018 C2I28_09780 d3110df3376da5a98c5c4d962fa8a687 219 Pfam PF02310 B12 binding domain 92 184 3.1E-15 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_09780 d3110df3376da5a98c5c4d962fa8a687 219 Gene3D G3DSA:1.10.1240.10 4 78 1.6E-7 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_09780 d3110df3376da5a98c5c4d962fa8a687 219 SUPERFAMILY SSF52242 88 186 3.79E-17 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 Gene3D G3DSA:3.30.450.20 60 203 1.3E-15 T 15-10-2018 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 SUPERFAMILY SSF55874 259 419 1.96E-37 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 6.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 6.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 6.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 6.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 SUPERFAMILY SSF47384 200 270 7.06E-15 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 72 196 1.8E-7 T 15-10-2018 IPR000014 PAS domain C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 416 3.7E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 Gene3D G3DSA:1.10.287.130 209 266 3.4E-17 T 15-10-2018 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 Pfam PF08448 PAS fold 79 192 1.4E-11 T 15-10-2018 IPR013656 PAS fold-4 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 Gene3D G3DSA:3.30.565.10 269 422 2.8E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 268 4.0E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 SUPERFAMILY SSF55785 66 189 2.44E-11 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 SMART SM00388 206 269 8.3E-18 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_17980 457e3b6daf04e2ca90a0f82f1d5f80bb 427 SMART SM00387 311 418 3.1E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18790 c6c3846fc4ea8eec6e1b8beef46791d0 142 Gene3D G3DSA:3.10.180.10 1 135 4.2E-41 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_18790 c6c3846fc4ea8eec6e1b8beef46791d0 142 SUPERFAMILY SSF54593 1 129 1.22E-28 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_18790 c6c3846fc4ea8eec6e1b8beef46791d0 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 5.3E-14 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_18790 c6c3846fc4ea8eec6e1b8beef46791d0 142 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 1 138 42.935 T 15-10-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 C2I28_15130 af0780758739a4ff3c09a822b6f89e7c 492 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 156 181 - T 15-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I28_15130 af0780758739a4ff3c09a822b6f89e7c 492 Gene3D G3DSA:1.20.1730.10 22 492 1.6E-100 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_15130 af0780758739a4ff3c09a822b6f89e7c 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 5 485 1.8E-224 T 15-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 C2I28_15130 af0780758739a4ff3c09a822b6f89e7c 492 Pfam PF00474 Sodium:solute symporter family 34 432 2.3E-108 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_15130 af0780758739a4ff3c09a822b6f89e7c 492 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 15-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I28_15130 af0780758739a4ff3c09a822b6f89e7c 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 432 1.7E-101 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_06980 fd062731812234c8f92bda740058f290 958 SUPERFAMILY SSF52540 615 908 8.96E-52 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06980 fd062731812234c8f92bda740058f290 958 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_06980 fd062731812234c8f92bda740058f290 958 Gene3D G3DSA:1.10.8.280 286 403 3.4E-255 T 15-10-2018 C2I28_06980 fd062731812234c8f92bda740058f290 958 Gene3D G3DSA:3.40.50.300 613 935 2.3E-147 T 15-10-2018 C2I28_06980 fd062731812234c8f92bda740058f290 958 Pfam PF00005 ABC transporter 623 859 6.3E-10 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_06980 fd062731812234c8f92bda740058f290 958 Gene3D G3DSA:1.20.1580.10 692 829 2.3E-147 T 15-10-2018 C2I28_06980 fd062731812234c8f92bda740058f290 958 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 939 23.605 T 15-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 C2I28_06980 fd062731812234c8f92bda740058f290 958 SMART SM00382 25 564 19.0 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_06980 fd062731812234c8f92bda740058f290 958 SMART SM00382 632 954 0.001 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_06980 fd062731812234c8f92bda740058f290 958 Gene3D G3DSA:3.40.50.300 7 594 3.4E-255 T 15-10-2018 C2I28_06980 fd062731812234c8f92bda740058f290 958 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_06980 fd062731812234c8f92bda740058f290 958 SUPERFAMILY SSF52540 10 569 6.14E-48 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06980 fd062731812234c8f92bda740058f290 958 Gene3D G3DSA:3.30.190.20 132 241 3.4E-255 T 15-10-2018 C2I28_06980 fd062731812234c8f92bda740058f290 958 Gene3D G3DSA:1.20.1580.10 92 492 3.4E-255 T 15-10-2018 C2I28_06980 fd062731812234c8f92bda740058f290 958 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 924 0.0 T 15-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 C2I28_20400 dceaeb4faa78e936f605b0b6ec1f6891 369 Gene3D G3DSA:3.60.21.10 146 335 1.6E-23 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_20400 dceaeb4faa78e936f605b0b6ec1f6891 369 SUPERFAMILY SSF56300 146 362 5.76E-32 T 15-10-2018 C2I28_20400 dceaeb4faa78e936f605b0b6ec1f6891 369 Pfam PF00149 Calcineurin-like phosphoesterase 148 311 3.9E-16 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 SUPERFAMILY SSF51735 95 279 6.35E-59 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 310 1.6E-34 T 15-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 15-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Gene3D G3DSA:3.30.70.260 451 524 5.6E-21 T 15-10-2018 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Gene3D G3DSA:3.40.50.720 5 302 1.4E-114 T 15-10-2018 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 SUPERFAMILY SSF52283 14 126 4.91E-34 T 15-10-2018 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 15-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Pfam PF01842 ACT domain 452 512 3.6E-7 T 15-10-2018 IPR002912 ACT domain C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 524 1.8E-212 T 15-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Gene3D G3DSA:3.30.1330.90 315 450 8.2E-36 T 15-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 SUPERFAMILY SSF143548 316 446 1.1E-35 T 15-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Gene3D G3DSA:3.40.50.720 95 276 1.4E-114 T 15-10-2018 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 2.4E-61 T 15-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 SUPERFAMILY SSF55021 442 521 3.62E-17 T 15-10-2018 C2I28_03390 1522d716ac7860d0af4edccabdb6c728 524 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 141 168 - T 15-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 SUPERFAMILY SSF52540 3 213 7.67E-27 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 Gene3D G3DSA:3.40.50.300 2 143 1.1E-39 T 15-10-2018 C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 335 1.9E-82 T 15-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 Gene3D G3DSA:1.20.272.10 214 338 2.8E-38 T 15-10-2018 C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 SUPERFAMILY SSF48019 217 336 2.38E-24 T 15-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 Pfam PF06144 DNA polymerase III, delta subunit 18 193 6.3E-45 T 15-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 C2I28_04420 378f6becb93a04abf5dd3f8866b709c8 338 Gene3D G3DSA:1.10.8.60 144 213 9.5E-11 T 15-10-2018 C2I28_23975 1a8ac5592fcd28deea2ae5ece4f7df3a 235 Gene3D G3DSA:3.30.240.20 169 229 1.2E-13 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_23975 1a8ac5592fcd28deea2ae5ece4f7df3a 235 Pfam PF04239 Protein of unknown function (DUF421) 88 204 5.5E-29 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_23975 1a8ac5592fcd28deea2ae5ece4f7df3a 235 Gene3D G3DSA:3.30.240.20 80 154 5.5E-25 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 679 695 - T 15-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 PIRSF PIRSF037677 154 835 1.1E-135 T 15-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 PIRSF PIRSF037677 1 169 3.1E-32 T 15-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 SUPERFAMILY SSF53150 114 269 2.09E-32 T 15-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Gene3D G3DSA:1.10.1420.10 390 526 3.9E-103 T 15-10-2018 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Pfam PF05190 MutS family domain IV 418 509 6.6E-31 T 15-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 SUPERFAMILY SSF48334 256 555 6.28E-89 T 15-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Pfam PF05192 MutS domain III 261 550 1.2E-42 T 15-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Gene3D G3DSA:3.30.420.110 124 250 4.0E-15 T 15-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Gene3D G3DSA:3.40.1170.10 1 117 7.7E-48 T 15-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 SUPERFAMILY SSF55271 2 112 5.62E-42 T 15-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 SMART SM00533 273 581 8.0E-108 T 15-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Pfam PF05188 MutS domain II 125 242 1.7E-10 T 15-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 874 25.623 T 15-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 SMART SM00534 598 785 8.1E-120 T 15-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Pfam PF01624 MutS domain I 5 116 1.2E-45 T 15-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 SUPERFAMILY SSF52540 558 789 6.76E-63 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Pfam PF00488 MutS domain V 602 788 1.2E-84 T 15-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 880 0.0 T 15-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Gene3D G3DSA:1.10.1420.10 255 551 3.9E-103 T 15-10-2018 C2I28_02105 e32a26fca7eadc9b5f0c1953a9738f16 885 Gene3D G3DSA:3.40.50.300 560 865 9.0E-107 T 15-10-2018 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 Pfam PF01590 GAF domain 63 135 5.0E-7 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 SMART SM00387 270 378 1.9E-31 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 SMART SM00388 165 228 4.5E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 4.3E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 323 4.3E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 4.3E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 337 4.3E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 Gene3D G3DSA:3.30.450.40 6 148 2.7E-13 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 SUPERFAMILY SSF47384 161 226 4.12E-12 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 SMART SM00065 6 152 3.1E-4 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 SUPERFAMILY SSF55781 11 144 3.68E-15 T 15-10-2018 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 Gene3D G3DSA:1.10.287.130 150 225 1.4E-15 T 15-10-2018 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 223 1.6E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 Gene3D G3DSA:3.30.565.10 226 378 5.3E-41 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 SUPERFAMILY SSF55874 223 376 5.37E-37 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24325 8eea7297a7df6d311b6054cc579b2882 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 271 377 1.9E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26765 81edf0b4944972029594381a57018f81 366 SUPERFAMILY SSF51556 52 316 1.62E-63 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_26765 81edf0b4944972029594381a57018f81 366 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 4 364 2.2E-161 T 15-10-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 C2I28_26765 81edf0b4944972029594381a57018f81 366 Gene3D G3DSA:2.30.40.10 6 361 5.2E-111 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_26765 81edf0b4944972029594381a57018f81 366 SUPERFAMILY SSF51338 5 364 1.54E-13 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_26765 81edf0b4944972029594381a57018f81 366 PIRSF PIRSF039004 1 366 5.1E-129 T 15-10-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 C2I28_26765 81edf0b4944972029594381a57018f81 366 Gene3D G3DSA:3.20.20.140 52 316 5.2E-111 T 15-10-2018 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 Gene3D G3DSA:3.40.50.300 3 185 8.8E-52 T 15-10-2018 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 Gene3D G3DSA:3.30.300.20 186 300 3.7E-44 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 6.8E-112 T 15-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 4.2E-5 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 4.2E-5 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 168 3.2E-29 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 1.8E-25 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 SUPERFAMILY SSF52540 11 206 1.19E-51 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 Pfam PF07650 KH domain 208 285 9.1E-22 T 15-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 SUPERFAMILY SSF54814 182 297 3.66E-43 T 15-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I28_04295 5d59e6ebc4d902f383bbf8f20e26dd85 301 Hamap MF_00367 GTPase Era [era]. 6 296 39.381 T 15-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_24140 625eb31dffd88a9e996f2543d983c82e 311 Gene3D G3DSA:1.10.10.10 1 63 9.9E-9 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24140 625eb31dffd88a9e996f2543d983c82e 311 Pfam PF08279 HTH domain 10 61 1.1E-13 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_24140 625eb31dffd88a9e996f2543d983c82e 311 Pfam PF13280 WYL domain 139 306 5.5E-25 T 15-10-2018 IPR026881 WYL domain C2I28_24140 625eb31dffd88a9e996f2543d983c82e 311 SUPERFAMILY SSF46785 4 63 1.29E-8 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24140 625eb31dffd88a9e996f2543d983c82e 311 PIRSF PIRSF016838 1 311 1.6E-15 T 15-10-2018 IPR028349 Protein PafC C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 SUPERFAMILY SSF56784 497 798 6.05E-63 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 ProSitePatterns PS01047 Heavy-metal-associated domain. 80 109 - T 15-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 15-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 712 3.1E-46 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Gene3D G3DSA:3.40.1110.10 510 630 7.0E-99 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Gene3D G3DSA:3.30.70.100 73 151 3.1E-24 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 SUPERFAMILY SSF55008 75 145 9.03E-22 T 15-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Gene3D G3DSA:3.40.50.1000 480 750 7.0E-99 T 15-10-2018 IPR023214 HAD superfamily C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Pfam PF00122 E1-E2 ATPase 298 478 4.9E-57 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 800 6.0E-203 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 SUPERFAMILY SSF81653 301 397 8.5E-29 T 15-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 655 4.5E-28 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 698 717 4.5E-28 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 4.5E-28 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 513 4.5E-28 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 634 4.5E-28 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 721 733 4.5E-28 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 270 785 4.4E-95 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 33 56 8.9E-13 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 8.9E-13 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00942 Copper-transporting ATPase 1 signature 7 32 8.9E-13 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 SUPERFAMILY SSF81665 263 772 4.58E-11 T 15-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 801 6.6E-189 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 287 305 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 420 434 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 675 692 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 267 286 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 215 234 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 732 746 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 90 104 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 119 139 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 PRINTS PR00943 Copper-transporting ATPase signature 482 497 6.4E-20 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 SUPERFAMILY SSF55008 3 72 1.96E-20 T 15-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Pfam PF00403 Heavy-metal-associated domain 78 137 9.5E-15 T 15-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Pfam PF00403 Heavy-metal-associated domain 9 69 6.4E-15 T 15-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 71 1.0E-11 T 15-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 139 2.5E-11 T 15-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Gene3D G3DSA:2.70.150.20 290 402 3.1E-43 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 Gene3D G3DSA:3.30.70.100 2 72 1.7E-23 T 15-10-2018 C2I28_17510 df73b1ce64d9572848f4e126df1956b9 805 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 501 507 - T 15-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I28_04465 f01a03989cf0c137253f5ac08e956097 190 SUPERFAMILY SSF52374 2 189 1.53E-54 T 15-10-2018 C2I28_04465 f01a03989cf0c137253f5ac08e956097 190 Gene3D G3DSA:3.40.50.620 1 188 5.9E-67 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_04465 f01a03989cf0c137253f5ac08e956097 190 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 31.526 T 15-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 C2I28_04465 f01a03989cf0c137253f5ac08e956097 190 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 1.9E-57 T 15-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 C2I28_04465 f01a03989cf0c137253f5ac08e956097 190 Pfam PF01467 Cytidylyltransferase-like 6 162 3.8E-31 T 15-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I28_04465 f01a03989cf0c137253f5ac08e956097 190 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 65 1.1E-9 T 15-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I28_10985 c0efaf7f5310659b3250cf4282a198f7 448 Gene3D G3DSA:3.30.470.20 308 437 2.1E-12 T 15-10-2018 C2I28_10985 c0efaf7f5310659b3250cf4282a198f7 448 SUPERFAMILY SSF56059 213 413 3.33E-19 T 15-10-2018 C2I28_10985 c0efaf7f5310659b3250cf4282a198f7 448 Pfam PF14398 YheC/D like ATP-grasp 187 436 8.9E-74 T 15-10-2018 IPR026838 Endospore coat-associated protein YheC/D C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 SUPERFAMILY SSF46785 1 80 4.61E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 SUPERFAMILY SSF53850 88 283 2.72E-20 T 15-10-2018 C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 Gene3D G3DSA:1.10.10.10 1 89 3.2E-23 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 Gene3D G3DSA:3.40.190.290 90 284 2.4E-20 T 15-10-2018 C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 Pfam PF03466 LysR substrate binding domain 87 283 7.6E-24 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_13275 af4178c7ffdacaaffe5ad7a524b6b992 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.8E-17 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 SMART SM01232 126 221 1.4E-15 T 15-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 104 2.7E-9 T 15-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 Gene3D G3DSA:1.10.8.50 128 272 4.8E-33 T 15-10-2018 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 SUPERFAMILY SSF81624 2 127 1.7E-20 T 15-10-2018 IPR035937 MutM-like, N-terminal C2I28_12565 310c3609696c985c0400763de5de2b1e 272 SUPERFAMILY SSF46946 126 216 7.33E-18 T 15-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 127 215 1.2E-13 T 15-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 SUPERFAMILY SSF57716 234 272 1.97E-9 T 15-10-2018 C2I28_12565 310c3609696c985c0400763de5de2b1e 272 Gene3D G3DSA:3.20.190.10 2 127 4.8E-27 T 15-10-2018 IPR035937 MutM-like, N-terminal C2I28_12565 310c3609696c985c0400763de5de2b1e 272 SMART SM00898 2 110 4.1E-8 T 15-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 Pfam PF00696 Amino acid kinase family 7 235 8.3E-48 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 TIGRFAM TIGR01027 proB: glutamate 5-kinase 7 341 6.4E-123 T 15-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 Pfam PF01472 PUA domain 281 341 2.8E-10 T 15-10-2018 IPR002478 PUA domain GO:0003723 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 Hamap MF_00456 Glutamate 5-kinase [proB]. 7 261 38.073 T 15-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 SMART SM00359 281 357 0.0014 T 15-10-2018 IPR002478 PUA domain GO:0003723 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 Gene3D G3DSA:3.40.1160.10 2 265 2.1E-90 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 ProSitePatterns PS00902 Glutamate 5-kinase signature. 209 226 - T 15-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 SUPERFAMILY SSF88697 281 341 1.68E-8 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 Gene3D G3DSA:2.30.130.10 270 348 1.1E-15 T 15-10-2018 IPR036974 PUA domain superfamily GO:0003723 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 SUPERFAMILY SSF53633 7 258 1.06E-70 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 PRINTS PR00474 Glutamate 5-kinase family signature 150 177 2.6E-53 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 PRINTS PR00474 Glutamate 5-kinase family signature 118 139 2.6E-53 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 PRINTS PR00474 Glutamate 5-kinase family signature 78 106 2.6E-53 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 PRINTS PR00474 Glutamate 5-kinase family signature 211 231 2.6E-53 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 2.6E-53 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_19510 b03a9fd9f699a618c0bb741e02cc88a0 368 PIRSF PIRSF000729 3 350 1.5E-131 T 15-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 C2I28_08375 915f8eaf625c611f99eace0f4e571f40 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 2.5E-36 T 15-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 C2I28_08375 915f8eaf625c611f99eace0f4e571f40 76 ProDom PD057826 YABK 4 76 5.0E-25 T 15-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SMART SM00388 178 243 3.8E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SMART SM00387 286 393 7.9E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SUPERFAMILY SSF55874 245 394 5.37E-35 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SUPERFAMILY SSF55785 54 166 9.87E-22 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SUPERFAMILY SSF47384 172 241 1.57E-11 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 Gene3D G3DSA:1.10.287.130 181 239 5.4E-14 T 15-10-2018 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 Pfam PF00512 His Kinase A (phospho-acceptor) domain 180 241 4.6E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SMART SM00091 49 115 2.9E-7 T 15-10-2018 IPR000014 PAS domain C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 371 1.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 1.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 352 1.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 1.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 Gene3D G3DSA:3.30.450.20 46 177 2.6E-22 T 15-10-2018 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 Pfam PF08448 PAS fold 55 165 2.6E-12 T 15-10-2018 IPR013656 PAS fold-4 C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 Gene3D G3DSA:3.30.565.10 245 397 6.2E-39 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 SMART SM00086 121 163 1.7E-4 T 15-10-2018 IPR001610 PAC motif C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 169 4.8E-17 T 15-10-2018 IPR000014 PAS domain C2I28_01920 37e4df5f97d462db5dd874d9c7fe5678 401 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 392 8.7E-22 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 120 1.6E-60 T 15-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 PIRSF PIRSF006614 1 132 3.4E-63 T 15-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 Pfam PF02142 MGS-like domain 14 107 3.3E-19 T 15-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 SUPERFAMILY SSF52335 1 130 4.32E-54 T 15-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 34.391 T 15-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 SMART SM00851 14 107 1.0E-23 T 15-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 61 - T 15-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 C2I28_14970 cfab76fbc331c8635a519a3ff6279da1 132 Gene3D G3DSA:3.40.50.1380 1 131 2.3E-57 T 15-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 280 7.0E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 252 266 7.0E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 323 7.0E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 304 7.0E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 Gene3D G3DSA:1.10.287.130 124 173 2.2E-33 T 15-10-2018 C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 SUPERFAMILY SSF47384 100 153 1.0E-4 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 SUPERFAMILY SSF55874 175 323 9.3E-32 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 Gene3D G3DSA:3.30.565.10 174 323 2.2E-33 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 SMART SM00387 216 326 3.9E-23 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_24550 1b78eac45c5d520abd8f8bfb68455d17 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 324 7.9E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01380 3e27f2fe44976b09e9fab8da844a45db 269 Gene3D G3DSA:3.40.50.150 2 269 3.7E-43 T 15-10-2018 C2I28_01380 3e27f2fe44976b09e9fab8da844a45db 269 SUPERFAMILY SSF53335 4 268 1.84E-32 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_01380 3e27f2fe44976b09e9fab8da844a45db 269 Pfam PF13649 Methyltransferase domain 41 140 5.8E-18 T 15-10-2018 C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 SUPERFAMILY SSF51419 4 224 1.16E-71 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 5 225 8.7E-52 T 15-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 Gene3D G3DSA:3.20.20.10 1 227 1.2E-74 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 Pfam PF01168 Alanine racemase, N-terminal domain 8 224 5.5E-16 T 15-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 76 90 - T 15-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 PIRSF PIRSF004848 2 227 4.5E-66 T 15-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I28_02905 0655c4e0412c820efd6fd56244287bef 227 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 7 225 27.178 T 15-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SUPERFAMILY SSF55785 361 484 4.19E-7 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SMART SM00388 645 713 2.9E-21 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 761 867 2.1E-22 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF13188 PAS domain 499 546 0.0049 T 15-10-2018 IPR000014 PAS domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SMART SM00448 892 1006 2.4E-21 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Gene3D G3DSA:3.30.450.20 485 624 2.9E-16 T 15-10-2018 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SUPERFAMILY SSF52172 892 1010 1.07E-25 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Gene3D G3DSA:3.30.450.20 391 484 4.2E-6 T 15-10-2018 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF03707 Bacterial signalling protein N terminal repeat 117 167 1.0E-9 T 15-10-2018 IPR005330 MHYT domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF03707 Bacterial signalling protein N terminal repeat 183 239 8.1E-5 T 15-10-2018 IPR005330 MHYT domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF03707 Bacterial signalling protein N terminal repeat 58 106 5.5E-10 T 15-10-2018 IPR005330 MHYT domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SMART SM00387 760 869 3.3E-30 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF08448 PAS fold 412 487 5.1E-5 T 15-10-2018 IPR013656 PAS fold-4 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Gene3D G3DSA:3.40.50.2300 888 1012 5.5E-28 T 15-10-2018 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SUPERFAMILY SSF55785 242 362 1.08E-15 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 PRINTS PR00344 Bacterial sensor protein C-terminal signature 797 811 2.1E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 PRINTS PR00344 Bacterial sensor protein C-terminal signature 829 847 2.1E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 PRINTS PR00344 Bacterial sensor protein C-terminal signature 815 825 2.1E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 PRINTS PR00344 Bacterial sensor protein C-terminal signature 853 866 2.1E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Gene3D G3DSA:1.10.287.130 634 711 7.4E-26 T 15-10-2018 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SMART SM00091 498 568 0.0055 T 15-10-2018 IPR000014 PAS domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SMART SM00091 254 320 0.0091 T 15-10-2018 IPR000014 PAS domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SUPERFAMILY SSF55874 702 871 1.83E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Gene3D G3DSA:3.30.450.20 241 389 6.6E-18 T 15-10-2018 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SUPERFAMILY SSF55785 483 616 1.59E-15 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF00072 Response regulator receiver domain 894 1005 2.5E-18 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF13426 PAS domain 267 363 2.1E-5 T 15-10-2018 IPR000014 PAS domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 SUPERFAMILY SSF47384 631 714 4.32E-22 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Gene3D G3DSA:3.30.565.10 712 868 1.2E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 Pfam PF00512 His Kinase A (phospho-acceptor) domain 645 713 1.8E-17 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 252 371 2.2E-16 T 15-10-2018 IPR000014 PAS domain C2I28_14180 e95d46dbe02d9126d05c16ec51a0fb07 1012 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 495 625 5.5E-7 T 15-10-2018 IPR000014 PAS domain C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 497 600 3.4E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 Gene3D G3DSA:3.30.450.20 261 369 3.5E-8 T 15-10-2018 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 Gene3D G3DSA:1.10.287.130 372 448 1.8E-19 T 15-10-2018 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SMART SM00304 206 258 6.1E-5 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SUPERFAMILY SSF47384 381 451 3.14E-13 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 Gene3D G3DSA:3.30.565.10 449 600 1.7E-36 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 547 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 561 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SMART SM00387 496 601 1.4E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SMART SM00388 387 453 1.1E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SUPERFAMILY SSF158472 207 255 6.41E-5 T 15-10-2018 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SUPERFAMILY SSF55874 443 600 1.96E-34 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 Gene3D G3DSA:1.20.1480.50 170 260 5.8E-7 T 15-10-2018 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 Pfam PF00512 His Kinase A (phospho-acceptor) domain 389 451 4.7E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09585 cd83104994a1c6e483088bc5ed4b1fb8 601 SUPERFAMILY SSF55785 268 371 7.23E-5 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 Pfam PF01979 Amidohydrolase family 53 376 6.4E-19 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 2 390 5.5E-173 T 15-10-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 Gene3D G3DSA:3.20.20.140 58 343 4.6E-154 T 15-10-2018 C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 SUPERFAMILY SSF51556 57 347 8.49E-75 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 Gene3D G3DSA:2.30.40.10 4 390 4.6E-154 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 SUPERFAMILY SSF51338 2 389 5.52E-18 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_16035 a56ec09669e7cf79803f41d08f56f622 390 PIRSF PIRSF001238 1 390 4.0E-166 T 15-10-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 C2I28_16415 6cc5754bab3b4500af5f02a5a8ace346 498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_16415 6cc5754bab3b4500af5f02a5a8ace346 498 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 491 1.4E-16 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_16415 6cc5754bab3b4500af5f02a5a8ace346 498 Gene3D G3DSA:3.30.300.30 402 498 1.5E-27 T 15-10-2018 C2I28_16415 6cc5754bab3b4500af5f02a5a8ace346 498 Gene3D G3DSA:3.40.50.12780 1 401 3.9E-107 T 15-10-2018 C2I28_16415 6cc5754bab3b4500af5f02a5a8ace346 498 SUPERFAMILY SSF56801 2 498 2.62E-139 T 15-10-2018 C2I28_16415 6cc5754bab3b4500af5f02a5a8ace346 498 Pfam PF00501 AMP-binding enzyme 8 408 7.7E-98 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_17380 116b2a0d5ddc876dd6b1261d32c563bc 404 SUPERFAMILY SSF53383 24 394 9.65E-112 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_17380 116b2a0d5ddc876dd6b1261d32c563bc 404 Gene3D G3DSA:3.40.640.10 10 260 5.2E-83 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_17380 116b2a0d5ddc876dd6b1261d32c563bc 404 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 393 1.2E-134 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_17380 116b2a0d5ddc876dd6b1261d32c563bc 404 PIRSF PIRSF001434 1 397 8.9E-145 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_17380 116b2a0d5ddc876dd6b1261d32c563bc 404 Gene3D G3DSA:3.90.1150.10 261 396 6.8E-47 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 SMART SM00382 538 682 2.5E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 SMART SM00382 201 345 6.6E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 318 1.6E-13 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 605 6.2E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 663 6.2E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 6.2E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 616 634 6.2E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 15-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Gene3D G3DSA:3.40.50.300 490 713 1.1E-91 T 15-10-2018 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Gene3D G3DSA:1.10.1780.10 1 150 1.0E-61 T 15-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 794 1.5E-27 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 SUPERFAMILY SSF52540 162 472 9.82E-79 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Pfam PF07724 AAA domain (Cdc48 subfamily) 537 709 3.0E-57 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Gene3D G3DSA:3.40.50.300 153 344 4.0E-72 T 15-10-2018 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 SUPERFAMILY SSF52540 487 803 2.13E-84 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Gene3D G3DSA:1.10.8.60 715 809 1.4E-30 T 15-10-2018 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Gene3D G3DSA:4.10.860.10 410 468 3.0E-52 T 15-10-2018 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 1.1E-16 T 15-10-2018 IPR004176 Clp, N-terminal C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 1.0E-17 T 15-10-2018 IPR004176 Clp, N-terminal C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 SUPERFAMILY SSF81923 5 150 7.36E-33 T 15-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Gene3D G3DSA:1.10.8.60 347 482 3.0E-52 T 15-10-2018 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 Pfam PF02151 UvrB/uvrC motif 418 452 5.3E-6 T 15-10-2018 IPR001943 UVR domain GO:0005515 C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 SMART SM01086 715 804 2.7E-38 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_08540 40369703dfb19bdd5de0ffb25dc29371 813 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 572 590 - T 15-10-2018 IPR028299 ClpA/B, conserved site 2 C2I28_00765 f18308a90f34552fa0e173bb0960020d 288 Pfam PF01522 Polysaccharide deacetylase 108 247 1.6E-29 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_00765 f18308a90f34552fa0e173bb0960020d 288 Gene3D G3DSA:3.20.20.370 38 283 7.0E-62 T 15-10-2018 C2I28_00765 f18308a90f34552fa0e173bb0960020d 288 SUPERFAMILY SSF88713 74 247 1.85E-36 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_00765 f18308a90f34552fa0e173bb0960020d 288 TIGRFAM TIGR03933 PIA_icaB: intercellular adhesin biosynthesis polysaccharide N-deacetylase 42 282 1.5E-74 T 15-10-2018 IPR023872 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase GO:0016811 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 SUPERFAMILY SSF53850 105 314 4.48E-41 T 15-10-2018 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 Gene3D G3DSA:3.40.190.10 184 285 1.2E-41 T 15-10-2018 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 80 6.7E-17 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 Gene3D G3DSA:1.10.10.10 14 101 1.3E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 SUPERFAMILY SSF46785 20 104 1.3E-18 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 57 2.4E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 68 2.4E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 2.4E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 Gene3D G3DSA:3.40.190.10 108 308 1.2E-41 T 15-10-2018 C2I28_16285 45d23715dd40c75d726612aaab4e2cd0 325 Pfam PF03466 LysR substrate binding domain 105 308 7.4E-43 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 Pfam PF01546 Peptidase family M20/M25/M40 77 389 1.1E-32 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 SUPERFAMILY SSF55031 189 300 5.89E-32 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 Gene3D G3DSA:3.40.630.10 19 377 5.0E-144 T 15-10-2018 C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 Gene3D G3DSA:3.30.70.360 186 300 5.0E-144 T 15-10-2018 C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 SUPERFAMILY SSF53187 10 392 1.05E-82 T 15-10-2018 C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 PIRSF PIRSF005962 4 394 4.7E-131 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 380 6.7E-119 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_24535 fd7ecda3ae4a9225267c6d0491886b12 394 Pfam PF07687 Peptidase dimerisation domain 190 284 4.0E-13 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_07095 d38f1c1fee19a3b7a3a1c6a4374c0657 465 Gene3D G3DSA:1.20.1740.10 7 463 1.9E-67 T 15-10-2018 C2I28_07095 d38f1c1fee19a3b7a3a1c6a4374c0657 465 Pfam PF00324 Amino acid permease 15 456 9.0E-114 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_07095 d38f1c1fee19a3b7a3a1c6a4374c0657 465 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_07095 d38f1c1fee19a3b7a3a1c6a4374c0657 465 PIRSF PIRSF006060 1 464 6.7E-78 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_09915 2be5cabfcaf6f41a13f291b071dc23f9 248 SUPERFAMILY SSF55797 124 245 1.1E-27 T 15-10-2018 IPR035940 CAP superfamily C2I28_09915 2be5cabfcaf6f41a13f291b071dc23f9 248 Gene3D G3DSA:3.40.33.10 19 246 5.3E-68 T 15-10-2018 IPR035940 CAP superfamily C2I28_09915 2be5cabfcaf6f41a13f291b071dc23f9 248 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 124 247 2.5E-62 T 15-10-2018 IPR014258 CAP domain, YkwD-like C2I28_09915 2be5cabfcaf6f41a13f291b071dc23f9 248 Pfam PF00188 Cysteine-rich secretory protein family 132 245 6.9E-24 T 15-10-2018 IPR014044 CAP domain C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 SUPERFAMILY SSF53187 1 181 1.32E-46 T 15-10-2018 C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 Pfam PF01476 LysM domain 209 253 2.5E-16 T 15-10-2018 IPR018392 LysM domain C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 SMART SM00646 65 176 6.0E-35 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 Gene3D G3DSA:3.10.350.10 193 264 9.6E-20 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 SMART SM00257 208 253 2.5E-17 T 15-10-2018 IPR018392 LysM domain C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 SUPERFAMILY SSF54106 207 253 4.32E-11 T 15-10-2018 C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 SUPERFAMILY SSF47090 271 339 1.12E-16 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 176 1.4E-42 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 Gene3D G3DSA:1.10.101.10 265 343 4.6E-20 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 Pfam PF01471 Putative peptidoglycan binding domain 281 338 6.0E-13 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_02055 720bf01282907c70883ff77603e4c0ee 346 Gene3D G3DSA:3.40.630.40 1 182 6.1E-50 T 15-10-2018 C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 Pfam PF09339 IclR helix-turn-helix domain 9 59 2.3E-13 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 Pfam PF01614 Bacterial transcriptional regulator 124 248 9.0E-42 T 15-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 Gene3D G3DSA:3.30.450.40 79 261 9.1E-66 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 Gene3D G3DSA:1.10.10.10 5 78 1.7E-23 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 SUPERFAMILY SSF46785 7 80 4.94E-17 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 SUPERFAMILY SSF55781 65 253 2.22E-55 T 15-10-2018 C2I28_22465 10be6ea2f5fb1f780897412693c378f6 264 SMART SM00346 7 97 4.9E-27 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_10455 f50badb900071649d0375d693728e76f 371 Gene3D G3DSA:2.40.50.940 223 348 1.2E-30 T 15-10-2018 C2I28_10455 f50badb900071649d0375d693728e76f 371 SUPERFAMILY SSF50331 237 355 1.68E-27 T 15-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I28_10455 f50badb900071649d0375d693728e76f 371 Pfam PF08402 TOBE domain 277 347 5.4E-8 T 15-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 C2I28_10455 f50badb900071649d0375d693728e76f 371 Gene3D G3DSA:3.40.50.300 3 222 1.5E-66 T 15-10-2018 C2I28_10455 f50badb900071649d0375d693728e76f 371 SMART SM00382 29 212 2.7E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_10455 f50badb900071649d0375d693728e76f 371 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_10455 f50badb900071649d0375d693728e76f 371 Gene3D G3DSA:2.40.50.140 284 339 1.2E-30 T 15-10-2018 C2I28_10455 f50badb900071649d0375d693728e76f 371 Pfam PF00005 ABC transporter 21 162 1.7E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_10455 f50badb900071649d0375d693728e76f 371 SUPERFAMILY SSF52540 4 244 1.82E-84 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_27475 41f830793ad2a775c36b3aed2bab8b64 274 Gene3D G3DSA:3.40.50.720 4 214 9.7E-47 T 15-10-2018 C2I28_27475 41f830793ad2a775c36b3aed2bab8b64 274 Pfam PF04321 RmlD substrate binding domain 1 235 7.2E-27 T 15-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 C2I28_27475 41f830793ad2a775c36b3aed2bab8b64 274 Gene3D G3DSA:3.90.25.10 162 237 9.7E-47 T 15-10-2018 C2I28_27475 41f830793ad2a775c36b3aed2bab8b64 274 SUPERFAMILY SSF51735 1 233 3.02E-52 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_22430 68c764b8e5aa811f2c4cca959068c125 198 Pfam PF00924 Mechanosensitive ion channel 75 181 1.0E-29 T 15-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I28_22430 68c764b8e5aa811f2c4cca959068c125 198 SUPERFAMILY SSF50182 116 179 1.5E-14 T 15-10-2018 IPR010920 LSM domain superfamily C2I28_22430 68c764b8e5aa811f2c4cca959068c125 198 SUPERFAMILY SSF82861 27 115 4.97E-11 T 15-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 C2I28_22430 68c764b8e5aa811f2c4cca959068c125 198 Gene3D G3DSA:2.30.30.60 132 180 6.1E-21 T 15-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 Gene3D G3DSA:3.20.20.70 1 222 2.5E-85 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 SUPERFAMILY SSF51569 1 220 1.36E-72 T 15-10-2018 C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 Hamap MF_00494 Probable transaldolase [tal]. 1 221 44.428 T 15-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 216 4.4E-56 T 15-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 9.2E-82 T 15-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_17180 40a596f9386804ac6d3533a9f45ae2e2 222 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_24930 a819c917440d7520bed7762daaa3519a 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.5E-29 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 Gene3D G3DSA:2.40.50.140 1 66 8.1E-30 T 15-10-2018 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 SMART SM00357 3 66 1.2E-29 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 SUPERFAMILY SSF50249 1 65 2.91E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_24930 a819c917440d7520bed7762daaa3519a 67 PIRSF PIRSF002599 1 67 2.3E-25 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 PRINTS PR00050 Cold shock protein signature 24 33 4.8E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 PRINTS PR00050 Cold shock protein signature 4 19 4.8E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_24930 a819c917440d7520bed7762daaa3519a 67 PRINTS PR00050 Cold shock protein signature 39 57 4.8E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 SUPERFAMILY SSF53850 88 279 2.95E-20 T 15-10-2018 C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 SUPERFAMILY SSF46785 4 107 4.7E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 Gene3D G3DSA:3.40.190.290 83 280 1.1E-23 T 15-10-2018 C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.0E-22 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 Pfam PF03466 LysR substrate binding domain 88 278 5.5E-24 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 Gene3D G3DSA:1.10.10.10 1 82 6.1E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-6 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-6 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_25265 46f4202b30916ae44298d72f5864fa7f 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-6 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_23125 7787c65bf71110083d5023504322d8af 423 ProSitePatterns PS00104 EPSP synthase signature 1. 83 97 - T 15-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_23125 7787c65bf71110083d5023504322d8af 423 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 4 423 32.854 T 15-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_23125 7787c65bf71110083d5023504322d8af 423 PIRSF PIRSF000505 1 423 3.4E-121 T 15-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_23125 7787c65bf71110083d5023504322d8af 423 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 8 422 4.1E-134 T 15-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_23125 7787c65bf71110083d5023504322d8af 423 Gene3D G3DSA:3.65.10.10 6 418 2.2E-156 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_23125 7787c65bf71110083d5023504322d8af 423 ProSitePatterns PS00885 EPSP synthase signature 2. 335 353 - T 15-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_23125 7787c65bf71110083d5023504322d8af 423 Gene3D G3DSA:3.65.10.10 16 225 2.2E-156 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_23125 7787c65bf71110083d5023504322d8af 423 SUPERFAMILY SSF55205 3 421 3.92E-136 T 15-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I28_23125 7787c65bf71110083d5023504322d8af 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 4 418 9.1E-126 T 15-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 359 9.2E-146 T 15-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 Gene3D G3DSA:2.160.10.10 275 382 9.3E-24 T 15-10-2018 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 SUPERFAMILY SSF51161 228 361 3.2E-22 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 SUPERFAMILY SSF53448 3 263 1.13E-82 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 15-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 15-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 Pfam PF00483 Nucleotidyl transferase 8 259 1.9E-69 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 Gene3D G3DSA:3.90.550.10 2 274 3.8E-92 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 377 48.799 T 15-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I28_06040 c273e701dba8ca5297650cebc3c8e838 383 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 15-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 Gene3D G3DSA:3.40.50.980 34 344 1.5E-117 T 15-10-2018 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 Pfam PF00501 AMP-binding enzyme 14 429 7.8E-106 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 Gene3D G3DSA:3.30.300.30 423 525 4.6E-32 T 15-10-2018 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 180 191 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_06170 067d7894a981794141ddbe47156f37e8 528 Gene3D G3DSA:3.40.50.980 37 196 1.5E-117 T 15-10-2018 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 Gene3D G3DSA:2.30.38.10 345 422 1.5E-117 T 15-10-2018 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 SUPERFAMILY SSF56801 5 523 1.03E-150 T 15-10-2018 C2I28_06170 067d7894a981794141ddbe47156f37e8 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 438 513 5.2E-17 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 218 340 1.6E-23 T 15-10-2018 IPR000014 PAS domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 348 474 2.5E-14 T 15-10-2018 IPR000014 PAS domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Pfam PF13426 PAS domain 230 332 2.2E-15 T 15-10-2018 IPR000014 PAS domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SUPERFAMILY SSF47384 476 545 1.18E-12 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Pfam PF13188 PAS domain 353 412 7.0E-7 T 15-10-2018 IPR000014 PAS domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 627 641 2.3E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 674 2.3E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 645 655 2.3E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 693 2.3E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Pfam PF07694 5TMR of 5TMR-LYT 28 141 1.2E-7 T 15-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 591 694 2.1E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SMART SM00387 589 695 2.3E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SUPERFAMILY SSF55785 342 464 8.03E-17 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Gene3D G3DSA:3.30.450.20 348 465 6.2E-20 T 15-10-2018 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SMART SM00388 483 547 4.9E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Gene3D G3DSA:3.30.565.10 548 695 8.8E-43 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SMART SM00086 291 333 1.2E-6 T 15-10-2018 IPR001610 PAC motif C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SMART SM00086 428 468 65.0 T 15-10-2018 IPR001610 PAC motif C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SMART SM00091 352 422 0.0021 T 15-10-2018 IPR000014 PAS domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SMART SM00091 219 284 2.4E-8 T 15-10-2018 IPR000014 PAS domain C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Gene3D G3DSA:1.10.287.130 469 546 1.2E-18 T 15-10-2018 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Pfam PF00512 His Kinase A (phospho-acceptor) domain 484 544 2.3E-11 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 Gene3D G3DSA:3.30.450.20 212 347 1.5E-27 T 15-10-2018 C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SUPERFAMILY SSF55874 544 694 7.47E-39 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19675 58fca084e8179cf43e0f700571709a25 695 SUPERFAMILY SSF55785 210 331 8.2E-23 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_02290 26608bd913373a78497191a221193280 708 SMART SM00322 553 617 4.3E-11 T 15-10-2018 IPR004087 K Homology domain GO:0003676 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 2.2E-20 T 15-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 1.8E-19 T 15-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 SUPERFAMILY SSF54211 9 144 4.71E-49 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_02290 26608bd913373a78497191a221193280 708 Gene3D G3DSA:3.30.230.70 1 230 1.7E-83 T 15-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 SUPERFAMILY SSF55666 451 550 1.83E-29 T 15-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 Gene3D G3DSA:3.30.230.70 236 550 1.4E-120 T 15-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 SUPERFAMILY SSF50249 621 703 6.86E-20 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_02290 26608bd913373a78497191a221193280 708 PIRSF PIRSF005499 2 708 2.0E-301 T 15-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF00013 KH domain 557 615 6.9E-9 T 15-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 1.8E-14 T 15-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF00575 S1 RNA binding domain 620 691 1.4E-17 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_02290 26608bd913373a78497191a221193280 708 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 692 0.0 T 15-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I28_02290 26608bd913373a78497191a221193280 708 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.169 T 15-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 C2I28_02290 26608bd913373a78497191a221193280 708 SUPERFAMILY SSF55666 145 236 8.64E-31 T 15-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 SUPERFAMILY SSF54791 556 641 1.48E-23 T 15-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I28_02290 26608bd913373a78497191a221193280 708 SUPERFAMILY SSF54211 293 489 5.57E-50 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_02290 26608bd913373a78497191a221193280 708 Gene3D G3DSA:2.40.50.140 623 694 6.3E-26 T 15-10-2018 C2I28_02290 26608bd913373a78497191a221193280 708 SMART SM00316 621 691 1.1E-23 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 7.8E-16 T 15-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 Pfam PF03725 3' exoribonuclease family, domain 2 460 530 4.8E-8 T 15-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_02290 26608bd913373a78497191a221193280 708 Gene3D G3DSA:3.30.1370.10 551 622 5.1E-20 T 15-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 128 3.9E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 SUPERFAMILY SSF56784 1 168 9.21E-37 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 132 3.6E-27 T 15-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 Pfam PF13242 HAD-hyrolase-like 89 164 7.3E-18 T 15-10-2018 C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 136 8.1E-24 T 15-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 Gene3D G3DSA:3.40.50.1000 3 171 8.0E-45 T 15-10-2018 IPR023214 HAD superfamily C2I28_23945 94ad424d98b27ffc4e7d236d32122b3d 184 PIRSF PIRSF004682 1 169 2.4E-39 T 15-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 4.0E-29 T 15-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 113 194 1.9E-12 T 15-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 SUPERFAMILY SSF51735 102 274 3.44E-41 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 Gene3D G3DSA:3.40.50.10860 5 263 3.4E-94 T 15-10-2018 C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 Gene3D G3DSA:3.40.50.720 101 242 3.4E-94 T 15-10-2018 C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 SUPERFAMILY SSF53223 3 101 3.28E-33 T 15-10-2018 C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 274 33.768 T 15-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 C2I28_04475 d13eb51743a12279d5d22f48b0797603 279 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 276 3.8E-86 T 15-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 C2I28_03745 123cd1cbb7abdbd395372dbdccdb2240 678 SUPERFAMILY SSF51703 7 487 5.49E-118 T 15-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_03745 123cd1cbb7abdbd395372dbdccdb2240 678 SUPERFAMILY SSF52242 531 673 3.77E-9 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_03745 123cd1cbb7abdbd395372dbdccdb2240 678 Gene3D G3DSA:3.40.50.280 560 675 2.8E-6 T 15-10-2018 C2I28_03745 123cd1cbb7abdbd395372dbdccdb2240 678 Gene3D G3DSA:3.20.20.240 3 524 8.9E-134 T 15-10-2018 C2I28_03745 123cd1cbb7abdbd395372dbdccdb2240 678 Pfam PF01642 Methylmalonyl-CoA mutase 34 489 1.4E-122 T 15-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_20115 1923fede31f410913ac55cd54ff191ed 268 Pfam PF05675 Protein of unknown function (DUF817) 3 237 8.4E-106 T 15-10-2018 IPR008535 Protein of unknown function DUF817 C2I28_20115 1923fede31f410913ac55cd54ff191ed 268 PIRSF PIRSF009141 1 259 1.7E-124 T 15-10-2018 IPR008535 Protein of unknown function DUF817 C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 SUPERFAMILY SSF49899 342 494 1.74E-36 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 SMART SM00640 36 458 1.6E-152 T 15-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 345 487 1.3E-32 T 15-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 468 6.3E-155 T 15-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 36 342 3.4E-108 T 15-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 Gene3D G3DSA:2.60.120.560 357 493 2.8E-32 T 15-10-2018 C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 SUPERFAMILY SSF75005 27 343 2.36E-115 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_00200 da53115bd9fb484ae714b2b0a5312c0d 504 Gene3D G3DSA:2.115.10.20 2 356 2.8E-130 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 Gene3D G3DSA:2.60.40.1180 624 712 5.5E-18 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 SUPERFAMILY SSF51445 199 623 5.98E-125 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 SMART SM00642 221 621 4.9E-7 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 Gene3D G3DSA:2.60.40.2320 1 96 3.5E-28 T 15-10-2018 C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 Pfam PF00128 Alpha amylase, catalytic domain 375 576 2.0E-7 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 SUPERFAMILY SSF81296 98 198 8.71E-22 T 15-10-2018 IPR014756 Immunoglobulin E-set C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 Gene3D G3DSA:2.60.40.10 97 201 8.5E-25 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 106 183 1.1E-12 T 15-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 94 687 4.0E-246 T 15-10-2018 IPR011840 Pullulanase, type I C2I28_05735 71830ebcb5d847febc4e90f793e04033 713 Gene3D G3DSA:3.20.20.80 202 623 2.3E-175 T 15-10-2018 C2I28_07555 b2b6c999dbce9a00b819e62d41e04ef2 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 2.5E-27 T 15-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 C2I28_07555 b2b6c999dbce9a00b819e62d41e04ef2 61 Pfam PF01361 Tautomerase enzyme 2 60 9.7E-23 T 15-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 C2I28_07555 b2b6c999dbce9a00b819e62d41e04ef2 61 Gene3D G3DSA:3.30.429.10 1 60 1.4E-27 T 15-10-2018 IPR014347 Tautomerase/MIF superfamily C2I28_07555 b2b6c999dbce9a00b819e62d41e04ef2 61 SUPERFAMILY SSF55331 2 60 1.83E-19 T 15-10-2018 IPR014347 Tautomerase/MIF superfamily C2I28_10380 4e2aef16827c4281ab83f52e64c80689 370 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 369 2.1E-62 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_10380 4e2aef16827c4281ab83f52e64c80689 370 Gene3D G3DSA:3.30.300.210 217 370 6.6E-20 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_10380 4e2aef16827c4281ab83f52e64c80689 370 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 202 367 5.1E-26 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 Gene3D G3DSA:1.10.10.10 718 781 2.4E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 SUPERFAMILY SSF52540 394 691 2.12E-48 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 SUPERFAMILY SSF46785 715 780 1.9E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 SMART SM00843 714 779 2.2E-41 T 15-10-2018 IPR018541 FtsK gamma domain C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 SMART SM00382 456 640 1.6E-4 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 Pfam PF01580 FtsK/SpoIIIE family 421 619 5.4E-66 T 15-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 Pfam PF09397 Ftsk gamma domain 717 776 1.7E-30 T 15-10-2018 IPR018541 FtsK gamma domain C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 Gene3D G3DSA:3.40.50.300 418 705 8.2E-113 T 15-10-2018 C2I28_02230 4fbb5a03fcde4ea075615e9bfe24dbaa 785 Gene3D G3DSA:3.30.980.40 313 416 2.3E-38 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Gene3D G3DSA:1.20.1060.10 490 604 2.6E-45 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SMART SM00279 173 208 9.3E-18 T 15-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SUPERFAMILY SSF56672 469 875 2.45E-159 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SMART SM00474 299 465 9.0E-15 T 15-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Gene3D G3DSA:1.10.150.20 174 247 5.9E-100 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 170 3.1E-55 T 15-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SUPERFAMILY SSF47807 171 285 1.0E-32 T 15-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 ProSitePatterns PS00447 DNA polymerase family A signature. 701 720 - T 15-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SMART SM00482 632 839 1.6E-117 T 15-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SUPERFAMILY SSF88723 2 170 2.8E-56 T 15-10-2018 IPR029060 PIN-like domain superfamily C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Pfam PF00476 DNA polymerase family A 498 873 1.1E-161 T 15-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Gene3D G3DSA:3.40.50.1010 5 278 5.9E-100 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 264 8.6E-34 T 15-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SUPERFAMILY SSF53098 299 466 9.56E-42 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 TIGRFAM TIGR00593 pola: DNA polymerase I 5 875 0.0 T 15-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Gene3D G3DSA:3.30.420.10 296 489 7.4E-66 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Gene3D G3DSA:1.10.150.20 656 799 1.4E-109 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 Gene3D G3DSA:3.30.70.370 610 871 1.4E-109 T 15-10-2018 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 624 639 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 690 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 601 623 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 647 670 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 808 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 738 749 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 835 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 701 726 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 760 771 9.2E-81 T 15-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05375 e069865fd5de50d738d266f3c3455c89 875 SMART SM00475 3 262 1.4E-152 T 15-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 SUPERFAMILY SSF55874 300 469 1.31E-41 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 306 4.3E-8 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 Gene3D G3DSA:3.30.565.10 317 472 7.4E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 SUPERFAMILY SSF47384 228 307 6.47E-14 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 2.7E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 2.7E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 2.7E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 2.7E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 Gene3D G3DSA:1.10.287.130 240 311 5.9E-15 T 15-10-2018 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 SUPERFAMILY SSF158472 184 234 3.14E-5 T 15-10-2018 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 469 4.9E-25 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 SMART SM00387 358 471 6.8E-37 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 SMART SM00388 244 311 2.7E-7 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_26090 20e281786397dd0ca772c00ba7da5dcc 473 Gene3D G3DSA:1.20.1480.50 161 239 8.3E-7 T 15-10-2018 C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 PIRSF PIRSF005485 1 340 1.6E-120 T 15-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 SUPERFAMILY SSF55781 71 339 8.63E-65 T 15-10-2018 C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 32.628 T 15-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 Gene3D G3DSA:3.30.390.60 128 229 9.4E-53 T 15-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 SUPERFAMILY SSF46785 2 84 5.45E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 335 5.4E-106 T 15-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 Gene3D G3DSA:3.30.450.40 104 336 9.4E-53 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 Gene3D G3DSA:1.10.10.10 1 84 9.1E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04390 de687a2c6db30ed75fbca49c2eade000 342 Pfam PF01628 HrcA protein C terminal domain 104 322 1.5E-60 T 15-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 402 1.3E-131 T 15-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 Gene3D G3DSA:3.40.50.720 200 407 4.0E-59 T 15-10-2018 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 PIRSF PIRSF500136 1 407 4.2E-149 T 15-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 SUPERFAMILY SSF52413 305 406 1.96E-22 T 15-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 406 1.2E-20 T 15-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 PIRSF PIRSF000124 3 407 9.3E-67 T 15-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 SMART SM00984 313 407 4.1E-27 T 15-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 180 1.9E-38 T 15-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 SUPERFAMILY SSF48179 200 293 3.74E-29 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 SUPERFAMILY SSF51735 3 194 5.09E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 Gene3D G3DSA:3.40.50.720 1 197 1.2E-58 T 15-10-2018 C2I28_00995 c23bc7bb04f772b047886401199a04fc 407 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 291 8.9E-29 T 15-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 Gene3D G3DSA:3.50.50.60 6 294 1.2E-59 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 SUPERFAMILY SSF51905 2 266 1.05E-42 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 7.1E-14 T 15-10-2018 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.1E-14 T 15-10-2018 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 7.1E-14 T 15-10-2018 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 7.1E-14 T 15-10-2018 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 7.1E-14 T 15-10-2018 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.2E-19 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 1.2E-19 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 1.2E-19 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 212 228 1.2E-19 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 1.2E-19 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 Gene3D G3DSA:3.50.50.60 132 249 1.2E-59 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 290 4.0E-108 T 15-10-2018 C2I28_03330 64bab4351ab132aaaaeab26f1f1119ac 323 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 319 7.3E-146 T 15-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:3.90.1800.10 1057 1110 1.1E-10 T 15-10-2018 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:2.40.50.100 672 751 3.4E-28 T 15-10-2018 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF04563 RNA polymerase beta subunit 28 454 4.2E-29 T 15-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:2.40.50.150 791 930 8.2E-61 T 15-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:2.40.270.10 981 1047 1.7E-24 T 15-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 896 0.0 T 15-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 SUPERFAMILY SSF64484 14 1155 0.0 T 15-10-2018 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 289 2.1E-28 T 15-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF04561 RNA polymerase Rpb2, domain 2 371 410 2.3E-6 T 15-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:3.90.1100.10 390 582 5.8E-75 T 15-10-2018 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1145 1.7E-27 T 15-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.611 T 15-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:2.40.270.10 752 790 4.3E-6 T 15-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 15-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:3.90.1100.10 20 153 1.3E-52 T 15-10-2018 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF00562 RNA polymerase Rpb2, domain 6 676 1069 7.1E-164 T 15-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:3.90.1100.10 606 671 5.0E-19 T 15-10-2018 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Gene3D G3DSA:3.90.1110.10 154 272 5.5E-9 T 15-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF04565 RNA polymerase Rpb2, domain 3 469 537 2.6E-30 T 15-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08645 c0de0b82b50b2e56dea6c62f1b19aa1c 1187 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 614 8.4E-24 T 15-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 226 346 1.0E-34 T 15-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 232 345 1.1E-5 T 15-10-2018 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 Gene3D G3DSA:3.40.50.150 201 398 3.3E-68 T 15-10-2018 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 SUPERFAMILY SSF53335 208 370 1.53E-24 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 60 185 1.1E-11 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 Gene3D G3DSA:3.40.1010.10 1 98 7.9E-14 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 SUPERFAMILY SSF53790 3 199 2.88E-32 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 PIRSF PIRSF036428 1 398 1.1E-125 T 15-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 C2I28_21190 cbab6e38c84a03c699083ef588b81090 398 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 5 196 1.1E-54 T 15-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 C2I28_18665 d36db65bab375f0a16cf07a2e392aec9 296 SUPERFAMILY SSF52540 46 278 2.53E-34 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18665 d36db65bab375f0a16cf07a2e392aec9 296 Gene3D G3DSA:3.40.50.300 42 213 4.7E-32 T 15-10-2018 C2I28_18665 d36db65bab375f0a16cf07a2e392aec9 296 Pfam PF07728 AAA domain (dynein-related subfamily) 59 196 2.1E-26 T 15-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I28_18665 d36db65bab375f0a16cf07a2e392aec9 296 SMART SM00382 56 206 2.6E-6 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 ProSitePatterns PS01047 Heavy-metal-associated domain. 92 121 - T 15-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Gene3D G3DSA:2.70.150.20 333 449 6.2E-35 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Gene3D G3DSA:3.40.1110.10 556 675 1.5E-88 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 295 847 1.5E-185 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 395 409 2.2E-25 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 559 2.2E-25 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 744 763 2.2E-25 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 691 701 2.2E-25 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 679 2.2E-25 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 768 780 2.2E-25 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 SUPERFAMILY SSF56784 544 845 9.22E-53 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 318 824 1.0E-89 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Pfam PF00403 Heavy-metal-associated domain 161 219 5.3E-13 T 15-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Pfam PF00403 Heavy-metal-associated domain 90 148 8.5E-11 T 15-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 SUPERFAMILY SSF81665 295 838 8.89E-19 T 15-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 90 99 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 259 276 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 430 444 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 173 194 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 411 427 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 350 366 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 PRINTS PR00941 Cadmium-transporting ATPase signature 330 350 2.4E-28 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 282 847 7.8E-123 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Pfam PF00122 E1-E2 ATPase 346 525 4.5E-56 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 296 597 2.7E-98 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Pfam PF00702 haloacid dehalogenase-like hydrolase 541 758 2.0E-43 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Gene3D G3DSA:3.30.70.100 85 161 8.1E-13 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 SUPERFAMILY SSF55008 154 225 1.28E-17 T 15-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Gene3D G3DSA:3.30.70.100 162 224 2.0E-17 T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 SUPERFAMILY SSF81653 348 445 1.18E-25 T 15-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 547 553 - T 15-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 Gene3D G3DSA:3.40.50.1000 526 796 1.5E-88 T 15-10-2018 IPR023214 HAD superfamily C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 ProSitePatterns PS01229 Hypothetical cof family signature 2. 744 766 - T 15-10-2018 C2I28_23790 fe56238e6fa15d57120a13fe04743a3a 852 SUPERFAMILY SSF55008 86 156 4.45E-13 T 15-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 Gene3D G3DSA:3.40.50.620 1 305 2.5E-136 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 Pfam PF09190 DALR domain 354 414 3.1E-16 T 15-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 2.6E-137 T 15-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 464 5.6E-192 T 15-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.2E-29 T 15-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 3.2E-29 T 15-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.2E-29 T 15-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 3.2E-29 T 15-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 SUPERFAMILY SSF47323 340 464 4.05E-32 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 SMART SM00840 353 416 3.5E-16 T 15-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.161 T 15-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 SUPERFAMILY SSF52374 3 313 1.93E-105 T 15-10-2018 C2I28_08580 eb1b449f5b459db1cae5aad4e609a971 465 Gene3D G3DSA:1.20.120.1910 306 465 6.4E-34 T 15-10-2018 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 Pfam PF00543 Nitrogen regulatory protein P-II 8 109 2.1E-32 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 PRINTS PR00340 P-II protein signature 27 45 4.8E-24 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 PRINTS PR00340 P-II protein signature 56 79 4.8E-24 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 PRINTS PR00340 P-II protein signature 6 21 4.8E-24 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 PRINTS PR00340 P-II protein signature 87 107 4.8E-24 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 SMART SM00938 8 109 5.1E-41 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 SUPERFAMILY SSF54913 6 118 2.57E-34 T 15-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta C2I28_22735 3bb772eacfa73a5332f471921799f744 120 ProSitePatterns PS00638 P-II protein C-terminal region signature. 87 100 - T 15-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 C2I28_22735 3bb772eacfa73a5332f471921799f744 120 Gene3D G3DSA:3.30.70.120 1 116 3.1E-41 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SMART SM00388 585 651 3.4E-24 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 791 804 2.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 732 746 2.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 750 760 2.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 PRINTS PR00344 Bacterial sensor protein C-terminal signature 767 785 2.5E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Gene3D G3DSA:1.20.1480.50 175 270 1.9E-11 T 15-10-2018 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SUPERFAMILY SSF55781 308 465 1.23E-11 T 15-10-2018 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Gene3D G3DSA:3.30.565.10 654 815 1.9E-48 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SMART SM00065 317 456 0.0064 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Gene3D G3DSA:3.30.450.40 273 455 1.7E-12 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Gene3D G3DSA:1.10.287.130 574 653 3.4E-27 T 15-10-2018 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SUPERFAMILY SSF55874 640 806 3.14E-47 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Pfam PF00989 PAS fold 464 576 3.0E-5 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Pfam PF00672 HAMP domain 215 261 2.5E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Gene3D G3DSA:3.30.450.20 456 573 7.0E-10 T 15-10-2018 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SMART SM00387 695 807 3.7E-42 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SUPERFAMILY SSF52172 823 943 8.54E-26 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 695 805 5.2E-30 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SMART SM00304 212 265 0.0017 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 464 581 1.0E-6 T 15-10-2018 IPR000014 PAS domain C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Pfam PF01590 GAF domain 319 446 4.6E-6 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SUPERFAMILY SSF158472 214 262 7.06E-6 T 15-10-2018 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SMART SM00448 824 936 1.1E-23 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Pfam PF00072 Response regulator receiver domain 826 936 1.8E-18 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SUPERFAMILY SSF55785 453 577 6.7E-8 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Gene3D G3DSA:3.40.50.12740 824 957 7.7E-27 T 15-10-2018 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 Pfam PF00512 His Kinase A (phospho-acceptor) domain 585 651 1.1E-21 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_12885 aa8ef674e172efcac19d98f41ccd4112 958 SUPERFAMILY SSF47384 571 652 5.1E-22 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_12850 aac8f321cb9935954177ea230f1ac362 244 SUPERFAMILY SSF51658 6 244 9.54E-41 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_12850 aac8f321cb9935954177ea230f1ac362 244 Gene3D G3DSA:3.20.20.150 1 244 9.5E-72 T 15-10-2018 C2I28_12850 aac8f321cb9935954177ea230f1ac362 244 Pfam PF01261 Xylose isomerase-like TIM barrel 25 203 1.5E-17 T 15-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 Gene3D G3DSA:3.40.1010.10 1 117 9.2E-45 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 15-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 4.8E-50 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 1.4E-102 T 15-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 SUPERFAMILY SSF53790 1 249 9.68E-85 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 Gene3D G3DSA:3.30.950.10 118 257 7.3E-52 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_06190 7237bbcccb96b19dc6a9396e461d4770 259 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 15-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 Gene3D G3DSA:1.10.10.60 132 181 4.4E-12 T 15-10-2018 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 215 231 5.0E-5 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 200 215 5.0E-5 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 Pfam PF12833 Helix-turn-helix domain 154 231 1.0E-20 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 SUPERFAMILY SSF51182 16 75 8.77E-7 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 185 227 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 Gene3D G3DSA:1.10.10.60 182 236 1.3E-17 T 15-10-2018 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 SMART SM00342 148 231 7.4E-30 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 SUPERFAMILY SSF46689 136 181 1.34E-8 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 Gene3D G3DSA:2.60.120.10 6 93 2.7E-7 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_19085 2059b30d39b5a2bb208b17ecc97c02cd 238 SUPERFAMILY SSF46689 184 232 1.04E-12 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 Gene3D G3DSA:3.90.226.10 1 209 2.1E-77 T 15-10-2018 C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 7.7E-91 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 56.861 T 15-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 Gene3D G3DSA:1.10.12.10 210 260 6.5E-29 T 15-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 1.1E-133 T 15-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 15-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I28_05995 129a0e2abff0f8bca15ae19db75b5a95 272 SUPERFAMILY SSF52096 4 268 3.42E-80 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 SUPERFAMILY SSF46689 355 467 8.24E-13 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 SUPERFAMILY SSF55785 4 116 4.57E-8 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Gene3D G3DSA:3.40.50.300 129 313 6.8E-60 T 15-10-2018 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 SUPERFAMILY SSF52540 142 384 7.35E-64 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Gene3D G3DSA:1.10.8.60 314 395 4.2E-22 T 15-10-2018 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Pfam PF00158 Sigma-54 interaction domain 143 308 1.4E-61 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Gene3D G3DSA:3.30.450.20 2 120 1.7E-12 T 15-10-2018 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 125 5.0E-9 T 15-10-2018 IPR000014 PAS domain C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Gene3D G3DSA:1.10.10.60 417 470 2.2E-13 T 15-10-2018 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Pfam PF02954 Bacterial regulatory protein, Fis family 427 465 4.0E-12 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 SMART SM00382 163 305 1.6E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 448 468 2.1E-9 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 448 2.1E-9 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 Pfam PF13426 PAS domain 22 121 4.7E-6 T 15-10-2018 IPR000014 PAS domain C2I28_11490 fa53fc8d51d5592a9dac586f160bd221 470 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_05100 895c35205f5b84cbada5b44dfd48cc42 205 Gene3D G3DSA:1.20.58.220 9 205 2.3E-54 T 15-10-2018 IPR038078 PhoU-like domain superfamily C2I28_05100 895c35205f5b84cbada5b44dfd48cc42 205 Pfam PF01865 Protein of unknown function DUF47 6 202 1.2E-23 T 15-10-2018 IPR018445 Putative phosphate transport regulator C2I28_05100 895c35205f5b84cbada5b44dfd48cc42 205 SUPERFAMILY SSF109755 6 196 1.09E-6 T 15-10-2018 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Gene3D G3DSA:3.30.300.10 13 284 2.4E-182 T 15-10-2018 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 1.1E-43 T 15-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Gene3D G3DSA:3.30.300.10 104 389 2.4E-182 T 15-10-2018 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 PIRSF PIRSF000497 1 398 5.9E-181 T 15-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 SUPERFAMILY SSF55973 247 395 1.73E-70 T 15-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 15-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Gene3D G3DSA:3.30.300.10 7 247 2.4E-182 T 15-10-2018 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 7.3E-189 T 15-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 5.3E-51 T 15-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 60.011 T 15-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 385 1.8E-70 T 15-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 SUPERFAMILY SSF55973 125 246 2.39E-54 T 15-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 SUPERFAMILY SSF55973 5 111 3.14E-47 T 15-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_05855 dd8c07f9edcbd5c81ad9dae54a528eb6 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 15-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 Gene3D G3DSA:3.40.605.10 17 515 9.0E-189 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 12 519 2.4E-258 T 15-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 Pfam PF00171 Aldehyde dehydrogenase family 56 517 3.6E-158 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 Gene3D G3DSA:3.40.309.10 297 487 9.0E-189 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 292 299 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 SUPERFAMILY SSF53720 10 518 4.97E-154 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_00730 9e0da951c41df0bb88e7f6b330d5a4a8 522 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 8 522 68.149 T 15-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 109 2.9E-12 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 SUPERFAMILY SSF56645 22 212 3.66E-34 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 233 367 5.8E-17 T 15-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 SUPERFAMILY SSF47203 230 387 2.09E-20 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 Gene3D G3DSA:1.10.540.10 11 117 6.8E-25 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 PIRSF PIRSF016578 1 388 5.3E-33 T 15-10-2018 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 Gene3D G3DSA:2.40.110.10 118 212 8.8E-23 T 15-10-2018 C2I28_12530 96742bd29fec1fdff8c3c0075a7ce2e2 393 Gene3D G3DSA:1.20.140.10 213 392 3.8E-57 T 15-10-2018 C2I28_11940 8df27243d943475cad39e1d30f41a7a5 281 Pfam PF01380 SIS domain 126 255 8.0E-22 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_11940 8df27243d943475cad39e1d30f41a7a5 281 Gene3D G3DSA:1.10.10.10 1 83 1.1E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11940 8df27243d943475cad39e1d30f41a7a5 281 SUPERFAMILY SSF53697 94 278 1.7E-46 T 15-10-2018 C2I28_11940 8df27243d943475cad39e1d30f41a7a5 281 SUPERFAMILY SSF46689 2 79 1.34E-22 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_11940 8df27243d943475cad39e1d30f41a7a5 281 Gene3D G3DSA:3.40.50.10490 94 280 3.8E-52 T 15-10-2018 C2I28_11940 8df27243d943475cad39e1d30f41a7a5 281 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 76 9.7E-25 T 15-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.7E-35 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 Gene3D G3DSA:4.10.520.10 1 90 8.8E-38 T 15-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 8.8E-19 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 8.8E-19 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 8.8E-19 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 SMART SM00411 1 90 3.0E-43 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_26810 7cf17d769cbb2fc7d2b6f580889e83ab 90 SUPERFAMILY SSF47729 1 90 4.56E-33 T 15-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I28_04860 23ef93dca064b1ac76d6d11665a4fb3a 489 Pfam PF10150 Ribonuclease E/G family 124 383 6.6E-81 T 15-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 C2I28_04860 23ef93dca064b1ac76d6d11665a4fb3a 489 SUPERFAMILY SSF50249 40 118 3.33E-16 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_04860 23ef93dca064b1ac76d6d11665a4fb3a 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 16 416 2.9E-115 T 15-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 C2I28_04860 23ef93dca064b1ac76d6d11665a4fb3a 489 SMART SM00316 38 119 2.2E-7 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_04860 23ef93dca064b1ac76d6d11665a4fb3a 489 Pfam PF00575 S1 RNA binding domain 39 104 1.6E-4 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_04860 23ef93dca064b1ac76d6d11665a4fb3a 489 Gene3D G3DSA:2.40.50.140 32 124 3.7E-25 T 15-10-2018 C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 Gene3D G3DSA:3.40.50.1100 9 321 7.8E-126 T 15-10-2018 C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 Gene3D G3DSA:3.40.50.1100 58 154 7.8E-126 T 15-10-2018 C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 SUPERFAMILY SSF53686 6 349 1.13E-108 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 PIRSF PIRSF038945 1 347 1.8E-158 T 15-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 15-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 TIGRFAM TIGR00260 thrC: threonine synthase 8 322 2.8E-105 T 15-10-2018 IPR004450 Threonine synthase-like C2I28_06430 a0e32f6838f956a448314ff4e088ad32 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 1.4E-77 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 SUPERFAMILY SSF55347 151 315 4.51E-53 T 15-10-2018 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 SMART SM00859 5 143 7.3E-53 T 15-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 318 1.5E-27 T 15-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 5 347 1.3E-138 T 15-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 4 341 43.586 T 15-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 SUPERFAMILY SSF51735 2 178 3.44E-50 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 141 1.4E-34 T 15-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 Gene3D G3DSA:3.40.50.720 5 333 8.4E-132 T 15-10-2018 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 146 162 - T 15-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_11545 04399106805a03ac88c7bccaca4ef971 347 Gene3D G3DSA:3.30.360.10 149 315 8.4E-132 T 15-10-2018 C2I28_07995 21e094e4311573f29f16847c550c162f 209 Gene3D G3DSA:3.30.1370.50 141 209 1.5E-23 T 15-10-2018 IPR036867 R3H domain superfamily GO:0003676 C2I28_07995 21e094e4311573f29f16847c550c162f 209 SMART SM01245 5 57 3.4E-19 T 15-10-2018 IPR032782 Jag, N-terminal C2I28_07995 21e094e4311573f29f16847c550c162f 209 Pfam PF01424 R3H domain 144 202 5.2E-16 T 15-10-2018 IPR001374 R3H domain GO:0003676 C2I28_07995 21e094e4311573f29f16847c550c162f 209 Pfam PF13083 KH domain 66 128 8.0E-14 T 15-10-2018 C2I28_07995 21e094e4311573f29f16847c550c162f 209 SUPERFAMILY SSF82708 147 204 1.94E-8 T 15-10-2018 IPR036867 R3H domain superfamily GO:0003676 C2I28_07995 21e094e4311573f29f16847c550c162f 209 SMART SM00393 126 205 1.8E-22 T 15-10-2018 IPR001374 R3H domain GO:0003676 C2I28_07995 21e094e4311573f29f16847c550c162f 209 Pfam PF14804 Jag N-terminus 6 55 9.2E-18 T 15-10-2018 IPR032782 Jag, N-terminal C2I28_07995 21e094e4311573f29f16847c550c162f 209 Gene3D G3DSA:3.30.30.80 1 56 1.4E-17 T 15-10-2018 IPR038247 Jag, N-terminal domain superfamily C2I28_07995 21e094e4311573f29f16847c550c162f 209 Gene3D G3DSA:3.30.300.20 59 140 9.6E-24 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 Gene3D G3DSA:1.10.10.10 1 88 2.4E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.6E-17 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 SUPERFAMILY SSF46785 3 110 4.3E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.8E-7 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.8E-7 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.8E-7 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 SUPERFAMILY SSF53850 90 287 3.77E-34 T 15-10-2018 C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 Pfam PF03466 LysR substrate binding domain 89 285 1.1E-35 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_24660 2e54cfa88206a9aa3a96bad184713207 290 Gene3D G3DSA:3.40.190.290 90 288 6.6E-43 T 15-10-2018 C2I28_21725 8ad6aaf5733216628ad5e41eabe4ef8d 221 SUPERFAMILY SSF51182 27 179 1.33E-31 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_21725 8ad6aaf5733216628ad5e41eabe4ef8d 221 SMART SM00835 17 159 5.5E-22 T 15-10-2018 IPR006045 Cupin 1 GO:0045735 C2I28_21725 8ad6aaf5733216628ad5e41eabe4ef8d 221 Pfam PF00190 Cupin 40 157 5.3E-15 T 15-10-2018 IPR006045 Cupin 1 GO:0045735 C2I28_21725 8ad6aaf5733216628ad5e41eabe4ef8d 221 Gene3D G3DSA:2.60.120.10 30 200 1.3E-27 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 SMART SM01002 143 291 2.9E-41 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 SUPERFAMILY SSF52283 1 349 2.89E-35 T 15-10-2018 C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 Gene3D G3DSA:3.40.50.720 124 299 2.0E-103 T 15-10-2018 C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 SMART SM01003 4 131 1.4E-30 T 15-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 Gene3D G3DSA:3.40.50.720 4 347 2.0E-103 T 15-10-2018 C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 118 3.7E-31 T 15-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 137 347 2.0E-50 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_00310 6099f9986e23e2b66d6e91d5e74dcc1c 388 SUPERFAMILY SSF51735 131 297 5.0E-34 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 SUPERFAMILY SSF53383 78 455 6.25E-127 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 Gene3D G3DSA:3.40.640.10 106 356 1.4E-182 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 Pfam PF00202 Aminotransferase class-III 76 452 1.5E-107 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 Gene3D G3DSA:3.90.1150.10 41 451 1.4E-182 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 PIRSF PIRSF000521 30 176 6.2E-6 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 PIRSF PIRSF000521 171 208 2.9 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 PIRSF PIRSF000521 217 455 1.0E-41 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12505 d9e4feae0a880e593d0e46d36984d470 458 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 271 308 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01985 abc21edd2176f294f280fd72b85e4560 70 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 5 39 6.0E-12 T 15-10-2018 IPR005359 Protein with unknown function UPF0154 C2I28_01985 abc21edd2176f294f280fd72b85e4560 70 Hamap MF_00363 UPF0154 protein . 2 70 19.855 T 15-10-2018 IPR005359 Protein with unknown function UPF0154 C2I28_01985 abc21edd2176f294f280fd72b85e4560 70 Pfam PF03672 Uncharacterised protein family (UPF0154) 9 66 6.2E-30 T 15-10-2018 IPR005359 Protein with unknown function UPF0154 C2I28_07405 853c46ca424fd7997cf6d66c4c4635b5 148 Gene3D G3DSA:3.40.630.30 2 134 1.2E-11 T 15-10-2018 C2I28_07405 853c46ca424fd7997cf6d66c4c4635b5 148 SUPERFAMILY SSF55729 1 134 1.11E-6 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 Gene3D G3DSA:3.90.230.10 125 352 9.4E-86 T 15-10-2018 C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 SUPERFAMILY SSF53092 2 124 4.76E-24 T 15-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 126 4.4E-26 T 15-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 282 294 - T 15-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 PRINTS PR00599 Methionine aminopeptidase-1 signature 304 316 1.1E-5 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 PRINTS PR00599 Methionine aminopeptidase-1 signature 206 222 1.1E-5 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 SUPERFAMILY SSF55920 82 346 1.27E-82 T 15-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 Pfam PF00557 Metallopeptidase family M24 135 336 2.8E-68 T 15-10-2018 IPR000994 Peptidase M24 C2I28_03925 ec880ad613cab4f34a1dd30482ecb268 352 Gene3D G3DSA:3.40.350.10 1 124 2.9E-37 T 15-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I28_26700 de6d9c4122dd557a2263e2523d732d58 210 Pfam PF00005 ABC transporter 19 159 1.4E-30 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_26700 de6d9c4122dd557a2263e2523d732d58 210 SUPERFAMILY SSF52540 3 206 5.54E-52 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26700 de6d9c4122dd557a2263e2523d732d58 210 SMART SM00382 28 205 9.0E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_26700 de6d9c4122dd557a2263e2523d732d58 210 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_26700 de6d9c4122dd557a2263e2523d732d58 210 Gene3D G3DSA:3.40.50.300 1 210 4.0E-54 T 15-10-2018 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 SUPERFAMILY SSF53335 3 278 3.73E-49 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 2 281 3.9E-78 T 15-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 Gene3D G3DSA:3.40.50.150 84 282 3.5E-62 T 15-10-2018 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 Gene3D G3DSA:1.10.8.10 1 83 3.0E-18 T 15-10-2018 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 280 40.871 T 15-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 276 1.4E-83 T 15-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 Pfam PF05175 Methyltransferase small domain 103 193 2.8E-15 T 15-10-2018 IPR007848 Methyltransferase small domain GO:0008168 C2I28_07415 cd061933cb6de5a7321c53ccb271ff5b 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 15-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 Gene3D G3DSA:3.40.50.620 1 332 2.4E-144 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 SUPERFAMILY SSF48163 298 482 3.53E-49 T 15-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 34.483 T 15-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 SUPERFAMILY SSF52374 5 316 4.83E-116 T 15-10-2018 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 2.7E-126 T 15-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 Gene3D G3DSA:1.10.10.350 390 485 1.7E-33 T 15-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 481 1.0E-194 T 15-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 6.1E-29 T 15-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 6.1E-29 T 15-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 6.1E-29 T 15-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 6.1E-29 T 15-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I28_08570 c9e89d3681eee65be5d04005f358bf70 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 6.1E-29 T 15-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 C2I28_01825 e35ce9feac544e94715c4c5c88e3fde5 192 Gene3D G3DSA:3.40.30.10 23 191 1.4E-56 T 15-10-2018 C2I28_01825 e35ce9feac544e94715c4c5c88e3fde5 192 SUPERFAMILY SSF52833 30 191 2.28E-42 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_01825 e35ce9feac544e94715c4c5c88e3fde5 192 Pfam PF02630 SCO1/SenC 14 174 3.8E-41 T 15-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 SUPERFAMILY SSF46785 180 247 6.26E-7 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 PRINTS PR00502 NUDIX hydrolase family signature 68 82 7.9E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 PRINTS PR00502 NUDIX hydrolase family signature 82 97 7.9E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 Gene3D G3DSA:3.90.79.10 17 182 1.0E-51 T 15-10-2018 C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 Pfam PF00293 NUDIX domain 47 165 1.0E-14 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 SUPERFAMILY SSF55811 46 180 8.53E-26 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 Gene3D G3DSA:1.10.10.10 183 251 1.5E-9 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19025 9b9a2badbc8fae681e45e08a3ee92084 258 ProSitePatterns PS00893 Nudix box signature. 73 94 - T 15-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 3.2E-58 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Gene3D G3DSA:3.40.50.620 32 571 4.5E-281 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Gene3D G3DSA:3.10.20.590 744 803 4.1E-23 T 15-10-2018 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Gene3D G3DSA:1.10.730.10 599 740 4.0E-47 T 15-10-2018 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 4.0E-20 T 15-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Gene3D G3DSA:3.90.740.10 226 410 4.5E-281 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 SUPERFAMILY SSF50677 224 410 5.44E-55 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.395 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 SUPERFAMILY SSF52374 2 625 2.0E-148 T 15-10-2018 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.5E-17 T 15-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 803 0.0 T 15-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Gene3D G3DSA:2.30.210.10 572 588 4.5E-281 T 15-10-2018 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 SUPERFAMILY SSF47323 619 803 1.85E-41 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Pfam PF08264 Anticodon-binding domain of tRNA 652 764 2.3E-21 T 15-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I28_05795 36ea59feefb2ec3a3a2495d8fee30f6f 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 398 8.2E-70 T 15-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 Gene3D G3DSA:3.40.309.10 250 429 7.2E-153 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 Gene3D G3DSA:3.40.605.10 430 478 1.0E-5 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 Pfam PF00171 Aldehyde dehydrogenase family 13 470 2.5E-158 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 SUPERFAMILY SSF53720 3 471 1.18E-151 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 Gene3D G3DSA:3.40.605.10 11 249 7.2E-153 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_15820 5c433b0810735058f4339d4e0a6aba7f 479 PIRSF PIRSF036492 22 478 1.9E-83 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_17300 27c053cd243194800ce0e25823807f07 312 Gene3D G3DSA:2.60.40.420 111 274 8.0E-47 T 15-10-2018 IPR008972 Cupredoxin C2I28_17300 27c053cd243194800ce0e25823807f07 312 SUPERFAMILY SSF81464 13 112 2.13E-19 T 15-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17300 27c053cd243194800ce0e25823807f07 312 SUPERFAMILY SSF49503 119 252 7.79E-44 T 15-10-2018 IPR008972 Cupredoxin C2I28_17300 27c053cd243194800ce0e25823807f07 312 Gene3D G3DSA:1.10.287.90 25 110 1.6E-30 T 15-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17300 27c053cd243194800ce0e25823807f07 312 PIRSF PIRSF000292 1 309 6.9E-106 T 15-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 C2I28_17300 27c053cd243194800ce0e25823807f07 312 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 42 103 5.9E-5 T 15-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17300 27c053cd243194800ce0e25823807f07 312 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 145 220 2.6E-6 T 15-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_16065 c371b325efa006487fe4b507c41367b6 190 Gene3D G3DSA:3.40.630.30 5 188 4.9E-47 T 15-10-2018 C2I28_16065 c371b325efa006487fe4b507c41367b6 190 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 2.4E-30 T 15-10-2018 IPR000182 GNAT domain C2I28_16065 c371b325efa006487fe4b507c41367b6 190 SUPERFAMILY SSF55729 4 177 3.42E-48 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 555 4.7E-216 T 15-10-2018 IPR019986 DAK2 domain-containing protein YloV C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 Pfam PF13684 Dihydroxyacetone kinase family 240 555 4.9E-127 T 15-10-2018 IPR033470 Uncharacterised protein, DhaK domain C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 SMART SM01121 240 555 2.6E-192 T 15-10-2018 IPR033470 Uncharacterised protein, DhaK domain C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 Gene3D G3DSA:1.25.40.340 4 197 2.1E-10 T 15-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 SUPERFAMILY SSF101473 2 200 1.03E-46 T 15-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 SMART SM01120 36 201 6.5E-70 T 15-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_02710 7a4fcc894725045ed070ded95bf68950 555 Pfam PF02734 DAK2 domain 36 200 1.2E-41 T 15-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_07565 128eb7422975ce67b133a61ffe41d784 435 Gene3D G3DSA:1.20.1250.30 235 412 1.1E-169 T 15-10-2018 C2I28_07565 128eb7422975ce67b133a61ffe41d784 435 SMART SM00471 57 187 3.4E-13 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_07565 128eb7422975ce67b133a61ffe41d784 435 Pfam PF01966 HD domain 61 181 8.5E-17 T 15-10-2018 IPR006674 HD domain C2I28_07565 128eb7422975ce67b133a61ffe41d784 435 Gene3D G3DSA:1.10.3210.10 11 401 1.1E-169 T 15-10-2018 C2I28_07565 128eb7422975ce67b133a61ffe41d784 435 SUPERFAMILY SSF109604 5 418 7.33E-122 T 15-10-2018 C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 175 2.7E-25 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 SUPERFAMILY SSF88659 115 177 5.98E-14 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 Gene3D G3DSA:1.10.1740.10 3 117 5.0E-24 T 15-10-2018 C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 Gene3D G3DSA:1.10.10.10 118 177 4.3E-14 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 Pfam PF04542 Sigma-70 region 2 23 84 2.4E-15 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 Pfam PF08281 Sigma-70, region 4 120 169 1.2E-10 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_25125 09b6e02de61d9e1d24c383e1fb187c5b 177 SUPERFAMILY SSF88946 12 99 1.18E-21 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_24530 c3c6049d304c3b613c8d4d79a1171229 154 SUPERFAMILY SSF48452 24 132 8.04E-8 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_24530 c3c6049d304c3b613c8d4d79a1171229 154 Gene3D G3DSA:1.25.40.10 19 151 4.9E-7 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_22250 a940d5f7471229b74f602f61204e6ca4 149 SUPERFAMILY SSF55729 13 137 1.33E-17 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22250 a940d5f7471229b74f602f61204e6ca4 149 Gene3D G3DSA:3.40.630.30 1 147 7.4E-32 T 15-10-2018 C2I28_22250 a940d5f7471229b74f602f61204e6ca4 149 Pfam PF13673 Acetyltransferase (GNAT) domain 36 134 1.6E-13 T 15-10-2018 IPR000182 GNAT domain C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 SUPERFAMILY SSF56645 22 262 9.82E-72 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Gene3D G3DSA:2.40.110.10 145 250 2.1E-123 T 15-10-2018 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Gene3D G3DSA:1.10.540.10 34 144 2.1E-123 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 SUPERFAMILY SSF47203 250 419 5.96E-41 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Gene3D G3DSA:1.20.140.10 251 411 2.1E-123 T 15-10-2018 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 239 6.2E-21 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 412 8.7E-34 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 142 7.3E-30 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 Gene3D G3DSA:1.20.140.10 420 592 1.5E-33 T 15-10-2018 C2I28_19870 a630c928bc6b8b60fcb16d06c3045ab9 592 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_08760 197e821986896116a81cf9125afe29ff 179 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.8E-34 T 15-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_08760 197e821986896116a81cf9125afe29ff 179 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.8E-34 T 15-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_08760 197e821986896116a81cf9125afe29ff 179 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.8E-34 T 15-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_08760 197e821986896116a81cf9125afe29ff 179 Gene3D G3DSA:3.90.930.12 83 178 5.2E-41 T 15-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08760 197e821986896116a81cf9125afe29ff 179 Pfam PF00347 Ribosomal protein L6 90 164 2.2E-21 T 15-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08760 197e821986896116a81cf9125afe29ff 179 Pfam PF00347 Ribosomal protein L6 12 82 2.1E-23 T 15-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08760 197e821986896116a81cf9125afe29ff 179 SUPERFAMILY SSF56053 83 176 3.74E-35 T 15-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08760 197e821986896116a81cf9125afe29ff 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 39.954 T 15-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_08760 197e821986896116a81cf9125afe29ff 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 15-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08760 197e821986896116a81cf9125afe29ff 179 Gene3D G3DSA:3.90.930.12 1 82 1.6E-33 T 15-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08760 197e821986896116a81cf9125afe29ff 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.0E-78 T 15-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_08760 197e821986896116a81cf9125afe29ff 179 SUPERFAMILY SSF56053 1 82 2.4E-29 T 15-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08760 197e821986896116a81cf9125afe29ff 179 PIRSF PIRSF002162 1 177 7.3E-52 T 15-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 SUPERFAMILY SSF53383 8 426 1.08E-126 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 Gene3D G3DSA:3.40.640.10 8 290 2.3E-102 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 425 5.5E-208 T 15-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 426 4.4E-147 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 Gene3D G3DSA:3.90.1150.10 294 435 1.4E-53 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 PIRSF PIRSF001434 1 429 2.6E-130 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_12265 43a77fc659a24e41c5231864164fd13c 435 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 Pfam PF12836 Helix-hairpin-helix motif 147 209 4.3E-23 T 15-10-2018 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 SUPERFAMILY SSF47781 139 210 5.89E-30 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 Gene3D G3DSA:1.10.150.310 154 211 4.1E-14 T 15-10-2018 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 Pfam PF10531 SLBB domain 68 116 5.1E-14 T 15-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 SMART SM00278 158 177 0.4 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 SMART SM00278 188 207 110.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 Gene3D G3DSA:3.10.560.10 55 153 6.5E-11 T 15-10-2018 C2I28_04440 83deab061f919da1956891ddbd2f8ea8 211 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 148 210 1.4E-28 T 15-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain C2I28_15595 13ab36bc13521be9173419b83adfa460 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 3.4E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15595 13ab36bc13521be9173419b83adfa460 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 3.4E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15595 13ab36bc13521be9173419b83adfa460 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 3.4E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15595 13ab36bc13521be9173419b83adfa460 153 SUPERFAMILY SSF46785 17 146 6.62E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15595 13ab36bc13521be9173419b83adfa460 153 Gene3D G3DSA:1.10.10.10 1 148 3.2E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_15595 13ab36bc13521be9173419b83adfa460 153 SMART SM00347 31 131 1.3E-20 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15595 13ab36bc13521be9173419b83adfa460 153 Pfam PF01047 MarR family 38 96 2.9E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_24415 558ce7e3fa8efecb04bff0c3f18045f1 308 TIGRFAM TIGR02640 gas_vesic_GvpN: gas vesicle protein GvpN 15 278 1.4E-132 T 15-10-2018 IPR013462 Gas vesicle protein GvpN GO:0000166|GO:0005524|GO:0031411|GO:0031412 C2I28_24415 558ce7e3fa8efecb04bff0c3f18045f1 308 SMART SM00382 34 202 6.8E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_24415 558ce7e3fa8efecb04bff0c3f18045f1 308 SUPERFAMILY SSF52540 15 289 3.34E-32 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_24415 558ce7e3fa8efecb04bff0c3f18045f1 308 Pfam PF07728 AAA domain (dynein-related subfamily) 40 191 6.1E-15 T 15-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I28_24415 558ce7e3fa8efecb04bff0c3f18045f1 308 Gene3D G3DSA:3.40.50.300 20 209 2.4E-28 T 15-10-2018 C2I28_00245 bce81e901596812f2bacac8a1395ba27 169 SUPERFAMILY SSF55729 2 163 5.59E-40 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_00245 bce81e901596812f2bacac8a1395ba27 169 Gene3D G3DSA:3.40.630.30 1 169 3.3E-46 T 15-10-2018 C2I28_00245 bce81e901596812f2bacac8a1395ba27 169 Pfam PF13302 Acetyltransferase (GNAT) domain 5 138 7.1E-20 T 15-10-2018 IPR000182 GNAT domain C2I28_06300 1afc64211805211407f0f34a067c1365 166 SMART SM00344 3 114 1.6E-5 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_06300 1afc64211805211407f0f34a067c1365 166 Gene3D G3DSA:3.30.70.920 55 153 1.6E-19 T 15-10-2018 C2I28_06300 1afc64211805211407f0f34a067c1365 166 Gene3D G3DSA:1.10.10.10 3 54 4.0E-10 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06300 1afc64211805211407f0f34a067c1365 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 1.3E-7 T 15-10-2018 C2I28_06300 1afc64211805211407f0f34a067c1365 166 SUPERFAMILY SSF46785 3 60 2.54E-7 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_06300 1afc64211805211407f0f34a067c1365 166 SUPERFAMILY SSF54909 66 147 3.62E-17 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_06300 1afc64211805211407f0f34a067c1365 166 Pfam PF01037 Lrp/AsnC ligand binding domain 72 144 2.1E-13 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_16235 70fb9a79fc940942bb16bf842fb33acc 198 ProDom PD207074 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED RC1356 RP875 39 128 0.001 T 15-10-2018 C2I28_16235 70fb9a79fc940942bb16bf842fb33acc 198 Gene3D G3DSA:3.40.50.620 60 151 2.3E-6 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_16235 70fb9a79fc940942bb16bf842fb33acc 198 Pfam PF02698 DUF218 domain 40 163 5.0E-23 T 15-10-2018 IPR003848 Domain of unknown function DUF218 C2I28_02170 c1f29328b4107ff8c99909f2ed962468 194 Gene3D G3DSA:1.20.120.1760 3 181 1.4E-8 T 15-10-2018 C2I28_02170 c1f29328b4107ff8c99909f2ed962468 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 15-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I28_02170 c1f29328b4107ff8c99909f2ed962468 194 PIRSF PIRSF000847 1 194 1.8E-48 T 15-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 C2I28_02170 c1f29328b4107ff8c99909f2ed962468 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 1.7E-17 T 15-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I28_02170 c1f29328b4107ff8c99909f2ed962468 194 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 190 3.9E-60 T 15-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 26 254 5.1E-74 T 15-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 SUPERFAMILY SSF56601 1 270 1.14E-68 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 Gene3D G3DSA:3.40.710.10 31 270 2.4E-88 T 15-10-2018 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 271 358 5.9E-5 T 15-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 134 147 1.4E-16 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 1.4E-16 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 1.4E-16 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_03440 6d67b1bbfc2e57d02f4752771e08afd8 382 Gene3D G3DSA:2.30.140.30 271 361 5.5E-28 T 15-10-2018 C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.7E-51 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.7E-51 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.7E-51 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.7E-51 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.7E-51 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.7E-51 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 1.0E-109 T 15-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_02670 698880000f43d404342361a061c05bcc 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 7.2E-71 T 15-10-2018 C2I28_02670 698880000f43d404342361a061c05bcc 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_02670 698880000f43d404342361a061c05bcc 246 SUPERFAMILY SSF51735 3 246 1.27E-94 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_02670 698880000f43d404342361a061c05bcc 246 Gene3D G3DSA:3.40.50.720 1 246 2.6E-92 T 15-10-2018 C2I28_02670 698880000f43d404342361a061c05bcc 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 1.6E-5 T 15-10-2018 C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.4E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.4E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02670 698880000f43d404342361a061c05bcc 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.4E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24540 084ecc2744d451666abdd4b94a6252f0 442 PIRSF PIRSF000337 3 436 7.3E-139 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_24540 084ecc2744d451666abdd4b94a6252f0 442 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 421 2.2E-154 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_24540 084ecc2744d451666abdd4b94a6252f0 442 SUPERFAMILY SSF51679 4 427 1.19E-122 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_24540 084ecc2744d451666abdd4b94a6252f0 442 Pfam PF00296 Luciferase-like monooxygenase 23 376 1.5E-56 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_19280 fc7556422653422ee1e319297a1182ce 381 SUPERFAMILY SSF51604 100 369 1.7E-71 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_19280 fc7556422653422ee1e319297a1182ce 381 Gene3D G3DSA:3.20.20.120 109 369 1.0E-81 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_19280 fc7556422653422ee1e319297a1182ce 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 112 4.0E-7 T 15-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I28_19280 fc7556422653422ee1e319297a1182ce 381 Pfam PF13378 Enolase C-terminal domain-like 134 361 4.1E-64 T 15-10-2018 IPR029065 Enolase C-terminal domain-like C2I28_19280 fc7556422653422ee1e319297a1182ce 381 SMART SM00922 130 237 4.6E-21 T 15-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I28_19280 fc7556422653422ee1e319297a1182ce 381 SUPERFAMILY SSF54826 1 112 2.53E-19 T 15-10-2018 C2I28_19280 fc7556422653422ee1e319297a1182ce 381 Gene3D G3DSA:3.30.390.10 1 108 8.8E-20 T 15-10-2018 IPR029017 Enolase-like, N-terminal C2I28_03595 85ce0d98026e22b643fd764174a6717a 229 SUPERFAMILY SSF100950 2 223 1.88E-89 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_03595 85ce0d98026e22b643fd764174a6717a 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 3 214 1.3E-80 T 15-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 C2I28_03595 85ce0d98026e22b643fd764174a6717a 229 Pfam PF01144 Coenzyme A transferase 7 213 1.8E-77 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_03595 85ce0d98026e22b643fd764174a6717a 229 Gene3D G3DSA:3.40.1080.10 1 225 4.7E-98 T 15-10-2018 C2I28_03595 85ce0d98026e22b643fd764174a6717a 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 15-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 C2I28_03595 85ce0d98026e22b643fd764174a6717a 229 SMART SM00882 5 216 4.4E-90 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Gene3D G3DSA:3.40.50.10990 205 374 1.1E-78 T 15-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 55.453 T 15-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.499 T 15-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 37.951 T 15-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 PIRSF PIRSF001259 1 397 1.3E-188 T 15-10-2018 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Gene3D G3DSA:3.90.870.10 1 204 5.5E-86 T 15-10-2018 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 3.7E-82 T 15-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 SUPERFAMILY SSF142695 203 374 1.19E-74 T 15-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 SUPERFAMILY SSF55821 2 201 1.42E-83 T 15-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 208 395 9.4E-83 T 15-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 8.2E-79 T 15-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14530 d815b9c526d6734d7718f2ac67c4452a 397 Pfam PF00925 GTP cyclohydrolase II 206 371 4.3E-78 T 15-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_18035 67345b3f4595ccf5e1682ddc4ab48818 317 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 66 1.3E-16 T 15-10-2018 C2I28_18035 67345b3f4595ccf5e1682ddc4ab48818 317 SUPERFAMILY SSF51905 1 314 1.07E-32 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18035 67345b3f4595ccf5e1682ddc4ab48818 317 Gene3D G3DSA:3.50.50.60 4 310 1.7E-72 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18035 67345b3f4595ccf5e1682ddc4ab48818 317 Gene3D G3DSA:3.90.660.10 42 269 1.7E-72 T 15-10-2018 C2I28_18035 67345b3f4595ccf5e1682ddc4ab48818 317 Pfam PF01593 Flavin containing amine oxidoreductase 91 312 4.8E-11 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 SMART SM00287 111 172 3.8E-16 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 SMART SM00287 41 102 3.7E-11 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 SMART SM00287 185 246 5.8E-16 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 SUPERFAMILY SSF50044 66 109 2.85E-5 T 15-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Pfam PF08239 Bacterial SH3 domain 193 243 6.7E-16 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Pfam PF08239 Bacterial SH3 domain 119 169 1.7E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Pfam PF08239 Bacterial SH3 domain 50 99 7.4E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 SUPERFAMILY SSF50044 136 185 4.21E-6 T 15-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Gene3D G3DSA:2.30.30.40 178 247 1.2E-21 T 15-10-2018 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Gene3D G3DSA:2.30.30.40 105 172 2.5E-21 T 15-10-2018 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Pfam PF03734 L,D-transpeptidase catalytic domain 295 438 8.5E-6 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 Gene3D G3DSA:2.30.30.40 40 104 6.4E-19 T 15-10-2018 C2I28_09010 6d3d55819e21c21a5a1c59a3a0a93da0 448 SUPERFAMILY SSF50044 210 249 1.26E-5 T 15-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 Gene3D G3DSA:3.30.1340.20 74 180 8.7E-35 T 15-10-2018 IPR035922 3H domain superfamily C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 SUPERFAMILY SSF46785 9 68 3.72E-11 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 Pfam PF08279 HTH domain 13 66 7.5E-15 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 84 178 2.0E-31 T 15-10-2018 IPR004173 3H domain GO:0036094 C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 Gene3D G3DSA:1.10.10.10 3 68 6.7E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 Pfam PF02829 3H domain 81 177 1.8E-33 T 15-10-2018 IPR004173 3H domain GO:0036094 C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 PIRSF PIRSF037847 8 180 5.8E-66 T 15-10-2018 IPR026043 Transcription repressor NadR C2I28_04820 1b4bde372766a35708b05b3e7f00b804 181 SUPERFAMILY SSF75500 77 179 4.84E-35 T 15-10-2018 IPR035922 3H domain superfamily C2I28_27015 f8f3493ae7858f97cd62a347ed7c41e7 282 Gene3D G3DSA:3.60.15.10 30 278 4.2E-73 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_27015 f8f3493ae7858f97cd62a347ed7c41e7 282 SUPERFAMILY SSF56281 30 279 3.22E-52 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_27015 f8f3493ae7858f97cd62a347ed7c41e7 282 SMART SM00849 42 237 8.4E-9 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_27015 f8f3493ae7858f97cd62a347ed7c41e7 282 Pfam PF00753 Metallo-beta-lactamase superfamily 40 236 6.5E-17 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 10 457 2.1E-149 T 15-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Gene3D G3DSA:3.40.50.300 203 334 2.8E-40 T 15-10-2018 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SMART SM00490 244 325 4.6E-26 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Pfam PF00271 Helicase conserved C-terminal domain 217 324 2.2E-19 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Gene3D G3DSA:3.40.50.300 2 202 1.0E-76 T 15-10-2018 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Gene3D G3DSA:1.10.10.10 335 512 6.5E-44 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SMART SM00341 514 594 8.2E-17 T 15-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SUPERFAMILY SSF52540 59 347 1.9E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Gene3D G3DSA:1.10.150.80 513 593 1.4E-24 T 15-10-2018 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Pfam PF16124 RecQ zinc-binding 336 398 6.7E-18 T 15-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SMART SM00487 15 212 1.0E-27 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Pfam PF14493 Helix-turn-helix domain 614 702 2.6E-30 T 15-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Pfam PF00270 DEAD/DEAH box helicase 22 182 6.9E-19 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 9 586 2.1E-237 T 15-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SUPERFAMILY SSF46785 397 539 3.81E-33 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Pfam PF09382 RQC domain 404 510 6.0E-30 T 15-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SMART SM00956 406 509 1.0E-39 T 15-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 SUPERFAMILY SSF47819 517 591 1.11E-24 T 15-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 C2I28_19355 b0323bde595c0efd34727ecdd9d97272 711 Pfam PF00570 HRDC domain 518 583 3.5E-20 T 15-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 C2I28_03345 1631147c471280b3f2f371aca9149828 303 Gene3D G3DSA:1.10.1660.10 1 94 4.1E-23 T 15-10-2018 C2I28_03345 1631147c471280b3f2f371aca9149828 303 Gene3D G3DSA:3.40.50.280 177 283 1.4E-15 T 15-10-2018 C2I28_03345 1631147c471280b3f2f371aca9149828 303 Pfam PF13411 MerR HTH family regulatory protein 7 74 7.7E-14 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_03345 1631147c471280b3f2f371aca9149828 303 SUPERFAMILY SSF46955 7 75 2.2E-15 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_03345 1631147c471280b3f2f371aca9149828 303 Pfam PF02607 B12 binding domain 96 166 1.1E-8 T 15-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_03345 1631147c471280b3f2f371aca9149828 303 SUPERFAMILY SSF52242 178 269 1.29E-12 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_03345 1631147c471280b3f2f371aca9149828 303 Gene3D G3DSA:1.10.1240.10 95 169 1.9E-17 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_03345 1631147c471280b3f2f371aca9149828 303 SMART SM00422 7 76 4.6E-13 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_03345 1631147c471280b3f2f371aca9149828 303 Pfam PF02310 B12 binding domain 179 268 1.3E-12 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 9.9E-53 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 9.9E-53 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 PRINTS PR00069 Aldo-keto reductase signature 95 113 9.9E-53 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 9.9E-53 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 PRINTS PR00069 Aldo-keto reductase signature 39 63 9.9E-53 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 Gene3D G3DSA:3.20.20.100 1 275 8.3E-126 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 PIRSF PIRSF000097 1 272 4.1E-94 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 SUPERFAMILY SSF51430 5 270 6.68E-99 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_12735 27a8e9587cb0ad9c7adc1416d5b9a6d3 275 Pfam PF00248 Aldo/keto reductase family 22 261 1.5E-55 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Gene3D G3DSA:1.10.8.60 481 541 2.1E-15 T 15-10-2018 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Pfam PF02954 Bacterial regulatory protein, Fis family 583 623 5.0E-13 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Pfam PF00158 Sigma-54 interaction domain 312 476 2.9E-69 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Gene3D G3DSA:3.40.50.300 297 480 7.3E-64 T 15-10-2018 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Pfam PF01590 GAF domain 87 202 9.6E-9 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 SUPERFAMILY SSF55781 66 204 1.26E-5 T 15-10-2018 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 SMART SM00382 329 473 3.6E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 SUPERFAMILY SSF46689 577 625 2.37E-9 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 518 527 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 333 346 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Gene3D G3DSA:3.30.450.40 16 203 4.5E-59 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 Gene3D G3DSA:1.10.10.60 563 625 1.2E-11 T 15-10-2018 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 606 625 1.5E-8 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 589 606 1.5E-8 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_17375 72fcdde0133daf4e9be8b98d3d5d6f0f 625 SUPERFAMILY SSF52540 311 534 8.14E-66 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 SUPERFAMILY SSF56112 8 375 3.94E-87 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 Gene3D G3DSA:3.90.1200.10 120 389 1.8E-103 T 15-10-2018 C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 380 2.7E-144 T 15-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 390 181.448 T 15-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 PIRSF PIRSF031134 4 388 1.5E-152 T 15-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 Gene3D G3DSA:3.30.200.20 1 119 9.2E-46 T 15-10-2018 C2I28_14285 46f716c710a0de7b598b4e5b5f4a8ced 390 Pfam PF01636 Phosphotransferase enzyme family 35 269 2.0E-13 T 15-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 Gene3D G3DSA:3.30.450.20 9 140 8.6E-32 T 15-10-2018 C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 Pfam PF00563 EAL domain 328 560 9.1E-71 T 15-10-2018 IPR001633 EAL domain C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 SUPERFAMILY SSF141868 327 570 3.27E-84 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 SUPERFAMILY SSF55785 27 128 5.41E-28 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 SMART SM00052 322 565 1.2E-106 T 15-10-2018 IPR001633 EAL domain C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 Gene3D G3DSA:3.30.70.270 141 325 5.0E-55 T 15-10-2018 C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 Pfam PF08447 PAS fold 41 124 1.7E-14 T 15-10-2018 IPR013655 PAS fold-3 GO:0005515 C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 SUPERFAMILY SSF55073 147 312 7.85E-41 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 26 137 2.3E-16 T 15-10-2018 IPR000014 PAS domain C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 SMART SM00267 131 312 2.0E-54 T 15-10-2018 IPR000160 GGDEF domain C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 Gene3D G3DSA:3.20.20.450 326 571 2.0E-94 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 SMART SM00086 89 131 9.1E-10 T 15-10-2018 IPR001610 PAC motif C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 139 312 1.4E-35 T 15-10-2018 IPR000160 GGDEF domain C2I28_00760 115b9c48fd27b413c032c6cf4311ee9b 571 Pfam PF00990 Diguanylate cyclase, GGDEF domain 142 308 1.3E-43 T 15-10-2018 IPR000160 GGDEF domain C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 SMART SM01240 9 474 0.0 T 15-10-2018 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 4.3E-170 T 15-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 Pfam PF00571 CBS domain 97 144 3.5E-6 T 15-10-2018 IPR000644 CBS domain C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 Pfam PF00571 CBS domain 154 204 1.3E-8 T 15-10-2018 IPR000644 CBS domain C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 SUPERFAMILY SSF51412 5 159 7.32E-31 T 15-10-2018 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 8.8E-206 T 15-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 PIRSF PIRSF000130 1 488 5.8E-213 T 15-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 SUPERFAMILY SSF51412 144 485 2.88E-126 T 15-10-2018 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 Gene3D G3DSA:3.20.20.70 1 487 3.2E-227 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 SMART SM00116 161 209 8.4E-10 T 15-10-2018 IPR000644 CBS domain C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 SMART SM00116 98 148 3.1E-5 T 15-10-2018 IPR000644 CBS domain C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 15-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 C2I28_08075 af016bbd93b0d3873320fb9008c1a748 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 86.882 T 15-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 PIRSF PIRSF000460 3 802 1.0E-240 T 15-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 794 0.0 T 15-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 638 650 - T 15-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 Gene3D G3DSA:3.40.50.2000 14 794 0.0 T 15-10-2018 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 Pfam PF00343 Carbohydrate phosphorylase 93 794 0.0 T 15-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 SUPERFAMILY SSF53756 4 796 0.0 T 15-10-2018 C2I28_06025 865601f74612bc160cb762a8c18877a4 803 Gene3D G3DSA:3.40.50.2000 460 787 0.0 T 15-10-2018 C2I28_01100 f767c3abb6bce48ecfb02fe070086268 439 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 28 410 8.2E-116 T 15-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 C2I28_01100 f767c3abb6bce48ecfb02fe070086268 439 Pfam PF02386 Cation transport protein 36 421 4.7E-65 T 15-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 Gene3D G3DSA:3.40.50.10800 27 346 4.0E-82 T 15-10-2018 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 20 364 2.6E-115 T 15-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 Gene3D G3DSA:3.40.50.10800 228 313 4.0E-82 T 15-10-2018 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 Gene3D G3DSA:3.40.50.10800 110 364 4.0E-82 T 15-10-2018 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 Pfam PF02445 Quinolinate synthetase A protein 27 364 4.0E-107 T 15-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 SUPERFAMILY SSF142754 32 364 8.89E-97 T 15-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I28_04800 ef5ac1891b7f2f6e6f972570efa4a09e 366 Hamap MF_00569 Quinolinate synthase A [nadA]. 20 365 55.685 T 15-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I28_09155 1d16a8fa54b28ab770adfc3598554b1d 278 SUPERFAMILY SSF52091 152 246 7.85E-16 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09155 1d16a8fa54b28ab770adfc3598554b1d 278 Pfam PF08678 Rsbr N terminal 9 138 7.6E-35 T 15-10-2018 IPR014792 RsbS co-antagonist protein RsbRA N-terminal domain C2I28_09155 1d16a8fa54b28ab770adfc3598554b1d 278 Gene3D G3DSA:1.10.490.10 1 138 2.4E-26 T 15-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I28_09155 1d16a8fa54b28ab770adfc3598554b1d 278 Gene3D G3DSA:3.30.750.24 150 270 2.1E-38 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09155 1d16a8fa54b28ab770adfc3598554b1d 278 Pfam PF01740 STAS domain 158 249 2.4E-13 T 15-10-2018 IPR002645 STAS domain C2I28_09155 1d16a8fa54b28ab770adfc3598554b1d 278 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 4 137 4.0E-18 T 15-10-2018 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 Gene3D G3DSA:3.30.300.30 133 220 2.3E-8 T 15-10-2018 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 PRINTS PR01009 Flagellar M-ring protein signature 122 140 1.3E-23 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 PRINTS PR01009 Flagellar M-ring protein signature 154 168 1.3E-23 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 PRINTS PR01009 Flagellar M-ring protein signature 348 372 1.3E-23 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 PRINTS PR01009 Flagellar M-ring protein signature 198 216 1.3E-23 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 PRINTS PR01009 Flagellar M-ring protein signature 270 288 1.3E-23 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 Pfam PF08345 Flagellar M-ring protein C-terminal 257 430 5.0E-24 T 15-10-2018 IPR013556 Flagellar M-ring C-terminal C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 PIRSF PIRSF004862 1 530 4.1E-112 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 Pfam PF01514 Secretory protein of YscJ/FliF family 32 220 3.4E-56 T 15-10-2018 IPR006182 Secretory protein YscJ/FliF C2I28_02530 d7dfc561839d4ca25fd957d11f3d8848 530 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 530 4.3E-128 T 15-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 SUPERFAMILY SSF50331 241 346 2.68E-12 T 15-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 SMART SM00382 33 216 2.8E-20 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 Pfam PF08402 TOBE domain 278 346 1.0E-6 T 15-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 Gene3D G3DSA:2.40.50.940 227 345 6.5E-12 T 15-10-2018 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 Gene3D G3DSA:2.40.50.140 284 338 6.5E-12 T 15-10-2018 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 Gene3D G3DSA:3.40.50.300 7 226 3.8E-69 T 15-10-2018 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 Pfam PF00005 ABC transporter 24 166 4.5E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09055 1a60bdd7d7fce081fcbb28aa0de1ab7c 369 SUPERFAMILY SSF52540 7 248 3.82E-85 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 8.9E-73 T 15-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 4.8E-33 T 15-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.108 T 15-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 Gene3D G3DSA:3.30.230.10 74 166 4.7E-36 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.8E-29 T 15-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 SUPERFAMILY SSF54768 8 76 1.46E-25 T 15-10-2018 C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 SUPERFAMILY SSF54211 80 159 1.29E-25 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 15-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site C2I28_08770 dd18084d9792112a166b82e7d56b0e77 166 Gene3D G3DSA:3.30.160.20 1 73 7.0E-36 T 15-10-2018 C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 SUPERFAMILY SSF88946 3 94 5.76E-25 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 173 5.8E-24 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 SUPERFAMILY SSF88659 119 175 1.29E-11 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 Pfam PF08281 Sigma-70, region 4 125 166 1.2E-8 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 Gene3D G3DSA:1.10.1740.10 2 113 4.4E-25 T 15-10-2018 C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 Gene3D G3DSA:1.10.10.10 123 176 6.0E-13 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22540 92989c643d10118f91b15a65b6ff2b25 176 Pfam PF04542 Sigma-70 region 2 23 90 4.4E-12 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 Gene3D G3DSA:1.10.40.30 349 430 1.3E-33 T 15-10-2018 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 2.9E-24 T 15-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 Pfam PF00206 Lyase 6 286 1.0E-74 T 15-10-2018 IPR022761 Fumarate lyase, N-terminal C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 3.8E-182 T 15-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 15-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.0E-26 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 2.0E-26 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 2.0E-26 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 2.0E-26 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 3.3E-10 T 15-10-2018 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 3.3E-10 T 15-10-2018 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 3.3E-10 T 15-10-2018 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 3.3E-10 T 15-10-2018 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 SUPERFAMILY SSF48557 3 427 8.8E-140 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 Gene3D G3DSA:1.10.275.10 1 92 1.8E-39 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 SMART SM00998 349 429 2.5E-38 T 15-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09435 a2abbe4b20bd493f9f00ece4284e4079 430 Gene3D G3DSA:1.20.200.10 93 348 1.4E-102 T 15-10-2018 C2I28_15280 574f347250063902822dab97b6a89456 286 Gene3D G3DSA:3.40.190.10 91 269 7.1E-30 T 15-10-2018 C2I28_15280 574f347250063902822dab97b6a89456 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-20 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_15280 574f347250063902822dab97b6a89456 286 Gene3D G3DSA:3.40.190.10 161 263 7.1E-30 T 15-10-2018 C2I28_15280 574f347250063902822dab97b6a89456 286 Gene3D G3DSA:1.10.10.10 1 83 4.3E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_15280 574f347250063902822dab97b6a89456 286 SUPERFAMILY SSF46785 1 83 1.02E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15280 574f347250063902822dab97b6a89456 286 Pfam PF03466 LysR substrate binding domain 90 268 3.1E-29 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_15280 574f347250063902822dab97b6a89456 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_15280 574f347250063902822dab97b6a89456 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_15280 574f347250063902822dab97b6a89456 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_15280 574f347250063902822dab97b6a89456 286 SUPERFAMILY SSF53850 91 269 8.69E-27 T 15-10-2018 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 Pfam PF05683 Fumarase C-terminus 290 495 9.1E-63 T 15-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 Gene3D G3DSA:3.20.130.10 309 494 7.4E-66 T 15-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 SUPERFAMILY SSF117457 322 493 9.68E-52 T 15-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 Pfam PF05681 Fumarate hydratase (Fumerase) 7 283 3.2E-73 T 15-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 PIRSF PIRSF001394 1 512 8.6E-197 T 15-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 7 281 3.1E-62 T 15-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 C2I28_10010 a1c22e359a86b46dde8059409373f44b 513 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 332 493 6.1E-52 T 15-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 PIRSF PIRSF016578 5 115 0.003 T 15-10-2018 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 PIRSF PIRSF016578 124 363 1.6E-16 T 15-10-2018 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 Gene3D G3DSA:1.20.140.10 233 375 2.6E-56 T 15-10-2018 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 Gene3D G3DSA:1.10.540.10 2 118 4.1E-38 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 374 5.6E-51 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 5.4E-28 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 SUPERFAMILY SSF56645 3 239 1.7E-82 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 116 4.3E-34 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 SUPERFAMILY SSF47203 225 375 4.19E-59 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_07490 6f7de5cec0e17d837bc9e9e8f0e8b192 375 Gene3D G3DSA:2.40.110.10 119 232 6.8E-48 T 15-10-2018 C2I28_01105 8ef97044406f84f72d25a380b34c28cc 219 Pfam PF02080 TrkA-C domain 149 216 8.9E-15 T 15-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I28_01105 8ef97044406f84f72d25a380b34c28cc 219 Gene3D G3DSA:3.40.50.720 1 137 1.5E-34 T 15-10-2018 C2I28_01105 8ef97044406f84f72d25a380b34c28cc 219 SUPERFAMILY SSF116726 131 216 1.7E-20 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_01105 8ef97044406f84f72d25a380b34c28cc 219 Pfam PF02254 TrkA-N domain 5 120 2.1E-24 T 15-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I28_01105 8ef97044406f84f72d25a380b34c28cc 219 SUPERFAMILY SSF51735 3 134 2.57E-33 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_01105 8ef97044406f84f72d25a380b34c28cc 219 Gene3D G3DSA:3.30.70.1450 138 219 6.0E-27 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 SUPERFAMILY SSF53244 340 493 1.28E-23 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 Pfam PF01225 Mur ligase family, catalytic domain 23 72 4.9E-8 T 15-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 Gene3D G3DSA:3.40.1190.10 107 341 2.7E-69 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 419 1.6E-9 T 15-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 SUPERFAMILY SSF53623 108 335 1.83E-61 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 113 136 - T 15-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 Gene3D G3DSA:3.40.1390.10 3 105 4.0E-19 T 15-10-2018 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 Gene3D G3DSA:3.90.190.20 342 497 7.9E-29 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 Pfam PF08245 Mur ligase middle domain 115 317 2.8E-47 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_18595 7ee960233ad4ae3c323507500003d775 499 SUPERFAMILY SSF63418 16 104 2.22E-16 T 15-10-2018 IPR035911 MurE/MurF, N-terminal C2I28_18595 7ee960233ad4ae3c323507500003d775 499 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 492 4.4E-113 T 15-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I28_17335 9b41f1babb35192c9c5ce11215baec79 478 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 39 259 1.6E-13 T 15-10-2018 C2I28_17335 9b41f1babb35192c9c5ce11215baec79 478 Gene3D G3DSA:3.50.50.60 29 305 9.4E-30 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17335 9b41f1babb35192c9c5ce11215baec79 478 SUPERFAMILY SSF51905 36 381 8.2E-26 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 9.2E-38 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 Pfam PF01084 Ribosomal protein S18 23 73 1.7E-28 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 15-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 78 22.634 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 Gene3D G3DSA:4.10.640.10 3 78 8.7E-32 T 15-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 1.9E-21 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 1.9E-21 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 1.9E-21 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 1.9E-21 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 77 3.0E-23 T 15-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07925 8c7464ed27d6c2b2a21001ca375ccd44 79 SUPERFAMILY SSF46911 6 77 2.09E-31 T 15-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_16790 679eb0d1e276e760c1ca00475d536806 146 Pfam PF10027 Predicted integral membrane protein (DUF2269) 7 143 5.6E-7 T 15-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane C2I28_02210 9c1e19ef9c54638003ab37dc5d7faca5 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 334 4.2E-42 T 15-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1386 1473 3.57E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1838 1928 9.57E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 2665 2752 3.85E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 3494 3573 1.33E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 3854 3935 3.0E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 834 922 7.3E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 2019 2107 2.8E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1380 1468 1.0E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1288 1377 4.5E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 3299 3388 1.3E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 652 740 8.9E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 924 1013 3.7E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 2662 2747 1.9E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1470 1559 4.5E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 3028 3113 2.3E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1198 1286 3.8E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1562 1650 5.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1106 1195 4.5E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 3846 3935 6.7E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 2843 2930 2.4E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 2113 2198 1.6E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1835 1924 2.3E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1744 1832 2.3E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 2294 2381 2.3E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 3211 3296 4.6E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1016 1104 5.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 2479 2564 1.9E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 742 831 3.7E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 Gene3D G3DSA:2.60.40.10 1653 1741 1.4E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 855 926 2.43E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 670 744 2.86E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1750 1837 1.14E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 3214 3301 2.43E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1022 1109 1.57E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1113 1201 3.85E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 931 1019 5.42E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1204 1291 5.0E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 749 837 6.85E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 2031 2111 6.28E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 568 654 4.14E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1477 1564 4.14E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1584 1657 0.47 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1038 1111 0.53 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1766 1839 0.36 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 765 838 0.18 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 2773 2846 1.7 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 2315 2388 0.92 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 3504 3577 2.2 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1129 1202 0.14 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 3047 3120 0.92 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1311 1384 0.14 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1493 1566 0.14 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 583 656 0.044 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 3230 3303 0.37 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 674 747 0.53 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1675 1748 0.11 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 856 929 0.53 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 2498 2571 0.73 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1402 1475 0.6 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 947 1020 0.18 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 2864 2937 0.8 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 492 565 1.8 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 2681 2754 0.73 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1220 1293 0.59 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 1857 1931 1.4 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SMART SM00112 2132 2205 0.55 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1659 1747 1.71E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 2482 2569 1.96E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 2848 2935 2.0E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 2299 2386 3.85E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1568 1655 1.57E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 1295 1383 3.85E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 4406 4480 6.71E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27315 84411f9c8b64de0acad94066acd55113 4603 SUPERFAMILY SSF49313 3031 3118 4.85E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_19370 4fe104fab655eb3f5491ef5e49c3bdc7 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_19370 4fe104fab655eb3f5491ef5e49c3bdc7 482 Gene3D G3DSA:3.40.309.10 249 439 1.3E-177 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_19370 4fe104fab655eb3f5491ef5e49c3bdc7 482 Pfam PF00171 Aldehyde dehydrogenase family 19 469 3.2E-171 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_19370 4fe104fab655eb3f5491ef5e49c3bdc7 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_19370 4fe104fab655eb3f5491ef5e49c3bdc7 482 SUPERFAMILY SSF53720 18 472 1.03E-159 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_19370 4fe104fab655eb3f5491ef5e49c3bdc7 482 Gene3D G3DSA:3.40.605.10 18 464 1.3E-177 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_00855 50eca09ea9a4f3cb6711be269660bbf4 226 Pfam PF02517 CAAX protease self-immunity 129 217 2.1E-20 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_20105 7bcfde9eb9251f57b79e18901d8143b3 120 Gene3D G3DSA:1.10.490.10 1 120 2.6E-40 T 15-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I28_20105 7bcfde9eb9251f57b79e18901d8143b3 120 PIRSF PIRSF002030 1 120 3.1E-43 T 15-10-2018 IPR016339 Truncated hemoglobin, group 1 C2I28_20105 7bcfde9eb9251f57b79e18901d8143b3 120 SUPERFAMILY SSF46458 3 117 5.32E-34 T 15-10-2018 IPR009050 Globin-like superfamily C2I28_20105 7bcfde9eb9251f57b79e18901d8143b3 120 Pfam PF01152 Bacterial-like globin 4 118 4.7E-27 T 15-10-2018 IPR001486 Truncated hemoglobin GO:0019825 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 Gene3D G3DSA:1.10.540.10 1 120 2.6E-33 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 SUPERFAMILY SSF47203 228 380 7.09E-55 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.6E-27 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.6E-49 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 Gene3D G3DSA:1.20.140.10 236 380 1.7E-56 T 15-10-2018 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 Gene3D G3DSA:2.40.110.10 121 235 6.2E-43 T 15-10-2018 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 SUPERFAMILY SSF56645 1 242 1.09E-79 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 2.5E-27 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 PIRSF PIRSF016578 126 377 1.2E-12 T 15-10-2018 C2I28_17240 60a6227b39f09867c435e27e01ca6d1a 382 PIRSF PIRSF016578 8 81 0.41 T 15-10-2018 C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 Gene3D G3DSA:3.40.47.10 266 420 3.8E-40 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 Gene3D G3DSA:3.40.47.10 1 262 4.2E-62 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 161 177 - T 15-10-2018 IPR018201 Beta-ketoacyl synthase, active site C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 375 4.0E-29 T 15-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 SUPERFAMILY SSF53901 221 418 4.12E-57 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 SMART SM00825 Beta-ketoacyl synthase 4 414 3.5E-9 T 15-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 253 2.9E-34 T 15-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal C2I28_26480 915cb7a9c6cbf752407c8b8c6e2f21a7 423 SUPERFAMILY SSF53901 3 260 5.76E-49 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_24750 adda22983f8768c81df68c69124810ac 290 Gene3D G3DSA:1.10.10.10 1 81 2.6E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24750 adda22983f8768c81df68c69124810ac 290 Gene3D G3DSA:3.40.190.290 82 287 3.5E-30 T 15-10-2018 C2I28_24750 adda22983f8768c81df68c69124810ac 290 Pfam PF03466 LysR substrate binding domain 86 289 4.6E-31 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_24750 adda22983f8768c81df68c69124810ac 290 SUPERFAMILY SSF46785 1 109 9.86E-17 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24750 adda22983f8768c81df68c69124810ac 290 SUPERFAMILY SSF53850 85 289 7.53E-32 T 15-10-2018 C2I28_24750 adda22983f8768c81df68c69124810ac 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.6E-14 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_11740 c2b15345666d06a9aa98baa4564f13e7 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 7.2E-38 T 15-10-2018 IPR006504 Transcriptional regulator Spx/MgsR C2I28_11740 c2b15345666d06a9aa98baa4564f13e7 132 SUPERFAMILY SSF52833 1 129 4.16E-40 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_11740 c2b15345666d06a9aa98baa4564f13e7 132 Pfam PF03960 ArsC family 5 113 2.9E-24 T 15-10-2018 IPR006660 Arsenate reductase-like C2I28_11740 c2b15345666d06a9aa98baa4564f13e7 132 Gene3D G3DSA:3.40.30.10 1 131 2.8E-48 T 15-10-2018 C2I28_11740 c2b15345666d06a9aa98baa4564f13e7 132 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.766 T 15-10-2018 IPR023731 Regulatory protein Spx GO:0045892 C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 Pfam PF01047 MarR family 34 91 9.3E-14 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 Gene3D G3DSA:1.10.10.10 1 139 5.0E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 4.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 4.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 SUPERFAMILY SSF46785 7 137 1.99E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_14145 fc4c891bb3934421d0df6abbff94d6a1 142 SMART SM00347 27 127 1.9E-24 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21820 01f2155b0591bd777e2f6154ecb20df8 142 Pfam PF14568 SMI1-KNR4 cell-wall 13 136 5.9E-22 T 15-10-2018 C2I28_21820 01f2155b0591bd777e2f6154ecb20df8 142 SMART SM00860 9 138 1.1E-7 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_21820 01f2155b0591bd777e2f6154ecb20df8 142 Gene3D G3DSA:3.40.1580.10 4 142 1.2E-23 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_21820 01f2155b0591bd777e2f6154ecb20df8 142 SUPERFAMILY SSF160631 8 141 1.12E-20 T 15-10-2018 C2I28_25465 2f4c9b62cd201930d2365ef01bd314d9 229 Pfam PF06912 Protein of unknown function (DUF1275) 11 216 1.6E-36 T 15-10-2018 IPR010699 Protein of unknown function DUF1275 C2I28_25380 434d92cd9f41957b790840c38f9fa24d 285 SUPERFAMILY SSF52091 165 273 1.04E-17 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_25380 434d92cd9f41957b790840c38f9fa24d 285 Gene3D G3DSA:3.30.750.24 162 278 2.4E-34 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_25380 434d92cd9f41957b790840c38f9fa24d 285 Pfam PF01740 STAS domain 168 270 2.4E-15 T 15-10-2018 IPR002645 STAS domain C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 Pfam PF13353 4Fe-4S single cluster domain 22 128 1.3E-8 T 15-10-2018 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 338 1.4E-119 T 15-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 Gene3D G3DSA:3.20.20.70 2 338 3.1E-105 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 Pfam PF04055 Radical SAM superfamily 19 182 2.7E-30 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 SUPERFAMILY SSF102114 6 282 4.58E-78 T 15-10-2018 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 Pfam PF06463 Molybdenum Cofactor Synthesis C 190 316 1.1E-36 T 15-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 15-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 338 40.662 T 15-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06750 0f865c0ffd5afb180e7d1cb4c052f09e 338 SMART SM00729 14 222 5.8E-14 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.8E-102 T 15-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 15-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 PIRSF PIRSF005902 1 256 3.0E-95 T 15-10-2018 IPR001130 TatD family GO:0016788 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 15-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 SUPERFAMILY SSF51556 2 255 4.17E-100 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 Gene3D G3DSA:3.20.20.140 1 256 6.7E-115 T 15-10-2018 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 15-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 C2I28_08305 1de74c0fbd5e24c8d94b9972e6ae25e5 256 Pfam PF01026 TatD related DNase 3 252 1.2E-92 T 15-10-2018 IPR001130 TatD family GO:0016788 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 Gene3D G3DSA:2.60.40.1180 481 561 2.5E-25 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 Pfam PF00128 Alpha amylase, catalytic domain 28 377 1.6E-129 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 558 7.1E-272 T 15-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 SMART SM00642 13 419 1.2E-158 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 SUPERFAMILY SSF51011 480 559 1.2E-18 T 15-10-2018 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 Gene3D G3DSA:3.20.20.80 5 472 2.2E-201 T 15-10-2018 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 Gene3D G3DSA:3.90.400.10 105 175 2.2E-201 T 15-10-2018 C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 SUPERFAMILY SSF51445 4 477 1.69E-158 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_12950 bb984a0ad91e0626bb260bc2016dd924 561 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 553 7.1E-7 T 15-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I28_21395 37edf2d4b9ff7acb36b2288b5d97263b 312 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_21395 37edf2d4b9ff7acb36b2288b5d97263b 312 Gene3D G3DSA:3.40.50.300 1 238 4.3E-66 T 15-10-2018 C2I28_21395 37edf2d4b9ff7acb36b2288b5d97263b 312 SUPERFAMILY SSF52540 3 222 4.86E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21395 37edf2d4b9ff7acb36b2288b5d97263b 312 SMART SM00382 28 219 2.2E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_21395 37edf2d4b9ff7acb36b2288b5d97263b 312 Pfam PF00005 ABC transporter 19 162 3.0E-30 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_17355 3654c1546a165bdd856aa912ae65fbcf 331 Pfam PF00676 Dehydrogenase E1 component 23 319 9.3E-97 T 15-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I28_17355 3654c1546a165bdd856aa912ae65fbcf 331 SUPERFAMILY SSF52518 10 330 3.5E-102 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_17355 3654c1546a165bdd856aa912ae65fbcf 331 Gene3D G3DSA:3.40.50.970 2 331 2.2E-125 T 15-10-2018 C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 Pfam PF13361 UvrD-like helicase C-terminal domain 418 750 5.3E-43 T 15-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 Pfam PF00580 UvrD/REP helicase N-terminal domain 151 412 8.8E-64 T 15-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 Gene3D G3DSA:1.10.486.10 524 673 5.4E-75 T 15-10-2018 C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 Gene3D G3DSA:3.40.50.300 150 414 3.4E-84 T 15-10-2018 C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 Gene3D G3DSA:3.40.50.300 422 766 5.4E-75 T 15-10-2018 C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 Gene3D G3DSA:1.10.10.160 256 331 3.4E-84 T 15-10-2018 IPR013986 DExx box DNA helicase domain superfamily C2I28_11890 ad506d9f2b223f26b0bcdf86c3530449 772 SUPERFAMILY SSF52540 145 769 1.01E-130 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 Gene3D G3DSA:1.10.10.10 160 259 4.8E-47 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 Gene3D G3DSA:3.30.450.40 1 159 6.2E-71 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 SUPERFAMILY SSF46785 167 256 2.77E-42 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 Pfam PF06018 CodY GAF-like domain 3 178 2.0E-81 T 15-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 PIRSF PIRSF011572 1 257 5.3E-123 T 15-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 1.4E-125 T 15-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 Pfam PF08222 CodY helix-turn-helix domain 198 257 2.0E-37 T 15-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal C2I28_02550 5ae5b4e2020806d34ebd62289cddf573 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 150.036 T 15-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 SUPERFAMILY SSF56784 1 267 5.9E-75 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 Gene3D G3DSA:3.40.50.1000 4 263 2.2E-84 T 15-10-2018 IPR023214 HAD superfamily C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 15-10-2018 C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 261 7.4E-65 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 3.4E-28 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 Gene3D G3DSA:3.30.1240.10 87 191 2.2E-84 T 15-10-2018 C2I28_18110 c09df0b0eb13e86033e24140d1f976a1 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 1.4E-66 T 15-10-2018 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Gene3D G3DSA:3.40.50.620 124 431 1.9E-180 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Pfam PF05746 DALR anticodon binding domain 438 556 2.0E-39 T 15-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 SUPERFAMILY SSF47323 431 556 6.54E-37 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 SMART SM01016 5 95 1.8E-36 T 15-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 SUPERFAMILY SSF52374 118 448 6.19E-99 T 15-10-2018 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Gene3D G3DSA:1.10.730.10 432 556 1.9E-180 T 15-10-2018 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 94 4.2E-26 T 15-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Gene3D G3DSA:3.30.1360.70 2 113 2.7E-29 T 15-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 556 28.985 T 15-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 556 1.1E-177 T 15-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 Pfam PF00750 tRNA synthetases class I (R) 106 400 6.4E-31 T 15-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 SUPERFAMILY SSF55190 2 115 3.79E-28 T 15-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 6.3E-25 T 15-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 6.3E-25 T 15-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 6.3E-25 T 15-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 6.3E-25 T 15-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 C2I28_07520 c07956776cf4ca82d70e0c428849249b 556 SMART SM00836 437 556 3.6E-54 T 15-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 C2I28_04815 71303c391245b03192a90c465db5839f 378 Pfam PF00266 Aminotransferase class-V 2 364 6.3E-78 T 15-10-2018 IPR000192 Aminotransferase class V domain C2I28_04815 71303c391245b03192a90c465db5839f 378 Gene3D G3DSA:1.10.260.50 13 277 9.7E-123 T 15-10-2018 C2I28_04815 71303c391245b03192a90c465db5839f 378 PIRSF PIRSF005572 1 376 9.0E-121 T 15-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I28_04815 71303c391245b03192a90c465db5839f 378 Gene3D G3DSA:3.90.1150.10 2 367 9.7E-123 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_04815 71303c391245b03192a90c465db5839f 378 Gene3D G3DSA:3.40.640.10 59 233 9.7E-123 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_04815 71303c391245b03192a90c465db5839f 378 SUPERFAMILY SSF53383 1 368 3.29E-94 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SMART SM00483 1 314 1.2E-68 T 15-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Gene3D G3DSA:3.30.460.10 152 258 1.9E-24 T 15-10-2018 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SUPERFAMILY SSF89550 335 568 1.7E-54 T 15-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Gene3D G3DSA:3.20.20.140 324 570 3.5E-75 T 15-10-2018 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Pfam PF14716 Helix-hairpin-helix domain 4 69 7.4E-20 T 15-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Pfam PF02811 PHP domain 337 464 1.9E-8 T 15-10-2018 IPR004013 PHP domain GO:0003824 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Gene3D G3DSA:1.10.150.20 83 147 1.2E-19 T 15-10-2018 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SMART SM00278 88 107 19.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SMART SM00278 48 67 5.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SMART SM00278 123 142 13.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Pfam PF14791 DNA polymerase beta thumb 253 314 6.0E-19 T 15-10-2018 IPR029398 DNA polymerase beta, thumb domain C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SUPERFAMILY SSF47802 2 81 2.09E-20 T 15-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Gene3D G3DSA:3.30.210.10 259 323 8.3E-18 T 15-10-2018 IPR037160 DNA polymerase, thumb domain superfamily C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 PIRSF PIRSF005047 1 570 1.7E-241 T 15-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SMART SM00481 336 415 2.8E-22 T 15-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Pfam PF14520 Helix-hairpin-helix domain 90 144 3.4E-6 T 15-10-2018 C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 Gene3D G3DSA:1.10.150.110 1 82 4.1E-20 T 15-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily C2I28_05245 0a3a9c536b2d51472517c3b0c93774bf 570 SUPERFAMILY SSF81301 152 314 4.51E-45 T 15-10-2018 C2I28_13315 519893c4f20a78fa985b2a7e3dd9ac7f 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 322 9.4E-136 T 15-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 C2I28_13315 519893c4f20a78fa985b2a7e3dd9ac7f 326 Gene3D G3DSA:3.40.50.720 2 263 5.2E-126 T 15-10-2018 C2I28_13315 519893c4f20a78fa985b2a7e3dd9ac7f 326 SUPERFAMILY SSF51735 2 320 1.64E-97 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_13315 519893c4f20a78fa985b2a7e3dd9ac7f 326 Gene3D G3DSA:3.90.25.10 183 318 5.2E-126 T 15-10-2018 C2I28_13315 519893c4f20a78fa985b2a7e3dd9ac7f 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 251 3.2E-59 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 Gene3D G3DSA:1.20.120.1810 1 102 7.2E-17 T 15-10-2018 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 PRINTS PR00046 Major sigma-70 factor signature 238 249 5.2E-10 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 PRINTS PR00046 Major sigma-70 factor signature 206 218 5.2E-10 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 PRINTS PR00046 Major sigma-70 factor signature 223 238 5.2E-10 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 PRINTS PR00046 Major sigma-70 factor signature 58 71 5.2E-10 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 SUPERFAMILY SSF88659 107 181 1.44E-14 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 252 3.2E-34 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 58 71 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 Gene3D G3DSA:1.10.10.10 104 157 1.6E-16 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 Pfam PF04539 Sigma-70 region 3 113 186 8.1E-16 T 15-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 253 2.3E-90 T 15-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 Gene3D G3DSA:1.10.10.10 198 256 3.3E-12 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 Pfam PF04545 Sigma-70, region 4 203 250 6.1E-17 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 SUPERFAMILY SSF88659 180 255 3.74E-16 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 SUPERFAMILY SSF88946 11 103 1.57E-26 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 1 254 7.6E-133 T 15-10-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 C2I28_09185 918f93f7423670737d83b3baf0aa6a60 264 Pfam PF04542 Sigma-70 region 2 34 103 1.1E-16 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 SMART SM00418 19 97 1.2E-25 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 SUPERFAMILY SSF46785 9 100 8.49E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 Pfam PF01022 Bacterial regulatory protein, arsR family 26 72 4.8E-14 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 1.5E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.5E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 1.5E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_09955 ff910c422fa660922a5e5304cbfaef82 105 Gene3D G3DSA:1.10.10.10 1 105 4.7E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19045 486cfca73e9c80e3baa3908e29d302be 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 19 267 49.848 T 15-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 C2I28_19045 486cfca73e9c80e3baa3908e29d302be 273 Gene3D G3DSA:3.40.50.620 2 273 1.6E-86 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_19045 486cfca73e9c80e3baa3908e29d302be 273 Pfam PF02540 NAD synthase 24 264 3.4E-75 T 15-10-2018 IPR022310 NAD/GMP synthase C2I28_19045 486cfca73e9c80e3baa3908e29d302be 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 20 273 7.8E-80 T 15-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 C2I28_19045 486cfca73e9c80e3baa3908e29d302be 273 SUPERFAMILY SSF52402 4 272 3.93E-82 T 15-10-2018 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 SUPERFAMILY SSF48452 399 504 5.31E-18 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 Pfam PF01694 Rhomboid family 220 355 4.7E-36 T 15-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 Gene3D G3DSA:1.25.40.10 394 506 1.1E-16 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 SMART SM00028 427 460 17.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 SMART SM00028 461 494 0.057 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 SMART SM00028 393 426 390.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 Gene3D G3DSA:1.20.1540.10 175 366 1.9E-49 T 15-10-2018 IPR035952 Rhomboid-like superfamily C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 Pfam PF13181 Tetratricopeptide repeat 428 458 0.061 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04075 f08ad2ef98a0e000651660890c5797f9 506 SUPERFAMILY SSF144091 176 360 1.05E-43 T 15-10-2018 C2I28_10695 8afefa8ca61f4454de5e238d02636d37 513 PIRSF PIRSF002741 1 512 1.4E-89 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_10695 8afefa8ca61f4454de5e238d02636d37 513 SUPERFAMILY SSF53850 38 506 2.26E-109 T 15-10-2018 C2I28_10695 8afefa8ca61f4454de5e238d02636d37 513 Gene3D G3DSA:3.10.105.10 262 469 4.2E-133 T 15-10-2018 C2I28_10695 8afefa8ca61f4454de5e238d02636d37 513 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 429 3.1E-79 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_10695 8afefa8ca61f4454de5e238d02636d37 513 Gene3D G3DSA:3.40.190.10 54 261 4.2E-133 T 15-10-2018 C2I28_00740 18cd162e7f93243ff1526012588ccd47 267 Gene3D G3DSA:2.30.320.10 5 267 2.2E-86 T 15-10-2018 IPR035948 YwqG-like superfamily C2I28_00740 18cd162e7f93243ff1526012588ccd47 267 Pfam PF09234 Domain of unknown function (DUF1963) 42 266 6.3E-61 T 15-10-2018 IPR015315 Protein of unknown function DUF1963 C2I28_00740 18cd162e7f93243ff1526012588ccd47 267 SUPERFAMILY SSF103032 7 267 4.71E-70 T 15-10-2018 IPR035948 YwqG-like superfamily C2I28_25610 10870700388927100c89a10bbf745f8b 467 Pfam PF07670 Nucleoside recognition 140 228 3.0E-9 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_25610 10870700388927100c89a10bbf745f8b 467 Pfam PF07670 Nucleoside recognition 310 434 9.6E-19 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_25610 10870700388927100c89a10bbf745f8b 467 Pfam PF07664 Ferrous iron transport protein B C terminus 253 300 1.2E-12 T 15-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 C2I28_20265 4738e0da3380decb26d3e34c626d2a48 214 Pfam PF13460 NAD(P)H-binding 7 190 9.1E-50 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_20265 4738e0da3380decb26d3e34c626d2a48 214 Gene3D G3DSA:3.40.50.720 2 214 1.9E-55 T 15-10-2018 C2I28_20265 4738e0da3380decb26d3e34c626d2a48 214 SUPERFAMILY SSF51735 1 205 4.38E-44 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 SUPERFAMILY SSF51419 30 299 3.93E-80 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 6.2E-160 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 33 388 1.6E-17 T 15-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 63 81 - T 15-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 41.197 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 Gene3D G3DSA:2.40.37.10 17 427 7.2E-160 T 15-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 SUPERFAMILY SSF50621 276 431 2.07E-54 T 15-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 7.7E-32 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 7.7E-32 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 7.7E-32 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 7.7E-32 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 7.5E-19 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 7.5E-19 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 7.5E-19 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 7.5E-19 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 7.5E-19 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 296 2.7E-71 T 15-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 C2I28_03480 8bc04be42ed566f58bab1981555697a1 439 Gene3D G3DSA:3.20.20.10 38 297 7.2E-160 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_09515 df5f055be037172ded60082fbaba8e92 668 PIRSF PIRSF001604 1 668 3.3E-265 T 15-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SMART SM00278 475 494 1.2 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SMART SM00278 539 558 2.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SMART SM00278 441 460 93.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SUPERFAMILY SSF47781 400 580 8.9E-68 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Pfam PF12826 Helix-hairpin-helix motif 505 568 1.9E-25 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Hamap MF_01588 DNA ligase [ligA]. 4 666 54.349 T 15-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SUPERFAMILY SSF50249 313 396 1.58E-28 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:3.40.50.10190 582 667 1.8E-26 T 15-10-2018 IPR036420 BRCT domain superfamily C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 314 4.4E-133 T 15-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Pfam PF14520 Helix-hairpin-helix domain 443 495 2.5E-6 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 318 394 3.6E-34 T 15-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 403 429 3.4E-11 T 15-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 15-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SMART SM00292 592 668 8.6E-12 T 15-10-2018 IPR001357 BRCT domain C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:2.40.50.140 314 386 7.9E-30 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SUPERFAMILY SSF52113 593 664 1.6E-18 T 15-10-2018 IPR036420 BRCT domain superfamily C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:1.10.150.20 427 499 1.2E-32 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:1.10.287.610 1 72 4.3E-28 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SMART SM00532 5 443 8.4E-288 T 15-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 662 1.9E-13 T 15-10-2018 IPR001357 BRCT domain C2I28_09515 df5f055be037172ded60082fbaba8e92 668 SUPERFAMILY SSF56091 2 312 6.84E-123 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:1.10.150.20 500 581 1.1E-28 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 15-10-2018 IPR018239 NAD-dependent DNA ligase, active site C2I28_09515 df5f055be037172ded60082fbaba8e92 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 662 1.4E-279 T 15-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:2.20.70.80 387 424 1.5E-12 T 15-10-2018 C2I28_09515 df5f055be037172ded60082fbaba8e92 668 Gene3D G3DSA:3.30.470.90 73 313 1.1E-101 T 15-10-2018 C2I28_15865 fc0a9df0c2b0eefec5003f4e89e36a23 461 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_15865 fc0a9df0c2b0eefec5003f4e89e36a23 461 PIRSF PIRSF006060 1 459 3.9E-66 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_15865 fc0a9df0c2b0eefec5003f4e89e36a23 461 Pfam PF00324 Amino acid permease 14 424 1.8E-103 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_15865 fc0a9df0c2b0eefec5003f4e89e36a23 461 Gene3D G3DSA:1.20.1740.10 5 457 6.0E-59 T 15-10-2018 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 PRINTS PR01183 Ribonucleotide reductase large chain signature 437 448 4.0E-37 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 PRINTS PR01183 Ribonucleotide reductase large chain signature 554 577 4.0E-37 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 PRINTS PR01183 Ribonucleotide reductase large chain signature 615 642 4.0E-37 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 PRINTS PR01183 Ribonucleotide reductase large chain signature 488 511 4.0E-37 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 PRINTS PR01183 Ribonucleotide reductase large chain signature 526 548 4.0E-37 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 PRINTS PR01183 Ribonucleotide reductase large chain signature 296 315 4.0E-37 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 SUPERFAMILY SSF51998 220 745 1.37E-168 T 15-10-2018 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 141 217 2.8E-19 T 15-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 144 733 6.5E-176 T 15-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 SUPERFAMILY SSF48168 10 219 2.09E-58 T 15-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 Gene3D G3DSA:3.20.70.20 71 740 4.6E-208 T 15-10-2018 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 Pfam PF02867 Ribonucleotide reductase, barrel domain 221 730 3.9E-147 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05980 f8a8cb840755f12851a8bb92adfa1cf9 747 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 604 626 - T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Gene3D G3DSA:3.30.70.3380 377 488 3.5E-44 T 15-10-2018 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.8E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.8E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.8E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.8E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 SUPERFAMILY SSF52540 9 214 1.98E-56 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 4.4E-21 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 15-10-2018 IPR031157 Tr-type G domain, conserved site C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 SUPERFAMILY SSF54980 301 379 8.27E-19 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Gene3D G3DSA:3.30.70.870 295 376 4.2E-36 T 15-10-2018 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 SUPERFAMILY SSF50447 175 297 1.26E-32 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 314.624 T 15-10-2018 IPR006297 Elongation factor 4 GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Gene3D G3DSA:3.30.70.2570 489 563 7.7E-36 T 15-10-2018 IPR038363 LepA, C-terminal domain superfamily C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 2.2E-54 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Pfam PF03144 Elongation factor Tu domain 2 214 284 3.1E-11 T 15-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 15-10-2018 IPR006297 Elongation factor 4 GO:0005525 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Gene3D G3DSA:2.40.30.10 195 294 2.9E-35 T 15-10-2018 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 SMART SM00838 410 495 1.1E-4 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Gene3D G3DSA:3.40.50.300 9 194 2.9E-75 T 15-10-2018 C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 1.0E-52 T 15-10-2018 IPR013842 GTP-binding protein LepA, C-terminal C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 Pfam PF00679 Elongation factor G C-terminus 408 495 2.2E-26 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_04400 f100b87733b2991f9edafca1131aaf09 607 SUPERFAMILY SSF54980 408 503 3.88E-28 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_08105 c4ff6cb7926f733e52ab1f8e529a04d6 226 Pfam PF01712 Deoxynucleoside kinase 16 215 1.1E-64 T 15-10-2018 IPR031314 Deoxynucleoside kinase domain C2I28_08105 c4ff6cb7926f733e52ab1f8e529a04d6 226 PIRSF PIRSF000705 3 222 1.4E-65 T 15-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 C2I28_08105 c4ff6cb7926f733e52ab1f8e529a04d6 226 SUPERFAMILY SSF52540 15 218 1.66E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08105 c4ff6cb7926f733e52ab1f8e529a04d6 226 Gene3D G3DSA:3.40.50.300 14 218 1.5E-58 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 SUPERFAMILY SSF52317 1 188 1.76E-57 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.3E-13 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.3E-13 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.3E-13 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 Pfam PF00117 Glutamine amidotransferase class-I 4 185 1.2E-57 T 15-10-2018 IPR017926 Glutamine amidotransferase C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 Gene3D G3DSA:3.40.50.880 1 190 5.2E-63 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.8E-35 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.8E-35 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00097 Anthranilate synthase component II signature 164 177 4.8E-35 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.8E-35 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.8E-35 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.8E-35 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.9E-89 T 15-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.7E-7 T 15-10-2018 C2I28_08485 a709637c0508b56e3fa39b6a0dac5300 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.7E-7 T 15-10-2018 C2I28_01660 df08e097830ac1fc78e74012a104e560 165 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 139 7.0E-54 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_01660 df08e097830ac1fc78e74012a104e560 165 Gene3D G3DSA:2.70.70.10 6 164 1.7E-62 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_01660 df08e097830ac1fc78e74012a104e560 165 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 79 91 - T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_01660 df08e097830ac1fc78e74012a104e560 165 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 17 137 6.0E-47 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_01660 df08e097830ac1fc78e74012a104e560 165 SUPERFAMILY SSF51261 5 158 3.14E-57 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_04000 0cdcc64e248cf2946b7c3aac6b060d42 61 Pfam PF14038 YqzE-like protein 2 55 9.4E-32 T 15-10-2018 IPR025622 YqzE-like protein C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 253 5.8E-28 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 SUPERFAMILY SSF56784 2 284 7.38E-66 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 280 3.0E-62 T 15-10-2018 C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 Gene3D G3DSA:3.40.50.1000 2 277 9.0E-90 T 15-10-2018 IPR023214 HAD superfamily C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 ProSitePatterns PS01229 Hypothetical cof family signature 2. 234 256 - T 15-10-2018 C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 Gene3D G3DSA:3.30.1240.10 82 209 9.0E-90 T 15-10-2018 C2I28_25480 1e1fcf903c99b17feacd03eed3cae024 291 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 280 7.5E-59 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 Gene3D G3DSA:3.40.50.720 1 182 3.4E-70 T 15-10-2018 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 SUPERFAMILY SSF51735 3 177 1.71E-58 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 179 319 5.8E-55 T 15-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 172 196 2.5E-46 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 197 221 2.5E-46 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 2.5E-46 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.5E-46 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 237 254 2.5E-46 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 131 151 2.5E-46 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 SUPERFAMILY SSF48179 179 331 9.52E-60 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 158 3.3E-56 T 15-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 PIRSF PIRSF000114 1 331 4.0E-115 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 321 39.009 T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 187 208 - T 15-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 C2I28_03260 04a3297b789254ef03e10fb99116a4d3 343 Gene3D G3DSA:1.10.1040.10 183 326 1.5E-53 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 339 482 8.2E-30 T 15-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 Gene3D G3DSA:2.115.10.20 2 348 5.1E-134 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 30 333 7.3E-111 T 15-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 Gene3D G3DSA:2.60.120.560 349 484 1.1E-34 T 15-10-2018 C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 SUPERFAMILY SSF49899 333 487 1.03E-33 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 SUPERFAMILY SSF75005 21 334 1.15E-120 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 18 458 2.8E-155 T 15-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I28_15890 1ed9c9d8fc60122a500c96ce11087cbe 488 SMART SM00640 30 447 6.6E-160 T 15-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SMART SM00797 471 758 8.1E-146 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SMART SM00796 797 1030 1.7E-106 T 15-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Pfam PF00364 Biotin-requiring enzyme 1136 1195 2.6E-15 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 799 1019 7.7E-46 T 15-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF160467 800 890 1.96E-14 T 15-10-2018 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 472 741 1.4E-80 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF50891 622 748 1.67E-26 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF56059 83 352 3.18E-62 T 15-10-2018 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF52440 1 112 2.09E-46 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF50891 914 1046 3.41E-26 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF51230 1119 1195 1.44E-19 T 15-10-2018 IPR011053 Single hybrid motif C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 317 5.7E-62 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Gene3D G3DSA:3.30.1360.40 785 875 9.9E-22 T 15-10-2018 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 448 762 8.1E-83 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SUPERFAMILY SSF51246 330 442 1.67E-31 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.5E-44 T 15-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Gene3D G3DSA:2.40.100.10 621 776 4.5E-53 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 SMART SM00878 336 440 1.7E-38 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Pfam PF02785 Biotin carboxylase C-terminal domain 336 440 2.3E-29 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Gene3D G3DSA:2.40.50.100 1121 1195 1.2E-21 T 15-10-2018 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1195 0.0 T 15-10-2018 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Gene3D G3DSA:3.30.470.130 1 445 5.4E-179 T 15-10-2018 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_13025 8add41852191946b03d6d62f083c1b51 1203 Gene3D G3DSA:2.40.100.10 880 1103 6.9E-96 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 SUPERFAMILY SSF88659 175 258 2.43E-16 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 SUPERFAMILY SSF88659 114 190 4.05E-16 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 Gene3D G3DSA:1.10.10.10 111 164 1.4E-12 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.9E-155 T 15-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 2.7E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 2.7E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 2.7E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 2.7E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 2.7E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 Pfam PF04542 Sigma-70 region 2 42 110 3.0E-17 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 SUPERFAMILY SSF88946 6 110 1.83E-33 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 Pfam PF04545 Sigma-70, region 4 207 253 6.8E-13 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 PIRSF PIRSF000770 15 259 8.1E-33 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 Gene3D G3DSA:1.10.601.10 11 110 5.7E-27 T 15-10-2018 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 256 5.2E-35 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.7E-82 T 15-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 Pfam PF04539 Sigma-70 region 3 124 173 1.8E-6 T 15-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I28_02920 db49fc243a058efe767af5a49aadcf34 259 Gene3D G3DSA:1.10.10.10 185 259 7.8E-10 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12215 eac5acf6bd679c7a5354dce861fc8a6d 199 SUPERFAMILY SSF51182 42 156 6.79E-17 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_12215 eac5acf6bd679c7a5354dce861fc8a6d 199 Pfam PF07883 Cupin domain 93 138 2.4E-7 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_12215 eac5acf6bd679c7a5354dce861fc8a6d 199 Gene3D G3DSA:2.60.120.10 77 162 2.6E-11 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_12215 eac5acf6bd679c7a5354dce861fc8a6d 199 PIRSF PIRSF019307 32 199 7.5E-62 T 15-10-2018 IPR014500 Uncharacterised conserved protein UCP019307, cupin-type C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 SUPERFAMILY SSF51735 5 187 1.18E-56 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 SUPERFAMILY SSF48179 190 290 6.97E-25 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 PIRSF PIRSF000105 1 293 2.4E-95 T 15-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 1.9E-28 T 15-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 Gene3D G3DSA:3.40.50.720 1 186 1.4E-66 T 15-10-2018 C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 185 1.8E-61 T 15-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_17230 0d3319f4b69b295539bd9431eb0ccdf1 293 Gene3D G3DSA:1.10.1040.10 192 293 5.5E-32 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_08665 b5df214f34165a609d1712c5da235f67 156 Gene3D G3DSA:1.10.455.10 2 156 3.1E-63 T 15-10-2018 IPR036823 Ribosomal protein S7 domain superfamily C2I28_08665 b5df214f34165a609d1712c5da235f67 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.465 T 15-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 C2I28_08665 b5df214f34165a609d1712c5da235f67 156 SUPERFAMILY SSF47973 1 149 6.02E-60 T 15-10-2018 IPR036823 Ribosomal protein S7 domain superfamily C2I28_08665 b5df214f34165a609d1712c5da235f67 156 PIRSF PIRSF002122 5 156 4.1E-59 T 15-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 C2I28_08665 b5df214f34165a609d1712c5da235f67 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 9.2E-70 T 15-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 C2I28_08665 b5df214f34165a609d1712c5da235f67 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.8E-65 T 15-10-2018 IPR023798 Ribosomal protein S7 domain C2I28_08665 b5df214f34165a609d1712c5da235f67 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 15-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_03850 34b2e600eada04e4ed6822790127827d 446 Pfam PF02601 Exonuclease VII, large subunit 125 438 7.3E-105 T 15-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 C2I28_03850 34b2e600eada04e4ed6822790127827d 446 Pfam PF13742 OB-fold nucleic acid binding domain 7 102 6.6E-32 T 15-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 C2I28_03850 34b2e600eada04e4ed6822790127827d 446 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 441 29.741 T 15-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 C2I28_03850 34b2e600eada04e4ed6822790127827d 446 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 356 8.3E-143 T 15-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 C2I28_05695 bcf146eb1539731c206e6043b501f665 105 Gene3D G3DSA:3.40.30.10 1 102 1.2E-22 T 15-10-2018 C2I28_05695 bcf146eb1539731c206e6043b501f665 105 SUPERFAMILY SSF52833 5 101 2.42E-24 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_05695 bcf146eb1539731c206e6043b501f665 105 Pfam PF00085 Thioredoxin 6 101 6.7E-15 T 15-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I28_18250 e69c8d8a9b6d58a530a685f71a55c962 205 Pfam PF05908 Poly-gamma-glutamate hydrolase 6 197 2.8E-65 T 15-10-2018 IPR008585 Poly-gamma-glutamate hydrolase C2I28_18250 e69c8d8a9b6d58a530a685f71a55c962 205 Gene3D G3DSA:3.40.630.100 1 204 3.7E-70 T 15-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily C2I28_13140 47df79f27ea56ffe3cc7e45f4bc706c8 398 SMART SM00854 65 306 9.2E-92 T 15-10-2018 IPR019079 Capsule synthesis protein, CapA C2I28_13140 47df79f27ea56ffe3cc7e45f4bc706c8 398 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 65 306 2.5E-76 T 15-10-2018 IPR019079 Capsule synthesis protein, CapA C2I28_13140 47df79f27ea56ffe3cc7e45f4bc706c8 398 SUPERFAMILY SSF56300 64 323 1.8E-40 T 15-10-2018 C2I28_13140 47df79f27ea56ffe3cc7e45f4bc706c8 398 Gene3D G3DSA:3.60.21.10 125 353 1.0E-9 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_02190 c992a266244c9029381cea327bc0c21e 241 Gene3D G3DSA:3.40.50.720 1 241 2.8E-68 T 15-10-2018 C2I28_02190 c992a266244c9029381cea327bc0c21e 241 SUPERFAMILY SSF51735 3 241 2.36E-68 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_02190 c992a266244c9029381cea327bc0c21e 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 239 5.8E-49 T 15-10-2018 C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 7.9E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 7.9E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 7.9E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.0E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.0E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.0E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.0E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 5.0E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02190 c992a266244c9029381cea327bc0c21e 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 5.0E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23915 751a656ff87f9f0f4164c923e19683a2 137 Pfam PF03965 Penicillinase repressor 18 130 7.1E-24 T 15-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 C2I28_23915 751a656ff87f9f0f4164c923e19683a2 137 Gene3D G3DSA:1.10.10.10 17 92 3.2E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23915 751a656ff87f9f0f4164c923e19683a2 137 PIRSF PIRSF019455 14 137 3.5E-22 T 15-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 C2I28_23915 751a656ff87f9f0f4164c923e19683a2 137 SUPERFAMILY SSF46785 18 134 1.9E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 SUPERFAMILY SSF51366 19 267 9.89E-70 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 295 5.6E-158 T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 PIRSF PIRSF029271 1 295 1.7E-152 T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 Gene3D G3DSA:3.20.20.70 1 295 7.9E-148 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 53.909 T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08085 7f94b6ef3cf1cfd06dcf52963723df43 295 Pfam PF01680 SOR/SNZ family 9 213 9.8E-106 T 15-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 SUPERFAMILY SSF46785 18 110 9.98E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 1.1E-22 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 1.1E-22 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 1.1E-22 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 1.1E-22 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 57 75 - T 15-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 SMART SM00418 33 112 5.0E-29 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 Pfam PF01022 Bacterial regulatory protein, arsR family 40 87 4.3E-14 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23785 2d8192f7f79aa56d30e7b8775e61e807 119 Gene3D G3DSA:1.10.10.10 2 119 2.8E-35 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05350 f7beb7a5b607a82c92f93491b9d552b2 126 SUPERFAMILY SSF56276 2 113 7.85E-40 T 15-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 C2I28_05350 f7beb7a5b607a82c92f93491b9d552b2 126 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 31.289 T 15-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I28_05350 f7beb7a5b607a82c92f93491b9d552b2 126 Gene3D G3DSA:3.30.160.750 63 125 8.2E-18 T 15-10-2018 C2I28_05350 f7beb7a5b607a82c92f93491b9d552b2 126 Gene3D G3DSA:3.30.360.110 1 62 4.7E-26 T 15-10-2018 C2I28_05350 f7beb7a5b607a82c92f93491b9d552b2 126 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 1.3E-40 T 15-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I28_05350 f7beb7a5b607a82c92f93491b9d552b2 126 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 2.0E-36 T 15-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 SUPERFAMILY SSF51726 397 757 6.8E-110 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 314 2.3E-121 T 15-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 Gene3D G3DSA:3.20.20.210 8 525 0.0 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 Gene3D G3DSA:3.20.20.210 390 757 0.0 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 759 34.393 T 15-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 PIRSF PIRSF000382 3 763 0.0 T 15-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 432 754 1.4E-145 T 15-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 SUPERFAMILY SSF51726 7 392 7.46E-101 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_25545 e3ba24c07c2a4cab9732345a6a7c48f5 764 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 758 0.0 T 15-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I28_26475 7bd037ac742f7a73eb88d9e883eacc91 213 Gene3D G3DSA:1.20.1260.10 44 212 3.6E-10 T 15-10-2018 IPR012347 Ferritin-like C2I28_26475 7bd037ac742f7a73eb88d9e883eacc91 213 SUPERFAMILY SSF47240 44 205 2.67E-11 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 15-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 Gene3D G3DSA:3.30.860.10 1 92 9.1E-40 T 15-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.1E-47 T 15-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 SUPERFAMILY SSF54570 3 84 9.55E-35 T 15-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.4E-24 T 15-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.4E-24 T 15-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.4E-24 T 15-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 PIRSF PIRSF002144 1 92 2.9E-32 T 15-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.374 T 15-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08705 f343c8ad996e7dde163b0c7497ccbcbe 92 Pfam PF00203 Ribosomal protein S19 3 83 1.5E-35 T 15-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_14595 17bc511f142a9310d33a0c337c9ef11d 203 Gene3D G3DSA:3.40.109.10 1 203 8.2E-56 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_14595 17bc511f142a9310d33a0c337c9ef11d 203 SUPERFAMILY SSF55469 3 203 1.28E-54 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_14595 17bc511f142a9310d33a0c337c9ef11d 203 Pfam PF00881 Nitroreductase family 10 183 1.6E-31 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 SUPERFAMILY SSF51338 1 447 3.28E-29 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 Gene3D G3DSA:3.20.20.140 53 417 2.1E-151 T 15-10-2018 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 Hamap MF_01645 Allantoinase [allB]. 1 449 48.371 T 15-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 SUPERFAMILY SSF51556 54 377 1.36E-97 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 Gene3D G3DSA:2.30.40.10 4 432 2.1E-151 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 Pfam PF01979 Amidohydrolase family 50 431 1.1E-28 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 TIGRFAM TIGR03178 allantoinase: allantoinase 3 447 2.4E-165 T 15-10-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 C2I28_18085 7ba61ad8593d319349035c733d43e4ea 454 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 434 2.3E-84 T 15-10-2018 C2I28_18385 5febe5097685ce54a201367197f6b34e 321 SUPERFAMILY SSF53448 5 257 4.13E-37 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18385 5febe5097685ce54a201367197f6b34e 321 Gene3D G3DSA:3.90.550.10 2 214 2.8E-39 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18385 5febe5097685ce54a201367197f6b34e 321 Pfam PF00535 Glycosyl transferase family 2 8 168 2.2E-36 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 Gene3D G3DSA:3.40.190.10 115 214 1.4E-92 T 15-10-2018 C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 Gene3D G3DSA:1.10.8.450 247 279 1.4E-92 T 15-10-2018 C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 SUPERFAMILY SSF53850 32 257 9.7E-50 T 15-10-2018 C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 Pfam PF09084 NMT1/THI5 like 44 254 1.6E-23 T 15-10-2018 IPR015168 SsuA/THI5-like C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 Gene3D G3DSA:3.40.190.10 35 311 1.4E-92 T 15-10-2018 C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 321 1.8E-95 T 15-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 C2I28_05130 ca49af0aa3305b1cd520741c74b3e806 328 SMART SM00062 34 269 5.6E-21 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_03095 4277da542584b07f3046aafb90708eda 148 Gene3D G3DSA:1.20.1500.10 3 126 1.7E-28 T 15-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I28_03095 4277da542584b07f3046aafb90708eda 148 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 116 1.2E-19 T 15-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I28_03095 4277da542584b07f3046aafb90708eda 148 SUPERFAMILY SSF158622 4 126 1.01E-32 T 15-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 PIRSF PIRSF001438 1 310 1.7E-121 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 15-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 Gene3D G3DSA:3.40.190.10 101 201 1.3E-84 T 15-10-2018 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 Gene3D G3DSA:3.30.160.40 220 304 2.9E-30 T 15-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 1.1E-109 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 SUPERFAMILY SSF54782 219 308 2.35E-21 T 15-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 6.5E-81 T 15-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 2.0E-47 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 2.0E-47 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 2.0E-47 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 2.0E-47 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 2.0E-47 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 SUPERFAMILY SSF53850 2 218 2.89E-81 T 15-10-2018 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 39.15 T 15-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 292 6.0E-17 T 15-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04970 4afaf9466ce3d5f38231524a37d26e5d 310 Gene3D G3DSA:3.40.190.10 4 209 1.3E-84 T 15-10-2018 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 Gene3D G3DSA:3.40.50.720 1 164 1.8E-40 T 15-10-2018 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 100 1.2E-16 T 15-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 SUPERFAMILY SSF48179 163 263 1.7E-25 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 263 1.4E-67 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 SUPERFAMILY SSF51735 5 158 1.28E-28 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 PIRSF PIRSF000193 3 267 2.0E-65 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 266 21.659 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 263 9.9E-30 T 15-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_17875 3ce4fd93a77676031f53b1d77f22578e 267 Gene3D G3DSA:1.10.3730.10 165 265 1.8E-29 T 15-10-2018 C2I28_22750 44f28b50a315e14fa5f0ae8850fc9f34 320 Gene3D G3DSA:2.40.260.10 24 238 1.4E-36 T 15-10-2018 IPR023365 Sortase domain superfamily C2I28_22750 44f28b50a315e14fa5f0ae8850fc9f34 320 SUPERFAMILY SSF49265 237 318 4.62E-5 T 15-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I28_22750 44f28b50a315e14fa5f0ae8850fc9f34 320 Pfam PF04203 Sortase family 87 225 2.4E-21 T 15-10-2018 IPR005754 Sortase family C2I28_22750 44f28b50a315e14fa5f0ae8850fc9f34 320 Gene3D G3DSA:2.60.40.10 239 320 1.6E-7 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_22750 44f28b50a315e14fa5f0ae8850fc9f34 320 SUPERFAMILY SSF63817 84 225 4.05E-19 T 15-10-2018 IPR023365 Sortase domain superfamily C2I28_02305 84765b2f8c09f19b622b1f9a19c1be82 305 SUPERFAMILY SSF55120 2 226 4.96E-82 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02305 84765b2f8c09f19b622b1f9a19c1be82 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 302 19.425 T 15-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02305 84765b2f8c09f19b622b1f9a19c1be82 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 2.2E-59 T 15-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 C2I28_02305 84765b2f8c09f19b622b1f9a19c1be82 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 4.0E-84 T 15-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02305 84765b2f8c09f19b622b1f9a19c1be82 305 Gene3D G3DSA:3.30.2350.10 1 244 2.1E-92 T 15-10-2018 C2I28_02305 84765b2f8c09f19b622b1f9a19c1be82 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 3.2E-12 T 15-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Gene3D G3DSA:3.30.450.20 33 192 6.0E-6 T 15-10-2018 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Pfam PF00672 HAMP domain 222 271 3.0E-6 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 SMART SM00388 324 390 1.5E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 SUPERFAMILY SSF55874 381 535 1.44E-36 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Gene3D G3DSA:1.10.287.130 309 386 1.1E-20 T 15-10-2018 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 SMART SM00304 222 274 4.6E-9 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Pfam PF00512 His Kinase A (phospho-acceptor) domain 326 388 1.5E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Gene3D G3DSA:1.10.287.130 221 277 6.9E-7 T 15-10-2018 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 SMART SM00387 432 538 1.8E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 SUPERFAMILY SSF158472 222 272 5.23E-7 T 15-10-2018 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 SUPERFAMILY SSF47384 311 389 2.55E-15 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 535 2.4E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 Gene3D G3DSA:3.30.565.10 387 536 7.5E-37 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01830 41c5ca831abeecd9644d723ac658ee32 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 535 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 SUPERFAMILY SSF53223 6 158 2.95E-56 T 15-10-2018 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 PRINTS PR00072 Malic enzyme signature 77 99 7.4E-9 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 PRINTS PR00072 Malic enzyme signature 156 172 7.4E-9 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 PRINTS PR00072 Malic enzyme signature 187 203 7.4E-9 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 15-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 SUPERFAMILY SSF51735 160 401 6.77E-83 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 SMART SM01274 15 148 3.6E-85 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 Gene3D G3DSA:3.40.50.720 158 410 1.1E-86 T 15-10-2018 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 SMART SM00919 160 384 3.2E-133 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 Gene3D G3DSA:3.40.50.10380 1 157 9.3E-76 T 15-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 PIRSF PIRSF000106 35 409 4.9E-84 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 4.7E-30 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_23560 4c8d504e863bef950fa4026ef04b20b6 410 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 2.8E-24 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_18185 1ad320ba5163bd822e2dbd120048de63 619 Gene3D G3DSA:3.40.80.10 252 414 5.0E-40 T 15-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I28_18185 1ad320ba5163bd822e2dbd120048de63 619 SUPERFAMILY SSF55846 264 407 2.62E-35 T 15-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I28_18185 1ad320ba5163bd822e2dbd120048de63 619 SUPERFAMILY SSF53955 24 178 6.06E-8 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_18185 1ad320ba5163bd822e2dbd120048de63 619 SMART SM00644 259 395 1.2E-41 T 15-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I28_18185 1ad320ba5163bd822e2dbd120048de63 619 Gene3D G3DSA:1.10.530.10 50 207 8.7E-15 T 15-10-2018 C2I28_18185 1ad320ba5163bd822e2dbd120048de63 619 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 266 396 5.2E-27 T 15-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 C2I28_02005 3f854f17cfc1f127f9d867abe0f0dd32 222 SUPERFAMILY SSF53041 3 148 9.81E-24 T 15-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 C2I28_02005 3f854f17cfc1f127f9d867abe0f0dd32 222 SMART SM00857 3 149 1.7E-31 T 15-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I28_02005 3f854f17cfc1f127f9d867abe0f0dd32 222 Pfam PF00239 Resolvase, N terminal domain 3 147 1.6E-25 T 15-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I28_02005 3f854f17cfc1f127f9d867abe0f0dd32 222 Gene3D G3DSA:3.40.50.1390 1 156 1.6E-26 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:3.30.70.1320 132 319 7.4E-263 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82693 145 308 1.36E-7 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:1.20.1640.10 11 495 7.4E-263 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:3.30.70.1440 641 835 7.4E-263 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82714 693 774 6.02E-9 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:3.30.70.1430 543 640 7.4E-263 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Pfam PF00873 AcrB/AcrD/AcrF family 5 996 1.2E-212 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82866 287 483 3.14E-40 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:3.30.2090.10 692 778 7.4E-263 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82714 180 262 1.96E-10 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82693 541 626 7.85E-7 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 350 371 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 433 456 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 528 545 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 458 481 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 323 346 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 PRINTS PR00702 Acriflavin resistance protein family signature 378 402 1.0E-49 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:1.20.1640.10 496 993 7.4E-263 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:3.30.70.1430 41 786 7.4E-263 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82693 41 121 4.01E-18 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 SUPERFAMILY SSF82866 778 1001 1.96E-45 T 15-10-2018 C2I28_23685 bd49bb63321a897e5da2f35a3bb08e67 1012 Gene3D G3DSA:3.30.2090.10 174 266 7.4E-263 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Pfam PF14492 Elongation Factor G, domain II 402 475 3.5E-35 T 15-10-2018 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SMART SM00838 598 685 7.7E-59 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_08670 189745ebc2a26efffa8c563a26443397 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 15-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 3.1E-70 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Gene3D G3DSA:3.30.70.240 602 672 7.5E-95 T 15-10-2018 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Gene3D G3DSA:3.40.50.300 1 292 5.5E-114 T 15-10-2018 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SUPERFAMILY SSF52540 6 280 5.9E-112 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Gene3D G3DSA:3.30.230.10 482 685 7.5E-95 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Pfam PF03764 Elongation factor G, domain IV 477 595 2.3E-48 T 15-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Gene3D G3DSA:2.40.30.10 293 403 1.3E-46 T 15-10-2018 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 15-10-2018 IPR031157 Tr-type G domain, conserved site C2I28_08670 189745ebc2a26efffa8c563a26443397 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 3.4E-44 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SMART SM00889 478 596 1.2E-74 T 15-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 2.5E-16 T 15-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Pfam PF00679 Elongation factor G C-terminus 599 684 2.6E-31 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SUPERFAMILY SSF54980 601 688 8.15E-31 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 113.642 T 15-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SUPERFAMILY SSF50447 263 402 1.11E-36 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_08670 189745ebc2a26efffa8c563a26443397 692 Gene3D G3DSA:3.30.70.870 404 481 6.8E-33 T 15-10-2018 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SUPERFAMILY SSF54980 400 478 9.35E-26 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_08670 189745ebc2a26efffa8c563a26443397 692 SUPERFAMILY SSF54211 477 597 1.87E-44 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08670 189745ebc2a26efffa8c563a26443397 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.4E-17 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 5.4E-17 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 5.4E-17 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 5.4E-17 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08670 189745ebc2a26efffa8c563a26443397 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.4E-17 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_22025 2cf41dac6a16aa2458752070379ac037 115 Pfam PF05656 Protein of unknown function (DUF805) 13 110 7.6E-33 T 15-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 C2I28_12640 c158b712b7c8c9f4d442e398d013c06b 121 Pfam PF01638 HxlR-like helix-turn-helix 18 106 1.5E-37 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_12640 c158b712b7c8c9f4d442e398d013c06b 121 Gene3D G3DSA:1.10.10.10 2 118 4.0E-39 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12640 c158b712b7c8c9f4d442e398d013c06b 121 SUPERFAMILY SSF46785 7 108 5.7E-32 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_11645 daf055d938de31d343b427669660ffdf 312 SUPERFAMILY SSF53901 4 310 7.07E-72 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_11645 daf055d938de31d343b427669660ffdf 312 Gene3D G3DSA:3.40.47.10 1 312 3.1E-132 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_11645 daf055d938de31d343b427669660ffdf 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 310 71.108 T 15-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_11645 daf055d938de31d343b427669660ffdf 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 310 7.5E-35 T 15-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_11645 daf055d938de31d343b427669660ffdf 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 310 7.6E-134 T 15-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_11645 daf055d938de31d343b427669660ffdf 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 2.7E-31 T 15-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 Gene3D G3DSA:3.40.710.10 330 676 2.0E-219 T 15-10-2018 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 Pfam PF00905 Penicillin binding protein transpeptidase domain 363 692 1.3E-68 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 Gene3D G3DSA:2.20.70.40 299 321 2.0E-219 T 15-10-2018 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 SUPERFAMILY SSF56519 55 330 1.31E-31 T 15-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 316 1.6E-35 T 15-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 Gene3D G3DSA:1.10.10.1230 86 205 2.0E-219 T 15-10-2018 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 Gene3D G3DSA:3.90.1310.30 61 587 2.0E-219 T 15-10-2018 C2I28_04120 08aa1dfc0372a5aaa10dbc29b057db81 725 SUPERFAMILY SSF56601 331 696 1.79E-64 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 Gene3D G3DSA:3.40.50.720 7 315 1.7E-103 T 15-10-2018 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 113 127 1.8E-6 T 15-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 252 267 1.8E-6 T 15-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 2 15 1.8E-6 T 15-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 308 324 1.8E-6 T 15-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 SUPERFAMILY SSF55347 131 317 1.41E-33 T 15-10-2018 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 238 9.4E-7 T 15-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 1.5E-34 T 15-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 Gene3D G3DSA:3.30.360.10 128 336 1.7E-103 T 15-10-2018 C2I28_18570 bf6a96642e15a26b2e82536907505d93 341 SUPERFAMILY SSF51735 3 155 4.68E-59 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 Gene3D G3DSA:3.40.50.720 1 258 3.2E-81 T 15-10-2018 C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 SUPERFAMILY SSF51735 3 257 7.55E-84 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 9.0E-66 T 15-10-2018 C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.9E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.9E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.9E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.9E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.9E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.9E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.9E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19060 e006c7993fafbed5917017e6d91d711e 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 1.7E-110 T 15-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 C2I28_14820 6f8371c890342165ffbbeb64f91e9f60 211 PIRSF PIRSF021332 1 209 8.8E-90 T 15-10-2018 IPR009403 Protein of unknown function UPF0637 C2I28_14820 6f8371c890342165ffbbeb64f91e9f60 211 Hamap MF_01851 UPF0637 protein . 5 205 39.163 T 15-10-2018 IPR009403 Protein of unknown function UPF0637 C2I28_14820 6f8371c890342165ffbbeb64f91e9f60 211 Gene3D G3DSA:3.30.930.20 2 211 3.4E-91 T 15-10-2018 C2I28_14820 6f8371c890342165ffbbeb64f91e9f60 211 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 5.5E-87 T 15-10-2018 IPR009403 Protein of unknown function UPF0637 C2I28_14820 6f8371c890342165ffbbeb64f91e9f60 211 SUPERFAMILY SSF142913 3 208 2.38E-84 T 15-10-2018 C2I28_02680 06c49e5b9bf71b6b0966dda7cbb970bc 334 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 333 152.958 T 15-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 C2I28_02680 06c49e5b9bf71b6b0966dda7cbb970bc 334 PIRSF PIRSF002465 1 332 8.1E-132 T 15-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 C2I28_02680 06c49e5b9bf71b6b0966dda7cbb970bc 334 Gene3D G3DSA:3.40.718.10 1 334 1.4E-140 T 15-10-2018 C2I28_02680 06c49e5b9bf71b6b0966dda7cbb970bc 334 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 330 7.0E-139 T 15-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 C2I28_02680 06c49e5b9bf71b6b0966dda7cbb970bc 334 SUPERFAMILY SSF53659 1 328 1.32E-105 T 15-10-2018 C2I28_02680 06c49e5b9bf71b6b0966dda7cbb970bc 334 Pfam PF02504 Fatty acid synthesis protein 1 318 8.2E-128 T 15-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 C2I28_24595 15971d1cc137328716875fb4d817132a 74 Pfam PF01206 Sulfurtransferase TusA 5 73 1.6E-24 T 15-10-2018 IPR001455 TusA-like domain C2I28_24595 15971d1cc137328716875fb4d817132a 74 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 15-10-2018 IPR001455 TusA-like domain C2I28_24595 15971d1cc137328716875fb4d817132a 74 Gene3D G3DSA:3.30.110.40 1 74 3.9E-30 T 15-10-2018 IPR036868 TusA-like domain superfamily C2I28_24595 15971d1cc137328716875fb4d817132a 74 SUPERFAMILY SSF64307 4 74 2.09E-25 T 15-10-2018 IPR036868 TusA-like domain superfamily C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 162 190 - T 15-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 101 133 5.4E-7 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 154 187 2.3E-7 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 SUPERFAMILY SSF51161 2 205 4.16E-47 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 Gene3D G3DSA:2.160.10.10 82 207 3.1E-29 T 15-10-2018 C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 Gene3D G3DSA:3.40.50.20 1 81 1.4E-16 T 15-10-2018 C2I28_18885 65498ea81f96ca9ebb0811892705f368 207 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 2 202 1.9E-66 T 15-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 Gene3D G3DSA:3.50.30.10 731 836 1.6E-32 T 15-10-2018 C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 SUPERFAMILY SSF56059 13 297 1.08E-76 T 15-10-2018 C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 Gene3D G3DSA:3.30.470.20 163 309 8.8E-42 T 15-10-2018 C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 SUPERFAMILY SSF52009 728 833 4.32E-28 T 15-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 14 300 2.3E-81 T 15-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 Pfam PF00391 PEP-utilising enzyme, mobile domain 758 830 1.7E-22 T 15-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I28_16160 919aab2ab0f1580264d4a0e5709be71f 837 Gene3D G3DSA:3.30.1490.20 1 162 3.2E-41 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 PRINTS PR00207 Flagellin signature 74 93 1.0E-22 T 15-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 PRINTS PR00207 Flagellin signature 35 52 1.0E-22 T 15-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 PRINTS PR00207 Flagellin signature 109 132 1.0E-22 T 15-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 Gene3D G3DSA:1.10.8.410 221 270 2.7E-27 T 15-10-2018 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 Gene3D G3DSA:1.20.1330.10 48 220 8.4E-60 T 15-10-2018 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 Pfam PF00700 Bacterial flagellin C-terminal helical region 185 269 2.0E-28 T 15-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 SUPERFAMILY SSF64518 1 270 1.29E-89 T 15-10-2018 C2I28_13580 7a566cde886ad73f2c023c8b695a45d2 270 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 7.7E-41 T 15-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I28_06445 18a49671912f376b67c7949e191a60fb 333 SUPERFAMILY SSF56112 4 314 2.24E-15 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_06445 18a49671912f376b67c7949e191a60fb 333 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 3 313 7.8E-113 T 15-10-2018 IPR014254 Spore coat protein YutH C2I28_06445 18a49671912f376b67c7949e191a60fb 333 Gene3D G3DSA:3.90.1200.10 98 313 1.1E-27 T 15-10-2018 C2I28_18970 eebe86feb78de6689b0216f23e26f30c 397 SUPERFAMILY SSF81301 129 246 9.16E-6 T 15-10-2018 C2I28_18970 eebe86feb78de6689b0216f23e26f30c 397 Pfam PF14907 Uncharacterised nucleotidyltransferase 39 287 1.4E-55 T 15-10-2018 IPR039498 Uncharacterised nucleotidyltransferase C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Gene3D G3DSA:3.10.350.10 86 136 7.2E-16 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Gene3D G3DSA:3.10.350.10 20 84 2.3E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Pfam PF01476 LysM domain 32 74 5.2E-11 T 15-10-2018 IPR018392 LysM domain C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Pfam PF01476 LysM domain 90 131 2.9E-11 T 15-10-2018 IPR018392 LysM domain C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Gene3D G3DSA:2.40.10.420 235 268 4.7E-12 T 15-10-2018 C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 SUPERFAMILY SSF54106 89 131 2.22E-10 T 15-10-2018 C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 SMART SM00257 31 74 5.0E-14 T 15-10-2018 IPR018392 LysM domain C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 SMART SM00257 89 132 3.6E-12 T 15-10-2018 IPR018392 LysM domain C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Gene3D G3DSA:1.10.10.2520 149 232 4.7E-29 T 15-10-2018 C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 Pfam PF07486 Cell Wall Hydrolase 165 266 1.0E-24 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_24035 5dbab411320d5bf44c3a088d68a3cecc 268 SUPERFAMILY SSF54106 31 74 3.4E-10 T 15-10-2018 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 SUPERFAMILY SSF47005 118 161 2.09E-11 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 Gene3D G3DSA:3.30.559.10 169 405 3.9E-82 T 15-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 SUPERFAMILY SSF51230 1 90 5.23E-23 T 15-10-2018 IPR011053 Single hybrid motif C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 Pfam PF02817 e3 binding domain 123 158 1.0E-13 T 15-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 SUPERFAMILY SSF52777 181 408 3.65E-77 T 15-10-2018 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 180 407 2.8E-79 T 15-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 Gene3D G3DSA:2.40.50.100 1 118 5.0E-26 T 15-10-2018 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 Gene3D G3DSA:4.10.320.10 119 168 3.2E-17 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_17365 2f2cd44f8621ccadfdb99e0d21c85f70 408 Pfam PF00364 Biotin-requiring enzyme 4 75 2.8E-17 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_02090 253cd8131b148d0e098c23e961279c79 74 SUPERFAMILY SSF50182 6 65 8.18E-25 T 15-10-2018 IPR010920 LSM domain superfamily C2I28_02090 253cd8131b148d0e098c23e961279c79 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 2.6E-33 T 15-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I28_02090 253cd8131b148d0e098c23e961279c79 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 30.651 T 15-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I28_02090 253cd8131b148d0e098c23e961279c79 74 Pfam PF17209 Hfq protein 7 69 2.8E-33 T 15-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 C2I28_02090 253cd8131b148d0e098c23e961279c79 74 Gene3D G3DSA:2.30.30.100 1 74 6.2E-35 T 15-10-2018 C2I28_16540 81c7fc70db63f79b2df51e31fa121154 295 SUPERFAMILY SSF53850 88 289 3.1E-30 T 15-10-2018 C2I28_16540 81c7fc70db63f79b2df51e31fa121154 295 Gene3D G3DSA:3.40.190.290 90 293 5.1E-35 T 15-10-2018 C2I28_16540 81c7fc70db63f79b2df51e31fa121154 295 SUPERFAMILY SSF46785 2 99 5.99E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16540 81c7fc70db63f79b2df51e31fa121154 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.9E-18 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_16540 81c7fc70db63f79b2df51e31fa121154 295 Gene3D G3DSA:1.10.10.10 1 89 3.3E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16540 81c7fc70db63f79b2df51e31fa121154 295 Pfam PF03466 LysR substrate binding domain 88 286 3.4E-35 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.5E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.5E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.5E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 Gene3D G3DSA:3.40.50.720 1 252 1.3E-80 T 15-10-2018 C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.8E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.8E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.8E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.8E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 8.8E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.8E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 7.4E-59 T 15-10-2018 C2I28_14655 48c066ac05a0c5d78992a821a6fb534d 254 SUPERFAMILY SSF51735 2 249 1.37E-82 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06290 fa2040126fdbb1b725847a4866880584 133 SUPERFAMILY SSF50249 4 87 1.49E-23 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_06290 fa2040126fdbb1b725847a4866880584 133 Pfam PF00575 S1 RNA binding domain 3 76 6.9E-20 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_06290 fa2040126fdbb1b725847a4866880584 133 Gene3D G3DSA:2.40.50.140 1 87 3.9E-31 T 15-10-2018 C2I28_06290 fa2040126fdbb1b725847a4866880584 133 SMART SM00316 5 76 2.3E-24 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_01015 68b085f75b901c3e0bb76bcccb2e69e6 224 SUPERFAMILY SSF47090 25 91 4.45E-18 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_01015 68b085f75b901c3e0bb76bcccb2e69e6 224 SUPERFAMILY SSF54001 102 221 1.15E-42 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_01015 68b085f75b901c3e0bb76bcccb2e69e6 224 Pfam PF01471 Putative peptidoglycan binding domain 36 91 1.0E-13 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_01015 68b085f75b901c3e0bb76bcccb2e69e6 224 Pfam PF00877 NlpC/P60 family 117 219 4.6E-32 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_01015 68b085f75b901c3e0bb76bcccb2e69e6 224 Gene3D G3DSA:3.90.1720.10 99 224 9.6E-46 T 15-10-2018 C2I28_01015 68b085f75b901c3e0bb76bcccb2e69e6 224 Gene3D G3DSA:1.10.101.10 22 98 1.0E-18 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_17285 a2d4edd713ae9e58448731e9ed743107 140 SMART SM00116 76 123 1.6E-7 T 15-10-2018 IPR000644 CBS domain C2I28_17285 a2d4edd713ae9e58448731e9ed743107 140 SMART SM00116 11 58 1.3E-5 T 15-10-2018 IPR000644 CBS domain C2I28_17285 a2d4edd713ae9e58448731e9ed743107 140 SUPERFAMILY SSF54631 2 121 1.01E-32 T 15-10-2018 C2I28_17285 a2d4edd713ae9e58448731e9ed743107 140 Gene3D G3DSA:3.10.580.10 1 123 9.6E-39 T 15-10-2018 C2I28_17285 a2d4edd713ae9e58448731e9ed743107 140 Pfam PF00571 CBS domain 4 54 2.0E-11 T 15-10-2018 IPR000644 CBS domain C2I28_17285 a2d4edd713ae9e58448731e9ed743107 140 Pfam PF00571 CBS domain 71 120 1.5E-11 T 15-10-2018 IPR000644 CBS domain C2I28_01085 3e1a69034655ad4c5a4a970104ab5232 165 SUPERFAMILY SSF48452 11 152 6.83E-11 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_01085 3e1a69034655ad4c5a4a970104ab5232 165 Gene3D G3DSA:1.25.40.10 6 162 4.8E-13 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Gene3D G3DSA:3.30.1360.10 17 221 1.9E-91 T 15-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 56 152 2.4E-25 T 15-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 SUPERFAMILY SSF56553 50 171 1.24E-44 T 15-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 1.0E-25 T 15-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.751 T 15-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 SUPERFAMILY SSF47789 247 313 7.85E-25 T 15-10-2018 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 SUPERFAMILY SSF55257 5 230 1.96E-33 T 15-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.9E-29 T 15-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 SMART SM00662 20 227 1.5E-102 T 15-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 9.8E-25 T 15-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Gene3D G3DSA:1.10.150.20 237 314 1.5E-34 T 15-10-2018 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 Gene3D G3DSA:2.170.120.12 50 170 1.9E-91 T 15-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08820 a686880c2d1ebbbda537dabb6da8ce47 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 1.6E-127 T 15-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 SUPERFAMILY SSF53187 1 360 3.67E-42 T 15-10-2018 C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 Gene3D G3DSA:3.40.630.10 5 350 2.5E-109 T 15-10-2018 C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 Gene3D G3DSA:3.30.70.360 168 275 2.5E-109 T 15-10-2018 C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 Pfam PF01546 Peptidase family M20/M25/M40 66 359 1.5E-26 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 SUPERFAMILY SSF55031 168 260 4.45E-21 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 PIRSF PIRSF037238 1 361 2.2E-124 T 15-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase C2I28_17045 2735a12bb09668c2f1c8333cc54e7436 361 Pfam PF07687 Peptidase dimerisation domain 165 254 3.5E-18 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 Pfam PF00701 Dihydrodipicolinate synthetase family 7 298 3.2E-82 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 Gene3D G3DSA:3.20.20.70 6 299 7.4E-103 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 SMART SM01130 6 300 8.5E-96 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 PIRSF PIRSF001365 2 306 2.0E-81 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 2.4E-20 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 2.4E-20 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 2.4E-20 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 2.4E-20 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 169 - T 15-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 C2I28_25730 0fbb2922d03dd440f37eedf9fe36e5dc 309 SUPERFAMILY SSF51569 3 297 2.2E-83 T 15-10-2018 C2I28_19530 154501c358a96a1db7ed1ebf4117fe0d 201 Gene3D G3DSA:3.50.30.100 1 180 1.5E-50 T 15-10-2018 C2I28_19530 154501c358a96a1db7ed1ebf4117fe0d 201 Pfam PF03737 Aldolase/RraA 10 158 3.9E-39 T 15-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein C2I28_19530 154501c358a96a1db7ed1ebf4117fe0d 201 SUPERFAMILY SSF89562 8 169 2.62E-44 T 15-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily C2I28_09465 d84705017499959806cece5d74f49ccf 345 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 333 1.7E-142 T 15-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09465 d84705017499959806cece5d74f49ccf 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 337 1.1E-36 T 15-10-2018 IPR010918 PurM-like, C-terminal domain C2I28_09465 d84705017499959806cece5d74f49ccf 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 160 4.8E-17 T 15-10-2018 IPR016188 PurM-like, N-terminal domain C2I28_09465 d84705017499959806cece5d74f49ccf 345 SUPERFAMILY SSF55326 2 167 2.54E-50 T 15-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I28_09465 d84705017499959806cece5d74f49ccf 345 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 47.491 T 15-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09465 d84705017499959806cece5d74f49ccf 345 Gene3D G3DSA:3.30.1330.10 1 167 1.1E-68 T 15-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I28_09465 d84705017499959806cece5d74f49ccf 345 Gene3D G3DSA:3.90.650.10 168 345 1.3E-69 T 15-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I28_09465 d84705017499959806cece5d74f49ccf 345 SUPERFAMILY SSF56042 168 338 8.97E-59 T 15-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 SUPERFAMILY SSF51182 51 181 1.28E-25 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 Pfam PF01381 Helix-turn-helix 14 65 3.2E-15 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 Pfam PF07883 Cupin domain 110 175 1.1E-12 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 SMART SM00530 11 66 1.1E-14 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 Gene3D G3DSA:1.10.260.40 2 80 6.5E-20 T 15-10-2018 C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 Gene3D G3DSA:2.60.120.10 92 183 3.7E-25 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_24095 086523ead65c8ed6e0db58130a5d0841 183 SUPERFAMILY SSF47413 5 73 2.68E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_01970 038a02277af19e1d4c319838140c1542 58 Pfam PF09388 Spo0E like sporulation regulatory protein 6 46 6.5E-13 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_01970 038a02277af19e1d4c319838140c1542 58 Gene3D G3DSA:1.20.58.990 4 56 1.2E-11 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_01970 038a02277af19e1d4c319838140c1542 58 SUPERFAMILY SSF140500 3 52 8.11E-14 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 SUPERFAMILY SSF52172 5 139 3.7E-37 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 Pfam PF00072 Response regulator receiver domain 8 119 3.9E-31 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 PIRSF PIRSF006171 4 228 1.2E-82 T 15-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 Gene3D G3DSA:3.40.50.2300 2 142 4.8E-34 T 15-10-2018 C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 Pfam PF04703 FaeA-like protein 167 208 1.5E-4 T 15-10-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 SUPERFAMILY SSF46785 164 210 2.58E-5 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12360 d0636cf4ffb7ac7ea0e8b711ae69d29e 228 SMART SM00448 6 119 2.7E-33 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_23035 f036981b3444e34b503c44d5d6470896 221 Gene3D G3DSA:3.40.50.880 1 221 4.4E-54 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_23035 f036981b3444e34b503c44d5d6470896 221 SUPERFAMILY SSF52317 2 219 2.47E-47 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_23035 f036981b3444e34b503c44d5d6470896 221 Pfam PF01965 DJ-1/PfpI family 25 217 5.3E-13 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 SUPERFAMILY SSF51011 586 664 1.15E-21 T 15-10-2018 C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 Gene3D G3DSA:2.60.40.1760 56 227 2.2E-17 T 15-10-2018 C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 Pfam PF01055 Glycosyl hydrolases family 31 230 668 1.5E-77 T 15-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 Gene3D G3DSA:3.20.20.80 231 616 4.4E-95 T 15-10-2018 C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 SUPERFAMILY SSF74650 66 220 2.51E-16 T 15-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 Gene3D G3DSA:2.60.40.1180 617 664 4.8E-10 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_26045 19ce1408129bc84a8ba1446a9c6621a0 679 SUPERFAMILY SSF51445 236 584 1.11E-55 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 37 290 6.1E-112 T 15-10-2018 IPR023705 Nucleoid occlusion protein C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 Pfam PF02195 ParB-like nuclease domain 40 128 1.3E-26 T 15-10-2018 IPR003115 ParB/Sulfiredoxin C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 Gene3D G3DSA:1.10.10.2830 116 229 7.6E-35 T 15-10-2018 C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 Gene3D G3DSA:3.90.1530.30 52 115 2.2E-25 T 15-10-2018 C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 37 215 1.2E-59 T 15-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 SUPERFAMILY SSF110849 38 182 3.35E-32 T 15-10-2018 IPR036086 ParB/Sulfiredoxin superfamily C2I28_07975 aec4f7992741ef4e792aecb1577f369d 291 SMART SM00470 39 129 1.4E-34 T 15-10-2018 IPR003115 ParB/Sulfiredoxin C2I28_03025 c0b1dc10fd7f7e7518303871a06a678f 156 Gene3D G3DSA:3.40.630.30 1 155 1.4E-51 T 15-10-2018 C2I28_03025 c0b1dc10fd7f7e7518303871a06a678f 156 PIRSF PIRSF037732 1 156 6.3E-76 T 15-10-2018 IPR017274 Putative N-acetyltransferase YlbP C2I28_03025 c0b1dc10fd7f7e7518303871a06a678f 156 SUPERFAMILY SSF55729 26 142 7.67E-12 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_03025 c0b1dc10fd7f7e7518303871a06a678f 156 Hamap MF_00824 Uncharacterized N-acetyltransferase . 2 149 38.796 T 15-10-2018 IPR017274 Putative N-acetyltransferase YlbP C2I28_03025 c0b1dc10fd7f7e7518303871a06a678f 156 Pfam PF00583 Acetyltransferase (GNAT) family 34 106 2.5E-6 T 15-10-2018 IPR000182 GNAT domain C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 2.0E-27 T 15-10-2018 C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.2E-42 T 15-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 15-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.265 T 15-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 Pfam PF00312 Ribosomal protein S15 8 88 1.3E-38 T 15-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 SMART SM01387 8 88 9.6E-54 T 15-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 SUPERFAMILY SSF47060 3 89 1.44E-37 T 15-10-2018 IPR009068 S15/NS1, RNA-binding C2I28_02295 b209c0fc6bbeec66d68651bce4f3037e 89 Gene3D G3DSA:1.10.287.10 2 89 7.4E-38 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 SUPERFAMILY SSF118215 8 404 1.14E-123 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 38 53 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 1.8E-44 T 15-10-2018 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 Pfam PF00375 Sodium:dicarboxylate symporter family 8 402 3.0E-125 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 298 321 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_10410 c43819ca1d67312e6a244cc991f0d4d5 419 Gene3D G3DSA:1.10.3860.10 1 417 2.0E-134 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Pfam PF08676 MutL C terminal dimerisation domain 440 581 9.5E-48 T 15-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Gene3D G3DSA:3.30.230.10 213 325 4.7E-32 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 15-10-2018 IPR014762 DNA mismatch repair, conserved site C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 SMART SM00853 439 581 3.5E-55 T 15-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 SUPERFAMILY SSF118116 435 623 3.53E-56 T 15-10-2018 IPR037198 MutL, C-terminal domain superfamily C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 SMART SM01340 208 326 2.8E-53 T 15-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 3.6E-36 T 15-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 99 1.2E-10 T 15-10-2018 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 621 27.324 T 15-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.2E-97 T 15-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 SUPERFAMILY SSF55874 4 213 1.18E-47 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Gene3D G3DSA:3.30.1370.100 481 574 2.5E-65 T 15-10-2018 C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 SUPERFAMILY SSF54211 190 326 9.1E-36 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Gene3D G3DSA:3.30.565.10 1 212 6.8E-59 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_02100 e18010b75c0df26b5a6fc2d3de79a786 625 Gene3D G3DSA:2.30.42.20 440 623 2.5E-65 T 15-10-2018 C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 2.8E-69 T 15-10-2018 C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.2E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.2E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 7.9E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.9E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.9E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 Gene3D G3DSA:3.40.50.720 1 248 1.7E-77 T 15-10-2018 C2I28_22850 8ce2601114a53ad99c26c39ceddcf52b 249 SUPERFAMILY SSF51735 5 242 1.46E-76 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05725 6acfe833e54375a0b087f81fd4a968b5 92 Pfam PF14165 YtzH-like protein 3 88 2.7E-36 T 15-10-2018 IPR025547 YtzH-like protein C2I28_02330 fadbec8f53bb13172c004ae4a6b2a069 93 Pfam PF04296 Protein of unknown function (DUF448) 10 82 9.6E-26 T 15-10-2018 IPR007393 Domain of unknown function DUF448 C2I28_02330 fadbec8f53bb13172c004ae4a6b2a069 93 SUPERFAMILY SSF64376 5 89 3.27E-27 T 15-10-2018 IPR035931 YlxR-like superfamily C2I28_02330 fadbec8f53bb13172c004ae4a6b2a069 93 Gene3D G3DSA:3.30.1230.10 2 93 6.9E-34 T 15-10-2018 IPR035931 YlxR-like superfamily C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 SMART SM00155 310 337 5.8E-5 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 SMART SM00155 138 165 3.7E-5 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 Pfam PF13091 PLD-like domain 56 175 1.7E-13 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 Pfam PF13091 PLD-like domain 240 363 2.8E-26 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 SUPERFAMILY SSF56024 190 381 1.1E-39 T 15-10-2018 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 SUPERFAMILY SSF56024 42 224 8.07E-41 T 15-10-2018 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 Gene3D G3DSA:3.30.870.10 36 225 2.3E-39 T 15-10-2018 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 Gene3D G3DSA:3.30.870.10 226 367 1.6E-25 T 15-10-2018 C2I28_07510 522b36a0c52c6077744e5537c21d9368 397 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 30 397 4.0E-103 T 15-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I28_10885 f591f0adc91354734723853a19526902 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 125 15.989 T 15-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I28_10885 f591f0adc91354734723853a19526902 128 TIGRFAM TIGR00494 crcB: protein CrcB 6 120 2.9E-24 T 15-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I28_10885 f591f0adc91354734723853a19526902 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 120 3.0E-21 T 15-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 500 1.0E-112 T 15-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 SUPERFAMILY SSF64518 152 501 1.06E-17 T 15-10-2018 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 Pfam PF00460 Flagella basal body rod protein 8 38 3.1E-8 T 15-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 8.4E-7 T 15-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 PRINTS PR01005 Flagellar hook-associated protein signature 134 154 8.4E-7 T 15-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 8.4E-7 T 15-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 C2I28_07135 cf72b24dc808b23d673a8e629ba5bcd2 507 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 439 500 1.1E-15 T 15-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SUPERFAMILY SSF48452 35 198 8.43E-20 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 Gene3D G3DSA:1.25.40.10 200 416 1.8E-31 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SUPERFAMILY SSF48452 204 406 1.9E-27 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 Pfam PF13176 Tetratricopeptide repeat 140 167 0.02 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 Gene3D G3DSA:1.25.40.10 27 109 2.1E-10 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 Gene3D G3DSA:1.25.40.10 110 199 1.4E-9 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 134 167 25.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 271 304 0.57 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 170 201 150.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 203 236 68.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 66 99 62.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 339 372 7.4 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 237 270 44.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 SMART SM00028 305 338 37.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_03145 a1b61f1510cca8f7759c8e956b1caacc 418 Pfam PF13429 Tetratricopeptide repeat 238 394 2.6E-6 T 15-10-2018 C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 SMART SM00930 263 338 2.4E-22 T 15-10-2018 IPR018449 NIL domain C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 SUPERFAMILY SSF55021 249 338 8.36E-20 T 15-10-2018 C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 Gene3D G3DSA:3.30.70.260 233 340 4.2E-26 T 15-10-2018 C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 Pfam PF00005 ABC transporter 21 169 1.0E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 SMART SM00382 30 226 2.3E-15 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 Pfam PF09383 NIL domain 266 337 1.8E-18 T 15-10-2018 IPR018449 NIL domain C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 SUPERFAMILY SSF52540 1 240 8.87E-83 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15955 310de93ce17500bcdbe88dbf2ad1a624 360 Gene3D G3DSA:3.40.50.300 1 232 1.0E-74 T 15-10-2018 C2I28_07390 363b47ca68c4fafcc9a8c64b7d24efd9 142 Gene3D G3DSA:3.40.50.2300 2 142 2.5E-51 T 15-10-2018 C2I28_07390 363b47ca68c4fafcc9a8c64b7d24efd9 142 SUPERFAMILY SSF52788 2 142 9.68E-37 T 15-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily C2I28_07390 363b47ca68c4fafcc9a8c64b7d24efd9 142 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 137 1.4E-30 T 15-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I28_07390 363b47ca68c4fafcc9a8c64b7d24efd9 142 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 113 128 1.1E-7 T 15-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I28_07390 363b47ca68c4fafcc9a8c64b7d24efd9 142 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.1E-7 T 15-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I28_07390 363b47ca68c4fafcc9a8c64b7d24efd9 142 SMART SM00226 2 141 4.0E-29 T 15-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I28_19980 38584ddc6ab9cc0d99b72636afb530b4 401 Pfam PF07690 Major Facilitator Superfamily 12 326 1.3E-27 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_19980 38584ddc6ab9cc0d99b72636afb530b4 401 Gene3D G3DSA:1.20.1250.20 202 388 2.6E-26 T 15-10-2018 C2I28_19980 38584ddc6ab9cc0d99b72636afb530b4 401 Gene3D G3DSA:1.20.1250.20 3 187 2.9E-20 T 15-10-2018 C2I28_19980 38584ddc6ab9cc0d99b72636afb530b4 401 SUPERFAMILY SSF103473 4 392 7.98E-50 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 Gene3D G3DSA:1.10.150.470 2 86 5.0E-28 T 15-10-2018 C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 218 242 2.7E-6 T 15-10-2018 C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 122 136 2.7E-6 T 15-10-2018 C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 Gene3D G3DSA:3.40.50.150 88 329 4.5E-51 T 15-10-2018 C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 PIRSF PIRSF026567 2 330 8.5E-139 T 15-10-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 Pfam PF02384 N-6 DNA Methylase 98 310 2.5E-14 T 15-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 C2I28_05520 e3be279f44c184ca6fa44a67904fea44 330 SUPERFAMILY SSF53335 10 311 4.76E-45 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Pfam PF13492 GAF domain 261 364 1.1E-6 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 SMART SM00065 238 373 1.1E-11 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 SMART SM00387 468 578 7.4E-6 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Pfam PF07694 5TMR of 5TMR-LYT 26 207 6.0E-60 T 15-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Gene3D G3DSA:1.10.1760.20 73 219 2.7E-7 T 15-10-2018 C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Pfam PF06580 Histidine kinase 378 456 1.4E-24 T 15-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 SUPERFAMILY SSF55781 241 364 2.02E-7 T 15-10-2018 C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Gene3D G3DSA:3.30.450.40 241 364 2.4E-5 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 SUPERFAMILY SSF55874 441 576 3.14E-15 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 476 576 1.6E-9 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12070 819505ec75c049ee901e75d0cc98d83e 583 Gene3D G3DSA:3.30.565.10 436 581 6.6E-16 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_22395 3c41dd83a57752f51996e05b16346a78 274 ProSitePatterns PS01123 Thermonuclease family signature 1. 75 100 - T 15-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 C2I28_22395 3c41dd83a57752f51996e05b16346a78 274 Gene3D G3DSA:2.40.50.90 58 203 8.7E-53 T 15-10-2018 IPR035437 SNase-like, OB-fold superfamily C2I28_22395 3c41dd83a57752f51996e05b16346a78 274 Pfam PF00565 Staphylococcal nuclease homologue 90 195 2.9E-29 T 15-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 C2I28_22395 3c41dd83a57752f51996e05b16346a78 274 SUPERFAMILY SSF50199 68 199 9.94E-38 T 15-10-2018 C2I28_22395 3c41dd83a57752f51996e05b16346a78 274 SMART SM00318 64 196 1.6E-40 T 15-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 SMART SM00228 109 185 2.2E-6 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 3 415 1.3E-176 T 15-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 Gene3D G3DSA:2.30.42.10 133 211 4.4E-15 T 15-10-2018 C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 SUPERFAMILY SSF50494 343 409 8.05E-7 T 15-10-2018 IPR009003 Peptidase S1, PA clan C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 Pfam PF05580 SpoIVB peptidase S55 202 410 1.2E-87 T 15-10-2018 IPR008763 Peptidase S55, SpoIVB C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 SUPERFAMILY SSF50156 114 194 2.5E-11 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_03815 32f06cb3f1655e4be0899637791f7570 426 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 107 181 2.4E-7 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_12635 264be66b3af94ceadad36dab9283e0a4 209 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 2.7E-27 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_12635 264be66b3af94ceadad36dab9283e0a4 209 SMART SM00934 2 203 4.0E-37 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_12635 264be66b3af94ceadad36dab9283e0a4 209 SUPERFAMILY SSF51366 3 208 8.87E-40 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_12635 264be66b3af94ceadad36dab9283e0a4 209 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 207 1.7E-84 T 15-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 C2I28_12635 264be66b3af94ceadad36dab9283e0a4 209 Gene3D G3DSA:3.20.20.70 1 209 1.1E-73 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_13575 91cb3a014659009836393fffa30e5645 772 SUPERFAMILY SSF89260 36 127 3.01E-8 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 SUPERFAMILY SSF89260 384 487 7.06E-9 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 SUPERFAMILY SSF89260 264 373 4.18E-9 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 SUPERFAMILY SSF89260 145 257 3.27E-11 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 Gene3D G3DSA:2.60.120.380 30 137 4.5E-18 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 Gene3D G3DSA:2.60.120.380 378 496 2.0E-17 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 Gene3D G3DSA:2.60.120.380 138 258 8.1E-22 T 15-10-2018 C2I28_13575 91cb3a014659009836393fffa30e5645 772 Gene3D G3DSA:2.60.120.380 259 377 9.5E-20 T 15-10-2018 C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 Pfam PF00298 Ribosomal protein L11, RNA binding domain 85 153 1.6E-26 T 15-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 SUPERFAMILY SSF46906 81 154 1.19E-27 T 15-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 Pfam PF03946 Ribosomal protein L11, N-terminal domain 23 80 3.1E-31 T 15-10-2018 IPR020784 Ribosomal protein L11, N-terminal C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 SUPERFAMILY SSF54747 15 98 1.09E-30 T 15-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 SMART SM00649 23 154 7.9E-89 T 15-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 Gene3D G3DSA:1.10.10.250 86 154 5.5E-30 T 15-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 19 155 31.92 T 15-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 ProSitePatterns PS00359 Ribosomal protein L11 signature. 140 155 - T 15-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 Gene3D G3DSA:3.30.1550.10 16 85 4.9E-34 T 15-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 17 155 4.9E-65 T 15-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08620 93cc4ad2fafdbff283b8c804f2db5195 155 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 50 87 5.0E-16 T 15-10-2018 C2I28_24200 05f5fcf820469ea46cb54846d89d3078 459 Pfam PF03929 PepSY-associated TM region 27 398 1.3E-65 T 15-10-2018 IPR005625 PepSY-associated TM protein C2I28_24200 05f5fcf820469ea46cb54846d89d3078 459 Pfam PF03413 Peptidase propeptide and YPEB domain 286 345 2.5E-5 T 15-10-2018 IPR025711 PepSY domain C2I28_09695 ef34854122300e9af97c36725bb8ffd5 310 SUPERFAMILY SSF52540 3 221 3.16E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09695 ef34854122300e9af97c36725bb8ffd5 310 Pfam PF00005 ABC transporter 20 159 1.1E-26 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09695 ef34854122300e9af97c36725bb8ffd5 310 SMART SM00382 28 215 1.4E-6 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09695 ef34854122300e9af97c36725bb8ffd5 310 Gene3D G3DSA:3.40.50.300 1 233 6.1E-60 T 15-10-2018 C2I28_09695 ef34854122300e9af97c36725bb8ffd5 310 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_09695 ef34854122300e9af97c36725bb8ffd5 310 Pfam PF13732 Domain of unknown function (DUF4162) 212 301 6.5E-9 T 15-10-2018 IPR025302 Domain of unknown function DUF4162 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 557 47.015 T 15-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 Pfam PF00920 Dehydratase family 34 553 2.8E-225 T 15-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 15-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 SUPERFAMILY SSF52016 377 556 3.14E-62 T 15-10-2018 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 SUPERFAMILY SSF143975 4 376 4.18E-139 T 15-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 Gene3D G3DSA:3.50.30.80 377 528 1.2E-53 T 15-10-2018 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 15-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_20655 6aa3fba5e7a22f8494bc186f70ea6e24 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 557 2.3E-262 T 15-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 Gene3D G3DSA:3.40.50.720 29 204 5.1E-59 T 15-10-2018 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 SUPERFAMILY SSF51735 29 212 3.74E-60 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 172 185 4.9E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 248 265 4.9E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 196 224 4.9E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 357 383 4.9E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 266 282 4.9E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 Gene3D G3DSA:3.30.360.10 205 514 1.1E-111 T 15-10-2018 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 32 513 77.545 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 SUPERFAMILY SSF55347 211 512 8.5E-101 T 15-10-2018 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 33 512 2.8E-170 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 PIRSF PIRSF000110 16 515 7.6E-180 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 36 216 6.3E-61 T 15-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_17610 6634e1f97ccd47359af467406ffed94c 528 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 219 511 6.2E-101 T 15-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 202 1.6E-80 T 15-10-2018 IPR015796 Impact family, bacterial/archaeal C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 15-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 9.3E-18 T 15-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 SUPERFAMILY SSF54980 135 199 7.19E-10 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 SUPERFAMILY SSF54211 3 131 2.35E-46 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 Gene3D G3DSA:3.30.230.30 1 133 3.1E-54 T 15-10-2018 IPR036956 Impact, N-terminal domain superfamily C2I28_07190 f7fc7b54046bbd6bd929fb003579eb09 211 Pfam PF01205 Uncharacterized protein family UPF0029 19 124 3.1E-34 T 15-10-2018 IPR001498 Impact, N-terminal C2I28_26240 6f02d3bc44957ef5c240a2d0965ab4af 68 Gene3D G3DSA:1.10.260.40 1 67 4.5E-19 T 15-10-2018 C2I28_26240 6f02d3bc44957ef5c240a2d0965ab4af 68 SUPERFAMILY SSF47413 3 63 4.61E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_26240 6f02d3bc44957ef5c240a2d0965ab4af 68 Pfam PF01381 Helix-turn-helix 4 58 1.3E-19 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26240 6f02d3bc44957ef5c240a2d0965ab4af 68 SMART SM00530 3 59 8.8E-18 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26340 6f02d3bc44957ef5c240a2d0965ab4af 68 Gene3D G3DSA:1.10.260.40 1 67 4.5E-19 T 15-10-2018 C2I28_26340 6f02d3bc44957ef5c240a2d0965ab4af 68 SUPERFAMILY SSF47413 3 63 4.61E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_26340 6f02d3bc44957ef5c240a2d0965ab4af 68 Pfam PF01381 Helix-turn-helix 4 58 1.3E-19 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26340 6f02d3bc44957ef5c240a2d0965ab4af 68 SMART SM00530 3 59 8.8E-18 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27190 6f02d3bc44957ef5c240a2d0965ab4af 68 Gene3D G3DSA:1.10.260.40 1 67 4.5E-19 T 15-10-2018 C2I28_27190 6f02d3bc44957ef5c240a2d0965ab4af 68 SUPERFAMILY SSF47413 3 63 4.61E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_27190 6f02d3bc44957ef5c240a2d0965ab4af 68 Pfam PF01381 Helix-turn-helix 4 58 1.3E-19 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27190 6f02d3bc44957ef5c240a2d0965ab4af 68 SMART SM00530 3 59 8.8E-18 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27090 6f02d3bc44957ef5c240a2d0965ab4af 68 Gene3D G3DSA:1.10.260.40 1 67 4.5E-19 T 15-10-2018 C2I28_27090 6f02d3bc44957ef5c240a2d0965ab4af 68 SUPERFAMILY SSF47413 3 63 4.61E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_27090 6f02d3bc44957ef5c240a2d0965ab4af 68 Pfam PF01381 Helix-turn-helix 4 58 1.3E-19 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27090 6f02d3bc44957ef5c240a2d0965ab4af 68 SMART SM00530 3 59 8.8E-18 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_16530 c2577723feddd2382b1b75f0058d0f28 103 SUPERFAMILY SSF103481 5 101 6.93E-12 T 15-10-2018 C2I28_16530 c2577723feddd2382b1b75f0058d0f28 103 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.9E-17 T 15-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I28_16530 c2577723feddd2382b1b75f0058d0f28 103 Gene3D G3DSA:1.10.3730.20 1 103 1.8E-23 T 15-10-2018 C2I28_03455 ed58f0163d14a6c6ad9914a63e57da70 39 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 13 35 1.2E-13 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_03455 ed58f0163d14a6c6ad9914a63e57da70 39 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 14 36 8.1E-14 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_21615 a04ee34e947294d1db5d4aaea7952ad6 326 Pfam PF12679 ABC-2 family transporter protein 4 325 5.5E-24 T 15-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 PIRSF PIRSF000386 1 246 5.9E-107 T 15-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 113.253 T 15-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 SUPERFAMILY SSF75217 1 243 1.31E-102 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 3.6E-75 T 15-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 Gene3D G3DSA:1.10.1270.20 165 246 8.8E-36 T 15-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 Gene3D G3DSA:3.40.1280.10 1 164 2.9E-69 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_02615 9093ee3dd0e2a442b5b4edc13d7731f8 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 4.7E-105 T 15-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 SUPERFAMILY SSF50249 1 64 4.29E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 PRINTS PR00050 Cold shock protein signature 24 33 6.7E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 PRINTS PR00050 Cold shock protein signature 39 57 6.7E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 PRINTS PR00050 Cold shock protein signature 4 19 6.7E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 SMART SM00357 3 66 2.1E-32 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 Gene3D G3DSA:2.40.50.140 1 66 4.4E-31 T 15-10-2018 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.5E-31 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21635 a4f1618bcc2c48241b65ca00ce5f2cb1 66 PIRSF PIRSF002599 1 66 2.8E-25 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_25010 80db12aa86ba57ad99d5728b65e1a1b7 420 Pfam PF00916 Sulfate permease family 14 378 6.1E-75 T 15-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 SMART SM00257 30 75 3.1E-18 T 15-10-2018 IPR018392 LysM domain C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 SUPERFAMILY SSF54106 29 75 5.1E-13 T 15-10-2018 C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 Pfam PF01476 LysM domain 31 75 3.7E-17 T 15-10-2018 IPR018392 LysM domain C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 82 205 7.2E-65 T 15-10-2018 IPR014258 CAP domain, YkwD-like C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 Gene3D G3DSA:3.40.33.10 80 207 5.5E-49 T 15-10-2018 IPR035940 CAP superfamily C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 Gene3D G3DSA:3.10.350.10 26 79 5.1E-17 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 Pfam PF00188 Cysteine-rich secretory protein family 89 204 9.5E-22 T 15-10-2018 IPR014044 CAP domain C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 33 76 2.2E-24 T 15-10-2018 IPR014248 Spore coat assembly protein SafA C2I28_01510 74f99f9db32804b676a1b6e799ecace1 207 SUPERFAMILY SSF55797 81 204 3.79E-29 T 15-10-2018 IPR035940 CAP superfamily C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 401 1.5E-119 T 15-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 SUPERFAMILY SSF55021 249 324 1.04E-12 T 15-10-2018 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 Gene3D G3DSA:3.30.70.260 260 337 5.9E-48 T 15-10-2018 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 Gene3D G3DSA:3.40.1160.10 1 253 4.6E-90 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 15-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 SUPERFAMILY SSF55021 328 405 1.76E-21 T 15-10-2018 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 Pfam PF13840 ACT domain 335 397 8.6E-16 T 15-10-2018 IPR027795 CASTOR, ACT domain C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 Pfam PF00696 Amino acid kinase family 3 229 3.6E-54 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 PIRSF PIRSF000726 1 60 1.1E-22 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 PIRSF PIRSF000726 54 409 1.1E-132 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.3E-148 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 Gene3D G3DSA:3.30.70.260 254 402 5.9E-48 T 15-10-2018 C2I28_05185 16d3eda383f34b297a1e7b32b8b2789f 410 SUPERFAMILY SSF53633 3 242 1.96E-72 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00941 Cadmium-transporting ATPase signature 47 64 1.4E-16 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00941 Cadmium-transporting ATPase signature 64 76 1.4E-16 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00941 Cadmium-transporting ATPase signature 139 155 1.4E-16 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00941 Cadmium-transporting ATPase signature 200 216 1.4E-16 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00941 Cadmium-transporting ATPase signature 119 139 1.4E-16 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00941 Cadmium-transporting ATPase signature 219 233 1.4E-16 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 Gene3D G3DSA:3.40.1110.10 346 466 2.6E-85 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 15-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 SUPERFAMILY SSF56784 334 633 7.84E-56 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 Gene3D G3DSA:3.40.50.1000 316 585 2.6E-85 T 15-10-2018 IPR023214 HAD superfamily C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 107 614 2.9E-86 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 3.2E-30 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 184 198 3.2E-30 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 3.2E-30 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 3.2E-30 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 470 3.2E-30 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 3.2E-30 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 Pfam PF00122 E1-E2 ATPase 135 315 2.7E-48 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 84 636 6.4E-181 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 Pfam PF00702 haloacid dehalogenase-like hydrolase 333 548 6.5E-38 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 SUPERFAMILY SSF81653 137 234 3.01E-26 T 15-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 SUPERFAMILY SSF81665 86 613 4.97E-19 T 15-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 84 421 2.9E-96 T 15-10-2018 C2I28_09945 dfc07176f20187a7a9d222a0a4254a74 639 Gene3D G3DSA:2.70.150.20 122 238 4.9E-36 T 15-10-2018 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 Gene3D G3DSA:2.40.180.10 28 527 2.6E-224 T 15-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 SUPERFAMILY SSF56634 20 512 2.49E-202 T 15-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 Pfam PF06628 Catalase-related immune-responsive 447 508 2.3E-18 T 15-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 SMART SM01060 32 425 4.9E-260 T 15-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 ProSitePatterns PS00438 Catalase proximal active site signature. 68 84 - T 15-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PIRSF PIRSF038928 22 514 2.6E-181 T 15-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 Pfam PF00199 Catalase 32 421 1.4E-176 T 15-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 363 371 - T 15-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PRINTS PR00067 Catalase signature 45 68 2.3E-69 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PRINTS PR00067 Catalase signature 318 345 2.3E-69 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PRINTS PR00067 Catalase signature 113 131 2.3E-69 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PRINTS PR00067 Catalase signature 350 376 2.3E-69 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PRINTS PR00067 Catalase signature 134 151 2.3E-69 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_23190 08b5bcf5f8c0c721a5165cfcea37da10 564 PRINTS PR00067 Catalase signature 153 171 2.3E-69 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_00990 0bbf6c6efde2caceca6fe01e7eef08fe 473 SUPERFAMILY SSF53448 250 404 1.0E-22 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_00990 0bbf6c6efde2caceca6fe01e7eef08fe 473 Pfam PF00535 Glycosyl transferase family 2 5 126 4.1E-20 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_00990 0bbf6c6efde2caceca6fe01e7eef08fe 473 Pfam PF00535 Glycosyl transferase family 2 252 355 9.4E-18 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_00990 0bbf6c6efde2caceca6fe01e7eef08fe 473 SUPERFAMILY SSF53448 1 114 2.94E-23 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_00990 0bbf6c6efde2caceca6fe01e7eef08fe 473 Gene3D G3DSA:3.90.550.10 239 461 2.9E-25 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_00990 0bbf6c6efde2caceca6fe01e7eef08fe 473 Gene3D G3DSA:3.90.550.10 1 212 8.8E-27 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_02910 d609aeb35f83014db267158efcca8b19 273 Gene3D G3DSA:3.60.140.10 6 273 1.0E-91 T 15-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily C2I28_02910 d609aeb35f83014db267158efcca8b19 273 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 32 268 1.7E-71 T 15-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase C2I28_02910 d609aeb35f83014db267158efcca8b19 273 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 37 270 2.2E-58 T 15-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase C2I28_02910 d609aeb35f83014db267158efcca8b19 273 SUPERFAMILY SSF64438 14 272 6.96E-80 T 15-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic C2I28_08355 1c544ae00e6f81127bba119339905270 459 SUPERFAMILY SSF53448 4 307 4.51E-68 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_08355 1c544ae00e6f81127bba119339905270 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 42.069 T 15-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 C2I28_08355 1c544ae00e6f81127bba119339905270 459 SUPERFAMILY SSF51161 254 447 2.46E-49 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_08355 1c544ae00e6f81127bba119339905270 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 8.3E-189 T 15-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 C2I28_08355 1c544ae00e6f81127bba119339905270 459 Gene3D G3DSA:3.90.550.10 1 252 4.4E-81 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_08355 1c544ae00e6f81127bba119339905270 459 Gene3D G3DSA:2.160.10.10 253 439 5.6E-52 T 15-10-2018 C2I28_08355 1c544ae00e6f81127bba119339905270 459 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 15-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I28_08355 1c544ae00e6f81127bba119339905270 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 1.1E-8 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_08355 1c544ae00e6f81127bba119339905270 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 1.0E-6 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_08355 1c544ae00e6f81127bba119339905270 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 6.1E-7 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_08355 1c544ae00e6f81127bba119339905270 459 Pfam PF00483 Nucleotidyl transferase 6 212 4.9E-25 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_09295 7803e80527fb971e5c9f3663f2c5e2bf 232 Gene3D G3DSA:3.30.420.40 3 217 1.9E-52 T 15-10-2018 C2I28_09295 7803e80527fb971e5c9f3663f2c5e2bf 232 Pfam PF00814 Glycoprotease family 30 133 1.0E-32 T 15-10-2018 IPR000905 Gcp-like domain C2I28_09295 7803e80527fb971e5c9f3663f2c5e2bf 232 SUPERFAMILY SSF53067 108 215 7.12E-15 T 15-10-2018 C2I28_09295 7803e80527fb971e5c9f3663f2c5e2bf 232 SUPERFAMILY SSF53067 1 103 2.85E-29 T 15-10-2018 C2I28_09295 7803e80527fb971e5c9f3663f2c5e2bf 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 217 2.3E-54 T 15-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 C2I28_09295 7803e80527fb971e5c9f3663f2c5e2bf 232 Gene3D G3DSA:3.30.420.40 95 190 1.9E-52 T 15-10-2018 C2I28_13635 880429cb5ca42c6849ece9e622112060 523 Gene3D G3DSA:2.160.20.10 62 368 1.2E-23 T 15-10-2018 IPR012334 Pectin lyase fold C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 384 406 560.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 223 245 240.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 457 485 6500.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 407 433 6800.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 312 346 3700.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 279 301 3.9 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 257 278 33.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 355 383 3000.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 199 221 0.36 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 130 153 9400.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SMART SM00710 434 456 3500.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_13635 880429cb5ca42c6849ece9e622112060 523 Pfam PF13229 Right handed beta helix region 124 278 2.6E-12 T 15-10-2018 IPR039448 Right handed beta helix domain C2I28_13635 880429cb5ca42c6849ece9e622112060 523 Pfam PF13229 Right handed beta helix region 354 503 1.3E-11 T 15-10-2018 IPR039448 Right handed beta helix domain C2I28_13635 880429cb5ca42c6849ece9e622112060 523 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 193 236 1.1E-4 T 15-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SUPERFAMILY SSF51126 354 500 2.55E-11 T 15-10-2018 IPR011050 Pectin lyase fold/virulence factor C2I28_13635 880429cb5ca42c6849ece9e622112060 523 SUPERFAMILY SSF51126 57 363 8.71E-27 T 15-10-2018 IPR011050 Pectin lyase fold/virulence factor C2I28_13635 880429cb5ca42c6849ece9e622112060 523 Gene3D G3DSA:2.160.20.10 369 521 9.1E-6 T 15-10-2018 IPR012334 Pectin lyase fold C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 ProSitePatterns PS00501 Signal peptidases I serine active site. 35 42 - T 15-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 ProSitePatterns PS00761 Signal peptidases I signature 3. 140 153 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 177 4.5E-51 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 135 154 4.6E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 26 42 4.6E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 4.6E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 Pfam PF00717 Peptidase S24-like 33 101 9.3E-19 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 SUPERFAMILY SSF51306 24 183 1.26E-50 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 Gene3D G3DSA:2.10.109.10 58 183 2.5E-46 T 15-10-2018 C2I28_26135 39af4b1c6761892fd6317b501dfec4cf 184 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_21455 c99419d6e9e4d70007debd3032594dde 239 Pfam PF04493 Endonuclease V 23 223 1.0E-57 T 15-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 C2I28_21455 c99419d6e9e4d70007debd3032594dde 239 Gene3D G3DSA:3.30.2170.10 2 239 3.9E-75 T 15-10-2018 C2I28_21455 c99419d6e9e4d70007debd3032594dde 239 Hamap MF_00801 Endonuclease V [nfi]. 13 233 30.104 T 15-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 SMART SM00448 1 112 2.9E-20 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 SUPERFAMILY SSF52172 2 124 3.84E-27 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 Gene3D G3DSA:2.40.50.40 129 194 6.9E-14 T 15-10-2018 C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 Pfam PF00072 Response regulator receiver domain 5 112 6.9E-21 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 Pfam PF04397 LytTr DNA-binding domain 137 224 1.1E-17 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 SMART SM00850 134 232 4.3E-19 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_14120 bae59575f9dafd9da5fdbaa8802a0031 232 Gene3D G3DSA:3.40.50.2300 1 128 3.5E-28 T 15-10-2018 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.8E-18 T 15-10-2018 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.8E-18 T 15-10-2018 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.8E-18 T 15-10-2018 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.8E-18 T 15-10-2018 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.8E-18 T 15-10-2018 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 Gene3D G3DSA:3.40.640.10 62 284 1.2E-141 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 15-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 SUPERFAMILY SSF53383 3 391 2.02E-116 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 Pfam PF00155 Aminotransferase class I and II 31 385 3.0E-79 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_15030 ba37feb5415a5dafe272074ed36766fc 394 Gene3D G3DSA:3.90.1150.10 25 385 1.2E-141 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_22805 3b2b795c384c5d21a8b64805ff2ad180 167 SUPERFAMILY SSF49764 79 163 3.03E-7 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_22805 3b2b795c384c5d21a8b64805ff2ad180 167 Gene3D G3DSA:2.60.40.790 71 154 1.2E-7 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_21250 3530f122989027d00b683d63a40a63d5 65 Gene3D G3DSA:4.10.810.10 12 65 6.7E-15 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_21250 3530f122989027d00b683d63a40a63d5 65 Pfam PF08858 IDEAL domain 25 61 1.1E-12 T 15-10-2018 IPR014957 IDEAL domain C2I28_21250 3530f122989027d00b683d63a40a63d5 65 SMART SM00914 25 61 1.4E-8 T 15-10-2018 IPR014957 IDEAL domain C2I28_05285 6649ba1182fa348800488680cd48715e 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 8.4E-117 T 15-10-2018 IPR008007 Peptidase M42 C2I28_05285 6649ba1182fa348800488680cd48715e 361 PIRSF PIRSF001123 4 361 3.0E-148 T 15-10-2018 IPR008007 Peptidase M42 C2I28_05285 6649ba1182fa348800488680cd48715e 361 SUPERFAMILY SSF101821 73 182 6.26E-34 T 15-10-2018 C2I28_05285 6649ba1182fa348800488680cd48715e 361 Gene3D G3DSA:2.40.30.40 77 164 1.1E-135 T 15-10-2018 IPR023367 Peptidase M42, domain 2 C2I28_05285 6649ba1182fa348800488680cd48715e 361 SUPERFAMILY SSF53187 6 358 6.29E-72 T 15-10-2018 C2I28_05285 6649ba1182fa348800488680cd48715e 361 Gene3D G3DSA:3.40.630.10 12 345 1.1E-135 T 15-10-2018 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Gene3D G3DSA:2.170.220.10 119 238 2.7E-154 T 15-10-2018 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 SUPERFAMILY SSF52374 4 364 1.77E-117 T 15-10-2018 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 532 660 2.2E-47 T 15-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Gene3D G3DSA:3.40.50.620 8 344 2.7E-154 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Pfam PF09334 tRNA synthetases class I (M) 8 373 1.8E-121 T 15-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Pfam PF08264 Anticodon-binding domain of tRNA 403 536 5.7E-10 T 15-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 SUPERFAMILY SSF47323 363 573 6.38E-48 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Gene3D G3DSA:2.40.50.140 550 660 4.1E-37 T 15-10-2018 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 361 372 5.1E-34 T 15-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 5.1E-34 T 15-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 236 247 5.1E-34 T 15-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 5.1E-34 T 15-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 269 284 5.1E-34 T 15-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 5.1E-34 T 15-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 SUPERFAMILY SSF50249 559 659 4.16E-33 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Gene3D G3DSA:1.10.730.10 351 521 1.5E-53 T 15-10-2018 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 522 51.625 T 15-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 Pfam PF01588 Putative tRNA binding domain 566 658 1.5E-27 T 15-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I28_08300 137d452daf6c066ecdfa6a330e64e3f0 660 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 524 7.0E-182 T 15-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 SUPERFAMILY SSF53067 147 331 5.25E-50 T 15-10-2018 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 333 5.6E-161 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 Pfam PF06723 MreB/Mbl protein 7 332 6.4E-152 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 8.6E-62 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 8.6E-62 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 8.6E-62 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 8.6E-62 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 8.6E-62 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 Gene3D G3DSA:3.30.420.40 151 314 1.1E-131 T 15-10-2018 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 SUPERFAMILY SSF53067 8 144 1.55E-38 T 15-10-2018 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 Gene3D G3DSA:3.30.420.40 9 324 1.1E-131 T 15-10-2018 C2I28_04895 f4ce800dbafdeabd08c7d4c94a506bfa 341 Gene3D G3DSA:3.90.640.10 183 256 1.1E-131 T 15-10-2018 C2I28_21135 a1ee12463d09ece424ab74da1ad8857e 179 SUPERFAMILY SSF160631 29 163 3.4E-17 T 15-10-2018 C2I28_21135 a1ee12463d09ece424ab74da1ad8857e 179 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 39 112 1.7E-10 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_21135 a1ee12463d09ece424ab74da1ad8857e 179 SMART SM00860 39 150 4.0E-6 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_21135 a1ee12463d09ece424ab74da1ad8857e 179 Gene3D G3DSA:3.40.1580.10 27 160 5.5E-17 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_01705 b06999d733a1ac62dfda046b28b979c2 208 SUPERFAMILY SSF48317 8 203 7.33E-39 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_01705 b06999d733a1ac62dfda046b28b979c2 208 Gene3D G3DSA:1.20.144.10 4 116 3.0E-10 T 15-10-2018 C2I28_01705 b06999d733a1ac62dfda046b28b979c2 208 Gene3D G3DSA:1.20.144.10 117 208 6.1E-24 T 15-10-2018 C2I28_01705 b06999d733a1ac62dfda046b28b979c2 208 SMART SM00014 86 198 1.5E-20 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_01705 b06999d733a1ac62dfda046b28b979c2 208 Pfam PF01569 PAP2 superfamily 96 202 4.1E-18 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_01460 e1480a42f588100a9f76025d9453d837 461 SUPERFAMILY SSF51905 2 456 1.81E-40 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01460 e1480a42f588100a9f76025d9453d837 461 SUPERFAMILY SSF54373 300 406 2.35E-17 T 15-10-2018 C2I28_01460 e1480a42f588100a9f76025d9453d837 461 Gene3D G3DSA:1.10.3110.10 106 199 4.2E-115 T 15-10-2018 C2I28_01460 e1480a42f588100a9f76025d9453d837 461 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 458 3.1E-76 T 15-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 C2I28_01460 e1480a42f588100a9f76025d9453d837 461 Gene3D G3DSA:3.90.660.20 40 406 4.2E-115 T 15-10-2018 C2I28_01460 e1480a42f588100a9f76025d9453d837 461 Gene3D G3DSA:3.50.50.60 5 448 4.2E-115 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01460 e1480a42f588100a9f76025d9453d837 461 Pfam PF01593 Flavin containing amine oxidoreductase 11 456 3.3E-44 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 10 491 5.3E-164 T 15-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 Gene3D G3DSA:3.40.50.300 5 247 3.8E-55 T 15-10-2018 C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 SUPERFAMILY SSF52317 197 436 1.8E-32 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 499 163.324 T 15-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 260 444 4.9E-55 T 15-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 Gene3D G3DSA:3.40.50.880 258 444 1.0E-19 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 SUPERFAMILY SSF52540 10 244 2.28E-51 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_22830 0653fe5856bd8c3a74c55849b0369b59 508 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 10 242 1.1E-20 T 15-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain C2I28_10900 3c55949c1c70eb36aa1e97ff138c41ae 375 Gene3D G3DSA:3.30.9.10 92 311 7.0E-110 T 15-10-2018 C2I28_10900 3c55949c1c70eb36aa1e97ff138c41ae 375 Gene3D G3DSA:3.50.50.60 6 352 7.0E-110 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_10900 3c55949c1c70eb36aa1e97ff138c41ae 375 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 355 3.2E-102 T 15-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 C2I28_10900 3c55949c1c70eb36aa1e97ff138c41ae 375 Pfam PF01266 FAD dependent oxidoreductase 6 350 5.1E-72 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_10900 3c55949c1c70eb36aa1e97ff138c41ae 375 SUPERFAMILY SSF51905 4 369 1.42E-50 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_10900 3c55949c1c70eb36aa1e97ff138c41ae 375 SUPERFAMILY SSF54373 224 311 3.66E-17 T 15-10-2018 C2I28_19070 697a1d0d0b78171c303509b95b4ed4b0 405 SUPERFAMILY SSF103473 12 394 1.83E-56 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_19070 697a1d0d0b78171c303509b95b4ed4b0 405 Gene3D G3DSA:1.20.1250.20 13 199 4.6E-21 T 15-10-2018 C2I28_19070 697a1d0d0b78171c303509b95b4ed4b0 405 Gene3D G3DSA:1.20.1250.20 216 400 2.0E-23 T 15-10-2018 C2I28_19070 697a1d0d0b78171c303509b95b4ed4b0 405 Pfam PF07690 Major Facilitator Superfamily 23 359 1.1E-29 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_05705 229a75daaa561f82b3d4ab774bd78447 357 SUPERFAMILY SSF101821 71 180 1.05E-31 T 15-10-2018 C2I28_05705 229a75daaa561f82b3d4ab774bd78447 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 2.0E-110 T 15-10-2018 IPR008007 Peptidase M42 C2I28_05705 229a75daaa561f82b3d4ab774bd78447 357 Gene3D G3DSA:3.40.630.10 10 340 3.9E-118 T 15-10-2018 C2I28_05705 229a75daaa561f82b3d4ab774bd78447 357 SUPERFAMILY SSF53187 4 351 3.52E-68 T 15-10-2018 C2I28_05705 229a75daaa561f82b3d4ab774bd78447 357 PIRSF PIRSF001123 2 356 2.6E-149 T 15-10-2018 IPR008007 Peptidase M42 C2I28_05705 229a75daaa561f82b3d4ab774bd78447 357 Gene3D G3DSA:2.40.30.40 75 162 3.9E-118 T 15-10-2018 IPR023367 Peptidase M42, domain 2 C2I28_19610 8de9bb82bc6971b247198aaa96cfcd2d 325 Gene3D G3DSA:3.10.180.10 5 309 5.1E-111 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_19610 8de9bb82bc6971b247198aaa96cfcd2d 325 SUPERFAMILY SSF54593 3 302 1.3E-47 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_19610 8de9bb82bc6971b247198aaa96cfcd2d 325 Gene3D G3DSA:3.10.180.10 66 217 5.1E-111 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_19610 8de9bb82bc6971b247198aaa96cfcd2d 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 161 264 2.9E-7 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_19610 8de9bb82bc6971b247198aaa96cfcd2d 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 111 1.1E-11 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 SUPERFAMILY SSF55961 178 378 3.22E-37 T 15-10-2018 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 SUPERFAMILY SSF50022 17 155 5.5E-44 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 184 377 1.4E-40 T 15-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 Gene3D G3DSA:2.102.10.10 38 161 2.6E-39 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 Gene3D G3DSA:3.90.380.10 162 240 3.7E-20 T 15-10-2018 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 Gene3D G3DSA:3.90.380.10 241 381 3.3E-32 T 15-10-2018 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 55 70 8.6E-24 T 15-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 76 96 8.6E-24 T 15-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 97 117 8.6E-24 T 15-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 184 206 8.6E-24 T 15-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 25 50 8.6E-24 T 15-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 140 166 8.6E-24 T 15-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 C2I28_15705 f7019d6c00e2f31c7fd19e8ea021dd1c 382 Pfam PF00355 Rieske [2Fe-2S] domain 40 124 6.9E-17 T 15-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 SUPERFAMILY SSF56024 289 485 4.26E-44 T 15-10-2018 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 SUPERFAMILY SSF56024 118 331 8.07E-51 T 15-10-2018 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 38 500 5.6E-145 T 15-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 Pfam PF13091 PLD-like domain 154 297 3.5E-13 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 Pfam PF13091 PLD-like domain 342 467 3.6E-25 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 SMART SM00155 413 440 7.6E-7 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 SMART SM00155 237 264 8.1E-6 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 Pfam PF13396 Phospholipase_D-nuclease N-terminal 41 81 5.6E-8 T 15-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 Gene3D G3DSA:3.30.870.10 321 471 4.3E-27 T 15-10-2018 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 Gene3D G3DSA:3.30.870.10 130 320 3.9E-42 T 15-10-2018 C2I28_15525 ace11290b994a10fc27bf454d5cb321c 500 Hamap MF_01916 Cardiolipin synthase. 34 500 39.074 T 15-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 C2I28_09890 fb168a7c0d4cc423a6b3ccbe6f69820f 43 ProDom PD049467 YFLJ 1 42 8.0E-11 T 15-10-2018 IPR022580 Protein of unknown function DUF2639 C2I28_09890 fb168a7c0d4cc423a6b3ccbe6f69820f 43 Pfam PF11121 Protein of unknown function (DUF2639) 2 38 5.6E-23 T 15-10-2018 IPR022580 Protein of unknown function DUF2639 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 174 5.7E-54 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 8.8E-89 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 67 96 8.8E-89 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 358 380 8.8E-89 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 8.8E-89 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 250 277 8.8E-89 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 120 145 8.8E-89 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 PIRSF PIRSF000109 1 470 8.8E-249 T 15-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 468 2.1E-139 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 Gene3D G3DSA:3.40.50.720 1 180 5.6E-60 T 15-10-2018 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 254 266 - T 15-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 SUPERFAMILY SSF48179 177 469 6.05E-135 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 Gene3D G3DSA:1.10.1040.10 181 436 3.9E-114 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 SMART SM01350 179 469 6.8E-235 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 SUPERFAMILY SSF51735 4 177 2.18E-57 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_07630 23a78acbbceb24e175e0330870543db9 470 Gene3D G3DSA:1.20.5.320 437 470 1.7E-21 T 15-10-2018 C2I28_07630 23a78acbbceb24e175e0330870543db9 470 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 469 3.3E-235 T 15-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_23355 555c345788623c565e025b7c62907520 345 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 8 343 35.697 T 15-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 C2I28_23355 555c345788623c565e025b7c62907520 345 Gene3D G3DSA:3.40.50.10210 52 324 4.3E-131 T 15-10-2018 C2I28_23355 555c345788623c565e025b7c62907520 345 Pfam PF02277 Phosphoribosyltransferase 6 341 1.2E-132 T 15-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 C2I28_23355 555c345788623c565e025b7c62907520 345 SUPERFAMILY SSF52733 4 342 7.06E-118 T 15-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 C2I28_23355 555c345788623c565e025b7c62907520 345 Gene3D G3DSA:1.10.1610.10 20 341 4.3E-131 T 15-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 C2I28_23355 555c345788623c565e025b7c62907520 345 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 11 341 1.6E-133 T 15-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SMART SM00388 362 429 7.8E-24 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Pfam PF00512 His Kinase A (phospho-acceptor) domain 363 428 4.6E-20 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Pfam PF16736 Single Cache-like 33 151 1.8E-24 T 15-10-2018 IPR031967 PhoR, single Cache-like domain C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Gene3D G3DSA:3.30.450.20 37 159 3.6E-7 T 15-10-2018 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 584 2.5E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Gene3D G3DSA:3.30.565.10 435 586 4.2E-50 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SUPERFAMILY SSF55874 418 583 6.81E-50 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SMART SM00387 475 587 7.9E-41 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Gene3D G3DSA:1.10.8.500 187 235 5.6E-5 T 15-10-2018 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SMART SM00091 246 312 2.3E-5 T 15-10-2018 IPR000014 PAS domain C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SMART SM00304 187 239 4.2E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Pfam PF00989 PAS fold 247 353 5.7E-11 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Gene3D G3DSA:1.10.287.130 358 433 1.5E-27 T 15-10-2018 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 244 361 6.2E-8 T 15-10-2018 IPR000014 PAS domain C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 Gene3D G3DSA:3.30.450.20 236 357 7.9E-17 T 15-10-2018 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 526 2.6E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 565 2.6E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 584 2.6E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 540 2.6E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SUPERFAMILY SSF158472 189 238 1.96E-7 T 15-10-2018 C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SUPERFAMILY SSF55785 242 354 6.47E-11 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_05380 8ae97206843d986a1bc0289b0770bd5e 590 SUPERFAMILY SSF47384 348 429 9.81E-22 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 149 1.1E-20 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 Gene3D G3DSA:1.10.10.10 92 155 2.7E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 Gene3D G3DSA:1.10.1740.10 1 74 1.0E-10 T 15-10-2018 C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 SUPERFAMILY SSF88946 6 84 1.02E-11 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 SUPERFAMILY SSF88659 88 152 7.1E-13 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 Pfam PF08281 Sigma-70, region 4 102 149 7.1E-14 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_19435 4c42a5d228db21fac23b6bc18baf0d5c 159 Pfam PF04542 Sigma-70 region 2 7 68 1.5E-6 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_07910 08467322af595c9157ecfd492b656da7 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 15-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07910 08467322af595c9157ecfd492b656da7 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.9E-50 T 15-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07910 08467322af595c9157ecfd492b656da7 149 SUPERFAMILY SSF55658 1 56 3.84E-18 T 15-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal C2I28_07910 08467322af595c9157ecfd492b656da7 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.76 T 15-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07910 08467322af595c9157ecfd492b656da7 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 9.6E-22 T 15-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07910 08467322af595c9157ecfd492b656da7 149 SUPERFAMILY SSF55653 57 148 5.76E-29 T 15-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily C2I28_07910 08467322af595c9157ecfd492b656da7 149 Gene3D G3DSA:3.40.5.10 1 52 1.5E-24 T 15-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07910 08467322af595c9157ecfd492b656da7 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 9.6E-31 T 15-10-2018 IPR020069 Ribosomal protein L9, C-terminal C2I28_07910 08467322af595c9157ecfd492b656da7 149 Gene3D G3DSA:3.10.430.100 60 149 4.7E-33 T 15-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 30 211 38.322 T 15-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 35 212 2.0E-69 T 15-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 Pfam PF01227 GTP cyclohydrolase I 36 210 2.6E-72 T 15-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 90 106 - T 15-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 SUPERFAMILY SSF55620 32 211 1.26E-72 T 15-10-2018 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 Gene3D G3DSA:3.30.1130.10 81 214 1.1E-57 T 15-10-2018 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 Gene3D G3DSA:1.10.286.10 15 79 1.4E-15 T 15-10-2018 C2I28_13555 f4f89af847382bd4d6ce2536eba06e73 214 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 138 148 - T 15-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 Gene3D G3DSA:2.40.50.140 1 67 4.6E-25 T 15-10-2018 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 PIRSF PIRSF002599 1 70 1.3E-21 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 1.0E-25 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 SMART SM00357 5 69 6.2E-21 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 SUPERFAMILY SSF50249 3 69 2.67E-20 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 PRINTS PR00050 Cold shock protein signature 42 60 1.1E-14 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 PRINTS PR00050 Cold shock protein signature 6 21 1.1E-14 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25330 a7c4ec5cb27e79b5d6919424fd8a6f54 70 PRINTS PR00050 Cold shock protein signature 27 36 1.1E-14 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_16340 782e06e4ed01fe8c4ddad75f5124df80 436 Gene3D G3DSA:1.20.144.10 333 432 1.5E-14 T 15-10-2018 C2I28_16340 782e06e4ed01fe8c4ddad75f5124df80 436 SUPERFAMILY SSF48317 228 426 4.71E-16 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_16340 782e06e4ed01fe8c4ddad75f5124df80 436 Pfam PF01569 PAP2 superfamily 343 422 8.8E-11 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_16340 782e06e4ed01fe8c4ddad75f5124df80 436 Pfam PF09335 SNARE associated Golgi protein 35 161 1.3E-18 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_26305 f042a984a11fe19a293839a72fab29db 370 Pfam PF13702 Lysozyme-like 63 218 2.4E-50 T 15-10-2018 C2I28_26305 f042a984a11fe19a293839a72fab29db 370 Gene3D G3DSA:3.90.1720.10 217 359 2.3E-32 T 15-10-2018 C2I28_26305 f042a984a11fe19a293839a72fab29db 370 Gene3D G3DSA:1.10.530.10 60 216 6.6E-57 T 15-10-2018 C2I28_26305 f042a984a11fe19a293839a72fab29db 370 Pfam PF00877 NlpC/P60 family 255 361 9.7E-21 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_26305 f042a984a11fe19a293839a72fab29db 370 SUPERFAMILY SSF53955 69 168 8.44E-13 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_26305 f042a984a11fe19a293839a72fab29db 370 SUPERFAMILY SSF54001 240 366 7.36E-25 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_26405 f042a984a11fe19a293839a72fab29db 370 Pfam PF13702 Lysozyme-like 63 218 2.4E-50 T 15-10-2018 C2I28_26405 f042a984a11fe19a293839a72fab29db 370 Gene3D G3DSA:3.90.1720.10 217 359 2.3E-32 T 15-10-2018 C2I28_26405 f042a984a11fe19a293839a72fab29db 370 Gene3D G3DSA:1.10.530.10 60 216 6.6E-57 T 15-10-2018 C2I28_26405 f042a984a11fe19a293839a72fab29db 370 Pfam PF00877 NlpC/P60 family 255 361 9.7E-21 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_26405 f042a984a11fe19a293839a72fab29db 370 SUPERFAMILY SSF53955 69 168 8.44E-13 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_26405 f042a984a11fe19a293839a72fab29db 370 SUPERFAMILY SSF54001 240 366 7.36E-25 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_25095 456f82dc0cf6f8c96458b135ab68aad4 254 Pfam PF02096 60Kd inner membrane protein 60 243 5.9E-47 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_25095 456f82dc0cf6f8c96458b135ab68aad4 254 PRINTS PR00701 60kDa inner membrane protein signature 124 147 1.6E-13 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_25095 456f82dc0cf6f8c96458b135ab68aad4 254 PRINTS PR00701 60kDa inner membrane protein signature 209 232 1.6E-13 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_25095 456f82dc0cf6f8c96458b135ab68aad4 254 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 242 1.5E-51 T 15-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 Gene3D G3DSA:1.20.120.1810 20 126 3.8E-24 T 15-10-2018 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 Gene3D G3DSA:1.10.10.10 160 237 8.0E-14 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 PRINTS PR00046 Major sigma-70 factor signature 197 212 4.4E-13 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 PRINTS PR00046 Major sigma-70 factor signature 78 91 4.4E-13 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 PRINTS PR00046 Major sigma-70 factor signature 176 188 4.4E-13 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 PRINTS PR00046 Major sigma-70 factor signature 212 223 4.4E-13 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 PIRSF PIRSF000770 1 242 4.3E-93 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 223 8.7E-31 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 Pfam PF04545 Sigma-70, region 4 173 223 2.8E-15 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 SUPERFAMILY SSF88946 10 120 1.96E-34 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 SUPERFAMILY SSF88659 139 225 5.45E-19 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 5 228 6.4E-114 T 15-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_04505 574d6499093089ca7ebffa0fd84fba5f 242 Pfam PF04542 Sigma-70 region 2 54 123 9.0E-18 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 Pfam PF01047 MarR family 34 92 2.8E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 SUPERFAMILY SSF46785 12 140 5.46E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 Gene3D G3DSA:1.10.10.10 6 141 6.3E-30 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 1.3E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 1.3E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.3E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_15610 418c0270634ff284439d9c4865e0e3b0 142 SMART SM00347 27 127 3.6E-22 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 TIGRFAM TIGR01391 dnaG: DNA primase 4 420 1.4E-153 T 15-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Pfam PF01807 CHC2 zinc finger 6 99 2.0E-39 T 15-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Hamap MF_00974 DNA primase [dnaG]. 4 592 30.026 T 15-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Gene3D G3DSA:3.90.580.10 1 101 4.4E-43 T 15-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Gene3D G3DSA:3.40.1360.10 244 368 3.4E-40 T 15-10-2018 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Gene3D G3DSA:1.10.860.10 466 561 2.8E-36 T 15-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 SUPERFAMILY SSF48024 462 541 4.32E-6 T 15-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 SMART SM00493 262 333 8.7E-13 T 15-10-2018 IPR006171 TOPRIM domain C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 PIRSF PIRSF002811 2 602 2.6E-193 T 15-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 SUPERFAMILY SSF56731 115 426 2.88E-101 T 15-10-2018 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Pfam PF10410 DnaB-helicase binding domain of primase 371 424 3.1E-12 T 15-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 255 3.1E-43 T 15-10-2018 IPR013264 DNA primase, catalytic core, N-terminal C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 SUPERFAMILY SSF57783 4 98 2.72E-38 T 15-10-2018 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Gene3D G3DSA:3.90.980.10 111 243 4.3E-48 T 15-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 SMART SM00400 36 90 7.5E-37 T 15-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 C2I28_04265 dd1d91ccb2d95f551b1c9c8c38a19d01 602 Pfam PF13155 Toprim-like 265 350 2.9E-19 T 15-10-2018 C2I28_11765 924d46f2902f290d7d4d9d04c8010190 226 Hamap MF_01124 Adapter protein MecA [mecA]. 1 223 27.401 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_11765 924d46f2902f290d7d4d9d04c8010190 226 PIRSF PIRSF029008 1 225 2.7E-73 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_11765 924d46f2902f290d7d4d9d04c8010190 226 Gene3D G3DSA:3.30.70.1950 126 224 6.8E-28 T 15-10-2018 IPR038471 MecA, C-terminal domain superfamily C2I28_11765 924d46f2902f290d7d4d9d04c8010190 226 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 219 3.2E-48 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_07005 f0a7c1a4e208b642c35dd37a744969cc 396 SMART SM00228 280 362 3.2E-7 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_07005 f0a7c1a4e208b642c35dd37a744969cc 396 Gene3D G3DSA:2.30.42.10 278 370 4.6E-12 T 15-10-2018 C2I28_07005 f0a7c1a4e208b642c35dd37a744969cc 396 SUPERFAMILY SSF50156 304 388 1.01E-14 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_04240 fbd363ed1141fc47a7f93b343dace495 373 Gene3D G3DSA:3.30.70.120 134 242 2.9E-42 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_04240 fbd363ed1141fc47a7f93b343dace495 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 7 369 7.7E-98 T 15-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 C2I28_04240 fbd363ed1141fc47a7f93b343dace495 373 PIRSF PIRSF037489 5 373 3.1E-155 T 15-10-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria C2I28_04240 fbd363ed1141fc47a7f93b343dace495 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 351 2.4E-81 T 15-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 C2I28_04240 fbd363ed1141fc47a7f93b343dace495 373 Gene3D G3DSA:3.40.1390.30 7 125 8.6E-41 T 15-10-2018 C2I28_04240 fbd363ed1141fc47a7f93b343dace495 373 SUPERFAMILY SSF102705 8 372 2.62E-131 T 15-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily C2I28_24555 22f60b80c6792808bc5e8defecfa4d45 253 SMART SM00382 32 220 3.0E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_24555 22f60b80c6792808bc5e8defecfa4d45 253 SUPERFAMILY SSF52540 3 225 3.41E-65 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_24555 22f60b80c6792808bc5e8defecfa4d45 253 Pfam PF00005 ABC transporter 23 171 1.1E-29 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_24555 22f60b80c6792808bc5e8defecfa4d45 253 Gene3D G3DSA:3.40.50.300 1 245 2.4E-63 T 15-10-2018 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 Gene3D G3DSA:1.10.287.130 174 258 5.0E-17 T 15-10-2018 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 SUPERFAMILY SSF55874 247 411 1.7E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 SMART SM00387 301 411 7.4E-35 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 5.8E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 5.8E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 5.8E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 5.8E-16 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 SMART SM00388 190 257 4.6E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 Gene3D G3DSA:3.30.565.10 262 411 1.6E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 Pfam PF00512 His Kinase A (phospho-acceptor) domain 192 256 5.6E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 301 411 8.2E-24 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09085 e24fb42a55d794c9c6781bed4090781f 411 SUPERFAMILY SSF47384 178 256 2.35E-14 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 Pfam PF00171 Aldehyde dehydrogenase family 9 290 3.3E-19 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 327 349 - T 15-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 SUPERFAMILY SSF53720 10 420 3.27E-112 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 PIRSF PIRSF000151 2 420 2.0E-176 T 15-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 9 420 41.112 T 15-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 Gene3D G3DSA:3.40.605.10 22 415 4.5E-165 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 Gene3D G3DSA:3.40.309.10 230 378 4.5E-165 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_19515 2e76bc506f9d349a6b62636ffd20a87a 420 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 17 410 1.3E-156 T 15-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 530 628 2.3E-19 T 15-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Gene3D G3DSA:2.60.40.10 8 132 7.7E-44 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 14 629 40.217 T 15-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 SUPERFAMILY SSF51011 525 629 1.92E-29 T 15-10-2018 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Gene3D G3DSA:3.20.20.80 135 524 1.2E-148 T 15-10-2018 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 20 627 3.2E-266 T 15-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 SUPERFAMILY SSF51445 91 518 6.24E-109 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 SMART SM00642 167 514 1.0E-7 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 PIRSF PIRSF000463 7 639 7.1E-261 T 15-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Gene3D G3DSA:2.60.40.1180 525 630 1.3E-32 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 36 118 1.7E-22 T 15-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I28_06045 b3043869e0b84a81f6e32327ded58d09 653 Pfam PF00128 Alpha amylase, catalytic domain 187 288 5.0E-12 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_10670 060de94664a50940756f82d954348f4a 238 Pfam PF01479 S4 domain 5 49 5.4E-15 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_10670 060de94664a50940756f82d954348f4a 238 Gene3D G3DSA:3.30.70.1560 129 202 3.8E-54 T 15-10-2018 C2I28_10670 060de94664a50940756f82d954348f4a 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 221 2.8E-47 T 15-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I28_10670 060de94664a50940756f82d954348f4a 238 SUPERFAMILY SSF55120 61 225 4.8E-40 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_10670 060de94664a50940756f82d954348f4a 238 SUPERFAMILY SSF55174 4 77 2.52E-14 T 15-10-2018 C2I28_10670 060de94664a50940756f82d954348f4a 238 SMART SM00363 4 64 3.9E-13 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_10670 060de94664a50940756f82d954348f4a 238 Pfam PF00849 RNA pseudouridylate synthase 64 189 1.4E-14 T 15-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_10670 060de94664a50940756f82d954348f4a 238 Gene3D G3DSA:3.10.290.10 3 57 5.7E-22 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_10670 060de94664a50940756f82d954348f4a 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 15-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I28_10670 060de94664a50940756f82d954348f4a 238 Gene3D G3DSA:3.30.70.580 65 223 3.8E-54 T 15-10-2018 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 SUPERFAMILY SSF52540 332 579 5.07E-96 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 SUPERFAMILY SSF90123 6 325 7.46E-78 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 Gene3D G3DSA:3.40.50.300 332 582 1.7E-91 T 15-10-2018 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 Gene3D G3DSA:1.20.1560.10 4 325 1.9E-109 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 Pfam PF00664 ABC transporter transmembrane region 24 294 4.8E-44 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 Pfam PF00005 ABC transporter 360 508 5.4E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_10120 f80c3cf4435e1776071ff26e3fe69b77 583 SMART SM00382 368 554 7.3E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 SMART SM00850 148 245 3.3E-37 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 SUPERFAMILY SSF52172 1 121 2.7E-30 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 Pfam PF00072 Response regulator receiver domain 4 113 1.4E-23 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 Gene3D G3DSA:2.40.50.40 139 208 1.6E-15 T 15-10-2018 C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 Pfam PF04397 LytTr DNA-binding domain 149 244 1.7E-31 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 Gene3D G3DSA:3.40.50.2300 1 126 4.1E-32 T 15-10-2018 C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 Gene3D G3DSA:2.20.25.10 209 246 2.8E-9 T 15-10-2018 C2I28_12075 f22527d55cd6900f27d89f92ca7cace9 246 SMART SM00448 2 113 1.1E-24 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03420 610dad04fb59296d9aaf70d3dfe5df56 173 Pfam PF00578 AhpC/TSA family 37 152 8.6E-38 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_03420 610dad04fb59296d9aaf70d3dfe5df56 173 Gene3D G3DSA:3.40.30.10 24 172 1.2E-51 T 15-10-2018 C2I28_03420 610dad04fb59296d9aaf70d3dfe5df56 173 SUPERFAMILY SSF52833 9 170 1.44E-46 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 SUPERFAMILY SSF52096 9 228 9.95E-32 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 Pfam PF01039 Carboxyl transferase domain 14 278 2.0E-13 T 15-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 SUPERFAMILY SSF52096 377 491 9.02E-15 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 6 277 1.2E-108 T 15-10-2018 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 304 558 2.2E-69 T 15-10-2018 C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 Gene3D G3DSA:3.90.226.10 4 238 6.5E-46 T 15-10-2018 C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 300 564 1.1E-86 T 15-10-2018 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 C2I28_12175 a297a59578a93c4f411bb1fc71faff86 566 Gene3D G3DSA:3.90.226.10 329 544 1.7E-22 T 15-10-2018 C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 Pfam PF04542 Sigma-70 region 2 10 76 1.5E-14 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 SUPERFAMILY SSF88659 107 159 1.01E-11 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 7 160 2.5E-56 T 15-10-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 159 2.2E-26 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 Pfam PF08281 Sigma-70, region 4 111 156 5.5E-12 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 Gene3D G3DSA:1.10.10.10 107 163 3.4E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 Gene3D G3DSA:1.10.1740.10 1 79 8.4E-21 T 15-10-2018 C2I28_18655 03616cf59668a7678f3d5e91ac5f931f 164 SUPERFAMILY SSF88946 4 93 9.42E-21 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 PIRSF PIRSF000139 13 446 6.0E-151 T 15-10-2018 C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 SUPERFAMILY SSF46548 23 112 3.5E-18 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 Pfam PF02754 Cysteine-rich domain 205 286 1.4E-14 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 Pfam PF02754 Cysteine-rich domain 333 416 1.3E-11 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 Pfam PF13183 4Fe-4S dicluster domain 32 98 1.6E-11 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 Gene3D G3DSA:1.10.1060.10 10 116 1.1E-9 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_22485 caa63279405b95beacb3bf4dc3bc5e8b 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 127 1.6E-16 T 15-10-2018 IPR000014 PAS domain C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 SMART SM00382 173 317 3.6E-9 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Pfam PF00158 Sigma-54 interaction domain 154 320 4.3E-68 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Gene3D G3DSA:3.30.450.20 4 137 3.0E-20 T 15-10-2018 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 SUPERFAMILY SSF46689 405 454 1.34E-8 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Gene3D G3DSA:3.40.50.300 138 325 4.6E-63 T 15-10-2018 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 SUPERFAMILY SSF55785 12 119 1.08E-15 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 SUPERFAMILY SSF52540 153 395 7.61E-67 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Gene3D G3DSA:1.10.10.60 403 456 7.7E-8 T 15-10-2018 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Pfam PF02954 Bacterial regulatory protein, Fis family 414 453 4.1E-6 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Pfam PF13426 PAS domain 24 120 3.5E-11 T 15-10-2018 IPR000014 PAS domain C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 SMART SM00091 13 79 3.1E-6 T 15-10-2018 IPR000014 PAS domain C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 240 255 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_22010 ee0614df50f9cdf5b1422ef33c8f54e9 462 Gene3D G3DSA:1.10.8.60 326 401 9.0E-21 T 15-10-2018 C2I28_26030 f6e498b257a51655cd91b8b788719a27 477 Gene3D G3DSA:3.40.605.10 23 472 7.6E-159 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_26030 f6e498b257a51655cd91b8b788719a27 477 Gene3D G3DSA:3.40.309.10 256 443 7.6E-159 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_26030 f6e498b257a51655cd91b8b788719a27 477 Pfam PF00171 Aldehyde dehydrogenase family 20 471 4.4E-162 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_26030 f6e498b257a51655cd91b8b788719a27 477 SUPERFAMILY SSF53720 5 476 2.49E-150 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_13415 8a6ae9289f1f9a1607067335fdfee2da 307 Gene3D G3DSA:3.40.50.2300 1 133 3.8E-22 T 15-10-2018 C2I28_13415 8a6ae9289f1f9a1607067335fdfee2da 307 Pfam PF08664 YcbB domain 161 299 2.1E-47 T 15-10-2018 IPR013972 YcbB domain C2I28_13415 8a6ae9289f1f9a1607067335fdfee2da 307 SUPERFAMILY SSF52172 2 135 1.57E-23 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_13415 8a6ae9289f1f9a1607067335fdfee2da 307 Pfam PF00072 Response regulator receiver domain 4 112 6.1E-18 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_13415 8a6ae9289f1f9a1607067335fdfee2da 307 SMART SM00448 1 114 2.2E-17 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_06800 06a86e54e050cd8f8fc5e1416d839a25 246 Gene3D G3DSA:3.40.50.1820 1 246 1.1E-62 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06800 06a86e54e050cd8f8fc5e1416d839a25 246 Pfam PF12146 Serine aminopeptidase, S33 16 229 2.7E-18 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_06800 06a86e54e050cd8f8fc5e1416d839a25 246 PIRSF PIRSF017388 1 246 6.5E-96 T 15-10-2018 IPR012354 Esterase/lipase GO:0052689 C2I28_06800 06a86e54e050cd8f8fc5e1416d839a25 246 SUPERFAMILY SSF53474 12 245 1.26E-35 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11815 681316f892e6ce7e616cfe706aefd703 211 Pfam PF04607 Region found in RelA / SpoT proteins 44 163 2.2E-38 T 15-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I28_11815 681316f892e6ce7e616cfe706aefd703 211 Gene3D G3DSA:1.10.287.860 148 211 1.4E-29 T 15-10-2018 C2I28_11815 681316f892e6ce7e616cfe706aefd703 211 Gene3D G3DSA:3.30.460.10 2 147 5.1E-52 T 15-10-2018 C2I28_11815 681316f892e6ce7e616cfe706aefd703 211 SMART SM00954 44 165 1.6E-41 T 15-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I28_11815 681316f892e6ce7e616cfe706aefd703 211 SUPERFAMILY SSF81301 5 198 6.87E-61 T 15-10-2018 C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 SUPERFAMILY SSF56784 4 283 1.27E-59 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 278 3.3E-56 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 Gene3D G3DSA:3.40.50.1000 6 274 4.8E-65 T 15-10-2018 IPR023214 HAD superfamily C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 Gene3D G3DSA:3.30.1240.10 84 206 4.8E-65 T 15-10-2018 C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 250 7.7E-28 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 ProSitePatterns PS01228 Hypothetical cof family signature 1. 7 18 - T 15-10-2018 C2I28_22415 2fe1affdf3a2dcbcec7f52e4095db11a 293 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 278 1.5E-56 T 15-10-2018 C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 Pfam PF07486 Cell Wall Hydrolase 92 189 5.8E-27 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 Gene3D G3DSA:2.40.10.420 158 191 5.9E-12 T 15-10-2018 C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 Pfam PF01476 LysM domain 29 71 5.4E-11 T 15-10-2018 IPR018392 LysM domain C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 SUPERFAMILY SSF54106 27 71 1.44E-9 T 15-10-2018 C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 Gene3D G3DSA:1.10.10.2520 79 154 1.2E-31 T 15-10-2018 C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 SMART SM00257 28 71 2.2E-13 T 15-10-2018 IPR018392 LysM domain C2I28_18555 3b3f8f0502880c59a2ceaba9e7165ae5 191 Gene3D G3DSA:3.10.350.10 18 78 2.8E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 Gene3D G3DSA:3.30.60.20 142 194 7.2E-27 T 15-10-2018 C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 Pfam PF00265 Thymidine kinase 8 187 9.1E-61 T 15-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 Gene3D G3DSA:3.40.50.300 1 141 1.6E-61 T 15-10-2018 C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 SUPERFAMILY SSF57716 142 192 3.18E-16 T 15-10-2018 C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 SUPERFAMILY SSF52540 8 142 1.97E-45 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.4 T 15-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 PIRSF PIRSF035805 5 201 1.6E-69 T 15-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I28_07425 a3e6f756d7b2472eca036a8b43b61ee4 207 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 15-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 SMART SM00493 80 165 4.6E-18 T 15-10-2018 IPR006171 TOPRIM domain C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 Gene3D G3DSA:3.40.1360.10 77 198 5.3E-50 T 15-10-2018 C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 SUPERFAMILY SSF111304 2 198 6.15E-79 T 15-10-2018 IPR023627 Recombination protein RecR C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 Pfam PF13662 Toprim domain 80 171 1.5E-26 T 15-10-2018 IPR006171 TOPRIM domain C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 2.7E-91 T 15-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 111.139 T 15-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 Gene3D G3DSA:1.10.8.420 1 53 1.1E-19 T 15-10-2018 C2I28_08145 f1f7f9628d99b0c6ea15d74ef470ebc5 198 Pfam PF02132 RecR protein 40 77 5.3E-17 T 15-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger C2I28_23260 3520316219c78fcc6440dfe4a4c79e31 382 SUPERFAMILY SSF52402 252 373 1.93E-13 T 15-10-2018 C2I28_23260 3520316219c78fcc6440dfe4a4c79e31 382 Gene3D G3DSA:3.40.50.620 239 374 9.4E-13 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_23260 3520316219c78fcc6440dfe4a4c79e31 382 SUPERFAMILY SSF52540 33 147 1.24E-7 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23260 3520316219c78fcc6440dfe4a4c79e31 382 Pfam PF00582 Universal stress protein family 252 367 2.4E-8 T 15-10-2018 IPR006016 UspA C2I28_23260 3520316219c78fcc6440dfe4a4c79e31 382 Gene3D G3DSA:3.40.50.300 24 234 4.8E-90 T 15-10-2018 C2I28_23260 3520316219c78fcc6440dfe4a4c79e31 382 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 26 235 2.3E-91 T 15-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 C2I28_25240 0e3a6d0102494a2e895ec09c514e18a6 180 Pfam PF02796 Helix-turn-helix domain of resolvase 137 178 3.1E-9 T 15-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 C2I28_25240 0e3a6d0102494a2e895ec09c514e18a6 180 Pfam PF00239 Resolvase, N terminal domain 2 134 5.6E-27 T 15-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I28_25240 0e3a6d0102494a2e895ec09c514e18a6 180 SUPERFAMILY SSF53041 2 134 3.92E-27 T 15-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 C2I28_25240 0e3a6d0102494a2e895ec09c514e18a6 180 SMART SM00857 2 135 1.7E-26 T 15-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I28_25240 0e3a6d0102494a2e895ec09c514e18a6 180 SUPERFAMILY SSF46689 137 178 3.31E-5 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_25240 0e3a6d0102494a2e895ec09c514e18a6 180 Gene3D G3DSA:3.40.50.1390 1 124 2.0E-27 T 15-10-2018 C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Gene3D G3DSA:1.20.1260.110 146 291 2.0E-41 T 15-10-2018 IPR038331 DisA, linker domain superfamily C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 28 139 4.1E-26 T 15-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Pfam PF00633 Helix-hairpin-helix motif 318 344 1.2E-5 T 15-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 SUPERFAMILY SSF47781 279 354 5.56E-13 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Gene3D G3DSA:1.10.150.20 292 356 1.1E-23 T 15-10-2018 C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Pfam PF10635 DisA bacterial checkpoint controller linker region 145 281 2.5E-48 T 15-10-2018 IPR018906 DNA integrity scanning, DisA, linker region C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 8 356 44.22 T 15-10-2018 IPR023763 DNA integrity scanning protein, DisA C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 SUPERFAMILY SSF143597 17 145 1.27E-29 T 15-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I28_08550 32bdfcc5a6a43a86aeffead455a70f85 359 Gene3D G3DSA:3.40.1700.10 9 145 9.1E-56 T 15-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 SMART SM00345 8 67 2.0E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 6.1E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 6.1E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 SMART SM00866 88 227 4.7E-28 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 SUPERFAMILY SSF64288 77 228 7.22E-39 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 Gene3D G3DSA:3.40.1410.10 72 230 5.8E-38 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 Pfam PF07702 UTRA domain 93 226 2.1E-31 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 Gene3D G3DSA:1.10.10.10 1 67 2.1E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 SUPERFAMILY SSF46785 2 71 8.33E-18 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16460 62a9164aa6525e873e7f6d92bea45a8f 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 7.5E-12 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 Pfam PF03705 CheR methyltransferase, all-alpha domain 3 54 3.7E-14 T 15-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal C2I28_03205 0f3257226fd1a4f21879105a10783045 260 Gene3D G3DSA:1.10.155.10 2 66 2.0E-5 T 15-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily C2I28_03205 0f3257226fd1a4f21879105a10783045 260 Pfam PF01739 CheR methyltransferase, SAM binding domain 68 244 4.0E-58 T 15-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal C2I28_03205 0f3257226fd1a4f21879105a10783045 260 PRINTS PR00996 Glutamate methyltransferase family signature 196 210 6.5E-41 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 PRINTS PR00996 Glutamate methyltransferase family signature 61 73 6.5E-41 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 PRINTS PR00996 Glutamate methyltransferase family signature 24 37 6.5E-41 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 PRINTS PR00996 Glutamate methyltransferase family signature 130 146 6.5E-41 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 PRINTS PR00996 Glutamate methyltransferase family signature 98 118 6.5E-41 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 PRINTS PR00996 Glutamate methyltransferase family signature 215 238 6.5E-41 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 SMART SM00138 2 255 5.0E-98 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 Gene3D G3DSA:3.40.50.150 67 257 3.5E-64 T 15-10-2018 C2I28_03205 0f3257226fd1a4f21879105a10783045 260 SUPERFAMILY SSF53335 68 252 4.51E-49 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_03205 0f3257226fd1a4f21879105a10783045 260 SUPERFAMILY SSF47757 4 67 8.76E-14 T 15-10-2018 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 SMART SM00646 63 176 6.0E-38 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 SUPERFAMILY SSF54106 187 233 3.27E-12 T 15-10-2018 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 SUPERFAMILY SSF54106 234 279 6.93E-13 T 15-10-2018 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 SMART SM00257 188 232 9.6E-18 T 15-10-2018 IPR018392 LysM domain C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 SMART SM00257 235 279 1.4E-18 T 15-10-2018 IPR018392 LysM domain C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 SUPERFAMILY SSF53187 1 181 6.91E-48 T 15-10-2018 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 Gene3D G3DSA:3.40.630.40 1 183 2.0E-50 T 15-10-2018 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 Gene3D G3DSA:3.10.350.10 186 232 5.3E-22 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 Gene3D G3DSA:3.10.350.10 233 279 9.0E-24 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 176 4.1E-42 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 Pfam PF01476 LysM domain 189 232 6.8E-14 T 15-10-2018 IPR018392 LysM domain C2I28_23810 901097c292f5b39c216b9dbe26fa3155 281 Pfam PF01476 LysM domain 236 279 5.7E-15 T 15-10-2018 IPR018392 LysM domain C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 Gene3D G3DSA:3.40.50.880 245 457 4.1E-12 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 Gene3D G3DSA:3.40.50.300 4 189 2.0E-25 T 15-10-2018 C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 448 5.2E-142 T 15-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 SUPERFAMILY SSF52317 246 449 1.12E-32 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 248 438 1.7E-39 T 15-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 192 6.5E-24 T 15-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 SUPERFAMILY SSF52540 1 195 9.39E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21170 c5c7f99b13451de88c58bb8d74b895b5 460 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 439 46.131 T 15-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 C2I28_15670 aa4e8156fc6939725a17bf8c8579c6aa 161 SUPERFAMILY SSF54637 5 150 3.05E-25 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_15670 aa4e8156fc6939725a17bf8c8579c6aa 161 Pfam PF03061 Thioesterase superfamily 56 140 3.4E-5 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_15670 aa4e8156fc6939725a17bf8c8579c6aa 161 Gene3D G3DSA:3.10.129.10 3 158 2.7E-36 T 15-10-2018 C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 121 287 2.6E-45 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 Gene3D G3DSA:2.30.30.40 28 92 1.3E-14 T 15-10-2018 C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 SMART SM00646 178 287 4.4E-24 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 Gene3D G3DSA:3.40.630.40 117 296 3.3E-54 T 15-10-2018 C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 Pfam PF08239 Bacterial SH3 domain 37 85 8.2E-10 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 SUPERFAMILY SSF53187 118 291 3.45E-47 T 15-10-2018 C2I28_04695 cd288b7c895f8f1cee90c2ff5a7f430c 300 SMART SM00287 28 90 1.9E-8 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 Gene3D G3DSA:3.40.50.12740 3 224 5.5E-71 T 15-10-2018 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 SUPERFAMILY SSF46894 150 225 1.77E-24 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 2.1E-23 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 SMART SM00421 161 218 1.7E-28 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 SUPERFAMILY SSF52172 2 133 1.07E-34 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 1.4E-14 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 1.4E-14 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 1.4E-14 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 Pfam PF00072 Response regulator receiver domain 5 117 6.9E-33 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 SMART SM00448 3 116 2.8E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07180 e3ac92c874e8269b5297ebf807aa5111 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_22710 c60210e0b61d5c73784f7a069de18dfb 132 Gene3D G3DSA:1.10.10.10 18 128 4.6E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22710 c60210e0b61d5c73784f7a069de18dfb 132 SUPERFAMILY SSF46785 36 114 3.79E-12 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_22710 c60210e0b61d5c73784f7a069de18dfb 132 Pfam PF03551 Transcriptional regulator PadR-like family 45 111 1.5E-12 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Pfam PF01380 SIS domain 289 413 4.5E-35 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Pfam PF01380 SIS domain 457 582 1.0E-17 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 1.0E-230 T 15-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Gene3D G3DSA:3.60.20.10 2 239 2.3E-73 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 39.168 T 15-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 SUPERFAMILY SSF53697 244 600 7.33E-95 T 15-10-2018 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Gene3D G3DSA:3.40.50.10490 444 600 3.1E-61 T 15-10-2018 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Gene3D G3DSA:3.40.50.10490 243 442 2.9E-65 T 15-10-2018 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 Pfam PF13522 Glutamine amidotransferase domain 57 192 6.9E-23 T 15-10-2018 C2I28_08995 77479f519bbc957aeec65f932c96ab9a 600 SUPERFAMILY SSF56235 2 235 1.03E-66 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_23490 95985fad1b6f224789642fef174e352e 327 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 15-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 C2I28_23490 95985fad1b6f224789642fef174e352e 327 Gene3D G3DSA:3.40.50.1170 2 199 6.1E-67 T 15-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 Pfam PF00710 Asparaginase, N-terminal 3 185 5.2E-64 T 15-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 327 8.6E-128 T 15-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 SMART SM00870 3 315 8.7E-107 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 Gene3D G3DSA:3.40.50.40 200 327 2.4E-35 T 15-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 SUPERFAMILY SSF53774 2 326 1.83E-96 T 15-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 PIRSF PIRSF001220 1 326 1.1E-93 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 PRINTS PR00139 Asparaginase/glutaminase family signature 252 270 6.5E-15 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 6.5E-15 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 6.5E-15 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_23490 95985fad1b6f224789642fef174e352e 327 PIRSF PIRSF500176 1 324 4.0E-101 T 15-10-2018 C2I28_23490 95985fad1b6f224789642fef174e352e 327 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 15-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 Pfam PF16657 Maltogenic Amylase, C-terminal domain 377 448 1.1E-6 T 15-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 SUPERFAMILY SSF51011 377 456 2.88E-11 T 15-10-2018 C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 SUPERFAMILY SSF51445 25 377 1.39E-62 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 Pfam PF00128 Alpha amylase, catalytic domain 63 135 8.4E-27 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 Pfam PF00128 Alpha amylase, catalytic domain 143 341 2.1E-6 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 SMART SM00642 35 368 3.9E-30 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 Gene3D G3DSA:3.20.20.80 22 372 5.3E-87 T 15-10-2018 C2I28_11460 765a7f04653bde1ea8e922a8b97e61d1 504 Gene3D G3DSA:2.60.40.1180 373 468 1.2E-27 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 4.7E-23 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 280 4.7E-23 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 245 254 4.7E-23 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 44 63 4.7E-23 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 Gene3D G3DSA:3.40.50.1370 6 288 6.6E-102 T 15-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 294 39.02 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 292 1.4E-95 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 44 51 - T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 289 3.9E-25 T 15-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 140 1.6E-40 T 15-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 72 81 3.1E-32 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 208 217 3.1E-32 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 249 254 3.1E-32 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 34 56 3.1E-32 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 127 144 3.1E-32 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 PRINTS PR00101 Aspartate carbamoyltransferase signature 273 287 3.1E-32 T 15-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 SUPERFAMILY SSF53671 1 293 1.7E-91 T 15-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I28_02850 fb8d52e70d057510779923d4b91ce7a3 312 Gene3D G3DSA:3.40.50.1370 128 271 6.6E-102 T 15-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I28_00470 929f761e776dafd7599d377fe7c55772 172 Hamap MF_01256 Putative metal-dependent hydrolase . 1 172 34.922 T 15-10-2018 IPR023774 Putative metal-dependent hydrolase YfiT C2I28_00470 929f761e776dafd7599d377fe7c55772 172 SUPERFAMILY SSF109854 4 172 1.22E-44 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_00470 929f761e776dafd7599d377fe7c55772 172 Pfam PF12867 DinB superfamily 31 163 9.0E-20 T 15-10-2018 IPR024775 DinB-like domain C2I28_00470 929f761e776dafd7599d377fe7c55772 172 Gene3D G3DSA:1.20.120.450 2 172 6.0E-51 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 SUPERFAMILY SSF51338 13 356 5.7E-18 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 SUPERFAMILY SSF51556 73 320 1.13E-41 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 Pfam PF01979 Amidohydrolase family 68 342 2.8E-30 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 Hamap MF_01518 Adenine deaminase [ade]. 22 575 39.283 T 15-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 TIGRFAM TIGR01178 ade: adenine deaminase 22 574 9.9E-199 T 15-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 Gene3D G3DSA:2.30.40.10 14 352 2.6E-129 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 Pfam PF00449 Urease alpha-subunit, N-terminal domain 13 63 4.4E-5 T 15-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 Gene3D G3DSA:3.20.20.140 72 315 2.6E-129 T 15-10-2018 C2I28_09920 c952b5d45dd3da2285ce4bc4312ab8ee 578 Pfam PF13382 Adenine deaminase C-terminal domain 404 572 3.8E-64 T 15-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SMART SM00873 221 394 1.9E-93 T 15-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SUPERFAMILY SSF55681 475 697 3.73E-48 T 15-10-2018 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SUPERFAMILY SSF46955 411 483 1.74E-20 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Gene3D G3DSA:3.50.40.10 204 405 2.7E-84 T 15-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Gene3D G3DSA:3.30.70.380 711 804 3.4E-32 T 15-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Pfam PF03483 B3/4 domain 222 393 1.2E-69 T 15-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Gene3D G3DSA:3.30.56.10 411 483 5.6E-26 T 15-10-2018 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Pfam PF01588 Putative tRNA binding domain 46 152 3.6E-28 T 15-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SUPERFAMILY SSF50249 36 199 2.69E-48 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Gene3D G3DSA:3.30.56.10 4 189 1.9E-72 T 15-10-2018 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 1.0E-20 T 15-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SMART SM00896 710 803 6.4E-47 T 15-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 4.7E-29 T 15-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Gene3D G3DSA:3.30.930.10 495 698 9.0E-61 T 15-10-2018 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 3.2E-275 T 15-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SUPERFAMILY SSF56037 209 406 2.88E-74 T 15-10-2018 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Gene3D G3DSA:2.40.50.140 40 161 1.9E-72 T 15-10-2018 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SUPERFAMILY SSF54991 705 803 2.09E-32 T 15-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 46.465 T 15-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 C2I28_05265 02ac4bb67107f2cc9183e8404e008ab8 804 SMART SM00874 411 479 3.3E-28 T 15-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 Gene3D G3DSA:1.10.10.10 106 164 1.5E-10 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 Gene3D G3DSA:1.10.1740.10 2 85 4.5E-9 T 15-10-2018 C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 SUPERFAMILY SSF88659 109 161 8.04E-11 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 Pfam PF04542 Sigma-70 region 2 20 83 2.0E-6 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 SUPERFAMILY SSF88946 14 93 1.18E-10 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 160 3.8E-13 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_00660 e79d08cd647ad490a0af1af3e743fb7b 221 Pfam PF08281 Sigma-70, region 4 108 158 2.1E-10 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_21460 192521f0e06a93aa2601aff162ada288 291 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 35 260 1.1E-47 T 15-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I28_21460 192521f0e06a93aa2601aff162ada288 291 SUPERFAMILY SSF51695 31 261 1.5E-74 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_21460 192521f0e06a93aa2601aff162ada288 291 Gene3D G3DSA:3.20.20.190 16 269 4.2E-84 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_14030 8f6cab9cc11115f0e1eb6e7e01b8aa75 288 SUPERFAMILY SSF110857 134 262 2.49E-18 T 15-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily C2I28_14030 8f6cab9cc11115f0e1eb6e7e01b8aa75 288 SUPERFAMILY SSF110857 2 126 2.35E-26 T 15-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily C2I28_14030 8f6cab9cc11115f0e1eb6e7e01b8aa75 288 Gene3D G3DSA:3.10.490.10 2 126 2.7E-30 T 15-10-2018 C2I28_14030 8f6cab9cc11115f0e1eb6e7e01b8aa75 288 Pfam PF13772 AIG2-like family 192 273 1.9E-11 T 15-10-2018 C2I28_14030 8f6cab9cc11115f0e1eb6e7e01b8aa75 288 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 124 2.7E-22 T 15-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like C2I28_14030 8f6cab9cc11115f0e1eb6e7e01b8aa75 288 Gene3D G3DSA:3.10.490.10 129 287 1.3E-59 T 15-10-2018 C2I28_10125 a9ed51635f252d028165ac3df77a6956 362 Pfam PF06081 Aromatic acid exporter family member 1 1 142 1.6E-40 T 15-10-2018 IPR010343 Aromatic acid exporter family member 1 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 1.2E-137 T 15-10-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 15-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 SUPERFAMILY SSF53335 3 229 2.74E-49 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.4E-104 T 15-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 1.3E-82 T 15-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 15-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.148 T 15-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 C2I28_03220 90dcfa66c0d5a62ec7cd2f22bb6a6aab 234 Gene3D G3DSA:3.40.50.150 15 234 4.0E-67 T 15-10-2018 C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF03707 Bacterial signalling protein N terminal repeat 58 112 6.1E-17 T 15-10-2018 IPR005330 MHYT domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF03707 Bacterial signalling protein N terminal repeat 188 242 4.4E-7 T 15-10-2018 IPR005330 MHYT domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF03707 Bacterial signalling protein N terminal repeat 121 168 4.7E-12 T 15-10-2018 IPR005330 MHYT domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SUPERFAMILY SSF55785 351 477 4.19E-14 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF00990 Diguanylate cyclase, GGDEF domain 490 646 4.6E-46 T 15-10-2018 IPR000160 GGDEF domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF00989 PAS fold 258 308 1.3E-5 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 486 647 1.1E-43 T 15-10-2018 IPR000160 GGDEF domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Gene3D G3DSA:3.30.450.20 351 477 3.7E-18 T 15-10-2018 C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SUPERFAMILY SSF141868 665 913 4.71E-88 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SUPERFAMILY SSF55073 495 652 9.42E-48 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 364 486 1.7E-16 T 15-10-2018 IPR000014 PAS domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Gene3D G3DSA:3.30.70.270 485 663 2.2E-58 T 15-10-2018 C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF00563 EAL domain 668 901 1.5E-69 T 15-10-2018 IPR001633 EAL domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Gene3D G3DSA:3.30.450.20 248 350 9.4E-9 T 15-10-2018 C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SUPERFAMILY SSF55785 264 360 3.77E-8 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Pfam PF13426 PAS domain 378 478 2.6E-8 T 15-10-2018 IPR000014 PAS domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 Gene3D G3DSA:3.20.20.450 664 913 1.7E-97 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SMART SM00052 660 906 2.7E-109 T 15-10-2018 IPR001633 EAL domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SMART SM00267 479 650 1.5E-62 T 15-10-2018 IPR000160 GGDEF domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SMART SM00091 257 319 21.0 T 15-10-2018 IPR000014 PAS domain C2I28_15440 bb7f0809657e34c5bb88bea88ebf4f96 922 SMART SM00091 365 430 8.0E-8 T 15-10-2018 IPR000014 PAS domain C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 15-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 1.3E-41 T 15-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 SUPERFAMILY SSF46977 444 584 4.45E-44 T 15-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 Pfam PF00890 FAD binding domain 6 392 1.9E-87 T 15-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 3.9E-282 T 15-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 Gene3D G3DSA:3.50.50.60 6 403 1.5E-124 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 Gene3D G3DSA:1.20.58.100 422 539 4.7E-34 T 15-10-2018 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 Gene3D G3DSA:3.90.700.10 258 367 1.5E-124 T 15-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 PIRSF PIRSF000171 341 577 1.7E-15 T 15-10-2018 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 PIRSF PIRSF000171 1 240 1.3E-19 T 15-10-2018 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 SUPERFAMILY SSF51905 6 426 5.68E-64 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 SUPERFAMILY SSF56425 231 353 4.49E-31 T 15-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 9.1E-6 T 15-10-2018 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 9.1E-6 T 15-10-2018 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.3E-8 T 15-10-2018 C2I28_05170 d4df0ed70d48a9b0b01b889045275da9 595 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 2.3E-8 T 15-10-2018 C2I28_21805 146656b21a07ad5c27f2947dcd03115c 500 SUPERFAMILY SSF51905 6 274 4.14E-23 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_21805 146656b21a07ad5c27f2947dcd03115c 500 Gene3D G3DSA:3.30.9.10 113 178 1.6E-6 T 15-10-2018 C2I28_21805 146656b21a07ad5c27f2947dcd03115c 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 2.8E-240 T 15-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I28_21805 146656b21a07ad5c27f2947dcd03115c 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.741 T 15-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I28_21805 146656b21a07ad5c27f2947dcd03115c 500 Gene3D G3DSA:3.50.50.60 10 256 1.6E-6 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_21805 146656b21a07ad5c27f2947dcd03115c 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 1.3E-220 T 15-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I28_01025 f4791b5b26773ce26f15b0930c491ce4 176 Pfam PF01047 MarR family 44 101 4.5E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_01025 f4791b5b26773ce26f15b0930c491ce4 176 Gene3D G3DSA:1.10.10.10 2 167 1.5E-38 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01025 f4791b5b26773ce26f15b0930c491ce4 176 SUPERFAMILY SSF46785 22 130 1.1E-18 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_01025 f4791b5b26773ce26f15b0930c491ce4 176 SMART SM00347 37 137 3.4E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_09760 54bb333f223e9b7e038cbb6d16a11396 151 Pfam PF02915 Rubrerythrin 27 144 4.3E-9 T 15-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 C2I28_09760 54bb333f223e9b7e038cbb6d16a11396 151 SUPERFAMILY SSF47240 18 145 1.13E-20 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_09760 54bb333f223e9b7e038cbb6d16a11396 151 Gene3D G3DSA:1.20.120.660 88 150 2.3E-5 T 15-10-2018 C2I28_09760 54bb333f223e9b7e038cbb6d16a11396 151 Gene3D G3DSA:1.20.120.660 9 87 1.8E-7 T 15-10-2018 C2I28_02080 c498c6a001d7dff7fee8b800cc1c8153 203 Pfam PF03458 UPF0126 domain 92 160 4.0E-18 T 15-10-2018 IPR005115 Uncharacterised domain UPF0126 C2I28_02080 c498c6a001d7dff7fee8b800cc1c8153 203 Pfam PF03458 UPF0126 domain 5 78 1.5E-18 T 15-10-2018 IPR005115 Uncharacterised domain UPF0126 C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 PIRSF PIRSF000094 4 259 7.5E-100 T 15-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 256 1.3E-81 T 15-10-2018 C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 SUPERFAMILY SSF51735 8 258 1.7E-63 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 Gene3D G3DSA:1.10.8.400 206 259 2.8E-16 T 15-10-2018 C2I28_24655 385578c8d16e48afa5a3674e3a43ada4 259 Gene3D G3DSA:3.40.50.720 11 205 1.1E-38 T 15-10-2018 C2I28_07720 214e02915e95b001474788eeb572223e 570 SUPERFAMILY SSF52540 323 565 4.75E-69 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07720 214e02915e95b001474788eeb572223e 570 Pfam PF00005 ABC transporter 349 497 7.7E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_07720 214e02915e95b001474788eeb572223e 570 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 12 538 2.7E-170 T 15-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 C2I28_07720 214e02915e95b001474788eeb572223e 570 Gene3D G3DSA:3.40.50.300 317 568 3.1E-74 T 15-10-2018 C2I28_07720 214e02915e95b001474788eeb572223e 570 SMART SM00382 358 543 3.7E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_07720 214e02915e95b001474788eeb572223e 570 Gene3D G3DSA:1.20.1560.10 3 316 2.4E-37 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_07720 214e02915e95b001474788eeb572223e 570 SUPERFAMILY SSF90123 12 481 6.41E-47 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_07720 214e02915e95b001474788eeb572223e 570 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_07720 214e02915e95b001474788eeb572223e 570 Pfam PF00664 ABC transporter transmembrane region 17 278 2.2E-27 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_25250 7c768e1ca5b16b8ef8866a71c743e094 127 SUPERFAMILY SSF103247 1 124 1.83E-35 T 15-10-2018 IPR035923 TT1751-like domain superfamily C2I28_25250 7c768e1ca5b16b8ef8866a71c743e094 127 Pfam PF03625 Domain of unknown function DUF302 34 96 5.6E-17 T 15-10-2018 IPR005180 Domain of unknown function DUF302 C2I28_25250 7c768e1ca5b16b8ef8866a71c743e094 127 PIRSF PIRSF021774 1 127 4.3E-41 T 15-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 C2I28_25250 7c768e1ca5b16b8ef8866a71c743e094 127 Gene3D G3DSA:3.30.310.70 1 126 3.9E-48 T 15-10-2018 IPR035923 TT1751-like domain superfamily C2I28_01735 6155dd4784e4efd4352e36a64902039a 71 Gene3D G3DSA:1.10.150.260 1 71 2.5E-29 T 15-10-2018 IPR036806 YozE SAM-like superfamily C2I28_01735 6155dd4784e4efd4352e36a64902039a 71 SUPERFAMILY SSF140652 1 70 6.28E-29 T 15-10-2018 IPR036806 YozE SAM-like superfamily C2I28_01735 6155dd4784e4efd4352e36a64902039a 71 Hamap MF_01538 UPF0346 protein . 1 70 21.89 T 15-10-2018 IPR010673 Protein of unknown function UPF0346 C2I28_01735 6155dd4784e4efd4352e36a64902039a 71 Pfam PF06855 YozE SAM-like fold 3 69 3.7E-29 T 15-10-2018 IPR023089 YozE SAM-like domain C2I28_01735 6155dd4784e4efd4352e36a64902039a 71 PIRSF PIRSF037262 1 71 1.8E-32 T 15-10-2018 IPR010673 Protein of unknown function UPF0346 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 Pfam PF00072 Response regulator receiver domain 7 115 2.3E-21 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 Pfam PF04397 LytTr DNA-binding domain 146 241 3.8E-19 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 SMART SM00448 4 115 6.9E-20 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 Gene3D G3DSA:3.40.50.2300 1 133 1.7E-30 T 15-10-2018 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 SMART SM00850 145 242 2.5E-22 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 Gene3D G3DSA:2.40.50.1020 134 237 4.3E-17 T 15-10-2018 C2I28_14175 b67bad162382f9bc8ebd0f6715045db7 247 SUPERFAMILY SSF52172 1 120 1.42E-28 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 SUPERFAMILY SSF53955 41 248 2.05E-73 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 Pfam PF00912 Transglycosylase 54 227 9.4E-66 T 15-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 63 592 5.2E-180 T 15-10-2018 C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 Gene3D G3DSA:1.10.3810.10 62 252 1.5E-189 T 15-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 Gene3D G3DSA:3.40.710.10 292 603 1.5E-189 T 15-10-2018 C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 SUPERFAMILY SSF56601 208 608 1.43E-100 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 Pfam PF00905 Penicillin binding protein transpeptidase domain 318 590 4.3E-41 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_11150 75f9ad0b9029e729416db903a50d7eab 709 Gene3D G3DSA:3.90.1310.20 48 500 1.5E-189 T 15-10-2018 C2I28_02785 17e1598b9881fba9f8dace7686dacd3e 73 SUPERFAMILY SSF63562 1 67 2.09E-21 T 15-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I28_02785 17e1598b9881fba9f8dace7686dacd3e 73 SMART SM01409 8 61 5.6E-14 T 15-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I28_02785 17e1598b9881fba9f8dace7686dacd3e 73 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 14.976 T 15-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_02785 17e1598b9881fba9f8dace7686dacd3e 73 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.7E-20 T 15-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_02785 17e1598b9881fba9f8dace7686dacd3e 73 Gene3D G3DSA:3.90.940.10 1 73 2.2E-18 T 15-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I28_02785 17e1598b9881fba9f8dace7686dacd3e 73 Pfam PF01192 RNA polymerase Rpb6 9 60 1.3E-12 T 15-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 Gene3D G3DSA:1.10.10.10 97 161 5.2E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 SUPERFAMILY SSF88946 12 92 1.1E-16 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 Pfam PF08281 Sigma-70, region 4 105 153 2.0E-14 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 Gene3D G3DSA:1.10.1740.10 2 81 8.0E-18 T 15-10-2018 C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 156 3.2E-24 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 SUPERFAMILY SSF88659 98 159 1.87E-15 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 35 66 - T 15-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_01035 d063ae69ff2f2a33f8a385004fd76284 166 Pfam PF04542 Sigma-70 region 2 14 80 2.2E-12 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_22930 a022d47edde49f427c2d96e8b6ad04ee 269 Hamap MF_01384 Urease accessory protein UreD [ureD]. 3 255 25.626 T 15-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 C2I28_22930 a022d47edde49f427c2d96e8b6ad04ee 269 Pfam PF01774 UreD urease accessory protein 44 244 6.2E-47 T 15-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 536 552 - T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 Gene3D G3DSA:3.40.930.10 490 630 1.4E-43 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 Pfam PF02378 Phosphotransferase system, EIIC 19 278 5.0E-17 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 380 464 5.7E-12 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 492 629 1.8E-34 T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 10 345 3.5E-166 T 15-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 SUPERFAMILY SSF55804 492 628 4.19E-39 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 SUPERFAMILY SSF52794 378 467 6.15E-26 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_09015 0ab1828250ab59b23adb1337c656c8a4 630 Gene3D G3DSA:3.40.50.2300 369 470 5.4E-38 T 15-10-2018 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 SMART SM00357 3 66 5.0E-33 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 PIRSF PIRSF002599 1 66 1.5E-25 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 PRINTS PR00050 Cold shock protein signature 4 19 1.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 PRINTS PR00050 Cold shock protein signature 24 33 1.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 PRINTS PR00050 Cold shock protein signature 39 57 1.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 SUPERFAMILY SSF50249 1 64 2.67E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.6E-32 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_21650 8479f6ed89ea5a955d953d6e95833883 66 Gene3D G3DSA:2.40.50.140 1 66 2.9E-31 T 15-10-2018 C2I28_15060 72683b48fdfeb75b9299bb4f2a96217b 199 TIGRFAM TIGR00648 recU: recombination protein U 29 197 6.3E-77 T 15-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I28_15060 72683b48fdfeb75b9299bb4f2a96217b 199 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 199 99.238 T 15-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I28_15060 72683b48fdfeb75b9299bb4f2a96217b 199 SUPERFAMILY SSF52980 32 198 5.9E-68 T 15-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I28_15060 72683b48fdfeb75b9299bb4f2a96217b 199 Gene3D G3DSA:3.40.1350.10 33 199 2.4E-67 T 15-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 C2I28_15060 72683b48fdfeb75b9299bb4f2a96217b 199 Pfam PF03838 Recombination protein U 30 195 7.2E-66 T 15-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I28_15060 72683b48fdfeb75b9299bb4f2a96217b 199 PIRSF PIRSF037785 22 199 4.1E-78 T 15-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 C2I28_18920 2166af4f7bd152b399bbd9ebe2f7dfae 396 Pfam PF00534 Glycosyl transferases group 1 223 377 1.2E-29 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_18920 2166af4f7bd152b399bbd9ebe2f7dfae 396 Gene3D G3DSA:3.40.50.2000 205 379 3.2E-41 T 15-10-2018 C2I28_18920 2166af4f7bd152b399bbd9ebe2f7dfae 396 Gene3D G3DSA:3.40.50.2000 148 204 3.2E-41 T 15-10-2018 C2I28_18920 2166af4f7bd152b399bbd9ebe2f7dfae 396 SUPERFAMILY SSF53756 5 377 1.7E-49 T 15-10-2018 C2I28_17315 153d28ed01fb6cec0aee3b69721f9a35 98 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 12 84 3.8E-14 T 15-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 C2I28_17315 153d28ed01fb6cec0aee3b69721f9a35 98 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 4 92 2.7E-25 T 15-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 SUPERFAMILY SSF55174 1 90 1.67E-13 T 15-10-2018 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 Gene3D G3DSA:3.30.70.580 62 230 1.1E-56 T 15-10-2018 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 15-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 SMART SM00363 1 59 1.0E-7 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 Pfam PF01479 S4 domain 1 45 1.4E-9 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 Pfam PF00849 RNA pseudouridylate synthase 62 195 1.1E-19 T 15-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 1.5E-46 T 15-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 Gene3D G3DSA:3.30.70.1560 129 212 1.1E-56 T 15-10-2018 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 SUPERFAMILY SSF55120 61 230 6.84E-42 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_05770 ea6f3be78dafafeb4e9780b2e855443c 238 Gene3D G3DSA:3.10.290.10 1 57 1.3E-16 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SUPERFAMILY SSF48452 531 740 1.52E-13 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Gene3D G3DSA:1.25.40.10 888 1034 3.3E-27 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Pfam PF13424 Tetratricopeptide repeat 751 822 1.7E-10 T 15-10-2018 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Pfam PF13424 Tetratricopeptide repeat 671 741 2.7E-7 T 15-10-2018 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 585 618 0.42 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 963 996 43.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 751 784 25.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 532 565 4.5 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 712 742 130.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 671 704 100.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 629 662 3.1 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SMART SM00028 921 954 0.0025 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Gene3D G3DSA:1.25.40.10 518 706 2.1E-21 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SUPERFAMILY SSF48452 727 1020 1.14E-14 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Pfam PF13374 Tetratricopeptide repeat 921 959 0.018 T 15-10-2018 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Pfam PF13374 Tetratricopeptide repeat 963 1002 4.3E-4 T 15-10-2018 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 SUPERFAMILY SSF52540 27 350 2.68E-13 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Gene3D G3DSA:1.25.40.10 707 802 2.6E-15 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26935 79a2e51a4200c3eac93e842674a73f18 1036 Gene3D G3DSA:1.25.40.10 803 887 6.7E-7 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 Gene3D G3DSA:1.10.260.40 1 65 2.6E-21 T 15-10-2018 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 SUPERFAMILY SSF47413 6 63 1.03E-15 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 Pfam PF13377 Periplasmic binding protein-like domain 176 332 2.2E-35 T 15-10-2018 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 SMART SM00354 5 78 8.0E-27 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 17 27 6.5E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 7 17 6.5E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 Gene3D G3DSA:3.40.50.2300 66 155 1.1E-14 T 15-10-2018 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 SUPERFAMILY SSF53822 68 333 2.86E-56 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 Gene3D G3DSA:3.40.50.2300 162 335 3.9E-42 T 15-10-2018 C2I28_07745 4d0410df9f814cc65a8b3b1f9a4188b5 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 55 2.1E-16 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_24730 f888209da652580f0195cf43cfea4df0 183 Gene3D G3DSA:1.10.1660.10 1 111 2.4E-7 T 15-10-2018 C2I28_24730 f888209da652580f0195cf43cfea4df0 183 SUPERFAMILY SSF46955 5 80 2.93E-8 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_24730 f888209da652580f0195cf43cfea4df0 183 Pfam PF13411 MerR HTH family regulatory protein 6 73 2.0E-8 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 Pfam PF00162 Phosphoglycerate kinase 6 383 1.4E-167 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 SUPERFAMILY SSF53748 1 393 2.12E-166 T 15-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 6.8E-100 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 PIRSF PIRSF000724 1 394 9.4E-160 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 Gene3D G3DSA:3.40.50.1260 7 391 2.1E-167 T 15-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 15-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.094 T 15-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06825 fbc4b53f9b34ef25eab3388de7020882 394 Gene3D G3DSA:3.40.50.1260 169 383 2.1E-167 T 15-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 SMART SM00878 336 442 1.2E-69 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 1.6E-80 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 SUPERFAMILY SSF52440 1 113 4.68E-50 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 Gene3D G3DSA:3.30.470.130 1 450 2.4E-202 T 15-10-2018 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.0E-47 T 15-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 SUPERFAMILY SSF56059 83 349 1.11E-70 T 15-10-2018 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 SUPERFAMILY SSF51246 331 444 2.04E-47 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 9.5E-44 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_20425 a3c61b015eaac145b9f37a671febd782 454 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 5.8E-234 T 15-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 C2I28_09620 22daf303191b20618e2bd97d9351a64d 173 SUPERFAMILY SSF55166 38 165 5.49E-32 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_09620 22daf303191b20618e2bd97d9351a64d 173 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 94 163 7.1E-21 T 15-10-2018 IPR039561 Peptidase M15C GO:0008233 C2I28_09620 22daf303191b20618e2bd97d9351a64d 173 Gene3D G3DSA:3.30.1380.10 34 163 4.0E-42 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 861 0.0 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 878 5.1E-24 T 15-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Gene3D G3DSA:1.10.730.10 8 742 0.0 T 15-10-2018 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Gene3D G3DSA:1.10.287.380 807 879 2.2E-24 T 15-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 SUPERFAMILY SSF50677 197 347 5.62E-65 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 5.2E-40 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 5.2E-40 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 5.2E-40 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 5.2E-40 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 5.2E-40 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 SUPERFAMILY SSF52374 6 575 6.31E-146 T 15-10-2018 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 SUPERFAMILY SSF46589 814 878 9.94E-17 T 15-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 SUPERFAMILY SSF47323 577 829 4.86E-77 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Gene3D G3DSA:3.90.740.10 181 347 0.0 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Pfam PF08264 Anticodon-binding domain of tRNA 608 755 7.1E-45 T 15-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 565 1.5E-226 T 15-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Gene3D G3DSA:3.40.50.620 28 526 0.0 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_04935 69d3f9e9b6ee8f459d0690823a992eed 880 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 879 16.275 T 15-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 C2I28_15630 0a5a152bc7bac82cb29ab30bab82702d 335 SUPERFAMILY SSF81345 6 334 3.4E-74 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_15630 0a5a152bc7bac82cb29ab30bab82702d 335 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 5.7E-5 T 15-10-2018 C2I28_15630 0a5a152bc7bac82cb29ab30bab82702d 335 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 5.7E-5 T 15-10-2018 C2I28_15630 0a5a152bc7bac82cb29ab30bab82702d 335 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 5.7E-5 T 15-10-2018 C2I28_15630 0a5a152bc7bac82cb29ab30bab82702d 335 Pfam PF01032 FecCD transport family 21 334 4.2E-84 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_15630 0a5a152bc7bac82cb29ab30bab82702d 335 Gene3D G3DSA:1.10.3470.10 7 335 1.6E-88 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 SMART SM00347 36 136 1.2E-19 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 Pfam PF01047 MarR family 43 101 4.7E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 SUPERFAMILY SSF46785 38 151 1.6E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 1.6E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 1.6E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 1.6E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 1.6E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20275 246ce1ee1e37302f36ccb2e4b8166b47 152 Gene3D G3DSA:1.10.10.10 17 152 2.8E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 SMART SM00357 3 66 1.3E-30 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 Gene3D G3DSA:2.40.50.140 1 65 3.4E-30 T 15-10-2018 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 PIRSF PIRSF002599 1 66 2.4E-24 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.0E-30 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 PRINTS PR00050 Cold shock protein signature 4 19 7.7E-20 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 PRINTS PR00050 Cold shock protein signature 24 33 7.7E-20 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 PRINTS PR00050 Cold shock protein signature 39 57 7.7E-20 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_00705 16153a81ac1308646ece216820b5e7d9 66 SUPERFAMILY SSF50249 1 64 3.11E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_17880 76f7f59e90d0f2c7d8b028e6cc7664b0 132 Pfam PF04134 Protein of unknown function, DUF393 5 114 1.1E-34 T 15-10-2018 IPR007263 Protein of unknown function DUF393 C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 SUPERFAMILY SSF46689 2 67 1.3E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 48 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 6.3E-9 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 6.3E-9 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 Gene3D G3DSA:1.10.357.10 46 187 1.6E-32 T 15-10-2018 C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 Gene3D G3DSA:1.10.10.60 1 45 1.3E-18 T 15-10-2018 C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 SUPERFAMILY SSF48498 75 185 2.37E-21 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_19840 48d320f7462749d768b77e5acad7a2c6 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 48 2.0E-15 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_12115 a886e48b0ce49a4bfb4dd455349b8dba 237 SUPERFAMILY SSF117856 8 237 3.24E-78 T 15-10-2018 C2I28_12115 a886e48b0ce49a4bfb4dd455349b8dba 237 Gene3D G3DSA:3.30.1330.80 9 224 4.0E-82 T 15-10-2018 C2I28_12115 a886e48b0ce49a4bfb4dd455349b8dba 237 PIRSF PIRSF001332 1 237 1.6E-91 T 15-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 C2I28_12115 a886e48b0ce49a4bfb4dd455349b8dba 237 Gene3D G3DSA:3.30.1330.80 83 205 4.0E-82 T 15-10-2018 C2I28_12115 a886e48b0ce49a4bfb4dd455349b8dba 237 Pfam PF03306 Alpha-acetolactate decarboxylase 9 225 1.1E-82 T 15-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 C2I28_12115 a886e48b0ce49a4bfb4dd455349b8dba 237 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 9 237 8.9E-88 T 15-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 Pfam PF07687 Peptidase dimerisation domain 191 278 4.7E-17 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 Pfam PF01546 Peptidase family M20/M25/M40 92 385 1.2E-27 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 SUPERFAMILY SSF55031 194 302 1.03E-21 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 SUPERFAMILY SSF53187 12 386 2.88E-46 T 15-10-2018 C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 Gene3D G3DSA:3.40.630.10 35 376 8.8E-111 T 15-10-2018 C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 Gene3D G3DSA:3.30.70.360 194 301 8.8E-111 T 15-10-2018 C2I28_09715 6cc244e20f750d7655dbd51e269a5b12 387 PIRSF PIRSF037238 14 387 7.4E-126 T 15-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase C2I28_15690 6fa70bb5b4dd043a093309442192c13d 213 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 9.3E-30 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_15690 6fa70bb5b4dd043a093309442192c13d 213 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 206 1.0E-84 T 15-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 C2I28_15690 6fa70bb5b4dd043a093309442192c13d 213 SMART SM00934 2 203 6.1E-39 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_15690 6fa70bb5b4dd043a093309442192c13d 213 SUPERFAMILY SSF51366 3 209 4.16E-41 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_15690 6fa70bb5b4dd043a093309442192c13d 213 Gene3D G3DSA:3.20.20.70 1 211 2.1E-75 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 Gene3D G3DSA:3.40.50.300 1 152 4.8E-33 T 15-10-2018 C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 2 1164 0.0 T 15-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1164 62.383 T 15-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 Gene3D G3DSA:3.40.50.300 277 435 3.0E-34 T 15-10-2018 C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 Gene3D G3DSA:3.40.50.300 530 699 6.0E-46 T 15-10-2018 C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 SUPERFAMILY SSF52540 304 750 5.75E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11360 540b05dd1c586093eab98b2d728fa4d3 1166 Pfam PF12705 PD-(D/E)XK nuclease superfamily 790 1133 3.2E-61 T 15-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 177 182 - T 15-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 Pfam PF04002 RadC-like JAB domain 108 226 2.2E-47 T 15-10-2018 IPR025657 RadC-like JAB domain C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 Gene3D G3DSA:3.40.140.10 104 228 1.8E-47 T 15-10-2018 C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 TIGRFAM TIGR00608 radc: DNA repair protein RadC 15 228 2.2E-84 T 15-10-2018 IPR001405 Uncharacterised protein family UPF0758 C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 Gene3D G3DSA:1.10.150.20 51 91 2.8E-6 T 15-10-2018 C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 SUPERFAMILY SSF102712 157 205 7.45E-6 T 15-10-2018 C2I28_04900 86306927039bceae539c25fd0be4bcf5 228 SUPERFAMILY SSF47781 19 93 2.92E-9 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_04455 5ad4a779be916ac0b4bbe08258a84c9a 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 6.0E-38 T 15-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS C2I28_04455 5ad4a779be916ac0b4bbe08258a84c9a 117 Gene3D G3DSA:3.30.460.10 1 108 8.8E-41 T 15-10-2018 C2I28_04455 5ad4a779be916ac0b4bbe08258a84c9a 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 25.895 T 15-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS C2I28_04455 5ad4a779be916ac0b4bbe08258a84c9a 117 SUPERFAMILY SSF81301 1 113 5.07E-42 T 15-10-2018 C2I28_04455 5ad4a779be916ac0b4bbe08258a84c9a 117 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 7.2E-28 T 15-10-2018 C2I28_05075 9d32244602ec793419f4a2d006949a27 361 SMART SM00909 252 341 1.8E-21 T 15-10-2018 IPR019606 GerMN domain C2I28_05075 9d32244602ec793419f4a2d006949a27 361 SMART SM00909 100 191 1.7E-22 T 15-10-2018 IPR019606 GerMN domain C2I28_05075 9d32244602ec793419f4a2d006949a27 361 Pfam PF10646 Sporulation and spore germination 224 336 7.0E-15 T 15-10-2018 IPR019606 GerMN domain C2I28_05075 9d32244602ec793419f4a2d006949a27 361 Pfam PF10646 Sporulation and spore germination 77 185 6.3E-18 T 15-10-2018 IPR019606 GerMN domain C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 362 408 3.1E-9 T 15-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 Pfam PF00753 Metallo-beta-lactamase superfamily 18 173 2.1E-9 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 Gene3D G3DSA:3.40.50.10710 208 365 1.9E-158 T 15-10-2018 C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 42.825 T 15-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 Gene3D G3DSA:3.60.15.10 10 435 1.9E-158 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 Gene3D G3DSA:3.10.20.580 449 555 5.2E-39 T 15-10-2018 C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 1.3E-187 T 15-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 SMART SM00849 21 216 2.9E-21 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 PIRSF PIRSF004803 1 555 6.9E-209 T 15-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I28_02245 1583b5916073c993c6db9ec7a1f789da 555 SUPERFAMILY SSF56281 9 424 3.17E-80 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 Gene3D G3DSA:1.10.357.10 69 205 5.4E-10 T 15-10-2018 C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 Gene3D G3DSA:1.10.10.60 4 68 1.8E-17 T 15-10-2018 C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 SUPERFAMILY SSF46689 15 95 2.19E-18 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 SUPERFAMILY SSF48498 99 205 6.12E-6 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.1E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.1E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 69 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_16440 8d5effac1710fc834b103bc810be93f6 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 2.7E-15 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 451 3.0E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 SMART SM00387 344 454 2.0E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:1.10.287.130 243 299 1.8E-33 T 15-10-2018 C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 SUPERFAMILY SSF55874 296 453 2.23E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_26325 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:3.30.565.10 300 451 1.8E-33 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 451 3.0E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 SMART SM00387 344 454 2.0E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:1.10.287.130 243 299 1.8E-33 T 15-10-2018 C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 SUPERFAMILY SSF55874 296 453 2.23E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_26225 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:3.30.565.10 300 451 1.8E-33 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 451 3.0E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 SMART SM00387 344 454 2.0E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:1.10.287.130 243 299 1.8E-33 T 15-10-2018 C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 SUPERFAMILY SSF55874 296 453 2.23E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_27175 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:3.30.565.10 300 451 1.8E-33 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 451 3.0E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 SMART SM00387 344 454 2.0E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 8.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:1.10.287.130 243 299 1.8E-33 T 15-10-2018 C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 SUPERFAMILY SSF55874 296 453 2.23E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_27075 e49d8175c5e5554b6163d53fa1ba898b 469 Gene3D G3DSA:3.30.565.10 300 451 1.8E-33 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 774 7.4E-257 T 15-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 555 614 1.8E-10 T 15-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PIRSF PIRSF037149 1 778 1.3E-262 T 15-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Pfam PF04324 BFD-like [2Fe-2S] binding domain 414 462 1.6E-14 T 15-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 281 3.7E-58 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Gene3D G3DSA:3.90.480.10 554 606 1.1E-5 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 SUPERFAMILY SSF51905 1 305 6.02E-42 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 SUPERFAMILY SSF56014 634 758 8.51E-19 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 644 756 5.0E-10 T 15-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Gene3D G3DSA:3.30.390.30 316 396 2.2E-11 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Gene3D G3DSA:3.50.50.60 7 287 6.9E-88 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 SUPERFAMILY SSF55124 505 615 1.13E-15 T 15-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-21 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.3E-21 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.3E-21 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.3E-21 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.3E-21 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 4.4E-12 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.4E-12 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 4.4E-12 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 4.4E-12 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Gene3D G3DSA:3.50.50.60 115 239 6.9E-88 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Gene3D G3DSA:1.10.10.1100 414 467 9.0E-9 T 15-10-2018 C2I28_12100 3665e3539289f398d38d9a919adf6c22 781 Gene3D G3DSA:3.30.413.10 624 778 3.1E-16 T 15-10-2018 C2I28_14380 f6f11e143c23b209442f1118c6ac1155 460 Pfam PF03553 Na+/H+ antiporter family 157 451 1.1E-57 T 15-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I28_14380 f6f11e143c23b209442f1118c6ac1155 460 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 8 457 3.2E-147 T 15-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 PIRSF PIRSF039102 1 355 2.0E-113 T 15-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 SUPERFAMILY SSF52440 2 134 3.07E-35 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 Gene3D G3DSA:3.30.1490.20 150 220 2.6E-27 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 289 317 - T 15-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 Pfam PF01820 D-ala D-ala ligase N-terminus 4 124 1.3E-30 T 15-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 347 41.116 T 15-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 SUPERFAMILY SSF56059 135 352 1.77E-61 T 15-10-2018 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 15-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 Gene3D G3DSA:3.30.470.20 221 360 7.0E-50 T 15-10-2018 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 346 3.2E-115 T 15-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 Pfam PF07478 D-ala D-ala ligase C-terminus 142 343 3.6E-77 T 15-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09105 aa15b811a1df3bc4a28f8d9b10633054 360 Gene3D G3DSA:3.40.50.20 1 124 6.0E-36 T 15-10-2018 C2I28_08420 6a9e25cb07b39d95711ffec1b4fc4361 155 SUPERFAMILY SSF50249 4 85 8.26E-26 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_08420 6a9e25cb07b39d95711ffec1b4fc4361 155 Pfam PF00575 S1 RNA binding domain 4 74 1.7E-22 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_08420 6a9e25cb07b39d95711ffec1b4fc4361 155 SMART SM00316 4 74 1.1E-27 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_08420 6a9e25cb07b39d95711ffec1b4fc4361 155 Gene3D G3DSA:2.40.50.140 1 84 3.5E-29 T 15-10-2018 C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 Gene3D G3DSA:3.90.1150.10 6 395 4.3E-185 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 PIRSF PIRSF005572 20 404 1.5E-52 T 15-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 6.7E-192 T 15-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 Gene3D G3DSA:3.40.640.10 34 294 4.3E-185 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 SUPERFAMILY SSF53383 2 398 3.29E-134 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 Pfam PF00266 Aminotransferase class-V 23 391 1.7E-164 T 15-10-2018 IPR000192 Aminotransferase class V domain C2I28_06525 b316cb0cbd9b1f3c4dace4111aac5be4 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 15-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site C2I28_04090 5d183a48e1d99eade3c4f752def02ab1 49 SUPERFAMILY SSF57829 1 49 6.71E-19 T 15-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I28_04090 5d183a48e1d99eade3c4f752def02ab1 49 Gene3D G3DSA:2.20.28.120 1 49 3.2E-24 T 15-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04090 5d183a48e1d99eade3c4f752def02ab1 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 15-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04090 5d183a48e1d99eade3c4f752def02ab1 49 Pfam PF00471 Ribosomal protein L33 3 49 3.9E-23 T 15-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04090 5d183a48e1d99eade3c4f752def02ab1 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.14 T 15-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04090 5d183a48e1d99eade3c4f752def02ab1 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 3.6E-20 T 15-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_27635 6cdec0e296dab077755bfd70bb728f0e 203 Gene3D G3DSA:3.40.50.1390 4 133 4.8E-33 T 15-10-2018 C2I28_27635 6cdec0e296dab077755bfd70bb728f0e 203 SUPERFAMILY SSF53041 4 149 1.83E-33 T 15-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 C2I28_27635 6cdec0e296dab077755bfd70bb728f0e 203 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 15-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 C2I28_27635 6cdec0e296dab077755bfd70bb728f0e 203 SMART SM00857 5 150 2.7E-30 T 15-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I28_27635 6cdec0e296dab077755bfd70bb728f0e 203 Pfam PF00239 Resolvase, N terminal domain 6 148 2.6E-25 T 15-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 C2I28_20985 036bbdabada1e57be00dd6ca2e2b30f6 157 SUPERFAMILY SSF49764 32 146 1.78E-19 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_20985 036bbdabada1e57be00dd6ca2e2b30f6 157 Pfam PF00011 Hsp20/alpha crystallin family 61 150 7.4E-12 T 15-10-2018 IPR002068 Alpha crystallin/Hsp20 domain C2I28_20985 036bbdabada1e57be00dd6ca2e2b30f6 157 Gene3D G3DSA:2.60.40.790 25 157 3.4E-21 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 PIRSF PIRSF006294 2 528 1.8E-239 T 15-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 SUPERFAMILY SSF68923 5 212 2.62E-75 T 15-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 Gene3D G3DSA:3.40.449.10 28 214 1.8E-225 T 15-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 529 54.95 T 15-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 Gene3D G3DSA:3.90.228.20 215 514 1.8E-225 T 15-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 SUPERFAMILY SSF53795 214 518 6.87E-135 T 15-10-2018 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 Gene3D G3DSA:2.170.8.10 38 331 1.8E-225 T 15-10-2018 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 4 529 9.8E-246 T 15-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I28_05860 b8e86562a34287fba22f8c2e5a41ba57 529 Pfam PF01293 Phosphoenolpyruvate carboxykinase 19 482 1.4E-224 T 15-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 C2I28_01360 2b43007200c49efbbce98a2f21b40ebd 164 SUPERFAMILY SSF55729 11 152 9.41E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01360 2b43007200c49efbbce98a2f21b40ebd 164 Pfam PF00583 Acetyltransferase (GNAT) family 43 140 8.7E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_01360 2b43007200c49efbbce98a2f21b40ebd 164 Gene3D G3DSA:3.40.630.30 4 164 1.1E-21 T 15-10-2018 C2I28_03950 87534a279ffa7fe7a8771cae203a1ef7 293 SUPERFAMILY SSF52151 6 288 1.83E-44 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_03950 87534a279ffa7fe7a8771cae203a1ef7 293 Gene3D G3DSA:3.40.1090.20 2 85 2.0E-21 T 15-10-2018 C2I28_03950 87534a279ffa7fe7a8771cae203a1ef7 293 Gene3D G3DSA:3.40.1090.10 111 291 2.3E-20 T 15-10-2018 C2I28_03950 87534a279ffa7fe7a8771cae203a1ef7 293 Pfam PF01734 Patatin-like phospholipase 6 194 1.4E-34 T 15-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I28_26830 d0f09e768688751775d4852ac7929622 141 Gene3D G3DSA:3.10.180.10 9 141 7.7E-45 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_26830 d0f09e768688751775d4852ac7929622 141 SUPERFAMILY SSF54593 2 137 5.49E-35 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_26830 d0f09e768688751775d4852ac7929622 141 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 135 1.8E-9 T 15-10-2018 IPR028973 PhnB-like C2I28_11680 a3c9a62c67280467fe5a4cfd7cf1e77b 304 Gene3D G3DSA:1.10.3720.10 90 299 1.1E-21 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11680 a3c9a62c67280467fe5a4cfd7cf1e77b 304 SUPERFAMILY SSF161098 94 284 3.92E-24 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11680 a3c9a62c67280467fe5a4cfd7cf1e77b 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 74 1.0E-12 T 15-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I28_11680 a3c9a62c67280467fe5a4cfd7cf1e77b 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 301 1.6E-30 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 Gene3D G3DSA:3.40.47.10 1 254 1.7E-106 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 1.2E-40 T 15-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 PIRSF PIRSF000447 1 413 8.5E-190 T 15-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 7.3E-61 T 15-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 Gene3D G3DSA:3.40.47.10 256 400 3.1E-57 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 SUPERFAMILY SSF53901 4 251 2.54E-76 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 15-10-2018 IPR018201 Beta-ketoacyl synthase, active site C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 SUPERFAMILY SSF53901 214 411 2.64E-77 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 SMART SM00825 Beta-ketoacyl synthase 6 413 5.1E-18 T 15-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain C2I28_11650 702572746f6b1b2f88789da8ef35c7af 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 1.3E-201 T 15-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 PRINTS PR00046 Major sigma-70 factor signature 192 200 3.2E-32 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 PRINTS PR00046 Major sigma-70 factor signature 316 328 3.2E-32 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 PRINTS PR00046 Major sigma-70 factor signature 352 363 3.2E-32 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 PRINTS PR00046 Major sigma-70 factor signature 168 181 3.2E-32 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 PRINTS PR00046 Major sigma-70 factor signature 337 352 3.2E-32 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 10 377 34.311 T 15-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 337 363 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Pfam PF03979 Sigma-70 factor, region 1.1 17 90 3.6E-16 T 15-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Pfam PF04539 Sigma-70 region 3 223 299 6.6E-33 T 15-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Pfam PF00140 Sigma-70 factor, region 1.2 106 139 2.9E-18 T 15-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 168 181 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 SUPERFAMILY SSF88659 274 375 3.36E-30 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Pfam PF04542 Sigma-70 region 2 144 213 4.0E-22 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 140 376 2.6E-125 T 15-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Gene3D G3DSA:1.10.10.10 217 292 8.7E-36 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Gene3D G3DSA:1.10.10.10 305 377 2.8E-36 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Gene3D G3DSA:1.10.220.120 16 76 2.3E-9 T 15-10-2018 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 SUPERFAMILY SSF88659 217 290 2.8E-23 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Pfam PF04545 Sigma-70, region 4 312 365 5.2E-20 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Gene3D G3DSA:1.10.601.10 139 216 4.8E-51 T 15-10-2018 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 Gene3D G3DSA:1.10.601.10 104 138 2.5E-12 T 15-10-2018 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 140 365 8.5E-40 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_04260 b2e3574a40d653058d0291ba4e3794b2 377 SUPERFAMILY SSF88946 105 214 6.41E-55 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.5E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.5E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.5E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 Gene3D G3DSA:3.40.50.720 1 257 1.2E-84 T 15-10-2018 C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 7.1E-72 T 15-10-2018 C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 SUPERFAMILY SSF51735 5 253 1.35E-86 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.2E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_06660 0ff9170fa80aa4c8ac88ee1c6ccfad1e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_20580 e036b5e3fc9d51bb666bc8fe0045626e 477 Pfam PF00501 AMP-binding enzyme 10 375 1.2E-60 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_20580 e036b5e3fc9d51bb666bc8fe0045626e 477 Gene3D G3DSA:3.30.300.30 370 473 7.0E-22 T 15-10-2018 C2I28_20580 e036b5e3fc9d51bb666bc8fe0045626e 477 Gene3D G3DSA:3.40.50.12780 1 368 9.3E-67 T 15-10-2018 C2I28_20580 e036b5e3fc9d51bb666bc8fe0045626e 477 Pfam PF13193 AMP-binding enzyme C-terminal domain 384 456 2.0E-10 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_20580 e036b5e3fc9d51bb666bc8fe0045626e 477 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_20580 e036b5e3fc9d51bb666bc8fe0045626e 477 SUPERFAMILY SSF56801 4 472 1.44E-98 T 15-10-2018 C2I28_13020 3eb189d657c5e639ce078bbbf6aa752f 582 SUPERFAMILY SSF75304 11 445 4.32E-91 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_13020 3eb189d657c5e639ce078bbbf6aa752f 582 Pfam PF01425 Amidase 28 430 1.5E-66 T 15-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_13020 3eb189d657c5e639ce078bbbf6aa752f 582 Gene3D G3DSA:3.10.490.10 454 582 3.1E-45 T 15-10-2018 C2I28_13020 3eb189d657c5e639ce078bbbf6aa752f 582 Gene3D G3DSA:1.20.58.1700 295 370 7.4E-122 T 15-10-2018 C2I28_13020 3eb189d657c5e639ce078bbbf6aa752f 582 Gene3D G3DSA:3.90.1300.10 44 437 7.4E-122 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_13020 3eb189d657c5e639ce078bbbf6aa752f 582 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 44 579 1.9E-178 T 15-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 SUPERFAMILY SSF64158 77 310 2.09E-92 T 15-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 PIRSF PIRSF001492 1 510 3.8E-206 T 15-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.028 T 15-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 Pfam PF01676 Metalloenzyme superfamily 4 497 7.1E-78 T 15-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 Gene3D G3DSA:3.40.1450.10 77 312 1.7E-235 T 15-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 SUPERFAMILY SSF53649 3 509 1.96E-73 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 1.4E-85 T 15-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 4 509 1.8E-212 T 15-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06815 d25f1c12dcd7cfafe0daa4b51b831551 510 Gene3D G3DSA:3.40.720.10 5 509 1.7E-235 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 SMART SM00530 9 64 1.6E-13 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 Gene3D G3DSA:1.10.260.40 3 71 1.3E-17 T 15-10-2018 C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 Pfam PF07883 Cupin domain 106 174 3.8E-14 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 Gene3D G3DSA:2.60.120.10 72 176 1.0E-17 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 Pfam PF01381 Helix-turn-helix 11 61 8.3E-16 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 SUPERFAMILY SSF47413 3 70 7.32E-17 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_24715 33f81335322c745c16e8f06c4349c3ee 181 SUPERFAMILY SSF51182 57 181 1.47E-24 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_05120 89c0da1cadf5608792d29be0b4075568 184 SUPERFAMILY SSF52218 5 171 4.04E-32 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_05120 89c0da1cadf5608792d29be0b4075568 184 Pfam PF03358 NADPH-dependent FMN reductase 5 143 4.8E-32 T 15-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I28_05120 89c0da1cadf5608792d29be0b4075568 184 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 6 171 1.8E-65 T 15-10-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 C2I28_05120 89c0da1cadf5608792d29be0b4075568 184 Gene3D G3DSA:3.40.50.360 4 184 5.3E-47 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SUPERFAMILY SSF48452 126 247 2.07E-9 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF13181 Tetratricopeptide repeat 193 217 0.15 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF13181 Tetratricopeptide repeat 916 945 9.1E-7 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF13181 Tetratricopeptide repeat 568 595 0.099 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF14559 Tetratricopeptide repeat 1027 1087 3.5E-8 T 15-10-2018 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:1.25.40.10 461 660 3.7E-17 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF13529 Peptidase_C39 like family 316 421 2.6E-7 T 15-10-2018 IPR039564 Peptidase C39-like C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:1.25.40.10 1017 1091 1.8E-10 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:1.25.40.10 80 295 7.8E-10 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:1.25.40.10 1109 1390 1.8E-21 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF13432 Tetratricopeptide repeat 638 686 2.6E-7 T 15-10-2018 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Pfam PF13432 Tetratricopeptide repeat 742 798 3.4E-4 T 15-10-2018 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SUPERFAMILY SSF48452 1221 1380 3.79E-15 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:1.25.40.10 661 770 1.4E-17 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:3.90.70.10 319 456 4.6E-10 T 15-10-2018 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 Gene3D G3DSA:1.25.40.10 863 990 1.6E-14 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 599 632 88.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 667 700 160.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 1247 1280 330.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 914 946 0.035 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 1012 1046 23.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 1281 1314 1.2 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 736 769 0.49 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 633 666 20.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 190 223 12.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 565 598 0.23 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 701 735 240.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SMART SM00028 880 913 3.1 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SUPERFAMILY SSF48452 565 766 1.52E-30 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15375 a7bba62d012f31247f479c105cecd912 1401 SUPERFAMILY SSF48452 869 1083 3.26E-17 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_21480 792c701d85262d87af57524ae0187979 168 Pfam PF14434 Immunity protein Imm6 14 127 1.2E-26 T 15-10-2018 IPR025674 Immunity protein Imm6 C2I28_18130 0ed773f24622098f31d87a5bf77f1fc1 88 Gene3D G3DSA:3.40.30.10 3 84 1.3E-12 T 15-10-2018 C2I28_18130 0ed773f24622098f31d87a5bf77f1fc1 88 Pfam PF00462 Glutaredoxin 7 62 4.4E-9 T 15-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 C2I28_18130 0ed773f24622098f31d87a5bf77f1fc1 88 SUPERFAMILY SSF52833 3 83 1.33E-13 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_14955 5625a7a9a6f2eadad94ac1bf0d82bf08 288 Gene3D G3DSA:3.30.70.120 192 267 2.1E-27 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_14955 5625a7a9a6f2eadad94ac1bf0d82bf08 288 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 215 2.8E-66 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_14955 5625a7a9a6f2eadad94ac1bf0d82bf08 288 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 220 274 3.6E-23 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_14955 5625a7a9a6f2eadad94ac1bf0d82bf08 288 PIRSF PIRSF006483 2 282 2.6E-96 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 Gene3D G3DSA:3.40.50.720 1 260 3.8E-73 T 15-10-2018 C2I28_14590 688dff46510851fb7e56cd809c970b63 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 257 2.2E-56 T 15-10-2018 C2I28_14590 688dff46510851fb7e56cd809c970b63 261 SUPERFAMILY SSF51735 6 257 1.41E-77 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14590 688dff46510851fb7e56cd809c970b63 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_09320 e9b27b73c80245a4afc8943c86c6c03f 61 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 61 17.734 T 15-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I28_09320 e9b27b73c80245a4afc8943c86c6c03f 61 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 46 3.9E-20 T 15-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I28_09320 e9b27b73c80245a4afc8943c86c6c03f 61 Pfam PF02416 mttA/Hcf106 family 3 54 3.3E-22 T 15-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 SUPERFAMILY SSF103190 37 164 2.43E-30 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 SUPERFAMILY SSF55785 220 317 5.33E-8 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 1.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 502 1.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 521 1.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 482 1.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 SMART SM00387 413 522 4.7E-16 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Pfam PF13596 PAS domain 215 305 5.3E-5 T 15-10-2018 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 419 520 5.8E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Gene3D G3DSA:3.30.565.10 368 521 6.3E-30 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 SUPERFAMILY SSF55874 382 520 4.45E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 SUPERFAMILY SSF55890 316 385 1.1E-14 T 15-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Gene3D G3DSA:3.30.450.20 196 308 1.9E-21 T 15-10-2018 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 316 371 3.3E-13 T 15-10-2018 IPR039506 SpoOB, alpha-helical domain C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Pfam PF17203 Single cache domain 3 36 166 5.8E-16 T 15-10-2018 IPR033463 Single cache domain 3 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 Gene3D G3DSA:3.30.450.20 31 159 5.6E-33 T 15-10-2018 C2I28_12355 5b0cd754bc80ab285a4b39168e885ad7 522 SMART SM00091 209 274 3.4E-5 T 15-10-2018 IPR000014 PAS domain C2I28_08275 c29ff062cbfa843a24df33e812600a26 121 Pfam PF06156 Initiation control protein YabA 2 116 1.6E-39 T 15-10-2018 IPR010377 Initiation control protein YabA GO:0006260 C2I28_08275 c29ff062cbfa843a24df33e812600a26 121 Hamap MF_01159 Initiation-control protein YabA. 1 120 25.387 T 15-10-2018 IPR010377 Initiation control protein YabA GO:0006260 C2I28_08275 c29ff062cbfa843a24df33e812600a26 121 PIRSF PIRSF021439 1 121 2.7E-42 T 15-10-2018 IPR010377 Initiation control protein YabA GO:0006260 C2I28_22660 422e3feb50c17d14b605d5cc185930a6 195 Gene3D G3DSA:1.10.10.10 1 89 8.8E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22660 422e3feb50c17d14b605d5cc185930a6 195 SUPERFAMILY SSF46785 3 171 3.29E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_22660 422e3feb50c17d14b605d5cc185930a6 195 Pfam PF03551 Transcriptional regulator PadR-like family 7 82 1.7E-12 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_04270 eb8ef54fd4b70a4b5196935a598a0e95 156 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 9 153 29.469 T 15-10-2018 IPR003791 Protein of unknown function UPF0178 C2I28_04270 eb8ef54fd4b70a4b5196935a598a0e95 156 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 24 151 3.5E-39 T 15-10-2018 IPR003791 Protein of unknown function UPF0178 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 Gene3D G3DSA:1.10.246.130 252 376 1.4E-39 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 Pfam PF01019 Gamma-glutamyltranspeptidase 40 555 9.9E-145 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 381 399 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 236 252 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 451 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 140 159 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 47 72 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 460 477 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 122 140 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 266 285 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 2.0E-62 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 25 553 2.5E-166 T 15-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 Gene3D G3DSA:3.60.20.40 381 559 1.8E-61 T 15-10-2018 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 381 405 - T 15-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 C2I28_15765 10ed78a6353e27479823ac45a4b84756 562 SUPERFAMILY SSF56235 15 559 1.87E-157 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_21340 f7ee1e73c375bed197d52b870959109d 211 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 15 164 1.7E-16 T 15-10-2018 IPR014903 Protein of unknown function DUF1796 C2I28_05610 c2ad5e6188f396d854c854fdab7395a4 571 Gene3D G3DSA:3.40.50.12780 15 454 5.3E-126 T 15-10-2018 C2I28_05610 c2ad5e6188f396d854c854fdab7395a4 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_05610 c2ad5e6188f396d854c854fdab7395a4 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 548 2.8E-25 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_05610 c2ad5e6188f396d854c854fdab7395a4 571 SUPERFAMILY SSF56801 18 561 5.63E-164 T 15-10-2018 C2I28_05610 c2ad5e6188f396d854c854fdab7395a4 571 Gene3D G3DSA:3.30.300.30 457 570 6.4E-28 T 15-10-2018 C2I28_05610 c2ad5e6188f396d854c854fdab7395a4 571 Pfam PF00501 AMP-binding enzyme 52 460 2.6E-97 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_08630 67d2bb4d27cf7563fb0aba0a87124948 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 143 0.001 T 15-10-2018 C2I28_08630 67d2bb4d27cf7563fb0aba0a87124948 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.916 T 15-10-2018 IPR022973 Ribosomal protein L10 C2I28_08630 67d2bb4d27cf7563fb0aba0a87124948 166 Gene3D G3DSA:3.30.70.1730 5 133 1.5E-45 T 15-10-2018 C2I28_08630 67d2bb4d27cf7563fb0aba0a87124948 166 Pfam PF00466 Ribosomal protein L10 6 101 6.8E-31 T 15-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 C2I28_08630 67d2bb4d27cf7563fb0aba0a87124948 166 SUPERFAMILY SSF160369 5 160 7.32E-57 T 15-10-2018 C2I28_08630 67d2bb4d27cf7563fb0aba0a87124948 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 15-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 Gene3D G3DSA:1.10.287.130 229 315 1.3E-17 T 15-10-2018 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 SMART SM00388 245 313 2.3E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 469 4.1E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 SMART SM00387 358 470 8.0E-40 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 SUPERFAMILY SSF47384 234 314 1.12E-16 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 1.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 1.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 1.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 Gene3D G3DSA:3.30.565.10 319 474 5.2E-47 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 312 5.5E-15 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18080 2b633cf63223c8cc674ca038a083a7e0 475 SUPERFAMILY SSF55874 302 468 8.38E-50 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_10635 e8fe16d809e1b9cd761749bfd42da14e 288 Gene3D G3DSA:3.30.70.120 188 263 4.2E-20 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_10635 e8fe16d809e1b9cd761749bfd42da14e 288 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 7.2E-56 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_10635 e8fe16d809e1b9cd761749bfd42da14e 288 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 270 1.1E-18 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_10635 e8fe16d809e1b9cd761749bfd42da14e 288 PIRSF PIRSF006483 1 275 5.1E-74 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_22625 479cb71f27946accdbad690de484c15c 230 SMART SM00862 150 224 9.4E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_22625 479cb71f27946accdbad690de484c15c 230 Gene3D G3DSA:3.40.50.2300 2 130 5.4E-36 T 15-10-2018 C2I28_22625 479cb71f27946accdbad690de484c15c 230 SUPERFAMILY SSF46894 131 223 1.87E-26 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_22625 479cb71f27946accdbad690de484c15c 230 SUPERFAMILY SSF52172 2 124 3.42E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_22625 479cb71f27946accdbad690de484c15c 230 SMART SM00448 3 113 5.2E-42 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_22625 479cb71f27946accdbad690de484c15c 230 Pfam PF00072 Response regulator receiver domain 5 113 1.5E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_22625 479cb71f27946accdbad690de484c15c 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 223 1.5E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_22625 479cb71f27946accdbad690de484c15c 230 Gene3D G3DSA:1.10.10.10 131 229 3.5E-30 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 Pfam PF02803 Thiolase, C-terminal domain 245 361 4.3E-34 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 Gene3D G3DSA:3.40.47.10 121 359 6.7E-117 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 Pfam PF00108 Thiolase, N-terminal domain 5 233 3.7E-47 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 Gene3D G3DSA:3.40.47.10 6 246 6.7E-117 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 PIRSF PIRSF000429 2 364 6.6E-103 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 SUPERFAMILY SSF53901 4 239 4.61E-51 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 SUPERFAMILY SSF53901 242 362 3.24E-32 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_20590 163d2b490c2a1715ac641bed5604d2ff 364 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 361 1.6E-109 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_19170 945442dbb4a6ab9038fd631c7eaac047 145 Pfam PF14184 Regulatory protein YrvL 14 136 4.2E-16 T 15-10-2018 IPR025912 Regulatory protein YrvL C2I28_19170 945442dbb4a6ab9038fd631c7eaac047 145 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 11 136 4.0E-12 T 15-10-2018 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 Pfam PF04715 Anthranilate synthase component I, N terminal region 27 165 2.3E-28 T 15-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 PRINTS PR00095 Anthranilate synthase component I signature 329 342 2.0E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 PRINTS PR00095 Anthranilate synthase component I signature 343 356 2.0E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 PRINTS PR00095 Anthranilate synthase component I signature 423 437 2.0E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 PRINTS PR00095 Anthranilate synthase component I signature 438 452 2.0E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 Gene3D G3DSA:3.60.120.10 1 499 7.9E-164 T 15-10-2018 IPR005801 ADC synthase GO:0009058 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 SUPERFAMILY SSF56322 17 494 2.49E-142 T 15-10-2018 IPR005801 ADC synthase GO:0009058 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 489 3.9E-166 T 15-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_03190 95dd07010266a9bcb8ed451b8e10c20a 504 Pfam PF00425 chorismate binding enzyme 228 481 3.4E-93 T 15-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I28_07235 7791e97142d8426b266c06243601f5f4 876 Gene3D G3DSA:1.20.120.850 644 867 1.7E-85 T 15-10-2018 C2I28_07235 7791e97142d8426b266c06243601f5f4 876 Gene3D G3DSA:3.40.50.10810 409 621 4.3E-68 T 15-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily C2I28_07235 7791e97142d8426b266c06243601f5f4 876 Pfam PF12419 SNF2 Helicase protein 233 358 3.5E-34 T 15-10-2018 IPR022138 Helicase SWF/SNF-related C2I28_07235 7791e97142d8426b266c06243601f5f4 876 SMART SM00487 404 589 9.2E-31 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_07235 7791e97142d8426b266c06243601f5f4 876 Gene3D G3DSA:3.40.50.300 630 832 1.7E-85 T 15-10-2018 C2I28_07235 7791e97142d8426b266c06243601f5f4 876 SMART SM00490 735 818 1.9E-23 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_07235 7791e97142d8426b266c06243601f5f4 876 SUPERFAMILY SSF52540 390 620 1.61E-57 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07235 7791e97142d8426b266c06243601f5f4 876 Pfam PF00176 SNF2 family N-terminal domain 422 690 3.0E-61 T 15-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 C2I28_07235 7791e97142d8426b266c06243601f5f4 876 Pfam PF00271 Helicase conserved C-terminal domain 707 818 3.3E-20 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_07235 7791e97142d8426b266c06243601f5f4 876 SUPERFAMILY SSF52540 626 874 6.39E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 SMART SM00479 420 586 1.7E-54 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 SUPERFAMILY SSF50249 235 320 2.91E-11 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Pfam PF14480 DNA polymerase III polC-type N-terminus I 11 83 3.6E-21 T 15-10-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Pfam PF00929 Exonuclease 422 576 4.6E-41 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1436 453.023 T 15-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 SUPERFAMILY SSF53098 420 876 1.35E-107 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 SMART SM00481 335 402 2.8E-26 T 15-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Pfam PF11490 DNA polymerase III polC-type N-terminus II 97 205 6.5E-25 T 15-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:2.40.50.140 221 320 4.2E-31 T 15-10-2018 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 230 1436 0.0 T 15-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:1.10.150.870 1287 1422 1.4E-52 T 15-10-2018 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Pfam PF14579 Helix-hairpin-helix motif 1351 1428 3.7E-9 T 15-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:1.10.100.20 994 1041 1.6E-58 T 15-10-2018 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:3.30.420.10 413 587 3.8E-51 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 824 1245 1.8E-96 T 15-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:1.10.150.700 1229 1285 3.8E-15 T 15-10-2018 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:1.10.150.700 1095 1183 1.3E-36 T 15-10-2018 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:3.20.20.140 588 802 3.7E-59 T 15-10-2018 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Pfam PF02811 PHP domain 336 694 9.3E-52 T 15-10-2018 IPR004013 PHP domain GO:0003824 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 416 634 2.2E-62 T 15-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_02345 0a0c8e8ac89294b762ea67508939ce7e 1436 Gene3D G3DSA:3.30.1900.20 972 1094 1.6E-58 T 15-10-2018 C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 SUPERFAMILY SSF53474 401 655 2.05E-61 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 Gene3D G3DSA:3.40.50.1820 406 659 4.1E-64 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 Pfam PF00326 Prolyl oligopeptidase family 445 657 4.1E-55 T 15-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 SUPERFAMILY SSF82171 16 394 2.94E-48 T 15-10-2018 C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 Gene3D G3DSA:2.120.10.30 151 287 5.5E-18 T 15-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 Gene3D G3DSA:2.120.10.30 5 149 2.9E-30 T 15-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 Pfam PF07676 WD40-like Beta Propeller Repeat 232 271 1.1E-4 T 15-10-2018 IPR011659 WD40-like Beta Propeller C2I28_11345 7951da29881391cba0cfdd0b69dbba9f 659 Pfam PF07676 WD40-like Beta Propeller Repeat 61 95 2.1E-11 T 15-10-2018 IPR011659 WD40-like Beta Propeller C2I28_26850 9fef5051df1e1aa0ae7440ad20865b75 458 Gene3D G3DSA:3.40.640.10 78 349 1.9E-155 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_26850 9fef5051df1e1aa0ae7440ad20865b75 458 SUPERFAMILY SSF53383 13 454 8.7E-105 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_26850 9fef5051df1e1aa0ae7440ad20865b75 458 Gene3D G3DSA:3.90.1150.10 20 447 1.9E-155 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_26850 9fef5051df1e1aa0ae7440ad20865b75 458 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 286 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_26850 9fef5051df1e1aa0ae7440ad20865b75 458 Pfam PF00202 Aminotransferase class-III 42 432 1.3E-61 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_07725 f8f24aeac46f5c6cc37396f14506f3d5 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 226 2.7E-81 T 15-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I28_07725 f8f24aeac46f5c6cc37396f14506f3d5 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 1.0E-97 T 15-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I28_07725 f8f24aeac46f5c6cc37396f14506f3d5 338 PIRSF PIRSF000267 1 338 1.3E-108 T 15-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.53 T 15-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 SUPERFAMILY SSF54111 2 100 1.11E-45 T 15-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 Pfam PF00547 Urease, gamma subunit 2 99 2.0E-46 T 15-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 PIRSF PIRSF001223 1 100 4.8E-53 T 15-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 7.0E-40 T 15-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 Gene3D G3DSA:3.30.280.10 1 100 3.5E-48 T 15-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22960 3881670757ad5d3da4e6f76a2799c545 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 1.7E-49 T 15-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 SMART SM01329 4 351 7.3E-207 T 15-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 351 6.3E-142 T 15-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 243 262 - T 15-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 350 1.1E-166 T 15-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 SUPERFAMILY SSF53659 1 354 7.02E-127 T 15-10-2018 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 Gene3D G3DSA:3.40.718.10 2 369 4.4E-157 T 15-10-2018 C2I28_05030 7c055e26c297c2782c7eda8079243f7f 369 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 355 50.833 T 15-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 C2I28_18170 ae01174d9f6138a1d89946e90c3b6cbb 333 SUPERFAMILY SSF53187 1 181 5.02E-45 T 15-10-2018 C2I28_18170 ae01174d9f6138a1d89946e90c3b6cbb 333 SMART SM00646 64 176 7.6E-26 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_18170 ae01174d9f6138a1d89946e90c3b6cbb 333 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 176 4.2E-40 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_18170 ae01174d9f6138a1d89946e90c3b6cbb 333 Gene3D G3DSA:3.40.630.40 1 184 1.6E-45 T 15-10-2018 C2I28_17160 f8e8f9177f0a853c9594b77e864fad52 397 SUPERFAMILY SSF50939 31 394 3.64E-59 T 15-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 C2I28_17160 f8e8f9177f0a853c9594b77e864fad52 397 Pfam PF13088 BNR repeat-like domain 46 376 2.6E-68 T 15-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 C2I28_17160 f8e8f9177f0a853c9594b77e864fad52 397 Gene3D G3DSA:2.120.10.10 29 304 6.7E-41 T 15-10-2018 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 62 1.2E-17 T 15-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 Gene3D G3DSA:3.40.1030.10 72 316 1.2E-117 T 15-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 SUPERFAMILY SSF52418 72 331 4.71E-86 T 15-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 SUPERFAMILY SSF47648 2 67 1.96E-17 T 15-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 Gene3D G3DSA:1.20.970.10 6 183 1.2E-117 T 15-10-2018 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 332 4.6E-122 T 15-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 Pfam PF00591 Glycosyl transferase family, a/b domain 74 325 3.5E-93 T 15-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_03185 82e3cdf240766c2e5dda53c5582e3ae1 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 334 37.573 T 15-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Gene3D G3DSA:2.30.30.40 528 653 1.1E-40 T 15-10-2018 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Pfam PF01627 Hpt domain 5 97 9.0E-20 T 15-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Gene3D G3DSA:1.10.287.560 280 340 6.6E-20 T 15-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SMART SM00073 3 100 3.5E-32 T 15-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SUPERFAMILY SSF47226 2 127 1.96E-33 T 15-10-2018 IPR036641 HPT domain superfamily GO:0000160 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 281 339 1.1E-13 T 15-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SUPERFAMILY SSF55874 342 526 9.56E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Gene3D G3DSA:2.40.50.180 551 613 1.1E-40 T 15-10-2018 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SMART SM00260 520 658 2.6E-44 T 15-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SUPERFAMILY SSF47384 281 341 1.02E-14 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SUPERFAMILY SSF55052 154 236 4.97E-23 T 15-10-2018 IPR035891 CheY-binding domain of CheA C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Gene3D G3DSA:1.20.120.160 1 139 5.9E-39 T 15-10-2018 IPR036641 HPT domain superfamily GO:0000160 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 8.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 444 8.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 8.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Gene3D G3DSA:3.30.70.1110 154 238 2.8E-30 T 15-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Gene3D G3DSA:3.30.565.10 341 527 5.1E-61 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SMART SM01231 280 340 6.9E-18 T 15-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Pfam PF07194 P2 response regulator binding domain 158 235 9.0E-26 T 15-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SMART SM00387 385 528 6.4E-26 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 SUPERFAMILY SSF50341 527 658 4.19E-35 T 15-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 388 527 4.0E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_02415 1632967bcb340779b35bf5c2169b8c3a 659 Pfam PF01584 CheW-like domain 533 658 1.9E-30 T 15-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 Gene3D G3DSA:2.40.30.10 2 98 4.8E-28 T 15-10-2018 C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 SUPERFAMILY SSF63380 2 100 2.69E-23 T 15-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 255 2.5E-16 T 15-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 PIRSF PIRSF006816 1 257 6.0E-73 T 15-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 SUPERFAMILY SSF52343 95 256 9.69E-32 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 Gene3D G3DSA:3.40.50.80 102 215 1.5E-26 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 257 37.718 T 15-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit C2I28_02830 b90ee99a2d7502aaa1eb39b01574e373 257 Gene3D G3DSA:2.10.240.10 216 257 2.2E-19 T 15-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily C2I28_17025 0a790c60775baf9c797035fad9b5727a 171 Gene3D G3DSA:3.40.1580.10 3 171 3.0E-16 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_17025 0a790c60775baf9c797035fad9b5727a 171 SMART SM00860 26 164 6.1E-11 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_17025 0a790c60775baf9c797035fad9b5727a 171 SUPERFAMILY SSF160631 4 167 3.27E-19 T 15-10-2018 C2I28_17025 0a790c60775baf9c797035fad9b5727a 171 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 27 162 5.5E-25 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_03320 9392fa5847999781da2ef0a90bbebeeb 216 PIRSF PIRSF016933 1 215 2.3E-86 T 15-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 C2I28_03320 9392fa5847999781da2ef0a90bbebeeb 216 Pfam PF13367 Protease prsW family 28 199 1.1E-34 T 15-10-2018 IPR026898 Protease PrsW GO:0008233 C2I28_05005 83e026d795536075eebd651cbc269172 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 1.2E-17 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_05005 83e026d795536075eebd651cbc269172 421 Gene3D G3DSA:3.30.50.30 3 50 1.4E-21 T 15-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily C2I28_05005 83e026d795536075eebd651cbc269172 421 Gene3D G3DSA:1.10.8.60 310 417 2.4E-37 T 15-10-2018 C2I28_05005 83e026d795536075eebd651cbc269172 421 Pfam PF06689 ClpX C4-type zinc finger 12 48 5.2E-20 T 15-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 C2I28_05005 83e026d795536075eebd651cbc269172 421 SUPERFAMILY SSF57716 11 46 2.85E-11 T 15-10-2018 C2I28_05005 83e026d795536075eebd651cbc269172 421 SMART SM00994 10 49 5.4E-23 T 15-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 C2I28_05005 83e026d795536075eebd651cbc269172 421 SUPERFAMILY SSF52540 59 394 1.86E-79 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05005 83e026d795536075eebd651cbc269172 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.347 T 15-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 C2I28_05005 83e026d795536075eebd651cbc269172 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 405 1.3E-214 T 15-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 C2I28_05005 83e026d795536075eebd651cbc269172 421 SMART SM00382 108 269 3.3E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_05005 83e026d795536075eebd651cbc269172 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 304 1.9E-51 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_05005 83e026d795536075eebd651cbc269172 421 Gene3D G3DSA:3.40.50.300 53 309 7.9E-108 T 15-10-2018 C2I28_05005 83e026d795536075eebd651cbc269172 421 SMART SM01086 311 405 5.1E-33 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 SMART SM00518 3 285 1.2E-126 T 15-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 SUPERFAMILY SSF51658 2 291 9.03E-102 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 2.2E-101 T 15-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 42.627 T 15-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 Gene3D G3DSA:3.20.20.150 1 295 1.2E-102 T 15-10-2018 C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 15-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 15-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 Pfam PF01261 Xylose isomerase-like TIM barrel 21 237 2.8E-38 T 15-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I28_04220 67b3bf4e281cfcc2d0c01fab986b44fe 295 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 15-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 268 386 1.4E-7 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 266 7.2E-13 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 388 506 3.9E-11 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 27 144 9.8E-10 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 688 706 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 712 725 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 687 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 673 2.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Pfam PF13188 PAS domain 28 70 6.1E-4 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SMART SM00387 621 726 8.9E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SUPERFAMILY SSF47384 501 577 3.53E-13 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SUPERFAMILY SSF55874 572 725 1.83E-39 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Pfam PF08448 PAS fold 157 260 3.4E-8 T 15-10-2018 IPR013656 PAS fold-4 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SUPERFAMILY SSF55785 135 257 2.9E-18 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SUPERFAMILY SSF55785 376 498 6.93E-17 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Gene3D G3DSA:3.30.565.10 579 726 9.9E-46 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 624 725 1.4E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Pfam PF00512 His Kinase A (phospho-acceptor) domain 517 577 1.2E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SUPERFAMILY SSF55785 256 361 1.24E-13 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SMART SM00388 515 579 1.6E-15 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SUPERFAMILY SSF55785 31 137 2.27E-11 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Gene3D G3DSA:3.30.450.20 146 269 4.9E-19 T 15-10-2018 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Gene3D G3DSA:3.30.450.20 377 498 5.2E-18 T 15-10-2018 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Gene3D G3DSA:3.30.450.20 13 136 3.2E-12 T 15-10-2018 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SMART SM00091 391 457 1.5E-9 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SMART SM00091 271 339 1.5E-6 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SMART SM00091 28 94 0.013 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 SMART SM00091 150 216 8.3E-10 T 15-10-2018 IPR000014 PAS domain C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Gene3D G3DSA:1.10.287.130 500 578 9.1E-19 T 15-10-2018 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Gene3D G3DSA:3.30.450.20 270 376 2.2E-11 T 15-10-2018 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Pfam PF00989 PAS fold 392 460 1.8E-6 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_14265 259ba63009479dc809dc7d161ba4fa77 726 Pfam PF00989 PAS fold 272 331 3.6E-6 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_06335 6a4387f378115b0bf0cff57645c40ec6 127 Gene3D G3DSA:3.10.129.10 1 127 6.8E-51 T 15-10-2018 C2I28_06335 6a4387f378115b0bf0cff57645c40ec6 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 7 122 2.0E-37 T 15-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 C2I28_06335 6a4387f378115b0bf0cff57645c40ec6 127 SUPERFAMILY SSF54637 4 126 8.4E-29 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_06335 6a4387f378115b0bf0cff57645c40ec6 127 Pfam PF03061 Thioesterase superfamily 37 115 1.6E-12 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_09045 9ff0ce1351628d78143a0bdeb5cb4177 689 Gene3D G3DSA:3.40.720.10 317 624 2.3E-42 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_09045 9ff0ce1351628d78143a0bdeb5cb4177 689 SUPERFAMILY SSF53649 396 623 4.14E-21 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_09045 9ff0ce1351628d78143a0bdeb5cb4177 689 Pfam PF00884 Sulfatase 323 619 5.2E-38 T 15-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I28_25120 e152ad85ed03941b7aa93676ae0f2bb8 135 Pfam PF03551 Transcriptional regulator PadR-like family 52 116 1.0E-11 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_25120 e152ad85ed03941b7aa93676ae0f2bb8 135 SUPERFAMILY SSF46785 45 124 5.6E-13 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25120 e152ad85ed03941b7aa93676ae0f2bb8 135 Gene3D G3DSA:1.10.10.10 24 134 2.2E-14 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01835 0825d7ef07e4bc0b3479530cb6db9fb9 280 SUPERFAMILY SSF82549 1 279 9.42E-90 T 15-10-2018 C2I28_01835 0825d7ef07e4bc0b3479530cb6db9fb9 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 277 1.2E-98 T 15-10-2018 IPR003797 DegV C2I28_01835 0825d7ef07e4bc0b3479530cb6db9fb9 280 Gene3D G3DSA:3.40.50.10170 1 152 1.3E-53 T 15-10-2018 C2I28_01835 0825d7ef07e4bc0b3479530cb6db9fb9 280 Gene3D G3DSA:3.30.1180.10 153 279 4.2E-36 T 15-10-2018 C2I28_01835 0825d7ef07e4bc0b3479530cb6db9fb9 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 4.6E-92 T 15-10-2018 IPR003797 DegV C2I28_04485 019f5b2d71697c94c1d510ef266f7d17 171 Pfam PF13242 HAD-hyrolase-like 91 136 8.1E-11 T 15-10-2018 C2I28_04485 019f5b2d71697c94c1d510ef266f7d17 171 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 3 165 2.2E-58 T 15-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like C2I28_04485 019f5b2d71697c94c1d510ef266f7d17 171 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 57 130 1.6E-7 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_04485 019f5b2d71697c94c1d510ef266f7d17 171 Gene3D G3DSA:3.40.50.1000 20 154 1.9E-22 T 15-10-2018 IPR023214 HAD superfamily C2I28_04485 019f5b2d71697c94c1d510ef266f7d17 171 SUPERFAMILY SSF56784 15 150 3.51E-25 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_04485 019f5b2d71697c94c1d510ef266f7d17 171 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 1.1E-21 T 15-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 C2I28_03550 0395915a055faad3c94408c280d77a51 297 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 297 59.271 T 15-10-2018 IPR023009 Tyrosine recombinase XerC/XerD C2I28_03550 0395915a055faad3c94408c280d77a51 297 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 297 7.7E-104 T 15-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 C2I28_03550 0395915a055faad3c94408c280d77a51 297 Pfam PF00589 Phage integrase family 110 283 1.7E-57 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_03550 0395915a055faad3c94408c280d77a51 297 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 6 297 4.7E-124 T 15-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 C2I28_03550 0395915a055faad3c94408c280d77a51 297 Gene3D G3DSA:1.10.150.130 2 98 1.2E-22 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_03550 0395915a055faad3c94408c280d77a51 297 SUPERFAMILY SSF47823 3 99 2.75E-20 T 15-10-2018 C2I28_03550 0395915a055faad3c94408c280d77a51 297 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 297 62.106 T 15-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 C2I28_03550 0395915a055faad3c94408c280d77a51 297 Gene3D G3DSA:1.10.443.10 110 291 1.2E-69 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_03550 0395915a055faad3c94408c280d77a51 297 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 89 8.3E-22 T 15-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I28_03550 0395915a055faad3c94408c280d77a51 297 SUPERFAMILY SSF56349 105 295 1.56E-62 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_19040 ae6716c5201b42606f6adb14c4cc34c7 226 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 29 225 6.5E-41 T 15-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 C2I28_19040 ae6716c5201b42606f6adb14c4cc34c7 226 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 25 226 21.272 T 15-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 C2I28_19040 ae6716c5201b42606f6adb14c4cc34c7 226 SUPERFAMILY SSF52374 24 225 9.19E-40 T 15-10-2018 C2I28_19040 ae6716c5201b42606f6adb14c4cc34c7 226 Pfam PF01467 Cytidylyltransferase-like 29 199 3.6E-21 T 15-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I28_19040 ae6716c5201b42606f6adb14c4cc34c7 226 Gene3D G3DSA:3.40.50.620 21 226 2.2E-50 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 Gene3D G3DSA:3.40.1190.10 101 307 2.0E-65 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 Gene3D G3DSA:3.40.50.720 10 94 7.0E-31 T 15-10-2018 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 Pfam PF08245 Mur ligase middle domain 116 289 9.3E-34 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 SUPERFAMILY SSF51984 6 99 9.94E-19 T 15-10-2018 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 Gene3D G3DSA:3.90.190.20 314 447 3.3E-42 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 SUPERFAMILY SSF53623 102 307 1.31E-50 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 448 34.877 T 15-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 446 4.4E-136 T 15-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 SUPERFAMILY SSF53244 309 448 1.24E-39 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_02960 98072360dfd2efa3c99b0a6d7aa31045 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 376 1.2E-8 T 15-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 437 453 - T 15-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 247 3.0E-102 T 15-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 Gene3D G3DSA:3.40.1010.10 1 117 3.1E-33 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 214 8.2E-38 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 417 515 1.1E-8 T 15-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 SUPERFAMILY SSF53790 1 257 2.88E-59 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 Gene3D G3DSA:3.30.413.10 395 528 2.8E-18 T 15-10-2018 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 SUPERFAMILY SSF56014 398 516 2.88E-21 T 15-10-2018 C2I28_21215 019fa8279c5dc8bc1f13045ed830e859 540 Gene3D G3DSA:3.30.950.10 118 248 4.3E-54 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_26670 bf91359113160e3f4e3b55c6cc48ac29 186 SMART SM00860 24 167 4.7E-4 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_26670 bf91359113160e3f4e3b55c6cc48ac29 186 Gene3D G3DSA:3.40.1580.10 5 173 4.4E-18 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_26670 bf91359113160e3f4e3b55c6cc48ac29 186 Pfam PF14568 SMI1-KNR4 cell-wall 27 165 7.3E-11 T 15-10-2018 C2I28_26670 bf91359113160e3f4e3b55c6cc48ac29 186 SUPERFAMILY SSF160631 20 170 4.05E-15 T 15-10-2018 C2I28_12085 ac373f7197721afabcd116462e145c75 226 Pfam PF04172 LrgB-like family 10 223 4.0E-68 T 15-10-2018 IPR007300 CidB/LrgB family C2I28_12085 ac373f7197721afabcd116462e145c75 226 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 226 31.448 T 15-10-2018 IPR024891 Antiholin-like protein LrgB C2I28_03875 cd2c9275eb14c667a11d16d2c74f8467 214 Gene3D G3DSA:3.30.300.270 100 214 5.6E-39 T 15-10-2018 IPR038503 Stage III sporulation protein AH-like superfamily C2I28_03875 cd2c9275eb14c667a11d16d2c74f8467 214 Pfam PF12685 SpoIIIAH-like protein 6 202 7.2E-42 T 15-10-2018 IPR024232 Stage III sporulation protein AH-like C2I28_09165 16402285a3a347bd0c860d1113338d4d 133 Gene3D G3DSA:3.30.565.10 4 130 9.6E-17 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09165 16402285a3a347bd0c860d1113338d4d 133 SMART SM00387 34 133 1.0E-4 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09165 16402285a3a347bd0c860d1113338d4d 133 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 127 2.1E-7 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09165 16402285a3a347bd0c860d1113338d4d 133 SUPERFAMILY SSF55874 22 126 3.14E-15 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_05395 09a8188743525db54bfdca84165ee0de 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 9.6E-42 T 15-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 2.7E-162 T 15-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 46.343 T 15-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 306 3.6E-27 T 15-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 Gene3D G3DSA:3.40.50.720 1 149 6.8E-60 T 15-10-2018 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 SUPERFAMILY SSF56327 151 308 1.59E-51 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 Gene3D G3DSA:3.90.110.10 150 309 3.5E-61 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 SUPERFAMILY SSF51735 4 147 4.12E-48 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05395 09a8188743525db54bfdca84165ee0de 312 PIRSF PIRSF000102 2 309 1.1E-105 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 2.7E-31 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 2.7E-31 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 2.7E-31 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 2.7E-31 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_05395 09a8188743525db54bfdca84165ee0de 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 2.7E-31 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_23695 9f5c40501fd8044f9b98e79014c78b5c 191 Gene3D G3DSA:1.10.357.10 54 186 1.2E-13 T 15-10-2018 C2I28_23695 9f5c40501fd8044f9b98e79014c78b5c 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 8.4E-18 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_23695 9f5c40501fd8044f9b98e79014c78b5c 191 Gene3D G3DSA:1.10.10.60 6 53 1.6E-20 T 15-10-2018 C2I28_23695 9f5c40501fd8044f9b98e79014c78b5c 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.6E-12 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_23695 9f5c40501fd8044f9b98e79014c78b5c 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.6E-12 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_23695 9f5c40501fd8044f9b98e79014c78b5c 191 SUPERFAMILY SSF46689 3 82 4.74E-20 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 168 2.9E-53 T 15-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 Gene3D G3DSA:2.40.30.60 4 91 3.7E-21 T 15-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 Pfam PF01782 RimM N-terminal domain 5 90 7.3E-23 T 15-10-2018 IPR002676 RimM, N-terminal GO:0006364 C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 SUPERFAMILY SSF50447 2 91 3.53E-21 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 Pfam PF05239 PRC-barrel domain 97 169 8.5E-14 T 15-10-2018 IPR027275 PRC-barrel domain C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 168 24.428 T 15-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 SUPERFAMILY SSF50346 99 168 2.83E-21 T 15-10-2018 IPR011033 PRC-barrel-like superfamily C2I28_02620 2551f281ba4805ff99f7a7309bd86a9a 170 Gene3D G3DSA:2.30.30.240 94 170 1.9E-22 T 15-10-2018 C2I28_09445 c2f7a1d97bc5f50f26600aa36bbf1046 83 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 75 7.0E-23 T 15-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09445 c2f7a1d97bc5f50f26600aa36bbf1046 83 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 77 1.6E-31 T 15-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09445 c2f7a1d97bc5f50f26600aa36bbf1046 83 Gene3D G3DSA:3.30.1280.10 1 83 5.8E-34 T 15-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09445 c2f7a1d97bc5f50f26600aa36bbf1046 83 SUPERFAMILY SSF82697 2 77 1.74E-28 T 15-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09445 c2f7a1d97bc5f50f26600aa36bbf1046 83 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 79 3.7E-31 T 15-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09445 c2f7a1d97bc5f50f26600aa36bbf1046 83 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 77 22.187 T 15-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_11930 b3e765df14a3f7147ed703b5f21d8d7d 178 SUPERFAMILY SSF101307 15 164 4.84E-48 T 15-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 C2I28_11930 b3e765df14a3f7147ed703b5f21d8d7d 178 Gene3D G3DSA:1.10.3760.10 4 175 4.1E-69 T 15-10-2018 C2I28_11930 b3e765df14a3f7147ed703b5f21d8d7d 178 PIRSF PIRSF019587 8 170 1.0E-67 T 15-10-2018 IPR026038 Putative phosphatidylglycerophosphatase C2I28_11930 b3e765df14a3f7147ed703b5f21d8d7d 178 Pfam PF04608 Phosphatidylglycerophosphatase A 23 161 1.3E-19 T 15-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 Gene3D G3DSA:3.40.50.920 537 664 3.4E-41 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 662 1.1E-274 T 15-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 Gene3D G3DSA:3.40.50.970 334 536 3.2E-75 T 15-10-2018 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 SUPERFAMILY SSF52518 345 525 3.54E-67 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 15-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 336 1.7E-148 T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 SUPERFAMILY SSF52922 531 663 4.97E-38 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 SUPERFAMILY SSF52518 4 323 9.64E-116 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 Pfam PF02779 Transketolase, pyrimidine binding domain 352 523 1.0E-45 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 SMART SM00861 353 524 3.2E-67 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 Pfam PF02780 Transketolase, C-terminal domain 547 654 1.0E-9 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_24250 fb38ad27c8f066c3dcf3215458d31c7e 664 Gene3D G3DSA:3.40.50.970 1 333 1.2E-128 T 15-10-2018 C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 SMART SM00267 405 578 4.3E-54 T 15-10-2018 IPR000160 GGDEF domain C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 414 577 3.8E-36 T 15-10-2018 IPR000160 GGDEF domain C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 Gene3D G3DSA:1.20.1480.50 319 409 6.6E-13 T 15-10-2018 C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 SUPERFAMILY SSF55073 421 580 5.89E-46 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 Gene3D G3DSA:3.30.70.270 411 591 5.6E-53 T 15-10-2018 C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 SUPERFAMILY SSF141868 593 841 4.18E-84 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 Pfam PF00563 EAL domain 595 830 1.4E-71 T 15-10-2018 IPR001633 EAL domain C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 Gene3D G3DSA:3.20.20.450 592 842 3.2E-94 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 SMART SM00304 351 403 1.0E-4 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 Pfam PF00672 HAMP domain 352 395 2.5E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 Pfam PF00990 Diguanylate cyclase, GGDEF domain 416 574 1.4E-43 T 15-10-2018 IPR000160 GGDEF domain C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 SUPERFAMILY SSF158472 352 401 4.18E-8 T 15-10-2018 C2I28_13550 b6bba2ed9753cd2d37d4b8d72b8ff026 843 SMART SM00052 588 835 7.1E-102 T 15-10-2018 IPR001633 EAL domain C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 SUPERFAMILY SSF48403 7 159 1.29E-42 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 Pfam PF12796 Ankyrin repeats (3 copies) 7 101 3.7E-16 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 Pfam PF12796 Ankyrin repeats (3 copies) 105 160 2.4E-9 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 Gene3D G3DSA:1.25.40.20 3 69 7.3E-15 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 SMART SM00248 2 32 1400.0 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 SMART SM00248 137 165 1.8 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 SMART SM00248 71 100 0.013 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 SMART SM00248 36 65 4.0E-6 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 SMART SM00248 104 133 0.0086 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 PRINTS PR01415 Ankyrin repeat signature 87 101 2.5E-8 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 PRINTS PR01415 Ankyrin repeat signature 37 52 2.5E-8 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_25340 52aa8d3c2ed9ace14a02e3df90c21dc4 165 Gene3D G3DSA:1.25.40.20 70 164 1.4E-29 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_13435 5e78455b8625d062464c4f74dc866bd9 154 Pfam PF00877 NlpC/P60 family 49 152 4.9E-37 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_13435 5e78455b8625d062464c4f74dc866bd9 154 Gene3D G3DSA:3.90.1720.10 27 154 2.8E-47 T 15-10-2018 C2I28_13435 5e78455b8625d062464c4f74dc866bd9 154 SUPERFAMILY SSF54001 37 154 4.32E-46 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 4.2E-5 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 4.2E-5 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 4.2E-5 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 SMART SM00422 3 72 3.4E-21 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 SUPERFAMILY SSF46955 2 113 6.23E-29 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 Pfam PF13411 MerR HTH family regulatory protein 3 70 5.8E-20 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 Gene3D G3DSA:1.10.1660.10 1 124 1.1E-33 T 15-10-2018 C2I28_24350 a4b0185b2897f84547e92273cf4b466b 127 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 Pfam PF01546 Peptidase family M20/M25/M40 81 405 1.8E-32 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 Gene3D G3DSA:3.40.630.10 18 403 1.0E-136 T 15-10-2018 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 408 5.8E-124 T 15-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 SUPERFAMILY SSF53187 7 409 2.62E-89 T 15-10-2018 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 Gene3D G3DSA:3.30.70.360 213 327 1.0E-136 T 15-10-2018 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 PIRSF PIRSF001235 5 411 7.6E-138 T 15-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 C2I28_21410 909e61272551f9b7c02d743282d501b4 411 SUPERFAMILY SSF55031 213 326 8.02E-22 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_14670 c3e9ab25231078385ac5f78715fc77d9 78 Pfam PF00462 Glutaredoxin 4 63 3.8E-13 T 15-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 C2I28_14670 c3e9ab25231078385ac5f78715fc77d9 78 Gene3D G3DSA:3.40.30.10 1 78 9.3E-21 T 15-10-2018 C2I28_14670 c3e9ab25231078385ac5f78715fc77d9 78 SUPERFAMILY SSF52833 3 74 3.25E-14 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 Gene3D G3DSA:3.10.105.10 302 520 7.2E-178 T 15-10-2018 C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 PIRSF PIRSF002741 5 546 1.1E-129 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 Gene3D G3DSA:3.90.76.10 80 202 7.2E-178 T 15-10-2018 C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 Gene3D G3DSA:3.40.190.10 59 534 7.2E-178 T 15-10-2018 C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 468 3.5E-88 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 96 118 - T 15-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I28_15405 68eb96ebe874599a83797c2ab7bcf60e 547 SUPERFAMILY SSF53850 44 541 2.82E-140 T 15-10-2018 C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 ProSitePatterns PS00892 HIT domain signature. 90 108 - T 15-10-2018 IPR019808 Histidine triad, conserved site C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 SUPERFAMILY SSF54197 6 141 1.19E-47 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 PRINTS PR00332 Histidine triad family signature 97 107 3.2E-18 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 PRINTS PR00332 Histidine triad family signature 30 48 3.2E-18 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 PRINTS PR00332 Histidine triad family signature 9 25 3.2E-18 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 Pfam PF01230 HIT domain 15 110 1.0E-27 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_11110 34ac5babff68c72727cf2bfe1a66335c 144 Gene3D G3DSA:3.30.428.10 1 144 2.3E-51 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 SUPERFAMILY SSF75005 45 363 8.37E-86 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 SUPERFAMILY SSF49899 362 519 3.48E-28 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 Gene3D G3DSA:2.60.120.560 367 521 1.5E-36 T 15-10-2018 C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 Gene3D G3DSA:2.115.10.20 50 364 1.9E-101 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 SMART SM00640 53 481 8.2E-119 T 15-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 53 362 2.1E-81 T 15-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I28_15775 20171ca5da399ff93eff3e5a33641682 521 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 365 515 5.3E-25 T 15-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 SUPERFAMILY SSF55261 294 421 3.43E-45 T 15-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 559 5.6E-114 T 15-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 35.017 T 15-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Gene3D G3DSA:3.30.1360.30 277 421 1.1E-198 T 15-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Gene3D G3DSA:2.40.50.140 1 109 8.3E-35 T 15-10-2018 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 9.4E-27 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 9.4E-27 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 9.4E-27 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 9.4E-27 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 SUPERFAMILY SSF55681 114 586 8.23E-111 T 15-10-2018 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 587 2.6E-266 T 15-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 3.7E-16 T 15-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 SUPERFAMILY SSF50249 4 108 7.05E-33 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Pfam PF02938 GAD domain 313 407 1.4E-34 T 15-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 C2I28_04680 225258dacbf79ee9665fc4293f4bca2a 592 Gene3D G3DSA:3.30.930.10 121 584 1.1E-198 T 15-10-2018 C2I28_17060 34e4154e5168000b9f275427a5804a84 248 Gene3D G3DSA:3.40.50.880 3 247 3.4E-79 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_17060 34e4154e5168000b9f275427a5804a84 248 SUPERFAMILY SSF52317 29 240 2.22E-41 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_17060 34e4154e5168000b9f275427a5804a84 248 Pfam PF07722 Peptidase C26 4 218 1.6E-69 T 15-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 SMART SM00966 177 222 1.5E-4 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 SMART SM00966 61 104 2.3E-4 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 SUPERFAMILY SSF89447 57 103 1.11E-9 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 SUPERFAMILY SSF89447 173 218 1.44E-7 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 Gene3D G3DSA:2.10.260.10 171 220 2.8E-9 T 15-10-2018 C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 177 217 2.2E-9 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_00790 4780a6dfbefe3bacff8710ff5ec8ee28 241 Gene3D G3DSA:2.10.260.10 46 102 4.3E-16 T 15-10-2018 C2I28_03640 8db6ebfa4d3f36b5fe6fd100533b918d 338 SUPERFAMILY SSF51395 3 333 8.74E-113 T 15-10-2018 C2I28_03640 8db6ebfa4d3f36b5fe6fd100533b918d 338 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 66.82 T 15-10-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 C2I28_03640 8db6ebfa4d3f36b5fe6fd100533b918d 338 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 325 3.9E-93 T 15-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 C2I28_03640 8db6ebfa4d3f36b5fe6fd100533b918d 338 Gene3D G3DSA:3.20.20.70 2 338 5.3E-128 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 SUPERFAMILY SSF53383 13 359 5.17E-82 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 360 61.777 T 15-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 Pfam PF00155 Aminotransferase class I and II 30 354 1.4E-59 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 15-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 Gene3D G3DSA:3.40.640.10 43 268 2.7E-117 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 358 1.4E-112 T 15-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 C2I28_03165 d9a26c355a825190bd1b710c2f364b31 367 Gene3D G3DSA:3.90.1150.10 20 350 2.7E-117 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 Pfam PF00813 FliP family 25 217 7.3E-84 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 5.1E-67 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 5.1E-67 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 5.1E-67 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 5.1E-67 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 5.1E-67 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 5.1E-67 T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 3.0E-24 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 3.0E-24 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 3.0E-24 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 3.0E-24 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 3.0E-24 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 3.0E-24 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 1.0E-92 T 15-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 C2I28_02455 cb0d390d7263dcabdccb7757f4f332a8 222 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 15-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 Pfam PF03315 Serine dehydratase beta chain 5 90 5.3E-13 T 15-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 Gene3D G3DSA:3.30.70.260 140 218 2.6E-15 T 15-10-2018 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 SUPERFAMILY SSF143548 19 137 7.85E-31 T 15-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 SUPERFAMILY SSF55021 137 217 2.54E-16 T 15-10-2018 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.0E-89 T 15-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 Gene3D G3DSA:3.30.1330.90 13 136 1.8E-20 T 15-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 C2I28_02700 1750d2d173225225f2d12367faeffad8 220 Pfam PF01842 ACT domain 149 210 6.9E-10 T 15-10-2018 IPR002912 ACT domain C2I28_02700 1750d2d173225225f2d12367faeffad8 220 PIRSF PIRSF036692 1 220 6.3E-104 T 15-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Gene3D G3DSA:3.40.50.360 57 220 2.6E-50 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00369 Flavodoxin signature 148 158 3.3E-15 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00369 Flavodoxin signature 172 191 3.3E-15 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00369 Flavodoxin signature 68 81 3.3E-15 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00369 Flavodoxin signature 116 127 3.3E-15 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 7 602 2.5E-271 T 15-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Pfam PF00175 Oxidoreductase NAD-binding domain 460 566 1.7E-17 T 15-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Pfam PF00667 FAD binding domain 230 425 8.5E-34 T 15-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PIRSF PIRSF000207 1 602 5.4E-269 T 15-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Gene3D G3DSA:3.40.50.80 448 602 3.8E-59 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 528 544 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 484 493 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 270 280 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 389 396 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 459 478 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 497 508 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 551 559 2.8E-27 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Gene3D G3DSA:2.40.30.10 232 442 2.3E-76 T 15-10-2018 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 SUPERFAMILY SSF52218 65 211 2.27E-48 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 SUPERFAMILY SSF52343 447 602 6.16E-51 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Gene3D G3DSA:1.20.990.10 280 387 2.3E-76 T 15-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 SUPERFAMILY SSF63380 228 448 2.09E-66 T 15-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I28_23595 4320721a5804a74d7d2ffd0d279b9f7b 602 Pfam PF00258 Flavodoxin 69 200 7.6E-32 T 15-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 C2I28_13115 a59e9518b983429bbadd651b953148fb 113 Gene3D G3DSA:1.10.3730.20 1 109 5.5E-32 T 15-10-2018 C2I28_13115 a59e9518b983429bbadd651b953148fb 113 SUPERFAMILY SSF103481 4 104 2.09E-18 T 15-10-2018 C2I28_13115 a59e9518b983429bbadd651b953148fb 113 Pfam PF00893 Small Multidrug Resistance protein 1 92 1.1E-29 T 15-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I28_06875 53b045983bac3960f290d4cb192aede9 328 Hamap MF_00973 Gluconeogenesis factor. 5 319 36.319 T 15-10-2018 IPR010119 Gluconeogenesis factor C2I28_06875 53b045983bac3960f290d4cb192aede9 328 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 317 2.4E-128 T 15-10-2018 IPR010119 Gluconeogenesis factor C2I28_06875 53b045983bac3960f290d4cb192aede9 328 Gene3D G3DSA:3.40.50.12300 4 323 9.1E-133 T 15-10-2018 IPR038136 Gluconeogenesis factor superfamily C2I28_06875 53b045983bac3960f290d4cb192aede9 328 SUPERFAMILY SSF142338 7 314 7.72E-109 T 15-10-2018 C2I28_06875 53b045983bac3960f290d4cb192aede9 328 Pfam PF01933 Uncharacterised protein family UPF0052 9 294 6.0E-110 T 15-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 C2I28_26975 e5c519cdc28c47c6471627510182e19f 193 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 118 182 1.8E-21 T 15-10-2018 IPR018656 Domain of unknown function DUF2087 C2I28_26975 e5c519cdc28c47c6471627510182e19f 193 SUPERFAMILY SSF46785 1 191 1.13E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26975 e5c519cdc28c47c6471627510182e19f 193 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 1.3E-10 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_26975 e5c519cdc28c47c6471627510182e19f 193 Gene3D G3DSA:1.10.10.10 1 94 7.3E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26975 e5c519cdc28c47c6471627510182e19f 193 SMART SM00418 8 85 3.3E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 195 2.7E-35 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Hamap MF_01669 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase [iolD]. 1 644 59.793 T 15-10-2018 IPR023757 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, Firmicutes GO:0000287|GO:0016787|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Gene3D G3DSA:3.40.50.1220 213 407 1.9E-34 T 15-10-2018 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 SUPERFAMILY SSF52518 1 209 1.06E-34 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Gene3D G3DSA:3.40.50.970 414 625 7.2E-44 T 15-10-2018 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Gene3D G3DSA:3.40.50.970 1 212 3.1E-33 T 15-10-2018 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 SUPERFAMILY SSF52518 417 632 3.32E-52 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 SUPERFAMILY SSF52467 185 363 1.9E-38 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 352 8.0E-32 T 15-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 599 7.1E-39 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 5 640 3.7E-297 T 15-10-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 C2I28_10610 7008083a44c48f67a532feb09dedcfa9 644 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 476 495 - T 15-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 30 393 1.2E-127 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 14 425 37.375 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 PRINTS PR00447 Natural resistance-associated macrophage protein signature 315 334 7.4E-34 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 PRINTS PR00447 Natural resistance-associated macrophage protein signature 138 157 7.4E-34 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 PRINTS PR00447 Natural resistance-associated macrophage protein signature 213 236 7.4E-34 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 PRINTS PR00447 Natural resistance-associated macrophage protein signature 110 136 7.4E-34 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 PRINTS PR00447 Natural resistance-associated macrophage protein signature 163 184 7.4E-34 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_20730 8d0770b385bc1d0f91d1e9f09ac20a55 426 Pfam PF01566 Natural resistance-associated macrophage protein 51 399 3.2E-115 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_05305 160dd5697182c30e11f7738980f29509 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 Gene3D G3DSA:1.10.1900.20 56 118 1.0E-28 T 15-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.7E-41 T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.7E-41 T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.7E-41 T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 8.0E-52 T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 1.0E-11 T 15-10-2018 C2I28_05305 160dd5697182c30e11f7738980f29509 119 SUPERFAMILY SSF74731 2 115 1.29E-50 T 15-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.522 T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05305 160dd5697182c30e11f7738980f29509 119 Gene3D G3DSA:1.10.720.90 2 55 1.7E-26 T 15-10-2018 C2I28_05305 160dd5697182c30e11f7738980f29509 119 Pfam PF00453 Ribosomal protein L20 3 109 2.6E-50 T 15-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 SUPERFAMILY SSF56024 34 158 3.93E-13 T 15-10-2018 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Gene3D G3DSA:3.40.50.300 174 354 4.6E-46 T 15-10-2018 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Pfam PF11907 Domain of unknown function (DUF3427) 669 931 5.8E-68 T 15-10-2018 IPR021835 Protein of unknown function DUF3427 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 SMART SM00490 435 518 1.1E-11 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Gene3D G3DSA:3.30.870.10 5 170 6.8E-35 T 15-10-2018 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Pfam PF00271 Helicase conserved C-terminal domain 421 516 7.2E-12 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Pfam PF13091 PLD-like domain 27 152 2.5E-15 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 SMART SM00487 188 369 1.9E-17 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Gene3D G3DSA:3.40.50.300 358 541 4.1E-38 T 15-10-2018 C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 SUPERFAMILY SSF52540 237 539 5.69E-47 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07830 d02bbd30912b6adf074bdcbd3b62ea16 934 Pfam PF04851 Type III restriction enzyme, res subunit 192 339 8.6E-33 T 15-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I28_20995 fbe029e1335eb2e4dbf6b7cd4f6a6a19 184 Pfam PF10400 Virulence activator alpha C-term 97 176 5.0E-16 T 15-10-2018 IPR018309 Transcription regulator PadR, C-terminal C2I28_20995 fbe029e1335eb2e4dbf6b7cd4f6a6a19 184 Pfam PF03551 Transcriptional regulator PadR-like family 10 83 4.5E-16 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_20995 fbe029e1335eb2e4dbf6b7cd4f6a6a19 184 SUPERFAMILY SSF46785 6 176 1.44E-39 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20995 fbe029e1335eb2e4dbf6b7cd4f6a6a19 184 Gene3D G3DSA:1.10.10.10 5 92 1.0E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 Gene3D G3DSA:3.90.1150.10 13 370 3.3E-139 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 Gene3D G3DSA:3.40.640.10 47 286 3.3E-139 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 380 68.605 T 15-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 Pfam PF00202 Aminotransferase class-III 10 376 3.3E-127 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 PIRSF PIRSF000521 5 114 2.3E-8 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 PIRSF PIRSF000521 154 380 1.7E-41 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 PIRSF PIRSF000521 107 144 0.0048 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 SUPERFAMILY SSF53383 4 378 1.2E-127 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_11560 d6d6b1a0341198296bff4ef454c2089b 384 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 377 3.9E-153 T 15-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 Gene3D G3DSA:3.40.30.60 343 486 3.8E-53 T 15-10-2018 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 15-10-2018 IPR025505 FHIPEP conserved site C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 2.2E-55 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 2.2E-55 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 2.2E-55 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 2.2E-55 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 2.2E-55 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 2.2E-55 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 Pfam PF00771 FHIPEP family 15 668 5.3E-273 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 PIRSF PIRSF005419 1 678 2.0E-257 T 15-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 Gene3D G3DSA:1.10.8.540 487 575 3.5E-30 T 15-10-2018 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 Gene3D G3DSA:1.10.490.80 578 676 9.6E-29 T 15-10-2018 C2I28_02435 5ff37eb76ca8a29e588edab830901641 678 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 676 1.8E-271 T 15-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 SUPERFAMILY SSF56014 263 351 9.49E-14 T 15-10-2018 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 SUPERFAMILY SSF51717 18 214 4.71E-16 T 15-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 34.981 T 15-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 PIRSF PIRSF004640 1 361 4.1E-156 T 15-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 Gene3D G3DSA:3.30.413.10 260 360 7.1E-36 T 15-10-2018 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 Pfam PF04551 GcpE protein 10 351 2.6E-140 T 15-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 Gene3D G3DSA:3.20.20.20 1 259 6.4E-110 T 15-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_04185 6dca0bf583ff7cdf6ea95c774dd6f96b 370 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 2.4E-131 T 15-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 SUPERFAMILY SSF54980 304 389 1.26E-15 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 SUPERFAMILY SSF54980 400 515 8.15E-29 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 SMART SM00838 397 482 1.6E-4 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Pfam PF03144 Elongation factor Tu domain 2 221 291 2.5E-13 T 15-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 PRINTS PR00315 GTP-binding elongation factor signature 89 100 3.2E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 PRINTS PR00315 GTP-binding elongation factor signature 9 22 3.2E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 PRINTS PR00315 GTP-binding elongation factor signature 53 61 3.2E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 PRINTS PR00315 GTP-binding elongation factor signature 125 134 3.2E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 PRINTS PR00315 GTP-binding elongation factor signature 73 83 3.2E-14 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 SUPERFAMILY SSF50447 154 301 4.99E-32 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Gene3D G3DSA:3.40.50.300 4 200 1.7E-67 T 15-10-2018 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Gene3D G3DSA:2.40.50.250 485 601 1.4E-129 T 15-10-2018 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Pfam PF00679 Elongation factor G C-terminus 399 479 6.1E-24 T 15-10-2018 IPR000640 Elongation factor EFG, domain V-like C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Pfam PF14492 Elongation Factor G, domain II 330 383 7.4E-7 T 15-10-2018 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Gene3D G3DSA:3.30.70.240 391 484 1.4E-129 T 15-10-2018 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Gene3D G3DSA:2.40.30.10 201 301 1.1E-33 T 15-10-2018 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 601 6.6E-292 T 15-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 15-10-2018 IPR031157 Tr-type G domain, conserved site C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 SUPERFAMILY SSF52540 3 209 1.92E-56 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Gene3D G3DSA:3.30.70.870 308 592 1.4E-129 T 15-10-2018 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 3.6E-56 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_14840 96b334ee790cb80e1983505e2d0fc45e 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 148 9.2E-23 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 3.0E-11 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 SMART SM00388 239 305 2.7E-11 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 SUPERFAMILY SSF55874 309 449 2.36E-26 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 Pfam PF00672 HAMP domain 186 234 3.6E-8 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 SUPERFAMILY SSF47384 224 303 1.8E-14 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 SMART SM00387 348 447 3.5E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 Gene3D G3DSA:1.10.287.130 235 304 1.1E-14 T 15-10-2018 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 Gene3D G3DSA:1.10.8.500 185 234 1.4E-8 T 15-10-2018 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 Gene3D G3DSA:3.30.565.10 311 449 3.7E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 3.1E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 3.1E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 3.1E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 3.1E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 448 3.2E-12 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 SMART SM00304 186 238 2.7E-8 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_01135 1f590e47f04d2c027ec3f5c63b0c9968 449 SUPERFAMILY SSF158472 186 234 2.22E-8 T 15-10-2018 C2I28_20150 5fef21913e44b6a07139dfea12ebe7e9 182 Pfam PF13328 HD domain 7 131 1.2E-20 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_20150 5fef21913e44b6a07139dfea12ebe7e9 182 SMART SM00471 23 129 2.5E-9 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_20150 5fef21913e44b6a07139dfea12ebe7e9 182 SUPERFAMILY SSF109604 2 134 5.23E-37 T 15-10-2018 C2I28_20150 5fef21913e44b6a07139dfea12ebe7e9 182 Gene3D G3DSA:1.10.3210.10 2 162 1.9E-43 T 15-10-2018 C2I28_15270 0f9a1a18a1217ec3ca013b2bf79a6a5c 197 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 190 8.7E-82 T 15-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 C2I28_15270 0f9a1a18a1217ec3ca013b2bf79a6a5c 197 Gene3D G3DSA:3.40.50.2020 3 188 5.5E-51 T 15-10-2018 C2I28_15270 0f9a1a18a1217ec3ca013b2bf79a6a5c 197 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.45 T 15-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 C2I28_15270 0f9a1a18a1217ec3ca013b2bf79a6a5c 197 SUPERFAMILY SSF53271 1 188 7.74E-42 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_15270 0f9a1a18a1217ec3ca013b2bf79a6a5c 197 Pfam PF00156 Phosphoribosyl transferase domain 49 156 3.5E-7 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_11705 5f47d0028634561df2ce3297a23fe440 311 SUPERFAMILY SSF161098 88 291 5.01E-19 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11705 5f47d0028634561df2ce3297a23fe440 311 Gene3D G3DSA:1.10.3720.10 85 299 2.3E-20 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11705 5f47d0028634561df2ce3297a23fe440 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 7.6E-41 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 910 1000 4.14E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 731 818 7.0E-8 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 185 273 1.71E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1734 1819 8.1E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 2006 2094 5.9E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1551 1636 8.1E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1915 2002 1.1E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1366 1453 1.0E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 907 996 1.0E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 270 358 1.7E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 542 631 2.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 452 540 4.5E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 816 904 1.0E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1185 1270 6.8E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 360 449 2.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1823 1911 4.7E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 725 813 6.1E-7 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 178 267 2.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1 85 3.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 88 176 2.2E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 1091 1179 1.2E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 Gene3D G3DSA:2.60.40.10 634 722 2.2E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1103 1183 2.71E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 4 91 3.85E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 94 181 6.42E-8 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1824 1915 7.69E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 276 363 2.14E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 549 637 1.57E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 822 909 4.85E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1282 1366 5.73E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 458 545 1.71E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1920 2007 8.71E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1737 1824 1.38E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 747 830 0.003 T 15-10-2018 IPR010221 VCBS repeat C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 640 727 6.28E-8 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1554 1641 1.57E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 1371 1458 2.04E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SUPERFAMILY SSF49313 367 455 1.57E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 838 911 0.36 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 1845 1918 1.7 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 929 1003 1.4 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 201 274 0.14 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 1570 1643 0.73 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 383 456 0.14 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 1753 1826 0.73 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 565 638 0.14 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 474 547 0.6 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 1204 1277 0.55 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 19 92 0.18 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 747 820 0.11 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 1387 1460 0.92 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 292 365 0.59 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 656 729 0.47 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 110 183 0.53 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27725 fc1e4de7cc9f937bfc75ed822e4697d7 2186 SMART SM00112 1936 2009 0.8 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 4.6E-142 T 15-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PRINTS PR00148 Enolase signature 314 325 6.2E-47 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PRINTS PR00148 Enolase signature 366 383 6.2E-47 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PRINTS PR00148 Enolase signature 107 123 6.2E-47 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PRINTS PR00148 Enolase signature 337 351 6.2E-47 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PRINTS PR00148 Enolase signature 37 51 6.2E-47 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PRINTS PR00148 Enolase signature 161 174 6.2E-47 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 SMART SM01193 4 134 1.7E-105 T 15-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 SUPERFAMILY SSF51604 138 428 1.13E-131 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 SUPERFAMILY SSF54826 3 138 7.66E-63 T 15-10-2018 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 Gene3D G3DSA:3.30.390.10 1 127 4.4E-61 T 15-10-2018 IPR029017 Enolase-like, N-terminal C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 Pfam PF03952 Enolase, N-terminal domain 4 134 5.4E-64 T 15-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 SMART SM01192 139 428 1.0E-224 T 15-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 Gene3D G3DSA:3.20.20.120 128 431 2.4E-138 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 1.7E-219 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 Hamap MF_00318 Enolase [eno]. 2 414 46.576 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 PIRSF PIRSF001400 1 428 1.1E-197 T 15-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 C2I28_06810 08d3e7bbdf7fef375d37e476b9c2b346 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 15-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_12260 48ac4ec8cd7117f7c05943321d1a035a 245 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_12260 48ac4ec8cd7117f7c05943321d1a035a 245 SMART SM00382 36 224 2.5E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12260 48ac4ec8cd7117f7c05943321d1a035a 245 Gene3D G3DSA:3.40.50.300 7 242 2.8E-64 T 15-10-2018 C2I28_12260 48ac4ec8cd7117f7c05943321d1a035a 245 Pfam PF00005 ABC transporter 27 168 6.7E-29 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12260 48ac4ec8cd7117f7c05943321d1a035a 245 SUPERFAMILY SSF52540 8 240 6.2E-56 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07835 bf102c063e2c06381d3e82fc9dc0d39c 332 SUPERFAMILY SSF51395 13 319 5.0E-60 T 15-10-2018 C2I28_07835 bf102c063e2c06381d3e82fc9dc0d39c 332 PIRSF PIRSF006621 2 328 1.3E-84 T 15-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I28_07835 bf102c063e2c06381d3e82fc9dc0d39c 332 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 15-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I28_07835 bf102c063e2c06381d3e82fc9dc0d39c 332 Gene3D G3DSA:3.20.20.70 13 250 3.9E-62 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_07835 bf102c063e2c06381d3e82fc9dc0d39c 332 Pfam PF01207 Dihydrouridine synthase (Dus) 15 320 1.8E-50 T 15-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 C2I28_22965 d547f6fd2e7eb2b44dcf18dd2b2e464c 349 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 67 1.3E-13 T 15-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22965 d547f6fd2e7eb2b44dcf18dd2b2e464c 349 SUPERFAMILY SSF47648 5 70 5.1E-15 T 15-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22965 d547f6fd2e7eb2b44dcf18dd2b2e464c 349 Gene3D G3DSA:1.20.970.10 1 69 2.7E-22 T 15-10-2018 C2I28_22965 d547f6fd2e7eb2b44dcf18dd2b2e464c 349 Gene3D G3DSA:3.40.1030.10 83 347 1.5E-53 T 15-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22965 d547f6fd2e7eb2b44dcf18dd2b2e464c 349 Pfam PF00591 Glycosyl transferase family, a/b domain 91 332 1.0E-25 T 15-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22965 d547f6fd2e7eb2b44dcf18dd2b2e464c 349 SUPERFAMILY SSF52418 80 341 1.24E-44 T 15-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 475 68.214 T 15-10-2018 IPR022825 Lactate utilization protein B C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 SUPERFAMILY SSF46548 271 393 4.01E-17 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 Pfam PF02589 LUD domain 70 295 1.3E-56 T 15-10-2018 IPR003741 LUD domain C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 Gene3D G3DSA:3.40.50.10420 124 295 4.8E-15 T 15-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 19 455 8.3E-210 T 15-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 Pfam PF11870 Domain of unknown function (DUF3390) 384 469 4.0E-19 T 15-10-2018 IPR024569 4Fe-4S binding protein, C-terminal C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 Pfam PF13183 4Fe-4S dicluster domain 311 377 9.5E-10 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 SUPERFAMILY SSF100950 64 296 4.18E-39 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_14255 a83c9e84b1ef4b440944ac91dc6f1f74 479 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_15815 41d31ca659d3aed7f5ce9ac667d5397f 96 SUPERFAMILY SSF54909 1 92 1.17E-31 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_15815 41d31ca659d3aed7f5ce9ac667d5397f 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 78 4.8E-20 T 15-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I28_15815 41d31ca659d3aed7f5ce9ac667d5397f 96 Gene3D G3DSA:3.30.70.100 1 96 1.6E-31 T 15-10-2018 C2I28_03825 5e2e929e2becd730d64971698994c018 149 Gene3D G3DSA:3.30.1360.40 68 149 3.4E-33 T 15-10-2018 C2I28_03825 5e2e929e2becd730d64971698994c018 149 SUPERFAMILY SSF46785 5 78 7.54E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_03825 5e2e929e2becd730d64971698994c018 149 Gene3D G3DSA:1.10.10.10 4 67 1.4E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03825 5e2e929e2becd730d64971698994c018 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 4.6E-55 T 15-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I28_03825 5e2e929e2becd730d64971698994c018 149 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 2.1E-27 T 15-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 C2I28_03825 5e2e929e2becd730d64971698994c018 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 2.0E-26 T 15-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 C2I28_03825 5e2e929e2becd730d64971698994c018 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 72.805 T 15-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I28_03825 5e2e929e2becd730d64971698994c018 149 SUPERFAMILY SSF55252 80 149 3.01E-23 T 15-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 C2I28_03825 5e2e929e2becd730d64971698994c018 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 1.4E-30 T 15-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 C2I28_03825 5e2e929e2becd730d64971698994c018 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 6.8E-29 T 15-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I28_03825 5e2e929e2becd730d64971698994c018 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 6.8E-29 T 15-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I28_03825 5e2e929e2becd730d64971698994c018 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 6.8E-29 T 15-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I28_03825 5e2e929e2becd730d64971698994c018 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 6.8E-29 T 15-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 C2I28_14010 6188b674546971cec42935712bf92c72 451 Gene3D G3DSA:3.30.465.10 350 440 1.5E-14 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_14010 6188b674546971cec42935712bf92c72 451 SMART SM01091 355 432 2.2E-18 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_14010 6188b674546971cec42935712bf92c72 451 Gene3D G3DSA:3.10.580.10 195 349 4.4E-51 T 15-10-2018 C2I28_14010 6188b674546971cec42935712bf92c72 451 Pfam PF03471 Transporter associated domain 356 430 9.2E-14 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_14010 6188b674546971cec42935712bf92c72 451 Pfam PF01595 Domain of unknown function DUF21 7 201 4.3E-49 T 15-10-2018 IPR002550 CNNM, transmembrane domain C2I28_14010 6188b674546971cec42935712bf92c72 451 SUPERFAMILY SSF54631 204 342 1.89E-28 T 15-10-2018 C2I28_14010 6188b674546971cec42935712bf92c72 451 SUPERFAMILY SSF56176 353 430 4.64E-14 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_14010 6188b674546971cec42935712bf92c72 451 Pfam PF00571 CBS domain 293 339 5.1E-5 T 15-10-2018 IPR000644 CBS domain C2I28_14010 6188b674546971cec42935712bf92c72 451 Pfam PF00571 CBS domain 218 272 5.6E-6 T 15-10-2018 IPR000644 CBS domain C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF55874 1045 1185 1.3E-35 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF55785 854 961 7.68E-17 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF01339 CheB methylesterase 24 197 2.6E-48 T 15-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 PRINTS PR00996 Glutamate methyltransferase family signature 418 432 1.2E-24 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 PRINTS PR00996 Glutamate methyltransferase family signature 234 247 1.2E-24 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 PRINTS PR00996 Glutamate methyltransferase family signature 315 335 1.2E-24 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 PRINTS PR00996 Glutamate methyltransferase family signature 351 367 1.2E-24 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 PRINTS PR00996 Glutamate methyltransferase family signature 437 460 1.2E-24 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF55785 743 845 6.05E-5 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:3.30.450.20 715 847 3.1E-8 T 15-10-2018 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1081 1185 1.1E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF01739 CheR methyltransferase, SAM binding domain 281 475 6.6E-56 T 15-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:3.40.50.180 14 204 4.1E-58 T 15-10-2018 IPR035909 Methylesterase CheB, C-terminal C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF00512 His Kinase A (phospho-acceptor) domain 974 1035 1.4E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SMART SM00086 917 959 3.8E-5 T 15-10-2018 IPR001610 PAC motif C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:3.30.450.20 848 972 5.3E-22 T 15-10-2018 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF13596 PAS domain 731 836 2.6E-24 T 15-10-2018 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SMART SM00388 974 1037 4.6E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF03705 CheR methyltransferase, all-alpha domain 215 263 1.4E-10 T 15-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF53335 280 477 1.89E-43 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF52738 20 205 2.22E-50 T 15-10-2018 IPR035909 Methylesterase CheB, C-terminal C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:1.10.155.10 205 275 2.8E-5 T 15-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Pfam PF13426 PAS domain 856 958 2.9E-13 T 15-10-2018 IPR000014 PAS domain C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:3.40.50.150 279 480 3.3E-64 T 15-10-2018 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:1.10.287.130 977 1034 6.3E-16 T 15-10-2018 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF47384 963 1035 4.71E-14 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SMART SM00387 1079 1186 7.3E-25 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 853 965 5.1E-10 T 15-10-2018 IPR000014 PAS domain C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 Gene3D G3DSA:3.30.565.10 1038 1186 1.2E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SUPERFAMILY SSF47757 204 282 1.18E-11 T 15-10-2018 C2I28_19500 38a5f6a64dcbf9511f73f237c4cbdcb4 1186 SMART SM00138 212 478 2.7E-75 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 PIRSF PIRSF001423 1 553 1.9E-292 T 15-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 Pfam PF17392 Urocanase C-terminal domain 348 542 9.4E-96 T 15-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 Pfam PF17391 Urocanase N-terminal domain 8 134 4.8E-61 T 15-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 15-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 SUPERFAMILY SSF111326 6 551 6.15E-256 T 15-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 Gene3D G3DSA:3.40.1770.10 16 538 1.1E-252 T 15-10-2018 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 549 6.7E-299 T 15-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 Gene3D G3DSA:3.40.50.10730 138 345 1.1E-252 T 15-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 Hamap MF_00577 Urocanate hydratase [hutU]. 1 552 49.91 T 15-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16005 0831b9a9d4d2529bf18723e5e6fffbab 553 Pfam PF01175 Urocanase Rossmann-like domain 137 345 3.0E-87 T 15-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 SUPERFAMILY SSF81660 331 534 3.92E-54 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Gene3D G3DSA:3.40.50.1000 321 677 0.0 T 15-10-2018 IPR023214 HAD superfamily C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Gene3D G3DSA:1.20.1110.10 54 877 0.0 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 344 5.0E-45 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 598 722 3.2E-37 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 426 577 6.0E-19 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 SUPERFAMILY SSF81665 2 881 8.76E-131 T 15-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 664 689 1.7E-19 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 1.7E-19 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 1.7E-19 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 604 620 1.7E-19 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 2.1E-17 T 15-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 SUPERFAMILY SSF81653 115 223 8.11E-29 T 15-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 SUPERFAMILY SSF56784 322 736 1.6E-69 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 15-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 646 2.8E-29 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 1.7E-41 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 1.7E-41 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 1.7E-41 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 1.7E-41 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 1.7E-41 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 1.7E-41 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Pfam PF00689 Cation transporting ATPase, C-terminus 716 881 1.3E-51 T 15-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 SMART SM00831 2 76 3.3E-23 T 15-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Gene3D G3DSA:3.40.1110.10 334 537 0.0 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Pfam PF00122 E1-E2 ATPase 111 304 3.3E-53 T 15-10-2018 C2I28_02805 e15c217ea21ecdb3fb9c8a9f778f2666 892 Gene3D G3DSA:2.70.150.10 16 227 0.0 T 15-10-2018 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 33.097 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 3.0E-40 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 3.0E-40 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 3.0E-40 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 3.0E-40 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 3.0E-40 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 Gene3D G3DSA:3.30.1360.80 1 157 6.1E-62 T 15-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 PIRSF PIRSF006160 1 157 3.5E-61 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 152 7.1E-51 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 2.0E-73 T 15-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_05910 d64bc7911c105ac43963af2a22342769 157 SUPERFAMILY SSF63411 4 152 2.01E-59 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_08575 c8de126a05f39f571e99ae652d921205 218 PIRSF PIRSF000441 1 216 8.3E-86 T 15-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 C2I28_08575 c8de126a05f39f571e99ae652d921205 218 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 1.4E-4 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_08575 c8de126a05f39f571e99ae652d921205 218 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.8E-7 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_08575 c8de126a05f39f571e99ae652d921205 218 Gene3D G3DSA:1.10.3130.10 1 66 7.5E-26 T 15-10-2018 C2I28_08575 c8de126a05f39f571e99ae652d921205 218 Pfam PF06426 Serine acetyltransferase, N-terminal 4 35 1.3E-5 T 15-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 C2I28_08575 c8de126a05f39f571e99ae652d921205 218 SUPERFAMILY SSF51161 3 168 3.6E-57 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_08575 c8de126a05f39f571e99ae652d921205 218 Gene3D G3DSA:2.160.10.10 67 181 1.7E-36 T 15-10-2018 C2I28_08575 c8de126a05f39f571e99ae652d921205 218 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 6.7E-79 T 15-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 C2I28_07140 82129354e6064870f9994a3b1f52e18c 155 Pfam PF05130 FlgN protein 3 140 1.0E-20 T 15-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 C2I28_07140 82129354e6064870f9994a3b1f52e18c 155 Gene3D G3DSA:1.20.58.300 5 126 1.5E-5 T 15-10-2018 C2I28_07140 82129354e6064870f9994a3b1f52e18c 155 SUPERFAMILY SSF140566 3 126 3.14E-15 T 15-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 Gene3D G3DSA:1.10.10.10 131 229 2.7E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 SMART SM00448 3 113 1.4E-37 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 SUPERFAMILY SSF46894 130 226 3.68E-25 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 SUPERFAMILY SSF52172 2 126 4.27E-36 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 Pfam PF00072 Response regulator receiver domain 5 114 3.3E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 2.0E-22 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 SMART SM00862 153 227 1.1E-20 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_26095 11dbcc17c96d53d3a79cd001a0f8fb40 233 Gene3D G3DSA:3.40.50.2300 1 130 1.0E-33 T 15-10-2018 C2I28_06610 b80116cf0d37d5cebb89015761567bfd 85 Pfam PF10835 Protein of unknown function (DUF2573) 4 79 1.9E-37 T 15-10-2018 IPR020393 Uncharacterised protein family YusU C2I28_06610 b80116cf0d37d5cebb89015761567bfd 85 ProDom PD065427 YUSU IG COIL COILED BH3491 5 80 2.0E-26 T 15-10-2018 IPR020393 Uncharacterised protein family YusU C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 3.2E-102 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 4.7E-42 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 Pfam PF00303 Thymidylate synthase 2 264 4.3E-132 T 15-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 41.445 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.0E-51 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 1.0E-51 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 1.0E-51 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 1.0E-51 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 1.0E-51 T 15-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 SUPERFAMILY SSF55831 2 264 2.36E-134 T 15-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 15-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_01860 cf3dac31149f953bb7f044a6893c9dce 264 Gene3D G3DSA:3.30.572.10 1 264 5.8E-138 T 15-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Pfam PF01568 Molydopterin dinucleotide binding domain 597 702 1.0E-28 T 15-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Gene3D G3DSA:2.20.25.90 21 73 9.4E-10 T 15-10-2018 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Gene3D G3DSA:3.40.50.740 84 552 1.9E-159 T 15-10-2018 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 SUPERFAMILY SSF50692 567 708 2.71E-34 T 15-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 SMART SM00926 19 75 2.1E-8 T 15-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Gene3D G3DSA:2.40.40.20 594 709 1.1E-35 T 15-10-2018 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Gene3D G3DSA:3.40.228.10 156 355 1.9E-159 T 15-10-2018 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 20 72 7.0E-12 T 15-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 SUPERFAMILY SSF53706 19 579 1.7E-169 T 15-10-2018 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 PIRSF PIRSF000144 67 707 3.6E-39 T 15-10-2018 C2I28_12105 3e2aaf4b1a006394c5cff5a535936d60 716 Pfam PF00384 Molybdopterin oxidoreductase 78 503 2.2E-86 T 15-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 Pfam PF12840 Helix-turn-helix domain 9 67 1.2E-13 T 15-10-2018 C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 SUPERFAMILY SSF46785 9 94 6.18E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.9E-9 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.9E-9 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.9E-9 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 SMART SM00418 9 90 1.6E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_20075 ac30d95ba57ae10f4cc87e50bf645172 111 Gene3D G3DSA:1.10.10.10 2 110 7.5E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 SUPERFAMILY SSF52540 342 582 4.24E-68 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 Pfam PF00989 PAS fold 217 314 6.6E-7 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 Pfam PF00158 Sigma-54 interaction domain 343 510 2.0E-65 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 Gene3D G3DSA:3.30.450.20 203 316 1.6E-19 T 15-10-2018 C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 430 445 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 552 561 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 Gene3D G3DSA:1.10.8.60 515 589 2.8E-17 T 15-10-2018 C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 Gene3D G3DSA:3.40.50.300 331 514 1.1E-64 T 15-10-2018 C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 SMART SM00091 216 282 5.4E-5 T 15-10-2018 IPR000014 PAS domain C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 SMART SM00382 363 508 6.7E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17035 ca2b2bfaed43c5f504a2b7f2863c2f28 703 SUPERFAMILY SSF55785 227 327 5.58E-9 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 SUPERFAMILY SSF51306 29 181 4.36E-49 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 3.0E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 82 94 3.0E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 31 47 3.0E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 ProSitePatterns PS00501 Signal peptidases I serine active site. 40 47 - T 15-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 15 177 4.7E-55 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 ProSitePatterns PS00760 Signal peptidases I lysine active site. 84 96 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 Gene3D G3DSA:2.10.109.10 61 184 7.2E-37 T 15-10-2018 C2I28_23250 7b945e0fff435e671cac0a72b0d20f7d 184 Pfam PF00717 Peptidase S24-like 38 106 1.7E-20 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_25495 c2cceff41f6c92307030614523e778d3 160 Gene3D G3DSA:2.40.50.660 71 160 1.7E-13 T 15-10-2018 C2I28_25495 c2cceff41f6c92307030614523e778d3 160 Pfam PF10694 Protein of unknown function (DUF2500) 46 150 3.8E-36 T 15-10-2018 IPR019635 Protein of unknown function DUF2500 C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 SUPERFAMILY SSF52540 4 520 3.36E-29 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 Gene3D G3DSA:3.40.50.300 254 566 7.4E-53 T 15-10-2018 C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 PIRSF PIRSF003128 1 571 5.4E-188 T 15-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 2.6E-197 T 15-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 Gene3D G3DSA:3.40.50.300 1 232 3.3E-45 T 15-10-2018 C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 SUPERFAMILY SSF52540 2 218 2.0E-65 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03820 6d9607e698578c91250974bee1a41a6a 575 Pfam PF13476 AAA domain 4 220 5.9E-18 T 15-10-2018 IPR038729 Rad50/SbcC-type AAA domain C2I28_19420 77656d81a1e013fc7f084dd02eb76bfb 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 9.6E-15 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_19420 77656d81a1e013fc7f084dd02eb76bfb 129 Gene3D G3DSA:1.10.10.10 9 125 5.5E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19420 77656d81a1e013fc7f084dd02eb76bfb 129 SUPERFAMILY SSF46785 5 78 9.87E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_19420 77656d81a1e013fc7f084dd02eb76bfb 129 SMART SM00345 16 75 8.1E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 SUPERFAMILY SSF54211 236 488 2.5E-81 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 SUPERFAMILY SSF110942 510 624 3.01E-29 T 15-10-2018 IPR037196 HSP90, C-terminal domain C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 15-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 625 26.62 T 15-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 150 2.1E-12 T 15-10-2018 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Gene3D G3DSA:3.30.230.80 235 407 1.4E-55 T 15-10-2018 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Pfam PF00183 Hsp90 protein 184 228 3.8E-7 T 15-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Pfam PF00183 Hsp90 protein 224 624 1.3E-108 T 15-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 72 89 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 90 107 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 115 137 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 188 206 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 23 45 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 165 182 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PRINTS PR00775 90kDa heat shock protein signature 2 22 8.8E-55 T 15-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Gene3D G3DSA:1.20.120.790 495 625 3.1E-34 T 15-10-2018 IPR037196 HSP90, C-terminal domain C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 PIRSF PIRSF002583 1 625 4.8E-200 T 15-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Gene3D G3DSA:3.30.565.10 1 225 1.6E-73 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 SUPERFAMILY SSF55874 2 211 4.11E-62 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20125 3e4ca2d64d45162cc118bec8bf2f5fb8 625 Gene3D G3DSA:3.40.50.11260 408 494 3.1E-26 T 15-10-2018 C2I28_24000 9e14d3c2ad517b23f4dd87ac491b65a9 359 Pfam PF13367 Protease prsW family 167 332 7.7E-22 T 15-10-2018 IPR026898 Protease PrsW GO:0008233 C2I28_24000 9e14d3c2ad517b23f4dd87ac491b65a9 359 Pfam PF13240 zinc-ribbon domain 2 24 2.8E-6 T 15-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 C2I28_14165 5416ac91b95f397a6795f453089c72a3 506 PIRSF PIRSF005690 6 493 6.7E-141 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_14165 5416ac91b95f397a6795f453089c72a3 506 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 22 480 4.7E-152 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_15105 f88e1d978e3aa24e13e0eb534cbe0680 220 ProDom PD210561 YWRJ 2 220 5.0E-70 T 15-10-2018 IPR020173 Uncharacterised protein family YwrJ C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 SUPERFAMILY SSF102114 198 434 6.15E-66 T 15-10-2018 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 Pfam PF01938 TRAM domain 441 502 5.8E-15 T 15-10-2018 IPR002792 TRAM domain C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 15-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 74.67 T 15-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 Gene3D G3DSA:3.80.30.20 210 443 1.1E-92 T 15-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 Gene3D G3DSA:3.40.50.12160 66 200 3.5E-34 T 15-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 502 3.8E-212 T 15-10-2018 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 6.4E-166 T 15-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 Pfam PF00919 Uncharacterized protein family UPF0004 67 168 4.2E-29 T 15-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 SMART SM00729 211 429 6.3E-66 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_02125 da9363fab78977b65fff6bf549dbb52d 509 Pfam PF04055 Radical SAM superfamily 215 386 2.3E-36 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_06755 1df55f131c397903391161252e14f727 265 Gene3D G3DSA:3.10.20.10 28 110 5.4E-14 T 15-10-2018 C2I28_06755 1df55f131c397903391161252e14f727 265 Pfam PF02634 FdhD/NarQ family 26 261 9.4E-75 T 15-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I28_06755 1df55f131c397903391161252e14f727 265 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 21 262 6.3E-72 T 15-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I28_06755 1df55f131c397903391161252e14f727 265 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 262 31.083 T 15-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I28_06755 1df55f131c397903391161252e14f727 265 Gene3D G3DSA:3.40.140.10 116 265 8.2E-47 T 15-10-2018 C2I28_06755 1df55f131c397903391161252e14f727 265 PIRSF PIRSF015626 1 264 6.3E-75 T 15-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 C2I28_06755 1df55f131c397903391161252e14f727 265 SUPERFAMILY SSF53927 5 261 1.86E-73 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_03695 8e568c415a5feb651e84590170493684 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 96 110 5.7E-5 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_03695 8e568c415a5feb651e84590170493684 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 206 5.7E-5 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_03695 8e568c415a5feb651e84590170493684 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 148 5.7E-5 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_03695 8e568c415a5feb651e84590170493684 516 Gene3D G3DSA:3.90.226.10 262 516 1.8E-91 T 15-10-2018 C2I28_03695 8e568c415a5feb651e84590170493684 516 Pfam PF01039 Carboxyl transferase domain 29 514 8.2E-194 T 15-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 C2I28_03695 8e568c415a5feb651e84590170493684 516 SUPERFAMILY SSF52096 244 516 6.63E-90 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_03695 8e568c415a5feb651e84590170493684 516 SUPERFAMILY SSF52096 4 257 1.44E-79 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_03695 8e568c415a5feb651e84590170493684 516 Gene3D G3DSA:3.90.226.10 2 259 1.2E-94 T 15-10-2018 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 SUPERFAMILY SSF51064 131 186 1.22E-19 T 15-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 Pfam PF01025 GrpE 23 186 1.6E-54 T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 ProSitePatterns PS01071 grpE protein signature. 141 184 - T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 Gene3D G3DSA:3.90.20.20 2 129 2.0E-26 T 15-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 Gene3D G3DSA:2.30.22.10 130 186 1.8E-25 T 15-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 SUPERFAMILY SSF58014 33 130 1.96E-27 T 15-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 Hamap MF_01151 Protein GrpE [grpE]. 4 186 21.873 T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 PRINTS PR00773 GrpE protein signature 165 184 3.1E-29 T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 PRINTS PR00773 GrpE protein signature 138 153 3.1E-29 T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 PRINTS PR00773 GrpE protein signature 56 72 3.1E-29 T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_04385 73d887cbec6943f8f7508cca0f72720c 186 PRINTS PR00773 GrpE protein signature 84 99 3.1E-29 T 15-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 C2I28_14980 5c13147f5237708c14d871cb5d9dd720 375 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 373 5.3E-175 T 15-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 C2I28_14980 5c13147f5237708c14d871cb5d9dd720 375 Pfam PF00534 Glycosyl transferases group 1 190 347 9.5E-41 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_14980 5c13147f5237708c14d871cb5d9dd720 375 Pfam PF13439 Glycosyltransferase Family 4 13 177 3.5E-25 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_14980 5c13147f5237708c14d871cb5d9dd720 375 Gene3D G3DSA:3.40.50.2000 175 356 3.5E-119 T 15-10-2018 C2I28_14980 5c13147f5237708c14d871cb5d9dd720 375 Gene3D G3DSA:3.40.50.2000 22 369 3.5E-119 T 15-10-2018 C2I28_14980 5c13147f5237708c14d871cb5d9dd720 375 SUPERFAMILY SSF53756 9 373 6.67E-84 T 15-10-2018 C2I28_26880 56b68ab336c298a6e836105a088cc25b 382 Pfam PF00589 Phage integrase family 190 364 2.8E-18 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_26880 56b68ab336c298a6e836105a088cc25b 382 Gene3D G3DSA:1.10.150.130 55 185 4.7E-11 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_26880 56b68ab336c298a6e836105a088cc25b 382 SUPERFAMILY SSF56349 73 368 3.24E-37 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_26880 56b68ab336c298a6e836105a088cc25b 382 Gene3D G3DSA:1.10.443.10 187 373 1.6E-27 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_15940 30582a96976d6b42b359a83c0479ac47 233 Gene3D G3DSA:1.10.3720.10 2 229 2.9E-47 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15940 30582a96976d6b42b359a83c0479ac47 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 225 4.1E-17 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_15940 30582a96976d6b42b359a83c0479ac47 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 117 2.1E-19 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_15940 30582a96976d6b42b359a83c0479ac47 233 SUPERFAMILY SSF161098 19 210 1.57E-38 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 185 202 - T 15-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 SUPERFAMILY SSF53697 5 248 9.3E-72 T 15-10-2018 C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 Gene3D G3DSA:3.40.50.10490 1 218 2.1E-78 T 15-10-2018 C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 Pfam PF01380 SIS domain 128 210 6.1E-7 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 2 294 40.779 T 15-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 Gene3D G3DSA:1.10.8.1080 219 296 2.6E-24 T 15-10-2018 C2I28_13235 e76c3896d59cfb81e3beac63d1963be9 304 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 6 294 2.1E-115 T 15-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I28_23850 c269abdecab30bf13dcf4c1354e52fd2 274 SUPERFAMILY SSF56784 59 252 9.85E-48 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_23850 c269abdecab30bf13dcf4c1354e52fd2 274 PIRSF PIRSF019271 1 274 1.3E-105 T 15-10-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 C2I28_23850 c269abdecab30bf13dcf4c1354e52fd2 274 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 1 273 4.1E-95 T 15-10-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 C2I28_23850 c269abdecab30bf13dcf4c1354e52fd2 274 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 20 246 1.1E-51 T 15-10-2018 IPR005519 Acid phosphatase, class B-like C2I28_23850 c269abdecab30bf13dcf4c1354e52fd2 274 Gene3D G3DSA:3.40.50.1000 25 274 2.2E-93 T 15-10-2018 IPR023214 HAD superfamily C2I28_17015 2926274eeca1015523cd0bec37892c85 421 Gene3D G3DSA:2.30.40.20 28 81 8.6E-51 T 15-10-2018 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 Gene3D G3DSA:1.10.150.20 189 242 8.6E-51 T 15-10-2018 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 Gene3D G3DSA:3.30.70.270 11 245 8.6E-51 T 15-10-2018 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 Gene3D G3DSA:3.30.1490.100 258 367 2.1E-11 T 15-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 Pfam PF00817 impB/mucB/samB family 14 163 7.6E-29 T 15-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 SUPERFAMILY SSF56672 9 249 5.6E-53 T 15-10-2018 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 256 365 1.5E-15 T 15-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_17015 2926274eeca1015523cd0bec37892c85 421 SUPERFAMILY SSF100879 258 357 3.14E-14 T 15-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Gene3D G3DSA:1.10.8.60 776 867 1.3E-26 T 15-10-2018 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 340 1.3E-13 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 SMART SM00382 605 758 2.2E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11590 47b486cec45a958ba129c4659c18f023 867 SMART SM00382 203 348 5.6E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 9.9E-10 T 15-10-2018 IPR004176 Clp, N-terminal C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 3.2E-10 T 15-10-2018 IPR004176 Clp, N-terminal C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 769 3.2E-56 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 15-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Gene3D G3DSA:3.40.50.300 154 347 2.0E-74 T 15-10-2018 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 SUPERFAMILY SSF81923 4 160 1.37E-36 T 15-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 856 2.3E-24 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_11590 47b486cec45a958ba129c4659c18f023 867 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 865 0.0 T 15-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Gene3D G3DSA:1.10.1780.10 1 153 1.8E-34 T 15-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 9.5E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 9.5E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 9.5E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 9.5E-43 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 SMART SM01086 776 865 2.1E-33 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_11590 47b486cec45a958ba129c4659c18f023 867 SUPERFAMILY SSF52540 554 864 7.14E-83 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Gene3D G3DSA:3.40.50.300 558 774 9.6E-87 T 15-10-2018 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 SUPERFAMILY SSF52540 162 553 1.43E-98 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11590 47b486cec45a958ba129c4659c18f023 867 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 15-10-2018 IPR028299 ClpA/B, conserved site 2 C2I28_11590 47b486cec45a958ba129c4659c18f023 867 Gene3D G3DSA:3.40.50.300 348 552 1.5E-69 T 15-10-2018 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 428 2.2E-24 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 88 208 1.1E-18 T 15-10-2018 IPR000014 PAS domain C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 SUPERFAMILY SSF47384 214 277 3.34E-11 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 SMART SM00387 324 430 3.6E-31 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 SUPERFAMILY SSF55785 78 201 1.05E-19 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 Pfam PF08448 PAS fold 98 202 1.2E-9 T 15-10-2018 IPR013656 PAS fold-4 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 Gene3D G3DSA:3.30.450.20 78 201 9.8E-21 T 15-10-2018 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 220 279 3.4E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 Gene3D G3DSA:3.30.565.10 282 435 5.0E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 Gene3D G3DSA:1.10.287.130 204 280 1.2E-15 T 15-10-2018 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 1.6E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 427 1.6E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 1.6E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 1.6E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 SMART SM00388 218 281 7.1E-11 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 SMART SM00091 91 157 1.3E-9 T 15-10-2018 IPR000014 PAS domain C2I28_09790 2e7d305b91d88a1ea8ecc886a6eb3f81 436 SUPERFAMILY SSF55874 277 428 1.57E-37 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 SUPERFAMILY SSF49452 7 106 5.56E-25 T 15-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 PIRSF PIRSF000463 739 932 2.4 T 15-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 PIRSF PIRSF000463 243 641 5.2E-30 T 15-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 SMART SM00642 475 845 2.9E-7 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 320 922 7.0E-264 T 15-10-2018 IPR011840 Pullulanase, type I C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 SUPERFAMILY SSF51445 429 852 1.73E-120 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Pfam PF00128 Alpha amylase, catalytic domain 482 578 5.6E-8 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Pfam PF00128 Alpha amylase, catalytic domain 607 808 3.5E-7 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 SUPERFAMILY SSF49452 113 226 1.31E-20 T 15-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 SUPERFAMILY SSF81296 325 430 1.1E-20 T 15-10-2018 IPR014756 Immunoglobulin E-set C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Gene3D G3DSA:2.60.40.1180 855 944 3.1E-26 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Gene3D G3DSA:2.60.40.1110 116 223 7.0E-24 T 15-10-2018 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Gene3D G3DSA:2.60.40.1110 9 105 4.2E-27 T 15-10-2018 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 332 409 2.7E-13 T 15-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Pfam PF03714 Bacterial pullanase-associated domain 120 221 6.0E-20 T 15-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Pfam PF03714 Bacterial pullanase-associated domain 13 102 3.6E-19 T 15-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Gene3D G3DSA:3.20.20.80 431 854 1.4E-173 T 15-10-2018 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Gene3D G3DSA:2.60.40.2320 226 322 6.5E-7 T 15-10-2018 C2I28_17995 9f5ef6e87e23187379f3f2e23f0fd562 944 Gene3D G3DSA:2.60.40.10 323 430 1.4E-30 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 Pfam PF01546 Peptidase family M20/M25/M40 69 371 2.8E-34 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 SUPERFAMILY SSF55031 179 292 5.1E-32 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 Pfam PF07687 Peptidase dimerisation domain 181 269 3.9E-14 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 364 8.8E-121 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 SUPERFAMILY SSF53187 7 377 6.86E-81 T 15-10-2018 C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 Gene3D G3DSA:3.40.630.10 10 361 8.9E-138 T 15-10-2018 C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 PIRSF PIRSF005962 2 379 3.2E-124 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_14070 5455fee6b7dcc939d89e054804ec35e3 384 Gene3D G3DSA:3.30.70.360 177 291 8.9E-138 T 15-10-2018 C2I28_21520 d6a53d74494b4f077a2f86f756f9fa2b 85 Pfam PF17279 Family of unknown function (DUF5344) 2 82 5.8E-21 T 15-10-2018 C2I28_21520 d6a53d74494b4f077a2f86f756f9fa2b 85 ProDom PD061728 YWQI YWQIA COIL COILED 3 82 1.0E-16 T 15-10-2018 IPR020299 Uncharacterised protein family YwqI C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 SUPERFAMILY SSF55073 383 537 1.18E-44 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Pfam PF08448 PAS fold 26 120 4.0E-6 T 15-10-2018 IPR013656 PAS fold-4 C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Pfam PF00990 Diguanylate cyclase, GGDEF domain 378 531 2.4E-46 T 15-10-2018 IPR000160 GGDEF domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 266 374 3.4E-14 T 15-10-2018 IPR000014 PAS domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 129 250 1.2E-16 T 15-10-2018 IPR000014 PAS domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Gene3D G3DSA:3.30.450.20 7 123 4.5E-8 T 15-10-2018 C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 SUPERFAMILY SSF55785 269 364 1.93E-18 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Gene3D G3DSA:3.30.450.20 256 376 1.1E-20 T 15-10-2018 C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 SMART SM00091 258 323 0.13 T 15-10-2018 IPR000014 PAS domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 SMART SM00091 132 197 0.0023 T 15-10-2018 IPR000014 PAS domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Gene3D G3DSA:3.30.70.270 377 547 5.2E-55 T 15-10-2018 C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 SMART SM00267 367 535 8.3E-53 T 15-10-2018 IPR000160 GGDEF domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 374 533 9.6E-41 T 15-10-2018 IPR000160 GGDEF domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Gene3D G3DSA:3.30.450.20 124 249 4.9E-18 T 15-10-2018 C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Pfam PF13426 PAS domain 272 366 1.2E-12 T 15-10-2018 IPR000014 PAS domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 Pfam PF13426 PAS domain 143 243 5.2E-8 T 15-10-2018 IPR000014 PAS domain C2I28_25350 c3b8ac769b9e3960a408454e5ba0e726 551 SUPERFAMILY SSF55785 121 242 4.54E-18 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_11500 f8a0c5bff54860be10748dfa2ab0b36e 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 9.1E-61 T 15-10-2018 IPR007551 Protein of unknown function DUF520 C2I28_11500 f8a0c5bff54860be10748dfa2ab0b36e 163 SUPERFAMILY SSF89963 92 163 1.96E-25 T 15-10-2018 IPR036183 YajQ-like superfamily C2I28_11500 f8a0c5bff54860be10748dfa2ab0b36e 163 Gene3D G3DSA:3.30.70.860 6 163 4.4E-60 T 15-10-2018 IPR035571 UPF0234-like, C-terminal C2I28_11500 f8a0c5bff54860be10748dfa2ab0b36e 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.099 T 15-10-2018 IPR007551 Protein of unknown function DUF520 C2I28_11500 f8a0c5bff54860be10748dfa2ab0b36e 163 SUPERFAMILY SSF89963 6 90 3.66E-28 T 15-10-2018 IPR036183 YajQ-like superfamily C2I28_11500 f8a0c5bff54860be10748dfa2ab0b36e 163 Gene3D G3DSA:3.30.70.990 12 101 4.4E-60 T 15-10-2018 IPR035570 UPF0234, N-terminal C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SUPERFAMILY SSF47384 390 471 7.85E-20 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SMART SM00387 516 628 1.0E-42 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Gene3D G3DSA:3.30.450.20 173 210 3.0E-6 T 15-10-2018 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Gene3D G3DSA:3.30.450.20 32 172 2.5E-37 T 15-10-2018 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SMART SM00304 232 284 1.4E-11 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SUPERFAMILY SSF55785 278 396 2.44E-12 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 517 627 1.9E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Gene3D G3DSA:3.30.565.10 480 634 1.5E-49 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SMART SM00091 291 357 8.2E-7 T 15-10-2018 IPR000014 PAS domain C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Pfam PF00672 HAMP domain 233 281 3.6E-9 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SUPERFAMILY SSF55874 460 628 5.89E-50 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Gene3D G3DSA:1.10.287.130 396 475 2.8E-29 T 15-10-2018 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 567 2.6E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 581 2.6E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 612 625 2.6E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 588 606 2.6E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Pfam PF00989 PAS fold 293 395 4.5E-8 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SMART SM00388 404 471 1.4E-21 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Gene3D G3DSA:3.30.450.20 302 395 1.3E-21 T 15-10-2018 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Pfam PF00512 His Kinase A (phospho-acceptor) domain 405 470 5.5E-18 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 SUPERFAMILY SSF158472 233 281 9.68E-9 T 15-10-2018 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 Gene3D G3DSA:1.10.287.130 230 301 3.7E-9 T 15-10-2018 C2I28_07870 a46d4a9dc91238a50eea729282016477 635 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 291 403 7.3E-6 T 15-10-2018 IPR000014 PAS domain C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 226 8.2E-23 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 Gene3D G3DSA:3.30.1240.10 81 182 9.2E-83 T 15-10-2018 C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 SUPERFAMILY SSF56784 4 254 1.03E-67 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 252 4.6E-63 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 252 8.3E-63 T 15-10-2018 C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 Gene3D G3DSA:3.40.50.1000 4 249 9.2E-83 T 15-10-2018 IPR023214 HAD superfamily C2I28_14750 ce962821a560323967d0bd6f7e8af527 260 ProSitePatterns PS01229 Hypothetical cof family signature 2. 207 229 - T 15-10-2018 C2I28_18245 6e85ff7ca122dfc7e9cafd9f76ecc6e9 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 25 300 2.9E-81 T 15-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 C2I28_18245 6e85ff7ca122dfc7e9cafd9f76ecc6e9 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 79 101 - T 15-10-2018 IPR030470 UbiA prenyltransferase conserved site C2I28_18245 6e85ff7ca122dfc7e9cafd9f76ecc6e9 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 19 303 17.314 T 15-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 C2I28_18245 6e85ff7ca122dfc7e9cafd9f76ecc6e9 305 Pfam PF01040 UbiA prenyltransferase family 55 286 1.4E-52 T 15-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 C2I28_18245 6e85ff7ca122dfc7e9cafd9f76ecc6e9 305 Gene3D G3DSA:1.10.357.140 32 190 3.8E-16 T 15-10-2018 C2I28_11630 ba4134a1c8c56644f553b940150c0586 294 Gene3D G3DSA:3.40.50.720 3 283 2.2E-26 T 15-10-2018 C2I28_11630 ba4134a1c8c56644f553b940150c0586 294 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 179 1.8E-14 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_11630 ba4134a1c8c56644f553b940150c0586 294 SUPERFAMILY SSF51735 3 282 4.81E-25 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 SUPERFAMILY SSF47413 1 65 1.97E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 SUPERFAMILY SSF51182 55 176 6.68E-21 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 Pfam PF01381 Helix-turn-helix 7 61 1.9E-16 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 Gene3D G3DSA:2.60.120.10 67 175 2.9E-14 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 Gene3D G3DSA:1.10.260.40 1 66 5.3E-21 T 15-10-2018 C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 SMART SM00530 6 61 2.1E-16 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_09050 42f68c894fa9bf4b3f9818ebd2b767d2 180 Pfam PF07883 Cupin domain 124 173 1.4E-7 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 Gene3D G3DSA:3.30.450.20 16 120 4.4E-13 T 15-10-2018 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 SUPERFAMILY SSF52540 151 391 5.63E-66 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 175 188 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 Pfam PF00158 Sigma-54 interaction domain 151 319 6.0E-67 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 126 3.3E-6 T 15-10-2018 IPR000014 PAS domain C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 SMART SM00382 171 315 9.6E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 SUPERFAMILY SSF46689 403 449 1.33E-6 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 238 253 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 SMART SM00091 13 81 0.0087 T 15-10-2018 IPR000014 PAS domain C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 Pfam PF13426 PAS domain 26 120 4.8E-7 T 15-10-2018 IPR000014 PAS domain C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 Gene3D G3DSA:1.10.8.60 324 393 8.3E-20 T 15-10-2018 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 SUPERFAMILY SSF55785 6 119 1.12E-11 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 Gene3D G3DSA:1.10.10.60 394 452 3.5E-6 T 15-10-2018 C2I28_01940 430464e5d68d9e1ba2ac9b7457b965c8 456 Gene3D G3DSA:3.40.50.300 136 323 1.3E-65 T 15-10-2018 C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 SUPERFAMILY SSF50692 1 121 3.23E-50 T 15-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 Pfam PF02261 Aspartate decarboxylase 1 114 1.3E-52 T 15-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 97 8.0E-41 T 15-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 72.921 T 15-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 PIRSF PIRSF006246 1 126 2.9E-54 T 15-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 Gene3D G3DSA:2.40.40.20 1 125 3.4E-54 T 15-10-2018 C2I28_15005 2e0db4eddcaadc7d01a2a6a769cc5c39 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 4.3E-59 T 15-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 C2I28_04345 6b06da104b5af1304336f3720eb812ef 443 Gene3D G3DSA:2.40.50.140 372 441 6.7E-7 T 15-10-2018 C2I28_04345 6b06da104b5af1304336f3720eb812ef 443 SUPERFAMILY SSF52096 8 167 1.49E-23 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_04345 6b06da104b5af1304336f3720eb812ef 443 Pfam PF01972 Serine dehydrogenase proteinase 48 121 2.4E-9 T 15-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 C2I28_04345 6b06da104b5af1304336f3720eb812ef 443 Gene3D G3DSA:3.90.226.10 22 231 9.6E-48 T 15-10-2018 C2I28_04345 6b06da104b5af1304336f3720eb812ef 443 Pfam PF01957 NfeD-like C-terminal, partner-binding 285 432 1.4E-16 T 15-10-2018 IPR002810 NfeD-like, C-terminal domain C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 3.9E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 Gene3D G3DSA:3.40.50.2300 1 118 5.0E-29 T 15-10-2018 C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 Gene3D G3DSA:1.10.10.10 119 222 4.4E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 SMART SM00448 2 110 2.1E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 Pfam PF00072 Response regulator receiver domain 4 110 1.6E-20 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 SUPERFAMILY SSF52172 2 175 1.61E-30 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_18445 8f96fd26bd28472b6a4f225b4bd273cc 222 SMART SM00862 144 220 1.2E-20 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 SUPERFAMILY SSF51569 39 353 3.21E-101 T 15-10-2018 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 Gene3D G3DSA:3.20.20.70 93 355 2.8E-100 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 3.4E-123 T 15-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 Gene3D G3DSA:1.20.59.10 8 92 7.0E-28 T 15-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 Pfam PF01817 Chorismate mutase type II 10 87 3.4E-17 T 15-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 SMART SM00830 10 89 1.7E-20 T 15-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 Pfam PF00793 DAHP synthetase I family 110 350 1.3E-83 T 15-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_05645 aa0a81668300a572938500ad13a1e0ca 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 2.7E-41 T 15-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 336 64.725 T 15-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 Pfam PF00814 Glycoprotease family 27 311 1.5E-106 T 15-10-2018 IPR000905 Gcp-like domain C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 15-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 311 4.6E-109 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 Gene3D G3DSA:3.30.420.40 7 320 3.2E-123 T 15-10-2018 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 SUPERFAMILY SSF53067 6 126 3.82E-32 T 15-10-2018 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 1.9E-49 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 1.9E-49 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.9E-49 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 1.9E-49 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 1.9E-49 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 1.9E-49 T 15-10-2018 IPR017861 Kae1/TsaD family C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 Gene3D G3DSA:3.30.420.40 132 298 3.2E-123 T 15-10-2018 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 7.2E-134 T 15-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 C2I28_09305 f9a409f7c2d19e39be5cd42a7dec6a51 338 SUPERFAMILY SSF53067 105 312 3.66E-44 T 15-10-2018 C2I28_26180 28360c422c910058ef25e874c1026ce7 299 PIRSF PIRSF031982 3 299 1.1E-63 T 15-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL C2I28_26180 28360c422c910058ef25e874c1026ce7 299 Pfam PF12740 Chlorophyllase enzyme 57 166 8.3E-8 T 15-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 C2I28_26180 28360c422c910058ef25e874c1026ce7 299 SUPERFAMILY SSF53474 55 264 1.0E-31 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_26180 28360c422c910058ef25e874c1026ce7 299 Gene3D G3DSA:3.40.50.1820 33 276 4.0E-38 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_00070 28360c422c910058ef25e874c1026ce7 299 PIRSF PIRSF031982 3 299 1.1E-63 T 15-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL C2I28_00070 28360c422c910058ef25e874c1026ce7 299 Pfam PF12740 Chlorophyllase enzyme 57 166 8.3E-8 T 15-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 C2I28_00070 28360c422c910058ef25e874c1026ce7 299 SUPERFAMILY SSF53474 55 264 1.0E-31 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_00070 28360c422c910058ef25e874c1026ce7 299 Gene3D G3DSA:3.40.50.1820 33 276 4.0E-38 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_14205 3347604ec6193dfd4e4cebba3ab7276c 159 TIGRFAM TIGR02719 repress_PhaQ: poly-beta-hydroxybutyrate-responsive repressor 17 153 1.2E-85 T 15-10-2018 IPR014091 Transcriptional repressor poly-beta-hydroxybutyrate-responsive C2I28_14205 3347604ec6193dfd4e4cebba3ab7276c 159 Gene3D G3DSA:1.10.10.10 29 140 1.1E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14205 3347604ec6193dfd4e4cebba3ab7276c 159 Pfam PF03551 Transcriptional regulator PadR-like family 45 115 6.0E-20 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_14205 3347604ec6193dfd4e4cebba3ab7276c 159 SUPERFAMILY SSF46785 29 128 2.2E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 SUPERFAMILY SSF56645 3 240 6.94E-94 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 374 3.5E-54 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 215 6.4E-27 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 Gene3D G3DSA:1.10.540.10 1 120 9.4E-47 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 SUPERFAMILY SSF47203 226 376 3.38E-62 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 PIRSF PIRSF016578 4 367 1.4E-21 T 15-10-2018 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 4.0E-43 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 Gene3D G3DSA:2.40.110.10 121 232 1.1E-45 T 15-10-2018 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_07485 0ea34b5cbbb035806b5627aac10a0575 377 Gene3D G3DSA:1.20.140.10 233 377 1.5E-58 T 15-10-2018 C2I28_01760 7c866299f71eb1519d2834bd9b1439b4 282 Gene3D G3DSA:3.40.630.30 123 281 4.1E-14 T 15-10-2018 C2I28_01760 7c866299f71eb1519d2834bd9b1439b4 282 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 17 277 6.2E-86 T 15-10-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 C2I28_01760 7c866299f71eb1519d2834bd9b1439b4 282 Pfam PF00583 Acetyltransferase (GNAT) family 140 230 8.2E-7 T 15-10-2018 IPR000182 GNAT domain C2I28_01760 7c866299f71eb1519d2834bd9b1439b4 282 SUPERFAMILY SSF55729 126 278 1.33E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_14215 3621897106ba789455e07cbff85c859a 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_14215 3621897106ba789455e07cbff85c859a 247 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 7 247 2.7E-93 T 15-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 C2I28_14215 3621897106ba789455e07cbff85c859a 247 SUPERFAMILY SSF51735 5 247 1.56E-84 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14215 3621897106ba789455e07cbff85c859a 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 1.1E-4 T 15-10-2018 C2I28_14215 3621897106ba789455e07cbff85c859a 247 Pfam PF00106 short chain dehydrogenase 7 199 1.5E-65 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 Gene3D G3DSA:3.40.50.720 1 246 1.3E-87 T 15-10-2018 C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.8E-17 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.8E-17 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.8E-17 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.0E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.0E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.0E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 3.0E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14215 3621897106ba789455e07cbff85c859a 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.0E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_02425 0e97d04212352babe665b3163ef64058 289 Gene3D G3DSA:3.40.50.300 23 262 1.8E-58 T 15-10-2018 C2I28_02425 0e97d04212352babe665b3163ef64058 289 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 24 261 3.3E-23 T 15-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 C2I28_02425 0e97d04212352babe665b3163ef64058 289 SUPERFAMILY SSF52540 23 271 1.97E-49 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02425 0e97d04212352babe665b3163ef64058 289 PIRSF PIRSF003092 1 289 2.3E-85 T 15-10-2018 IPR025501 ATP binding protein MinD C2I28_07195 32ab7333e6d6d6b9d5135095367a5d41 332 Gene3D G3DSA:1.10.260.150 60 332 5.8E-89 T 15-10-2018 C2I28_07195 32ab7333e6d6d6b9d5135095367a5d41 332 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 96 245 6.6E-44 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_07195 32ab7333e6d6d6b9d5135095367a5d41 332 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 245 2.2E-48 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_03170 8cb52ee9e6276031212286108bf9ce31 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 44 57 - T 15-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_03170 8cb52ee9e6276031212286108bf9ce31 271 Gene3D G3DSA:3.20.20.70 1 265 3.1E-93 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03170 8cb52ee9e6276031212286108bf9ce31 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 10 265 34.899 T 15-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_03170 8cb52ee9e6276031212286108bf9ce31 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 5 261 2.0E-87 T 15-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_03170 8cb52ee9e6276031212286108bf9ce31 271 SUPERFAMILY SSF51366 3 237 3.58E-77 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_03170 8cb52ee9e6276031212286108bf9ce31 271 Pfam PF00290 Tryptophan synthase alpha chain 9 255 3.6E-89 T 15-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_04060 a02bbeb99a8f9643f07e6cf1933d91c4 300 SUPERFAMILY SSF53187 3 298 5.29E-53 T 15-10-2018 C2I28_04060 a02bbeb99a8f9643f07e6cf1933d91c4 300 Pfam PF00246 Zinc carboxypeptidase 30 232 2.6E-26 T 15-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 C2I28_04060 a02bbeb99a8f9643f07e6cf1933d91c4 300 Gene3D G3DSA:3.40.630.10 7 299 1.0E-49 T 15-10-2018 C2I28_04060 a02bbeb99a8f9643f07e6cf1933d91c4 300 SMART SM00631 10 286 5.5E-16 T 15-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 928 3.7E-271 T 15-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 SUPERFAMILY SSF52540 167 893 8.04E-26 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 SUPERFAMILY SSF53098 4 230 3.13E-58 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Gene3D G3DSA:3.40.50.300 724 925 5.4E-43 T 15-10-2018 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Pfam PF13307 Helicase C-terminal domain 745 910 3.7E-40 T 15-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 1 929 27.7 T 15-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Gene3D G3DSA:3.40.50.300 253 509 4.9E-40 T 15-10-2018 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Gene3D G3DSA:3.30.420.10 1 172 1.3E-48 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Pfam PF04851 Type III restriction enzyme, res subunit 253 466 2.6E-8 T 15-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 SUPERFAMILY SSF52540 742 892 1.73E-10 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 SMART SM00491 763 897 2.5E-30 T 15-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 173 5.1E-27 T 15-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 Pfam PF00929 Exonuclease 6 162 4.9E-32 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 SMART SM00479 4 171 3.9E-40 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_15010 84a7ca004cf8e8113a550cefbe636240 933 SMART SM00487 251 518 0.0032 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 SUPERFAMILY SSF52794 168 268 9.94E-38 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 3.0E-40 T 15-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 170 251 6.1E-32 T 15-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 SUPERFAMILY SSF55804 1 147 3.53E-44 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 Gene3D G3DSA:3.40.930.10 1 150 1.8E-48 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 Pfam PF02378 Phosphotransferase system, EIIC 295 564 5.5E-15 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 2.8E-40 T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 Gene3D G3DSA:3.40.50.2300 155 269 1.1E-42 T 15-10-2018 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 170 259 1.1E-17 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_18490 b1d11776be7f12d34acb5b6aa7cb0246 623 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 278 618 7.3E-136 T 15-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 SMART SM00345 20 79 4.2E-14 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 Gene3D G3DSA:3.40.640.10 98 458 1.2E-123 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 Gene3D G3DSA:1.10.10.10 4 92 2.4E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 Pfam PF00155 Aminotransferase class I and II 107 454 2.5E-15 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 SUPERFAMILY SSF53383 86 464 4.53E-82 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 7.4E-14 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 5.3E-5 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 5.3E-5 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01395 411d64bf9a331cebd336a649fe21c61d 469 SUPERFAMILY SSF46785 9 86 5.24E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 Gene3D G3DSA:3.30.565.10 197 339 4.3E-28 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 262 276 3.1E-5 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 314 3.1E-5 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 280 290 3.1E-5 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 SUPERFAMILY SSF47384 105 178 1.61E-6 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 SMART SM00387 225 336 8.6E-23 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 SUPERFAMILY SSF55874 184 332 5.76E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 Gene3D G3DSA:1.10.287.130 71 181 2.4E-6 T 15-10-2018 C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 226 332 2.6E-16 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_00925 ddbf0aef9083c440456cf4ca352b1766 344 SMART SM00388 119 181 1.1E-5 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_11550 078647f99222c9a39118e0521330c04d 411 Gene3D G3DSA:3.30.2330.10 198 282 1.1E-32 T 15-10-2018 C2I28_11550 078647f99222c9a39118e0521330c04d 411 Gene3D G3DSA:3.10.20.340 283 411 3.7E-51 T 15-10-2018 C2I28_11550 078647f99222c9a39118e0521330c04d 411 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 411 145.847 T 15-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I28_11550 078647f99222c9a39118e0521330c04d 411 SUPERFAMILY SSF56266 22 407 1.96E-139 T 15-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I28_11550 078647f99222c9a39118e0521330c04d 411 Pfam PF01960 ArgJ family 27 411 5.7E-152 T 15-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I28_11550 078647f99222c9a39118e0521330c04d 411 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 38 411 7.0E-159 T 15-10-2018 C2I28_11550 078647f99222c9a39118e0521330c04d 411 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 17 411 1.1E-161 T 15-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I28_11550 078647f99222c9a39118e0521330c04d 411 Gene3D G3DSA:3.60.70.12 7 197 1.6E-70 T 15-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 C2I28_27000 76c430fe5d4a733de22de40372a05897 163 SUPERFAMILY SSF48371 10 120 2.64E-12 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_27000 76c430fe5d4a733de22de40372a05897 163 Gene3D G3DSA:1.25.10.10 2 152 2.0E-13 T 15-10-2018 IPR011989 Armadillo-like helical C2I28_27000 76c430fe5d4a733de22de40372a05897 163 Pfam PF13646 HEAT repeats 4 77 1.6E-10 T 15-10-2018 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 44 59 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 Pfam PF00375 Sodium:dicarboxylate symporter family 17 410 4.8E-101 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 SUPERFAMILY SSF118215 17 411 4.58E-107 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 Gene3D G3DSA:1.10.3860.10 7 425 6.1E-113 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 PRINTS PR00173 Glutamate-aspartate symporter signature 301 327 1.6E-18 T 15-10-2018 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 1.6E-18 T 15-10-2018 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 1.6E-18 T 15-10-2018 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 PRINTS PR00173 Glutamate-aspartate symporter signature 153 175 1.6E-18 T 15-10-2018 C2I28_01260 3b4dacb28321bf8ceb72da6422b99859 450 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 304 327 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Gene3D G3DSA:1.10.10.10 85 158 7.4E-6 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Gene3D G3DSA:1.10.10.10 1 68 2.2E-9 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 SUPERFAMILY SSF46785 96 140 5.45E-5 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Gene3D G3DSA:1.10.1790.10 194 290 2.7E-13 T 15-10-2018 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Pfam PF08279 HTH domain 21 65 1.1E-6 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 SUPERFAMILY SSF63520 181 288 1.27E-17 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Gene3D G3DSA:1.10.1790.10 306 407 9.5E-24 T 15-10-2018 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 509 646 5.1E-31 T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 SUPERFAMILY SSF63520 307 406 6.02E-24 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Gene3D G3DSA:3.40.50.2300 416 501 3.1E-8 T 15-10-2018 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Pfam PF00874 PRD domain 317 405 1.7E-22 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Pfam PF00874 PRD domain 209 288 3.9E-17 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 SUPERFAMILY SSF55804 508 646 9.94E-32 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 SUPERFAMILY SSF52794 415 495 6.28E-5 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Gene3D G3DSA:3.40.930.10 505 647 1.8E-28 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_12030 fcadf590d4a4abca444319bc0910eba2 649 Pfam PF05043 Mga helix-turn-helix domain 84 173 2.8E-15 T 15-10-2018 IPR007737 Mga helix-turn-helix domain C2I28_18850 0b7273d894d6aae1fa7423a896b56b25 387 Gene3D G3DSA:3.40.50.2000 170 354 2.6E-73 T 15-10-2018 C2I28_18850 0b7273d894d6aae1fa7423a896b56b25 387 SUPERFAMILY SSF53756 18 367 2.87E-72 T 15-10-2018 C2I28_18850 0b7273d894d6aae1fa7423a896b56b25 387 Gene3D G3DSA:3.40.50.2000 26 367 2.6E-73 T 15-10-2018 C2I28_18850 0b7273d894d6aae1fa7423a896b56b25 387 Pfam PF00534 Glycosyl transferases group 1 187 349 3.1E-37 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_18850 0b7273d894d6aae1fa7423a896b56b25 387 Pfam PF13477 Glycosyl transferase 4-like 5 146 7.4E-16 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_14295 868e88442368d76086a6c9905109e016 390 Gene3D G3DSA:3.90.1150.10 30 384 8.2E-120 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_14295 868e88442368d76086a6c9905109e016 390 Pfam PF00155 Aminotransferase class I and II 34 384 7.1E-73 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_14295 868e88442368d76086a6c9905109e016 390 SUPERFAMILY SSF53383 7 387 5.98E-109 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_14295 868e88442368d76086a6c9905109e016 390 Gene3D G3DSA:3.40.640.10 45 286 8.2E-120 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_15395 9b6010bac900a43c3a36df38dcc59e10 312 Gene3D G3DSA:1.10.3720.10 99 312 1.0E-20 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15395 9b6010bac900a43c3a36df38dcc59e10 312 SUPERFAMILY SSF161098 104 311 1.44E-26 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15395 9b6010bac900a43c3a36df38dcc59e10 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 312 2.8E-31 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_15395 9b6010bac900a43c3a36df38dcc59e10 312 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 34 86 1.2E-19 T 15-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 Pfam PF01668 SmpB protein 9 150 3.9E-63 T 15-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 2.5E-59 T 15-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 SUPERFAMILY SSF74982 4 132 4.71E-54 T 15-10-2018 IPR023620 Small protein B C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 114 3.0E-50 T 15-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 Gene3D G3DSA:2.40.280.10 3 129 9.4E-52 T 15-10-2018 IPR023620 Small protein B C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 15-10-2018 IPR020081 SsrA-binding protein, conserved site C2I28_06790 ff2935e66b35d8fa34822daf9285180c 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 78.24 T 15-10-2018 IPR000037 SsrA-binding protein GO:0003723 C2I28_13685 49e6fd9e3595a8c1da529a08f22ff1e5 421 Gene3D G3DSA:3.40.50.2000 225 406 7.5E-17 T 15-10-2018 C2I28_13685 49e6fd9e3595a8c1da529a08f22ff1e5 421 Pfam PF13692 Glycosyl transferases group 1 248 385 2.8E-19 T 15-10-2018 C2I28_13685 49e6fd9e3595a8c1da529a08f22ff1e5 421 SUPERFAMILY SSF53756 3 420 7.53E-22 T 15-10-2018 C2I28_08890 adf8a9babdf093e748b31718671778a3 254 Gene3D G3DSA:3.20.20.370 48 254 4.4E-51 T 15-10-2018 C2I28_08890 adf8a9babdf093e748b31718671778a3 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 1.2E-73 T 15-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB C2I28_08890 adf8a9babdf093e748b31718671778a3 254 SUPERFAMILY SSF88713 16 242 2.22E-47 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_08890 adf8a9babdf093e748b31718671778a3 254 Pfam PF01522 Polysaccharide deacetylase 55 175 4.7E-21 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 445 2.6E-22 T 15-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 512 553 2.7E-11 T 15-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 SUPERFAMILY SSF53738 304 455 6.28E-32 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 179 2.0E-43 T 15-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 SUPERFAMILY SSF53738 209 316 1.59E-19 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Gene3D G3DSA:3.30.310.50 488 569 4.2E-8 T 15-10-2018 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 SUPERFAMILY SSF55957 445 573 3.53E-13 T 15-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Gene3D G3DSA:3.40.120.10 31 189 5.4E-48 T 15-10-2018 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Gene3D G3DSA:3.40.120.10 325 452 1.1E-36 T 15-10-2018 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 226 315 8.2E-23 T 15-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 15-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 1.3E-5 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 137 151 1.3E-5 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 Gene3D G3DSA:3.40.120.10 200 324 9.5E-22 T 15-10-2018 C2I28_13725 4c7f12c8c4039f85eae72c09a6cdd477 580 SUPERFAMILY SSF53738 27 236 1.1E-46 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 168 5.2E-55 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 SUPERFAMILY SSF52467 153 323 2.12E-34 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 15-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 Gene3D G3DSA:3.40.50.1220 182 325 3.1E-37 T 15-10-2018 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 Gene3D G3DSA:3.40.50.970 1 176 2.3E-63 T 15-10-2018 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 318 6.4E-32 T 15-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 SUPERFAMILY SSF52518 357 529 1.81E-46 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 Gene3D G3DSA:3.40.50.970 355 531 6.0E-49 T 15-10-2018 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 527 1.3E-33 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_16565 74f0a1f9b22cad776dead4f8028cc6e1 531 SUPERFAMILY SSF52518 1 179 5.42E-52 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_22810 bfac8a692e299dd280d032ebc04cebe3 141 SUPERFAMILY SSF49764 47 138 6.28E-20 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_22810 bfac8a692e299dd280d032ebc04cebe3 141 Gene3D G3DSA:2.60.40.790 11 140 1.0E-19 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_22810 bfac8a692e299dd280d032ebc04cebe3 141 Pfam PF00011 Hsp20/alpha crystallin family 60 138 1.0E-11 T 15-10-2018 IPR002068 Alpha crystallin/Hsp20 domain C2I28_12470 ee65bfe12b5f2a45bc70fc6dcd18ade4 372 Pfam PF05145 Transition state regulatory protein AbrB 33 358 4.6E-83 T 15-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 C2I28_12470 ee65bfe12b5f2a45bc70fc6dcd18ade4 372 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 198 358 3.9E-35 T 15-10-2018 IPR017516 AbrB duplication C2I28_12470 ee65bfe12b5f2a45bc70fc6dcd18ade4 372 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 12 171 5.8E-37 T 15-10-2018 IPR017516 AbrB duplication C2I28_12470 ee65bfe12b5f2a45bc70fc6dcd18ade4 372 PIRSF PIRSF038991 1 367 3.2E-88 T 15-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 Gene3D G3DSA:3.40.50.300 53 263 3.1E-33 T 15-10-2018 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 SMART SM00382 89 267 4.2E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 SUPERFAMILY SSF52540 55 328 7.61E-45 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 2.0E-32 T 15-10-2018 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 2.0E-32 T 15-10-2018 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 2.0E-32 T 15-10-2018 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 2.0E-32 T 15-10-2018 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 2.0E-32 T 15-10-2018 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 15-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 533 2.6E-277 T 15-10-2018 IPR014251 Sporulation protease LonB C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 Gene3D G3DSA:3.30.230.10 345 545 9.1E-51 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 173 188 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 266 3.0E-19 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 SUPERFAMILY SSF54211 350 532 1.56E-41 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_05000 c79b0b9a6da55d797dab0e4bf6de7815 555 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 345 534 7.9E-36 T 15-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 SUPERFAMILY SSF52922 188 325 2.49E-40 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 SUPERFAMILY SSF52518 2 204 5.4E-74 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.0E-41 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 Gene3D G3DSA:3.40.50.920 193 327 1.6E-42 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 Gene3D G3DSA:3.40.50.970 1 192 1.3E-93 T 15-10-2018 C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 9.7E-53 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_03755 8d40eafaae30a7c3730b3df28e0cd563 327 SMART SM00861 4 179 3.0E-72 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_09590 f906af2776426fe3906d882f82047b60 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.0E-92 T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 8.3E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 8.3E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 8.3E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 8.3E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 SUPERFAMILY SSF55920 1 247 1.57E-86 T 15-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I28_09590 f906af2776426fe3906d882f82047b60 248 Pfam PF00557 Metallopeptidase family M24 12 239 2.0E-53 T 15-10-2018 IPR000994 Peptidase M24 C2I28_09590 f906af2776426fe3906d882f82047b60 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 39.094 T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_09590 f906af2776426fe3906d882f82047b60 248 Gene3D G3DSA:3.90.230.10 1 248 1.8E-107 T 15-10-2018 C2I28_25295 1c18c9383e336e5dd785b33f40c304a8 50 Pfam PF09388 Spo0E like sporulation regulatory protein 4 44 2.3E-11 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_25295 1c18c9383e336e5dd785b33f40c304a8 50 Gene3D G3DSA:1.20.58.990 1 50 8.0E-9 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_25295 1c18c9383e336e5dd785b33f40c304a8 50 SUPERFAMILY SSF140500 2 47 2.49E-11 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_14185 9fa1da85c413271faaff358a6c86b151 271 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 249 1.3E-92 T 15-10-2018 IPR022493 Integral membrane YkoY C2I28_14185 9fa1da85c413271faaff358a6c86b151 271 Pfam PF03741 Integral membrane protein TerC family 15 207 2.6E-51 T 15-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I28_14185 9fa1da85c413271faaff358a6c86b151 271 SUPERFAMILY SSF103473 11 245 7.32E-7 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_14185 9fa1da85c413271faaff358a6c86b151 271 Gene3D G3DSA:1.20.1250.20 4 250 2.0E-6 T 15-10-2018 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 7.9E-15 T 15-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 6.3E-16 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 6.3E-16 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 6.3E-16 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 6.3E-16 T 15-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 Gene3D G3DSA:2.40.50.140 2 100 1.5E-24 T 15-10-2018 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.48 T 15-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 SUPERFAMILY SSF50249 9 102 7.5E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 429 8.6E-168 T 15-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 SUPERFAMILY SSF55681 110 424 6.43E-100 T 15-10-2018 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 9.9E-86 T 15-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_15035 f0a13f1aceff0a4b9f3011ddea4e2c14 430 Gene3D G3DSA:3.30.930.10 101 430 1.1E-119 T 15-10-2018 C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 Gene3D G3DSA:3.50.50.60 9 459 5.0E-142 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 Gene3D G3DSA:1.10.3110.10 110 203 5.0E-142 T 15-10-2018 C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 Gene3D G3DSA:3.90.660.20 44 416 5.0E-142 T 15-10-2018 C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 471 1.0E-131 T 15-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 Pfam PF01593 Flavin containing amine oxidoreductase 15 464 5.4E-62 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 SUPERFAMILY SSF51905 6 464 2.85E-47 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11165 c5801b5478d71cfdb2794983e34c6668 473 SUPERFAMILY SSF54373 309 417 1.23E-27 T 15-10-2018 C2I28_08255 889d20c9b1512053d971e725e37e5640 208 Gene3D G3DSA:3.40.50.300 1 208 4.2E-67 T 15-10-2018 C2I28_08255 889d20c9b1512053d971e725e37e5640 208 Pfam PF02223 Thymidylate kinase 8 198 7.2E-54 T 15-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 C2I28_08255 889d20c9b1512053d971e725e37e5640 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 197 7.2E-61 T 15-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I28_08255 889d20c9b1512053d971e725e37e5640 208 SUPERFAMILY SSF52540 1 207 3.29E-55 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08255 889d20c9b1512053d971e725e37e5640 208 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 30.952 T 15-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I28_08255 889d20c9b1512053d971e725e37e5640 208 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 15-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 Gene3D G3DSA:3.40.50.720 1 237 1.0E-60 T 15-10-2018 C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.8E-31 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.8E-31 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.8E-31 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 1.8E-31 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.8E-31 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.8E-31 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 SUPERFAMILY SSF51735 2 238 2.15E-61 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 6.4E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 6.4E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 6.4E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18760 7e02c742bf82fdf7119a312a1fc69d3b 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 235 4.8E-49 T 15-10-2018 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Pfam PF00310 Glutamine amidotransferases class-II 22 438 1.1E-188 T 15-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Pfam PF04898 Glutamate synthase central domain 463 740 1.6E-115 T 15-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Gene3D G3DSA:2.160.20.60 1215 1488 3.3E-109 T 15-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Gene3D G3DSA:3.20.20.70 443 797 0.0 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Gene3D G3DSA:3.20.20.70 489 1182 0.0 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Gene3D G3DSA:3.60.20.10 22 551 0.0 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 SUPERFAMILY SSF69336 1213 1479 6.67E-91 T 15-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 SUPERFAMILY SSF56235 22 441 2.46E-155 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 SUPERFAMILY SSF51395 454 1202 7.33E-257 T 15-10-2018 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Pfam PF01493 GXGXG motif 1244 1432 5.8E-81 T 15-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 C2I28_18295 f5180b7c85215c71f9bc1e2e6ee72ae1 1517 Pfam PF01645 Conserved region in glutamate synthase 798 1165 2.6E-159 T 15-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 3.8E-165 T 15-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 Pfam PF00549 CoA-ligase 262 380 3.3E-25 T 15-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 PIRSF PIRSF001554 1 386 1.2E-157 T 15-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 Gene3D G3DSA:3.30.470.20 1 234 2.5E-98 T 15-10-2018 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.966 T 15-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 Gene3D G3DSA:3.30.1490.20 21 104 2.5E-98 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 SUPERFAMILY SSF52210 241 386 2.49E-53 T 15-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 15-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 Pfam PF08442 ATP-grasp domain 2 203 5.9E-83 T 15-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 Gene3D G3DSA:3.40.50.261 240 386 9.6E-56 T 15-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02590 b893a190f35c35add13c9e151dab078f 386 SUPERFAMILY SSF56059 1 238 1.56E-85 T 15-10-2018 C2I28_20725 1959f3d503b82f6e67bd673195288f28 308 Pfam PF12705 PD-(D/E)XK nuclease superfamily 11 306 8.3E-10 T 15-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type C2I28_14600 64c4f10f56de84ec0b8f5c09cae6f8d3 387 Gene3D G3DSA:3.40.640.10 58 280 1.6E-127 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_14600 64c4f10f56de84ec0b8f5c09cae6f8d3 387 SUPERFAMILY SSF53383 4 381 5.11E-109 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_14600 64c4f10f56de84ec0b8f5c09cae6f8d3 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 15-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I28_14600 64c4f10f56de84ec0b8f5c09cae6f8d3 387 Pfam PF00155 Aminotransferase class I and II 29 377 9.6E-65 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_14600 64c4f10f56de84ec0b8f5c09cae6f8d3 387 Gene3D G3DSA:3.90.1150.10 29 377 1.6E-127 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_05405 17c589c41d41df063054d656fed86711 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 6.4E-133 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 PRINTS PR00143 Citrate synthase signature 123 136 1.1E-42 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 PRINTS PR00143 Citrate synthase signature 304 320 1.1E-42 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 PRINTS PR00143 Citrate synthase signature 324 338 1.1E-42 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 PRINTS PR00143 Citrate synthase signature 172 187 1.1E-42 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 PRINTS PR00143 Citrate synthase signature 247 267 1.1E-42 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 PRINTS PR00143 Citrate synthase signature 194 222 1.1E-42 T 15-10-2018 IPR002020 Citrate synthase GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 15-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I28_05405 17c589c41d41df063054d656fed86711 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 2.6E-165 T 15-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 C2I28_05405 17c589c41d41df063054d656fed86711 372 Gene3D G3DSA:1.10.580.10 25 351 3.2E-131 T 15-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 C2I28_05405 17c589c41d41df063054d656fed86711 372 PIRSF PIRSF001369 1 372 3.3E-158 T 15-10-2018 IPR024176 Citrate synthase, bacterial-type C2I28_05405 17c589c41d41df063054d656fed86711 372 Gene3D G3DSA:1.10.230.10 220 318 3.2E-131 T 15-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain C2I28_05405 17c589c41d41df063054d656fed86711 372 SUPERFAMILY SSF48256 2 371 6.15E-139 T 15-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 SUPERFAMILY SSF75217 72 248 1.0E-55 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 SUPERFAMILY SSF88697 1 68 1.81E-15 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 6 249 3.4E-73 T 15-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 Gene3D G3DSA:3.40.1280.10 72 250 8.8E-68 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 PIRSF PIRSF015601 1 249 1.3E-69 T 15-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 Gene3D G3DSA:2.40.240.20 1 71 2.7E-23 T 15-10-2018 C2I28_04365 cc33925898854a6f9a33fab66d3e5d94 250 Pfam PF04452 RNA methyltransferase 17 244 2.3E-76 T 15-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 C2I28_05875 1fafa2acf4c370a684361ceef32dd736 332 Gene3D G3DSA:3.40.190.10 142 331 1.5E-37 T 15-10-2018 C2I28_05875 1fafa2acf4c370a684361ceef32dd736 332 Gene3D G3DSA:3.40.190.10 26 126 1.8E-14 T 15-10-2018 C2I28_05875 1fafa2acf4c370a684361ceef32dd736 332 Pfam PF13379 NMT1-like family 40 262 2.5E-26 T 15-10-2018 C2I28_05875 1fafa2acf4c370a684361ceef32dd736 332 SUPERFAMILY SSF53850 31 255 2.6E-38 T 15-10-2018 C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 SUPERFAMILY SSF51735 134 303 3.47E-37 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 Pfam PF00107 Zinc-binding dehydrogenase 169 291 9.8E-26 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 Gene3D G3DSA:3.90.180.10 21 319 1.5E-85 T 15-10-2018 C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 SMART SM00829 10 326 2.2E-12 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 SUPERFAMILY SSF50129 1 162 1.73E-30 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 124 3.1E-12 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_10745 03fb6952f80bc2ccdc564ab92e231845 330 Gene3D G3DSA:3.40.50.720 139 276 1.5E-85 T 15-10-2018 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Gene3D G3DSA:3.40.50.720 3 90 7.4E-20 T 15-10-2018 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Pfam PF08245 Mur ligase middle domain 107 276 1.1E-24 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 SUPERFAMILY SSF51984 4 82 1.16E-18 T 15-10-2018 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Gene3D G3DSA:3.40.1190.10 92 292 4.1E-51 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 32.922 T 15-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 424 3.1E-131 T 15-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 SUPERFAMILY SSF53623 88 293 1.31E-56 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Gene3D G3DSA:3.90.190.20 293 432 2.9E-40 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 SUPERFAMILY SSF53244 295 425 4.21E-36 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Pfam PF01225 Mur ligase family, catalytic domain 4 102 2.2E-21 T 15-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I28_05670 679b9f31f0065cf2750a5e8e62f1ac50 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 296 377 3.4E-19 T 15-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 316 40.6 T 15-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 Gene3D G3DSA:3.40.50.450 2 285 2.4E-107 T 15-10-2018 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 SUPERFAMILY SSF53784 1 303 1.1E-103 T 15-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 Gene3D G3DSA:3.40.50.460 141 250 2.4E-107 T 15-10-2018 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 30 43 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 92 108 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 155 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 238 260 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 157 173 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 175 192 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 119 136 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 5.1E-68 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 PIRSF PIRSF000532 1 316 1.8E-111 T 15-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 Pfam PF00365 Phosphofructokinase 2 274 2.4E-100 T 15-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_16200 b990c7e07cc7d7bb016f863f68fd6a8b 317 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 2 298 1.1E-119 T 15-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 Gene3D G3DSA:1.10.1520.10 15 169 2.8E-47 T 15-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 SMART SM00535 35 170 1.4E-58 T 15-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 23 242 4.7E-79 T 15-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 ProSitePatterns PS00517 Ribonuclease III family signature. 59 67 - T 15-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 Hamap MF_00104 Ribonuclease 3 [rnc]. 23 239 31.449 T 15-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 SMART SM00358 176 243 1.5E-21 T 15-10-2018 IPR014720 Double-stranded RNA-binding domain C2I28_02660 89acc470f92bb58be09c257c054143bf 248 SUPERFAMILY SSF69065 12 177 1.92E-52 T 15-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 Pfam PF00035 Double-stranded RNA binding motif 177 241 2.3E-16 T 15-10-2018 IPR014720 Double-stranded RNA-binding domain C2I28_02660 89acc470f92bb58be09c257c054143bf 248 Pfam PF14622 Ribonuclease-III-like 33 163 2.1E-36 T 15-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 SUPERFAMILY SSF54768 132 242 1.02E-23 T 15-10-2018 C2I28_02660 89acc470f92bb58be09c257c054143bf 248 Gene3D G3DSA:3.30.160.20 175 241 1.9E-21 T 15-10-2018 C2I28_02570 d04883888a275e393c7308b631710a4a 434 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 433 1.7E-239 T 15-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 C2I28_02570 d04883888a275e393c7308b631710a4a 434 Pfam PF01134 Glucose inhibited division protein A 6 367 1.0E-115 T 15-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 C2I28_02570 d04883888a275e393c7308b631710a4a 434 Gene3D G3DSA:3.50.50.60 290 434 8.4E-54 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_02570 d04883888a275e393c7308b631710a4a 434 Gene3D G3DSA:3.50.50.60 3 178 2.5E-56 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_02570 d04883888a275e393c7308b631710a4a 434 SUPERFAMILY SSF51905 8 367 2.31E-28 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_02570 d04883888a275e393c7308b631710a4a 434 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 37.129 T 15-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 C2I28_02570 d04883888a275e393c7308b631710a4a 434 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 15-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 Gene3D G3DSA:3.50.30.80 437 587 2.2E-38 T 15-10-2018 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 Pfam PF00920 Dehydratase family 86 581 2.9E-116 T 15-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 SUPERFAMILY SSF143975 84 409 4.45E-90 T 15-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 529 540 - T 15-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 SUPERFAMILY SSF52016 440 638 2.28E-37 T 15-10-2018 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 162 172 - T 15-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 C2I28_25725 5f189e0eef36a3ece8ce535eb90f1830 662 TIGRFAM TIGR03432 yjhG_yagF: putative dehydratase, YjhG/YagF family 8 646 0.0 T 15-10-2018 IPR017798 D-xylonate dehydratase YjhG/YagF GO:0050401 KEGG: 00040+4.2.1.82|MetaCyc: PWY-6760|MetaCyc: PWY-7178|MetaCyc: PWY-7294 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Gene3D G3DSA:3.40.50.10050 418 525 1.4E-39 T 15-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 622 16.988 T 15-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Gene3D G3DSA:2.40.30.10 526 622 3.3E-34 T 15-10-2018 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 SUPERFAMILY SSF52156 403 531 7.45E-39 T 15-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 SUPERFAMILY SSF50447 526 621 3.33E-33 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Pfam PF00009 Elongation factor Tu GTP binding domain 129 284 8.5E-35 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 127 283 6.2E-37 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 40 620 3.1E-278 T 15-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 ProSitePatterns PS01176 Initiation factor 2 signature. 575 597 - T 15-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 SUPERFAMILY SSF52540 117 297 6.8E-52 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 50 98 7.2E-17 T 15-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 SUPERFAMILY SSF50447 296 379 3.77E-26 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Gene3D G3DSA:3.40.50.300 121 295 5.2E-74 T 15-10-2018 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Pfam PF11987 Translation-initiation factor 2 410 514 2.1E-37 T 15-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 C2I28_02320 af2d63a89b3397e91253d943d46d2469 623 Gene3D G3DSA:2.40.30.10 296 413 1.0E-41 T 15-10-2018 C2I28_26645 10100b5de7f71d777589ee3da586fd02 187 Gene3D G3DSA:1.25.40.10 35 185 5.5E-9 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_26645 10100b5de7f71d777589ee3da586fd02 187 SUPERFAMILY SSF48452 64 172 6.64E-8 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_14470 8d874692e46207b100a36753b4e43f84 119 PIRSF PIRSF034303 1 119 4.5E-32 T 15-10-2018 IPR012543 Protein of unknown function DUF1694 C2I28_14470 8d874692e46207b100a36753b4e43f84 119 Pfam PF07997 Protein of unknown function (DUF1694) 3 108 9.8E-30 T 15-10-2018 IPR012543 Protein of unknown function DUF1694 C2I28_14470 8d874692e46207b100a36753b4e43f84 119 SUPERFAMILY SSF160515 3 109 1.44E-28 T 15-10-2018 C2I28_14470 8d874692e46207b100a36753b4e43f84 119 Gene3D G3DSA:3.30.1330.30 1 119 3.5E-34 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_15790 0009c9077c901d8da3f30b7e6300ae95 396 Gene3D G3DSA:3.90.1150.10 38 387 4.5E-139 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_15790 0009c9077c901d8da3f30b7e6300ae95 396 SUPERFAMILY SSF53383 8 394 2.86E-111 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_15790 0009c9077c901d8da3f30b7e6300ae95 396 Pfam PF00155 Aminotransferase class I and II 43 384 4.6E-66 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_15790 0009c9077c901d8da3f30b7e6300ae95 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 15-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I28_15790 0009c9077c901d8da3f30b7e6300ae95 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 1.9E-189 T 15-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type C2I28_15790 0009c9077c901d8da3f30b7e6300ae95 396 Gene3D G3DSA:3.40.640.10 58 294 4.5E-139 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_14240 d23893bc997146148ba1486086535c59 506 Gene3D G3DSA:3.20.20.70 153 329 3.0E-190 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_14240 d23893bc997146148ba1486086535c59 506 SUPERFAMILY SSF54675 6 138 7.06E-45 T 15-10-2018 C2I28_14240 d23893bc997146148ba1486086535c59 506 PIRSF PIRSF000484 3 498 2.4E-140 T 15-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I28_14240 d23893bc997146148ba1486086535c59 506 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 467 5.1E-168 T 15-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 C2I28_14240 d23893bc997146148ba1486086535c59 506 SUPERFAMILY SSF51690 141 496 8.39E-125 T 15-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 C2I28_14240 d23893bc997146148ba1486086535c59 506 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 165 346 1.4E-8 T 15-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I28_14240 d23893bc997146148ba1486086535c59 506 Gene3D G3DSA:3.20.140.10 12 488 3.0E-190 T 15-10-2018 C2I28_23015 31dbcebc616b2bdec28e90ca1c49b0f1 305 Pfam PF00892 EamA-like transporter family 154 284 1.9E-16 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_23015 31dbcebc616b2bdec28e90ca1c49b0f1 305 Pfam PF00892 EamA-like transporter family 9 139 4.9E-13 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_23015 31dbcebc616b2bdec28e90ca1c49b0f1 305 SUPERFAMILY SSF103481 195 285 5.36E-11 T 15-10-2018 C2I28_23015 31dbcebc616b2bdec28e90ca1c49b0f1 305 SUPERFAMILY SSF103481 45 142 1.24E-9 T 15-10-2018 C2I28_03300 cc647514ee63bffe8353e7b45c429e3b 224 Gene3D G3DSA:3.40.50.300 1 223 2.5E-85 T 15-10-2018 C2I28_03300 cc647514ee63bffe8353e7b45c429e3b 224 SUPERFAMILY SSF52540 5 220 3.33E-47 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03300 cc647514ee63bffe8353e7b45c429e3b 224 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 33.596 T 15-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 C2I28_03300 cc647514ee63bffe8353e7b45c429e3b 224 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 217 5.3E-87 T 15-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 C2I28_03300 cc647514ee63bffe8353e7b45c429e3b 224 Pfam PF02224 Cytidylate kinase 7 219 1.0E-79 T 15-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 C2I28_09895 e48db032f09d44e21119a889a8273b92 149 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 15-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site C2I28_09895 e48db032f09d44e21119a889a8273b92 149 Pfam PF02082 Transcriptional regulator 1 82 3.9E-26 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_09895 e48db032f09d44e21119a889a8273b92 149 SUPERFAMILY SSF46785 2 136 4.78E-39 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_09895 e48db032f09d44e21119a889a8273b92 149 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 8.6E-40 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_09895 e48db032f09d44e21119a889a8273b92 149 Gene3D G3DSA:1.10.10.10 1 142 7.0E-42 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.341 T 15-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Gene3D G3DSA:3.40.50.300 171 350 2.3E-54 T 15-10-2018 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 339 3.4E-25 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 125 1.2E-22 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Pfam PF01926 50S ribosome-binding GTPase 179 295 3.5E-26 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 7.7E-26 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 SUPERFAMILY SSF52540 138 433 1.8E-72 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 1.9E-5 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 1.9E-5 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 PIRSF PIRSF006485 2 436 4.5E-174 T 15-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Gene3D G3DSA:3.40.50.300 1 163 1.9E-46 T 15-10-2018 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 1.5E-179 T 15-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Gene3D G3DSA:3.30.300.20 353 436 6.8E-37 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 5.5E-36 T 15-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like C2I28_03265 9b668ed7a9678105f4550578ae6ab0a0 436 SUPERFAMILY SSF52540 4 166 3.58E-45 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 523 9.3E-19 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 Pfam PF00501 AMP-binding enzyme 31 439 1.9E-109 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 Gene3D G3DSA:2.30.38.10 354 432 2.3E-126 T 15-10-2018 C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 Gene3D G3DSA:3.40.50.980 52 205 2.3E-126 T 15-10-2018 C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 SUPERFAMILY SSF56801 15 534 4.06E-155 T 15-10-2018 C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 Gene3D G3DSA:3.30.300.310 435 537 7.2E-33 T 15-10-2018 C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 Gene3D G3DSA:3.40.50.980 49 353 2.3E-126 T 15-10-2018 C2I28_19835 91ae88fc38ace170bf607620f395bf7f 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_23005 fd253317ea3edf84f766182d5316139a 596 Gene3D G3DSA:1.10.3810.10 61 247 2.8E-191 T 15-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_23005 fd253317ea3edf84f766182d5316139a 596 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 62 595 1.4E-179 T 15-10-2018 C2I28_23005 fd253317ea3edf84f766182d5316139a 596 Gene3D G3DSA:3.90.1310.20 45 503 2.8E-191 T 15-10-2018 C2I28_23005 fd253317ea3edf84f766182d5316139a 596 SUPERFAMILY SSF53955 41 247 3.37E-76 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_23005 fd253317ea3edf84f766182d5316139a 596 SUPERFAMILY SSF56601 207 595 4.18E-103 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_23005 fd253317ea3edf84f766182d5316139a 596 Pfam PF00912 Transglycosylase 55 226 2.9E-65 T 15-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_23005 fd253317ea3edf84f766182d5316139a 596 Gene3D G3DSA:3.40.710.10 291 595 2.8E-191 T 15-10-2018 C2I28_23005 fd253317ea3edf84f766182d5316139a 596 Pfam PF00905 Penicillin binding protein transpeptidase domain 321 575 2.3E-35 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 Gene3D G3DSA:1.10.1740.10 2 107 1.3E-24 T 15-10-2018 C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 166 7.7E-28 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 Pfam PF04542 Sigma-70 region 2 21 88 3.0E-14 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 SUPERFAMILY SSF88659 105 167 7.66E-16 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 Gene3D G3DSA:1.10.10.10 111 169 2.2E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 SUPERFAMILY SSF88946 3 100 2.24E-24 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_26085 d0d0c1a1282c1579c1f19322d54b3c7a 175 Pfam PF04545 Sigma-70, region 4 118 165 7.6E-15 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 21 468 1.9E-203 T 15-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 Pfam PF00171 Aldehyde dehydrogenase family 14 469 6.4E-178 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 Gene3D G3DSA:3.40.605.10 13 465 2.3E-185 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 SUPERFAMILY SSF53720 3 472 3.4E-175 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 PIRSF PIRSF036492 23 471 5.4E-84 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_01935 0b17f75e7e1f69ede5e537e4042287a1 474 Gene3D G3DSA:3.40.309.10 252 442 2.3E-185 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_00755 4bc4904e360df5553f2eb1438e6c0cee 394 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 180 386 9.5E-70 T 15-10-2018 IPR010897 Sporulation stage II, protein P C2I28_00755 4bc4904e360df5553f2eb1438e6c0cee 394 SUPERFAMILY SSF53187 261 386 6.59E-8 T 15-10-2018 C2I28_00755 4bc4904e360df5553f2eb1438e6c0cee 394 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 103 382 3.9E-74 T 15-10-2018 IPR010897 Sporulation stage II, protein P C2I28_26500 671a6fdd0ade3e62b2ccefecabc27c0a 123 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 87 3.6E-12 T 15-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I28_26500 671a6fdd0ade3e62b2ccefecabc27c0a 123 SUPERFAMILY SSF56214 2 121 2.62E-16 T 15-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I28_26500 671a6fdd0ade3e62b2ccefecabc27c0a 123 Gene3D G3DSA:3.90.470.20 1 122 1.8E-15 T 15-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I28_26500 671a6fdd0ade3e62b2ccefecabc27c0a 123 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 76 1.0E-6 T 15-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I28_17430 80a145f6f2b9a1c56a1cbe698d8fc74a 473 Gene3D G3DSA:3.20.20.140 7 464 1.2E-197 T 15-10-2018 C2I28_17430 80a145f6f2b9a1c56a1cbe698d8fc74a 473 Gene3D G3DSA:1.10.2020.10 46 136 1.2E-197 T 15-10-2018 C2I28_17430 80a145f6f2b9a1c56a1cbe698d8fc74a 473 SUPERFAMILY SSF51556 2 464 1.45E-181 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_17430 80a145f6f2b9a1c56a1cbe698d8fc74a 473 Hamap MF_00675 Uronate isomerase [uxaC]. 2 466 50.16 T 15-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 C2I28_17430 80a145f6f2b9a1c56a1cbe698d8fc74a 473 Pfam PF02614 Glucuronate isomerase 1 464 1.5E-229 T 15-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 C2I28_14765 2c9edf4b08052f56ae5291c9884b325b 221 SUPERFAMILY SSF140423 23 210 1.44E-44 T 15-10-2018 IPR036785 YkyA-like superfamily C2I28_14765 2c9edf4b08052f56ae5291c9884b325b 221 Gene3D G3DSA:1.20.120.570 12 210 7.6E-49 T 15-10-2018 IPR036785 YkyA-like superfamily C2I28_14765 2c9edf4b08052f56ae5291c9884b325b 221 Pfam PF10368 Putative cell-wall binding lipoprotein 13 213 4.9E-58 T 15-10-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like C2I28_23805 ba89a78cf2bb45a0369314286ba580a7 105 Gene3D G3DSA:1.10.760.20 23 105 2.8E-34 T 15-10-2018 IPR038292 YmfJ/YflH superfamily C2I28_23805 ba89a78cf2bb45a0369314286ba580a7 105 Pfam PF11588 Protein of unknown function (DUF3243) 28 105 1.2E-31 T 15-10-2018 IPR021637 Protein of unknown function DUF3243 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 Gene3D G3DSA:2.70.98.60 1 310 3.5E-118 T 15-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 652 738 5.4E-24 T 15-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 30 286 3.0E-92 T 15-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 467 482 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 521 537 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 546 562 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 331 345 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 242 257 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 409 431 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 293 313 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PRINTS PR00743 Glycosyl hydrolase family 36 signature 359 374 1.1E-63 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 PIRSF PIRSF005536 1 741 0.0 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 Gene3D G3DSA:3.20.20.70 311 633 1.2E-135 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 ProSitePatterns PS00512 Alpha-galactosidase signature. 360 375 - T 15-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 Gene3D G3DSA:2.60.40.1180 634 741 7.4E-36 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 Pfam PF02065 Melibiase 290 636 2.8E-171 T 15-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 C2I28_10440 10e3a183a5ebae909daa28cc3bc223f4 741 SUPERFAMILY SSF51445 325 669 2.99E-114 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Gene3D G3DSA:3.50.30.10 475 586 3.0E-36 T 15-10-2018 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 343 6.3E-157 T 15-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 505 576 1.0E-21 T 15-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Gene3D G3DSA:2.40.33.10 71 167 1.5E-150 T 15-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 3.2E-36 T 15-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 SUPERFAMILY SSF50800 71 167 1.92E-26 T 15-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 SUPERFAMILY SSF52009 466 583 9.94E-31 T 15-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 473 4.9E-189 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 SUPERFAMILY SSF51621 1 343 3.49E-102 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 217 243 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 313 329 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 186 200 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 244 268 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 294 312 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 PRINTS PR01050 Pyruvate kinase family signature 269 293 8.9E-81 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Gene3D G3DSA:3.40.1380.20 340 474 4.6E-46 T 15-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 Gene3D G3DSA:3.20.20.60 4 332 1.5E-150 T 15-10-2018 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 SUPERFAMILY SSF52935 323 474 1.7E-43 T 15-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_05425 5b4cd4fe86177a02f5fb231a72f87656 586 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 15-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_08265 91139dc3ddd2f5c200a19b1409077abc 330 SUPERFAMILY SSF52540 11 196 8.7E-45 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08265 91139dc3ddd2f5c200a19b1409077abc 330 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 197 7.7E-62 T 15-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_08265 91139dc3ddd2f5c200a19b1409077abc 330 Gene3D G3DSA:3.40.50.300 8 169 2.9E-52 T 15-10-2018 C2I28_08265 91139dc3ddd2f5c200a19b1409077abc 330 Pfam PF13177 DNA polymerase III, delta subunit 12 170 5.3E-58 T 15-10-2018 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 SMART SM00436 125 215 3.1E-33 T 15-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 295 310 - T 15-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 Pfam PF01131 DNA topoisomerase 152 550 2.2E-130 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 Gene3D G3DSA:2.70.20.10 209 463 7.2E-135 T 15-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 Gene3D G3DSA:1.10.290.10 267 395 7.2E-135 T 15-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 SMART SM00437 258 516 3.9E-82 T 15-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 2.0E-28 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 479 493 2.0E-28 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 381 397 2.0E-28 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 301 310 2.0E-28 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 2.0E-28 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 SUPERFAMILY SSF56712 1 589 3.14E-175 T 15-10-2018 IPR023405 DNA topoisomerase, type IA, core domain C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 SMART SM00493 2 125 4.9E-22 T 15-10-2018 IPR006171 TOPRIM domain C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 672 5.0E-200 T 15-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 Pfam PF01751 Toprim domain 4 132 1.0E-14 T 15-10-2018 IPR006171 TOPRIM domain C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 Gene3D G3DSA:3.40.50.140 2 153 1.8E-52 T 15-10-2018 C2I28_19165 ea07ba2ee27262675f95d194147d3139 693 Gene3D G3DSA:1.10.460.10 159 560 7.2E-135 T 15-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 C2I28_20480 a4921285271e55e72a717be718f99cc5 185 Pfam PF09335 SNARE associated Golgi protein 27 139 7.7E-17 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 Gene3D G3DSA:3.30.565.10 304 448 1.5E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 Gene3D G3DSA:1.10.287.130 181 300 1.5E-25 T 15-10-2018 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 SUPERFAMILY SSF158472 178 228 1.96E-5 T 15-10-2018 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 403 3.7E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 3.7E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 3.7E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 3.7E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 SMART SM00387 341 448 4.0E-36 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 SUPERFAMILY SSF55874 289 448 2.1E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 448 3.3E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 SUPERFAMILY SSF47384 215 298 1.02E-16 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 SMART SM00388 232 299 1.6E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 SMART SM00304 177 231 2.3E-5 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_09665 54be7b030fd70490a9e003f11dab0824 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 298 2.5E-15 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_02265 272430371aa31e1a824529016c1b81c1 201 PIRSF PIRSF001390 1 194 8.1E-80 T 15-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B C2I28_02265 272430371aa31e1a824529016c1b81c1 201 SUPERFAMILY SSF52507 3 180 3.27E-29 T 15-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I28_02265 272430371aa31e1a824529016c1b81c1 201 Pfam PF02441 Flavoprotein 6 154 1.0E-15 T 15-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 C2I28_02265 272430371aa31e1a824529016c1b81c1 201 Gene3D G3DSA:3.40.50.1950 1 199 2.8E-57 T 15-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I28_02265 272430371aa31e1a824529016c1b81c1 201 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 2.2E-102 T 15-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 Pfam PF01274 Malate synthase 17 695 4.2E-171 T 15-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 Hamap MF_00641 Malate synthase G [glcB]. 1 725 375.876 T 15-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 Gene3D G3DSA:2.170.170.11 133 262 1.5E-270 T 15-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 SUPERFAMILY SSF51645 2 720 2.35E-300 T 15-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 Gene3D G3DSA:3.20.20.360 7 578 1.5E-270 T 15-10-2018 C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 720 0.0 T 15-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 C2I28_22475 3f1c860b9efaa7ff73c3d1d9c11b3961 725 Gene3D G3DSA:1.20.1220.12 581 725 2.1E-74 T 15-10-2018 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 SUPERFAMILY SSF48029 11 104 2.22E-20 T 15-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 Pfam PF01706 FliG C-terminal domain 223 329 6.8E-42 T 15-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 Pfam PF14842 FliG N-terminal domain 9 112 2.1E-35 T 15-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 Pfam PF14841 FliG middle domain 120 194 1.3E-32 T 15-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 Gene3D G3DSA:1.10.220.30 108 199 6.4E-35 T 15-10-2018 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 253 273 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 277 303 1.1E-76 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 PIRSF PIRSF003161 4 339 1.5E-122 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 SUPERFAMILY SSF48029 119 330 4.97E-69 T 15-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 Gene3D G3DSA:1.10.220.30 200 339 5.4E-48 T 15-10-2018 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 6 339 3.6E-149 T 15-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 C2I28_02525 6b1649bddcaace01065fb04ca91ccd2a 339 Gene3D G3DSA:1.10.220.30 3 90 6.4E-20 T 15-10-2018 C2I28_24510 c3504b351c6ba41e4eb33902b3b0bb4c 109 SUPERFAMILY SSF54862 6 67 4.54E-17 T 15-10-2018 C2I28_24510 c3504b351c6ba41e4eb33902b3b0bb4c 109 Pfam PF13187 4Fe-4S dicluster domain 9 56 2.9E-8 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_24510 c3504b351c6ba41e4eb33902b3b0bb4c 109 Gene3D G3DSA:3.30.70.20 2 71 7.8E-14 T 15-10-2018 C2I28_24510 c3504b351c6ba41e4eb33902b3b0bb4c 109 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_24510 c3504b351c6ba41e4eb33902b3b0bb4c 109 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 541 1.0E-130 T 15-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 SUPERFAMILY SSF51621 251 548 2.88E-114 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 Gene3D G3DSA:1.10.274.10 24 147 5.1E-82 T 15-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 SUPERFAMILY SSF52009 126 248 9.55E-38 T 15-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 SUPERFAMILY SSF47831 24 144 5.75E-39 T 15-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 567 2.4E-256 T 15-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 PIRSF PIRSF000732 1 572 2.5E-228 T 15-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 Gene3D G3DSA:3.50.30.10 7 235 5.1E-82 T 15-10-2018 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 5.6E-35 T 15-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 15-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 448 466 - T 15-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 1.5E-32 T 15-10-2018 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 1.5E-32 T 15-10-2018 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 480 1.5E-32 T 15-10-2018 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 501 513 1.5E-32 T 15-10-2018 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 Gene3D G3DSA:3.20.20.60 236 570 6.0E-128 T 15-10-2018 C2I28_14560 b93c0b629cd40b8e8ce89c5d8141b4c5 573 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 4.9E-22 T 15-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 SUPERFAMILY SSF118215 6 402 1.09E-124 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 2.1E-122 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 44 64 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 9.9E-44 T 15-10-2018 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 Gene3D G3DSA:1.10.3860.10 1 419 4.5E-132 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_16895 4d11e64af82da6087ef6f2a6565a098d 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_07750 0e3483c4f0bfa740d5f1268333599e15 258 SUPERFAMILY SSF53474 5 254 2.68E-45 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_07750 0e3483c4f0bfa740d5f1268333599e15 258 Pfam PF00756 Putative esterase 25 252 1.8E-25 T 15-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 C2I28_07750 0e3483c4f0bfa740d5f1268333599e15 258 Gene3D G3DSA:3.40.50.1820 1 257 1.4E-74 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 Gene3D G3DSA:3.40.190.10 39 322 1.9E-125 T 15-10-2018 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 6.2E-60 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 Gene3D G3DSA:3.40.190.10 139 330 1.9E-125 T 15-10-2018 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 PIRSF PIRSF019574 1 356 5.9E-135 T 15-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 Pfam PF13416 Bacterial extracellular solute-binding protein 50 321 1.5E-46 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_09070 325562f9b41c9fa2b8395414c06b1f02 357 SUPERFAMILY SSF53850 34 353 3.22E-101 T 15-10-2018 C2I28_24610 12108a9c609a57fd315f5d30168e4d33 98 SMART SM00450 4 96 8.9E-19 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24610 12108a9c609a57fd315f5d30168e4d33 98 Gene3D G3DSA:3.40.250.10 1 97 5.4E-30 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_24610 12108a9c609a57fd315f5d30168e4d33 98 Pfam PF00581 Rhodanese-like domain 6 95 1.2E-15 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24610 12108a9c609a57fd315f5d30168e4d33 98 SUPERFAMILY SSF52821 2 95 2.23E-31 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_00110 326ae1f70863347f2f7f1b727028b93b 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 1.1E-35 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_00110 326ae1f70863347f2f7f1b727028b93b 312 Gene3D G3DSA:3.10.180.10 67 210 6.4E-124 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_00110 326ae1f70863347f2f7f1b727028b93b 312 SUPERFAMILY SSF54593 5 283 1.19E-45 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_00110 326ae1f70863347f2f7f1b727028b93b 312 Gene3D G3DSA:3.10.180.10 7 303 6.4E-124 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 301 317 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 245 263 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 411 427 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 150 179 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 88 112 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 270 286 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PRINTS PR00072 Malic enzyme signature 186 208 3.0E-71 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 SUPERFAMILY SSF51735 274 562 4.82E-92 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 Gene3D G3DSA:3.40.50.720 272 567 8.0E-109 T 15-10-2018 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 Pfam PF03949 Malic enzyme, NAD binding domain 274 532 2.1E-105 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 Pfam PF00390 Malic enzyme, N-terminal domain 82 263 1.7E-72 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 SMART SM01274 82 264 8.4E-93 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 SMART SM00919 274 533 1.3E-123 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 ProSitePatterns PS00331 Malic enzymes signature. 270 286 - T 15-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 PIRSF PIRSF000106 2 563 8.1E-223 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 Gene3D G3DSA:3.40.50.10380 16 271 7.1E-103 T 15-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I28_18100 d5fe14a212aef8b0be06e4a251feaca2 569 SUPERFAMILY SSF53223 5 273 5.18E-102 T 15-10-2018 C2I28_20435 a2765167f42a76950139615886551018 331 SMART SM00797 24 317 3.7E-139 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_20435 a2765167f42a76950139615886551018 331 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 324 6.9E-97 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_20435 a2765167f42a76950139615886551018 331 SUPERFAMILY SSF50891 193 307 4.17E-11 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_20435 a2765167f42a76950139615886551018 331 Gene3D G3DSA:2.40.100.10 190 328 1.4E-50 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_20435 a2765167f42a76950139615886551018 331 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 300 1.2E-95 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Pfam PF13604 AAA domain 344 551 9.2E-51 T 15-10-2018 C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Gene3D G3DSA:2.30.30.940 601 680 2.5E-142 T 15-10-2018 C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Gene3D G3DSA:3.40.50.300 335 749 2.5E-142 T 15-10-2018 C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 17 750 9.5E-261 T 15-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Pfam PF13538 UvrD-like helicase C-terminal domain 679 727 3.3E-17 T 15-10-2018 IPR027785 UvrD-like helicase C-terminal domain C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Gene3D G3DSA:3.40.50.300 515 743 2.5E-142 T 15-10-2018 C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 SMART SM00382 357 511 0.0077 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 SUPERFAMILY SSF52540 340 733 1.49E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Pfam PF14490 Helix-hairpin-helix containing domain 157 248 8.5E-32 T 15-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 13 764 29.453 T 15-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 C2I28_04625 b5e81e746b9b99b191b9b7206f482f8b 785 Gene3D G3DSA:1.10.10.2220 199 296 8.4E-18 T 15-10-2018 C2I28_16810 3ceffd91d5a06fb173134c8da78e3b64 150 SUPERFAMILY SSF54593 2 145 4.63E-32 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_16810 3ceffd91d5a06fb173134c8da78e3b64 150 Gene3D G3DSA:3.10.180.10 1 150 9.4E-61 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_16810 3ceffd91d5a06fb173134c8da78e3b64 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 132 8.3E-9 T 15-10-2018 C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 442 452 - T 15-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 Gene3D G3DSA:2.40.50.140 2 86 1.3E-23 T 15-10-2018 C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 Gene3D G3DSA:3.40.1350.30 137 292 1.0E-112 T 15-10-2018 C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 391 422 - T 15-10-2018 IPR030390 RNA methyltransferase TrmA, active site C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 Pfam PF01938 TRAM domain 10 65 2.6E-10 T 15-10-2018 IPR002792 TRAM domain C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 Gene3D G3DSA:3.40.50.150 88 454 1.0E-112 T 15-10-2018 C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 SUPERFAMILY SSF50249 3 65 1.37E-15 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 SUPERFAMILY SSF53335 75 456 4.99E-78 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 452 1.5E-179 T 15-10-2018 C2I28_10020 8e509d2d04edcf29eb5f991514f2e468 461 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 130 458 4.4E-17 T 15-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 SUPERFAMILY SSF46589 14 100 2.88E-22 T 15-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 1.6E-115 T 15-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 22 88 1.9E-26 T 15-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 2.4E-110 T 15-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 Gene3D G3DSA:3.30.930.10 8 344 7.3E-127 T 15-10-2018 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 SUPERFAMILY SSF55681 93 342 1.44E-82 T 15-10-2018 C2I28_05270 f7da1264bb6011754ba2c3cfd8466cab 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 49.327 T 15-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 C2I28_12750 88023923faf2a1803049575be7766d9c 866 Gene3D G3DSA:1.20.1270.50 279 378 1.9E-29 T 15-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 C2I28_12750 88023923faf2a1803049575be7766d9c 866 SUPERFAMILY SSF88713 1 256 3.26E-52 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_12750 88023923faf2a1803049575be7766d9c 866 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 3 265 1.1E-41 T 15-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 C2I28_12750 88023923faf2a1803049575be7766d9c 866 Gene3D G3DSA:3.20.110.10 1 272 1.8E-103 T 15-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily C2I28_12750 88023923faf2a1803049575be7766d9c 866 Gene3D G3DSA:2.70.98.30 474 758 4.3E-77 T 15-10-2018 C2I28_12750 88023923faf2a1803049575be7766d9c 866 SUPERFAMILY SSF74650 371 862 5.96E-74 T 15-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I28_12750 88023923faf2a1803049575be7766d9c 866 SUPERFAMILY SSF88688 276 372 6.28E-9 T 15-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily C2I28_12750 88023923faf2a1803049575be7766d9c 866 Pfam PF09261 Alpha mannosidase middle domain 276 352 1.2E-9 T 15-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 C2I28_12750 88023923faf2a1803049575be7766d9c 866 SMART SM00872 275 353 3.3E-19 T 15-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 C2I28_12750 88023923faf2a1803049575be7766d9c 866 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 384 861 3.7E-36 T 15-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 C2I28_12750 88023923faf2a1803049575be7766d9c 866 Gene3D G3DSA:2.60.40.2220 787 851 4.3E-5 T 15-10-2018 C2I28_11805 6f5d8ea4582a0498bfcd5b249820c0cb 196 Gene3D G3DSA:2.40.320.10 1 191 2.0E-54 T 15-10-2018 C2I28_11805 6f5d8ea4582a0498bfcd5b249820c0cb 196 Pfam PF01928 CYTH domain 4 186 2.0E-34 T 15-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 C2I28_11805 6f5d8ea4582a0498bfcd5b249820c0cb 196 PIRSF PIRSF012526 1 193 1.1E-68 T 15-10-2018 IPR009195 Uncharacterised protein family YjbK C2I28_11805 6f5d8ea4582a0498bfcd5b249820c0cb 196 SUPERFAMILY SSF55154 5 188 4.25E-32 T 15-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 C2I28_11805 6f5d8ea4582a0498bfcd5b249820c0cb 196 SMART SM01118 4 192 3.5E-21 T 15-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 330 3.8E-25 T 15-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 Gene3D G3DSA:3.40.50.1220 189 361 1.1E-35 T 15-10-2018 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 177 1.1E-49 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 Gene3D G3DSA:3.40.50.970 365 558 3.2E-62 T 15-10-2018 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 SUPERFAMILY SSF52518 10 184 1.22E-47 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_12120 f61af98e0e6326551363e6982a6253be 559 SUPERFAMILY SSF52467 191 358 1.31E-34 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_12120 f61af98e0e6326551363e6982a6253be 559 SUPERFAMILY SSF52518 367 548 6.11E-61 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_12120 f61af98e0e6326551363e6982a6253be 559 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 15-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 13 550 6.9E-253 T 15-10-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 Gene3D G3DSA:3.40.50.970 2 188 1.0E-63 T 15-10-2018 C2I28_12120 f61af98e0e6326551363e6982a6253be 559 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 539 5.3E-44 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 Gene3D G3DSA:3.30.1490.20 131 202 2.9E-161 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 449 8.7E-241 T 15-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.2E-46 T 15-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 Gene3D G3DSA:3.30.470.20 87 443 2.9E-161 T 15-10-2018 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 Gene3D G3DSA:3.40.50.20 2 85 2.8E-37 T 15-10-2018 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.9E-83 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 SUPERFAMILY SSF52440 1 113 1.15E-49 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 SMART SM00878 337 443 3.1E-71 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 3.6E-45 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 SUPERFAMILY SSF56059 83 349 1.45E-72 T 15-10-2018 C2I28_03865 4623a45fbc4be589d2e365128aa6b618 450 SUPERFAMILY SSF51246 332 443 1.31E-47 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 SMART SM00448 7 117 4.5E-43 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 SUPERFAMILY SSF46894 132 225 2.18E-24 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 SMART SM00862 150 224 3.9E-22 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 Pfam PF00072 Response regulator receiver domain 9 118 8.8E-28 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 224 7.5E-24 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 Gene3D G3DSA:3.40.50.2300 2 127 1.6E-36 T 15-10-2018 C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 SUPERFAMILY SSF52172 4 124 3.84E-40 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_07805 d0640e8fbcf993926c377b40c5b3ee45 227 Gene3D G3DSA:1.10.10.10 129 227 5.1E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00570 70913298d43329ed26bbe324c189ab4c 220 Pfam PF00174 Oxidoreductase molybdopterin binding domain 39 185 1.9E-41 T 15-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 C2I28_00570 70913298d43329ed26bbe324c189ab4c 220 SUPERFAMILY SSF56524 22 204 3.66E-63 T 15-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 C2I28_00570 70913298d43329ed26bbe324c189ab4c 220 Gene3D G3DSA:3.90.420.10 29 209 3.7E-47 T 15-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 C2I28_00570 70913298d43329ed26bbe324c189ab4c 220 PRINTS PR00407 Eukaryotic molybdopterin domain signature 148 161 1.7E-6 T 15-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 C2I28_00570 70913298d43329ed26bbe324c189ab4c 220 PRINTS PR00407 Eukaryotic molybdopterin domain signature 131 147 1.7E-6 T 15-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 C2I28_00570 70913298d43329ed26bbe324c189ab4c 220 PRINTS PR00407 Eukaryotic molybdopterin domain signature 164 177 1.7E-6 T 15-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 458 2.0E-171 T 15-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 4.9E-33 T 15-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 Gene3D G3DSA:3.50.50.60 146 265 9.5E-112 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PIRSF PIRSF000350 1 452 3.9E-84 T 15-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 SUPERFAMILY SSF51905 4 367 6.68E-59 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 321 2.1E-68 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 SUPERFAMILY SSF55424 336 458 4.12E-37 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 6.3E-64 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.8E-38 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.8E-38 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 2.8E-38 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.8E-38 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 2.8E-38 T 15-10-2018 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 Gene3D G3DSA:3.50.50.60 5 325 9.5E-112 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 15-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 C2I28_17370 d95a54fd7353a88b57527805c16b107c 459 Gene3D G3DSA:3.30.390.30 339 459 8.4E-39 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_13530 7ee23329bd5c16b5c18ce9fecfcbf928 171 Pfam PF07883 Cupin domain 48 110 3.1E-13 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_13530 7ee23329bd5c16b5c18ce9fecfcbf928 171 SUPERFAMILY SSF51182 19 143 6.4E-22 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_13530 7ee23329bd5c16b5c18ce9fecfcbf928 171 Gene3D G3DSA:2.60.120.10 2 166 6.1E-38 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_00330 04381aed353f4c4a6876d49438ed72d0 222 Pfam PF01569 PAP2 superfamily 89 206 1.0E-23 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_00330 04381aed353f4c4a6876d49438ed72d0 222 Gene3D G3DSA:1.20.144.10 122 222 3.2E-30 T 15-10-2018 C2I28_00330 04381aed353f4c4a6876d49438ed72d0 222 Gene3D G3DSA:1.20.144.10 3 121 7.5E-10 T 15-10-2018 C2I28_00330 04381aed353f4c4a6876d49438ed72d0 222 SUPERFAMILY SSF48317 13 211 6.67E-43 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_00330 04381aed353f4c4a6876d49438ed72d0 222 SMART SM00014 87 201 5.9E-30 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_06520 fbeabb70fb3d39183c6a79027a06248e 144 SUPERFAMILY SSF82649 2 142 9.72E-53 T 15-10-2018 C2I28_06520 fbeabb70fb3d39183c6a79027a06248e 144 Pfam PF01592 NifU-like N terminal domain 10 128 3.3E-36 T 15-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 C2I28_06520 fbeabb70fb3d39183c6a79027a06248e 144 Gene3D G3DSA:3.90.1010.10 2 144 1.3E-60 T 15-10-2018 C2I28_06520 fbeabb70fb3d39183c6a79027a06248e 144 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 140 2.6E-59 T 15-10-2018 C2I28_13945 c81387bf90f81c8fbe92c9db4cdac60b 241 Hamap MF_01240 UPF0309 protein . 1 241 38.399 T 15-10-2018 IPR022951 Uncharacterised protein family UPF0309 C2I28_13945 c81387bf90f81c8fbe92c9db4cdac60b 241 Pfam PF13580 SIS domain 5 139 3.9E-42 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_13945 c81387bf90f81c8fbe92c9db4cdac60b 241 SUPERFAMILY SSF53697 6 171 1.72E-23 T 15-10-2018 C2I28_13945 c81387bf90f81c8fbe92c9db4cdac60b 241 Gene3D G3DSA:3.40.50.10490 2 236 3.8E-81 T 15-10-2018 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 SUPERFAMILY SSF63882 8 184 1.57E-48 T 15-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Gene3D G3DSA:3.90.105.10 27 183 1.6E-114 T 15-10-2018 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Gene3D G3DSA:2.170.190.11 50 150 1.6E-114 T 15-10-2018 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Gene3D G3DSA:3.40.980.10 184 337 1.6E-114 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 1.7E-36 T 15-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 SMART SM00852 189 327 1.5E-38 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 187 323 5.3E-31 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 SUPERFAMILY SSF53218 186 330 3.53E-38 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 SUPERFAMILY SSF63867 336 412 8.11E-14 T 15-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Pfam PF03454 MoeA C-terminal region (domain IV) 340 410 2.4E-18 T 15-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Pfam PF00994 Probable molybdopterin binding domain 189 326 1.7E-23 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_00555 1e5ecdf892cf3f94c7035825547dc7fe 421 Gene3D G3DSA:2.40.340.10 338 405 1.6E-114 T 15-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_07200 50be1efe69bbefc35f5df8b3fa40e4f1 350 ProSitePatterns PS01348 MraY family signature 2. 145 156 - T 15-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_07200 50be1efe69bbefc35f5df8b3fa40e4f1 350 Pfam PF00953 Glycosyl transferase family 4 72 225 3.8E-40 T 15-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 C2I28_24100 7b42d4e05bb6c9925ed4799fed7dc867 227 Pfam PF03741 Integral membrane protein TerC family 13 183 2.0E-45 T 15-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I28_24100 7b42d4e05bb6c9925ed4799fed7dc867 227 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 184 5.2E-65 T 15-10-2018 IPR022301 Integral membrane protein YjbE C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 SMART SM00347 27 127 6.5E-18 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 3.1E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.1E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.1E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.1E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 Pfam PF01047 MarR family 35 91 2.2E-14 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 SUPERFAMILY SSF46785 24 141 3.96E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18350 891d14af8adf8a70a4f375367d8c3fb8 143 Gene3D G3DSA:1.10.10.10 1 141 6.7E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_15175 00d55cf8d75b259a6d68fff2e6620300 163 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 9 64 2.0E-12 T 15-10-2018 IPR020108 Spore coat protein CotD C2I28_15175 00d55cf8d75b259a6d68fff2e6620300 163 Pfam PF11122 Inner spore coat protein D 10 111 6.6E-25 T 15-10-2018 IPR020108 Spore coat protein CotD C2I28_10370 fe0f4f039afcf8c772554457721b0739 508 PIRSF PIRSF005690 20 503 1.3E-152 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_10370 fe0f4f039afcf8c772554457721b0739 508 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 38 487 3.9E-151 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 Gene3D G3DSA:3.40.50.2300 163 298 4.0E-57 T 15-10-2018 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 Pfam PF13377 Periplasmic binding protein-like domain 172 337 3.6E-38 T 15-10-2018 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 SUPERFAMILY SSF53822 67 331 2.16E-53 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 SUPERFAMILY SSF47413 1 49 9.38E-13 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 15-10-2018 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 Gene3D G3DSA:3.40.50.2300 79 329 4.0E-57 T 15-10-2018 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 Gene3D G3DSA:1.10.260.40 1 60 7.7E-18 T 15-10-2018 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.6E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.6E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 1.5E-17 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_21955 944443d016f06518d1f06744e6f6bffe 344 SMART SM00354 1 76 1.1E-14 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19390 6b62faa1e08a4cf99764e8301bbf01db 306 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 26 271 7.7E-36 T 15-10-2018 C2I28_19390 6b62faa1e08a4cf99764e8301bbf01db 306 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 17 299 18.793 T 15-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 C2I28_19390 6b62faa1e08a4cf99764e8301bbf01db 306 PIRSF PIRSF005355 10 304 1.5E-84 T 15-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 C2I28_19390 6b62faa1e08a4cf99764e8301bbf01db 306 Pfam PF01040 UbiA prenyltransferase family 34 262 9.8E-36 T 15-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 C2I28_06405 3f54472e93429298685fa648344a7ca0 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 4 78 1.0E-29 T 15-10-2018 C2I28_06405 3f54472e93429298685fa648344a7ca0 79 Hamap MF_01542 UPF0349 protein . 2 78 29.529 T 15-10-2018 IPR022916 Protein of unknown function UPF0349 C2I28_06405 3f54472e93429298685fa648344a7ca0 79 Pfam PF07293 Protein of unknown function (DUF1450) 2 76 7.5E-37 T 15-10-2018 IPR009910 Protein of unknown function DUF1450 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 6.0E-142 T 15-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 15-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 Pfam PF04055 Radical SAM superfamily 149 319 1.5E-27 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 Gene3D G3DSA:3.80.30.20 140 375 1.7E-86 T 15-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 SMART SM00729 143 361 5.6E-57 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 2.0E-150 T 15-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 Gene3D G3DSA:3.40.50.12160 3 133 6.2E-25 T 15-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 1.4E-26 T 15-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 C2I28_04360 e1b09018b9e8702e4697277d0403974d 452 SUPERFAMILY SSF102114 124 365 2.09E-57 T 15-10-2018 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 Gene3D G3DSA:3.40.50.9100 1 145 4.4E-67 T 15-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 Pfam PF01220 Dehydroquinase class II 3 139 1.1E-63 T 15-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 PIRSF PIRSF001399 1 145 1.9E-64 T 15-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 141 5.7E-67 T 15-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 SUPERFAMILY SSF52304 3 143 4.32E-61 T 15-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 145 68.331 T 15-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 141 6.0E-52 T 15-10-2018 C2I28_03930 131b7828557e1b1e00c2f092cd0c6868 145 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 15-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 C2I28_05850 edaa926cc9ebb1be4e2a903d7f9a4622 381 Gene3D G3DSA:3.40.50.2000 1 194 3.8E-28 T 15-10-2018 C2I28_05850 edaa926cc9ebb1be4e2a903d7f9a4622 381 SUPERFAMILY SSF53756 2 372 6.67E-82 T 15-10-2018 C2I28_05850 edaa926cc9ebb1be4e2a903d7f9a4622 381 Pfam PF13439 Glycosyltransferase Family 4 14 177 4.8E-26 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_05850 edaa926cc9ebb1be4e2a903d7f9a4622 381 Pfam PF00534 Glycosyl transferases group 1 188 348 1.6E-37 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_05850 edaa926cc9ebb1be4e2a903d7f9a4622 381 Gene3D G3DSA:3.40.50.2000 195 359 1.6E-40 T 15-10-2018 C2I28_08605 ab967f9140ea4982be1d344783abadbf 49 Gene3D G3DSA:2.20.28.120 1 49 4.7E-20 T 15-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08605 ab967f9140ea4982be1d344783abadbf 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.79 T 15-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08605 ab967f9140ea4982be1d344783abadbf 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 4.6E-20 T 15-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08605 ab967f9140ea4982be1d344783abadbf 49 SUPERFAMILY SSF57829 1 49 3.54E-17 T 15-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I28_08605 ab967f9140ea4982be1d344783abadbf 49 Pfam PF00471 Ribosomal protein L33 3 49 1.8E-20 T 15-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_27480 1773914f8cdc233ef844460f6ddcc960 328 Gene3D G3DSA:3.40.50.720 4 307 9.7E-118 T 15-10-2018 C2I28_27480 1773914f8cdc233ef844460f6ddcc960 328 Pfam PF02719 Polysaccharide biosynthesis protein 7 279 4.4E-100 T 15-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain C2I28_27480 1773914f8cdc233ef844460f6ddcc960 328 Gene3D G3DSA:3.90.25.30 165 319 9.7E-118 T 15-10-2018 C2I28_27480 1773914f8cdc233ef844460f6ddcc960 328 SUPERFAMILY SSF51735 4 260 6.29E-59 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17745 22b8a0e2b853d5a4052547fe4bae04ab 217 Gene3D G3DSA:1.10.472.50 1 97 6.9E-33 T 15-10-2018 C2I28_17745 22b8a0e2b853d5a4052547fe4bae04ab 217 SMART SM00471 19 133 1.2E-8 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_17745 22b8a0e2b853d5a4052547fe4bae04ab 217 Gene3D G3DSA:1.20.58.1910 98 216 2.5E-47 T 15-10-2018 C2I28_17745 22b8a0e2b853d5a4052547fe4bae04ab 217 SUPERFAMILY SSF109604 2 210 1.28E-68 T 15-10-2018 C2I28_17745 22b8a0e2b853d5a4052547fe4bae04ab 217 Pfam PF01966 HD domain 25 123 9.8E-9 T 15-10-2018 IPR006674 HD domain C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 15-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 SUPERFAMILY SSF54506 2 281 1.96E-50 T 15-10-2018 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 8.3E-93 T 15-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 Gene3D G3DSA:3.10.310.10 6 280 2.6E-105 T 15-10-2018 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 Pfam PF01678 Diaminopimelate epimerase 6 129 1.7E-31 T 15-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 Pfam PF01678 Diaminopimelate epimerase 161 276 8.9E-32 T 15-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 37.261 T 15-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 C2I28_06400 94c145601b4426f5c1f703c5d602c11e 284 Gene3D G3DSA:3.10.310.10 126 274 2.6E-105 T 15-10-2018 C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 SMART SM01091 355 432 7.9E-19 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 SUPERFAMILY SSF54631 204 342 2.15E-24 T 15-10-2018 C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 Gene3D G3DSA:3.10.580.10 195 348 1.1E-46 T 15-10-2018 C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 Pfam PF03471 Transporter associated domain 356 431 5.4E-14 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 Pfam PF01595 Domain of unknown function DUF21 8 201 1.8E-47 T 15-10-2018 IPR002550 CNNM, transmembrane domain C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 SUPERFAMILY SSF56176 353 438 9.54E-16 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 Gene3D G3DSA:3.30.465.10 349 440 7.6E-15 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 Pfam PF00571 CBS domain 290 339 9.3E-4 T 15-10-2018 IPR000644 CBS domain C2I28_23090 ad6e6d4872212a0afb6b70d6f3930f08 441 Pfam PF00571 CBS domain 218 270 0.0062 T 15-10-2018 IPR000644 CBS domain C2I28_20760 2a6af23571422dfb3498c5c0a2c00431 360 Pfam PF00589 Phage integrase family 172 345 6.9E-27 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_20760 2a6af23571422dfb3498c5c0a2c00431 360 SUPERFAMILY SSF56349 40 347 1.06E-40 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_20760 2a6af23571422dfb3498c5c0a2c00431 360 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 43 115 1.6E-7 T 15-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I28_20760 2a6af23571422dfb3498c5c0a2c00431 360 Gene3D G3DSA:1.10.443.10 163 350 4.1E-38 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_20760 2a6af23571422dfb3498c5c0a2c00431 360 Gene3D G3DSA:1.10.150.130 32 146 2.0E-9 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 Gene3D G3DSA:3.40.50.11060 22 141 1.6E-41 T 15-10-2018 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 203 223 1.6E-8 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 270 288 1.6E-8 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 Hamap MF_00900 GTPase HflX [hflX]. 30 387 47.098 T 15-10-2018 IPR016496 GTPase HflX GO:0005525 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 Pfam PF13167 GTP-binding GTPase N-terminal 27 115 8.3E-33 T 15-10-2018 IPR025121 GTPase HflX, N-terminal C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 SUPERFAMILY SSF52540 201 370 5.5E-36 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 Gene3D G3DSA:3.40.50.300 201 383 1.1E-32 T 15-10-2018 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 Pfam PF01926 50S ribosome-binding GTPase 202 321 9.5E-20 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 PIRSF PIRSF006809 3 419 2.6E-148 T 15-10-2018 IPR016496 GTPase HflX GO:0005525 C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 Pfam PF16360 GTP-binding GTPase Middle Region 117 195 8.7E-32 T 15-10-2018 IPR032305 GTP-binding protein, middle domain C2I28_02075 018eb36d6585e7659468fb75e1ee5a20 420 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 357 3.7E-144 T 15-10-2018 IPR016496 GTPase HflX GO:0005525 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 Gene3D G3DSA:3.40.1190.20 212 498 1.6E-81 T 15-10-2018 IPR029056 Ribokinase-like C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 204 22.171 T 15-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 SUPERFAMILY SSF53613 217 496 4.68E-67 T 15-10-2018 IPR029056 Ribokinase-like C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 Pfam PF01256 Carbohydrate kinase 244 490 1.4E-59 T 15-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 314 324 - T 15-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 433 443 - T 15-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 SUPERFAMILY SSF64153 1 240 4.97E-54 T 15-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 Gene3D G3DSA:3.40.50.10260 1 211 4.0E-57 T 15-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 219 499 21.388 T 15-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 217 495 4.1E-62 T 15-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 4 205 2.4E-46 T 15-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 Pfam PF03853 YjeF-related protein N-terminus 25 181 2.1E-42 T 15-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 C2I28_18725 87747c76366557e4f99ec8a9e01c76f2 500 PIRSF PIRSF017184 1 500 9.3E-140 T 15-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 322 1.0E-131 T 15-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 SUPERFAMILY SSF82649 243 329 3.4E-28 T 15-10-2018 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 Gene3D G3DSA:3.30.390.50 243 329 6.0E-34 T 15-10-2018 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 Gene3D G3DSA:3.30.930.10 3 242 3.2E-81 T 15-10-2018 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 328 1.9E-32 T 15-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 151 1.1E-12 T 15-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I28_11205 d80f6d75b981750cb6531cebd43e53cf 329 SUPERFAMILY SSF55681 2 241 7.81E-81 T 15-10-2018 C2I28_18470 89ac18c332dbf76067fadb395c8bded4 279 PIRSF PIRSF006483 1 278 2.2E-86 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_18470 89ac18c332dbf76067fadb395c8bded4 279 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 1.8E-22 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_18470 89ac18c332dbf76067fadb395c8bded4 279 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 7.4E-65 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_18470 89ac18c332dbf76067fadb395c8bded4 279 Gene3D G3DSA:3.30.70.120 189 263 8.0E-24 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Pfam PF02954 Bacterial regulatory protein, Fis family 551 590 4.0E-10 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Gene3D G3DSA:3.40.50.300 309 461 1.5E-29 T 15-10-2018 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 SUPERFAMILY SSF159800 1 182 6.67E-53 T 15-10-2018 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Pfam PF14532 Sigma-54 interaction domain 328 460 5.2E-19 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Pfam PF06506 Propionate catabolism activator 23 182 3.0E-55 T 15-10-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 SUPERFAMILY SSF52540 310 533 1.96E-28 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Gene3D G3DSA:1.10.10.60 532 590 1.1E-13 T 15-10-2018 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Gene3D G3DSA:3.40.50.10660 75 164 9.6E-62 T 15-10-2018 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Gene3D G3DSA:1.10.8.60 462 531 3.1E-16 T 15-10-2018 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 SUPERFAMILY SSF46689 540 590 3.99E-9 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_17130 c786d30b4bc659c0c49d1bf69617a4c0 590 Gene3D G3DSA:3.40.50.2300 4 180 9.6E-62 T 15-10-2018 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 Gene3D G3DSA:1.20.5.710 1 50 6.2E-22 T 15-10-2018 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 49 1.7E-21 T 15-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 55 120 3.0E-17 T 15-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 120 2.9E-50 T 15-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 54 120 1.6E-30 T 15-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 120 25.709 T 15-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 SUPERFAMILY SSF54736 50 120 2.27E-25 T 15-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 SUPERFAMILY SSF48300 1 55 1.83E-16 T 15-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08635 2e3cf4ed71a16182aca5995053d08923 120 Gene3D G3DSA:3.30.1390.10 51 120 1.3E-31 T 15-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like C2I28_22820 018d4cd5bf0696b96c6c9a12b8a0a12a 427 SMART SM00382 27 218 3.1E-15 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_22820 018d4cd5bf0696b96c6c9a12b8a0a12a 427 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_22820 018d4cd5bf0696b96c6c9a12b8a0a12a 427 Gene3D G3DSA:3.40.50.300 1 258 1.7E-64 T 15-10-2018 C2I28_22820 018d4cd5bf0696b96c6c9a12b8a0a12a 427 SUPERFAMILY SSF52540 2 223 1.16E-57 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_22820 018d4cd5bf0696b96c6c9a12b8a0a12a 427 Pfam PF00005 ABC transporter 19 169 7.4E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_26215 4fd30a02ac660da1289ce42f80c4ffa1 263 Gene3D G3DSA:1.10.1660.10 33 165 4.2E-17 T 15-10-2018 C2I28_26215 4fd30a02ac660da1289ce42f80c4ffa1 263 Pfam PF13411 MerR HTH family regulatory protein 42 109 3.6E-14 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_26215 4fd30a02ac660da1289ce42f80c4ffa1 263 SUPERFAMILY SSF46955 41 145 1.28E-14 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_26215 4fd30a02ac660da1289ce42f80c4ffa1 263 SMART SM00422 41 110 1.7E-4 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27065 4fd30a02ac660da1289ce42f80c4ffa1 263 Gene3D G3DSA:1.10.1660.10 33 165 4.2E-17 T 15-10-2018 C2I28_27065 4fd30a02ac660da1289ce42f80c4ffa1 263 Pfam PF13411 MerR HTH family regulatory protein 42 109 3.6E-14 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27065 4fd30a02ac660da1289ce42f80c4ffa1 263 SUPERFAMILY SSF46955 41 145 1.28E-14 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_27065 4fd30a02ac660da1289ce42f80c4ffa1 263 SMART SM00422 41 110 1.7E-4 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27165 4fd30a02ac660da1289ce42f80c4ffa1 263 Gene3D G3DSA:1.10.1660.10 33 165 4.2E-17 T 15-10-2018 C2I28_27165 4fd30a02ac660da1289ce42f80c4ffa1 263 Pfam PF13411 MerR HTH family regulatory protein 42 109 3.6E-14 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27165 4fd30a02ac660da1289ce42f80c4ffa1 263 SUPERFAMILY SSF46955 41 145 1.28E-14 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_27165 4fd30a02ac660da1289ce42f80c4ffa1 263 SMART SM00422 41 110 1.7E-4 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_03895 959c4fce774a87ac553bf359d8b4436d 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 1 55 3.0E-12 T 15-10-2018 IPR025664 Stage III sporulation protein AC/AD family C2I28_03895 959c4fce774a87ac553bf359d8b4436d 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 69 124 4.9E-19 T 15-10-2018 IPR025664 Stage III sporulation protein AC/AD family C2I28_03895 959c4fce774a87ac553bf359d8b4436d 127 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 25 125 1.5E-36 T 15-10-2018 IPR014211 Stage III sporulation protein AD C2I28_24225 5f461f9eb977d29a1c0a499e1458ae5a 218 Gene3D G3DSA:1.10.10.60 1 53 1.6E-18 T 15-10-2018 C2I28_24225 5f461f9eb977d29a1c0a499e1458ae5a 218 SUPERFAMILY SSF46689 2 65 2.31E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_24225 5f461f9eb977d29a1c0a499e1458ae5a 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 9.2E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_24225 5f461f9eb977d29a1c0a499e1458ae5a 218 Gene3D G3DSA:1.10.357.10 55 217 9.9E-8 T 15-10-2018 C2I28_06575 086ded43546a3e7230772384e49f2371 127 Gene3D G3DSA:2.40.50.100 1 124 6.1E-54 T 15-10-2018 C2I28_06575 086ded43546a3e7230772384e49f2371 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 41.078 T 15-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 C2I28_06575 086ded43546a3e7230772384e49f2371 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 126 2.6E-59 T 15-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 C2I28_06575 086ded43546a3e7230772384e49f2371 127 SUPERFAMILY SSF51230 3 125 8.57E-48 T 15-10-2018 IPR011053 Single hybrid motif C2I28_06575 086ded43546a3e7230772384e49f2371 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 15-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I28_06575 086ded43546a3e7230772384e49f2371 127 Pfam PF01597 Glycine cleavage H-protein 7 126 1.4E-51 T 15-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate C2I28_21160 663b365551a551dd160109b57584bcc9 189 SUPERFAMILY SSF55469 1 188 9.03E-35 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_21160 663b365551a551dd160109b57584bcc9 189 Pfam PF00881 Nitroreductase family 7 165 2.6E-23 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_21160 663b365551a551dd160109b57584bcc9 189 Gene3D G3DSA:3.40.109.10 1 185 5.5E-40 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 Gene3D G3DSA:1.10.8.100 220 290 2.3E-22 T 15-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 SUPERFAMILY SSF53335 16 289 2.97E-74 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 288 56.515 T 15-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 SMART SM00650 36 212 9.9E-86 T 15-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 20 286 4.6E-86 T 15-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 279 1.5E-78 T 15-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 15-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 C2I28_08315 30d4aec35e9282f20bbb80f5bedc0468 292 Gene3D G3DSA:3.40.50.150 2 216 1.5E-73 T 15-10-2018 C2I28_22205 dae7f985681c7d52c61d08a36a60decd 368 Gene3D G3DSA:3.60.21.10 128 305 4.5E-6 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_22205 dae7f985681c7d52c61d08a36a60decd 368 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 60 285 5.8E-55 T 15-10-2018 IPR019079 Capsule synthesis protein, CapA C2I28_22205 dae7f985681c7d52c61d08a36a60decd 368 SMART SM00854 59 286 1.5E-80 T 15-10-2018 IPR019079 Capsule synthesis protein, CapA C2I28_22205 dae7f985681c7d52c61d08a36a60decd 368 SUPERFAMILY SSF56300 80 320 1.22E-41 T 15-10-2018 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 729 3.4E-261 T 15-10-2018 IPR004811 RelA/SpoT family GO:0015969 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Pfam PF02824 TGS domain 393 452 3.0E-22 T 15-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 SMART SM00954 240 350 1.6E-69 T 15-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Pfam PF13291 ACT domain 652 729 5.6E-22 T 15-10-2018 IPR002912 ACT domain C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Gene3D G3DSA:3.30.70.260 653 732 4.1E-18 T 15-10-2018 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 SUPERFAMILY SSF109604 10 196 4.71E-77 T 15-10-2018 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 SUPERFAMILY SSF81301 197 369 6.05E-67 T 15-10-2018 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Pfam PF13328 HD domain 31 180 9.7E-53 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 SUPERFAMILY SSF55021 655 731 4.58E-13 T 15-10-2018 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 SUPERFAMILY SSF81271 380 452 5.4E-22 T 15-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 SMART SM00471 46 158 1.4E-9 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Gene3D G3DSA:3.10.20.30 386 458 4.0E-31 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Gene3D G3DSA:3.30.460.10 198 329 7.1E-55 T 15-10-2018 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 2.8E-40 T 15-10-2018 IPR007685 RelA/SpoT GO:0015969 C2I28_04705 194f8c8906cd55ce68e808d9e75efaf1 732 Gene3D G3DSA:1.10.3210.10 1 196 2.1E-90 T 15-10-2018 C2I28_07815 3b9638875629aabb1232c143d0310a8c 280 Gene3D G3DSA:3.10.450.40 166 226 2.6E-7 T 15-10-2018 C2I28_07815 3b9638875629aabb1232c143d0310a8c 280 Gene3D G3DSA:3.10.450.40 45 110 8.4E-9 T 15-10-2018 C2I28_07815 3b9638875629aabb1232c143d0310a8c 280 Pfam PF03413 Peptidase propeptide and YPEB domain 55 109 1.5E-4 T 15-10-2018 IPR025711 PepSY domain C2I28_07815 3b9638875629aabb1232c143d0310a8c 280 Pfam PF03413 Peptidase propeptide and YPEB domain 172 225 2.2E-4 T 15-10-2018 IPR025711 PepSY domain C2I28_07815 3b9638875629aabb1232c143d0310a8c 280 Pfam PF03413 Peptidase propeptide and YPEB domain 230 279 0.0028 T 15-10-2018 IPR025711 PepSY domain C2I28_18505 c8ea813ca08b6310444f3ea73f3142cf 196 SUPERFAMILY SSF49329 52 194 1.83E-43 T 15-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_18505 c8ea813ca08b6310444f3ea73f3142cf 196 Gene3D G3DSA:2.60.40.200 48 196 4.7E-57 T 15-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_18505 c8ea813ca08b6310444f3ea73f3142cf 196 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 58 194 3.4E-42 T 15-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_18505 c8ea813ca08b6310444f3ea73f3142cf 196 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 183 194 - T 15-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 Gene3D G3DSA:1.10.287.130 282 413 3.2E-14 T 15-10-2018 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 SUPERFAMILY SSF47384 338 420 2.35E-14 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 Gene3D G3DSA:3.30.565.10 414 583 3.8E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 9.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 557 9.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 9.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 576 9.2E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 SMART SM00387 468 579 1.5E-33 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 355 413 8.7E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 578 1.0E-24 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 SUPERFAMILY SSF55874 412 579 2.1E-39 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09675 18ae33f64a78add07556d3de818ca16d 584 SMART SM00388 354 422 4.8E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 Gene3D G3DSA:3.40.50.720 1 247 8.8E-85 T 15-10-2018 C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.7E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.7E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.7E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.7E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.0E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.0E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.0E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 7.8E-67 T 15-10-2018 C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 SUPERFAMILY SSF51735 4 247 8.65E-86 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17165 f69ef85c31fdb967efa6e26e0ea42a46 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 199 0.0087 T 15-10-2018 C2I28_23875 bac778313a7a332c7bcb3c6c38850e47 152 SMART SM00871 1 149 1.2E-20 T 15-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I28_23875 bac778313a7a332c7bcb3c6c38850e47 152 SUPERFAMILY SSF55136 3 149 6.98E-23 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_23875 bac778313a7a332c7bcb3c6c38850e47 152 Pfam PF14526 Integron-associated effector binding protein 5 148 2.7E-24 T 15-10-2018 IPR029441 Integron-associated effector binding protein C2I28_23875 bac778313a7a332c7bcb3c6c38850e47 152 Gene3D G3DSA:3.20.80.10 1 150 9.1E-31 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_21095 63315d74525908ded7b30af7f2624af0 390 Gene3D G3DSA:1.20.1250.20 6 380 1.9E-58 T 15-10-2018 C2I28_21095 63315d74525908ded7b30af7f2624af0 390 Pfam PF07690 Major Facilitator Superfamily 16 233 5.3E-29 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_21095 63315d74525908ded7b30af7f2624af0 390 SUPERFAMILY SSF103473 12 382 9.81E-61 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21095 63315d74525908ded7b30af7f2624af0 390 PRINTS PR01035 Tetracycline resistance protein signature 134 156 6.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21095 63315d74525908ded7b30af7f2624af0 390 PRINTS PR01035 Tetracycline resistance protein signature 162 182 6.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21095 63315d74525908ded7b30af7f2624af0 390 PRINTS PR01035 Tetracycline resistance protein signature 21 37 6.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 18 520 4.6E-205 T 15-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 467 1.1E-145 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 Gene3D G3DSA:1.20.210.10 3 526 1.9E-197 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 SUPERFAMILY SSF81442 20 549 1.13E-174 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 425 446 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 191 210 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 1.3E-99 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14910 c835d4112b2110368629c3d2d6238b51 621 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 15-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23410 d8d364dd4d9ad395608d1f01dc4678dd 221 Pfam PF02310 B12 binding domain 93 183 3.8E-14 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_23410 d8d364dd4d9ad395608d1f01dc4678dd 221 Pfam PF02607 B12 binding domain 6 71 1.7E-9 T 15-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_23410 d8d364dd4d9ad395608d1f01dc4678dd 221 SUPERFAMILY SSF52242 89 191 2.09E-19 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_23410 d8d364dd4d9ad395608d1f01dc4678dd 221 Gene3D G3DSA:1.10.1240.10 5 78 1.5E-7 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_23410 d8d364dd4d9ad395608d1f01dc4678dd 221 SUPERFAMILY SSF47644 5 61 1.96E-5 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_23410 d8d364dd4d9ad395608d1f01dc4678dd 221 Gene3D G3DSA:3.40.50.280 88 211 9.5E-28 T 15-10-2018 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 SMART SM00865 207 324 1.1E-55 T 15-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 SMART SM00864 13 205 9.0E-120 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 Pfam PF12327 FtsZ family, C-terminal domain 222 315 3.2E-33 T 15-10-2018 IPR024757 Cell division protein FtsZ, C-terminal C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 371 39.843 T 15-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 15-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 PRINTS PR00423 Cell division protein FtsZ signature 189 211 9.1E-53 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 PRINTS PR00423 Cell division protein FtsZ signature 212 233 9.1E-53 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 PRINTS PR00423 Cell division protein FtsZ signature 126 147 9.1E-53 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 PRINTS PR00423 Cell division protein FtsZ signature 98 118 9.1E-53 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 Gene3D G3DSA:3.30.1330.20 221 326 7.4E-43 T 15-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 SUPERFAMILY SSF52490 12 208 5.89E-74 T 15-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 SUPERFAMILY SSF55307 204 318 2.29E-44 T 15-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 327 4.3E-142 T 15-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 Gene3D G3DSA:3.40.50.1440 4 220 1.2E-85 T 15-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 3.5E-46 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_02935 45f30835f99aa0b7a31d202ffc516e38 385 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 15-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 248 5.7E-29 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 Pfam PF04542 Sigma-70 region 2 28 100 1.7E-11 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 PIRSF PIRSF000770 5 253 4.3E-40 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 SUPERFAMILY SSF88659 171 250 4.3E-20 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 Pfam PF04545 Sigma-70, region 4 199 246 6.3E-15 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 Gene3D G3DSA:1.10.1740.10 15 97 8.2E-25 T 15-10-2018 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 Pfam PF04539 Sigma-70 region 3 107 185 9.7E-9 T 15-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 PRINTS PR00046 Major sigma-70 factor signature 79 87 3.4E-9 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 PRINTS PR00046 Major sigma-70 factor signature 234 245 3.4E-9 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 PRINTS PR00046 Major sigma-70 factor signature 219 234 3.4E-9 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 PRINTS PR00046 Major sigma-70 factor signature 55 68 3.4E-9 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 PRINTS PR00046 Major sigma-70 factor signature 202 214 3.4E-9 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 28 249 4.2E-76 T 15-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 SUPERFAMILY SSF88946 6 100 2.51E-24 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 Gene3D G3DSA:1.20.140.160 99 252 2.0E-40 T 15-10-2018 C2I28_02400 ba729a78eb835062ef2093aa3386e96c 253 SUPERFAMILY SSF88659 101 172 2.66E-10 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 Gene3D G3DSA:3.30.70.20 182 256 1.5E-5 T 15-10-2018 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.285 T 15-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 SMART SM00567 E-Z type HEAT repeats 330 359 2.2E-4 T 15-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 SMART SM00567 E-Z type HEAT repeats 298 327 9.2 T 15-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 342 2.8E-131 T 15-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 Gene3D G3DSA:1.25.10.10 292 377 9.1E-13 T 15-10-2018 IPR011989 Armadillo-like helical C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 Pfam PF13646 HEAT repeats 300 366 1.3E-12 T 15-10-2018 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 6.4E-20 T 15-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 7.5E-16 T 15-10-2018 C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 SUPERFAMILY SSF48371 296 373 1.1E-12 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_10335 df2810570afbd0e52fb2bffe5b814fd9 378 SUPERFAMILY SSF54862 164 250 1.97E-15 T 15-10-2018 C2I28_21620 0e4df6e936593d1d10403b8ccdff8a84 303 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_21620 0e4df6e936593d1d10403b8ccdff8a84 303 Pfam PF00005 ABC transporter 22 162 1.3E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_21620 0e4df6e936593d1d10403b8ccdff8a84 303 SMART SM00382 30 211 4.2E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_21620 0e4df6e936593d1d10403b8ccdff8a84 303 Gene3D G3DSA:3.40.50.300 1 232 1.3E-60 T 15-10-2018 C2I28_21620 0e4df6e936593d1d10403b8ccdff8a84 303 SUPERFAMILY SSF52540 3 231 8.25E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 Gene3D G3DSA:3.30.70.1560 123 215 1.3E-60 T 15-10-2018 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 SUPERFAMILY SSF55120 45 236 1.51E-48 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 Pfam PF01479 S4 domain 2 48 3.2E-16 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 SUPERFAMILY SSF55174 2 67 2.75E-16 T 15-10-2018 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 SMART SM00363 2 59 1.2E-15 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 Gene3D G3DSA:3.30.70.580 63 223 1.3E-60 T 15-10-2018 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 15-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 Gene3D G3DSA:3.10.290.10 1 57 1.5E-23 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 2.9E-53 T 15-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 C2I28_03425 c830f23e092a38fbc6d9f11fe19ee618 241 Pfam PF00849 RNA pseudouridylate synthase 62 195 1.0E-24 T 15-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_24385 f55b14d7dfd9ff7446bf4d5035ef7b68 100 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 12 26 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24385 f55b14d7dfd9ff7446bf4d5035ef7b68 100 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 45 58 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24385 f55b14d7dfd9ff7446bf4d5035ef7b68 100 Pfam PF00741 Gas vesicle protein 11 49 4.5E-16 T 15-10-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 C2I28_23860 b7be7516e05a720b224f8021e452180e 332 SUPERFAMILY SSF51735 121 295 1.43E-50 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_23860 b7be7516e05a720b224f8021e452180e 332 Gene3D G3DSA:3.90.180.10 13 328 4.8E-137 T 15-10-2018 C2I28_23860 b7be7516e05a720b224f8021e452180e 332 Pfam PF16884 N-terminal domain of oxidoreductase 4 110 2.4E-40 T 15-10-2018 C2I28_23860 b7be7516e05a720b224f8021e452180e 332 Pfam PF00107 Zinc-binding dehydrogenase 155 288 5.0E-24 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_23860 b7be7516e05a720b224f8021e452180e 332 SUPERFAMILY SSF50129 2 140 1.01E-40 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_23860 b7be7516e05a720b224f8021e452180e 332 SMART SM00829 15 328 6.5E-5 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_23860 b7be7516e05a720b224f8021e452180e 332 Gene3D G3DSA:3.40.50.720 124 300 4.8E-137 T 15-10-2018 C2I28_22985 564af6d195abc41f56783595052895a6 377 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 185 1.1E-28 T 15-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 C2I28_22985 564af6d195abc41f56783595052895a6 377 Gene3D G3DSA:3.40.50.2000 188 350 4.2E-20 T 15-10-2018 C2I28_22985 564af6d195abc41f56783595052895a6 377 SUPERFAMILY SSF53756 56 353 1.26E-29 T 15-10-2018 C2I28_22985 564af6d195abc41f56783595052895a6 377 Pfam PF00534 Glycosyl transferases group 1 220 345 4.8E-8 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_24090 427cf9c2c37edc5e8cbd29508345f053 241 Pfam PF03591 AzlC protein 26 166 2.9E-38 T 15-10-2018 IPR011606 Branched-chain amino acid transport, permease C2I28_11025 636bae68463a53b61d1167fdd0515afe 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 1.8E-16 T 15-10-2018 IPR025302 Domain of unknown function DUF4162 C2I28_11025 636bae68463a53b61d1167fdd0515afe 299 SMART SM00382 27 209 2.7E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11025 636bae68463a53b61d1167fdd0515afe 299 Gene3D G3DSA:3.40.50.300 1 229 1.4E-59 T 15-10-2018 C2I28_11025 636bae68463a53b61d1167fdd0515afe 299 SUPERFAMILY SSF52540 3 223 7.99E-59 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11025 636bae68463a53b61d1167fdd0515afe 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_11025 636bae68463a53b61d1167fdd0515afe 299 Pfam PF00005 ABC transporter 19 158 1.6E-28 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Pfam PF07724 AAA domain (Cdc48 subfamily) 442 608 1.3E-53 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 SMART SM01086 614 702 1.5E-30 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 SUPERFAMILY SSF52540 392 681 1.35E-78 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 213 225 - T 15-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 554 568 2.1E-36 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 447 465 2.1E-36 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 521 539 2.1E-36 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 492 510 2.1E-36 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 477 495 - T 15-10-2018 IPR028299 ClpA/B, conserved site 2 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 614 685 1.3E-22 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 SMART SM00382 443 615 8.6E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 SMART SM00382 118 261 8.8E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Pfam PF02151 UvrB/uvrC motif 334 367 2.6E-5 T 15-10-2018 IPR001943 UVR domain GO:0005515 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Gene3D G3DSA:3.40.50.300 72 260 1.4E-65 T 15-10-2018 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Gene3D G3DSA:1.10.8.60 614 704 1.7E-25 T 15-10-2018 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Gene3D G3DSA:4.10.860.10 326 376 3.1E-37 T 15-10-2018 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 SUPERFAMILY SSF52540 80 378 4.93E-70 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Gene3D G3DSA:1.10.8.60 263 383 3.1E-37 T 15-10-2018 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Gene3D G3DSA:3.40.50.300 396 613 5.1E-84 T 15-10-2018 C2I28_14375 1113d96b5cd9e222da03a1c08a9383e9 704 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 123 254 1.8E-12 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_02800 679f3fde652a4458f834e8af1db57f52 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 8.0E-88 T 15-10-2018 IPR005229 Conserved hypothetical protein CHP00255 C2I28_02800 679f3fde652a4458f834e8af1db57f52 291 Pfam PF03755 YicC-like family, N-terminal region 2 155 1.6E-46 T 15-10-2018 IPR013527 YicC-like, N-terminal C2I28_02800 679f3fde652a4458f834e8af1db57f52 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 6.6E-35 T 15-10-2018 IPR013551 Domain of unknown function DUF1732 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 SUPERFAMILY SSF51905 1 305 3.3E-23 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 224 238 2.4E-7 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 272 2.4E-7 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 167 2.4E-7 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.4E-7 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 Gene3D G3DSA:3.50.50.100 1 353 2.0E-76 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 283 1.4E-35 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.7E-8 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 223 239 3.7E-8 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 3.7E-8 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 3.7E-8 T 15-10-2018 C2I28_06410 e13165c788a4aa36270b600bb51a733b 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 3.7E-8 T 15-10-2018 C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 SMART SM00448 1 112 4.1E-43 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 SMART SM00862 144 219 2.1E-21 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 Gene3D G3DSA:1.10.10.10 121 221 5.8E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 SUPERFAMILY SSF52172 1 172 6.83E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 Gene3D G3DSA:3.40.50.2300 1 120 9.3E-39 T 15-10-2018 C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 2.5E-21 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_09080 f6c8f73e37d8995c0d019b09b3827407 225 Pfam PF00072 Response regulator receiver domain 3 112 5.7E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_11200 87452ee73ff1cefe935f9ab1befd6dd6 243 SUPERFAMILY SSF56281 1 242 9.17E-56 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_11200 87452ee73ff1cefe935f9ab1befd6dd6 243 Gene3D G3DSA:3.60.15.10 1 243 3.2E-88 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_11200 87452ee73ff1cefe935f9ab1befd6dd6 243 SMART SM00849 18 211 1.3E-11 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_11200 87452ee73ff1cefe935f9ab1befd6dd6 243 Pfam PF12706 Beta-lactamase superfamily domain 31 211 3.0E-21 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 SMART SM01003 4 136 1.5E-77 T 15-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 SUPERFAMILY SSF52283 1 360 1.62E-64 T 15-10-2018 C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 PIRSF PIRSF000183 1 371 1.5E-190 T 15-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 8.4E-47 T 15-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 Gene3D G3DSA:3.40.50.720 129 305 8.7E-141 T 15-10-2018 C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 9.2E-186 T 15-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 SMART SM01002 148 297 1.1E-90 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 9.0E-83 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 15-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 Gene3D G3DSA:3.40.50.720 3 353 8.7E-141 T 15-10-2018 C2I28_07640 39b60ff9657523cb5e4397101e3395b4 377 SUPERFAMILY SSF51735 136 303 1.82E-49 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 15 442 3.1E-203 T 15-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 SUPERFAMILY SSF53686 76 443 1.7E-55 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 Gene3D G3DSA:3.40.50.1100 29 442 4.7E-193 T 15-10-2018 C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 452 234.802 T 15-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 Gene3D G3DSA:3.40.50.1100 121 243 4.7E-193 T 15-10-2018 C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 113 127 - T 15-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I28_18230 a9d65bfe8f33dad1ace06082c4f3747e 452 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 83 401 5.0E-54 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 SUPERFAMILY SSF53800 3 308 1.96E-88 T 15-10-2018 C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 Gene3D G3DSA:3.40.50.1400 148 289 1.3E-108 T 15-10-2018 C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 ProSitePatterns PS00534 Ferrochelatase signature. 178 196 - T 15-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 TIGRFAM TIGR00109 hemH: ferrochelatase 2 307 3.0E-99 T 15-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 32.002 T 15-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 Pfam PF00762 Ferrochelatase 7 307 7.9E-85 T 15-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 C2I28_11160 15f9f0e5e017f06e07c2d54cc188ece1 310 Gene3D G3DSA:3.40.50.1400 8 304 1.3E-108 T 15-10-2018 C2I28_04115 caf398c5c3f7e8e30eede1ed75a055ab 269 Pfam PF00005 ABC transporter 38 194 2.9E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_04115 caf398c5c3f7e8e30eede1ed75a055ab 269 SUPERFAMILY SSF52540 13 255 1.69E-61 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04115 caf398c5c3f7e8e30eede1ed75a055ab 269 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 23 269 1.0E-125 T 15-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 C2I28_04115 caf398c5c3f7e8e30eede1ed75a055ab 269 Gene3D G3DSA:3.40.50.300 21 267 2.2E-64 T 15-10-2018 C2I28_04115 caf398c5c3f7e8e30eede1ed75a055ab 269 SMART SM00382 47 241 6.0E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04115 caf398c5c3f7e8e30eede1ed75a055ab 269 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SUPERFAMILY SSF54106 32 73 3.27E-10 T 15-10-2018 C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SUPERFAMILY SSF54106 162 205 1.29E-10 T 15-10-2018 C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Gene3D G3DSA:3.90.1720.10 230 348 2.7E-40 T 15-10-2018 C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SUPERFAMILY SSF54001 224 346 5.64E-40 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Gene3D G3DSA:3.10.350.10 91 145 2.0E-18 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Gene3D G3DSA:3.10.350.10 158 212 2.4E-18 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Pfam PF01476 LysM domain 96 137 1.5E-12 T 15-10-2018 IPR018392 LysM domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Pfam PF01476 LysM domain 163 204 1.5E-12 T 15-10-2018 IPR018392 LysM domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Pfam PF01476 LysM domain 32 73 2.9E-14 T 15-10-2018 IPR018392 LysM domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Pfam PF00877 NlpC/P60 family 243 344 4.7E-28 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SMART SM00257 30 73 9.7E-16 T 15-10-2018 IPR018392 LysM domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SMART SM00257 95 138 2.8E-16 T 15-10-2018 IPR018392 LysM domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SMART SM00257 162 205 5.8E-16 T 15-10-2018 IPR018392 LysM domain C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 SUPERFAMILY SSF54106 95 137 1.07E-11 T 15-10-2018 C2I28_07240 e0a499f50a44c1326d989efa935c92b8 348 Gene3D G3DSA:3.10.350.10 20 89 1.8E-17 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_00375 dd4669013599ac55687142094a5df2f7 235 SUPERFAMILY SSF51735 6 221 7.78E-57 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_00375 dd4669013599ac55687142094a5df2f7 235 Gene3D G3DSA:3.40.50.720 2 235 4.1E-69 T 15-10-2018 C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.2E-28 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.2E-28 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-28 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.2E-28 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.2E-28 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.0E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.0E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.0E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_00375 dd4669013599ac55687142094a5df2f7 235 Pfam PF00106 short chain dehydrogenase 6 198 2.7E-49 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 Gene3D G3DSA:2.30.170.50 1 66 1.5E-31 T 15-10-2018 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 6.6E-22 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.6E-22 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 6.6E-22 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 1.7E-30 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 Pfam PF01197 Ribosomal protein L31 1 64 3.0E-31 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 26.686 T 15-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_07430 7ea507007afbd9694984d05d8f3ff852 66 SUPERFAMILY SSF143800 1 65 1.02E-25 T 15-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00097 Anthranilate synthase component II signature 327 340 1.2E-6 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00097 Anthranilate synthase component II signature 214 223 1.2E-6 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00097 Anthranilate synthase component II signature 241 252 1.2E-6 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 SMART SM01097 1 131 6.3E-88 T 15-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 SUPERFAMILY SSF52317 140 355 3.25E-57 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 356 49.017 T 15-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 Pfam PF00117 Glutamine amidotransferase class-I 174 350 1.2E-47 T 15-10-2018 IPR017926 Glutamine amidotransferase C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 7.1E-12 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 7.1E-12 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 7.1E-12 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 SUPERFAMILY SSF52021 2 145 2.88E-57 T 15-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 Gene3D G3DSA:3.50.30.20 2 148 5.2E-57 T 15-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 Gene3D G3DSA:3.40.50.880 165 360 3.1E-35 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 1.8E-36 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 1.8E-36 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 1.8E-36 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 1.8E-36 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 1.8E-36 T 15-10-2018 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 129 1.6E-52 T 15-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02840 99bcc99e47bdd5a21fedbbafa6ac077a 361 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 353 1.9E-148 T 15-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_07595 9fdef743a0791ec502e1a059871c12b6 140 Gene3D G3DSA:1.10.10.2520 8 92 7.7E-12 T 15-10-2018 C2I28_07595 9fdef743a0791ec502e1a059871c12b6 140 Pfam PF07486 Cell Wall Hydrolase 25 129 1.2E-18 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 Pfam PF00571 CBS domain 212 269 1.8E-7 T 15-10-2018 IPR000644 CBS domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 Pfam PF00571 CBS domain 284 333 6.1E-6 T 15-10-2018 IPR000644 CBS domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 Gene3D G3DSA:3.10.580.10 190 342 2.3E-50 T 15-10-2018 C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 SMART SM01091 349 426 3.1E-19 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 Gene3D G3DSA:3.30.465.10 343 424 4.9E-17 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 Pfam PF03471 Transporter associated domain 350 424 4.9E-17 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 SUPERFAMILY SSF54631 199 336 1.39E-31 T 15-10-2018 C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 Pfam PF01595 Domain of unknown function DUF21 2 196 4.9E-49 T 15-10-2018 IPR002550 CNNM, transmembrane domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 SMART SM00116 220 269 7.1E-4 T 15-10-2018 IPR000644 CBS domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 SMART SM00116 285 333 4.5 T 15-10-2018 IPR000644 CBS domain C2I28_01515 2f7a0730e9743b877bbf0c107d6a5494 449 SUPERFAMILY SSF56176 347 431 3.27E-17 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_24790 a15c72e681a0c8b6bffeb22ef455886c 208 Pfam PF00881 Nitroreductase family 11 188 4.3E-32 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_24790 a15c72e681a0c8b6bffeb22ef455886c 208 Gene3D G3DSA:3.40.109.10 1 208 8.9E-60 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_24790 a15c72e681a0c8b6bffeb22ef455886c 208 SUPERFAMILY SSF55469 4 207 2.75E-58 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_04415 f66e3135c71a0d9c2d315203a8d3699c 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 7.2E-30 T 15-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04415 f66e3135c71a0d9c2d315203a8d3699c 88 Pfam PF01649 Ribosomal protein S20 2 84 1.9E-27 T 15-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04415 f66e3135c71a0d9c2d315203a8d3699c 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 88 1.0E-22 T 15-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04415 f66e3135c71a0d9c2d315203a8d3699c 88 SUPERFAMILY SSF46992 3 86 6.02E-30 T 15-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04415 f66e3135c71a0d9c2d315203a8d3699c 88 Gene3D G3DSA:1.20.58.110 1 87 3.3E-30 T 15-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04415 f66e3135c71a0d9c2d315203a8d3699c 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.163 T 15-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 15-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 502 515 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 440 451 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 280 293 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 204 217 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 294 307 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 147 160 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 171 179 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 218 233 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 PRINTS PR00415 Aconitase family signature 374 388 2.9E-41 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 Pfam PF00694 Aconitase C-terminal domain 701 828 1.0E-45 T 15-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 Gene3D G3DSA:1.10.1440.20 600 660 5.3E-23 T 15-10-2018 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 15-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 900 0.0 T 15-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 SUPERFAMILY SSF53732 5 635 1.1E-224 T 15-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 SUPERFAMILY SSF52016 640 899 4.91E-87 T 15-10-2018 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 Gene3D G3DSA:3.30.499.20 7 374 8.0E-158 T 15-10-2018 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 Pfam PF00330 Aconitase family (aconitate hydratase) 77 571 4.0E-176 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 Gene3D G3DSA:3.20.19.10 664 901 1.1E-104 T 15-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 C2I28_20900 8dc231775f77e9ddc590db051d3b068b 906 Gene3D G3DSA:3.30.499.10 375 599 1.1E-100 T 15-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 1.1E-25 T 15-10-2018 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 1.1E-25 T 15-10-2018 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 1.1E-25 T 15-10-2018 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 1.1E-25 T 15-10-2018 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 SUPERFAMILY SSF46548 2 163 6.28E-35 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 493 2.6E-249 T 15-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 140 7.0E-21 T 15-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 Gene3D G3DSA:3.50.50.60 152 285 9.0E-36 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 Gene3D G3DSA:1.10.1060.10 9 151 4.2E-19 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 475 1.4E-26 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 Gene3D G3DSA:3.50.50.60 286 487 1.1E-15 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18300 9c1a9b208720eb4174631cf41ff9a087 493 SUPERFAMILY SSF51971 151 421 2.35E-61 T 15-10-2018 C2I28_13795 377a3ed086272c72038058b00414df13 250 Gene3D G3DSA:3.20.20.140 1 250 5.2E-57 T 15-10-2018 C2I28_13795 377a3ed086272c72038058b00414df13 250 PIRSF PIRSF016557 1 250 1.7E-55 T 15-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 C2I28_27125 0f22e25b303a26d0697782b1340f698c 863 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 185 421 2.1E-19 T 15-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 C2I28_27125 0f22e25b303a26d0697782b1340f698c 863 SUPERFAMILY SSF52540 184 683 5.31E-21 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_27125 0f22e25b303a26d0697782b1340f698c 863 Pfam PF12696 TraM recognition site of TraD and TraG 560 676 2.2E-30 T 15-10-2018 IPR032689 TraD/TraG, TraM recognition site C2I28_27125 0f22e25b303a26d0697782b1340f698c 863 Gene3D G3DSA:3.40.50.300 490 706 2.4E-32 T 15-10-2018 C2I28_26275 0f22e25b303a26d0697782b1340f698c 863 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 185 421 2.1E-19 T 15-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 C2I28_26275 0f22e25b303a26d0697782b1340f698c 863 SUPERFAMILY SSF52540 184 683 5.31E-21 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26275 0f22e25b303a26d0697782b1340f698c 863 Pfam PF12696 TraM recognition site of TraD and TraG 560 676 2.2E-30 T 15-10-2018 IPR032689 TraD/TraG, TraM recognition site C2I28_26275 0f22e25b303a26d0697782b1340f698c 863 Gene3D G3DSA:3.40.50.300 490 706 2.4E-32 T 15-10-2018 C2I28_27225 0f22e25b303a26d0697782b1340f698c 863 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 185 421 2.1E-19 T 15-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 C2I28_27225 0f22e25b303a26d0697782b1340f698c 863 SUPERFAMILY SSF52540 184 683 5.31E-21 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_27225 0f22e25b303a26d0697782b1340f698c 863 Pfam PF12696 TraM recognition site of TraD and TraG 560 676 2.2E-30 T 15-10-2018 IPR032689 TraD/TraG, TraM recognition site C2I28_27225 0f22e25b303a26d0697782b1340f698c 863 Gene3D G3DSA:3.40.50.300 490 706 2.4E-32 T 15-10-2018 C2I28_26375 0f22e25b303a26d0697782b1340f698c 863 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 185 421 2.1E-19 T 15-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 C2I28_26375 0f22e25b303a26d0697782b1340f698c 863 SUPERFAMILY SSF52540 184 683 5.31E-21 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26375 0f22e25b303a26d0697782b1340f698c 863 Pfam PF12696 TraM recognition site of TraD and TraG 560 676 2.2E-30 T 15-10-2018 IPR032689 TraD/TraG, TraM recognition site C2I28_26375 0f22e25b303a26d0697782b1340f698c 863 Gene3D G3DSA:3.40.50.300 490 706 2.4E-32 T 15-10-2018 C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 4.2E-110 T 15-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.21 T 15-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 SUPERFAMILY SSF56808 6 225 5.1E-86 T 15-10-2018 IPR023674 Ribosomal protein L1-like C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 8.3E-58 T 15-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 Gene3D G3DSA:3.30.190.20 21 225 3.0E-87 T 15-10-2018 C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 Gene3D G3DSA:3.40.50.790 68 159 3.0E-87 T 15-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 PIRSF PIRSF002155 1 227 1.0E-84 T 15-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08625 bea583c6b6cf52f2438b2aae343daed5 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 15-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 SUPERFAMILY SSF53474 13 277 1.88E-65 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 1.7E-10 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.7E-10 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.7E-10 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 1.7E-10 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 7.8E-12 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 7.8E-12 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 7.8E-12 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 Pfam PF00561 alpha/beta hydrolase fold 25 258 2.5E-29 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00090 a8342e31955517e79c619cf78a5e7e15 278 Gene3D G3DSA:3.40.50.1820 1 277 2.2E-93 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_18710 b8df575adeeb774459c5e31d2fef87aa 180 Gene3D G3DSA:3.40.630.30 1 179 3.1E-35 T 15-10-2018 C2I28_18710 b8df575adeeb774459c5e31d2fef87aa 180 Pfam PF13302 Acetyltransferase (GNAT) domain 13 149 1.6E-18 T 15-10-2018 IPR000182 GNAT domain C2I28_18710 b8df575adeeb774459c5e31d2fef87aa 180 SUPERFAMILY SSF55729 6 173 1.42E-31 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_04375 12928b8ca1184752093897a81957b108 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 372 41.878 T 15-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 C2I28_04375 12928b8ca1184752093897a81957b108 376 SUPERFAMILY SSF49493 112 262 1.83E-20 T 15-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 C2I28_04375 12928b8ca1184752093897a81957b108 376 Pfam PF01556 DnaJ C terminal domain 118 335 4.8E-45 T 15-10-2018 IPR002939 Chaperone DnaJ, C-terminal C2I28_04375 12928b8ca1184752093897a81957b108 376 Gene3D G3DSA:1.10.287.110 1 110 2.2E-38 T 15-10-2018 IPR036869 Chaperone J-domain superfamily C2I28_04375 12928b8ca1184752093897a81957b108 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 15-10-2018 IPR018253 DnaJ domain, conserved site C2I28_04375 12928b8ca1184752093897a81957b108 376 Gene3D G3DSA:2.60.260.20 256 366 9.3E-32 T 15-10-2018 C2I28_04375 12928b8ca1184752093897a81957b108 376 Pfam PF00684 DnaJ central domain 145 209 2.6E-15 T 15-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 C2I28_04375 12928b8ca1184752093897a81957b108 376 Pfam PF00226 DnaJ domain 5 66 9.1E-26 T 15-10-2018 IPR001623 DnaJ domain C2I28_04375 12928b8ca1184752093897a81957b108 376 SUPERFAMILY SSF57938 132 213 9.16E-20 T 15-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily C2I28_04375 12928b8ca1184752093897a81957b108 376 SUPERFAMILY SSF46565 1 102 1.02E-35 T 15-10-2018 IPR036869 Chaperone J-domain superfamily C2I28_04375 12928b8ca1184752093897a81957b108 376 SUPERFAMILY SSF49493 260 346 1.57E-25 T 15-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 C2I28_04375 12928b8ca1184752093897a81957b108 376 Gene3D G3DSA:2.60.260.20 115 251 1.2E-37 T 15-10-2018 C2I28_04375 12928b8ca1184752093897a81957b108 376 SMART SM00271 4 61 1.7E-30 T 15-10-2018 IPR001623 DnaJ domain C2I28_04375 12928b8ca1184752093897a81957b108 376 PRINTS PR00625 DnaJ domain signature 41 61 6.8E-30 T 15-10-2018 IPR001623 DnaJ domain C2I28_04375 12928b8ca1184752093897a81957b108 376 PRINTS PR00625 DnaJ domain signature 7 25 6.8E-30 T 15-10-2018 IPR001623 DnaJ domain C2I28_04375 12928b8ca1184752093897a81957b108 376 PRINTS PR00625 DnaJ domain signature 61 80 6.8E-30 T 15-10-2018 IPR001623 DnaJ domain C2I28_04375 12928b8ca1184752093897a81957b108 376 PRINTS PR00625 DnaJ domain signature 25 40 6.8E-30 T 15-10-2018 IPR001623 DnaJ domain C2I28_04375 12928b8ca1184752093897a81957b108 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 2.1E-143 T 15-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 C2I28_04375 12928b8ca1184752093897a81957b108 376 Gene3D G3DSA:2.10.230.10 145 209 1.2E-37 T 15-10-2018 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 325 8.4E-14 T 15-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 Gene3D G3DSA:3.20.20.70 21 329 3.3E-105 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 Pfam PF04055 Radical SAM superfamily 69 223 2.9E-13 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 SMART SM00876 236 326 3.8E-35 T 15-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 PIRSF PIRSF001619 3 331 1.8E-123 T 15-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 SMART SM00729 60 268 4.6E-33 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 TIGRFAM TIGR00433 bioB: biotin synthase 33 325 1.5E-118 T 15-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 SUPERFAMILY SSF102114 20 327 1.06E-71 T 15-10-2018 C2I28_10445 26d31768ea7a6b97c82b506bbae1f41f 331 Hamap MF_01694 Biotin synthase [bioB]. 20 327 39.984 T 15-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 Pfam PF02803 Thiolase, C-terminal domain 271 392 3.1E-50 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 Gene3D G3DSA:3.40.47.10 127 391 5.7E-159 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 2.2E-147 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 15-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 15-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 SUPERFAMILY SSF53901 5 270 2.97E-80 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 15-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 SUPERFAMILY SSF53901 272 392 5.99E-46 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 PIRSF PIRSF000429 1 394 4.5E-137 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 Pfam PF00108 Thiolase, N-terminal domain 5 263 5.0E-88 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_17245 502af89621ff4159b97448d72ed50a3a 395 Gene3D G3DSA:3.40.47.10 7 277 5.7E-159 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_05065 d90c1c13951540800ef9fb7b1ad26a32 197 Gene3D G3DSA:3.90.950.10 1 196 4.6E-78 T 15-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I28_05065 d90c1c13951540800ef9fb7b1ad26a32 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 190 8.6E-66 T 15-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 C2I28_05065 d90c1c13951540800ef9fb7b1ad26a32 197 Pfam PF01725 Ham1 family 4 190 2.2E-60 T 15-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 C2I28_05065 d90c1c13951540800ef9fb7b1ad26a32 197 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 195 49.329 T 15-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 C2I28_05065 d90c1c13951540800ef9fb7b1ad26a32 197 SUPERFAMILY SSF52972 2 193 7.33E-71 T 15-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 Gene3D G3DSA:3.30.2130.10 257 409 1.2E-34 T 15-10-2018 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 SUPERFAMILY SSF55021 335 404 3.93E-16 T 15-10-2018 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 15-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 Pfam PF13840 ACT domain 338 398 7.5E-21 T 15-10-2018 IPR027795 CASTOR, ACT domain C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 PIRSF PIRSF000726 1 65 4.4E-9 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 PIRSF PIRSF000726 60 410 1.3E-91 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 403 3.6E-139 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 Gene3D G3DSA:3.40.1160.10 1 256 1.2E-84 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 SUPERFAMILY SSF55021 261 347 4.2E-15 T 15-10-2018 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 SUPERFAMILY SSF53633 2 247 2.09E-68 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 Pfam PF00696 Amino acid kinase family 2 235 2.9E-48 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_02255 62193f2032b970c59eaa6f4455c479c2 410 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 401 7.3E-93 T 15-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02240 c2ef2a05d4bf6f4099bb02c62085f333 250 Gene3D G3DSA:3.90.226.10 47 227 5.3E-29 T 15-10-2018 C2I28_02240 c2ef2a05d4bf6f4099bb02c62085f333 250 Pfam PF00574 Clp protease 49 225 4.1E-34 T 15-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I28_02240 c2ef2a05d4bf6f4099bb02c62085f333 250 SUPERFAMILY SSF52096 42 233 4.06E-37 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_06255 110be429ae07ab697785b5edec336615 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 9.4E-33 T 15-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like C2I28_01330 ca8b6390248adb071e130ebcc07654bb 456 Pfam PF00324 Amino acid permease 16 426 1.6E-92 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_01330 ca8b6390248adb071e130ebcc07654bb 456 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_01330 ca8b6390248adb071e130ebcc07654bb 456 PIRSF PIRSF006060 1 456 8.1E-72 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_01330 ca8b6390248adb071e130ebcc07654bb 456 Gene3D G3DSA:1.20.1740.10 8 454 2.2E-66 T 15-10-2018 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 Pfam PF00561 alpha/beta hydrolase fold 30 257 1.4E-21 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00412 Epoxide hydrolase signature 251 273 3.9E-6 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00412 Epoxide hydrolase signature 114 127 3.9E-6 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00412 Epoxide hydrolase signature 100 113 3.9E-6 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00412 Epoxide hydrolase signature 36 54 3.9E-6 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 SUPERFAMILY SSF53474 7 274 1.15E-58 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 Gene3D G3DSA:3.40.50.1820 3 280 7.1E-58 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 2.1E-13 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.1E-13 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 2.1E-13 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06305 1abcabc2b55f5197d155ea3dc4029e57 282 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.1E-13 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 237 252 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 175 188 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Gene3D G3DSA:1.10.8.60 323 398 2.0E-21 T 15-10-2018 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 SMART SM00448 20 130 2.3E-32 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Gene3D G3DSA:1.10.10.60 401 463 8.0E-17 T 15-10-2018 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Pfam PF02954 Bacterial regulatory protein, Fis family 419 458 1.4E-13 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 SMART SM00382 171 314 1.5E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Gene3D G3DSA:3.40.50.2300 21 137 1.3E-31 T 15-10-2018 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 SUPERFAMILY SSF52540 151 392 3.88E-67 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Gene3D G3DSA:3.40.50.300 138 322 9.0E-65 T 15-10-2018 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 SUPERFAMILY SSF46689 363 461 1.51E-14 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Pfam PF00072 Response regulator receiver domain 22 130 4.7E-25 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 SUPERFAMILY SSF52172 18 195 3.98E-36 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 Pfam PF00158 Sigma-54 interaction domain 152 317 1.6E-68 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 442 1.4E-13 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 442 462 1.4E-13 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_19265 f6bd67f9a9999f450a73af2ef5f64696 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 363 372 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_07115 59da59dc6e7178381182a555dbc254a2 184 SUPERFAMILY SSF46785 11 157 1.5E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_07115 59da59dc6e7178381182a555dbc254a2 184 Gene3D G3DSA:1.10.10.10 10 93 1.6E-23 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_07115 59da59dc6e7178381182a555dbc254a2 184 PIRSF PIRSF006707 3 184 6.9E-50 T 15-10-2018 IPR026282 DNA-binding protein, MJ1563 type C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 Gene3D G3DSA:3.40.640.10 153 371 3.2E-102 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 4.4E-14 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 Gene3D G3DSA:1.10.10.10 6 76 2.8E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 SUPERFAMILY SSF53383 91 479 3.84E-89 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 7.0E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 7.0E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 Gene3D G3DSA:3.90.1150.10 108 473 3.2E-102 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 SUPERFAMILY SSF46785 6 83 1.86E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 Pfam PF00155 Aminotransferase class I and II 121 468 1.4E-33 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_18780 4983654898a2677d5e5a98562152f5ef 480 SMART SM00345 17 76 7.6E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24820 c8427a76d9835897704426da16d7e21f 449 Pfam PF00535 Glycosyl transferase family 2 60 190 7.3E-23 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_24820 c8427a76d9835897704426da16d7e21f 449 Pfam PF02709 N-terminal domain of galactosyltransferase 261 314 8.0E-8 T 15-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 C2I28_24820 c8427a76d9835897704426da16d7e21f 449 SUPERFAMILY SSF53448 54 349 4.92E-46 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_24820 c8427a76d9835897704426da16d7e21f 449 Gene3D G3DSA:3.90.550.10 33 340 2.2E-55 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 Gene3D G3DSA:2.30.330.10 293 385 3.0E-35 T 15-10-2018 IPR036429 SpoA-like superfamily C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 Pfam PF04509 CheC-like family 49 85 3.3E-15 T 15-10-2018 IPR007597 CheC-like protein GO:0016787 C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 Pfam PF04509 CheC-like family 148 181 2.6E-15 T 15-10-2018 IPR007597 CheC-like protein GO:0016787 C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 305 375 2.3E-24 T 15-10-2018 IPR001543 Surface presentation of antigen (SpoA) C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 Gene3D G3DSA:3.40.1550.10 44 238 9.8E-56 T 15-10-2018 IPR028976 CheC-like superfamily C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 SUPERFAMILY SSF103039 44 234 2.44E-50 T 15-10-2018 IPR028976 CheC-like superfamily C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 SUPERFAMILY SSF101801 301 383 1.83E-24 T 15-10-2018 IPR036429 SpoA-like superfamily C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 PRINTS PR00956 Flagellar motor switch protein FliN signature 322 338 1.1E-28 T 15-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 PRINTS PR00956 Flagellar motor switch protein FliN signature 338 351 1.1E-28 T 15-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 PRINTS PR00956 Flagellar motor switch protein FliN signature 351 366 1.1E-28 T 15-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 PRINTS PR00956 Flagellar motor switch protein FliN signature 305 321 1.1E-28 T 15-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 C2I28_02470 e58046b77e95c4bbb9edb2a7d1b34a56 385 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 302 377 9.9E-31 T 15-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 Pfam PF13242 HAD-hyrolase-like 179 251 1.1E-21 T 15-10-2018 C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 PIRSF PIRSF000915 105 256 3.9E-36 T 15-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 PIRSF PIRSF000915 1 115 1.1E-27 T 15-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 Gene3D G3DSA:3.40.50.1000 6 242 1.6E-86 T 15-10-2018 IPR023214 HAD superfamily C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 6.1E-41 T 15-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 1.6E-119 T 15-10-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 107 6.4E-29 T 15-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 Gene3D G3DSA:3.40.50.1000 84 179 1.6E-86 T 15-10-2018 IPR023214 HAD superfamily C2I28_06455 9b1949a81a86e61ed984e48783f81215 256 SUPERFAMILY SSF56784 4 253 1.18E-74 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_17255 ab30cd1dade9e44c4ce9ce74188d7602 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 15-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I28_17255 ab30cd1dade9e44c4ce9ce74188d7602 260 SUPERFAMILY SSF52096 4 259 2.4E-84 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_17255 ab30cd1dade9e44c4ce9ce74188d7602 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 1.3E-66 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_17255 ab30cd1dade9e44c4ce9ce74188d7602 260 Gene3D G3DSA:3.90.226.10 2 201 7.3E-71 T 15-10-2018 C2I28_17255 ab30cd1dade9e44c4ce9ce74188d7602 260 Gene3D G3DSA:1.10.12.10 202 260 2.1E-22 T 15-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 248 8.4E-114 T 15-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 PRINTS PR00046 Major sigma-70 factor signature 203 215 4.2E-11 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 PRINTS PR00046 Major sigma-70 factor signature 61 74 4.2E-11 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 PRINTS PR00046 Major sigma-70 factor signature 220 235 4.2E-11 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 PRINTS PR00046 Major sigma-70 factor signature 85 93 4.2E-11 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 PRINTS PR00046 Major sigma-70 factor signature 235 246 4.2E-11 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 Gene3D G3DSA:1.10.10.10 179 252 7.5E-12 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 31 249 3.0E-87 T 15-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 248 4.5E-37 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 Gene3D G3DSA:1.10.10.10 106 160 1.3E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 SUPERFAMILY SSF88946 6 105 1.22E-33 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 Pfam PF04542 Sigma-70 region 2 38 104 1.1E-16 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 SUPERFAMILY SSF88659 109 184 1.4E-16 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 PIRSF PIRSF000770 5 253 4.9E-38 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 SUPERFAMILY SSF88659 171 252 1.42E-17 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 Pfam PF04545 Sigma-70, region 4 199 247 2.2E-15 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 Gene3D G3DSA:1.10.601.10 3 105 2.1E-27 T 15-10-2018 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 Pfam PF04539 Sigma-70 region 3 117 181 5.6E-14 T 15-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 C2I28_03520 343c765be7ca0fa18a2e8d9e4f7c56fc 253 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 SUPERFAMILY SSF56042 204 430 1.29E-58 T 15-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 3.8E-26 T 15-10-2018 IPR016188 PurM-like, N-terminal domain C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 9.9E-25 T 15-10-2018 IPR016188 PurM-like, N-terminal domain C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Gene3D G3DSA:3.30.1330.10 49 197 7.1E-136 T 15-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 SUPERFAMILY SSF56042 573 739 1.39E-34 T 15-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Gene3D G3DSA:3.90.650.10 34 362 7.1E-136 T 15-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Gene3D G3DSA:3.90.650.10 570 741 7.1E-36 T 15-10-2018 IPR036676 PurM-like, C-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Gene3D G3DSA:3.30.1330.10 389 565 7.6E-63 T 15-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 743 325.309 T 15-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 360 3.3E-34 T 15-10-2018 IPR010918 PurM-like, C-terminal domain C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 Pfam PF02769 AIR synthase related protein, C-terminal domain 576 712 3.0E-14 T 15-10-2018 IPR010918 PurM-like, C-terminal domain C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 SUPERFAMILY SSF55326 18 202 4.93E-51 T 15-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 SUPERFAMILY SSF55326 399 570 9.68E-60 T 15-10-2018 IPR036921 PurM-like, N-terminal domain superfamily C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 738 0.0 T 15-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09455 3dd639b4f3f0bd10dfed905a683cf87e 743 PIRSF PIRSF001587 7 742 0.0 T 15-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Gene3D G3DSA:2.40.30.10 207 336 3.0E-52 T 15-10-2018 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.999 T 15-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 147 1.1E-14 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 6.3E-34 T 15-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 5.7E-61 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 SUPERFAMILY SSF50447 204 303 1.08E-30 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 3.2E-232 T 15-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 15-10-2018 IPR031157 Tr-type G domain, conserved site C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 PRINTS PR00315 GTP-binding elongation factor signature 79 89 2.2E-24 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 PRINTS PR00315 GTP-binding elongation factor signature 132 141 2.2E-24 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.2E-24 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 PRINTS PR00315 GTP-binding elongation factor signature 59 67 2.2E-24 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 PRINTS PR00315 GTP-binding elongation factor signature 95 106 2.2E-24 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 SUPERFAMILY SSF50465 300 394 6.33E-35 T 15-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 2.7E-17 T 15-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Gene3D G3DSA:3.40.50.300 1 204 1.9E-69 T 15-10-2018 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 Gene3D G3DSA:2.40.30.10 340 394 1.2E-27 T 15-10-2018 C2I28_08675 bec2c0359708f9132ce62ed78d013306 396 SUPERFAMILY SSF52540 6 220 9.32E-64 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 5.6E-19 T 15-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 SUPERFAMILY SSF52540 1 212 3.84E-47 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.7E-81 T 15-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 PRINTS PR00094 Adenylate kinase signature 160 175 9.5E-34 T 15-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 PRINTS PR00094 Adenylate kinase signature 177 191 9.5E-34 T 15-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 PRINTS PR00094 Adenylate kinase signature 4 17 9.5E-34 T 15-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 PRINTS PR00094 Adenylate kinase signature 32 46 9.5E-34 T 15-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 PRINTS PR00094 Adenylate kinase signature 81 97 9.5E-34 T 15-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 Gene3D G3DSA:3.40.50.300 1 216 1.1E-84 T 15-10-2018 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.379 T 15-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 15-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 C2I28_08790 c68bdef636dbb9ac85f14160e05dee61 217 Pfam PF00406 Adenylate kinase 5 190 7.7E-62 T 15-10-2018 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 SUPERFAMILY SSF52540 32 594 2.48E-38 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 658 44.894 T 15-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Pfam PF12344 Ultra-violet resistance protein B 551 593 1.7E-22 T 15-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 SMART SM00487 9 425 7.7E-26 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Pfam PF00271 Helicase conserved C-terminal domain 440 544 3.7E-19 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 656 0.0 T 15-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Gene3D G3DSA:3.40.50.300 266 413 3.6E-54 T 15-10-2018 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 SMART SM00490 459 545 7.4E-20 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Pfam PF02151 UvrB/uvrC motif 624 657 1.6E-9 T 15-10-2018 IPR001943 UVR domain GO:0005515 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Gene3D G3DSA:3.40.50.300 414 595 6.6E-54 T 15-10-2018 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Pfam PF04851 Type III restriction enzyme, res subunit 14 138 1.2E-12 T 15-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 SUPERFAMILY SSF52540 3 414 3.93E-146 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 SUPERFAMILY SSF46600 614 657 4.58E-10 T 15-10-2018 IPR036876 UVR domain superfamily C2I28_06985 ed2b8a56023c22b4efc054aa227f0e76 659 Gene3D G3DSA:3.40.50.300 1 242 1.1E-84 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:3.20.20.70 516 820 1.5E-294 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:1.10.472.90 821 945 1.5E-294 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 116 4.0E-43 T 15-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SUPERFAMILY SSF51230 1070 1148 2.09E-22 T 15-10-2018 IPR011053 Single hybrid motif C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Pfam PF02436 Conserved carboxylase domain 831 1030 7.3E-77 T 15-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SUPERFAMILY SSF52440 6 119 5.97E-45 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:3.10.600.10 466 510 3.6E-9 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SUPERFAMILY SSF89000 836 1013 1.37E-58 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Pfam PF00682 HMGL-like 536 807 2.8E-28 T 15-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SUPERFAMILY SSF51569 528 839 7.33E-85 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:1.10.10.2790 946 981 1.5E-294 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SMART SM00878 348 455 1.9E-50 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:3.10.600.10 511 1063 1.5E-294 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 PIRSF PIRSF001594 3 1149 0.0 T 15-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Pfam PF00364 Biotin-requiring enzyme 1081 1147 1.9E-18 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 10 1148 0.0 T 15-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:3.30.470.130 2 463 3.1E-194 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SUPERFAMILY SSF56059 90 340 3.71E-67 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Pfam PF02785 Biotin carboxylase C-terminal domain 348 455 6.0E-32 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Gene3D G3DSA:2.40.50.100 1071 1148 4.8E-26 T 15-10-2018 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 122 328 4.4E-78 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 160 174 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_14890 07122f442b11cb11ebc7941bb434cf63 1149 SUPERFAMILY SSF51246 343 462 1.05E-37 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_22155 af57aaaed3b95211b117079d01923153 107 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 104 1.2E-41 T 15-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 C2I28_22155 af57aaaed3b95211b117079d01923153 107 SUPERFAMILY SSF103481 7 106 5.49E-10 T 15-10-2018 C2I28_22155 af57aaaed3b95211b117079d01923153 107 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 107 21.632 T 15-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 Gene3D G3DSA:3.40.50.300 4 332 4.0E-102 T 15-10-2018 C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 Pfam PF00005 ABC transporter 28 179 1.2E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 SUPERFAMILY SSF52540 6 251 5.81E-76 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 SMART SM00382 36 229 1.4E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 318 9.7E-29 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_15420 36d64c862e684e971aa0cd44d3dcf27e 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 298 2.3E-17 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 Gene3D G3DSA:1.20.1250.20 196 395 3.7E-66 T 15-10-2018 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 4 392 1.7E-131 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 Gene3D G3DSA:1.20.1250.20 2 195 1.1E-42 T 15-10-2018 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 Pfam PF01306 LacY proton/sugar symporter 3 397 2.2E-132 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 252 273 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 307 326 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 276 302 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 143 161 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 101 123 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 66 95 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 206 234 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 PRINTS PR00174 LacY proton/sugar symporter family signature 338 358 6.4E-74 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_00215 d6ba25850d476e078589aa81150a2a78 409 SUPERFAMILY SSF103473 4 402 3.79E-48 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_27525 30324be5bc7d66c93fa9275bcb353980 446 SUPERFAMILY SSF56176 8 201 2.1E-46 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_27525 30324be5bc7d66c93fa9275bcb353980 446 Gene3D G3DSA:3.40.462.20 203 398 8.8E-93 T 15-10-2018 C2I28_27525 30324be5bc7d66c93fa9275bcb353980 446 Pfam PF01565 FAD binding domain 32 166 8.8E-29 T 15-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I28_27525 30324be5bc7d66c93fa9275bcb353980 446 Gene3D G3DSA:3.30.43.10 7 86 4.0E-22 T 15-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I28_27525 30324be5bc7d66c93fa9275bcb353980 446 Pfam PF08031 Berberine and berberine like 399 443 1.6E-19 T 15-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 C2I28_27525 30324be5bc7d66c93fa9275bcb353980 446 Gene3D G3DSA:3.30.465.50 91 444 8.8E-93 T 15-10-2018 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 67 96 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 207 235 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 102 124 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 144 162 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 253 274 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 339 359 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 277 303 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 PRINTS PR00174 LacY proton/sugar symporter family signature 308 327 1.1E-88 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 Pfam PF01306 LacY proton/sugar symporter 5 402 2.0E-139 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 Gene3D G3DSA:1.20.1250.20 197 395 1.7E-63 T 15-10-2018 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 SUPERFAMILY SSF103473 8 401 4.84E-42 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 Gene3D G3DSA:1.20.1250.20 4 196 8.3E-42 T 15-10-2018 C2I28_15885 b8e571b67afbf3aa20cf517c77cfd2bd 413 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 7 393 2.1E-139 T 15-10-2018 IPR000576 LacY/RafB permease family GO:0005351|GO:0008643|GO:0016020 C2I28_22110 95641782a0e019f36dd75916185a8b37 316 Gene3D G3DSA:3.40.50.1360 57 316 4.4E-82 T 15-10-2018 C2I28_22110 95641782a0e019f36dd75916185a8b37 316 Pfam PF04198 Putative sugar-binding domain 62 312 2.8E-69 T 15-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 C2I28_22110 95641782a0e019f36dd75916185a8b37 316 SUPERFAMILY SSF88659 13 48 1.7E-6 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_22110 95641782a0e019f36dd75916185a8b37 316 Pfam PF13384 Homeodomain-like domain 13 51 1.9E-7 T 15-10-2018 C2I28_22110 95641782a0e019f36dd75916185a8b37 316 SUPERFAMILY SSF100950 62 314 5.23E-73 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_22110 95641782a0e019f36dd75916185a8b37 316 Gene3D G3DSA:1.10.10.60 2 54 2.1E-21 T 15-10-2018 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SUPERFAMILY SSF49313 749 833 1.43E-6 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SUPERFAMILY SSF49313 476 564 3.28E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 Pfam PF01345 Domain of unknown function DUF11 343 429 3.7E-11 T 15-10-2018 IPR001434 Domain of unknown function DUF11 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 Gene3D G3DSA:2.60.40.10 652 740 1.2E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 Gene3D G3DSA:2.60.40.10 742 832 4.3E-7 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 345 397 9.1E-15 T 15-10-2018 IPR001434 Domain of unknown function DUF11 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SUPERFAMILY SSF49313 567 655 4.28E-8 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SUPERFAMILY SSF49313 669 744 3.71E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SMART SM00112 492 565 1.8 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SMART SM00112 583 656 0.044 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_27715 3f1ed58aa13e02149c310884616687bf 835 SMART SM00112 674 747 0.53 T 15-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 C2I28_10115 3341204faa3fbbb89360f7c401436f96 178 SUPERFAMILY SSF159234 5 171 1.44E-29 T 15-10-2018 IPR035930 FomD-like superfamily C2I28_10115 3341204faa3fbbb89360f7c401436f96 178 Hamap MF_01568 UPF0374 protein . 1 176 49.548 T 15-10-2018 IPR016882 Uncharacterised protein family UPF0374 C2I28_10115 3341204faa3fbbb89360f7c401436f96 178 Pfam PF04167 Protein of unknown function (DUF402) 60 125 1.5E-16 T 15-10-2018 IPR007295 Domain of unknown function DUF402 C2I28_10115 3341204faa3fbbb89360f7c401436f96 178 Gene3D G3DSA:2.40.380.10 14 170 2.3E-10 T 15-10-2018 IPR035930 FomD-like superfamily C2I28_10115 3341204faa3fbbb89360f7c401436f96 178 PIRSF PIRSF028345 1 178 1.3E-78 T 15-10-2018 IPR016882 Uncharacterised protein family UPF0374 C2I28_22165 42c72877b954a8df4fe509edd4a70ba8 427 Gene3D G3DSA:3.40.190.10 146 417 1.2E-88 T 15-10-2018 C2I28_22165 42c72877b954a8df4fe509edd4a70ba8 427 SUPERFAMILY SSF53850 23 426 3.53E-68 T 15-10-2018 C2I28_22165 42c72877b954a8df4fe509edd4a70ba8 427 Gene3D G3DSA:3.40.190.10 60 363 1.2E-88 T 15-10-2018 C2I28_22165 42c72877b954a8df4fe509edd4a70ba8 427 Pfam PF13416 Bacterial extracellular solute-binding protein 59 365 6.1E-49 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 SUPERFAMILY SSF50129 318 360 2.83E-5 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 SUPERFAMILY SSF51735 157 331 4.76E-46 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 Gene3D G3DSA:3.90.180.10 7 359 3.9E-121 T 15-10-2018 C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 SMART SM00829 10 367 3.5E-7 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 153 1.2E-26 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 15-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 Gene3D G3DSA:3.40.50.720 172 309 3.9E-121 T 15-10-2018 C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 Pfam PF00107 Zinc-binding dehydrogenase 195 319 1.7E-27 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_19300 6101e4e3c8293c7572111b1a7a1ecacd 388 SUPERFAMILY SSF50129 1 191 6.63E-58 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 Pfam PF01336 OB-fold nucleic acid binding domain 60 137 1.4E-15 T 15-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 Gene3D G3DSA:2.40.50.140 6 146 2.8E-47 T 15-10-2018 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 Pfam PF00152 tRNA synthetases class II (D, K and N) 155 491 1.6E-84 T 15-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 SUPERFAMILY SSF50249 5 146 2.79E-45 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 493 2.3E-229 T 15-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 12 494 46.784 T 15-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 PIRSF PIRSF039101 2 494 4.5E-205 T 15-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 Gene3D G3DSA:3.30.930.10 147 491 1.3E-139 T 15-10-2018 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 190 200 4.9E-40 T 15-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 376 392 4.9E-40 T 15-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 206 222 4.9E-40 T 15-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 253 270 4.9E-40 T 15-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 235 248 4.9E-40 T 15-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_08505 b0eea20afff3ebdff36a766c673a8f41 494 SUPERFAMILY SSF55681 153 492 1.38E-125 T 15-10-2018 C2I28_13380 78dcd1a14639956e8fae29f5e252f715 283 Pfam PF06800 Sugar transport protein 4 280 2.9E-110 T 15-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 C2I28_13380 78dcd1a14639956e8fae29f5e252f715 283 SUPERFAMILY SSF103481 197 278 1.12E-5 T 15-10-2018 C2I28_13380 78dcd1a14639956e8fae29f5e252f715 283 SUPERFAMILY SSF103481 37 137 9.94E-8 T 15-10-2018 C2I28_13380 78dcd1a14639956e8fae29f5e252f715 283 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 282 5.4E-112 T 15-10-2018 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 PIRSF PIRSF016578 1 89 1.6E-4 T 15-10-2018 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 PIRSF PIRSF016578 134 381 2.0E-13 T 15-10-2018 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.3E-30 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 9.4E-52 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 Gene3D G3DSA:1.10.540.10 1 120 1.9E-34 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 SUPERFAMILY SSF47203 228 380 3.7E-58 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 Gene3D G3DSA:2.40.110.10 121 236 1.2E-40 T 15-10-2018 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 Gene3D G3DSA:1.20.140.10 237 381 3.6E-58 T 15-10-2018 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 3.0E-25 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_17220 025bb3409e549e8df1470102fe51c4b4 382 SUPERFAMILY SSF56645 3 243 2.49E-77 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_06010 8bf9b0fc8ecc004fa48cbb95ec65fd1a 473 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 114 465 1.7E-112 T 15-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 C2I28_06010 8bf9b0fc8ecc004fa48cbb95ec65fd1a 473 Pfam PF00425 chorismate binding enzyme 205 457 2.4E-78 T 15-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I28_06010 8bf9b0fc8ecc004fa48cbb95ec65fd1a 473 Gene3D G3DSA:3.60.120.10 3 468 4.0E-110 T 15-10-2018 IPR005801 ADC synthase GO:0009058 C2I28_06010 8bf9b0fc8ecc004fa48cbb95ec65fd1a 473 SUPERFAMILY SSF56322 29 466 3.14E-105 T 15-10-2018 IPR005801 ADC synthase GO:0009058 C2I28_06010 8bf9b0fc8ecc004fa48cbb95ec65fd1a 473 Hamap MF_01935 Isochorismate synthase MenF [menF]. 4 467 30.608 T 15-10-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 C2I28_00935 dc685472592925a23b454600799fbc2a 272 Pfam PF00494 Squalene/phytoene synthase 15 207 3.5E-22 T 15-10-2018 C2I28_00935 dc685472592925a23b454600799fbc2a 272 Gene3D G3DSA:1.10.600.10 4 272 8.3E-59 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_00935 dc685472592925a23b454600799fbc2a 272 SUPERFAMILY SSF48576 13 254 7.05E-41 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 SUPERFAMILY SSF46785 3 62 2.55E-10 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Gene3D G3DSA:1.10.10.10 2 62 7.2E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Gene3D G3DSA:3.30.930.10 71 277 1.1E-68 T 15-10-2018 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 325 2.4E-68 T 15-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 SUPERFAMILY SSF55681 73 277 3.48E-62 T 15-10-2018 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Gene3D G3DSA:2.30.30.100 280 326 5.1E-7 T 15-10-2018 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 11 77 3.3E-21 T 15-10-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 326 37.774 T 15-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 90 214 1.1E-19 T 15-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Pfam PF02237 Biotin protein ligase C terminal domain 280 326 1.2E-9 T 15-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_14990 bd27a91f1dc8cea091ed30698d6049e5 329 Pfam PF08279 HTH domain 6 60 4.4E-16 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_04035 cb33b6e75a421811372ce8eeae59df76 350 Gene3D G3DSA:3.30.450.90 2 108 2.1E-28 T 15-10-2018 C2I28_04035 cb33b6e75a421811372ce8eeae59df76 350 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 15-10-2018 IPR001482 Type II/IV secretion system protein C2I28_04035 cb33b6e75a421811372ce8eeae59df76 350 SUPERFAMILY SSF52540 4 282 8.26E-65 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04035 cb33b6e75a421811372ce8eeae59df76 350 SMART SM00382 136 258 0.003 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04035 cb33b6e75a421811372ce8eeae59df76 350 Gene3D G3DSA:3.40.50.300 110 323 1.2E-65 T 15-10-2018 C2I28_04035 cb33b6e75a421811372ce8eeae59df76 350 Pfam PF00437 Type II/IV secretion system protein 18 275 4.4E-69 T 15-10-2018 IPR001482 Type II/IV secretion system protein C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 SUPERFAMILY SSF110455 1 115 2.3E-35 T 15-10-2018 C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 176 3.4E-62 T 15-10-2018 IPR004466 Ribonuclease M5 GO:0043822 C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 178 32.818 T 15-10-2018 IPR004466 Ribonuclease M5 GO:0043822 C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 Pfam PF13662 Toprim domain 4 66 3.1E-8 T 15-10-2018 IPR006171 TOPRIM domain C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 Gene3D G3DSA:3.40.1360.20 1 120 4.9E-25 T 15-10-2018 C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 Pfam PF13331 Domain of unknown function (DUF4093) 93 176 7.2E-27 T 15-10-2018 IPR025156 Ribonuclease M5, C-terminal domain C2I28_08310 6231bf3b20aa49051af80dadb7683e92 187 SMART SM00493 4 77 2.8E-7 T 15-10-2018 IPR006171 TOPRIM domain C2I28_02985 9e8270b85480066d8fb801103a1b6cfd 119 Pfam PF04977 Septum formation initiator 43 118 5.4E-10 T 15-10-2018 IPR007060 Septum formation initiator FtsL/DivIC C2I28_02985 9e8270b85480066d8fb801103a1b6cfd 119 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 36 117 1.6E-18 T 15-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 C2I28_02985 9e8270b85480066d8fb801103a1b6cfd 119 Hamap MF_00910 Cell division protein FtsL [ftsL]. 36 118 14.4 T 15-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 15-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 PRINTS PR00107 Phosphocarrier protein signature 37 52 3.8E-16 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 PRINTS PR00107 Phosphocarrier protein signature 12 28 3.8E-16 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 PRINTS PR00107 Phosphocarrier protein signature 52 69 3.8E-16 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 80 6.0E-26 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 Pfam PF00381 PTS HPr component phosphorylation site 2 81 1.9E-28 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 SUPERFAMILY SSF55594 2 83 3.27E-26 T 15-10-2018 IPR035895 HPr-like superfamily C2I28_06865 10158bd7c7a853a23bd46356e8688e2e 84 Gene3D G3DSA:3.30.1340.10 1 84 2.6E-31 T 15-10-2018 IPR035895 HPr-like superfamily C2I28_16715 7949013c9d0e0b1452be15cdaf5eccb9 186 SUPERFAMILY SSF51182 3 170 4.66E-25 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_16715 7949013c9d0e0b1452be15cdaf5eccb9 186 Gene3D G3DSA:2.60.120.10 1 157 8.9E-39 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_16715 7949013c9d0e0b1452be15cdaf5eccb9 186 Pfam PF05995 Cysteine dioxygenase type I 46 152 1.4E-13 T 15-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 Gene3D G3DSA:3.20.20.450 1 228 1.6E-69 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 SUPERFAMILY SSF103190 262 399 3.69E-41 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 Pfam PF10388 EAL-domain associated signalling protein domain 239 403 1.1E-71 T 15-10-2018 IPR018842 YkuI, C-terminal C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 Pfam PF00563 EAL domain 15 235 5.7E-38 T 15-10-2018 IPR001633 EAL domain C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 SUPERFAMILY SSF141868 10 237 5.23E-50 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 Gene3D G3DSA:3.30.450.20 290 403 3.4E-47 T 15-10-2018 C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 Gene3D G3DSA:1.20.5.170 245 289 7.8E-10 T 15-10-2018 C2I28_14660 8ec74c15f4e57154fe52aa39571ce436 403 SMART SM00052 2 240 1.8E-37 T 15-10-2018 IPR001633 EAL domain C2I28_19890 340af6b4c87237f2c64f334593944676 293 SUPERFAMILY SSF51366 17 265 1.08E-68 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_19890 340af6b4c87237f2c64f334593944676 293 ProSitePatterns PS01235 PdxS/SNZ family signature. 204 222 - T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_19890 340af6b4c87237f2c64f334593944676 293 PIRSF PIRSF029271 1 293 1.3E-152 T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_19890 340af6b4c87237f2c64f334593944676 293 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 3 293 53.777 T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_19890 340af6b4c87237f2c64f334593944676 293 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 8 293 1.4E-156 T 15-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_19890 340af6b4c87237f2c64f334593944676 293 Gene3D G3DSA:3.20.20.70 1 293 3.1E-147 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_19890 340af6b4c87237f2c64f334593944676 293 Pfam PF01680 SOR/SNZ family 7 211 2.2E-105 T 15-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_15625 dfa6eeeae5d98da54bff8e0f1f298dd9 53 ProDom PD053407 YFHD 2 53 2.0E-5 T 15-10-2018 C2I28_15625 dfa6eeeae5d98da54bff8e0f1f298dd9 53 Pfam PF14151 YfhD-like protein 7 53 1.7E-16 T 15-10-2018 IPR025435 YfhD-like protein C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 Pfam PF00294 pfkB family carbohydrate kinase 15 317 7.7E-63 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 8 329 56.033 T 15-10-2018 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 269 282 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 Gene3D G3DSA:2.20.150.10 20 116 1.3E-95 T 15-10-2018 IPR023314 5-Dehydro-2-deoxygluconokinase-like superfamily KEGG: 00562+2.7.1.92 C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 SUPERFAMILY SSF53613 11 325 2.03E-71 T 15-10-2018 IPR029056 Ribokinase-like C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 Gene3D G3DSA:3.40.1190.20 15 304 1.3E-95 T 15-10-2018 IPR029056 Ribokinase-like C2I28_10600 6055cd5e1086679fe81f0a672a5090cb 335 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 12 325 2.0E-124 T 15-10-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 SUPERFAMILY SSF46785 1 109 1.91E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 Gene3D G3DSA:3.40.190.290 91 295 8.1E-34 T 15-10-2018 C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 Pfam PF03466 LysR substrate binding domain 86 289 3.6E-33 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 Gene3D G3DSA:1.10.10.10 1 90 5.8E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.5E-17 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_08875 bc86c2ff51d92654624e9464f0d39cea 302 SUPERFAMILY SSF53850 87 290 2.99E-29 T 15-10-2018 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 Pfam PF01416 tRNA pseudouridine synthase 8 104 7.1E-12 T 15-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 Pfam PF01416 tRNA pseudouridine synthase 143 245 1.3E-32 T 15-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 PIRSF PIRSF001430 1 246 6.1E-88 T 15-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 SUPERFAMILY SSF55120 1 246 1.73E-88 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 Gene3D G3DSA:3.30.70.660 106 242 9.9E-52 T 15-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 239 3.4E-71 T 15-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 Gene3D G3DSA:3.30.70.580 1 105 2.9E-35 T 15-10-2018 C2I28_08845 5aba2da60a1c0db86a1e07822485b73a 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 37.488 T 15-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 15-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 Gene3D G3DSA:3.30.160.20 209 295 6.3E-95 T 15-10-2018 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 SMART SM00937 63 177 1.9E-63 T 15-10-2018 IPR005139 Peptide chain release factor GO:0006415 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 Pfam PF00472 RF-1 domain 210 319 3.5E-39 T 15-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 Gene3D G3DSA:1.20.58.410 1 101 6.8E-8 T 15-10-2018 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 SUPERFAMILY SSF75620 8 351 1.7E-131 T 15-10-2018 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 39.741 T 15-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 Gene3D G3DSA:3.30.70.1660 110 340 6.3E-95 T 15-10-2018 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 Pfam PF03462 PCRF domain 9 202 1.0E-73 T 15-10-2018 IPR005139 Peptide chain release factor GO:0006415 C2I28_07420 cec3e3b356fdc29f10dab759bd24e09c 355 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 352 5.4E-169 T 15-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 SUPERFAMILY SSF51735 84 207 3.09E-27 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 Gene3D G3DSA:3.40.50.720 83 211 1.3E-46 T 15-10-2018 C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 SUPERFAMILY SSF46785 9 80 2.23E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 Gene3D G3DSA:1.10.10.10 1 82 4.0E-31 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 6.4E-20 T 15-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 Pfam PF02629 CoA binding domain 84 179 8.2E-29 T 15-10-2018 IPR003781 CoA-binding GO:0048037 C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 210 38.997 T 15-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 C2I28_09315 2b449bc01478fcd09efbfa566d1493ec 212 SMART SM00881 81 181 8.9E-20 T 15-10-2018 IPR003781 CoA-binding GO:0048037 C2I28_16720 8c5c02aa283a9a49d8f6a9de000d1389 309 SUPERFAMILY SSF103481 43 146 5.1E-17 T 15-10-2018 C2I28_16720 8c5c02aa283a9a49d8f6a9de000d1389 309 Pfam PF00892 EamA-like transporter family 12 143 2.0E-27 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_16720 8c5c02aa283a9a49d8f6a9de000d1389 309 Pfam PF00892 EamA-like transporter family 156 291 1.2E-25 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_16720 8c5c02aa283a9a49d8f6a9de000d1389 309 SUPERFAMILY SSF103481 190 292 1.44E-15 T 15-10-2018 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.1E-15 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.1E-15 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.1E-15 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.1E-15 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 Pfam PF01165 Ribosomal protein S21 5 57 1.6E-21 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 5 56 5.4E-21 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 15-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.633 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 Gene3D G3DSA:1.20.5.1150 16 56 1.7E-18 T 15-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04355 970e50f556e85dc543b4c427c809b5dd 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 9.0E-9 T 15-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_21290 d3d78ab2f2033f08d52427476f56b1f2 407 SUPERFAMILY SSF103473 6 396 4.84E-89 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21290 d3d78ab2f2033f08d52427476f56b1f2 407 PIRSF PIRSF002808 3 406 5.9E-36 T 15-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I28_21290 d3d78ab2f2033f08d52427476f56b1f2 407 Pfam PF07690 Major Facilitator Superfamily 11 358 3.6E-61 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_21290 d3d78ab2f2033f08d52427476f56b1f2 407 Gene3D G3DSA:1.20.1250.20 3 194 5.7E-49 T 15-10-2018 C2I28_21290 d3d78ab2f2033f08d52427476f56b1f2 407 Gene3D G3DSA:1.20.1250.20 200 397 1.9E-39 T 15-10-2018 C2I28_06880 d0cae4d5a7d5a1ab114a7d137978ab2d 297 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 291 41.992 T 15-10-2018 IPR005337 RapZ-like family GO:0005524 C2I28_06880 d0cae4d5a7d5a1ab114a7d137978ab2d 297 SUPERFAMILY SSF52540 10 164 1.97E-10 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06880 d0cae4d5a7d5a1ab114a7d137978ab2d 297 PIRSF PIRSF005052 9 294 1.6E-108 T 15-10-2018 IPR005337 RapZ-like family GO:0005524 C2I28_06880 d0cae4d5a7d5a1ab114a7d137978ab2d 297 Pfam PF03668 P-loop ATPase protein family 9 292 1.2E-131 T 15-10-2018 IPR005337 RapZ-like family GO:0005524 C2I28_07385 c94c26a5119bfb8c2af467418ec531d6 153 Pfam PF02502 Ribose/Galactose Isomerase 3 140 4.9E-58 T 15-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_07385 c94c26a5119bfb8c2af467418ec531d6 153 Gene3D G3DSA:3.40.1400.10 1 148 3.2E-62 T 15-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_07385 c94c26a5119bfb8c2af467418ec531d6 153 SUPERFAMILY SSF89623 1 144 1.44E-59 T 15-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_07385 c94c26a5119bfb8c2af467418ec531d6 153 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.2E-63 T 15-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_07385 c94c26a5119bfb8c2af467418ec531d6 153 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 142 3.2E-53 T 15-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 C2I28_07385 c94c26a5119bfb8c2af467418ec531d6 153 PIRSF PIRSF005384 1 147 6.7E-60 T 15-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_10755 1775950de985f66403385e396a75d41a 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 11 148 5.4E-47 T 15-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 Gene3D G3DSA:3.90.110.10 150 316 2.6E-64 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 316 1.0E-36 T 15-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 9 317 47.356 T 15-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I28_10755 1775950de985f66403385e396a75d41a 318 SUPERFAMILY SSF51735 6 148 4.29E-55 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10755 1775950de985f66403385e396a75d41a 318 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 178 184 - T 15-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I28_10755 1775950de985f66403385e396a75d41a 318 Gene3D G3DSA:3.40.50.720 7 149 4.9E-59 T 15-10-2018 C2I28_10755 1775950de985f66403385e396a75d41a 318 PRINTS PR00086 L-lactate dehydrogenase signature 36 60 3.3E-47 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 PRINTS PR00086 L-lactate dehydrogenase signature 11 35 3.3E-47 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 PRINTS PR00086 L-lactate dehydrogenase signature 176 189 3.3E-47 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 PRINTS PR00086 L-lactate dehydrogenase signature 122 142 3.3E-47 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 PRINTS PR00086 L-lactate dehydrogenase signature 146 164 3.3E-47 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 SUPERFAMILY SSF56327 149 315 1.73E-59 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_10755 1775950de985f66403385e396a75d41a 318 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 14 311 5.5E-135 T 15-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 C2I28_10755 1775950de985f66403385e396a75d41a 318 PIRSF PIRSF000102 6 317 1.3E-117 T 15-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 PRINTS PR00149 Fumarate lyase superfamily signature 312 328 7.1E-35 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 PRINTS PR00149 Fumarate lyase superfamily signature 129 147 7.1E-35 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 PRINTS PR00149 Fumarate lyase superfamily signature 266 293 7.1E-35 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 PRINTS PR00149 Fumarate lyase superfamily signature 175 193 7.1E-35 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 455 5.8E-235 T 15-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 PRINTS PR00145 Argininosuccinate lyase family signature 312 328 6.7E-5 T 15-10-2018 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 PRINTS PR00145 Argininosuccinate lyase family signature 170 190 6.7E-5 T 15-10-2018 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 457 90.112 T 15-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 Pfam PF00206 Lyase 11 337 2.7E-115 T 15-10-2018 IPR022761 Fumarate lyase, N-terminal C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 SUPERFAMILY SSF48557 3 455 5.97E-153 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 Gene3D G3DSA:1.10.275.10 4 133 2.4E-52 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 Gene3D G3DSA:1.20.200.10 134 402 9.9E-115 T 15-10-2018 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 ProSitePatterns PS00163 Fumarate lyases signature. 312 321 - T 15-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 Gene3D G3DSA:1.10.40.30 403 457 1.0E-28 T 15-10-2018 C2I28_19655 98a9eb6bd8aef5dd2f2cac0602b25491 459 Pfam PF10415 Fumarase C C-terminus 403 456 6.5E-27 T 15-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_17770 6c998f7f977c7e0f10a994bab878d900 261 Pfam PF04445 Putative SAM-dependent methyltransferase 45 195 1.5E-13 T 15-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 C2I28_17770 6c998f7f977c7e0f10a994bab878d900 261 SUPERFAMILY SSF53335 4 258 2.65E-53 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_17770 6c998f7f977c7e0f10a994bab878d900 261 Gene3D G3DSA:3.40.50.150 70 256 2.9E-38 T 15-10-2018 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 SMART SM00363 5 70 3.0E-6 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 Pfam PF01479 S4 domain 5 47 1.9E-6 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 Gene3D G3DSA:3.10.290.10 1 63 2.8E-22 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 PIRSF PIRSF005578 1 268 8.9E-102 T 15-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 Pfam PF01728 FtsJ-like methyltransferase 61 243 2.5E-18 T 15-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 238 5.1E-93 T 15-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 SUPERFAMILY SSF53335 60 243 9.97E-18 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 Gene3D G3DSA:3.40.50.150 64 275 1.8E-82 T 15-10-2018 C2I28_03830 0d656e0e53dcf235e92b06435a9503ed 275 SUPERFAMILY SSF55174 4 70 1.28E-11 T 15-10-2018 C2I28_02665 c54dd86818e4e03fe6d89bcf0dbb3ff0 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 3.0E-16 T 15-10-2018 IPR009081 Phosphopantetheine binding ACP domain C2I28_02665 c54dd86818e4e03fe6d89bcf0dbb3ff0 77 SUPERFAMILY SSF47336 2 76 9.03E-24 T 15-10-2018 IPR036736 ACP-like superfamily C2I28_02665 c54dd86818e4e03fe6d89bcf0dbb3ff0 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 1.1E-34 T 15-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 C2I28_02665 c54dd86818e4e03fe6d89bcf0dbb3ff0 77 Gene3D G3DSA:1.10.1200.10 1 76 1.3E-29 T 15-10-2018 IPR036736 ACP-like superfamily C2I28_02665 c54dd86818e4e03fe6d89bcf0dbb3ff0 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.776 T 15-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Gene3D G3DSA:3.10.50.40 151 248 7.8E-96 T 15-10-2018 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 SUPERFAMILY SSF102735 1 130 3.14E-39 T 15-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Hamap MF_00303 Trigger factor [tig]. 1 427 24.216 T 15-10-2018 IPR005215 Trigger factor GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 1.8E-14 T 15-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 PIRSF PIRSF003095 1 428 9.9E-140 T 15-10-2018 IPR005215 Trigger factor GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 TIGRFAM TIGR00115 tig: trigger factor 12 421 3.2E-142 T 15-10-2018 IPR005215 Trigger factor GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Gene3D G3DSA:1.10.3120.10 115 425 7.8E-96 T 15-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 SUPERFAMILY SSF54534 89 243 3.34E-38 T 15-10-2018 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 7.5E-48 T 15-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 2.7E-45 T 15-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 SUPERFAMILY SSF109998 250 425 7.32E-45 T 15-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I28_05010 102e3e3f1e85f48da9b057d3ffdc2398 428 Gene3D G3DSA:3.30.70.1050 3 114 1.0E-32 T 15-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 C2I28_17065 52f93f0290051ec8b159f335b49ed147 512 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 429 1.5E-77 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_17065 52f93f0290051ec8b159f335b49ed147 512 Gene3D G3DSA:3.10.105.10 279 483 1.0E-29 T 15-10-2018 C2I28_17065 52f93f0290051ec8b159f335b49ed147 512 SUPERFAMILY SSF53850 35 506 6.64E-108 T 15-10-2018 C2I28_17065 52f93f0290051ec8b159f335b49ed147 512 Gene3D G3DSA:3.40.190.10 18 278 1.3E-66 T 15-10-2018 C2I28_17065 52f93f0290051ec8b159f335b49ed147 512 PIRSF PIRSF002741 1 510 5.3E-88 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_02855 393083051a3238a96f62c7d8d27420ae 435 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 337 357 - T 15-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I28_02855 393083051a3238a96f62c7d8d27420ae 435 Pfam PF00860 Permease family 20 389 6.0E-109 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_02855 393083051a3238a96f62c7d8d27420ae 435 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 15 414 6.7E-131 T 15-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I28_20960 6a9817f3f67cbba7a4bb8102401d7bc5 214 Pfam PF12804 MobA-like NTP transferase domain 8 175 3.4E-28 T 15-10-2018 IPR025877 MobA-like NTP transferase C2I28_20960 6a9817f3f67cbba7a4bb8102401d7bc5 214 Gene3D G3DSA:3.90.550.10 4 207 4.5E-39 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_20960 6a9817f3f67cbba7a4bb8102401d7bc5 214 SUPERFAMILY SSF53448 1 208 7.43E-19 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 SMART SM00845 326 473 6.4E-78 T 15-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 39.036 T 15-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 Gene3D G3DSA:1.10.150.380 298 411 4.4E-37 T 15-10-2018 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 2.5E-180 T 15-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 SUPERFAMILY SSF55931 4 294 1.63E-119 T 15-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 Gene3D G3DSA:1.10.10.410 413 476 5.3E-25 T 15-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 Pfam PF02637 GatB domain 326 473 3.4E-55 T 15-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 15-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 Pfam PF02934 GatB/GatE catalytic domain 6 286 3.7E-111 T 15-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 C2I28_09540 7b5260c4e5f0552d5005765162534b87 476 SUPERFAMILY SSF89095 295 400 4.45E-36 T 15-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 C2I28_05205 169908a50e95a170258d5895c1814d40 326 SMART SM00893 5 195 5.5E-44 T 15-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I28_05205 169908a50e95a170258d5895c1814d40 326 Gene3D G3DSA:3.40.50.620 2 194 8.0E-56 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05205 169908a50e95a170258d5895c1814d40 326 Pfam PF01012 Electron transfer flavoprotein domain 5 179 1.7E-44 T 15-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I28_05205 169908a50e95a170258d5895c1814d40 326 PIRSF PIRSF000089 1 323 1.9E-112 T 15-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 C2I28_05205 169908a50e95a170258d5895c1814d40 326 SUPERFAMILY SSF52402 4 191 2.16E-49 T 15-10-2018 C2I28_05205 169908a50e95a170258d5895c1814d40 326 Gene3D G3DSA:3.40.50.1220 195 326 2.1E-56 T 15-10-2018 C2I28_05205 169908a50e95a170258d5895c1814d40 326 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 1.5E-34 T 15-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 C2I28_05205 169908a50e95a170258d5895c1814d40 326 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 15-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 C2I28_05205 169908a50e95a170258d5895c1814d40 326 SUPERFAMILY SSF52467 198 317 7.27E-48 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 SMART SM00411 11 100 1.6E-51 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 PRINTS PR01727 Prokaryotic integration host factor signature 84 98 2.1E-22 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 PRINTS PR01727 Prokaryotic integration host factor signature 50 65 2.1E-22 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 PRINTS PR01727 Prokaryotic integration host factor signature 68 81 2.1E-22 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 SUPERFAMILY SSF47729 11 100 6.92E-36 T 15-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 Gene3D G3DSA:4.10.520.10 11 100 1.2E-41 T 15-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 56 75 - T 15-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 C2I28_03240 b4fd925715eb01394779f3896eeeb60b 100 Pfam PF00216 Bacterial DNA-binding protein 11 100 9.0E-39 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 Pfam PF00375 Sodium:dicarboxylate symporter family 8 400 2.0E-110 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 Gene3D G3DSA:1.10.3860.10 2 412 6.4E-123 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 294 317 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 7.9E-34 T 15-10-2018 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 7.9E-34 T 15-10-2018 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 7.9E-34 T 15-10-2018 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 PRINTS PR00173 Glutamate-aspartate symporter signature 144 166 7.9E-34 T 15-10-2018 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 7.9E-34 T 15-10-2018 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 7.9E-34 T 15-10-2018 C2I28_12345 c920b38082bc92a0a3231b0891b29a2a 422 SUPERFAMILY SSF118215 8 401 2.22E-119 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_17870 ba40ca63aa7c176b1b8bfc8de4b6c662 220 SUPERFAMILY SSF102588 2 218 1.05E-48 T 15-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I28_17870 ba40ca63aa7c176b1b8bfc8de4b6c662 220 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 3.4E-27 T 15-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 C2I28_17870 ba40ca63aa7c176b1b8bfc8de4b6c662 220 Gene3D G3DSA:3.40.50.10320 1 215 3.9E-47 T 15-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I28_17870 ba40ca63aa7c176b1b8bfc8de4b6c662 220 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 4 219 4.5E-97 T 15-10-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 C2I28_04215 fa953df6fbf495a7b0c60c5216293356 83 Pfam PF11116 Protein of unknown function (DUF2624) 1 82 7.2E-34 T 15-10-2018 IPR020277 Protein of unknown function DUF2624 C2I28_04215 fa953df6fbf495a7b0c60c5216293356 83 ProDom PD060869 YQFT IG BH1387 1 67 4.0E-15 T 15-10-2018 IPR020277 Protein of unknown function DUF2624 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 116 129 - T 15-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 Gene3D G3DSA:1.10.8.1210 382 430 5.0E-14 T 15-10-2018 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 197 428 2.3E-74 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 PIRSF PIRSF000185 7 430 6.1E-167 T 15-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 52 179 1.4E-54 T 15-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 230 250 6.6E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 356 367 6.6E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 188 210 6.6E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 108 122 6.6E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 SMART SM00839 199 428 2.5E-86 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 SUPERFAMILY SSF51735 197 429 3.95E-74 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_20195 f59b18625acf8577effd18574d3565cd 430 Gene3D G3DSA:3.40.50.10860 49 184 1.6E-176 T 15-10-2018 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 Gene3D G3DSA:3.40.50.720 204 357 1.6E-176 T 15-10-2018 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 Gene3D G3DSA:1.10.8.1210 25 358 1.6E-176 T 15-10-2018 C2I28_20195 f59b18625acf8577effd18574d3565cd 430 SUPERFAMILY SSF53223 21 199 6.72E-66 T 15-10-2018 C2I28_20370 ec5126bd95cbef185d914f65199ce128 187 SUPERFAMILY SSF103473 10 176 1.57E-25 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_20370 ec5126bd95cbef185d914f65199ce128 187 Gene3D G3DSA:1.20.1250.20 6 185 3.4E-25 T 15-10-2018 C2I28_20370 ec5126bd95cbef185d914f65199ce128 187 Pfam PF07690 Major Facilitator Superfamily 10 174 3.9E-21 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_00590 97abf2ffa461a9e4cc6e94738465cb9f 336 Gene3D G3DSA:3.40.50.2300 45 287 9.3E-78 T 15-10-2018 C2I28_00590 97abf2ffa461a9e4cc6e94738465cb9f 336 SUPERFAMILY SSF53822 34 255 1.95E-17 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_00590 97abf2ffa461a9e4cc6e94738465cb9f 336 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 33 324 5.6E-57 T 15-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 C2I28_00590 97abf2ffa461a9e4cc6e94738465cb9f 336 Gene3D G3DSA:3.40.50.2300 135 327 9.3E-78 T 15-10-2018 C2I28_07295 8c0482161c0c6a5788366d77c0f005e2 434 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 6.7E-178 T 15-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_07295 8c0482161c0c6a5788366d77c0f005e2 434 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 2.0E-118 T 15-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I28_07295 8c0482161c0c6a5788366d77c0f005e2 434 Gene3D G3DSA:3.65.10.10 7 414 4.8E-176 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_07295 8c0482161c0c6a5788366d77c0f005e2 434 Gene3D G3DSA:3.65.10.10 21 231 4.8E-176 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_07295 8c0482161c0c6a5788366d77c0f005e2 434 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.654 T 15-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_07295 8c0482161c0c6a5788366d77c0f005e2 434 SUPERFAMILY SSF55205 2 418 2.07E-144 T 15-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I28_11530 88d36611459c38401cc8cd72162987ab 270 Gene3D G3DSA:3.30.1240.10 87 193 6.3E-64 T 15-10-2018 C2I28_11530 88d36611459c38401cc8cd72162987ab 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 237 5.4E-26 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_11530 88d36611459c38401cc8cd72162987ab 270 Gene3D G3DSA:3.40.50.1000 8 264 6.3E-64 T 15-10-2018 IPR023214 HAD superfamily C2I28_11530 88d36611459c38401cc8cd72162987ab 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 7 18 - T 15-10-2018 C2I28_11530 88d36611459c38401cc8cd72162987ab 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 264 3.8E-60 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_11530 88d36611459c38401cc8cd72162987ab 270 SUPERFAMILY SSF56784 3 268 3.4E-68 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_11530 88d36611459c38401cc8cd72162987ab 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 264 8.9E-66 T 15-10-2018 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 SUPERFAMILY SSF52540 4 248 5.95E-48 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 Gene3D G3DSA:3.40.50.300 293 594 8.7E-60 T 15-10-2018 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 Pfam PF00005 ABC transporter 19 195 4.3E-27 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 ProSitePatterns PS00211 ABC transporters family signature. 449 463 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 Pfam PF00005 ABC transporter 348 477 5.3E-23 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 Gene3D G3DSA:3.40.50.300 2 289 2.3E-70 T 15-10-2018 C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 SMART SM00382 356 521 2.8E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 SMART SM00382 28 240 1.2E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 Pfam PF12848 ABC transporter 235 316 1.9E-25 T 15-10-2018 IPR032781 ABC-transporter extension domain C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 SUPERFAMILY SSF52540 314 533 4.33E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09310 00980aea13cd1c07b0385a142f05092f 644 Pfam PF16326 ABC transporter C-terminal domain 572 639 4.7E-13 T 15-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 C2I28_10345 f0ffd54b1a75b80c4d6e26a6647e826d 157 PIRSF PIRSF029256 2 157 6.0E-68 T 15-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 C2I28_10345 f0ffd54b1a75b80c4d6e26a6647e826d 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 1.3E-70 T 15-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 C2I28_10345 f0ffd54b1a75b80c4d6e26a6647e826d 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.217 T 15-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 C2I28_10345 f0ffd54b1a75b80c4d6e26a6647e826d 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 2.8E-35 T 15-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I28_10345 f0ffd54b1a75b80c4d6e26a6647e826d 157 Gene3D G3DSA:3.40.1280.10 1 157 1.8E-66 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_10345 f0ffd54b1a75b80c4d6e26a6647e826d 157 SUPERFAMILY SSF75217 3 155 1.64E-44 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 SUPERFAMILY SSF51569 1 285 9.38E-105 T 15-10-2018 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 PIRSF PIRSF001359 1 285 8.2E-128 T 15-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 9.5E-133 T 15-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 1.9E-117 T 15-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 Gene3D G3DSA:3.20.20.70 1 285 1.8E-114 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 15-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 8.6E-104 T 15-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I28_07450 85fa1774cd9ec8e12f7c603a7a0c8901 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 15-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 C2I28_20225 336cad29c84009019dc147a420494718 157 Pfam PF12867 DinB superfamily 11 147 2.1E-16 T 15-10-2018 IPR024775 DinB-like domain C2I28_20225 336cad29c84009019dc147a420494718 157 SUPERFAMILY SSF109854 4 144 2.75E-21 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_20225 336cad29c84009019dc147a420494718 157 Gene3D G3DSA:1.20.120.450 2 154 3.2E-14 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 Gene3D G3DSA:3.90.170.10 265 428 5.0E-70 T 15-10-2018 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 Pfam PF00709 Adenylosuccinate synthetase 4 420 3.0E-184 T 15-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 SUPERFAMILY SSF52540 1 426 5.52E-174 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 Gene3D G3DSA:3.40.440.10 5 252 6.4E-105 T 15-10-2018 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 15-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 SMART SM00788 3 422 7.0E-289 T 15-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 Gene3D G3DSA:1.10.300.10 100 199 6.4E-105 T 15-10-2018 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 426 5.1E-198 T 15-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 210.267 T 15-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I28_07900 bc071316cfe8b0bf41f2ca68f32b4ebb 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 15-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 C2I28_01505 c6f5f0f361d7f0d2d2d323f81692948e 368 SUPERFAMILY SSF82689 248 351 2.62E-19 T 15-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 C2I28_01505 c6f5f0f361d7f0d2d2d323f81692948e 368 SUPERFAMILY SSF82861 113 179 1.22E-9 T 15-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 C2I28_01505 c6f5f0f361d7f0d2d2d323f81692948e 368 Gene3D G3DSA:3.30.70.100 247 344 1.9E-17 T 15-10-2018 C2I28_01505 c6f5f0f361d7f0d2d2d323f81692948e 368 Pfam PF00924 Mechanosensitive ion channel 138 340 2.5E-62 T 15-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I28_01505 c6f5f0f361d7f0d2d2d323f81692948e 368 Gene3D G3DSA:2.30.30.60 196 245 1.5E-13 T 15-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I28_01505 c6f5f0f361d7f0d2d2d323f81692948e 368 SUPERFAMILY SSF50182 180 245 3.17E-18 T 15-10-2018 IPR010920 LSM domain superfamily C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 SUPERFAMILY SSF56024 283 435 2.47E-21 T 15-10-2018 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 Gene3D G3DSA:3.30.870.10 52 252 4.1E-34 T 15-10-2018 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 Pfam PF13091 PLD-like domain 299 425 6.5E-17 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 Pfam PF13091 PLD-like domain 70 220 6.3E-20 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 Gene3D G3DSA:3.30.870.10 253 471 1.6E-26 T 15-10-2018 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 SMART SM00155 154 181 0.001 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 SMART SM00155 374 401 0.0043 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_18335 b957763d3342013eccd32eb1d3e167ea 474 SUPERFAMILY SSF56024 48 227 2.98E-33 T 15-10-2018 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 SUPERFAMILY SSF52518 5 326 2.95E-116 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 Gene3D G3DSA:3.40.50.970 332 539 2.5E-82 T 15-10-2018 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 339 2.1E-153 T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 SUPERFAMILY SSF52518 342 528 7.94E-70 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 Gene3D G3DSA:3.40.50.970 4 331 3.1E-125 T 15-10-2018 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 Pfam PF02780 Transketolase, C-terminal domain 550 658 5.7E-12 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 SMART SM00861 355 526 5.6E-71 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 Pfam PF02779 Transketolase, pyrimidine binding domain 355 525 1.8E-46 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 15-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 SUPERFAMILY SSF52922 535 667 3.53E-42 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 667 1.1E-301 T 15-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 C2I28_01995 8a41a387184735c57cc25f671e57f2c4 668 Gene3D G3DSA:3.40.50.920 541 668 7.5E-44 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 Gene3D G3DSA:2.40.500.20 174 292 5.9E-42 T 15-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 SUPERFAMILY SSF54719 172 286 1.18E-39 T 15-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 SUPERFAMILY SSF46609 90 174 2.62E-30 T 15-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 Gene3D G3DSA:1.10.287.990 110 173 7.2E-24 T 15-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 180 282 2.8E-33 T 15-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 92 173 1.2E-25 T 15-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 PRINTS PR01703 Manganese superoxide dismutase signature 247 259 1.3E-19 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 PRINTS PR01703 Manganese superoxide dismutase signature 96 107 1.3E-19 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 PRINTS PR01703 Manganese superoxide dismutase signature 117 130 1.3E-19 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 PRINTS PR01703 Manganese superoxide dismutase signature 156 169 1.3E-19 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 PRINTS PR01703 Manganese superoxide dismutase signature 209 217 1.3E-19 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_21715 dcffaad375cc88212dcdef615d8c4c0d 294 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 249 256 - T 15-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 15-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 SUPERFAMILY SSF53223 1 121 1.53E-41 T 15-10-2018 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 Gene3D G3DSA:3.40.50.720 6 257 1.7E-116 T 15-10-2018 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 8.8E-43 T 15-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 237 253 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 254 272 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.1E-84 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 281 39.262 T 15-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 Gene3D G3DSA:3.40.50.10860 8 274 1.7E-116 T 15-10-2018 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 258 266 - T 15-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 SUPERFAMILY SSF51735 122 277 2.53E-51 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18320 e1bc1f3d13510d098d9de859df0dbe82 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 279 1.1E-68 T 15-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 C2I28_12560 498a3a9f0a714c525a94553773cf6969 333 Pfam PF11553 Protein of unknown function (DUF3231) 7 155 2.1E-36 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_12560 498a3a9f0a714c525a94553773cf6969 333 Pfam PF11553 Protein of unknown function (DUF3231) 172 329 5.4E-44 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_12560 498a3a9f0a714c525a94553773cf6969 333 Gene3D G3DSA:1.20.1260.10 1 147 5.1E-7 T 15-10-2018 IPR012347 Ferritin-like C2I28_14305 9b52dff952c34452ea43f658123c202c 221 SUPERFAMILY SSF56784 6 217 1.38E-52 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_14305 9b52dff952c34452ea43f658123c202c 221 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 6 217 6.9E-104 T 15-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 C2I28_14305 9b52dff952c34452ea43f658123c202c 221 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 6 186 2.8E-48 T 15-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 C2I28_14305 9b52dff952c34452ea43f658123c202c 221 Gene3D G3DSA:3.40.50.1000 6 209 1.8E-65 T 15-10-2018 IPR023214 HAD superfamily C2I28_14305 9b52dff952c34452ea43f658123c202c 221 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 2 216 48.739 T 15-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 C2I28_14305 9b52dff952c34452ea43f658123c202c 221 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 179 5.2E-30 T 15-10-2018 C2I28_14305 9b52dff952c34452ea43f658123c202c 221 Gene3D G3DSA:3.90.1470.20 15 134 1.8E-65 T 15-10-2018 C2I28_14305 9b52dff952c34452ea43f658123c202c 221 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 177 5.2E-20 T 15-10-2018 C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 Gene3D G3DSA:3.40.50.300 1 243 4.0E-77 T 15-10-2018 C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 SMART SM00382 30 218 7.7E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 SMART SM00930 263 338 2.9E-28 T 15-10-2018 IPR018449 NIL domain C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 Gene3D G3DSA:3.30.70.260 244 341 7.7E-29 T 15-10-2018 C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 Pfam PF09383 NIL domain 266 337 5.7E-20 T 15-10-2018 IPR018449 NIL domain C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 Pfam PF00005 ABC transporter 21 169 4.0E-37 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 SUPERFAMILY SSF55021 249 339 7.33E-24 T 15-10-2018 C2I28_06555 c43d5ded9f91805a62cf18bb0cfcf545 341 SUPERFAMILY SSF52540 1 240 2.47E-83 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23290 3d26794795b04bfa297c055641dfe03c 111 SUPERFAMILY SSF161219 10 95 1.57E-17 T 15-10-2018 IPR037274 Zinc finger, CHY-type superfamily GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 C2I28_23290 3d26794795b04bfa297c055641dfe03c 111 Pfam PF05495 CHY zinc finger 19 93 5.3E-12 T 15-10-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 C2I28_23290 3d26794795b04bfa297c055641dfe03c 111 PIRSF PIRSF017292 3 110 7.0E-42 T 15-10-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 7.5E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.5E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.5E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.6E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.6E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.6E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.6E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.6E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.6E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 SUPERFAMILY SSF51735 6 251 2.41E-83 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 3.7E-65 T 15-10-2018 C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 Gene3D G3DSA:3.40.50.720 1 261 3.1E-90 T 15-10-2018 C2I28_13385 3ea81789fb64998780a6c8c1a42bf860 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 67.397 T 15-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 Gene3D G3DSA:3.40.309.10 290 480 2.4E-188 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 Pfam PF00171 Aldehyde dehydrogenase family 49 510 2.3E-156 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 3.8E-259 T 15-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 SUPERFAMILY SSF53720 4 511 4.84E-156 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 Gene3D G3DSA:3.40.605.10 9 509 2.4E-188 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_11470 ebd862e44a049a9347b790a9c43aea45 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_02450 3d761ecd98d902d18791559343e5401d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.3E-24 T 15-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I28_02450 3d761ecd98d902d18791559343e5401d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.3E-24 T 15-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I28_02450 3d761ecd98d902d18791559343e5401d 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.3E-24 T 15-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I28_02450 3d761ecd98d902d18791559343e5401d 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 86 3.3E-35 T 15-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 C2I28_02450 3d761ecd98d902d18791559343e5401d 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.2E-31 T 15-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I28_02450 3d761ecd98d902d18791559343e5401d 89 PIRSF PIRSF004669 1 89 5.2E-35 T 15-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 C2I28_00290 353567a26c75296fba297b32db17147c 296 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 184 201 - T 15-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 C2I28_00290 353567a26c75296fba297b32db17147c 296 SUPERFAMILY SSF53697 4 247 1.4E-72 T 15-10-2018 C2I28_00290 353567a26c75296fba297b32db17147c 296 Pfam PF13580 SIS domain 35 164 2.1E-9 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_00290 353567a26c75296fba297b32db17147c 296 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 5 294 4.6E-125 T 15-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I28_00290 353567a26c75296fba297b32db17147c 296 Gene3D G3DSA:3.40.50.10490 1 217 2.2E-76 T 15-10-2018 C2I28_00290 353567a26c75296fba297b32db17147c 296 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 294 43.462 T 15-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I28_00290 353567a26c75296fba297b32db17147c 296 Gene3D G3DSA:1.10.8.1080 218 295 7.2E-30 T 15-10-2018 C2I28_00920 1b076b2cfeeda079bcdb776311179e91 118 Gene3D G3DSA:2.40.50.480 24 107 2.3E-11 T 15-10-2018 IPR036166 YxeA-like superfamily C2I28_00920 1b076b2cfeeda079bcdb776311179e91 118 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 106 2.6E-8 T 15-10-2018 IPR006542 Protein of unknown function DUF1093 C2I28_00920 1b076b2cfeeda079bcdb776311179e91 118 Pfam PF06486 Protein of unknown function (DUF1093) 29 98 6.3E-7 T 15-10-2018 IPR006542 Protein of unknown function DUF1093 C2I28_00920 1b076b2cfeeda079bcdb776311179e91 118 SUPERFAMILY SSF159121 28 105 7.85E-11 T 15-10-2018 IPR036166 YxeA-like superfamily C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 Gene3D G3DSA:3.40.640.10 20 261 1.6E-87 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 8 363 7.6E-155 T 15-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 Pfam PF00266 Aminotransferase class-V 8 352 4.3E-52 T 15-10-2018 IPR000192 Aminotransferase class V domain C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 364 48.731 T 15-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 SUPERFAMILY SSF53383 5 362 7.0E-113 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 Gene3D G3DSA:3.90.1150.10 262 364 1.4E-38 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_11090 894d4fe812121f13974fa6cfb731f898 365 PIRSF PIRSF000525 1 365 9.3E-150 T 15-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Gene3D G3DSA:3.40.50.12740 8 211 8.2E-36 T 15-10-2018 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF46894 142 207 1.43E-12 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF52172 6 113 4.7E-18 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00421 149 206 2.3E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00072 Response regulator receiver domain 10 120 2.0E-16 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 7.1E-10 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26230 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00448 8 122 1.9E-12 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Gene3D G3DSA:3.40.50.12740 8 211 8.2E-36 T 15-10-2018 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF46894 142 207 1.43E-12 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF52172 6 113 4.7E-18 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00421 149 206 2.3E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00072 Response regulator receiver domain 10 120 2.0E-16 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 7.1E-10 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_26330 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00448 8 122 1.9E-12 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Gene3D G3DSA:3.40.50.12740 8 211 8.2E-36 T 15-10-2018 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF46894 142 207 1.43E-12 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF52172 6 113 4.7E-18 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00421 149 206 2.3E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00072 Response regulator receiver domain 10 120 2.0E-16 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 7.1E-10 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27080 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00448 8 122 1.9E-12 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Gene3D G3DSA:3.40.50.12740 8 211 8.2E-36 T 15-10-2018 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF46894 142 207 1.43E-12 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 6.0E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SUPERFAMILY SSF52172 6 113 4.7E-18 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00421 149 206 2.3E-7 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00072 Response regulator receiver domain 10 120 2.0E-16 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 7.1E-10 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_27180 b5d440c3f4b8c5ddc3f04e0b667b3fd1 212 SMART SM00448 8 122 1.9E-12 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_22790 f04c397a04e991ff0a87d60983b02bdf 259 SUPERFAMILY SSF52091 140 241 3.34E-10 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_22790 f04c397a04e991ff0a87d60983b02bdf 259 SUPERFAMILY SSF55785 16 124 4.57E-6 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_22790 f04c397a04e991ff0a87d60983b02bdf 259 Gene3D G3DSA:3.30.450.20 14 123 6.2E-18 T 15-10-2018 C2I28_22790 f04c397a04e991ff0a87d60983b02bdf 259 Pfam PF01740 STAS domain 147 240 4.8E-5 T 15-10-2018 IPR002645 STAS domain C2I28_22790 f04c397a04e991ff0a87d60983b02bdf 259 Gene3D G3DSA:3.30.750.24 137 254 1.3E-27 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 SUPERFAMILY SSF52172 4 125 1.57E-32 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 SMART SM00448 3 113 4.0E-35 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 3.2E-19 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 Pfam PF00072 Response regulator receiver domain 7 112 1.1E-23 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 Gene3D G3DSA:1.10.10.10 129 223 7.9E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 SMART SM00862 149 220 2.2E-17 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 SUPERFAMILY SSF46894 125 220 6.24E-25 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_01130 2164096d7a110c8b6379cc0e13d9f622 223 Gene3D G3DSA:3.40.50.2300 4 128 5.2E-30 T 15-10-2018 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 Gene3D G3DSA:3.40.50.1860 5 253 1.3E-100 T 15-10-2018 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 211 4.3E-40 T 15-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 Hamap MF_00258 Glutamate racemase [murI]. 3 255 41.404 T 15-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 15-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 253 1.6E-90 T 15-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 SUPERFAMILY SSF53681 4 106 4.25E-37 T 15-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 15-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 Gene3D G3DSA:3.40.50.1860 94 206 1.3E-100 T 15-10-2018 C2I28_05080 ad91abb04088d3044115ef65f4cb61c6 264 SUPERFAMILY SSF53681 108 262 6.05E-42 T 15-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 C2I28_23725 748b45e259c84ee6c3ed7212e51e8829 180 SUPERFAMILY SSF55729 2 166 1.29E-36 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_23725 748b45e259c84ee6c3ed7212e51e8829 180 Pfam PF13302 Acetyltransferase (GNAT) domain 3 142 7.4E-18 T 15-10-2018 IPR000182 GNAT domain C2I28_23725 748b45e259c84ee6c3ed7212e51e8829 180 Gene3D G3DSA:3.40.630.30 1 177 1.3E-45 T 15-10-2018 C2I28_25515 5427757d6e90f2fe23e62f20f45458f5 137 Pfam PF17225 Domain of unknown function (DUF5300) 24 121 4.6E-16 T 15-10-2018 IPR033782 Domain of unknown function DUF5301 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 SUPERFAMILY SSF52172 2 126 9.25E-32 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 262 1.5E-131 T 15-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 152 255 2.2E-45 T 15-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 Pfam PF00072 Response regulator receiver domain 6 119 2.9E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 SUPERFAMILY SSF46894 146 260 3.06E-48 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 PIRSF PIRSF002937 1 262 1.3E-133 T 15-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 151 261 5.0E-58 T 15-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 SMART SM00448 4 119 4.7E-31 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 Gene3D G3DSA:3.40.50.2300 1 144 3.0E-32 T 15-10-2018 C2I28_03810 553dfd950fbedce17a44771090ed5da8 262 Gene3D G3DSA:1.10.10.10 145 262 8.9E-55 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 342 4.7E-160 T 15-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 Gene3D G3DSA:3.30.360.10 128 324 1.3E-143 T 15-10-2018 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 SUPERFAMILY SSF51735 5 157 5.57E-52 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 Gene3D G3DSA:3.40.50.720 7 338 1.3E-143 T 15-10-2018 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 PIRSF PIRSF000148 4 346 8.5E-133 T 15-10-2018 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 119 7.0E-35 T 15-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 SUPERFAMILY SSF55347 129 328 4.76E-75 T 15-10-2018 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 237 251 - T 15-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 327 2.4E-57 T 15-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 341 38.811 T 15-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_02260 d5715ba9008916e62e5f088eb82cdaaa 347 SMART SM00859 6 121 4.2E-46 T 15-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 C2I28_00270 58aa3459b1103425c4785d8e04aa98fa 392 Gene3D G3DSA:3.40.640.10 55 289 1.6E-135 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_00270 58aa3459b1103425c4785d8e04aa98fa 392 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 20 381 3.5E-140 T 15-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 C2I28_00270 58aa3459b1103425c4785d8e04aa98fa 392 SUPERFAMILY SSF53383 10 389 8.94E-103 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_00270 58aa3459b1103425c4785d8e04aa98fa 392 Gene3D G3DSA:3.90.1150.10 35 378 1.6E-135 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_00270 58aa3459b1103425c4785d8e04aa98fa 392 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 15-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 C2I28_00270 58aa3459b1103425c4785d8e04aa98fa 392 Pfam PF00155 Aminotransferase class I and II 40 381 4.8E-64 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 Pfam PF00702 haloacid dehalogenase-like hydrolase 385 599 1.7E-34 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 Gene3D G3DSA:3.40.1110.10 399 518 5.6E-77 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 Gene3D G3DSA:2.70.150.20 190 301 8.3E-33 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 Pfam PF00122 E1-E2 ATPase 201 368 9.2E-41 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 SUPERFAMILY SSF56784 386 686 1.15E-44 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 SUPERFAMILY SSF81653 200 295 2.35E-23 T 15-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 146 688 1.6E-163 T 15-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 522 7.0E-23 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 388 402 7.0E-23 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 246 260 7.0E-23 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 544 7.0E-23 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 605 7.0E-23 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 622 7.0E-23 T 15-10-2018 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 390 396 - T 15-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 168 670 3.8E-68 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 SUPERFAMILY SSF81665 151 667 1.96E-7 T 15-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I28_16980 f9719badedca3e23bfc13a2b7ad6da12 705 Gene3D G3DSA:3.40.50.1000 369 639 5.6E-77 T 15-10-2018 IPR023214 HAD superfamily C2I28_07655 32a7fe7643b3fb1da1ebc4c0b67a860d 289 Gene3D G3DSA:3.30.1240.10 82 209 7.7E-82 T 15-10-2018 C2I28_07655 32a7fe7643b3fb1da1ebc4c0b67a860d 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 253 6.6E-32 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_07655 32a7fe7643b3fb1da1ebc4c0b67a860d 289 Gene3D G3DSA:3.40.50.1000 3 277 7.7E-82 T 15-10-2018 IPR023214 HAD superfamily C2I28_07655 32a7fe7643b3fb1da1ebc4c0b67a860d 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 280 2.8E-65 T 15-10-2018 C2I28_07655 32a7fe7643b3fb1da1ebc4c0b67a860d 289 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 280 3.7E-56 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_07655 32a7fe7643b3fb1da1ebc4c0b67a860d 289 SUPERFAMILY SSF56784 1 282 8.9E-68 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 411 427 - T 15-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 SMART SM00463 709 787 8.4E-24 T 15-10-2018 IPR002625 Smr domain C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Gene3D G3DSA:3.40.50.300 294 649 3.0E-82 T 15-10-2018 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Gene3D G3DSA:3.30.1370.110 700 787 1.7E-23 T 15-10-2018 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 SMART SM00533 9 316 5.3E-28 T 15-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Gene3D G3DSA:1.10.1420.10 67 281 9.4E-7 T 15-10-2018 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 SUPERFAMILY SSF160443 710 786 2.88E-9 T 15-10-2018 IPR036063 Smr domain superfamily C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 SMART SM00534 329 514 7.2E-76 T 15-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Gene3D G3DSA:1.10.1420.10 135 260 9.4E-7 T 15-10-2018 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Pfam PF00488 MutS domain V 332 511 2.8E-33 T 15-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 786 22.395 T 15-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 Pfam PF01713 Smr domain 712 787 5.0E-20 T 15-10-2018 IPR002625 Smr domain C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 PIRSF PIRSF005814 1 787 4.4E-279 T 15-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 SUPERFAMILY SSF48334 25 289 1.18E-26 T 15-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 SUPERFAMILY SSF52540 294 515 3.42E-44 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05240 2d235b90a34ac2ffa4a8c9cfd57d8a65 787 TIGRFAM TIGR01069 mutS2: MutS2 family protein 4 786 3.3E-278 T 15-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 C2I28_12605 79bc484b2f197d54ea4c6a47d341d18a 223 PIRSF PIRSF003170 1 218 9.0E-34 T 15-10-2018 IPR026285 TenA_E protein C2I28_12605 79bc484b2f197d54ea4c6a47d341d18a 223 SUPERFAMILY SSF48613 1 214 5.19E-77 T 15-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I28_12605 79bc484b2f197d54ea4c6a47d341d18a 223 Pfam PF03070 TENA/THI-4/PQQC family 9 215 3.4E-65 T 15-10-2018 IPR004305 Thiaminase-2/PQQC C2I28_12605 79bc484b2f197d54ea4c6a47d341d18a 223 Gene3D G3DSA:1.20.910.10 1 223 2.8E-76 T 15-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I28_12605 79bc484b2f197d54ea4c6a47d341d18a 223 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 12 215 2.1E-73 T 15-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 Gene3D G3DSA:2.10.109.10 87 204 8.2E-42 T 15-10-2018 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 119 129 1.5E-10 T 15-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 159 171 1.5E-10 T 15-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 130 141 1.5E-10 T 15-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 Pfam PF01726 LexA DNA binding domain 2 64 1.6E-27 T 15-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 Pfam PF00717 Peptidase S24-like 122 186 2.1E-17 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 SUPERFAMILY SSF51306 81 202 2.96E-36 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 Gene3D G3DSA:1.10.10.10 1 67 2.1E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 Hamap MF_00015 LexA repressor [lexA]. 2 204 34.432 T 15-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 SUPERFAMILY SSF46785 1 69 5.19E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_02015 8d648cca5570ed2ddc71f8c67e04c179 205 TIGRFAM TIGR00498 lexA: repressor LexA 2 204 7.6E-82 T 15-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 C2I28_24065 43621cca1cd4554678cf8e0162490963 119 Pfam PF14534 Domain of unknown function (DUF4440) 23 108 6.0E-8 T 15-10-2018 IPR027843 Domain of unknown function DUF4440 C2I28_24065 43621cca1cd4554678cf8e0162490963 119 SUPERFAMILY SSF54427 7 115 2.82E-14 T 15-10-2018 IPR032710 NTF2-like domain superfamily C2I28_24065 43621cca1cd4554678cf8e0162490963 119 Gene3D G3DSA:3.10.450.50 3 115 1.1E-11 T 15-10-2018 C2I28_08835 87cd7eafee5be855550da2a751ad8472 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_08835 87cd7eafee5be855550da2a751ad8472 289 SMART SM00382 32 223 5.2E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08835 87cd7eafee5be855550da2a751ad8472 289 SUPERFAMILY SSF52540 7 237 8.32E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08835 87cd7eafee5be855550da2a751ad8472 289 Gene3D G3DSA:3.40.50.300 2 287 2.8E-78 T 15-10-2018 C2I28_08835 87cd7eafee5be855550da2a751ad8472 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 9.6E-124 T 15-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 C2I28_08835 87cd7eafee5be855550da2a751ad8472 289 Pfam PF00005 ABC transporter 23 174 2.0E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 Hamap MF_01393 ATP synthase subunit a [atpB]. 8 235 13.922 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 PRINTS PR00123 ATP synthase A subunit signature 162 184 2.3E-19 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 PRINTS PR00123 ATP synthase A subunit signature 215 230 2.3E-19 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 PRINTS PR00123 ATP synthase A subunit signature 78 94 2.3E-19 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 PRINTS PR00123 ATP synthase A subunit signature 146 161 2.3E-19 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 231 6.6E-50 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 Gene3D G3DSA:1.20.120.220 71 236 2.5E-41 T 15-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 15-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 Pfam PF00119 ATP synthase A chain 21 229 6.9E-58 T 15-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07345 c3a5ce356c207c6aea32594671355e08 236 SUPERFAMILY SSF81336 70 229 4.97E-41 T 15-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_17615 c2225c7e13ff60331aa5d4843f582255 351 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 15-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 C2I28_17615 c2225c7e13ff60331aa5d4843f582255 351 Gene3D G3DSA:3.40.718.10 1 351 1.5E-127 T 15-10-2018 C2I28_17615 c2225c7e13ff60331aa5d4843f582255 351 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 345 9.5E-84 T 15-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I28_17615 c2225c7e13ff60331aa5d4843f582255 351 SUPERFAMILY SSF53659 2 349 8.64E-115 T 15-10-2018 C2I28_17615 c2225c7e13ff60331aa5d4843f582255 351 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 348 8.4E-187 T 15-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 C2I28_17615 c2225c7e13ff60331aa5d4843f582255 351 SMART SM01329 5 345 1.2E-165 T 15-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Gene3D G3DSA:3.90.780.10 1023 1203 7.0E-40 T 15-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 SUPERFAMILY SSF55816 414 651 3.92E-44 T 15-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Gene3D G3DSA:3.60.21.10 700 1009 2.0E-80 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 SUPERFAMILY SSF56300 700 1005 7.4E-75 T 15-10-2018 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 ProSitePatterns PS00786 5'-nucleotidase signature 2. 784 795 - T 15-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Pfam PF00149 Calcineurin-like phosphoesterase 60 300 8.8E-15 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Pfam PF00149 Calcineurin-like phosphoesterase 707 939 3.5E-11 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 PRINTS PR01607 Apyrase family signature 57 75 1.3E-24 T 15-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 PRINTS PR01607 Apyrase family signature 283 306 1.3E-24 T 15-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 PRINTS PR01607 Apyrase family signature 257 274 1.3E-24 T 15-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 PRINTS PR01607 Apyrase family signature 587 606 1.3E-24 T 15-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 PRINTS PR01607 Apyrase family signature 335 355 1.3E-24 T 15-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 PRINTS PR01607 Apyrase family signature 486 509 1.3E-24 T 15-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Pfam PF02872 5'-nucleotidase, C-terminal domain 414 613 7.5E-23 T 15-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Pfam PF02872 5'-nucleotidase, C-terminal domain 1012 1151 1.1E-31 T 15-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Gene3D G3DSA:3.90.780.10 466 650 1.6E-61 T 15-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 Gene3D G3DSA:3.60.21.10 51 413 1.6E-121 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 ProSitePatterns PS00786 5'-nucleotidase signature 2. 145 156 - T 15-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 SUPERFAMILY SSF56300 54 412 2.4E-78 T 15-10-2018 C2I28_21595 5af095ab19fe9c4773d30fb5bfb6c99f 1212 SUPERFAMILY SSF55816 1010 1193 5.36E-38 T 15-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 C2I28_14125 eaebc9a66a73657a01038b17ba8f1563 245 SMART SM00382 30 213 3.5E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14125 eaebc9a66a73657a01038b17ba8f1563 245 Pfam PF00005 ABC transporter 22 165 1.7E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14125 eaebc9a66a73657a01038b17ba8f1563 245 SUPERFAMILY SSF52540 1 229 1.12E-63 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14125 eaebc9a66a73657a01038b17ba8f1563 245 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_14125 eaebc9a66a73657a01038b17ba8f1563 245 Gene3D G3DSA:3.40.50.300 1 243 2.7E-69 T 15-10-2018 C2I28_01990 356a3a03185dcf479972239a2e25d06a 146 Gene3D G3DSA:3.30.310.250 1 146 2.5E-46 T 15-10-2018 IPR038449 SirA superfamily C2I28_01990 356a3a03185dcf479972239a2e25d06a 146 Pfam PF10747 Sporulation inhibitor of replication protein SirA 2 141 1.9E-34 T 15-10-2018 IPR019683 Sporulation inhibitor of replication protein SirA C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 PRINTS PR01415 Ankyrin repeat signature 37 52 3.9E-8 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 PRINTS PR01415 Ankyrin repeat signature 87 101 3.9E-8 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 SUPERFAMILY SSF48403 8 159 4.09E-41 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 Gene3D G3DSA:1.25.40.20 6 106 7.7E-28 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 Pfam PF12796 Ankyrin repeats (3 copies) 10 66 8.9E-10 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 Pfam PF12796 Ankyrin repeats (3 copies) 76 159 6.6E-14 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 Gene3D G3DSA:1.25.40.960 107 164 7.0E-16 T 15-10-2018 C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 SMART SM00248 104 133 9.9E-5 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 SMART SM00248 71 100 0.0016 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 SMART SM00248 137 165 330.0 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_00495 6f55709e594a1c144c8a1e921cfe092f 165 SMART SM00248 36 65 9.1E-7 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_12430 d55ee58ef41f48aa3750702fe8e28178 210 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 8 203 1.2E-34 T 15-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 C2I28_12430 d55ee58ef41f48aa3750702fe8e28178 210 SUPERFAMILY SSF56529 6 200 7.46E-46 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_12430 d55ee58ef41f48aa3750702fe8e28178 210 Gene3D G3DSA:3.90.850.10 1 207 1.8E-51 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 SUPERFAMILY SSF47781 500 587 1.65E-22 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 567 3.1E-211 T 15-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Pfam PF01541 GIY-YIG catalytic domain 16 90 3.3E-9 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 SUPERFAMILY SSF82771 14 97 8.63E-23 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Pfam PF02151 UvrB/uvrC motif 200 230 2.6E-10 T 15-10-2018 IPR001943 UVR domain GO:0005515 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Gene3D G3DSA:3.30.420.340 363 521 2.5E-61 T 15-10-2018 IPR038476 UvrC homology region 2 superfamily C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Gene3D G3DSA:1.10.150.20 525 587 3.9E-23 T 15-10-2018 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 371 521 3.0E-54 T 15-10-2018 IPR001162 UvrC family homology region C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 585 28.532 T 15-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 SUPERFAMILY SSF46600 183 235 1.44E-13 T 15-10-2018 IPR036876 UVR domain superfamily C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Pfam PF12826 Helix-hairpin-helix motif 540 587 1.0E-6 T 15-10-2018 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 Gene3D G3DSA:3.40.1440.10 1 99 1.8E-36 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_05190 03cd446a82f39e2f3a64daace91e3a24 588 SMART SM00465 15 95 5.4E-21 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 Pfam PF07690 Major Facilitator Superfamily 29 368 9.0E-48 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 PRINTS PR01035 Tetracycline resistance protein signature 114 135 4.6E-10 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 PRINTS PR01035 Tetracycline resistance protein signature 174 194 4.6E-10 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 PRINTS PR01035 Tetracycline resistance protein signature 30 46 4.6E-10 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 PRINTS PR01035 Tetracycline resistance protein signature 87 111 4.6E-10 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 PRINTS PR01035 Tetracycline resistance protein signature 287 308 4.6E-10 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 397 1.1E-98 T 15-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 Gene3D G3DSA:1.20.1720.10 20 399 3.0E-101 T 15-10-2018 C2I28_09610 fde0ae13687e8eca2436334a96ff47d3 406 SUPERFAMILY SSF103473 11 404 2.35E-64 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_19115 a3dd0e43c1b2f6711ee2de4ed5ee6df2 146 TIGRFAM TIGR03646 YtoQ_fam: YtoQ family protein 3 146 2.3E-70 T 15-10-2018 IPR019884 YtoQ family protein C2I28_19115 a3dd0e43c1b2f6711ee2de4ed5ee6df2 146 Pfam PF11071 Nucleoside 2-deoxyribosyltransferase YtoQ 6 145 1.3E-66 T 15-10-2018 IPR019884 YtoQ family protein C2I28_15115 3f5d18206c7db407421e5a6d47982361 393 Gene3D G3DSA:3.90.1150.10 253 391 3.7E-46 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_15115 3f5d18206c7db407421e5a6d47982361 393 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 383 4.3E-149 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_15115 3f5d18206c7db407421e5a6d47982361 393 Gene3D G3DSA:3.40.640.10 1 252 2.8E-94 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_15115 3f5d18206c7db407421e5a6d47982361 393 SUPERFAMILY SSF53383 10 384 7.98E-113 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_15115 3f5d18206c7db407421e5a6d47982361 393 PIRSF PIRSF001434 1 387 9.0E-147 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_24935 0318e15b2ec6a5f00496849949730b28 467 Pfam PF07690 Major Facilitator Superfamily 31 366 1.1E-35 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_24935 0318e15b2ec6a5f00496849949730b28 467 Gene3D G3DSA:1.20.1250.20 17 439 1.5E-67 T 15-10-2018 C2I28_24935 0318e15b2ec6a5f00496849949730b28 467 SUPERFAMILY SSF103473 15 435 1.44E-70 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_24935 0318e15b2ec6a5f00496849949730b28 467 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_16500 711905055eb96701002b60b698981b02 140 Gene3D G3DSA:3.30.70.920 53 134 1.1E-18 T 15-10-2018 C2I28_16500 711905055eb96701002b60b698981b02 140 SUPERFAMILY SSF54909 63 133 5.77E-15 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_16500 711905055eb96701002b60b698981b02 140 Pfam PF01037 Lrp/AsnC ligand binding domain 74 118 2.5E-12 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_16500 711905055eb96701002b60b698981b02 140 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.4E-16 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_16500 711905055eb96701002b60b698981b02 140 Gene3D G3DSA:1.10.10.10 1 52 1.2E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16500 711905055eb96701002b60b698981b02 140 SMART SM00344 1 105 3.6E-34 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_16500 711905055eb96701002b60b698981b02 140 SUPERFAMILY SSF46785 1 58 4.32E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16500 711905055eb96701002b60b698981b02 140 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 7.1E-15 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_16500 711905055eb96701002b60b698981b02 140 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 7.1E-15 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_16500 711905055eb96701002b60b698981b02 140 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 7.1E-15 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_14950 86f43c0701f10464937cbe4b7c8449d5 225 Pfam PF04298 Putative neutral zinc metallopeptidase 4 218 4.7E-93 T 15-10-2018 IPR007395 Putative neutral zinc metallopeptidase C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 SMART SM00895 99 226 4.4E-22 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 Gene3D G3DSA:1.10.10.10 1 74 1.3E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.2E-19 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 SMART SM00345 15 74 5.2E-19 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.2E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.2E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 SUPERFAMILY SSF48008 95 234 1.91E-30 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 Gene3D G3DSA:1.20.120.530 80 233 6.4E-31 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 Pfam PF07729 FCD domain 100 225 1.0E-25 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_14235 183fc9bf29b9e3948f9487e2cf4a3c64 239 SUPERFAMILY SSF46785 5 78 1.08E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 Gene3D G3DSA:3.60.15.10 11 444 3.7E-182 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 555 5.3E-200 T 15-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 15-10-2018 IPR001587 Ribonuclease J, conserved site C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 Pfam PF00753 Metallo-beta-lactamase superfamily 21 166 3.0E-14 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 SUPERFAMILY SSF56281 9 426 7.23E-98 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 PIRSF PIRSF004803 2 557 6.2E-237 T 15-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 SMART SM00849 20 214 3.6E-26 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 Gene3D G3DSA:3.40.50.10710 207 357 3.7E-182 T 15-10-2018 C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 Gene3D G3DSA:3.10.20.580 451 557 1.6E-37 T 15-10-2018 C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 406 1.5E-8 T 15-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I28_15845 a15a5bfc0a40caaaa46257020cd5b1bf 557 Hamap MF_01491 Ribonuclease J [rnj]. 3 557 46.223 T 15-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I28_01365 85f1bf243d0d9cbfdc289df80d384e4f 213 Gene3D G3DSA:3.40.50.720 1 211 5.8E-53 T 15-10-2018 C2I28_01365 85f1bf243d0d9cbfdc289df80d384e4f 213 SUPERFAMILY SSF51735 1 211 6.63E-32 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_01365 85f1bf243d0d9cbfdc289df80d384e4f 213 Pfam PF13460 NAD(P)H-binding 7 194 5.6E-23 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 Pfam PF00849 RNA pseudouridylate synthase 88 242 3.3E-36 T 15-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 10 298 1.1E-105 T 15-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 SUPERFAMILY SSF55120 73 300 1.94E-77 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 SMART SM00363 15 72 9.5E-10 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 Pfam PF01479 S4 domain 15 61 6.8E-11 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 SUPERFAMILY SSF55174 15 101 4.71E-15 T 15-10-2018 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 Gene3D G3DSA:3.10.290.10 3 70 1.3E-19 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 15-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_02865 598b7c05f5b9f766ca7f44231ee656fc 304 Gene3D G3DSA:3.30.2350.10 81 303 5.1E-76 T 15-10-2018 C2I28_01240 da86c7ab464f6fc92f52692200dd0c8b 706 Pfam PF06202 Amylo-alpha-1,6-glucosidase 269 626 8.3E-18 T 15-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 C2I28_01240 da86c7ab464f6fc92f52692200dd0c8b 706 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 6 199 3.9E-51 T 15-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal C2I28_01240 da86c7ab464f6fc92f52692200dd0c8b 706 SUPERFAMILY SSF48208 215 682 4.18E-87 T 15-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 C2I28_01240 da86c7ab464f6fc92f52692200dd0c8b 706 Gene3D G3DSA:1.50.10.10 264 636 2.7E-57 T 15-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 C2I28_16795 9a7a7b8e71a955f4ab3557e93821d19d 116 SMART SM01022 20 115 1.9E-4 T 15-10-2018 IPR007374 ASCH domain C2I28_16795 9a7a7b8e71a955f4ab3557e93821d19d 116 SUPERFAMILY SSF88697 20 114 2.98E-12 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_16795 9a7a7b8e71a955f4ab3557e93821d19d 116 Pfam PF04266 ASCH domain 28 114 2.3E-4 T 15-10-2018 IPR007374 ASCH domain C2I28_13300 83586d5bf0b35c00be944b85401f5c30 236 Pfam PF13398 Peptidase M50B-like 36 230 6.6E-38 T 15-10-2018 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 SMART SM00342 440 523 9.2E-24 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 Gene3D G3DSA:1.10.10.60 421 477 8.3E-14 T 15-10-2018 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 Pfam PF00072 Response regulator receiver domain 3 112 9.1E-26 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 477 519 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 Pfam PF12833 Helix-turn-helix domain 447 523 1.4E-17 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 SUPERFAMILY SSF52172 1 155 3.13E-32 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 507 523 6.1E-6 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 492 507 6.1E-6 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 Gene3D G3DSA:3.40.50.2300 1 137 2.6E-33 T 15-10-2018 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 SMART SM00448 1 115 6.8E-31 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 SUPERFAMILY SSF46689 476 524 3.76E-12 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 Gene3D G3DSA:1.10.10.2730 478 524 3.0E-21 T 15-10-2018 C2I28_11190 6e2e708e3be3678e85def3b1bedf3594 527 SUPERFAMILY SSF46689 425 473 3.49E-5 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 713 799 2.0E-10 T 15-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 SUPERFAMILY SSF101790 730 802 7.36E-12 T 15-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Gene3D G3DSA:3.30.1360.120 421 694 2.8E-78 T 15-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Pfam PF01266 FAD dependent oxidoreductase 6 368 1.1E-48 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Gene3D G3DSA:3.30.70.1400 499 719 2.8E-78 T 15-10-2018 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 SUPERFAMILY SSF51905 4 416 1.99E-58 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Gene3D G3DSA:3.30.9.10 86 331 5.7E-136 T 15-10-2018 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 SUPERFAMILY SSF103025 421 722 7.69E-62 T 15-10-2018 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Pfam PF01571 Aminomethyltransferase folate-binding domain 429 703 4.4E-51 T 15-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Gene3D G3DSA:2.40.30.110 726 801 1.2E-21 T 15-10-2018 C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Gene3D G3DSA:3.50.50.60 7 387 5.7E-136 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_15695 730b780fb73242096163c3f31cd1b173 808 Pfam PF16350 FAD dependent oxidoreductase central domain 371 426 1.2E-15 T 15-10-2018 IPR032503 FAD dependent oxidoreductase, central domain C2I28_15695 730b780fb73242096163c3f31cd1b173 808 SUPERFAMILY SSF54373 220 331 7.45E-26 T 15-10-2018 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 SUPERFAMILY SSF55811 23 107 1.9E-18 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 PRINTS PR00502 NUDIX hydrolase family signature 62 77 1.6E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 PRINTS PR00502 NUDIX hydrolase family signature 48 62 1.6E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 15-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 Gene3D G3DSA:3.90.79.10 1 155 9.6E-45 T 15-10-2018 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 154 3.5E-64 T 15-10-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 C2I28_05890 a8a7e22cdbdf29c84124aa1c37aba82d 156 Pfam PF00293 NUDIX domain 26 87 6.7E-12 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_26795 feaa08fa76c4707bad5ba68d8521a0a1 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-9 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_26795 feaa08fa76c4707bad5ba68d8521a0a1 94 Gene3D G3DSA:2.10.260.10 1 54 7.8E-17 T 15-10-2018 C2I28_26795 feaa08fa76c4707bad5ba68d8521a0a1 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 50 2.2E-8 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_26795 feaa08fa76c4707bad5ba68d8521a0a1 94 SUPERFAMILY SSF89447 2 50 5.89E-13 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_26795 feaa08fa76c4707bad5ba68d8521a0a1 94 SMART SM00966 8 51 3.9E-7 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_10700 b9364d3b7b6d7719c72bcde9657abe4e 175 Gene3D G3DSA:3.40.630.30 5 170 2.2E-30 T 15-10-2018 C2I28_10700 b9364d3b7b6d7719c72bcde9657abe4e 175 SUPERFAMILY SSF55729 6 152 7.25E-24 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_10700 b9364d3b7b6d7719c72bcde9657abe4e 175 Pfam PF00583 Acetyltransferase (GNAT) family 43 150 2.5E-16 T 15-10-2018 IPR000182 GNAT domain C2I28_03685 a1e1679907791fd785047da7218f7801 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 132 433 2.0E-37 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_03685 a1e1679907791fd785047da7218f7801 453 Gene3D G3DSA:3.50.50.60 233 376 7.2E-47 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03685 a1e1679907791fd785047da7218f7801 453 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 12 120 7.3E-40 T 15-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 C2I28_03685 a1e1679907791fd785047da7218f7801 453 Gene3D G3DSA:1.10.1060.10 2 127 2.3E-42 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_03685 a1e1679907791fd785047da7218f7801 453 Gene3D G3DSA:3.50.50.60 128 232 3.3E-14 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03685 a1e1679907791fd785047da7218f7801 453 SUPERFAMILY SSF46548 9 142 1.78E-32 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_03685 a1e1679907791fd785047da7218f7801 453 SUPERFAMILY SSF51971 130 377 1.35E-64 T 15-10-2018 C2I28_03685 a1e1679907791fd785047da7218f7801 453 PRINTS PR00419 Adrenodoxin reductase family signature 198 208 1.4E-19 T 15-10-2018 C2I28_03685 a1e1679907791fd785047da7218f7801 453 PRINTS PR00419 Adrenodoxin reductase family signature 133 155 1.4E-19 T 15-10-2018 C2I28_03685 a1e1679907791fd785047da7218f7801 453 PRINTS PR00419 Adrenodoxin reductase family signature 156 169 1.4E-19 T 15-10-2018 C2I28_03685 a1e1679907791fd785047da7218f7801 453 PRINTS PR00419 Adrenodoxin reductase family signature 266 280 1.4E-19 T 15-10-2018 C2I28_19490 2d0af59a9583522a6281dd587cb86232 212 SUPERFAMILY SSF52242 75 167 8.11E-15 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_19490 2d0af59a9583522a6281dd587cb86232 212 Gene3D G3DSA:3.40.50.280 73 199 2.4E-21 T 15-10-2018 C2I28_19490 2d0af59a9583522a6281dd587cb86232 212 Pfam PF02607 B12 binding domain 2 61 4.8E-8 T 15-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_19490 2d0af59a9583522a6281dd587cb86232 212 Gene3D G3DSA:1.10.1240.10 1 67 4.7E-10 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_19490 2d0af59a9583522a6281dd587cb86232 212 Pfam PF02310 B12 binding domain 77 162 9.5E-14 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_06395 60b4c304f990d55107d393ea7373b3bc 121 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 6 110 1.0E-37 T 15-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 C2I28_06395 60b4c304f990d55107d393ea7373b3bc 121 SUPERFAMILY SSF89360 4 97 1.55E-30 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_06395 60b4c304f990d55107d393ea7373b3bc 121 Gene3D G3DSA:2.60.300.12 5 113 3.7E-36 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_06395 60b4c304f990d55107d393ea7373b3bc 121 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 92 109 - T 15-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 C2I28_06395 60b4c304f990d55107d393ea7373b3bc 121 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 106 5.1E-22 T 15-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Pfam PF01476 LysM domain 4 45 5.8E-12 T 15-10-2018 IPR018392 LysM domain C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Pfam PF01476 LysM domain 50 93 1.5E-9 T 15-10-2018 IPR018392 LysM domain C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Pfam PF00704 Glycosyl hydrolases family 18 143 400 6.3E-30 T 15-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 SUPERFAMILY SSF54106 48 93 1.07E-9 T 15-10-2018 C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Gene3D G3DSA:3.10.50.10 318 374 9.0E-107 T 15-10-2018 IPR029070 Chitinase insertion domain superfamily C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 SUPERFAMILY SSF54106 2 45 4.32E-11 T 15-10-2018 C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 SUPERFAMILY SSF51445 127 415 1.93E-46 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Gene3D G3DSA:3.10.350.10 2 48 5.6E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Gene3D G3DSA:3.20.20.80 129 400 9.0E-107 T 15-10-2018 C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 Gene3D G3DSA:3.10.350.10 49 93 7.0E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 SMART SM00636 93 403 2.3E-30 T 15-10-2018 IPR011583 Chitinase II GO:0008061 C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 SMART SM00257 49 93 8.9E-13 T 15-10-2018 IPR018392 LysM domain C2I28_16615 61e1fe47922ad7a3d17bddc2337911ce 420 SMART SM00257 3 46 1.0E-12 T 15-10-2018 IPR018392 LysM domain C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 Pfam PF02142 MGS-like domain 15 130 2.7E-29 T 15-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 SUPERFAMILY SSF53927 208 512 2.61E-126 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 SUPERFAMILY SSF52335 3 194 1.83E-71 T 15-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 512 5.4E-236 T 15-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 446 1.8E-119 T 15-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 Gene3D G3DSA:3.40.140.20 386 512 1.7E-56 T 15-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 SMART SM00798 135 447 1.9E-198 T 15-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 512 44.907 T 15-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 SMART SM00851 15 130 6.3E-57 T 15-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 Gene3D G3DSA:3.40.140.20 204 361 1.4E-60 T 15-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 PIRSF PIRSF000414 1 512 9.5E-213 T 15-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09475 29d05f1fa7fcba3687b5110b53f469d8 512 Gene3D G3DSA:3.40.50.1380 1 197 7.6E-89 T 15-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I28_13700 f551034a31338fecdb62460571bdacfc 326 Gene3D G3DSA:3.10.580.10 199 324 1.1E-37 T 15-10-2018 C2I28_13700 f551034a31338fecdb62460571bdacfc 326 Pfam PF00571 CBS domain 274 323 5.0E-6 T 15-10-2018 IPR000644 CBS domain C2I28_13700 f551034a31338fecdb62460571bdacfc 326 Pfam PF00571 CBS domain 204 261 3.9E-7 T 15-10-2018 IPR000644 CBS domain C2I28_13700 f551034a31338fecdb62460571bdacfc 326 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 48 316 1.9E-98 T 15-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 C2I28_13700 f551034a31338fecdb62460571bdacfc 326 SMART SM00116 278 326 0.0033 T 15-10-2018 IPR000644 CBS domain C2I28_13700 f551034a31338fecdb62460571bdacfc 326 SMART SM00116 213 261 0.0019 T 15-10-2018 IPR000644 CBS domain C2I28_13700 f551034a31338fecdb62460571bdacfc 326 Gene3D G3DSA:3.40.50.10490 6 198 1.8E-61 T 15-10-2018 C2I28_13700 f551034a31338fecdb62460571bdacfc 326 SUPERFAMILY SSF53697 11 322 1.6E-65 T 15-10-2018 C2I28_13700 f551034a31338fecdb62460571bdacfc 326 PIRSF PIRSF004692 1 326 2.7E-123 T 15-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 C2I28_13700 f551034a31338fecdb62460571bdacfc 326 Pfam PF01380 SIS domain 44 174 2.4E-29 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 7.8E-21 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 Pfam PF01197 Ribosomal protein L31 1 79 1.4E-28 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 Gene3D G3DSA:2.30.170.50 1 81 2.0E-26 T 15-10-2018 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.8 T 15-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 SUPERFAMILY SSF143800 1 79 6.67E-24 T 15-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.7E-19 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.7E-19 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05935 30f0977dfe9c9af2756a074af17340ba 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.7E-19 T 15-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02200 d4f2080fa64facc9b98569e25b0890bb 431 SUPERFAMILY SSF63411 12 231 7.33E-21 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_02200 d4f2080fa64facc9b98569e25b0890bb 431 Gene3D G3DSA:3.30.830.10 6 235 8.1E-58 T 15-10-2018 C2I28_02200 d4f2080fa64facc9b98569e25b0890bb 431 Pfam PF05193 Peptidase M16 inactive domain 185 358 7.5E-24 T 15-10-2018 IPR007863 Peptidase M16, C-terminal C2I28_02200 d4f2080fa64facc9b98569e25b0890bb 431 Gene3D G3DSA:3.30.830.10 241 426 2.2E-44 T 15-10-2018 C2I28_02200 d4f2080fa64facc9b98569e25b0890bb 431 SUPERFAMILY SSF63411 248 415 5.17E-32 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_08715 333f74970d252288b5a7197528688f48 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.7 T 15-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 C2I28_08715 333f74970d252288b5a7197528688f48 218 Gene3D G3DSA:3.30.300.20 17 106 2.4E-32 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_08715 333f74970d252288b5a7197528688f48 218 SMART SM00322 59 124 3.5E-8 T 15-10-2018 IPR004087 K Homology domain GO:0003676 C2I28_08715 333f74970d252288b5a7197528688f48 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.9E-39 T 15-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08715 333f74970d252288b5a7197528688f48 218 Pfam PF07650 KH domain 37 109 2.6E-20 T 15-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08715 333f74970d252288b5a7197528688f48 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 4.9E-97 T 15-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 C2I28_08715 333f74970d252288b5a7197528688f48 218 Gene3D G3DSA:3.30.1140.32 107 207 1.0E-40 T 15-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08715 333f74970d252288b5a7197528688f48 218 SUPERFAMILY SSF54821 107 205 5.62E-38 T 15-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08715 333f74970d252288b5a7197528688f48 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 15-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08715 333f74970d252288b5a7197528688f48 218 SUPERFAMILY SSF54814 2 105 1.86E-38 T 15-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I28_01670 a511f11473273be64ec850f860d1926b 208 SUPERFAMILY SSF52218 1 207 3.49E-51 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_01670 a511f11473273be64ec850f860d1926b 208 Gene3D G3DSA:3.40.50.360 1 208 6.1E-63 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_01670 a511f11473273be64ec850f860d1926b 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 30.555 T 15-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I28_01670 a511f11473273be64ec850f860d1926b 208 Pfam PF02525 Flavodoxin-like fold 3 203 2.6E-45 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 Pfam PF00005 ABC transporter 272 427 2.3E-23 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 SMART SM00382 29 220 2.1E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 SMART SM00382 281 476 8.5E-6 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 Gene3D G3DSA:3.40.50.300 3 248 1.2E-55 T 15-10-2018 C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 Gene3D G3DSA:3.40.50.300 265 497 3.4E-48 T 15-10-2018 C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 SUPERFAMILY SSF52540 5 228 4.02E-56 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 SUPERFAMILY SSF52540 272 488 1.36E-45 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14325 9b861dd79958c31a7675c1230ad2b6ee 501 Pfam PF00005 ABC transporter 20 173 3.7E-27 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 SUPERFAMILY SSF55031 178 283 2.62E-29 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_14695 636ee482fa8fbc7700596babf510908e 375 Pfam PF01546 Peptidase family M20/M25/M40 67 362 9.8E-25 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 Gene3D G3DSA:3.30.70.360 173 287 2.4E-121 T 15-10-2018 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 Gene3D G3DSA:3.40.630.10 7 357 2.4E-121 T 15-10-2018 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 361 7.8E-89 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 PIRSF PIRSF005962 1 375 2.2E-111 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 Pfam PF07687 Peptidase dimerisation domain 180 271 1.1E-10 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_14695 636ee482fa8fbc7700596babf510908e 375 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 63.198 T 15-10-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 C2I28_14695 636ee482fa8fbc7700596babf510908e 375 SUPERFAMILY SSF53187 3 367 4.07E-68 T 15-10-2018 C2I28_12880 4ec8210b23315a3bd90024202ebd2365 122 SMART SM00448 2 115 1.6E-37 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12880 4ec8210b23315a3bd90024202ebd2365 122 Gene3D G3DSA:3.40.50.12740 1 122 9.5E-40 T 15-10-2018 C2I28_12880 4ec8210b23315a3bd90024202ebd2365 122 Pfam PF00072 Response regulator receiver domain 4 115 5.6E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12880 4ec8210b23315a3bd90024202ebd2365 122 SUPERFAMILY SSF52172 1 120 7.68E-38 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_16315 d0c8c24af5271cc674befe610586ba01 246 Gene3D G3DSA:3.40.50.150 20 226 1.7E-30 T 15-10-2018 C2I28_16315 d0c8c24af5271cc674befe610586ba01 246 SUPERFAMILY SSF53335 22 233 7.93E-30 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_16315 d0c8c24af5271cc674befe610586ba01 246 Gene3D G3DSA:2.20.25.110 141 206 1.7E-30 T 15-10-2018 C2I28_16315 d0c8c24af5271cc674befe610586ba01 246 Pfam PF13489 Methyltransferase domain 23 225 3.8E-13 T 15-10-2018 C2I28_14860 39055c5528a074e67e640b63b30f2d2a 151 Gene3D G3DSA:2.30.110.10 1 150 1.5E-60 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_14860 39055c5528a074e67e640b63b30f2d2a 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 93 1.1E-7 T 15-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 C2I28_14860 39055c5528a074e67e640b63b30f2d2a 151 SUPERFAMILY SSF50475 10 146 1.19E-9 T 15-10-2018 C2I28_17895 2c88b9325942aca35e6f286cfddc36a4 144 Pfam PF00011 Hsp20/alpha crystallin family 44 139 8.3E-15 T 15-10-2018 IPR002068 Alpha crystallin/Hsp20 domain C2I28_17895 2c88b9325942aca35e6f286cfddc36a4 144 Gene3D G3DSA:2.60.40.790 9 140 5.9E-25 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_17895 2c88b9325942aca35e6f286cfddc36a4 144 SUPERFAMILY SSF49764 23 139 1.7E-24 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_18375 e941125fc0b3fce7d7777b36407ef633 190 SUPERFAMILY SSF55729 11 183 1.09E-47 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18375 e941125fc0b3fce7d7777b36407ef633 190 Pfam PF13302 Acetyltransferase (GNAT) domain 18 157 5.8E-30 T 15-10-2018 IPR000182 GNAT domain C2I28_18375 e941125fc0b3fce7d7777b36407ef633 190 Gene3D G3DSA:3.40.630.30 9 190 3.3E-48 T 15-10-2018 C2I28_00850 ee2a40d4cbd659143f2647e80d106e54 320 Pfam PF00248 Aldo/keto reductase family 15 319 4.8E-83 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_00850 ee2a40d4cbd659143f2647e80d106e54 320 SUPERFAMILY SSF51430 1 319 1.19E-105 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_00850 ee2a40d4cbd659143f2647e80d106e54 320 Gene3D G3DSA:3.20.20.100 1 320 3.2E-125 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_21310 533e266c1db852b8d97f619f79142670 473 SUPERFAMILY SSF50475 3 308 5.1E-85 T 15-10-2018 C2I28_21310 533e266c1db852b8d97f619f79142670 473 SUPERFAMILY SSF143968 311 462 4.84E-40 T 15-10-2018 C2I28_21310 533e266c1db852b8d97f619f79142670 473 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 441 2.5E-153 T 15-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 C2I28_21310 533e266c1db852b8d97f619f79142670 473 Hamap MF_01985 Phenolic acid decarboxylase subunit C. 1 472 73.112 T 15-10-2018 IPR032902 Phenolic acid decarboxylase subunit C GO:0016831 C2I28_21310 533e266c1db852b8d97f619f79142670 473 Gene3D G3DSA:3.40.1670.10 326 440 3.0E-27 T 15-10-2018 C2I28_21310 533e266c1db852b8d97f619f79142670 473 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 415 2.2E-114 T 15-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 C2I28_04670 36e4c0660fcfe2df77286d3fd24fbe7f 254 Gene3D G3DSA:3.40.50.720 1 253 2.2E-80 T 15-10-2018 C2I28_04670 36e4c0660fcfe2df77286d3fd24fbe7f 254 SUPERFAMILY SSF69572 4 244 4.71E-62 T 15-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I28_04670 36e4c0660fcfe2df77286d3fd24fbe7f 254 Pfam PF00899 ThiF family 6 158 7.5E-38 T 15-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 PIRSF PIRSF000850 98 285 0.0019 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 PIRSF PIRSF000850 290 399 0.008 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 PIRSF PIRSF000850 390 482 0.12 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 SMART SM00155 219 246 3.8E-6 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 SMART SM00155 396 423 1.9E-6 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 SUPERFAMILY SSF56024 272 469 7.63E-49 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 Pfam PF13396 Phospholipase_D-nuclease N-terminal 17 59 1.3E-10 T 15-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 SUPERFAMILY SSF56024 100 312 1.37E-54 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 Gene3D G3DSA:3.30.870.10 315 456 1.6E-25 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 Hamap MF_01916 Cardiolipin synthase. 11 483 43.957 T 15-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 Gene3D G3DSA:3.30.870.10 115 314 8.4E-47 T 15-10-2018 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 Pfam PF13091 PLD-like domain 324 450 5.6E-27 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 Pfam PF13091 PLD-like domain 137 279 4.5E-15 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_10560 a8b8717d29c72bd615b3efa9bd80b6ec 483 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 7 483 1.3E-176 T 15-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I28_24835 834dc24666c1edaa874aa27bec03bd2d 211 SUPERFAMILY SSF52218 1 211 1.93E-47 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24835 834dc24666c1edaa874aa27bec03bd2d 211 Pfam PF02525 Flavodoxin-like fold 3 204 4.8E-42 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_24835 834dc24666c1edaa874aa27bec03bd2d 211 Gene3D G3DSA:3.40.50.360 1 211 2.2E-57 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24835 834dc24666c1edaa874aa27bec03bd2d 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 26.943 T 15-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I28_19145 b1c5aac72a8b31c5c74a330f695e8b7e 342 Gene3D G3DSA:3.40.50.12110 3 115 1.2E-45 T 15-10-2018 C2I28_19145 b1c5aac72a8b31c5c74a330f695e8b7e 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 5.7E-156 T 15-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 C2I28_19145 b1c5aac72a8b31c5c74a330f695e8b7e 342 SUPERFAMILY SSF102114 85 231 6.15E-5 T 15-10-2018 C2I28_19145 b1c5aac72a8b31c5c74a330f695e8b7e 342 Gene3D G3DSA:3.80.30.30 116 342 3.3E-91 T 15-10-2018 C2I28_22410 4baae09bdd4c40965264771003b3fe3a 274 Pfam PF03618 Kinase/pyrophosphorylase 7 262 3.0E-98 T 15-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 C2I28_22410 4baae09bdd4c40965264771003b3fe3a 274 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 5 267 59.889 T 15-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein C2I28_07525 de92a8d941f92c88d402419278f10043 149 SUPERFAMILY SSF50814 10 146 1.71E-33 T 15-10-2018 IPR012674 Calycin C2I28_07525 de92a8d941f92c88d402419278f10043 149 Gene3D G3DSA:2.40.128.20 2 149 1.5E-43 T 15-10-2018 IPR012674 Calycin C2I28_07525 de92a8d941f92c88d402419278f10043 149 Pfam PF09148 Domain of unknown function (DUF1934) 16 142 2.5E-32 T 15-10-2018 IPR015231 Protein of unknown function DUF1934 C2I28_08325 624c6d3a379c9b7aacb16dc521b7233e 77 Pfam PF06257 Biofilm formation stimulator VEG 4 75 2.2E-31 T 15-10-2018 IPR009366 Protein Veg GO:0006355 C2I28_08325 624c6d3a379c9b7aacb16dc521b7233e 77 Gene3D G3DSA:2.30.30.100 1 77 2.0E-27 T 15-10-2018 C2I28_08325 624c6d3a379c9b7aacb16dc521b7233e 77 PIRSF PIRSF037257 1 77 5.6E-36 T 15-10-2018 IPR009366 Protein Veg GO:0006355 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 6.7E-6 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 6.7E-6 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 SMART SM00342 206 289 3.6E-23 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 SUPERFAMILY SSF46689 189 240 5.82E-7 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 SUPERFAMILY SSF51182 37 109 7.41E-11 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 Pfam PF02311 AraC-like ligand binding domain 39 104 2.8E-10 T 15-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 SUPERFAMILY SSF46689 242 292 3.27E-12 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 Gene3D G3DSA:1.10.10.60 187 239 2.9E-12 T 15-10-2018 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 Gene3D G3DSA:2.60.120.10 8 104 2.8E-10 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 Gene3D G3DSA:1.10.10.60 240 294 2.6E-16 T 15-10-2018 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 Pfam PF12833 Helix-turn-helix domain 213 290 1.0E-16 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_24370 d8c5a7f2ba1a1d9e71af357a3472c94c 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 285 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 SUPERFAMILY SSF46785 14 139 2.15E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 Gene3D G3DSA:1.10.287.100 99 150 1.2E-11 T 15-10-2018 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 Gene3D G3DSA:1.10.10.10 35 98 1.2E-19 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 Pfam PF01047 MarR family 35 93 5.8E-16 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 Gene3D G3DSA:1.20.5.420 3 33 1.2E-5 T 15-10-2018 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 SMART SM00347 28 128 3.3E-25 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 3.2E-9 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 3.2E-9 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.2E-9 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_23610 204695fcb269248c9ec9e9cd7f55120a 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.2E-9 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 SMART SM00091 218 284 1.0E-4 T 15-10-2018 IPR000014 PAS domain C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 426 528 1.2E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 489 4.6E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 527 4.6E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 4.6E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 508 4.6E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 Gene3D G3DSA:3.30.450.20 35 168 7.8E-27 T 15-10-2018 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 325 378 5.2E-10 T 15-10-2018 IPR039506 SpoOB, alpha-helical domain C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 SUPERFAMILY SSF55874 399 527 4.85E-28 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 SUPERFAMILY SSF55890 329 377 2.09E-9 T 15-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 Pfam PF17203 Single cache domain 3 41 172 7.2E-13 T 15-10-2018 IPR033463 Single cache domain 3 C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 SMART SM00387 422 529 5.4E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 Gene3D G3DSA:3.30.565.10 385 529 1.3E-28 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 SUPERFAMILY SSF55785 218 314 4.36E-8 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 SUPERFAMILY SSF103190 42 172 9.81E-23 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_12450 19b65a5829205112571d8b3e7097a6d2 529 Gene3D G3DSA:3.30.450.20 204 317 5.5E-25 T 15-10-2018 C2I28_00230 ae9e9fc84ac87f0ebce01e1c4e167974 77 Gene3D G3DSA:1.20.140.150 1 76 3.7E-5 T 15-10-2018 C2I28_27290 caa351d52b54a32e7781f7d35009e2d8 223 Pfam PF03567 Sulfotransferase family 2 211 6.9E-15 T 15-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 C2I28_27290 caa351d52b54a32e7781f7d35009e2d8 223 Gene3D G3DSA:3.40.50.300 1 222 6.0E-23 T 15-10-2018 C2I28_27290 caa351d52b54a32e7781f7d35009e2d8 223 SUPERFAMILY SSF52540 4 120 7.36E-10 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_27690 caa351d52b54a32e7781f7d35009e2d8 223 Pfam PF03567 Sulfotransferase family 2 211 6.9E-15 T 15-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 C2I28_27690 caa351d52b54a32e7781f7d35009e2d8 223 Gene3D G3DSA:3.40.50.300 1 222 6.0E-23 T 15-10-2018 C2I28_27690 caa351d52b54a32e7781f7d35009e2d8 223 SUPERFAMILY SSF52540 4 120 7.36E-10 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20520 b184079652885acf2b42cb1359fbfd99 143 SUPERFAMILY SSF54593 2 137 2.29E-35 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_20520 b184079652885acf2b42cb1359fbfd99 143 Gene3D G3DSA:3.10.180.10 9 143 6.3E-45 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_20520 b184079652885acf2b42cb1359fbfd99 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 135 1.2E-9 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_06760 0d30846a0bac91ba8991e5dfc654e1b2 114 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 6 111 3.0E-32 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_07585 1a2f325d1b764febf552d12e8cfb666b 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 8 319 3.4E-127 T 15-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I28_07585 1a2f325d1b764febf552d12e8cfb666b 323 Gene3D G3DSA:3.40.50.10750 142 295 4.3E-133 T 15-10-2018 C2I28_07585 1a2f325d1b764febf552d12e8cfb666b 323 PIRSF PIRSF000428 1 323 2.3E-109 T 15-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I28_07585 1a2f325d1b764febf552d12e8cfb666b 323 Gene3D G3DSA:3.40.50.10950 19 319 4.3E-133 T 15-10-2018 C2I28_07585 1a2f325d1b764febf552d12e8cfb666b 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 8.8E-126 T 15-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I28_07585 1a2f325d1b764febf552d12e8cfb666b 323 SUPERFAMILY SSF53659 6 322 1.89E-92 T 15-10-2018 C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 Gene3D G3DSA:2.40.100.10 110 250 2.6E-62 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 Gene3D G3DSA:3.30.1360.40 6 108 1.9E-26 T 15-10-2018 C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 15 233 1.7E-81 T 15-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 SUPERFAMILY SSF50891 112 241 4.93E-49 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 SMART SM00796 10 225 8.7E-99 T 15-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 12 225 2.9E-75 T 15-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I28_20440 66530dcf301e30778f3198c4ce5c8879 251 SUPERFAMILY SSF160467 12 116 7.06E-14 T 15-10-2018 C2I28_16725 2e26fef48c044db411bd395eaf0f7548 125 Pfam PF01638 HxlR-like helix-turn-helix 28 117 6.0E-27 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_16725 2e26fef48c044db411bd395eaf0f7548 125 SUPERFAMILY SSF46785 17 118 3.77E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16725 2e26fef48c044db411bd395eaf0f7548 125 Gene3D G3DSA:1.10.10.10 10 123 1.4E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 PRINTS PR00116 Arginase signature 131 146 1.4E-6 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 PRINTS PR00116 Arginase signature 247 276 1.4E-6 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 PIRSF PIRSF036979 25 327 2.2E-51 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 SUPERFAMILY SSF52768 31 325 1.62E-65 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 TIGRFAM TIGR01227 hutG: formimidoylglutamase 17 320 3.9E-69 T 15-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 Gene3D G3DSA:3.40.800.10 34 325 5.9E-78 T 15-10-2018 C2I28_16015 8ab8a391f7e61fbe33c0ab36883fd091 327 Pfam PF00491 Arginase family 44 319 4.3E-60 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_06225 edca9260eeb08e9fb9f0a427b2e86416 262 SUPERFAMILY SSF51735 114 251 6.79E-15 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06225 edca9260eeb08e9fb9f0a427b2e86416 262 Gene3D G3DSA:3.40.50.720 111 252 5.7E-24 T 15-10-2018 C2I28_06225 edca9260eeb08e9fb9f0a427b2e86416 262 Pfam PF07885 Ion channel 24 95 6.8E-14 T 15-10-2018 IPR013099 Potassium channel domain C2I28_06225 edca9260eeb08e9fb9f0a427b2e86416 262 Gene3D G3DSA:1.10.287.70 3 97 1.9E-18 T 15-10-2018 C2I28_06225 edca9260eeb08e9fb9f0a427b2e86416 262 SUPERFAMILY SSF81324 8 136 4.06E-22 T 15-10-2018 C2I28_06225 edca9260eeb08e9fb9f0a427b2e86416 262 Pfam PF02254 TrkA-N domain 116 238 7.2E-11 T 15-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 SUPERFAMILY SSF103473 5 524 6.93E-78 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 445 6.1E-87 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 Pfam PF07690 Major Facilitator Superfamily 16 407 1.1E-54 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 Gene3D G3DSA:1.20.1250.20 254 426 2.7E-24 T 15-10-2018 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 6.4E-14 T 15-10-2018 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 6.4E-14 T 15-10-2018 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 6.4E-14 T 15-10-2018 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 6.4E-14 T 15-10-2018 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 6.4E-14 T 15-10-2018 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_23605 e6d32fe8fd898c8eb3b0abe54701b0a4 535 Gene3D G3DSA:1.20.1720.10 12 197 8.6E-49 T 15-10-2018 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 SUPERFAMILY SSF53756 4 473 1.43E-129 T 15-10-2018 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 Gene3D G3DSA:3.40.50.2000 3 469 5.2E-185 T 15-10-2018 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 Pfam PF08323 Starch synthase catalytic domain 2 234 6.0E-86 T 15-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 Gene3D G3DSA:3.40.50.2000 247 455 5.2E-185 T 15-10-2018 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 470 8.4E-178 T 15-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 Hamap MF_00484 Glycogen synthase [glgA]. 1 471 46.479 T 15-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 C2I28_06030 03273c18dfc24101a1f9fdaf93efbdc9 476 Pfam PF00534 Glycosyl transferases group 1 285 434 4.6E-15 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_08565 9ce9441201e8acfa4bb5d7c705f4c895 159 Pfam PF02542 YgbB family 3 156 8.9E-68 T 15-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I28_08565 9ce9441201e8acfa4bb5d7c705f4c895 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4 157 2.3E-72 T 15-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I28_08565 9ce9441201e8acfa4bb5d7c705f4c895 159 Gene3D G3DSA:3.30.1330.50 1 159 1.6E-71 T 15-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I28_08565 9ce9441201e8acfa4bb5d7c705f4c895 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 3 158 37.697 T 15-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I28_08565 9ce9441201e8acfa4bb5d7c705f4c895 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 37 52 - T 15-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I28_08565 9ce9441201e8acfa4bb5d7c705f4c895 159 SUPERFAMILY SSF69765 1 158 4.19E-68 T 15-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 C2I28_18360 22292fc98744a2c1ee77e5977fbe65ca 230 Pfam PF04172 LrgB-like family 14 225 7.7E-69 T 15-10-2018 IPR007300 CidB/LrgB family C2I28_00515 6b7a133ea027eedb9a212ffc02d5e1de 90 Pfam PF13119 Domain of unknown function (DUF3973) 1 40 4.5E-15 T 15-10-2018 IPR025003 Domain of unknown function DUF3973 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 Gene3D G3DSA:2.40.30.10 149 253 1.7E-33 T 15-10-2018 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 Pfam PF00970 Oxidoreductase FAD-binding domain 156 252 6.6E-9 T 15-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 Pfam PF00042 Globin 6 101 1.9E-11 T 15-10-2018 IPR000971 Globin GO:0020037 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 Gene3D G3DSA:3.40.50.80 255 390 8.3E-32 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 SUPERFAMILY SSF46458 3 142 3.49E-41 T 15-10-2018 IPR009050 Globin-like superfamily C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 SUPERFAMILY SSF63380 148 254 5.62E-27 T 15-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 SUPERFAMILY SSF52343 253 385 5.11E-30 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 Pfam PF00175 Oxidoreductase NAD-binding domain 262 364 6.7E-16 T 15-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 182 194 3.6E-9 T 15-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 351 359 3.6E-9 T 15-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 261 280 3.6E-9 T 15-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 Gene3D G3DSA:1.10.490.10 1 144 1.0E-56 T 15-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 227 236 9.7E-7 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 261 280 9.7E-7 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 182 192 9.7E-7 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_09900 90482c59bc86a9ee778f171a095ef35a 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 351 359 9.7E-7 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_15210 30f49e15c414b9240baddf44823fea65 348 PIRSF PIRSF037431 2 347 3.9E-123 T 15-10-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 C2I28_15210 30f49e15c414b9240baddf44823fea65 348 Pfam PF07730 Histidine kinase 145 212 2.2E-16 T 15-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I28_15210 30f49e15c414b9240baddf44823fea65 348 SUPERFAMILY SSF55874 221 339 4.58E-15 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_15210 30f49e15c414b9240baddf44823fea65 348 SMART SM00387 248 341 2.9E-5 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_15210 30f49e15c414b9240baddf44823fea65 348 Gene3D G3DSA:3.30.565.10 210 345 1.1E-27 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_23770 4871c7e3ae4691bf01ecab37c87c5afe 115 Gene3D G3DSA:3.40.250.10 24 110 3.2E-7 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_23770 4871c7e3ae4691bf01ecab37c87c5afe 115 SUPERFAMILY SSF52821 11 105 3.09E-7 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_17135 e84324577f4ee120f322018567efb7f0 296 Pfam PF00701 Dihydrodipicolinate synthetase family 3 287 7.5E-84 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 SUPERFAMILY SSF51569 3 288 8.69E-91 T 15-10-2018 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 289 41.909 T 15-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 8.3E-27 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 8.3E-27 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 8.3E-27 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 8.3E-27 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 15-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 SMART SM01130 2 291 2.0E-108 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 287 8.7E-74 T 15-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 Gene3D G3DSA:3.20.20.70 1 290 1.6E-97 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_17135 e84324577f4ee120f322018567efb7f0 296 PIRSF PIRSF001365 1 296 8.4E-88 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02685 0104d44be27c814b339c23deda283fd4 187 SUPERFAMILY SSF46785 5 52 1.21E-6 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_02685 0104d44be27c814b339c23deda283fd4 187 Gene3D G3DSA:1.10.10.10 1 60 4.6E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02685 0104d44be27c814b339c23deda283fd4 187 PIRSF PIRSF037733 1 187 1.2E-85 T 15-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 C2I28_02685 0104d44be27c814b339c23deda283fd4 187 SUPERFAMILY SSF54637 74 181 9.49E-25 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_02685 0104d44be27c814b339c23deda283fd4 187 Gene3D G3DSA:3.10.129.10 68 185 1.7E-38 T 15-10-2018 C2I28_02685 0104d44be27c814b339c23deda283fd4 187 Hamap MF_01814 Transcription factor FapR [fapR]. 1 186 39.201 T 15-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 C2I28_02685 0104d44be27c814b339c23deda283fd4 187 Pfam PF08279 HTH domain 8 39 1.9E-4 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_02685 0104d44be27c814b339c23deda283fd4 187 Pfam PF03061 Thioesterase superfamily 112 169 1.6E-6 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_01300 0c128e5de82bd4c1cc9273535b47dfc8 640 SUPERFAMILY SSF53649 243 634 2.8E-78 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_01300 0c128e5de82bd4c1cc9273535b47dfc8 640 Gene3D G3DSA:3.40.720.10 237 546 6.9E-79 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_01300 0c128e5de82bd4c1cc9273535b47dfc8 640 PIRSF PIRSF005091 1 619 2.1E-195 T 15-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I28_01300 0c128e5de82bd4c1cc9273535b47dfc8 640 Pfam PF00884 Sulfatase 245 536 1.1E-32 T 15-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 SMART SM00663 224 503 2.9E-186 T 15-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Gene3D G3DSA:1.10.132.30 657 794 7.3E-58 T 15-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 15-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.655 T 15-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 SUPERFAMILY SSF64484 5 1191 0.0 T 15-10-2018 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Gene3D G3DSA:1.10.40.90 363 405 7.9E-24 T 15-10-2018 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Gene3D G3DSA:1.10.274.100 479 656 5.6E-46 T 15-10-2018 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1129 1.4E-67 T 15-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 8.7E-89 T 15-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Gene3D G3DSA:2.40.50.100 966 1029 4.0E-67 T 15-10-2018 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Gene3D G3DSA:1.10.1790.20 950 1128 4.0E-67 T 15-10-2018 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 474 2.7E-38 T 15-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 1.1E-36 T 15-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 760 4.7E-14 T 15-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_08650 a33f3ed0d31a8fe127ffb51f8368c113 1197 Gene3D G3DSA:1.10.150.390 1130 1192 6.7E-29 T 15-10-2018 C2I28_06705 39b4b8836172bacee46cf4b189f03a58 208 Pfam PF01569 PAP2 superfamily 59 170 1.3E-21 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_06705 39b4b8836172bacee46cf4b189f03a58 208 SMART SM00014 58 166 1.1E-16 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_06705 39b4b8836172bacee46cf4b189f03a58 208 SUPERFAMILY SSF48317 2 178 3.01E-37 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_06705 39b4b8836172bacee46cf4b189f03a58 208 Gene3D G3DSA:1.20.144.10 92 179 4.3E-18 T 15-10-2018 C2I28_06705 39b4b8836172bacee46cf4b189f03a58 208 Gene3D G3DSA:1.20.144.10 3 91 7.4E-7 T 15-10-2018 C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Gene3D G3DSA:3.30.750.140 723 839 4.8E-9 T 15-10-2018 IPR038610 FliK-like, C-terminal domain superfamily C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Gene3D G3DSA:3.30.750.140 282 398 2.0E-10 T 15-10-2018 IPR038610 FliK-like, C-terminal domain superfamily C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Gene3D G3DSA:3.30.750.140 546 650 1.7E-9 T 15-10-2018 IPR038610 FliK-like, C-terminal domain superfamily C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Gene3D G3DSA:3.30.750.140 417 523 3.9E-11 T 15-10-2018 IPR038610 FliK-like, C-terminal domain superfamily C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Pfam PF02120 Flagellar hook-length control protein FliK 442 511 3.2E-13 T 15-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Pfam PF02120 Flagellar hook-length control protein FliK 567 635 1.4E-10 T 15-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Pfam PF02120 Flagellar hook-length control protein FliK 747 819 4.3E-10 T 15-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal C2I28_02500 5310eaae69e0f95b84c8ccf2a7a6d039 872 Pfam PF02120 Flagellar hook-length control protein FliK 316 381 1.4E-11 T 15-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 SUPERFAMILY SSF46689 356 449 5.55E-7 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 Gene3D G3DSA:3.30.450.20 11 137 5.1E-18 T 15-10-2018 C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 SUPERFAMILY SSF55785 18 117 5.41E-12 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 SMART SM00382 179 305 0.0016 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 Gene3D G3DSA:1.10.10.60 397 449 3.4E-5 T 15-10-2018 C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 183 196 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 19 128 6.2E-13 T 15-10-2018 IPR000014 PAS domain C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 Gene3D G3DSA:1.10.8.60 314 393 1.2E-20 T 15-10-2018 C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 SUPERFAMILY SSF52540 163 385 2.47E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 Gene3D G3DSA:3.40.50.300 158 313 7.1E-39 T 15-10-2018 C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 SMART SM00091 17 84 2.0E-4 T 15-10-2018 IPR000014 PAS domain C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 Pfam PF13426 PAS domain 28 124 4.0E-7 T 15-10-2018 IPR000014 PAS domain C2I28_12055 0c28a792ad4404f295765a4ffcb31bad 449 Pfam PF00158 Sigma-54 interaction domain 160 310 2.4E-32 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Gene3D G3DSA:3.40.50.970 1 174 1.6E-72 T 15-10-2018 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 449 4.0E-157 T 15-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 PIRSF PIRSF004983 1 580 9.5E-203 T 15-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 SUPERFAMILY SSF52467 167 377 6.41E-10 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Gene3D G3DSA:3.40.50.970 384 581 4.6E-65 T 15-10-2018 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 175 1.7E-40 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Gene3D G3DSA:3.40.50.1220 201 382 1.7E-58 T 15-10-2018 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 SUPERFAMILY SSF52518 9 178 2.36E-39 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 SUPERFAMILY SSF52518 388 576 1.9E-30 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Pfam PF16582 Middle domain of thiamine pyrophosphate 222 406 2.2E-21 T 15-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 573 37.133 T 15-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 C2I28_06005 b39e2afc0c34516e96cc5f33a54a457c 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 441 555 3.9E-10 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_25735 b02da4dc9f91d8963251f7203ec68bf7 434 Pfam PF07690 Major Facilitator Superfamily 26 390 1.2E-70 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_25735 b02da4dc9f91d8963251f7203ec68bf7 434 PIRSF PIRSF002808 2 433 2.3E-46 T 15-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I28_25735 b02da4dc9f91d8963251f7203ec68bf7 434 SUPERFAMILY SSF103473 8 429 9.42E-99 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_25735 b02da4dc9f91d8963251f7203ec68bf7 434 Gene3D G3DSA:1.20.1250.20 14 209 3.1E-56 T 15-10-2018 C2I28_25735 b02da4dc9f91d8963251f7203ec68bf7 434 Gene3D G3DSA:1.20.1250.20 226 432 1.9E-37 T 15-10-2018 C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SUPERFAMILY SSF54106 164 207 5.62E-13 T 15-10-2018 C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SMART SM00257 165 208 1.6E-16 T 15-10-2018 IPR018392 LysM domain C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SMART SM00257 28 71 1.2E-16 T 15-10-2018 IPR018392 LysM domain C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SMART SM00257 91 134 4.6E-18 T 15-10-2018 IPR018392 LysM domain C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SUPERFAMILY SSF50685 303 349 4.53E-9 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Pfam PF06725 3D domain 302 362 6.1E-21 T 15-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SUPERFAMILY SSF54106 89 134 3.66E-13 T 15-10-2018 C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Gene3D G3DSA:2.40.40.10 269 355 4.2E-7 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Pfam PF01476 LysM domain 92 133 3.2E-16 T 15-10-2018 IPR018392 LysM domain C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Pfam PF01476 LysM domain 166 207 1.6E-14 T 15-10-2018 IPR018392 LysM domain C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Pfam PF01476 LysM domain 29 70 9.0E-13 T 15-10-2018 IPR018392 LysM domain C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 SUPERFAMILY SSF54106 28 70 5.75E-11 T 15-10-2018 C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Gene3D G3DSA:3.10.350.10 87 139 1.7E-20 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Gene3D G3DSA:3.10.350.10 24 78 8.7E-18 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_19480 1be1d21420a93c927f6313dd49b4d849 363 Gene3D G3DSA:3.10.350.10 161 215 4.1E-19 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_00560 c370a6bca7e3f76c3ff932e2aeaab8d3 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.791 T 15-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00560 c370a6bca7e3f76c3ff932e2aeaab8d3 162 Gene3D G3DSA:3.30.70.640 1 162 7.2E-68 T 15-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00560 c370a6bca7e3f76c3ff932e2aeaab8d3 162 SUPERFAMILY SSF55040 11 157 8.89E-58 T 15-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00560 c370a6bca7e3f76c3ff932e2aeaab8d3 162 Pfam PF01967 MoaC family 15 152 4.6E-53 T 15-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_00560 c370a6bca7e3f76c3ff932e2aeaab8d3 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 1.1E-64 T 15-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 SUPERFAMILY SSF53738 306 457 1.92E-32 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 15-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Gene3D G3DSA:3.40.120.10 209 326 4.8E-23 T 15-10-2018 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 SUPERFAMILY SSF55957 446 579 2.88E-15 T 15-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Gene3D G3DSA:3.40.120.10 327 454 1.7E-37 T 15-10-2018 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 179 5.7E-44 T 15-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 318 4.8E-24 T 15-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 SUPERFAMILY SSF53738 30 238 2.47E-47 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 SUPERFAMILY SSF53738 208 317 1.14E-20 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Gene3D G3DSA:3.30.310.50 473 570 5.3E-11 T 15-10-2018 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 506 562 8.5E-12 T 15-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 1.6E-24 T 15-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 2.1E-8 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 2.1E-8 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 250 2.1E-8 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_10825 0fed997807d57d9568fe70e90bb7e2c7 584 Gene3D G3DSA:3.40.120.10 33 189 1.0E-49 T 15-10-2018 C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 SUPERFAMILY SSF51735 5 165 5.42E-50 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 286 1.1E-35 T 15-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 161 1.2E-52 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 Gene3D G3DSA:1.10.1040.10 165 292 1.1E-39 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 Gene3D G3DSA:3.40.50.720 2 164 4.9E-55 T 15-10-2018 C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 PIRSF PIRSF000103 1 293 1.7E-72 T 15-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I28_11615 b70401c26eb91d2f7605142fa7f5faeb 294 SUPERFAMILY SSF48179 166 289 4.08E-38 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 PIRSF PIRSF001549 1 422 1.3E-119 T 15-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 Pfam PF03129 Anticodon binding domain 331 420 9.3E-19 T 15-10-2018 IPR004154 Anticodon-binding C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 1.2E-155 T 15-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 Gene3D G3DSA:3.30.930.10 2 324 1.5E-113 T 15-10-2018 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 SUPERFAMILY SSF55681 4 318 1.9E-97 T 15-10-2018 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 Pfam PF13393 Histidyl-tRNA synthetase 8 313 4.2E-48 T 15-10-2018 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 34.082 T 15-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 Gene3D G3DSA:3.40.50.800 328 421 4.4E-29 T 15-10-2018 IPR036621 Anticodon-binding domain superfamily C2I28_04685 e0355475a37efbc1aed8a1bc2f9bf402 422 SUPERFAMILY SSF52954 328 421 8.16E-28 T 15-10-2018 C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 Pfam PF12544 Lysine-2,3-aminomutase 321 447 8.5E-61 T 15-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 PIRSF PIRSF004911 6 401 4.5E-160 T 15-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 Gene3D G3DSA:3.20.20.70 63 348 2.2E-118 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 Pfam PF13353 4Fe-4S single cluster domain 127 199 7.4E-5 T 15-10-2018 C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 SUPERFAMILY SSF102114 114 356 7.72E-34 T 15-10-2018 C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 TIGRFAM TIGR00238 TIGR00238: KamA family protein 14 342 1.4E-147 T 15-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 23 427 6.1E-193 T 15-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 Pfam PF04055 Radical SAM superfamily 130 277 3.0E-7 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_01755 a1d79472caf603644e1c30783225dd7a 470 Gene3D G3DSA:2.40.50.600 349 414 3.4E-21 T 15-10-2018 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 PIRSF PIRSF000538 3 505 3.0E-141 T 15-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 453 3.5E-36 T 15-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 249 8.1E-72 T 15-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 15-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 Gene3D G3DSA:3.30.420.40 1 250 8.1E-80 T 15-10-2018 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 SUPERFAMILY SSF53067 252 500 3.6E-68 T 15-10-2018 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 Gene3D G3DSA:3.30.420.40 251 513 2.2E-90 T 15-10-2018 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 5 509 9.7E-249 T 15-10-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 SUPERFAMILY SSF53067 4 251 3.64E-69 T 15-10-2018 C2I28_11950 6599cd9583d8c09826c2be324e412711 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 15-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 SUPERFAMILY SSF52540 31 224 9.22E-59 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 357 7.4E-146 T 15-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 Gene3D G3DSA:3.40.50.300 13 177 7.0E-107 T 15-10-2018 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 361 4.0E-14 T 15-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.0E-5 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.0E-5 T 15-10-2018 IPR001270 ClpA/B family GO:0005524 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 Gene3D G3DSA:1.20.272.10 242 362 7.5E-8 T 15-10-2018 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.4E-45 T 15-10-2018 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 SUPERFAMILY SSF48019 244 359 3.29E-23 T 15-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 Gene3D G3DSA:1.10.8.60 8 238 7.0E-107 T 15-10-2018 C2I28_08135 ba6267f0b019c22da91ad597ef690ea1 562 SMART SM00382 37 179 1.9E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 3.5E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 3.5E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 3.5E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 SMART SM00448 2 115 5.7E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 SMART SM00421 144 201 3.6E-27 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 SUPERFAMILY SSF46894 138 206 5.78E-23 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 SUPERFAMILY SSF52172 1 133 6.4E-34 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 Gene3D G3DSA:3.40.50.12740 2 207 4.9E-75 T 15-10-2018 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 Pfam PF00072 Response regulator receiver domain 4 115 2.7E-25 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 8.6E-22 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15215 f3d758d47f38207232cb0d4c60d48553 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 15-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 Pfam PF01470 Pyroglutamyl peptidase 3 198 4.9E-78 T 15-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 9.5E-48 T 15-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 9.5E-48 T 15-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 9.5E-48 T 15-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 9.5E-48 T 15-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 9.5E-48 T 15-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 SUPERFAMILY SSF53182 1 210 3.27E-69 T 15-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 210 9.0E-80 T 15-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 199 38.525 T 15-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 PIRSF PIRSF015592 1 211 2.4E-79 T 15-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 Gene3D G3DSA:3.40.630.20 1 213 1.7E-78 T 15-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 C2I28_13585 0c4508cad73e43a54764e2eece4ed74a 213 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 15-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 C2I28_10060 2f5068522c6a9d1eeccb177afba92e2d 269 Gene3D G3DSA:1.10.10.10 112 156 4.1E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_10060 2f5068522c6a9d1eeccb177afba92e2d 269 Pfam PF02631 RecX family 88 210 4.0E-31 T 15-10-2018 IPR003783 Regulatory protein RecX GO:0006282 C2I28_10060 2f5068522c6a9d1eeccb177afba92e2d 269 Hamap MF_01114 Regulatory protein RecX [recX]. 46 213 17.859 T 15-10-2018 IPR003783 Regulatory protein RecX GO:0006282 C2I28_10060 2f5068522c6a9d1eeccb177afba92e2d 269 Gene3D G3DSA:1.10.10.10 218 269 1.3E-11 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_10060 2f5068522c6a9d1eeccb177afba92e2d 269 Gene3D G3DSA:1.10.10.10 157 217 3.2E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_10060 2f5068522c6a9d1eeccb177afba92e2d 269 Gene3D G3DSA:1.10.10.2800 1 111 1.6E-36 T 15-10-2018 C2I28_22940 4c3e055c3374f74236193ed46755ae14 228 Hamap MF_01385 Urease accessory protein UreF [ureF]. 4 228 27.374 T 15-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 C2I28_22940 4c3e055c3374f74236193ed46755ae14 228 PIRSF PIRSF009467 1 228 1.0E-76 T 15-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 C2I28_22940 4c3e055c3374f74236193ed46755ae14 228 Pfam PF01730 UreF 36 183 6.4E-29 T 15-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 C2I28_22940 4c3e055c3374f74236193ed46755ae14 228 Gene3D G3DSA:1.10.4190.10 1 206 3.5E-66 T 15-10-2018 IPR038277 UreF domain superfamily C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 Gene3D G3DSA:1.20.58.340 238 315 8.1E-33 T 15-10-2018 C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 Pfam PF01544 CorA-like Mg2+ transporter protein 28 311 3.8E-78 T 15-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 Gene3D G3DSA:1.20.58.340 125 237 2.1E-31 T 15-10-2018 C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 SUPERFAMILY SSF143865 1 249 3.53E-64 T 15-10-2018 C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 10 315 1.1E-98 T 15-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 SUPERFAMILY SSF144083 250 313 6.67E-22 T 15-10-2018 C2I28_22590 a458a0b2349e395e186f2a426832ec99 320 Gene3D G3DSA:3.30.460.20 8 124 1.2E-30 T 15-10-2018 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 SUPERFAMILY SSF63520 824 925 4.32E-16 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Gene3D G3DSA:3.40.50.300 105 288 5.1E-42 T 15-10-2018 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 208 223 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 SUPERFAMILY SSF53062 572 686 1.57E-18 T 15-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Pfam PF03610 PTS system fructose IIA component 574 674 1.4E-11 T 15-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Pfam PF00874 PRD domain 841 925 8.0E-14 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Pfam PF00874 PRD domain 477 563 4.3E-15 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Gene3D G3DSA:1.10.1790.10 467 566 2.9E-15 T 15-10-2018 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Gene3D G3DSA:1.10.1790.10 831 927 4.8E-11 T 15-10-2018 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 SUPERFAMILY SSF46785 21 68 1.54E-5 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Gene3D G3DSA:3.40.50.510 569 705 5.1E-37 T 15-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 SUPERFAMILY SSF63520 461 564 1.24E-18 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 SMART SM00382 135 289 2.3E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 Pfam PF00158 Sigma-54 interaction domain 112 278 7.4E-48 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_15905 f9835c69e8ec34faef59be8ebbd529f6 928 SUPERFAMILY SSF52540 126 347 2.26E-38 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11115 9669ca1eb90ff692aa0a107c64cc4d81 247 Gene3D G3DSA:3.40.50.300 3 246 1.7E-63 T 15-10-2018 C2I28_11115 9669ca1eb90ff692aa0a107c64cc4d81 247 SUPERFAMILY SSF52540 4 233 5.97E-57 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11115 9669ca1eb90ff692aa0a107c64cc4d81 247 SMART SM00382 29 211 7.3E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11115 9669ca1eb90ff692aa0a107c64cc4d81 247 Pfam PF00005 ABC transporter 20 163 1.4E-29 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_26335 50b3f7248ccfe77800d7ba3481d56b50 144 Pfam PF01381 Helix-turn-helix 21 64 8.4E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26335 50b3f7248ccfe77800d7ba3481d56b50 144 Gene3D G3DSA:1.10.260.40 8 108 1.5E-17 T 15-10-2018 C2I28_26335 50b3f7248ccfe77800d7ba3481d56b50 144 SUPERFAMILY SSF47413 4 70 5.63E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_26335 50b3f7248ccfe77800d7ba3481d56b50 144 SMART SM00530 11 66 1.0E-9 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27085 50b3f7248ccfe77800d7ba3481d56b50 144 Pfam PF01381 Helix-turn-helix 21 64 8.4E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27085 50b3f7248ccfe77800d7ba3481d56b50 144 Gene3D G3DSA:1.10.260.40 8 108 1.5E-17 T 15-10-2018 C2I28_27085 50b3f7248ccfe77800d7ba3481d56b50 144 SUPERFAMILY SSF47413 4 70 5.63E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_27085 50b3f7248ccfe77800d7ba3481d56b50 144 SMART SM00530 11 66 1.0E-9 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26235 50b3f7248ccfe77800d7ba3481d56b50 144 Pfam PF01381 Helix-turn-helix 21 64 8.4E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26235 50b3f7248ccfe77800d7ba3481d56b50 144 Gene3D G3DSA:1.10.260.40 8 108 1.5E-17 T 15-10-2018 C2I28_26235 50b3f7248ccfe77800d7ba3481d56b50 144 SUPERFAMILY SSF47413 4 70 5.63E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_26235 50b3f7248ccfe77800d7ba3481d56b50 144 SMART SM00530 11 66 1.0E-9 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27185 50b3f7248ccfe77800d7ba3481d56b50 144 Pfam PF01381 Helix-turn-helix 21 64 8.4E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_27185 50b3f7248ccfe77800d7ba3481d56b50 144 Gene3D G3DSA:1.10.260.40 8 108 1.5E-17 T 15-10-2018 C2I28_27185 50b3f7248ccfe77800d7ba3481d56b50 144 SUPERFAMILY SSF47413 4 70 5.63E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_27185 50b3f7248ccfe77800d7ba3481d56b50 144 SMART SM00530 11 66 1.0E-9 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_12515 1e09708c3419b78cd7826a54615b8fe7 459 Pfam PF13520 Amino acid permease 12 407 9.8E-39 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_12515 1e09708c3419b78cd7826a54615b8fe7 459 PIRSF PIRSF006060 2 448 9.1E-77 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_12515 1e09708c3419b78cd7826a54615b8fe7 459 Gene3D G3DSA:1.20.1740.10 7 452 1.9E-77 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 Gene3D G3DSA:3.50.50.60 163 285 1.1E-110 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 2.4E-174 T 15-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 3.5E-37 T 15-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 15-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 SUPERFAMILY SSF55424 350 472 4.64E-40 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 2.5E-66 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 Gene3D G3DSA:3.50.50.60 5 341 1.1E-110 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PIRSF PIRSF000350 1 469 1.0E-83 T 15-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 SUPERFAMILY SSF51905 3 344 3.42E-56 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 Gene3D G3DSA:3.30.390.30 353 473 2.7E-45 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.7E-36 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.7E-36 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.7E-36 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-36 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.7E-36 T 15-10-2018 C2I28_03765 da5f045158d3cdf99c084bc6f5b2520c 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 1.2E-61 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_15545 020521a061bcd1d3823cb953eab6d1ef 400 Gene3D G3DSA:3.40.50.2000 5 392 3.8E-118 T 15-10-2018 C2I28_15545 020521a061bcd1d3823cb953eab6d1ef 400 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 159 373 1.7E-18 T 15-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 C2I28_15545 020521a061bcd1d3823cb953eab6d1ef 400 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 395 7.8E-109 T 15-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 C2I28_15545 020521a061bcd1d3823cb953eab6d1ef 400 SUPERFAMILY SSF53756 1 392 2.23E-73 T 15-10-2018 C2I28_15545 020521a061bcd1d3823cb953eab6d1ef 400 Gene3D G3DSA:3.40.50.2000 218 381 3.8E-118 T 15-10-2018 C2I28_07455 2749c3571b0f6d799350537b46da28eb 124 SMART SM00448 4 115 1.4E-33 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07455 2749c3571b0f6d799350537b46da28eb 124 Pfam PF00072 Response regulator receiver domain 6 115 2.6E-32 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07455 2749c3571b0f6d799350537b46da28eb 124 Gene3D G3DSA:3.40.50.2300 2 124 2.7E-43 T 15-10-2018 C2I28_07455 2749c3571b0f6d799350537b46da28eb 124 SUPERFAMILY SSF52172 5 120 7.68E-38 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 SMART SM00487 619 803 4.2E-27 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 Gene3D G3DSA:1.20.120.850 844 1062 8.5E-89 T 15-10-2018 C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 SMART SM00490 930 1012 1.1E-27 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 Gene3D G3DSA:3.40.50.300 830 1026 8.5E-89 T 15-10-2018 C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 Pfam PF00271 Helicase conserved C-terminal domain 901 1012 2.6E-23 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 Pfam PF00176 SNF2 family N-terminal domain 638 890 2.3E-54 T 15-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 SUPERFAMILY SSF52540 824 1067 3.87E-74 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 Pfam PF08455 Bacterial SNF2 helicase associated 241 616 1.3E-93 T 15-10-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 SUPERFAMILY SSF52540 606 822 1.93E-50 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20600 e86d77e13bbdb67f872b74803ede469c 1068 Gene3D G3DSA:3.40.50.10810 593 829 2.1E-60 T 15-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily C2I28_01695 a7e4a21e4fd66ede0c6c5a4479dce24f 234 Pfam PF01048 Phosphorylase superfamily 16 218 1.7E-40 T 15-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I28_01695 a7e4a21e4fd66ede0c6c5a4479dce24f 234 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 231 8.9E-109 T 15-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 C2I28_01695 a7e4a21e4fd66ede0c6c5a4479dce24f 234 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 233 47.859 T 15-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 C2I28_01695 a7e4a21e4fd66ede0c6c5a4479dce24f 234 Gene3D G3DSA:3.40.50.1580 1 233 4.1E-74 T 15-10-2018 C2I28_01695 a7e4a21e4fd66ede0c6c5a4479dce24f 234 SUPERFAMILY SSF53167 2 232 4.32E-90 T 15-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I28_01695 a7e4a21e4fd66ede0c6c5a4479dce24f 234 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 15-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_08530 dd4d13ef31719c8f2f8900a499b9d98e 180 SUPERFAMILY SSF46600 134 172 5.89E-6 T 15-10-2018 IPR036876 UVR domain superfamily C2I28_08530 dd4d13ef31719c8f2f8900a499b9d98e 180 Pfam PF02151 UvrB/uvrC motif 136 170 3.8E-6 T 15-10-2018 IPR001943 UVR domain GO:0005515 C2I28_08530 dd4d13ef31719c8f2f8900a499b9d98e 180 PIRSF PIRSF015034 1 179 6.6E-69 T 15-10-2018 IPR025542 YacH protein C2I28_12900 145de77b4255c4285b63b8d2311656bf 195 SUPERFAMILY SSF53254 2 195 6.42E-53 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_12900 145de77b4255c4285b63b8d2311656bf 195 Gene3D G3DSA:3.40.50.1240 1 195 3.0E-57 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_12900 145de77b4255c4285b63b8d2311656bf 195 SMART SM00855 1 152 2.4E-26 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_12900 145de77b4255c4285b63b8d2311656bf 195 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 4 13 - T 15-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 C2I28_12900 145de77b4255c4285b63b8d2311656bf 195 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 190 1.7E-54 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_12900 145de77b4255c4285b63b8d2311656bf 195 PIRSF PIRSF000709 1 153 2.3E-6 T 15-10-2018 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 15-10-2018 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 SUPERFAMILY SSF47413 4 62 5.28E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 6.3E-19 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 SMART SM00354 4 74 6.2E-28 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 Gene3D G3DSA:1.10.260.40 3 63 1.2E-22 T 15-10-2018 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 Gene3D G3DSA:3.40.50.2300 167 337 2.5E-67 T 15-10-2018 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 SUPERFAMILY SSF53822 82 341 5.44E-64 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 Pfam PF13377 Periplasmic binding protein-like domain 177 339 5.5E-35 T 15-10-2018 C2I28_18560 dbb27eb47cac720befd3c25cd00088df 343 Gene3D G3DSA:3.40.50.2300 83 331 2.5E-67 T 15-10-2018 C2I28_07260 17e684744d2f12dde89a7ff161d5af29 144 Gene3D G3DSA:3.10.129.10 1 144 1.1E-60 T 15-10-2018 C2I28_07260 17e684744d2f12dde89a7ff161d5af29 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 2.0E-59 T 15-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_07260 17e684744d2f12dde89a7ff161d5af29 144 Pfam PF07977 FabA-like domain 11 133 3.2E-37 T 15-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_07260 17e684744d2f12dde89a7ff161d5af29 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 35.632 T 15-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_07260 17e684744d2f12dde89a7ff161d5af29 144 SUPERFAMILY SSF54637 1 138 5.44E-49 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 SUPERFAMILY SSF52518 14 185 7.86E-60 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 206 341 5.3E-48 T 15-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 Gene3D G3DSA:3.40.50.1220 201 365 4.0E-63 T 15-10-2018 C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 Gene3D G3DSA:3.40.50.970 11 187 6.3E-68 T 15-10-2018 C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 545 1.7E-51 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 17 179 1.1E-53 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 17 570 1.0E-266 T 15-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 SUPERFAMILY SSF52467 201 367 4.19E-63 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 SUPERFAMILY SSF52518 376 570 3.4E-70 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_05050 b0cf71db259d913d60b739b2f70262f1 572 Gene3D G3DSA:3.40.50.970 369 571 6.2E-72 T 15-10-2018 C2I28_22365 d9829ef1f62c0b318574083d131f1b61 507 PIRSF PIRSF002741 1 507 5.2E-84 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_22365 d9829ef1f62c0b318574083d131f1b61 507 Gene3D G3DSA:3.10.105.10 257 464 2.7E-128 T 15-10-2018 C2I28_22365 d9829ef1f62c0b318574083d131f1b61 507 SUPERFAMILY SSF53850 34 499 1.23E-102 T 15-10-2018 C2I28_22365 d9829ef1f62c0b318574083d131f1b61 507 Gene3D G3DSA:3.40.190.10 53 256 2.7E-128 T 15-10-2018 C2I28_22365 d9829ef1f62c0b318574083d131f1b61 507 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 426 3.4E-74 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_11735 77ff5a059d4b80dcea860db38208cfe0 467 Pfam PF13520 Amino acid permease 7 428 1.3E-51 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_11735 77ff5a059d4b80dcea860db38208cfe0 467 PIRSF PIRSF006060 1 463 4.8E-53 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_11735 77ff5a059d4b80dcea860db38208cfe0 467 Gene3D G3DSA:1.20.1740.10 1 466 5.4E-61 T 15-10-2018 C2I28_06630 bf590aa4e26d8ca44f7bbfd1e36c8c32 334 Pfam PF01032 FecCD transport family 19 329 8.4E-93 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_06630 bf590aa4e26d8ca44f7bbfd1e36c8c32 334 SUPERFAMILY SSF81345 5 329 3.01E-81 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_06630 bf590aa4e26d8ca44f7bbfd1e36c8c32 334 Gene3D G3DSA:1.10.3470.10 6 333 5.0E-92 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_07025 011eb3056ca3430aa1d1af5340d1ecce 228 Gene3D G3DSA:3.40.50.300 1 224 2.1E-67 T 15-10-2018 C2I28_07025 011eb3056ca3430aa1d1af5340d1ecce 228 SMART SM00382 27 214 2.0E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_07025 011eb3056ca3430aa1d1af5340d1ecce 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 4.4E-90 T 15-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 C2I28_07025 011eb3056ca3430aa1d1af5340d1ecce 228 Pfam PF00005 ABC transporter 19 165 2.4E-36 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_07025 011eb3056ca3430aa1d1af5340d1ecce 228 SUPERFAMILY SSF52540 1 220 5.45E-73 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07025 011eb3056ca3430aa1d1af5340d1ecce 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 SUPERFAMILY SSF52172 3 122 2.13E-34 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 SMART SM00448 2 112 8.6E-30 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 3.8E-21 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 SMART SM00862 148 223 1.0E-15 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 Gene3D G3DSA:1.10.10.10 127 229 2.7E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 SUPERFAMILY SSF46894 129 222 9.07E-23 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 Pfam PF00072 Response regulator receiver domain 5 113 2.7E-23 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_24545 041e9bccc653e7d9bd3c11e9a5b118a2 230 Gene3D G3DSA:3.40.50.2300 3 126 4.9E-30 T 15-10-2018 C2I28_24775 d69385ca30efa127662699940a62fbed 253 Pfam PF13483 Beta-lactamase superfamily domain 2 212 5.6E-14 T 15-10-2018 C2I28_24775 d69385ca30efa127662699940a62fbed 253 Gene3D G3DSA:3.60.15.10 1 253 1.4E-70 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_24775 d69385ca30efa127662699940a62fbed 253 SUPERFAMILY SSF56281 1 240 7.34E-19 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_19690 3a620792add855271d356eda06b8ab57 562 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 476 492 7.3E-32 T 15-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I28_19690 3a620792add855271d356eda06b8ab57 562 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 387 403 7.3E-32 T 15-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I28_19690 3a620792add855271d356eda06b8ab57 562 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 351 371 7.3E-32 T 15-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I28_19690 3a620792add855271d356eda06b8ab57 562 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 408 419 7.3E-32 T 15-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 C2I28_19690 3a620792add855271d356eda06b8ab57 562 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 253 396 7.1E-54 T 15-10-2018 IPR013856 Peptidase M4 domain GO:0004222 C2I28_19690 3a620792add855271d356eda06b8ab57 562 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 399 561 1.5E-63 T 15-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 C2I28_19690 3a620792add855271d356eda06b8ab57 562 SUPERFAMILY SSF55486 247 561 4.21E-107 T 15-10-2018 C2I28_19690 3a620792add855271d356eda06b8ab57 562 Gene3D G3DSA:1.10.390.10 401 561 6.3E-73 T 15-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily C2I28_19690 3a620792add855271d356eda06b8ab57 562 Gene3D G3DSA:3.10.170.10 251 400 5.3E-66 T 15-10-2018 C2I28_19690 3a620792add855271d356eda06b8ab57 562 Pfam PF03413 Peptidase propeptide and YPEB domain 153 222 5.8E-11 T 15-10-2018 IPR025711 PepSY domain C2I28_19690 3a620792add855271d356eda06b8ab57 562 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 86 137 3.6E-13 T 15-10-2018 IPR011096 FTP domain C2I28_04205 810a3a5693dcbaa72b583457f0c530fa 280 Pfam PF00950 ABC 3 transport family 7 271 4.3E-64 T 15-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 C2I28_04205 810a3a5693dcbaa72b583457f0c530fa 280 Gene3D G3DSA:1.10.3470.10 65 277 2.4E-10 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_04205 810a3a5693dcbaa72b583457f0c530fa 280 SUPERFAMILY SSF81345 4 269 3.14E-36 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 152 164 - T 15-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 PRINTS PR00084 Mannitol dehydrogenase signature 4 14 1.1E-11 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 PRINTS PR00084 Mannitol dehydrogenase signature 152 165 1.1E-11 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 PRINTS PR00084 Mannitol dehydrogenase signature 116 129 1.1E-11 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 PRINTS PR00084 Mannitol dehydrogenase signature 170 185 1.1E-11 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 SUPERFAMILY SSF51735 4 188 2.21E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 SUPERFAMILY SSF48179 201 379 3.2E-42 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 151 368 2.5E-47 T 15-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 3 124 5.8E-23 T 15-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 2 375 37.163 T 15-10-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 Gene3D G3DSA:1.10.1040.10 204 379 1.5E-62 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_09025 d66bb1aae6cfd25f8cf1ae1488d64d1c 380 Gene3D G3DSA:3.40.50.720 2 202 2.7E-65 T 15-10-2018 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 Pfam PF01842 ACT domain 202 254 2.3E-6 T 15-10-2018 IPR002912 ACT domain C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 229 236 - T 15-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 SUPERFAMILY SSF55021 193 281 6.34E-24 T 15-10-2018 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 Gene3D G3DSA:3.40.190.10 8 183 8.0E-53 T 15-10-2018 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 SUPERFAMILY SSF53850 5 186 3.04E-53 T 15-10-2018 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 Pfam PF00800 Prephenate dehydratase 6 186 6.2E-57 T 15-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 Gene3D G3DSA:3.30.70.260 194 283 3.1E-25 T 15-10-2018 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 Gene3D G3DSA:3.40.190.10 86 174 8.0E-53 T 15-10-2018 C2I28_04825 a5e71b2080395df8c3e1b65cabc23919 290 PIRSF PIRSF001500 3 284 2.3E-68 T 15-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 7.5E-24 T 15-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 Gene3D G3DSA:3.30.230.70 1 244 1.3E-62 T 15-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 43.941 T 15-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 SUPERFAMILY SSF54211 1 181 2.28E-44 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 6.0E-117 T 15-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 2.3E-13 T 15-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 15-10-2018 IPR018336 Ribonuclease PH, conserved site C2I28_05070 2fee81ca8ecb18eaf1f6283753a9f959 248 SUPERFAMILY SSF55666 152 236 1.19E-24 T 15-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 C2I28_24995 dc7cdaa6263fcbfb8ccf4572d0200915 145 Pfam PF13560 Helix-turn-helix domain 2 60 2.2E-10 T 15-10-2018 C2I28_24995 dc7cdaa6263fcbfb8ccf4572d0200915 145 SMART SM00530 6 61 2.8E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_24995 dc7cdaa6263fcbfb8ccf4572d0200915 145 SUPERFAMILY SSF47413 2 64 9.92E-15 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_24995 dc7cdaa6263fcbfb8ccf4572d0200915 145 Gene3D G3DSA:1.10.260.40 2 87 2.8E-16 T 15-10-2018 C2I28_03760 93bbdfdae292ad9d1f90547235847d06 330 Gene3D G3DSA:3.40.50.970 2 330 1.5E-114 T 15-10-2018 C2I28_03760 93bbdfdae292ad9d1f90547235847d06 330 SUPERFAMILY SSF52518 8 329 2.0E-99 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_03760 93bbdfdae292ad9d1f90547235847d06 330 Pfam PF00676 Dehydrogenase E1 component 20 320 3.0E-98 T 15-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 Gene3D G3DSA:3.30.250.10 267 342 1.3E-28 T 15-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 SMART SM00382 56 227 4.6E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 SUPERFAMILY SSF52540 2 266 4.87E-66 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 SUPERFAMILY SSF54752 267 325 3.79E-22 T 15-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 ProSitePatterns PS00321 recA signature. 212 220 - T 15-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 Hamap MF_00268 Protein RecA [recA]. 4 328 53.451 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 4.3E-177 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 PRINTS PR00142 RecA protein signature 209 237 3.6E-85 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 PRINTS PR00142 RecA protein signature 242 271 3.6E-85 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 PRINTS PR00142 RecA protein signature 92 121 3.6E-85 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 PRINTS PR00142 RecA protein signature 126 155 3.6E-85 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 PRINTS PR00142 RecA protein signature 296 313 3.6E-85 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 PRINTS PR00142 RecA protein signature 164 193 3.6E-85 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 Gene3D G3DSA:3.40.50.300 25 266 4.0E-82 T 15-10-2018 C2I28_02160 6ac2a6e87fb770aa9d8183a2562dbda8 345 Pfam PF00154 recA bacterial DNA recombination protein 7 267 3.7E-147 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 PIRSF PIRSF005963 1 299 5.6E-139 T 15-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 3 45 2.9E-12 T 15-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 148.706 T 15-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 Gene3D G3DSA:3.20.20.70 14 268 1.4E-23 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 292 9.2E-123 T 15-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 SUPERFAMILY SSF102114 20 287 5.1E-66 T 15-10-2018 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 SMART SM00729 57 265 3.1E-19 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_06480 51e0963ffa9ccd40f576fee6f40e46d1 299 Pfam PF04055 Radical SAM superfamily 63 224 3.5E-15 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_18215 4298b261cddb79a3600b815072176690 443 SMART SM01274 89 222 7.9E-71 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_18215 4298b261cddb79a3600b815072176690 443 PIRSF PIRSF000106 1 441 8.9E-73 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_18215 4298b261cddb79a3600b815072176690 443 Pfam PF00390 Malic enzyme, N-terminal domain 101 222 6.1E-27 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_18215 4298b261cddb79a3600b815072176690 443 Gene3D G3DSA:3.40.50.10380 46 231 1.1E-66 T 15-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I28_18215 4298b261cddb79a3600b815072176690 443 SUPERFAMILY SSF51735 234 437 8.85E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18215 4298b261cddb79a3600b815072176690 443 SUPERFAMILY SSF55021 7 74 2.66E-5 T 15-10-2018 C2I28_18215 4298b261cddb79a3600b815072176690 443 SUPERFAMILY SSF53223 83 232 1.29E-50 T 15-10-2018 C2I28_18215 4298b261cddb79a3600b815072176690 443 Pfam PF13291 ACT domain 8 75 2.6E-6 T 15-10-2018 IPR002912 ACT domain C2I28_18215 4298b261cddb79a3600b815072176690 443 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 250 322 2.5E-7 T 15-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I28_18215 4298b261cddb79a3600b815072176690 443 ProSitePatterns PS00331 Malic enzymes signature. 230 246 - T 15-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I28_18215 4298b261cddb79a3600b815072176690 443 Gene3D G3DSA:3.40.50.720 232 441 8.7E-45 T 15-10-2018 C2I28_18215 4298b261cddb79a3600b815072176690 443 SMART SM00919 234 433 3.9E-49 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 SMART SM00849 506 716 1.5E-11 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 Pfam PF03772 Competence protein 208 466 2.4E-62 T 15-10-2018 IPR004477 ComEC/Rec2-related protein C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 82 745 8.4E-127 T 15-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 Pfam PF13567 Domain of unknown function (DUF4131) 26 164 3.7E-19 T 15-10-2018 IPR025405 Domain of unknown function DUF4131 C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 SUPERFAMILY SSF56281 498 754 3.41E-52 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 Pfam PF00753 Metallo-beta-lactamase superfamily 503 715 2.0E-13 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 Gene3D G3DSA:3.60.15.10 495 760 1.7E-68 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_04430 d853c0f74cc890582571969cadb02fd2 763 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 230 399 1.0E-34 T 15-10-2018 IPR004477 ComEC/Rec2-related protein C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 Pfam PF01546 Peptidase family M20/M25/M40 74 384 9.5E-32 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 Pfam PF07687 Peptidase dimerisation domain 187 279 1.1E-9 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 Gene3D G3DSA:3.40.630.10 16 374 1.2E-146 T 15-10-2018 C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 SUPERFAMILY SSF55031 185 298 6.15E-30 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 Gene3D G3DSA:3.30.70.360 183 297 1.2E-146 T 15-10-2018 C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 SUPERFAMILY SSF53187 5 390 2.3E-88 T 15-10-2018 C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 377 3.5E-125 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_11130 c5b49719a7fd26d7edffd13a6666ff0f 402 PIRSF PIRSF005962 1 393 4.0E-133 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 SMART SM00387 374 486 3.0E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 Gene3D G3DSA:3.30.565.10 330 487 1.0E-36 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 SMART SM00388 259 326 5.2E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 SUPERFAMILY SSF55874 315 484 1.07E-36 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 Gene3D G3DSA:1.10.287.130 254 329 2.8E-16 T 15-10-2018 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 484 7.4E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 324 1.0E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 SMART SM00304 198 251 2.9E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 SUPERFAMILY SSF47384 244 326 5.49E-17 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 PRINTS PR01780 Lantibiotic regulatory protein signature 370 385 1.5E-11 T 15-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 PRINTS PR01780 Lantibiotic regulatory protein signature 268 284 1.5E-11 T 15-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 PRINTS PR01780 Lantibiotic regulatory protein signature 434 449 1.5E-11 T 15-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 PRINTS PR01780 Lantibiotic regulatory protein signature 413 429 1.5E-11 T 15-10-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 Gene3D G3DSA:1.20.1480.50 158 253 3.3E-6 T 15-10-2018 C2I28_25195 254f0817e6300cb6a0ca6c3e0c7f8f94 487 SUPERFAMILY SSF158472 200 248 1.01E-6 T 15-10-2018 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 PIRSF PIRSF004491 4 318 8.9E-105 T 15-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 Pfam PF01687 Riboflavin kinase 186 309 4.6E-36 T 15-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 311 9.6E-95 T 15-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 Gene3D G3DSA:2.40.30.30 190 318 2.1E-41 T 15-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 85 5.0E-9 T 15-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 SMART SM00904 185 311 2.4E-57 T 15-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 SUPERFAMILY SSF52374 20 185 1.58E-29 T 15-10-2018 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 Pfam PF06574 FAD synthetase 16 168 7.6E-49 T 15-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 SUPERFAMILY SSF82114 176 312 2.4E-46 T 15-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 C2I28_02300 00c1849bc80775c8b0ae330ed85a91a5 318 Gene3D G3DSA:3.40.50.620 6 189 1.1E-55 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 Pfam PF13545 Crp-like helix-turn-helix domain 154 221 5.3E-12 T 15-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 Gene3D G3DSA:2.60.120.10 13 155 3.0E-21 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 Pfam PF00027 Cyclic nucleotide-binding domain 36 116 7.3E-15 T 15-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 SUPERFAMILY SSF46785 151 224 6.82E-12 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 SMART SM00100 15 133 2.4E-5 T 15-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 SUPERFAMILY SSF51206 23 138 7.99E-25 T 15-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I28_15755 d87de4c5d6a3c700bb69f5bc0dff5f4a 230 Gene3D G3DSA:1.10.10.10 156 228 9.2E-12 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 PIRSF PIRSF000505 1 429 6.0E-124 T 15-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 Gene3D G3DSA:3.65.10.10 13 424 1.8E-160 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 Gene3D G3DSA:3.65.10.10 23 231 1.8E-160 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 15-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 SUPERFAMILY SSF55205 7 427 1.2E-138 T 15-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 15-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 34.067 T 15-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 427 1.8E-134 T 15-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 C2I28_03155 5b97575fc99c3c37961436cc09c6ac31 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 424 1.2E-126 T 15-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 SMART SM00922 125 230 3.6E-22 T 15-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 15-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 Gene3D G3DSA:3.30.390.10 11 374 2.4E-152 T 15-10-2018 IPR029017 Enolase-like, N-terminal C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 Gene3D G3DSA:3.20.20.120 102 344 2.4E-152 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 SUPERFAMILY SSF51604 95 360 1.17E-80 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 SUPERFAMILY SSF54826 1 112 3.86E-32 T 15-10-2018 C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 15-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 2.7E-27 T 15-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I28_25985 872f741c2f6a35026eaebb051cee02cd 382 Pfam PF13378 Enolase C-terminal domain-like 129 355 4.9E-65 T 15-10-2018 IPR029065 Enolase C-terminal domain-like C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 400 473 4.5E-19 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 Gene3D G3DSA:3.40.50.12780 3 388 1.5E-121 T 15-10-2018 C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 SUPERFAMILY SSF56801 4 482 1.01E-135 T 15-10-2018 C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 Gene3D G3DSA:3.30.300.310 389 485 4.5E-31 T 15-10-2018 C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 31 479 3.3E-149 T 15-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 Pfam PF00501 AMP-binding enzyme 12 391 4.3E-92 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_05990 6b8a547efa8c25d65a7913fffa5a997b 487 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 6 482 46.924 T 15-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 C2I28_02580 f0d5767eb04572a5eb7bc7438dd48dba 293 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 73 288 5.2E-76 T 15-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 C2I28_02580 f0d5767eb04572a5eb7bc7438dd48dba 293 SUPERFAMILY SSF47781 11 63 7.78E-5 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_02580 f0d5767eb04572a5eb7bc7438dd48dba 293 Pfam PF02481 DNA recombination-mediator protein A 74 280 7.0E-78 T 15-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 C2I28_02580 f0d5767eb04572a5eb7bc7438dd48dba 293 SUPERFAMILY SSF102405 82 289 2.29E-32 T 15-10-2018 C2I28_02580 f0d5767eb04572a5eb7bc7438dd48dba 293 Gene3D G3DSA:3.40.50.450 8 292 3.9E-96 T 15-10-2018 C2I28_02405 40b1f7c04e4d95dab4459613b413befa 164 Gene3D G3DSA:3.30.1330.200 4 163 2.9E-47 T 15-10-2018 IPR038592 CheD-like superfamily C2I28_02405 40b1f7c04e4d95dab4459613b413befa 164 SUPERFAMILY SSF64438 7 162 9.15E-45 T 15-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic C2I28_02405 40b1f7c04e4d95dab4459613b413befa 164 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 4 160 25.827 T 15-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 C2I28_02405 40b1f7c04e4d95dab4459613b413befa 164 Pfam PF03975 CheD chemotactic sensory transduction 51 156 5.1E-32 T 15-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 Pfam PF01565 FAD binding domain 35 164 2.4E-24 T 15-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 Gene3D G3DSA:3.90.78.10 217 301 9.8E-35 T 15-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 4.0E-98 T 15-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 Gene3D G3DSA:3.30.465.10 89 216 1.7E-45 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 SUPERFAMILY SSF56194 197 300 5.36E-37 T 15-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 301 92.055 T 15-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 5.8E-29 T 15-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 SUPERFAMILY SSF56176 14 194 1.23E-43 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_02950 d74b8401c70e5a4b8d15dc8bb2b88d33 301 Gene3D G3DSA:3.30.43.10 1 88 1.1E-29 T 15-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 C2I28_15080 1f7ccb9a7845130f9f05f18a37a52c96 64 Pfam PF14178 YppF-like protein 1 58 4.7E-29 T 15-10-2018 IPR025553 YppF-like protein C2I28_15080 1f7ccb9a7845130f9f05f18a37a52c96 64 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 59 4.0E-5 T 15-10-2018 C2I28_23825 6e53bb2fac7f705e96060645e4c7ead1 185 Gene3D G3DSA:3.40.30.10 1 156 1.9E-15 T 15-10-2018 C2I28_23825 6e53bb2fac7f705e96060645e4c7ead1 185 Pfam PF14595 Thioredoxin 12 135 2.1E-36 T 15-10-2018 C2I28_23825 6e53bb2fac7f705e96060645e4c7ead1 185 SUPERFAMILY SSF52833 39 137 4.91E-10 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 SMART SM00470 25 114 1.2E-33 T 15-10-2018 IPR003115 ParB/Sulfiredoxin C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 Gene3D G3DSA:3.90.1530.30 38 100 3.3E-25 T 15-10-2018 C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 24 191 2.0E-62 T 15-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 SUPERFAMILY SSF110849 25 116 3.66E-27 T 15-10-2018 IPR036086 ParB/Sulfiredoxin superfamily C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 Gene3D G3DSA:1.10.10.2830 101 214 1.1E-36 T 15-10-2018 C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 Pfam PF02195 ParB-like nuclease domain 26 113 1.8E-26 T 15-10-2018 IPR003115 ParB/Sulfiredoxin C2I28_07965 dd4021444fd9ebb0bfe5ef9e9c7854d3 289 SUPERFAMILY SSF109709 106 216 3.92E-34 T 15-10-2018 C2I28_13975 535ef49b604e8688e29b0e82d615f731 124 SUPERFAMILY SSF54593 8 123 1.51E-14 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_13975 535ef49b604e8688e29b0e82d615f731 124 Gene3D G3DSA:3.10.180.10 6 123 2.8E-15 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 SUPERFAMILY SSF53244 335 488 4.45E-50 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 486 36.662 T 15-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Gene3D G3DSA:3.40.1190.10 100 339 3.5E-89 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Gene3D G3DSA:3.40.1390.10 5 99 3.1E-29 T 15-10-2018 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 SUPERFAMILY SSF53623 100 333 3.14E-76 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Pfam PF08245 Mur ligase middle domain 109 315 1.1E-57 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 24 486 6.3E-176 T 15-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Gene3D G3DSA:3.90.190.20 340 490 2.9E-62 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Pfam PF01225 Mur ligase family, catalytic domain 26 97 1.6E-14 T 15-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 335 419 2.6E-24 T 15-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I28_02970 3a78c9f4dd3ddf7982c43e90e0d1046d 490 SUPERFAMILY SSF63418 1 100 3.14E-26 T 15-10-2018 IPR035911 MurE/MurF, N-terminal C2I28_07935 afffd8747d4c35bab352f887818740f5 95 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 15-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_07935 afffd8747d4c35bab352f887818740f5 95 Gene3D G3DSA:3.30.70.60 1 95 9.7E-36 T 15-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 C2I28_07935 afffd8747d4c35bab352f887818740f5 95 SUPERFAMILY SSF54995 1 94 6.41E-35 T 15-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07935 afffd8747d4c35bab352f887818740f5 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.3E-32 T 15-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07935 afffd8747d4c35bab352f887818740f5 95 Pfam PF01250 Ribosomal protein S6 3 92 2.0E-30 T 15-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_07935 afffd8747d4c35bab352f887818740f5 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.983 T 15-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 C2I28_20090 ac14a2c4686c6093b1ec6efa8b1f3232 268 Pfam PF12697 Alpha/beta hydrolase family 24 259 3.3E-18 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20090 ac14a2c4686c6093b1ec6efa8b1f3232 268 Gene3D G3DSA:3.40.50.1820 2 266 1.6E-54 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_20090 ac14a2c4686c6093b1ec6efa8b1f3232 268 SUPERFAMILY SSF53474 4 265 6.43E-53 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_20090 ac14a2c4686c6093b1ec6efa8b1f3232 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 5.1E-6 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20090 ac14a2c4686c6093b1ec6efa8b1f3232 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 5.1E-6 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20090 ac14a2c4686c6093b1ec6efa8b1f3232 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 5.1E-6 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 536 5.7E-161 T 15-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 SUPERFAMILY SSF90123 7 491 1.96E-38 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 SMART SM00382 367 552 3.3E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 Pfam PF00664 ABC transporter transmembrane region 22 271 9.8E-10 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 Gene3D G3DSA:3.40.50.300 333 577 3.5E-73 T 15-10-2018 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 Gene3D G3DSA:1.20.1560.10 6 316 7.8E-30 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 SUPERFAMILY SSF52540 339 575 1.25E-69 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07715 5e131d39fc681d76e722a73ef1918026 582 Pfam PF00005 ABC transporter 359 506 4.7E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Gene3D G3DSA:3.10.20.740 5 127 7.8E-30 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Gene3D G3DSA:3.30.70.20 129 212 4.4E-21 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 SMART SM00926 261 315 1.9E-17 T 15-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Gene3D G3DSA:2.20.25.90 261 316 8.1E-19 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 SUPERFAMILY SSF50692 790 936 2.26E-35 T 15-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Pfam PF12838 4Fe-4S dicluster domain 150 208 3.9E-6 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 262 315 4.3E-18 T 15-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Gene3D G3DSA:3.40.228.10 396 595 1.1E-161 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Gene3D G3DSA:2.40.40.20 816 943 1.1E-29 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 SUPERFAMILY SSF54292 6 128 2.61E-30 T 15-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 SUPERFAMILY SSF53706 255 775 8.64E-190 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Pfam PF00384 Molybdopterin oxidoreductase 318 741 1.2E-86 T 15-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 PIRSF PIRSF036643 1 968 0.0 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 6.9E-11 T 15-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 SUPERFAMILY SSF54862 133 218 2.09E-19 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 4.2E-245 T 15-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Gene3D G3DSA:3.40.50.740 323 782 1.1E-161 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 6 78 2.4E-14 T 15-10-2018 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 SMART SM00929 85 126 2.2E-13 T 15-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06765 843fa49c640404851f1676410c7aa37a 979 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 1.9E-22 T 15-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 Gene3D G3DSA:3.40.50.300 7 327 1.1E-102 T 15-10-2018 C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 304 2.0E-18 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 SUPERFAMILY SSF52540 9 259 4.87E-73 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 Pfam PF00005 ABC transporter 37 187 3.1E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 SMART SM00382 45 237 4.8E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_11665 7584adb47ecf48d63d0e5731c5e8561f 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 324 3.2E-30 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_15640 76ecc393864655f9a9eb110585bddc31 306 SUPERFAMILY SSF53807 39 299 7.85E-52 T 15-10-2018 C2I28_15640 76ecc393864655f9a9eb110585bddc31 306 Gene3D G3DSA:3.40.50.1980 49 137 1.4E-26 T 15-10-2018 C2I28_15640 76ecc393864655f9a9eb110585bddc31 306 Pfam PF01497 Periplasmic binding protein 62 280 1.6E-33 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_15640 76ecc393864655f9a9eb110585bddc31 306 Gene3D G3DSA:3.40.50.1980 138 306 8.1E-61 T 15-10-2018 C2I28_15025 7d9c4a5a9ecea545ed1f7b9f1a8db402 162 Gene3D G3DSA:3.10.450.40 96 158 1.9E-27 T 15-10-2018 C2I28_15025 7d9c4a5a9ecea545ed1f7b9f1a8db402 162 Pfam PF03413 Peptidase propeptide and YPEB domain 97 157 3.3E-6 T 15-10-2018 IPR025711 PepSY domain C2I28_15025 7d9c4a5a9ecea545ed1f7b9f1a8db402 162 SUPERFAMILY SSF54403 96 158 8.5E-18 T 15-10-2018 C2I28_15025 7d9c4a5a9ecea545ed1f7b9f1a8db402 162 SUPERFAMILY SSF54403 32 93 1.6E-12 T 15-10-2018 C2I28_15025 7d9c4a5a9ecea545ed1f7b9f1a8db402 162 Gene3D G3DSA:3.10.450.40 24 95 6.3E-22 T 15-10-2018 C2I28_23670 10eec2bee9b4e54d10a7c039d50bc306 39 Pfam PF13215 Protein of unknown function (DUF4023) 1 38 1.6E-20 T 15-10-2018 IPR025097 Protein of unknown function DUF4023 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 Gene3D G3DSA:1.10.287.130 125 199 1.9E-19 T 15-10-2018 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 242 350 2.0E-13 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 Gene3D G3DSA:3.30.565.10 200 355 1.1E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 Gene3D G3DSA:1.20.1480.50 31 124 5.3E-10 T 15-10-2018 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 SMART SM00387 241 351 3.4E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 SUPERFAMILY SSF158472 70 118 4.45E-8 T 15-10-2018 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 SUPERFAMILY SSF47384 114 196 1.55E-18 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 SMART SM00388 129 196 8.1E-17 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 129 195 4.0E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 SMART SM00304 69 121 5.5E-10 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 330 2.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 2.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 306 2.3E-8 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 SUPERFAMILY SSF55874 185 351 3.93E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18775 97516d9e7fe9abb75159e3db3794eab0 358 Pfam PF00672 HAMP domain 69 117 2.6E-9 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_24630 02b5ac1c110b2e9713289f5e16216999 86 Pfam PF02583 Metal-sensitive transcriptional repressor 4 82 9.1E-25 T 15-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 C2I28_24630 02b5ac1c110b2e9713289f5e16216999 86 Gene3D G3DSA:1.20.58.1000 1 85 2.8E-24 T 15-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily C2I28_27305 7fd10b653d3f4192ca6712a859c7ad4d 462 Pfam PF01051 Initiator Replication protein 18 233 3.7E-56 T 15-10-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 C2I28_27305 7fd10b653d3f4192ca6712a859c7ad4d 462 Gene3D G3DSA:1.10.10.10 10 150 5.0E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_27305 7fd10b653d3f4192ca6712a859c7ad4d 462 Gene3D G3DSA:1.10.10.10 151 241 1.2E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_27305 7fd10b653d3f4192ca6712a859c7ad4d 462 SUPERFAMILY SSF46785 23 145 2.9E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_27305 7fd10b653d3f4192ca6712a859c7ad4d 462 SUPERFAMILY SSF46785 136 235 2.63E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_27705 7fd10b653d3f4192ca6712a859c7ad4d 462 Pfam PF01051 Initiator Replication protein 18 233 3.7E-56 T 15-10-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 C2I28_27705 7fd10b653d3f4192ca6712a859c7ad4d 462 Gene3D G3DSA:1.10.10.10 10 150 5.0E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_27705 7fd10b653d3f4192ca6712a859c7ad4d 462 Gene3D G3DSA:1.10.10.10 151 241 1.2E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_27705 7fd10b653d3f4192ca6712a859c7ad4d 462 SUPERFAMILY SSF46785 23 145 2.9E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_27705 7fd10b653d3f4192ca6712a859c7ad4d 462 SUPERFAMILY SSF46785 136 235 2.63E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18435 947d854761c4048d08795019694ef9b0 357 Gene3D G3DSA:3.40.50.300 2 299 6.5E-81 T 15-10-2018 C2I28_18435 947d854761c4048d08795019694ef9b0 357 Pfam PF00005 ABC transporter 18 164 6.9E-36 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_18435 947d854761c4048d08795019694ef9b0 357 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_18435 947d854761c4048d08795019694ef9b0 357 SMART SM00382 27 214 4.1E-19 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_18435 947d854761c4048d08795019694ef9b0 357 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 1.8E-121 T 15-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 C2I28_18435 947d854761c4048d08795019694ef9b0 357 Pfam PF12857 TOBE-like domain 290 345 6.6E-18 T 15-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 C2I28_18435 947d854761c4048d08795019694ef9b0 357 SUPERFAMILY SSF52540 3 246 3.46E-88 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18435 947d854761c4048d08795019694ef9b0 357 SUPERFAMILY SSF50331 239 351 3.61E-12 T 15-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 Gene3D G3DSA:3.40.190.290 93 289 2.1E-32 T 15-10-2018 C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 SUPERFAMILY SSF46785 2 85 1.3E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 SUPERFAMILY SSF53850 94 288 8.15E-27 T 15-10-2018 C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 2.5E-20 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 Gene3D G3DSA:1.10.10.10 1 82 1.3E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_21320 fb7eaf89c20cb69ec983268b33cef14c 289 Pfam PF03466 LysR substrate binding domain 93 288 1.9E-25 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 SUPERFAMILY SSF55594 1 83 3.79E-29 T 15-10-2018 IPR035895 HPr-like superfamily C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 8.0E-27 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 8.0E-27 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 8.0E-27 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 15-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 15-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 Pfam PF00381 PTS HPr component phosphorylation site 3 81 7.6E-31 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 Gene3D G3DSA:3.30.1340.10 1 88 7.6E-39 T 15-10-2018 IPR035895 HPr-like superfamily C2I28_14555 632c617b0209ea37317565c3bfb7c5b9 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 5.1E-34 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 SUPERFAMILY SSF52540 331 573 9.76E-84 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 Gene3D G3DSA:3.40.50.300 327 586 9.7E-80 T 15-10-2018 C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 Pfam PF00664 ABC transporter transmembrane region 19 291 1.2E-42 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 Pfam PF00005 ABC transporter 353 500 1.4E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 SUPERFAMILY SSF90123 5 322 4.32E-72 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 SMART SM00382 362 548 4.7E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 Gene3D G3DSA:1.20.1560.10 3 319 1.1E-77 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_01980 f7ab25f78841d52bffd2cd82f495d10f 587 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 22 528 1.7E-108 T 15-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 Gene3D G3DSA:3.60.20.40 356 536 3.7E-69 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 SUPERFAMILY SSF56235 4 536 1.93E-181 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 355 373 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 410 425 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 379 397 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 235 251 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 283 6.1E-41 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 Pfam PF01019 Gamma-glutamyltranspeptidase 37 531 5.5E-158 T 15-10-2018 C2I28_23160 db308ee94c00974824c53e321e0f734c 536 Gene3D G3DSA:1.10.246.130 251 355 2.8E-24 T 15-10-2018 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 SUPERFAMILY SSF47005 126 170 1.12E-8 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 432 5.3E-176 T 15-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 Pfam PF02817 e3 binding domain 132 165 2.7E-10 T 15-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 15-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 SUPERFAMILY SSF51230 3 94 5.23E-28 T 15-10-2018 IPR011053 Single hybrid motif C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 SUPERFAMILY SSF52777 202 431 6.67E-86 T 15-10-2018 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 Gene3D G3DSA:4.10.320.10 131 171 3.0E-13 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 Gene3D G3DSA:2.40.50.100 1 101 1.4E-27 T 15-10-2018 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 202 431 1.7E-78 T 15-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 Gene3D G3DSA:3.30.559.10 201 432 5.7E-89 T 15-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I28_22650 c718b0254739f852e1c941e73dd346dc 433 Pfam PF00364 Biotin-requiring enzyme 3 75 5.7E-23 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_27170 3dc419935634a9c0057d14c6da177d47 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 1.2E-31 T 15-10-2018 C2I28_27170 3dc419935634a9c0057d14c6da177d47 210 Gene3D G3DSA:1.10.150.240 16 80 1.0E-30 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_27170 3dc419935634a9c0057d14c6da177d47 210 Gene3D G3DSA:3.40.50.1000 5 199 1.0E-30 T 15-10-2018 IPR023214 HAD superfamily C2I28_27170 3dc419935634a9c0057d14c6da177d47 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 169 5.8E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_27170 3dc419935634a9c0057d14c6da177d47 210 SUPERFAMILY SSF56784 1 208 3.2E-34 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_26220 3dc419935634a9c0057d14c6da177d47 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 1.2E-31 T 15-10-2018 C2I28_26220 3dc419935634a9c0057d14c6da177d47 210 Gene3D G3DSA:1.10.150.240 16 80 1.0E-30 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_26220 3dc419935634a9c0057d14c6da177d47 210 Gene3D G3DSA:3.40.50.1000 5 199 1.0E-30 T 15-10-2018 IPR023214 HAD superfamily C2I28_26220 3dc419935634a9c0057d14c6da177d47 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 169 5.8E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_26220 3dc419935634a9c0057d14c6da177d47 210 SUPERFAMILY SSF56784 1 208 3.2E-34 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_27070 3dc419935634a9c0057d14c6da177d47 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 1.2E-31 T 15-10-2018 C2I28_27070 3dc419935634a9c0057d14c6da177d47 210 Gene3D G3DSA:1.10.150.240 16 80 1.0E-30 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_27070 3dc419935634a9c0057d14c6da177d47 210 Gene3D G3DSA:3.40.50.1000 5 199 1.0E-30 T 15-10-2018 IPR023214 HAD superfamily C2I28_27070 3dc419935634a9c0057d14c6da177d47 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 169 5.8E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_27070 3dc419935634a9c0057d14c6da177d47 210 SUPERFAMILY SSF56784 1 208 3.2E-34 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 16 280 2.2E-110 T 15-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 SUPERFAMILY SSF55811 241 360 9.45E-26 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 Gene3D G3DSA:1.10.1670.10 19 222 3.2E-90 T 15-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 Pfam PF00633 Helix-hairpin-helix motif 109 137 5.6E-7 T 15-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 Pfam PF14815 NUDIX domain 244 358 9.6E-25 T 15-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 SMART SM00525 200 220 2.9E-4 T 15-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 Gene3D G3DSA:3.90.79.10 239 362 3.4E-31 T 15-10-2018 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 SMART SM00478 48 199 7.9E-50 T 15-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 177 6.0E-20 T 15-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 SUPERFAMILY SSF48150 13 231 1.16E-74 T 15-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I28_10090 c60cc3b014a08cf1cee1d115cc73ab51 364 Gene3D G3DSA:1.10.340.30 30 141 3.2E-90 T 15-10-2018 C2I28_18460 67cf408afa23a2907ef069d7adcf33dc 235 Pfam PF12730 ABC-2 family transporter protein 5 182 3.4E-18 T 15-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 249 2.0E-49 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 SUPERFAMILY SSF56784 3 254 1.79E-60 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 15-10-2018 C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 1.3E-23 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 Gene3D G3DSA:3.30.1240.10 81 180 3.7E-64 T 15-10-2018 C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 Gene3D G3DSA:3.40.50.1000 4 247 3.7E-64 T 15-10-2018 IPR023214 HAD superfamily C2I28_25150 bf0d77cc35c390a5be20c40e86c60c68 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 2.6E-55 T 15-10-2018 C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 PIRSF PIRSF007510 9 190 1.1E-79 T 15-10-2018 IPR006340 Protein of unknown function DUF436 C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 Hamap MF_00800 UPF0340 protein . 1 190 86.036 T 15-10-2018 IPR006340 Protein of unknown function DUF436 C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 SUPERFAMILY SSF110710 12 188 6.28E-76 T 15-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 22 187 4.0E-64 T 15-10-2018 IPR006340 Protein of unknown function DUF436 C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 16 187 1.7E-77 T 15-10-2018 IPR006340 Protein of unknown function DUF436 C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 Pfam PF04260 Protein of unknown function (DUF436) 17 187 4.2E-77 T 15-10-2018 IPR006340 Protein of unknown function DUF436 C2I28_07380 3589bc19358b83cf9710bf797bba9caa 190 Gene3D G3DSA:3.40.50.10360 11 190 1.4E-79 T 15-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 445 7.8E-154 T 15-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 SUPERFAMILY SSF48013 3 130 3.4E-37 T 15-10-2018 IPR035926 NusB-like superfamily C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 Gene3D G3DSA:3.40.50.150 145 444 8.6E-81 T 15-10-2018 C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 SUPERFAMILY SSF53335 139 445 8.28E-65 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 Pfam PF01189 16S rRNA methyltransferase RsmB/F 246 443 2.0E-59 T 15-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 15-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 Gene3D G3DSA:1.10.940.10 1 144 1.3E-40 T 15-10-2018 IPR035926 NusB-like superfamily C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 Pfam PF01029 NusB family 5 128 2.1E-30 T 15-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 6.5E-27 T 15-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 6.5E-27 T 15-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 6.5E-27 T 15-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 6.5E-27 T 15-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I28_02760 262a62713824e8f8310dea9c6dde5a55 446 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 427 444 6.5E-27 T 15-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Gene3D G3DSA:3.40.50.300 244 421 3.0E-53 T 15-10-2018 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 SUPERFAMILY SSF52540 252 494 1.87E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 337 352 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Pfam PF00158 Sigma-54 interaction domain 253 417 1.1E-51 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Gene3D G3DSA:1.10.10.60 489 553 1.4E-16 T 15-10-2018 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 SMART SM00382 271 414 1.5E-5 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 533 553 3.0E-12 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 516 533 3.0E-12 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Gene3D G3DSA:1.10.8.60 422 488 3.9E-24 T 15-10-2018 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Gene3D G3DSA:3.30.450.20 115 227 2.8E-18 T 15-10-2018 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 SMART SM00091 124 189 4.6E-5 T 15-10-2018 IPR000014 PAS domain C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 SUPERFAMILY SSF55785 124 227 1.27E-12 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 SUPERFAMILY SSF46689 464 553 7.17E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Pfam PF13426 PAS domain 136 227 1.2E-8 T 15-10-2018 IPR000014 PAS domain C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 Pfam PF02954 Bacterial regulatory protein, Fis family 514 550 1.0E-13 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 125 235 3.8E-10 T 15-10-2018 IPR000014 PAS domain C2I28_06990 e388f7b52870df008165b18bcecc28d7 553 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 464 473 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_13520 3e0a31cb0dc905a59bdadb2b35783234 212 PIRSF PIRSF038959 1 212 7.4E-55 T 15-10-2018 IPR026272 Immunity protein SdpI C2I28_13520 3e0a31cb0dc905a59bdadb2b35783234 212 Pfam PF13630 SdpI/YhfL protein family 134 202 3.3E-22 T 15-10-2018 IPR025962 SdpI/YhfL protein family C2I28_13520 3e0a31cb0dc905a59bdadb2b35783234 212 Pfam PF07853 Protein of unknown function (DUF1648) 10 56 2.3E-14 T 15-10-2018 IPR012867 Domain of unknown function DUF1648 C2I28_01430 359070373cbe124ee0d13dfac7979032 148 Gene3D G3DSA:3.40.630.30 1 133 1.0E-24 T 15-10-2018 C2I28_01430 359070373cbe124ee0d13dfac7979032 148 Pfam PF13673 Acetyltransferase (GNAT) domain 27 135 2.1E-14 T 15-10-2018 IPR000182 GNAT domain C2I28_01430 359070373cbe124ee0d13dfac7979032 148 SUPERFAMILY SSF55729 1 135 1.42E-23 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 Gene3D G3DSA:3.60.15.30 11 374 1.1E-136 T 15-10-2018 C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 SUPERFAMILY SSF55718 525 640 6.18E-15 T 15-10-2018 IPR036527 SCP2 sterol-binding domain superfamily C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 Gene3D G3DSA:3.30.1050.10 519 643 2.3E-19 T 15-10-2018 IPR036527 SCP2 sterol-binding domain superfamily C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 Pfam PF00753 Metallo-beta-lactamase superfamily 110 339 1.1E-29 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 Pfam PF14863 Alkyl sulfatase dimerisation 376 512 1.3E-54 T 15-10-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 Gene3D G3DSA:1.25.40.880 375 514 5.1E-57 T 15-10-2018 IPR038536 Alkyl/aryl-sulfatase, dimerisation domain superfamily C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 Pfam PF14864 Alkyl sulfatase C-terminal 522 640 3.8E-24 T 15-10-2018 IPR029229 Alkyl sulfatase, C-terminal C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 SUPERFAMILY SSF56281 12 516 9.38E-131 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_20190 63fc65f45ca31101fc9f9f628ac40327 644 SMART SM00849 114 339 1.3E-16 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_25175 b8a035048111464687ae8e30c3c7ebe2 108 SUPERFAMILY SSF54909 5 103 2.09E-28 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_25175 b8a035048111464687ae8e30c3c7ebe2 108 Gene3D G3DSA:3.30.70.100 10 101 2.6E-37 T 15-10-2018 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 SUPERFAMILY SSF52794 168 265 1.57E-28 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 170 250 1.3E-23 T 15-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 Gene3D G3DSA:3.40.50.2300 164 268 1.1E-33 T 15-10-2018 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 170 260 1.2E-14 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 10 136 3.2E-33 T 15-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 150 6.2E-35 T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 280 622 9.1E-89 T 15-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 SUPERFAMILY SSF55804 1 150 6.67E-32 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 Pfam PF02378 Phosphotransferase system, EIIC 298 566 5.2E-14 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_12755 fc5d5054c5d31b8a945f93ec50ff3852 650 Gene3D G3DSA:3.40.930.10 1 157 4.5E-36 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_05650 7337cea5c1aec98d1516f16e052f7d0b 107 Pfam PF11009 Protein of unknown function (DUF2847) 2 101 4.9E-37 T 15-10-2018 IPR022551 Protein of unknown function DUF2847 C2I28_05650 7337cea5c1aec98d1516f16e052f7d0b 107 Gene3D G3DSA:3.40.30.10 1 105 3.4E-38 T 15-10-2018 C2I28_05650 7337cea5c1aec98d1516f16e052f7d0b 107 SUPERFAMILY SSF52833 2 101 2.87E-9 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_05650 7337cea5c1aec98d1516f16e052f7d0b 107 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 2 102 1.1E-36 T 15-10-2018 IPR022551 Protein of unknown function DUF2847 C2I28_22565 53a12974e03fc80708293e4688e95c86 79 Pfam PF05360 yiaA/B two helix domain 9 61 5.5E-19 T 15-10-2018 IPR008024 YiaAB two helix C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 PIRSF PIRSF026579 1 178 1.6E-94 T 15-10-2018 IPR014213 Sporulation stage V, protein T C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 7.9E-45 T 15-10-2018 IPR039472 Sporulation stage V protein T, GAF domain C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 SMART SM00966 8 52 1.1E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 15-10-2018 C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 9.7E-90 T 15-10-2018 IPR014213 Sporulation stage V, protein T C2I28_08385 c073f0e8184d1e4077d8679b10ccc8c8 178 Gene3D G3DSA:3.30.450.40 56 178 1.6E-45 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_01310 4c418c174756eccb5c7f47680dac5c3c 299 SUPERFAMILY SSF103481 37 137 3.14E-13 T 15-10-2018 C2I28_01310 4c418c174756eccb5c7f47680dac5c3c 299 Pfam PF00892 EamA-like transporter family 149 280 1.5E-21 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_01310 4c418c174756eccb5c7f47680dac5c3c 299 Pfam PF00892 EamA-like transporter family 9 136 5.5E-17 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_01310 4c418c174756eccb5c7f47680dac5c3c 299 SUPERFAMILY SSF103481 183 283 2.09E-13 T 15-10-2018 C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 SUPERFAMILY SSF46785 954 1020 1.15E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 SUPERFAMILY SSF52540 639 930 6.37E-49 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 Pfam PF09397 Ftsk gamma domain 956 1017 5.4E-29 T 15-10-2018 IPR018541 FtsK gamma domain C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 Pfam PF01580 FtsK/SpoIIIE family 665 857 6.4E-66 T 15-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 Gene3D G3DSA:1.10.10.10 946 1015 1.2E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 Gene3D G3DSA:3.40.50.300 662 941 1.9E-114 T 15-10-2018 C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 SMART SM00843 954 1019 1.8E-37 T 15-10-2018 IPR018541 FtsK gamma domain C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 SMART SM00382 700 878 2.7E-5 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_05680 c5060244f27150953cf531dc0fa46b23 1033 Gene3D G3DSA:3.30.980.40 558 661 6.3E-36 T 15-10-2018 C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 SUPERFAMILY SSF46785 9 141 8.94E-32 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 Gene3D G3DSA:1.10.10.10 2 140 3.9E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 3.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 3.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 3.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 3.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 Pfam PF01047 MarR family 32 89 1.7E-15 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20750 cf73d94181de95cc63fd09a1564fada3 150 SMART SM00347 25 125 1.5E-24 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21035 e4510ffff588666f1ff4ad141e6cde47 252 Pfam PF11495 Archaeal transcriptional regulator TrmB 102 222 9.7E-11 T 15-10-2018 IPR021586 Transcription regulator TrmB, C-terminal C2I28_21035 e4510ffff588666f1ff4ad141e6cde47 252 SUPERFAMILY SSF46785 1 70 4.2E-8 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21035 e4510ffff588666f1ff4ad141e6cde47 252 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 69 1.9E-19 T 15-10-2018 IPR002831 Transcription regulator TrmB, N-terminal C2I28_21035 e4510ffff588666f1ff4ad141e6cde47 252 Gene3D G3DSA:1.10.10.10 1 95 2.3E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 89 3.6E-20 T 15-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SMART SM00567 E-Z type HEAT repeats 248 277 1.4 T 15-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SMART SM00567 E-Z type HEAT repeats 219 246 690.0 T 15-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SMART SM00567 E-Z type HEAT repeats 279 308 24.0 T 15-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SMART SM00567 E-Z type HEAT repeats 310 339 2.4E-4 T 15-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 Gene3D G3DSA:1.25.10.10 192 372 7.7E-26 T 15-10-2018 IPR011989 Armadillo-like helical C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SMART SM00932 4 90 2.3E-30 T 15-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SUPERFAMILY SSF110836 2 90 2.48E-24 T 15-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 SUPERFAMILY SSF48371 201 372 1.2E-32 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 Pfam PF13646 HEAT repeats 267 343 2.8E-12 T 15-10-2018 C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 Pfam PF13769 Virulence factor 108 188 1.6E-32 T 15-10-2018 IPR025989 Virulence factor domain C2I28_17755 a89a7aa5890f74bc333204a19abc0e61 374 Gene3D G3DSA:3.30.1370.70 1 94 3.1E-29 T 15-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 Pfam PF01872 RibD C-terminal domain 148 354 9.0E-53 T 15-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 SUPERFAMILY SSF53927 4 143 2.09E-45 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 SUPERFAMILY SSF53597 145 360 6.71E-59 T 15-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 357 9.2E-66 T 15-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 100 2.1E-20 T 15-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 Gene3D G3DSA:3.40.140.10 2 136 3.2E-44 T 15-10-2018 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 PIRSF PIRSF006769 2 361 4.4E-131 T 15-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 4.0E-120 T 15-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 15-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I28_17635 8ce3f3946565cf5fc2e1a213d5589bd2 363 Gene3D G3DSA:3.40.430.10 137 362 5.8E-73 T 15-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I28_27375 94bd401be722eabdc0e03dc943115f57 434 SUPERFAMILY SSF53756 52 429 2.3E-84 T 15-10-2018 C2I28_27375 94bd401be722eabdc0e03dc943115f57 434 Gene3D G3DSA:3.40.50.2000 240 414 3.7E-81 T 15-10-2018 C2I28_27375 94bd401be722eabdc0e03dc943115f57 434 Gene3D G3DSA:3.40.50.2000 63 423 3.7E-81 T 15-10-2018 C2I28_27375 94bd401be722eabdc0e03dc943115f57 434 Pfam PF00534 Glycosyl transferases group 1 246 408 2.3E-42 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_27375 94bd401be722eabdc0e03dc943115f57 434 Pfam PF13439 Glycosyltransferase Family 4 63 241 4.6E-19 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 Gene3D G3DSA:1.10.10.60 220 273 4.8E-18 T 15-10-2018 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 Gene3D G3DSA:1.10.10.60 171 219 3.1E-12 T 15-10-2018 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 254 2.4E-5 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 270 2.4E-5 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 SUPERFAMILY SSF46689 222 271 3.94E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 SUPERFAMILY SSF51215 4 153 1.1E-23 T 15-10-2018 IPR037923 Transcription regulator HTH-like C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 Gene3D G3DSA:2.60.120.280 20 155 4.0E-12 T 15-10-2018 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 Pfam PF12833 Helix-turn-helix domain 192 271 9.1E-21 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 SMART SM00342 186 270 2.0E-30 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 223 266 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 SUPERFAMILY SSF46689 170 220 3.05E-5 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_18685 c6f3aa84aa8bf960ed10aee1ec6b5840 275 Pfam PF02311 AraC-like ligand binding domain 24 149 8.6E-24 T 15-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 C2I28_20915 28fdd4933f7a2ae375b113a1553bd247 146 Gene3D G3DSA:2.60.40.790 15 137 5.4E-19 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_20915 28fdd4933f7a2ae375b113a1553bd247 146 SUPERFAMILY SSF49764 21 139 2.55E-16 T 15-10-2018 IPR008978 HSP20-like chaperone C2I28_20915 28fdd4933f7a2ae375b113a1553bd247 146 Pfam PF00011 Hsp20/alpha crystallin family 41 143 5.1E-9 T 15-10-2018 IPR002068 Alpha crystallin/Hsp20 domain C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 Gene3D G3DSA:3.40.50.2300 2 138 1.6E-31 T 15-10-2018 C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 Pfam PF00072 Response regulator receiver domain 6 111 6.0E-24 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 SUPERFAMILY SSF52172 2 111 7.83E-29 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 SMART SM00448 4 127 1.7E-25 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 SUPERFAMILY SSF52738 158 346 1.96E-57 T 15-10-2018 IPR035909 Methylesterase CheB, C-terminal C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 346 37.464 T 15-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 Pfam PF01339 CheB methylesterase 161 340 3.6E-52 T 15-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 PIRSF PIRSF000876 1 347 5.1E-125 T 15-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 C2I28_02420 7e64dcefdc2c83d6a21b09d50114bcd7 347 Gene3D G3DSA:3.40.50.180 154 344 9.2E-64 T 15-10-2018 IPR035909 Methylesterase CheB, C-terminal C2I28_25135 5d26068a00219d137ddf96ad02c87924 135 SUPERFAMILY SSF109915 2 82 2.62E-7 T 15-10-2018 IPR035945 YhaI-like superfamily C2I28_25135 5d26068a00219d137ddf96ad02c87924 135 Gene3D G3DSA:1.10.3750.10 2 131 1.4E-7 T 15-10-2018 IPR035945 YhaI-like superfamily C2I28_25135 5d26068a00219d137ddf96ad02c87924 135 Pfam PF08963 Protein of unknown function (DUF1878) 4 81 9.4E-7 T 15-10-2018 IPR015058 Protein of unknown function DUF1878 C2I28_18405 3d95bb27474d534474e7424112c57391 459 SMART SM00304 177 229 2.4E-10 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_18405 3d95bb27474d534474e7424112c57391 459 SMART SM00388 230 296 1.7E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18405 3d95bb27474d534474e7424112c57391 459 SUPERFAMILY SSF158472 178 226 4.84E-10 T 15-10-2018 C2I28_18405 3d95bb27474d534474e7424112c57391 459 SUPERFAMILY SSF47384 213 296 1.79E-17 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_18405 3d95bb27474d534474e7424112c57391 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 295 2.1E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18405 3d95bb27474d534474e7424112c57391 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 448 5.5E-26 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18405 3d95bb27474d534474e7424112c57391 459 Pfam PF00672 HAMP domain 179 225 2.1E-9 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_18405 3d95bb27474d534474e7424112c57391 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 6.1E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18405 3d95bb27474d534474e7424112c57391 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 6.1E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18405 3d95bb27474d534474e7424112c57391 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 6.1E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18405 3d95bb27474d534474e7424112c57391 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 6.1E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_18405 3d95bb27474d534474e7424112c57391 459 SMART SM00387 340 450 2.9E-37 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18405 3d95bb27474d534474e7424112c57391 459 SUPERFAMILY SSF55874 286 448 7.33E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18405 3d95bb27474d534474e7424112c57391 459 Gene3D G3DSA:1.10.287.130 226 292 2.9E-19 T 15-10-2018 C2I28_18405 3d95bb27474d534474e7424112c57391 459 Gene3D G3DSA:3.30.565.10 293 448 1.6E-45 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18405 3d95bb27474d534474e7424112c57391 459 Gene3D G3DSA:1.10.8.500 176 225 6.0E-10 T 15-10-2018 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 SUPERFAMILY SSF52518 4 173 2.94E-47 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 319 8.7E-36 T 15-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 SUPERFAMILY SSF52518 358 553 3.14E-60 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 15-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 Gene3D G3DSA:3.40.50.970 348 564 1.1E-60 T 15-10-2018 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 SUPERFAMILY SSF52467 187 351 2.99E-48 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.4E-46 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 Gene3D G3DSA:3.40.50.1220 183 335 1.6E-50 T 15-10-2018 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 1.8E-39 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_21645 ec3fc5c444b44a3b665e1441575333c1 566 Gene3D G3DSA:3.40.50.970 2 182 3.1E-60 T 15-10-2018 C2I28_27700 5621e1d4cc620c8dd55b2a139151792d 310 Pfam PF00589 Phage integrase family 142 295 6.0E-8 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_27700 5621e1d4cc620c8dd55b2a139151792d 310 Gene3D G3DSA:1.10.150.130 5 95 1.1E-11 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_27700 5621e1d4cc620c8dd55b2a139151792d 310 Gene3D G3DSA:1.10.443.10 101 309 2.3E-12 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_27700 5621e1d4cc620c8dd55b2a139151792d 310 SUPERFAMILY SSF47823 14 94 4.51E-5 T 15-10-2018 C2I28_27700 5621e1d4cc620c8dd55b2a139151792d 310 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 87 5.6E-5 T 15-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I28_27700 5621e1d4cc620c8dd55b2a139151792d 310 SUPERFAMILY SSF56349 112 301 2.74E-15 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_27300 5621e1d4cc620c8dd55b2a139151792d 310 Pfam PF00589 Phage integrase family 142 295 6.0E-8 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_27300 5621e1d4cc620c8dd55b2a139151792d 310 Gene3D G3DSA:1.10.150.130 5 95 1.1E-11 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_27300 5621e1d4cc620c8dd55b2a139151792d 310 Gene3D G3DSA:1.10.443.10 101 309 2.3E-12 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_27300 5621e1d4cc620c8dd55b2a139151792d 310 SUPERFAMILY SSF47823 14 94 4.51E-5 T 15-10-2018 C2I28_27300 5621e1d4cc620c8dd55b2a139151792d 310 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 87 5.6E-5 T 15-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I28_27300 5621e1d4cc620c8dd55b2a139151792d 310 SUPERFAMILY SSF56349 112 301 2.74E-15 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 31 505 1.6E-188 T 15-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 Pfam PF13396 Phospholipase_D-nuclease N-terminal 43 81 2.3E-6 T 15-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 Pfam PF13091 PLD-like domain 348 467 1.0E-27 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 Pfam PF13091 PLD-like domain 155 298 2.6E-11 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 SMART SM00155 418 445 4.0E-8 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 SMART SM00155 238 265 8.5E-6 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 Hamap MF_01916 Cardiolipin synthase. 33 505 43.561 T 15-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 SUPERFAMILY SSF56024 123 336 1.92E-52 T 15-10-2018 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 SUPERFAMILY SSF56024 290 490 1.7E-47 T 15-10-2018 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 Gene3D G3DSA:3.30.870.10 136 317 6.2E-47 T 15-10-2018 C2I28_11770 f2c4f242552f319ad2da5e84eaed298b 505 Gene3D G3DSA:3.30.870.10 320 504 3.7E-32 T 15-10-2018 C2I28_00865 79bbacb5fa268fde789a137775b23bda 411 Pfam PF05977 Transmembrane secretion effector 7 406 1.4E-28 T 15-10-2018 IPR010290 Transmembrane secretion effector C2I28_00865 79bbacb5fa268fde789a137775b23bda 411 SUPERFAMILY SSF103473 14 405 7.32E-43 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_00865 79bbacb5fa268fde789a137775b23bda 411 Gene3D G3DSA:1.20.1250.20 8 400 1.3E-38 T 15-10-2018 C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 SUPERFAMILY SSF50249 4 65 3.31E-16 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 21 449 1.7E-188 T 15-10-2018 C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 94 454 5.3E-19 T 15-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 Gene3D G3DSA:3.40.1350.30 133 288 1.1E-128 T 15-10-2018 C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 Gene3D G3DSA:2.40.50.140 2 84 1.1E-21 T 15-10-2018 C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 439 449 - T 15-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 SUPERFAMILY SSF53335 73 454 4.11E-94 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 Gene3D G3DSA:3.40.50.150 86 451 1.1E-128 T 15-10-2018 C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 387 418 - T 15-10-2018 IPR030390 RNA methyltransferase TrmA, active site C2I28_09550 55be50e6f3bab3f72cac9c720e8694bb 457 Pfam PF01938 TRAM domain 9 64 5.5E-11 T 15-10-2018 IPR002792 TRAM domain C2I28_21070 5e63cf0d0585fb37ee957ba9518f5001 276 Pfam PF03631 Virulence factor BrkB 16 258 1.5E-58 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_21070 5e63cf0d0585fb37ee957ba9518f5001 276 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 6 258 1.3E-44 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_21070 5e63cf0d0585fb37ee957ba9518f5001 276 PIRSF PIRSF035875 2 267 2.1E-64 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_21740 1b2f805bb9647b458f419196ae109900 235 Gene3D G3DSA:3.40.50.880 21 221 6.5E-42 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_21740 1b2f805bb9647b458f419196ae109900 235 Pfam PF03575 Peptidase family S51 4 199 2.8E-58 T 15-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 C2I28_21740 1b2f805bb9647b458f419196ae109900 235 SUPERFAMILY SSF52317 19 197 4.87E-31 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_22905 5d92d733c3ec04f472579da109e41f1e 368 Pfam PF00535 Glycosyl transferase family 2 40 165 2.0E-20 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_22905 5d92d733c3ec04f472579da109e41f1e 368 Gene3D G3DSA:3.90.550.10 17 259 1.5E-30 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_22905 5d92d733c3ec04f472579da109e41f1e 368 SUPERFAMILY SSF53448 34 321 1.41E-34 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 SMART SM00387 370 482 2.2E-35 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 SUPERFAMILY SSF55874 319 481 7.99E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 Gene3D G3DSA:1.10.287.130 205 328 3.3E-27 T 15-10-2018 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 SMART SM00388 261 328 2.3E-20 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 327 8.8E-19 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 Gene3D G3DSA:3.30.565.10 355 482 2.0E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 6.8E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 6.8E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 6.8E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 6.8E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 482 2.3E-25 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07810 767cdb73fbfb41d450590e5e73d67d97 482 SUPERFAMILY SSF47384 245 326 8.44E-19 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 Gene3D G3DSA:3.40.50.620 230 387 4.9E-22 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 SUPERFAMILY SSF56235 44 219 1.54E-28 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 SUPERFAMILY SSF52402 237 569 3.39E-25 T 15-10-2018 C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 Gene3D G3DSA:3.40.50.620 429 615 1.4E-9 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 PIRSF PIRSF001589 432 602 1.3E-5 T 15-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 PIRSF PIRSF001589 1 386 3.7E-43 T 15-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 Gene3D G3DSA:3.60.20.10 2 226 1.0E-31 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 Pfam PF00733 Asparagine synthase 245 575 2.5E-21 T 15-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 C2I28_18950 d7d26b52647699480d4c85383b1184bd 646 Pfam PF13537 Glutamine amidotransferase domain 55 166 1.9E-20 T 15-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 SUPERFAMILY SSF51569 1 220 1.15E-72 T 15-10-2018 C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 219 3.1E-55 T 15-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 Gene3D G3DSA:3.20.20.70 1 222 1.7E-83 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 Hamap MF_00494 Probable transaldolase [tal]. 1 221 43.824 T 15-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 6.8E-81 T 15-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_19700 a82b3f71d7eac854592a88aafdf31fce 222 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 Gene3D G3DSA:3.40.50.2300 63 307 2.1E-65 T 15-10-2018 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 Gene3D G3DSA:3.40.50.2300 157 286 2.1E-65 T 15-10-2018 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.1E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.1E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 Gene3D G3DSA:1.10.260.40 1 59 1.4E-23 T 15-10-2018 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 SUPERFAMILY SSF47413 2 61 1.65E-19 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 SUPERFAMILY SSF53822 59 321 2.75E-64 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 SMART SM00354 2 72 2.7E-32 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.7E-20 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 Pfam PF13377 Periplasmic binding protein-like domain 166 327 3.7E-24 T 15-10-2018 C2I28_15880 f55ee2f5fabd28a0de5de0b6e2f2bc79 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 15-10-2018 C2I28_23370 35d56f08e0b604fe1c2f4718d9b2e2d8 148 Pfam PF00583 Acetyltransferase (GNAT) family 36 135 3.0E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_23370 35d56f08e0b604fe1c2f4718d9b2e2d8 148 Gene3D G3DSA:3.40.630.30 3 141 2.9E-25 T 15-10-2018 C2I28_23370 35d56f08e0b604fe1c2f4718d9b2e2d8 148 SUPERFAMILY SSF55729 1 138 1.2E-23 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_13710 2aebe64d9eac99164b3e83e10d0e3345 148 SUPERFAMILY SSF54197 2 106 1.14E-18 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_13710 2aebe64d9eac99164b3e83e10d0e3345 148 Gene3D G3DSA:3.30.428.10 1 145 3.4E-19 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_13710 2aebe64d9eac99164b3e83e10d0e3345 148 Pfam PF01230 HIT domain 19 102 8.5E-6 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_09160 88a67691f0eb7771c1e0046db2cfb4b3 118 Pfam PF01740 STAS domain 12 94 2.1E-11 T 15-10-2018 IPR002645 STAS domain C2I28_09160 88a67691f0eb7771c1e0046db2cfb4b3 118 SUPERFAMILY SSF52091 3 111 9.22E-19 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09160 88a67691f0eb7771c1e0046db2cfb4b3 118 Gene3D G3DSA:3.30.750.24 1 116 4.3E-32 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_00945 b9907365a09f80d10203761213dd8649 86 Pfam PF02583 Metal-sensitive transcriptional repressor 4 82 3.6E-26 T 15-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 C2I28_00945 b9907365a09f80d10203761213dd8649 86 Gene3D G3DSA:1.20.58.1000 1 83 5.1E-25 T 15-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily C2I28_22825 a52506371261b94778f2d5a8a047cc09 352 SUPERFAMILY SSF81345 7 343 5.62E-78 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_22825 a52506371261b94778f2d5a8a047cc09 352 Pfam PF01032 FecCD transport family 24 343 3.9E-92 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_22825 a52506371261b94778f2d5a8a047cc09 352 Gene3D G3DSA:1.10.3470.10 9 350 2.7E-100 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Gene3D G3DSA:3.90.226.10 199 372 1.4E-93 T 15-10-2018 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 SUPERFAMILY SSF52096 49 379 9.44E-71 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Gene3D G3DSA:1.10.101.10 385 466 1.9E-15 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Pfam PF03572 Peptidase family S41 212 374 2.2E-48 T 15-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Pfam PF13180 PDZ domain 112 191 4.5E-17 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 SMART SM00228 111 182 3.3E-17 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 SUPERFAMILY SSF50156 82 204 5.53E-23 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Gene3D G3DSA:3.30.750.44 58 350 1.4E-93 T 15-10-2018 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Pfam PF01471 Putative peptidoglycan binding domain 398 453 4.8E-14 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 SUPERFAMILY SSF47090 385 456 2.22E-16 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 SMART SM00245 184 375 1.5E-67 T 15-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 Gene3D G3DSA:2.30.42.10 111 198 1.4E-93 T 15-10-2018 C2I28_07010 27bfee4a5881146463405ae1098beaf4 479 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 64 386 5.5E-120 T 15-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 15-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 Gene3D G3DSA:1.10.286.10 1 54 3.4E-25 T 15-10-2018 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 7.8E-81 T 15-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 15-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 Pfam PF01227 GTP cyclohydrolase I 9 186 3.0E-80 T 15-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 Gene3D G3DSA:3.30.1130.10 55 188 3.2E-60 T 15-10-2018 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.564 T 15-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 C2I28_03235 d61c39918e9f053d10a2ecec7cc0b146 188 SUPERFAMILY SSF55620 4 187 1.48E-78 T 15-10-2018 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 Pfam PF11762 L-arabinose isomerase C-terminal domain 360 473 3.3E-43 T 15-10-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 6 303 7.0E-163 T 15-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 SUPERFAMILY SSF50443 327 474 1.41E-57 T 15-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 Pfam PF02610 L-arabinose isomerase 6 357 1.6E-169 T 15-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 Hamap MF_00519 L-arabinose isomerase [araA]. 1 474 61.064 T 15-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 SUPERFAMILY SSF53743 1 327 2.46E-123 T 15-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 PIRSF PIRSF001478 1 474 7.4E-239 T 15-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 C2I28_25570 aee39d3f11c2f5c7bcd93b5763fd9064 474 Gene3D G3DSA:3.40.50.10940 1 175 5.7E-86 T 15-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 PIRSF PIRSF036492 26 477 2.6E-84 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 Gene3D G3DSA:3.40.605.10 19 471 3.1E-158 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 Gene3D G3DSA:3.40.309.10 251 442 3.1E-158 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 Pfam PF00171 Aldehyde dehydrogenase family 14 473 1.4E-152 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 SUPERFAMILY SSF53720 3 476 9.42E-146 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_19285 d098aa7d31f89027eeb314f2ac951912 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 2.9E-21 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 2.9E-21 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 2.9E-21 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 Pfam PF00717 Peptidase S24-like 35 102 5.9E-20 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 SUPERFAMILY SSF51306 26 181 3.56E-53 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 Gene3D G3DSA:2.10.109.10 58 183 8.1E-48 T 15-10-2018 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 1.8E-56 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_02605 2365aabebe2e6aa8a426dcafda6a2872 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 15-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I28_18000 95f6e580ff64b56c73fb8518c5b01937 497 Gene3D G3DSA:3.40.605.10 27 490 5.3E-207 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_18000 95f6e580ff64b56c73fb8518c5b01937 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_18000 95f6e580ff64b56c73fb8518c5b01937 497 Gene3D G3DSA:3.40.309.10 273 462 5.3E-207 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_18000 95f6e580ff64b56c73fb8518c5b01937 497 SUPERFAMILY SSF53720 22 495 2.62E-188 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_18000 95f6e580ff64b56c73fb8518c5b01937 497 Pfam PF00171 Aldehyde dehydrogenase family 31 492 6.4E-194 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 275 294 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 93 111 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 198 220 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 312 328 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 115 136 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 331 342 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 72 86 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 343 366 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00750 Beta-amylase (glycosyl hydrolase family 14) signature 379 401 5.8E-56 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 Pfam PF01373 Glycosyl hydrolase family 14 44 439 1.6E-198 T 15-10-2018 IPR001554 Glycoside hydrolase, family 14 GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 Gene3D G3DSA:3.20.20.80 31 446 5.2E-158 T 15-10-2018 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 ProSitePatterns PS00506 Beta-amylase active site 1. 119 127 - T 15-10-2018 IPR018238 Glycoside hydrolase, family 14, conserved site GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 SMART SM01065 449 545 2.3E-12 T 15-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 SUPERFAMILY SSF51445 37 502 7.16E-138 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 Pfam PF00686 Starch binding domain 454 541 2.6E-16 T 15-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 ProSitePatterns PS00679 Beta-amylase active site 2. 198 208 - T 15-10-2018 IPR018238 Glycoside hydrolase, family 14, conserved site GO:0000272|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00841 Bacterial beta-amylase signature 251 268 3.1E-24 T 15-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00841 Bacterial beta-amylase signature 138 157 3.1E-24 T 15-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00841 Bacterial beta-amylase signature 235 250 3.1E-24 T 15-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 PRINTS PR00841 Bacterial beta-amylase signature 416 437 3.1E-24 T 15-10-2018 IPR000125 Glycoside hydrolase, family 14A, bacterial GO:0005976|GO:0016161 KEGG: 00500+3.2.1.2|MetaCyc: PWY-6724|MetaCyc: PWY-842 C2I28_09855 6a52c0e12d00d855d72f7a0a004898a5 545 Gene3D G3DSA:2.60.40.10 447 545 4.9E-28 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Gene3D G3DSA:3.20.20.70 1 207 2.1E-51 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Gene3D G3DSA:3.40.50.1100 265 595 2.5E-186 T 15-10-2018 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 218 600 4.4E-190 T 15-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 SUPERFAMILY SSF51366 1 206 1.43E-44 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 263 589 4.6E-47 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 202 6.5E-45 T 15-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Gene3D G3DSA:3.40.50.1100 221 417 2.5E-186 T 15-10-2018 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 292 306 - T 15-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 SUPERFAMILY SSF53686 214 600 1.15E-145 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 213 602 52.679 T 15-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 C2I28_03175 f4a6a9c3cf2398a51ca8b01bd463274a 612 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 209 33.395 T 15-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.6E-30 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 SMART SM00357 3 66 4.3E-31 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 SUPERFAMILY SSF50249 1 64 1.71E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 PRINTS PR00050 Cold shock protein signature 39 57 1.3E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 PRINTS PR00050 Cold shock protein signature 24 33 1.3E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 Gene3D G3DSA:2.40.50.140 1 66 1.1E-30 T 15-10-2018 C2I28_25915 67fcc76e9edce4ac486517bc5a093ed3 66 PIRSF PIRSF002599 1 66 9.0E-25 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 SUPERFAMILY SSF51735 3 154 4.45E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 Gene3D G3DSA:3.40.50.720 5 263 1.7E-76 T 15-10-2018 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 3.1E-90 T 15-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 SUPERFAMILY SSF55347 129 237 1.33E-36 T 15-10-2018 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 128 1.3E-33 T 15-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 15-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 264 5.6E-32 T 15-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 Gene3D G3DSA:3.30.360.10 130 235 1.7E-76 T 15-10-2018 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 PIRSF PIRSF000161 2 266 4.0E-70 T 15-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_14965 2652c5c4259be8b92e84d825922e870d 266 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 266 30.642 T 15-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 SUPERFAMILY SSF51735 3 253 4.51E-74 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 5.8E-61 T 15-10-2018 C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.6E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-35 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.5E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24980 e526773b42bf54ed7c2e8c60d3ae7160 260 Gene3D G3DSA:3.40.50.720 1 257 3.6E-75 T 15-10-2018 C2I28_21920 3031e2c25f94202f8b5f20148825fd1e 117 ProDom PD338809 BH2346 YXIB BH4015 BH0976 PREFOLDIN 21 106 2.0E-8 T 15-10-2018 C2I28_21920 3031e2c25f94202f8b5f20148825fd1e 117 Pfam PF16888 Domain of unknown function (DUF5082) 7 110 8.2E-13 T 15-10-2018 IPR031681 Protein of unknown function DUF5082 C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 2.6E-14 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 Gene3D G3DSA:1.10.357.10 60 204 2.6E-15 T 15-10-2018 C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 SUPERFAMILY SSF48498 92 201 2.89E-7 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 4.3E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 4.3E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 SUPERFAMILY SSF46689 18 90 1.2E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_07480 ddccc0df94757d7b95a52ffc16fcace4 214 Gene3D G3DSA:1.10.10.60 16 59 5.6E-17 T 15-10-2018 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 485 5.1E-178 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 3.7E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 3.7E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 3.7E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 3.7E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 3.7E-44 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 Gene3D G3DSA:3.30.360.10 178 487 1.0E-115 T 15-10-2018 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 Gene3D G3DSA:3.40.50.720 2 177 5.1E-60 T 15-10-2018 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 484 8.0E-105 T 15-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 SUPERFAMILY SSF55347 179 487 1.99E-104 T 15-10-2018 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 189 1.9E-63 T 15-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 SUPERFAMILY SSF51735 2 185 4.13E-62 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 3 486 79.219 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_24255 086cce55293903cd2ebd617ac4d56028 500 PIRSF PIRSF000110 1 488 8.2E-184 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_13875 a73d6860b15f8a8c1507d273ccc00f8b 325 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 34 58 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_13875 a73d6860b15f8a8c1507d273ccc00f8b 325 Pfam PF00294 pfkB family carbohydrate kinase 1 312 1.0E-79 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_13875 a73d6860b15f8a8c1507d273ccc00f8b 325 Gene3D G3DSA:3.40.1190.20 2 324 1.8E-103 T 15-10-2018 IPR029056 Ribokinase-like C2I28_13875 a73d6860b15f8a8c1507d273ccc00f8b 325 SUPERFAMILY SSF53613 1 318 2.96E-87 T 15-10-2018 IPR029056 Ribokinase-like C2I28_13875 a73d6860b15f8a8c1507d273ccc00f8b 325 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 SUPERFAMILY SSF52141 3 221 3.27E-95 T 15-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 5 220 41.086 T 15-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 213 2.4E-86 T 15-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 Pfam PF03167 Uracil DNA glycosylase superfamily 52 208 2.3E-27 T 15-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 SMART SM00986 49 209 8.0E-38 T 15-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 15-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 SMART SM00987 49 209 8.0E-38 T 15-10-2018 C2I28_07615 69b54e790c6c634c26826b639f5e3558 224 Gene3D G3DSA:3.40.470.10 1 224 1.4E-100 T 15-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_10135 8e948ca0672b7fc4535c60eb069bfe34 337 Gene3D G3DSA:3.40.50.300 8 278 5.9E-61 T 15-10-2018 C2I28_10135 8e948ca0672b7fc4535c60eb069bfe34 337 Pfam PF00005 ABC transporter 42 185 4.4E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_10135 8e948ca0672b7fc4535c60eb069bfe34 337 SMART SM00382 50 234 2.2E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_10135 8e948ca0672b7fc4535c60eb069bfe34 337 SUPERFAMILY SSF52540 36 252 5.62E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 SUPERFAMILY SSF56719 31 488 3.14E-183 T 15-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Gene3D G3DSA:3.30.1360.40 237 333 9.4E-220 T 15-10-2018 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 SMART SM00434 12 465 3.2E-299 T 15-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Gene3D G3DSA:1.10.268.10 370 459 9.4E-220 T 15-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 1.2E-161 T 15-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 SUPERFAMILY SSF101904 500 819 2.75E-113 T 15-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 6 808 25.108 T 15-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Gene3D G3DSA:3.90.199.10 33 486 9.4E-220 T 15-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 599 5.9E-12 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 705 8.4E-14 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 655 6.0E-9 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 757 2.5E-14 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 1.2E-11 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 551 9.9E-14 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 Gene3D G3DSA:2.120.10.90 497 807 1.0E-127 T 15-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I28_08040 4d191ac2191ae5fe8ac70f06ec678f8d 836 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 807 0.0 T 15-10-2018 C2I28_03310 9ebf7ea34dbeb16244ce23b14573f74c 449 Pfam PF03413 Peptidase propeptide and YPEB domain 376 431 1.2E-4 T 15-10-2018 IPR025711 PepSY domain C2I28_03310 9ebf7ea34dbeb16244ce23b14573f74c 449 Pfam PF14620 YpeB sporulation 14 373 3.2E-126 T 15-10-2018 IPR014239 Spore germination YpeB GO:0009847 C2I28_03310 9ebf7ea34dbeb16244ce23b14573f74c 449 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 439 7.9E-149 T 15-10-2018 IPR014239 Spore germination YpeB GO:0009847 C2I28_14935 ddb85f314c2d27c1ff65ec8ba39c68f0 139 SUPERFAMILY SSF54631 2 120 4.17E-33 T 15-10-2018 C2I28_14935 ddb85f314c2d27c1ff65ec8ba39c68f0 139 Gene3D G3DSA:3.10.580.10 1 123 2.2E-38 T 15-10-2018 C2I28_14935 ddb85f314c2d27c1ff65ec8ba39c68f0 139 SMART SM00116 75 122 1.2E-13 T 15-10-2018 IPR000644 CBS domain C2I28_14935 ddb85f314c2d27c1ff65ec8ba39c68f0 139 SMART SM00116 11 58 2.6E-7 T 15-10-2018 IPR000644 CBS domain C2I28_14935 ddb85f314c2d27c1ff65ec8ba39c68f0 139 Pfam PF00571 CBS domain 68 117 1.1E-14 T 15-10-2018 IPR000644 CBS domain C2I28_14935 ddb85f314c2d27c1ff65ec8ba39c68f0 139 Pfam PF00571 CBS domain 4 54 3.8E-9 T 15-10-2018 IPR000644 CBS domain C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 13 496 2.6E-227 T 15-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 12 171 6.9E-23 T 15-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 Gene3D G3DSA:3.40.1080.10 6 177 5.3E-14 T 15-10-2018 C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 Gene3D G3DSA:3.40.1080.20 338 478 2.6E-42 T 15-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 Gene3D G3DSA:3.30.750.70 249 327 7.8E-7 T 15-10-2018 C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 SUPERFAMILY SSF100950 6 224 6.7E-64 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 324 465 3.5E-44 T 15-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain C2I28_21690 ed53f29ee5e1ea7fd9b4e88bc29c0743 504 SUPERFAMILY SSF100950 228 498 6.63E-85 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_20375 69b6ed8eace52fed0ec0c615bf0f8407 479 SUPERFAMILY SSF55103 187 466 1.18E-16 T 15-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I28_20375 69b6ed8eace52fed0ec0c615bf0f8407 479 SUPERFAMILY SSF56176 34 211 1.12E-37 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_20375 69b6ed8eace52fed0ec0c615bf0f8407 479 Pfam PF01565 FAD binding domain 53 182 3.8E-28 T 15-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I28_20375 69b6ed8eace52fed0ec0c615bf0f8407 479 Gene3D G3DSA:3.30.465.10 101 227 5.2E-28 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_13830 5552c6caf82f0136fce7ece4d1f33b4d 452 PIRSF PIRSF002746 8 452 3.0E-159 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_13830 5552c6caf82f0136fce7ece4d1f33b4d 452 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 14 451 1.6E-151 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_13830 5552c6caf82f0136fce7ece4d1f33b4d 452 Pfam PF02447 GntP family permease 14 449 2.6E-165 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_13790 6c41fc9b560d890240da64c65ecc25fd 261 SUPERFAMILY SSF52266 92 256 1.83E-8 T 15-10-2018 C2I28_13790 6c41fc9b560d890240da64c65ecc25fd 261 Gene3D G3DSA:3.40.50.1110 79 258 7.6E-10 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_09860 5f2c8c8f14d95a5ae4b29f34a8b68b28 171 SUPERFAMILY SSF55068 1 165 3.01E-69 T 15-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_09860 5f2c8c8f14d95a5ae4b29f34a8b68b28 171 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 35.961 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_09860 5f2c8c8f14d95a5ae4b29f34a8b68b28 171 Pfam PF01625 Peptide methionine sulfoxide reductase 3 154 3.6E-59 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_09860 5f2c8c8f14d95a5ae4b29f34a8b68b28 171 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 153 1.5E-61 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_09860 5f2c8c8f14d95a5ae4b29f34a8b68b28 171 Gene3D G3DSA:3.30.1060.10 1 161 4.1E-63 T 15-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_21025 07a0048845317ee8ae214b8a2b1bd7c4 165 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 15-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I28_21025 07a0048845317ee8ae214b8a2b1bd7c4 165 Gene3D G3DSA:1.20.120.1760 1 164 5.6E-15 T 15-10-2018 C2I28_21025 07a0048845317ee8ae214b8a2b1bd7c4 165 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 16 161 2.4E-33 T 15-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 C2I28_21025 07a0048845317ee8ae214b8a2b1bd7c4 165 Pfam PF01066 CDP-alcohol phosphatidyltransferase 10 74 8.4E-16 T 15-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I28_03215 962dca94c28bc6926db968acdba807ca 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 15-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I28_03215 962dca94c28bc6926db968acdba807ca 321 Pfam PF00348 Polyprenyl synthetase 31 270 1.8E-69 T 15-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 C2I28_03215 962dca94c28bc6926db968acdba807ca 321 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 321 1.9E-163 T 15-10-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 C2I28_03215 962dca94c28bc6926db968acdba807ca 321 SUPERFAMILY SSF48576 7 320 5.76E-89 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_03215 962dca94c28bc6926db968acdba807ca 321 Gene3D G3DSA:1.10.600.10 7 321 1.2E-101 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_03215 962dca94c28bc6926db968acdba807ca 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 15-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I28_00390 ba1fa051e818c53b5f40d83fa47489fd 251 SUPERFAMILY SSF69118 1 248 1.85E-67 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_00390 ba1fa051e818c53b5f40d83fa47489fd 251 Pfam PF02627 Carboxymuconolactone decarboxylase family 163 244 1.0E-14 T 15-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_00390 ba1fa051e818c53b5f40d83fa47489fd 251 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 107 1.5E-18 T 15-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_00390 ba1fa051e818c53b5f40d83fa47489fd 251 Gene3D G3DSA:1.20.1290.10 20 251 5.4E-73 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_24355 5b05e2773b9e07cb8ae0a8fb9ad5cbcf 311 PRINTS PR00069 Aldo-keto reductase signature 106 124 5.7E-7 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_24355 5b05e2773b9e07cb8ae0a8fb9ad5cbcf 311 PRINTS PR00069 Aldo-keto reductase signature 190 219 5.7E-7 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_24355 5b05e2773b9e07cb8ae0a8fb9ad5cbcf 311 PRINTS PR00069 Aldo-keto reductase signature 239 263 5.7E-7 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_24355 5b05e2773b9e07cb8ae0a8fb9ad5cbcf 311 SUPERFAMILY SSF51430 1 306 6.29E-76 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_24355 5b05e2773b9e07cb8ae0a8fb9ad5cbcf 311 Pfam PF00248 Aldo/keto reductase family 16 302 2.5E-59 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_24355 5b05e2773b9e07cb8ae0a8fb9ad5cbcf 311 Gene3D G3DSA:3.20.20.100 1 311 1.8E-93 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 Pfam PF02310 B12 binding domain 9 122 1.9E-18 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 SMART SM00729 176 379 1.3E-22 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 Pfam PF04055 Radical SAM superfamily 180 344 1.7E-13 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 SUPERFAMILY SSF52242 42 149 5.1E-10 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 SUPERFAMILY SSF102114 168 419 1.07E-38 T 15-10-2018 C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 Gene3D G3DSA:3.40.50.280 11 137 5.1E-10 T 15-10-2018 C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 Gene3D G3DSA:3.80.30.20 174 368 4.7E-20 T 15-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I28_14230 17d763303ae69e910fc158d0c3b8c4d2 589 Pfam PF13311 Protein of unknown function (DUF4080) 372 563 8.3E-43 T 15-10-2018 IPR025288 Domain of unknown function DUF4080 C2I28_00115 2b224caf8d3cf501dc24e87a4cf064b5 132 Pfam PF07681 DoxX 5 93 3.4E-20 T 15-10-2018 IPR032808 DoxX family C2I28_10000 d2dc29274beb850f3463f32a5e28bdbe 372 Pfam PF13353 4Fe-4S single cluster domain 38 114 9.2E-6 T 15-10-2018 C2I28_10000 d2dc29274beb850f3463f32a5e28bdbe 372 Gene3D G3DSA:3.20.20.70 20 309 2.3E-22 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_10000 d2dc29274beb850f3463f32a5e28bdbe 372 Pfam PF08756 YfkB-like domain 218 366 7.7E-78 T 15-10-2018 IPR014866 YfkB-like domain C2I28_10000 d2dc29274beb850f3463f32a5e28bdbe 372 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 6 366 1.1E-194 T 15-10-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB C2I28_10000 d2dc29274beb850f3463f32a5e28bdbe 372 Pfam PF04055 Radical SAM superfamily 34 184 4.8E-11 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_10000 d2dc29274beb850f3463f32a5e28bdbe 372 SUPERFAMILY SSF102114 31 325 7.32E-27 T 15-10-2018 C2I28_23475 d08f1e19f6486092590532baaee72c0b 140 SUPERFAMILY SSF46955 18 101 2.06E-10 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_23475 d08f1e19f6486092590532baaee72c0b 140 Pfam PF13411 MerR HTH family regulatory protein 19 76 7.6E-8 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_23475 d08f1e19f6486092590532baaee72c0b 140 Gene3D G3DSA:1.10.1660.10 7 139 3.8E-11 T 15-10-2018 C2I28_23475 d08f1e19f6486092590532baaee72c0b 140 SMART SM00422 4 77 6.8E-4 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 SMART SM00257 185 228 1.4E-8 T 15-10-2018 IPR018392 LysM domain C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 Pfam PF01476 LysM domain 190 227 5.5E-11 T 15-10-2018 IPR018392 LysM domain C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 SUPERFAMILY SSF51261 34 155 7.32E-45 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 Gene3D G3DSA:2.70.70.10 24 157 4.7E-41 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 Pfam PF01551 Peptidase family M23 53 151 1.6E-30 T 15-10-2018 IPR016047 Peptidase M23 C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 Gene3D G3DSA:3.10.350.10 187 229 1.0E-12 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_03395 3b750e4c3cb1a235392602ca714531dc 229 SUPERFAMILY SSF54106 186 227 1.18E-8 T 15-10-2018 C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 ProSitePatterns PS00934 Glyoxalase I signature 1. 172 193 - T 15-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 SUPERFAMILY SSF54593 7 168 3.36E-41 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 Gene3D G3DSA:3.10.180.10 168 283 5.2E-19 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 Gene3D G3DSA:3.10.180.10 10 134 1.6E-29 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 SUPERFAMILY SSF54593 170 282 1.16E-22 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 124 8.8E-12 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_01465 0221caf040742245a2492a7bae9bdb0c 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 170 267 3.4E-4 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_13715 bba813df16a00b6905fc15d765eb1d69 460 Gene3D G3DSA:2.60.120.10 336 438 1.4E-15 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_13715 bba813df16a00b6905fc15d765eb1d69 460 Gene3D G3DSA:3.90.550.10 1 332 7.8E-89 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13715 bba813df16a00b6905fc15d765eb1d69 460 SUPERFAMILY SSF53448 1 265 2.94E-47 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13715 bba813df16a00b6905fc15d765eb1d69 460 Pfam PF01050 Mannose-6-phosphate isomerase 299 442 1.0E-22 T 15-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 C2I28_13715 bba813df16a00b6905fc15d765eb1d69 460 Pfam PF00483 Nucleotidyl transferase 4 269 1.0E-32 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_13715 bba813df16a00b6905fc15d765eb1d69 460 SUPERFAMILY SSF51182 189 443 1.36E-36 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_14420 ec6b8b5cf50f1dedfa20fe5d5b7ace5f 146 SUPERFAMILY SSF55620 13 139 1.06E-31 T 15-10-2018 C2I28_14420 ec6b8b5cf50f1dedfa20fe5d5b7ace5f 146 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 110 3.0E-27 T 15-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 C2I28_14420 ec6b8b5cf50f1dedfa20fe5d5b7ace5f 146 PIRSF PIRSF006113 13 140 1.9E-23 T 15-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 C2I28_14420 ec6b8b5cf50f1dedfa20fe5d5b7ace5f 146 Gene3D G3DSA:3.30.479.10 13 140 2.2E-28 T 15-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 C2I28_14420 ec6b8b5cf50f1dedfa20fe5d5b7ace5f 146 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 138 2.4E-28 T 15-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 Gene3D G3DSA:3.90.190.20 301 432 7.4E-33 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 15-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 15-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 377 2.8E-10 T 15-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 Pfam PF08245 Mur ligase middle domain 46 273 3.7E-20 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 SUPERFAMILY SSF53623 3 299 2.86E-98 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 PIRSF PIRSF001563 1 432 1.8E-163 T 15-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 SUPERFAMILY SSF53244 301 430 7.88E-28 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 Gene3D G3DSA:3.40.1190.10 3 300 4.3E-105 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_04930 26ab7ea8b68d356197bceda4a13a7b7f 432 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 429 3.8E-131 T 15-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 Gene3D G3DSA:3.40.50.720 4 329 1.7E-159 T 15-10-2018 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 PIRSF PIRSF000149 1 334 6.4E-142 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 SMART SM00846 3 152 1.2E-98 T 15-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 SUPERFAMILY SSF51735 3 168 1.28E-68 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 SUPERFAMILY SSF55347 152 314 5.66E-75 T 15-10-2018 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 9.3E-41 T 15-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.0E-42 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.0E-42 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.0E-42 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.0E-42 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.0E-42 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 9.4E-140 T 15-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 Gene3D G3DSA:3.30.360.10 151 315 1.7E-159 T 15-10-2018 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.1E-71 T 15-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06830 3c5cc03aae4f53d6e3cf0906ed9345cf 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 15-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 Pfam PF14102 Capsule biosynthesis CapC 12 128 8.9E-40 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 88 101 2.3E-44 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 20 37 2.3E-44 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 66 80 2.3E-44 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 118 132 2.3E-44 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 2 17 2.3E-44 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_13135 ccbb188cf2760c13521c42dcaebcdc4a 149 TIGRFAM TIGR04011 poly_gGlu_PgsC: poly-gamma-glutamate biosynthesis protein PgsC 10 139 3.1E-45 T 15-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 C2I28_19080 949cf47a8a10093cd706035b9d980d60 209 Gene3D G3DSA:3.40.50.1820 3 191 9.3E-6 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_19080 949cf47a8a10093cd706035b9d980d60 209 PIRSF PIRSF033634 1 209 1.7E-47 T 15-10-2018 IPR017018 Uncharacterised conserved protein UCP033634 C2I28_19080 949cf47a8a10093cd706035b9d980d60 209 SUPERFAMILY SSF53474 14 200 2.49E-7 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06500 bed1d8ce17b36f72d7f0f336dbf41a7e 250 PIRSF PIRSF021383 1 248 7.2E-74 T 15-10-2018 IPR014197 Sporulation protein YunB C2I28_06500 bed1d8ce17b36f72d7f0f336dbf41a7e 250 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 14 236 5.8E-57 T 15-10-2018 IPR014197 Sporulation protein YunB C2I28_06500 bed1d8ce17b36f72d7f0f336dbf41a7e 250 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 144 233 1.3E-30 T 15-10-2018 IPR014197 Sporulation protein YunB C2I28_22600 40219bbfe37235ee6be58053022f3bfa 244 Gene3D G3DSA:3.20.20.370 24 242 1.2E-60 T 15-10-2018 C2I28_22600 40219bbfe37235ee6be58053022f3bfa 244 SUPERFAMILY SSF88713 45 209 4.08E-30 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_22600 40219bbfe37235ee6be58053022f3bfa 244 Pfam PF01522 Polysaccharide deacetylase 77 198 1.4E-16 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 4.9E-19 T 15-10-2018 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 4.9E-19 T 15-10-2018 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 4.9E-19 T 15-10-2018 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 4.9E-19 T 15-10-2018 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 4.9E-19 T 15-10-2018 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 307 3.3E-27 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 Hamap MF_01685 Ferredoxin--NADP reductase. 6 333 36.767 T 15-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 7.1E-27 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 7.1E-27 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 7.1E-27 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 7.1E-27 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 7.1E-27 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 7.1E-27 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 Gene3D G3DSA:3.50.50.60 127 248 2.5E-85 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 SUPERFAMILY SSF51905 1 317 2.01E-36 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_15650 70beadee6e5a8e14405085d02cb81cbe 349 Gene3D G3DSA:3.50.50.60 7 309 2.5E-85 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 Gene3D G3DSA:3.20.20.100 2 310 4.4E-116 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 Pfam PF00248 Aldo/keto reductase family 16 308 5.8E-74 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 SUPERFAMILY SSF51430 4 309 1.3E-93 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 142 159 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 PRINTS PR00069 Aldo-keto reductase signature 242 266 3.8E-17 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 PRINTS PR00069 Aldo-keto reductase signature 45 69 3.8E-17 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 PRINTS PR00069 Aldo-keto reductase signature 142 159 3.8E-17 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13285 9896b3588092c43d9af161ecd31ee0f5 310 PRINTS PR00069 Aldo-keto reductase signature 111 129 3.8E-17 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_10750 30ecfd85f14bfe70364395d539a28f0e 524 Pfam PF02652 L-lactate permease 15 519 1.7E-175 T 15-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I28_10750 30ecfd85f14bfe70364395d539a28f0e 524 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 5 521 5.0E-183 T 15-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 SUPERFAMILY SSF55604 6 81 1.57E-20 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 3 461 3.0E-169 T 15-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 Gene3D G3DSA:3.30.1360.60 2 77 1.2E-24 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 Pfam PF02378 Phosphotransferase system, EIIC 110 407 1.1E-45 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 18 35 - T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 4 463 6.6E-204 T 15-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 Pfam PF00367 phosphotransferase system, EIIB 8 40 4.3E-16 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_12945 549675cf8afcab0979edb2779ec4f4b8 487 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 27 109 1.0E-20 T 15-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 Gene3D G3DSA:1.10.1660.10 2 128 8.5E-34 T 15-10-2018 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 SMART SM00422 3 72 2.8E-22 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.0E-6 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.0E-6 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.0E-6 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 Pfam PF13411 MerR HTH family regulatory protein 3 69 6.6E-19 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00845 03cc5cae32c30027411db46b876d9881 128 SUPERFAMILY SSF46955 3 116 1.65E-31 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_09880 66e4dcd836def61fe2e6ef8863775808 310 Gene3D G3DSA:3.40.50.720 30 300 1.6E-80 T 15-10-2018 C2I28_09880 66e4dcd836def61fe2e6ef8863775808 310 SUPERFAMILY SSF51735 98 275 2.19E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_09880 66e4dcd836def61fe2e6ef8863775808 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 275 7.3E-46 T 15-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I28_09880 66e4dcd836def61fe2e6ef8863775808 310 Gene3D G3DSA:3.40.50.720 96 279 1.6E-80 T 15-10-2018 C2I28_14605 e7262d22b69012dab25501f769686130 73 SMART SM00914 31 67 8.7E-9 T 15-10-2018 IPR014957 IDEAL domain C2I28_14605 e7262d22b69012dab25501f769686130 73 Pfam PF08858 IDEAL domain 34 67 1.2E-11 T 15-10-2018 IPR014957 IDEAL domain C2I28_14605 e7262d22b69012dab25501f769686130 73 Gene3D G3DSA:4.10.810.10 21 73 2.0E-12 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_16465 e2f310f83682309869d05c96d3811f8c 113 Gene3D G3DSA:1.20.58.280 4 108 3.3E-28 T 15-10-2018 C2I28_16465 e2f310f83682309869d05c96d3811f8c 113 SUPERFAMILY SSF46973 11 104 6.8E-28 T 15-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 C2I28_16465 e2f310f83682309869d05c96d3811f8c 113 PIRSF PIRSF000699 2 110 6.5E-30 T 15-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I28_16465 e2f310f83682309869d05c96d3811f8c 113 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 13 103 5.6E-27 T 15-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I28_00105 c9c34d9d924cb724d5587ee6d82efba0 188 Pfam PF03358 NADPH-dependent FMN reductase 5 146 1.8E-32 T 15-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I28_00105 c9c34d9d924cb724d5587ee6d82efba0 188 SUPERFAMILY SSF52218 4 176 6.45E-41 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_00105 c9c34d9d924cb724d5587ee6d82efba0 188 Gene3D G3DSA:3.40.50.360 1 183 1.1E-49 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_03525 2f4f016e9e9c451ee975737cf3901955 147 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 141 35.821 T 15-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I28_03525 2f4f016e9e9c451ee975737cf3901955 147 SMART SM00387 35 141 1.7E-11 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_03525 2f4f016e9e9c451ee975737cf3901955 147 Gene3D G3DSA:3.30.565.10 1 144 1.0E-33 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_03525 2f4f016e9e9c451ee975737cf3901955 147 Pfam PF13581 Histidine kinase-like ATPase domain 10 137 1.2E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_03525 2f4f016e9e9c451ee975737cf3901955 147 SUPERFAMILY SSF55874 28 135 3.27E-23 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_03525 2f4f016e9e9c451ee975737cf3901955 147 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 138 1.7E-69 T 15-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I28_11795 f77849ca6e137fbd0cd73925b4c0e36c 136 SUPERFAMILY SSF46458 7 124 2.02E-39 T 15-10-2018 IPR009050 Globin-like superfamily C2I28_11795 f77849ca6e137fbd0cd73925b4c0e36c 136 Pfam PF01152 Bacterial-like globin 9 123 5.7E-34 T 15-10-2018 IPR001486 Truncated hemoglobin GO:0019825 C2I28_11795 f77849ca6e137fbd0cd73925b4c0e36c 136 Gene3D G3DSA:1.10.490.10 3 130 4.5E-50 T 15-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I28_11795 f77849ca6e137fbd0cd73925b4c0e36c 136 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 15-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 SUPERFAMILY SSF55874 301 467 2.88E-37 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 Gene3D G3DSA:1.10.287.130 195 311 3.5E-29 T 15-10-2018 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 SMART SM00387 356 469 5.1E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 4.4E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 SUPERFAMILY SSF47384 229 310 1.08E-15 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 Gene3D G3DSA:3.30.565.10 318 470 1.7E-36 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 SMART SM00388 244 311 5.2E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 310 3.2E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 467 7.4E-25 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_00335 b3a59e2d14c8127dfbe3d9926ab05e20 472 SMART SM00304 190 243 9.8E-5 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_03980 5910ae9df03a8721e0d9e4078b2686b8 448 Gene3D G3DSA:3.40.640.10 84 349 1.1E-163 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_03980 5910ae9df03a8721e0d9e4078b2686b8 448 PIRSF PIRSF006815 3 447 4.8E-187 T 15-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 C2I28_03980 5910ae9df03a8721e0d9e4078b2686b8 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 49.9 T 15-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 C2I28_03980 5910ae9df03a8721e0d9e4078b2686b8 448 Gene3D G3DSA:3.90.1150.10 73 443 1.1E-163 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_03980 5910ae9df03a8721e0d9e4078b2686b8 448 Pfam PF02347 Glycine cleavage system P-protein 3 442 2.3E-165 T 15-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 C2I28_03980 5910ae9df03a8721e0d9e4078b2686b8 448 SUPERFAMILY SSF53383 3 443 5.44E-117 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_26190 3e8c1f68b1a1766e872e816766ce359b 93 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 75 9.0E-15 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_26190 3e8c1f68b1a1766e872e816766ce359b 93 SUPERFAMILY SSF52794 1 88 3.4E-18 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_26190 3e8c1f68b1a1766e872e816766ce359b 93 Gene3D G3DSA:3.40.50.2300 1 88 1.0E-18 T 15-10-2018 C2I28_00080 3e8c1f68b1a1766e872e816766ce359b 93 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 75 9.0E-15 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_00080 3e8c1f68b1a1766e872e816766ce359b 93 SUPERFAMILY SSF52794 1 88 3.4E-18 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_00080 3e8c1f68b1a1766e872e816766ce359b 93 Gene3D G3DSA:3.40.50.2300 1 88 1.0E-18 T 15-10-2018 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 ProSitePatterns PS00501 Signal peptidases I serine active site. 35 42 - T 15-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 26 42 1.3E-21 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 135 154 1.3E-21 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 1.3E-21 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 ProSitePatterns PS00761 Signal peptidases I signature 3. 140 153 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 SUPERFAMILY SSF51306 24 183 2.79E-48 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 Gene3D G3DSA:2.10.109.10 57 183 1.9E-46 T 15-10-2018 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 Pfam PF00717 Peptidase S24-like 33 101 9.5E-19 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 177 8.5E-51 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_16935 bb259c9241a75d8c790dcf2183614da1 184 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_11510 0f742247239f015f24746ab364cf7155 43 Pfam PF13081 Domain of unknown function (DUF3941) 19 41 7.0E-8 T 15-10-2018 IPR025077 Protein of unknown function DUF3941 C2I28_11900 28c68e05d083008c6c167e916abe2b4d 225 Gene3D G3DSA:3.30.240.20 80 155 7.5E-26 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_11900 28c68e05d083008c6c167e916abe2b4d 225 Gene3D G3DSA:3.30.240.20 169 225 4.5E-15 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_11900 28c68e05d083008c6c167e916abe2b4d 225 Pfam PF04239 Protein of unknown function (DUF421) 89 204 7.3E-33 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_02600 27c003d739b6213804ff3569e2773232 288 Gene3D G3DSA:1.10.1580.10 181 273 3.1E-31 T 15-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily C2I28_02600 27c003d739b6213804ff3569e2773232 288 Pfam PF01926 50S ribosome-binding GTPase 124 215 9.3E-18 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_02600 27c003d739b6213804ff3569e2773232 288 SUPERFAMILY SSF52540 9 194 2.08E-48 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02600 27c003d739b6213804ff3569e2773232 288 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 279 1.8E-117 T 15-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis C2I28_02600 27c003d739b6213804ff3569e2773232 288 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 124 144 6.9E-6 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_02600 27c003d739b6213804ff3569e2773232 288 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 185 6.9E-6 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_02600 27c003d739b6213804ff3569e2773232 288 PIRSF PIRSF006230 1 284 1.4E-104 T 15-10-2018 IPR016478 GTPase, MTG1 C2I28_02600 27c003d739b6213804ff3569e2773232 288 Gene3D G3DSA:3.40.50.300 12 180 9.0E-50 T 15-10-2018 C2I28_19745 1382da5a2b2bd9816746a172a12b5332 199 Pfam PF09335 SNARE associated Golgi protein 30 151 2.3E-12 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_21180 ade3579433a914317d52068507f260ea 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 1.3E-46 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_21180 ade3579433a914317d52068507f260ea 258 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 15-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_21180 ade3579433a914317d52068507f260ea 258 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 252 1.0E-115 T 15-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 C2I28_21180 ade3579433a914317d52068507f260ea 258 SUPERFAMILY SSF53790 2 242 1.07E-67 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_21180 ade3579433a914317d52068507f260ea 258 Gene3D G3DSA:3.30.950.10 111 231 1.8E-50 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_21180 ade3579433a914317d52068507f260ea 258 Gene3D G3DSA:3.40.1010.10 1 110 5.3E-37 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_06605 bd38543dcf526463951041997d7dd5aa 305 Pfam PF01619 Proline dehydrogenase 44 298 6.0E-34 T 15-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 C2I28_06605 bd38543dcf526463951041997d7dd5aa 305 SUPERFAMILY SSF51730 37 300 1.57E-76 T 15-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I28_06605 bd38543dcf526463951041997d7dd5aa 305 PIRSF PIRSF000196 1 305 7.9E-129 T 15-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 C2I28_06605 bd38543dcf526463951041997d7dd5aa 305 Gene3D G3DSA:3.20.20.530 19 305 2.7E-97 T 15-10-2018 C2I28_14845 302508b402df7e3b9cd824f0564a1bae 105 Pfam PF14036 YlaH-like protein 20 93 4.7E-30 T 15-10-2018 IPR025620 YlaH-like protein C2I28_17090 2cd5ba43e50c2e52cd196f3d949ff450 160 SUPERFAMILY SSF55826 8 157 1.83E-40 T 15-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I28_17090 2cd5ba43e50c2e52cd196f3d949ff450 160 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 8 156 3.5E-52 T 15-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC C2I28_17090 2cd5ba43e50c2e52cd196f3d949ff450 160 PIRSF PIRSF006181 3 160 6.0E-58 T 15-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC C2I28_17090 2cd5ba43e50c2e52cd196f3d949ff450 160 Pfam PF04073 Aminoacyl-tRNA editing domain 35 146 1.2E-24 T 15-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 C2I28_17090 2cd5ba43e50c2e52cd196f3d949ff450 160 Gene3D G3DSA:3.90.960.10 2 159 3.8E-51 T 15-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 SUPERFAMILY SSF55957 357 446 9.42E-28 T 15-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 6.7E-19 T 15-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 443 1.0E-184 T 15-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 1.2E-11 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 1.2E-11 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 1.2E-11 T 15-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 SUPERFAMILY SSF53738 158 256 3.69E-25 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Gene3D G3DSA:3.40.120.10 174 362 3.9E-71 T 15-10-2018 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.143 T 15-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Gene3D G3DSA:3.40.120.10 3 155 4.4E-58 T 15-10-2018 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 SUPERFAMILY SSF53738 257 366 2.83E-33 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 SUPERFAMILY SSF53738 3 180 1.61E-46 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 369 1.5E-36 T 15-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Gene3D G3DSA:3.30.310.50 370 448 1.0E-29 T 15-10-2018 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Gene3D G3DSA:3.40.120.10 256 339 3.9E-71 T 15-10-2018 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 1.0E-14 T 15-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 2.2E-43 T 15-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_08990 495461b718f342a91cebdd5107b2bcec 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 15-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 Gene3D G3DSA:3.30.70.980 83 234 7.4E-46 T 15-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 6.3E-71 T 15-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 56.527 T 15-10-2018 IPR026562 Probable transcriptional regulatory protein YeeN C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.545 T 15-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 Gene3D G3DSA:1.10.10.200 2 79 6.5E-25 T 15-10-2018 IPR017856 Integrase-like, N-terminal C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 SUPERFAMILY SSF75625 1 236 6.15E-81 T 15-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 Gene3D G3DSA:3.30.70.980 131 201 7.4E-46 T 15-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_09005 03dc09e6879bfa53c1d4641f08aae32f 238 Pfam PF01709 Transcriptional regulator 4 235 4.0E-82 T 15-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_24290 79156b6830bdee366872d430c2ee18f5 231 SUPERFAMILY SSF52540 7 229 6.9E-67 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_24290 79156b6830bdee366872d430c2ee18f5 231 Gene3D G3DSA:3.40.50.300 5 231 3.3E-73 T 15-10-2018 C2I28_24290 79156b6830bdee366872d430c2ee18f5 231 Pfam PF00005 ABC transporter 25 174 1.1E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_24290 79156b6830bdee366872d430c2ee18f5 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_24290 79156b6830bdee366872d430c2ee18f5 231 SMART SM00382 34 223 5.7E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 Gene3D G3DSA:3.30.260.10 135 408 8.9E-233 T 15-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 Gene3D G3DSA:1.10.560.10 7 518 8.9E-233 T 15-10-2018 IPR027413 GroEL-like equatorial domain superfamily C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.6E-98 T 15-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 Hamap MF_00600 60 kDa chaperonin [groL]. 1 542 42.411 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 8.0E-258 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 SUPERFAMILY SSF48592 5 518 3.83E-79 T 15-10-2018 IPR027413 GroEL-like equatorial domain superfamily C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 15-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 SUPERFAMILY SSF52029 183 374 8.55E-84 T 15-10-2018 IPR027409 GroEL-like apical domain superfamily C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 Gene3D G3DSA:3.50.7.10 190 370 8.9E-233 T 15-10-2018 IPR027409 GroEL-like apical domain superfamily C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 SUPERFAMILY SSF54849 136 204 4.81E-26 T 15-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 PRINTS PR00298 60kDa chaperonin signature 266 289 5.1E-73 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 PRINTS PR00298 60kDa chaperonin signature 82 109 5.1E-73 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 PRINTS PR00298 60kDa chaperonin signature 396 417 5.1E-73 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 PRINTS PR00298 60kDa chaperonin signature 26 52 5.1E-73 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_09345 973778509b2a32c8687f4f50c999ae34 543 PRINTS PR00298 60kDa chaperonin signature 348 373 5.1E-73 T 15-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 C2I28_08295 db7066ab0aa5f707bfe6f6d327dfd6d6 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 2.5E-11 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_08295 db7066ab0aa5f707bfe6f6d327dfd6d6 94 SMART SM00966 8 51 6.7E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_08295 db7066ab0aa5f707bfe6f6d327dfd6d6 94 SUPERFAMILY SSF89447 1 52 1.7E-16 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_08295 db7066ab0aa5f707bfe6f6d327dfd6d6 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.9E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_08295 db7066ab0aa5f707bfe6f6d327dfd6d6 94 Gene3D G3DSA:2.10.260.10 1 51 3.7E-26 T 15-10-2018 C2I28_18210 414148e036192a82e6400799eee7e32b 192 SUPERFAMILY SSF102405 2 179 2.29E-60 T 15-10-2018 C2I28_18210 414148e036192a82e6400799eee7e32b 192 Gene3D G3DSA:3.40.50.450 1 191 3.1E-78 T 15-10-2018 C2I28_18210 414148e036192a82e6400799eee7e32b 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 8.2E-67 T 15-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG C2I28_18210 414148e036192a82e6400799eee7e32b 192 Pfam PF03641 Possible lysine decarboxylase 46 176 2.7E-42 T 15-10-2018 IPR031100 LOG family C2I28_04245 55ed3180ad0475dd7e7a9a7b6705cb77 234 PIRSF PIRSF018637 4 234 1.4E-82 T 15-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 C2I28_04245 55ed3180ad0475dd7e7a9a7b6705cb77 234 SUPERFAMILY SSF53335 17 140 1.2E-5 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_04245 55ed3180ad0475dd7e7a9a7b6705cb77 234 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 231 1.6E-71 T 15-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 C2I28_04245 55ed3180ad0475dd7e7a9a7b6705cb77 234 Gene3D G3DSA:3.40.50.150 1 163 1.4E-52 T 15-10-2018 C2I28_26160 cec8a5dcc66e1e617aa833d522e1da3c 118 Pfam PF09946 Predicted membrane protein (DUF2178) 32 73 4.9E-5 T 15-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane C2I28_00050 cec8a5dcc66e1e617aa833d522e1da3c 118 Pfam PF09946 Predicted membrane protein (DUF2178) 32 73 4.9E-5 T 15-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane C2I28_16255 317d3f023e4151c59554fe9b10dee6b6 178 SUPERFAMILY SSF55729 4 143 2.38E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_16255 317d3f023e4151c59554fe9b10dee6b6 178 Pfam PF00583 Acetyltransferase (GNAT) family 31 134 4.1E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_16255 317d3f023e4151c59554fe9b10dee6b6 178 Gene3D G3DSA:3.40.630.30 1 178 7.3E-39 T 15-10-2018 C2I28_16925 eeb9618be213961481962139c56852c8 204 Pfam PF04892 VanZ like family 48 188 4.8E-25 T 15-10-2018 IPR006976 VanZ-like C2I28_18895 d0043589110478394cad59ea871e6fc8 114 SUPERFAMILY SSF47413 2 66 7.88E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_18895 d0043589110478394cad59ea871e6fc8 114 Gene3D G3DSA:1.10.260.40 1 112 6.2E-27 T 15-10-2018 C2I28_18895 d0043589110478394cad59ea871e6fc8 114 SMART SM00530 5 61 3.5E-16 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_18895 d0043589110478394cad59ea871e6fc8 114 Pfam PF01381 Helix-turn-helix 6 59 1.4E-16 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_12040 6fda4c3c44fbbf2d7f2f226ca25fc304 452 Pfam PF02378 Phosphotransferase system, EIIC 29 359 6.1E-78 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_12040 6fda4c3c44fbbf2d7f2f226ca25fc304 452 PIRSF PIRSF006351 1 441 4.0E-155 T 15-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I28_12040 6fda4c3c44fbbf2d7f2f226ca25fc304 452 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 434 2.1E-192 T 15-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I28_12040 6fda4c3c44fbbf2d7f2f226ca25fc304 452 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 434 2.1E-192 T 15-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I28_11465 15194271848a5e622e1df9648096709d 344 Gene3D G3DSA:3.40.50.2300 76 328 1.1E-82 T 15-10-2018 C2I28_11465 15194271848a5e622e1df9648096709d 344 Gene3D G3DSA:3.40.50.2300 167 329 1.1E-82 T 15-10-2018 C2I28_11465 15194271848a5e622e1df9648096709d 344 SUPERFAMILY SSF53822 63 338 2.01E-80 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_11465 15194271848a5e622e1df9648096709d 344 SMART SM00354 2 72 2.2E-29 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_11465 15194271848a5e622e1df9648096709d 344 Gene3D G3DSA:1.10.260.40 2 60 3.9E-23 T 15-10-2018 C2I28_11465 15194271848a5e622e1df9648096709d 344 Pfam PF13377 Periplasmic binding protein-like domain 175 336 1.8E-37 T 15-10-2018 C2I28_11465 15194271848a5e622e1df9648096709d 344 SUPERFAMILY SSF47413 3 60 6.49E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_11465 15194271848a5e622e1df9648096709d 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.4E-20 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19425 c81f33842d411d53c17cdd028b78286c 299 SUPERFAMILY SSF52540 2 218 7.5E-50 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19425 c81f33842d411d53c17cdd028b78286c 299 Pfam PF00005 ABC transporter 17 154 9.3E-25 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_19425 c81f33842d411d53c17cdd028b78286c 299 Gene3D G3DSA:3.40.50.300 1 226 2.9E-49 T 15-10-2018 C2I28_19425 c81f33842d411d53c17cdd028b78286c 299 SMART SM00382 26 203 9.4E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14995 9bf3ceba853bf95cf347c30c23515da7 277 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 5.9E-118 T 15-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I28_14995 9bf3ceba853bf95cf347c30c23515da7 277 Gene3D G3DSA:3.20.20.60 2 273 3.8E-114 T 15-10-2018 C2I28_14995 9bf3ceba853bf95cf347c30c23515da7 277 SUPERFAMILY SSF51621 3 263 1.14E-105 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_14995 9bf3ceba853bf95cf347c30c23515da7 277 PIRSF PIRSF000388 1 266 2.9E-109 T 15-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I28_14995 9bf3ceba853bf95cf347c30c23515da7 277 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 42.604 T 15-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I28_14995 9bf3ceba853bf95cf347c30c23515da7 277 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 259 1.0E-112 T 15-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 C2I28_16155 3cc42b680ea1be082461d018dd5d1b8c 223 SUPERFAMILY SSF56784 1 217 7.74E-41 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_16155 3cc42b680ea1be082461d018dd5d1b8c 223 Gene3D G3DSA:1.10.150.240 16 89 1.6E-33 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_16155 3cc42b680ea1be082461d018dd5d1b8c 223 Gene3D G3DSA:3.40.50.1000 5 205 1.6E-33 T 15-10-2018 IPR023214 HAD superfamily C2I28_16155 3cc42b680ea1be082461d018dd5d1b8c 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 185 6.4E-17 T 15-10-2018 C2I28_13375 30d3d3027f1f431e1ab2d406e3564f0f 104 Gene3D G3DSA:1.10.10.10 1 104 8.1E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13375 30d3d3027f1f431e1ab2d406e3564f0f 104 SUPERFAMILY SSF46785 2 103 6.02E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13375 30d3d3027f1f431e1ab2d406e3564f0f 104 Pfam PF01638 HxlR-like helix-turn-helix 17 103 2.9E-30 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_14000 12af437b22148dc74aa7f2ff2a1d565c 381 Gene3D G3DSA:3.40.1710.10 35 152 1.9E-8 T 15-10-2018 C2I28_14000 12af437b22148dc74aa7f2ff2a1d565c 381 Pfam PF12698 ABC-2 family transporter protein 16 370 9.1E-28 T 15-10-2018 C2I28_11445 ae4c078ad1735c031cc8f727b049133a 282 Pfam PF00494 Squalene/phytoene synthase 18 264 1.4E-67 T 15-10-2018 C2I28_11445 ae4c078ad1735c031cc8f727b049133a 282 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 158 183 - T 15-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 C2I28_11445 ae4c078ad1735c031cc8f727b049133a 282 Gene3D G3DSA:1.10.600.10 2 279 2.2E-98 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_11445 ae4c078ad1735c031cc8f727b049133a 282 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 127 142 - T 15-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 C2I28_11445 ae4c078ad1735c031cc8f727b049133a 282 SUPERFAMILY SSF48576 9 278 1.41E-76 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 1.9E-78 T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 SMART SM00963 2 87 9.0E-34 T 15-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Pfam PF02978 Signal peptide binding domain 329 427 1.5E-34 T 15-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Gene3D G3DSA:3.40.50.300 91 286 6.2E-128 T 15-10-2018 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 4.8E-191 T 15-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 SMART SM00962 101 297 1.4E-119 T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 442 35.198 T 15-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 SUPERFAMILY SSF47446 329 430 1.29E-38 T 15-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 SMART SM00382 100 275 2.2E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 4.9E-23 T 15-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Gene3D G3DSA:1.20.120.140 6 307 6.2E-128 T 15-10-2018 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 Gene3D G3DSA:1.10.260.30 328 445 1.5E-45 T 15-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 C2I28_02640 6b77d8cf76db4c4298fa0302e079464c 447 SUPERFAMILY SSF52540 43 355 6.11E-59 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 Gene3D G3DSA:3.20.20.140 80 378 6.7E-154 T 15-10-2018 C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 Pfam PF01979 Amidohydrolase family 255 418 3.0E-19 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 SUPERFAMILY SSF51338 35 422 5.99E-18 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 Hamap MF_00372 Imidazolonepropionase [hutI]. 5 418 37.865 T 15-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 417 5.6E-127 T 15-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 Gene3D G3DSA:2.30.40.10 9 416 6.7E-154 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_23710 de221cdc9e820acf4a4d32f3c2391742 425 SUPERFAMILY SSF51556 79 379 1.14E-67 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_01140 bedc0e08d6349e3de38b78f225cd1c9d 330 PIRSF PIRSF006278 2 330 1.7E-96 T 15-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase C2I28_01140 bedc0e08d6349e3de38b78f225cd1c9d 330 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 13 326 4.4E-99 T 15-10-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 C2I28_01140 bedc0e08d6349e3de38b78f225cd1c9d 330 SUPERFAMILY SSF53686 5 329 1.78E-86 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_01140 bedc0e08d6349e3de38b78f225cd1c9d 330 Gene3D G3DSA:3.40.50.1100 14 323 9.4E-113 T 15-10-2018 C2I28_01140 bedc0e08d6349e3de38b78f225cd1c9d 330 Gene3D G3DSA:3.40.50.1100 48 155 9.4E-113 T 15-10-2018 C2I28_01140 bedc0e08d6349e3de38b78f225cd1c9d 330 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 14 317 9.1E-57 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 ProSitePatterns PS01053 Arginase family signature. 237 258 - T 15-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 Gene3D G3DSA:3.40.800.10 2 314 2.7E-103 T 15-10-2018 C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 PIRSF PIRSF036979 13 313 1.1E-96 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 TIGRFAM TIGR01230 agmatinase: agmatinase 30 307 1.3E-66 T 15-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 Pfam PF00491 Arginase family 35 305 1.1E-82 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 SUPERFAMILY SSF52768 13 311 4.14E-95 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 PRINTS PR00116 Arginase signature 121 136 1.1E-13 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_19365 5fdce00a51bc577f8d3c67899985e3f8 328 PRINTS PR00116 Arginase signature 234 263 1.1E-13 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_24230 1b4a10595aaa81676fff9a7e4fb8148b 425 Gene3D G3DSA:3.40.50.2000 3 404 8.7E-101 T 15-10-2018 C2I28_24230 1b4a10595aaa81676fff9a7e4fb8148b 425 SUPERFAMILY SSF53756 1 419 2.1E-86 T 15-10-2018 C2I28_24230 1b4a10595aaa81676fff9a7e4fb8148b 425 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 321 410 8.4E-7 T 15-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 C2I28_24230 1b4a10595aaa81676fff9a7e4fb8148b 425 Gene3D G3DSA:3.40.50.2000 232 402 8.7E-101 T 15-10-2018 C2I28_24230 1b4a10595aaa81676fff9a7e4fb8148b 425 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 140 9.3E-12 T 15-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 Gene3D G3DSA:3.20.20.80 53 452 9.3E-158 T 15-10-2018 C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 SUPERFAMILY SSF51445 48 457 1.95E-112 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 Gene3D G3DSA:3.90.400.10 160 224 9.3E-158 T 15-10-2018 C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 Pfam PF11941 Domain of unknown function (DUF3459) 444 527 5.2E-8 T 15-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 Pfam PF00128 Alpha amylase, catalytic domain 70 394 9.8E-85 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 SMART SM00642 55 451 1.2E-123 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_20460 9a0b2ded0a131a4510a1017759ed9464 531 SUPERFAMILY SSF51011 460 502 2.32E-5 T 15-10-2018 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 46.095 T 15-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 SUPERFAMILY SSF51735 2 146 2.79E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 128 1.4E-38 T 15-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 PIRSF PIRSF006205 1 382 1.6E-157 T 15-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 Gene3D G3DSA:3.40.50.720 1 146 2.0E-47 T 15-10-2018 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 Pfam PF13288 DXP reductoisomerase C-terminal domain 257 374 2.2E-42 T 15-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 SUPERFAMILY SSF55347 122 260 2.03E-61 T 15-10-2018 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 7.2E-162 T 15-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 Gene3D G3DSA:1.10.1740.10 299 382 6.3E-28 T 15-10-2018 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 SUPERFAMILY SSF69055 289 381 4.84E-30 T 15-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_02360 c5383ed71bfdfa4b0cf97838d8ac4f42 382 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 142 225 1.1E-41 T 15-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 C2I28_26740 fde716206037a90d2f847552aa7ab7ee 443 PIRSF PIRSF002746 2 443 1.4E-143 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_26740 fde716206037a90d2f847552aa7ab7ee 443 Pfam PF02447 GntP family permease 7 441 4.3E-144 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_26740 fde716206037a90d2f847552aa7ab7ee 443 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 7 442 1.2E-136 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 Gene3D G3DSA:3.40.50.880 159 352 1.0E-32 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 348 1.5E-139 T 15-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 270 6.1E-32 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 167 181 6.1E-32 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 289 6.1E-32 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 236 252 6.1E-32 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 206 220 6.1E-32 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 SMART SM01097 1 132 1.3E-63 T 15-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 Pfam PF00117 Glutamine amidotransferase class-I 169 344 1.0E-44 T 15-10-2018 IPR017926 Glutamine amidotransferase C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 Gene3D G3DSA:3.50.30.20 1 157 3.4E-50 T 15-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00096 Glutamine amidotransferase superfamily signature 322 335 1.6E-11 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 247 1.6E-11 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 PRINTS PR00096 Glutamine amidotransferase superfamily signature 209 218 1.6E-11 T 15-10-2018 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 SUPERFAMILY SSF52021 1 137 7.06E-47 T 15-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 9.5E-46 T 15-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 SUPERFAMILY SSF52317 148 347 1.01E-52 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_11565 2a41d86c404f734185d308ccf9d8485c 357 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 351 43.978 T 15-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_07015 6a7edf3d8dcd7dd6ae5a32c1a80f076a 402 SUPERFAMILY SSF51261 194 400 4.81E-44 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_07015 6a7edf3d8dcd7dd6ae5a32c1a80f076a 402 Gene3D G3DSA:2.70.70.10 254 401 3.4E-39 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_07015 6a7edf3d8dcd7dd6ae5a32c1a80f076a 402 Pfam PF01551 Peptidase family M23 293 395 3.0E-26 T 15-10-2018 IPR016047 Peptidase M23 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 42 214 1.0E-62 T 15-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 707 850 3.1E-28 T 15-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 SUPERFAMILY SSF75005 32 215 8.16E-73 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 SUPERFAMILY SSF75005 706 857 3.14E-28 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 42 55 - T 15-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 SUPERFAMILY SSF49899 868 1019 8.7E-34 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 860 1013 8.2E-37 T 15-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Gene3D G3DSA:2.115.10.20 660 864 2.3E-38 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Gene3D G3DSA:2.60.120.560 865 1020 2.6E-48 T 15-10-2018 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Pfam PF06439 Domain of Unknown Function (DUF1080) 1025 1187 2.5E-6 T 15-10-2018 IPR010496 Domain of unknown function DUF1080 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Pfam PF06439 Domain of Unknown Function (DUF1080) 201 356 7.0E-9 T 15-10-2018 IPR010496 Domain of unknown function DUF1080 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Gene3D G3DSA:2.60.120.560 358 517 2.8E-35 T 15-10-2018 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Gene3D G3DSA:2.60.120.560 1022 1188 4.1E-35 T 15-10-2018 C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 Gene3D G3DSA:2.115.10.20 32 282 1.1E-80 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15930 771357f143ccb9588c9ae7527e20ac46 1192 SMART SM00640 42 979 4.5E-135 T 15-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 1.4E-37 T 15-10-2018 IPR039518 WhiA, LAGLIDADG-like domain C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.1E-35 T 15-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 Gene3D G3DSA:3.10.28.10 1 214 1.1E-67 T 15-10-2018 IPR027434 Homing endonuclease C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 Gene3D G3DSA:1.10.10.10 215 309 1.9E-37 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 36.018 T 15-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 SUPERFAMILY SSF55608 120 221 7.37E-20 T 15-10-2018 IPR027434 Homing endonuclease C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 1.5E-36 T 15-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain C2I28_06870 8caa9d816cc85491d05dc7914ad79bea 314 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 1.2E-133 T 15-10-2018 IPR033981 Sporulation regulator WhiA-like C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SUPERFAMILY SSF50044 209 248 6.43E-5 T 15-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Gene3D G3DSA:3.30.1380.10 241 442 8.2E-76 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SMART SM00287 111 173 4.9E-11 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SMART SM00287 184 246 1.3E-11 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SMART SM00287 44 108 4.2E-13 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SUPERFAMILY SSF50044 136 186 2.44E-5 T 15-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Gene3D G3DSA:2.30.30.40 108 172 4.5E-19 T 15-10-2018 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SUPERFAMILY SSF55166 278 428 1.86E-34 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Pfam PF08239 Bacterial SH3 domain 54 105 2.0E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Pfam PF08239 Bacterial SH3 domain 120 171 1.9E-13 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Pfam PF08239 Bacterial SH3 domain 193 243 9.8E-13 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 293 422 2.4E-40 T 15-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Gene3D G3DSA:2.30.30.40 184 240 1.4E-17 T 15-10-2018 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 Gene3D G3DSA:2.30.30.40 45 106 2.8E-21 T 15-10-2018 C2I28_25355 f50b44444752b52a1b687798c0fd81fa 442 SUPERFAMILY SSF50044 70 116 9.62E-7 T 15-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 138 154 - T 15-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 SUPERFAMILY SSF48557 3 492 3.92E-198 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 Gene3D G3DSA:1.20.200.10 197 499 4.0E-125 T 15-10-2018 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 Pfam PF00221 Aromatic amino acid lyase 10 468 3.9E-198 T 15-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 3 487 2.0E-215 T 15-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 2 501 45.212 T 15-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16000 a4fdd2edcc7932bb1484d8d68194a3aa 503 Gene3D G3DSA:1.10.275.10 1 196 5.9E-71 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_03650 2ce3d2e04a514df2627a5d8da1c36ed0 452 Gene3D G3DSA:3.90.1150.10 15 447 8.0E-148 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_03650 2ce3d2e04a514df2627a5d8da1c36ed0 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_03650 2ce3d2e04a514df2627a5d8da1c36ed0 452 PIRSF PIRSF000521 23 451 5.4E-41 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_03650 2ce3d2e04a514df2627a5d8da1c36ed0 452 SUPERFAMILY SSF53383 20 449 9.32E-123 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_03650 2ce3d2e04a514df2627a5d8da1c36ed0 452 Pfam PF00202 Aminotransferase class-III 30 447 1.9E-108 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_03650 2ce3d2e04a514df2627a5d8da1c36ed0 452 Gene3D G3DSA:3.40.640.10 66 340 8.0E-148 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 SUPERFAMILY SSF53901 3 249 3.23E-52 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 361 1.7E-14 T 15-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 SUPERFAMILY SSF53901 213 403 7.41E-34 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 Gene3D G3DSA:3.40.47.10 259 405 4.5E-17 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.7E-33 T 15-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 Gene3D G3DSA:3.40.47.10 1 254 2.7E-63 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_26485 43d494ca286c270134a15fd01ec94b7b 405 SMART SM00825 Beta-ketoacyl synthase 5 363 2.8E-5 T 15-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SUPERFAMILY SSF55874 366 521 9.43E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 Gene3D G3DSA:1.10.287.130 300 372 2.0E-17 T 15-10-2018 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 Gene3D G3DSA:3.30.450.20 190 299 2.9E-25 T 15-10-2018 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 Pfam PF00512 His Kinase A (phospho-acceptor) domain 313 370 4.5E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SUPERFAMILY SSF47384 304 371 1.59E-12 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 182 302 9.2E-26 T 15-10-2018 IPR000014 PAS domain C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SMART SM00086 254 296 2.8E-7 T 15-10-2018 IPR001610 PAC motif C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SMART SM00388 311 374 6.8E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SUPERFAMILY SSF55785 173 294 3.66E-21 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 Pfam PF13426 PAS domain 196 295 4.2E-15 T 15-10-2018 IPR000014 PAS domain C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 481 1.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 1.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 1.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 1.0E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 417 520 7.9E-19 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SMART SM00387 416 522 2.0E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 SMART SM00091 183 251 1.0E-4 T 15-10-2018 IPR000014 PAS domain C2I28_14365 61a92cce8719c6d57c3890ea09dac936 527 Gene3D G3DSA:3.30.565.10 375 524 1.5E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_15835 d1a321da8e671a38f9c732ea94c149f8 447 Pfam PF00324 Amino acid permease 21 387 1.2E-55 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_15835 d1a321da8e671a38f9c732ea94c149f8 447 PIRSF PIRSF006060 8 444 1.1E-50 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_15835 d1a321da8e671a38f9c732ea94c149f8 447 Gene3D G3DSA:1.20.1740.10 11 446 1.0E-49 T 15-10-2018 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 Gene3D G3DSA:3.40.605.10 14 428 8.0E-177 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 SUPERFAMILY SSF53720 7 431 3.53E-126 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 Gene3D G3DSA:3.40.309.10 213 408 8.0E-177 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 Pfam PF00171 Aldehyde dehydrogenase family 21 428 7.5E-98 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_24795 4e6ee4d93b638286ec7492907d2ce707 434 PIRSF PIRSF036492 1 434 3.5E-185 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_02145 532cffdecccfe42ebf10f68dc5e7f419 86 Gene3D G3DSA:3.30.110.20 1 86 4.6E-37 T 15-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 C2I28_02145 532cffdecccfe42ebf10f68dc5e7f419 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 5.0E-33 T 15-10-2018 IPR007347 Sporulation stage V, protein S C2I28_02145 532cffdecccfe42ebf10f68dc5e7f419 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 9.9E-41 T 15-10-2018 IPR007347 Sporulation stage V, protein S C2I28_16485 4852617e8e5c9c707897e403abd90494 297 SUPERFAMILY SSF53067 1 287 1.3E-43 T 15-10-2018 C2I28_16485 4852617e8e5c9c707897e403abd90494 297 Gene3D G3DSA:3.30.420.40 1 99 1.1E-14 T 15-10-2018 C2I28_16485 4852617e8e5c9c707897e403abd90494 297 Gene3D G3DSA:3.30.420.40 102 293 1.0E-43 T 15-10-2018 C2I28_16485 4852617e8e5c9c707897e403abd90494 297 Pfam PF00480 ROK family 5 285 7.0E-35 T 15-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_16485 4852617e8e5c9c707897e403abd90494 297 ProSitePatterns PS01125 ROK family signature. 128 155 - T 15-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Gene3D G3DSA:3.40.50.280 710 860 1.0E-47 T 15-10-2018 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 899 1146 6.8E-60 T 15-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Gene3D G3DSA:1.10.1240.10 616 703 3.8E-27 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 SUPERFAMILY SSF82282 3 378 9.29E-114 T 15-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 SMART SM01018 623 706 6.6E-36 T 15-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 SUPERFAMILY SSF56507 871 1146 6.41E-89 T 15-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Pfam PF02607 B12 binding domain 626 699 3.0E-23 T 15-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 TIGRFAM TIGR02082 metH: methionine synthase 9 1146 0.0 T 15-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Gene3D G3DSA:3.20.20.20 320 615 4.1E-104 T 15-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Gene3D G3DSA:1.10.288.10 898 956 2.2E-66 T 15-10-2018 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Pfam PF00809 Pterin binding enzyme 339 572 1.2E-42 T 15-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 SUPERFAMILY SSF47644 620 704 1.27E-23 T 15-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Gene3D G3DSA:3.20.20.330 1 319 4.8E-109 T 15-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 SUPERFAMILY SSF51717 336 600 3.53E-81 T 15-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Pfam PF02310 B12 binding domain 713 802 1.7E-19 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Pfam PF02574 Homocysteine S-methyltransferase 14 304 2.4E-77 T 15-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 PIRSF PIRSF000381 1 1147 0.0 T 15-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 SUPERFAMILY SSF52242 707 841 5.49E-40 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_14505 417877c7cb8ecbf086a01939c34c56ca 1147 Gene3D G3DSA:3.10.196.10 885 1146 2.2E-66 T 15-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_13440 0b73068192f459e52d9ee05ba8fdbd82 291 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 85 284 1.9E-39 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_13440 0b73068192f459e52d9ee05ba8fdbd82 291 SUPERFAMILY SSF53187 83 286 1.32E-33 T 15-10-2018 C2I28_13440 0b73068192f459e52d9ee05ba8fdbd82 291 SMART SM00646 165 284 2.5E-10 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_13440 0b73068192f459e52d9ee05ba8fdbd82 291 Gene3D G3DSA:3.40.630.40 83 289 3.6E-44 T 15-10-2018 C2I28_19975 d2594ec8edc3cc2299f32d5d967cc2d9 390 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_19975 d2594ec8edc3cc2299f32d5d967cc2d9 390 Gene3D G3DSA:3.40.50.1970 1 184 2.4E-53 T 15-10-2018 C2I28_19975 d2594ec8edc3cc2299f32d5d967cc2d9 390 SUPERFAMILY SSF56796 2 388 1.7E-112 T 15-10-2018 C2I28_19975 d2594ec8edc3cc2299f32d5d967cc2d9 390 Gene3D G3DSA:1.20.1090.10 185 389 1.3E-41 T 15-10-2018 C2I28_19975 d2594ec8edc3cc2299f32d5d967cc2d9 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 379 4.9E-95 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_19975 d2594ec8edc3cc2299f32d5d967cc2d9 390 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_16250 2c110d14e77874b00e23d2f021bac91c 167 SUPERFAMILY SSF109854 3 141 1.16E-23 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16250 2c110d14e77874b00e23d2f021bac91c 167 Gene3D G3DSA:1.20.120.450 1 150 2.3E-36 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16250 2c110d14e77874b00e23d2f021bac91c 167 Pfam PF05163 DinB family 2 157 1.1E-26 T 15-10-2018 IPR007837 DNA damage-inducible protein DinB C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 SMART SM00641 9 112 2.8E-14 T 15-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 Pfam PF01471 Putative peptidoglycan binding domain 230 287 6.5E-17 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 13 46 - T 15-10-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 Gene3D G3DSA:1.10.101.10 218 299 7.6E-19 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 Gene3D G3DSA:3.20.20.80 1 217 1.8E-69 T 15-10-2018 C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 Pfam PF01183 Glycosyl hydrolases family 25 12 191 2.7E-47 T 15-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 SUPERFAMILY SSF47090 222 288 5.76E-18 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_20155 c559fe4840dd66e63336b58a97232f6a 433 SUPERFAMILY SSF51445 7 203 2.6E-52 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_12165 a9fc81cde488e636d72a6437057a4060 285 Gene3D G3DSA:1.10.4200.10 164 280 4.8E-9 T 15-10-2018 C2I28_12165 a9fc81cde488e636d72a6437057a4060 285 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 18 277 2.6E-71 T 15-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 C2I28_12165 a9fc81cde488e636d72a6437057a4060 285 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 17 279 1.6E-92 T 15-10-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 C2I28_12165 a9fc81cde488e636d72a6437057a4060 285 Hamap MF_01883 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [mdcB]. 1 285 125.23 T 15-10-2018 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SUPERFAMILY SSF55874 561 710 6.55E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Pfam PF02743 Cache domain 39 267 1.9E-30 T 15-10-2018 IPR033479 Double Cache domain 1 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SMART SM00388 501 564 4.4E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 606 708 2.9E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SUPERFAMILY SSF103190 199 262 8.63E-7 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Gene3D G3DSA:3.30.565.10 564 713 3.4E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Gene3D G3DSA:1.10.8.500 304 357 1.6E-7 T 15-10-2018 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Pfam PF00512 His Kinase A (phospho-acceptor) domain 503 560 2.0E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Pfam PF13426 PAS domain 389 485 8.6E-9 T 15-10-2018 IPR000014 PAS domain C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SMART SM00304 305 359 4.6E-9 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Gene3D G3DSA:3.30.450.20 359 489 1.7E-21 T 15-10-2018 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SUPERFAMILY SSF158472 305 356 2.62E-7 T 15-10-2018 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Pfam PF00672 HAMP domain 305 355 3.9E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SUPERFAMILY SSF55785 361 484 9.77E-15 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SMART SM00086 444 486 0.0053 T 15-10-2018 IPR001610 PAC motif C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Gene3D G3DSA:1.10.287.130 490 563 1.2E-18 T 15-10-2018 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SMART SM00387 606 712 5.4E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 Gene3D G3DSA:3.30.450.20 145 286 1.1E-20 T 15-10-2018 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 696 709 1.3E-10 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 672 690 1.3E-10 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 643 657 1.3E-10 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 671 1.3E-10 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 369 493 1.1E-16 T 15-10-2018 IPR000014 PAS domain C2I28_10035 1f1d016f6e713db14d29c2fc0908b1f4 713 SUPERFAMILY SSF47384 494 561 2.16E-12 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_22935 306748eea0637d4ed5942eb843554be9 204 Gene3D G3DSA:3.40.50.300 3 200 3.9E-50 T 15-10-2018 C2I28_22935 306748eea0637d4ed5942eb843554be9 204 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 4 198 1.9E-100 T 15-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 C2I28_22935 306748eea0637d4ed5942eb843554be9 204 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 176 1.1E-38 T 15-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain C2I28_22935 306748eea0637d4ed5942eb843554be9 204 SUPERFAMILY SSF52540 4 195 2.16E-33 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_22935 306748eea0637d4ed5942eb843554be9 204 Hamap MF_01389 Urease accessory protein UreG [ureG]. 2 200 45.949 T 15-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 C2I28_22935 306748eea0637d4ed5942eb843554be9 204 PIRSF PIRSF005624 1 202 4.1E-48 T 15-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 C2I28_24390 d6866267160f3a03d4bef97cfc507b6e 94 Pfam PF05121 Gas vesicle protein K 10 94 3.2E-35 T 15-10-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 C2I28_10355 f8ca8a0e6d747ab3d7aa3c8a8c85a14b 392 Pfam PF04285 Protein of unknown function (DUF444) 197 385 3.2E-68 T 15-10-2018 IPR006698 Uncharacterised protein family UPF0229 C2I28_10355 f8ca8a0e6d747ab3d7aa3c8a8c85a14b 392 Pfam PF04285 Protein of unknown function (DUF444) 15 189 4.0E-35 T 15-10-2018 IPR006698 Uncharacterised protein family UPF0229 C2I28_10355 f8ca8a0e6d747ab3d7aa3c8a8c85a14b 392 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 9 382 2.6E-183 T 15-10-2018 IPR014230 Sporulation protein YhbH C2I28_10355 f8ca8a0e6d747ab3d7aa3c8a8c85a14b 392 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 387 32.042 T 15-10-2018 IPR006698 Uncharacterised protein family UPF0229 C2I28_10355 f8ca8a0e6d747ab3d7aa3c8a8c85a14b 392 SUPERFAMILY SSF53300 218 340 5.08E-5 T 15-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 SMART SM00382 56 227 3.0E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 SUPERFAMILY SSF52540 2 266 4.02E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 Gene3D G3DSA:3.40.50.300 25 266 2.3E-77 T 15-10-2018 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 Pfam PF00154 recA bacterial DNA recombination protein 7 267 3.1E-142 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 Hamap MF_00268 Protein RecA [recA]. 4 328 52.086 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 PRINTS PR00142 RecA protein signature 209 237 5.4E-86 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 PRINTS PR00142 RecA protein signature 92 121 5.4E-86 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 PRINTS PR00142 RecA protein signature 126 155 5.4E-86 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 PRINTS PR00142 RecA protein signature 296 313 5.4E-86 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 PRINTS PR00142 RecA protein signature 164 193 5.4E-86 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 PRINTS PR00142 RecA protein signature 242 271 5.4E-86 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 321 1.2E-169 T 15-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 ProSitePatterns PS00321 recA signature. 212 220 - T 15-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 Gene3D G3DSA:3.30.250.10 267 325 2.9E-26 T 15-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal C2I28_16800 d709ed016fb8e87eddc7364e7da23aca 345 SUPERFAMILY SSF54752 267 323 4.45E-21 T 15-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal C2I28_04890 3eb2fc89b82528f41a192f8d111b842c 293 Gene3D G3DSA:2.40.10.340 121 275 4.4E-53 T 15-10-2018 C2I28_04890 3eb2fc89b82528f41a192f8d111b842c 293 PIRSF PIRSF038471 2 291 2.5E-63 T 15-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I28_04890 3eb2fc89b82528f41a192f8d111b842c 293 Gene3D G3DSA:2.40.10.350 182 264 4.4E-53 T 15-10-2018 C2I28_04890 3eb2fc89b82528f41a192f8d111b842c 293 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 7 281 4.0E-66 T 15-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I28_04890 3eb2fc89b82528f41a192f8d111b842c 293 Pfam PF04085 rod shape-determining protein MreC 123 276 1.7E-44 T 15-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 C2I28_10075 7fee6e34552acf09cc907d3f67f17686 51 Pfam PF08176 Small acid-soluble spore protein K family 1 47 8.1E-29 T 15-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 C2I28_10075 7fee6e34552acf09cc907d3f67f17686 51 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 16 47 1.2E-23 T 15-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 C2I28_10075 7fee6e34552acf09cc907d3f67f17686 51 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 49 18.155 T 15-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 C2I28_10915 54caa57a3bfd4f422c58527ef010cf07 339 Gene3D G3DSA:3.40.50.720 1 251 3.8E-71 T 15-10-2018 C2I28_10915 54caa57a3bfd4f422c58527ef010cf07 339 Pfam PF00899 ThiF family 5 240 9.4E-57 T 15-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I28_10915 54caa57a3bfd4f422c58527ef010cf07 339 SUPERFAMILY SSF69572 3 327 3.14E-80 T 15-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:1.20.1640.10 11 529 5.4E-275 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:3.30.70.1430 578 671 5.4E-275 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Pfam PF00873 AcrB/AcrD/AcrF family 4 1026 1.2E-215 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:3.30.70.1430 41 817 5.4E-275 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 355 378 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 491 514 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 382 403 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 410 434 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.4E-47 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:3.30.2090.10 721 809 5.4E-275 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 SUPERFAMILY SSF82714 723 807 1.57E-9 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 SUPERFAMILY SSF82693 133 336 4.71E-16 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 SUPERFAMILY SSF82714 185 245 5.49E-6 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:3.30.70.1440 672 866 5.4E-275 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 SUPERFAMILY SSF82866 316 517 2.75E-43 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:3.30.2090.10 177 295 5.4E-275 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 SUPERFAMILY SSF82693 41 133 3.4E-22 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:3.30.70.1320 133 351 5.4E-275 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 Gene3D G3DSA:1.20.1640.10 530 1023 5.4E-275 T 15-10-2018 C2I28_06645 c1c14b85300862adc72c13ade5195a3c 1036 SUPERFAMILY SSF82866 809 1032 4.84E-47 T 15-10-2018 C2I28_16345 f0017a5c8dcf94e88ada896925292055 399 Pfam PF00534 Glycosyl transferases group 1 229 355 2.0E-10 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_16345 f0017a5c8dcf94e88ada896925292055 399 Gene3D G3DSA:3.40.50.2000 197 359 1.2E-29 T 15-10-2018 C2I28_16345 f0017a5c8dcf94e88ada896925292055 399 SUPERFAMILY SSF53756 86 366 2.31E-33 T 15-10-2018 C2I28_16345 f0017a5c8dcf94e88ada896925292055 399 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 20 185 2.2E-28 T 15-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 C2I28_27385 44acc2f05108be9c9d5d36ab2093ddf6 247 Gene3D G3DSA:1.10.510.10 54 213 1.4E-8 T 15-10-2018 C2I28_27385 44acc2f05108be9c9d5d36ab2093ddf6 247 SUPERFAMILY SSF56112 76 209 1.52E-14 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_04370 93fa51ca143f2f0295cf19231bb61d3c 313 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 3.9E-100 T 15-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 C2I28_04370 93fa51ca143f2f0295cf19231bb61d3c 313 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 1.1E-107 T 15-10-2018 C2I28_04370 93fa51ca143f2f0295cf19231bb61d3c 313 PIRSF PIRSF000401 1 313 3.5E-112 T 15-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 C2I28_04370 93fa51ca143f2f0295cf19231bb61d3c 313 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.363 T 15-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 C2I28_04370 93fa51ca143f2f0295cf19231bb61d3c 313 Gene3D G3DSA:3.40.50.150 116 313 3.1E-65 T 15-10-2018 C2I28_04370 93fa51ca143f2f0295cf19231bb61d3c 313 SUPERFAMILY SSF53335 96 310 2.26E-47 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_07395 3a5d62f645210b37e4073bf84ca678b8 186 Pfam PF02659 Putative manganese efflux pump 36 183 5.6E-40 T 15-10-2018 IPR003810 Putative manganese efflux pump C2I28_07395 3a5d62f645210b37e4073bf84ca678b8 186 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 8 186 21.746 T 15-10-2018 IPR022929 Putative manganese efflux pump MntP C2I28_12555 0dde73e4efb6c82965fcb527a87b2f24 338 SUPERFAMILY SSF81345 11 334 5.23E-89 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_12555 0dde73e4efb6c82965fcb527a87b2f24 338 Pfam PF01032 FecCD transport family 26 334 3.0E-96 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_12555 0dde73e4efb6c82965fcb527a87b2f24 338 Gene3D G3DSA:1.10.3470.10 13 338 4.9E-102 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_18380 45bc6b871a1955e40b9b99cdbdec2cee 760 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 76 234 9.2E-33 T 15-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PIRSF PIRSF006615 2 498 6.7E-153 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 Gene3D G3DSA:1.10.1370.30 3 498 1.2E-165 T 15-10-2018 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 SUPERFAMILY SSF55486 10 492 4.52E-83 T 15-10-2018 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 399 420 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 289 305 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 444 462 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 225 241 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 242 261 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 262 281 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 376 393 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 330 349 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 145 165 3.5E-48 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_00805 19983efcc2fdb3aa9fcb9b7a7678b103 498 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 13 492 5.6E-119 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_12185 c84963761dccd0fd2d9fb201bc6f94d3 312 SUPERFAMILY SSF52172 2 130 6.12E-22 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_12185 c84963761dccd0fd2d9fb201bc6f94d3 312 Pfam PF00072 Response regulator receiver domain 4 114 5.6E-19 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12185 c84963761dccd0fd2d9fb201bc6f94d3 312 Pfam PF08664 YcbB domain 161 296 5.0E-50 T 15-10-2018 IPR013972 YcbB domain C2I28_12185 c84963761dccd0fd2d9fb201bc6f94d3 312 Gene3D G3DSA:3.40.50.2300 1 129 9.7E-22 T 15-10-2018 C2I28_12185 c84963761dccd0fd2d9fb201bc6f94d3 312 SMART SM00448 1 114 1.4E-18 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 166 5.1E-54 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 Pfam PF00364 Biotin-requiring enzyme 92 163 1.8E-23 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 SUPERFAMILY SSF51230 90 165 3.8E-23 T 15-10-2018 IPR011053 Single hybrid motif C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 127 140 1.3E-15 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 108 1.3E-15 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 126 1.3E-15 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_03870 6bfc427754b50dba07016ba7253813f4 168 Gene3D G3DSA:2.40.50.100 88 165 2.1E-28 T 15-10-2018 C2I28_26465 f8a591504c0d1f3b832383b9d53be96c 191 Pfam PF03079 ARD/ARD' family 58 180 2.5E-14 T 15-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I28_26465 f8a591504c0d1f3b832383b9d53be96c 191 SUPERFAMILY SSF51182 78 181 8.47E-17 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_26465 f8a591504c0d1f3b832383b9d53be96c 191 Gene3D G3DSA:2.60.120.10 15 183 2.1E-30 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_08800 b5600766d53af32e0bc74e7ea861ce75 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.211 T 15-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 C2I28_08800 b5600766d53af32e0bc74e7ea861ce75 72 SMART SM00316 4 72 3.1E-6 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_08800 b5600766d53af32e0bc74e7ea861ce75 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 2.0E-39 T 15-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 C2I28_08800 b5600766d53af32e0bc74e7ea861ce75 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 6.7E-29 T 15-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 C2I28_08800 b5600766d53af32e0bc74e7ea861ce75 72 Gene3D G3DSA:2.40.50.140 1 72 3.6E-38 T 15-10-2018 C2I28_08800 b5600766d53af32e0bc74e7ea861ce75 72 SUPERFAMILY SSF50249 1 71 1.4E-28 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_23255 ee74ed9358da922554ec79db6e586369 144 Pfam PF00571 CBS domain 9 59 2.0E-9 T 15-10-2018 IPR000644 CBS domain C2I28_23255 ee74ed9358da922554ec79db6e586369 144 Pfam PF00571 CBS domain 88 127 0.0017 T 15-10-2018 IPR000644 CBS domain C2I28_23255 ee74ed9358da922554ec79db6e586369 144 SMART SM00116 12 60 4.3E-6 T 15-10-2018 IPR000644 CBS domain C2I28_23255 ee74ed9358da922554ec79db6e586369 144 Gene3D G3DSA:3.10.580.10 1 143 4.2E-45 T 15-10-2018 C2I28_23255 ee74ed9358da922554ec79db6e586369 144 SUPERFAMILY SSF54631 3 130 2.53E-28 T 15-10-2018 C2I28_06280 321fc03d8a4ce83464c619d2f8780acf 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_06280 321fc03d8a4ce83464c619d2f8780acf 387 Gene3D G3DSA:1.20.1090.10 185 386 2.2E-47 T 15-10-2018 C2I28_06280 321fc03d8a4ce83464c619d2f8780acf 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 369 4.2E-100 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_06280 321fc03d8a4ce83464c619d2f8780acf 387 SUPERFAMILY SSF56796 2 385 4.45E-117 T 15-10-2018 C2I28_06280 321fc03d8a4ce83464c619d2f8780acf 387 Gene3D G3DSA:3.40.50.1970 1 184 1.8E-56 T 15-10-2018 C2I28_06280 321fc03d8a4ce83464c619d2f8780acf 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 SUPERFAMILY SSF52317 291 530 3.77E-85 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 53.224 T 15-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 Pfam PF06418 CTP synthase N-terminus 3 267 1.6E-130 T 15-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 4.1E-267 T 15-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 Gene3D G3DSA:3.40.50.880 288 535 8.9E-104 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 SUPERFAMILY SSF52540 1 270 9.11E-128 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 Pfam PF00117 Glutamine amidotransferase class-I 302 526 3.2E-59 T 15-10-2018 IPR017926 Glutamine amidotransferase C2I28_07465 fd674cf4e132ceac45e29bbade020836 535 Gene3D G3DSA:3.40.50.300 1 286 1.1E-136 T 15-10-2018 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SUPERFAMILY SSF52540 367 606 5.2E-68 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SUPERFAMILY SSF55785 217 336 3.66E-15 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SUPERFAMILY SSF55785 104 215 2.62E-17 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Pfam PF00158 Sigma-54 interaction domain 368 536 2.4E-66 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Gene3D G3DSA:3.40.50.300 355 539 7.5E-64 T 15-10-2018 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Gene3D G3DSA:1.10.10.60 627 686 1.2E-13 T 15-10-2018 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 117 221 2.0E-10 T 15-10-2018 IPR000014 PAS domain C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 233 349 4.1E-16 T 15-10-2018 IPR000014 PAS domain C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Gene3D G3DSA:1.10.8.60 540 618 1.6E-21 T 15-10-2018 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Pfam PF02954 Bacterial regulatory protein, Fis family 642 681 6.7E-11 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SMART SM00382 388 532 3.0E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SUPERFAMILY SSF51735 1 131 3.88E-11 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Gene3D G3DSA:3.30.450.20 104 219 2.0E-20 T 15-10-2018 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Gene3D G3DSA:3.30.450.20 223 339 8.9E-18 T 15-10-2018 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Pfam PF00989 PAS fold 237 339 2.4E-13 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 Pfam PF00989 PAS fold 118 218 2.9E-12 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SUPERFAMILY SSF46689 582 683 3.58E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 664 684 1.0E-6 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 647 664 1.0E-6 T 15-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SMART SM00091 117 184 5.0E-9 T 15-10-2018 IPR000014 PAS domain C2I28_03785 83744ca86b99cfbe3311eef45fc26c45 689 SMART SM00091 236 301 2.0E-6 T 15-10-2018 IPR000014 PAS domain C2I28_07215 911a99aa2f2c5b743594c2063c239cb9 235 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 54 228 8.1E-58 T 15-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 C2I28_07215 911a99aa2f2c5b743594c2063c239cb9 235 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 58 222 1.2E-60 T 15-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 C2I28_07215 911a99aa2f2c5b743594c2063c239cb9 235 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 1 235 58.11 T 15-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 6.1E-19 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 Gene3D G3DSA:1.20.120.530 95 225 1.7E-25 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 SUPERFAMILY SSF48008 98 223 4.18E-25 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 Gene3D G3DSA:1.10.10.10 5 80 2.4E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 7.9E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 7.9E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 SMART SM00345 21 80 7.5E-18 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 SMART SM00895 101 225 7.0E-20 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 Pfam PF07729 FCD domain 102 219 1.8E-22 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_24960 63f0cf6522cd2a1f992fc226c36959bc 226 SUPERFAMILY SSF46785 11 84 1.04E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_14430 eaa29cace35e9c0d5d8171df459a940e 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 72.567 T 15-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I28_14430 eaa29cace35e9c0d5d8171df459a940e 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 138 2.7E-56 T 15-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I28_14430 eaa29cace35e9c0d5d8171df459a940e 165 SUPERFAMILY SSF55620 27 136 4.45E-29 T 15-10-2018 C2I28_14430 eaa29cace35e9c0d5d8171df459a940e 165 Pfam PF14489 QueF-like protein 62 140 1.9E-35 T 15-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I28_14430 eaa29cace35e9c0d5d8171df459a940e 165 Gene3D G3DSA:3.30.1130.10 21 165 5.4E-69 T 15-10-2018 C2I28_14430 eaa29cace35e9c0d5d8171df459a940e 165 PIRSF PIRSF027377 10 147 1.1E-62 T 15-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 C2I28_12760 f9b0e25ea5120b136447bb74c06ebfa3 241 Pfam PF01380 SIS domain 106 230 5.2E-15 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_12760 f9b0e25ea5120b136447bb74c06ebfa3 241 Gene3D G3DSA:3.40.50.10490 82 241 3.4E-28 T 15-10-2018 C2I28_12760 f9b0e25ea5120b136447bb74c06ebfa3 241 SUPERFAMILY SSF53697 84 237 1.0E-23 T 15-10-2018 C2I28_12760 f9b0e25ea5120b136447bb74c06ebfa3 241 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 76 8.1E-16 T 15-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I28_12760 f9b0e25ea5120b136447bb74c06ebfa3 241 Gene3D G3DSA:1.10.10.10 4 76 1.7E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12760 f9b0e25ea5120b136447bb74c06ebfa3 241 SUPERFAMILY SSF46689 5 76 8.6E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_13785 261981ea2cd898ea873307d863140597 316 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 92 233 1.7E-50 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_13785 261981ea2cd898ea873307d863140597 316 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 91 234 1.4E-53 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_13785 261981ea2cd898ea873307d863140597 316 Gene3D G3DSA:1.10.260.150 57 316 6.6E-91 T 15-10-2018 C2I28_13785 261981ea2cd898ea873307d863140597 316 Hamap MF_01140 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU [tagU]. 16 315 51.867 T 15-10-2018 IPR023734 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU C2I28_10415 fd026a94b51756ab851fff7273364617 343 Pfam PF01594 AI-2E family transporter 9 330 4.0E-51 T 15-10-2018 IPR002549 Transmembrane protein TqsA-like C2I28_10415 fd026a94b51756ab851fff7273364617 343 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 8 337 9.5E-94 T 15-10-2018 IPR014227 Putative transport protein YtvI-like C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 Pfam PF08864 UPF0302 domain 9 113 1.1E-46 T 15-10-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 Hamap MF_00760 UPF0302 protein . 2 178 31.544 T 15-10-2018 IPR011188 Uncharacterised protein family UPF0302 C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 Pfam PF08858 IDEAL domain 139 173 1.8E-13 T 15-10-2018 IPR014957 IDEAL domain C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 SMART SM00914 139 175 1.1E-11 T 15-10-2018 IPR014957 IDEAL domain C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 Gene3D G3DSA:1.20.1440.290 1 123 1.3E-55 T 15-10-2018 IPR038091 UPF0302, N-terminal domain superfamily C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 PIRSF PIRSF007165 1 180 5.5E-78 T 15-10-2018 IPR011188 Uncharacterised protein family UPF0302 C2I28_03140 1b46b2b7e8bf31ef99e1d21b0a75e0b2 181 Gene3D G3DSA:4.10.810.10 124 180 4.9E-17 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_13770 13f4e262c6911ad2ac4433dc3d4b9cfd 268 Pfam PF01061 ABC-2 type transporter 19 226 8.7E-21 T 15-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 327 2.1E-151 T 15-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 SUPERFAMILY SSF46785 257 331 5.71E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04765 0a52a61477f0800e51bb861924c20272 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 331 3.0E-36 T 15-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 6 236 2.7E-119 T 15-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 1.3E-33 T 15-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 175.11 T 15-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 Gene3D G3DSA:3.40.50.300 19 182 1.2E-40 T 15-10-2018 C2I28_04765 0a52a61477f0800e51bb861924c20272 333 SMART SM00382 52 179 5.1E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04765 0a52a61477f0800e51bb861924c20272 333 SUPERFAMILY SSF52540 21 255 2.41E-56 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04765 0a52a61477f0800e51bb861924c20272 333 Gene3D G3DSA:1.10.10.10 258 333 1.1E-31 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04765 0a52a61477f0800e51bb861924c20272 333 Gene3D G3DSA:1.10.8.60 183 257 4.8E-32 T 15-10-2018 C2I28_13800 f0756b815e7b05945207352d9ba2d4aa 255 PIRSF PIRSF016557 1 254 4.7E-58 T 15-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 C2I28_13800 f0756b815e7b05945207352d9ba2d4aa 255 Gene3D G3DSA:3.20.20.140 1 255 3.8E-60 T 15-10-2018 C2I28_19865 5dc9228ff7de4e4ee48e850e675e0bd3 247 Gene3D G3DSA:3.90.1560.10 1 238 1.2E-73 T 15-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 C2I28_19865 5dc9228ff7de4e4ee48e850e675e0bd3 247 SUPERFAMILY SSF142823 4 236 3.01E-58 T 15-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 C2I28_19865 5dc9228ff7de4e4ee48e850e675e0bd3 247 Pfam PF04029 2-phosphosulpholactate phosphatase 11 233 5.7E-65 T 15-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 C2I28_27460 86ffadfe37959ce5a06980b3fcc4a86c 305 Gene3D G3DSA:3.40.50.720 4 234 1.4E-104 T 15-10-2018 C2I28_27460 86ffadfe37959ce5a06980b3fcc4a86c 305 SUPERFAMILY SSF51735 1 303 5.08E-91 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_27460 86ffadfe37959ce5a06980b3fcc4a86c 305 Gene3D G3DSA:3.90.25.10 172 298 1.4E-104 T 15-10-2018 C2I28_27460 86ffadfe37959ce5a06980b3fcc4a86c 305 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 297 5.5E-63 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 5.9E-17 T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 5.9E-17 T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 5.9E-17 T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 TIGRFAM TIGR00077 lspA: signal peptidase II 1 151 1.2E-45 T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 Pfam PF01252 Signal peptidase (SPase) II 6 145 3.5E-39 T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02870 9a68f48b8c2a36f1725825b88e75d10b 155 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 150 16.722 T 15-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 C2I28_02965 ad5e749a6f83ef696cd8002b5283d818 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 324 1.7E-121 T 15-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02965 ad5e749a6f83ef696cd8002b5283d818 324 Pfam PF00953 Glycosyl transferase family 4 83 248 1.2E-40 T 15-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 C2I28_02965 ad5e749a6f83ef696cd8002b5283d818 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 15-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02965 ad5e749a6f83ef696cd8002b5283d818 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.4E-5 T 15-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02965 ad5e749a6f83ef696cd8002b5283d818 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 25.114 T 15-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02965 ad5e749a6f83ef696cd8002b5283d818 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 15-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 SUPERFAMILY SSF52540 3 304 4.09E-89 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 SUPERFAMILY SSF81271 282 363 1.94E-35 T 15-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 Gene3D G3DSA:3.40.50.300 4 281 9.9E-159 T 15-10-2018 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 Gene3D G3DSA:1.10.150.300 113 200 9.9E-159 T 15-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.761 T 15-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 Pfam PF01926 50S ribosome-binding GTPase 5 124 1.7E-24 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 6.9E-161 T 15-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 PIRSF PIRSF006641 1 366 3.3E-166 T 15-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.6E-36 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.6E-36 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.6E-36 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.6E-36 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 Gene3D G3DSA:3.10.20.30 48 364 9.9E-159 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_07940 b198d42f2b24da8c987cba7c480a809d 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 1.9E-39 T 15-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 157 361 9.5E-19 T 15-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 SMART SM00959 7 49 3.3E-17 T 15-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Pfam PF07497 Rho termination factor, RNA-binding domain 53 126 2.1E-31 T 15-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Gene3D G3DSA:1.10.720.10 1 47 4.0E-20 T 15-10-2018 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 222.327 T 15-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 SMART SM00357 54 119 7.8E-20 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 413 1.1E-203 T 15-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Pfam PF07498 Rho termination factor, N-terminal domain 8 49 3.9E-16 T 15-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 SUPERFAMILY SSF50249 51 126 4.28E-24 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Gene3D G3DSA:3.40.50.300 131 419 1.1E-123 T 15-10-2018 C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 SMART SM00382 168 353 4.2E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 SUPERFAMILY SSF52540 91 369 1.56E-68 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 SUPERFAMILY SSF68912 4 49 3.61E-11 T 15-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily C2I28_07435 3d5e76c2f2973cafaad9954f12984aff 424 Gene3D G3DSA:2.40.50.140 48 124 4.7E-29 T 15-10-2018 C2I28_01285 630fedd5e2a902ad5665d4bf4846fc70 165 SUPERFAMILY SSF55729 2 159 3.88E-27 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01285 630fedd5e2a902ad5665d4bf4846fc70 165 Gene3D G3DSA:3.40.630.30 1 148 1.7E-26 T 15-10-2018 C2I28_01285 630fedd5e2a902ad5665d4bf4846fc70 165 Pfam PF00583 Acetyltransferase (GNAT) family 33 142 3.4E-17 T 15-10-2018 IPR000182 GNAT domain C2I28_09660 3942cec25412ed4b0055dfc588fcec0f 191 Gene3D G3DSA:3.10.450.40 24 96 5.2E-6 T 15-10-2018 C2I28_09660 3942cec25412ed4b0055dfc588fcec0f 191 Gene3D G3DSA:3.10.450.40 122 190 1.2E-14 T 15-10-2018 C2I28_09660 3942cec25412ed4b0055dfc588fcec0f 191 Pfam PF03413 Peptidase propeptide and YPEB domain 127 181 1.1E-9 T 15-10-2018 IPR025711 PepSY domain C2I28_09660 3942cec25412ed4b0055dfc588fcec0f 191 Pfam PF03413 Peptidase propeptide and YPEB domain 32 87 0.0039 T 15-10-2018 IPR025711 PepSY domain C2I28_17520 001e0658e5fd9ce317990f60d4bad4b6 185 Pfam PF07563 Protein of unknown function (DUF1541) 128 179 1.5E-30 T 15-10-2018 IPR011438 Domain of unknown function DUF1541 C2I28_17520 001e0658e5fd9ce317990f60d4bad4b6 185 Pfam PF07563 Protein of unknown function (DUF1541) 64 115 1.9E-27 T 15-10-2018 IPR011438 Domain of unknown function DUF1541 C2I28_17520 001e0658e5fd9ce317990f60d4bad4b6 185 Gene3D G3DSA:2.30.30.1210 39 185 1.7E-72 T 15-10-2018 C2I28_05015 5fbd066ebb2a916f1c06724e195bb755 333 SUPERFAMILY SSF116965 78 290 3.01E-14 T 15-10-2018 C2I28_05015 5fbd066ebb2a916f1c06724e195bb755 333 Gene3D G3DSA:1.25.40.10 15 97 9.5E-15 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_05015 5fbd066ebb2a916f1c06724e195bb755 333 Pfam PF14559 Tetratricopeptide repeat 27 89 1.9E-10 T 15-10-2018 C2I28_05015 5fbd066ebb2a916f1c06724e195bb755 333 SUPERFAMILY SSF48452 13 109 1.77E-9 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_03560 c9d1b3c2601b48fa1c3e93a875eb1ef1 150 Gene3D G3DSA:1.10.10.10 1 88 1.9E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03560 c9d1b3c2601b48fa1c3e93a875eb1ef1 150 SUPERFAMILY SSF46785 6 141 1.09E-39 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_03560 c9d1b3c2601b48fa1c3e93a875eb1ef1 150 Gene3D G3DSA:3.30.1490.190 93 150 2.4E-17 T 15-10-2018 C2I28_03560 c9d1b3c2601b48fa1c3e93a875eb1ef1 150 Pfam PF01475 Ferric uptake regulator family 15 136 4.6E-41 T 15-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 C2I28_18625 23e0410fc12d67286fefffdfb0ede78c 214 SUPERFAMILY SSF51391 8 211 5.75E-67 T 15-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18625 23e0410fc12d67286fefffdfb0ede78c 214 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 213 28.092 T 15-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18625 23e0410fc12d67286fefffdfb0ede78c 214 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 11 208 1.8E-66 T 15-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18625 23e0410fc12d67286fefffdfb0ede78c 214 Pfam PF02581 Thiamine monophosphate synthase 12 195 3.3E-61 T 15-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18625 23e0410fc12d67286fefffdfb0ede78c 214 Gene3D G3DSA:3.20.20.70 1 214 4.0E-76 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_17680 abe25546189e9c0cf876dd2d719ed54a 231 Gene3D G3DSA:1.10.101.10 149 230 1.1E-22 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_17680 abe25546189e9c0cf876dd2d719ed54a 231 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 70 133 3.1E-18 T 15-10-2018 IPR039561 Peptidase M15C GO:0008233 C2I28_17680 abe25546189e9c0cf876dd2d719ed54a 231 SUPERFAMILY SSF47090 156 223 7.59E-21 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_17680 abe25546189e9c0cf876dd2d719ed54a 231 Gene3D G3DSA:3.30.1380.10 6 132 4.7E-41 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_17680 abe25546189e9c0cf876dd2d719ed54a 231 SUPERFAMILY SSF55166 15 133 1.41E-32 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_17680 abe25546189e9c0cf876dd2d719ed54a 231 Pfam PF01471 Putative peptidoglycan binding domain 165 222 1.6E-18 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_26755 b6d7c047e47e9c3cb42b00d32dd2732e 251 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 9 245 1.9E-113 T 15-10-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I28_26755 b6d7c047e47e9c3cb42b00d32dd2732e 251 Pfam PF07071 KDGP aldolase 9 227 3.0E-102 T 15-10-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I28_26755 b6d7c047e47e9c3cb42b00d32dd2732e 251 Gene3D G3DSA:3.20.20.70 1 251 4.8E-111 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 Gene3D G3DSA:3.90.1150.10 9 423 6.2E-170 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 Gene3D G3DSA:3.40.640.10 72 320 6.2E-170 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 Pfam PF00202 Aminotransferase class-III 36 403 2.2E-72 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 SUPERFAMILY SSF53383 2 428 1.75E-124 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 94.309 T 15-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I28_10130 405f8e9696bb087829fb0ad6968dacf8 432 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 427 2.7E-171 T 15-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I28_17400 935ae7c9b1d9e42a379417115eed8470 374 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 209 362 7.3E-21 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_17400 935ae7c9b1d9e42a379417115eed8470 374 Gene3D G3DSA:3.30.300.210 223 366 7.5E-14 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_17400 935ae7c9b1d9e42a379417115eed8470 374 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 363 1.9E-63 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 Gene3D G3DSA:3.20.20.10 24 245 5.0E-132 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 Pfam PF00842 Alanine racemase, C-terminal domain 258 381 4.7E-46 T 15-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 SUPERFAMILY SSF51419 22 249 2.47E-62 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 Pfam PF01168 Alanine racemase, N-terminal domain 22 242 1.0E-64 T 15-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 Hamap MF_01201 Alanine racemase. 15 382 34.882 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 TIGRFAM TIGR00492 alr: alanine racemase 16 382 2.4E-126 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 215 242 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 137 149 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 290 305 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 172 183 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 77 95 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 310 327 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 41 57 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 364 377 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 PRINTS PR00992 Alanine racemase signature 273 288 3.5E-69 T 15-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 46 56 - T 15-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 SUPERFAMILY SSF50621 252 393 1.15E-51 T 15-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 SMART SM01005 257 382 8.4E-70 T 15-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 C2I28_09140 d6ed0c7c7d102179c6085604f9d222c0 396 Gene3D G3DSA:2.40.37.10 19 381 5.0E-132 T 15-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 SUPERFAMILY SSF69189 271 368 1.82E-21 T 15-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 279 369 1.8E-22 T 15-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 259 6.4E-86 T 15-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 SMART SM00936 279 370 3.8E-29 T 15-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 1.7E-17 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 62 73 1.7E-17 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 132 1.7E-17 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 SUPERFAMILY SSF56601 1 279 3.52E-81 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 Gene3D G3DSA:3.40.710.10 18 278 2.4E-91 T 15-10-2018 C2I28_03535 7764e8915dbe5c6e7127b881bec25892 388 Gene3D G3DSA:2.60.410.10 279 369 2.3E-24 T 15-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_03505 c1da01f599c697e87dd27af0078533d2 153 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 10 148 1.7E-64 T 15-10-2018 IPR014203 Sporulation stage V, protein AC C2I28_03505 c1da01f599c697e87dd27af0078533d2 153 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 27 144 4.6E-41 T 15-10-2018 IPR005562 SpoVA C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Pfam PF00672 HAMP domain 197 243 2.7E-11 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Pfam PF00512 His Kinase A (phospho-acceptor) domain 366 433 1.4E-19 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Gene3D G3DSA:1.20.1480.50 159 254 3.2E-19 T 15-10-2018 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SUPERFAMILY SSF158472 197 244 4.05E-10 T 15-10-2018 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Gene3D G3DSA:3.30.450.20 257 358 1.7E-11 T 15-10-2018 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SMART SM00388 366 433 3.1E-21 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SMART SM00304 196 248 8.8E-13 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SUPERFAMILY SSF55785 243 358 5.52E-9 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 589 3.3E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 552 570 1.9E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 545 1.9E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 531 1.9E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 576 589 1.9E-19 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SUPERFAMILY SSF47384 350 434 1.06E-20 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SMART SM00387 480 590 1.5E-36 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 SUPERFAMILY SSF55874 422 590 2.23E-47 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Gene3D G3DSA:3.30.565.10 438 590 2.8E-48 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Gene3D G3DSA:1.10.287.130 359 437 1.2E-24 T 15-10-2018 C2I28_03400 7c21db5a8a3102405c886b2b71ad9cfa 590 Pfam PF00989 PAS fold 255 357 2.7E-5 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_19750 b723f0956578753107290dfaffb4b2a9 426 Pfam PF02447 GntP family permease 5 418 1.9E-10 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_04470 279246105b058fa07685427c8b396d07 99 SMART SM01103 2 85 8.0E-45 T 15-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 C2I28_04470 279246105b058fa07685427c8b396d07 99 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 2.0E-40 T 15-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 C2I28_04470 279246105b058fa07685427c8b396d07 99 Gene3D G3DSA:3.30.110.60 1 99 5.7E-38 T 15-10-2018 IPR035920 YhbY-like superfamily C2I28_04470 279246105b058fa07685427c8b396d07 99 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 1.6E-22 T 15-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 C2I28_04470 279246105b058fa07685427c8b396d07 99 SUPERFAMILY SSF75471 1 94 8.24E-32 T 15-10-2018 IPR035920 YhbY-like superfamily C2I28_04470 279246105b058fa07685427c8b396d07 99 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 4.0E-36 T 15-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 SMART SM00839 195 424 9.5E-94 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 Gene3D G3DSA:1.10.8.1210 379 426 2.5E-17 T 15-10-2018 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 SUPERFAMILY SSF51735 193 425 1.24E-77 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 112 125 - T 15-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 PIRSF PIRSF000185 11 426 8.8E-172 T 15-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 SUPERFAMILY SSF53223 17 195 1.95E-65 T 15-10-2018 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 48 175 6.7E-53 T 15-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 Gene3D G3DSA:3.40.50.720 181 353 2.3E-143 T 15-10-2018 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 Gene3D G3DSA:3.40.50.10860 45 180 2.3E-143 T 15-10-2018 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 193 424 9.1E-78 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 Gene3D G3DSA:1.10.8.1210 20 354 2.3E-143 T 15-10-2018 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 226 246 3.7E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 104 118 3.7E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 184 206 3.7E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03335 20ccb3b6542231f73cd0ce8d514828dd 426 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 352 363 3.7E-30 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_16175 0ac878560727adc34e65bd3445324e38 277 ProSitePatterns PS00801 Transketolase signature 1. 17 37 - T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_16175 0ac878560727adc34e65bd3445324e38 277 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 268 3.4E-59 T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_16175 0ac878560727adc34e65bd3445324e38 277 Gene3D G3DSA:3.40.50.970 1 274 6.2E-105 T 15-10-2018 C2I28_16175 0ac878560727adc34e65bd3445324e38 277 SUPERFAMILY SSF52518 13 270 7.04E-84 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_22345 bc6bddc74fc7c6e606a624f267fa1dcc 256 Pfam PF00005 ABC transporter 22 180 2.1E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_22345 bc6bddc74fc7c6e606a624f267fa1dcc 256 Gene3D G3DSA:3.40.50.300 4 256 1.5E-71 T 15-10-2018 C2I28_22345 bc6bddc74fc7c6e606a624f267fa1dcc 256 SMART SM00382 31 229 6.8E-15 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_22345 bc6bddc74fc7c6e606a624f267fa1dcc 256 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_22345 bc6bddc74fc7c6e606a624f267fa1dcc 256 SUPERFAMILY SSF52540 6 251 2.61E-63 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12180 e277dc835057b808f7da81f42c9c6df4 202 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 5 197 4.7E-40 T 15-10-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 C2I28_12180 e277dc835057b808f7da81f42c9c6df4 202 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 5 197 3.9E-43 T 15-10-2018 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 PRINTS PR00340 P-II protein signature 83 103 4.8E-34 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 PRINTS PR00340 P-II protein signature 52 75 4.8E-34 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 PRINTS PR00340 P-II protein signature 23 41 4.8E-34 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 PRINTS PR00340 P-II protein signature 2 17 4.8E-34 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.6E-34 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 Gene3D G3DSA:3.30.70.120 1 112 4.6E-42 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 15-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 SUPERFAMILY SSF54913 1 112 8.58E-37 T 15-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta C2I28_11450 bc78dc8f16721c5cfda398b84755668a 113 SMART SM00938 4 105 1.4E-43 T 15-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 C2I28_23820 dad1eb778147bcdddb300d5741ef4ef6 547 PIRSF PIRSF006060 1 453 5.0E-74 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_23820 dad1eb778147bcdddb300d5741ef4ef6 547 PIRSF PIRSF006060 444 535 0.084 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_23820 dad1eb778147bcdddb300d5741ef4ef6 547 Pfam PF13520 Amino acid permease 9 420 4.1E-47 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_23820 dad1eb778147bcdddb300d5741ef4ef6 547 Gene3D G3DSA:1.20.1740.10 1 459 5.9E-78 T 15-10-2018 C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 30.28 T 15-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 Gene3D G3DSA:2.40.50.140 2 81 5.8E-12 T 15-10-2018 C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 243 7.6E-81 T 15-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 Gene3D G3DSA:1.20.1440.120 88 225 2.3E-19 T 15-10-2018 C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 Pfam PF11967 Recombination protein O N terminal 4 77 1.2E-23 T 15-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 SUPERFAMILY SSF57863 81 231 3.92E-48 T 15-10-2018 IPR037278 ARFGAP/RecO-like zinc finger C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 SUPERFAMILY SSF50249 4 77 1.3E-18 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 Pfam PF02565 Recombination protein O C terminal 82 237 7.5E-42 T 15-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 C2I28_04285 aeee9af399cd14e28c1068125cbf3a5a 254 Gene3D G3DSA:3.30.60.100 146 181 2.3E-19 T 15-10-2018 C2I28_25215 a4f00f7c0982e4a4f2515f20acf9e5ba 241 SUPERFAMILY SSF52540 3 230 5.65E-64 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_25215 a4f00f7c0982e4a4f2515f20acf9e5ba 241 SMART SM00382 30 215 5.7E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_25215 a4f00f7c0982e4a4f2515f20acf9e5ba 241 Gene3D G3DSA:3.40.50.300 3 239 6.8E-65 T 15-10-2018 C2I28_25215 a4f00f7c0982e4a4f2515f20acf9e5ba 241 Pfam PF00005 ABC transporter 22 166 3.4E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_25215 a4f00f7c0982e4a4f2515f20acf9e5ba 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 SUPERFAMILY SSF143724 125 324 3.14E-56 T 15-10-2018 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Pfam PF13089 Polyphosphate kinase N-terminal domain 20 127 5.9E-40 T 15-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 SUPERFAMILY SSF140356 17 121 4.45E-38 T 15-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 SUPERFAMILY SSF56024 521 701 6.5E-69 T 15-10-2018 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 PIRSF PIRSF015589 2 707 1.5E-274 T 15-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Pfam PF13090 Polyphosphate kinase C-terminal domain 351 698 7.3E-153 T 15-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Pfam PF02503 Polyphosphate kinase middle domain 138 341 8.4E-67 T 15-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 SUPERFAMILY SSF56024 337 517 3.92E-56 T 15-10-2018 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Gene3D G3DSA:3.30.1840.10 12 330 1.2E-108 T 15-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Gene3D G3DSA:3.30.870.10 338 520 6.9E-75 T 15-10-2018 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Gene3D G3DSA:3.30.870.10 521 706 6.7E-69 T 15-10-2018 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 19 699 4.0E-271 T 15-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 C2I28_14640 55541b49fed9a0713e9a2b9a3916b26a 707 Hamap MF_00347 Polyphosphate kinase [ppk]. 17 703 28.497 T 15-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Gene3D G3DSA:1.10.1750.10 346 446 2.3E-35 T 15-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 SUPERFAMILY SSF52540 112 323 4.88E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08015 4f401b49d819521986f9d79926a259fa 447 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 444 4.4E-190 T 15-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 SMART SM00760 355 424 2.0E-41 T 15-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 SMART SM00382 143 271 5.8E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08015 4f401b49d819521986f9d79926a259fa 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 15-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I28_08015 4f401b49d819521986f9d79926a259fa 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 15-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I28_08015 4f401b49d819521986f9d79926a259fa 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 15-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I28_08015 4f401b49d819521986f9d79926a259fa 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 15-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I28_08015 4f401b49d819521986f9d79926a259fa 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 15-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.218 T 15-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Gene3D G3DSA:3.40.50.300 95 275 7.2E-55 T 15-10-2018 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 SUPERFAMILY SSF48295 342 445 1.49E-36 T 15-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Pfam PF00308 Bacterial dnaA protein 111 327 6.4E-107 T 15-10-2018 IPR013317 Chromosomal replication initiator protein DnaA C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Gene3D G3DSA:3.30.300.180 1 81 1.9E-32 T 15-10-2018 IPR038454 DnaA, N-terminal domain superfamily C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Gene3D G3DSA:1.10.8.60 277 345 1.6E-29 T 15-10-2018 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 424 1.6E-30 T 15-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 15-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 C2I28_08015 4f401b49d819521986f9d79926a259fa 447 Pfam PF11638 DnaA N-terminal domain 6 66 1.2E-18 T 15-10-2018 IPR024633 DnaA N-terminal domain C2I28_20645 57a01ec37d3585dd8f23dbd3118a1b45 262 Pfam PF14024 Protein of unknown function (DUF4240) 80 206 1.7E-37 T 15-10-2018 IPR025334 Domain of unknown function (DUF4240 C2I28_20645 57a01ec37d3585dd8f23dbd3118a1b45 262 Gene3D G3DSA:2.20.140.10 2 72 7.2E-25 T 15-10-2018 IPR036930 WGR domain superfamily C2I28_20645 57a01ec37d3585dd8f23dbd3118a1b45 262 SUPERFAMILY SSF142921 11 68 4.97E-6 T 15-10-2018 IPR036930 WGR domain superfamily C2I28_20645 57a01ec37d3585dd8f23dbd3118a1b45 262 SMART SM00773 1 71 8.1E-13 T 15-10-2018 IPR008893 WGR domain C2I28_20645 57a01ec37d3585dd8f23dbd3118a1b45 262 Pfam PF05406 WGR domain 4 67 3.7E-13 T 15-10-2018 IPR008893 WGR domain C2I28_25860 b0fe4d0fd9ea7ce3d909db41a5b2794b 277 SUPERFAMILY SSF47413 31 85 5.3E-6 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_25860 b0fe4d0fd9ea7ce3d909db41a5b2794b 277 Gene3D G3DSA:3.30.450.180 109 275 4.0E-18 T 15-10-2018 C2I28_25860 b0fe4d0fd9ea7ce3d909db41a5b2794b 277 Pfam PF13560 Helix-turn-helix domain 10 89 1.5E-15 T 15-10-2018 C2I28_25860 b0fe4d0fd9ea7ce3d909db41a5b2794b 277 Gene3D G3DSA:1.10.260.40 16 82 5.5E-6 T 15-10-2018 C2I28_25860 b0fe4d0fd9ea7ce3d909db41a5b2794b 277 SMART SM00530 14 86 2.5E-4 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_05975 6754d3c358e10c1f2b84026536223376 347 SUPERFAMILY SSF47240 21 347 6.45E-82 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_05975 6754d3c358e10c1f2b84026536223376 347 PIRSF PIRSF000355 1 347 2.4E-118 T 15-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_05975 6754d3c358e10c1f2b84026536223376 347 Gene3D G3DSA:1.10.620.20 24 314 1.5E-87 T 15-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 C2I28_05975 6754d3c358e10c1f2b84026536223376 347 Pfam PF00268 Ribonucleotide reductase, small chain 31 304 1.0E-67 T 15-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Gene3D G3DSA:3.40.50.300 6 191 6.2E-40 T 15-10-2018 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Gene3D G3DSA:3.40.50.300 280 478 3.7E-32 T 15-10-2018 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1066 1234 1.1E-8 T 15-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Pfam PF13361 UvrD-like helicase C-terminal domain 476 894 6.1E-37 T 15-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 SUPERFAMILY SSF52980 1025 1242 3.49E-40 T 15-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Gene3D G3DSA:3.90.320.10 1003 1245 4.4E-80 T 15-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Gene3D G3DSA:3.40.50.300 768 971 4.5E-50 T 15-10-2018 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Gene3D G3DSA:3.40.50.300 479 767 1.1E-58 T 15-10-2018 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 SUPERFAMILY SSF52540 10 899 1.6E-121 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 465 4.7E-89 T 15-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 11 1245 19.976 T 15-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 C2I28_11365 f35a5c477fbe2c0175d60a9860437044 1245 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 13 1244 0.0 T 15-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 C2I28_11670 ed3889ec0347ed2dc7e09f4f38abf893 579 Gene3D G3DSA:3.40.190.10 25 309 1.0E-65 T 15-10-2018 C2I28_11670 ed3889ec0347ed2dc7e09f4f38abf893 579 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 496 2.6E-85 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_11670 ed3889ec0347ed2dc7e09f4f38abf893 579 SUPERFAMILY SSF53850 51 577 1.7E-120 T 15-10-2018 C2I28_11670 ed3889ec0347ed2dc7e09f4f38abf893 579 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 104 125 - T 15-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I28_11670 ed3889ec0347ed2dc7e09f4f38abf893 579 Gene3D G3DSA:3.10.105.10 310 545 7.8E-65 T 15-10-2018 C2I28_11670 ed3889ec0347ed2dc7e09f4f38abf893 579 PIRSF PIRSF002741 4 579 1.6E-108 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_08855 532826cd3d8000102837898ce68be357 130 SUPERFAMILY SSF54211 5 130 1.86E-49 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08855 532826cd3d8000102837898ce68be357 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.085 T 15-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid C2I28_08855 532826cd3d8000102837898ce68be357 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 15-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 C2I28_08855 532826cd3d8000102837898ce68be357 130 Gene3D G3DSA:3.30.230.10 1 130 3.1E-53 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_08855 532826cd3d8000102837898ce68be357 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 6.7E-47 T 15-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 C2I28_12690 6a9a11317c5a7e361f20a8dea97a5390 109 Pfam PF01638 HxlR-like helix-turn-helix 16 102 7.8E-39 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_12690 6a9a11317c5a7e361f20a8dea97a5390 109 SMART SM00418 12 92 0.0061 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_12690 6a9a11317c5a7e361f20a8dea97a5390 109 Gene3D G3DSA:1.10.10.10 2 108 6.0E-40 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12690 6a9a11317c5a7e361f20a8dea97a5390 109 SUPERFAMILY SSF46785 3 104 1.48E-34 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 29.993 T 15-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 305 1.1E-47 T 15-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 Gene3D G3DSA:3.30.460.30 1 158 1.5E-54 T 15-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 SUPERFAMILY SSF51735 162 315 2.59E-40 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 SUPERFAMILY SSF69742 1 158 3.66E-47 T 15-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 Gene3D G3DSA:3.40.50.720 161 313 1.1E-48 T 15-10-2018 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 SUPERFAMILY SSF69075 317 420 4.05E-16 T 15-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 5.8E-159 T 15-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 2.4E-46 T 15-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 321 419 1.6E-20 T 15-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 15-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_04980 e2614633726cfd7e905b9633c35589ae 446 PIRSF PIRSF000445 1 433 1.1E-157 T 15-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 C2I28_11955 94dc5ae7f9c5efae12b618476e1cfaa6 508 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 35 445 4.9E-100 T 15-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 C2I28_11955 94dc5ae7f9c5efae12b618476e1cfaa6 508 Gene3D G3DSA:1.10.4160.10 17 485 1.9E-118 T 15-10-2018 IPR038271 Purine-cytosine permease superfamily C2I28_04855 64497bb3f9d14a64834319c7b3430c5f 102 SUPERFAMILY SSF141091 1 101 2.75E-39 T 15-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04855 64497bb3f9d14a64834319c7b3430c5f 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.0E-40 T 15-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04855 64497bb3f9d14a64834319c7b3430c5f 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.2E-39 T 15-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04855 64497bb3f9d14a64834319c7b3430c5f 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.802 T 15-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04855 64497bb3f9d14a64834319c7b3430c5f 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 15-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_23495 1aaaacec143d86955c183e70d5d5a125 118 Pfam PF01381 Helix-turn-helix 5 59 4.2E-14 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_23495 1aaaacec143d86955c183e70d5d5a125 118 SMART SM00530 4 59 1.5E-13 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_23495 1aaaacec143d86955c183e70d5d5a125 118 SUPERFAMILY SSF47413 3 66 5.9E-14 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_23495 1aaaacec143d86955c183e70d5d5a125 118 Gene3D G3DSA:1.10.260.40 3 112 2.4E-19 T 15-10-2018 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 Gene3D G3DSA:1.20.140.10 218 395 1.8E-56 T 15-10-2018 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 Gene3D G3DSA:2.40.110.10 122 216 1.8E-24 T 15-10-2018 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 115 1.1E-8 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 PIRSF PIRSF016578 1 379 5.1E-30 T 15-10-2018 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 206 2.6E-8 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 SUPERFAMILY SSF47203 230 389 6.44E-20 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 239 369 6.8E-18 T 15-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 SUPERFAMILY SSF56645 17 216 4.45E-39 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_12540 834beacd8a444d9615673c5a059cecb1 395 Gene3D G3DSA:1.10.540.10 13 120 5.0E-23 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 7.6E-21 T 15-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 SUPERFAMILY SSF75420 3 84 6.28E-27 T 15-10-2018 IPR035956 RimP, N-terminal domain superfamily C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 SUPERFAMILY SSF74942 85 156 1.83E-22 T 15-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 Gene3D G3DSA:3.30.300.70 1 81 3.6E-30 T 15-10-2018 IPR035956 RimP, N-terminal domain superfamily C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 Gene3D G3DSA:2.30.30.180 88 154 2.0E-25 T 15-10-2018 C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 24.961 T 15-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 C2I28_02340 4c97915d837969ff8e921ddefdaceaf3 156 Pfam PF02576 RimP N-terminal domain 12 84 7.4E-30 T 15-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 Pfam PF01979 Amidohydrolase family 49 419 1.8E-51 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 Gene3D G3DSA:3.20.20.140 53 365 4.4E-158 T 15-10-2018 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 422 1.7E-152 T 15-10-2018 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 15-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 SUPERFAMILY SSF51338 1 422 6.41E-30 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 SUPERFAMILY SSF51556 53 366 1.59E-112 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 15-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 Gene3D G3DSA:2.30.40.10 11 418 4.4E-158 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_02845 3f6b648f49e4e8ac1d51ef2178146854 429 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 422 44.471 T 15-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_03565 917ff538244d3b6da76585f888dbf76c 214 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 11 206 2.5E-77 T 15-10-2018 IPR014196 Stage II sporulation protein M C2I28_03565 917ff538244d3b6da76585f888dbf76c 214 PIRSF PIRSF038973 1 212 8.6E-76 T 15-10-2018 IPR014196 Stage II sporulation protein M C2I28_03565 917ff538244d3b6da76585f888dbf76c 214 Pfam PF01944 Stage II sporulation protein M 25 202 3.3E-28 T 15-10-2018 IPR002798 Stage II sporulation protein M-like C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 15-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 SUPERFAMILY SSF55060 205 385 2.52E-56 T 15-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 Hamap MF_00246 Galactokinase [galK]. 24 386 46.422 T 15-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 Pfam PF00288 GHMP kinases N terminal domain 115 181 9.8E-14 T 15-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 TIGRFAM TIGR00131 gal_kin: galactokinase 3 386 1.7E-132 T 15-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 Gene3D G3DSA:3.30.70.890 202 362 3.5E-139 T 15-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 Gene3D G3DSA:3.30.230.10 21 201 3.5E-139 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 15-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00959 Mevalonate kinase family signature 24 48 1.9E-42 T 15-10-2018 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00959 Mevalonate kinase family signature 119 141 1.9E-42 T 15-10-2018 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00959 Mevalonate kinase family signature 162 181 1.9E-42 T 15-10-2018 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00959 Mevalonate kinase family signature 333 350 1.9E-42 T 15-10-2018 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 SUPERFAMILY SSF54211 2 202 1.06E-62 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 Pfam PF08544 GHMP kinases C terminal 285 366 2.7E-15 T 15-10-2018 IPR013750 GHMP kinase, C-terminal domain C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 Pfam PF10509 Galactokinase galactose-binding signature 7 56 7.9E-21 T 15-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00473 Galactokinase signature 112 130 1.9E-26 T 15-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00473 Galactokinase signature 91 102 1.9E-26 T 15-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00473 Galactokinase signature 269 283 1.9E-26 T 15-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PRINTS PR00473 Galactokinase signature 26 44 1.9E-26 T 15-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11605 8fdc2eb7c7e08d9e29831b128fcd22e2 392 PIRSF PIRSF000530 1 389 2.7E-127 T 15-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 SMART SM00968 519 638 4.5E-40 T 15-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 15-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Gene3D G3DSA:3.40.50.300 1 238 1.7E-55 T 15-10-2018 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Gene3D G3DSA:1.20.1060.20 495 680 7.0E-66 T 15-10-2018 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 PIRSF PIRSF005719 1 1185 0.0 T 15-10-2018 IPR024704 Structural maintenance of chromosomes protein C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 SUPERFAMILY SSF75553 484 687 1.83E-54 T 15-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.433 T 15-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 638 1.0E-29 T 15-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 SUPERFAMILY SSF52540 1 1164 1.88E-52 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Gene3D G3DSA:3.40.50.300 964 1186 1.0E-55 T 15-10-2018 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Gene3D G3DSA:3.30.70.1620 579 668 7.0E-66 T 15-10-2018 C2I28_02655 d4baa9c8a310208fd1992eed1bf36530 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 2.2E-65 T 15-10-2018 IPR003395 RecF/RecN/SMC, N-terminal C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.3E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.3E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 9.3E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 SUPERFAMILY SSF51735 7 247 1.37E-75 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 5.0E-57 T 15-10-2018 C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 Gene3D G3DSA:3.40.50.720 2 249 3.2E-75 T 15-10-2018 C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17915 b7e081926d80146d00e5fadc3bc35733 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19860 f37b9823fbccde18085d5db808defd7f 352 SUPERFAMILY SSF56112 13 338 2.92E-59 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_19860 f37b9823fbccde18085d5db808defd7f 352 Gene3D G3DSA:3.90.1200.10 118 351 7.2E-63 T 15-10-2018 C2I28_19860 f37b9823fbccde18085d5db808defd7f 352 Gene3D G3DSA:3.30.200.20 12 113 5.6E-27 T 15-10-2018 C2I28_19860 f37b9823fbccde18085d5db808defd7f 352 Pfam PF01636 Phosphotransferase enzyme family 36 265 1.1E-40 T 15-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I28_26400 6ff201958a0c01f9a903f7dccecc5a78 644 Gene3D G3DSA:3.40.50.300 423 644 6.3E-35 T 15-10-2018 C2I28_26400 6ff201958a0c01f9a903f7dccecc5a78 644 Gene3D G3DSA:3.40.50.300 218 373 8.0E-13 T 15-10-2018 C2I28_26400 6ff201958a0c01f9a903f7dccecc5a78 644 SUPERFAMILY SSF52540 210 624 5.58E-26 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26300 6ff201958a0c01f9a903f7dccecc5a78 644 Gene3D G3DSA:3.40.50.300 423 644 6.3E-35 T 15-10-2018 C2I28_26300 6ff201958a0c01f9a903f7dccecc5a78 644 Gene3D G3DSA:3.40.50.300 218 373 8.0E-13 T 15-10-2018 C2I28_26300 6ff201958a0c01f9a903f7dccecc5a78 644 SUPERFAMILY SSF52540 210 624 5.58E-26 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_27250 6ff201958a0c01f9a903f7dccecc5a78 644 Gene3D G3DSA:3.40.50.300 423 644 6.3E-35 T 15-10-2018 C2I28_27250 6ff201958a0c01f9a903f7dccecc5a78 644 Gene3D G3DSA:3.40.50.300 218 373 8.0E-13 T 15-10-2018 C2I28_27250 6ff201958a0c01f9a903f7dccecc5a78 644 SUPERFAMILY SSF52540 210 624 5.58E-26 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Gene3D G3DSA:3.30.230.10 224 402 4.4E-74 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 73 86 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 38 53 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 528 540 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 424 438 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 116 130 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 570 586 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 272 285 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 508 525 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR00418 DNA topoisomerase II family signature 490 506 6.3E-73 T 15-10-2018 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Pfam PF01751 Toprim domain 423 534 5.4E-19 T 15-10-2018 IPR006171 TOPRIM domain C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Pfam PF00204 DNA gyrase B 225 394 1.2E-63 T 15-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 199 212 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 591 603 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 607 623 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 9 19 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 316 332 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 364 378 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 224 246 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 184 199 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 378 398 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 PRINTS PR01159 DNA gyrase subunit B signature 474 483 8.4E-80 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 SMART SM00433 38 631 0.0 T 15-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 638 0.0 T 15-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Gene3D G3DSA:3.40.50.670 403 638 3.5E-111 T 15-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 176 1.8E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_08035 820865977f2c3cbe496834a93f931e90 638 SUPERFAMILY SSF56719 398 630 5.75E-93 T 15-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Gene3D G3DSA:3.30.565.10 6 223 1.8E-92 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_08035 820865977f2c3cbe496834a93f931e90 638 SMART SM00387 34 178 3.0E-23 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_08035 820865977f2c3cbe496834a93f931e90 638 SUPERFAMILY SSF54211 225 395 1.88E-63 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08035 820865977f2c3cbe496834a93f931e90 638 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 15-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 SUPERFAMILY SSF55874 9 217 3.8E-73 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 638 99.059 T 15-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_08035 820865977f2c3cbe496834a93f931e90 638 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 567 627 1.8E-30 T 15-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_23735 b0219e5a4da9ede8c4e90a328102b001 259 Pfam PF02673 Bacitracin resistance protein BacA 6 249 7.1E-74 T 15-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I28_23735 b0219e5a4da9ede8c4e90a328102b001 259 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 254 16.629 T 15-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I28_02380 d199ae3c0de5505f5600b1558d111445 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 238 5.2E-103 T 15-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 C2I28_02380 d199ae3c0de5505f5600b1558d111445 240 Gene3D G3DSA:3.40.1160.10 1 239 3.3E-83 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_02380 d199ae3c0de5505f5600b1558d111445 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.197 T 15-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 C2I28_02380 d199ae3c0de5505f5600b1558d111445 240 SUPERFAMILY SSF53633 5 238 5.5E-76 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_02380 d199ae3c0de5505f5600b1558d111445 240 PIRSF PIRSF005650 1 240 3.1E-98 T 15-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 C2I28_02380 d199ae3c0de5505f5600b1558d111445 240 Pfam PF00696 Amino acid kinase family 7 217 7.8E-30 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_18005 57fb9202a1bfaf0dae1c3b81dd61bd88 428 SUPERFAMILY SSF48264 6 421 4.45E-53 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18005 57fb9202a1bfaf0dae1c3b81dd61bd88 428 Pfam PF00067 Cytochrome P450 8 366 1.2E-33 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18005 57fb9202a1bfaf0dae1c3b81dd61bd88 428 PRINTS PR00465 E-class P450 group IV signature 283 299 4.5E-9 T 15-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18005 57fb9202a1bfaf0dae1c3b81dd61bd88 428 PRINTS PR00465 E-class P450 group IV signature 316 330 4.5E-9 T 15-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18005 57fb9202a1bfaf0dae1c3b81dd61bd88 428 PRINTS PR00465 E-class P450 group IV signature 332 350 4.5E-9 T 15-10-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18005 57fb9202a1bfaf0dae1c3b81dd61bd88 428 Gene3D G3DSA:1.10.630.10 3 427 1.4E-62 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_23955 ceb4c1a077aca1c5bc5a2ed1176e5c67 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 1.1E-13 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_23955 ceb4c1a077aca1c5bc5a2ed1176e5c67 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.1E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_23955 ceb4c1a077aca1c5bc5a2ed1176e5c67 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.1E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_23955 ceb4c1a077aca1c5bc5a2ed1176e5c67 177 Gene3D G3DSA:1.10.357.10 1 176 4.7E-52 T 15-10-2018 C2I28_23955 ceb4c1a077aca1c5bc5a2ed1176e5c67 177 SUPERFAMILY SSF48498 85 173 1.38E-14 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_23955 ceb4c1a077aca1c5bc5a2ed1176e5c67 177 SUPERFAMILY SSF46689 3 71 2.28E-14 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_25525 fc53688ecd9babca1acf988861e05bca 66 Pfam PF01381 Helix-turn-helix 6 60 4.4E-16 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_25525 fc53688ecd9babca1acf988861e05bca 66 SMART SM00530 5 60 1.2E-15 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_25525 fc53688ecd9babca1acf988861e05bca 66 SUPERFAMILY SSF47413 3 63 1.42E-19 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_25525 fc53688ecd9babca1acf988861e05bca 66 Gene3D G3DSA:1.10.260.40 1 65 5.1E-27 T 15-10-2018 C2I28_11515 22102f3b249b6b1e3b3165651dadb8f3 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 281 1.0E-92 T 15-10-2018 IPR003797 DegV C2I28_11515 22102f3b249b6b1e3b3165651dadb8f3 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 282 6.3E-83 T 15-10-2018 IPR003797 DegV C2I28_11515 22102f3b249b6b1e3b3165651dadb8f3 286 Gene3D G3DSA:3.30.1180.10 156 286 3.6E-49 T 15-10-2018 C2I28_11515 22102f3b249b6b1e3b3165651dadb8f3 286 Gene3D G3DSA:3.40.50.10440 5 138 5.1E-44 T 15-10-2018 C2I28_11515 22102f3b249b6b1e3b3165651dadb8f3 286 SUPERFAMILY SSF82549 1 283 5.49E-90 T 15-10-2018 C2I28_11515 22102f3b249b6b1e3b3165651dadb8f3 286 Gene3D G3DSA:2.20.28.50 28 62 5.1E-44 T 15-10-2018 C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 Pfam PF03471 Transporter associated domain 356 429 3.9E-13 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 Gene3D G3DSA:3.30.465.10 350 435 3.0E-14 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 Pfam PF00571 CBS domain 290 339 3.4E-5 T 15-10-2018 IPR000644 CBS domain C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 Pfam PF00571 CBS domain 217 272 0.001 T 15-10-2018 IPR000644 CBS domain C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 SMART SM01091 355 432 1.6E-15 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 Pfam PF01595 Domain of unknown function DUF21 8 201 1.5E-47 T 15-10-2018 IPR002550 CNNM, transmembrane domain C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 SUPERFAMILY SSF54631 204 342 1.39E-28 T 15-10-2018 C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 Gene3D G3DSA:3.10.580.10 195 349 2.2E-48 T 15-10-2018 C2I28_26955 c4736bc4e4d5c0f80fa7e590d051e2b5 439 SUPERFAMILY SSF56176 356 429 1.31E-14 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_01440 16c0d5e92f7b60499df7e00d2458c2f6 329 SUPERFAMILY SSF53448 1 241 9.38E-22 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_01440 16c0d5e92f7b60499df7e00d2458c2f6 329 Pfam PF00535 Glycosyl transferase family 2 7 176 8.1E-22 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_01440 16c0d5e92f7b60499df7e00d2458c2f6 329 Gene3D G3DSA:3.90.550.10 1 222 7.7E-24 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_21975 2d511f30455a441834869a66bd4efb4a 71 Pfam PF13131 Protein of unknown function (DUF3951) 6 51 5.5E-7 T 15-10-2018 IPR025028 Protein of unknown function DUF3951 C2I28_04555 8e108ae2608033bc50b23a996a1fd6e5 184 SUPERFAMILY SSF52499 4 182 3.79E-49 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_04555 8e108ae2608033bc50b23a996a1fd6e5 184 PRINTS PR01398 Isochorismatase signature 85 107 3.5E-6 T 15-10-2018 IPR016291 Isochorismatase GO:0008908 C2I28_04555 8e108ae2608033bc50b23a996a1fd6e5 184 PRINTS PR01398 Isochorismatase signature 159 176 3.5E-6 T 15-10-2018 IPR016291 Isochorismatase GO:0008908 C2I28_04555 8e108ae2608033bc50b23a996a1fd6e5 184 PRINTS PR01398 Isochorismatase signature 141 159 3.5E-6 T 15-10-2018 IPR016291 Isochorismatase GO:0008908 C2I28_04555 8e108ae2608033bc50b23a996a1fd6e5 184 Pfam PF00857 Isochorismatase family 9 178 5.0E-39 T 15-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I28_04555 8e108ae2608033bc50b23a996a1fd6e5 184 Gene3D G3DSA:3.40.50.850 1 180 1.8E-49 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_15385 f06708add2c8deac37a9841aa8d211b3 274 SUPERFAMILY SSF63992 1 274 4.32E-99 T 15-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily C2I28_15385 f06708add2c8deac37a9841aa8d211b3 274 Pfam PF04951 D-aminopeptidase 1 262 4.6E-92 T 15-10-2018 IPR007035 Peptidase M55, D-aminopeptidase C2I28_15385 f06708add2c8deac37a9841aa8d211b3 274 Gene3D G3DSA:3.40.50.10780 1 213 7.0E-98 T 15-10-2018 IPR027476 D-aminopeptidase, N-terminal C2I28_15385 f06708add2c8deac37a9841aa8d211b3 274 Gene3D G3DSA:3.30.1360.130 118 261 7.0E-98 T 15-10-2018 C2I28_15385 f06708add2c8deac37a9841aa8d211b3 274 PIRSF PIRSF015853 1 271 1.7E-103 T 15-10-2018 IPR007035 Peptidase M55, D-aminopeptidase C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 Gene3D G3DSA:2.10.109.10 56 183 3.5E-34 T 15-10-2018 C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 15 177 1.4E-41 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 Pfam PF00717 Peptidase S24-like 36 101 6.0E-18 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 4.2E-18 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 4.2E-18 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 4.2E-18 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 SUPERFAMILY SSF51306 29 182 1.44E-45 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_14045 1da22a06e8d440c9f3764a1425e6a159 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 SUPERFAMILY SSF54211 3 86 3.04E-32 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 Gene3D G3DSA:3.30.230.40 1 89 1.8E-37 T 15-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 SUPERFAMILY SSF54211 87 179 3.54E-34 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 1.6E-63 T 15-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 15-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 Gene3D G3DSA:3.30.230.40 90 194 3.5E-39 T 15-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 42.071 T 15-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I28_06920 d95c10cf2533db25541cd12dd447272d 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 15-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 C2I28_09625 2620cf64d7b771b91aeb8049e46e772d 242 SMART SM00382 26 213 3.7E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09625 2620cf64d7b771b91aeb8049e46e772d 242 SUPERFAMILY SSF52540 1 234 1.25E-81 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09625 2620cf64d7b771b91aeb8049e46e772d 242 PIRSF PIRSF039085 1 241 6.9E-116 T 15-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I28_09625 2620cf64d7b771b91aeb8049e46e772d 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_09625 2620cf64d7b771b91aeb8049e46e772d 242 Pfam PF00005 ABC transporter 17 165 9.1E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09625 2620cf64d7b771b91aeb8049e46e772d 242 Gene3D G3DSA:3.40.50.300 1 241 4.1E-77 T 15-10-2018 C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 358 429 2.3E-7 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 SUPERFAMILY SSF52540 5 464 4.0E-93 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 466 44.358 T 15-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 Gene3D G3DSA:1.10.8.60 358 463 1.6E-40 T 15-10-2018 C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 150 3.9E-7 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 SMART SM00382 50 355 7.6E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 5 466 4.1E-219 T 15-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 Pfam PF07724 AAA domain (Cdc48 subfamily) 211 352 2.5E-42 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_02555 7d79066c3d18d4253d6fb0b5afd14e4b 466 SMART SM01086 358 452 1.1E-23 T 15-10-2018 IPR019489 Clp ATPase, C-terminal C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 Gene3D G3DSA:3.90.1150.10 10 421 1.7E-182 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 Pfam PF00202 Aminotransferase class-III 34 395 1.2E-76 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 Gene3D G3DSA:3.40.640.10 72 319 1.7E-182 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 SUPERFAMILY SSF53383 4 426 3.5E-131 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 104.473 T 15-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I28_04955 074e3b374c52f88d4b7131786141ce59 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 426 3.0E-200 T 15-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 C2I28_24025 dd887c392754c5e94724a61853b5b41c 315 Pfam PF01032 FecCD transport family 30 310 2.3E-53 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_24025 dd887c392754c5e94724a61853b5b41c 315 Gene3D G3DSA:1.10.3470.10 4 314 7.6E-56 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_24025 dd887c392754c5e94724a61853b5b41c 315 SUPERFAMILY SSF81345 7 310 4.71E-56 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 Pfam PF13481 AAA domain 71 222 1.2E-18 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 SMART SM00382 90 244 4.0E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 Pfam PF13541 Subunit ChlI of Mg-chelatase 364 430 6.2E-9 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 Gene3D G3DSA:3.40.50.300 63 288 3.7E-45 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 SUPERFAMILY SSF52540 71 291 8.6E-52 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 44.906 T 15-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 2.3E-213 T 15-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 SUPERFAMILY SSF54211 255 457 7.59E-42 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 10 34 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 124 141 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 322 345 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 213 241 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 174 198 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 82 110 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 PRINTS PR01874 DNA repair protein radA signature 248 274 1.4E-93 T 15-10-2018 C2I28_08545 fc72beb6783c8e7315df190bfe652dbb 458 Gene3D G3DSA:3.30.230.10 289 457 4.8E-19 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_00620 b719888645697ae3691d0f08fb60640d 375 Pfam PF04303 PrpF protein 1 366 1.3E-142 T 15-10-2018 IPR007400 PrpF protein C2I28_00620 b719888645697ae3691d0f08fb60640d 375 SUPERFAMILY SSF54506 170 366 1.57E-53 T 15-10-2018 C2I28_00620 b719888645697ae3691d0f08fb60640d 375 SUPERFAMILY SSF54506 2 165 1.33E-61 T 15-10-2018 C2I28_00620 b719888645697ae3691d0f08fb60640d 375 Gene3D G3DSA:3.10.310.10 4 364 2.9E-140 T 15-10-2018 C2I28_00620 b719888645697ae3691d0f08fb60640d 375 Gene3D G3DSA:3.10.310.10 172 347 2.9E-140 T 15-10-2018 C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 SUPERFAMILY SSF52172 1 172 5.86E-42 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 SMART SM00862 145 219 3.3E-21 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 Gene3D G3DSA:3.40.50.2300 1 127 1.8E-37 T 15-10-2018 C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 219 5.4E-22 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 Gene3D G3DSA:1.10.10.10 128 224 1.5E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 Pfam PF00072 Response regulator receiver domain 4 112 1.8E-28 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_24305 dacb91b5a5e699f8888a9aa75e4d2b98 224 SMART SM00448 2 112 1.0E-41 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_17150 1d6f38a2a858e24f602db9891852a545 337 Gene3D G3DSA:3.40.718.10 1 332 6.5E-139 T 15-10-2018 C2I28_17150 1d6f38a2a858e24f602db9891852a545 337 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 33 325 1.4E-105 T 15-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 C2I28_17150 1d6f38a2a858e24f602db9891852a545 337 SUPERFAMILY SSF53659 3 330 4.18E-107 T 15-10-2018 C2I28_17150 1d6f38a2a858e24f602db9891852a545 337 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 328 2.0E-108 T 15-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 C2I28_18195 1c3f94e5c5654c8dbe5adce96ce0cc60 181 Pfam PF16107 Domain of unknown function (DUF4825) 49 133 9.9E-11 T 15-10-2018 IPR032250 Domain of unknown function DUF4825 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 117 5.4E-33 T 15-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 SMART SM01232 134 226 1.5E-45 T 15-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 SUPERFAMILY SSF46946 134 223 6.02E-30 T 15-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 SUPERFAMILY SSF57716 222 274 3.33E-18 T 15-10-2018 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 Gene3D G3DSA:3.20.190.10 2 128 6.8E-41 T 15-10-2018 IPR035937 MutM-like, N-terminal C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 43.976 T 15-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 Gene3D G3DSA:1.10.8.50 136 274 6.7E-51 T 15-10-2018 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 224 1.0E-31 T 15-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 15-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 SUPERFAMILY SSF81624 2 139 3.53E-43 T 15-10-2018 IPR035937 MutM-like, N-terminal C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 3.5E-110 T 15-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 Pfam PF06827 Zinc finger found in FPG and IleRS 246 274 4.1E-10 T 15-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 C2I28_05370 2f3f93fd1e6d389e96540892b14f9945 277 SMART SM00898 2 118 1.1E-49 T 15-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 C2I28_09635 38be7667ec6726c1a53ea26bf0f4fb79 212 SUPERFAMILY SSF161098 13 194 2.35E-44 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_09635 38be7667ec6726c1a53ea26bf0f4fb79 212 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 103 1.1E-19 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_09635 38be7667ec6726c1a53ea26bf0f4fb79 212 Gene3D G3DSA:1.10.3720.10 1 211 2.0E-51 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_09635 38be7667ec6726c1a53ea26bf0f4fb79 212 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 209 1.4E-19 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_17475 27d095fcdefff7c79eb3d08459268308 498 SUPERFAMILY SSF89796 237 435 4.32E-48 T 15-10-2018 IPR023606 CoA-transferase family III domain superfamily C2I28_17475 27d095fcdefff7c79eb3d08459268308 498 Gene3D G3DSA:3.40.50.10540 234 491 2.2E-48 T 15-10-2018 IPR023606 CoA-transferase family III domain superfamily C2I28_17475 27d095fcdefff7c79eb3d08459268308 498 Pfam PF02515 CoA-transferase family III 239 460 1.1E-40 T 15-10-2018 IPR003673 CoA-transferase family III GO:0003824 C2I28_17475 27d095fcdefff7c79eb3d08459268308 498 SUPERFAMILY SSF89796 54 225 1.7E-16 T 15-10-2018 IPR023606 CoA-transferase family III domain superfamily C2I28_16840 350c5a55616a796a90f38dbba9542a27 132 SUPERFAMILY SSF109854 1 132 6.96E-26 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16840 350c5a55616a796a90f38dbba9542a27 132 Pfam PF12867 DinB superfamily 2 116 9.8E-8 T 15-10-2018 IPR024775 DinB-like domain C2I28_16840 350c5a55616a796a90f38dbba9542a27 132 Gene3D G3DSA:1.20.120.450 1 132 9.1E-23 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_13220 ab3204ead831a6899875b94c58cffadd 111 PIRSF PIRSF000699 1 109 2.0E-37 T 15-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I28_13220 ab3204ead831a6899875b94c58cffadd 111 SUPERFAMILY SSF46973 5 103 3.01E-34 T 15-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 C2I28_13220 ab3204ead831a6899875b94c58cffadd 111 Gene3D G3DSA:1.20.58.280 2 108 1.4E-36 T 15-10-2018 C2I28_13220 ab3204ead831a6899875b94c58cffadd 111 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 11 102 1.5E-34 T 15-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I28_13055 695b4b137219f25aea94f9c066045205 261 Gene3D G3DSA:3.40.50.300 1 245 7.8E-69 T 15-10-2018 C2I28_13055 695b4b137219f25aea94f9c066045205 261 SUPERFAMILY SSF52540 6 227 2.88E-63 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_13055 695b4b137219f25aea94f9c066045205 261 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_13055 695b4b137219f25aea94f9c066045205 261 SMART SM00382 30 213 5.3E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_13055 695b4b137219f25aea94f9c066045205 261 Pfam PF00005 ABC transporter 22 164 5.3E-27 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 Gene3D G3DSA:1.10.10.10 130 225 2.6E-30 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 SUPERFAMILY SSF52172 3 181 5.13E-42 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 SMART SM00862 148 223 2.1E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 SMART SM00448 3 112 7.5E-45 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 Pfam PF00072 Response regulator receiver domain 5 112 6.6E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 5.9E-24 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_25200 b4bb457bc5476f4938f881d68296f866 225 Gene3D G3DSA:3.40.50.2300 1 129 3.6E-38 T 15-10-2018 C2I28_21950 e5b404debe82d56b2fba558fe7461f51 419 Pfam PF01547 Bacterial extracellular solute-binding protein 47 337 5.6E-34 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_21950 e5b404debe82d56b2fba558fe7461f51 419 SUPERFAMILY SSF53850 19 417 3.16E-71 T 15-10-2018 C2I28_21950 e5b404debe82d56b2fba558fe7461f51 419 Gene3D G3DSA:3.40.190.10 49 357 4.6E-125 T 15-10-2018 C2I28_21950 e5b404debe82d56b2fba558fe7461f51 419 Gene3D G3DSA:3.40.190.10 142 398 4.6E-125 T 15-10-2018 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 56 4.6E-27 T 15-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 99 111 4.6E-27 T 15-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 18 33 4.6E-27 T 15-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 84 99 4.6E-27 T 15-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 112 127 4.6E-27 T 15-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 11 137 1.1E-40 T 15-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 SUPERFAMILY SSF50891 13 137 5.84E-48 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 39 56 - T 15-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 PIRSF PIRSF001467 3 144 3.5E-42 T 15-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 C2I28_03470 ddcb3e0da1a480bf2e7b1e54d0c332ee 144 Gene3D G3DSA:2.40.100.10 1 144 1.0E-59 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_17775 9e0462b2b53aecebed91f87e2ef41ac3 210 Pfam PF14005 YpjP-like protein 79 208 3.0E-58 T 15-10-2018 IPR025616 YpjP-like protein C2I28_15585 274b8513042c360ce4ce724a42b81337 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 82 95 1.2E-23 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_15585 274b8513042c360ce4ce724a42b81337 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 40 59 1.2E-23 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_15585 274b8513042c360ce4ce724a42b81337 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 241 257 1.2E-23 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_15585 274b8513042c360ce4ce724a42b81337 319 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 242 252 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_15585 274b8513042c360ce4ce724a42b81337 319 Pfam PF00082 Subtilase family 40 285 3.0E-60 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_15585 274b8513042c360ce4ce724a42b81337 319 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 86 96 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_15585 274b8513042c360ce4ce724a42b81337 319 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 45 56 - T 15-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I28_15585 274b8513042c360ce4ce724a42b81337 319 Gene3D G3DSA:3.40.50.200 3 306 1.5E-112 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_15585 274b8513042c360ce4ce724a42b81337 319 SUPERFAMILY SSF52743 23 299 2.36E-87 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_18150 82071cbfa6e0ea938e36889b81934026 257 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_18150 82071cbfa6e0ea938e36889b81934026 257 SMART SM00382 26 216 8.7E-15 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_18150 82071cbfa6e0ea938e36889b81934026 257 SUPERFAMILY SSF52540 1 238 3.82E-79 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18150 82071cbfa6e0ea938e36889b81934026 257 PIRSF PIRSF039085 1 244 1.2E-113 T 15-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I28_18150 82071cbfa6e0ea938e36889b81934026 257 Gene3D G3DSA:3.40.50.300 1 246 6.7E-77 T 15-10-2018 C2I28_18150 82071cbfa6e0ea938e36889b81934026 257 Pfam PF00005 ABC transporter 17 168 8.7E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 SMART SM00331 163 377 1.6E-23 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 Gene3D G3DSA:3.40.50.12740 1 165 7.1E-40 T 15-10-2018 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 SUPERFAMILY SSF81606 179 376 8.37E-8 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 Gene3D G3DSA:3.60.40.10 166 379 1.1E-44 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 SMART SM00448 1 122 3.7E-36 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 190 377 8.8E-37 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 Pfam PF00072 Response regulator receiver domain 3 122 5.1E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15740 44ddabcdfb8ce94446f10a05d52bd2b6 379 SUPERFAMILY SSF52172 1 133 9.39E-35 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 15-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 Gene3D G3DSA:3.30.70.100 1 67 2.5E-27 T 15-10-2018 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 Pfam PF00403 Heavy-metal-associated domain 5 66 6.5E-18 T 15-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 68 9.7E-28 T 15-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 PRINTS PR00944 Copper ion binding protein signature 15 28 1.1E-9 T 15-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 PRINTS PR00944 Copper ion binding protein signature 28 41 1.1E-9 T 15-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 PRINTS PR00944 Copper ion binding protein signature 3 15 1.1E-9 T 15-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 PRINTS PR00944 Copper ion binding protein signature 54 67 1.1E-9 T 15-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 C2I28_17505 fe05a9ffd01458da09b201574a36f632 68 SUPERFAMILY SSF55008 2 67 3.14E-22 T 15-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 C2I28_26630 1416ff7589b0ee1c3dc8c78552d8aaaf 195 Pfam PF14568 SMI1-KNR4 cell-wall 30 160 2.5E-21 T 15-10-2018 C2I28_26630 1416ff7589b0ee1c3dc8c78552d8aaaf 195 SUPERFAMILY SSF160631 25 165 1.03E-22 T 15-10-2018 C2I28_26630 1416ff7589b0ee1c3dc8c78552d8aaaf 195 SMART SM00860 25 162 2.2E-6 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_26630 1416ff7589b0ee1c3dc8c78552d8aaaf 195 Gene3D G3DSA:3.40.1580.10 20 174 4.8E-25 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_07710 b3df1be705f4a6803aee72cc03165601 599 Pfam PF02254 TrkA-N domain 402 485 2.1E-7 T 15-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I28_07710 b3df1be705f4a6803aee72cc03165601 599 Gene3D G3DSA:1.20.1530.20 2 393 8.5E-19 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_07710 b3df1be705f4a6803aee72cc03165601 599 SUPERFAMILY SSF51735 402 493 1.83E-8 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_07710 b3df1be705f4a6803aee72cc03165601 599 Pfam PF00999 Sodium/hydrogen exchanger family 10 390 5.8E-35 T 15-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I28_07710 b3df1be705f4a6803aee72cc03165601 599 Gene3D G3DSA:3.40.50.720 398 516 3.2E-9 T 15-10-2018 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 6 217 1.7E-53 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 ProSitePatterns PS01218 TatC family signature. 145 164 - T 15-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 76 94 1.6E-35 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 5 32 1.6E-35 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 94 120 1.6E-35 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 145 173 1.6E-35 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 230 14.949 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_07040 d7155a1af80f2e4fd30070023421415d 238 Pfam PF00902 Sec-independent protein translocase protein (TatC) 8 212 1.7E-53 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_04480 0fabc0f2da52eb79e33715377a0af78b 368 Pfam PF01926 50S ribosome-binding GTPase 164 226 5.7E-14 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04480 0fabc0f2da52eb79e33715377a0af78b 368 Gene3D G3DSA:3.40.50.300 58 226 4.5E-52 T 15-10-2018 C2I28_04480 0fabc0f2da52eb79e33715377a0af78b 368 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 7 368 1.0E-162 T 15-10-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH C2I28_04480 0fabc0f2da52eb79e33715377a0af78b 368 SUPERFAMILY SSF52540 71 281 1.19E-33 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06965 6625bec8b4b14a5eda419dede9fb855a 64 Pfam PF04024 PspC domain 2 59 2.8E-17 T 15-10-2018 IPR007168 Phage shock protein, PspC, N-terminal C2I28_02315 ddbc5ce1bca7e0e72f7020090ac142a6 92 SUPERFAMILY SSF103007 1 92 3.27E-29 T 15-10-2018 IPR036746 TT1725-like superfamily C2I28_02315 ddbc5ce1bca7e0e72f7020090ac142a6 92 Pfam PF04456 Protein of unknown function (DUF503) 2 85 9.7E-30 T 15-10-2018 IPR007546 Protein of unknown function DUF503 C2I28_02315 ddbc5ce1bca7e0e72f7020090ac142a6 92 Gene3D G3DSA:3.30.70.1120 1 91 4.3E-23 T 15-10-2018 IPR036746 TT1725-like superfamily C2I28_22330 49fdd5aada85ae50567bf48d94792951 462 Pfam PF10011 Predicted membrane protein (DUF2254) 35 403 9.3E-109 T 15-10-2018 IPR018723 Protein of unknown function DUF2254, membrane C2I28_00910 89f4ce14a99dec8f57976d85dd9e9409 636 Pfam PF02687 FtsX-like permease family 85 170 7.8E-10 T 15-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I28_00910 89f4ce14a99dec8f57976d85dd9e9409 636 PIRSF PIRSF018968 1 636 1.6E-118 T 15-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I28_22215 9adfb44e9448fd8cb260eda053b983e3 414 Pfam PF04143 Sulphur transport 67 393 6.3E-76 T 15-10-2018 IPR007272 Sulphur transport domain C2I28_00060 6a7f1c9622a984a5617f4b0496b171d7 194 Gene3D G3DSA:3.40.50.880 1 192 2.2E-42 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_00060 6a7f1c9622a984a5617f4b0496b171d7 194 Pfam PF01965 DJ-1/PfpI family 2 176 5.0E-29 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_00060 6a7f1c9622a984a5617f4b0496b171d7 194 SUPERFAMILY SSF52317 1 191 5.73E-42 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_26170 6a7f1c9622a984a5617f4b0496b171d7 194 Gene3D G3DSA:3.40.50.880 1 192 2.2E-42 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_26170 6a7f1c9622a984a5617f4b0496b171d7 194 Pfam PF01965 DJ-1/PfpI family 2 176 5.0E-29 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_26170 6a7f1c9622a984a5617f4b0496b171d7 194 SUPERFAMILY SSF52317 1 191 5.73E-42 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 SUPERFAMILY SSF53850 5 267 1.78E-68 T 15-10-2018 C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 Gene3D G3DSA:3.40.190.10 42 260 9.6E-68 T 15-10-2018 C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 SMART SM00062 43 268 1.8E-68 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 266 1.6E-61 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 Gene3D G3DSA:3.40.190.10 134 227 9.6E-68 T 15-10-2018 C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 69 82 - T 15-10-2018 IPR018313 Solute-binding protein family 3, conserved site C2I28_03725 3872c03b482f2b308fa14a228a05166c 269 SMART SM00079 43 267 2.9E-6 T 15-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 PRINTS PR00189 Transthyretin signature 96 118 7.9E-5 T 15-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 PRINTS PR00189 Transthyretin signature 3 23 7.9E-5 T 15-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 SUPERFAMILY SSF49472 2 118 1.7E-36 T 15-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 Gene3D G3DSA:2.60.40.180 1 118 4.8E-38 T 15-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 Pfam PF00576 HIUase/Transthyretin family 4 117 1.4E-33 T 15-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 ProSitePatterns PS00769 Transthyretin signature 2. 101 113 - T 15-10-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 15-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 C2I28_20710 88f25785b081a826bd3211e4eac3b12e 118 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 118 3.4E-37 T 15-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 3 453 3.8E-192 T 15-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 Pfam PF00367 phosphotransferase system, EIIB 9 41 5.7E-14 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 Pfam PF02378 Phosphotransferase system, EIIC 111 397 1.3E-51 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 112 1.2E-15 T 15-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 SUPERFAMILY SSF55604 6 81 2.62E-19 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_01650 4b48ea032b6a464d742d8a9216e0cfb0 459 Gene3D G3DSA:3.30.1360.60 1 77 3.2E-24 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 SMART SM00740 607 666 2.3E-4 T 15-10-2018 IPR005543 PASTA domain C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 SMART SM00740 667 723 0.77 T 15-10-2018 IPR005543 PASTA domain C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 SUPERFAMILY SSF54184 668 721 1.57E-9 T 15-10-2018 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 SUPERFAMILY SSF54184 609 665 9.29E-10 T 15-10-2018 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Gene3D G3DSA:3.30.450.330 246 586 8.3E-96 T 15-10-2018 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Pfam PF00905 Penicillin binding protein transpeptidase domain 271 582 1.0E-78 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Gene3D G3DSA:3.40.710.10 303 498 8.3E-96 T 15-10-2018 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Pfam PF03793 PASTA domain 669 721 1.1E-4 T 15-10-2018 IPR005543 PASTA domain C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 SUPERFAMILY SSF56601 195 596 3.93E-89 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Gene3D G3DSA:3.30.70.2110 81 167 1.0E-52 T 15-10-2018 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 SUPERFAMILY SSF56519 56 244 3.53E-41 T 15-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 223 4.3E-22 T 15-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Gene3D G3DSA:2.20.70.70 57 230 1.0E-52 T 15-10-2018 C2I28_02980 db07dc5903ee3bbbcead4690140c042c 752 Gene3D G3DSA:3.90.1310.10 62 211 1.0E-52 T 15-10-2018 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 SUPERFAMILY SSF51735 2 167 1.92E-55 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 405 6.1E-68 T 15-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 139 169 - T 15-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 Pfam PF02056 Family 4 glycosyl hydrolase 3 184 2.2E-68 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 Gene3D G3DSA:3.90.1820.20 1 428 3.5E-148 T 15-10-2018 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 SUPERFAMILY SSF56327 168 433 1.3E-76 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 72 88 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21935 5868ddcf186d48d6f485ab6c545eb074 440 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 1.2E-38 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_21720 f7914d0aa11f6a6dad64dc096a5a7b66 276 Gene3D G3DSA:3.40.50.1820 43 172 5.1E-5 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_21720 f7914d0aa11f6a6dad64dc096a5a7b66 276 SUPERFAMILY SSF53474 43 262 3.03E-8 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_13105 b86502c85bc9301c217e55fa37a08d6e 57 Pfam PF02416 mttA/Hcf106 family 3 54 4.3E-23 T 15-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 C2I28_13105 b86502c85bc9301c217e55fa37a08d6e 57 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 46 2.8E-19 T 15-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I28_13105 b86502c85bc9301c217e55fa37a08d6e 57 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 57 17.121 T 15-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I28_09300 499719f972cdc273da3dfcbfefd6ca43 149 Pfam PF00583 Acetyltransferase (GNAT) family 16 125 6.6E-20 T 15-10-2018 IPR000182 GNAT domain C2I28_09300 499719f972cdc273da3dfcbfefd6ca43 149 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 2.8E-46 T 15-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 C2I28_09300 499719f972cdc273da3dfcbfefd6ca43 149 SUPERFAMILY SSF55729 1 138 3.99E-36 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_09300 499719f972cdc273da3dfcbfefd6ca43 149 Gene3D G3DSA:3.40.630.30 6 149 1.4E-45 T 15-10-2018 C2I28_21150 3fcdd658b368736c38c76202d5f267c9 389 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 99 375 8.9E-73 T 15-10-2018 IPR010897 Sporulation stage II, protein P C2I28_21150 3fcdd658b368736c38c76202d5f267c9 389 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 175 379 1.5E-70 T 15-10-2018 IPR010897 Sporulation stage II, protein P C2I28_21150 3fcdd658b368736c38c76202d5f267c9 389 SUPERFAMILY SSF53187 233 379 2.09E-11 T 15-10-2018 C2I28_01745 b5a9b6018454295f647b51d059bb8c3a 281 Gene3D G3DSA:3.30.470.10 1 115 9.5E-33 T 15-10-2018 C2I28_01745 b5a9b6018454295f647b51d059bb8c3a 281 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 8 267 7.1E-85 T 15-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 C2I28_01745 b5a9b6018454295f647b51d059bb8c3a 281 Pfam PF01063 Amino-transferase class IV 30 251 4.7E-54 T 15-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I28_01745 b5a9b6018454295f647b51d059bb8c3a 281 SUPERFAMILY SSF56752 4 270 1.96E-73 T 15-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I28_01745 b5a9b6018454295f647b51d059bb8c3a 281 Gene3D G3DSA:3.20.10.10 119 277 9.3E-53 T 15-10-2018 C2I28_01745 b5a9b6018454295f647b51d059bb8c3a 281 ProSitePatterns PS00770 Aminotransferases class-IV signature. 177 206 - T 15-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I28_13810 9395b2d52f6a3b4207f7ea6f38d32838 526 SUPERFAMILY SSF51395 8 512 1.65E-107 T 15-10-2018 C2I28_13810 9395b2d52f6a3b4207f7ea6f38d32838 526 PIRSF PIRSF500060 1 525 7.1E-209 T 15-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria C2I28_13810 9395b2d52f6a3b4207f7ea6f38d32838 526 PIRSF PIRSF006429 1 523 4.2E-156 T 15-10-2018 IPR024188 Glutamate synthase large subunit-like protein C2I28_13810 9395b2d52f6a3b4207f7ea6f38d32838 526 Gene3D G3DSA:3.20.20.70 119 523 2.3E-100 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_13810 9395b2d52f6a3b4207f7ea6f38d32838 526 Pfam PF01645 Conserved region in glutamate synthase 119 495 2.7E-108 T 15-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 PRINTS PR00412 Epoxide hydrolase signature 229 245 2.4E-13 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 PRINTS PR00412 Epoxide hydrolase signature 28 46 2.4E-13 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 PRINTS PR00412 Epoxide hydrolase signature 262 284 2.4E-13 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 PRINTS PR00412 Epoxide hydrolase signature 107 120 2.4E-13 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 PRINTS PR00412 Epoxide hydrolase signature 93 106 2.4E-13 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 Gene3D G3DSA:3.40.50.1820 2 286 1.2E-93 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 Pfam PF00561 alpha/beta hydrolase fold 23 274 5.4E-26 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_22760 81a8644c8d590393a406b3bd6ce3b705 287 SUPERFAMILY SSF53474 4 287 4.5E-66 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.161 T 15-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 Gene3D G3DSA:2.40.50.620 33 97 1.0E-12 T 15-10-2018 C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 Gene3D G3DSA:2.40.30.10 133 209 1.6E-17 T 15-10-2018 C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 15-10-2018 IPR019926 Ribosomal protein L3, conserved site C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 SUPERFAMILY SSF50447 2 207 1.15E-80 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 2.9E-86 T 15-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08685 c41f66494db80daf5753f9cefec8aeb4 209 Pfam PF00297 Ribosomal protein L3 99 181 2.5E-15 T 15-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 SUPERFAMILY SSF51419 30 299 3.78E-79 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 297 4.1E-63 T 15-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 1.5E-14 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 1.5E-14 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 1.5E-14 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 1.5E-14 T 15-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 40.298 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 SUPERFAMILY SSF50621 278 432 8.16E-55 T 15-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 2.2E-27 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 2.2E-27 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 2.2E-27 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 2.2E-27 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 431 3.0E-154 T 15-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 35 388 7.1E-19 T 15-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 Gene3D G3DSA:2.40.37.10 17 427 2.5E-157 T 15-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 C2I28_19795 04559fd556b38ff97a2fe1f586a69f24 442 Gene3D G3DSA:3.20.20.10 38 297 2.5E-157 T 15-10-2018 IPR029066 PLP-binding barrel C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 15-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 Pfam PF02629 CoA binding domain 6 99 2.5E-29 T 15-10-2018 IPR003781 CoA-binding GO:0048037 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.9E-41 T 15-10-2018 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 3.9E-41 T 15-10-2018 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 3.9E-41 T 15-10-2018 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 3.9E-41 T 15-10-2018 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 SUPERFAMILY SSF51735 1 122 1.03E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 PIRSF PIRSF001553 1 291 5.3E-132 T 15-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 Gene3D G3DSA:3.40.50.261 124 289 3.7E-71 T 15-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 Gene3D G3DSA:3.40.50.720 1 123 2.0E-50 T 15-10-2018 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 SMART SM00881 4 100 9.4E-32 T 15-10-2018 IPR003781 CoA-binding GO:0048037 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 Pfam PF00549 CoA-ligase 151 265 3.9E-18 T 15-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 15-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 SUPERFAMILY SSF52210 123 287 2.49E-53 T 15-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.312 T 15-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_02585 d089e6e3ac10b48ec6e0cfce144b5c50 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 9.7E-146 T 15-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_06905 eb9efbbcc8f637fdc22f12223fc7d82c 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 1.4E-119 T 15-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 C2I28_06905 eb9efbbcc8f637fdc22f12223fc7d82c 252 SUPERFAMILY SSF51366 1 252 2.9E-82 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_06905 eb9efbbcc8f637fdc22f12223fc7d82c 252 Gene3D G3DSA:3.20.20.70 1 252 7.4E-107 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_06905 eb9efbbcc8f637fdc22f12223fc7d82c 252 Pfam PF00977 Histidine biosynthesis protein 5 235 2.5E-89 T 15-10-2018 IPR006062 Histidine biosynthesis GO:0000105 C2I28_06905 eb9efbbcc8f637fdc22f12223fc7d82c 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 49.204 T 15-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 C2I28_15660 459852c8e7ace0c26b4db27fe144d483 414 SUPERFAMILY SSF103473 4 398 7.59E-59 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15660 459852c8e7ace0c26b4db27fe144d483 414 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 10 394 3.1E-123 T 15-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 C2I28_15660 459852c8e7ace0c26b4db27fe144d483 414 Gene3D G3DSA:1.20.1720.10 13 393 6.7E-94 T 15-10-2018 C2I28_15660 459852c8e7ace0c26b4db27fe144d483 414 Pfam PF07690 Major Facilitator Superfamily 19 362 2.5E-36 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 SUPERFAMILY SSF52540 638 897 2.47E-31 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 Gene3D G3DSA:3.40.50.300 618 958 4.7E-80 T 15-10-2018 C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 Pfam PF01580 FtsK/SpoIIIE family 966 1160 3.5E-26 T 15-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 Pfam PF01580 FtsK/SpoIIIE family 641 857 1.7E-30 T 15-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 207 1482 0.0 T 15-10-2018 IPR023839 Firmicutes EssC, C-terminal C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 Gene3D G3DSA:3.40.50.300 1257 1484 2.6E-20 T 15-10-2018 C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 Gene3D G3DSA:3.40.50.300 959 1244 9.6E-67 T 15-10-2018 C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 Pfam PF12538 DNA transporter 4 120 3.5E-13 T 15-10-2018 IPR022206 Firmicutes EssC, N-terminal C2I28_09830 4ae821c36282468ecb87d72c89572676 1492 SUPERFAMILY SSF52540 977 1186 8.36E-12 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09910 b23f2ab8be72514e655f55b3555765e2 170 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 1.7E-55 T 15-10-2018 IPR006286 Deglycase PfpI C2I28_09910 b23f2ab8be72514e655f55b3555765e2 170 Gene3D G3DSA:3.40.50.880 1 169 2.0E-51 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09910 b23f2ab8be72514e655f55b3555765e2 170 SUPERFAMILY SSF52317 1 169 4.44E-45 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09910 b23f2ab8be72514e655f55b3555765e2 170 Pfam PF01965 DJ-1/PfpI family 3 166 2.1E-52 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 Gene3D G3DSA:3.30.413.10 429 570 4.3E-36 T 15-10-2018 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 17 562 4.3E-282 T 15-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 481 497 - T 15-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 SUPERFAMILY SSF55124 13 145 2.78E-34 T 15-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 PRINTS PR00397 Sirohaem Fe-binding site signature 481 499 5.6E-8 T 15-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 PRINTS PR00397 Sirohaem Fe-binding site signature 433 451 5.6E-8 T 15-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 SUPERFAMILY SSF55124 348 424 3.11E-21 T 15-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 170 332 6.7E-48 T 15-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 8 573 58.334 T 15-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 SUPERFAMILY SSF56014 146 346 3.01E-60 T 15-10-2018 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 SUPERFAMILY SSF56014 431 563 1.57E-32 T 15-10-2018 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 433 561 0.041 T 15-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 355 419 2.2E-14 T 15-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_23590 d12696fd0a5d230b2fb1bd921b45771a 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 75 136 1.6E-15 T 15-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 Gene3D G3DSA:3.50.50.100 1 391 9.3E-120 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 SUPERFAMILY SSF51905 2 322 2.79E-32 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.0E-6 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.0E-6 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 1.0E-6 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 1.2E-47 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.1E-11 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.1E-11 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.1E-11 T 15-10-2018 C2I28_21270 c0b4be1f0e442909053834a4c22822a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-11 T 15-10-2018 C2I28_07445 d232804578e863847e882bfd71e9077c 214 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 9.8E-101 T 15-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_07445 d232804578e863847e882bfd71e9077c 214 SUPERFAMILY SSF51569 1 211 2.93E-77 T 15-10-2018 C2I28_07445 d232804578e863847e882bfd71e9077c 214 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_07445 d232804578e863847e882bfd71e9077c 214 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 201 5.6E-54 T 15-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_07445 d232804578e863847e882bfd71e9077c 214 Gene3D G3DSA:3.20.20.70 1 213 1.5E-86 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_07445 d232804578e863847e882bfd71e9077c 214 Hamap MF_00494 Probable transaldolase [tal]. 1 214 46.476 T 15-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_07445 d232804578e863847e882bfd71e9077c 214 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_15960 ded4da59da7cc603ac336a41d63b7a0d 217 SUPERFAMILY SSF161098 7 215 2.22E-47 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15960 ded4da59da7cc603ac336a41d63b7a0d 217 Gene3D G3DSA:1.10.3720.10 3 217 5.6E-50 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15960 ded4da59da7cc603ac336a41d63b7a0d 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 215 1.8E-21 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_19460 c6fa838db50733fb5bab63878c8db2c5 69 Pfam PF14169 Cold-inducible protein YdjO 1 60 8.4E-23 T 15-10-2018 IPR025916 Cold-inducible protein YdjO C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 Pfam PF04552 Sigma-54, DNA binding domain 273 431 1.7E-56 T 15-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 48 4.5E-12 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 431 3.3E-129 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 320 339 - T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 412 419 - T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 PIRSF PIRSF000774 1 433 2.0E-125 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 Gene3D G3DSA:1.10.10.1330 79 211 1.4E-25 T 15-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 Pfam PF04963 Sigma-54 factor, core binding domain 74 259 2.1E-53 T 15-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 Gene3D G3DSA:1.10.10.60 372 432 1.8E-21 T 15-10-2018 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 PRINTS PR00045 Sigma-54 factor signature 332 344 6.8E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 PRINTS PR00045 Sigma-54 factor signature 407 425 6.8E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 PRINTS PR00045 Sigma-54 factor signature 348 359 6.8E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_06845 f15be9c6dfd7a4a07b56219e784009ba 436 PRINTS PR00045 Sigma-54 factor signature 145 162 6.8E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_13195 6dcbe7613b49ae381304f540c58b4ad4 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 79 2.4E-14 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_13195 6dcbe7613b49ae381304f540c58b4ad4 101 SUPERFAMILY SSF52794 1 100 1.15E-24 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_13195 6dcbe7613b49ae381304f540c58b4ad4 101 Gene3D G3DSA:3.40.50.2300 1 101 2.0E-27 T 15-10-2018 C2I28_05720 458cc6a00e6609bf3c19b194fa22eae0 216 SUPERFAMILY SSF53335 8 207 1.23E-31 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_05720 458cc6a00e6609bf3c19b194fa22eae0 216 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.939 T 15-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 C2I28_05720 458cc6a00e6609bf3c19b194fa22eae0 216 Gene3D G3DSA:3.40.50.150 1 211 1.5E-75 T 15-10-2018 C2I28_05720 458cc6a00e6609bf3c19b194fa22eae0 216 Pfam PF02390 Putative methyltransferase 39 207 1.1E-50 T 15-10-2018 C2I28_05720 458cc6a00e6609bf3c19b194fa22eae0 216 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 25 211 2.4E-63 T 15-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 C2I28_22290 ef68bd87634a692307c78d850738df74 343 Pfam PF00107 Zinc-binding dehydrogenase 170 297 1.0E-21 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_22290 ef68bd87634a692307c78d850738df74 343 SMART SM00829 4 334 0.0048 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_22290 ef68bd87634a692307c78d850738df74 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 127 1.1E-32 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_22290 ef68bd87634a692307c78d850738df74 343 SUPERFAMILY SSF50129 1 169 5.17E-46 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_22290 ef68bd87634a692307c78d850738df74 343 Gene3D G3DSA:3.90.180.10 19 324 1.9E-96 T 15-10-2018 C2I28_22290 ef68bd87634a692307c78d850738df74 343 SUPERFAMILY SSF51735 134 301 1.51E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_22290 ef68bd87634a692307c78d850738df74 343 Gene3D G3DSA:3.40.50.720 148 281 1.9E-96 T 15-10-2018 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 137 168 - T 15-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 SUPERFAMILY SSF56327 169 434 6.78E-91 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 Gene3D G3DSA:3.90.110.10 167 438 6.4E-101 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 Gene3D G3DSA:3.40.50.720 1 166 5.8E-69 T 15-10-2018 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 163 174 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 189 201 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 73 89 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 108 128 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 137 154 7.6E-49 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 193 408 1.4E-49 T 15-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 Pfam PF02056 Family 4 glycosyl hydrolase 2 183 9.8E-70 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_13210 799a4a9770f0630f9250cbf58ecb462c 438 SUPERFAMILY SSF51735 1 164 2.19E-54 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_26615 74c963706102ace96dc15b63eb375579 173 Pfam PF12796 Ankyrin repeats (3 copies) 23 111 1.1E-16 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_26615 74c963706102ace96dc15b63eb375579 173 Pfam PF12796 Ankyrin repeats (3 copies) 113 167 1.6E-11 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_26615 74c963706102ace96dc15b63eb375579 173 SMART SM00248 48 77 5.8E-4 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 SMART SM00248 81 110 1.6E-5 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 SMART SM00248 147 173 2900.0 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 SMART SM00248 15 44 1700.0 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 SMART SM00248 114 143 2.3E-4 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 PRINTS PR01415 Ankyrin repeat signature 97 111 6.5E-6 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 PRINTS PR01415 Ankyrin repeat signature 49 64 6.5E-6 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_26615 74c963706102ace96dc15b63eb375579 173 Gene3D G3DSA:1.25.40.960 119 170 3.8E-17 T 15-10-2018 C2I28_26615 74c963706102ace96dc15b63eb375579 173 SUPERFAMILY SSF48403 14 167 2.75E-48 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_26615 74c963706102ace96dc15b63eb375579 173 Gene3D G3DSA:1.25.40.20 1 118 4.1E-34 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_25810 74df7aba70e4d8134d75ff31d3e85ff7 135 Pfam PF08877 MepB protein 3 113 7.9E-42 T 15-10-2018 IPR011235 MepB-like C2I28_25810 74df7aba70e4d8134d75ff31d3e85ff7 135 Gene3D G3DSA:3.40.1350.140 1 126 3.2E-45 T 15-10-2018 IPR038231 MepB-like superfamily C2I28_25810 74df7aba70e4d8134d75ff31d3e85ff7 135 PIRSF PIRSF032285 1 130 8.8E-51 T 15-10-2018 IPR011235 MepB-like C2I28_19270 cdc1f496e67b05eb426dfcadcd5a064d 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 42 306 9.0E-50 T 15-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I28_19270 cdc1f496e67b05eb426dfcadcd5a064d 314 Gene3D G3DSA:3.40.190.120 142 251 7.8E-76 T 15-10-2018 C2I28_19270 cdc1f496e67b05eb426dfcadcd5a064d 314 SUPERFAMILY SSF53850 43 312 8.32E-49 T 15-10-2018 C2I28_19270 cdc1f496e67b05eb426dfcadcd5a064d 314 Gene3D G3DSA:3.40.190.10 44 306 7.8E-76 T 15-10-2018 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 Pfam PF00294 pfkB family carbohydrate kinase 1 284 3.8E-73 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_12800 c416e7810a2a80179e63c986d253788a 292 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 290 3.7E-107 T 15-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 Gene3D G3DSA:3.40.1190.20 1 292 1.5E-91 T 15-10-2018 IPR029056 Ribokinase-like C2I28_12800 c416e7810a2a80179e63c986d253788a 292 SUPERFAMILY SSF53613 3 290 2.03E-78 T 15-10-2018 IPR029056 Ribokinase-like C2I28_12800 c416e7810a2a80179e63c986d253788a 292 Hamap MF_01987 Ribokinase [rbsK]. 2 291 24.754 T 15-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 PRINTS PR00990 Ribokinase signature 6 27 1.5E-33 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 PRINTS PR00990 Ribokinase signature 33 52 1.5E-33 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 PRINTS PR00990 Ribokinase signature 207 218 1.5E-33 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 PRINTS PR00990 Ribokinase signature 172 187 1.5E-33 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_12800 c416e7810a2a80179e63c986d253788a 292 PRINTS PR00990 Ribokinase signature 104 117 1.5E-33 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 95 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 Gene3D G3DSA:1.20.1250.20 14 237 3.8E-64 T 15-10-2018 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 ProSitePatterns PS00216 Sugar transport proteins signature 1. 319 336 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 13 456 8.2E-118 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 PRINTS PR00171 Sugar transporter signature 384 396 1.8E-22 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 PRINTS PR00171 Sugar transporter signature 32 42 1.8E-22 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 PRINTS PR00171 Sugar transporter signature 115 134 1.8E-22 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 PRINTS PR00171 Sugar transporter signature 361 382 1.8E-22 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 PRINTS PR00171 Sugar transporter signature 275 285 1.8E-22 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 Gene3D G3DSA:1.20.1250.20 240 461 3.2E-67 T 15-10-2018 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 Pfam PF00083 Sugar (and other) transporter 27 460 6.4E-114 T 15-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 C2I28_07755 f20ffb5f1afdcf6cdb2e30b595251675 461 SUPERFAMILY SSF103473 19 457 3.14E-78 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 Gene3D G3DSA:3.40.309.10 252 442 2.0E-186 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 Gene3D G3DSA:3.40.605.10 12 465 2.0E-186 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 21 468 1.8E-202 T 15-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 PIRSF PIRSF036492 25 471 1.3E-88 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 Pfam PF00171 Aldehyde dehydrogenase family 12 469 8.3E-180 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_15285 01897b5dbcdd985ba0d52116291e28b4 474 SUPERFAMILY SSF53720 2 473 3.93E-177 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 Gene3D G3DSA:3.40.50.2000 557 740 7.8E-88 T 15-10-2018 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 Gene3D G3DSA:3.40.50.2000 377 756 7.8E-88 T 15-10-2018 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 Gene3D G3DSA:3.20.110.10 6 207 4.0E-19 T 15-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 Pfam PF03065 Glycosyl hydrolase family 57 32 258 1.0E-9 T 15-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 SUPERFAMILY SSF88713 25 182 1.17E-10 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 SUPERFAMILY SSF53756 375 759 3.62E-89 T 15-10-2018 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 Pfam PF00534 Glycosyl transferases group 1 574 738 3.7E-38 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_04100 b9f4b94855a5e968e3f6d19f4ce5bab7 772 Pfam PF13439 Glycosyltransferase Family 4 387 559 1.7E-31 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_23450 0bdcfabc3312acc2796866eeac769e03 61 Gene3D G3DSA:1.20.58.990 11 60 1.3E-9 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_23450 0bdcfabc3312acc2796866eeac769e03 61 SUPERFAMILY SSF140500 14 60 2.75E-12 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_23450 0bdcfabc3312acc2796866eeac769e03 61 Pfam PF09388 Spo0E like sporulation regulatory protein 16 56 2.1E-12 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 Pfam PF00005 ABC transporter 352 501 9.0E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 SUPERFAMILY SSF90123 5 320 9.16E-74 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 Gene3D G3DSA:3.40.50.300 325 576 1.4E-83 T 15-10-2018 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 Gene3D G3DSA:1.20.1560.10 1 316 7.4E-90 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 Pfam PF00664 ABC transporter transmembrane region 20 287 1.5E-46 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 SMART SM00382 361 547 4.4E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12705 a51be9baad257b59dc0d43dd7083b0aa 580 SUPERFAMILY SSF52540 326 571 7.21E-82 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_25740 18b895e77b6761f0704eca6c4df744d2 488 Gene3D G3DSA:3.40.605.10 28 483 9.1E-167 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_25740 18b895e77b6761f0704eca6c4df744d2 488 SUPERFAMILY SSF53720 9 487 8.9E-158 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_25740 18b895e77b6761f0704eca6c4df744d2 488 Pfam PF00171 Aldehyde dehydrogenase family 18 484 7.2E-167 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_25740 18b895e77b6761f0704eca6c4df744d2 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_25740 18b895e77b6761f0704eca6c4df744d2 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_25740 18b895e77b6761f0704eca6c4df744d2 488 Gene3D G3DSA:3.40.309.10 258 456 9.1E-167 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_11710 d9ebcbc17208743a0270dd461daa488d 308 Gene3D G3DSA:1.10.3720.10 95 308 4.8E-23 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11710 d9ebcbc17208743a0270dd461daa488d 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 308 2.9E-34 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_11710 d9ebcbc17208743a0270dd461daa488d 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 83 1.4E-16 T 15-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I28_11710 d9ebcbc17208743a0270dd461daa488d 308 SUPERFAMILY SSF161098 102 288 6.28E-28 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18255 4cae34d9b0a909b80d550bc3fdfc4276 202 Gene3D G3DSA:3.40.50.150 23 164 3.5E-13 T 15-10-2018 C2I28_18255 4cae34d9b0a909b80d550bc3fdfc4276 202 Pfam PF13679 Methyltransferase domain 46 103 1.6E-7 T 15-10-2018 IPR025714 Methyltransferase domain C2I28_18255 4cae34d9b0a909b80d550bc3fdfc4276 202 SUPERFAMILY SSF53335 23 130 4.97E-15 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_19855 86e49ec3bfceb18488459cb8de6dbb99 133 Gene3D G3DSA:3.10.129.10 1 132 1.8E-35 T 15-10-2018 C2I28_19855 86e49ec3bfceb18488459cb8de6dbb99 133 Pfam PF13279 Thioesterase-like superfamily 8 124 1.7E-16 T 15-10-2018 C2I28_19855 86e49ec3bfceb18488459cb8de6dbb99 133 SUPERFAMILY SSF54637 1 129 2.11E-37 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_14080 8da3db58fa4d950c9ff8293e2e0f0f0f 537 Pfam PF01546 Peptidase family M20/M25/M40 83 492 3.1E-12 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_14080 8da3db58fa4d950c9ff8293e2e0f0f0f 537 Gene3D G3DSA:3.40.630.10 8 232 3.6E-39 T 15-10-2018 C2I28_14080 8da3db58fa4d950c9ff8293e2e0f0f0f 537 PIRSF PIRSF010386 3 536 7.7E-199 T 15-10-2018 IPR012166 Uncharacterised protein family RocB C2I28_14080 8da3db58fa4d950c9ff8293e2e0f0f0f 537 SUPERFAMILY SSF53187 10 519 3.14E-33 T 15-10-2018 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 Gene3D G3DSA:3.30.479.20 155 273 8.3E-44 T 15-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 4.5E-119 T 15-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 Gene3D G3DSA:1.10.286.20 193 239 8.3E-44 T 15-10-2018 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 SUPERFAMILY SSF54713 151 292 2.22E-53 T 15-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 15-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 15-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 Gene3D G3DSA:1.10.8.10 1 55 1.6E-28 T 15-10-2018 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 Gene3D G3DSA:3.30.479.20 56 146 1.1E-23 T 15-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 SUPERFAMILY SSF54713 55 143 2.35E-22 T 15-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 Pfam PF00889 Elongation factor TS 70 274 6.4E-76 T 15-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.418 T 15-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 C2I28_02385 c3b7612b976cf17bfe3bfe35e3504154 293 SUPERFAMILY SSF46934 3 54 1.99E-21 T 15-10-2018 IPR009060 UBA-like superfamily GO:0005515 C2I28_18700 37bbf53c59925171d5ee081a84acf796 261 Pfam PF00005 ABC transporter 17 167 2.2E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_18700 37bbf53c59925171d5ee081a84acf796 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_18700 37bbf53c59925171d5ee081a84acf796 261 SUPERFAMILY SSF52540 2 234 2.18E-54 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18700 37bbf53c59925171d5ee081a84acf796 261 Gene3D G3DSA:3.40.50.300 1 256 9.5E-67 T 15-10-2018 C2I28_18700 37bbf53c59925171d5ee081a84acf796 261 SMART SM00382 26 218 8.0E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Gene3D G3DSA:3.30.450.20 2 116 1.2E-10 T 15-10-2018 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00267 376 548 1.5E-43 T 15-10-2018 IPR000160 GGDEF domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Pfam PF13426 PAS domain 19 115 1.1E-4 T 15-10-2018 IPR000014 PAS domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00086 206 248 3.2E-7 T 15-10-2018 IPR001610 PAC motif C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00086 78 119 350.0 T 15-10-2018 IPR001610 PAC motif C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00086 334 376 6.9E-5 T 15-10-2018 IPR001610 PAC motif C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Pfam PF00563 EAL domain 566 799 1.5E-75 T 15-10-2018 IPR001633 EAL domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Gene3D G3DSA:3.30.70.270 381 561 9.7E-48 T 15-10-2018 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SUPERFAMILY SSF55785 245 374 8.03E-18 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Gene3D G3DSA:3.20.20.450 562 813 5.6E-94 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SUPERFAMILY SSF141868 564 812 1.07E-84 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00052 558 804 5.3E-97 T 15-10-2018 IPR001633 EAL domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SUPERFAMILY SSF55073 393 549 5.18E-40 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 384 545 1.2E-32 T 15-10-2018 IPR000160 GGDEF domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SUPERFAMILY SSF55785 140 249 5.76E-16 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Gene3D G3DSA:2.10.70.100 203 249 2.2E-12 T 15-10-2018 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Pfam PF08447 PAS fold 284 370 8.0E-18 T 15-10-2018 IPR013655 PAS fold-3 GO:0005515 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Pfam PF08447 PAS fold 154 242 1.7E-14 T 15-10-2018 IPR013655 PAS fold-3 GO:0005515 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Pfam PF00990 Diguanylate cyclase, GGDEF domain 387 543 1.3E-38 T 15-10-2018 IPR000160 GGDEF domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Gene3D G3DSA:3.30.450.20 127 200 9.5E-12 T 15-10-2018 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 Gene3D G3DSA:3.30.450.20 252 374 8.5E-28 T 15-10-2018 C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00091 260 329 1.2E-6 T 15-10-2018 IPR000014 PAS domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SMART SM00091 8 73 3.2E-4 T 15-10-2018 IPR000014 PAS domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 141 255 1.6E-5 T 15-10-2018 IPR000014 PAS domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 121 6.2E-6 T 15-10-2018 IPR000014 PAS domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 256 380 9.9E-12 T 15-10-2018 IPR000014 PAS domain C2I28_13570 66b88a06984fe1e5883741ff12c85f64 814 SUPERFAMILY SSF55785 12 115 2.97E-10 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 Pfam PF04542 Sigma-70 region 2 23 84 1.7E-13 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 174 1.1E-27 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 Gene3D G3DSA:1.10.10.10 98 178 6.5E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 Gene3D G3DSA:1.10.1740.10 4 97 1.2E-20 T 15-10-2018 C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 SUPERFAMILY SSF88659 111 177 1.53E-17 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 Pfam PF08281 Sigma-70, region 4 119 171 1.3E-14 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_22715 e53aaddec7b0d6067936cfdc3472dfe4 178 SUPERFAMILY SSF88946 15 97 5.23E-19 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02165 babf8374ad3035944c503c464c23f092 413 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 164 2.5E-31 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_02165 babf8374ad3035944c503c464c23f092 413 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 413 163.414 T 15-10-2018 IPR008135 Competence-induced protein CinA C2I28_02165 babf8374ad3035944c503c464c23f092 413 PIRSF PIRSF006728 1 413 1.8E-158 T 15-10-2018 IPR008135 Competence-induced protein CinA C2I28_02165 babf8374ad3035944c503c464c23f092 413 Gene3D G3DSA:3.90.950.20 243 412 1.2E-51 T 15-10-2018 IPR036653 CinA-like, C-terminal C2I28_02165 babf8374ad3035944c503c464c23f092 413 SUPERFAMILY SSF53218 1 207 1.44E-40 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_02165 babf8374ad3035944c503c464c23f092 413 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 265 409 5.3E-40 T 15-10-2018 IPR008136 CinA, C-terminal C2I28_02165 babf8374ad3035944c503c464c23f092 413 Gene3D G3DSA:3.40.980.10 1 196 1.3E-49 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_02165 babf8374ad3035944c503c464c23f092 413 SMART SM00852 5 171 7.2E-40 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_02165 babf8374ad3035944c503c464c23f092 413 SUPERFAMILY SSF142433 251 412 1.57E-47 T 15-10-2018 IPR036653 CinA-like, C-terminal C2I28_02165 babf8374ad3035944c503c464c23f092 413 Pfam PF02464 Competence-damaged protein 258 410 1.7E-49 T 15-10-2018 IPR008136 CinA, C-terminal C2I28_02165 babf8374ad3035944c503c464c23f092 413 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 412 1.1E-151 T 15-10-2018 IPR008135 Competence-induced protein CinA C2I28_02165 babf8374ad3035944c503c464c23f092 413 Pfam PF00994 Probable molybdopterin binding domain 6 169 1.8E-32 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_21930 df77e7b02102c659bd6134445d600d57 542 Gene3D G3DSA:3.40.50.300 92 225 3.7E-27 T 15-10-2018 C2I28_21930 df77e7b02102c659bd6134445d600d57 542 Gene3D G3DSA:3.40.50.300 250 502 5.6E-52 T 15-10-2018 C2I28_21930 df77e7b02102c659bd6134445d600d57 542 Pfam PF00005 ABC transporter 23 67 4.8E-10 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_21930 df77e7b02102c659bd6134445d600d57 542 Pfam PF00005 ABC transporter 304 428 5.5E-21 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_21930 df77e7b02102c659bd6134445d600d57 542 Pfam PF12848 ABC transporter 164 227 4.4E-7 T 15-10-2018 IPR032781 ABC-transporter extension domain C2I28_21930 df77e7b02102c659bd6134445d600d57 542 SUPERFAMILY SSF52540 3 188 6.78E-35 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21930 df77e7b02102c659bd6134445d600d57 542 SUPERFAMILY SSF52540 294 472 6.62E-39 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21930 df77e7b02102c659bd6134445d600d57 542 Gene3D G3DSA:3.40.50.300 2 91 4.7E-14 T 15-10-2018 C2I28_21930 df77e7b02102c659bd6134445d600d57 542 SMART SM00382 312 472 7.6E-9 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_21930 df77e7b02102c659bd6134445d600d57 542 SMART SM00382 28 169 2.5E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_23720 4436b8e5150051189af22a6d5fd8928a 275 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 53 196 8.4E-49 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_23720 4436b8e5150051189af22a6d5fd8928a 275 Gene3D G3DSA:1.10.260.150 24 275 7.5E-86 T 15-10-2018 C2I28_23720 4436b8e5150051189af22a6d5fd8928a 275 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 54 195 1.4E-48 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_18145 b62fd2cd003853acb3c03b261778a5c9 236 SUPERFAMILY SSF161098 15 213 9.16E-35 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18145 b62fd2cd003853acb3c03b261778a5c9 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 88 2.9E-14 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_18145 b62fd2cd003853acb3c03b261778a5c9 236 Gene3D G3DSA:1.10.3720.10 2 229 2.7E-43 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18145 b62fd2cd003853acb3c03b261778a5c9 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 228 3.3E-16 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 15-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.7E-53 T 15-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 15-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 SUPERFAMILY SSF54686 1 137 1.96E-59 T 15-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.8E-63 T 15-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 Gene3D G3DSA:3.90.1170.10 1 143 1.1E-55 T 15-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.4E-40 T 15-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.4E-40 T 15-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.4E-40 T 15-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.4E-40 T 15-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08720 6a508786dba87f5d827bffc095f94c57 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.202 T 15-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_23180 68b8cc47bbd4bf85626d0840b234937f 104 Gene3D G3DSA:3.30.70.930 1 103 4.3E-37 T 15-10-2018 IPR029756 MTH1187/YkoF-like C2I28_23180 68b8cc47bbd4bf85626d0840b234937f 104 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 101 1.6E-34 T 15-10-2018 IPR002767 Thiamine-binding protein C2I28_23180 68b8cc47bbd4bf85626d0840b234937f 104 SUPERFAMILY SSF89957 1 102 4.45E-31 T 15-10-2018 IPR029756 MTH1187/YkoF-like C2I28_23180 68b8cc47bbd4bf85626d0840b234937f 104 Pfam PF01910 Thiamine-binding protein 4 98 1.1E-33 T 15-10-2018 IPR002767 Thiamine-binding protein C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 SUPERFAMILY SSF51430 7 275 2.36E-91 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 Gene3D G3DSA:3.20.20.100 1 280 3.0E-125 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PRINTS PR00069 Aldo-keto reductase signature 100 118 3.9E-50 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PRINTS PR00069 Aldo-keto reductase signature 164 193 3.9E-50 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PRINTS PR00069 Aldo-keto reductase signature 130 147 3.9E-50 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PRINTS PR00069 Aldo-keto reductase signature 201 225 3.9E-50 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PRINTS PR00069 Aldo-keto reductase signature 40 64 3.9E-50 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 Pfam PF00248 Aldo/keto reductase family 31 266 5.6E-49 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PIRSF PIRSF000097 120 277 3.1E-52 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 PIRSF PIRSF000097 2 125 1.0E-41 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_13450 413de58c209cb8c21dcc557e453d4dfe 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 Pfam PF00425 chorismate binding enzyme 199 452 5.9E-99 T 15-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 PRINTS PR00095 Anthranilate synthase component I signature 409 423 1.7E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 PRINTS PR00095 Anthranilate synthase component I signature 300 313 1.7E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 PRINTS PR00095 Anthranilate synthase component I signature 314 327 1.7E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 PRINTS PR00095 Anthranilate synthase component I signature 394 408 1.7E-20 T 15-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 Pfam PF04715 Anthranilate synthase component I, N terminal region 22 150 1.1E-30 T 15-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 103 454 2.0E-99 T 15-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 SUPERFAMILY SSF56322 18 459 1.83E-141 T 15-10-2018 IPR005801 ADC synthase GO:0009058 C2I28_08480 1a325c3d365e7840271c9f998c9ebb68 471 Gene3D G3DSA:3.60.120.10 2 470 1.4E-161 T 15-10-2018 IPR005801 ADC synthase GO:0009058 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 Pfam PF02378 Phosphotransferase system, EIIC 13 347 9.9E-95 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 507 3.3E-253 T 15-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 445 462 - T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 406 491 1.7E-24 T 15-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 Gene3D G3DSA:2.70.70.10 525 684 1.4E-63 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_14550 58e9a365998d9f71654841d8faeec090 684 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 358 3.7E-91 T 15-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 Gene3D G3DSA:3.30.1360.60 428 508 1.1E-27 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 SUPERFAMILY SSF55604 433 506 7.59E-21 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 536 658 1.1E-53 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 Pfam PF00367 phosphotransferase system, EIIB 435 467 1.9E-12 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 SUPERFAMILY SSF51261 534 679 3.31E-55 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_14550 58e9a365998d9f71654841d8faeec090 684 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 599 611 - T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_14550 58e9a365998d9f71654841d8faeec090 684 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 537 657 2.2E-48 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1181 1316 1.3E-8 T 15-10-2018 C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 Gene3D G3DSA:2.60.40.10 978 1062 6.9E-16 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 Gene3D G3DSA:2.60.40.10 1067 1152 6.3E-14 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SUPERFAMILY SSF49899 1160 1321 1.83E-13 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SUPERFAMILY SSF51126 131 618 2.9E-13 T 15-10-2018 IPR011050 Pectin lyase fold/virulence factor C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 906 971 4.7E-19 T 15-10-2018 C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00060 1069 1142 2.9E-5 T 15-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00060 981 1052 1.6E-5 T 15-10-2018 IPR003961 Fibronectin type III GO:0005515 C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 421 443 2.9 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 504 525 3600.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 527 549 31.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 383 404 3600.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 223 257 4600.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 722 750 4600.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 880 914 5000.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 444 482 1400.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SMART SM00710 809 831 6900.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SUPERFAMILY SSF49265 1061 1140 1.78E-10 T 15-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I28_18945 2188442bd47e09769f94a454f7ade81f 1324 SUPERFAMILY SSF49265 973 1060 1.04E-9 T 15-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 102 6.2E-38 T 15-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 SUPERFAMILY SSF51735 4 168 5.53E-62 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05355 0825662e122dbd304e0d920702d2afac 343 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 2.7E-67 T 15-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 SMART SM00846 3 152 3.7E-88 T 15-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 Gene3D G3DSA:3.40.50.720 4 329 4.8E-152 T 15-10-2018 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.1E-40 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.1E-40 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.1E-40 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 4.1E-40 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.1E-40 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.4E-133 T 15-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 PIRSF PIRSF000149 1 335 1.7E-138 T 15-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 Gene3D G3DSA:3.30.360.10 151 315 4.8E-152 T 15-10-2018 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 SUPERFAMILY SSF55347 152 314 1.52E-71 T 15-10-2018 C2I28_05355 0825662e122dbd304e0d920702d2afac 343 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 15-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 Gene3D G3DSA:3.40.50.300 167 454 5.7E-119 T 15-10-2018 C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 SUPERFAMILY SSF52540 183 433 1.35E-55 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 442 1.9E-187 T 15-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 SUPERFAMILY SSF48024 8 119 4.84E-37 T 15-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 1.8E-119 T 15-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.2E-33 T 15-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 C2I28_07905 aea08033e225c2f0a7dc2fbe53cf54f5 454 Gene3D G3DSA:1.10.860.10 1 166 7.9E-65 T 15-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal C2I28_00075 1dd8dac4f9da383a94271b3a4450f632 459 Pfam PF03611 PTS system sugar-specific permease component 10 408 4.8E-139 T 15-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 C2I28_26185 1dd8dac4f9da383a94271b3a4450f632 459 Pfam PF03611 PTS system sugar-specific permease component 10 408 4.8E-139 T 15-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 C2I28_08345 90b43649ed57ab42be881af483cbcbd5 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 15-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 C2I28_08345 90b43649ed57ab42be881af483cbcbd5 125 SUPERFAMILY SSF55298 2 124 2.04E-49 T 15-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 C2I28_08345 90b43649ed57ab42be881af483cbcbd5 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 122 1.1E-54 T 15-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 C2I28_08345 90b43649ed57ab42be881af483cbcbd5 125 Gene3D G3DSA:3.30.1330.40 2 124 5.9E-55 T 15-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 C2I28_08345 90b43649ed57ab42be881af483cbcbd5 125 Pfam PF01042 Endoribonuclease L-PSP 6 122 3.9E-47 T 15-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 C2I28_14245 7c9612479babde547b802312eae6f8c1 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 19 276 1.1E-74 T 15-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 C2I28_14245 7c9612479babde547b802312eae6f8c1 276 Gene3D G3DSA:3.40.50.620 2 276 4.8E-77 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_14245 7c9612479babde547b802312eae6f8c1 276 Pfam PF02540 NAD synthase 24 267 7.2E-72 T 15-10-2018 IPR022310 NAD/GMP synthase C2I28_14245 7c9612479babde547b802312eae6f8c1 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 19 270 47.655 T 15-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 C2I28_14245 7c9612479babde547b802312eae6f8c1 276 SUPERFAMILY SSF52402 4 275 1.09E-83 T 15-10-2018 C2I28_02890 35e28569c2ce079fda587faf990a4a91 257 SMART SM00363 181 243 4.2E-11 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_02890 35e28569c2ce079fda587faf990a4a91 257 Gene3D G3DSA:3.10.290.10 180 233 1.1E-10 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_02890 35e28569c2ce079fda587faf990a4a91 257 Gene3D G3DSA:3.30.1370.160 2 79 1.0E-29 T 15-10-2018 C2I28_02890 35e28569c2ce079fda587faf990a4a91 257 Pfam PF01479 S4 domain 181 226 3.8E-8 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_02890 35e28569c2ce079fda587faf990a4a91 257 Gene3D G3DSA:3.30.70.330 80 165 1.4E-27 T 15-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily C2I28_02890 35e28569c2ce079fda587faf990a4a91 257 SUPERFAMILY SSF55174 35 253 8.24E-33 T 15-10-2018 C2I28_04065 cd85ca0d8c95901fca0758198a4e5276 322 Gene3D G3DSA:3.30.420.40 130 303 1.3E-106 T 15-10-2018 C2I28_04065 cd85ca0d8c95901fca0758198a4e5276 322 Pfam PF00480 ROK family 7 319 8.5E-73 T 15-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_04065 cd85ca0d8c95901fca0758198a4e5276 322 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 320 9.0E-122 T 15-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 C2I28_04065 cd85ca0d8c95901fca0758198a4e5276 322 ProSitePatterns PS01125 ROK family signature. 139 166 - T 15-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_04065 cd85ca0d8c95901fca0758198a4e5276 322 SUPERFAMILY SSF53067 5 320 2.03E-71 T 15-10-2018 C2I28_04065 cd85ca0d8c95901fca0758198a4e5276 322 Gene3D G3DSA:3.30.420.40 7 315 1.3E-106 T 15-10-2018 C2I28_05175 cb04ddac7633a07ff10ef8b90c759c36 202 Gene3D G3DSA:1.20.1300.10 2 202 1.4E-45 T 15-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05175 cb04ddac7633a07ff10ef8b90c759c36 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 92 193 6.7E-14 T 15-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05175 cb04ddac7633a07ff10ef8b90c759c36 202 SUPERFAMILY SSF81343 4 201 6.67E-59 T 15-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05175 cb04ddac7633a07ff10ef8b90c759c36 202 PIRSF PIRSF000170 1 202 1.4E-102 T 15-10-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute C2I28_05175 cb04ddac7633a07ff10ef8b90c759c36 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 201 3.0E-54 T 15-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 Pfam PF03734 L,D-transpeptidase catalytic domain 56 162 1.7E-15 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 Gene3D G3DSA:2.40.440.10 48 163 3.0E-40 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 SUPERFAMILY SSF54106 2 46 3.66E-9 T 15-10-2018 C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 Gene3D G3DSA:3.10.350.10 1 46 4.6E-10 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 Pfam PF01476 LysM domain 3 46 3.6E-10 T 15-10-2018 IPR018392 LysM domain C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 SUPERFAMILY SSF141523 55 163 4.71E-31 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_14630 d37424ffbd58803b8dc18a98c4836376 170 SMART SM00257 2 46 1.2E-8 T 15-10-2018 IPR018392 LysM domain C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 Gene3D G3DSA:1.20.1480.50 167 252 3.6E-19 T 15-10-2018 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 SUPERFAMILY SSF55874 313 480 2.1E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 Pfam PF00672 HAMP domain 197 245 4.1E-14 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 Gene3D G3DSA:3.30.565.10 330 490 3.3E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 322 6.0E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 SUPERFAMILY SSF158472 197 247 9.02E-13 T 15-10-2018 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 SMART SM00304 197 249 1.4E-15 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 SMART SM00388 257 324 6.6E-15 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 SUPERFAMILY SSF47384 244 323 6.87E-16 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 Gene3D G3DSA:1.10.287.130 253 323 2.5E-17 T 15-10-2018 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 5.9E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 481 5.9E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 5.9E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 5.9E-18 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 SMART SM00387 371 484 2.5E-37 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_21125 42afb94908e8b0e00a69993bd054eb99 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 372 481 1.0E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 5.5E-44 T 15-10-2018 IPR017932 Glutamine amidotransferase type 2 domain C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 PIRSF PIRSF001589 1 608 4.0E-141 T 15-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 Pfam PF00733 Asparagine synthase 243 579 7.3E-94 T 15-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 SUPERFAMILY SSF52402 231 577 6.55E-72 T 15-10-2018 C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 Gene3D G3DSA:3.60.20.10 2 182 1.4E-60 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 5.2E-165 T 15-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 C2I28_11430 a4983734bb4ca6d4a28c00a75513077b 615 SUPERFAMILY SSF56235 1 226 1.54E-62 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 SUPERFAMILY SSF48498 80 191 2.08E-9 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 SUPERFAMILY SSF46689 6 80 1.15E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.5E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.5E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 Gene3D G3DSA:1.10.357.10 2 192 1.4E-64 T 15-10-2018 C2I28_12495 e5880be238e65f2223d7ba1847875c02 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 3.0E-18 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 269 25.648 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 PIRSF PIRSF000193 5 272 2.3E-76 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 SUPERFAMILY SSF48179 164 272 6.97E-33 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 165 268 1.2E-34 T 15-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 Gene3D G3DSA:3.40.50.720 2 167 5.2E-48 T 15-10-2018 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 102 2.3E-20 T 15-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 SUPERFAMILY SSF51735 6 163 1.03E-28 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 268 8.0E-83 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_03635 f96cc6d23c060cc47f556045946d7155 282 Gene3D G3DSA:1.10.3730.10 168 273 6.1E-39 T 15-10-2018 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 SMART SM00478 39 187 1.7E-67 T 15-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 SUPERFAMILY SSF48150 1 210 9.26E-76 T 15-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 2.3E-5 T 15-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 Gene3D G3DSA:1.10.1670.10 16 205 2.3E-82 T 15-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 TIGRFAM TIGR01083 nth: endonuclease III 5 196 6.8E-87 T 15-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 Gene3D G3DSA:1.10.340.30 22 133 2.3E-82 T 15-10-2018 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.971 T 15-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 Pfam PF00633 Helix-hairpin-helix motif 100 128 2.3E-9 T 15-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 SMART SM00525 188 208 1.0E-4 T 15-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 3.7E-24 T 15-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 PIRSF PIRSF001435 1 213 7.8E-59 T 15-10-2018 C2I28_15045 bc1306347293afed5bb1287818c4fced 223 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 15-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 SUPERFAMILY SSF51735 11 256 2.68E-82 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 Gene3D G3DSA:3.40.50.720 1 257 3.4E-83 T 15-10-2018 C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 2.3E-62 T 15-10-2018 C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.2E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.2E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 2.2E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.2E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.2E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.2E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.1E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.1E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.1E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19830 64701481e7ca3dcc68978231fcf78523 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.8E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.8E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 SUPERFAMILY SSF51735 3 246 8.06E-74 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.0E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.0E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.0E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.0E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 Gene3D G3DSA:3.40.50.720 2 248 4.4E-75 T 15-10-2018 C2I28_23580 18c50fa5afd681acb44f8166ee1755b6 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 6.6E-58 T 15-10-2018 C2I28_13630 7b309ebcb20ea544fe43b6d8a4e09fac 267 Gene3D G3DSA:3.40.120.10 203 261 1.4E-5 T 15-10-2018 C2I28_13630 7b309ebcb20ea544fe43b6d8a4e09fac 267 Gene3D G3DSA:3.40.120.10 29 184 1.8E-43 T 15-10-2018 C2I28_13630 7b309ebcb20ea544fe43b6d8a4e09fac 267 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 177 3.9E-37 T 15-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13630 7b309ebcb20ea544fe43b6d8a4e09fac 267 SUPERFAMILY SSF53738 29 228 1.48E-43 T 15-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_13630 7b309ebcb20ea544fe43b6d8a4e09fac 267 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 15-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 Gene3D G3DSA:1.10.150.240 19 95 1.0E-62 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 Gene3D G3DSA:3.40.50.1000 7 197 1.0E-62 T 15-10-2018 IPR023214 HAD superfamily C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 71 191 5.9E-18 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 71 169 6.8E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 6 192 2.9E-75 T 15-10-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 191 1.1E-28 T 15-10-2018 C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 SUPERFAMILY SSF56784 7 210 2.0E-46 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_07660 62eaf0f976e51928be8532d591f5b133 235 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 7 191 9.0E-62 T 15-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase C2I28_14770 a76022c9c5f6c7385ad51ce14ae10f7a 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 364 1.1E-143 T 15-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 C2I28_14770 a76022c9c5f6c7385ad51ce14ae10f7a 371 Gene3D G3DSA:3.40.50.970 5 371 9.8E-124 T 15-10-2018 C2I28_14770 a76022c9c5f6c7385ad51ce14ae10f7a 371 Pfam PF00676 Dehydrogenase E1 component 54 343 2.4E-104 T 15-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I28_14770 a76022c9c5f6c7385ad51ce14ae10f7a 371 SUPERFAMILY SSF52518 10 366 1.49E-100 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_13370 c113bb38be4c2702df08518436dede06 657 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 651 1.9E-49 T 15-10-2018 IPR000160 GGDEF domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00091 5 80 69.0 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00091 121 189 4.8E-4 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00091 373 439 3.3E-4 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00091 249 316 0.57 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 Gene3D G3DSA:3.30.450.20 381 491 3.6E-23 T 15-10-2018 C2I28_13370 c113bb38be4c2702df08518436dede06 657 Gene3D G3DSA:3.30.450.20 246 365 8.0E-16 T 15-10-2018 C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00267 483 655 5.6E-63 T 15-10-2018 IPR000160 GGDEF domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 Gene3D G3DSA:3.30.70.270 492 657 1.9E-56 T 15-10-2018 C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00086 195 237 2.6 T 15-10-2018 IPR001610 PAC motif C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00086 441 483 5.0E-4 T 15-10-2018 IPR001610 PAC motif C2I28_13370 c113bb38be4c2702df08518436dede06 657 SMART SM00086 318 359 7.4 T 15-10-2018 IPR001610 PAC motif C2I28_13370 c113bb38be4c2702df08518436dede06 657 SUPERFAMILY SSF55073 499 656 1.33E-45 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_13370 c113bb38be4c2702df08518436dede06 657 Gene3D G3DSA:3.30.450.20 119 245 3.9E-24 T 15-10-2018 C2I28_13370 c113bb38be4c2702df08518436dede06 657 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 380 490 8.2E-15 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 247 366 1.1E-9 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 117 244 4.3E-20 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 SUPERFAMILY SSF55785 114 235 7.15E-19 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_13370 c113bb38be4c2702df08518436dede06 657 SUPERFAMILY SSF55785 386 485 3.66E-20 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_13370 c113bb38be4c2702df08518436dede06 657 Gene3D G3DSA:3.30.450.20 3 118 7.2E-8 T 15-10-2018 C2I28_13370 c113bb38be4c2702df08518436dede06 657 Pfam PF13426 PAS domain 261 357 3.9E-7 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 Pfam PF13426 PAS domain 385 482 7.3E-15 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 Pfam PF13426 PAS domain 132 236 5.6E-12 T 15-10-2018 IPR000014 PAS domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 491 653 2.3E-44 T 15-10-2018 IPR000160 GGDEF domain C2I28_13370 c113bb38be4c2702df08518436dede06 657 SUPERFAMILY SSF55785 234 357 4.01E-17 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 Gene3D G3DSA:3.30.1490.20 130 201 1.6E-146 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 SMART SM00878 335 440 7.7E-38 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 SUPERFAMILY SSF51246 332 443 1.2E-31 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 Pfam PF02785 Biotin carboxylase C-terminal domain 335 440 3.3E-30 T 15-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 SUPERFAMILY SSF52440 2 112 2.3E-42 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 Gene3D G3DSA:3.30.470.20 86 439 1.6E-146 T 15-10-2018 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 322 1.0E-75 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 SUPERFAMILY SSF56059 112 348 3.54E-69 T 15-10-2018 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 7.3E-41 T 15-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 C2I28_03020 fa3485301f4b7e41fb5799e27dac4c4c 450 Gene3D G3DSA:3.40.50.20 1 84 1.6E-32 T 15-10-2018 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 452 2.5E-189 T 15-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 542 554 - T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 Gene3D G3DSA:2.70.70.10 467 625 2.0E-57 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 395 412 - T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 Gene3D G3DSA:3.30.1360.60 382 457 6.8E-24 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 SUPERFAMILY SSF55604 382 456 8.63E-19 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 Pfam PF02378 Phosphotransferase system, EIIC 9 293 2.8E-79 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 482 600 2.1E-44 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 479 600 4.8E-50 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 SUPERFAMILY SSF51261 477 619 1.74E-51 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 Pfam PF00367 phosphotransferase system, EIIB 387 417 8.1E-12 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_13965 38ca9c5c0facddac8dd9e812d2bfd4ce 625 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 351 442 1.6E-17 T 15-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 15-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 SUPERFAMILY SSF46785 9 149 8.62E-33 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 Gene3D G3DSA:1.10.10.10 1 150 7.3E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 Pfam PF01047 MarR family 41 97 2.8E-17 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 SMART SM00347 33 133 9.2E-26 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.7E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.7E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_14355 1de86b8cb16069e32bdb43cae9bd7946 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.7E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 Gene3D G3DSA:2.30.30.280 214 277 8.3E-25 T 15-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 358 40.993 T 15-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 357 3.4E-143 T 15-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 Gene3D G3DSA:3.40.50.620 1 213 2.9E-98 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 SUPERFAMILY SSF52402 6 244 2.01E-58 T 15-10-2018 C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 Pfam PF03054 tRNA methyl transferase 9 357 8.7E-150 T 15-10-2018 C2I28_04635 e116b2b0a6303609aebbcc208de147ac 370 Gene3D G3DSA:2.40.30.10 279 370 7.4E-30 T 15-10-2018 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 Hamap MF_00740 Phosphopentomutase [deoB]. 5 389 56.559 T 15-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 Pfam PF01676 Metalloenzyme superfamily 6 379 3.7E-47 T 15-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 PIRSF PIRSF001491 4 393 1.3E-170 T 15-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 SUPERFAMILY SSF143856 102 218 5.36E-53 T 15-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 Gene3D G3DSA:3.40.720.10 6 389 1.1E-178 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 SUPERFAMILY SSF53649 4 392 7.85E-80 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 Gene3D G3DSA:3.30.70.1250 100 218 1.1E-178 T 15-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I28_03545 c7c7ffb02afc04cf73793d804f510b63 393 TIGRFAM TIGR01696 deoB: phosphopentomutase 7 387 4.9E-206 T 15-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 C2I28_03040 618f1960b837361a31da7d21aaad7ed9 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 5.4E-29 T 15-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_03040 618f1960b837361a31da7d21aaad7ed9 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.404 T 15-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_03040 618f1960b837361a31da7d21aaad7ed9 57 SUPERFAMILY SSF57829 1 55 2.99E-22 T 15-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 C2I28_03040 618f1960b837361a31da7d21aaad7ed9 57 Pfam PF01783 Ribosomal L32p protein family 2 57 4.1E-28 T 15-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_01175 efa8f36dcc5b06b1dcb68c7a45adc01d 314 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 231 4.7E-33 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_01175 efa8f36dcc5b06b1dcb68c7a45adc01d 314 Gene3D G3DSA:1.10.260.150 67 314 5.5E-78 T 15-10-2018 C2I28_01175 efa8f36dcc5b06b1dcb68c7a45adc01d 314 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 88 231 2.8E-48 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_05180 747531efc8bac3fcd645639c4edd9e16 175 Gene3D G3DSA:3.30.1380.20 5 164 7.8E-53 T 15-10-2018 C2I28_05180 747531efc8bac3fcd645639c4edd9e16 175 Pfam PF10702 Protein of unknown function (DUF2507) 36 157 2.0E-44 T 15-10-2018 IPR019642 Protein of unknown function DUF2507 C2I28_05180 747531efc8bac3fcd645639c4edd9e16 175 SUPERFAMILY SSF111126 32 141 1.2E-21 T 15-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily C2I28_04950 11b049d59708ee1d6f320c0c024e4b08 379 SMART SM00257 333 377 5.4E-7 T 15-10-2018 IPR018392 LysM domain C2I28_04950 11b049d59708ee1d6f320c0c024e4b08 379 Pfam PF01476 LysM domain 335 377 3.0E-9 T 15-10-2018 IPR018392 LysM domain C2I28_04950 11b049d59708ee1d6f320c0c024e4b08 379 Gene3D G3DSA:3.10.350.10 322 379 5.7E-11 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_04950 11b049d59708ee1d6f320c0c024e4b08 379 SUPERFAMILY SSF54106 333 378 1.44E-8 T 15-10-2018 C2I28_04950 11b049d59708ee1d6f320c0c024e4b08 379 TIGRFAM TIGR02907 spore_VI_D: stage VI sporulation protein D 9 377 1.8E-82 T 15-10-2018 IPR014256 Sporulation stage VI, protein D C2I28_15445 15f1c69dc3c000854586801744798fac 278 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 20 272 3.0E-63 T 15-10-2018 IPR015402 Protein of unknown function DUF1980 C2I28_15445 15f1c69dc3c000854586801744798fac 278 Pfam PF09323 Domain of unknown function (DUF1980) 1 182 6.7E-52 T 15-10-2018 IPR015402 Protein of unknown function DUF1980 C2I28_04590 363879f60b4476e5a819eb8dccf1a1d8 94 Hamap MF_01448 UPF0473 protein . 4 91 22.649 T 15-10-2018 IPR009711 Uncharacterised protein family UPF0473 C2I28_04590 363879f60b4476e5a819eb8dccf1a1d8 94 Pfam PF06949 Protein of unknown function (DUF1292) 13 90 1.6E-18 T 15-10-2018 IPR009711 Uncharacterised protein family UPF0473 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 158 1.1E-27 T 15-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 SUPERFAMILY SSF46557 7 79 7.06E-27 T 15-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 1.0E-31 T 15-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 Gene3D G3DSA:1.10.287.180 5 78 1.1E-31 T 15-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 15-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 SUPERFAMILY SSF54534 84 157 5.49E-22 T 15-10-2018 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 3.0E-58 T 15-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.752 T 15-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 Gene3D G3DSA:3.10.50.30 79 158 3.8E-27 T 15-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 C2I28_04560 01acfa5532c90d2d963a335b1aa08eb7 158 PIRSF PIRSF006092 1 158 7.9E-54 T 15-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 C2I28_21185 5816bf5674ade19ff1e8de7b7da6a582 233 Gene3D G3DSA:3.30.950.10 132 233 7.8E-13 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_21185 5816bf5674ade19ff1e8de7b7da6a582 233 PIRSF PIRSF036427 1 233 2.0E-79 T 15-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 C2I28_21185 5816bf5674ade19ff1e8de7b7da6a582 233 SUPERFAMILY SSF53790 1 232 6.8E-46 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_21185 5816bf5674ade19ff1e8de7b7da6a582 233 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 233 2.3E-87 T 15-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 C2I28_21185 5816bf5674ade19ff1e8de7b7da6a582 233 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 216 8.8E-49 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_21185 5816bf5674ade19ff1e8de7b7da6a582 233 Gene3D G3DSA:3.40.1010.10 2 131 9.1E-36 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_25235 322b357be65fae8e5e14f198bc1e0705 67 Gene3D G3DSA:1.10.260.40 3 66 7.3E-8 T 15-10-2018 C2I28_25235 322b357be65fae8e5e14f198bc1e0705 67 SUPERFAMILY SSF47413 4 59 9.98E-10 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_11080 d7c9f4f5162d72f496d2c39a4d131ef0 131 Pfam PF12732 YtxH-like protein 9 90 4.8E-8 T 15-10-2018 IPR024623 Uncharacterised protein family YtxH C2I28_11080 d7c9f4f5162d72f496d2c39a4d131ef0 131 Gene3D G3DSA:1.20.120.20 8 128 1.1E-5 T 15-10-2018 C2I28_16815 6e35bc91a688c291ac26bcbdfa888c62 167 SUPERFAMILY SSF109854 6 156 1.98E-27 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16815 6e35bc91a688c291ac26bcbdfa888c62 167 Gene3D G3DSA:1.20.120.450 2 160 2.1E-34 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16815 6e35bc91a688c291ac26bcbdfa888c62 167 Pfam PF05163 DinB family 6 163 1.0E-33 T 15-10-2018 IPR007837 DNA damage-inducible protein DinB C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 Gene3D G3DSA:3.30.460.20 1 132 1.5E-30 T 15-10-2018 C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 Pfam PF01544 CorA-like Mg2+ transporter protein 32 318 2.5E-64 T 15-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 SUPERFAMILY SSF143865 1 257 2.62E-62 T 15-10-2018 C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 Gene3D G3DSA:1.20.58.340 247 323 1.3E-15 T 15-10-2018 C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 12 320 1.8E-62 T 15-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 Gene3D G3DSA:1.20.58.340 133 246 8.7E-29 T 15-10-2018 C2I28_13920 85bf4ab8500aabfbd52daf03dab87f6c 323 SUPERFAMILY SSF144083 262 320 6.54E-15 T 15-10-2018 C2I28_12995 5374096f3c30c4d48ef29bb37a459afc 217 SUPERFAMILY SSF55469 11 213 4.84E-47 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_12995 5374096f3c30c4d48ef29bb37a459afc 217 Gene3D G3DSA:3.40.109.10 1 187 7.7E-52 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_12995 5374096f3c30c4d48ef29bb37a459afc 217 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 4 206 1.6E-71 T 15-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 C2I28_12995 5374096f3c30c4d48ef29bb37a459afc 217 Pfam PF00881 Nitroreductase family 16 182 1.6E-27 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 Gene3D G3DSA:3.40.50.10490 2 220 2.2E-80 T 15-10-2018 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 4 297 42.29 T 15-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 8 298 3.2E-131 T 15-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 Pfam PF01380 SIS domain 127 197 2.7E-10 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 SUPERFAMILY SSF53697 8 250 4.67E-70 T 15-10-2018 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 187 204 - T 15-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 C2I28_12580 f9ef16fec5a1c81bad658160a59a8d0f 301 Gene3D G3DSA:1.10.8.1080 221 299 4.3E-30 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 299 5.9E-59 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 434 9.9E-19 T 15-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.6E-18 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 4.6E-18 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 4.6E-18 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 4.6E-18 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 Gene3D G3DSA:3.50.50.60 116 442 2.9E-160 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 2.8E-29 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.8E-29 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 2.8E-29 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 2.8E-29 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 2.8E-29 T 15-10-2018 C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 SUPERFAMILY SSF51905 1 317 1.87E-43 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 Gene3D G3DSA:3.50.50.60 3 342 2.9E-160 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_14335 cb71df7670a9022e49328e7d464265f6 446 SUPERFAMILY SSF55424 325 445 2.75E-32 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_12320 9027b871d6db52ddd3d19bbd72017a07 187 Pfam PF02632 BioY family 27 173 1.2E-34 T 15-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I28_12320 9027b871d6db52ddd3d19bbd72017a07 187 Gene3D G3DSA:1.10.1760.20 1 179 1.8E-48 T 15-10-2018 C2I28_12320 9027b871d6db52ddd3d19bbd72017a07 187 PIRSF PIRSF016661 1 181 2.2E-49 T 15-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I28_05230 15ca95508d82caafee0e3632efe6b298 368 SUPERFAMILY SSF51726 12 368 1.7E-78 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_05230 15ca95508d82caafee0e3632efe6b298 368 Gene3D G3DSA:3.20.20.210 6 368 1.5E-126 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_05230 15ca95508d82caafee0e3632efe6b298 368 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 342 3.4E-16 T 15-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 C2I28_09630 0df5ec355f7cf032ab7a656631e58d93 271 SMART SM00079 49 271 2.4E-6 T 15-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I28_09630 0df5ec355f7cf032ab7a656631e58d93 271 SMART SM00062 49 270 3.7E-78 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_09630 0df5ec355f7cf032ab7a656631e58d93 271 Gene3D G3DSA:3.40.190.10 50 268 6.8E-85 T 15-10-2018 C2I28_09630 0df5ec355f7cf032ab7a656631e58d93 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 270 2.1E-59 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_09630 0df5ec355f7cf032ab7a656631e58d93 271 Gene3D G3DSA:3.40.190.10 137 234 6.8E-85 T 15-10-2018 C2I28_09630 0df5ec355f7cf032ab7a656631e58d93 271 SUPERFAMILY SSF53850 3 270 1.17E-70 T 15-10-2018 C2I28_13000 81c6bf55b115138c2669abd06e10c8c9 344 Pfam PF01594 AI-2E family transporter 16 327 4.8E-45 T 15-10-2018 IPR002549 Transmembrane protein TqsA-like C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Gene3D G3DSA:1.10.10.1100 416 470 8.2E-11 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Gene3D G3DSA:3.50.50.60 110 244 3.9E-93 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 SUPERFAMILY SSF51905 2 193 1.56E-42 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 SUPERFAMILY SSF51905 147 302 4.53E-30 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 SUPERFAMILY SSF55124 517 635 1.42E-23 T 15-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 556 618 7.5E-14 T 15-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 626 761 6.0E-26 T 15-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 791 0.0 T 15-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Gene3D G3DSA:3.30.413.10 633 761 9.7E-32 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Pfam PF04324 BFD-like [2Fe-2S] binding domain 481 530 3.2E-11 T 15-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Pfam PF04324 BFD-like [2Fe-2S] binding domain 416 465 8.3E-14 T 15-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PIRSF PIRSF037149 1 804 0.0 T 15-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 4.5E-14 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 4.5E-14 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.5E-14 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 4.5E-14 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 SUPERFAMILY SSF56014 627 794 1.96E-49 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Gene3D G3DSA:3.30.390.30 316 398 4.1E-12 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 280 1.0E-57 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00397 Sirohaem Fe-binding site signature 673 691 6.0E-7 T 15-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00397 Sirohaem Fe-binding site signature 630 648 6.0E-7 T 15-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Gene3D G3DSA:3.90.480.20 540 632 3.7E-5 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.7E-24 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.7E-24 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 3.7E-24 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.7E-24 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 3.7E-24 T 15-10-2018 C2I28_13850 a14fb7bf19595e66d5fe93473918e36e 804 Gene3D G3DSA:3.50.50.60 7 280 3.9E-93 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11525 57231ba5947dcad92b607d464519b095 253 Pfam PF12758 Protein of unknown function (DUF3813) 1 66 1.1E-6 T 15-10-2018 IPR024217 Protein of unknown function DUF3813 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 SUPERFAMILY SSF55604 11 86 1.31E-16 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 Pfam PF00367 phosphotransferase system, EIIB 14 40 4.4E-11 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 Pfam PF02378 Phosphotransferase system, EIIC 111 391 5.6E-27 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 Gene3D G3DSA:3.30.1360.60 4 82 2.2E-23 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 544 556 - T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 481 605 2.1E-50 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 8 624 2.0E-193 T 15-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 SUPERFAMILY SSF51261 475 625 1.06E-53 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 Gene3D G3DSA:2.70.70.10 470 625 6.5E-56 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_24690 949f96d24c8dc0e8e53cf31af5b8d8ec 628 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 482 602 1.2E-43 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_18900 5e96fc1102ee91a17af793913977bdb2 246 Gene3D G3DSA:3.90.550.20 7 232 1.5E-35 T 15-10-2018 C2I28_18900 5e96fc1102ee91a17af793913977bdb2 246 SUPERFAMILY SSF53448 5 224 1.14E-67 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18900 5e96fc1102ee91a17af793913977bdb2 246 Pfam PF05704 Capsular polysaccharide synthesis protein 4 112 2.3E-14 T 15-10-2018 IPR008441 Capsular polysaccharide synthesis protein C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 ProSitePatterns PS00438 Catalase proximal active site signature. 65 81 - T 15-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 SUPERFAMILY SSF52317 538 677 4.12E-16 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 Pfam PF06628 Catalase-related immune-responsive 444 507 3.0E-22 T 15-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 359 367 - T 15-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 Gene3D G3DSA:3.40.50.880 538 680 1.7E-36 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 Pfam PF00199 Catalase 29 413 2.6E-182 T 15-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PRINTS PR00067 Catalase signature 145 163 2.2E-71 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PRINTS PR00067 Catalase signature 346 372 2.2E-71 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PRINTS PR00067 Catalase signature 42 65 2.2E-71 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PRINTS PR00067 Catalase signature 126 143 2.2E-71 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PRINTS PR00067 Catalase signature 105 123 2.2E-71 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PRINTS PR00067 Catalase signature 314 341 2.2E-71 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 Gene3D G3DSA:2.40.180.10 1 439 9.5E-214 T 15-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 SUPERFAMILY SSF56634 10 514 9.42E-227 T 15-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 PIRSF PIRSF038927 1 680 0.0 T 15-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 Gene3D G3DSA:1.20.1370.20 440 534 3.8E-32 T 15-10-2018 C2I28_01275 d32cdbb6736a8cb70fe797c464103e85 680 SMART SM01060 29 417 4.5E-281 T 15-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 15-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 Gene3D G3DSA:3.90.180.10 19 348 7.4E-140 T 15-10-2018 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 Pfam PF00107 Zinc-binding dehydrogenase 192 314 1.6E-26 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 Gene3D G3DSA:3.40.50.720 166 320 7.4E-140 T 15-10-2018 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 SMART SM00829 12 348 1.6E-8 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 150 7.3E-28 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 SUPERFAMILY SSF50129 17 178 8.67E-55 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_25285 db9bbf132d1bc113df7ef7d234465e94 353 SUPERFAMILY SSF51735 155 318 3.3E-45 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_13490 ec7a18250932ffb3f77781401b515777 438 PIRSF PIRSF000521 127 432 4.1E-44 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_13490 ec7a18250932ffb3f77781401b515777 438 PIRSF PIRSF000521 25 133 9.5E-10 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_13490 ec7a18250932ffb3f77781401b515777 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_13490 ec7a18250932ffb3f77781401b515777 438 Pfam PF00202 Aminotransferase class-III 23 429 9.0E-137 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_13490 ec7a18250932ffb3f77781401b515777 438 SUPERFAMILY SSF53383 25 432 5.84E-130 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_13490 ec7a18250932ffb3f77781401b515777 438 Gene3D G3DSA:3.90.1150.10 14 425 2.6E-152 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_13490 ec7a18250932ffb3f77781401b515777 438 Gene3D G3DSA:3.40.640.10 62 328 2.6E-152 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_01010 dde1df0c81995c7b6025c20f4b41e243 115 Pfam PF10842 Protein of unknown function (DUF2642) 63 112 8.2E-5 T 15-10-2018 IPR020139 Protein of unknown function DUF2642 C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 Gene3D G3DSA:2.130.10.10 8 185 2.3E-44 T 15-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 190 227 6.2E-12 T 15-10-2018 IPR011964 YVTN beta-propeller repeat C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 24 59 2.3E-8 T 15-10-2018 IPR011964 YVTN beta-propeller repeat C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 150 184 3.2E-11 T 15-10-2018 IPR011964 YVTN beta-propeller repeat C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 233 264 1.1E-7 T 15-10-2018 IPR011964 YVTN beta-propeller repeat C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 63 104 1.6E-13 T 15-10-2018 IPR011964 YVTN beta-propeller repeat C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 107 142 1.0E-10 T 15-10-2018 IPR011964 YVTN beta-propeller repeat C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 SUPERFAMILY SSF50974 23 265 3.4E-48 T 15-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 C2I28_27390 b0a4290fcadfeee022ac1928514c8e9c 273 Gene3D G3DSA:2.130.10.10 186 270 6.9E-18 T 15-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 C2I28_03015 41321763ef8838d30c400d8e54b00c7b 70 SUPERFAMILY SSF51230 3 69 4.45E-19 T 15-10-2018 IPR011053 Single hybrid motif C2I28_03015 41321763ef8838d30c400d8e54b00c7b 70 Gene3D G3DSA:2.40.50.100 3 70 1.0E-20 T 15-10-2018 C2I28_03015 41321763ef8838d30c400d8e54b00c7b 70 Pfam PF00364 Biotin-requiring enzyme 3 69 5.7E-16 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_01485 7c300478d433a8c988482e0bdc1678b0 206 PIRSF PIRSF006324 1 205 4.8E-53 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_01485 7c300478d433a8c988482e0bdc1678b0 206 Pfam PF01810 LysE type translocator 15 203 4.1E-36 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 49.281 T 15-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 Gene3D G3DSA:3.40.50.460 142 251 9.7E-118 T 15-10-2018 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 Gene3D G3DSA:3.40.50.450 3 279 9.7E-118 T 15-10-2018 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 SUPERFAMILY SSF53784 1 315 1.16E-117 T 15-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.3E-90 T 15-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 Pfam PF00365 Phosphofructokinase 3 275 3.1E-114 T 15-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 PIRSF PIRSF000532 1 319 7.5E-125 T 15-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 2.0E-136 T 15-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 C2I28_01535 55246b590a52a5dc73ca676ee47d5fd0 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 15-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 C2I28_01780 3de89db8140b42e27dcd60de5728f924 449 Pfam PF00202 Aminotransferase class-III 17 436 1.5E-103 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01780 3de89db8140b42e27dcd60de5728f924 449 Gene3D G3DSA:3.90.1150.10 17 436 2.2E-145 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_01780 3de89db8140b42e27dcd60de5728f924 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01780 3de89db8140b42e27dcd60de5728f924 449 PIRSF PIRSF000521 14 436 1.8E-38 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01780 3de89db8140b42e27dcd60de5728f924 449 Gene3D G3DSA:3.40.640.10 50 327 2.2E-145 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_01780 3de89db8140b42e27dcd60de5728f924 449 SUPERFAMILY SSF53383 10 437 3.21E-116 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_19695 e648cbaab577f102b8efdc21f2e9197b 246 Gene3D G3DSA:3.60.21.10 1 246 2.0E-63 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_19695 e648cbaab577f102b8efdc21f2e9197b 246 PIRSF PIRSF000883 2 243 1.8E-56 T 15-10-2018 IPR011152 Phosphoesterase MJ0912 C2I28_19695 e648cbaab577f102b8efdc21f2e9197b 246 SUPERFAMILY SSF56300 1 233 1.09E-50 T 15-10-2018 C2I28_19695 e648cbaab577f102b8efdc21f2e9197b 246 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 194 5.2E-24 T 15-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 SUPERFAMILY SSF54980 392 464 3.42E-15 T 15-10-2018 IPR035647 EF-G domain III/V-like C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 PRINTS PR00315 GTP-binding elongation factor signature 15 28 7.5E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 PRINTS PR00315 GTP-binding elongation factor signature 65 73 7.5E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 PRINTS PR00315 GTP-binding elongation factor signature 85 95 7.5E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 PRINTS PR00315 GTP-binding elongation factor signature 101 112 7.5E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 PRINTS PR00315 GTP-binding elongation factor signature 137 146 7.5E-12 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 15-10-2018 IPR031157 Tr-type G domain, conserved site C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 SUPERFAMILY SSF50447 260 386 2.65E-25 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Gene3D G3DSA:3.40.50.300 72 377 6.8E-105 T 15-10-2018 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Pfam PF03144 Elongation factor Tu domain 2 312 377 2.5E-9 T 15-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 148 4.3E-20 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Pfam PF00009 Elongation factor Tu GTP binding domain 13 272 2.7E-49 T 15-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 1 520 1.4E-197 T 15-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 523 48.323 T 15-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Pfam PF16658 Class II release factor RF3, C-terminal domain 386 509 5.0E-40 T 15-10-2018 IPR032090 Peptide chain release factor 3, C-terminal C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Gene3D G3DSA:3.30.70.3280 389 523 3.3E-42 T 15-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 SUPERFAMILY SSF52540 11 273 3.88E-84 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23965 30ee4211071ee784a9b48c42380afdf1 525 Gene3D G3DSA:3.40.50.300 110 273 6.8E-105 T 15-10-2018 C2I28_03630 f0097555d0605f962c0aa9b73f45f47e 318 SUPERFAMILY SSF56281 3 302 5.5E-42 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_03630 f0097555d0605f962c0aa9b73f45f47e 318 Pfam PF00753 Metallo-beta-lactamase superfamily 17 231 2.1E-17 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_03630 f0097555d0605f962c0aa9b73f45f47e 318 Gene3D G3DSA:3.60.15.10 1 259 1.4E-49 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_03630 f0097555d0605f962c0aa9b73f45f47e 318 SMART SM00849 18 231 7.4E-21 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_05145 8e460ab372fbd9e8d46ceec77a25828b 166 PIRSF PIRSF005028 1 163 8.2E-56 T 15-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT C2I28_05145 8e460ab372fbd9e8d46ceec77a25828b 166 SUPERFAMILY SSF116726 79 158 1.83E-15 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_05145 8e460ab372fbd9e8d46ceec77a25828b 166 Gene3D G3DSA:3.30.70.1450 84 162 1.5E-16 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_05145 8e460ab372fbd9e8d46ceec77a25828b 166 Pfam PF02080 TrkA-C domain 90 159 2.0E-12 T 15-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I28_20350 fb2ff844ceb77f191d8649f00a62bb44 264 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 162 172 - T 15-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I28_20350 fb2ff844ceb77f191d8649f00a62bb44 264 Pfam PF01226 Formate/nitrite transporter 10 249 8.5E-78 T 15-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 C2I28_20350 fb2ff844ceb77f191d8649f00a62bb44 264 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 20 252 1.2E-77 T 15-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 C2I28_20350 fb2ff844ceb77f191d8649f00a62bb44 264 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 77 86 - T 15-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I28_20350 fb2ff844ceb77f191d8649f00a62bb44 264 Gene3D G3DSA:1.20.1080.10 4 263 4.0E-85 T 15-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I28_14005 20afdfd246041b428835531bb3de0827 236 Pfam PF00005 ABC transporter 17 158 2.7E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14005 20afdfd246041b428835531bb3de0827 236 Gene3D G3DSA:3.40.50.300 1 235 7.9E-71 T 15-10-2018 C2I28_14005 20afdfd246041b428835531bb3de0827 236 SMART SM00382 26 206 1.7E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14005 20afdfd246041b428835531bb3de0827 236 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_14005 20afdfd246041b428835531bb3de0827 236 SUPERFAMILY SSF52540 1 220 9.95E-64 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23275 f6a2e3f59b034fcdaf174639c2260522 555 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 554 1.7E-209 T 15-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I28_23275 f6a2e3f59b034fcdaf174639c2260522 555 PIRSF PIRSF001294 2 555 1.3E-226 T 15-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I28_23275 f6a2e3f59b034fcdaf174639c2260522 555 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 555 32.165 T 15-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I28_23275 f6a2e3f59b034fcdaf174639c2260522 555 Pfam PF03814 Potassium-transporting ATPase A subunit 10 553 4.3E-226 T 15-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 PIRSF PIRSF005261 1 291 2.9E-81 T 15-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 Gene3D G3DSA:3.55.30.10 2 233 5.0E-94 T 15-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 SUPERFAMILY SSF64397 3 241 1.1E-77 T 15-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 41.677 T 15-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 SUPERFAMILY SSF118352 231 289 1.11E-21 T 15-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 Pfam PF01430 Hsp33 protein 3 280 1.8E-93 T 15-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 C2I28_08470 d3460dba8847b8e4cab79e63853c63c3 292 Gene3D G3DSA:3.90.1280.10 234 292 3.2E-24 T 15-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 C2I28_21060 30637ac97d907b27ea78f2d65875c745 69 Pfam PF10031 Small integral membrane protein (DUF2273) 9 53 3.5E-15 T 15-10-2018 IPR018730 Protein of unknown function DUF2273 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 SUPERFAMILY SSF48498 81 194 1.54E-27 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 Gene3D G3DSA:1.10.357.10 59 198 1.0E-39 T 15-10-2018 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 Gene3D G3DSA:1.10.10.60 10 58 2.9E-21 T 15-10-2018 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.0E-11 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.0E-11 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 Pfam PF08360 QacR-like protein, C-terminal region 68 194 3.7E-24 T 15-10-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 SUPERFAMILY SSF46689 4 76 3.28E-19 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_18610 f739dacb5c441d7edc7fd6119df98f67 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 1.3E-17 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_12060 8b3de6c2827f8c9b5801aafd61518f23 440 Gene3D G3DSA:1.20.1250.20 2 206 3.7E-37 T 15-10-2018 C2I28_12060 8b3de6c2827f8c9b5801aafd61518f23 440 SUPERFAMILY SSF103473 3 428 2.75E-72 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_12060 8b3de6c2827f8c9b5801aafd61518f23 440 Pfam PF07690 Major Facilitator Superfamily 14 389 2.9E-45 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_12060 8b3de6c2827f8c9b5801aafd61518f23 440 Gene3D G3DSA:1.20.1250.20 228 428 1.3E-31 T 15-10-2018 C2I28_12445 08726f614479ab284f2ea0533bf327bc 434 TIGRFAM TIGR00784 citMHS: citrate transporter 1 434 1.6E-201 T 15-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 C2I28_12445 08726f614479ab284f2ea0533bf327bc 434 Pfam PF03600 Citrate transporter 13 380 4.5E-52 T 15-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I28_00450 2e377a0ff023075e7699f36ad546d747 69 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 2.9E-21 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_00450 2e377a0ff023075e7699f36ad546d747 69 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_00450 2e377a0ff023075e7699f36ad546d747 69 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_00450 2e377a0ff023075e7699f36ad546d747 69 Gene3D G3DSA:1.10.8.910 10 68 2.8E-30 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_18500 caf7630e04b6c9c6e7cc7e0acbb0230f 161 Pfam PF14039 YusW-like protein 60 149 8.7E-25 T 15-10-2018 IPR025623 YusW-like protein C2I28_04045 aca7bb90036d11e708faec6c18c30e0c 78 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 2 78 1.0E-29 T 15-10-2018 IPR020254 Protein of unknown function DUF2626 C2I28_04045 aca7bb90036d11e708faec6c18c30e0c 78 Pfam PF11117 Protein of unknown function (DUF2626) 2 74 1.3E-36 T 15-10-2018 IPR020254 Protein of unknown function DUF2626 C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 350 515 1.0E-47 T 15-10-2018 IPR000160 GGDEF domain C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 Pfam PF08448 PAS fold 241 345 2.3E-8 T 15-10-2018 IPR013656 PAS fold-4 C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 Gene3D G3DSA:3.30.450.20 237 345 1.0E-12 T 15-10-2018 C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 239 350 1.3E-5 T 15-10-2018 IPR000014 PAS domain C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 Gene3D G3DSA:3.30.70.270 346 519 3.1E-55 T 15-10-2018 C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 SUPERFAMILY SSF55785 246 351 1.21E-10 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 SUPERFAMILY SSF55073 359 518 1.26E-47 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 Pfam PF16927 N-terminal 7TM region of histidine kinase 12 234 1.2E-43 T 15-10-2018 IPR031621 Histidine kinase, N-terminal 7TM region C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 SMART SM00267 343 516 3.0E-60 T 15-10-2018 IPR000160 GGDEF domain C2I28_24770 53dffb198fdee8794a41005100c5ec3e 526 Pfam PF00990 Diguanylate cyclase, GGDEF domain 354 512 1.3E-46 T 15-10-2018 IPR000160 GGDEF domain C2I28_24570 bdfb4023d391050fd4995aecf3b1e5d2 200 SUPERFAMILY SSF53474 5 197 3.67E-19 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_24570 bdfb4023d391050fd4995aecf3b1e5d2 200 Pfam PF01738 Dienelactone hydrolase family 5 196 1.8E-20 T 15-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 C2I28_24570 bdfb4023d391050fd4995aecf3b1e5d2 200 Gene3D G3DSA:3.40.50.1820 2 197 3.9E-21 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_04235 9043981aaf4b1b4f9ea34670ab00ea54 316 Gene3D G3DSA:3.40.1010.20 104 197 1.6E-96 T 15-10-2018 C2I28_04235 9043981aaf4b1b4f9ea34670ab00ea54 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.539 T 15-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 C2I28_04235 9043981aaf4b1b4f9ea34670ab00ea54 316 Pfam PF02401 LytB protein 4 284 1.5E-80 T 15-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 C2I28_04235 9043981aaf4b1b4f9ea34670ab00ea54 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 9.9E-92 T 15-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 C2I28_04235 9043981aaf4b1b4f9ea34670ab00ea54 316 Gene3D G3DSA:3.40.1010.20 7 284 1.6E-96 T 15-10-2018 C2I28_04235 9043981aaf4b1b4f9ea34670ab00ea54 316 Gene3D G3DSA:3.40.50.11270 12 103 1.6E-96 T 15-10-2018 C2I28_15465 d307cb939cb99b7ce3d2d371f2bbfede 326 Pfam PF01032 FecCD transport family 17 322 1.5E-93 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_15465 d307cb939cb99b7ce3d2d371f2bbfede 326 SUPERFAMILY SSF81345 4 322 4.45E-85 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_15465 d307cb939cb99b7ce3d2d371f2bbfede 326 Gene3D G3DSA:1.10.3470.10 2 326 1.9E-99 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Gene3D G3DSA:1.10.268.10 368 464 1.5E-195 T 15-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 803 2.1E-268 T 15-10-2018 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 806 33.672 T 15-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 470 1.8E-149 T 15-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 525 0.13 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 605 649 7.7E-7 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 709 756 3.0E-4 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 696 3.1E-10 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 599 5.1E-8 T 15-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Gene3D G3DSA:3.30.1360.40 235 331 1.5E-195 T 15-10-2018 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 SMART SM00434 10 463 1.7E-258 T 15-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 8 748 0.0 T 15-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Gene3D G3DSA:2.120.10.90 499 808 1.1E-100 T 15-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 Gene3D G3DSA:3.90.199.10 32 485 1.5E-195 T 15-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 SUPERFAMILY SSF56719 30 485 1.57E-167 T 15-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I28_20840 11ad50afd8e8bd560874c1ec77f4c735 808 SUPERFAMILY SSF101904 499 805 1.03E-91 T 15-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal C2I28_18835 847829e01dbb85245653474f1afc06e5 242 Pfam PF02706 Chain length determinant protein 17 77 1.5E-9 T 15-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Pfam PF00575 S1 RNA binding domain 99 167 2.8E-14 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Pfam PF00575 S1 RNA binding domain 270 342 5.0E-22 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Pfam PF00575 S1 RNA binding domain 13 77 1.6E-14 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Pfam PF00575 S1 RNA binding domain 185 256 1.0E-25 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 151 171 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 208 229 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 286 305 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 325 343 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 81 100 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 16 34 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 105 121 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 PRINTS PR00681 Ribosomal protein S1 signature 122 139 3.3E-53 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SUPERFAMILY SSF50249 87 171 1.72E-16 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SMART SM00316 186 256 1.2E-29 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SMART SM00316 271 342 1.4E-24 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SMART SM00316 14 84 3.4E-16 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SMART SM00316 100 167 1.2E-11 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Gene3D G3DSA:2.40.50.140 3 94 4.7E-17 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SUPERFAMILY SSF50249 8 109 2.14E-19 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SUPERFAMILY SSF50249 185 273 7.75E-28 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 SUPERFAMILY SSF50249 252 348 4.26E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Gene3D G3DSA:2.40.50.140 95 173 4.5E-13 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Gene3D G3DSA:2.40.50.140 183 265 7.4E-30 T 15-10-2018 C2I28_03290 c7746c0bdce25124e90d44cc00069f68 378 Gene3D G3DSA:2.40.50.140 267 351 2.2E-27 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 1 21 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 214 233 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 5.2E-57 T 15-10-2018 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 Pfam PF00375 Sodium:dicarboxylate symporter family 3 397 5.3E-136 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 Gene3D G3DSA:1.10.3860.10 1 410 7.6E-142 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_01785 d1e7900eaadebf84cb8fcfc34e3abcc7 411 SUPERFAMILY SSF118215 3 398 7.06E-124 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_13040 1efd680f80a76e3e1b52b7cd97308f64 449 Gene3D G3DSA:1.20.1740.10 6 443 4.1E-71 T 15-10-2018 C2I28_13040 1efd680f80a76e3e1b52b7cd97308f64 449 Pfam PF00324 Amino acid permease 19 406 3.4E-40 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_13040 1efd680f80a76e3e1b52b7cd97308f64 449 PIRSF PIRSF006060 1 445 8.1E-70 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 SMART SM00345 17 76 2.5E-18 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 Gene3D G3DSA:3.90.1150.10 114 472 9.2E-105 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 Pfam PF00155 Aminotransferase class I and II 118 468 8.7E-34 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 9.5E-7 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 9.5E-7 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 4.4E-18 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 Gene3D G3DSA:1.10.10.10 4 78 4.0E-23 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 Gene3D G3DSA:3.40.640.10 151 371 9.2E-105 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 SUPERFAMILY SSF46785 6 78 1.11E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21640 ad8a50ede4da405c65d5c085e9c683b6 477 SUPERFAMILY SSF53383 110 475 3.86E-97 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 Pfam PF02734 DAK2 domain 399 580 1.4E-49 T 15-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 SUPERFAMILY SSF101473 360 581 4.45E-44 T 15-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 Gene3D G3DSA:3.40.50.10440 13 181 1.1E-67 T 15-10-2018 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 SMART SM01120 398 581 3.8E-59 T 15-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 Gene3D G3DSA:3.30.1180.20 183 328 2.8E-47 T 15-10-2018 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 377 580 3.3E-41 T 15-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 Gene3D G3DSA:1.25.40.340 367 585 7.3E-55 T 15-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 Pfam PF02733 Dak1 domain 17 327 2.9E-126 T 15-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 SUPERFAMILY SSF82549 1 329 3.66E-121 T 15-10-2018 C2I28_16750 f65439290ded98bef9eafac1a723a9ca 587 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 327 3.2E-136 T 15-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 Gene3D G3DSA:2.40.50.100 59 216 5.3E-38 T 15-10-2018 C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 257 7.9E-11 T 15-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 35 376 1.0E-32 T 15-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 Gene3D G3DSA:2.40.30.170 48 303 5.3E-38 T 15-10-2018 C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 Gene3D G3DSA:2.40.420.20 45 360 5.3E-38 T 15-10-2018 C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 Gene3D G3DSA:1.10.287.470 94 181 5.3E-38 T 15-10-2018 C2I28_12275 720d6a01ffd2892c5ba5669c32b3311d 376 SUPERFAMILY SSF111369 69 170 4.18E-5 T 15-10-2018 C2I28_15560 d0ab9198937a0c2c7120b5741525ac6b 407 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_15560 d0ab9198937a0c2c7120b5741525ac6b 407 Pfam PF07690 Major Facilitator Superfamily 13 274 5.3E-29 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_15560 d0ab9198937a0c2c7120b5741525ac6b 407 Gene3D G3DSA:1.20.1250.20 213 394 3.8E-17 T 15-10-2018 C2I28_15560 d0ab9198937a0c2c7120b5741525ac6b 407 SUPERFAMILY SSF103473 10 393 9.16E-51 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15560 d0ab9198937a0c2c7120b5741525ac6b 407 Gene3D G3DSA:1.20.1250.20 4 193 5.0E-23 T 15-10-2018 C2I28_04965 276508ca0529bc6485c5801e40f350ec 257 Gene3D G3DSA:3.40.50.10090 155 255 8.3E-22 T 15-10-2018 C2I28_04965 276508ca0529bc6485c5801e40f350ec 257 SUPERFAMILY SSF69618 10 256 2.22E-63 T 15-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04965 276508ca0529bc6485c5801e40f350ec 257 Pfam PF02602 Uroporphyrinogen-III synthase HemD 23 249 7.2E-58 T 15-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_04965 276508ca0529bc6485c5801e40f350ec 257 Gene3D G3DSA:3.40.50.10090 9 136 1.5E-29 T 15-10-2018 C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 Pfam PF00589 Phage integrase family 113 286 5.3E-47 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 90 1.5E-19 T 15-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 Gene3D G3DSA:1.10.443.10 112 294 8.3E-58 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 SUPERFAMILY SSF56349 4 294 1.91E-55 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 Gene3D G3DSA:1.10.150.130 5 99 4.3E-24 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 300 54.741 T 15-10-2018 IPR023009 Tyrosine recombinase XerC/XerD C2I28_02565 8a4960ec6d25649350ee37b629d6c15f 300 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 10 300 1.9E-106 T 15-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 C2I28_21770 e4eba9d973ab4ae11f88135a48819dd9 318 SUPERFAMILY SSF52151 4 304 1.15E-23 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_21770 e4eba9d973ab4ae11f88135a48819dd9 318 Pfam PF01734 Patatin-like phospholipase 8 172 1.5E-12 T 15-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I28_21770 e4eba9d973ab4ae11f88135a48819dd9 318 Gene3D G3DSA:3.40.1090.10 2 302 5.2E-27 T 15-10-2018 C2I28_13895 2f8eef582a6bde4dbd6435c43efd6e73 460 PIRSF PIRSF006603 2 459 1.3E-137 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_13895 2f8eef582a6bde4dbd6435c43efd6e73 460 Pfam PF01554 MatE 254 415 9.1E-33 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_13895 2f8eef582a6bde4dbd6435c43efd6e73 460 Pfam PF01554 MatE 27 187 1.7E-37 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_13895 2f8eef582a6bde4dbd6435c43efd6e73 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 428 4.4E-97 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 SMART SM00354 1 71 4.6E-30 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 SUPERFAMILY SSF53822 58 299 9.06E-58 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.1E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.1E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 Gene3D G3DSA:3.40.50.2300 60 298 4.9E-61 T 15-10-2018 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 15-10-2018 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 Pfam PF13377 Periplasmic binding protein-like domain 168 299 2.5E-24 T 15-10-2018 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 SUPERFAMILY SSF47413 1 60 5.79E-17 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 5.1E-19 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 Gene3D G3DSA:1.10.260.40 3 59 1.5E-20 T 15-10-2018 C2I28_19135 cc039d0d8e8d64d2b1e95afc0a21c125 319 Gene3D G3DSA:3.40.50.2300 158 285 4.9E-61 T 15-10-2018 C2I28_26515 3b78910d33a57c4bec1e9681d29dc977 100 Gene3D G3DSA:1.20.1290.10 1 100 4.1E-20 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_26515 3b78910d33a57c4bec1e9681d29dc977 100 Pfam PF02627 Carboxymuconolactone decarboxylase family 9 88 2.6E-11 T 15-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_26515 3b78910d33a57c4bec1e9681d29dc977 100 SUPERFAMILY SSF69118 5 96 1.15E-18 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_10160 d6813819f34c62f1dacddfde010187a0 144 Gene3D G3DSA:3.30.1490.190 87 144 2.9E-23 T 15-10-2018 C2I28_10160 d6813819f34c62f1dacddfde010187a0 144 Pfam PF01475 Ferric uptake regulator family 15 132 1.8E-39 T 15-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 C2I28_10160 d6813819f34c62f1dacddfde010187a0 144 SUPERFAMILY SSF46785 7 137 3.2E-41 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_10160 d6813819f34c62f1dacddfde010187a0 144 Gene3D G3DSA:1.10.10.10 1 86 8.2E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06625 c9f242648644e6ba497538ece8a77f84 349 Pfam PF01032 FecCD transport family 31 345 5.8E-89 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_06625 c9f242648644e6ba497538ece8a77f84 349 SUPERFAMILY SSF81345 14 345 1.83E-78 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_06625 c9f242648644e6ba497538ece8a77f84 349 Gene3D G3DSA:1.10.3470.10 18 349 1.4E-92 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 SMART SM00421 149 206 3.2E-27 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.5E-22 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 Gene3D G3DSA:3.40.50.12740 4 212 8.7E-67 T 15-10-2018 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 SMART SM00448 4 120 2.2E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 SUPERFAMILY SSF52172 3 121 1.99E-32 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.4E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.4E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.4E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 Pfam PF00072 Response regulator receiver domain 6 111 4.9E-28 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_24195 ed2aad58d09a35842db0cfbf20648d96 213 SUPERFAMILY SSF46894 142 212 5.1E-23 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_12230 2c395de7b4972412ecdec24e241ee1d6 169 Pfam PF03061 Thioesterase superfamily 25 99 2.3E-15 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_12230 2c395de7b4972412ecdec24e241ee1d6 169 SUPERFAMILY SSF54637 2 154 1.3E-46 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_12230 2c395de7b4972412ecdec24e241ee1d6 169 Gene3D G3DSA:3.10.129.10 1 165 2.1E-57 T 15-10-2018 C2I28_13600 6618e9cc3e652eadbea549e45e4fa7a2 301 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 1 257 6.0E-13 T 15-10-2018 C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 SMART SM00642 13 415 8.7E-159 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 Pfam PF00128 Alpha amylase, catalytic domain 28 373 5.4E-118 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 549 2.5E-8 T 15-10-2018 IPR032091 Maltogenic Amylase, C-terminal C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 Gene3D G3DSA:2.60.40.1180 477 555 3.4E-22 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 Gene3D G3DSA:3.90.400.10 102 173 3.4E-198 T 15-10-2018 C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 SUPERFAMILY SSF51445 3 473 2.95E-158 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 Gene3D G3DSA:3.20.20.80 5 468 3.4E-198 T 15-10-2018 C2I28_15220 12c44f6ef324580a94c64f8dca346546 555 SUPERFAMILY SSF51011 476 554 1.34E-17 T 15-10-2018 C2I28_21195 4be056d23fdc1e41755582adc4270232 367 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 11 362 29.604 T 15-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 C2I28_21195 4be056d23fdc1e41755582adc4270232 367 SUPERFAMILY SSF111342 5 288 6.67E-86 T 15-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 C2I28_21195 4be056d23fdc1e41755582adc4270232 367 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 18 360 3.7E-67 T 15-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 C2I28_21195 4be056d23fdc1e41755582adc4270232 367 PIRSF PIRSF026782 7 367 1.1E-128 T 15-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 C2I28_21195 4be056d23fdc1e41755582adc4270232 367 Pfam PF01888 CbiD 11 271 3.4E-96 T 15-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 C2I28_21195 4be056d23fdc1e41755582adc4270232 367 Gene3D G3DSA:3.30.2110.10 13 185 1.0E-49 T 15-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 C2I28_18060 4b742a0bc3ad0996906b4e5d967a2685 470 PIRSF PIRSF006060 1 468 1.6E-84 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_18060 4b742a0bc3ad0996906b4e5d967a2685 470 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_18060 4b742a0bc3ad0996906b4e5d967a2685 470 Pfam PF00324 Amino acid permease 19 457 1.7E-125 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_18060 4b742a0bc3ad0996906b4e5d967a2685 470 Gene3D G3DSA:1.20.1740.10 8 466 2.4E-67 T 15-10-2018 C2I28_13225 eb39fa200887aba441b4454579df373c 362 Gene3D G3DSA:2.40.100.10 243 361 1.4E-41 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_13225 eb39fa200887aba441b4454579df373c 362 SUPERFAMILY SSF51445 1 240 1.92E-90 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_13225 eb39fa200887aba441b4454579df373c 362 SUPERFAMILY SSF50891 246 360 2.73E-39 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_13225 eb39fa200887aba441b4454579df373c 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 359 6.6E-142 T 15-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic C2I28_13225 eb39fa200887aba441b4454579df373c 362 Gene3D G3DSA:3.20.20.70 1 241 2.3E-88 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 Pfam PF00271 Helicase conserved C-terminal domain 360 466 2.9E-19 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 Gene3D G3DSA:3.40.50.300 328 549 2.3E-45 T 15-10-2018 C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 SUPERFAMILY SSF52540 25 259 6.99E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 SMART SM00490 386 466 6.6E-19 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 Pfam PF00176 SNF2 family N-terminal domain 79 334 1.7E-35 T 15-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 SMART SM00487 56 232 6.1E-31 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 SUPERFAMILY SSF52540 168 519 3.41E-55 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03990 0f2550b6b12f138e2dd29ab9d363c087 557 Gene3D G3DSA:3.40.50.10810 58 281 9.7E-60 T 15-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily C2I28_24130 da11821b4f79fddf4af33f9c63468bc3 146 Gene3D G3DSA:1.10.10.2520 8 96 1.9E-11 T 15-10-2018 C2I28_24130 da11821b4f79fddf4af33f9c63468bc3 146 Pfam PF07486 Cell Wall Hydrolase 24 133 7.9E-17 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1064 13.483 T 15-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SUPERFAMILY SSF48108 395 546 1.57E-48 T 15-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.1E-64 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SUPERFAMILY SSF56059 666 927 4.6E-101 T 15-10-2018 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SMART SM00851 949 1036 7.5E-25 T 15-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SMART SM01096 420 540 1.1E-62 T 15-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SMART SM01209 674 836 0.0061 T 15-10-2018 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SUPERFAMILY SSF52335 929 1051 8.63E-31 T 15-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SUPERFAMILY SSF52440 1 127 2.59E-50 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Gene3D G3DSA:3.40.50.20 1 116 9.8E-49 T 15-10-2018 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Gene3D G3DSA:3.30.470.20 659 929 3.6E-106 T 15-10-2018 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 5.5E-39 T 15-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Gene3D G3DSA:3.40.50.1380 931 1066 7.1E-36 T 15-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Gene3D G3DSA:1.10.1030.10 402 546 2.3E-43 T 15-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 15-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SUPERFAMILY SSF56059 128 399 2.12E-108 T 15-10-2018 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Pfam PF02142 MGS-like domain 951 1036 1.2E-17 T 15-10-2018 IPR011607 Methylglyoxal synthase-like domain C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.181 T 15-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 SUPERFAMILY SSF52440 549 668 3.74E-48 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Gene3D G3DSA:3.40.50.20 547 655 1.8E-46 T 15-10-2018 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 1.7E-80 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 8.0E-39 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_02835 1cf97ceb0b1735f23853bb68f8bb1f98 1070 Gene3D G3DSA:3.30.470.20 120 401 9.2E-125 T 15-10-2018 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 SUPERFAMILY SSF47384 247 329 4.9E-16 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 Gene3D G3DSA:3.30.565.10 336 489 2.4E-34 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 487 1.4E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 SMART SM00388 264 331 4.4E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 SMART SM00387 377 488 4.8E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 442 4.2E-6 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 4.2E-6 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 Gene3D G3DSA:1.10.287.130 202 327 3.7E-22 T 15-10-2018 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 SUPERFAMILY SSF55874 335 487 5.5E-35 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 Pfam PF00512 His Kinase A (phospho-acceptor) domain 264 328 1.3E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 SMART SM00304 204 256 4.9E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_20485 a226a2ff2e528eed9b09910d6adb3226 500 SUPERFAMILY SSF158472 204 254 4.58E-7 T 15-10-2018 C2I28_22315 ca561569f0bfe9c460df2b3acd74aa13 677 Pfam PF00999 Sodium/hydrogen exchanger family 6 412 8.5E-64 T 15-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I28_22315 ca561569f0bfe9c460df2b3acd74aa13 677 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 8 514 5.3E-104 T 15-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 C2I28_07650 57f4098803902c3ea8fce1e828e4ed5a 274 Gene3D G3DSA:3.40.1190.20 1 271 3.6E-90 T 15-10-2018 IPR029056 Ribokinase-like C2I28_07650 57f4098803902c3ea8fce1e828e4ed5a 274 SUPERFAMILY SSF53613 3 267 4.83E-74 T 15-10-2018 IPR029056 Ribokinase-like C2I28_07650 57f4098803902c3ea8fce1e828e4ed5a 274 Pfam PF08543 Phosphomethylpyrimidine kinase 13 261 2.6E-90 T 15-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 C2I28_07650 57f4098803902c3ea8fce1e828e4ed5a 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 2.2E-86 T 15-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_19180 069fc42b45b4954ab41514ed87b31bbb 373 Pfam PF03845 Spore germination protein 6 321 1.7E-46 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_19180 069fc42b45b4954ab41514ed87b31bbb 373 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 360 3.9E-58 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_20055 2faa6c59121a2b0dbbfb2cd9ce972f2d 153 Pfam PF12802 MarR family 37 85 6.4E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_20055 2faa6c59121a2b0dbbfb2cd9ce972f2d 153 Gene3D G3DSA:1.10.10.10 4 146 2.2E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20055 2faa6c59121a2b0dbbfb2cd9ce972f2d 153 SUPERFAMILY SSF46785 32 143 3.46E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20055 2faa6c59121a2b0dbbfb2cd9ce972f2d 153 SMART SM00347 29 131 2.9E-16 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Gene3D G3DSA:2.30.130.40 1 114 7.8E-32 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Gene3D G3DSA:3.40.50.300 311 489 1.9E-68 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 488 7.6E-23 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 SUPERFAMILY SSF52540 310 586 1.6E-55 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Gene3D G3DSA:1.10.8.60 490 582 1.3E-33 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 199 6.2E-43 T 15-10-2018 IPR003111 Lon, substrate-binding domain C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 SUPERFAMILY SSF88697 8 199 5.72E-46 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 15-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Gene3D G3DSA:1.20.58.1480 119 243 2.5E-42 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 PIRSF PIRSF001174 1 773 0.0 T 15-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 SUPERFAMILY SSF54211 593 768 3.68E-56 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Hamap MF_01973 Lon protease [lon]. 9 770 72.343 T 15-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 SMART SM00464 8 200 1.7E-70 T 15-10-2018 IPR003111 Lon, substrate-binding domain C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 0.0 T 15-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 SMART SM00382 346 491 1.9E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Gene3D G3DSA:3.30.230.10 591 774 3.0E-85 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 8.1E-100 T 15-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 1.8E-52 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 1.8E-52 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 1.8E-52 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 1.8E-52 T 15-10-2018 C2I28_04995 b04378f423f09c02c4ffe95a757a9218 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 1.8E-52 T 15-10-2018 C2I28_16090 6ac9bd06e0704889e023db49be7d69c3 175 Gene3D G3DSA:3.40.630.30 4 174 8.6E-46 T 15-10-2018 C2I28_16090 6ac9bd06e0704889e023db49be7d69c3 175 Pfam PF00583 Acetyltransferase (GNAT) family 35 149 1.3E-16 T 15-10-2018 IPR000182 GNAT domain C2I28_16090 6ac9bd06e0704889e023db49be7d69c3 175 SUPERFAMILY SSF55729 4 166 2.09E-31 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 37 52 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 SUPERFAMILY SSF118215 8 403 1.03E-125 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 Pfam PF00375 Sodium:dicarboxylate symporter family 8 402 1.2E-124 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 Gene3D G3DSA:1.10.3860.10 1 419 4.5E-134 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 1.7E-36 T 15-10-2018 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 1.7E-36 T 15-10-2018 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 1.7E-36 T 15-10-2018 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 356 376 1.7E-36 T 15-10-2018 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 1.7E-36 T 15-10-2018 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 1.7E-36 T 15-10-2018 C2I28_13420 37905baec94fbabbf1c3d082ac902903 423 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 1.7E-36 T 15-10-2018 C2I28_14535 8c1da232059768f8b46283ebab6b07d1 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 5.4E-60 T 15-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14535 8c1da232059768f8b46283ebab6b07d1 156 SUPERFAMILY SSF52121 4 154 1.07E-64 T 15-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14535 8c1da232059768f8b46283ebab6b07d1 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 2.5E-62 T 15-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14535 8c1da232059768f8b46283ebab6b07d1 156 Gene3D G3DSA:3.40.50.960 2 155 1.8E-66 T 15-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14535 8c1da232059768f8b46283ebab6b07d1 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 32.053 T 15-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_07050 472612a3e6174ca19e91083633c31a8f 586 Gene3D G3DSA:2.60.40.380 60 168 2.9E-42 T 15-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 C2I28_07050 472612a3e6174ca19e91083633c31a8f 586 Pfam PF09423 PhoD-like phosphatase 178 515 1.6E-117 T 15-10-2018 IPR018946 Alkaline phosphatase D-related C2I28_07050 472612a3e6174ca19e91083633c31a8f 586 Gene3D G3DSA:3.60.21.70 169 586 9.1E-173 T 15-10-2018 IPR038607 PhoD-like superfamily C2I28_07050 472612a3e6174ca19e91083633c31a8f 586 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 70 165 2.1E-32 T 15-10-2018 IPR032093 Phospholipase D, N-terminal C2I28_07050 472612a3e6174ca19e91083633c31a8f 586 SUPERFAMILY SSF56300 175 517 1.1E-41 T 15-10-2018 C2I28_25260 0c480907f2889d897b078b1e67d2c9b1 109 Gene3D G3DSA:1.20.1270.360 2 109 4.2E-33 T 15-10-2018 C2I28_25260 0c480907f2889d897b078b1e67d2c9b1 109 Pfam PF03860 Domain of Unknown Function (DUF326) 87 106 2.9E-7 T 15-10-2018 IPR005560 Protein of unknown function DUF326 C2I28_12955 627c13c730681129a8594e80cf4df096 238 SMART SM00866 90 229 2.7E-27 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_12955 627c13c730681129a8594e80cf4df096 238 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 236 4.1E-97 T 15-10-2018 IPR012770 Trehalose operon transcriptional repressor C2I28_12955 627c13c730681129a8594e80cf4df096 238 SUPERFAMILY SSF46785 4 72 5.09E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12955 627c13c730681129a8594e80cf4df096 238 SMART SM00345 9 68 1.5E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12955 627c13c730681129a8594e80cf4df096 238 SUPERFAMILY SSF64288 74 234 6.28E-43 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_12955 627c13c730681129a8594e80cf4df096 238 Pfam PF07702 UTRA domain 91 229 3.3E-33 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_12955 627c13c730681129a8594e80cf4df096 238 Gene3D G3DSA:1.10.10.10 5 71 5.9E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12955 627c13c730681129a8594e80cf4df096 238 Gene3D G3DSA:3.40.1410.10 88 228 9.1E-33 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_12955 627c13c730681129a8594e80cf4df096 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 1.0E-18 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12955 627c13c730681129a8594e80cf4df096 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.0E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12955 627c13c730681129a8594e80cf4df096 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.0E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_04210 f6593769d14337fdae3468beb0e5a96c 259 Pfam PF00005 ABC transporter 22 170 9.7E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_04210 f6593769d14337fdae3468beb0e5a96c 259 SMART SM00382 31 220 2.7E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04210 f6593769d14337fdae3468beb0e5a96c 259 SUPERFAMILY SSF52540 4 231 2.87E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04210 f6593769d14337fdae3468beb0e5a96c 259 Gene3D G3DSA:3.40.50.300 1 247 1.2E-67 T 15-10-2018 C2I28_04210 f6593769d14337fdae3468beb0e5a96c 259 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 Pfam PF04542 Sigma-70 region 2 24 89 6.8E-23 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 1.3E-99 T 15-10-2018 IPR014294 RNA polymerase sigma-W, bacillaceae C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 Pfam PF08281 Sigma-70, region 4 130 180 3.0E-16 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 Gene3D G3DSA:1.10.1740.10 5 124 1.7E-32 T 15-10-2018 C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 184 3.1E-36 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 SUPERFAMILY SSF88946 8 98 8.79E-30 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 Gene3D G3DSA:1.10.10.10 125 187 1.3E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_08970 193abfe532162ab58fb3ad8bfd528324 187 SUPERFAMILY SSF88659 117 184 7.29E-18 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_06535 ea1a964624703b69271bc207e953ed8d 261 SUPERFAMILY SSF52540 6 233 2.86E-43 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06535 ea1a964624703b69271bc207e953ed8d 261 SMART SM00382 30 225 3.0E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_06535 ea1a964624703b69271bc207e953ed8d 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 1.3E-113 T 15-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 C2I28_06535 ea1a964624703b69271bc207e953ed8d 261 Pfam PF00005 ABC transporter 21 173 2.2E-22 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_06535 ea1a964624703b69271bc207e953ed8d 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_06535 ea1a964624703b69271bc207e953ed8d 261 Gene3D G3DSA:3.40.50.300 5 250 3.4E-56 T 15-10-2018 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 SMART SM01003 4 136 3.7E-78 T 15-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 Gene3D G3DSA:3.40.50.720 3 352 7.1E-140 T 15-10-2018 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 SUPERFAMILY SSF52283 2 360 6.29E-68 T 15-10-2018 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 352 6.2E-84 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 SUPERFAMILY SSF51735 136 303 1.56E-46 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 Gene3D G3DSA:3.40.50.720 129 305 7.1E-140 T 15-10-2018 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 15-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 370 4.3E-180 T 15-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 PIRSF PIRSF000183 1 371 7.6E-192 T 15-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 8.8E-47 T 15-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 SMART SM01002 148 297 7.2E-88 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_05490 3f03bf6a2afbc4ae11f94731548bca2c 373 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 15-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 4.2E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.2E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 4.2E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 4.2E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.2E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 4.2E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 SUPERFAMILY SSF51735 6 257 2.83E-66 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 Gene3D G3DSA:3.40.50.720 1 258 9.6E-69 T 15-10-2018 C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 6.5E-44 T 15-10-2018 C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 2.8E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.8E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16320 ebe7b933f8f22f785e5f0066ce55dae1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 2.8E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25770 1b09e9ba6b2325cd5842e2ee58b13be2 282 SUPERFAMILY SSF52266 2 271 5.49E-77 T 15-10-2018 C2I28_25770 1b09e9ba6b2325cd5842e2ee58b13be2 282 Gene3D G3DSA:1.10.1200.110 248 281 2.3E-5 T 15-10-2018 C2I28_25770 1b09e9ba6b2325cd5842e2ee58b13be2 282 Gene3D G3DSA:3.40.50.1110 1 247 1.2E-84 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_25770 1b09e9ba6b2325cd5842e2ee58b13be2 282 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 4 224 3.6E-54 T 15-10-2018 IPR005181 Sialate O-acetylesterase domain C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 Pfam PF12802 MarR family 35 94 4.4E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 SUPERFAMILY SSF46785 4 144 3.72E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 SMART SM00347 28 130 4.0E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 3.1E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 3.1E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 3.1E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 3.1E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 103 - T 15-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I28_16645 1dd38f45a93ba03c068c02a829ecf8be 189 Gene3D G3DSA:1.10.10.10 2 185 2.9E-46 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25185 2cfb332a41419078a71a14da576de224 485 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 208 218 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_25185 2cfb332a41419078a71a14da576de224 485 SUPERFAMILY SSF52743 154 482 2.23E-70 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_25185 2cfb332a41419078a71a14da576de224 485 Gene3D G3DSA:3.40.50.200 113 484 5.5E-83 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_25185 2cfb332a41419078a71a14da576de224 485 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 15-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I28_25185 2cfb332a41419078a71a14da576de224 485 PRINTS PR00723 Subtilisin serine protease family (S8) signature 421 437 1.8E-17 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_25185 2cfb332a41419078a71a14da576de224 485 PRINTS PR00723 Subtilisin serine protease family (S8) signature 204 217 1.8E-17 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_25185 2cfb332a41419078a71a14da576de224 485 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 1.8E-17 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_25185 2cfb332a41419078a71a14da576de224 485 Pfam PF00082 Subtilase family 159 472 2.6E-48 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_25185 2cfb332a41419078a71a14da576de224 485 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 422 432 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_13160 3122900fd0d573c0dd23008edb4f5d0c 149 Pfam PF12638 Staygreen protein 4 146 2.6E-43 T 15-10-2018 IPR024438 Staygreen protein C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 SUPERFAMILY SSF55874 295 459 2.1E-43 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 Gene3D G3DSA:3.30.565.10 307 460 7.4E-46 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 SMART SM00304 186 238 5.4E-12 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 Gene3D G3DSA:1.10.8.500 185 235 3.2E-12 T 15-10-2018 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 5.2E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 5.2E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 5.2E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 5.2E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 SUPERFAMILY SSF158472 186 236 1.7E-11 T 15-10-2018 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 SMART SM00388 239 305 5.9E-20 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 SUPERFAMILY SSF47384 222 304 1.96E-18 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 Pfam PF00672 HAMP domain 186 234 8.4E-10 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 304 6.0E-16 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 Gene3D G3DSA:1.10.287.130 236 306 2.8E-20 T 15-10-2018 C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 459 1.0E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_24300 0be497758f5d4a36b3a41492628e91c0 460 SMART SM00387 349 460 2.8E-37 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_00985 8a70d8e389626201d7238793534b7fd0 131 Pfam PF07681 DoxX 8 86 3.5E-20 T 15-10-2018 IPR032808 DoxX family C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 Gene3D G3DSA:3.40.50.1000 6 185 4.1E-51 T 15-10-2018 IPR023214 HAD superfamily C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 97 174 4.1E-10 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 5.1E-8 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 5.1E-8 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 5.1E-8 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 5.1E-8 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 SUPERFAMILY SSF56784 1 211 1.23E-58 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 Gene3D G3DSA:1.10.150.240 18 80 4.1E-51 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 6.3E-55 T 15-10-2018 C2I28_06945 727f900ca36ea068bea0b3a96623b8c1 215 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 1 214 44.298 T 15-10-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_09735 419d04deae42188659854e22a5fc58af 162 Pfam PF12867 DinB superfamily 5 153 1.6E-21 T 15-10-2018 IPR024775 DinB-like domain C2I28_09735 419d04deae42188659854e22a5fc58af 162 Gene3D G3DSA:1.20.120.450 1 159 9.6E-44 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_09735 419d04deae42188659854e22a5fc58af 162 SUPERFAMILY SSF109854 4 161 7.02E-28 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16535 28b9b8e2ee48e0f1c1eb8e4379ba0320 112 Gene3D G3DSA:1.10.3730.20 2 108 7.2E-23 T 15-10-2018 C2I28_16535 28b9b8e2ee48e0f1c1eb8e4379ba0320 112 SUPERFAMILY SSF103481 5 105 1.83E-14 T 15-10-2018 C2I28_16535 28b9b8e2ee48e0f1c1eb8e4379ba0320 112 Pfam PF00893 Small Multidrug Resistance protein 3 93 1.8E-16 T 15-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 15-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 SUPERFAMILY SSF53901 273 394 8.64E-41 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 Pfam PF02803 Thiolase, C-terminal domain 273 394 4.7E-47 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 Pfam PF00108 Thiolase, N-terminal domain 6 264 5.6E-112 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 15-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 Gene3D G3DSA:3.40.47.10 128 392 2.8E-159 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 SUPERFAMILY SSF53901 5 272 1.55E-92 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 6.5E-151 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 PIRSF PIRSF000429 1 395 4.0E-131 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 Gene3D G3DSA:3.40.47.10 8 278 2.8E-159 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_03600 2183375064deebdd79cdf2e6e17b0ccf 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 15-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 C2I28_05820 76657fc8ba2b068381a3260d48616921 320 SMART SM00729 32 259 3.3E-43 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_05820 76657fc8ba2b068381a3260d48616921 320 Gene3D G3DSA:3.80.30.20 50 246 2.8E-15 T 15-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I28_05820 76657fc8ba2b068381a3260d48616921 320 SUPERFAMILY SSF102114 8 314 5.1E-55 T 15-10-2018 C2I28_05820 76657fc8ba2b068381a3260d48616921 320 Pfam PF16199 Radical_SAM C-terminal domain 220 303 6.8E-24 T 15-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 C2I28_05820 76657fc8ba2b068381a3260d48616921 320 Pfam PF04055 Radical SAM superfamily 52 214 4.1E-15 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_05820 76657fc8ba2b068381a3260d48616921 320 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 314 4.1E-134 T 15-10-2018 IPR005911 Protein YhcC-like GO:0051536 C2I28_09350 d6a0a9128b18e139aa514a94ae006fd2 316 PIRSF PIRSF002849 2 315 4.2E-131 T 15-10-2018 C2I28_09350 d6a0a9128b18e139aa514a94ae006fd2 316 Gene3D G3DSA:1.10.8.300 207 309 8.5E-32 T 15-10-2018 C2I28_09350 d6a0a9128b18e139aa514a94ae006fd2 316 SUPERFAMILY SSF52540 11 291 1.56E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09350 d6a0a9128b18e139aa514a94ae006fd2 316 Gene3D G3DSA:3.40.50.300 2 206 1.4E-47 T 15-10-2018 C2I28_09350 d6a0a9128b18e139aa514a94ae006fd2 316 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 3.0E-63 T 15-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 C2I28_25965 ce076e741126fc3f76cccda9ddffd6d4 293 Gene3D G3DSA:1.20.1560.10 1 196 8.4E-9 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_25965 ce076e741126fc3f76cccda9ddffd6d4 293 Pfam PF13748 ABC transporter transmembrane region 15 251 4.2E-53 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_25965 ce076e741126fc3f76cccda9ddffd6d4 293 SUPERFAMILY SSF90123 15 289 2.09E-18 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_02040 08d0100707fd9796d03a10de34943128 325 Gene3D G3DSA:3.90.550.10 1 201 2.1E-36 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_02040 08d0100707fd9796d03a10de34943128 325 Pfam PF00535 Glycosyl transferase family 2 6 166 1.5E-34 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_02040 08d0100707fd9796d03a10de34943128 325 SUPERFAMILY SSF53448 3 219 4.13E-37 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_09500 c3865c69b5851f48752b721c92c93131 460 Gene3D G3DSA:3.40.50.800 365 458 3.8E-32 T 15-10-2018 IPR036621 Anticodon-binding domain superfamily C2I28_09500 c3865c69b5851f48752b721c92c93131 460 Pfam PF03129 Anticodon binding domain 369 456 1.0E-22 T 15-10-2018 IPR004154 Anticodon-binding C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 168 185 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 324 336 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 227 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 147 159 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 200 217 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 1.1E-53 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 SUPERFAMILY SSF55681 4 372 1.74E-126 T 15-10-2018 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 243 6.9E-94 T 15-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 SUPERFAMILY SSF52954 356 456 1.66E-32 T 15-10-2018 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 340 2.2E-11 T 15-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_09500 c3865c69b5851f48752b721c92c93131 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 459 52.086 T 15-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 C2I28_11965 1085a180966f7db32e95753f67659c7a 203 Gene3D G3DSA:2.60.120.200 17 203 1.8E-60 T 15-10-2018 C2I28_11965 1085a180966f7db32e95753f67659c7a 203 PIRSF PIRSF022704 12 203 3.9E-62 T 15-10-2018 IPR015987 Uncharacterised conserved protein UCP022704 C2I28_11965 1085a180966f7db32e95753f67659c7a 203 SUPERFAMILY SSF49899 7 202 1.38E-36 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_11965 1085a180966f7db32e95753f67659c7a 203 Pfam PF07081 Protein of unknown function (DUF1349) 22 202 4.5E-63 T 15-10-2018 IPR009784 Protein of unknown function DUF1349 C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 Pfam PF00582 Universal stress protein family 6 147 3.6E-34 T 15-10-2018 IPR006016 UspA C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 PIRSF PIRSF006276 2 150 4.5E-23 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 Gene3D G3DSA:3.40.50.620 8 147 2.2E-40 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 PRINTS PR01438 Universal stress protein signature 125 147 3.3E-18 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 PRINTS PR01438 Universal stress protein signature 107 119 3.3E-18 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 PRINTS PR01438 Universal stress protein signature 6 24 3.3E-18 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17320 5fc561b04948ce33712eb217ea6c8287 165 SUPERFAMILY SSF52402 6 149 3.85E-35 T 15-10-2018 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 SUPERFAMILY SSF52518 358 561 4.91E-61 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 Gene3D G3DSA:3.40.50.1220 183 335 2.2E-46 T 15-10-2018 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 SUPERFAMILY SSF52518 1 172 3.68E-46 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 Gene3D G3DSA:3.40.50.970 348 567 3.6E-58 T 15-10-2018 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 Gene3D G3DSA:3.40.50.970 1 182 1.2E-59 T 15-10-2018 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 SUPERFAMILY SSF52467 188 349 5.4E-43 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 2.2E-40 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 15-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 321 2.9E-34 T 15-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 C2I28_13805 8a99b07eb377aaaa0520641593f59b1a 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 6.1E-46 T 15-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 C2I28_02140 c508530c8dbe78f5e2c41bdcbef43777 305 Gene3D G3DSA:3.20.20.140 1 303 1.3E-100 T 15-10-2018 C2I28_02140 c508530c8dbe78f5e2c41bdcbef43777 305 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 300 1.7E-91 T 15-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 C2I28_02140 c508530c8dbe78f5e2c41bdcbef43777 305 SUPERFAMILY SSF51556 2 300 1.68E-71 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_13200 d2f532ce5fe1d629c4257fcf9588494d 433 Pfam PF02378 Phosphotransferase system, EIIC 29 344 8.0E-60 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_13200 d2f532ce5fe1d629c4257fcf9588494d 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 418 1.4E-124 T 15-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I28_13200 d2f532ce5fe1d629c4257fcf9588494d 433 PIRSF PIRSF006351 1 426 4.8E-151 T 15-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I28_20695 434c10062ad008ebbae620bcd7fe5458 195 Pfam PF01553 Acyltransferase 20 142 1.9E-22 T 15-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I28_20695 434c10062ad008ebbae620bcd7fe5458 195 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 20 141 6.8E-33 T 15-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 C2I28_20695 434c10062ad008ebbae620bcd7fe5458 195 SMART SM00563 33 144 2.3E-26 T 15-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I28_20695 434c10062ad008ebbae620bcd7fe5458 195 SUPERFAMILY SSF69593 18 187 1.02E-36 T 15-10-2018 C2I28_08750 0a4f01868f9dadf10dd3fa6e665930c1 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.615 T 15-10-2018 IPR023053 Ribosomal protein S14, type Z C2I28_08750 0a4f01868f9dadf10dd3fa6e665930c1 61 Gene3D G3DSA:4.10.830.10 1 61 5.7E-30 T 15-10-2018 C2I28_08750 0a4f01868f9dadf10dd3fa6e665930c1 61 Pfam PF00253 Ribosomal protein S14p/S29e 10 60 9.8E-24 T 15-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08750 0a4f01868f9dadf10dd3fa6e665930c1 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 15-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08750 0a4f01868f9dadf10dd3fa6e665930c1 61 SUPERFAMILY SSF57716 3 61 1.85E-21 T 15-10-2018 C2I28_24365 2e0f5a40f260377d3249dfc956dcc08e 306 Pfam PF00892 EamA-like transporter family 162 292 8.7E-21 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_24365 2e0f5a40f260377d3249dfc956dcc08e 306 Pfam PF00892 EamA-like transporter family 8 149 2.5E-19 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_24365 2e0f5a40f260377d3249dfc956dcc08e 306 SUPERFAMILY SSF103481 197 296 1.7E-11 T 15-10-2018 C2I28_24365 2e0f5a40f260377d3249dfc956dcc08e 306 SUPERFAMILY SSF103481 47 151 7.19E-8 T 15-10-2018 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 SUPERFAMILY SSF50494 86 303 1.79E-56 T 15-10-2018 IPR009003 Peptidase S1, PA clan C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 Gene3D G3DSA:2.40.10.10 73 185 2.4E-25 T 15-10-2018 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 Pfam PF13365 Trypsin-like peptidase domain 122 269 6.8E-33 T 15-10-2018 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 Gene3D G3DSA:2.30.42.10 307 410 6.1E-24 T 15-10-2018 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 SUPERFAMILY SSF50156 288 405 2.1E-19 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 Gene3D G3DSA:2.40.10.10 187 306 6.9E-40 T 15-10-2018 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 Pfam PF13180 PDZ domain 307 405 1.4E-19 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 2.5E-35 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 PRINTS PR00834 HtrA/DegQ protease family signature 196 220 2.5E-35 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 PRINTS PR00834 HtrA/DegQ protease family signature 134 146 2.5E-35 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 PRINTS PR00834 HtrA/DegQ protease family signature 262 279 2.5E-35 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 PRINTS PR00834 HtrA/DegQ protease family signature 155 175 2.5E-35 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 PRINTS PR00834 HtrA/DegQ protease family signature 353 365 2.5E-35 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_07850 9950f27351d5c4ef366536fa08bc5ace 410 SMART SM00228 307 396 2.0E-8 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 SUPERFAMILY SSF53633 11 267 2.36E-68 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 ProSitePatterns PS00902 Glutamate 5-kinase signature. 217 234 - T 15-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 PIRSF PIRSF000729 6 274 2.9E-96 T 15-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 TIGRFAM TIGR01027 proB: glutamate 5-kinase 11 270 5.9E-95 T 15-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 Hamap MF_00456 Glutamate 5-kinase [proB]. 11 271 37.235 T 15-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 1.1E-52 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 PRINTS PR00474 Glutamate 5-kinase family signature 82 110 1.1E-52 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 PRINTS PR00474 Glutamate 5-kinase family signature 219 239 1.1E-52 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 PRINTS PR00474 Glutamate 5-kinase family signature 48 62 1.1E-52 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 PRINTS PR00474 Glutamate 5-kinase family signature 122 143 1.1E-52 T 15-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 Gene3D G3DSA:3.40.1160.10 1 273 1.9E-91 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_07765 c5811e4e61a467e31f47febda337e0be 274 Pfam PF00696 Amino acid kinase family 11 245 2.8E-36 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 PIRSF PIRSF002939 2 216 1.1E-95 T 15-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 Pfam PF08281 Sigma-70, region 4 161 205 1.9E-11 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 SUPERFAMILY SSF88946 16 105 2.49E-23 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 SUPERFAMILY SSF88659 123 209 2.09E-10 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 Pfam PF04542 Sigma-70 region 2 36 105 2.9E-14 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 32 205 3.7E-25 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_00695 bc9194ece3a54a9c1e931b17355c2f80 216 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 208 8.8E-94 T 15-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_05550 1c9b34e6badfc4abe0527123e3f15f94 266 Gene3D G3DSA:3.40.50.10330 39 266 6.7E-76 T 15-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I28_05550 1c9b34e6badfc4abe0527123e3f15f94 266 Gene3D G3DSA:2.60.200.30 108 244 6.7E-76 T 15-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I28_05550 1c9b34e6badfc4abe0527123e3f15f94 266 Pfam PF01513 ATP-NAD kinase 40 251 4.4E-19 T 15-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I28_05550 1c9b34e6badfc4abe0527123e3f15f94 266 SUPERFAMILY SSF111331 9 265 5.72E-57 T 15-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I28_05550 1c9b34e6badfc4abe0527123e3f15f94 266 Hamap MF_00361 NAD kinase [nadK]. 4 266 21.29 T 15-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I28_09535 e5280eb888848ee6a7a149f2cbb32c64 485 Pfam PF01425 Amidase 24 465 4.1E-163 T 15-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_09535 e5280eb888848ee6a7a149f2cbb32c64 485 Gene3D G3DSA:3.90.1300.10 2 485 1.7E-201 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_09535 e5280eb888848ee6a7a149f2cbb32c64 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 96.438 T 15-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_09535 e5280eb888848ee6a7a149f2cbb32c64 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 15-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 C2I28_09535 e5280eb888848ee6a7a149f2cbb32c64 485 SUPERFAMILY SSF75304 1 483 4.45E-170 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_09535 e5280eb888848ee6a7a149f2cbb32c64 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.3E-206 T 15-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 Gene3D G3DSA:1.10.10.10 1 84 3.0E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 SUPERFAMILY SSF46785 1 84 4.66E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 SUPERFAMILY SSF53850 88 296 5.16E-41 T 15-10-2018 C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-9 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-9 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-9 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 Pfam PF03466 LysR substrate binding domain 88 290 7.2E-46 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 Gene3D G3DSA:3.40.190.290 90 297 3.5E-53 T 15-10-2018 C2I28_18290 9baec5bbfa988aa7ed0770a20019ae33 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.7E-21 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 SMART SM00962 169 360 1.2E-49 T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 SUPERFAMILY SSF52540 169 359 2.65E-30 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 SMART SM00382 168 315 8.6E-4 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 256 6.0E-63 T 15-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 Gene3D G3DSA:1.20.120.1380 119 350 2.6E-72 T 15-10-2018 C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 Gene3D G3DSA:3.40.50.300 165 348 2.6E-72 T 15-10-2018 C2I28_02430 16f7d1d0ccbe081991b2b9e5f46a429e 365 Pfam PF00448 SRP54-type protein, GTPase domain 171 359 1.3E-42 T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 SUPERFAMILY SSF56059 1 341 3.77E-94 T 15-10-2018 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 Pfam PF00391 PEP-utilising enzyme, mobile domain 792 863 1.0E-21 T 15-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 Gene3D G3DSA:3.30.1490.20 1 184 1.1E-68 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 Gene3D G3DSA:3.50.30.10 766 867 6.3E-31 T 15-10-2018 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 315 4.5E-91 T 15-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 SUPERFAMILY SSF52009 758 866 1.1E-27 T 15-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 C2I28_17055 b1aa1305f608700078dcf38faa0ae137 868 Gene3D G3DSA:3.30.470.20 185 314 5.2E-43 T 15-10-2018 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 119 1.0E-25 T 15-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 120 6.9E-44 T 15-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 118 26.143 T 15-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 SUPERFAMILY SSF56214 1 117 5.49E-37 T 15-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 118 8.8E-35 T 15-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 113 2.2E-23 T 15-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I28_09130 b869337d6f74aa765f70097f71a922b2 121 Gene3D G3DSA:3.90.470.20 1 121 1.3E-41 T 15-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 Gene3D G3DSA:3.40.47.10 220 359 2.1E-41 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 PIRSF PIRSF000451 1 361 3.5E-121 T 15-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 SUPERFAMILY SSF53901 221 360 9.6E-38 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 SUPERFAMILY SSF53901 3 210 1.02E-44 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 64 206 1.0E-17 T 15-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 Gene3D G3DSA:3.40.47.10 1 211 5.9E-60 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_15300 c269190cf4527bfbb63be3f2710097b3 361 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 224 358 5.5E-20 T 15-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal C2I28_19930 5ff7dc4677e23f828a383dfb2a44abee 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_19930 5ff7dc4677e23f828a383dfb2a44abee 485 Pfam PF00171 Aldehyde dehydrogenase family 19 481 3.8E-160 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_19930 5ff7dc4677e23f828a383dfb2a44abee 485 Gene3D G3DSA:3.40.309.10 259 450 4.2E-161 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_19930 5ff7dc4677e23f828a383dfb2a44abee 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_19930 5ff7dc4677e23f828a383dfb2a44abee 485 Gene3D G3DSA:3.40.605.10 15 479 4.2E-161 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_19930 5ff7dc4677e23f828a383dfb2a44abee 485 SUPERFAMILY SSF53720 6 485 2.23E-156 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.1E-16 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 SUPERFAMILY SSF46785 5 61 4.73E-15 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 Gene3D G3DSA:1.10.10.10 1 55 2.3E-5 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 SMART SM00420 6 58 8.0E-18 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.9E-8 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.9E-8 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 15-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 SUPERFAMILY SSF100950 74 231 7.95E-33 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 SMART SM01134 73 231 8.3E-64 T 15-10-2018 C2I28_18480 398109d3c7d6e8ca50e2c8966d7bd2eb 250 Pfam PF00455 DeoR C terminal sensor domain 75 229 8.6E-47 T 15-10-2018 IPR014036 DeoR C-terminal sensor domain C2I28_11370 ae7fe8a08c7f30bccc3603a4f13879c4 394 Pfam PF00149 Calcineurin-like phosphoesterase 1 224 3.6E-14 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_11370 ae7fe8a08c7f30bccc3603a4f13879c4 394 Gene3D G3DSA:3.60.21.10 1 273 6.1E-80 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_11370 ae7fe8a08c7f30bccc3603a4f13879c4 394 SUPERFAMILY SSF56300 1 332 3.23E-56 T 15-10-2018 C2I28_11370 ae7fe8a08c7f30bccc3603a4f13879c4 394 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 364 5.4E-8 T 15-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain C2I28_11370 ae7fe8a08c7f30bccc3603a4f13879c4 394 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 2.5E-75 T 15-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 C2I28_05545 08d93905a22a85ab6230e9f74dc3c407 336 Pfam PF01343 Peptidase family S49 133 283 2.9E-57 T 15-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 C2I28_05545 08d93905a22a85ab6230e9f74dc3c407 336 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 60 280 2.3E-83 T 15-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 C2I28_05545 08d93905a22a85ab6230e9f74dc3c407 336 Gene3D G3DSA:3.40.1750.20 173 239 2.2E-87 T 15-10-2018 C2I28_05545 08d93905a22a85ab6230e9f74dc3c407 336 SUPERFAMILY SSF52096 57 270 6.46E-42 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_05545 08d93905a22a85ab6230e9f74dc3c407 336 Gene3D G3DSA:3.90.226.10 62 276 2.2E-87 T 15-10-2018 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 Gene3D G3DSA:3.40.190.290 91 290 2.2E-44 T 15-10-2018 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 SUPERFAMILY SSF46785 3 111 2.73E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.4E-18 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 SUPERFAMILY SSF53850 89 289 5.43E-43 T 15-10-2018 C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 Gene3D G3DSA:1.10.10.10 1 90 7.7E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19415 fdee2edc14ce658d5d0441aabe228952 290 Pfam PF03466 LysR substrate binding domain 88 289 1.4E-48 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_16445 1fa80ee75c78cdc97f6511f38f5a45a0 257 Pfam PF03741 Integral membrane protein TerC family 15 207 5.9E-49 T 15-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I28_16445 1fa80ee75c78cdc97f6511f38f5a45a0 257 SUPERFAMILY SSF103473 9 247 5.62E-5 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_16445 1fa80ee75c78cdc97f6511f38f5a45a0 257 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 246 4.9E-81 T 15-10-2018 IPR022493 Integral membrane YkoY C2I28_25085 aadef5041a01f873c454d9a973b18717 283 Gene3D G3DSA:3.40.50.300 1 242 3.0E-51 T 15-10-2018 C2I28_25085 aadef5041a01f873c454d9a973b18717 283 SMART SM00382 29 208 7.6E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_25085 aadef5041a01f873c454d9a973b18717 283 SUPERFAMILY SSF52540 3 223 7.07E-50 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_25085 aadef5041a01f873c454d9a973b18717 283 Pfam PF00005 ABC transporter 20 158 7.7E-25 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15135 397366730d11902699ca53ced30e6133 181 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 7 178 3.6E-41 T 15-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 C2I28_15135 397366730d11902699ca53ced30e6133 181 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 177 2.1E-26 T 15-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I28_08455 33e933ad3ea69d0858750cc44c417cb8 179 SUPERFAMILY SSF53271 3 177 1.57E-58 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_08455 33e933ad3ea69d0858750cc44c417cb8 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 2.5E-69 T 15-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 C2I28_08455 33e933ad3ea69d0858750cc44c417cb8 179 Pfam PF00156 Phosphoribosyl transferase domain 13 159 1.2E-24 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_08455 33e933ad3ea69d0858750cc44c417cb8 179 Gene3D G3DSA:3.40.50.2020 1 179 1.6E-66 T 15-10-2018 C2I28_05960 2164910a53cab1e01cae01dd6647d5d5 93 PIRSF PIRSF020408 2 93 4.4E-33 T 15-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 C2I28_05960 2164910a53cab1e01cae01dd6647d5d5 93 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 92 2.1E-19 T 15-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 Pfam PF00270 DEAD/DEAH box helicase 259 415 1.4E-16 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 Pfam PF17191 RecG wedge domain 8 164 1.1E-16 T 15-10-2018 IPR033454 RecG, wedge domain C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 Gene3D G3DSA:3.40.50.300 441 613 1.1E-56 T 15-10-2018 C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 Pfam PF00271 Helicase conserved C-terminal domain 452 572 1.1E-19 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 648 3.0E-248 T 15-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 Gene3D G3DSA:3.40.50.300 197 434 2.7E-85 T 15-10-2018 C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 SUPERFAMILY SSF52540 173 436 1.51E-61 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 Gene3D G3DSA:2.40.50.140 45 140 1.4E-10 T 15-10-2018 C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 SUPERFAMILY SSF52540 436 640 1.54E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 SUPERFAMILY SSF50249 7 167 6.08E-27 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 SMART SM00490 492 573 2.4E-21 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 SMART SM00490 323 401 0.53 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_02690 5a541ab06c044b3ffc0c12cf0c4af328 682 SMART SM00487 253 442 1.1E-31 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 Gene3D G3DSA:3.40.50.720 3 247 2.4E-76 T 15-10-2018 C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.0E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.0E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 6.0E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 6.0E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.0E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.0E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 2.6E-57 T 15-10-2018 C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.8E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.8E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.8E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25270 765cc0e6a9dd94951852fd3b82856869 247 SUPERFAMILY SSF51735 5 247 2.09E-74 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Gene3D G3DSA:1.20.140.10 252 422 9.9E-52 T 15-10-2018 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Gene3D G3DSA:1.20.140.10 423 594 1.1E-56 T 15-10-2018 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Gene3D G3DSA:2.40.110.10 146 251 2.7E-35 T 15-10-2018 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 SUPERFAMILY SSF56645 25 263 3.66E-73 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 SUPERFAMILY SSF47203 257 422 8.38E-44 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 143 9.3E-30 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Gene3D G3DSA:1.10.540.10 1 145 2.3E-44 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 415 2.4E-33 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_06585 57392d5e18a77f8825288eb4dca9a962 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 1.1E-22 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_03350 d2bf99b09b6410d91bae8889ec7f0cc6 255 Gene3D G3DSA:3.60.21.10 43 224 3.0E-19 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_03350 d2bf99b09b6410d91bae8889ec7f0cc6 255 SUPERFAMILY SSF56300 41 253 4.98E-29 T 15-10-2018 C2I28_03350 d2bf99b09b6410d91bae8889ec7f0cc6 255 Pfam PF00149 Calcineurin-like phosphoesterase 45 200 9.5E-11 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_23750 28fa8be5007691dc2b9b29fb5e6f84a6 202 Gene3D G3DSA:1.20.120.80 15 201 4.4E-48 T 15-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23750 28fa8be5007691dc2b9b29fb5e6f84a6 202 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 12 201 3.7E-82 T 15-10-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 C2I28_23750 28fa8be5007691dc2b9b29fb5e6f84a6 202 SUPERFAMILY SSF81452 18 199 2.35E-49 T 15-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23750 28fa8be5007691dc2b9b29fb5e6f84a6 202 Pfam PF00510 Cytochrome c oxidase subunit III 23 198 1.5E-8 T 15-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 Pfam PF01614 Bacterial transcriptional regulator 122 245 3.1E-38 T 15-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 Gene3D G3DSA:1.10.10.10 2 72 6.6E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 SUPERFAMILY SSF46785 4 67 3.22E-13 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 Gene3D G3DSA:3.30.450.40 80 250 6.0E-54 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 Pfam PF09339 IclR helix-turn-helix domain 7 56 2.8E-9 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 SMART SM00346 4 94 0.0057 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_12730 40c8b30147b3049eb9c284167f1f4ddc 251 SUPERFAMILY SSF55781 84 247 2.8E-45 T 15-10-2018 C2I28_01000 64f951522d3dd2a0b00148f1f3977053 508 Gene3D G3DSA:3.90.550.10 242 492 3.7E-18 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_01000 64f951522d3dd2a0b00148f1f3977053 508 Gene3D G3DSA:3.90.550.10 1 180 1.0E-23 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_01000 64f951522d3dd2a0b00148f1f3977053 508 Pfam PF00535 Glycosyl transferase family 2 4 108 2.2E-19 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_01000 64f951522d3dd2a0b00148f1f3977053 508 Pfam PF00535 Glycosyl transferase family 2 262 382 3.5E-8 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_01000 64f951522d3dd2a0b00148f1f3977053 508 SUPERFAMILY SSF53448 260 418 1.95E-14 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_01000 64f951522d3dd2a0b00148f1f3977053 508 SUPERFAMILY SSF53448 2 114 2.5E-24 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_22030 e82664ccda5cedbb863ce6dc5eb3b90c 333 Pfam PF11553 Protein of unknown function (DUF3231) 2 157 6.4E-27 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_22030 e82664ccda5cedbb863ce6dc5eb3b90c 333 Pfam PF11553 Protein of unknown function (DUF3231) 171 330 3.1E-45 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_22030 e82664ccda5cedbb863ce6dc5eb3b90c 333 Gene3D G3DSA:1.20.1260.10 1 145 3.6E-8 T 15-10-2018 IPR012347 Ferritin-like C2I28_14960 565f5726086247b8234fe4153930fcaf 109 SUPERFAMILY SSF101386 4 104 3.76E-27 T 15-10-2018 C2I28_14960 565f5726086247b8234fe4153930fcaf 109 PIRSF PIRSF029904 1 109 5.2E-55 T 15-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD C2I28_14960 565f5726086247b8234fe4153930fcaf 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 2.4E-19 T 15-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I28_14960 565f5726086247b8234fe4153930fcaf 109 Gene3D G3DSA:1.10.287.1080 1 109 3.7E-36 T 15-10-2018 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 SUPERFAMILY SSF56003 113 767 1.11E-154 T 15-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 709 1.7E-137 T 15-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 121 5.9E-27 T 15-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Gene3D G3DSA:3.30.365.10 122 361 7.5E-100 T 15-10-2018 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Gene3D G3DSA:3.30.365.10 451 624 1.4E-98 T 15-10-2018 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 SUPERFAMILY SSF54665 2 141 4.84E-41 T 15-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 SMART SM01008 18 121 5.3E-39 T 15-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Gene3D G3DSA:3.30.365.10 16 285 7.5E-100 T 15-10-2018 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Gene3D G3DSA:3.90.1170.50 33 121 7.5E-100 T 15-10-2018 C2I28_20955 864a50d97416f2edd08de6bc83db9edf 776 Gene3D G3DSA:3.30.365.10 372 762 1.4E-98 T 15-10-2018 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Pfam PF16326 ABC transporter C-terminal domain 558 624 1.3E-13 T 15-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Pfam PF00005 ABC transporter 336 469 1.1E-22 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Gene3D G3DSA:3.40.50.300 1 281 7.9E-70 T 15-10-2018 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Gene3D G3DSA:1.10.287.380 551 627 5.7E-8 T 15-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 SMART SM00382 343 514 5.8E-9 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 SMART SM00382 28 231 5.3E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Gene3D G3DSA:3.40.50.300 282 550 9.0E-62 T 15-10-2018 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Pfam PF12848 ABC transporter 226 295 1.9E-12 T 15-10-2018 IPR032781 ABC-transporter extension domain C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 Pfam PF00005 ABC transporter 20 187 6.0E-28 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 SUPERFAMILY SSF52540 313 513 7.51E-47 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17750 715fc34df2cd9113fb9acbc59b74b545 632 SUPERFAMILY SSF52540 4 238 1.42E-51 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06805 1aabc1bdb4294fb224e15aaadeb3b046 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 9.3E-22 T 15-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I28_06805 1aabc1bdb4294fb224e15aaadeb3b046 77 Pfam PF03840 Preprotein translocase SecG subunit 4 74 2.4E-20 T 15-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I28_06805 1aabc1bdb4294fb224e15aaadeb3b046 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.4E-11 T 15-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I28_06805 1aabc1bdb4294fb224e15aaadeb3b046 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 3.4E-11 T 15-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I28_06805 1aabc1bdb4294fb224e15aaadeb3b046 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.4E-11 T 15-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SMART SM00388 250 313 2.2E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 121 240 6.7E-16 T 15-10-2018 IPR000014 PAS domain C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Gene3D G3DSA:3.30.450.20 1 103 3.4E-5 T 15-10-2018 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 309 1.7E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Gene3D G3DSA:3.30.450.20 118 237 3.2E-17 T 15-10-2018 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SMART SM00387 355 460 3.8E-30 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Pfam PF00989 PAS fold 124 231 3.1E-11 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Pfam PF13426 PAS domain 17 94 0.44 T 15-10-2018 IPR000014 PAS domain C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SUPERFAMILY SSF55874 305 458 7.99E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 6.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 6.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 6.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 6.4E-14 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SUPERFAMILY SSF47384 245 310 3.53E-13 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SUPERFAMILY SSF55785 114 233 4.89E-16 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SMART SM00091 123 189 8.3E-10 T 15-10-2018 IPR000014 PAS domain C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SMART SM00091 5 72 51.0 T 15-10-2018 IPR000014 PAS domain C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Gene3D G3DSA:1.10.287.130 253 306 4.9E-18 T 15-10-2018 C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Gene3D G3DSA:3.30.565.10 307 458 1.1E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 457 2.7E-23 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01795 f19b87eb96b427b847d4e4b4573881ce 466 SUPERFAMILY SSF55785 2 52 5.76E-5 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_05525 e660ba9b6355b5990e5e093a0dc6358b 177 Pfam PF08534 Redoxin 30 170 2.4E-24 T 15-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 C2I28_05525 e660ba9b6355b5990e5e093a0dc6358b 177 Gene3D G3DSA:3.40.30.10 9 176 2.9E-49 T 15-10-2018 C2I28_05525 e660ba9b6355b5990e5e093a0dc6358b 177 Hamap MF_00269 Thiol peroxidase [tpx]. 14 174 37.969 T 15-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_05525 e660ba9b6355b5990e5e093a0dc6358b 177 ProSitePatterns PS01265 Tpx family signature. 94 105 - T 15-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_05525 e660ba9b6355b5990e5e093a0dc6358b 177 SUPERFAMILY SSF52833 15 171 9.81E-44 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 5.6E-23 T 15-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 5.6E-23 T 15-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 5.6E-23 T 15-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 Gene3D G3DSA:2.40.50.530 1 63 2.9E-22 T 15-10-2018 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 15-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.256 T 15-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 4.1E-26 T 15-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 Pfam PF01632 Ribosomal protein L35 2 62 7.4E-26 T 15-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_05310 831864fe81b0614ab32fbd52d601f589 66 SUPERFAMILY SSF143034 2 62 6.02E-22 T 15-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_11610 7284584694dae447e9fccbdcf3840e35 507 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 507 250.699 T 15-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11610 7284584694dae447e9fccbdcf3840e35 507 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 55 234 2.4E-35 T 15-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 C2I28_11610 7284584694dae447e9fccbdcf3840e35 507 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 9 503 3.3E-214 T 15-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11610 7284584694dae447e9fccbdcf3840e35 507 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 262 279 - T 15-10-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_11610 7284584694dae447e9fccbdcf3840e35 507 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 249 439 1.4E-36 T 15-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 C2I28_11610 7284584694dae447e9fccbdcf3840e35 507 PIRSF PIRSF006005 3 507 3.1E-221 T 15-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 C2I28_09640 2046a06f5d5c3c1aa25756be79e8a80a 216 SUPERFAMILY SSF161098 14 204 2.62E-44 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_09640 2046a06f5d5c3c1aa25756be79e8a80a 216 Gene3D G3DSA:1.10.3720.10 6 215 1.6E-53 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_09640 2046a06f5d5c3c1aa25756be79e8a80a 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 212 1.0E-18 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_09640 2046a06f5d5c3c1aa25756be79e8a80a 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 2.4E-29 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_22325 964c1d2a9e057f696f4917e1a3cf26c3 148 Pfam PF14328 Domain of unknown function (DUF4385) 4 145 1.9E-69 T 15-10-2018 IPR025494 Protein of unknown function DUF4385 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 Gene3D G3DSA:3.40.1030.10 77 330 3.3E-154 T 15-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 4.1E-23 T 15-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 PIRSF PIRSF000478 1 433 6.1E-172 T 15-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 SMART SM00941 345 419 1.2E-30 T 15-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 416 8.1E-27 T 15-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 Gene3D G3DSA:3.90.1170.30 331 417 3.3E-154 T 15-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 411 5.4E-185 T 15-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 2.8E-48 T 15-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 SUPERFAMILY SSF54680 332 432 7.72E-29 T 15-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 SUPERFAMILY SSF47648 1 69 4.32E-24 T 15-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 15-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 Gene3D G3DSA:1.20.970.10 1 67 7.7E-31 T 15-10-2018 C2I28_22100 133ee34e15ccbcef324ab91bbcb1b3b6 433 SUPERFAMILY SSF52418 69 329 1.96E-93 T 15-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 Gene3D G3DSA:3.40.630.10 344 485 6.8E-24 T 15-10-2018 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 102 120 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 160 178 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 451 473 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 364 382 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 207 224 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 429 445 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 81 100 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PRINTS PR00934 X-His dipeptidase (M25) signature 136 153 2.9E-52 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 SUPERFAMILY SSF53187 13 483 2.51E-56 T 15-10-2018 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 10 482 1.0E-182 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 Pfam PF01546 Peptidase family M20/M25/M40 73 481 8.7E-23 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 Pfam PF07687 Peptidase dimerisation domain 214 292 3.1E-6 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_19760 684c73566912f2a6d1061106dfb19863 486 PIRSF PIRSF016599 2 486 4.7E-186 T 15-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 C2I28_19760 684c73566912f2a6d1061106dfb19863 486 Gene3D G3DSA:3.40.630.10 2 227 2.1E-53 T 15-10-2018 C2I28_12425 e7c20af84f783a08ac6bba6732b9690c 311 Gene3D G3DSA:3.20.20.330 1 307 7.0E-115 T 15-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I28_12425 e7c20af84f783a08ac6bba6732b9690c 311 PIRSF PIRSF037505 3 243 1.1E-4 T 15-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 C2I28_12425 e7c20af84f783a08ac6bba6732b9690c 311 PIRSF PIRSF037505 274 309 4.0 T 15-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 C2I28_12425 e7c20af84f783a08ac6bba6732b9690c 311 Pfam PF02574 Homocysteine S-methyltransferase 14 307 1.4E-84 T 15-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 C2I28_12425 e7c20af84f783a08ac6bba6732b9690c 311 SUPERFAMILY SSF82282 10 310 6.41E-89 T 15-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I28_02285 2b2563a64cb2be6e137115cb5c67fc75 326 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 47 313 4.1E-132 T 15-10-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY C2I28_02285 2b2563a64cb2be6e137115cb5c67fc75 326 SUPERFAMILY SSF88713 103 313 1.16E-60 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_02285 2b2563a64cb2be6e137115cb5c67fc75 326 Gene3D G3DSA:3.20.20.370 115 322 1.6E-61 T 15-10-2018 C2I28_02285 2b2563a64cb2be6e137115cb5c67fc75 326 Pfam PF01522 Polysaccharide deacetylase 126 245 1.2E-31 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_09840 e9034fe0f22977fb2cb1ca605a733a55 165 ProDom PD090911 YUEC MEMBRANE TRANSMEMBRANE 15 134 5.0E-7 T 15-10-2018 IPR020212 ESX secretion system protein YueC C2I28_09840 e9034fe0f22977fb2cb1ca605a733a55 165 TIGRFAM TIGR03927 T7SS_EssA_Firm: type VII secretion protein EssA 17 154 1.4E-14 T 15-10-2018 IPR018920 ESAT-6 secretion machinery protein EssA/YueC C2I28_09840 e9034fe0f22977fb2cb1ca605a733a55 165 Pfam PF17355 Family of unknown function (DUF5383) 39 160 6.6E-41 T 15-10-2018 IPR020212 ESX secretion system protein YueC C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 SUPERFAMILY SSF55920 138 365 3.01E-78 T 15-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 139 1.6E-27 T 15-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 PRINTS PR00599 Methionine aminopeptidase-1 signature 317 329 1.5E-6 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 PRINTS PR00599 Methionine aminopeptidase-1 signature 219 235 1.5E-6 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 Gene3D G3DSA:3.90.230.10 140 365 5.0E-80 T 15-10-2018 C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 Gene3D G3DSA:3.40.350.10 1 139 1.7E-39 T 15-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 295 307 - T 15-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 SUPERFAMILY SSF53092 1 138 9.59E-33 T 15-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal C2I28_01165 61aad922eea8979e752c0f22f618cd27 366 Pfam PF00557 Metallopeptidase family M24 148 349 5.0E-63 T 15-10-2018 IPR000994 Peptidase M24 C2I28_09575 db211d15c5b13e404c07f52b22cdcdcc 76 Pfam PF12728 Helix-turn-helix domain 2 50 2.5E-7 T 15-10-2018 C2I28_09575 db211d15c5b13e404c07f52b22cdcdcc 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 6.6E-16 T 15-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 C2I28_00795 149ec4e3d12575152c689891e61038bf 244 Pfam PF13489 Methyltransferase domain 37 208 5.4E-17 T 15-10-2018 C2I28_00795 149ec4e3d12575152c689891e61038bf 244 Gene3D G3DSA:3.40.50.150 31 243 1.2E-50 T 15-10-2018 C2I28_00795 149ec4e3d12575152c689891e61038bf 244 SUPERFAMILY SSF53335 8 213 4.48E-35 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 831 838 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 SUPERFAMILY SSF52440 554 671 2.73E-43 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.9E-62 T 15-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 543 2.0E-37 T 15-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Gene3D G3DSA:1.10.1030.10 403 549 3.8E-42 T 15-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 SUPERFAMILY SSF56059 669 926 6.89E-76 T 15-10-2018 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Gene3D G3DSA:3.40.50.20 1 116 1.3E-47 T 15-10-2018 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Gene3D G3DSA:3.30.470.20 120 401 5.7E-122 T 15-10-2018 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 973 0.0 T 15-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 333 2.1E-80 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 868 1.0E-31 T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Gene3D G3DSA:3.30.1490.20 682 749 2.5E-81 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1021 12.266 T 15-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Gene3D G3DSA:3.40.50.20 550 658 2.3E-42 T 15-10-2018 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 SUPERFAMILY SSF52440 1 127 1.02E-49 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 15-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 SUPERFAMILY SSF56059 129 399 4.07E-107 T 15-10-2018 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 Gene3D G3DSA:3.30.470.20 663 924 2.5E-81 T 15-10-2018 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 SUPERFAMILY SSF48108 394 549 4.18E-46 T 15-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_11570 1e10e135ee79898de3552491bbc12429 1036 SMART SM01096 420 543 2.2E-58 T 15-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 Pfam PF01022 Bacterial regulatory protein, arsR family 23 70 8.5E-18 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 SMART SM00418 16 95 5.6E-30 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 SUPERFAMILY SSF46785 11 91 1.14E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 5.2E-18 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 5.2E-18 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 5.2E-18 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 49 5.2E-18 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 40 58 - T 15-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 C2I28_16705 55d1fc0eb36857a22a7582bf59274c8e 109 Gene3D G3DSA:1.10.10.10 2 95 3.1E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03450 78881d35aab084500b1545a4d13db0a3 251 Pfam PF02616 Segregation and condensation protein ScpA 20 243 1.2E-53 T 15-10-2018 IPR003768 Segregation and condensation protein A C2I28_03450 78881d35aab084500b1545a4d13db0a3 251 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 246 25.882 T 15-10-2018 IPR003768 Segregation and condensation protein A C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 SUPERFAMILY SSF69754 3 108 5.1E-36 T 15-10-2018 IPR036567 Ribosome hibernation promotion factor-like C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 94 4.0E-32 T 15-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 124 179 1.2E-28 T 15-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 Gene3D G3DSA:3.30.160.100 2 98 2.3E-34 T 15-10-2018 IPR036567 Ribosome hibernation promotion factor-like C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 Gene3D G3DSA:3.30.505.50 137 183 3.6E-27 T 15-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 101 1.3E-34 T 15-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 C2I28_07070 ecd5f04027781afeec04bfef5ecae632 183 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 183 25.536 T 15-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid C2I28_04750 ecd7f63b33b41d4f6ddccaf39bc9f33c 379 SUPERFAMILY SSF51713 2 369 3.01E-163 T 15-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I28_04750 ecd7f63b33b41d4f6ddccaf39bc9f33c 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 1.1E-92 T 15-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I28_04750 ecd7f63b33b41d4f6ddccaf39bc9f33c 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.933 T 15-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I28_04750 ecd7f63b33b41d4f6ddccaf39bc9f33c 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 6.0E-176 T 15-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I28_04750 ecd7f63b33b41d4f6ddccaf39bc9f33c 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 372 2.0E-186 T 15-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I28_04750 ecd7f63b33b41d4f6ddccaf39bc9f33c 379 Gene3D G3DSA:3.20.20.105 2 372 8.8E-172 T 15-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 396 1.2E-152 T 15-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 Gene3D G3DSA:3.40.50.1950 1 188 4.3E-61 T 15-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 Gene3D G3DSA:3.40.50.10300 189 405 2.5E-84 T 15-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 SUPERFAMILY SSF102645 188 401 5.23E-74 T 15-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 SUPERFAMILY SSF52507 1 177 6.28E-62 T 15-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 191 370 1.8E-72 T 15-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 C2I28_02780 0134d4e43759b840872288918cb85eb2 405 Pfam PF02441 Flavoprotein 5 174 7.2E-46 T 15-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 C2I28_17835 209047079ac9975389b612689d1a9ce4 108 Gene3D G3DSA:1.10.1660.10 6 90 6.4E-26 T 15-10-2018 C2I28_17835 209047079ac9975389b612689d1a9ce4 108 Pfam PF13411 MerR HTH family regulatory protein 14 80 1.1E-15 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_17835 209047079ac9975389b612689d1a9ce4 108 SUPERFAMILY SSF46955 14 100 9.16E-18 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_17835 209047079ac9975389b612689d1a9ce4 108 SMART SM00422 14 82 9.5E-18 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_21285 3c7fa918ca8b0049bfa675047f1f59a0 483 PIRSF PIRSF037227 1 474 4.1E-207 T 15-10-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B C2I28_21285 3c7fa918ca8b0049bfa675047f1f59a0 483 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 425 6.3E-88 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_21285 3c7fa918ca8b0049bfa675047f1f59a0 483 Pfam PF07687 Peptidase dimerisation domain 185 279 7.4E-6 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_21285 3c7fa918ca8b0049bfa675047f1f59a0 483 Pfam PF01546 Peptidase family M20/M25/M40 98 184 4.9E-7 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_21285 3c7fa918ca8b0049bfa675047f1f59a0 483 SUPERFAMILY SSF53187 6 441 1.64E-56 T 15-10-2018 C2I28_21285 3c7fa918ca8b0049bfa675047f1f59a0 483 SUPERFAMILY SSF55031 187 292 6.13E-19 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_18495 466568df4dfebd4c45cb14249857873d 460 Gene3D G3DSA:1.20.120.1320 39 135 1.6E-74 T 15-10-2018 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 2.4E-84 T 15-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 Gene3D G3DSA:3.40.1160.10 3 287 1.6E-74 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_18495 466568df4dfebd4c45cb14249857873d 460 SUPERFAMILY SSF55021 372 450 2.5E-21 T 15-10-2018 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 Gene3D G3DSA:3.30.2130.10 290 454 7.8E-52 T 15-10-2018 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 Pfam PF13840 ACT domain 380 445 4.2E-9 T 15-10-2018 IPR027795 CASTOR, ACT domain C2I28_18495 466568df4dfebd4c45cb14249857873d 460 Pfam PF00696 Amino acid kinase family 2 276 8.3E-39 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 SUPERFAMILY SSF53633 1 290 3.4E-65 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_18495 466568df4dfebd4c45cb14249857873d 460 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 15-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 PIRSF PIRSF000726 1 455 1.9E-82 T 15-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 C2I28_18495 466568df4dfebd4c45cb14249857873d 460 SUPERFAMILY SSF55021 297 359 2.52E-8 T 15-10-2018 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SMART SM00322 302 358 9.6 T 15-10-2018 IPR004087 K Homology domain GO:0003676 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SMART SM00322 229 301 5.5E-4 T 15-10-2018 IPR004087 K Homology domain GO:0003676 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 8.9E-131 T 15-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 367 30.529 T 15-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SUPERFAMILY SSF50249 132 198 7.8E-20 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Pfam PF13184 NusA-like KH domain 229 296 3.1E-27 T 15-10-2018 IPR025249 KH domain, NusA-like GO:0003723 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Gene3D G3DSA:3.30.1480.10 1 124 1.2E-49 T 15-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SUPERFAMILY SSF54814 278 342 3.99E-17 T 15-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Pfam PF08529 NusA N-terminal domain 4 123 8.9E-44 T 15-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SUPERFAMILY SSF69705 1 126 1.09E-43 T 15-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Gene3D G3DSA:3.30.300.20 198 276 1.0E-33 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SMART SM00316 133 199 5.7E-9 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Gene3D G3DSA:3.30.300.20 277 368 9.3E-34 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Pfam PF00575 S1 RNA binding domain 132 195 2.4E-12 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 Gene3D G3DSA:2.40.50.140 136 197 1.0E-25 T 15-10-2018 C2I28_02335 757307bb6e6cc2241004c2be39e45625 370 SUPERFAMILY SSF54814 199 277 1.96E-29 T 15-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I28_14360 d8d3a15fd8f1d09dcb35daf40dcc3889 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 560 3.4E-218 T 15-10-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related C2I28_14360 d8d3a15fd8f1d09dcb35daf40dcc3889 564 Gene3D G3DSA:1.10.1370.30 1 564 1.5E-212 T 15-10-2018 C2I28_14360 d8d3a15fd8f1d09dcb35daf40dcc3889 564 SUPERFAMILY SSF55486 34 560 1.71E-124 T 15-10-2018 C2I28_20510 a9f89fbefbadc427ee6ec50f96543925 282 Pfam PF04072 Leucine carboxyl methyltransferase 10 184 9.8E-41 T 15-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 C2I28_20510 a9f89fbefbadc427ee6ec50f96543925 282 Gene3D G3DSA:3.40.50.150 2 275 2.4E-52 T 15-10-2018 C2I28_20510 a9f89fbefbadc427ee6ec50f96543925 282 SUPERFAMILY SSF53335 6 280 4.9E-54 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_20510 a9f89fbefbadc427ee6ec50f96543925 282 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 9 262 6.9E-52 T 15-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 Gene3D G3DSA:3.30.1390.20 1 59 5.5E-28 T 15-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 3.1E-21 T 15-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 PIRSF PIRSF002211 1 60 5.8E-30 T 15-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 SUPERFAMILY SSF55129 3 59 6.02E-22 T 15-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 15-10-2018 IPR018038 Ribosomal protein L30, conserved site C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 20.558 T 15-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08775 142765b9cc1439a371b48efa0ad6b166 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 2.5E-26 T 15-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 SUPERFAMILY SSF53613 1 301 1.87E-67 T 15-10-2018 IPR029056 Ribokinase-like C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 Pfam PF00294 pfkB family carbohydrate kinase 8 281 1.6E-56 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 PIRSF PIRSF000535 1 303 1.9E-88 T 15-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 1.2E-109 T 15-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 8.3E-110 T 15-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 Gene3D G3DSA:3.40.1190.20 1 304 4.3E-108 T 15-10-2018 IPR029056 Ribokinase-like C2I28_18485 511313ee45cfa12a7827146c098f52ea 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 Gene3D G3DSA:3.40.50.620 1 164 1.4E-56 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 SUPERFAMILY SSF52374 4 157 1.75E-42 T 15-10-2018 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 35.643 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 1.7E-16 T 15-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 77 7.0E-4 T 15-10-2018 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.9E-51 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.9E-51 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.9E-51 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.9E-51 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.9E-51 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 1.9E-61 T 15-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 C2I28_03070 d99193340e5f40a0814bdc658f8047e2 164 Pfam PF01467 Cytidylyltransferase-like 7 134 6.2E-18 T 15-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 SUPERFAMILY SSF51735 120 291 2.84E-34 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 Gene3D G3DSA:3.90.180.10 20 329 1.2E-116 T 15-10-2018 C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 SUPERFAMILY SSF50129 5 148 3.96E-40 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 Gene3D G3DSA:3.40.50.720 129 298 1.2E-116 T 15-10-2018 C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 SMART SM00829 23 328 6.7E-5 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 Pfam PF00107 Zinc-binding dehydrogenase 162 272 1.2E-13 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 89 1.6E-4 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_20500 cdb130b3705505ebdda8f2d83ab7fd2f 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 330 1.8E-137 T 15-10-2018 IPR014188 Acrylyl-CoA reductase AcuI C2I28_00830 02108c21ea2673bf71ee87f6e8885b2f 160 Gene3D G3DSA:1.20.120.450 1 149 1.1E-30 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_00830 02108c21ea2673bf71ee87f6e8885b2f 160 SUPERFAMILY SSF109854 12 148 3.97E-23 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_00830 02108c21ea2673bf71ee87f6e8885b2f 160 Pfam PF12867 DinB superfamily 19 145 3.4E-10 T 15-10-2018 IPR024775 DinB-like domain C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 420 42.417 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 419 8.2E-168 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 128 154 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 193 218 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 354 372 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 244 263 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 313 338 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 163 189 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PRINTS PR00083 Histidinol dehydrogenase signature 222 243 3.1E-88 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 SUPERFAMILY SSF53720 21 420 7.26E-85 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 222 254 - T 15-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 Pfam PF00815 Histidinol dehydrogenase 20 420 3.1E-170 T 15-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 PIRSF PIRSF000099 2 422 2.5E-170 T 15-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 Gene3D G3DSA:3.40.50.1980 226 342 1.9E-125 T 15-10-2018 C2I28_06925 02ba9ae744644f8a77524e4741a5d416 422 Gene3D G3DSA:3.40.50.1980 26 225 1.9E-125 T 15-10-2018 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 SUPERFAMILY SSF51690 140 477 1.62E-132 T 15-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 157 339 6.7E-11 T 15-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 SUPERFAMILY SSF54675 6 139 4.32E-48 T 15-10-2018 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 Gene3D G3DSA:3.20.20.70 152 319 9.8E-207 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 466 1.1E-183 T 15-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 Gene3D G3DSA:3.20.140.10 11 471 9.8E-207 T 15-10-2018 C2I28_19035 7883fe3a110b4f3c9db01c4aa8cf8fa4 489 PIRSF PIRSF000484 3 481 4.7E-153 T 15-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 C2I28_24945 c2decd08770d5af07d3824f20f4e6df6 404 Gene3D G3DSA:3.40.50.1100 111 207 9.4E-106 T 15-10-2018 C2I28_24945 c2decd08770d5af07d3824f20f4e6df6 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 379 1.5E-60 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_24945 c2decd08770d5af07d3824f20f4e6df6 404 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 15-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I28_24945 c2decd08770d5af07d3824f20f4e6df6 404 SUPERFAMILY SSF53686 4 388 5.89E-87 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_24945 c2decd08770d5af07d3824f20f4e6df6 404 Gene3D G3DSA:3.40.50.1100 60 385 9.4E-106 T 15-10-2018 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 Pfam PF00083 Sugar (and other) transporter 12 440 4.4E-110 T 15-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 Gene3D G3DSA:1.20.1250.20 5 439 4.1E-118 T 15-10-2018 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 9 437 1.3E-106 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 PRINTS PR00171 Sugar transporter signature 17 27 1.8E-24 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 PRINTS PR00171 Sugar transporter signature 100 119 1.8E-24 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 PRINTS PR00171 Sugar transporter signature 342 363 1.8E-24 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 PRINTS PR00171 Sugar transporter signature 253 263 1.8E-24 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 PRINTS PR00171 Sugar transporter signature 365 377 1.8E-24 T 15-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 C2I28_25565 a39aef6e2a1a4d777bfe66f5510ee529 459 SUPERFAMILY SSF103473 7 438 5.23E-75 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_25345 b26f8c56ddb72ab41f13abd785508aee 503 SMART SM00283 225 500 2.4E-64 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_25345 b26f8c56ddb72ab41f13abd785508aee 503 SUPERFAMILY SSF58104 231 497 4.05E-63 T 15-10-2018 C2I28_25345 b26f8c56ddb72ab41f13abd785508aee 503 Gene3D G3DSA:1.10.287.950 169 500 1.7E-65 T 15-10-2018 C2I28_25345 b26f8c56ddb72ab41f13abd785508aee 503 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 269 452 2.3E-45 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_00725 6dd2b2c4f3935e653fa115da7f45e97c 464 Gene3D G3DSA:1.20.1740.10 7 461 1.6E-74 T 15-10-2018 C2I28_00725 6dd2b2c4f3935e653fa115da7f45e97c 464 Pfam PF00324 Amino acid permease 16 453 7.8E-121 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_00725 6dd2b2c4f3935e653fa115da7f45e97c 464 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_00725 6dd2b2c4f3935e653fa115da7f45e97c 464 PIRSF PIRSF006060 1 462 1.4E-82 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_06915 70b74d8fc0e3b1a5e7c5004a12bf5dca 215 Pfam PF00117 Glutamine amidotransferase class-I 4 199 4.6E-23 T 15-10-2018 IPR017926 Glutamine amidotransferase C2I28_06915 70b74d8fc0e3b1a5e7c5004a12bf5dca 215 Gene3D G3DSA:3.40.50.880 1 214 4.9E-74 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_06915 70b74d8fc0e3b1a5e7c5004a12bf5dca 215 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 204 36.588 T 15-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 C2I28_06915 70b74d8fc0e3b1a5e7c5004a12bf5dca 215 PIRSF PIRSF000495 1 207 4.0E-77 T 15-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 C2I28_06915 70b74d8fc0e3b1a5e7c5004a12bf5dca 215 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 203 4.6E-71 T 15-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 C2I28_06915 70b74d8fc0e3b1a5e7c5004a12bf5dca 215 SUPERFAMILY SSF52317 2 206 1.67E-55 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Pfam PF03129 Anticodon binding domain 470 561 1.4E-21 T 15-10-2018 IPR004154 Anticodon-binding C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 SUPERFAMILY SSF55681 9 473 2.49E-105 T 15-10-2018 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 453 8.0E-61 T 15-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 SUPERFAMILY SSF52954 458 564 2.11E-30 T 15-10-2018 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 40.997 T 15-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Pfam PF04073 Aminoacyl-tRNA editing domain 257 372 9.7E-30 T 15-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 PIRSF PIRSF001535 1 565 2.6E-266 T 15-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Gene3D G3DSA:3.90.960.10 240 384 5.6E-254 T 15-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.6E-17 T 15-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.6E-17 T 15-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.6E-17 T 15-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.6E-17 T 15-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 SUPERFAMILY SSF55826 218 373 7.98E-32 T 15-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Gene3D G3DSA:3.30.930.10 11 460 5.6E-254 T 15-10-2018 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 560 4.8E-243 T 15-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 C2I28_02350 f0e19fb1becb77197ef161b78e796846 565 Gene3D G3DSA:3.40.50.800 4 548 5.6E-254 T 15-10-2018 IPR036621 Anticodon-binding domain superfamily C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 Pfam PF00013 KH domain 212 266 3.4E-6 T 15-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 Gene3D G3DSA:1.10.3210.10 317 472 2.3E-19 T 15-10-2018 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 SMART SM00322 207 274 1.1E-6 T 15-10-2018 IPR004087 K Homology domain GO:0003676 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 SMART SM00471 331 437 3.7E-13 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 SUPERFAMILY SSF54791 207 303 3.42E-16 T 15-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 1.5E-25 T 15-10-2018 IPR006675 HDIG domain C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 Pfam PF12072 Domain of unknown function (DUF3552) 5 204 9.9E-77 T 15-10-2018 IPR022711 Ribonuclease Y, N-terminal C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 Gene3D G3DSA:3.30.1370.10 207 301 1.1E-8 T 15-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 Pfam PF01966 HD domain 336 427 7.7E-19 T 15-10-2018 IPR006674 HD domain C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 25.781 T 15-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 SUPERFAMILY SSF109604 315 466 4.04E-31 T 15-10-2018 C2I28_02155 3b0ecf0b85ecb06ab07ca25339486cc3 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 519 1.5E-246 T 15-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 C2I28_04340 214a4d54e895c0cb820d561f015f5dfa 327 Pfam PF12127 SigmaW regulon antibacterial 10 319 1.6E-164 T 15-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity C2I28_04340 214a4d54e895c0cb820d561f015f5dfa 327 SMART SM00244 42 222 0.0054 T 15-10-2018 IPR001107 Band 7 domain C2I28_04340 214a4d54e895c0cb820d561f015f5dfa 327 Hamap MF_01562 UPF0365 protein . 3 323 49.69 T 15-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity C2I28_17940 916d78480df4f03fe9ab0746f9408115 645 Gene3D G3DSA:3.40.720.10 243 551 1.0E-79 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_17940 916d78480df4f03fe9ab0746f9408115 645 PIRSF PIRSF005091 1 627 1.8E-195 T 15-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I28_17940 916d78480df4f03fe9ab0746f9408115 645 SUPERFAMILY SSF53649 249 641 2.06E-76 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_17940 916d78480df4f03fe9ab0746f9408115 645 Pfam PF00884 Sulfatase 251 540 1.5E-40 T 15-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I28_01905 30ebae80803f85810d5f513154246775 230 Gene3D G3DSA:3.20.20.380 2 230 1.5E-68 T 15-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_01905 30ebae80803f85810d5f513154246775 230 Pfam PF03932 CutC family 1 199 6.5E-56 T 15-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_01905 30ebae80803f85810d5f513154246775 230 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 1 205 25.662 T 15-10-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_01905 30ebae80803f85810d5f513154246775 230 SUPERFAMILY SSF110395 1 212 6.67E-58 T 15-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_21225 48ad2b060a443f836b6c382ccce4a9c9 345 SUPERFAMILY SSF101821 70 182 1.39E-31 T 15-10-2018 C2I28_21225 48ad2b060a443f836b6c382ccce4a9c9 345 Gene3D G3DSA:2.40.30.40 73 167 1.9E-126 T 15-10-2018 IPR023367 Peptidase M42, domain 2 C2I28_21225 48ad2b060a443f836b6c382ccce4a9c9 345 SUPERFAMILY SSF53187 3 340 1.45E-57 T 15-10-2018 C2I28_21225 48ad2b060a443f836b6c382ccce4a9c9 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 333 6.1E-90 T 15-10-2018 IPR008007 Peptidase M42 C2I28_21225 48ad2b060a443f836b6c382ccce4a9c9 345 PIRSF PIRSF001123 1 342 6.1E-43 T 15-10-2018 IPR008007 Peptidase M42 C2I28_21225 48ad2b060a443f836b6c382ccce4a9c9 345 Gene3D G3DSA:3.40.630.10 10 338 1.9E-126 T 15-10-2018 C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 SUPERFAMILY SSF51556 62 360 1.56E-97 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 SUPERFAMILY SSF51338 6 392 1.71E-15 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 Gene3D G3DSA:3.20.20.140 62 360 3.3E-146 T 15-10-2018 C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 PIRSF PIRSF038994 5 393 1.9E-133 T 15-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 6 386 8.3E-115 T 15-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 Pfam PF01979 Amidohydrolase family 59 387 7.0E-30 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_13960 4f9cc7bcfcef7c649f5fc814f6720f53 394 Gene3D G3DSA:2.30.40.10 14 387 3.3E-146 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_25785 c280bac12f0814056c8c77ee05e6dae5 161 Gene3D G3DSA:1.25.40.10 46 154 5.5E-24 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_25785 c280bac12f0814056c8c77ee05e6dae5 161 Pfam PF12688 Tetratrico peptide repeat 39 155 5.5E-11 T 15-10-2018 C2I28_25785 c280bac12f0814056c8c77ee05e6dae5 161 Pfam PF13174 Tetratricopeptide repeat 8 34 0.057 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_25785 c280bac12f0814056c8c77ee05e6dae5 161 SUPERFAMILY SSF48452 6 155 6.5E-20 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 Gene3D G3DSA:1.10.10.60 1 49 3.3E-23 T 15-10-2018 C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 3.2E-17 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 8.5E-58 T 15-10-2018 IPR013570 Transcription regulator YsiA, C-terminal C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 SUPERFAMILY SSF46689 3 82 8.25E-18 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 SUPERFAMILY SSF48498 78 191 1.61E-28 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.2E-11 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.2E-11 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_05220 1d9b668b17fccfdf7d80aa86716675e2 194 Gene3D G3DSA:1.10.357.10 50 193 1.4E-36 T 15-10-2018 C2I28_05415 45a13abe7ac135860a14c5d4ab432b83 369 Pfam PF01594 AI-2E family transporter 13 355 2.0E-59 T 15-10-2018 IPR002549 Transmembrane protein TqsA-like C2I28_05415 45a13abe7ac135860a14c5d4ab432b83 369 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 14 359 6.5E-107 T 15-10-2018 IPR014227 Putative transport protein YtvI-like C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 260 3.6E-16 T 15-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 266 16.165 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 SUPERFAMILY SSF48179 161 262 1.43E-18 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 SUPERFAMILY SSF51735 2 156 9.89E-25 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 Gene3D G3DSA:3.40.50.720 1 161 1.2E-32 T 15-10-2018 C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 PIRSF PIRSF000193 1 265 3.7E-69 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 6.7E-19 T 15-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I28_04445 0c3c3b8107a29459290235dea4a47f34 276 Gene3D G3DSA:1.10.3730.10 162 262 7.9E-15 T 15-10-2018 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.5E-22 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 PRINTS PR01035 Tetracycline resistance protein signature 135 157 1.5E-22 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 PRINTS PR01035 Tetracycline resistance protein signature 163 183 1.5E-22 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 PRINTS PR01035 Tetracycline resistance protein signature 281 302 1.5E-22 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 PRINTS PR01035 Tetracycline resistance protein signature 20 36 1.5E-22 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 Pfam PF07690 Major Facilitator Superfamily 14 230 2.3E-43 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 SUPERFAMILY SSF103473 8 394 6.93E-75 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_18615 62ca9d8ee6f79eaa1edae74c47a63e9e 405 Gene3D G3DSA:1.20.1250.20 3 389 6.4E-75 T 15-10-2018 C2I28_08560 0e76b20773cc8684fe80446b7eab6c01 233 Gene3D G3DSA:3.90.550.10 1 228 1.8E-85 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_08560 0e76b20773cc8684fe80446b7eab6c01 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 222 42.891 T 15-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I28_08560 0e76b20773cc8684fe80446b7eab6c01 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 2.0E-79 T 15-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I28_08560 0e76b20773cc8684fe80446b7eab6c01 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 15-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I28_08560 0e76b20773cc8684fe80446b7eab6c01 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 4.4E-80 T 15-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 C2I28_08560 0e76b20773cc8684fe80446b7eab6c01 233 SUPERFAMILY SSF53448 4 223 1.46E-63 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_26175 69cffc7a5149c319671032858831835c 147 SUPERFAMILY SSF46785 4 59 6.84E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26175 69cffc7a5149c319671032858831835c 147 SMART SM00344 1 105 5.3E-26 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_26175 69cffc7a5149c319671032858831835c 147 Pfam PF01037 Lrp/AsnC ligand binding domain 82 131 1.5E-8 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_26175 69cffc7a5149c319671032858831835c 147 SUPERFAMILY SSF54909 65 133 1.47E-11 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_26175 69cffc7a5149c319671032858831835c 147 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 48 1.4E-14 T 15-10-2018 C2I28_26175 69cffc7a5149c319671032858831835c 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.2E-10 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_26175 69cffc7a5149c319671032858831835c 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.2E-10 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_26175 69cffc7a5149c319671032858831835c 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.2E-10 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_26175 69cffc7a5149c319671032858831835c 147 Gene3D G3DSA:3.30.70.920 52 137 1.5E-16 T 15-10-2018 C2I28_26175 69cffc7a5149c319671032858831835c 147 Gene3D G3DSA:1.10.10.10 3 51 5.1E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00065 69cffc7a5149c319671032858831835c 147 SUPERFAMILY SSF46785 4 59 6.84E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00065 69cffc7a5149c319671032858831835c 147 SMART SM00344 1 105 5.3E-26 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_00065 69cffc7a5149c319671032858831835c 147 Pfam PF01037 Lrp/AsnC ligand binding domain 82 131 1.5E-8 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_00065 69cffc7a5149c319671032858831835c 147 SUPERFAMILY SSF54909 65 133 1.47E-11 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_00065 69cffc7a5149c319671032858831835c 147 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 48 1.4E-14 T 15-10-2018 C2I28_00065 69cffc7a5149c319671032858831835c 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.2E-10 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_00065 69cffc7a5149c319671032858831835c 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.2E-10 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_00065 69cffc7a5149c319671032858831835c 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.2E-10 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_00065 69cffc7a5149c319671032858831835c 147 Gene3D G3DSA:3.30.70.920 52 137 1.5E-16 T 15-10-2018 C2I28_00065 69cffc7a5149c319671032858831835c 147 Gene3D G3DSA:1.10.10.10 3 51 5.1E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17965 135b4ca7e4c8859564aea735b602e715 255 Gene3D G3DSA:3.20.20.370 28 244 6.3E-76 T 15-10-2018 C2I28_17965 135b4ca7e4c8859564aea735b602e715 255 SUPERFAMILY SSF88713 32 236 9.64E-69 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_17965 135b4ca7e4c8859564aea735b602e715 255 Pfam PF01522 Polysaccharide deacetylase 43 162 7.6E-36 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_05835 14c972e216e3b97adfc4da606d36cacb 258 SUPERFAMILY SSF53474 7 254 2.55E-31 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_05835 14c972e216e3b97adfc4da606d36cacb 258 Pfam PF12146 Serine aminopeptidase, S33 8 242 2.4E-52 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_05835 14c972e216e3b97adfc4da606d36cacb 258 Gene3D G3DSA:3.40.50.1820 1 258 1.7E-45 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PIRSF PIRSF006060 8 42 300.0 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PIRSF PIRSF006060 43 264 7.8E-12 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PRINTS PR00175 Sodium/alanine symporter signature 211 230 8.2E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PRINTS PR00175 Sodium/alanine symporter signature 302 320 8.2E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PRINTS PR00175 Sodium/alanine symporter signature 407 427 8.2E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PRINTS PR00175 Sodium/alanine symporter signature 183 201 8.2E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PRINTS PR00175 Sodium/alanine symporter signature 347 369 8.2E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 PRINTS PR00175 Sodium/alanine symporter signature 92 114 8.2E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 Pfam PF01235 Sodium:alanine symporter family 56 450 1.0E-164 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 438 5.9E-161 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01490 5976987811057f2c8694c5ccb5a49bc7 477 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-21 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 SUPERFAMILY SSF46785 1 84 1.96E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 Pfam PF03466 LysR substrate binding domain 89 289 9.8E-40 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 Gene3D G3DSA:3.40.190.290 90 296 1.2E-49 T 15-10-2018 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 SUPERFAMILY SSF53850 89 294 1.28E-39 T 15-10-2018 C2I28_01350 2bdf52cdd89d744118ecc8847d91086f 299 Gene3D G3DSA:1.10.10.10 1 83 1.5E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_10405 0afda5b42abcd89739c2c19cca237238 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 266 2.9E-93 T 15-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I28_10405 0afda5b42abcd89739c2c19cca237238 274 Pfam PF02673 Bacitracin resistance protein BacA 7 268 9.7E-83 T 15-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I28_10405 0afda5b42abcd89739c2c19cca237238 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 273 17.858 T 15-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 C2I28_12205 2d86ffacf1bb8fe84f9e8dc98ffe8884 499 Pfam PF00474 Sodium:solute symporter family 40 433 1.4E-21 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_12205 2d86ffacf1bb8fe84f9e8dc98ffe8884 499 Gene3D G3DSA:1.20.1730.10 25 498 4.1E-36 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 Gene3D G3DSA:1.10.10.10 127 231 1.7E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 Pfam PF00072 Response regulator receiver domain 5 115 2.5E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 SUPERFAMILY SSF52172 3 131 2.42E-41 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 1.0E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 Gene3D G3DSA:3.40.50.2300 1 123 6.9E-38 T 15-10-2018 C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 SUPERFAMILY SSF46894 127 228 1.22E-30 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 SMART SM00448 3 114 6.0E-43 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_00345 91fd45d3dcb17d93097356c4ee4b0508 231 SMART SM00862 153 228 4.7E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_04780 7a7965cb87bf4f7fd9292e7410d9ebb2 359 Pfam PF09557 Domain of unknown function (DUF2382) 143 251 2.1E-26 T 15-10-2018 IPR019060 Domain of unknown function DUF2382 C2I28_04780 7a7965cb87bf4f7fd9292e7410d9ebb2 359 Pfam PF11181 Heat induced stress protein YflT 8 117 4.7E-15 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_04780 7a7965cb87bf4f7fd9292e7410d9ebb2 359 TIGRFAM TIGR02271 TIGR02271: conserved domain 142 255 6.1E-35 T 15-10-2018 IPR019060 Domain of unknown function DUF2382 C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Pfam PF03880 DbpA RNA binding domain 407 477 5.6E-21 T 15-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Gene3D G3DSA:3.30.70.330 406 481 5.4E-29 T 15-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Gene3D G3DSA:3.40.50.300 1 209 1.5E-74 T 15-10-2018 C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 SMART SM00487 23 220 1.7E-58 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Gene3D G3DSA:3.40.50.300 211 380 1.7E-51 T 15-10-2018 C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 6 480 75.809 T 15-10-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 SUPERFAMILY SSF52540 71 358 9.32E-75 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Pfam PF00270 DEAD/DEAH box helicase 28 194 7.5E-48 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 Pfam PF00271 Helicase conserved C-terminal domain 231 337 8.6E-30 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 15-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site C2I28_12000 bf8a94d69d1821a8fc110254dee559a3 481 SMART SM00490 256 337 2.6E-33 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 SUPERFAMILY SSF100950 3 340 4.94E-116 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 1.8E-138 T 15-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 Gene3D G3DSA:1.20.120.420 1 148 4.7E-52 T 15-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 Pfam PF01008 Initiation factor 2 subunit family 49 336 5.6E-88 T 15-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 Gene3D G3DSA:3.40.50.10470 149 351 5.0E-69 T 15-10-2018 C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 336 2.3E-127 T 15-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I28_14280 f4bf47f446af39acfffb2d7af7078347 352 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 38.818 T 15-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Gene3D G3DSA:3.40.50.20 1 93 1.5E-36 T 15-10-2018 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 418 9.9E-168 T 15-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.1E-80 T 15-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Gene3D G3DSA:3.30.1490.20 119 188 1.1E-26 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 15-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 SUPERFAMILY SSF52440 2 101 3.74E-34 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 SUPERFAMILY SSF51246 323 418 3.3E-28 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 SMART SM01210 325 418 5.2E-45 T 15-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 42.867 T 15-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 SUPERFAMILY SSF56059 102 320 1.47E-62 T 15-10-2018 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.6E-34 T 15-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Gene3D G3DSA:3.90.600.10 325 424 4.8E-34 T 15-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Gene3D G3DSA:3.30.470.20 189 324 2.0E-58 T 15-10-2018 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 SMART SM01209 101 293 1.9E-130 T 15-10-2018 C2I28_09480 78fe2019524c11dd5039627fe421ebec 424 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 326 416 8.4E-27 T 15-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 C2I28_19640 202e9b90c8ddb8c3aa1a1a1fad81116c 197 SMART SM00479 8 175 9.6E-15 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_19640 202e9b90c8ddb8c3aa1a1a1fad81116c 197 Pfam PF00929 Exonuclease 11 165 8.9E-18 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_19640 202e9b90c8ddb8c3aa1a1a1fad81116c 197 Gene3D G3DSA:3.30.420.10 5 173 7.4E-33 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_19640 202e9b90c8ddb8c3aa1a1a1fad81116c 197 SUPERFAMILY SSF53098 10 172 9.11E-38 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 SUPERFAMILY SSF46977 410 502 2.09E-20 T 15-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 Gene3D G3DSA:3.90.700.10 230 335 3.3E-141 T 15-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 SUPERFAMILY SSF56425 220 329 1.41E-30 T 15-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 354 4.4E-9 T 15-10-2018 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.4E-9 T 15-10-2018 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 Pfam PF00890 FAD binding domain 5 369 4.2E-86 T 15-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 Pfam PF02910 Fumarate reductase flavoprotein C-term 411 508 1.3E-11 T 15-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 489 1.2E-155 T 15-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 Gene3D G3DSA:1.20.58.100 403 505 2.7E-19 T 15-10-2018 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 PIRSF PIRSF000171 1 443 1.8E-30 T 15-10-2018 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 PIRSF PIRSF000171 449 513 0.0052 T 15-10-2018 C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 SUPERFAMILY SSF51905 2 406 6.85E-63 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_04810 a905a36e35c84fb38ab8d33b708cc233 514 Gene3D G3DSA:3.50.50.60 5 381 3.3E-141 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03710 af3e6c753881f6924a54f0932b80eb06 316 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 147 311 5.6E-55 T 15-10-2018 IPR021062 Putative aromatic acid exporter, C-terminal C2I28_03710 af3e6c753881f6924a54f0932b80eb06 316 Gene3D G3DSA:1.20.120.940 142 315 1.1E-53 T 15-10-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily C2I28_03710 af3e6c753881f6924a54f0932b80eb06 316 Pfam PF06081 Aromatic acid exporter family member 1 3 143 9.8E-52 T 15-10-2018 IPR010343 Aromatic acid exporter family member 1 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00690 Adhesin family signature 67 80 3.0E-11 T 15-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00690 Adhesin family signature 80 97 3.0E-11 T 15-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00690 Adhesin family signature 204 225 3.0E-11 T 15-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00690 Adhesin family signature 36 54 3.0E-11 T 15-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 Gene3D G3DSA:3.40.50.1980 208 319 2.2E-38 T 15-10-2018 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 SUPERFAMILY SSF53807 35 318 3.29E-81 T 15-10-2018 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 317 6.0E-71 T 15-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00691 Adhesin B signature 61 79 1.8E-10 T 15-10-2018 IPR006129 Adhesin B GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00691 Adhesin B signature 297 315 1.8E-10 T 15-10-2018 IPR006129 Adhesin B GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00691 Adhesin B signature 36 57 1.8E-10 T 15-10-2018 IPR006129 Adhesin B GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 PRINTS PR00691 Adhesin B signature 80 99 1.8E-10 T 15-10-2018 IPR006129 Adhesin B GO:0007155 C2I28_05930 4a0ffc998a13e222d5cbf44ce0ea5228 319 Gene3D G3DSA:3.40.50.1980 25 205 4.5E-58 T 15-10-2018 C2I28_10965 36b54bfb2f8791352e8acffdf630399d 69 PIRSF PIRSF037692 1 69 3.8E-26 T 15-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 C2I28_10965 36b54bfb2f8791352e8acffdf630399d 69 ProDom PD056348 YHEE BH1143 1 69 2.0E-15 T 15-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 C2I28_10965 36b54bfb2f8791352e8acffdf630399d 69 Pfam PF17277 Family of unknown function (DUF5342) 1 69 1.6E-30 T 15-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 C2I28_08830 8a88bb3de2b6bcfe93114b99e2e43319 279 SMART SM00382 32 217 3.8E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08830 8a88bb3de2b6bcfe93114b99e2e43319 279 Gene3D G3DSA:3.40.50.300 2 277 3.5E-76 T 15-10-2018 C2I28_08830 8a88bb3de2b6bcfe93114b99e2e43319 279 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_08830 8a88bb3de2b6bcfe93114b99e2e43319 279 Pfam PF00005 ABC transporter 23 169 2.3E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_08830 8a88bb3de2b6bcfe93114b99e2e43319 279 SUPERFAMILY SSF52540 6 229 5.08E-65 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08830 8a88bb3de2b6bcfe93114b99e2e43319 279 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 273 4.2E-116 T 15-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 C2I28_10580 f36fce898a919c7c3ca68fa6cfd87564 444 SUPERFAMILY SSF53474 194 389 7.71E-23 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10580 f36fce898a919c7c3ca68fa6cfd87564 444 Gene3D G3DSA:2.60.40.2180 33 180 8.0E-16 T 15-10-2018 C2I28_10580 f36fce898a919c7c3ca68fa6cfd87564 444 Gene3D G3DSA:3.40.50.1820 189 440 1.6E-47 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10580 f36fce898a919c7c3ca68fa6cfd87564 444 Pfam PF00326 Prolyl oligopeptidase family 282 329 3.9E-8 T 15-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 C2I28_10575 f3ad58b7aa8a2f923f880b8c5a7dbfd0 69 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 5.9E-22 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_10575 f3ad58b7aa8a2f923f880b8c5a7dbfd0 69 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_10575 f3ad58b7aa8a2f923f880b8c5a7dbfd0 69 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_10575 f3ad58b7aa8a2f923f880b8c5a7dbfd0 69 Gene3D G3DSA:1.10.8.910 10 68 7.3E-31 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 Gene3D G3DSA:3.60.20.40 343 516 8.1E-56 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 Pfam PF01019 Gamma-glutamyltranspeptidase 48 513 8.3E-111 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 393 408 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 417 434 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 343 361 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 247 266 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 55 80 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 109 127 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 127 146 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 218 234 1.7E-49 T 15-10-2018 C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 SUPERFAMILY SSF56235 23 514 1.05E-127 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_13145 049ea92ff2e3e823ba17e3c2f1722ef9 520 Gene3D G3DSA:1.10.246.230 234 335 5.3E-26 T 15-10-2018 C2I28_17625 7d2f6a192d430d50e193256d8d77225a 107 Pfam PF01638 HxlR-like helix-turn-helix 16 104 2.1E-29 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_17625 7d2f6a192d430d50e193256d8d77225a 107 SUPERFAMILY SSF46785 7 102 1.79E-27 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_17625 7d2f6a192d430d50e193256d8d77225a 107 Gene3D G3DSA:1.10.10.10 5 107 4.4E-32 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 532 542 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 226 239 3.5E-21 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 196 3.5E-21 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 PRINTS PR00723 Subtilisin serine protease family (S8) signature 531 547 3.5E-21 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 Pfam PF02225 PA domain 388 461 4.6E-15 T 15-10-2018 IPR003137 PA domain C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 Gene3D G3DSA:3.30.70.80 49 138 9.5E-6 T 15-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 SUPERFAMILY SSF52025 353 470 3.14E-21 T 15-10-2018 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 Pfam PF00082 Subtilase family 177 586 3.2E-75 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 Gene3D G3DSA:3.50.30.30 353 476 8.5E-31 T 15-10-2018 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 182 193 - T 15-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 SUPERFAMILY SSF52743 78 607 2.88E-83 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 Pfam PF05922 Peptidase inhibitor I9 57 141 1.1E-8 T 15-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 Gene3D G3DSA:2.60.40.4070 718 796 4.1E-6 T 15-10-2018 C2I28_19055 aaa7d2765bd3eaac894451240b22ebe2 803 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 230 240 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_00505 c739c6f9657e3f63fcd485fa4cf4ef15 193 Pfam PF02659 Putative manganese efflux pump 3 82 1.2E-8 T 15-10-2018 IPR003810 Putative manganese efflux pump C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 SUPERFAMILY SSF52540 256 489 1.81E-43 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 SUPERFAMILY SSF52540 3 227 2.04E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 SMART SM00382 29 218 2.7E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 Pfam PF00005 ABC transporter 275 429 1.4E-17 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 Pfam PF00005 ABC transporter 21 169 1.3E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 Gene3D G3DSA:3.40.50.300 1 236 4.9E-56 T 15-10-2018 C2I28_02215 1892167d99a67ef3c489d6ee7f0233c3 509 Gene3D G3DSA:3.40.50.300 252 494 5.8E-41 T 15-10-2018 C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 Gene3D G3DSA:1.10.1040.10 190 285 1.6E-32 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 2.0E-32 T 15-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 PIRSF PIRSF000105 1 285 1.3E-88 T 15-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 SUPERFAMILY SSF51735 2 185 1.19E-53 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 3.4E-60 T 15-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 SUPERFAMILY SSF48179 185 284 8.5E-33 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_17235 78edf420c41ad200f8047fcedaf0953f 285 Gene3D G3DSA:3.40.50.720 1 189 7.0E-63 T 15-10-2018 C2I28_24280 36e2f07d166b9fabdd3d1923576e40f5 186 Gene3D G3DSA:3.40.50.300 3 186 2.9E-21 T 15-10-2018 C2I28_24280 36e2f07d166b9fabdd3d1923576e40f5 186 SUPERFAMILY SSF52540 1 184 1.11E-13 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_24280 36e2f07d166b9fabdd3d1923576e40f5 186 Pfam PF01202 Shikimate kinase 13 183 3.6E-5 T 15-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 C2I28_15125 d94b78d2acf9c1b29b843dcecda3f305 219 Gene3D G3DSA:3.30.110.170 25 217 1.3E-46 T 15-10-2018 C2I28_15125 d94b78d2acf9c1b29b843dcecda3f305 219 Pfam PF04402 Protein of unknown function (DUF541) 23 217 7.1E-38 T 15-10-2018 IPR007497 Protein of unknown function DUF541 C2I28_15125 d94b78d2acf9c1b29b843dcecda3f305 219 Gene3D G3DSA:3.30.70.2970 35 141 1.3E-46 T 15-10-2018 C2I28_06275 52c0e8d46dc3393aa7205fa806787a77 120 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 107 8.0E-30 T 15-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 C2I28_06275 52c0e8d46dc3393aa7205fa806787a77 120 Pfam PF03334 Na+/H+ antiporter subunit 12 93 2.4E-27 T 15-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 C2I28_22090 73b6ede53283fa59a00a7b5f9ae3a569 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 15-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I28_22090 73b6ede53283fa59a00a7b5f9ae3a569 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 98 2.9E-17 T 15-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I28_22090 73b6ede53283fa59a00a7b5f9ae3a569 132 SUPERFAMILY SSF53927 2 130 4.35E-50 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_22090 73b6ede53283fa59a00a7b5f9ae3a569 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 2.2E-45 T 15-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 C2I28_22090 73b6ede53283fa59a00a7b5f9ae3a569 132 Gene3D G3DSA:3.40.140.10 1 132 1.8E-58 T 15-10-2018 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 2.5E-29 T 15-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 2.5E-29 T 15-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 2.5E-29 T 15-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 65 84 2.5E-29 T 15-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 Pfam PF00579 tRNA synthetases class I (W and Y) 4 281 3.0E-84 T 15-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 Gene3D G3DSA:3.40.50.620 5 324 5.7E-141 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 SUPERFAMILY SSF52374 3 325 2.9E-100 T 15-10-2018 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 325 1.5E-123 T 15-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 326 42.504 T 15-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 C2I28_11690 c8e168d262ee0cc3275fb3f45c38157d 329 Gene3D G3DSA:1.10.240.10 184 294 5.7E-141 T 15-10-2018 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 43.534 T 15-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 SUPERFAMILY SSF53720 3 414 9.56E-125 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 Gene3D G3DSA:3.40.605.10 18 409 1.2E-172 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 8.0E-158 T 15-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 Pfam PF00171 Aldehyde dehydrogenase family 300 404 4.1E-6 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 Pfam PF00171 Aldehyde dehydrogenase family 9 284 6.3E-17 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 PIRSF PIRSF000151 1 414 4.4E-188 T 15-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 Gene3D G3DSA:3.40.309.10 224 372 1.2E-172 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_07760 003b40a1dc4d12b9b2429bf03b331d93 414 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 342 - T 15-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_25745 3d9d614cd2dd8ea7910aa43decddcbe4 297 Gene3D G3DSA:3.90.850.10 73 295 1.9E-70 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_25745 3d9d614cd2dd8ea7910aa43decddcbe4 297 SUPERFAMILY SSF56529 69 289 4.97E-34 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_25745 3d9d614cd2dd8ea7910aa43decddcbe4 297 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 289 2.6E-22 T 15-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 C2I28_26490 11d45c57bf251314dcb68b51c47c6dcd 79 SUPERFAMILY SSF47336 4 72 6.33E-7 T 15-10-2018 IPR036736 ACP-like superfamily C2I28_26490 11d45c57bf251314dcb68b51c47c6dcd 79 Gene3D G3DSA:1.10.1200.10 1 72 1.8E-10 T 15-10-2018 IPR036736 ACP-like superfamily C2I28_12500 54598bde2f795457ad0dac19e5b80beb 495 Pfam PF00171 Aldehyde dehydrogenase family 19 481 1.6E-184 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_12500 54598bde2f795457ad0dac19e5b80beb 495 PIRSF PIRSF036492 25 489 1.5E-86 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_12500 54598bde2f795457ad0dac19e5b80beb 495 SUPERFAMILY SSF53720 8 484 3.4E-177 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_12500 54598bde2f795457ad0dac19e5b80beb 495 Gene3D G3DSA:3.40.309.10 258 451 2.0E-191 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_12500 54598bde2f795457ad0dac19e5b80beb 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_12500 54598bde2f795457ad0dac19e5b80beb 495 Gene3D G3DSA:3.40.605.10 22 475 2.0E-191 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 SUPERFAMILY SSF160544 250 357 8.37E-41 T 15-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 Gene3D G3DSA:3.40.1690.10 224 360 2.7E-56 T 15-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 308 329 3.8E-40 T 15-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 234 251 3.8E-40 T 15-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 16 38 3.8E-40 T 15-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 214 232 3.8E-40 T 15-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 278 293 3.8E-40 T 15-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 14 359 8.9E-130 T 15-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 C2I28_02440 f26f2852b019d29221b134cd7fb2a0b1 360 Pfam PF01312 FlhB HrpN YscU SpaS Family 13 353 7.8E-130 T 15-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 C2I28_18515 b331b6ef4fb911c66367a66d9f2963c8 410 Gene3D G3DSA:1.10.1660.10 2 73 8.6E-12 T 15-10-2018 C2I28_18515 b331b6ef4fb911c66367a66d9f2963c8 410 Pfam PF13411 MerR HTH family regulatory protein 5 72 1.7E-12 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_18515 b331b6ef4fb911c66367a66d9f2963c8 410 SUPERFAMILY SSF46955 5 83 1.69E-10 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_18515 b331b6ef4fb911c66367a66d9f2963c8 410 SMART SM00422 5 74 0.0021 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_01045 8777dd2b5ff48f54b580e5aa7158e38d 371 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 363 1.6E-72 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_01045 8777dd2b5ff48f54b580e5aa7158e38d 371 Pfam PF03845 Spore germination protein 5 325 6.0E-85 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_02485 769c2aeb8e77e6bad1bf2832c8cdbbe4 69 Pfam PF06289 Flagellar protein (FlbD) 1 58 4.6E-27 T 15-10-2018 IPR009384 Swarming motility protein SwrD-like C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PIRSF PIRSF038928 1 482 2.4E-227 T 15-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PRINTS PR00067 Catalase signature 85 103 2.2E-78 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PRINTS PR00067 Catalase signature 322 348 2.2E-78 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PRINTS PR00067 Catalase signature 290 317 2.2E-78 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PRINTS PR00067 Catalase signature 106 123 2.2E-78 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PRINTS PR00067 Catalase signature 125 143 2.2E-78 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 PRINTS PR00067 Catalase signature 22 45 2.2E-78 T 15-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 SUPERFAMILY SSF56634 3 483 1.1E-220 T 15-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 SMART SM01060 9 393 4.3E-298 T 15-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 Pfam PF00199 Catalase 9 390 1.8E-199 T 15-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 ProSitePatterns PS00438 Catalase proximal active site signature. 45 61 - T 15-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 Gene3D G3DSA:2.40.180.10 1 484 5.6E-235 T 15-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 Pfam PF06628 Catalase-related immune-responsive 415 477 4.3E-26 T 15-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_07775 3832ee4a1b87a05d255f56d1ea604804 486 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 335 343 - T 15-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 C2I28_09600 d6f0c125c9a68069d10664a7b4121185 337 SUPERFAMILY SSF51412 5 336 2.75E-59 T 15-10-2018 C2I28_09600 d6f0c125c9a68069d10664a7b4121185 337 Pfam PF03060 Nitronate monooxygenase 7 334 4.4E-90 T 15-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 C2I28_09600 d6f0c125c9a68069d10664a7b4121185 337 Gene3D G3DSA:3.20.20.70 1 337 1.1E-106 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 32 96 2.4E-12 T 15-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 Gene3D G3DSA:3.30.1330.30 2 97 2.5E-25 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 Gene3D G3DSA:3.40.1280.10 98 251 4.2E-53 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 SMART SM00967 31 100 8.4E-13 T 15-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 SUPERFAMILY SSF55315 2 96 1.65E-24 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 SUPERFAMILY SSF75217 93 249 1.96E-42 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_05275 c9a04f90809fa1f3f822f5e6ac0ae8be 252 Pfam PF00588 SpoU rRNA Methylase family 109 247 4.6E-38 T 15-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I28_17330 3f7cb604cd21aa30a328cce97cc0eeb3 300 Pfam PF02628 Cytochrome oxidase assembly protein 51 287 3.1E-33 T 15-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 Pfam PF00202 Aminotransferase class-III 26 424 1.6E-123 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 Gene3D G3DSA:3.40.640.10 62 326 1.7E-152 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 Gene3D G3DSA:3.90.1150.10 8 422 1.7E-152 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 PIRSF PIRSF000521 11 130 9.2E-6 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 PIRSF PIRSF000521 123 427 1.6E-42 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 SUPERFAMILY SSF53383 24 426 1.07E-130 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_19925 cd4117cbc58543600df84cfea85b7ddb 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_10395 bcc6617cf7150a11c41967088fdc9e8d 589 Pfam PF01964 Radical SAM ThiC family 132 552 6.7E-205 T 15-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I28_10395 bcc6617cf7150a11c41967088fdc9e8d 589 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 131 555 6.2E-224 T 15-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I28_10395 bcc6617cf7150a11c41967088fdc9e8d 589 Gene3D G3DSA:3.20.20.540 175 488 1.1E-155 T 15-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I28_10395 bcc6617cf7150a11c41967088fdc9e8d 589 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 131 557 99.483 T 15-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I28_10395 bcc6617cf7150a11c41967088fdc9e8d 589 Pfam PF13667 ThiC-associated domain 13 90 1.8E-34 T 15-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 Hamap MF_01685 Ferredoxin--NADP reductase. 7 328 44.198 T 15-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 Gene3D G3DSA:3.50.50.60 7 304 6.3E-117 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 1.0E-18 T 15-10-2018 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.0E-18 T 15-10-2018 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.0E-18 T 15-10-2018 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.0E-18 T 15-10-2018 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 Gene3D G3DSA:3.50.50.60 128 246 6.3E-117 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.1E-24 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 1.1E-24 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.1E-24 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 1.1E-24 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 1.1E-24 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 1.1E-24 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 SUPERFAMILY SSF51905 8 315 2.72E-42 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06385 e415e5e468e48ef06bca40a4c2ff104b 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 302 3.5E-31 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_12820 aeafc938230e36476cb4148293c8f293 306 Pfam PF13407 Periplasmic binding protein domain 40 290 2.0E-64 T 15-10-2018 IPR025997 Periplasmic binding protein C2I28_12820 aeafc938230e36476cb4148293c8f293 306 Gene3D G3DSA:3.40.50.2300 138 271 2.0E-90 T 15-10-2018 C2I28_12820 aeafc938230e36476cb4148293c8f293 306 SUPERFAMILY SSF53822 30 305 2.51E-89 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_12820 aeafc938230e36476cb4148293c8f293 306 Gene3D G3DSA:3.40.50.2300 44 290 2.0E-90 T 15-10-2018 C2I28_16775 4d61fb4edb1b5810b686104d423f5f98 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 131 283 1.6E-14 T 15-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I28_16775 4d61fb4edb1b5810b686104d423f5f98 303 SUPERFAMILY SSF48150 115 298 3.31E-34 T 15-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 C2I28_16775 4d61fb4edb1b5810b686104d423f5f98 303 Gene3D G3DSA:1.10.340.30 123 246 2.0E-43 T 15-10-2018 C2I28_16775 4d61fb4edb1b5810b686104d423f5f98 303 Gene3D G3DSA:1.10.1670.40 104 295 2.0E-43 T 15-10-2018 C2I28_16775 4d61fb4edb1b5810b686104d423f5f98 303 SMART SM00478 135 299 1.0E-4 T 15-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 C2I28_08500 8120cf502532ded9b06a1115969149d9 181 SUPERFAMILY SSF55083 4 154 5.36E-53 T 15-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I28_08500 8120cf502532ded9b06a1115969149d9 181 Gene3D G3DSA:3.30.70.560 2 180 2.8E-57 T 15-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I28_08500 8120cf502532ded9b06a1115969149d9 181 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 7.4E-46 T 15-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I28_08500 8120cf502532ded9b06a1115969149d9 181 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 1.2E-38 T 15-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 C2I28_04535 6068f9fa4376b760c56888dc7df2ec64 213 Gene3D G3DSA:3.40.50.150 24 213 1.5E-40 T 15-10-2018 C2I28_04535 6068f9fa4376b760c56888dc7df2ec64 213 Hamap MF_02100 Uncharacterized methyltransferase . 2 213 43.311 T 15-10-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 C2I28_04535 6068f9fa4376b760c56888dc7df2ec64 213 Pfam PF13649 Methyltransferase domain 49 140 2.2E-9 T 15-10-2018 C2I28_04535 6068f9fa4376b760c56888dc7df2ec64 213 SUPERFAMILY SSF53335 7 200 3.34E-24 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_24890 18f0a1a2b28291518ab2a646019e201b 298 SUPERFAMILY SSF53474 14 289 6.35E-45 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_24890 18f0a1a2b28291518ab2a646019e201b 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.6E-5 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_24890 18f0a1a2b28291518ab2a646019e201b 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.6E-5 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_24890 18f0a1a2b28291518ab2a646019e201b 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.6E-5 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_24890 18f0a1a2b28291518ab2a646019e201b 298 Pfam PF00561 alpha/beta hydrolase fold 30 283 7.0E-22 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_24890 18f0a1a2b28291518ab2a646019e201b 298 Gene3D G3DSA:3.40.50.1820 13 290 5.6E-45 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10150 380123c335d08952b68bdf59b613f756 130 Pfam PF07885 Ion channel 44 127 1.6E-10 T 15-10-2018 IPR013099 Potassium channel domain C2I28_10150 380123c335d08952b68bdf59b613f756 130 SUPERFAMILY SSF81324 35 126 1.96E-13 T 15-10-2018 C2I28_10150 380123c335d08952b68bdf59b613f756 130 Gene3D G3DSA:1.10.287.70 26 130 1.2E-12 T 15-10-2018 C2I28_07505 4c3a646ebc1f17aa43d227b2e83c9a21 703 SUPERFAMILY SSF103501 7 238 3.53E-18 T 15-10-2018 IPR036197 NarG-like superfamily C2I28_07505 4c3a646ebc1f17aa43d227b2e83c9a21 703 SUPERFAMILY SSF46548 253 399 5.41E-19 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_07505 4c3a646ebc1f17aa43d227b2e83c9a21 703 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_07505 4c3a646ebc1f17aa43d227b2e83c9a21 703 Pfam PF02754 Cysteine-rich domain 459 537 2.2E-5 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_07505 4c3a646ebc1f17aa43d227b2e83c9a21 703 Pfam PF02754 Cysteine-rich domain 581 668 6.0E-18 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_07505 4c3a646ebc1f17aa43d227b2e83c9a21 703 Pfam PF13183 4Fe-4S dicluster domain 274 383 3.7E-12 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 SMART SM00839 144 351 9.9E-72 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 346 1.0E-10 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 2.2E-6 T 15-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 19 131 6.0E-27 T 15-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 SUPERFAMILY SSF53223 4 143 9.6E-49 T 15-10-2018 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 Gene3D G3DSA:3.40.50.10860 10 343 1.3E-153 T 15-10-2018 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 15-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 PIRSF PIRSF000188 1 353 8.3E-167 T 15-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 SUPERFAMILY SSF51735 141 348 1.8E-58 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 Gene3D G3DSA:3.40.50.720 134 336 1.3E-153 T 15-10-2018 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.1E-22 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.1E-22 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.1E-22 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_03775 3837e61ab4aecc11ad7c063c97d44aab 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.1E-22 T 15-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 C2I28_17925 62626e703607f9ade5dfebde12c2e681 367 SUPERFAMILY SSF53448 29 247 1.01E-29 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_17925 62626e703607f9ade5dfebde12c2e681 367 Pfam PF00535 Glycosyl transferase family 2 35 165 4.2E-23 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_17925 62626e703607f9ade5dfebde12c2e681 367 Gene3D G3DSA:3.90.550.10 26 223 1.5E-31 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_02990 375059cdafb964b6351456b710a2a2da 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 3.6E-127 T 15-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I28_02990 375059cdafb964b6351456b710a2a2da 311 Gene3D G3DSA:3.40.50.150 4 308 1.8E-105 T 15-10-2018 C2I28_02990 375059cdafb964b6351456b710a2a2da 311 Pfam PF01795 MraW methylase family 2 309 2.2E-134 T 15-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I28_02990 375059cdafb964b6351456b710a2a2da 311 Gene3D G3DSA:1.10.150.170 111 215 1.8E-105 T 15-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 C2I28_02990 375059cdafb964b6351456b710a2a2da 311 SUPERFAMILY SSF53335 3 310 3.78E-46 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_02990 375059cdafb964b6351456b710a2a2da 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 38.922 T 15-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I28_02990 375059cdafb964b6351456b710a2a2da 311 SUPERFAMILY SSF81799 113 214 7.85E-36 T 15-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 C2I28_02990 375059cdafb964b6351456b710a2a2da 311 PIRSF PIRSF004486 1 311 8.4E-111 T 15-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00385 P450 superfamily signature 342 351 2.5E-6 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00385 P450 superfamily signature 276 287 2.5E-6 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00385 P450 superfamily signature 351 362 2.5E-6 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00385 P450 superfamily signature 241 258 2.5E-6 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 351 362 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 195 217 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 293 320 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 321 336 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 86 97 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 149 164 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 132 148 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 342 351 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 PRINTS PR00359 B-class P450 signature 276 287 2.6E-52 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 SUPERFAMILY SSF48264 29 400 6.02E-94 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 Gene3D G3DSA:1.10.630.10 2 403 1.4E-122 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 Pfam PF00067 Cytochrome P450 53 399 2.5E-35 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_18205 feb831b3c89e200b5f818ecaab463be3 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 15-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 C2I28_04175 64560c55530e1a19c0740bc73a16fa26 403 Pfam PF07690 Major Facilitator Superfamily 15 356 1.3E-44 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_04175 64560c55530e1a19c0740bc73a16fa26 403 SUPERFAMILY SSF103473 5 386 4.58E-51 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_04175 64560c55530e1a19c0740bc73a16fa26 403 Gene3D G3DSA:1.20.1250.20 2 389 1.6E-54 T 15-10-2018 C2I28_04175 64560c55530e1a19c0740bc73a16fa26 403 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 76 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_07335 0b0d7a7e8687398982b9a8b120e9170a 172 Pfam PF00430 ATP synthase B/B' CF(0) 19 149 1.5E-35 T 15-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 C2I28_07335 0b0d7a7e8687398982b9a8b120e9170a 172 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 22 168 1.1E-42 T 15-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 C2I28_07335 0b0d7a7e8687398982b9a8b120e9170a 172 Hamap MF_01398 ATP synthase subunit b [atpF]. 13 150 13.984 T 15-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 C2I28_07335 0b0d7a7e8687398982b9a8b120e9170a 172 SUPERFAMILY SSF81573 75 133 6.41E-8 T 15-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily C2I28_12195 c9b24ad76e6401ec9232951afb34d796 329 Gene3D G3DSA:1.10.1500.10 73 210 4.4E-118 T 15-10-2018 C2I28_12195 c9b24ad76e6401ec9232951afb34d796 329 Hamap MF_00313 Glutaminase [glsA]. 16 329 43.913 T 15-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I28_12195 c9b24ad76e6401ec9232951afb34d796 329 Pfam PF04960 Glutaminase 34 329 1.2E-106 T 15-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I28_12195 c9b24ad76e6401ec9232951afb34d796 329 TIGRFAM TIGR03814 Gln_ase: glutaminase A 20 329 6.8E-119 T 15-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 C2I28_12195 c9b24ad76e6401ec9232951afb34d796 329 SUPERFAMILY SSF56601 17 329 4.6E-117 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_12195 c9b24ad76e6401ec9232951afb34d796 329 Gene3D G3DSA:3.40.710.10 47 329 4.4E-118 T 15-10-2018 C2I28_04870 00ed58838bd1603752873c2186baa484 260 Gene3D G3DSA:2.70.70.10 128 258 3.8E-22 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_04870 00ed58838bd1603752873c2186baa484 260 SUPERFAMILY SSF51261 98 256 2.35E-19 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_04870 00ed58838bd1603752873c2186baa484 260 Pfam PF01551 Peptidase family M23 159 253 3.9E-18 T 15-10-2018 IPR016047 Peptidase M23 C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 284 1.5E-92 T 15-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 Gene3D G3DSA:1.10.40.50 227 293 1.4E-22 T 15-10-2018 C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 Gene3D G3DSA:2.40.50.140 1 61 9.6E-27 T 15-10-2018 C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 Pfam PF03193 RsgA GTPase 59 225 1.7E-63 T 15-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 SUPERFAMILY SSF52540 64 291 7.58E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 SUPERFAMILY SSF50249 1 63 2.23E-15 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 Pfam PF16745 RsgA N-terminal domain 3 56 7.8E-25 T 15-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 Gene3D G3DSA:3.40.50.300 62 225 1.0E-48 T 15-10-2018 C2I28_02740 1ef4177fe5a539dc6b207b112f18b315 293 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 290 39.851 T 15-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Gene3D G3DSA:2.170.120.40 232 318 6.9E-18 T 15-10-2018 C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Gene3D G3DSA:2.170.120.40 144 230 1.2E-10 T 15-10-2018 C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Gene3D G3DSA:2.170.120.30 41 143 9.7E-24 T 15-10-2018 C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Gene3D G3DSA:2.170.120.30 328 429 6.2E-17 T 15-10-2018 C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Pfam PF07949 YbbR-like protein 55 135 5.8E-9 T 15-10-2018 IPR012505 YbbR-like C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Pfam PF07949 YbbR-like protein 145 227 6.7E-15 T 15-10-2018 IPR012505 YbbR-like C2I28_08985 1893299408c66d9dd8c2ada7e5e02cc2 518 Pfam PF07949 YbbR-like protein 236 315 4.6E-13 T 15-10-2018 IPR012505 YbbR-like C2I28_13885 7bf94ce946369daf33b7b82fa0b31934 152 SUPERFAMILY SSF54593 1 128 2.06E-20 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_13885 7bf94ce946369daf33b7b82fa0b31934 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 123 1.6E-10 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_13885 7bf94ce946369daf33b7b82fa0b31934 152 Gene3D G3DSA:3.10.180.10 2 125 4.8E-27 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 SUPERFAMILY SSF53383 28 394 1.5E-119 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 Gene3D G3DSA:3.90.1150.10 261 395 3.2E-50 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 PIRSF PIRSF001434 1 395 8.7E-148 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 392 9.8E-145 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 8 394 4.4E-191 T 15-10-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 Gene3D G3DSA:3.40.640.10 4 258 8.3E-94 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_15655 4d3c1621aabd84dd0fe98e230e618c23 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_18905 d270fe1ffa4a6774204b8aaa21788cee 416 SUPERFAMILY SSF53756 7 394 5.38E-48 T 15-10-2018 C2I28_18905 d270fe1ffa4a6774204b8aaa21788cee 416 Gene3D G3DSA:3.40.50.2000 222 382 6.6E-32 T 15-10-2018 C2I28_18905 d270fe1ffa4a6774204b8aaa21788cee 416 Pfam PF00534 Glycosyl transferases group 1 222 377 2.0E-27 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 SUPERFAMILY SSF46689 4 77 1.16E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 Gene3D G3DSA:1.10.357.10 49 189 1.2E-18 T 15-10-2018 C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.1E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.1E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 SUPERFAMILY SSF48498 84 188 4.38E-11 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 Gene3D G3DSA:1.10.10.60 2 48 9.9E-16 T 15-10-2018 C2I28_11170 7b73e616fa4454be7ff4fa16f368d7a3 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 5.5E-16 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_13825 a27dabfec4b764937b00436c5aee17fb 479 Gene3D G3DSA:3.40.980.20 295 478 5.1E-12 T 15-10-2018 C2I28_13825 a27dabfec4b764937b00436c5aee17fb 479 Gene3D G3DSA:3.40.50.10840 48 283 6.0E-10 T 15-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily C2I28_13825 a27dabfec4b764937b00436c5aee17fb 479 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 306 470 1.0E-37 T 15-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain C2I28_13825 a27dabfec4b764937b00436c5aee17fb 479 Pfam PF07005 Putative sugar-binding N-terminal domain 40 281 1.4E-52 T 15-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain C2I28_13825 a27dabfec4b764937b00436c5aee17fb 479 SUPERFAMILY SSF142764 40 477 1.03E-65 T 15-10-2018 C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 Gene3D G3DSA:1.10.10.1230 86 203 1.0E-213 T 15-10-2018 C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 SUPERFAMILY SSF56601 279 696 3.76E-68 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 Gene3D G3DSA:3.40.710.10 327 668 1.0E-213 T 15-10-2018 C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 311 9.8E-35 T 15-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 SUPERFAMILY SSF56519 56 326 9.81E-32 T 15-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 Gene3D G3DSA:3.90.1310.30 61 582 1.0E-213 T 15-10-2018 C2I28_11175 3b6ae01f18c5a519af7856a6d535d234 725 Pfam PF00905 Penicillin binding protein transpeptidase domain 358 687 4.8E-68 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 SUPERFAMILY SSF52788 1 150 1.23E-48 T 15-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 147 4.3E-40 T 15-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 Gene3D G3DSA:3.40.50.2300 1 155 1.4E-61 T 15-10-2018 C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 2.2E-14 T 15-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.2E-14 T 15-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 2.2E-14 T 15-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 2.2E-14 T 15-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 C2I28_09930 40847ba26f8c9258ed88c96c63aed216 157 SMART SM00226 2 149 1.6E-52 T 15-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I28_15355 ece3b9327f2810973ae3c4c68388460b 90 ProDom PD062992 CYTOSOLIC YPZA BH2151 14 89 1.0E-13 T 15-10-2018 IPR020314 Uncharacterised protein family YpzA C2I28_15355 ece3b9327f2810973ae3c4c68388460b 90 Pfam PF10819 Protein of unknown function (DUF2564) 12 89 2.9E-36 T 15-10-2018 IPR020314 Uncharacterised protein family YpzA C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 SMART SM00420 6 58 5.3E-12 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.9E-6 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.9E-6 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 Pfam PF00455 DeoR C terminal sensor domain 72 226 3.2E-44 T 15-10-2018 IPR014036 DeoR C-terminal sensor domain C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 SUPERFAMILY SSF46785 4 60 2.32E-11 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 15-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 SMART SM01134 69 228 1.3E-51 T 15-10-2018 C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.0E-15 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_21565 c8d1dff085a385db6cb85bf432de4d4a 256 SUPERFAMILY SSF100950 72 228 7.12E-28 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_09150 45b4f84114fc6518ac600b1129827e78 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 110 2.4E-33 T 15-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 C2I28_09150 45b4f84114fc6518ac600b1129827e78 116 Gene3D G3DSA:2.30.30.110 1 116 1.0E-52 T 15-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor C2I28_09150 45b4f84114fc6518ac600b1129827e78 116 SUPERFAMILY SSF50118 2 113 1.13E-41 T 15-10-2018 C2I28_09150 45b4f84114fc6518ac600b1129827e78 116 PIRSF PIRSF033490 1 113 4.0E-39 T 15-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 C2I28_25360 3911c8e2494de304c6a4b79eb25e7bc4 403 Gene3D G3DSA:1.50.10.10 8 402 3.5E-140 T 15-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 C2I28_25360 3911c8e2494de304c6a4b79eb25e7bc4 403 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 40 392 1.0E-104 T 15-10-2018 C2I28_25360 3911c8e2494de304c6a4b79eb25e7bc4 403 SUPERFAMILY SSF48208 17 401 1.91E-107 T 15-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 C2I28_17665 ddb3cc33c79acd786ca868be5a93fe25 214 Gene3D G3DSA:1.20.1280.250 1 84 1.3E-12 T 15-10-2018 IPR038344 EF-G binding protein, N-terminal domain superfamily C2I28_17665 ddb3cc33c79acd786ca868be5a93fe25 214 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 100 199 4.5E-8 T 15-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger C2I28_17665 ddb3cc33c79acd786ca868be5a93fe25 214 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 86 7.4E-27 T 15-10-2018 IPR010841 Elongation factor G-binding protein, N-terminal C2I28_10680 dc4b237ddeb3829cd6c1b353116ce2d5 129 SUPERFAMILY SSF55331 2 128 2.75E-41 T 15-10-2018 IPR014347 Tautomerase/MIF superfamily C2I28_10680 dc4b237ddeb3829cd6c1b353116ce2d5 129 Pfam PF14552 Tautomerase enzyme 38 118 4.6E-33 T 15-10-2018 IPR037479 Tautomerase, MSAD family C2I28_10680 dc4b237ddeb3829cd6c1b353116ce2d5 129 Gene3D G3DSA:3.30.429.10 1 129 6.9E-52 T 15-10-2018 IPR014347 Tautomerase/MIF superfamily C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 3.0E-242 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 319 341 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 168 188 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 99 113 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 393 406 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 61 85 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 115 125 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 PRINTS PR00906 SecA protein signature 356 373 3.5E-71 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Pfam PF02810 SEC-C motif 818 836 2.9E-9 T 15-10-2018 IPR004027 SEC-C motif C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Pfam PF00271 Helicase conserved C-terminal domain 418 530 1.6E-5 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 SUPERFAMILY SSF81767 225 348 1.44E-46 T 15-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Gene3D G3DSA:3.40.50.300 15 396 0.0 T 15-10-2018 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 SUPERFAMILY SSF52540 7 395 2.45E-81 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 SUPERFAMILY SSF52540 397 569 1.31E-53 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 SMART SM00958 226 338 1.9E-66 T 15-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 SUPERFAMILY SSF81886 571 826 3.27E-80 T 15-10-2018 IPR036266 SecA, Wing/Scaffold superfamily C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 ProSitePatterns PS01312 SecA family signature. 480 495 - T 15-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 SMART SM00957 5 382 2.0E-281 T 15-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 15-10-2018 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Gene3D G3DSA:1.10.3060.10 571 777 0.0 T 15-10-2018 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Pfam PF01043 SecA preprotein cross-linking domain 230 338 4.8E-41 T 15-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.715 T 15-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Pfam PF07516 SecA Wing and Scaffold domain 568 778 2.0E-65 T 15-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 15-10-2018 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Pfam PF07517 SecA DEAD-like domain 6 382 8.9E-129 T 15-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 C2I28_07060 ed400ffccea1800cb14261646a4d787f 838 Gene3D G3DSA:1.10.1200.230 621 705 0.0 T 15-10-2018 C2I28_15410 5f2db1e5d71e8ffd200bb7ec4188c4d5 314 SUPERFAMILY SSF52317 1 161 2.7E-53 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_15410 5f2db1e5d71e8ffd200bb7ec4188c4d5 314 Gene3D G3DSA:3.40.50.10740 1 158 8.9E-60 T 15-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal C2I28_15410 5f2db1e5d71e8ffd200bb7ec4188c4d5 314 Gene3D G3DSA:3.50.30.60 167 299 4.2E-42 T 15-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I28_15410 5f2db1e5d71e8ffd200bb7ec4188c4d5 314 SUPERFAMILY SSF141986 142 296 1.83E-41 T 15-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I28_15410 5f2db1e5d71e8ffd200bb7ec4188c4d5 314 PIRSF PIRSF028757 1 304 6.4E-95 T 15-10-2018 IPR003507 Peptidase family S66 C2I28_15410 5f2db1e5d71e8ffd200bb7ec4188c4d5 314 Pfam PF02016 LD-carboxypeptidase 13 291 6.7E-84 T 15-10-2018 IPR003507 Peptidase family S66 C2I28_24295 310bfb31ff9180b87cdd0c97234ab4e3 361 Pfam PF02687 FtsX-like permease family 268 351 4.6E-9 T 15-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I28_24295 310bfb31ff9180b87cdd0c97234ab4e3 361 Pfam PF12704 MacB-like periplasmic core domain 21 205 1.7E-6 T 15-10-2018 IPR025857 MacB-like periplasmic core domain C2I28_10995 bf07ce50857a48b280beb724168c429b 292 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 269 4.8E-48 T 15-10-2018 C2I28_10995 bf07ce50857a48b280beb724168c429b 292 Gene3D G3DSA:3.40.50.1000 5 267 5.9E-71 T 15-10-2018 IPR023214 HAD superfamily C2I28_10995 bf07ce50857a48b280beb724168c429b 292 Gene3D G3DSA:3.30.1240.10 84 198 5.9E-71 T 15-10-2018 C2I28_10995 bf07ce50857a48b280beb724168c429b 292 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 243 6.2E-12 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_10995 bf07ce50857a48b280beb724168c429b 292 SUPERFAMILY SSF56784 1 275 8.68E-53 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 317 5.2E-56 T 15-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 Gene3D G3DSA:3.20.20.70 4 304 1.5E-100 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 SUPERFAMILY SSF54862 335 410 1.86E-14 T 15-10-2018 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 Pfam PF01180 Dihydroorotate dehydrogenase 83 301 4.6E-30 T 15-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 Pfam PF14697 4Fe-4S dicluster domain 335 397 1.1E-23 T 15-10-2018 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 Gene3D G3DSA:3.30.70.20 305 415 6.6E-23 T 15-10-2018 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 SUPERFAMILY SSF51395 1 318 4.0E-70 T 15-10-2018 C2I28_03680 69bf6135a43debe86a406b7d3c77128f 426 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 379 390 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_23845 999166ce79e4ad25b3fd4ff99d7ffe0b 189 Pfam PF13302 Acetyltransferase (GNAT) domain 14 150 1.5E-22 T 15-10-2018 IPR000182 GNAT domain C2I28_23845 999166ce79e4ad25b3fd4ff99d7ffe0b 189 SUPERFAMILY SSF55729 7 175 9.33E-44 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_23845 999166ce79e4ad25b3fd4ff99d7ffe0b 189 Gene3D G3DSA:3.40.630.30 2 176 1.8E-49 T 15-10-2018 C2I28_16165 35c58dce48f5727ac356e98b39e1e07f 194 Gene3D G3DSA:1.10.357.10 2 191 3.4E-25 T 15-10-2018 C2I28_16165 35c58dce48f5727ac356e98b39e1e07f 194 SUPERFAMILY SSF46689 3 62 4.49E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_16165 35c58dce48f5727ac356e98b39e1e07f 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.4E-16 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_16165 35c58dce48f5727ac356e98b39e1e07f 194 SUPERFAMILY SSF48498 88 191 1.14E-5 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_16165 35c58dce48f5727ac356e98b39e1e07f 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.6E-9 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_16165 35c58dce48f5727ac356e98b39e1e07f 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.6E-9 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.7E-18 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.7E-18 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.7E-18 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.7E-18 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.7E-18 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 7.3E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 7.3E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 7.3E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 Gene3D G3DSA:3.40.50.720 1 248 5.2E-52 T 15-10-2018 C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 SUPERFAMILY SSF51735 1 207 5.12E-49 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_12740 7df00712b5c95a9279c1f9c77ec44b16 258 Pfam PF00106 short chain dehydrogenase 6 189 5.1E-47 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 SUPERFAMILY SSF55821 20 215 9.77E-67 T 15-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 PIRSF PIRSF004930 1 346 1.9E-131 T 15-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 340 1.7E-26 T 15-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 213 5.1E-65 T 15-10-2018 IPR006070 YrdC-like domain GO:0003725 C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 Gene3D G3DSA:3.90.870.10 5 218 4.2E-84 T 15-10-2018 C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 Pfam PF01300 Telomere recombination 27 202 1.3E-56 T 15-10-2018 IPR006070 YrdC-like domain GO:0003725 C2I28_07400 8f19e0b2922f6859818cd8ab8695b7f1 346 Gene3D G3DSA:3.40.50.11030 221 346 1.3E-41 T 15-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily C2I28_22005 daa582afec6972c179825bd651ca7018 365 Gene3D G3DSA:1.10.10.2840 237 365 6.8E-23 T 15-10-2018 C2I28_22005 daa582afec6972c179825bd651ca7018 365 Pfam PF05651 Putative sugar diacid recognition 5 137 7.3E-51 T 15-10-2018 IPR008599 Putative sugar diacid recognition C2I28_22005 daa582afec6972c179825bd651ca7018 365 Pfam PF13556 PucR C-terminal helix-turn-helix domain 303 360 3.0E-20 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_25670 af8f2442eee7a8183dad0e74cd7f749b 337 SUPERFAMILY SSF52317 1 158 2.56E-37 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_25670 af8f2442eee7a8183dad0e74cd7f749b 337 Gene3D G3DSA:3.50.30.60 162 335 1.8E-33 T 15-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I28_25670 af8f2442eee7a8183dad0e74cd7f749b 337 Pfam PF02016 LD-carboxypeptidase 13 323 2.7E-67 T 15-10-2018 IPR003507 Peptidase family S66 C2I28_25670 af8f2442eee7a8183dad0e74cd7f749b 337 SUPERFAMILY SSF141986 179 327 6.15E-28 T 15-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily C2I28_25670 af8f2442eee7a8183dad0e74cd7f749b 337 Gene3D G3DSA:3.40.50.10740 3 159 4.5E-33 T 15-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal C2I28_25670 af8f2442eee7a8183dad0e74cd7f749b 337 PIRSF PIRSF028757 1 336 2.3E-61 T 15-10-2018 IPR003507 Peptidase family S66 C2I28_01475 fee23a202e158da1804f9083203fbc09 308 SUPERFAMILY SSF103481 41 145 6.54E-16 T 15-10-2018 C2I28_01475 fee23a202e158da1804f9083203fbc09 308 Pfam PF00892 EamA-like transporter family 154 287 7.0E-20 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_01475 fee23a202e158da1804f9083203fbc09 308 Pfam PF00892 EamA-like transporter family 12 141 2.1E-15 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_01475 fee23a202e158da1804f9083203fbc09 308 SUPERFAMILY SSF103481 190 288 3.4E-13 T 15-10-2018 C2I28_13705 a2cf17804eae15ca6131353a1ab72d67 174 Pfam PF08282 haloacid dehalogenase-like hydrolase 78 143 1.4E-9 T 15-10-2018 C2I28_13705 a2cf17804eae15ca6131353a1ab72d67 174 PIRSF PIRSF006118 1 166 7.2E-64 T 15-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_13705 a2cf17804eae15ca6131353a1ab72d67 174 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 4 155 7.6E-52 T 15-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_13705 a2cf17804eae15ca6131353a1ab72d67 174 Gene3D G3DSA:3.40.50.1000 1 174 1.7E-56 T 15-10-2018 IPR023214 HAD superfamily C2I28_13705 a2cf17804eae15ca6131353a1ab72d67 174 SUPERFAMILY SSF56784 1 166 6.67E-41 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 PIRSF PIRSF002181 1 143 3.6E-50 T 15-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 SUPERFAMILY SSF52161 5 143 1.44E-58 T 15-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 15-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 1.6E-64 T 15-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 Pfam PF00572 Ribosomal protein L13 15 139 1.4E-56 T 15-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 Gene3D G3DSA:3.90.1180.10 1 143 1.4E-60 T 15-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08850 ab5b0158264426b51bcc288a3a81e8a1 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 27.308 T 15-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 C2I28_20855 609a434bddedc3456adc0872b89f2eb3 197 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 181 5.0E-52 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_20855 609a434bddedc3456adc0872b89f2eb3 197 SMART SM01207 7 182 7.5E-80 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_20855 609a434bddedc3456adc0872b89f2eb3 197 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 190 9.7E-64 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_20855 609a434bddedc3456adc0872b89f2eb3 197 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 190 20.061 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_08445 45bebefe5136127e2b70d19d7f6fcdcc 321 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 55 - T 15-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 C2I28_08445 45bebefe5136127e2b70d19d7f6fcdcc 321 SMART SM00220 27 280 2.8E-6 T 15-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I28_08445 45bebefe5136127e2b70d19d7f6fcdcc 321 SUPERFAMILY SSF56112 16 233 2.46E-24 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_08445 45bebefe5136127e2b70d19d7f6fcdcc 321 Gene3D G3DSA:1.10.510.10 109 262 3.1E-22 T 15-10-2018 C2I28_08445 45bebefe5136127e2b70d19d7f6fcdcc 321 Pfam PF00069 Protein kinase domain 27 238 5.6E-15 T 15-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I28_08445 45bebefe5136127e2b70d19d7f6fcdcc 321 Gene3D G3DSA:3.30.200.20 13 108 3.1E-22 T 15-10-2018 C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 SUPERFAMILY SSF48498 99 196 1.19E-9 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 SUPERFAMILY SSF46689 3 75 2.29E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 1.1E-15 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 Gene3D G3DSA:1.10.357.10 3 199 7.6E-44 T 15-10-2018 C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.5E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_14615 a4d9c5994463e07fae70147d7cefe7e2 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.5E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_04850 4e3c6512fb6251f0603dc8a355f057cd 110 Pfam PF04327 Cysteine protease Prp 1 106 1.8E-25 T 15-10-2018 IPR007422 Cysteine protease Prp C2I28_04850 4e3c6512fb6251f0603dc8a355f057cd 110 Gene3D G3DSA:3.30.70.1490 1 110 6.4E-34 T 15-10-2018 IPR036764 Cysteine protease Prp superfamily C2I28_04850 4e3c6512fb6251f0603dc8a355f057cd 110 SUPERFAMILY SSF118010 1 108 5.49E-31 T 15-10-2018 IPR036764 Cysteine protease Prp superfamily C2I28_15875 9af2948824f84b688ccd7263a7ec61ba 69 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_15875 9af2948824f84b688ccd7263a7ec61ba 69 Gene3D G3DSA:1.10.8.910 10 68 1.6E-30 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_15875 9af2948824f84b688ccd7263a7ec61ba 69 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_15875 9af2948824f84b688ccd7263a7ec61ba 69 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 2.0E-21 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_09370 e53a0fabb43b984f182709cdcd70bbac 441 PIRSF PIRSF005353 1 441 4.2E-174 T 15-10-2018 IPR026033 Purine permease PbuG-like C2I28_09370 e53a0fabb43b984f182709cdcd70bbac 441 Pfam PF00860 Permease family 16 402 5.5E-45 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 7.0E-118 T 15-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 15-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.88 T 15-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 SUPERFAMILY SSF52518 294 477 9.61E-57 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 Pfam PF02780 Transketolase, C-terminal domain 493 615 2.1E-36 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 SUPERFAMILY SSF52922 490 623 2.49E-38 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 Gene3D G3DSA:3.40.50.970 315 489 5.4E-64 T 15-10-2018 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 Gene3D G3DSA:3.40.50.920 493 628 4.5E-43 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 3.0E-38 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 15-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 2.8E-294 T 15-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 SMART SM00861 316 481 2.6E-61 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_03835 1bf5db157131ac6508cedb22217e096c 633 SUPERFAMILY SSF52518 14 359 1.31E-72 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 269 24.988 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 PIRSF PIRSF000193 4 272 1.1E-73 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 SUPERFAMILY SSF48179 164 272 5.95E-34 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 165 269 5.3E-34 T 15-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 269 3.4E-81 T 15-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 102 2.3E-19 T 15-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 SUPERFAMILY SSF51735 6 163 5.61E-28 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 Gene3D G3DSA:3.40.50.720 1 166 9.3E-45 T 15-10-2018 C2I28_19505 671b9141908e77f4ebc77e809063d2ca 280 Gene3D G3DSA:1.10.3730.10 167 274 2.2E-37 T 15-10-2018 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 Gene3D G3DSA:3.30.1360.60 1 77 2.0E-20 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 Pfam PF02378 Phosphotransferase system, EIIC 126 407 4.4E-36 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 508 625 1.4E-43 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 Pfam PF00367 phosphotransferase system, EIIB 9 42 1.5E-11 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 SUPERFAMILY SSF55604 7 74 5.62E-16 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 506 627 1.7E-49 T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 567 579 - T 15-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 Gene3D G3DSA:2.70.70.10 492 652 5.7E-58 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_00285 8c408f962164f81e99222ae1fd82e3d3 655 SUPERFAMILY SSF51261 505 636 1.27E-52 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 Pfam PF00264 Common central domain of tyrosinase 34 242 5.4E-46 T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 Gene3D G3DSA:1.10.1280.10 1 297 2.7E-115 T 15-10-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 ProSitePatterns PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 224 235 - T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 PRINTS PR00092 Tyrosinase copper-binding domain signature 223 241 2.2E-19 T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 PRINTS PR00092 Tyrosinase copper-binding domain signature 89 94 2.2E-19 T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 PRINTS PR00092 Tyrosinase copper-binding domain signature 203 214 2.2E-19 T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 PRINTS PR00092 Tyrosinase copper-binding domain signature 60 77 2.2E-19 T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 SUPERFAMILY SSF48056 4 287 6.02E-71 T 15-10-2018 IPR008922 Uncharacterised domain, di-copper centre Reactome: R-HSA-5662702 C2I28_24860 cc7f70ba77a2b053c96108724dded4d6 297 ProSitePatterns PS00497 Tyrosinase CuA-binding region signature. 60 77 - T 15-10-2018 IPR002227 Tyrosinase copper-binding domain GO:0016491 Reactome: R-HSA-5662702 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 PRINTS PR00988 Uridine kinase signature 136 146 4.4E-35 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 PRINTS PR00988 Uridine kinase signature 80 95 4.4E-35 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 PRINTS PR00988 Uridine kinase signature 35 46 4.4E-35 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 PRINTS PR00988 Uridine kinase signature 172 185 4.4E-35 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 PRINTS PR00988 Uridine kinase signature 5 22 4.4E-35 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 PRINTS PR00988 Uridine kinase signature 150 161 4.4E-35 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 Hamap MF_00551 Uridine kinase [udk]. 2 206 41.058 T 15-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 SUPERFAMILY SSF52540 3 197 2.91E-51 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 TIGRFAM TIGR00235 udk: uridine kinase 4 206 3.9E-90 T 15-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 Gene3D G3DSA:3.40.50.300 3 210 1.5E-65 T 15-10-2018 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 2.9E-41 T 15-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 C2I28_04565 d193da2806608a31b29c4d1143c3cb3d 211 SMART SM00382 4 154 0.0047 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 SUPERFAMILY SSF55920 1 246 1.57E-89 T 15-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 Gene3D G3DSA:3.90.230.10 1 248 2.2E-106 T 15-10-2018 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 Pfam PF00557 Metallopeptidase family M24 12 239 3.8E-54 T 15-10-2018 IPR000994 Peptidase M24 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 9.4E-23 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 9.4E-23 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 9.4E-23 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 9.4E-23 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 8.3E-100 T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_08795 1fc7aab7a8f282be6e46de5c423814bd 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 42.421 T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 331 9.1E-141 T 15-10-2018 IPR014188 Acrylyl-CoA reductase AcuI C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 SUPERFAMILY SSF50129 7 147 1.08E-40 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 Pfam PF00107 Zinc-binding dehydrogenase 163 276 4.5E-15 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 SMART SM00829 14 329 3.2E-7 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 SUPERFAMILY SSF51735 121 292 6.25E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 90 1.2E-5 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 Gene3D G3DSA:3.40.50.720 130 299 1.6E-120 T 15-10-2018 C2I28_10855 9d7c9318528b6d34414cab595b6310b2 331 Gene3D G3DSA:3.90.180.10 21 330 1.6E-120 T 15-10-2018 C2I28_09580 96429098809e6dfcb04a6fa476435cf7 328 SUPERFAMILY SSF53822 46 269 1.33E-11 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_09580 96429098809e6dfcb04a6fa476435cf7 328 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 45 317 1.5E-38 T 15-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 C2I28_09580 96429098809e6dfcb04a6fa476435cf7 328 Gene3D G3DSA:3.40.50.2300 148 312 1.2E-60 T 15-10-2018 C2I28_09580 96429098809e6dfcb04a6fa476435cf7 328 Gene3D G3DSA:3.40.50.2300 56 299 1.2E-60 T 15-10-2018 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Gene3D G3DSA:3.30.70.3400 34 123 8.0E-23 T 15-10-2018 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 SUPERFAMILY SSF82866 213 416 5.23E-37 T 15-10-2018 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Pfam PF07549 SecD/SecF GG Motif 472 499 6.2E-7 T 15-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 408 1.3E-105 T 15-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Gene3D G3DSA:1.20.1640.10 554 745 6.9E-8 T 15-10-2018 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 479 722 3.1E-69 T 15-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Gene3D G3DSA:1.20.1640.10 224 424 3.4E-15 T 15-10-2018 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 SUPERFAMILY SSF82866 556 734 3.92E-34 T 15-10-2018 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 450 733 26.06 T 15-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 422 34.685 T 15-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 PRINTS PR01755 Bacterial translocase SecF protein signature 670 685 6.0E-25 T 15-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 PRINTS PR01755 Bacterial translocase SecF protein signature 477 492 6.0E-25 T 15-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 PRINTS PR01755 Bacterial translocase SecF protein signature 587 601 6.0E-25 T 15-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 PRINTS PR01755 Bacterial translocase SecF protein signature 635 653 6.0E-25 T 15-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Pfam PF02355 Protein export membrane protein 554 730 3.2E-65 T 15-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 Pfam PF02355 Protein export membrane protein 246 407 3.8E-15 T 15-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 186 401 1.2E-56 T 15-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I28_04720 e61c20da5d86cb1934da29792a8eec47 745 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 499 719 6.2E-52 T 15-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial C2I28_25805 604b9cb93ab6e0fdcbcca569c74ddc4a 197 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 133 192 4.0E-18 T 15-10-2018 C2I28_25805 604b9cb93ab6e0fdcbcca569c74ddc4a 197 PIRSF PIRSF021308 1 197 8.4E-96 T 15-10-2018 IPR016786 Uncharacterised protein YdeI, bacterial C2I28_25805 604b9cb93ab6e0fdcbcca569c74ddc4a 197 SUPERFAMILY SSF159888 9 127 2.88E-21 T 15-10-2018 C2I28_25805 604b9cb93ab6e0fdcbcca569c74ddc4a 197 Pfam PF08818 Domain of unknown function (DU1801) 20 117 5.8E-15 T 15-10-2018 IPR014922 Domain of unknown function DUF1801 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 Pfam PF03466 LysR substrate binding domain 87 292 1.4E-45 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 Gene3D G3DSA:3.40.190.10 90 287 2.0E-41 T 15-10-2018 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.8E-17 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 Gene3D G3DSA:1.10.10.10 1 89 1.7E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 SUPERFAMILY SSF53850 86 294 5.16E-43 T 15-10-2018 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 Gene3D G3DSA:3.40.190.10 164 265 2.0E-41 T 15-10-2018 C2I28_22235 5845e0c45c14eefe25eae78cb0096e9d 296 SUPERFAMILY SSF46785 1 110 2.24E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24525 4e457bc7bec995a8de0fbd55943d26a5 180 Gene3D G3DSA:3.40.630.30 13 179 2.2E-37 T 15-10-2018 C2I28_24525 4e457bc7bec995a8de0fbd55943d26a5 180 SUPERFAMILY SSF55729 15 179 1.3E-28 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24525 4e457bc7bec995a8de0fbd55943d26a5 180 Pfam PF00583 Acetyltransferase (GNAT) family 52 153 4.1E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_16055 d92f1e32674df4e6abdc5a7fb27ac692 422 Pfam PF07690 Major Facilitator Superfamily 27 368 5.1E-41 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_16055 d92f1e32674df4e6abdc5a7fb27ac692 422 SUPERFAMILY SSF103473 4 413 1.44E-66 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_16055 d92f1e32674df4e6abdc5a7fb27ac692 422 Gene3D G3DSA:1.20.1250.20 1 420 1.0E-62 T 15-10-2018 C2I28_06910 c586d5ea81dedc363900131562916bf5 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 241 36.562 T 15-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 C2I28_06910 c586d5ea81dedc363900131562916bf5 244 Gene3D G3DSA:3.20.20.70 1 243 9.2E-88 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_06910 c586d5ea81dedc363900131562916bf5 244 SUPERFAMILY SSF51366 5 240 1.49E-69 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_06910 c586d5ea81dedc363900131562916bf5 244 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 6 237 4.8E-84 T 15-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 C2I28_06910 c586d5ea81dedc363900131562916bf5 244 Pfam PF00977 Histidine biosynthesis protein 5 234 2.9E-75 T 15-10-2018 IPR006062 Histidine biosynthesis GO:0000105 C2I28_25325 ceae157a276b9b5ff64d4089476e1085 290 SUPERFAMILY SSF52091 161 265 1.86E-15 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_25325 ceae157a276b9b5ff64d4089476e1085 290 Pfam PF01740 STAS domain 167 262 6.0E-12 T 15-10-2018 IPR002645 STAS domain C2I28_25325 ceae157a276b9b5ff64d4089476e1085 290 Gene3D G3DSA:3.30.750.24 158 274 3.5E-36 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 83 107 - T 15-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 SUPERFAMILY SSF103473 14 254 1.27E-24 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 157 169 - T 15-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 15 492 4.8E-138 T 15-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 Gene3D G3DSA:1.20.1250.20 1 496 2.5E-156 T 15-10-2018 C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 SUPERFAMILY SSF103473 224 490 7.85E-14 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_18090 b7f653fbcc45069464db6af1b58ae5fb 496 Pfam PF00854 POT family 95 463 2.4E-83 T 15-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I28_09705 73902304573318c4715dcf11a3bca0e2 139 SUPERFAMILY SSF82784 1 138 1.57E-40 T 15-10-2018 IPR036102 OsmC/Ohr superfamily C2I28_09705 73902304573318c4715dcf11a3bca0e2 139 Gene3D G3DSA:2.20.25.10 1 44 3.4E-11 T 15-10-2018 C2I28_09705 73902304573318c4715dcf11a3bca0e2 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 138 1.2E-47 T 15-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 C2I28_09705 73902304573318c4715dcf11a3bca0e2 139 Gene3D G3DSA:3.30.300.20 45 139 2.2E-32 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_09705 73902304573318c4715dcf11a3bca0e2 139 Pfam PF02566 OsmC-like protein 42 137 7.0E-20 T 15-10-2018 IPR003718 OsmC/Ohr family C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 319 24.53 T 15-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 SUPERFAMILY SSF52402 8 238 2.62E-61 T 15-10-2018 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 Gene3D G3DSA:3.40.50.620 1 129 3.1E-41 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 Gene3D G3DSA:1.20.59.30 245 331 4.2E-29 T 15-10-2018 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 SUPERFAMILY SSF82829 217 323 6.28E-12 T 15-10-2018 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 Gene3D G3DSA:1.10.10.1360 130 215 7.3E-31 T 15-10-2018 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 383 428 1.5E-18 T 15-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 Pfam PF01171 PP-loop family 21 204 1.6E-62 T 15-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 208 1.5E-63 T 15-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 Pfam PF11734 TilS substrate C-terminal domain 383 446 3.9E-14 T 15-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 SUPERFAMILY SSF56037 334 456 2.54E-19 T 15-10-2018 C2I28_08450 ef2d673878a7be7d56edae7a7c86b20d 458 SMART SM00977 383 455 5.9E-24 T 15-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 15-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 SUPERFAMILY SSF51621 8 423 2.06E-158 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 Pfam PF00463 Isocitrate lyase family 247 423 3.8E-51 T 15-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 Pfam PF00463 Isocitrate lyase family 11 246 1.1E-57 T 15-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 7 246 1.1E-104 T 15-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 Gene3D G3DSA:3.20.20.60 5 406 1.0E-171 T 15-10-2018 C2I28_11335 b8dd81ce2436cad947307dcada252948 427 PIRSF PIRSF001362 1 426 2.6E-240 T 15-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 Gene3D G3DSA:3.40.50.2300 1 123 9.5E-38 T 15-10-2018 C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 SMART SM00448 2 112 9.5E-41 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 SUPERFAMILY SSF52172 1 172 3.42E-42 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 1.6E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 Pfam PF00072 Response regulator receiver domain 4 113 8.0E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 Gene3D G3DSA:1.10.10.10 124 223 1.6E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18400 d6139a527d0920e922e941fedbc0b153 224 SMART SM00862 144 221 1.4E-20 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_17590 bc98622b1d34cd717d6ff7f46e2d7452 247 Gene3D G3DSA:3.30.240.20 189 247 2.5E-13 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_17590 bc98622b1d34cd717d6ff7f46e2d7452 247 Gene3D G3DSA:3.30.240.20 102 176 1.8E-23 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_17590 bc98622b1d34cd717d6ff7f46e2d7452 247 Pfam PF04239 Protein of unknown function (DUF421) 110 224 1.8E-33 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_15920 aa3a8cd2031d8f1609d87ae8cf91211c 268 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 265 4.3E-122 T 15-10-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 C2I28_15920 aa3a8cd2031d8f1609d87ae8cf91211c 268 Pfam PF03609 PTS system sorbose-specific iic component 4 234 2.2E-70 T 15-10-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 SMART SM00342 184 266 3.3E-27 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 Pfam PF12833 Helix-turn-helix domain 191 267 2.7E-17 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 Gene3D G3DSA:1.10.10.60 160 217 1.1E-11 T 15-10-2018 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 Gene3D G3DSA:1.10.10.60 218 273 4.3E-15 T 15-10-2018 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 SUPERFAMILY SSF46689 220 267 1.03E-9 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 SUPERFAMILY SSF46689 170 217 1.61E-7 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 Pfam PF02311 AraC-like ligand binding domain 16 147 4.4E-21 T 15-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 Gene3D G3DSA:2.60.120.10 22 105 1.3E-8 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_24185 b2a1ee286a3317adcd635b4968dcebab 277 SUPERFAMILY SSF51215 23 152 2.09E-26 T 15-10-2018 IPR037923 Transcription regulator HTH-like C2I28_21695 89a230f00ea841ff5e625e68168bb825 214 SMART SM00850 116 213 5.2E-29 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_21695 89a230f00ea841ff5e625e68168bb825 214 Gene3D G3DSA:2.40.50.40 106 176 9.3E-29 T 15-10-2018 C2I28_21695 89a230f00ea841ff5e625e68168bb825 214 Gene3D G3DSA:2.20.25.10 177 214 2.1E-24 T 15-10-2018 C2I28_21695 89a230f00ea841ff5e625e68168bb825 214 Pfam PF04397 LytTr DNA-binding domain 118 212 2.5E-28 T 15-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 PRINTS PR00116 Arginase signature 116 131 4.4E-12 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 PRINTS PR00116 Arginase signature 229 258 4.4E-12 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 PIRSF PIRSF036979 9 308 7.9E-89 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 ProSitePatterns PS01053 Arginase family signature. 232 253 - T 15-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 TIGRFAM TIGR01230 agmatinase: agmatinase 19 299 1.2E-62 T 15-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 Gene3D G3DSA:3.40.800.10 2 310 5.1E-100 T 15-10-2018 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 Pfam PF00491 Arginase family 30 300 1.6E-83 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_12510 263baf88b4e258671a822d92db18dc3e 318 SUPERFAMILY SSF52768 19 304 5.76E-92 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Pfam PF01476 LysM domain 104 146 9.5E-15 T 15-10-2018 IPR018392 LysM domain C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Pfam PF01476 LysM domain 56 98 8.7E-13 T 15-10-2018 IPR018392 LysM domain C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 SUPERFAMILY SSF54106 103 146 4.05E-11 T 15-10-2018 C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Gene3D G3DSA:3.10.350.10 53 98 1.5E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Gene3D G3DSA:3.10.350.10 100 150 1.7E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Pfam PF00704 Glycosyl hydrolases family 18 223 469 6.1E-30 T 15-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Gene3D G3DSA:3.20.20.80 196 476 1.7E-78 T 15-10-2018 C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 SUPERFAMILY SSF51445 188 478 3.86E-43 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 SUPERFAMILY SSF54106 54 98 3.01E-10 T 15-10-2018 C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 SMART SM00636 174 471 1.3E-18 T 15-10-2018 IPR011583 Chitinase II GO:0008061 C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 Gene3D G3DSA:3.10.50.10 384 442 1.7E-78 T 15-10-2018 IPR029070 Chitinase insertion domain superfamily C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 SMART SM00257 103 146 1.6E-15 T 15-10-2018 IPR018392 LysM domain C2I28_15540 47741226e898cafe60a420e8fd6049ee 481 SMART SM00257 55 98 1.9E-14 T 15-10-2018 IPR018392 LysM domain C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Pfam PF14450 Cell division protein FtsA 205 366 7.7E-23 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 SUPERFAMILY SSF53067 198 368 1.09E-40 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 430 30.979 T 15-10-2018 IPR020823 Cell division protein FtsA C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Gene3D G3DSA:3.30.420.40 10 362 2.2E-114 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Pfam PF14450 Cell division protein FtsA 9 187 2.1E-10 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 PIRSF PIRSF003101 1 430 2.5E-151 T 15-10-2018 IPR020823 Cell division protein FtsA C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 2.2E-29 T 15-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Gene3D G3DSA:3.30.420.40 195 349 2.2E-114 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Gene3D G3DSA:3.30.1490.110 83 167 2.2E-114 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 SUPERFAMILY SSF53067 6 194 4.86E-62 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 Gene3D G3DSA:3.90.640.10 233 298 2.2E-114 T 15-10-2018 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 SMART SM00842 7 194 2.1E-100 T 15-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 C2I28_02940 f0fa30e98d074a75291ca3e03049651b 431 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 7.0E-129 T 15-10-2018 IPR020823 Cell division protein FtsA C2I28_18605 c9805081036ffc2e0a6059c068d234b3 154 Pfam PF00583 Acetyltransferase (GNAT) family 39 130 4.5E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_18605 c9805081036ffc2e0a6059c068d234b3 154 SUPERFAMILY SSF55729 26 152 3.77E-23 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18605 c9805081036ffc2e0a6059c068d234b3 154 Gene3D G3DSA:3.40.630.30 2 154 8.7E-42 T 15-10-2018 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 SUPERFAMILY SSF52313 6 233 1.01E-101 T 15-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 15-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 Gene3D G3DSA:3.40.50.10490 8 219 4.4E-98 T 15-10-2018 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 15-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 9.3E-115 T 15-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 Gene3D G3DSA:1.10.287.610 103 150 4.4E-98 T 15-10-2018 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 Pfam PF00318 Ribosomal protein S2 9 224 7.0E-104 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.326 T 15-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 PRINTS PR00395 Ribosomal protein S2 signature 87 104 5.6E-41 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 PRINTS PR00395 Ribosomal protein S2 signature 175 186 5.6E-41 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 PRINTS PR00395 Ribosomal protein S2 signature 6 24 5.6E-41 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 PRINTS PR00395 Ribosomal protein S2 signature 37 46 5.6E-41 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 PRINTS PR00395 Ribosomal protein S2 signature 158 175 5.6E-41 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02390 f5dc6e0d7ba5ce8e9c17da4a99eb029e 239 PRINTS PR00395 Ribosomal protein S2 signature 196 210 5.6E-41 T 15-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_22270 a2205167655b3b0f621a049292687f35 170 Gene3D G3DSA:3.40.50.300 1 169 3.0E-15 T 15-10-2018 C2I28_22270 a2205167655b3b0f621a049292687f35 170 SUPERFAMILY SSF52540 2 167 2.63E-16 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 SUPERFAMILY SSF47090 105 170 1.41E-20 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 SUPERFAMILY SSF54001 268 390 2.35E-41 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Pfam PF00877 NlpC/P60 family 286 388 8.9E-29 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Gene3D G3DSA:1.10.101.10 182 256 1.6E-22 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Gene3D G3DSA:1.10.101.10 100 174 5.6E-24 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Gene3D G3DSA:3.90.1720.10 271 391 1.5E-42 T 15-10-2018 C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 SUPERFAMILY SSF47090 27 92 4.08E-20 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Gene3D G3DSA:1.10.101.10 27 94 5.2E-20 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Pfam PF01471 Putative peptidoglycan binding domain 115 170 2.6E-19 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Pfam PF01471 Putative peptidoglycan binding domain 196 251 1.0E-17 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 Pfam PF01471 Putative peptidoglycan binding domain 36 92 1.2E-17 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_23185 86cf21f69126707f5004dcf790d46e19 391 SUPERFAMILY SSF47090 187 254 1.49E-20 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_01875 8bd71db125689dd7516450d721231217 385 Pfam PF07690 Major Facilitator Superfamily 7 338 1.2E-13 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_01875 8bd71db125689dd7516450d721231217 385 SUPERFAMILY SSF103473 6 370 2.88E-28 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_01875 8bd71db125689dd7516450d721231217 385 Gene3D G3DSA:1.20.1250.20 195 373 1.9E-9 T 15-10-2018 C2I28_01875 8bd71db125689dd7516450d721231217 385 Gene3D G3DSA:1.20.1250.20 5 188 1.2E-8 T 15-10-2018 C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 Gene3D G3DSA:3.40.50.12780 1 406 1.0E-128 T 15-10-2018 C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 PRINTS PR00154 AMP-binding signature 175 183 6.2E-5 T 15-10-2018 IPR020459 AMP-binding C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 PRINTS PR00154 AMP-binding signature 163 174 6.2E-5 T 15-10-2018 IPR020459 AMP-binding C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 496 4.7E-21 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 Gene3D G3DSA:3.30.300.310 409 510 1.7E-35 T 15-10-2018 C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 SUPERFAMILY SSF56801 3 508 5.1E-166 T 15-10-2018 C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 Pfam PF00501 AMP-binding enzyme 8 413 2.4E-116 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_11210 48165ca1ac9899ac10c7e08f34c4380b 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 465 7.0E-239 T 15-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 209 222 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 108 116 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 133 148 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 343 354 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 195 208 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 286 300 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 82 95 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 119 132 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 PRINTS PR00415 Aconitase family signature 399 412 3.9E-44 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 15-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 Gene3D G3DSA:3.30.499.20 5 286 1.8E-101 T 15-10-2018 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 466 58.013 T 15-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 Pfam PF00330 Aconitase family (aconitate hydratase) 8 457 1.1E-156 T 15-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 Gene3D G3DSA:3.30.499.10 327 471 1.8E-48 T 15-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 15-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 C2I28_05025 28d402bace5e7c1f5dbd2e8e41af6eef 471 SUPERFAMILY SSF53732 2 466 2.22E-166 T 15-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 194 8.1E-28 T 15-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 PIRSF PIRSF006493 1 277 6.9E-77 T 15-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 SUPERFAMILY SSF100939 3 253 1.53E-37 T 15-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 2 255 28.057 T 15-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 SMART SM00559 53 184 1.7E-27 T 15-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 TIGRFAM TIGR02772 Ku_bact: Ku protein 3 255 8.5E-76 T 15-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type C2I28_20920 deb10693ce1b344b90539194c72f1b18 277 Gene3D G3DSA:2.40.290.10 3 183 2.1E-15 T 15-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily C2I28_24605 617a6519d506601a84bdfd560d99734e 183 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 15-10-2018 IPR001455 TusA-like domain C2I28_24605 617a6519d506601a84bdfd560d99734e 183 Pfam PF01206 Sulfurtransferase TusA 8 75 5.8E-22 T 15-10-2018 IPR001455 TusA-like domain C2I28_24605 617a6519d506601a84bdfd560d99734e 183 SUPERFAMILY SSF64307 3 76 1.44E-23 T 15-10-2018 IPR036868 TusA-like domain superfamily C2I28_24605 617a6519d506601a84bdfd560d99734e 183 Gene3D G3DSA:3.30.110.40 1 76 6.7E-28 T 15-10-2018 IPR036868 TusA-like domain superfamily C2I28_24605 617a6519d506601a84bdfd560d99734e 183 SMART SM00450 89 183 6.6E-20 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24605 617a6519d506601a84bdfd560d99734e 183 Pfam PF00581 Rhodanese-like domain 90 179 8.5E-15 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24605 617a6519d506601a84bdfd560d99734e 183 Gene3D G3DSA:3.40.250.10 86 183 3.0E-27 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_24605 617a6519d506601a84bdfd560d99734e 183 SUPERFAMILY SSF52821 81 179 5.76E-30 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 SUPERFAMILY SSF51690 109 275 1.49E-57 T 15-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 PIRSF PIRSF006250 1 278 1.7E-97 T 15-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 107 3.7E-28 T 15-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 Gene3D G3DSA:3.90.1170.20 14 273 1.0E-102 T 15-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 SUPERFAMILY SSF54675 2 108 5.1E-30 T 15-10-2018 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 274 6.4E-102 T 15-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 274 3.9E-61 T 15-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 C2I28_04805 57266c2adbcf283ea3dfcfc5ebaa5175 297 Gene3D G3DSA:3.20.20.70 123 265 1.0E-102 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 50 4.9E-14 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 Gene3D G3DSA:1.10.10.60 385 442 6.2E-24 T 15-10-2018 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 Gene3D G3DSA:1.10.10.1330 89 218 4.8E-22 T 15-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 331 350 - T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 PRINTS PR00045 Sigma-54 factor signature 156 173 1.1E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 PRINTS PR00045 Sigma-54 factor signature 418 436 1.1E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 PRINTS PR00045 Sigma-54 factor signature 343 355 1.1E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 PRINTS PR00045 Sigma-54 factor signature 359 370 1.1E-24 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 PIRSF PIRSF000774 1 444 9.4E-138 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 13 442 1.7E-132 T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 423 430 - T 15-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 Pfam PF04963 Sigma-54 factor, core binding domain 84 270 3.2E-47 T 15-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 C2I28_12685 ac8fc77232e3c8de9266031fc3dbd0a2 444 Pfam PF04552 Sigma-54, DNA binding domain 284 443 1.9E-63 T 15-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 Gene3D G3DSA:3.40.50.1820 5 268 1.2E-72 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 267 37.989 T 15-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 SUPERFAMILY SSF53474 3 266 7.78E-59 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 7.6E-11 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 7.6E-11 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 7.6E-11 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 19 266 1.4E-87 T 15-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 C2I28_06000 981491940398dcd32ca34fd1629d7e27 269 Pfam PF00561 alpha/beta hydrolase fold 20 149 1.0E-27 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_07365 f2d36c9342c09541d702d24a4a4c83b2 383 Gene3D G3DSA:3.40.50.2000 192 352 8.2E-156 T 15-10-2018 C2I28_07365 f2d36c9342c09541d702d24a4a4c83b2 383 SUPERFAMILY SSF53756 5 372 6.91E-137 T 15-10-2018 C2I28_07365 f2d36c9342c09541d702d24a4a4c83b2 383 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 1.4E-165 T 15-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 C2I28_07365 f2d36c9342c09541d702d24a4a4c83b2 383 Gene3D G3DSA:3.40.50.2000 7 363 8.2E-156 T 15-10-2018 C2I28_07365 f2d36c9342c09541d702d24a4a4c83b2 383 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 365 1.1E-120 T 15-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 Gene3D G3DSA:3.30.565.10 269 423 2.5E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 270 1.7E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 422 3.8E-18 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 Pfam PF07694 5TMR of 5TMR-LYT 47 170 6.3E-6 T 15-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 SUPERFAMILY SSF55874 276 422 9.17E-34 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 SUPERFAMILY SSF47384 205 271 2.16E-13 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 SMART SM00387 318 424 4.8E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 SMART SM00388 210 275 6.6E-13 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 Gene3D G3DSA:1.10.287.130 213 268 3.3E-16 T 15-10-2018 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 2.1E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 421 2.1E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 2.1E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_01250 c8d8257d1978d3e3da8c7f1e6b88326f 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 402 2.1E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 PIRSF PIRSF000097 1 280 4.4E-79 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 Gene3D G3DSA:3.20.20.100 1 278 2.1E-100 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 42 59 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 PRINTS PR00069 Aldo-keto reductase signature 160 189 4.4E-43 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 PRINTS PR00069 Aldo-keto reductase signature 198 222 4.4E-43 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 PRINTS PR00069 Aldo-keto reductase signature 94 112 4.4E-43 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 PRINTS PR00069 Aldo-keto reductase signature 126 143 4.4E-43 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 PRINTS PR00069 Aldo-keto reductase signature 38 62 4.4E-43 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 SUPERFAMILY SSF51430 8 266 1.44E-83 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_15665 8e26fd88a6c82a8af21dd813fcf03e2d 280 Pfam PF00248 Aldo/keto reductase family 19 263 1.1E-45 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_25850 8117f8b6d0dd1374a5864c08c8f8d7c3 135 SUPERFAMILY SSF69118 6 122 5.14E-27 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_25850 8117f8b6d0dd1374a5864c08c8f8d7c3 135 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 119 2.5E-14 T 15-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_25850 8117f8b6d0dd1374a5864c08c8f8d7c3 135 Gene3D G3DSA:1.20.1290.10 5 131 3.5E-33 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_03620 1660990eecb85ff55256095d11a7c698 71 Gene3D G3DSA:3.40.5.90 2 66 5.0E-15 T 15-10-2018 C2I28_03620 1660990eecb85ff55256095d11a7c698 71 SMART SM00704 25 60 9.3E-4 T 15-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 C2I28_03620 1660990eecb85ff55256095d11a7c698 71 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 55 1.3E-18 T 15-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 C2I28_23335 298f6d639886e1a43c525f9cf1b53b02 91 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 1.1E-8 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_23335 298f6d639886e1a43c525f9cf1b53b02 91 Gene3D G3DSA:2.10.260.10 1 54 2.7E-25 T 15-10-2018 C2I28_23335 298f6d639886e1a43c525f9cf1b53b02 91 SMART SM00966 8 51 2.9E-9 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_23335 298f6d639886e1a43c525f9cf1b53b02 91 SUPERFAMILY SSF89447 1 51 4.71E-16 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_23335 298f6d639886e1a43c525f9cf1b53b02 91 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 3.2E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_20780 840672af83f2527d2db151934740ef55 237 Gene3D G3DSA:1.10.30.40 3 53 3.5E-14 T 15-10-2018 C2I28_20780 840672af83f2527d2db151934740ef55 237 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 8 235 1.5E-80 T 15-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 C2I28_20780 840672af83f2527d2db151934740ef55 237 PIRSF PIRSF018982 1 237 2.2E-85 T 15-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 C2I28_20780 840672af83f2527d2db151934740ef55 237 Gene3D G3DSA:3.40.50.11240 55 235 2.3E-63 T 15-10-2018 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 SUPERFAMILY SSF55021 349 422 3.44E-13 T 15-10-2018 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 SUPERFAMILY SSF55347 138 303 1.31E-52 T 15-10-2018 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 Gene3D G3DSA:3.30.70.260 345 418 1.4E-148 T 15-10-2018 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 SUPERFAMILY SSF51735 1 159 2.28E-35 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 Gene3D G3DSA:3.30.360.10 137 344 1.4E-148 T 15-10-2018 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 15-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 Gene3D G3DSA:3.40.50.720 5 338 1.4E-148 T 15-10-2018 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 PIRSF PIRSF000098 2 430 2.6E-171 T 15-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 6.6E-26 T 15-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 Pfam PF01842 ACT domain 351 416 4.9E-14 T 15-10-2018 IPR002912 ACT domain C2I28_06435 d6168f80d74fa5c28b5174e75cb21a73 433 Pfam PF00742 Homoserine dehydrogenase 138 316 9.5E-66 T 15-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 C2I28_15550 8e657f97c8f82f0a97b9fa396080ee75 302 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 262 8.8E-119 T 15-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I28_15550 8e657f97c8f82f0a97b9fa396080ee75 302 Gene3D G3DSA:3.90.550.10 1 292 1.2E-91 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_15550 8e657f97c8f82f0a97b9fa396080ee75 302 Pfam PF00483 Nucleotidyl transferase 6 256 3.5E-30 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_15550 8e657f97c8f82f0a97b9fa396080ee75 302 SUPERFAMILY SSF53448 2 265 2.82E-68 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 SUPERFAMILY SSF52540 296 529 4.14E-37 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 SUPERFAMILY SSF52540 2 250 1.27E-45 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 Pfam PF00005 ABC transporter 18 184 7.1E-22 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 Gene3D G3DSA:3.40.50.300 1 281 1.4E-56 T 15-10-2018 C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 Pfam PF00005 ABC transporter 335 468 5.1E-14 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 Pfam PF12848 ABC transporter 224 308 2.6E-19 T 15-10-2018 IPR032781 ABC-transporter extension domain C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 Gene3D G3DSA:3.40.50.300 284 538 9.2E-42 T 15-10-2018 C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 SMART SM00382 344 513 0.087 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_19095 d86c30f7bbc4909f33040eb5b29cb12f 539 SMART SM00382 26 238 3.9E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14060 8f3f62318027d1c84770730bbff6a972 424 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 204 384 4.8E-41 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_14060 8f3f62318027d1c84770730bbff6a972 424 SMART SM00283 157 424 9.0E-57 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_14060 8f3f62318027d1c84770730bbff6a972 424 Gene3D G3DSA:1.10.287.950 77 419 6.7E-61 T 15-10-2018 C2I28_14060 8f3f62318027d1c84770730bbff6a972 424 SMART SM00304 75 128 4.7E-4 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_14060 8f3f62318027d1c84770730bbff6a972 424 SUPERFAMILY SSF58104 101 419 6.54E-62 T 15-10-2018 C2I28_01565 472e16597a502973b2430900fd8d70ef 375 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 371 5.2E-87 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_01565 472e16597a502973b2430900fd8d70ef 375 Gene3D G3DSA:3.30.300.210 220 374 9.3E-39 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_01565 472e16597a502973b2430900fd8d70ef 375 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 205 370 8.0E-30 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.1E-39 T 15-10-2018 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.1E-39 T 15-10-2018 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.1E-39 T 15-10-2018 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.1E-39 T 15-10-2018 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.1E-39 T 15-10-2018 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 15-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 SUPERFAMILY SSF51905 2 303 1.41E-58 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 5.0E-121 T 15-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 Gene3D G3DSA:3.50.50.60 8 301 6.7E-117 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 7.3E-53 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 3.8E-73 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_06890 b01da274f961c4b2cff0f9722abbb001 317 Gene3D G3DSA:3.50.50.60 117 240 6.7E-117 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_03315 159b331d2b77821997701087399c1b2d 310 Gene3D G3DSA:2.40.10.420 275 310 3.8E-22 T 15-10-2018 C2I28_03315 159b331d2b77821997701087399c1b2d 310 Gene3D G3DSA:1.10.101.10 28 111 2.4E-17 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_03315 159b331d2b77821997701087399c1b2d 310 Gene3D G3DSA:1.10.10.2520 195 274 4.3E-32 T 15-10-2018 C2I28_03315 159b331d2b77821997701087399c1b2d 310 Pfam PF01471 Putative peptidoglycan binding domain 44 96 6.3E-13 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_03315 159b331d2b77821997701087399c1b2d 310 Pfam PF07486 Cell Wall Hydrolase 211 309 2.3E-28 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_03315 159b331d2b77821997701087399c1b2d 310 SUPERFAMILY SSF47090 33 101 3.92E-17 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_03315 159b331d2b77821997701087399c1b2d 310 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 32 310 6.6E-98 T 15-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 C2I28_12045 ccbff27b663bc11df60f846e0b119eec 109 SUPERFAMILY SSF46973 2 99 3.27E-37 T 15-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 C2I28_12045 ccbff27b663bc11df60f846e0b119eec 109 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 99 4.2E-38 T 15-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I28_12045 ccbff27b663bc11df60f846e0b119eec 109 Gene3D G3DSA:1.20.58.280 1 105 2.0E-40 T 15-10-2018 C2I28_12045 ccbff27b663bc11df60f846e0b119eec 109 PIRSF PIRSF000699 1 104 3.4E-39 T 15-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 C2I28_04755 67898ea141209da62b05afe425493d6c 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 47.231 T 15-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I28_04755 67898ea141209da62b05afe425493d6c 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 3.2E-144 T 15-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I28_04755 67898ea141209da62b05afe425493d6c 342 SUPERFAMILY SSF111337 2 342 1.31E-141 T 15-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I28_04755 67898ea141209da62b05afe425493d6c 342 Gene3D G3DSA:2.40.10.240 64 162 2.1E-138 T 15-10-2018 C2I28_04755 67898ea141209da62b05afe425493d6c 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 342 1.7E-152 T 15-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 C2I28_04755 67898ea141209da62b05afe425493d6c 342 Gene3D G3DSA:3.40.1780.10 14 341 2.1E-138 T 15-10-2018 C2I28_24150 796e739185c7f824028e8716b1371ef4 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_24150 796e739185c7f824028e8716b1371ef4 192 SUPERFAMILY SSF48498 81 164 1.16E-5 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_24150 796e739185c7f824028e8716b1371ef4 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.5E-17 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_24150 796e739185c7f824028e8716b1371ef4 192 Gene3D G3DSA:1.10.357.10 4 190 8.9E-48 T 15-10-2018 C2I28_24150 796e739185c7f824028e8716b1371ef4 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 8.4E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_24150 796e739185c7f824028e8716b1371ef4 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 8.4E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_24150 796e739185c7f824028e8716b1371ef4 192 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 58 189 4.3E-33 T 15-10-2018 IPR032551 HTH-type transcriptional repressor, C-terminal C2I28_24150 796e739185c7f824028e8716b1371ef4 192 SUPERFAMILY SSF46689 6 73 2.94E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 7.5E-52 T 15-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 Gene3D G3DSA:3.40.50.2020 153 293 3.1E-125 T 15-10-2018 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 SUPERFAMILY SSF53271 75 308 1.63E-66 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 SMART SM01400 10 126 1.8E-80 T 15-10-2018 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 317 51.513 T 15-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 Gene3D G3DSA:3.40.50.2020 13 305 3.1E-125 T 15-10-2018 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 7.7E-23 T 15-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 1.0E-130 T 15-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 C2I28_08360 3ada9fa44cbdf5709481cdb8b7168d66 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 15-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 C2I28_26495 164e7a3a8b5953ed96feb609aaa6ff0c 207 Gene3D G3DSA:3.40.50.150 10 196 2.5E-40 T 15-10-2018 C2I28_26495 164e7a3a8b5953ed96feb609aaa6ff0c 207 SUPERFAMILY SSF53335 11 188 4.56E-41 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_26495 164e7a3a8b5953ed96feb609aaa6ff0c 207 Pfam PF13649 Methyltransferase domain 51 145 2.5E-23 T 15-10-2018 C2I28_04050 d9e00e2bc7b880c4f83f2ca7f646574b 210 Pfam PF00753 Metallo-beta-lactamase superfamily 9 191 1.7E-31 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_04050 d9e00e2bc7b880c4f83f2ca7f646574b 210 SMART SM00849 12 191 1.0E-41 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_04050 d9e00e2bc7b880c4f83f2ca7f646574b 210 SUPERFAMILY SSF56281 1 208 1.57E-53 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_04050 d9e00e2bc7b880c4f83f2ca7f646574b 210 Gene3D G3DSA:3.60.15.10 1 210 1.9E-65 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_17120 1edbb3bed72e7a10c39aec69517d5609 483 Gene3D G3DSA:3.40.309.10 262 441 3.1E-160 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_17120 1edbb3bed72e7a10c39aec69517d5609 483 Gene3D G3DSA:3.40.605.10 27 259 3.1E-160 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_17120 1edbb3bed72e7a10c39aec69517d5609 483 Pfam PF00171 Aldehyde dehydrogenase family 19 476 2.3E-157 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_17120 1edbb3bed72e7a10c39aec69517d5609 483 SUPERFAMILY SSF53720 7 480 2.09E-148 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_17120 1edbb3bed72e7a10c39aec69517d5609 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_17120 1edbb3bed72e7a10c39aec69517d5609 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_17205 e8201115dcc20a22af2434d34f4e1b5f 311 ProDom PD135861 METAL-BINDING IRON CSID GAB CYTOPLASMIC 3D-STRUCTURE HOMOLOG DIRECT SEQUENCING 23 308 2.0E-90 T 15-10-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 C2I28_17205 e8201115dcc20a22af2434d34f4e1b5f 311 Gene3D G3DSA:3.60.130.10 13 311 2.3E-106 T 15-10-2018 C2I28_17205 e8201115dcc20a22af2434d34f4e1b5f 311 Pfam PF08943 CsiD 18 308 2.1E-125 T 15-10-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 C2I28_17205 e8201115dcc20a22af2434d34f4e1b5f 311 SUPERFAMILY SSF51197 14 309 1.37E-72 T 15-10-2018 C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 179 4.2E-49 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 SUPERFAMILY SSF56420 2 177 1.44E-58 T 15-10-2018 IPR036821 Peptide deformylase superfamily C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 Gene3D G3DSA:3.90.45.10 1 184 8.3E-69 T 15-10-2018 IPR036821 Peptide deformylase superfamily C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 PRINTS PR01576 Peptide deformylase signature 121 139 8.5E-29 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 PRINTS PR01576 Peptide deformylase signature 108 119 8.5E-29 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 PRINTS PR01576 Peptide deformylase signature 140 169 8.5E-29 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 PRINTS PR01576 Peptide deformylase signature 47 76 8.5E-29 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 Pfam PF01327 Polypeptide deformylase 4 171 2.3E-46 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 PIRSF PIRSF004749 1 184 6.1E-47 T 15-10-2018 IPR023635 Peptide deformylase C2I28_14755 055c2e04ac44d59c86c0d7ef8da6259a 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.097 T 15-10-2018 IPR023635 Peptide deformylase C2I28_09530 186a3f9545a863afc9b09245a705fe3b 96 SUPERFAMILY SSF141000 4 94 3.79E-32 T 15-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 C2I28_09530 186a3f9545a863afc9b09245a705fe3b 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.645 T 15-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 C2I28_09530 186a3f9545a863afc9b09245a705fe3b 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 1.3E-34 T 15-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 C2I28_09530 186a3f9545a863afc9b09245a705fe3b 96 Gene3D G3DSA:1.10.20.60 1 94 1.8E-32 T 15-10-2018 C2I28_09530 186a3f9545a863afc9b09245a705fe3b 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 3.7E-22 T 15-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Pfam PF08245 Mur ligase middle domain 111 295 3.3E-48 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Gene3D G3DSA:3.40.1390.10 2 83 1.7E-21 T 15-10-2018 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 456 35.352 T 15-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 453 1.0E-139 T 15-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 SUPERFAMILY SSF53623 105 313 2.35E-54 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 394 1.6E-17 T 15-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Gene3D G3DSA:3.90.190.20 315 459 2.4E-44 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Gene3D G3DSA:3.40.1190.10 87 314 1.2E-70 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 Pfam PF01225 Mur ligase family, catalytic domain 27 101 6.1E-12 T 15-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 SUPERFAMILY SSF53244 316 453 5.86E-38 T 15-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 C2I28_09110 4fea83adb4cb0f0c175ce10644d5d2ff 460 SUPERFAMILY SSF63418 1 102 6.15E-25 T 15-10-2018 IPR035911 MurE/MurF, N-terminal C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 Pfam PF00210 Ferritin-like domain 8 146 2.4E-32 T 15-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 PIRSF PIRSF005900 1 146 3.6E-48 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 3.4E-14 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 3.4E-14 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 3.4E-14 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 SUPERFAMILY SSF47240 5 145 3.92E-46 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 Gene3D G3DSA:1.20.1260.10 1 146 2.2E-53 T 15-10-2018 IPR012347 Ferritin-like C2I28_05905 3cbbfbaac154a210328eb42b701705dd 146 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 15-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 Gene3D G3DSA:3.40.50.720 1 246 5.0E-92 T 15-10-2018 C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 SUPERFAMILY SSF51735 4 246 1.67E-92 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 2.4E-4 T 15-10-2018 C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 7.6E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.6E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 7.6E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-44 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-44 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-44 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-44 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-44 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-44 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11355 6731bd65f8acc0d805e4bfa3cbf6f735 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 3.1E-74 T 15-10-2018 C2I28_25490 90db21507b51c45e70db241512755936 321 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 15-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site C2I28_25490 90db21507b51c45e70db241512755936 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 283 7.6E-64 T 15-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I28_25490 90db21507b51c45e70db241512755936 321 SUPERFAMILY SSF52283 3 134 5.86E-34 T 15-10-2018 C2I28_25490 90db21507b51c45e70db241512755936 321 Gene3D G3DSA:3.40.50.720 5 306 1.5E-112 T 15-10-2018 C2I28_25490 90db21507b51c45e70db241512755936 321 Gene3D G3DSA:3.40.50.720 99 284 1.5E-112 T 15-10-2018 C2I28_25490 90db21507b51c45e70db241512755936 321 SUPERFAMILY SSF51735 104 284 1.98E-59 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_25490 90db21507b51c45e70db241512755936 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 315 1.0E-29 T 15-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I28_07530 7cac74252596a0ba4860a7a47f4f9135 292 TIGRFAM TIGR01230 agmatinase: agmatinase 11 286 7.0E-117 T 15-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 C2I28_07530 7cac74252596a0ba4860a7a47f4f9135 292 Pfam PF00491 Arginase family 23 285 9.2E-79 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_07530 7cac74252596a0ba4860a7a47f4f9135 292 SUPERFAMILY SSF52768 12 290 1.37E-84 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_07530 7cac74252596a0ba4860a7a47f4f9135 292 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 15-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I28_07530 7cac74252596a0ba4860a7a47f4f9135 292 Gene3D G3DSA:3.40.800.10 17 292 2.5E-94 T 15-10-2018 C2I28_07530 7cac74252596a0ba4860a7a47f4f9135 292 PIRSF PIRSF036979 1 292 1.6E-97 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_16685 7916ebcb18eb33d2a0f78ab8557f756b 140 Hamap MF_01624 Arsenate reductase [arsC]. 1 138 48.323 T 15-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 C2I28_16685 7916ebcb18eb33d2a0f78ab8557f756b 140 SUPERFAMILY SSF52788 4 137 1.44E-44 T 15-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily C2I28_16685 7916ebcb18eb33d2a0f78ab8557f756b 140 SMART SM00226 4 138 1.0E-58 T 15-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I28_16685 7916ebcb18eb33d2a0f78ab8557f756b 140 Gene3D G3DSA:3.40.50.2300 1 140 1.0E-57 T 15-10-2018 C2I28_16685 7916ebcb18eb33d2a0f78ab8557f756b 140 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 135 4.2E-70 T 15-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 C2I28_16685 7916ebcb18eb33d2a0f78ab8557f756b 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 135 1.3E-23 T 15-10-2018 IPR023485 Phosphotyrosine protein phosphatase I C2I28_16225 be878af3842c30b5126111a459c7f865 303 SUPERFAMILY SSF47090 99 167 3.4E-22 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_16225 be878af3842c30b5126111a459c7f865 303 Gene3D G3DSA:3.90.1720.10 178 303 2.0E-40 T 15-10-2018 C2I28_16225 be878af3842c30b5126111a459c7f865 303 SUPERFAMILY SSF54001 181 300 2.94E-40 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_16225 be878af3842c30b5126111a459c7f865 303 Gene3D G3DSA:1.10.101.10 99 176 1.0E-23 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_16225 be878af3842c30b5126111a459c7f865 303 Gene3D G3DSA:1.10.101.10 21 98 2.0E-20 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_16225 be878af3842c30b5126111a459c7f865 303 Pfam PF00877 NlpC/P60 family 199 298 5.7E-29 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_16225 be878af3842c30b5126111a459c7f865 303 Pfam PF01471 Putative peptidoglycan binding domain 111 166 1.0E-18 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_16225 be878af3842c30b5126111a459c7f865 303 Pfam PF01471 Putative peptidoglycan binding domain 36 91 1.1E-13 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_16225 be878af3842c30b5126111a459c7f865 303 SUPERFAMILY SSF47090 27 91 2.88E-17 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 642 1.2E-242 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Pfam PF03129 Anticodon binding domain 551 641 3.9E-24 T 15-10-2018 IPR004154 Anticodon-binding C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Pfam PF02824 TGS domain 6 64 1.2E-14 T 15-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 1.3E-16 T 15-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Gene3D G3DSA:3.30.930.10 229 542 1.2E-115 T 15-10-2018 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Gene3D G3DSA:3.30.980.10 72 226 1.2E-65 T 15-10-2018 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 335 363 4.8E-48 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 474 502 4.8E-48 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 517 530 4.8E-48 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 368 391 4.8E-48 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 544 556 4.8E-48 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 SMART SM00863 174 223 1.3E-25 T 15-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 SUPERFAMILY SSF55186 67 245 1.31E-64 T 15-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 645 35.778 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Gene3D G3DSA:3.40.50.800 543 645 2.7E-35 T 15-10-2018 IPR036621 Anticodon-binding domain superfamily C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 SUPERFAMILY SSF52954 539 642 4.83E-31 T 15-10-2018 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Gene3D G3DSA:3.30.54.20 135 191 1.2E-65 T 15-10-2018 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 328 539 7.3E-35 T 15-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 SUPERFAMILY SSF55681 247 536 4.18E-97 T 15-10-2018 C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 Gene3D G3DSA:3.10.20.30 3 65 1.4E-26 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_05320 046d424a9df9c22c7f5ac303394b5c84 645 SUPERFAMILY SSF81271 5 64 3.05E-17 T 15-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 332 3.6E-46 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Gene3D G3DSA:1.20.58.760 414 617 6.8E-78 T 15-10-2018 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 112 604 6.2E-250 T 15-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 SUPERFAMILY SSF140990 414 610 8.63E-75 T 15-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Pfam PF01434 Peptidase family M41 394 603 1.8E-89 T 15-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 SUPERFAMILY SSF52540 155 404 1.58E-74 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 SMART SM00382 196 335 3.6E-26 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Gene3D G3DSA:3.40.50.300 150 333 2.4E-72 T 15-10-2018 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 612 39.019 T 15-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 15-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Gene3D G3DSA:1.10.8.60 334 411 5.6E-30 T 15-10-2018 C2I28_08460 364370e1512126cad7a7c7f2b1481d20 636 Pfam PF06480 FtsH Extracellular 9 105 4.6E-8 T 15-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 C2I28_20245 908c865adc6f42f1edca75c076661cf8 267 Gene3D G3DSA:3.40.50.1980 124 254 1.6E-25 T 15-10-2018 C2I28_20245 908c865adc6f42f1edca75c076661cf8 267 Gene3D G3DSA:3.40.50.1980 1 118 5.4E-25 T 15-10-2018 C2I28_20245 908c865adc6f42f1edca75c076661cf8 267 Pfam PF01497 Periplasmic binding protein 3 230 2.5E-34 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_20245 908c865adc6f42f1edca75c076661cf8 267 SUPERFAMILY SSF53807 2 255 5.56E-59 T 15-10-2018 C2I28_06310 18f3bac376ff07bc48fbd6a0da10eb7f 390 Pfam PF00155 Aminotransferase class I and II 38 385 1.5E-45 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_06310 18f3bac376ff07bc48fbd6a0da10eb7f 390 Gene3D G3DSA:3.90.1150.10 14 385 9.8E-155 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_06310 18f3bac376ff07bc48fbd6a0da10eb7f 390 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 6 389 1.5E-152 T 15-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 C2I28_06310 18f3bac376ff07bc48fbd6a0da10eb7f 390 SUPERFAMILY SSF53383 5 386 1.46E-102 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_06310 18f3bac376ff07bc48fbd6a0da10eb7f 390 Gene3D G3DSA:3.40.640.10 69 292 9.8E-155 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 SMART SM00116 259 307 2.2E-5 T 15-10-2018 IPR000644 CBS domain C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 SMART SM00116 200 248 6.2 T 15-10-2018 IPR000644 CBS domain C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Pfam PF03061 Thioesterase superfamily 351 424 8.3E-9 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Gene3D G3DSA:1.10.10.10 5 69 2.6E-6 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 SUPERFAMILY SSF46785 5 54 3.04E-7 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Pfam PF07085 DRTGG domain 76 178 1.4E-29 T 15-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 SUPERFAMILY SSF54637 338 436 1.75E-17 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 58 2.1E-5 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Gene3D G3DSA:3.10.580.10 187 310 5.1E-24 T 15-10-2018 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 SUPERFAMILY SSF75138 72 185 3.66E-29 T 15-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Gene3D G3DSA:3.40.1390.20 70 178 4.8E-25 T 15-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 SUPERFAMILY SSF54631 182 307 2.53E-29 T 15-10-2018 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Gene3D G3DSA:3.10.129.10 311 433 3.4E-9 T 15-10-2018 C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Pfam PF00571 CBS domain 253 307 7.7E-9 T 15-10-2018 IPR000644 CBS domain C2I28_05475 fc843280d1e3d56602257a57a20b2e66 438 Pfam PF00571 CBS domain 196 247 3.7E-5 T 15-10-2018 IPR000644 CBS domain C2I28_15170 d3c9264f1e9eca85d7716a23298f90b9 416 Gene3D G3DSA:3.30.420.10 111 269 4.8E-6 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_15170 d3c9264f1e9eca85d7716a23298f90b9 416 Pfam PF13482 RNase_H superfamily 105 273 3.8E-41 T 15-10-2018 IPR038720 YprB, ribonuclease H-like domain C2I28_15170 d3c9264f1e9eca85d7716a23298f90b9 416 SUPERFAMILY SSF53098 85 281 2.01E-30 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_15170 d3c9264f1e9eca85d7716a23298f90b9 416 Gene3D G3DSA:1.25.40.10 276 397 7.5E-6 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_22785 439d398e902b2447e6c9f51f20eff5fa 401 Gene3D G3DSA:1.20.58.1690 316 400 2.8E-25 T 15-10-2018 IPR038434 YARHG domain superfamily C2I28_22785 439d398e902b2447e6c9f51f20eff5fa 401 SMART SM01324 320 401 1.9E-17 T 15-10-2018 IPR025582 YARHG domain C2I28_22785 439d398e902b2447e6c9f51f20eff5fa 401 Pfam PF13308 YARHG domain 321 401 5.8E-24 T 15-10-2018 IPR025582 YARHG domain C2I28_10975 9155256873ad91fc7f7ee66d68c6ba3d 449 Pfam PF14398 YheC/D like ATP-grasp 183 436 1.5E-79 T 15-10-2018 IPR026838 Endospore coat-associated protein YheC/D C2I28_10975 9155256873ad91fc7f7ee66d68c6ba3d 449 SUPERFAMILY SSF56059 193 420 6.8E-12 T 15-10-2018 C2I28_16745 16602e2b61919e13efc8ce4b205d4ea1 377 SUPERFAMILY SSF56796 3 367 1.3E-78 T 15-10-2018 C2I28_16745 16602e2b61919e13efc8ce4b205d4ea1 377 Gene3D G3DSA:3.40.50.1970 2 157 2.0E-35 T 15-10-2018 C2I28_16745 16602e2b61919e13efc8ce4b205d4ea1 377 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 148 176 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_16745 16602e2b61919e13efc8ce4b205d4ea1 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 358 4.3E-62 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_16745 16602e2b61919e13efc8ce4b205d4ea1 377 PIRSF PIRSF000112 1 370 3.5E-87 T 15-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 C2I28_16745 16602e2b61919e13efc8ce4b205d4ea1 377 Gene3D G3DSA:1.20.1090.10 158 376 3.0E-81 T 15-10-2018 C2I28_24030 9608e462969b283423e1561009034fa5 316 Pfam PF01032 FecCD transport family 10 311 2.9E-64 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_24030 9608e462969b283423e1561009034fa5 316 Gene3D G3DSA:1.10.3470.10 2 314 1.6E-61 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_24030 9608e462969b283423e1561009034fa5 316 SUPERFAMILY SSF81345 3 312 4.05E-66 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 Pfam PF00106 short chain dehydrogenase 8 195 5.6E-55 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PIRSF PIRSF000126 1 264 2.3E-56 T 15-10-2018 C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 7.6E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 7.6E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 7.6E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.5E-26 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.5E-26 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.5E-26 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.5E-26 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.5E-26 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 SUPERFAMILY SSF51735 4 253 4.0E-63 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03625 9939910ce142e8ef962c9b0d7294600c 264 Gene3D G3DSA:3.40.50.720 1 263 1.1E-66 T 15-10-2018 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 SUPERFAMILY SSF55931 105 442 3.24E-130 T 15-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 5.4E-187 T 15-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.9E-142 T 15-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 SUPERFAMILY SSF54368 5 104 2.35E-34 T 15-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 15-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 SMART SM01230 105 354 4.3E-143 T 15-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 Gene3D G3DSA:3.30.590.10 108 444 1.2E-148 T 15-10-2018 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 15-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 Gene3D G3DSA:3.10.20.70 2 107 1.2E-45 T 15-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 C2I28_02060 c50dc3f067695163c908ceef4aa5f79d 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 2.3E-33 T 15-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 C2I28_24180 819965092b985e3fd5be8e02ca5e4c06 209 PIRSF PIRSF006324 1 209 1.7E-60 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_24180 819965092b985e3fd5be8e02ca5e4c06 209 Pfam PF01810 LysE type translocator 13 207 1.3E-32 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 Pfam PF00005 ABC transporter 379 528 2.5E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 Gene3D G3DSA:1.20.1560.10 15 348 2.9E-88 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 Pfam PF00664 ABC transporter transmembrane region 47 313 5.9E-43 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 SMART SM00382 388 574 3.4E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 SUPERFAMILY SSF90123 32 345 8.63E-75 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 SUPERFAMILY SSF52540 355 597 1.28E-89 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14730 d2f8ca0add73d73f6f487033e0257691 601 Gene3D G3DSA:3.40.50.300 359 601 1.7E-89 T 15-10-2018 C2I28_22170 bb2db0379f8cedfdfc739d181d3a2d08 275 SUPERFAMILY SSF161098 9 275 2.62E-70 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_22170 bb2db0379f8cedfdfc739d181d3a2d08 275 Gene3D G3DSA:1.10.3720.10 2 263 7.2E-61 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_22170 bb2db0379f8cedfdfc739d181d3a2d08 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 270 2.4E-23 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 12 487 4.1E-189 T 15-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 Pfam PF00171 Aldehyde dehydrogenase family 19 483 2.8E-149 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 SUPERFAMILY SSF53720 5 486 5.24E-150 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 Gene3D G3DSA:3.40.309.10 256 456 8.7E-153 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 5 487 69.321 T 15-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 C2I28_03655 d9aa3fbf132da3368442f322e8a229d2 489 Gene3D G3DSA:3.40.605.10 28 464 8.7E-153 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_17860 891bac7e892e86aa3ae451307878116c 295 SUPERFAMILY SSF47807 179 271 3.29E-24 T 15-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily C2I28_17860 891bac7e892e86aa3ae451307878116c 295 SMART SM00279 181 216 6.1E-14 T 15-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 C2I28_17860 891bac7e892e86aa3ae451307878116c 295 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 177 3.0E-38 T 15-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 C2I28_17860 891bac7e892e86aa3ae451307878116c 295 SUPERFAMILY SSF88723 3 177 2.94E-37 T 15-10-2018 IPR029060 PIN-like domain superfamily C2I28_17860 891bac7e892e86aa3ae451307878116c 295 Gene3D G3DSA:1.10.150.20 182 257 2.5E-71 T 15-10-2018 C2I28_17860 891bac7e892e86aa3ae451307878116c 295 Gene3D G3DSA:3.40.50.1010 5 288 2.5E-71 T 15-10-2018 C2I28_17860 891bac7e892e86aa3ae451307878116c 295 SMART SM00475 1 274 8.3E-67 T 15-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 C2I28_17860 891bac7e892e86aa3ae451307878116c 295 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 261 1.7E-26 T 15-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 C2I28_01715 9ecc233cab33dce408e903e8bcd000bd 277 SUPERFAMILY SSF56112 24 248 1.33E-49 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_01715 9ecc233cab33dce408e903e8bcd000bd 277 Pfam PF00069 Protein kinase domain 28 264 8.5E-34 T 15-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I28_01715 9ecc233cab33dce408e903e8bcd000bd 277 SMART SM00219 28 253 1.5E-6 T 15-10-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 C2I28_01715 9ecc233cab33dce408e903e8bcd000bd 277 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 34 57 - T 15-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 C2I28_01715 9ecc233cab33dce408e903e8bcd000bd 277 Gene3D G3DSA:1.10.510.10 19 271 1.7E-45 T 15-10-2018 C2I28_05210 6d859e09682ec928344c1b693b5088d5 257 SMART SM00893 21 211 1.9E-64 T 15-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I28_05210 6d859e09682ec928344c1b693b5088d5 257 SUPERFAMILY SSF52402 1 251 2.41E-78 T 15-10-2018 C2I28_05210 6d859e09682ec928344c1b693b5088d5 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 15-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 C2I28_05210 6d859e09682ec928344c1b693b5088d5 257 Gene3D G3DSA:3.40.50.620 1 256 3.6E-86 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05210 6d859e09682ec928344c1b693b5088d5 257 PIRSF PIRSF000090 1 257 7.9E-79 T 15-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 C2I28_05210 6d859e09682ec928344c1b693b5088d5 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 3.4E-53 T 15-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 Pfam PF00664 ABC transporter transmembrane region 25 292 1.1E-48 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 SUPERFAMILY SSF90123 12 320 3.14E-71 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 SUPERFAMILY SSF52540 330 571 6.46E-88 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 Gene3D G3DSA:1.20.1560.10 2 321 1.7E-80 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 Gene3D G3DSA:3.40.50.300 322 572 1.3E-89 T 15-10-2018 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 Pfam PF00005 ABC transporter 350 500 8.1E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_23040 ae05f0e5a8abf0bef0fd763b14a10343 575 SMART SM00382 359 546 4.1E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_06995 633765cbaa4eda4814bcc25eec4c4df0 304 Gene3D G3DSA:3.20.20.530 18 304 2.7E-96 T 15-10-2018 C2I28_06995 633765cbaa4eda4814bcc25eec4c4df0 304 PIRSF PIRSF000196 1 304 4.6E-127 T 15-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 C2I28_06995 633765cbaa4eda4814bcc25eec4c4df0 304 SUPERFAMILY SSF51730 37 300 1.1E-74 T 15-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I28_06995 633765cbaa4eda4814bcc25eec4c4df0 304 Pfam PF01619 Proline dehydrogenase 44 297 1.9E-37 T 15-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 C2I28_17760 228b75ace5906652455084d55ed6da63 294 Gene3D G3DSA:3.20.20.370 54 286 4.2E-51 T 15-10-2018 C2I28_17760 228b75ace5906652455084d55ed6da63 294 Pfam PF01522 Polysaccharide deacetylase 90 193 2.9E-28 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_17760 228b75ace5906652455084d55ed6da63 294 SUPERFAMILY SSF88713 92 285 5.56E-46 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_20285 97784db251195fabee7d597f3cafc11a 526 SUPERFAMILY SSF56801 13 524 2.62E-144 T 15-10-2018 C2I28_20285 97784db251195fabee7d597f3cafc11a 526 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_20285 97784db251195fabee7d597f3cafc11a 526 Gene3D G3DSA:3.30.300.310 420 526 1.0E-29 T 15-10-2018 C2I28_20285 97784db251195fabee7d597f3cafc11a 526 Gene3D G3DSA:3.40.50.12780 5 417 1.4E-110 T 15-10-2018 C2I28_20285 97784db251195fabee7d597f3cafc11a 526 Pfam PF00501 AMP-binding enzyme 19 424 5.5E-84 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_20285 97784db251195fabee7d597f3cafc11a 526 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 512 1.2E-21 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_06545 73523d3b5264c346063708cb7ad560ca 278 Pfam PF03180 NLPA lipoprotein 33 276 5.6E-80 T 15-10-2018 IPR004872 Lipoprotein NlpA family C2I28_06545 73523d3b5264c346063708cb7ad560ca 278 SUPERFAMILY SSF53850 32 277 2.32E-76 T 15-10-2018 C2I28_06545 73523d3b5264c346063708cb7ad560ca 278 Gene3D G3DSA:3.40.190.10 118 226 4.6E-92 T 15-10-2018 C2I28_06545 73523d3b5264c346063708cb7ad560ca 278 Gene3D G3DSA:3.40.190.10 35 273 4.6E-92 T 15-10-2018 C2I28_06545 73523d3b5264c346063708cb7ad560ca 278 PIRSF PIRSF002854 1 278 1.8E-97 T 15-10-2018 IPR004872 Lipoprotein NlpA family C2I28_06885 5e68ee4d9948ff25fc9079b1e42d91ed 152 SUPERFAMILY SSF55811 3 128 1.18E-27 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_06885 5e68ee4d9948ff25fc9079b1e42d91ed 152 Gene3D G3DSA:3.90.79.10 1 152 4.1E-42 T 15-10-2018 C2I28_06885 5e68ee4d9948ff25fc9079b1e42d91ed 152 Pfam PF00293 NUDIX domain 3 123 2.7E-17 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_06885 5e68ee4d9948ff25fc9079b1e42d91ed 152 PRINTS PR00502 NUDIX hydrolase family signature 40 55 5.7E-6 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_06885 5e68ee4d9948ff25fc9079b1e42d91ed 152 PRINTS PR00502 NUDIX hydrolase family signature 26 40 5.7E-6 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_12980 e44fa21010e20bdd519ce5db4541c2ca 216 Pfam PF03006 Haemolysin-III related 8 204 6.1E-40 T 15-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 C2I28_12980 e44fa21010e20bdd519ce5db4541c2ca 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 11 211 1.3E-65 T 15-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 C2I28_09035 f01807e3d16fafafac83bcecfba01066 178 SUPERFAMILY SSF141523 34 159 3.53E-33 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_09035 f01807e3d16fafafac83bcecfba01066 178 Gene3D G3DSA:2.40.440.10 17 173 1.7E-43 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_09035 f01807e3d16fafafac83bcecfba01066 178 Pfam PF03734 L,D-transpeptidase catalytic domain 36 159 2.9E-25 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_06620 205008c806b103575f0db34fd9c883df 277 Pfam PF00005 ABC transporter 22 169 1.5E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_06620 205008c806b103575f0db34fd9c883df 277 SUPERFAMILY SSF52540 6 231 1.74E-63 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06620 205008c806b103575f0db34fd9c883df 277 Gene3D G3DSA:3.40.50.300 5 251 6.2E-69 T 15-10-2018 C2I28_06620 205008c806b103575f0db34fd9c883df 277 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_06620 205008c806b103575f0db34fd9c883df 277 SMART SM00382 30 218 4.6E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 Gene3D G3DSA:3.40.50.720 1 261 4.3E-88 T 15-10-2018 C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.1E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 SUPERFAMILY SSF51735 6 252 1.46E-82 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 3.5E-64 T 15-10-2018 C2I28_12370 0c25560f02bc02f531f0a636ece57840 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_14855 1403a92386ad6aeab2f9eb728fed6786 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 8.1E-32 T 15-10-2018 IPR019241 Protein of unknown function DUF2197 C2I28_08980 75019c5871d03ab3ce22fbcafe8a1557 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 5.2E-43 T 15-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal C2I28_08980 75019c5871d03ab3ce22fbcafe8a1557 273 PIRSF PIRSF004793 5 269 1.9E-97 T 15-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 C2I28_08980 75019c5871d03ab3ce22fbcafe8a1557 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 254 34.514 T 15-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 C2I28_08980 75019c5871d03ab3ce22fbcafe8a1557 273 Gene3D G3DSA:3.40.1700.10 102 255 1.3E-61 T 15-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I28_08980 75019c5871d03ab3ce22fbcafe8a1557 273 SUPERFAMILY SSF143597 40 240 4.32E-71 T 15-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I28_08980 75019c5871d03ab3ce22fbcafe8a1557 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 4 255 8.4E-102 T 15-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 C2I28_18105 3a75429667bff580d31d1f5d5f32f231 447 Pfam PF03390 2-hydroxycarboxylate transporter family 30 440 2.4E-159 T 15-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 C2I28_18105 3a75429667bff580d31d1f5d5f32f231 447 PIRSF PIRSF005348 10 446 2.8E-172 T 15-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 C2I28_03615 fd51ee8ae0e73dd0eeb9c2292d84be4f 112 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 105 1.3E-27 T 15-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I28_03615 fd51ee8ae0e73dd0eeb9c2292d84be4f 112 Gene3D G3DSA:2.60.300.12 1 111 5.1E-9 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_03615 fd51ee8ae0e73dd0eeb9c2292d84be4f 112 SUPERFAMILY SSF89360 1 106 4.71E-28 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 Gene3D G3DSA:2.30.40.10 9 413 1.0E-176 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 TIGRFAM TIGR01224 hutI: imidazolonepropionase 33 414 3.0E-157 T 15-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 Gene3D G3DSA:3.20.20.140 78 375 1.0E-176 T 15-10-2018 C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 SUPERFAMILY SSF51556 77 376 1.71E-82 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 415 43.765 T 15-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 SUPERFAMILY SSF51338 31 418 2.43E-22 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_16010 c57bf8193d3237f19b9a8f7660845d8a 429 Pfam PF01979 Amidohydrolase family 74 415 2.2E-21 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 Gene3D G3DSA:3.40.50.300 251 496 6.0E-46 T 15-10-2018 C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 Pfam PF00005 ABC transporter 21 169 4.3E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 SUPERFAMILY SSF52540 4 227 1.3E-61 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 SMART SM00382 29 217 2.3E-9 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 SMART SM00382 281 477 1.1 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 Gene3D G3DSA:3.40.50.300 2 237 9.1E-61 T 15-10-2018 C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 Pfam PF00005 ABC transporter 272 428 1.5E-19 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_00585 b5624e1a89b8abd0df24b3c0aaf3e48f 510 SUPERFAMILY SSF52540 256 489 4.11E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 SMART SM00490 565 662 2.1E-10 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 SUPERFAMILY SSF52540 234 448 9.55E-44 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 SUPERFAMILY SSF52540 533 707 3.09E-37 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 Gene3D G3DSA:1.10.8.630 2 113 3.7E-25 T 15-10-2018 C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 Gene3D G3DSA:3.40.50.300 253 449 3.7E-77 T 15-10-2018 C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 SMART SM00487 263 462 1.4E-27 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 Pfam PF00270 DEAD/DEAH box helicase 268 432 6.0E-19 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 803 25.457 T 15-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 TIGRFAM TIGR00595 priA: primosomal protein N' 291 801 4.0E-220 T 15-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 C2I28_02775 320924fbc1ad23e1edcef38220fd66fd 804 Pfam PF00271 Helicase conserved C-terminal domain 573 661 4.2E-8 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 ProSitePatterns PS00502 Polygalacturonase active site. 279 293 - T 15-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 Pfam PF12708 Pectate lyase superfamily protein 18 73 3.4E-13 T 15-10-2018 IPR024535 Pectate lyase superfamily protein C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SUPERFAMILY SSF51126 9 406 5.24E-101 T 15-10-2018 IPR011050 Pectin lyase fold/virulence factor C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 Pfam PF00295 Glycosyl hydrolases family 28 181 360 1.1E-29 T 15-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SMART SM00710 366 387 800.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SMART SM00710 272 293 4.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SMART SM00710 393 414 5300.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SMART SM00710 213 237 1000.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SMART SM00710 325 347 3600.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 SMART SM00710 238 259 5.0 T 15-10-2018 IPR006626 Parallel beta-helix repeat C2I28_17455 d42a19bbfabb7fca7591aefaca469d27 434 Gene3D G3DSA:2.160.20.10 1 433 1.4E-152 T 15-10-2018 IPR012334 Pectin lyase fold C2I28_21555 8c811a58b5f12876246612191717b024 157 PIRSF PIRSF008757 2 157 3.0E-51 T 15-10-2018 IPR010371 Uncharacterised protein family UPF0303 C2I28_21555 8c811a58b5f12876246612191717b024 157 SUPERFAMILY SSF143744 16 155 3.27E-27 T 15-10-2018 IPR038084 GlcG-like domain superfamily C2I28_21555 8c811a58b5f12876246612191717b024 157 Pfam PF03928 Haem-degrading 25 151 3.3E-35 T 15-10-2018 IPR005624 Haem-degrading C2I28_21555 8c811a58b5f12876246612191717b024 157 Gene3D G3DSA:3.30.450.150 2 157 4.5E-53 T 15-10-2018 IPR038084 GlcG-like domain superfamily C2I28_02860 6d1942d0856feef8264e247b01b3161f 180 Gene3D G3DSA:3.40.50.2020 2 180 6.0E-62 T 15-10-2018 C2I28_02860 6d1942d0856feef8264e247b01b3161f 180 SUPERFAMILY SSF53271 6 174 8.78E-44 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_02860 6d1942d0856feef8264e247b01b3161f 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 39.372 T 15-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 C2I28_02860 6d1942d0856feef8264e247b01b3161f 180 Pfam PF00156 Phosphoribosyl transferase domain 6 152 1.5E-24 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_23375 939579ee43f7d625bac8050f148ecf64 389 Pfam PF07690 Major Facilitator Superfamily 10 337 3.8E-15 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_23375 939579ee43f7d625bac8050f148ecf64 389 SUPERFAMILY SSF103473 2 384 1.29E-31 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_23375 939579ee43f7d625bac8050f148ecf64 389 Gene3D G3DSA:1.20.1250.20 1 381 1.1E-25 T 15-10-2018 C2I28_14025 3db6bba0138a8545bd57408fe8189e33 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 5.6E-17 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_14025 3db6bba0138a8545bd57408fe8189e33 132 SUPERFAMILY SSF54593 1 127 3.36E-30 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_14025 3db6bba0138a8545bd57408fe8189e33 132 Gene3D G3DSA:3.10.180.10 8 127 2.2E-31 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 Gene3D G3DSA:3.30.70.270 334 501 7.3E-43 T 15-10-2018 C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 SUPERFAMILY SSF55785 215 330 2.0E-5 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 Pfam PF00990 Diguanylate cyclase, GGDEF domain 343 497 4.8E-36 T 15-10-2018 IPR000160 GGDEF domain C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 SUPERFAMILY SSF55073 348 496 2.35E-37 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 Gene3D G3DSA:3.30.450.20 213 333 2.4E-6 T 15-10-2018 C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 SMART SM00267 332 503 9.8E-37 T 15-10-2018 IPR000160 GGDEF domain C2I28_15155 8ad4eeceb61953dac6e26633aa2d4008 503 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 341 496 1.2E-34 T 15-10-2018 IPR000160 GGDEF domain C2I28_15800 e0ad1a6ce603222d7196bda4821dc87c 154 Pfam PF09021 HutP 14 152 3.8E-31 T 15-10-2018 IPR015111 Hut operon regulatory protein HutP C2I28_15800 e0ad1a6ce603222d7196bda4821dc87c 154 Gene3D G3DSA:3.40.1510.10 5 154 1.4E-61 T 15-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily C2I28_15800 e0ad1a6ce603222d7196bda4821dc87c 154 SUPERFAMILY SSF111064 14 154 2.88E-41 T 15-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily C2I28_25575 a6ce7f4e2d372a49fb254e207ead84d2 232 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 195 2.3E-45 T 15-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I28_25575 a6ce7f4e2d372a49fb254e207ead84d2 232 SUPERFAMILY SSF53639 3 222 1.0E-67 T 15-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I28_25575 a6ce7f4e2d372a49fb254e207ead84d2 232 Gene3D G3DSA:3.40.225.10 1 230 7.1E-61 T 15-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I28_25575 a6ce7f4e2d372a49fb254e207ead84d2 232 SMART SM01007 7 197 4.4E-65 T 15-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 488 2.1E-113 T 15-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 179 185 - T 15-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 Gene3D G3DSA:3.40.50.720 4 177 2.8E-64 T 15-10-2018 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 7 490 86.995 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 SUPERFAMILY SSF51735 6 192 1.63E-63 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 Gene3D G3DSA:3.30.360.10 178 490 2.0E-122 T 15-10-2018 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 11 189 2.9E-65 T 15-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 3.7E-46 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 3.7E-46 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 3.7E-46 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 3.7E-46 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 3.7E-46 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 PIRSF PIRSF000110 1 492 1.5E-187 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 7 489 1.6E-200 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_07625 0902da33caedbbcc557272ef56c978e1 500 SUPERFAMILY SSF55347 184 489 3.6E-112 T 15-10-2018 C2I28_11825 ddf553844f383fe6ea35ca8847826f5e 297 Gene3D G3DSA:3.30.2350.10 84 296 2.0E-62 T 15-10-2018 C2I28_11825 ddf553844f383fe6ea35ca8847826f5e 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 39 293 4.3E-68 T 15-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_11825 ddf553844f383fe6ea35ca8847826f5e 297 Pfam PF00849 RNA pseudouridylate synthase 92 240 1.5E-28 T 15-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_11825 ddf553844f383fe6ea35ca8847826f5e 297 SUPERFAMILY SSF55120 76 293 7.04E-67 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_11825 ddf553844f383fe6ea35ca8847826f5e 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 15-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_10270 b91f2d51fcb6548ba679da7f2e476afb 309 Gene3D G3DSA:1.10.150.130 15 120 1.5E-15 T 15-10-2018 IPR010998 Integrase/recombinase, N-terminal C2I28_10270 b91f2d51fcb6548ba679da7f2e476afb 309 SUPERFAMILY SSF56349 22 294 1.32E-51 T 15-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 C2I28_10270 b91f2d51fcb6548ba679da7f2e476afb 309 Gene3D G3DSA:1.10.443.10 121 306 3.0E-39 T 15-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 C2I28_10270 b91f2d51fcb6548ba679da7f2e476afb 309 Pfam PF00589 Phage integrase family 124 288 4.9E-32 T 15-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 C2I28_10270 b91f2d51fcb6548ba679da7f2e476afb 309 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 25 102 7.7E-10 T 15-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 C2I28_10770 d1c498c33f63ce74ab24b26ea82ef705 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 15-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_10770 d1c498c33f63ce74ab24b26ea82ef705 303 Gene3D G3DSA:3.30.2350.10 74 290 6.8E-66 T 15-10-2018 C2I28_10770 d1c498c33f63ce74ab24b26ea82ef705 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 293 3.0E-71 T 15-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_10770 d1c498c33f63ce74ab24b26ea82ef705 303 SUPERFAMILY SSF55120 75 292 1.04E-66 T 15-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_10770 d1c498c33f63ce74ab24b26ea82ef705 303 Pfam PF00849 RNA pseudouridylate synthase 91 244 2.4E-34 T 15-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 C2I28_18225 e7ace1fd08f3c09b804e7acf924aa162 463 PIRSF PIRSF026631 1 444 1.4E-86 T 15-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 C2I28_18225 e7ace1fd08f3c09b804e7acf924aa162 463 Pfam PF03703 Bacterial PH domain 61 141 1.3E-17 T 15-10-2018 IPR005182 Domain of unknown function DUF304 C2I28_18225 e7ace1fd08f3c09b804e7acf924aa162 463 Pfam PF03703 Bacterial PH domain 240 309 1.1E-10 T 15-10-2018 IPR005182 Domain of unknown function DUF304 C2I28_18225 e7ace1fd08f3c09b804e7acf924aa162 463 Pfam PF03703 Bacterial PH domain 387 438 1.6E-4 T 15-10-2018 IPR005182 Domain of unknown function DUF304 C2I28_22115 4d54c5a1609cec6ce9feed62609e43b3 262 Pfam PF13395 HNH endonuclease 163 212 2.0E-15 T 15-10-2018 IPR003615 HNH nuclease C2I28_22115 4d54c5a1609cec6ce9feed62609e43b3 262 Gene3D G3DSA:3.30.40.60 124 235 9.3E-14 T 15-10-2018 C2I28_22115 4d54c5a1609cec6ce9feed62609e43b3 262 SMART SM00507 150 205 6.4E-6 T 15-10-2018 IPR003615 HNH nuclease C2I28_08440 675f75548d932b99666ae2816050edea 246 Pfam PF00092 von Willebrand factor type A domain 3 80 7.1E-7 T 15-10-2018 IPR002035 von Willebrand factor, type A C2I28_08440 675f75548d932b99666ae2816050edea 246 SUPERFAMILY SSF53300 134 226 1.31E-10 T 15-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I28_08440 675f75548d932b99666ae2816050edea 246 Gene3D G3DSA:3.40.50.410 1 239 8.9E-58 T 15-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I28_08440 675f75548d932b99666ae2816050edea 246 SUPERFAMILY SSF53300 3 84 5.19E-9 T 15-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I28_08440 675f75548d932b99666ae2816050edea 246 Pfam PF13519 von Willebrand factor type A domain 136 235 5.0E-6 T 15-10-2018 IPR002035 von Willebrand factor, type A C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 SUPERFAMILY SSF51011 395 482 2.73E-35 T 15-10-2018 C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 PIRSF PIRSF001021 1 483 6.6E-221 T 15-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 Gene3D G3DSA:3.20.20.80 6 372 7.5E-160 T 15-10-2018 C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 Gene3D G3DSA:2.40.30.140 104 207 7.5E-160 T 15-10-2018 C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 Pfam PF00128 Alpha amylase, catalytic domain 32 373 3.1E-32 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 SMART SM00642 5 391 1.2E-67 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 SUPERFAMILY SSF51445 6 375 3.19E-102 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_07785 bf433c9726d3d0c2b596e220e68fbe04 483 Gene3D G3DSA:2.60.40.1180 397 483 7.4E-35 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 15-10-2018 IPR033135 ClpP, histidine active site C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 SUPERFAMILY SSF52096 11 190 1.08E-69 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 Pfam PF00574 Clp protease 13 190 3.9E-83 T 15-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 6.0E-51 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 6.0E-51 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 6.0E-51 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 6.0E-51 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 6.0E-51 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 43.34 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 190 1.8E-99 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_00655 96a8ff4795c2ab55fa41c052b490c4f4 193 Gene3D G3DSA:3.90.226.10 1 192 1.4E-79 T 15-10-2018 C2I28_25680 ec84c58b47aa192649f05abd23ff7a99 117 Pfam PF13789 Domain of unknown function (DUF4181) 13 112 3.4E-13 T 15-10-2018 IPR025441 Protein of unknown function DUF4181 C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 SMART SM00116 212 260 6.9E-9 T 15-10-2018 IPR000644 CBS domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 SMART SM00116 148 201 0.046 T 15-10-2018 IPR000644 CBS domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 SUPERFAMILY SSF54631 140 279 1.26E-35 T 15-10-2018 C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Gene3D G3DSA:3.10.580.10 137 265 6.9E-50 T 15-10-2018 C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Gene3D G3DSA:1.10.357.20 279 455 5.0E-60 T 15-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Pfam PF01769 Divalent cation transporter 326 447 4.0E-32 T 15-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Gene3D G3DSA:1.25.60.10 4 136 1.5E-42 T 15-10-2018 IPR038076 MgtE, N-terminal domain superfamily C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 SUPERFAMILY SSF158791 13 138 1.02E-31 T 15-10-2018 C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 SMART SM00924 36 141 4.0E-27 T 15-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 SUPERFAMILY SSF161093 285 454 4.05E-53 T 15-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Pfam PF03448 MgtE intracellular N domain 36 138 8.7E-25 T 15-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Pfam PF00571 CBS domain 205 260 1.3E-9 T 15-10-2018 IPR000644 CBS domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 Pfam PF00571 CBS domain 141 199 7.9E-10 T 15-10-2018 IPR000644 CBS domain C2I28_11835 4b758ff700ddad464f3675481dced1d4 458 TIGRFAM TIGR00400 mgtE: magnesium transporter 19 455 2.5E-136 T 15-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 C2I28_25440 ee494a864985d2cf8ac2f4ad1b193330 519 Pfam PF00474 Sodium:solute symporter family 38 430 4.0E-24 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_25440 ee494a864985d2cf8ac2f4ad1b193330 519 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 38 430 2.5E-61 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_25440 ee494a864985d2cf8ac2f4ad1b193330 519 Gene3D G3DSA:1.20.1730.10 27 496 1.6E-62 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 SUPERFAMILY SSF51735 5 251 5.75E-87 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.7E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.7E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.7E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.7E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-40 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 2.4E-69 T 15-10-2018 C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.0E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.0E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.0E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16185 e7ca913a3bf4e8289020eae928e2fe68 252 Gene3D G3DSA:3.40.50.720 1 250 1.1E-87 T 15-10-2018 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Gene3D G3DSA:3.30.565.10 387 532 4.2E-25 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 SUPERFAMILY SSF55890 327 426 9.81E-14 T 15-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Gene3D G3DSA:1.10.287.130 315 378 2.3E-6 T 15-10-2018 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Gene3D G3DSA:3.30.450.20 36 176 3.6E-36 T 15-10-2018 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 SMART SM00387 421 529 3.0E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 323 372 6.4E-11 T 15-10-2018 IPR039506 SpoOB, alpha-helical domain C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Pfam PF17203 Single cache domain 3 49 173 2.0E-17 T 15-10-2018 IPR033463 Single cache domain 3 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 SUPERFAMILY SSF55874 399 526 1.31E-25 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 3.7E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 526 3.7E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 3.7E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 527 4.0E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 SUPERFAMILY SSF103190 41 174 3.66E-30 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_19730 8699a5b12c549854bf1ec8a6bd1ca380 537 Gene3D G3DSA:3.30.450.20 204 314 1.9E-11 T 15-10-2018 C2I28_21995 84d569fe9dc0ef5142cd0591760b84f4 378 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 1.5E-166 T 15-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 C2I28_21995 84d569fe9dc0ef5142cd0591760b84f4 378 PIRSF PIRSF006078 1 376 1.2E-146 T 15-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 C2I28_21995 84d569fe9dc0ef5142cd0591760b84f4 378 Gene3D G3DSA:3.90.1510.10 42 276 2.7E-146 T 15-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 C2I28_21995 84d569fe9dc0ef5142cd0591760b84f4 378 Gene3D G3DSA:3.40.50.10350 1 362 2.7E-146 T 15-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold C2I28_21995 84d569fe9dc0ef5142cd0591760b84f4 378 SUPERFAMILY SSF110738 1 375 7.98E-147 T 15-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 C2I28_21995 84d569fe9dc0ef5142cd0591760b84f4 378 Pfam PF02595 Glycerate kinase family 3 373 2.2E-155 T 15-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 10 258 3.0E-98 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PIRSF PIRSF000513 4 268 5.3E-100 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 Pfam PF02110 Hydroxyethylthiazole kinase family 10 255 1.8E-95 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 260 33.884 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 2.4E-43 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 2.4E-43 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 2.4E-43 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 2.4E-43 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 2.4E-43 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 2.4E-43 T 15-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 Gene3D G3DSA:3.40.1190.20 1 268 1.2E-102 T 15-10-2018 IPR029056 Ribokinase-like C2I28_18620 f76ba7303f8f69d7d240f81549339894 268 SUPERFAMILY SSF53613 6 265 4.37E-64 T 15-10-2018 IPR029056 Ribokinase-like C2I28_26845 0f9277a22ab806add43ab2fe919fb3e3 283 SUPERFAMILY SSF46689 1 78 2.69E-20 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_26845 0f9277a22ab806add43ab2fe919fb3e3 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 75 2.4E-14 T 15-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I28_26845 0f9277a22ab806add43ab2fe919fb3e3 283 SUPERFAMILY SSF53697 106 278 1.85E-29 T 15-10-2018 C2I28_26845 0f9277a22ab806add43ab2fe919fb3e3 283 Gene3D G3DSA:1.10.10.10 1 78 1.6E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26845 0f9277a22ab806add43ab2fe919fb3e3 283 Gene3D G3DSA:3.40.50.10490 95 278 3.6E-38 T 15-10-2018 C2I28_26845 0f9277a22ab806add43ab2fe919fb3e3 283 Pfam PF01380 SIS domain 129 253 1.5E-21 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_01185 8db2413f4c26984f380d5f28a3d4e5c7 172 Gene3D G3DSA:3.40.50.360 1 172 4.9E-57 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_01185 8db2413f4c26984f380d5f28a3d4e5c7 172 Pfam PF02525 Flavodoxin-like fold 1 170 1.7E-49 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_01185 8db2413f4c26984f380d5f28a3d4e5c7 172 SUPERFAMILY SSF52218 1 172 2.43E-50 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 1.2E-36 T 15-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 Gene3D G3DSA:3.30.390.30 348 468 9.4E-44 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 4.3E-42 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 4.3E-42 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 4.3E-42 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 4.3E-42 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 4.3E-42 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 Gene3D G3DSA:3.50.50.60 13 335 2.6E-125 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 2.3E-176 T 15-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PIRSF PIRSF000350 3 458 8.2E-98 T 15-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 3.7E-74 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 SUPERFAMILY SSF51905 7 340 6.22E-67 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 15-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 SUPERFAMILY SSF55424 346 468 2.06E-40 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 3.6E-77 T 15-10-2018 C2I28_14785 d18810d492229b152edb0a2f10dc51e7 470 Gene3D G3DSA:3.50.50.60 152 273 2.6E-125 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 Gene3D G3DSA:3.40.430.10 1 161 6.7E-65 T 15-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 SUPERFAMILY SSF53597 1 160 1.14E-61 T 15-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.3E-16 T 15-10-2018 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.3E-16 T 15-10-2018 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.3E-16 T 15-10-2018 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.3E-16 T 15-10-2018 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 15-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 Pfam PF00186 Dihydrofolate reductase 1 160 1.9E-67 T 15-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 C2I28_01855 353b72bc1df846d7ced87b4ba2b6ad12 161 PIRSF PIRSF000194 1 161 1.3E-64 T 15-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 C2I28_04435 780a11c108474d16de8d06dd9b7d8655 188 PIRSF PIRSF006019 1 151 1.1E-59 T 15-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 C2I28_04435 780a11c108474d16de8d06dd9b7d8655 188 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.5E-28 T 15-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I28_04435 780a11c108474d16de8d06dd9b7d8655 188 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 150 1.1E-86 T 15-10-2018 IPR013404 Competence operon E, ComEB C2I28_04435 780a11c108474d16de8d06dd9b7d8655 188 SUPERFAMILY SSF53927 7 139 1.17E-40 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_04435 780a11c108474d16de8d06dd9b7d8655 188 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 15-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I28_04435 780a11c108474d16de8d06dd9b7d8655 188 Gene3D G3DSA:3.40.140.10 2 149 3.4E-47 T 15-10-2018 C2I28_27295 d07b5ad7eab092c0f3b05c692172479c 191 Gene3D G3DSA:1.10.1660.10 2 117 1.8E-15 T 15-10-2018 C2I28_27295 d07b5ad7eab092c0f3b05c692172479c 191 Pfam PF13152 Protein of unknown function (DUF3967) 149 175 1.2E-8 T 15-10-2018 IPR025052 Domain of unknown function DUF3967 C2I28_27295 d07b5ad7eab092c0f3b05c692172479c 191 SUPERFAMILY SSF46955 11 107 8.7E-15 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_27295 d07b5ad7eab092c0f3b05c692172479c 191 Pfam PF13411 MerR HTH family regulatory protein 11 79 1.5E-13 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27295 d07b5ad7eab092c0f3b05c692172479c 191 SMART SM00422 11 80 0.0054 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27695 d07b5ad7eab092c0f3b05c692172479c 191 Gene3D G3DSA:1.10.1660.10 2 117 1.8E-15 T 15-10-2018 C2I28_27695 d07b5ad7eab092c0f3b05c692172479c 191 Pfam PF13152 Protein of unknown function (DUF3967) 149 175 1.2E-8 T 15-10-2018 IPR025052 Domain of unknown function DUF3967 C2I28_27695 d07b5ad7eab092c0f3b05c692172479c 191 SUPERFAMILY SSF46955 11 107 8.7E-15 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_27695 d07b5ad7eab092c0f3b05c692172479c 191 Pfam PF13411 MerR HTH family regulatory protein 11 79 1.5E-13 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_27695 d07b5ad7eab092c0f3b05c692172479c 191 SMART SM00422 11 80 0.0054 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_21780 2010bbe4629cba16f0a3111b03b70494 302 SUPERFAMILY SSF56112 18 265 3.76E-32 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_21780 2010bbe4629cba16f0a3111b03b70494 302 Gene3D G3DSA:3.30.200.20 15 103 7.2E-30 T 15-10-2018 C2I28_21780 2010bbe4629cba16f0a3111b03b70494 302 Pfam PF01636 Phosphotransferase enzyme family 33 262 1.1E-30 T 15-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I28_21780 2010bbe4629cba16f0a3111b03b70494 302 Gene3D G3DSA:3.90.1200.10 106 300 1.9E-33 T 15-10-2018 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Gene3D G3DSA:3.90.105.10 26 183 3.2E-117 T 15-10-2018 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 4.0E-33 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Gene3D G3DSA:2.40.340.10 338 406 3.2E-117 T 15-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Gene3D G3DSA:3.40.980.10 184 337 3.2E-117 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 SUPERFAMILY SSF53218 186 331 6.94E-39 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 SMART SM00852 189 327 1.4E-36 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 SUPERFAMILY SSF63882 8 185 6.15E-50 T 15-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Gene3D G3DSA:2.170.190.11 50 150 3.2E-117 T 15-10-2018 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Pfam PF03454 MoeA C-terminal region (domain IV) 340 411 2.6E-13 T 15-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 SUPERFAMILY SSF63867 338 413 3.01E-15 T 15-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Pfam PF00994 Probable molybdopterin binding domain 190 325 1.8E-26 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_06735 5e2f03403d0a1e2dc48c2f8647f1afbc 421 Pfam PF03453 MoeA N-terminal region (domain I and II) 13 176 1.6E-38 T 15-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 C2I28_01355 50fd42abb9fe87c0c2908a4a65e51304 249 Pfam PF01925 Sulfite exporter TauE/SafE 6 243 1.0E-39 T 15-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I28_18135 d8ed7e7556a38aab7793359a4b70f373 273 Gene3D G3DSA:3.40.190.10 41 263 3.4E-80 T 15-10-2018 C2I28_18135 d8ed7e7556a38aab7793359a4b70f373 273 SMART SM00062 38 265 9.2E-66 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_18135 d8ed7e7556a38aab7793359a4b70f373 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 264 2.2E-53 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_18135 d8ed7e7556a38aab7793359a4b70f373 273 Gene3D G3DSA:3.40.190.10 107 227 3.4E-80 T 15-10-2018 C2I28_18135 d8ed7e7556a38aab7793359a4b70f373 273 SUPERFAMILY SSF53850 1 265 7.22E-53 T 15-10-2018 C2I28_19075 b3e12a0dbd9dbe4e61253fcae26db8cb 336 SUPERFAMILY SSF51679 2 328 1.07E-68 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_19075 b3e12a0dbd9dbe4e61253fcae26db8cb 336 Pfam PF00296 Luciferase-like monooxygenase 10 299 1.1E-34 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_19075 b3e12a0dbd9dbe4e61253fcae26db8cb 336 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 328 1.1E-118 T 15-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 C2I28_19075 b3e12a0dbd9dbe4e61253fcae26db8cb 336 Gene3D G3DSA:3.20.20.30 1 332 1.1E-96 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 15-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 251 8.0E-89 T 15-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 494 3.4E-228 T 15-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 Gene3D G3DSA:3.30.420.40 253 496 8.2E-95 T 15-10-2018 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 PIRSF PIRSF000538 2 495 4.4E-180 T 15-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 SUPERFAMILY SSF53067 4 254 3.02E-96 T 15-10-2018 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 15-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.94 T 15-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 1.1E-65 T 15-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 SUPERFAMILY SSF53067 254 493 2.33E-89 T 15-10-2018 C2I28_10815 b0ec1c980f032fb285b229c04c1cc341 496 Gene3D G3DSA:3.30.420.40 1 252 6.1E-112 T 15-10-2018 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 Gene3D G3DSA:3.30.420.150 110 300 3.0E-49 T 15-10-2018 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 Gene3D G3DSA:1.10.3210.10 310 506 6.9E-37 T 15-10-2018 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 Gene3D G3DSA:3.30.420.40 2 109 5.6E-26 T 15-10-2018 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 SUPERFAMILY SSF109604 313 506 3.45E-29 T 15-10-2018 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 SUPERFAMILY SSF53067 5 126 1.4E-29 T 15-10-2018 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 Pfam PF02541 Ppx/GppA phosphatase family 18 302 1.2E-50 T 15-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 C2I28_14635 3fe003396e43fed217a5d35425714aab 508 SUPERFAMILY SSF53067 129 303 3.05E-37 T 15-10-2018 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 SUPERFAMILY SSF53187 178 492 1.07E-111 T 15-10-2018 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 487 1.8E-116 T 15-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 PRINTS PR00481 Cytosol aminopeptidase signature 258 275 2.2E-51 T 15-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 PRINTS PR00481 Cytosol aminopeptidase signature 280 301 2.2E-51 T 15-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 PRINTS PR00481 Cytosol aminopeptidase signature 317 338 2.2E-51 T 15-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 PRINTS PR00481 Cytosol aminopeptidase signature 339 359 2.2E-51 T 15-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 PRINTS PR00481 Cytosol aminopeptidase signature 367 382 2.2E-51 T 15-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 Gene3D G3DSA:3.40.220.10 6 158 2.9E-36 T 15-10-2018 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 18 146 3.5E-21 T 15-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 Gene3D G3DSA:3.40.630.10 169 493 2.4E-125 T 15-10-2018 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 343 350 - T 15-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 496 34.252 T 15-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 C2I28_06360 b9d8c20fdbfecaf78fd3e451db4f3361 497 SUPERFAMILY SSF52949 8 164 5.65E-31 T 15-10-2018 C2I28_14685 867d1274f674872307f63a466e81cba2 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14685 867d1274f674872307f63a466e81cba2 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14685 867d1274f674872307f63a466e81cba2 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14685 867d1274f674872307f63a466e81cba2 292 Pfam PF03466 LysR substrate binding domain 89 287 2.3E-35 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_14685 867d1274f674872307f63a466e81cba2 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 6.5E-16 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14685 867d1274f674872307f63a466e81cba2 292 SUPERFAMILY SSF53850 89 290 5.02E-31 T 15-10-2018 C2I28_14685 867d1274f674872307f63a466e81cba2 292 Gene3D G3DSA:1.10.10.10 1 81 8.6E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14685 867d1274f674872307f63a466e81cba2 292 SUPERFAMILY SSF46785 6 111 1.25E-18 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_14685 867d1274f674872307f63a466e81cba2 292 Gene3D G3DSA:3.40.190.290 82 287 2.9E-66 T 15-10-2018 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 Gene3D G3DSA:3.30.230.10 9 161 2.1E-78 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_06425 b410f1866422e032fbbddacace65e54d 304 Pfam PF08544 GHMP kinases C terminal 204 281 1.5E-11 T 15-10-2018 IPR013750 GHMP kinase, C-terminal domain C2I28_06425 b410f1866422e032fbbddacace65e54d 304 PRINTS PR00958 Homoserine kinase signature 130 143 1.5E-39 T 15-10-2018 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 PRINTS PR00958 Homoserine kinase signature 14 29 1.5E-39 T 15-10-2018 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 PRINTS PR00958 Homoserine kinase signature 96 111 1.5E-39 T 15-10-2018 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 PRINTS PR00958 Homoserine kinase signature 168 185 1.5E-39 T 15-10-2018 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 PRINTS PR00958 Homoserine kinase signature 248 263 1.5E-39 T 15-10-2018 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 Pfam PF00288 GHMP kinases N terminal domain 83 143 5.9E-14 T 15-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 TIGRFAM TIGR00191 thrB: homoserine kinase 7 298 3.7E-89 T 15-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 15-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 Hamap MF_00384 Homoserine kinase [thrB]. 9 298 29.288 T 15-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 PIRSF PIRSF000676 3 300 5.1E-88 T 15-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 C2I28_06425 b410f1866422e032fbbddacace65e54d 304 Gene3D G3DSA:3.30.70.890 162 266 2.1E-78 T 15-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I28_06425 b410f1866422e032fbbddacace65e54d 304 SUPERFAMILY SSF54211 7 151 1.06E-30 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_06425 b410f1866422e032fbbddacace65e54d 304 SUPERFAMILY SSF55060 163 283 4.17E-32 T 15-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I28_01055 b4635bb54969cf06d3a775b31df6c936 540 PIRSF PIRSF005690 23 518 3.4E-193 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_01055 b4635bb54969cf06d3a775b31df6c936 540 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 38 503 1.7E-191 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_23620 c6cd80094ef173c87ae5907c34a65b10 177 Pfam PF00583 Acetyltransferase (GNAT) family 47 151 1.9E-18 T 15-10-2018 IPR000182 GNAT domain C2I28_23620 c6cd80094ef173c87ae5907c34a65b10 177 SUPERFAMILY SSF55729 12 176 4.73E-27 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_23620 c6cd80094ef173c87ae5907c34a65b10 177 Gene3D G3DSA:3.40.630.30 11 177 1.9E-37 T 15-10-2018 C2I28_01810 77430a056f9da28922383d76ec043633 251 Pfam PF14344 Domain of unknown function (DUF4397) 61 174 1.8E-35 T 15-10-2018 IPR025510 Domain of unknown function DUF4397 C2I28_24190 ed358c428c82279142a3c4f4ae5ec665 273 SUPERFAMILY SSF55874 152 263 5.11E-12 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_24190 ed358c428c82279142a3c4f4ae5ec665 273 Pfam PF07730 Histidine kinase 80 140 8.0E-11 T 15-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I28_24190 ed358c428c82279142a3c4f4ae5ec665 273 Gene3D G3DSA:3.30.565.10 146 272 2.1E-19 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_10720 b4bcdc4e0a35c032e1080fc9af36942a 306 TIGRFAM TIGR00688 rarD: protein RarD 8 264 2.7E-74 T 15-10-2018 IPR004626 RarD protein GO:0005887 C2I28_10720 b4bcdc4e0a35c032e1080fc9af36942a 306 SUPERFAMILY SSF103481 42 150 1.06E-11 T 15-10-2018 C2I28_10720 b4bcdc4e0a35c032e1080fc9af36942a 306 SUPERFAMILY SSF103481 195 290 1.57E-9 T 15-10-2018 C2I28_10720 b4bcdc4e0a35c032e1080fc9af36942a 306 Pfam PF00892 EamA-like transporter family 9 148 1.1E-14 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_10720 b4bcdc4e0a35c032e1080fc9af36942a 306 Pfam PF00892 EamA-like transporter family 159 286 6.0E-7 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_21440 d200e579beb8d2a0c0dd8027468ae1f5 331 Gene3D G3DSA:3.20.20.30 1 331 4.3E-104 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_21440 d200e579beb8d2a0c0dd8027468ae1f5 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 327 2.3E-117 T 15-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 C2I28_21440 d200e579beb8d2a0c0dd8027468ae1f5 331 SUPERFAMILY SSF51679 1 328 3.14E-73 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_21440 d200e579beb8d2a0c0dd8027468ae1f5 331 Pfam PF00296 Luciferase-like monooxygenase 2 299 3.3E-41 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_25275 8a48899aac3761a27761e9e8e8fbc68e 243 Gene3D G3DSA:3.30.460.10 1 118 1.2E-10 T 15-10-2018 C2I28_25275 8a48899aac3761a27761e9e8e8fbc68e 243 SUPERFAMILY SSF81301 6 109 5.29E-12 T 15-10-2018 C2I28_25275 8a48899aac3761a27761e9e8e8fbc68e 243 Pfam PF01909 Nucleotidyltransferase domain 28 70 1.6E-4 T 15-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 C2I28_06840 d599838ccf95ce122a61df6dd18c8a23 82 Gene3D G3DSA:3.40.30.10 1 75 1.3E-21 T 15-10-2018 C2I28_06840 d599838ccf95ce122a61df6dd18c8a23 82 SUPERFAMILY SSF52833 3 75 7.7E-18 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_06840 d599838ccf95ce122a61df6dd18c8a23 82 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 62 1.3E-18 T 15-10-2018 IPR008554 Glutaredoxin-like C2I28_14385 49eeed7d2f6da84baf9c26b7afcf720c 293 Gene3D G3DSA:3.40.50.1820 47 293 4.3E-49 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_14385 49eeed7d2f6da84baf9c26b7afcf720c 293 SUPERFAMILY SSF53474 49 290 7.13E-46 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_14385 49eeed7d2f6da84baf9c26b7afcf720c 293 Pfam PF00326 Prolyl oligopeptidase family 97 290 1.2E-28 T 15-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 PIRSF PIRSF001455 3 359 1.2E-108 T 15-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 352 1.3E-118 T 15-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 354 66.092 T 15-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 Gene3D G3DSA:1.20.1090.10 173 358 9.9E-59 T 15-10-2018 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 SUPERFAMILY SSF56796 8 356 8.9E-102 T 15-10-2018 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 Pfam PF01761 3-dehydroquinate synthase 68 324 3.3E-100 T 15-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 C2I28_03195 a654af194e8fb60f89dceddd738517c6 360 Gene3D G3DSA:3.40.50.1970 2 172 5.4E-60 T 15-10-2018 C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 SUPERFAMILY SSF46785 9 140 5.05E-34 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 SMART SM00347 31 131 8.7E-22 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 Gene3D G3DSA:1.10.10.10 1 146 2.2E-37 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 8.4E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 8.4E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 8.4E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_19455 913c40b47e364fe3f73b0c72b8f5cbf3 149 Pfam PF01047 MarR family 39 96 1.8E-15 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12925 7746e56cf435587765450b6f44c94dd9 447 SUPERFAMILY SSF51556 57 363 4.0E-99 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_12925 7746e56cf435587765450b6f44c94dd9 447 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 439 40.176 T 15-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 C2I28_12925 7746e56cf435587765450b6f44c94dd9 447 Gene3D G3DSA:2.30.40.10 11 431 9.6E-144 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_12925 7746e56cf435587765450b6f44c94dd9 447 Pfam PF01979 Amidohydrolase family 54 413 1.8E-78 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_12925 7746e56cf435587765450b6f44c94dd9 447 SUPERFAMILY SSF51338 3 439 8.4E-31 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_12925 7746e56cf435587765450b6f44c94dd9 447 Gene3D G3DSA:3.20.20.140 58 355 9.6E-144 T 15-10-2018 C2I28_12025 39d412406e2bd3e0df675fa4ebeaa637 192 Gene3D G3DSA:1.10.10.60 1 50 5.2E-19 T 15-10-2018 C2I28_12025 39d412406e2bd3e0df675fa4ebeaa637 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.4E-5 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_12025 39d412406e2bd3e0df675fa4ebeaa637 192 Pfam PF13305 WHG domain 86 162 7.6E-11 T 15-10-2018 IPR025996 WHG domain C2I28_12025 39d412406e2bd3e0df675fa4ebeaa637 192 SUPERFAMILY SSF46689 8 73 7.7E-10 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_12025 39d412406e2bd3e0df675fa4ebeaa637 192 SUPERFAMILY SSF48498 78 185 1.63E-19 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_12025 39d412406e2bd3e0df675fa4ebeaa637 192 Gene3D G3DSA:1.10.357.10 51 186 9.9E-30 T 15-10-2018 C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 SUPERFAMILY SSF90123 10 325 1.44E-76 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 Gene3D G3DSA:1.20.1560.10 2 328 7.0E-83 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 Pfam PF00664 ABC transporter transmembrane region 24 296 6.3E-40 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 SMART SM00382 368 554 3.7E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 Gene3D G3DSA:3.40.50.300 334 594 3.7E-90 T 15-10-2018 C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 SUPERFAMILY SSF52540 338 578 2.45E-86 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_01975 9bc5f49c002e61bde50cca7cefa478a8 601 Pfam PF00005 ABC transporter 359 508 1.8E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12550 030f6794a4887eb5a73dcc1af82edc90 344 Pfam PF01032 FecCD transport family 27 337 3.2E-95 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_12550 030f6794a4887eb5a73dcc1af82edc90 344 SUPERFAMILY SSF81345 12 337 1.44E-83 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_12550 030f6794a4887eb5a73dcc1af82edc90 344 Gene3D G3DSA:1.10.3470.10 15 343 1.5E-96 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_22050 3539e2a4f807699f1ab2b8b7f31dd158 270 SUPERFAMILY SSF53850 37 266 9.78E-51 T 15-10-2018 C2I28_22050 3539e2a4f807699f1ab2b8b7f31dd158 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 264 1.8E-49 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_22050 3539e2a4f807699f1ab2b8b7f31dd158 270 Gene3D G3DSA:3.40.190.10 40 263 9.8E-77 T 15-10-2018 C2I28_22050 3539e2a4f807699f1ab2b8b7f31dd158 270 Gene3D G3DSA:3.40.190.10 107 227 9.8E-77 T 15-10-2018 C2I28_22050 3539e2a4f807699f1ab2b8b7f31dd158 270 SMART SM00062 38 265 2.9E-67 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_19995 ae99f48b3bff00579c84b25257ef96d1 312 SUPERFAMILY SSF103481 44 142 1.7E-9 T 15-10-2018 C2I28_19995 ae99f48b3bff00579c84b25257ef96d1 312 Pfam PF00892 EamA-like transporter family 156 289 2.0E-19 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_19995 ae99f48b3bff00579c84b25257ef96d1 312 Pfam PF00892 EamA-like transporter family 12 141 3.5E-15 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_19995 ae99f48b3bff00579c84b25257ef96d1 312 SUPERFAMILY SSF103481 192 293 1.7E-14 T 15-10-2018 C2I28_09565 8082d4d6339e5b564e7eb2f96b621edb 271 Gene3D G3DSA:3.30.70.120 183 257 3.7E-22 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_09565 8082d4d6339e5b564e7eb2f96b621edb 271 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 5 204 3.8E-63 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_09565 8082d4d6339e5b564e7eb2f96b621edb 271 PIRSF PIRSF006483 1 271 1.1E-93 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_09565 8082d4d6339e5b564e7eb2f96b621edb 271 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 210 264 3.1E-23 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_19545 eb4f5e901d7e4f1d4e72e67843415600 723 SUPERFAMILY SSF82866 146 326 4.19E-25 T 15-10-2018 C2I28_19545 eb4f5e901d7e4f1d4e72e67843415600 723 Pfam PF03176 MMPL family 385 711 1.4E-36 T 15-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I28_19545 eb4f5e901d7e4f1d4e72e67843415600 723 Pfam PF03176 MMPL family 59 356 6.2E-47 T 15-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I28_19545 eb4f5e901d7e4f1d4e72e67843415600 723 SUPERFAMILY SSF82866 501 706 6.41E-32 T 15-10-2018 C2I28_19545 eb4f5e901d7e4f1d4e72e67843415600 723 Gene3D G3DSA:1.20.1640.10 513 707 1.4E-5 T 15-10-2018 C2I28_13955 3fe56e1eb5516eeea4a79cfedc47cfb1 245 Gene3D G3DSA:3.40.50.1360 1 240 6.6E-101 T 15-10-2018 C2I28_13955 3fe56e1eb5516eeea4a79cfedc47cfb1 245 SUPERFAMILY SSF100950 1 242 6.28E-95 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_13955 3fe56e1eb5516eeea4a79cfedc47cfb1 245 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 226 5.5E-23 T 15-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 C2I28_13955 3fe56e1eb5516eeea4a79cfedc47cfb1 245 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 42.824 T 15-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 C2I28_13955 3fe56e1eb5516eeea4a79cfedc47cfb1 245 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 241 7.2E-93 T 15-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 C2I28_13955 3fe56e1eb5516eeea4a79cfedc47cfb1 245 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 15-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 C2I28_18815 209244402f9a0f35c6c1fec14ef540e1 517 SUPERFAMILY SSF46894 320 381 3.68E-8 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_18815 209244402f9a0f35c6c1fec14ef540e1 517 Gene3D G3DSA:1.10.10.10 291 386 2.4E-10 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18815 209244402f9a0f35c6c1fec14ef540e1 517 Pfam PF12146 Serine aminopeptidase, S33 24 215 4.8E-9 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_18815 209244402f9a0f35c6c1fec14ef540e1 517 SUPERFAMILY SSF53474 2 259 3.05E-35 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_18815 209244402f9a0f35c6c1fec14ef540e1 517 Gene3D G3DSA:3.40.50.1820 5 263 5.4E-34 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_18815 209244402f9a0f35c6c1fec14ef540e1 517 Pfam PF00486 Transcriptional regulatory protein, C terminal 329 380 8.5E-5 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_21365 118fe43ab0753c9cb47ce5a43c00aabd 190 Pfam PF01965 DJ-1/PfpI family 3 178 5.0E-40 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_21365 118fe43ab0753c9cb47ce5a43c00aabd 190 Gene3D G3DSA:3.40.50.880 1 187 3.0E-45 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_21365 118fe43ab0753c9cb47ce5a43c00aabd 190 SUPERFAMILY SSF52317 1 184 1.2E-44 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_07165 64ded0e93deeb4b999ee75e7148fb605 281 SUPERFAMILY SSF82549 1 281 1.18E-92 T 15-10-2018 C2I28_07165 64ded0e93deeb4b999ee75e7148fb605 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 280 2.6E-98 T 15-10-2018 IPR003797 DegV C2I28_07165 64ded0e93deeb4b999ee75e7148fb605 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 279 4.5E-104 T 15-10-2018 IPR003797 DegV C2I28_07165 64ded0e93deeb4b999ee75e7148fb605 281 Gene3D G3DSA:3.30.1180.10 154 281 3.6E-45 T 15-10-2018 C2I28_07165 64ded0e93deeb4b999ee75e7148fb605 281 Gene3D G3DSA:3.40.50.10170 1 152 4.8E-52 T 15-10-2018 C2I28_10850 0792a013a1468c50b69d5ec3b2e0b951 143 SUPERFAMILY SSF46785 2 136 1.25E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_10850 0792a013a1468c50b69d5ec3b2e0b951 143 Gene3D G3DSA:1.10.10.10 1 143 1.9E-56 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_10850 0792a013a1468c50b69d5ec3b2e0b951 143 Pfam PF02082 Transcriptional regulator 1 81 6.0E-23 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_11400 b1383324d87839d58f523c898b87d366 238 Pfam PF10737 Spore germination protein GerPC 128 228 4.6E-17 T 15-10-2018 IPR019673 Spore germination protein GerPC C2I28_11400 b1383324d87839d58f523c898b87d366 238 Pfam PF10737 Spore germination protein GerPC 25 92 1.2E-22 T 15-10-2018 IPR019673 Spore germination protein GerPC C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 Gene3D G3DSA:3.90.105.10 410 465 3.8E-19 T 15-10-2018 C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 407 461 8.3E-9 T 15-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 SUPERFAMILY SSF55904 334 469 1.44E-21 T 15-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 311 5.6E-76 T 15-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 Gene3D G3DSA:3.90.1150.150 278 363 1.8E-109 T 15-10-2018 C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 Gene3D G3DSA:3.40.640.10 47 277 1.8E-109 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_08250 99cf29f70fa29a0d80d58a148cef1740 474 SUPERFAMILY SSF53383 6 361 2.96E-77 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_04875 79d9d01cd1e98f0b0620350990ad689e 266 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 262 8.4E-128 T 15-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 C2I28_04875 79d9d01cd1e98f0b0620350990ad689e 266 SUPERFAMILY SSF52540 5 262 2.21E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04875 79d9d01cd1e98f0b0620350990ad689e 266 PIRSF PIRSF003092 1 266 8.3E-95 T 15-10-2018 IPR025501 ATP binding protein MinD C2I28_04875 79d9d01cd1e98f0b0620350990ad689e 266 Gene3D G3DSA:3.40.50.300 3 254 4.8E-72 T 15-10-2018 C2I28_04875 79d9d01cd1e98f0b0620350990ad689e 266 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 218 5.4E-25 T 15-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain C2I28_23950 09e682df23109dbd8c2c36741989ab94 191 Pfam PF05908 Poly-gamma-glutamate hydrolase 5 175 2.1E-48 T 15-10-2018 IPR008585 Poly-gamma-glutamate hydrolase C2I28_23950 09e682df23109dbd8c2c36741989ab94 191 Gene3D G3DSA:3.40.630.100 1 191 5.4E-54 T 15-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily C2I28_06185 3ecb5d5e09e9a5b1d90005aefd4c91f1 266 Pfam PF01903 CbiX 20 125 1.6E-29 T 15-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I28_06185 3ecb5d5e09e9a5b1d90005aefd4c91f1 266 Pfam PF01903 CbiX 145 245 4.5E-21 T 15-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I28_06185 3ecb5d5e09e9a5b1d90005aefd4c91f1 266 Gene3D G3DSA:3.40.50.1400 137 257 4.2E-21 T 15-10-2018 C2I28_06185 3ecb5d5e09e9a5b1d90005aefd4c91f1 266 Gene3D G3DSA:3.40.50.1400 12 135 2.1E-29 T 15-10-2018 C2I28_06185 3ecb5d5e09e9a5b1d90005aefd4c91f1 266 SUPERFAMILY SSF53800 12 252 1.96E-52 T 15-10-2018 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 Gene3D G3DSA:3.90.110.10 171 442 3.1E-102 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 Gene3D G3DSA:3.40.50.720 1 170 1.4E-73 T 15-10-2018 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 SUPERFAMILY SSF56327 173 439 1.75E-96 T 15-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 1.3E-75 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 6.7E-54 T 15-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 SUPERFAMILY SSF51735 4 168 6.72E-58 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 15-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 C2I28_12050 c30b6b3b2192c108d161fd695dbd4559 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 412 1.1E-46 T 15-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 C2I28_01315 b7f384b5c86b3a806f225357a0588699 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 340 5.3E-91 T 15-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 C2I28_01315 b7f384b5c86b3a806f225357a0588699 375 Gene3D G3DSA:3.20.20.70 4 370 1.7E-112 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_01315 b7f384b5c86b3a806f225357a0588699 375 SUPERFAMILY SSF51395 4 345 2.54E-95 T 15-10-2018 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 SUPERFAMILY SSF53328 105 300 1.83E-60 T 15-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 Gene3D G3DSA:3.30.70.260 16 102 1.6E-26 T 15-10-2018 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 Gene3D G3DSA:3.40.50.170 104 300 1.7E-71 T 15-10-2018 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 2.8E-61 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 2.8E-61 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 2.8E-61 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 2.8E-61 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 2.8E-61 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 2.8E-61 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 6.6E-127 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 Pfam PF01842 ACT domain 22 76 1.3E-10 T 15-10-2018 IPR002912 ACT domain C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 Pfam PF00551 Formyl transferase 104 281 2.9E-40 T 15-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 SUPERFAMILY SSF55021 21 100 1.35E-17 T 15-10-2018 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 46.748 T 15-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 C2I28_01865 877d733f8a37dd35c7761d10192903b0 300 PIRSF PIRSF036480 17 300 2.4E-113 T 15-10-2018 C2I28_05215 10ffe985a84065f547342983d5affcbc 257 Gene3D G3DSA:3.90.226.10 1 257 1.3E-90 T 15-10-2018 C2I28_05215 10ffe985a84065f547342983d5affcbc 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 255 7.5E-68 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_05215 10ffe985a84065f547342983d5affcbc 257 SUPERFAMILY SSF52096 1 256 6.26E-83 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_05215 10ffe985a84065f547342983d5affcbc 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 15-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 PIRSF PIRSF002888 2 333 9.6E-117 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 Gene3D G3DSA:3.40.1550.10 46 231 5.5E-61 T 15-10-2018 IPR028976 CheC-like superfamily C2I28_02475 64541d67dbcd446269469e2334b336f8 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 6.3E-30 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 6.3E-30 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 6.3E-30 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 6.3E-30 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 Pfam PF02154 Flagellar motor switch protein FliM 40 230 3.6E-72 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 323 1.0E-111 T 15-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 C2I28_02475 64541d67dbcd446269469e2334b336f8 333 SUPERFAMILY SSF103039 47 232 4.71E-30 T 15-10-2018 IPR028976 CheC-like superfamily C2I28_02475 64541d67dbcd446269469e2334b336f8 333 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 322 8.0E-21 T 15-10-2018 IPR001543 Surface presentation of antigen (SpoA) C2I28_02475 64541d67dbcd446269469e2334b336f8 333 SUPERFAMILY SSF101801 251 328 1.09E-17 T 15-10-2018 IPR036429 SpoA-like superfamily C2I28_02475 64541d67dbcd446269469e2334b336f8 333 Gene3D G3DSA:2.30.330.10 240 332 2.7E-9 T 15-10-2018 IPR036429 SpoA-like superfamily C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 PIRSF PIRSF002599 1 66 2.3E-24 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 PRINTS PR00050 Cold shock protein signature 4 19 4.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 PRINTS PR00050 Cold shock protein signature 24 33 4.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 PRINTS PR00050 Cold shock protein signature 39 57 4.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 SUPERFAMILY SSF50249 1 64 3.62E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 SMART SM00357 3 66 2.2E-31 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 Gene3D G3DSA:2.40.50.140 1 66 1.3E-31 T 15-10-2018 C2I28_16555 580eebdcfe4a8f675acbe9369c9e937c 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 6.6E-31 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_26540 dfa65757fbf2c29cfd210ce6ade5e0a1 279 Gene3D G3DSA:3.40.50.150 3 273 2.3E-25 T 15-10-2018 C2I28_26540 dfa65757fbf2c29cfd210ce6ade5e0a1 279 Pfam PF04072 Leucine carboxyl methyltransferase 45 178 6.2E-22 T 15-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 C2I28_26540 dfa65757fbf2c29cfd210ce6ade5e0a1 279 SUPERFAMILY SSF53335 8 261 2.33E-25 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 Gene3D G3DSA:3.40.190.10 49 261 3.4E-76 T 15-10-2018 C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 268 3.7E-68 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 Gene3D G3DSA:3.40.190.10 133 230 3.4E-76 T 15-10-2018 C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 SMART SM00062 50 269 5.9E-87 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 SMART SM00079 50 268 7.7E-4 T 15-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 73 86 - T 15-10-2018 IPR018313 Solute-binding protein family 3, conserved site C2I28_10875 b62a3d6e581535cd077ba0ccf0168536 273 SUPERFAMILY SSF53850 1 269 8.99E-74 T 15-10-2018 C2I28_07125 fed2242411875d92bffe661410b05665 140 SUPERFAMILY SSF141457 1 139 6.02E-45 T 15-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily C2I28_07125 fed2242411875d92bffe661410b05665 140 Pfam PF02623 FliW protein 19 138 4.9E-37 T 15-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 C2I28_07125 fed2242411875d92bffe661410b05665 140 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 140 24.206 T 15-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 C2I28_07125 fed2242411875d92bffe661410b05665 140 Gene3D G3DSA:2.30.290.10 1 140 2.5E-50 T 15-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 28.613 T 15-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Gene3D G3DSA:3.10.20.400 1 92 2.6E-38 T 15-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 51 100 3.0E-20 T 15-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Gene3D G3DSA:1.10.287.1080 115 206 6.9E-34 T 15-10-2018 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 101 4.2E-33 T 15-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 115 201 21.138 T 15-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 119 201 2.1E-32 T 15-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 SUPERFAMILY SSF101386 117 205 1.2E-27 T 15-10-2018 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 4 206 37.411 T 15-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 SUPERFAMILY SSF141734 3 107 4.45E-46 T 15-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 C2I28_06900 9fbabc153d8959d816ee805049df13c9 207 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 119 205 1.2E-17 T 15-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 C2I28_01775 02d137b80d5266c11c05f791cec18722 233 Gene3D G3DSA:3.40.1080.10 8 225 1.8E-69 T 15-10-2018 C2I28_01775 02d137b80d5266c11c05f791cec18722 233 Pfam PF01144 Coenzyme A transferase 12 221 4.8E-60 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_01775 02d137b80d5266c11c05f791cec18722 233 SMART SM00882 11 223 3.3E-66 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_01775 02d137b80d5266c11c05f791cec18722 233 SUPERFAMILY SSF100950 9 225 1.08E-68 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_01775 02d137b80d5266c11c05f791cec18722 233 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 11 223 1.2E-63 T 15-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 C2I28_14270 4840506896e1a02d93348f9269c75943 167 SUPERFAMILY SSF53155 13 80 1.73E-11 T 15-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I28_14270 4840506896e1a02d93348f9269c75943 167 SUPERFAMILY SSF46767 75 157 3.27E-28 T 15-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 C2I28_14270 4840506896e1a02d93348f9269c75943 167 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 15-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 C2I28_14270 4840506896e1a02d93348f9269c75943 167 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 157 36.696 T 15-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 C2I28_14270 4840506896e1a02d93348f9269c75943 167 Gene3D G3DSA:1.10.10.10 75 161 1.8E-32 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14270 4840506896e1a02d93348f9269c75943 167 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 76 156 5.9E-33 T 15-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I28_14270 4840506896e1a02d93348f9269c75943 167 Gene3D G3DSA:3.30.160.70 13 72 1.4E-9 T 15-10-2018 C2I28_14270 4840506896e1a02d93348f9269c75943 167 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 157 9.1E-29 T 15-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I28_06485 33530fb995f3cf042fe485540247c628 333 Gene3D G3DSA:2.70.70.10 119 330 8.9E-56 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_06485 33530fb995f3cf042fe485540247c628 333 Pfam PF01551 Peptidase family M23 208 309 2.3E-18 T 15-10-2018 IPR016047 Peptidase M23 C2I28_06485 33530fb995f3cf042fe485540247c628 333 SUPERFAMILY SSF51261 124 319 2.3E-32 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_13050 46cbaf02b9eede90daeb0c17847f3491 580 Pfam PF16949 Putative ATP-binding cassette 33 487 2.8E-18 T 15-10-2018 IPR031599 Putative ATP-binding cassette C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 Gene3D G3DSA:3.30.420.40 7 358 1.4E-157 T 15-10-2018 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 SUPERFAMILY SSF53067 120 350 2.15E-57 T 15-10-2018 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 182 199 - T 15-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 SUPERFAMILY SSF53067 6 174 6.72E-70 T 15-10-2018 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 8 356 9.9E-171 T 15-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 15-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 Pfam PF00871 Acetokinase family 8 355 1.4E-75 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 PIRSF PIRSF036458 4 359 3.9E-171 T 15-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 Hamap MF_00542 Probable butyrate kinase [buk]. 1 361 165.931 T 15-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 PRINTS PR00471 Acetate kinase family signature 277 290 5.6E-18 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 PRINTS PR00471 Acetate kinase family signature 300 316 5.6E-18 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 PRINTS PR00471 Acetate kinase family signature 182 203 5.6E-18 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 PRINTS PR00471 Acetate kinase family signature 345 357 5.6E-18 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 PRINTS PR00471 Acetate kinase family signature 8 19 5.6E-18 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_03770 bde50483290bd2caad9ffe72999b74ee 361 Gene3D G3DSA:3.30.420.40 140 335 1.4E-157 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 199 509 2.8E-158 T 15-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 SUPERFAMILY SSF52402 184 402 2.65E-61 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Gene3D G3DSA:3.30.300.10 390 509 4.0E-52 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 509 55.204 T 15-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 SUPERFAMILY SSF52317 4 224 1.87E-60 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 191 2.0E-84 T 15-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 SUPERFAMILY SSF54810 389 509 7.72E-51 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 76 92 7.7E-6 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 5 19 7.7E-6 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 7.7E-6 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 2.1E-7 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.1E-7 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 2.1E-7 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Gene3D G3DSA:3.40.50.620 197 389 2.4E-76 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Pfam PF00958 GMP synthase C terminal domain 417 508 1.1E-44 T 15-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Gene3D G3DSA:3.40.50.880 2 196 8.2E-57 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00097 Anthranilate synthase component II signature 49 58 2.3E-5 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00097 Anthranilate synthase component II signature 76 87 2.3E-5 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.3E-5 T 15-10-2018 C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Pfam PF02540 NAD synthase 210 279 9.2E-6 T 15-10-2018 IPR022310 NAD/GMP synthase C2I28_09365 a2840a0153779d78f8a2e107abc5e461 509 Pfam PF00117 Glutamine amidotransferase class-I 6 187 2.9E-45 T 15-10-2018 IPR017926 Glutamine amidotransferase C2I28_23050 3bcffb012bcfed94c10adffb4f114245 349 Pfam PF05425 Copper resistance protein D 166 262 1.6E-12 T 15-10-2018 IPR008457 Copper resistance protein D GO:0016021 C2I28_17910 da2ea2a70b20ba10120796134ae107a7 457 PIRSF PIRSF006603 1 455 2.7E-71 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_17910 da2ea2a70b20ba10120796134ae107a7 457 Pfam PF01554 MatE 20 180 5.2E-34 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_17910 da2ea2a70b20ba10120796134ae107a7 457 Pfam PF01554 MatE 247 407 2.9E-34 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_17910 da2ea2a70b20ba10120796134ae107a7 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 4.2E-104 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 Pfam PF00106 short chain dehydrogenase 8 198 9.8E-64 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 SUPERFAMILY SSF51735 2 221 1.28E-69 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.0E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.0E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.0E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.0E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.0E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PIRSF PIRSF000126 1 238 1.1E-64 T 15-10-2018 C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.0E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 5.0E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.0E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0067 T 15-10-2018 C2I28_14390 a07e7ffbd5dc0829594e2177aa2ce6d3 239 Gene3D G3DSA:3.40.50.720 1 237 1.6E-72 T 15-10-2018 C2I28_19910 90f9387d6d383111117185655380b68f 220 SMART SM00882 5 201 2.7E-56 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_19910 90f9387d6d383111117185655380b68f 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 4.3E-90 T 15-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 C2I28_19910 90f9387d6d383111117185655380b68f 220 Gene3D G3DSA:3.40.1080.10 1 212 1.5E-89 T 15-10-2018 C2I28_19910 90f9387d6d383111117185655380b68f 220 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 43 51 - T 15-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 C2I28_19910 90f9387d6d383111117185655380b68f 220 SUPERFAMILY SSF100950 2 213 1.59E-65 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_19910 90f9387d6d383111117185655380b68f 220 Pfam PF01144 Coenzyme A transferase 7 200 1.4E-30 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 Gene3D G3DSA:2.30.30.790 2 114 4.0E-16 T 15-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 113 6.5E-53 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 PIRSF PIRSF002191 1 114 1.3E-52 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 Pfam PF01245 Ribosomal protein L19 4 112 9.6E-55 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 SUPERFAMILY SSF50104 2 113 2.01E-49 T 15-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 33.473 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 15-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02610 66fe8c43cb50e60d665a75753b1c13d3 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 15-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_27050 5526981a0985cd5fdeb4c9a906e8bd6b 164 Gene3D G3DSA:3.40.1580.10 9 163 1.8E-24 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_27050 5526981a0985cd5fdeb4c9a906e8bd6b 164 SMART SM00860 11 157 1.5E-6 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_27050 5526981a0985cd5fdeb4c9a906e8bd6b 164 Pfam PF14568 SMI1-KNR4 cell-wall 15 155 8.4E-19 T 15-10-2018 C2I28_27050 5526981a0985cd5fdeb4c9a906e8bd6b 164 SUPERFAMILY SSF160631 6 159 1.96E-17 T 15-10-2018 C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 432 1.9E-205 T 15-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 10 433 1.9E-196 T 15-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 144 353 4.8E-77 T 15-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 Gene3D G3DSA:3.40.50.12240 12 435 7.4E-156 T 15-10-2018 C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 SUPERFAMILY SSF52540 91 359 1.49E-97 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 SMART SM00382 156 337 9.7E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 86 3.9E-6 T 15-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_02515 2c912091d1ca70b9c9abb62eb3e16387 437 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 15-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 SUPERFAMILY SSF88659 91 166 2.06E-15 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 164 1.0E-28 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 Pfam PF04542 Sigma-70 region 2 12 78 8.7E-14 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 Gene3D G3DSA:1.10.10.10 88 169 1.2E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 Gene3D G3DSA:1.10.1740.10 2 75 1.7E-22 T 15-10-2018 C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 SUPERFAMILY SSF88946 7 86 1.14E-19 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_26560 7ae7d0f9c7f9228e0a8e063ea5e4727c 175 Pfam PF08281 Sigma-70, region 4 108 156 1.9E-12 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_11830 4e71bae57409fd9048713a28b28b6b61 246 PRINTS PR00114 Serine/threonine phosphatase family signature 2 29 1.2E-8 T 15-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_11830 4e71bae57409fd9048713a28b28b6b61 246 PRINTS PR00114 Serine/threonine phosphatase family signature 227 243 1.2E-8 T 15-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_11830 4e71bae57409fd9048713a28b28b6b61 246 PRINTS PR00114 Serine/threonine phosphatase family signature 40 67 1.2E-8 T 15-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_11830 4e71bae57409fd9048713a28b28b6b61 246 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 1.6E-14 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_11830 4e71bae57409fd9048713a28b28b6b61 246 SUPERFAMILY SSF56300 1 240 4.46E-43 T 15-10-2018 C2I28_11830 4e71bae57409fd9048713a28b28b6b61 246 Gene3D G3DSA:3.60.21.10 1 246 3.4E-63 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_03050 0fc8b4fc44010256c9528dba7ef3abf7 399 SUPERFAMILY SSF52374 10 216 1.82E-19 T 15-10-2018 C2I28_03050 0fc8b4fc44010256c9528dba7ef3abf7 399 Gene3D G3DSA:3.40.50.620 1 240 9.8E-42 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_03050 0fc8b4fc44010256c9528dba7ef3abf7 399 Hamap MF_01539 UPF0348 protein . 2 397 41.071 T 15-10-2018 IPR008513 Uncharacterised protein family UPF0348 C2I28_03050 0fc8b4fc44010256c9528dba7ef3abf7 399 Pfam PF05636 HIGH Nucleotidyl Transferase 1 384 1.4E-141 T 15-10-2018 IPR008513 Uncharacterised protein family UPF0348 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 SUPERFAMILY SSF46894 7 72 2.21E-23 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 SMART SM00421 9 66 3.9E-25 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 3.4E-24 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.2E-12 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.2E-12 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.2E-12 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_05155 40a5c3077450c6971fabb99a139df31f 74 Gene3D G3DSA:1.10.10.10 1 74 1.6E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23315 e81b5eef77c5c28efcb3fbee4ad4e398 226 Pfam PF14344 Domain of unknown function (DUF4397) 160 226 1.9E-8 T 15-10-2018 IPR025510 Domain of unknown function DUF4397 C2I28_23315 e81b5eef77c5c28efcb3fbee4ad4e398 226 Pfam PF14344 Domain of unknown function (DUF4397) 38 153 9.9E-31 T 15-10-2018 IPR025510 Domain of unknown function DUF4397 C2I28_26015 4ac54573cc7477c256b08c4653405338 117 SUPERFAMILY SSF158560 1 106 3.14E-36 T 15-10-2018 C2I28_26015 4ac54573cc7477c256b08c4653405338 117 Pfam PF06304 Protein of unknown function (DUF1048) 7 107 7.0E-42 T 15-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 C2I28_26015 4ac54573cc7477c256b08c4653405338 117 Gene3D G3DSA:1.10.1900.10 1 109 1.4E-39 T 15-10-2018 C2I28_26015 4ac54573cc7477c256b08c4653405338 117 PIRSF PIRSF029876 3 111 3.9E-45 T 15-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 C2I28_17200 c9b9003f41b4126a03a5a2835b7bd422 113 Pfam PF12986 Domain of unknown function (DUF3870) 2 94 5.1E-29 T 15-10-2018 IPR024617 Domain of unknown function DUF3870 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 Gene3D G3DSA:1.20.1720.10 19 226 2.9E-37 T 15-10-2018 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 Pfam PF07690 Major Facilitator Superfamily 23 414 2.7E-44 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 442 4.1E-100 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 Gene3D G3DSA:1.20.1250.20 265 479 2.2E-20 T 15-10-2018 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 81 103 1.6E-7 T 15-10-2018 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 1.6E-7 T 15-10-2018 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 1.6E-7 T 15-10-2018 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 337 357 1.6E-7 T 15-10-2018 C2I28_00165 8e81b650c0977abf734b8de660dc1145 481 SUPERFAMILY SSF103473 12 475 2.49E-60 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_24060 dc33c13f00c67015691b753c110efd42 186 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 180 4.4E-51 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 SUPERFAMILY SSF51306 28 183 1.71E-51 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_24060 dc33c13f00c67015691b753c110efd42 186 ProSitePatterns PS00501 Signal peptidases I serine active site. 39 46 - T 15-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 Pfam PF00717 Peptidase S24-like 36 101 1.6E-20 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_24060 dc33c13f00c67015691b753c110efd42 186 ProSitePatterns PS00761 Signal peptidases I signature 3. 144 157 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 Gene3D G3DSA:2.10.109.10 56 185 8.4E-45 T 15-10-2018 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 ProSitePatterns PS00760 Signal peptidases I lysine active site. 79 91 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 30 46 2.8E-19 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 77 89 2.8E-19 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_24060 dc33c13f00c67015691b753c110efd42 186 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 158 2.8E-19 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_05580 20c70d6acc400ac1c3fe492a7a5ece80 563 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 562 21.495 T 15-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 C2I28_05580 20c70d6acc400ac1c3fe492a7a5ece80 563 Pfam PF06160 Septation ring formation regulator, EzrA 3 556 2.3E-166 T 15-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 SUPERFAMILY SSF102114 102 318 3.79E-15 T 15-10-2018 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 Gene3D G3DSA:1.10.150.530 1 77 2.7E-21 T 15-10-2018 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 Pfam PF13394 4Fe-4S single cluster domain 125 230 5.3E-6 T 15-10-2018 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 14 363 2.0E-162 T 15-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 Gene3D G3DSA:3.20.20.70 80 344 1.3E-99 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 359 74.164 T 15-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 Pfam PF04055 Radical SAM superfamily 120 293 3.0E-19 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_02755 6261f77d85a76291c18b55c153300ff9 363 PIRSF PIRSF006004 9 363 2.1E-139 T 15-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 SUPERFAMILY SSF50249 3 66 7.0E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 8.5E-31 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 Gene3D G3DSA:2.40.50.140 2 66 9.8E-30 T 15-10-2018 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 PRINTS PR00050 Cold shock protein signature 5 20 4.9E-20 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 PRINTS PR00050 Cold shock protein signature 40 58 4.9E-20 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 PRINTS PR00050 Cold shock protein signature 25 34 4.9E-20 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 SMART SM00357 4 67 2.8E-32 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_15140 8a8e3f32c970d68189371df07c156caf 67 PIRSF PIRSF002599 1 67 3.0E-25 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_08435 e12cb56610c32432ce0f6e47e3415df0 825 SMART SM00331 593 805 1.0E-58 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_08435 e12cb56610c32432ce0f6e47e3415df0 825 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 620 805 8.1E-35 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_08435 e12cb56610c32432ce0f6e47e3415df0 825 SMART SM00332 326 803 6.4E-6 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_08435 e12cb56610c32432ce0f6e47e3415df0 825 Gene3D G3DSA:3.60.40.10 587 825 6.6E-52 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_08435 e12cb56610c32432ce0f6e47e3415df0 825 SUPERFAMILY SSF81606 597 806 2.09E-20 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_08435 e12cb56610c32432ce0f6e47e3415df0 825 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 46 805 2.9E-269 T 15-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 Gene3D G3DSA:2.30.40.10 4 452 1.3E-188 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 455 5.1E-199 T 15-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 SUPERFAMILY SSF51556 53 383 9.9E-111 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 SUPERFAMILY SSF51338 342 459 4.8E-39 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 Gene3D G3DSA:3.20.20.140 53 381 1.3E-188 T 15-10-2018 C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 Pfam PF01979 Amidohydrolase family 49 437 1.2E-27 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_03675 4499281a3103cb7c598bed1b6167eb74 472 SUPERFAMILY SSF51338 2 64 8.64E-16 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 SUPERFAMILY SSF50249 2 136 7.43E-50 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PIRSF PIRSF002133 1 137 2.3E-50 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 1.2E-67 T 15-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 Gene3D G3DSA:2.40.50.140 1 140 2.0E-62 T 15-10-2018 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 7.2E-59 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 7.2E-59 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 7.2E-59 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 7.2E-59 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 7.2E-59 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 7.2E-59 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 Pfam PF00164 Ribosomal protein S12/S23 32 136 5.8E-39 T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.591 T 15-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08660 d05e6ed89b474d1cdd7054d2c73eaf65 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 15-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 Pfam PF13624 SurA N-terminal domain 3 127 2.0E-10 T 15-10-2018 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 Pfam PF13616 PPIC-type PPIASE domain 147 245 4.3E-29 T 15-10-2018 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 SUPERFAMILY SSF54534 130 242 8.5E-33 T 15-10-2018 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 182 203 - T 15-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 Hamap MF_01145 Foldase protein PrsA [prsA]. 3 290 16.179 T 15-10-2018 IPR023059 Foldase protein PrsA GO:0003755 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 Gene3D G3DSA:3.10.50.40 154 245 6.7E-57 T 15-10-2018 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 Gene3D G3DSA:1.10.4030.30 30 268 6.7E-57 T 15-10-2018 C2I28_18070 d5f7334e609cc2ce3aea68904ee0bace 291 SUPERFAMILY SSF109998 29 183 1.96E-32 T 15-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I28_05715 a16b40a49b9716212d16b79ec20665d6 285 SMART SM00849 50 257 2.7E-16 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_05715 a16b40a49b9716212d16b79ec20665d6 285 Pfam PF00753 Metallo-beta-lactamase superfamily 54 245 4.9E-15 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_05715 a16b40a49b9716212d16b79ec20665d6 285 SUPERFAMILY SSF56281 3 262 1.07E-45 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_05715 a16b40a49b9716212d16b79ec20665d6 285 Gene3D G3DSA:3.60.15.10 4 269 1.8E-85 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_11505 9b226542eeb7c3dd4a984cf2ca066623 287 Gene3D G3DSA:2.40.50.140 73 148 1.8E-24 T 15-10-2018 C2I28_11505 9b226542eeb7c3dd4a984cf2ca066623 287 PIRSF PIRSF012524 1 284 1.3E-104 T 15-10-2018 IPR014464 Conserved virulence factor B C2I28_11505 9b226542eeb7c3dd4a984cf2ca066623 287 Gene3D G3DSA:2.40.50.140 153 220 1.6E-19 T 15-10-2018 C2I28_11505 9b226542eeb7c3dd4a984cf2ca066623 287 Pfam PF13509 S1 domain 9 63 1.3E-19 T 15-10-2018 IPR039566 Conserved virulence factor B, S1 domain C2I28_11505 9b226542eeb7c3dd4a984cf2ca066623 287 Gene3D G3DSA:1.10.10.10 221 282 7.7E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26760 7d6792e11b35c8c0035912bdc7cc2094 367 Gene3D G3DSA:3.40.640.10 24 277 4.9E-50 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_26760 7d6792e11b35c8c0035912bdc7cc2094 367 Pfam PF03841 L-seryl-tRNA selenium transferase 56 279 6.9E-15 T 15-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 C2I28_26760 7d6792e11b35c8c0035912bdc7cc2094 367 SUPERFAMILY SSF53383 10 363 5.9E-38 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_26760 7d6792e11b35c8c0035912bdc7cc2094 367 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 6 364 9.0E-165 T 15-10-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.8E-19 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 SUPERFAMILY SSF47413 2 59 4.5E-19 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 15-10-2018 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 Gene3D G3DSA:3.40.50.2300 59 153 3.5E-19 T 15-10-2018 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 SMART SM00354 1 71 4.9E-30 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 Pfam PF13377 Periplasmic binding protein-like domain 173 333 2.4E-42 T 15-10-2018 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 Gene3D G3DSA:3.40.50.2300 158 336 6.4E-61 T 15-10-2018 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 Gene3D G3DSA:1.10.260.40 1 58 8.3E-23 T 15-10-2018 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.8E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.8E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_01245 6800878f514e2649baf70e37f32daca4 338 SUPERFAMILY SSF53822 60 335 1.67E-81 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_01655 82e78d08c2224d0316c5778840a50227 275 Gene3D G3DSA:1.10.1790.10 166 274 1.0E-31 T 15-10-2018 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 SMART SM01061 1 60 2.3E-17 T 15-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 SUPERFAMILY SSF50151 2 53 1.02E-14 T 15-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 Gene3D G3DSA:1.10.1790.10 61 164 4.4E-34 T 15-10-2018 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 Pfam PF00874 PRD domain 72 159 5.0E-25 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 Pfam PF00874 PRD domain 179 268 2.1E-24 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 SUPERFAMILY SSF63520 173 270 1.16E-29 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 Pfam PF03123 CAT RNA binding domain 2 55 6.5E-17 T 15-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 Gene3D G3DSA:2.30.24.10 1 55 7.7E-19 T 15-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 C2I28_01655 82e78d08c2224d0316c5778840a50227 275 SUPERFAMILY SSF63520 51 164 3.27E-31 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_03750 71ddabbfb22e348660012199def78f65 419 SUPERFAMILY SSF47005 105 150 3.14E-11 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_03750 71ddabbfb22e348660012199def78f65 419 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 189 411 8.1E-82 T 15-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I28_03750 71ddabbfb22e348660012199def78f65 419 SUPERFAMILY SSF52777 188 410 9.78E-84 T 15-10-2018 C2I28_03750 71ddabbfb22e348660012199def78f65 419 Gene3D G3DSA:2.40.50.100 2 104 8.1E-28 T 15-10-2018 C2I28_03750 71ddabbfb22e348660012199def78f65 419 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 15-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I28_03750 71ddabbfb22e348660012199def78f65 419 Gene3D G3DSA:3.30.559.10 171 419 9.6E-100 T 15-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I28_03750 71ddabbfb22e348660012199def78f65 419 Pfam PF00364 Biotin-requiring enzyme 5 77 1.3E-22 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_03750 71ddabbfb22e348660012199def78f65 419 Pfam PF02817 e3 binding domain 112 145 8.0E-12 T 15-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I28_03750 71ddabbfb22e348660012199def78f65 419 SUPERFAMILY SSF51230 3 92 1.15E-26 T 15-10-2018 IPR011053 Single hybrid motif C2I28_03750 71ddabbfb22e348660012199def78f65 419 Gene3D G3DSA:4.10.320.10 105 150 1.9E-15 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_12035 28be16213077d6d16a9606e686428539 101 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 94 1.4E-36 T 15-10-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 C2I28_12035 28be16213077d6d16a9606e686428539 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 2.1E-20 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_12035 28be16213077d6d16a9606e686428539 101 Gene3D G3DSA:3.40.50.2300 1 101 1.1E-37 T 15-10-2018 C2I28_12035 28be16213077d6d16a9606e686428539 101 SUPERFAMILY SSF52794 1 100 1.18E-35 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_06450 d740550013c98806ee2fbe1843a9b61f 166 PIRSF PIRSF019587 5 166 3.0E-78 T 15-10-2018 IPR026038 Putative phosphatidylglycerophosphatase C2I28_06450 d740550013c98806ee2fbe1843a9b61f 166 Gene3D G3DSA:1.10.3760.10 2 166 1.2E-73 T 15-10-2018 C2I28_06450 d740550013c98806ee2fbe1843a9b61f 166 SUPERFAMILY SSF101307 10 164 6.15E-54 T 15-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 C2I28_06450 d740550013c98806ee2fbe1843a9b61f 166 Pfam PF04608 Phosphatidylglycerophosphatase A 24 159 1.2E-19 T 15-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 SUPERFAMILY SSF52172 1 127 3.13E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 Gene3D G3DSA:1.10.10.10 132 227 1.5E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 Gene3D G3DSA:3.40.50.2300 1 131 4.4E-36 T 15-10-2018 C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 SMART SM00448 2 112 4.2E-40 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 Pfam PF00072 Response regulator receiver domain 4 113 2.4E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 SMART SM00862 149 225 2.1E-25 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 3.0E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_21120 203e94243384ce3b8f6080552fd1f78e 227 SUPERFAMILY SSF46894 125 226 3.12E-30 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_25020 e2e23ed736af25bdb3b3b3e678a89ac3 470 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 32 466 1.3E-145 T 15-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 C2I28_25020 e2e23ed736af25bdb3b3b3e678a89ac3 470 Gene3D G3DSA:1.20.1250.20 249 454 6.5E-12 T 15-10-2018 C2I28_25020 e2e23ed736af25bdb3b3b3e678a89ac3 470 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 83 110 - T 15-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 C2I28_25020 e2e23ed736af25bdb3b3b3e678a89ac3 470 Pfam PF13347 MFS/sugar transport protein 34 453 1.4E-103 T 15-10-2018 C2I28_25020 e2e23ed736af25bdb3b3b3e678a89ac3 470 Gene3D G3DSA:1.20.1250.20 35 229 8.0E-9 T 15-10-2018 C2I28_25020 e2e23ed736af25bdb3b3b3e678a89ac3 470 SUPERFAMILY SSF103473 35 453 1.15E-36 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_07270 d08a4f0225541c765a8f0db9897e2553 274 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 194 268 1.4E-18 T 15-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I28_07270 d08a4f0225541c765a8f0db9897e2553 274 Pfam PF00460 Flagella basal body rod protein 5 35 2.8E-9 T 15-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I28_07270 d08a4f0225541c765a8f0db9897e2553 274 SUPERFAMILY SSF117143 112 231 1.23E-16 T 15-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like C2I28_07270 d08a4f0225541c765a8f0db9897e2553 274 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 15-10-2018 IPR019776 Flagellar basal body rod protein, conserved site C2I28_07270 d08a4f0225541c765a8f0db9897e2553 274 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 159 2.6E-29 T 15-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 PRINTS PR01183 Ribonucleotide reductase large chain signature 638 665 2.8E-36 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 PRINTS PR01183 Ribonucleotide reductase large chain signature 573 596 2.8E-36 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 PRINTS PR01183 Ribonucleotide reductase large chain signature 507 530 2.8E-36 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 PRINTS PR01183 Ribonucleotide reductase large chain signature 262 281 2.8E-36 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 PRINTS PR01183 Ribonucleotide reductase large chain signature 545 567 2.8E-36 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 116 776 3.3E-180 T 15-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 130 180 2.4E-7 T 15-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 Pfam PF02867 Ribonucleotide reductase, barrel domain 187 766 5.6E-123 T 15-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 Gene3D G3DSA:3.20.70.20 345 781 2.5E-119 T 15-10-2018 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 Gene3D G3DSA:3.20.70.20 109 325 1.3E-42 T 15-10-2018 C2I28_03960 cf6cbdf80c47239cd41e6a4f213215cb 852 SUPERFAMILY SSF51998 129 833 4.58E-144 T 15-10-2018 C2I28_00500 f7780bd72125c0af8cd60be6c6808125 150 Pfam PF14119 Domain of unknown function (DUF4288) 13 108 5.3E-20 T 15-10-2018 IPR025630 Protein of unknown function DUF4288 C2I28_08695 bb5aee29d05a25130569266a6a4c89c0 95 Gene3D G3DSA:3.30.70.330 1 95 2.1E-32 T 15-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily C2I28_08695 bb5aee29d05a25130569266a6a4c89c0 95 SUPERFAMILY SSF54189 2 93 9.35E-32 T 15-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08695 bb5aee29d05a25130569266a6a4c89c0 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.986 T 15-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 C2I28_08695 bb5aee29d05a25130569266a6a4c89c0 95 Pfam PF00276 Ribosomal protein L23 6 90 1.0E-31 T 15-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 C2I28_08695 bb5aee29d05a25130569266a6a4c89c0 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 15-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 Pfam PF01368 DHH family 83 225 2.2E-10 T 15-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 562 3.1E-182 T 15-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 SUPERFAMILY SSF64182 57 452 3.66E-121 T 15-10-2018 IPR038763 DHH phosphoesterase superfamily C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 770 8.1E-62 T 15-10-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 Gene3D G3DSA:3.10.310.30 319 444 1.2E-34 T 15-10-2018 C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 Gene3D G3DSA:3.90.1640.30 57 318 6.5E-95 T 15-10-2018 C2I28_04715 3a29e5f38eff79e48e28a19f9cf32fa3 780 Pfam PF02272 DHHA1 domain 305 439 1.5E-21 T 15-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I28_05400 afc1f6ebe6dc587798cb3990cf8de2f7 428 SUPERFAMILY SSF53659 3 422 9.54E-142 T 15-10-2018 C2I28_05400 afc1f6ebe6dc587798cb3990cf8de2f7 428 SMART SM01329 21 418 1.2E-187 T 15-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I28_05400 afc1f6ebe6dc587798cb3990cf8de2f7 428 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 422 7.2E-223 T 15-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 C2I28_05400 afc1f6ebe6dc587798cb3990cf8de2f7 428 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 15-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 C2I28_05400 afc1f6ebe6dc587798cb3990cf8de2f7 428 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 1.6E-124 T 15-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 C2I28_05400 afc1f6ebe6dc587798cb3990cf8de2f7 428 Gene3D G3DSA:3.40.718.10 1 423 6.4E-183 T 15-10-2018 C2I28_08690 5ee515af0eff35dbe60256dc6457b8a9 207 SUPERFAMILY SSF52166 1 206 1.44E-86 T 15-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08690 5ee515af0eff35dbe60256dc6457b8a9 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.6E-85 T 15-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08690 5ee515af0eff35dbe60256dc6457b8a9 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.4E-74 T 15-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 C2I28_08690 5ee515af0eff35dbe60256dc6457b8a9 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 38.776 T 15-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08690 5ee515af0eff35dbe60256dc6457b8a9 207 Gene3D G3DSA:3.40.1370.10 3 207 2.2E-85 T 15-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_23920 d27b46b9c564138ff30fef1482f1151e 45 Pfam PF12841 YvrJ protein family 7 41 5.5E-16 T 15-10-2018 IPR024419 Protein of unknown function YvrJ C2I28_12875 c4f4c98915d90c05c159bb812b3ea82d 1082 Gene3D G3DSA:3.20.20.80 588 768 2.9E-5 T 15-10-2018 C2I28_12875 c4f4c98915d90c05c159bb812b3ea82d 1082 Gene3D G3DSA:3.20.20.80 388 516 2.7E-6 T 15-10-2018 C2I28_12875 c4f4c98915d90c05c159bb812b3ea82d 1082 SUPERFAMILY SSF51445 411 763 2.21E-14 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 2.6E-109 T 15-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 SUPERFAMILY SSF51735 3 257 2.45E-79 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.3E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 7.3E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 7.3E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.3E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.3E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 7.3E-38 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 Gene3D G3DSA:3.40.50.720 1 258 1.2E-77 T 15-10-2018 C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 5.1E-62 T 15-10-2018 C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.5E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.5E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19755 ed67318912ff9213542dbc4e3c05bb20 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.5E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 330 39.099 T 15-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 15-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 SUPERFAMILY SSF55307 204 319 1.6E-44 T 15-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 SMART SM00865 207 324 2.7E-56 T 15-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 12 326 3.1E-138 T 15-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 15-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 SMART SM00864 13 205 4.0E-117 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 PRINTS PR00423 Cell division protein FtsZ signature 212 233 4.1E-52 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 PRINTS PR00423 Cell division protein FtsZ signature 98 118 4.1E-52 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 PRINTS PR00423 Cell division protein FtsZ signature 189 211 4.1E-52 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 PRINTS PR00423 Cell division protein FtsZ signature 126 147 4.1E-52 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.9E-33 T 15-10-2018 IPR024757 Cell division protein FtsZ, C-terminal C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 SUPERFAMILY SSF52490 12 208 2.09E-72 T 15-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 1.3E-45 T 15-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 Gene3D G3DSA:3.30.1330.20 221 330 3.8E-40 T 15-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 C2I28_10690 27e5f4c30fe43442f03cb6e0d139c798 334 Gene3D G3DSA:3.40.50.1440 7 220 3.9E-84 T 15-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 C2I28_23360 f965c00e384b30c23abd93eeb41eba1f 288 PIRSF PIRSF006483 1 287 4.5E-94 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_23360 f965c00e384b30c23abd93eeb41eba1f 288 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 221 3.2E-65 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_23360 f965c00e384b30c23abd93eeb41eba1f 288 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 1.3E-22 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_23360 f965c00e384b30c23abd93eeb41eba1f 288 Gene3D G3DSA:3.30.70.120 198 273 2.2E-25 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_14195 4830ed63343f4af111bee61fda0c058d 65 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_14195 4830ed63343f4af111bee61fda0c058d 65 Gene3D G3DSA:1.10.8.910 5 65 8.2E-26 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_14195 4830ed63343f4af111bee61fda0c058d 65 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 6.0E-19 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_14195 4830ed63343f4af111bee61fda0c058d 65 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_12610 25441daf994b066afc68ca0d14a53756 254 SUPERFAMILY SSF52540 5 215 1.3E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12610 25441daf994b066afc68ca0d14a53756 254 SMART SM00382 32 212 3.5E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12610 25441daf994b066afc68ca0d14a53756 254 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_12610 25441daf994b066afc68ca0d14a53756 254 Pfam PF00005 ABC transporter 23 162 1.7E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12610 25441daf994b066afc68ca0d14a53756 254 Gene3D G3DSA:3.40.50.300 2 251 6.3E-63 T 15-10-2018 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00385 P450 superfamily signature 277 288 9.8E-7 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00385 P450 superfamily signature 242 259 9.8E-7 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00385 P450 superfamily signature 352 363 9.8E-7 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00385 P450 superfamily signature 343 352 9.8E-7 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 277 288 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 196 218 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 87 98 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 150 165 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 322 337 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 133 149 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 294 321 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 343 352 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 PRINTS PR00359 B-class P450 signature 352 363 3.0E-56 T 15-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 15-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 Gene3D G3DSA:1.10.630.10 2 404 9.1E-131 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 Pfam PF00067 Cytochrome P450 19 373 5.0E-47 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_00980 cb178e80609defcb66875a9592abdf55 404 SUPERFAMILY SSF48264 22 401 3.14E-101 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 292 1.1E-72 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 SUPERFAMILY SSF53686 3 306 1.17E-106 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 5.4E-147 T 15-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 Gene3D G3DSA:3.40.50.1100 7 300 3.8E-127 T 15-10-2018 C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 Gene3D G3DSA:3.40.50.1100 46 144 3.8E-127 T 15-10-2018 C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 3.7E-137 T 15-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I28_08475 4977a036b36bbebdbf8d5bea158bee5b 312 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 15-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 32 47 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 Pfam PF00375 Sodium:dicarboxylate symporter family 5 395 1.9E-118 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 290 313 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 Gene3D G3DSA:1.10.3860.10 1 409 1.2E-119 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 222 241 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 349 369 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 70 95 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 140 162 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 2.8E-36 T 15-10-2018 C2I28_24465 094f10a34add1ec12c1c1137f8040f89 414 SUPERFAMILY SSF118215 5 396 8.24E-113 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_18455 2a8900a077310368a4266c7c4b5e105f 311 SUPERFAMILY SSF52540 4 225 3.28E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18455 2a8900a077310368a4266c7c4b5e105f 311 Pfam PF00005 ABC transporter 20 161 2.5E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_18455 2a8900a077310368a4266c7c4b5e105f 311 SMART SM00382 28 212 3.5E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_18455 2a8900a077310368a4266c7c4b5e105f 311 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_18455 2a8900a077310368a4266c7c4b5e105f 311 Gene3D G3DSA:3.40.50.300 2 239 1.6E-59 T 15-10-2018 C2I28_26565 571ea05f789253b4c7728863fb7a9c98 184 Pfam PF01381 Helix-turn-helix 7 61 8.4E-17 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26565 571ea05f789253b4c7728863fb7a9c98 184 SUPERFAMILY SSF47413 1 66 3.75E-17 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_26565 571ea05f789253b4c7728863fb7a9c98 184 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 86 183 2.0E-9 T 15-10-2018 C2I28_26565 571ea05f789253b4c7728863fb7a9c98 184 SMART SM00530 6 61 1.4E-15 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26565 571ea05f789253b4c7728863fb7a9c98 184 Gene3D G3DSA:1.10.260.40 1 64 4.0E-22 T 15-10-2018 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 SUPERFAMILY SSF51569 30 350 1.1E-101 T 15-10-2018 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 94 350 7.7E-120 T 15-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 Pfam PF00793 DAHP synthetase I family 112 349 9.8E-80 T 15-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 SMART SM00830 9 88 4.3E-22 T 15-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 Pfam PF01817 Chorismate mutase type II 9 86 2.2E-19 T 15-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 Gene3D G3DSA:1.20.59.10 7 91 1.7E-28 T 15-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 Gene3D G3DSA:3.20.20.70 92 355 6.8E-102 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_23140 491bc4554cbbde9a806eb61a4c854374 357 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 100 8.8E-42 T 15-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 C2I28_00775 c529a3474fc63a999e173a86d83e1003 418 Pfam PF13641 Glycosyltransferase like family 2 56 277 2.6E-36 T 15-10-2018 C2I28_00775 c529a3474fc63a999e173a86d83e1003 418 SUPERFAMILY SSF53448 39 318 2.25E-60 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_00775 c529a3474fc63a999e173a86d83e1003 418 Gene3D G3DSA:3.90.550.10 38 271 4.9E-47 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_00775 c529a3474fc63a999e173a86d83e1003 418 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 15 412 4.1E-163 T 15-10-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0043708 C2I28_16450 fab89b7e06d2592edb0c4a2ddd18a666 108 Pfam PF11181 Heat induced stress protein YflT 4 102 1.4E-18 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 SUPERFAMILY SSF52540 47 278 8.45E-72 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 Pfam PF00005 ABC transporter 53 199 7.0E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 Gene3D G3DSA:3.40.50.300 23 276 3.2E-68 T 15-10-2018 C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 44 399 1.2E-105 T 15-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 Gene3D G3DSA:3.10.580.10 292 401 9.1E-13 T 15-10-2018 C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 Pfam PF00571 CBS domain 350 395 6.4E-5 T 15-10-2018 IPR000644 CBS domain C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 SUPERFAMILY SSF54631 291 400 6.12E-14 T 15-10-2018 C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15710 2a3d2aaa9b13e0a7ca8566752a53b51f 417 SMART SM00382 60 257 6.6E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 6.1E-8 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 SUPERFAMILY SSF51161 88 225 1.94E-48 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 1.1E-35 T 15-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 45.614 T 15-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 15-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 2.4E-10 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 118 2.7E-4 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Gene3D G3DSA:2.160.10.10 85 236 2.7E-50 T 15-10-2018 C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 2.4E-118 T 15-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 C2I28_14690 8f8697ef4d11f644956486518a0e3d2f 239 Gene3D G3DSA:3.30.70.250 1 84 8.1E-35 T 15-10-2018 C2I28_27440 742e066529a72575097ef7c702dcb7c9 414 Pfam PF13579 Glycosyl transferase 4-like domain 15 207 2.0E-12 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_27440 742e066529a72575097ef7c702dcb7c9 414 SUPERFAMILY SSF53756 2 404 7.85E-74 T 15-10-2018 C2I28_27440 742e066529a72575097ef7c702dcb7c9 414 Gene3D G3DSA:3.40.50.2000 220 388 1.1E-40 T 15-10-2018 C2I28_27440 742e066529a72575097ef7c702dcb7c9 414 Pfam PF00534 Glycosyl transferases group 1 226 381 2.8E-32 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_27440 742e066529a72575097ef7c702dcb7c9 414 Gene3D G3DSA:3.40.50.2000 1 219 1.3E-18 T 15-10-2018 C2I28_07440 415d97b4f17b02bf3d6ea4ed6c5e0853 428 Gene3D G3DSA:3.65.10.10 21 228 2.4E-155 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_07440 415d97b4f17b02bf3d6ea4ed6c5e0853 428 Gene3D G3DSA:3.65.10.10 6 412 2.4E-155 T 15-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 C2I28_07440 415d97b4f17b02bf3d6ea4ed6c5e0853 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 5.5E-167 T 15-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_07440 415d97b4f17b02bf3d6ea4ed6c5e0853 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 405 6.6E-89 T 15-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 C2I28_07440 415d97b4f17b02bf3d6ea4ed6c5e0853 428 SUPERFAMILY SSF55205 1 415 6.7E-131 T 15-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 C2I28_07440 415d97b4f17b02bf3d6ea4ed6c5e0853 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 41.235 T 15-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 C2I28_02270 2a400fceb386c58816e1fca2ae91d9ae 299 Gene3D G3DSA:3.40.50.720 7 288 2.6E-107 T 15-10-2018 C2I28_02270 2a400fceb386c58816e1fca2ae91d9ae 299 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 289 1.8E-138 T 15-10-2018 IPR014215 Dipicolinic acid synthetase subunit A C2I28_02270 2a400fceb386c58816e1fca2ae91d9ae 299 Gene3D G3DSA:3.40.50.720 126 272 2.6E-107 T 15-10-2018 C2I28_02270 2a400fceb386c58816e1fca2ae91d9ae 299 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 152 293 4.1E-8 T 15-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain C2I28_02270 2a400fceb386c58816e1fca2ae91d9ae 299 SUPERFAMILY SSF51735 131 269 2.2E-17 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_02270 2a400fceb386c58816e1fca2ae91d9ae 299 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 8.2E-34 T 15-10-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal C2I28_00720 9470c85a2ec10d8cb4806dd037647537 462 PIRSF PIRSF006060 1 461 2.1E-64 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_00720 9470c85a2ec10d8cb4806dd037647537 462 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_00720 9470c85a2ec10d8cb4806dd037647537 462 Pfam PF00324 Amino acid permease 14 438 2.3E-105 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_00720 9470c85a2ec10d8cb4806dd037647537 462 Gene3D G3DSA:1.20.1740.10 5 461 6.2E-58 T 15-10-2018 C2I28_04905 10eb594331a9d9d1f0267f1c614d5054 189 SUPERFAMILY SSF52972 2 184 9.81E-63 T 15-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I28_04905 10eb594331a9d9d1f0267f1c614d5054 189 PIRSF PIRSF006305 1 188 7.5E-61 T 15-10-2018 IPR003697 Maf-like protein GO:0047429 C2I28_04905 10eb594331a9d9d1f0267f1c614d5054 189 Pfam PF02545 Maf-like protein 5 184 2.6E-60 T 15-10-2018 IPR003697 Maf-like protein GO:0047429 C2I28_04905 10eb594331a9d9d1f0267f1c614d5054 189 Gene3D G3DSA:3.90.950.10 1 188 1.5E-72 T 15-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I28_04905 10eb594331a9d9d1f0267f1c614d5054 189 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 183 2.1E-66 T 15-10-2018 IPR003697 Maf-like protein GO:0047429 C2I28_04905 10eb594331a9d9d1f0267f1c614d5054 189 Hamap MF_00528 Septum formation protein Maf [maf]. 4 189 32.297 T 15-10-2018 IPR003697 Maf-like protein GO:0047429 C2I28_15795 5bcaf32e7cb25014c73a994614b42d93 319 SUPERFAMILY SSF51735 1 308 3.87E-54 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_15795 5bcaf32e7cb25014c73a994614b42d93 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 240 1.8E-24 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_15795 5bcaf32e7cb25014c73a994614b42d93 319 Gene3D G3DSA:3.40.50.720 1 311 3.5E-103 T 15-10-2018 C2I28_26855 a83e3e94d8115b24397b534907f83644 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 13 365 1.4E-56 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_26855 a83e3e94d8115b24397b534907f83644 368 Pfam PF03845 Spore germination protein 12 330 9.1E-44 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_12715 f74b750509ebd4d43a2d6a93688c909e 516 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 5.1E-94 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_12715 f74b750509ebd4d43a2d6a93688c909e 516 Gene3D G3DSA:1.20.1730.10 20 496 1.3E-73 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_12715 f74b750509ebd4d43a2d6a93688c909e 516 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 15-10-2018 IPR018212 Sodium/solute symporter, conserved site C2I28_12715 f74b750509ebd4d43a2d6a93688c909e 516 Pfam PF00474 Sodium:solute symporter family 33 434 6.1E-129 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_02815 d6e1bf1eed730a9e0005cbcd4bfb4235 212 Gene3D G3DSA:3.40.50.2020 1 212 1.7E-64 T 15-10-2018 C2I28_02815 d6e1bf1eed730a9e0005cbcd4bfb4235 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 30.16 T 15-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02815 d6e1bf1eed730a9e0005cbcd4bfb4235 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 179 1.4E-51 T 15-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02815 d6e1bf1eed730a9e0005cbcd4bfb4235 212 Pfam PF00156 Phosphoribosyl transferase domain 47 158 1.8E-21 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_02815 d6e1bf1eed730a9e0005cbcd4bfb4235 212 SUPERFAMILY SSF53271 11 208 2.1E-53 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_25720 adc740dc8028c7569083975b36e1dadd 484 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 445 7.2E-194 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_25720 adc740dc8028c7569083975b36e1dadd 484 Pfam PF02447 GntP family permease 1 444 2.7E-178 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_25720 adc740dc8028c7569083975b36e1dadd 484 PIRSF PIRSF002746 1 450 7.4E-176 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_15320 f2382dce9b22127d4780eb8ebef5280f 85 Pfam PF10752 Protein of unknown function (DUF2533) 1 84 2.0E-36 T 15-10-2018 IPR019688 Protein of unknown function DUF2533 C2I28_00770 45405a332e0601b02aacdb3edb98e76d 153 Pfam PF13994 PgaD-like protein 16 136 1.3E-7 T 15-10-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0043709 C2I28_00770 45405a332e0601b02aacdb3edb98e76d 153 TIGRFAM TIGR03940 PGA_PgaD: poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD 15 137 2.1E-10 T 15-10-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0043709 C2I28_09670 5f52e626eed3593a1d446049fd330752 230 SMART SM00448 4 115 2.8E-42 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09670 5f52e626eed3593a1d446049fd330752 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 4.8E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_09670 5f52e626eed3593a1d446049fd330752 230 SUPERFAMILY SSF52172 3 130 3.27E-41 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_09670 5f52e626eed3593a1d446049fd330752 230 Gene3D G3DSA:1.10.10.10 128 230 1.1E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09670 5f52e626eed3593a1d446049fd330752 230 SUPERFAMILY SSF46894 129 228 2.18E-31 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_09670 5f52e626eed3593a1d446049fd330752 230 SMART SM00862 153 228 1.6E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_09670 5f52e626eed3593a1d446049fd330752 230 Pfam PF00072 Response regulator receiver domain 6 116 4.3E-31 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09670 5f52e626eed3593a1d446049fd330752 230 Gene3D G3DSA:3.40.50.2300 1 124 6.5E-37 T 15-10-2018 C2I28_23055 131220840f6e6f93a73fd556ab571ff4 186 Gene3D G3DSA:2.60.40.1220 25 114 3.5E-27 T 15-10-2018 C2I28_23055 131220840f6e6f93a73fd556ab571ff4 186 Pfam PF04234 CopC domain 22 113 9.9E-21 T 15-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 C2I28_23055 131220840f6e6f93a73fd556ab571ff4 186 SUPERFAMILY SSF81296 21 113 1.26E-17 T 15-10-2018 IPR014756 Immunoglobulin E-set C2I28_22265 b1b0aa5bf0ae261b846e4ab3f6066765 223 Gene3D G3DSA:3.10.180.10 2 223 8.1E-64 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_22265 b1b0aa5bf0ae261b846e4ab3f6066765 223 SUPERFAMILY SSF54593 3 119 6.36E-12 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_07030 b4fea240d00cee0d8bc5eb2cd1a3555e 178 SUPERFAMILY SSF52218 3 175 4.49E-34 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_07030 b4fea240d00cee0d8bc5eb2cd1a3555e 178 Pfam PF03358 NADPH-dependent FMN reductase 3 122 7.7E-22 T 15-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I28_07030 b4fea240d00cee0d8bc5eb2cd1a3555e 178 Gene3D G3DSA:3.40.50.360 1 176 6.5E-45 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_01585 08dfe39dbabf34cbebd5b7c17f9f28a1 289 Gene3D G3DSA:3.40.50.300 1 240 8.8E-42 T 15-10-2018 C2I28_01585 08dfe39dbabf34cbebd5b7c17f9f28a1 289 SUPERFAMILY SSF52540 4 218 2.21E-41 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_01585 08dfe39dbabf34cbebd5b7c17f9f28a1 289 Pfam PF00005 ABC transporter 18 154 9.3E-20 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_01585 08dfe39dbabf34cbebd5b7c17f9f28a1 289 SMART SM00382 27 205 8.5E-4 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 15-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 Pfam PF05193 Peptidase M16 inactive domain 166 338 3.5E-41 T 15-10-2018 IPR007863 Peptidase M16, C-terminal C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 Gene3D G3DSA:3.30.830.10 1 215 3.1E-82 T 15-10-2018 C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 SUPERFAMILY SSF63411 221 399 2.23E-47 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 4.7E-49 T 15-10-2018 IPR011765 Peptidase M16, N-terminal C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 Gene3D G3DSA:3.30.830.10 218 411 2.5E-56 T 15-10-2018 C2I28_02280 a38009073bffabd1f6d2cf278ae1cfbb 414 SUPERFAMILY SSF63411 3 204 4.4E-65 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_02070 0fc31be023aedc5d309ebf5516b8cd26 420 Gene3D G3DSA:3.90.1150.60 17 411 5.3E-184 T 15-10-2018 C2I28_02070 0fc31be023aedc5d309ebf5516b8cd26 420 Pfam PF06838 Methionine gamma-lyase 13 414 3.3E-211 T 15-10-2018 IPR009651 Putative methionine gamma-lyase C2I28_02070 0fc31be023aedc5d309ebf5516b8cd26 420 SUPERFAMILY SSF53383 49 398 3.84E-45 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_02070 0fc31be023aedc5d309ebf5516b8cd26 420 Gene3D G3DSA:3.40.640.10 58 271 5.3E-184 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_21475 13fe6a971a24536a83963ac0f24610a9 176 Gene3D G3DSA:1.25.40.20 1 175 5.0E-31 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_21475 13fe6a971a24536a83963ac0f24610a9 176 SUPERFAMILY SSF48403 9 161 1.31E-28 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_21475 13fe6a971a24536a83963ac0f24610a9 176 Pfam PF12796 Ankyrin repeats (3 copies) 43 133 9.5E-17 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_21475 13fe6a971a24536a83963ac0f24610a9 176 SMART SM00248 72 101 0.02 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_21475 13fe6a971a24536a83963ac0f24610a9 176 SMART SM00248 34 67 1.0 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_21475 13fe6a971a24536a83963ac0f24610a9 176 SMART SM00248 104 133 0.006 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 6.6E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.6E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 6.6E-11 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.4E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.4E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.4E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.4E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.4E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.4E-41 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 SUPERFAMILY SSF51735 4 252 9.65E-85 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 250 4.0E-72 T 15-10-2018 C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 Gene3D G3DSA:3.40.50.720 1 252 9.8E-88 T 15-10-2018 C2I28_19875 a3cc2c01234f5345c35d785a76f377f5 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Gene3D G3DSA:1.10.10.1600 416 493 2.8E-22 T 15-10-2018 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Gene3D G3DSA:3.20.20.140 1 261 1.4E-78 T 15-10-2018 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Pfam PF14579 Helix-hairpin-helix motif 779 866 3.1E-26 T 15-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 SUPERFAMILY SSF160975 803 840 1.96E-6 T 15-10-2018 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 SMART SM00481 4 71 2.4E-23 T 15-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Pfam PF02811 PHP domain 5 166 4.5E-37 T 15-10-2018 IPR004013 PHP domain GO:0003824 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 SUPERFAMILY SSF89550 4 242 1.31E-11 T 15-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Pfam PF01336 OB-fold nucleic acid binding domain 964 1029 2.9E-6 T 15-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 284 705 4.8E-173 T 15-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 Gene3D G3DSA:1.10.150.870 758 854 6.1E-8 T 15-10-2018 C2I28_05450 6c5f65b8c3c7587d5ed4901b5781ae02 1116 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 991 0.0 T 15-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 C2I28_21795 412055e131db5f9b42af310dc9b71892 170 Gene3D G3DSA:1.20.120.450 1 157 3.3E-40 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_21795 412055e131db5f9b42af310dc9b71892 170 SUPERFAMILY SSF109854 3 135 3.51E-29 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_21795 412055e131db5f9b42af310dc9b71892 170 Pfam PF05163 DinB family 3 144 4.4E-27 T 15-10-2018 IPR007837 DNA damage-inducible protein DinB C2I28_05880 6211cd9b8fdba75630adee2582ff683e 256 Pfam PF00005 ABC transporter 23 162 2.2E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_05880 6211cd9b8fdba75630adee2582ff683e 256 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_05880 6211cd9b8fdba75630adee2582ff683e 256 Gene3D G3DSA:3.40.50.300 2 252 4.7E-61 T 15-10-2018 C2I28_05880 6211cd9b8fdba75630adee2582ff683e 256 SMART SM00382 32 212 7.8E-18 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_05880 6211cd9b8fdba75630adee2582ff683e 256 SUPERFAMILY SSF52540 22 214 6.19E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 284 9.7E-21 T 15-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 SUPERFAMILY SSF48179 169 286 2.83E-28 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 Gene3D G3DSA:1.10.1040.10 162 290 3.4E-36 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 SUPERFAMILY SSF51735 1 162 2.04E-40 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 Gene3D G3DSA:3.40.50.720 1 161 1.1E-45 T 15-10-2018 C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 15-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 PIRSF PIRSF000103 1 292 1.6E-79 T 15-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I28_21630 9d272e732c6f591ba45bf3c855636539 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 1.5E-37 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 SUPERFAMILY SSF55604 469 544 9.29E-18 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 438 529 9.3E-19 T 15-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 3 545 4.1E-288 T 15-10-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 Gene3D G3DSA:3.30.1360.60 465 544 9.0E-24 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 Pfam PF00367 phosphotransferase system, EIIB 473 503 5.7E-13 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 482 499 - T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_07665 f6a360ccfd1903308ab0ea17388c4a95 545 Pfam PF02378 Phosphotransferase system, EIIC 14 378 3.8E-57 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_18530 7580d3500e0548b96153900d999a0381 466 SUPERFAMILY SSF53720 14 451 5.5E-121 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_18530 7580d3500e0548b96153900d999a0381 466 Gene3D G3DSA:3.40.309.10 223 418 2.4E-174 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_18530 7580d3500e0548b96153900d999a0381 466 PIRSF PIRSF036492 2 466 1.6E-185 T 15-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 C2I28_18530 7580d3500e0548b96153900d999a0381 466 Gene3D G3DSA:3.40.605.10 23 438 2.4E-174 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_18530 7580d3500e0548b96153900d999a0381 466 Pfam PF00171 Aldehyde dehydrogenase family 10 437 1.1E-91 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_18530 7580d3500e0548b96153900d999a0381 466 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 219 226 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_03975 745d0a010016309af080724e320cbe0b 492 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.439 T 15-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 C2I28_03975 745d0a010016309af080724e320cbe0b 492 SUPERFAMILY SSF53383 9 483 6.77E-119 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_03975 745d0a010016309af080724e320cbe0b 492 Gene3D G3DSA:3.40.640.10 86 325 1.1E-59 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_03975 745d0a010016309af080724e320cbe0b 492 Gene3D G3DSA:3.90.1150.10 338 470 2.4E-50 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_03975 745d0a010016309af080724e320cbe0b 492 Pfam PF02347 Glycine cleavage system P-protein 45 300 2.5E-8 T 15-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 C2I28_13735 cb4f315e1db1bf1a03d676cc7b85337e 224 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 20 222 7.7E-76 T 15-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 C2I28_13735 cb4f315e1db1bf1a03d676cc7b85337e 224 Gene3D G3DSA:3.40.50.300 2 224 1.1E-74 T 15-10-2018 C2I28_13735 cb4f315e1db1bf1a03d676cc7b85337e 224 Pfam PF13614 AAA domain 51 178 1.1E-13 T 15-10-2018 IPR025669 AAA domain C2I28_13735 cb4f315e1db1bf1a03d676cc7b85337e 224 SUPERFAMILY SSF52540 41 216 8.61E-38 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_10350 c2c5b6ab8ebfcccda1f4f95adc7d92e7 631 PIRSF PIRSF000549 1 631 3.9E-262 T 15-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 C2I28_10350 c2c5b6ab8ebfcccda1f4f95adc7d92e7 631 SMART SM00763 21 371 1.9E-194 T 15-10-2018 IPR013153 PrkA AAA domain C2I28_10350 c2c5b6ab8ebfcccda1f4f95adc7d92e7 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 7.1E-93 T 15-10-2018 IPR010650 PrkA C-terminal domain C2I28_10350 c2c5b6ab8ebfcccda1f4f95adc7d92e7 631 Gene3D G3DSA:3.40.50.300 87 319 1.6E-7 T 15-10-2018 C2I28_10350 c2c5b6ab8ebfcccda1f4f95adc7d92e7 631 SUPERFAMILY SSF52540 68 444 1.9E-10 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_10350 c2c5b6ab8ebfcccda1f4f95adc7d92e7 631 Pfam PF08298 PrkA AAA domain 22 370 6.3E-150 T 15-10-2018 IPR013153 PrkA AAA domain C2I28_12895 c8579c846bcdb6277a1252882b1ac59a 268 Gene3D G3DSA:3.40.50.1820 31 268 4.4E-60 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_12895 c8579c846bcdb6277a1252882b1ac59a 268 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 29 266 3.5E-41 T 15-10-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like C2I28_12895 c8579c846bcdb6277a1252882b1ac59a 268 SUPERFAMILY SSF53474 32 254 4.75E-24 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 Gene3D G3DSA:3.30.930.10 1 324 1.1E-106 T 15-10-2018 C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 PIRSF PIRSF001549 3 380 5.9E-86 T 15-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 Pfam PF13393 Histidyl-tRNA synthetase 12 319 1.1E-77 T 15-10-2018 C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 Gene3D G3DSA:3.40.50.12590 326 393 9.7E-18 T 15-10-2018 C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 14 323 2.1E-98 T 15-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 SUPERFAMILY SSF55681 9 324 1.18E-64 T 15-10-2018 C2I28_06935 1241cf0ca4f0092e0b5e665580f556af 393 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 374 32.469 T 15-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 C2I28_08285 ebdc1a78cdfb39e9c4c17f699286ba34 95 Pfam PF01541 GIY-YIG catalytic domain 6 74 2.3E-16 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_08285 ebdc1a78cdfb39e9c4c17f699286ba34 95 SUPERFAMILY SSF82771 6 74 3.92E-14 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_08285 ebdc1a78cdfb39e9c4c17f699286ba34 95 Gene3D G3DSA:3.40.1440.10 1 95 1.2E-31 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_05280 3d8919350aeba6b89e9891ee5a6862c6 68 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 5.8E-32 T 15-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 C2I28_05280 3d8919350aeba6b89e9891ee5a6862c6 68 Pfam PF14098 Small, acid-soluble spore protein I 3 67 1.7E-29 T 15-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 C2I28_05280 3d8919350aeba6b89e9891ee5a6862c6 68 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 21.79 T 15-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 SUPERFAMILY SSF51735 1 154 7.45E-48 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 153 3.9E-46 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 296 1.3E-135 T 15-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 Gene3D G3DSA:3.40.50.720 1 166 1.7E-51 T 15-10-2018 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 SUPERFAMILY SSF48179 166 295 2.38E-40 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 SMART SM01350 168 299 2.1E-6 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 168 277 4.1E-24 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 60 89 1.4E-30 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 22 1.4E-30 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 157 185 1.4E-30 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 232 259 1.4E-30 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_11945 cef58998164a68d91e9c8b847a17d002 299 Gene3D G3DSA:1.10.1040.10 167 297 1.2E-50 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_08005 b3e2389012662859aa1441ba56951da1 117 SUPERFAMILY SSF54211 1 112 1.01E-34 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08005 b3e2389012662859aa1441ba56951da1 117 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 109 6.8E-31 T 15-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I28_08005 b3e2389012662859aa1441ba56951da1 117 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 110 5.0E-33 T 15-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I28_08005 b3e2389012662859aa1441ba56951da1 117 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 15-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 C2I28_08005 b3e2389012662859aa1441ba56951da1 117 Pfam PF00825 Ribonuclease P 1 107 7.0E-34 T 15-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I28_08005 b3e2389012662859aa1441ba56951da1 117 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 19.932 T 15-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 C2I28_08005 b3e2389012662859aa1441ba56951da1 117 Gene3D G3DSA:3.30.230.10 1 117 7.3E-38 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_16020 03c17be10e298b0da76b3295019261fa 312 Gene3D G3DSA:3.90.245.10 1 312 2.3E-114 T 15-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I28_16020 03c17be10e298b0da76b3295019261fa 312 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 300 4.2E-87 T 15-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I28_16020 03c17be10e298b0da76b3295019261fa 312 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 9 19 - T 15-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 C2I28_16020 03c17be10e298b0da76b3295019261fa 312 SUPERFAMILY SSF53590 3 307 3.01E-98 T 15-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I28_10470 922f277e2a0a67429693325cf0fb9135 446 Gene3D G3DSA:3.40.190.10 155 434 2.6E-127 T 15-10-2018 C2I28_10470 922f277e2a0a67429693325cf0fb9135 446 Pfam PF13416 Bacterial extracellular solute-binding protein 57 382 7.1E-56 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_10470 922f277e2a0a67429693325cf0fb9135 446 Gene3D G3DSA:3.40.190.10 43 395 2.6E-127 T 15-10-2018 C2I28_10470 922f277e2a0a67429693325cf0fb9135 446 SUPERFAMILY SSF53850 39 437 9.39E-86 T 15-10-2018 C2I28_10470 922f277e2a0a67429693325cf0fb9135 446 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 150 167 - T 15-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 C2I28_20270 fa31b211f531ce215bc5ca18733262b1 503 Gene3D G3DSA:3.40.50.12780 1 402 3.2E-104 T 15-10-2018 C2I28_20270 fa31b211f531ce215bc5ca18733262b1 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 489 4.5E-16 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_20270 fa31b211f531ce215bc5ca18733262b1 503 SUPERFAMILY SSF56801 2 500 1.7E-129 T 15-10-2018 C2I28_20270 fa31b211f531ce215bc5ca18733262b1 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_20270 fa31b211f531ce215bc5ca18733262b1 503 Pfam PF00501 AMP-binding enzyme 9 406 4.1E-97 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_20270 fa31b211f531ce215bc5ca18733262b1 503 Gene3D G3DSA:3.30.300.310 403 502 6.1E-28 T 15-10-2018 C2I28_26100 4101e93f151e92247067ea350d561e0f 250 Pfam PF00005 ABC transporter 25 171 3.1E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_26100 4101e93f151e92247067ea350d561e0f 250 SUPERFAMILY SSF52540 5 223 4.54E-72 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26100 4101e93f151e92247067ea350d561e0f 250 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_26100 4101e93f151e92247067ea350d561e0f 250 Gene3D G3DSA:3.40.50.300 2 247 7.7E-69 T 15-10-2018 C2I28_26100 4101e93f151e92247067ea350d561e0f 250 SMART SM00382 34 220 2.7E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14445 04976cf7c805d148f014bc278e0a1ac9 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 7.8E-29 T 15-10-2018 IPR018690 Protein of unknown function DUF2187 C2I28_19140 0a2cd18d13cc4be02cb42c6587ca0f04 80 Pfam PF11132 Transcriptional regulator protein (SplA) 3 75 2.1E-39 T 15-10-2018 IPR022608 Transcription regulator SplA C2I28_19140 0a2cd18d13cc4be02cb42c6587ca0f04 80 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 1 75 4.0E-22 T 15-10-2018 C2I28_00630 58b55cd455fb085bf27b569a699f261d 438 TIGRFAM TIGR00784 citMHS: citrate transporter 1 437 6.3E-203 T 15-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 C2I28_00630 58b55cd455fb085bf27b569a699f261d 438 Pfam PF03600 Citrate transporter 13 383 5.5E-53 T 15-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I28_10880 e0aa985ccf6f7d4c6be9ba37982101a4 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 119 16.614 T 15-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I28_10880 e0aa985ccf6f7d4c6be9ba37982101a4 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 114 1.8E-21 T 15-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 C2I28_09655 9990232902b2dd5abda28702a4d96fd8 179 Gene3D G3DSA:3.10.450.40 106 179 8.9E-18 T 15-10-2018 C2I28_09655 9990232902b2dd5abda28702a4d96fd8 179 Gene3D G3DSA:3.10.450.40 28 100 1.2E-14 T 15-10-2018 C2I28_09655 9990232902b2dd5abda28702a4d96fd8 179 Pfam PF03413 Peptidase propeptide and YPEB domain 39 95 3.0E-8 T 15-10-2018 IPR025711 PepSY domain C2I28_09655 9990232902b2dd5abda28702a4d96fd8 179 Pfam PF03413 Peptidase propeptide and YPEB domain 118 175 2.5E-14 T 15-10-2018 IPR025711 PepSY domain C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 PIRSF PIRSF000521 126 447 5.2E-36 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 PIRSF PIRSF000521 4 142 1.8E-4 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 14 447 2.4E-171 T 15-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 Gene3D G3DSA:3.90.1150.10 18 438 6.2E-131 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 Gene3D G3DSA:3.40.640.10 68 335 6.2E-131 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 SUPERFAMILY SSF53383 21 444 1.3E-111 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_01900 cd3eb8363bb69620b214076b6f91a9af 454 Pfam PF00202 Aminotransferase class-III 32 444 2.8E-91 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_21360 3f0027d11a06f098e2ae3a3542568437 370 Pfam PF13556 PucR C-terminal helix-turn-helix domain 310 367 2.5E-18 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_21360 3f0027d11a06f098e2ae3a3542568437 370 Pfam PF05651 Putative sugar diacid recognition 5 136 3.2E-44 T 15-10-2018 IPR008599 Putative sugar diacid recognition C2I28_21360 3f0027d11a06f098e2ae3a3542568437 370 Gene3D G3DSA:1.10.10.2840 251 370 1.2E-21 T 15-10-2018 C2I28_03180 d1177090574d49ddd8c03cb79cdb0c4d 255 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 249 32.968 T 15-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 C2I28_03180 d1177090574d49ddd8c03cb79cdb0c4d 255 SUPERFAMILY SSF51366 16 249 5.3E-78 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_03180 d1177090574d49ddd8c03cb79cdb0c4d 255 Gene3D G3DSA:3.20.20.70 1 253 6.5E-89 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03180 d1177090574d49ddd8c03cb79cdb0c4d 255 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 42 60 - T 15-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 C2I28_03180 d1177090574d49ddd8c03cb79cdb0c4d 255 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 247 5.9E-88 T 15-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-20 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.3E-9 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.3E-9 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.3E-9 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 SUPERFAMILY SSF53850 90 292 6.64E-41 T 15-10-2018 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 Pfam PF03466 LysR substrate binding domain 90 291 3.8E-45 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 Gene3D G3DSA:1.10.10.10 1 90 9.8E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 Gene3D G3DSA:3.40.190.290 91 295 8.3E-59 T 15-10-2018 C2I28_06675 5aca43cd75e5e921238360ba102950e7 297 SUPERFAMILY SSF46785 1 83 1.14E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04520 5dbd4813d9b53ee16a2e12c145c255ef 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 377 7.9E-155 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_04520 5dbd4813d9b53ee16a2e12c145c255ef 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_04520 5dbd4813d9b53ee16a2e12c145c255ef 377 PIRSF PIRSF001434 1 377 4.3E-145 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_04520 5dbd4813d9b53ee16a2e12c145c255ef 377 Gene3D G3DSA:3.40.640.10 2 245 1.3E-91 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_04520 5dbd4813d9b53ee16a2e12c145c255ef 377 SUPERFAMILY SSF53383 15 377 1.53E-118 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_04520 5dbd4813d9b53ee16a2e12c145c255ef 377 Gene3D G3DSA:3.90.1150.10 246 377 1.9E-53 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_19735 6ba741feb1b38cb0768bbf98c9e90db7 235 PIRSF PIRSF006171 4 234 7.9E-73 T 15-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I28_19735 6ba741feb1b38cb0768bbf98c9e90db7 235 Pfam PF12431 Transcriptional regulator 135 168 1.3E-4 T 15-10-2018 IPR028141 Transcriptional regulator C2I28_19735 6ba741feb1b38cb0768bbf98c9e90db7 235 SUPERFAMILY SSF52172 5 148 1.07E-32 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_19735 6ba741feb1b38cb0768bbf98c9e90db7 235 SMART SM00448 6 119 4.4E-28 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_19735 6ba741feb1b38cb0768bbf98c9e90db7 235 Pfam PF00072 Response regulator receiver domain 8 118 5.4E-24 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_19735 6ba741feb1b38cb0768bbf98c9e90db7 235 Gene3D G3DSA:3.40.50.2300 4 143 1.1E-29 T 15-10-2018 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 Gene3D G3DSA:2.60.40.420 116 274 5.1E-40 T 15-10-2018 IPR008972 Cupredoxin C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 19 240 5.6E-94 T 15-10-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 98 118 2.2E-6 T 15-10-2018 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 191 208 2.2E-6 T 15-10-2018 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 PRINTS PR01166 Cytochrome c oxidase subunit II signature 86 98 2.2E-6 T 15-10-2018 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 PIRSF PIRSF000292 2 314 5.2E-102 T 15-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 SUPERFAMILY SSF49503 125 274 1.33E-40 T 15-10-2018 IPR008972 Cupredoxin C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 36 110 4.3E-10 T 15-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 Gene3D G3DSA:1.10.287.90 28 115 8.8E-29 T 15-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23760 c4b0592027ac8bdd27d57b2e44d999cf 317 SUPERFAMILY SSF81464 19 119 2.45E-22 T 15-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_15530 2640401ca8bf6b49bf384682b6f5ae4d 284 Pfam PF06724 Domain of Unknown Function (DUF1206) 116 184 8.6E-9 T 15-10-2018 IPR009597 Domain of unknown function DUF1206 C2I28_15530 2640401ca8bf6b49bf384682b6f5ae4d 284 Pfam PF06724 Domain of Unknown Function (DUF1206) 211 279 1.6E-19 T 15-10-2018 IPR009597 Domain of unknown function DUF1206 C2I28_15530 2640401ca8bf6b49bf384682b6f5ae4d 284 Pfam PF06724 Domain of Unknown Function (DUF1206) 33 100 1.5E-17 T 15-10-2018 IPR009597 Domain of unknown function DUF1206 C2I28_03970 abf008e70a5012f6e0ec42c89d7bc018 127 SMART SM00450 30 125 1.4E-25 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_03970 abf008e70a5012f6e0ec42c89d7bc018 127 SUPERFAMILY SSF52821 10 121 2.75E-32 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_03970 abf008e70a5012f6e0ec42c89d7bc018 127 Pfam PF00581 Rhodanese-like domain 43 120 1.7E-18 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_03970 abf008e70a5012f6e0ec42c89d7bc018 127 Gene3D G3DSA:3.40.250.10 31 127 8.6E-29 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_05710 69348d5d4e19a66fdfb37f917dd573fd 103 Pfam PF03413 Peptidase propeptide and YPEB domain 27 96 4.4E-5 T 15-10-2018 IPR025711 PepSY domain C2I28_23320 45960d78a0b3c38ce8eea5d3db0ae643 177 Gene3D G3DSA:3.30.460.10 2 177 5.8E-37 T 15-10-2018 C2I28_23320 45960d78a0b3c38ce8eea5d3db0ae643 177 SUPERFAMILY SSF81301 4 175 2.19E-33 T 15-10-2018 C2I28_23320 45960d78a0b3c38ce8eea5d3db0ae643 177 Pfam PF04229 GrpB protein 3 175 2.4E-33 T 15-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 PRINTS PR00050 Cold shock protein signature 4 19 2.3E-18 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 PRINTS PR00050 Cold shock protein signature 39 57 2.3E-18 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 PRINTS PR00050 Cold shock protein signature 24 33 2.3E-18 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 Pfam PF00313 'Cold-shock' DNA-binding domain 2 65 5.0E-30 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 SMART SM00357 3 65 3.5E-27 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 PIRSF PIRSF002599 1 65 2.1E-24 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 SUPERFAMILY SSF50249 1 64 1.63E-24 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_13060 7fb084c2ca7f912847ec0dc0130a0f02 65 Gene3D G3DSA:2.40.50.140 1 65 3.7E-30 T 15-10-2018 C2I28_20950 c79e669a5a1fa2dede68e879c878f175 277 SUPERFAMILY SSF55447 179 276 6.93E-14 T 15-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily C2I28_20950 c79e669a5a1fa2dede68e879c878f175 277 SMART SM01092 179 274 6.9E-10 T 15-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal C2I28_20950 c79e669a5a1fa2dede68e879c878f175 277 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 169 2.7E-30 T 15-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 C2I28_20950 c79e669a5a1fa2dede68e879c878f175 277 Gene3D G3DSA:3.30.390.50 176 274 2.9E-6 T 15-10-2018 C2I28_20950 c79e669a5a1fa2dede68e879c878f175 277 SUPERFAMILY SSF56176 1 169 3.56E-36 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_20950 c79e669a5a1fa2dede68e879c878f175 277 Gene3D G3DSA:3.30.465.10 4 172 4.8E-35 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_24985 63aabdaaa98e811214435ae03efe07bc 246 Pfam PF02517 CAAX protease self-immunity 104 201 1.2E-15 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 Gene3D G3DSA:2.40.110.10 134 223 4.0E-21 T 15-10-2018 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 244 360 3.1E-15 T 15-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 Gene3D G3DSA:1.20.140.10 239 378 2.7E-31 T 15-10-2018 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 SUPERFAMILY SSF47203 239 379 8.54E-26 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 216 4.7E-15 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 Gene3D G3DSA:1.10.540.10 4 119 2.1E-19 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 SUPERFAMILY SSF56645 22 227 2.49E-41 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 24 95 1.3E-7 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 PIRSF PIRSF016578 1 97 9.8E-10 T 15-10-2018 C2I28_22780 1dcaf75bfa50d0e54cb89cc3001ce082 381 PIRSF PIRSF016578 137 381 1.1E-23 T 15-10-2018 C2I28_27380 d061c281672451fd452a6d4ed767abe1 218 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 121 1.5E-15 T 15-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 C2I28_27380 d061c281672451fd452a6d4ed767abe1 218 SUPERFAMILY SSF102588 5 214 2.49E-34 T 15-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I28_27380 d061c281672451fd452a6d4ed767abe1 218 Gene3D G3DSA:3.40.50.10320 2 217 1.2E-47 T 15-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I28_04880 8471bf37907e53dcd163b208b390d3ff 227 SUPERFAMILY SSF63848 106 206 1.26E-29 T 15-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 C2I28_04880 8471bf37907e53dcd163b208b390d3ff 227 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 107 207 2.9E-31 T 15-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 C2I28_04880 8471bf37907e53dcd163b208b390d3ff 227 Gene3D G3DSA:2.160.20.70 100 227 2.4E-36 T 15-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 C2I28_04880 8471bf37907e53dcd163b208b390d3ff 227 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 209 6.9E-38 T 15-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 C2I28_04880 8471bf37907e53dcd163b208b390d3ff 227 Gene3D G3DSA:3.30.160.540 7 86 3.5E-27 T 15-10-2018 C2I28_04880 8471bf37907e53dcd163b208b390d3ff 227 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 211 21.847 T 15-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 C2I28_14135 9e5eadf7ded5810ff14c550df7e40aa5 260 Gene3D G3DSA:3.90.1200.10 96 260 1.1E-18 T 15-10-2018 C2I28_14135 9e5eadf7ded5810ff14c550df7e40aa5 260 Pfam PF01636 Phosphotransferase enzyme family 23 241 7.0E-26 T 15-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I28_14135 9e5eadf7ded5810ff14c550df7e40aa5 260 SUPERFAMILY SSF56112 9 243 3.23E-32 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_01410 b19e16025ce1f92155f2d2cd3f8bc41c 467 Pfam PF00324 Amino acid permease 18 449 1.4E-120 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_01410 b19e16025ce1f92155f2d2cd3f8bc41c 467 Gene3D G3DSA:1.20.1740.10 10 463 5.9E-64 T 15-10-2018 C2I28_01410 b19e16025ce1f92155f2d2cd3f8bc41c 467 PIRSF PIRSF006060 1 464 2.2E-75 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_01410 b19e16025ce1f92155f2d2cd3f8bc41c 467 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_13230 58ebce5b9a14d229b01d8c5c87c1a698 297 Gene3D G3DSA:3.30.420.40 109 280 4.1E-58 T 15-10-2018 C2I28_13230 58ebce5b9a14d229b01d8c5c87c1a698 297 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 256 4.1E-19 T 15-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 C2I28_13230 58ebce5b9a14d229b01d8c5c87c1a698 297 SUPERFAMILY SSF53067 1 103 3.13E-14 T 15-10-2018 C2I28_13230 58ebce5b9a14d229b01d8c5c87c1a698 297 Gene3D G3DSA:3.30.420.40 4 288 4.1E-58 T 15-10-2018 C2I28_13230 58ebce5b9a14d229b01d8c5c87c1a698 297 SUPERFAMILY SSF53067 110 296 9.81E-39 T 15-10-2018 C2I28_07670 ba86ecd9f2c5ab2d60ad8d5904b3b173 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 20 253 3.7E-9 T 15-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I28_07670 ba86ecd9f2c5ab2d60ad8d5904b3b173 261 SUPERFAMILY SSF56219 1 260 4.58E-37 T 15-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I28_07670 ba86ecd9f2c5ab2d60ad8d5904b3b173 261 Gene3D G3DSA:3.60.10.10 1 261 8.8E-79 T 15-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I28_14835 aeaa03c6ff2547e34d03f8f7d907e304 61 Pfam PF17259 Family of unknown function (DUF5325) 1 61 5.4E-30 T 15-10-2018 IPR035211 Protein of unknown function DUF5325 C2I28_14835 aeaa03c6ff2547e34d03f8f7d907e304 61 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 1 56 3.0E-5 T 15-10-2018 IPR035211 Protein of unknown function DUF5325 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Pfam PF00676 Dehydrogenase E1 component 222 531 6.6E-73 T 15-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Gene3D G3DSA:3.40.50.11610 732 939 1.1E-152 T 15-10-2018 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 941 0.0 T 15-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 SMART SM00861 596 792 3.0E-42 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Pfam PF02779 Transketolase, pyrimidine binding domain 595 792 5.6E-53 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 PIRSF PIRSF000157 2 943 0.0 T 15-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Gene3D G3DSA:3.40.50.12470 554 814 1.1E-152 T 15-10-2018 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Gene3D G3DSA:3.40.50.970 154 536 5.1E-134 T 15-10-2018 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 2 943 22.959 T 15-10-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 SUPERFAMILY SSF52518 151 531 2.52E-73 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 SUPERFAMILY SSF52518 578 799 5.69E-41 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_22655 cc5feb6824ac6631962bfb3612ca1a5d 953 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 796 941 1.0E-41 T 15-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 36.579 T 15-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 SMART SM00363 92 156 7.8E-22 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 SMART SM01390 3 91 3.0E-45 T 15-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 SUPERFAMILY SSF55174 2 200 4.19E-71 T 15-10-2018 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 2.5E-86 T 15-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 Gene3D G3DSA:1.10.1050.10 6 200 4.0E-76 T 15-10-2018 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 Gene3D G3DSA:3.10.290.10 91 185 4.0E-76 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 15-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 Pfam PF01479 S4 domain 93 139 1.0E-22 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_05600 b23e0a8231ea408b2372f718d928f2a9 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 5.0E-28 T 15-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 C2I28_05825 938f604f703ceddf5f4aa38aaf83b432 189 SUPERFAMILY SSF53335 17 146 1.33E-23 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_05825 938f604f703ceddf5f4aa38aaf83b432 189 Pfam PF06962 Putative rRNA methylase 48 187 3.9E-53 T 15-10-2018 IPR010719 Putative rRNA methylase C2I28_05825 938f604f703ceddf5f4aa38aaf83b432 189 Gene3D G3DSA:3.40.50.150 1 189 3.0E-72 T 15-10-2018 C2I28_01525 0d04d685c4f86e591b6d4b6d51f6c2ef 239 Gene3D G3DSA:3.40.50.1220 14 238 5.2E-70 T 15-10-2018 C2I28_01525 0d04d685c4f86e591b6d4b6d51f6c2ef 239 Pfam PF02146 Sir2 family 23 194 2.5E-50 T 15-10-2018 IPR003000 Sirtuin family GO:0070403 C2I28_01525 0d04d685c4f86e591b6d4b6d51f6c2ef 239 Gene3D G3DSA:3.30.1600.10 32 166 5.2E-70 T 15-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily C2I28_01525 0d04d685c4f86e591b6d4b6d51f6c2ef 239 SUPERFAMILY SSF52467 2 238 4.09E-72 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 Gene3D G3DSA:3.40.605.10 24 462 1.5E-161 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 9 485 2.4E-187 T 15-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 3 485 74.542 T 15-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 SUPERFAMILY SSF53720 4 485 3.53E-157 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 Gene3D G3DSA:3.40.309.10 254 454 1.5E-161 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 Pfam PF00171 Aldehyde dehydrogenase family 17 481 8.8E-157 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_10605 c4ba277a36a724849f00f44dc5ebfc8f 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_01120 f781e29511521c61feb8f1bd7990809b 300 SUPERFAMILY SSF109998 45 198 5.1E-8 T 15-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I28_01120 f781e29511521c61feb8f1bd7990809b 300 Pfam PF13145 PPIC-type PPIASE domain 155 265 2.0E-7 T 15-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 C2I28_01120 f781e29511521c61feb8f1bd7990809b 300 SUPERFAMILY SSF54534 174 260 7.06E-5 T 15-10-2018 C2I28_01120 f781e29511521c61feb8f1bd7990809b 300 Gene3D G3DSA:1.10.4030.30 75 276 3.6E-10 T 15-10-2018 C2I28_01120 f781e29511521c61feb8f1bd7990809b 300 Gene3D G3DSA:3.10.50.40 172 262 3.6E-10 T 15-10-2018 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Gene3D G3DSA:3.30.930.10 3 242 2.2E-95 T 15-10-2018 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 SUPERFAMILY SSF101353 246 443 1.31E-69 T 15-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Pfam PF01411 tRNA synthetases class II (A) 8 557 1.5E-215 T 15-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 184.293 T 15-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 SMART SM00863 655 698 3.0E-21 T 15-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Gene3D G3DSA:2.40.30.130 457 550 1.9E-10 T 15-10-2018 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 9.6E-19 T 15-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Gene3D G3DSA:3.30.980.10 564 699 2.9E-51 T 15-10-2018 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 SUPERFAMILY SSF55186 555 719 3.01E-53 T 15-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 SUPERFAMILY SSF50447 455 552 2.71E-16 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 1.6E-32 T 15-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 1.6E-32 T 15-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.6E-32 T 15-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 1.6E-32 T 15-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.6E-32 T 15-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Gene3D G3DSA:3.10.310.40 766 876 1.7E-36 T 15-10-2018 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Gene3D G3DSA:3.30.54.20 626 679 2.9E-51 T 15-10-2018 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 Pfam PF02272 DHHA1 domain 735 874 3.9E-31 T 15-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 15-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 C2I28_04605 76d912fa0e9e259b365a2303d79a9bb8 877 SUPERFAMILY SSF55681 5 245 5.47E-89 T 15-10-2018 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 3.6E-34 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 3.6E-34 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 3.6E-34 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 3.6E-34 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 PIRSF PIRSF001365 1 290 2.4E-100 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 Gene3D G3DSA:3.20.20.70 1 290 5.0E-118 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 9.1E-114 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 64.515 T 15-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 15-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 SUPERFAMILY SSF51569 2 288 7.54E-105 T 15-10-2018 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 15-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 289 1.7E-113 T 15-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 C2I28_02250 b44c97c045e1d1571f8a423c242e7ed5 290 SMART SM01130 3 290 9.3E-139 T 15-10-2018 IPR002220 DapA-like GO:0016829 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Pfam PF01642 Methylmalonyl-CoA mutase 555 1072 5.4E-139 T 15-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Gene3D G3DSA:3.40.50.300 197 406 7.4E-58 T 15-10-2018 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 7 1080 16.705 T 15-10-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Pfam PF02310 B12 binding domain 10 111 1.3E-11 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Pfam PF03308 ArgK protein 161 432 8.7E-41 T 15-10-2018 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 SUPERFAMILY SSF51703 498 1076 3.92E-149 T 15-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 709 1079 8.0E-92 T 15-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Gene3D G3DSA:3.40.50.280 3 143 1.2E-56 T 15-10-2018 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 Gene3D G3DSA:3.20.20.240 480 1080 8.8E-187 T 15-10-2018 C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 SUPERFAMILY SSF52540 123 461 2.99E-57 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07475 8dbaf2f6ce8717fffe254f6b469a498e 1080 SUPERFAMILY SSF52242 3 138 1.31E-38 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Gene3D G3DSA:3.30.420.40 5 347 7.3E-152 T 15-10-2018 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 358 377 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 172 182 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 335 355 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 439 455 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 3 16 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 53 61 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 112 132 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 31 43 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 PRINTS PR00301 70kDa heat shock protein signature 304 320 7.9E-80 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 SUPERFAMILY SSF53067 1 157 3.89E-58 T 15-10-2018 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Gene3D G3DSA:3.90.640.10 198 279 7.3E-152 T 15-10-2018 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 SUPERFAMILY SSF100920 354 510 2.49E-61 T 15-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 15-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 SUPERFAMILY SSF100934 477 576 3.79E-14 T 15-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Gene3D G3DSA:2.60.34.10 348 476 3.1E-57 T 15-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Gene3D G3DSA:1.20.1270.10 477 579 4.9E-26 T 15-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 SUPERFAMILY SSF53067 160 352 1.98E-66 T 15-10-2018 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 15-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Pfam PF00012 Hsp70 protein 76 573 1.1E-220 T 15-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Gene3D G3DSA:3.30.420.40 159 337 7.3E-152 T 15-10-2018 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 1.1E-283 T 15-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 600 37.055 T 15-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 C2I28_04380 e6084f95b24742e7072bc9196e2f7a0e 605 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 15-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 Gene3D G3DSA:1.20.1720.10 36 267 3.8E-40 T 15-10-2018 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 322 346 1.4E-8 T 15-10-2018 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 37 61 1.4E-8 T 15-10-2018 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 128 148 1.4E-8 T 15-10-2018 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 1.4E-8 T 15-10-2018 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 Gene3D G3DSA:1.20.1250.20 280 512 3.1E-25 T 15-10-2018 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 Pfam PF07690 Major Facilitator Superfamily 39 430 2.4E-49 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 34 493 7.5E-122 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_21705 b9cf186b25846dbb57129bcb565af89e 513 SUPERFAMILY SSF103473 26 499 6.93E-68 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 Gene3D G3DSA:3.40.190.10 247 505 4.5E-100 T 15-10-2018 C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 SUPERFAMILY SSF161098 14 198 9.03E-43 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 196 8.5E-25 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 Gene3D G3DSA:3.40.190.120 340 443 4.5E-100 T 15-10-2018 C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 237 499 1.7E-64 T 15-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 SUPERFAMILY SSF53850 237 505 3.62E-72 T 15-10-2018 C2I28_01195 05a3c9cfd359d50287c4ce45b4268896 507 Gene3D G3DSA:1.10.3720.10 10 207 2.9E-37 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_06665 be7d0c1f45ff3dcb4e4af4c68bb3a625 400 SUPERFAMILY SSF103473 9 398 1.7E-86 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_06665 be7d0c1f45ff3dcb4e4af4c68bb3a625 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 270 285 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_06665 be7d0c1f45ff3dcb4e4af4c68bb3a625 400 Pfam PF07690 Major Facilitator Superfamily 20 263 1.9E-39 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_06665 be7d0c1f45ff3dcb4e4af4c68bb3a625 400 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_06665 be7d0c1f45ff3dcb4e4af4c68bb3a625 400 Gene3D G3DSA:1.20.1250.20 9 400 1.2E-90 T 15-10-2018 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 371 2.0E-115 T 15-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 SUPERFAMILY SSF55904 342 488 1.31E-40 T 15-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 SUPERFAMILY SSF53383 7 384 8.25E-99 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 Gene3D G3DSA:3.90.105.10 421 477 1.5E-18 T 15-10-2018 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 Gene3D G3DSA:3.40.640.10 7 284 7.8E-96 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 379 460 4.2E-11 T 15-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 Gene3D G3DSA:3.90.1150.10 313 405 5.0E-7 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_14805 4758544974cc8b9a64e2e7cab3772211 491 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 222 236 - T 15-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 C2I28_17580 f01982a51a719ba1423e1b8829b14176 132 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 13 125 6.5E-24 T 15-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 C2I28_17580 f01982a51a719ba1423e1b8829b14176 132 Pfam PF03061 Thioesterase superfamily 42 118 1.3E-14 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_17580 f01982a51a719ba1423e1b8829b14176 132 SUPERFAMILY SSF54637 7 130 3.28E-31 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_17580 f01982a51a719ba1423e1b8829b14176 132 Gene3D G3DSA:3.10.129.10 1 132 5.7E-40 T 15-10-2018 C2I28_11720 91402bd7adcc1bc2c7e66ed9360279b4 305 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_11720 91402bd7adcc1bc2c7e66ed9360279b4 305 SMART SM00382 34 228 7.6E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11720 91402bd7adcc1bc2c7e66ed9360279b4 305 Pfam PF00005 ABC transporter 26 178 1.6E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_11720 91402bd7adcc1bc2c7e66ed9360279b4 305 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 277 6.4E-9 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_11720 91402bd7adcc1bc2c7e66ed9360279b4 305 Gene3D G3DSA:3.40.50.300 3 303 3.7E-95 T 15-10-2018 C2I28_11720 91402bd7adcc1bc2c7e66ed9360279b4 305 SUPERFAMILY SSF52540 5 250 9.92E-76 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_13290 a09769fa8e9b430beeb5d570350d11d9 237 Pfam PF05076 Suppressor of fused protein (SUFU) 68 233 9.4E-7 T 15-10-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 C2I28_13290 a09769fa8e9b430beeb5d570350d11d9 237 SUPERFAMILY SSF103359 70 237 5.89E-6 T 15-10-2018 IPR037181 Suppressor of fused, N-terminal Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 ProSitePatterns PS00770 Aminotransferases class-IV signature. 233 262 - T 15-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 PIRSF PIRSF006468 1 357 1.7E-134 T 15-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 Pfam PF01063 Amino-transferase class IV 70 312 4.0E-35 T 15-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 44 356 3.0E-125 T 15-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 Gene3D G3DSA:3.20.10.10 171 339 1.5E-137 T 15-10-2018 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 Gene3D G3DSA:3.30.470.10 25 352 1.5E-137 T 15-10-2018 C2I28_20685 539f5d68eeb934324b77b5fd8c3583e4 357 SUPERFAMILY SSF56752 7 353 1.7E-116 T 15-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I28_13365 7607d48ff58c0b3b7d363d92d611fd6e 257 Pfam PF00563 EAL domain 10 233 7.1E-37 T 15-10-2018 IPR001633 EAL domain C2I28_13365 7607d48ff58c0b3b7d363d92d611fd6e 257 SMART SM00052 2 238 1.8E-10 T 15-10-2018 IPR001633 EAL domain C2I28_13365 7607d48ff58c0b3b7d363d92d611fd6e 257 Gene3D G3DSA:3.20.20.450 1 241 7.0E-42 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_13365 7607d48ff58c0b3b7d363d92d611fd6e 257 SUPERFAMILY SSF141868 9 242 8.5E-42 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 Gene3D G3DSA:3.40.309.10 258 451 2.1E-191 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 SUPERFAMILY SSF53720 6 486 5.5E-172 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 Pfam PF00171 Aldehyde dehydrogenase family 16 481 1.4E-178 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 12 479 1.1E-213 T 15-10-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 C2I28_07105 e1f5b3cfcfb2069b56738808cab9ca77 494 Gene3D G3DSA:3.40.605.10 15 476 2.1E-191 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_17585 a1782678b106c71429b5780c8cf7ecd6 208 Gene3D G3DSA:3.90.79.10 1 207 7.1E-35 T 15-10-2018 C2I28_17585 a1782678b106c71429b5780c8cf7ecd6 208 SUPERFAMILY SSF55811 4 153 1.35E-21 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 SUPERFAMILY SSF48179 164 288 9.52E-32 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 1.7E-52 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 Gene3D G3DSA:1.10.1040.10 164 295 4.9E-33 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 SUPERFAMILY SSF51735 3 164 6.57E-50 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 294 5.9E-114 T 15-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 PIRSF PIRSF000103 1 295 2.3E-76 T 15-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 1.8E-31 T 15-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 C2I28_13820 9ab34f260e840e583f8d0346b243fb93 300 Gene3D G3DSA:3.40.50.720 1 163 4.3E-58 T 15-10-2018 C2I28_03700 cf5fcc0ed7217cf2fbf6465e81be3ab6 141 Gene3D G3DSA:3.10.180.10 1 133 1.3E-40 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_03700 cf5fcc0ed7217cf2fbf6465e81be3ab6 141 SUPERFAMILY SSF54593 2 132 2.06E-31 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_03700 cf5fcc0ed7217cf2fbf6465e81be3ab6 141 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 15-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 C2I28_03700 cf5fcc0ed7217cf2fbf6465e81be3ab6 141 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 5 131 5.8E-46 T 15-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 C2I28_03700 cf5fcc0ed7217cf2fbf6465e81be3ab6 141 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 116 5.4E-21 T 15-10-2018 C2I28_07110 41729c40bc9d12e53b4194bf4a883659 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 17 383 2.7E-116 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_07110 41729c40bc9d12e53b4194bf4a883659 400 Gene3D G3DSA:1.20.1090.10 197 396 1.1E-61 T 15-10-2018 C2I28_07110 41729c40bc9d12e53b4194bf4a883659 400 Gene3D G3DSA:3.40.50.1970 3 195 2.1E-58 T 15-10-2018 C2I28_07110 41729c40bc9d12e53b4194bf4a883659 400 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 271 291 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_07110 41729c40bc9d12e53b4194bf4a883659 400 SUPERFAMILY SSF56796 12 394 3.53E-118 T 15-10-2018 C2I28_07110 41729c40bc9d12e53b4194bf4a883659 400 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 184 212 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 2.1E-73 T 15-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 SUPERFAMILY SSF47917 372 499 1.86E-46 T 15-10-2018 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 1.8E-258 T 15-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 PIRSF PIRSF039088 1 501 1.4E-252 T 15-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Gene3D G3DSA:2.40.30.20 1 93 9.5E-38 T 15-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.491 T 15-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 484 1.1E-45 T 15-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 15-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Gene3D G3DSA:1.20.150.20 372 499 6.7E-51 T 15-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 SUPERFAMILY SSF52540 95 370 3.93E-98 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 3.6E-21 T 15-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 Gene3D G3DSA:3.40.50.300 94 371 5.8E-128 T 15-10-2018 C2I28_07325 6896c0ed14ac67e39f1c3128c1f088d0 502 SUPERFAMILY SSF50615 10 94 3.53E-31 T 15-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.9E-6 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.7E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.7E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.7E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.7E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.7E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 Gene3D G3DSA:3.40.50.720 2 249 1.8E-79 T 15-10-2018 C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 244 7.4E-68 T 15-10-2018 C2I28_10100 27bf7c7cb80a6bd25a6b4493b1b59ede 249 SUPERFAMILY SSF51735 3 247 1.0E-80 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03385 02c5faf1ff00ed617056eca510486aa7 191 Pfam PF12822 ECF transporter, substrate-specific component 8 177 4.0E-26 T 15-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 C2I28_03385 02c5faf1ff00ed617056eca510486aa7 191 PIRSF PIRSF037778 3 190 1.1E-46 T 15-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 C2I28_03385 02c5faf1ff00ed617056eca510486aa7 191 Gene3D G3DSA:1.10.1760.20 1 187 6.3E-54 T 15-10-2018 C2I28_21760 59b3d448741385115133af4cce2f5320 293 PIRSF PIRSF030850 1 283 7.2E-72 T 15-10-2018 IPR011396 Uncharacterised conserved protein UCP030850 C2I28_21760 59b3d448741385115133af4cce2f5320 293 Pfam PF13391 HNH endonuclease 175 228 3.3E-9 T 15-10-2018 IPR003615 HNH nuclease C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 Gene3D G3DSA:3.40.50.2300 1 128 1.9E-38 T 15-10-2018 C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 SMART SM00862 149 224 1.5E-24 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 Pfam PF00072 Response regulator receiver domain 4 112 1.0E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 Gene3D G3DSA:1.10.10.10 129 227 5.7E-32 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 SUPERFAMILY SSF52172 1 181 1.33E-41 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 SMART SM00448 2 112 5.0E-45 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_00340 6819f4953e636c51db24f8fb3d53d3b8 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 224 5.2E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 Gene3D G3DSA:1.20.200.10 137 403 3.0E-83 T 15-10-2018 C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 Gene3D G3DSA:1.10.275.10 2 136 3.3E-39 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 1.7E-17 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.7E-17 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 1.7E-17 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 1.7E-17 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 Pfam PF00206 Lyase 12 339 4.6E-71 T 15-10-2018 IPR022761 Fumarate lyase, N-terminal C2I28_19290 4d3aa869c8e339731f28d4f174d44c12 442 SUPERFAMILY SSF48557 2 430 1.01E-95 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.1E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.1E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.1E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 SUPERFAMILY SSF51735 9 251 1.9E-75 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 251 2.3E-54 T 15-10-2018 C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 8.3E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 8.3E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 8.3E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 8.3E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 8.3E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 8.3E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_25045 3170a8196f3dac2d50ce6a711116ad6c 256 Gene3D G3DSA:3.40.50.720 1 254 6.3E-77 T 15-10-2018 C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 4 236 41.907 T 15-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 212 5.0E-53 T 15-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 Gene3D G3DSA:3.40.50.620 15 237 1.6E-74 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 SUPERFAMILY SSF52402 18 200 3.66E-51 T 15-10-2018 C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 PIRSF PIRSF000857 7 237 5.3E-89 T 15-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 46 234 4.1E-77 T 15-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 C2I28_06210 38ad17a8248469478a7b8e027b15685e 237 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 28 236 5.3E-93 T 15-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 C2I28_03065 c8237c223dee20b95ac307e99413d9fd 402 Pfam PF07670 Nucleoside recognition 42 140 4.3E-6 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_03065 c8237c223dee20b95ac307e99413d9fd 402 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 11 386 3.3E-121 T 15-10-2018 IPR014226 Sporulation integral membrane protein YlbJ C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 SMART SM00640 34 452 2.7E-138 T 15-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 34 335 7.6E-105 T 15-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 Gene3D G3DSA:2.60.120.560 349 483 2.8E-28 T 15-10-2018 C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 34 47 - T 15-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 338 478 6.6E-26 T 15-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 SUPERFAMILY SSF75005 25 336 2.04E-113 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 19 463 3.6E-166 T 15-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 Gene3D G3DSA:2.115.10.20 2 348 1.4E-116 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_00875 0b52e157a7b1e62a09f4bcfeba0ef274 491 SUPERFAMILY SSF49899 335 486 1.9E-30 T 15-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily C2I28_07840 337f05518af7e6b8508cc8ca12196a74 159 PIRSF PIRSF004505 1 159 1.2E-54 T 15-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I28_07840 337f05518af7e6b8508cc8ca12196a74 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 8.9E-69 T 15-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I28_07840 337f05518af7e6b8508cc8ca12196a74 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 4.5E-60 T 15-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I28_07840 337f05518af7e6b8508cc8ca12196a74 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 31.228 T 15-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 C2I28_07840 337f05518af7e6b8508cc8ca12196a74 159 Gene3D G3DSA:3.40.1280.10 1 159 9.0E-67 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_07840 337f05518af7e6b8508cc8ca12196a74 159 SUPERFAMILY SSF75217 2 157 2.49E-61 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_02365 65491d5d52e2b748599bf3e94871b06f 263 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 222 248 - T 15-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 C2I28_02365 65491d5d52e2b748599bf3e94871b06f 263 Pfam PF01148 Cytidylyltransferase family 2 262 1.4E-74 T 15-10-2018 C2I28_11555 f19eedd1312fcfcd817f294c449e94b1 274 Gene3D G3DSA:3.40.1160.10 3 242 9.5E-77 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_11555 f19eedd1312fcfcd817f294c449e94b1 274 SUPERFAMILY SSF53633 4 254 9.82E-67 T 15-10-2018 IPR036393 Acetylglutamate kinase-like superfamily C2I28_11555 f19eedd1312fcfcd817f294c449e94b1 274 TIGRFAM TIGR00761 argB: acetylglutamate kinase 7 234 1.2E-81 T 15-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_11555 f19eedd1312fcfcd817f294c449e94b1 274 Hamap MF_00082 Acetylglutamate kinase [argB]. 4 252 45.729 T 15-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_11555 f19eedd1312fcfcd817f294c449e94b1 274 Pfam PF00696 Amino acid kinase family 5 227 4.2E-44 T 15-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 C2I28_11555 f19eedd1312fcfcd817f294c449e94b1 274 PIRSF PIRSF000728 1 251 2.7E-91 T 15-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 Gene3D G3DSA:1.10.8.870 419 549 1.4E-44 T 15-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 370 380 - T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 Gene3D G3DSA:3.50.50.60 17 378 1.2E-137 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 19 31 5.2E-30 T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 48 60 5.2E-30 T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 93 105 5.2E-30 T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 335 341 5.2E-30 T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 42 5.2E-30 T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 365 377 5.2E-30 T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 24 41 - T 15-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 Pfam PF01266 FAD dependent oxidoreductase 20 349 6.7E-56 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 Gene3D G3DSA:3.30.9.10 101 342 1.2E-137 T 15-10-2018 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 401 529 7.6E-25 T 15-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 SUPERFAMILY SSF54373 248 341 2.55E-10 T 15-10-2018 C2I28_10820 8ee9a921dd138efec905e397b69dd635 559 SUPERFAMILY SSF51905 17 236 1.3E-34 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 SUPERFAMILY SSF46785 268 395 1.08E-12 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 SUPERFAMILY SSF75217 106 253 4.4E-38 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 Gene3D G3DSA:3.30.1330.30 6 98 6.4E-10 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 SUPERFAMILY SSF55315 8 98 8.47E-11 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 Pfam PF00588 SpoU rRNA Methylase family 108 249 6.5E-36 T 15-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 Gene3D G3DSA:1.10.10.10 254 396 4.3E-13 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26460 a4cae02b0db54d179c1d4af6d80ce015 397 Gene3D G3DSA:3.40.1280.10 99 253 5.6E-44 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_03570 241a34d741c9dc271cd92e39f0422716 183 Gene3D G3DSA:3.90.79.10 5 180 3.9E-55 T 15-10-2018 C2I28_03570 241a34d741c9dc271cd92e39f0422716 183 SUPERFAMILY SSF55811 8 177 4.33E-50 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_03570 241a34d741c9dc271cd92e39f0422716 183 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 15-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I28_03570 241a34d741c9dc271cd92e39f0422716 183 Pfam PF00293 NUDIX domain 42 157 1.1E-17 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_22150 d37969b4001b49e988319b55626027da 328 Gene3D G3DSA:3.60.15.10 2 261 1.6E-51 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_22150 d37969b4001b49e988319b55626027da 328 SMART SM00849 20 234 2.5E-22 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_22150 d37969b4001b49e988319b55626027da 328 SUPERFAMILY SSF56281 12 320 1.83E-47 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_22150 d37969b4001b49e988319b55626027da 328 Pfam PF00753 Metallo-beta-lactamase superfamily 19 234 3.0E-18 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_09825 5020e98b0e79a82058549ae137022cf6 434 Gene3D G3DSA:1.25.40.680 240 400 1.6E-50 T 15-10-2018 C2I28_09825 5020e98b0e79a82058549ae137022cf6 434 Gene3D G3DSA:1.10.510.10 1 217 1.4E-81 T 15-10-2018 C2I28_09825 5020e98b0e79a82058549ae137022cf6 434 TIGRFAM TIGR03926 T7_EssB: type VII secretion protein EssB 8 382 1.5E-119 T 15-10-2018 IPR018778 Type VII secretion system EssB C2I28_09825 5020e98b0e79a82058549ae137022cf6 434 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 28 382 3.0E-119 T 15-10-2018 IPR018778 Type VII secretion system EssB C2I28_17845 091795ba208e43a56c78da57107954bf 309 SUPERFAMILY SSF48179 178 301 9.52E-28 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_17845 091795ba208e43a56c78da57107954bf 309 Gene3D G3DSA:3.40.50.720 1 173 4.6E-53 T 15-10-2018 C2I28_17845 091795ba208e43a56c78da57107954bf 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 302 2.7E-72 T 15-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 C2I28_17845 091795ba208e43a56c78da57107954bf 309 SUPERFAMILY SSF51735 1 151 1.91E-14 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17845 091795ba208e43a56c78da57107954bf 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 300 4.1E-24 T 15-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain C2I28_17845 091795ba208e43a56c78da57107954bf 309 Gene3D G3DSA:1.10.1040.10 177 301 3.0E-31 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_17845 091795ba208e43a56c78da57107954bf 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 151 4.2E-39 T 15-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain C2I28_11790 0d32b509ce8f682e230101e38b5cd0f3 283 Pfam PF13743 Thioredoxin 16 207 8.3E-77 T 15-10-2018 C2I28_11790 0d32b509ce8f682e230101e38b5cd0f3 283 Gene3D G3DSA:3.40.30.10 18 206 9.7E-37 T 15-10-2018 C2I28_11790 0d32b509ce8f682e230101e38b5cd0f3 283 SUPERFAMILY SSF52833 11 215 2.65E-30 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_11790 0d32b509ce8f682e230101e38b5cd0f3 283 Gene3D G3DSA:1.10.472.60 53 177 9.7E-37 T 15-10-2018 C2I28_01230 9dd43dd526b8d7866078d53c69b9ce46 300 SUPERFAMILY SSF161098 60 289 4.97E-62 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_01230 9dd43dd526b8d7866078d53c69b9ce46 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 295 5.2E-22 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_01230 9dd43dd526b8d7866078d53c69b9ce46 300 Gene3D G3DSA:1.10.3720.10 56 299 2.7E-72 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_21380 546542a5352350fa63c41e0b10776b31 396 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 377 6.2E-123 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_21380 546542a5352350fa63c41e0b10776b31 396 Gene3D G3DSA:3.40.50.1970 2 184 3.1E-56 T 15-10-2018 C2I28_21380 546542a5352350fa63c41e0b10776b31 396 SUPERFAMILY SSF56796 6 385 1.44E-119 T 15-10-2018 C2I28_21380 546542a5352350fa63c41e0b10776b31 396 Gene3D G3DSA:1.20.1090.10 185 386 3.3E-65 T 15-10-2018 C2I28_21380 546542a5352350fa63c41e0b10776b31 396 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_01225 cc9b9c1260469b5368aa2fdd22cad8b3 273 SUPERFAMILY SSF161098 2 272 9.94E-76 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_01225 cc9b9c1260469b5368aa2fdd22cad8b3 273 Gene3D G3DSA:1.10.3720.10 1 265 1.1E-72 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_01225 cc9b9c1260469b5368aa2fdd22cad8b3 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 267 5.2E-24 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_05160 89811a03fd07e03996ddc59764eac87b 149 Pfam PF03061 Thioesterase superfamily 33 118 8.1E-14 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_05160 89811a03fd07e03996ddc59764eac87b 149 SUPERFAMILY SSF54637 16 146 3.05E-35 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_05160 89811a03fd07e03996ddc59764eac87b 149 Gene3D G3DSA:3.10.129.10 6 149 2.0E-34 T 15-10-2018 C2I28_23345 42461d806de2834bd26ea8255e37de38 255 Gene3D G3DSA:3.40.50.150 18 255 2.5E-59 T 15-10-2018 C2I28_23345 42461d806de2834bd26ea8255e37de38 255 SUPERFAMILY SSF53335 26 206 2.89E-38 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_23345 42461d806de2834bd26ea8255e37de38 255 Pfam PF13847 Methyltransferase domain 34 132 1.5E-21 T 15-10-2018 IPR025714 Methyltransferase domain C2I28_10030 e6b98bf433121d5e5037223a1c6bb56c 447 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_10030 e6b98bf433121d5e5037223a1c6bb56c 447 Gene3D G3DSA:1.20.1740.10 5 447 4.7E-62 T 15-10-2018 C2I28_10030 e6b98bf433121d5e5037223a1c6bb56c 447 Pfam PF00324 Amino acid permease 14 436 1.5E-102 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_10030 e6b98bf433121d5e5037223a1c6bb56c 447 PIRSF PIRSF006060 1 447 2.8E-67 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_21275 40fa07e5d06b45864032f03c8d31540c 318 Pfam PF03547 Membrane transport protein 166 313 1.3E-21 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_21275 40fa07e5d06b45864032f03c8d31540c 318 Pfam PF03547 Membrane transport protein 10 161 1.3E-25 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_23520 b48bff9841ffcd9594e6be4e19107e03 150 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 139 1.1E-35 T 15-10-2018 IPR006750 Putative inner membrane exporter, YdcZ C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 Pfam PF00245 Alkaline phosphatase 41 462 1.2E-90 T 15-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 PRINTS PR00113 Alkaline phosphatase signature 182 192 3.0E-30 T 15-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 PRINTS PR00113 Alkaline phosphatase signature 259 288 3.0E-30 T 15-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 PRINTS PR00113 Alkaline phosphatase signature 138 158 3.0E-30 T 15-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 PRINTS PR00113 Alkaline phosphatase signature 40 60 3.0E-30 T 15-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 SUPERFAMILY SSF53649 29 471 1.1E-113 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 SUPERFAMILY SSF55383 481 540 5.75E-5 T 15-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 Gene3D G3DSA:3.40.720.10 41 441 2.2E-127 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 Gene3D G3DSA:1.10.1200.140 380 439 2.2E-127 T 15-10-2018 C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 Pfam PF07833 Copper amine oxidase N-terminal domain 472 540 1.5E-5 T 15-10-2018 IPR012854 Copper amine oxidase-like, N-terminal C2I28_14170 f51cba685432970eac7bd10d6c6a4e9f 551 SMART SM00098 41 465 4.8E-86 T 15-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 C2I28_12845 4aacfcbf7d3e75ec4cf905d71dde3973 268 SUPERFAMILY SSF161098 2 268 1.03E-66 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_12845 4aacfcbf7d3e75ec4cf905d71dde3973 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 262 4.3E-17 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_12845 4aacfcbf7d3e75ec4cf905d71dde3973 268 Gene3D G3DSA:1.10.3720.10 1 260 4.0E-59 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18365 eae6cd7956b5a80897afef6e5122a5c7 290 SUPERFAMILY SSF52091 164 269 5.3E-17 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_18365 eae6cd7956b5a80897afef6e5122a5c7 290 Gene3D G3DSA:3.30.750.24 158 274 2.7E-35 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_18365 eae6cd7956b5a80897afef6e5122a5c7 290 Pfam PF01740 STAS domain 164 260 4.6E-13 T 15-10-2018 IPR002645 STAS domain C2I28_20775 2ba82dd7020cf332bb28bcd3716c4d05 449 PIRSF PIRSF006060 1 448 1.3E-70 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_20775 2ba82dd7020cf332bb28bcd3716c4d05 449 Gene3D G3DSA:1.20.1740.10 2 443 2.0E-67 T 15-10-2018 C2I28_20775 2ba82dd7020cf332bb28bcd3716c4d05 449 Pfam PF13520 Amino acid permease 11 394 1.5E-46 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_20775 2ba82dd7020cf332bb28bcd3716c4d05 449 TIGRFAM TIGR00908 2A0305: ethanolamine permease 2 438 4.9E-142 T 15-10-2018 IPR004757 Ethanolamine permease C2I28_02465 3218d17b190f8cd8d2198d431ba302fd 120 Pfam PF00072 Response regulator receiver domain 5 115 2.7E-35 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_02465 3218d17b190f8cd8d2198d431ba302fd 120 Gene3D G3DSA:3.40.50.2300 2 120 5.4E-41 T 15-10-2018 C2I28_02465 3218d17b190f8cd8d2198d431ba302fd 120 SMART SM00448 3 115 7.4E-42 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_02465 3218d17b190f8cd8d2198d431ba302fd 120 SUPERFAMILY SSF52172 3 119 1.11E-41 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 402 1.0E-134 T 15-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 285 1.4E-24 T 15-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 SUPERFAMILY SSF51735 3 192 1.14E-44 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 SUPERFAMILY SSF48179 198 290 1.53E-26 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 SUPERFAMILY SSF52413 304 415 1.28E-29 T 15-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 SMART SM00984 310 406 2.1E-34 T 15-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 Gene3D G3DSA:3.40.50.720 197 426 1.9E-71 T 15-10-2018 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 310 405 1.9E-28 T 15-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 Gene3D G3DSA:3.40.50.720 1 196 6.6E-67 T 15-10-2018 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 PIRSF PIRSF000124 3 421 3.0E-81 T 15-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 PIRSF PIRSF500136 1 421 1.3E-152 T 15-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 C2I28_07220 ebbdc9903667bed1496133fabb260a42 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 178 4.9E-52 T 15-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 C2I28_26320 7181e343757c14e8dacda7fd6e2812d6 186 Gene3D G3DSA:1.10.150.240 16 80 1.1E-26 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_26320 7181e343757c14e8dacda7fd6e2812d6 186 SUPERFAMILY SSF56784 1 181 5.87E-29 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_26320 7181e343757c14e8dacda7fd6e2812d6 186 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 169 4.4E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_26320 7181e343757c14e8dacda7fd6e2812d6 186 Gene3D G3DSA:3.40.50.1000 5 183 1.1E-26 T 15-10-2018 IPR023214 HAD superfamily C2I28_26320 7181e343757c14e8dacda7fd6e2812d6 186 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 7.8E-32 T 15-10-2018 C2I28_10980 1826a811f538a70748e3b4d0d85e17ee 359 Gene3D G3DSA:3.30.470.20 219 349 9.5E-6 T 15-10-2018 C2I28_10980 1826a811f538a70748e3b4d0d85e17ee 359 Pfam PF14398 YheC/D like ATP-grasp 98 350 7.3E-67 T 15-10-2018 IPR026838 Endospore coat-associated protein YheC/D C2I28_10980 1826a811f538a70748e3b4d0d85e17ee 359 SUPERFAMILY SSF56059 122 330 4.42E-15 T 15-10-2018 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 715 1.8E-186 T 15-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 SMART SM00436 130 225 3.3E-33 T 15-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Pfam PF13342 C-terminal repeat of topoisomerase 659 716 1.7E-16 T 15-10-2018 IPR025589 Topoisomerase C-terminal repeat C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 SUPERFAMILY SSF56712 1 601 1.7E-176 T 15-10-2018 IPR023405 DNA topoisomerase, type IA, core domain C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 SMART SM00437 273 551 1.7E-83 T 15-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Gene3D G3DSA:1.10.460.10 164 596 1.6E-153 T 15-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 15-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Gene3D G3DSA:2.70.20.10 219 481 1.6E-153 T 15-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Pfam PF01751 Toprim domain 3 138 3.9E-11 T 15-10-2018 IPR006171 TOPRIM domain C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Pfam PF01131 DNA topoisomerase 157 586 2.1E-123 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 SMART SM00493 1 130 7.8E-12 T 15-10-2018 IPR006171 TOPRIM domain C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Gene3D G3DSA:3.40.50.140 1 157 5.7E-52 T 15-10-2018 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 Gene3D G3DSA:1.10.290.10 282 411 1.6E-153 T 15-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 7.2E-26 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 7.2E-26 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 7.2E-26 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 7.2E-26 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_17575 4a0c22d73728a92d21ac612c60650059 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 7.2E-26 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 Pfam PF09339 IclR helix-turn-helix domain 6 56 1.5E-19 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 SUPERFAMILY SSF55781 64 249 7.85E-50 T 15-10-2018 C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 SMART SM00346 4 94 4.0E-33 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 Pfam PF01614 Bacterial transcriptional regulator 122 246 1.9E-39 T 15-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 Gene3D G3DSA:3.30.450.40 78 252 1.9E-57 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 Gene3D G3DSA:1.10.10.10 3 77 1.0E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25750 5c284cbcdd1d4a3867002c033749a803 254 SUPERFAMILY SSF46785 4 78 3.0E-18 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_08495 f85a0e41ac05754738c0b68c5dca1f81 119 Gene3D G3DSA:3.30.1130.10 1 119 1.8E-45 T 15-10-2018 C2I28_08495 f85a0e41ac05754738c0b68c5dca1f81 119 SMART SM00905 4 117 4.6E-49 T 15-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I28_08495 f85a0e41ac05754738c0b68c5dca1f81 119 SUPERFAMILY SSF55620 2 119 2.27E-39 T 15-10-2018 C2I28_08495 f85a0e41ac05754738c0b68c5dca1f81 119 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 5.3E-38 T 15-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I28_08495 f85a0e41ac05754738c0b68c5dca1f81 119 Pfam PF02152 Dihydroneopterin aldolase 4 115 2.2E-36 T 15-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I28_08495 f85a0e41ac05754738c0b68c5dca1f81 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 4.5E-42 T 15-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 C2I28_06745 528499cf556ff85dbe18a3f7d8539647 189 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 189 21.327 T 15-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 C2I28_06745 528499cf556ff85dbe18a3f7d8539647 189 SUPERFAMILY SSF53448 1 187 3.13E-31 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06745 528499cf556ff85dbe18a3f7d8539647 189 Pfam PF12804 MobA-like NTP transferase domain 5 158 8.6E-34 T 15-10-2018 IPR025877 MobA-like NTP transferase C2I28_06745 528499cf556ff85dbe18a3f7d8539647 189 Gene3D G3DSA:3.90.550.10 1 189 4.9E-46 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 SUPERFAMILY SSF46785 5 77 3.74E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 Gene3D G3DSA:1.20.120.530 85 229 7.3E-31 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 SMART SM00895 97 222 3.5E-23 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.5E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.5E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 4.8E-20 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 SMART SM00345 14 73 1.0E-20 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 SUPERFAMILY SSF48008 93 227 1.75E-26 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 Gene3D G3DSA:1.10.10.10 1 73 2.0E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25445 7b47956e38e7ee533753df7e5fc26475 231 Pfam PF07729 FCD domain 97 221 4.1E-24 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SMART SM00028 35 68 0.0038 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SMART SM00028 1 34 0.85 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SMART SM00028 69 102 1.1 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SMART SM00028 171 204 6.1E-7 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SMART SM00028 103 136 0.0061 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SMART SM00028 137 170 13.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 Pfam PF13181 Tetratricopeptide repeat 69 97 0.0015 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 SUPERFAMILY SSF81901 5 212 1.02E-39 T 15-10-2018 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 Gene3D G3DSA:1.25.40.10 24 219 1.4E-52 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 Pfam PF00515 Tetratricopeptide repeat 171 204 1.7E-7 T 15-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 Pfam PF13414 TPR repeat 10 46 1.4E-7 T 15-10-2018 C2I28_04630 bac53b86856bc0a6b129e1008a467c6d 219 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 101 162 7.4E-7 T 15-10-2018 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 477 570 4.6E-11 T 15-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 SUPERFAMILY SSF52518 197 458 1.73E-73 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 SUPERFAMILY SSF53323 1 221 3.01E-44 T 15-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 SUPERFAMILY SSF52922 474 578 1.28E-23 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 Gene3D G3DSA:3.40.920.10 1 186 9.7E-31 T 15-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 211 451 2.3E-61 T 15-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 Gene3D G3DSA:3.40.50.970 187 387 1.6E-76 T 15-10-2018 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 175 9.7E-41 T 15-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 573 1.3E-215 T 15-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 C2I28_02135 bacae13636ee9ad443c97cf8ed974ec5 585 Gene3D G3DSA:3.40.50.920 468 580 4.0E-29 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_23895 7459ec4850c32d2c7b098cff91e751d7 160 Pfam PF10002 Predicted membrane protein (DUF2243) 22 149 1.7E-46 T 15-10-2018 IPR018719 Protein of unknown function DUF2243, membrane C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 Pfam PF00271 Helicase conserved C-terminal domain 291 393 2.3E-13 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 SUPERFAMILY SSF52540 75 450 3.49E-34 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 SUPERFAMILY SSF52540 32 245 2.32E-44 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 Gene3D G3DSA:3.40.50.300 273 415 1.8E-20 T 15-10-2018 C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 Pfam PF09369 Domain of unknown function (DUF1998) 655 733 8.2E-21 T 15-10-2018 IPR018973 DEAD/DEAH-box helicase, putative C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 Pfam PF00270 DEAD/DEAH box helicase 63 234 5.9E-29 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 SMART SM00490 307 394 6.6E-14 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 SMART SM00487 56 260 1.5E-35 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_15165 f5e4ba51d24ce7de995c8f8c79808eb0 756 Gene3D G3DSA:3.40.50.300 27 250 5.1E-50 T 15-10-2018 C2I28_12830 4763191c8a66e92f77841e7dbba68cab 203 Gene3D G3DSA:2.30.110.10 2 203 1.4E-68 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_12830 4763191c8a66e92f77841e7dbba68cab 203 SUPERFAMILY SSF50475 10 198 8.34E-47 T 15-10-2018 C2I28_12830 4763191c8a66e92f77841e7dbba68cab 203 SMART SM00903 20 174 1.2E-24 T 15-10-2018 IPR002563 Flavin reductase like domain GO:0010181 C2I28_12830 4763191c8a66e92f77841e7dbba68cab 203 Pfam PF01613 Flavin reductase like domain 23 167 4.8E-24 T 15-10-2018 IPR002563 Flavin reductase like domain GO:0010181 C2I28_15810 3f7211b3bbfbaedb8276d5a0c206782c 221 Pfam PF01965 DJ-1/PfpI family 27 218 3.8E-16 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_15810 3f7211b3bbfbaedb8276d5a0c206782c 221 SUPERFAMILY SSF52317 1 219 4.4E-65 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_15810 3f7211b3bbfbaedb8276d5a0c206782c 221 Gene3D G3DSA:3.40.50.880 1 221 2.2E-76 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SUPERFAMILY SSF50249 628 709 7.26E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 62 710 3.3E-256 T 15-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Gene3D G3DSA:2.40.50.140 631 742 3.4E-28 T 15-10-2018 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SUPERFAMILY SSF50249 57 137 5.92E-19 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SMART SM00955 250 580 1.6E-184 T 15-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Gene3D G3DSA:2.40.50.140 137 205 2.0E-9 T 15-10-2018 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Gene3D G3DSA:2.40.50.140 62 136 3.6E-19 T 15-10-2018 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 TIGRFAM TIGR02063 RNase_R: ribonuclease R 9 710 3.5E-289 T 15-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SMART SM00357 140 204 8.3E-8 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SMART SM00357 75 135 5.7E-12 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Pfam PF00773 RNB domain 250 578 4.3E-115 T 15-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Pfam PF08206 Ribonuclease B OB domain 149 203 4.5E-8 T 15-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Pfam PF08206 Ribonuclease B OB domain 76 134 1.2E-21 T 15-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Hamap MF_01895 Ribonuclease R [rnr]. 27 710 61.845 T 15-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 Pfam PF00575 S1 RNA binding domain 627 707 1.8E-17 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SMART SM00316 628 710 3.9E-20 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SUPERFAMILY SSF50249 210 627 1.14E-148 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 ProSitePatterns PS01175 Ribonuclease II family signature. 547 571 - T 15-10-2018 IPR022966 Ribonuclease II/R, conserved site C2I28_06795 af5a46b37728095e46eae65c336c7f0c 780 SUPERFAMILY SSF50249 128 227 4.05E-20 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 SUPERFAMILY SSF46785 5 93 2.72E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 Pfam PF12840 Helix-turn-helix domain 17 72 7.3E-14 T 15-10-2018 C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 2.3E-14 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 2.3E-14 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 2.3E-14 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 SMART SM00418 16 94 1.9E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23295 b9c3759bf818ea1a9b44154d5c5c26c4 104 Gene3D G3DSA:1.10.10.10 2 95 3.5E-23 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_08415 91b5e21267a772820b35ae7e18f2f2da 123 Pfam PF04977 Septum formation initiator 47 122 6.9E-18 T 15-10-2018 IPR007060 Septum formation initiator FtsL/DivIC C2I28_06015 9f62d5bf4eccaf4ef8fd49195d614ebe 250 SUPERFAMILY SSF57716 92 124 2.46E-6 T 15-10-2018 C2I28_06015 9f62d5bf4eccaf4ef8fd49195d614ebe 250 SUPERFAMILY SSF109635 3 90 4.45E-12 T 15-10-2018 IPR037187 DksA, N-terminal domain superfamily C2I28_06015 9f62d5bf4eccaf4ef8fd49195d614ebe 250 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 6 165 1.1E-60 T 15-10-2018 IPR014240 Regulatory protein, YteA family C2I28_06015 9f62d5bf4eccaf4ef8fd49195d614ebe 250 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 91 118 1.2E-8 T 15-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 C2I28_06015 9f62d5bf4eccaf4ef8fd49195d614ebe 250 Gene3D G3DSA:1.20.120.910 1 129 1.0E-28 T 15-10-2018 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 SUPERFAMILY SSF53901 267 387 1.92E-43 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 386 6.0E-142 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 Pfam PF00108 Thiolase, N-terminal domain 5 257 3.2E-79 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 ProSitePatterns PS00099 Thiolases active site. 369 382 - T 15-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 ProSitePatterns PS00737 Thiolases signature 2. 334 350 - T 15-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 Gene3D G3DSA:3.40.47.10 124 385 4.5E-149 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 Pfam PF02803 Thiolase, C-terminal domain 266 387 2.1E-47 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 PIRSF PIRSF000429 1 387 2.5E-131 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 Gene3D G3DSA:3.40.47.10 6 271 4.5E-149 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_17250 2f1fe3c6f479f43d0b2c19e359012519 387 SUPERFAMILY SSF53901 5 264 2.67E-75 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_08585 11453aeac7bc825c0535f2232288f9f7 141 Pfam PF00636 Ribonuclease III domain 15 112 4.9E-16 T 15-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I28_08585 11453aeac7bc825c0535f2232288f9f7 141 PIRSF PIRSF005520 1 135 8.3E-52 T 15-10-2018 IPR008226 Mini-ribonuclease 3 family C2I28_08585 11453aeac7bc825c0535f2232288f9f7 141 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 5 131 30.503 T 15-10-2018 IPR008226 Mini-ribonuclease 3 family C2I28_08585 11453aeac7bc825c0535f2232288f9f7 141 SUPERFAMILY SSF69065 7 129 5.06E-42 T 15-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I28_08585 11453aeac7bc825c0535f2232288f9f7 141 Gene3D G3DSA:1.10.1520.10 2 139 1.9E-49 T 15-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 C2I28_08585 11453aeac7bc825c0535f2232288f9f7 141 SMART SM00535 3 132 8.9E-6 T 15-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 Pfam PF00231 ATP synthase 3 284 1.6E-101 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 SUPERFAMILY SSF52943 2 284 1.7E-94 T 15-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 284 1.3E-112 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.5E-40 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 PRINTS PR00126 ATP synthase gamma subunit signature 262 283 1.5E-40 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.5E-40 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 PRINTS PR00126 ATP synthase gamma subunit signature 231 250 1.5E-40 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 270 283 - T 15-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 Gene3D G3DSA:3.40.1380.10 61 203 4.8E-103 T 15-10-2018 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 Gene3D G3DSA:1.10.287.80 6 280 4.8E-103 T 15-10-2018 C2I28_07320 5f7b6854854e0ad3baa830849e9ac22f 285 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 284 36.584 T 15-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 Pfam PF00480 ROK family 84 373 2.1E-54 T 15-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 SUPERFAMILY SSF46785 8 73 2.54E-15 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 Gene3D G3DSA:3.30.420.40 81 374 6.5E-87 T 15-10-2018 C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 SUPERFAMILY SSF53067 79 198 3.42E-20 T 15-10-2018 C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 Gene3D G3DSA:3.30.420.40 203 355 6.5E-87 T 15-10-2018 C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 ProSitePatterns PS01125 ROK family signature. 212 239 - T 15-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 Gene3D G3DSA:1.10.10.10 11 76 9.9E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25060 32f3c688775230f3a9a3980c1666b406 395 SUPERFAMILY SSF53067 205 378 5.55E-38 T 15-10-2018 C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 SUPERFAMILY SSF74650 9 250 4.08E-44 T 15-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Pfam PF01055 Glycosyl hydrolases family 31 245 690 4.2E-120 T 15-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Gene3D G3DSA:2.60.40.1760 7 249 8.1E-40 T 15-10-2018 C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Pfam PF13802 Galactose mutarotase-like 151 219 1.1E-19 T 15-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 SUPERFAMILY SSF51445 253 596 6.95E-68 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Pfam PF17137 Domain of unknown function (DUF5110) 712 771 3.0E-10 T 15-10-2018 IPR033403 Domain of unknown function DUF5110 C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 SUPERFAMILY SSF51011 604 685 3.38E-19 T 15-10-2018 C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Gene3D G3DSA:2.60.40.1180 687 796 1.9E-12 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Gene3D G3DSA:2.60.40.1180 637 686 6.2E-12 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_25015 0af23bf1cc3ffdc1bb737021d16c7957 801 Gene3D G3DSA:3.20.20.80 251 634 6.6E-115 T 15-10-2018 C2I28_16075 d4003905c8beaa661c56029e8001c41a 254 Gene3D G3DSA:3.40.50.150 34 191 1.6E-12 T 15-10-2018 C2I28_16075 d4003905c8beaa661c56029e8001c41a 254 SUPERFAMILY SSF53335 49 188 4.56E-13 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_16075 d4003905c8beaa661c56029e8001c41a 254 Pfam PF08241 Methyltransferase domain 56 142 6.2E-7 T 15-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I28_13095 2ae6c367cfd5d06d25d017baf3f0d3ad 75 Pfam PF12645 Helix-turn-helix domain 5 61 3.8E-8 T 15-10-2018 IPR024760 Helix-turn-helix, conjugative transposon-like C2I28_13095 2ae6c367cfd5d06d25d017baf3f0d3ad 75 Gene3D G3DSA:1.10.1740.10 2 71 2.7E-6 T 15-10-2018 C2I28_13095 2ae6c367cfd5d06d25d017baf3f0d3ad 75 SUPERFAMILY SSF88946 3 69 7.65E-7 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 23 269 7.9E-113 T 15-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 15-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 23 268 1.5E-119 T 15-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 Gene3D G3DSA:3.40.50.1580 1 271 1.1E-119 T 15-10-2018 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 Pfam PF01048 Phosphorylase superfamily 22 268 8.1E-58 T 15-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 PIRSF PIRSF000477 1 271 1.3E-121 T 15-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 C2I28_03540 4a940a9241b0e8c6f264de3af0782f3e 276 SUPERFAMILY SSF53167 4 274 1.28E-103 T 15-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I28_05250 ccd14abe15edb081c1cbf496436742c5 185 Pfam PF02674 Colicin V production protein 6 163 5.1E-31 T 15-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 C2I28_14400 dc60ddf52f55fd1610b7293e30cd9091 399 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 389 8.0E-95 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_14400 dc60ddf52f55fd1610b7293e30cd9091 399 Gene3D G3DSA:3.30.300.210 233 391 1.6E-40 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_14400 dc60ddf52f55fd1610b7293e30cd9091 399 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 218 387 2.2E-41 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_02955 6ea5324102abb2eee9ca5d15f8ca1f9b 366 Pfam PF01098 Cell cycle protein 12 365 2.5E-129 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02955 6ea5324102abb2eee9ca5d15f8ca1f9b 366 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 363 6.2E-133 T 15-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02955 6ea5324102abb2eee9ca5d15f8ca1f9b 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 15-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_02955 6ea5324102abb2eee9ca5d15f8ca1f9b 366 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 362 9.0E-180 T 15-10-2018 IPR013438 Sporulation stage V, protein E C2I28_02955 6ea5324102abb2eee9ca5d15f8ca1f9b 366 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 9 362 4.7E-102 T 15-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_25845 92adbfd7d0607fd7873aabb0c5f583b2 263 Pfam PF04909 Amidohydrolase 3 260 3.7E-19 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_25845 92adbfd7d0607fd7873aabb0c5f583b2 263 Gene3D G3DSA:3.20.20.140 1 263 1.6E-67 T 15-10-2018 C2I28_25845 92adbfd7d0607fd7873aabb0c5f583b2 263 SUPERFAMILY SSF51556 1 262 1.32E-34 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_05845 55a703929223a5c55fcc0eb0cda9a0f9 174 Gene3D G3DSA:1.20.144.10 52 170 4.6E-20 T 15-10-2018 C2I28_05845 55a703929223a5c55fcc0eb0cda9a0f9 174 SMART SM00014 61 169 1.5E-19 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_05845 55a703929223a5c55fcc0eb0cda9a0f9 174 SUPERFAMILY SSF48317 10 172 6.93E-39 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_05845 55a703929223a5c55fcc0eb0cda9a0f9 174 Pfam PF01569 PAP2 superfamily 64 171 3.1E-22 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_06505 f9f2b0ac7950e525245b81d23e05c543 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 5.6E-23 T 15-10-2018 IPR014931 Protein of unknown function DUF1805 C2I28_06505 f9f2b0ac7950e525245b81d23e05c543 100 SUPERFAMILY SSF102891 1 99 4.18E-31 T 15-10-2018 IPR036493 Hypothetical protein YunC superfamily C2I28_06505 f9f2b0ac7950e525245b81d23e05c543 100 Gene3D G3DSA:3.30.1980.10 1 100 5.8E-23 T 15-10-2018 IPR036493 Hypothetical protein YunC superfamily C2I28_17975 db969e918af27a3d15ee8f075101b5a7 458 Gene3D G3DSA:3.50.30.30 99 225 1.5E-135 T 15-10-2018 C2I28_17975 db969e918af27a3d15ee8f075101b5a7 458 Pfam PF02225 PA domain 123 207 5.9E-18 T 15-10-2018 IPR003137 PA domain C2I28_17975 db969e918af27a3d15ee8f075101b5a7 458 SUPERFAMILY SSF52025 107 213 5.49E-23 T 15-10-2018 C2I28_17975 db969e918af27a3d15ee8f075101b5a7 458 Gene3D G3DSA:3.40.630.10 59 422 1.5E-135 T 15-10-2018 C2I28_17975 db969e918af27a3d15ee8f075101b5a7 458 Pfam PF04389 Peptidase family M28 246 425 3.6E-45 T 15-10-2018 IPR007484 Peptidase M28 C2I28_17975 db969e918af27a3d15ee8f075101b5a7 458 SUPERFAMILY SSF53187 33 429 2.78E-61 T 15-10-2018 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 SUPERFAMILY SSF47323 644 916 1.46E-80 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 833 0.0 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Pfam PF06827 Zinc finger found in FPG and IleRS 884 913 3.4E-9 T 15-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Gene3D G3DSA:3.40.50.620 24 621 2.3E-264 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Gene3D G3DSA:3.90.740.10 194 398 2.3E-264 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 633 1.8E-221 T 15-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 7.6E-32 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 7.6E-32 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 7.6E-32 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 7.6E-32 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 7.6E-32 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 915 21.271 T 15-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Pfam PF08264 Anticodon-binding domain of tRNA 677 830 1.0E-28 T 15-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 Gene3D G3DSA:1.10.730.20 632 917 1.5E-104 T 15-10-2018 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 SUPERFAMILY SSF52374 1 640 1.04E-154 T 15-10-2018 C2I28_02880 b5e5eeeea8271d36dbcc43323655a994 921 SUPERFAMILY SSF50677 203 393 4.19E-63 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_12625 8a48754e56a9ab58776d53258071a3b2 81 Gene3D G3DSA:3.30.70.20 2 81 3.2E-31 T 15-10-2018 C2I28_12625 8a48754e56a9ab58776d53258071a3b2 81 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 68 2.1E-19 T 15-10-2018 C2I28_12625 8a48754e56a9ab58776d53258071a3b2 81 SUPERFAMILY SSF54862 3 71 3.01E-10 T 15-10-2018 C2I28_12625 8a48754e56a9ab58776d53258071a3b2 81 PRINTS PR00352 3Fe-4S ferredoxin signature 17 27 1.3E-6 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_12625 8a48754e56a9ab58776d53258071a3b2 81 PRINTS PR00352 3Fe-4S ferredoxin signature 54 66 1.3E-6 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_12625 8a48754e56a9ab58776d53258071a3b2 81 PRINTS PR00352 3Fe-4S ferredoxin signature 6 17 1.3E-6 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 621 9.9E-186 T 15-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 SUPERFAMILY SSF52540 3 171 7.31E-31 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 Pfam PF07670 Nucleoside recognition 501 624 1.6E-32 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 Pfam PF07670 Nucleoside recognition 340 434 5.8E-15 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 Pfam PF02421 Ferrous iron transport protein B 3 154 1.9E-54 T 15-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 Gene3D G3DSA:3.40.50.300 1 190 1.7E-37 T 15-10-2018 C2I28_12660 b53f79937b3e77909bc8007eecb74b37 656 Pfam PF07664 Ferrous iron transport protein B C terminus 444 496 8.5E-20 T 15-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 Pfam PF00202 Aminotransferase class-III 30 444 1.6E-116 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 Gene3D G3DSA:3.40.640.10 66 346 4.3E-163 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 PIRSF PIRSF000521 29 450 2.6E-39 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 16 447 1.2E-162 T 15-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 4 450 51.756 T 15-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 Gene3D G3DSA:3.90.1150.10 12 447 4.3E-163 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 SUPERFAMILY SSF53383 11 449 2.42E-129 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_12330 b5c6f63ffd1faaf71b55ad931cfd1a0c 457 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_22220 b6d0c6e1b9b113fbd1f1824292f54886 345 SMART SM00052 97 337 6.7E-28 T 15-10-2018 IPR001633 EAL domain C2I28_22220 b6d0c6e1b9b113fbd1f1824292f54886 345 SUPERFAMILY SSF141868 101 334 6.28E-57 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_22220 b6d0c6e1b9b113fbd1f1824292f54886 345 Gene3D G3DSA:3.20.20.450 96 340 9.3E-57 T 15-10-2018 IPR035919 EAL domain superfamily C2I28_22220 b6d0c6e1b9b113fbd1f1824292f54886 345 Pfam PF00563 EAL domain 102 332 2.2E-49 T 15-10-2018 IPR001633 EAL domain C2I28_24955 ee47fc61f30b45342aa43298e1d88b43 395 Gene3D G3DSA:1.20.1250.20 4 198 2.1E-19 T 15-10-2018 C2I28_24955 ee47fc61f30b45342aa43298e1d88b43 395 Gene3D G3DSA:1.20.1250.20 199 390 6.2E-24 T 15-10-2018 C2I28_24955 ee47fc61f30b45342aa43298e1d88b43 395 SUPERFAMILY SSF103473 6 387 1.7E-51 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_24955 ee47fc61f30b45342aa43298e1d88b43 395 Pfam PF07690 Major Facilitator Superfamily 15 227 1.1E-14 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_20705 b7bef47287ba7a8b3b2cf2f65f3220a6 175 Pfam PF09349 OHCU decarboxylase 10 161 5.8E-41 T 15-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 C2I28_20705 b7bef47287ba7a8b3b2cf2f65f3220a6 175 SUPERFAMILY SSF158694 6 164 4.84E-47 T 15-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 C2I28_20705 b7bef47287ba7a8b3b2cf2f65f3220a6 175 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 13 163 4.4E-59 T 15-10-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 C2I28_20705 b7bef47287ba7a8b3b2cf2f65f3220a6 175 Gene3D G3DSA:1.10.3330.10 4 173 4.8E-58 T 15-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 C2I28_20250 723e52b558aec22b94c88390667a8615 141 Gene3D G3DSA:3.10.129.10 1 140 1.1E-55 T 15-10-2018 C2I28_20250 723e52b558aec22b94c88390667a8615 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 138 1.1E-51 T 15-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_20250 723e52b558aec22b94c88390667a8615 141 SUPERFAMILY SSF54637 1 138 1.68E-44 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_20250 723e52b558aec22b94c88390667a8615 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 31.131 T 15-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_20250 723e52b558aec22b94c88390667a8615 141 Pfam PF07977 FabA-like domain 11 133 5.9E-32 T 15-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 C2I28_23200 7e3143c2a267d5d1205ec6d1f25caa4f 445 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 2.4E-27 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_23200 7e3143c2a267d5d1205ec6d1f25caa4f 445 Pfam PF00209 Sodium:neurotransmitter symporter family 144 441 6.2E-36 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_23200 7e3143c2a267d5d1205ec6d1f25caa4f 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 6.4E-14 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_23200 7e3143c2a267d5d1205ec6d1f25caa4f 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 6.4E-14 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_23200 7e3143c2a267d5d1205ec6d1f25caa4f 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 6.4E-14 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_23200 7e3143c2a267d5d1205ec6d1f25caa4f 445 SUPERFAMILY SSF161070 5 442 4.84E-138 T 15-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I28_05020 092161646d9d9745cf43b5b40f8647f4 196 Pfam PF00694 Aconitase C-terminal domain 1 123 2.4E-36 T 15-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 C2I28_05020 092161646d9d9745cf43b5b40f8647f4 196 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 196 39.947 T 15-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 C2I28_05020 092161646d9d9745cf43b5b40f8647f4 196 SUPERFAMILY SSF52016 1 191 4.71E-59 T 15-10-2018 C2I28_05020 092161646d9d9745cf43b5b40f8647f4 196 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 2.2E-79 T 15-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 C2I28_05020 092161646d9d9745cf43b5b40f8647f4 196 Gene3D G3DSA:3.20.19.10 1 174 4.1E-72 T 15-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 C2I28_10830 a5835235296c87e85fc489d6474182a6 202 Pfam PF02632 BioY family 37 184 6.7E-32 T 15-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I28_10830 a5835235296c87e85fc489d6474182a6 202 Gene3D G3DSA:1.10.1760.20 1 193 6.7E-45 T 15-10-2018 C2I28_10830 a5835235296c87e85fc489d6474182a6 202 PIRSF PIRSF016661 1 193 5.2E-45 T 15-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 Gene3D G3DSA:1.10.579.10 291 475 1.5E-85 T 15-10-2018 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 SUPERFAMILY SSF52425 2 170 2.88E-52 T 15-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 Gene3D G3DSA:1.25.40.80 129 284 1.5E-81 T 15-10-2018 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 322 334 - T 15-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal C2I28_01915 4db9fee2470aa711caa2156427652c89 475 PRINTS PR00147 DNA photolyase signature 138 154 9.4E-23 T 15-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 PRINTS PR00147 DNA photolyase signature 322 338 9.4E-23 T 15-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 PRINTS PR00147 DNA photolyase signature 342 360 9.4E-23 T 15-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 PRINTS PR00147 DNA photolyase signature 381 395 9.4E-23 T 15-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 SUPERFAMILY SSF48173 188 473 7.46E-113 T 15-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 342 361 - T 15-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal C2I28_01915 4db9fee2470aa711caa2156427652c89 475 Pfam PF00875 DNA photolyase 6 156 1.1E-45 T 15-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 Pfam PF03441 FAD binding domain of DNA photolyase 273 472 1.6E-90 T 15-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 C2I28_01915 4db9fee2470aa711caa2156427652c89 475 Gene3D G3DSA:3.40.50.620 6 199 1.5E-81 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_02995 e2cc4d8632018834606c508fa87f34b8 541 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 12 538 1.5E-177 T 15-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I28_02995 e2cc4d8632018834606c508fa87f34b8 541 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 541 30.211 T 15-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I28_02995 e2cc4d8632018834606c508fa87f34b8 541 Pfam PF10079 Bacillithiol biosynthesis BshC 1 537 1.6E-165 T 15-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I28_02995 e2cc4d8632018834606c508fa87f34b8 541 PIRSF PIRSF012535 1 539 1.9E-189 T 15-10-2018 IPR011199 Bacillithiol biosynthesis BshC C2I28_03010 1b56d8bc32c3693e0f9788eaab5fa95d 513 Gene3D G3DSA:3.90.226.10 3 254 2.3E-74 T 15-10-2018 C2I28_03010 1b56d8bc32c3693e0f9788eaab5fa95d 513 Pfam PF01039 Carboxyl transferase domain 33 510 4.5E-155 T 15-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 C2I28_03010 1b56d8bc32c3693e0f9788eaab5fa95d 513 SUPERFAMILY SSF52096 240 511 2.99E-81 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_03010 1b56d8bc32c3693e0f9788eaab5fa95d 513 SUPERFAMILY SSF52096 11 252 3.56E-63 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_03010 1b56d8bc32c3693e0f9788eaab5fa95d 513 Gene3D G3DSA:3.90.226.10 256 513 9.3E-84 T 15-10-2018 C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 SMART SM00490 254 335 3.8E-36 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 502 44.8 T 15-10-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 SUPERFAMILY SSF52540 71 356 1.83E-76 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 SMART SM00487 21 218 2.4E-65 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 Gene3D G3DSA:3.40.50.300 1 207 2.9E-76 T 15-10-2018 C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 Gene3D G3DSA:3.40.50.300 210 436 1.1E-54 T 15-10-2018 C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 15-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 Pfam PF00271 Helicase conserved C-terminal domain 227 335 2.7E-31 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_09115 2d7c9aedbb0a9422cb740f1e377798ff 503 Pfam PF00270 DEAD/DEAH box helicase 26 190 1.6E-50 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 SMART SM01001 3 154 2.0E-105 T 15-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 Gene3D G3DSA:3.40.50.7700 1 162 7.2E-76 T 15-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.819 T 15-10-2018 IPR033747 Class I PurE C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 SUPERFAMILY SSF52255 4 160 4.19E-69 T 15-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 Pfam PF00731 AIR carboxylase 4 150 1.3E-67 T 15-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 161 1.4E-68 T 15-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I28_09425 f1c704ff72e156b7d549344c3bf83354 162 PIRSF PIRSF001338 1 162 3.9E-71 T 15-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 C2I28_21115 23d8b1cdd2b81f47ca9505054db59c7e 539 Gene3D G3DSA:3.30.750.24 408 525 7.1E-23 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_21115 23d8b1cdd2b81f47ca9505054db59c7e 539 Pfam PF00916 Sulfate permease family 15 379 6.3E-95 T 15-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I28_21115 23d8b1cdd2b81f47ca9505054db59c7e 539 Pfam PF01740 STAS domain 430 523 2.3E-16 T 15-10-2018 IPR002645 STAS domain C2I28_21115 23d8b1cdd2b81f47ca9505054db59c7e 539 SUPERFAMILY SSF52091 430 523 1.96E-17 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_04700 738208c75145cadaf9b853ba5a9b763e 153 SUPERFAMILY SSF69500 1 144 9.55E-58 T 15-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily C2I28_04700 738208c75145cadaf9b853ba5a9b763e 153 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 9.6E-57 T 15-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 C2I28_04700 738208c75145cadaf9b853ba5a9b763e 153 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 1.9E-60 T 15-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 C2I28_04700 738208c75145cadaf9b853ba5a9b763e 153 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.446 T 15-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 C2I28_04700 738208c75145cadaf9b853ba5a9b763e 153 Gene3D G3DSA:3.50.80.10 1 148 2.4E-59 T 15-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily C2I28_08125 69adf01fce75cb83c96170efaad264ab 149 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 45.66 T 15-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 C2I28_08125 69adf01fce75cb83c96170efaad264ab 149 SUPERFAMILY SSF53927 1 146 3.72E-52 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_08125 69adf01fce75cb83c96170efaad264ab 149 Pfam PF14437 MafB19-like deaminase 1 142 4.6E-43 T 15-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 C2I28_08125 69adf01fce75cb83c96170efaad264ab 149 Gene3D G3DSA:3.40.140.10 1 149 3.9E-59 T 15-10-2018 C2I28_08125 69adf01fce75cb83c96170efaad264ab 149 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 46 83 - T 15-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I28_17650 f57f184d8c9a90b13a830dd09d0dd0db 226 SUPERFAMILY SSF53335 9 199 2.76E-36 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_17650 f57f184d8c9a90b13a830dd09d0dd0db 226 Gene3D G3DSA:3.40.50.150 26 226 3.9E-56 T 15-10-2018 C2I28_17650 f57f184d8c9a90b13a830dd09d0dd0db 226 Pfam PF08241 Methyltransferase domain 53 144 4.9E-23 T 15-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I28_22865 630b098103455fa52e069374837b32df 211 Gene3D G3DSA:3.20.20.70 1 207 1.2E-65 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_22865 630b098103455fa52e069374837b32df 211 SUPERFAMILY SSF51366 7 206 1.65E-29 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_22865 630b098103455fa52e069374837b32df 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 198 1.9E-20 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_22865 630b098103455fa52e069374837b32df 211 SMART SM00934 2 201 3.2E-31 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_23885 c66264ec47daa456dbb6565522d3f289 294 Gene3D G3DSA:3.30.70.120 203 278 5.0E-24 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_23885 c66264ec47daa456dbb6565522d3f289 294 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 225 9.4E-65 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_23885 c66264ec47daa456dbb6565522d3f289 294 PIRSF PIRSF006483 3 293 4.4E-96 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_23885 c66264ec47daa456dbb6565522d3f289 294 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 1.2E-22 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_21235 3085862c3def6e26336585330967127f 451 Pfam PF05525 Branched-chain amino acid transport protein 10 431 1.8E-165 T 15-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I28_21235 3085862c3def6e26336585330967127f 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 421 3.9E-159 T 15-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I28_10895 bc1c4f1d28dedd94e7e7bb3bfc28d202 207 SUPERFAMILY SSF51391 4 196 6.8E-46 T 15-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_10895 bc1c4f1d28dedd94e7e7bb3bfc28d202 207 Gene3D G3DSA:3.20.20.70 5 199 1.5E-54 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_10895 bc1c4f1d28dedd94e7e7bb3bfc28d202 207 Pfam PF02581 Thiamine monophosphate synthase 9 179 2.4E-41 T 15-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_23855 ae3cf8e73752c815ceb5eb1bde7b4c09 210 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 179 7.9E-40 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_16070 e53755081091c17076e26171f4ff45b3 149 Pfam PF13673 Acetyltransferase (GNAT) domain 45 134 3.1E-14 T 15-10-2018 IPR000182 GNAT domain C2I28_16070 e53755081091c17076e26171f4ff45b3 149 SUPERFAMILY SSF55729 8 134 1.1E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_16070 e53755081091c17076e26171f4ff45b3 149 Gene3D G3DSA:3.40.630.30 5 143 1.6E-21 T 15-10-2018 C2I28_03255 2c53d812fb97870e34aec583764ce806 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 5.0E-14 T 15-10-2018 IPR020076 Protein of unknown function DUF2768 C2I28_03255 2c53d812fb97870e34aec583764ce806 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 3.7E-25 T 15-10-2018 IPR020076 Protein of unknown function DUF2768 C2I28_12005 949da0103033c494a94374cb29b92cb6 209 SUPERFAMILY SSF110395 4 204 4.05E-65 T 15-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_12005 949da0103033c494a94374cb29b92cb6 209 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 3 205 28.636 T 15-10-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_12005 949da0103033c494a94374cb29b92cb6 209 Gene3D G3DSA:3.20.20.380 3 206 1.0E-79 T 15-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_12005 949da0103033c494a94374cb29b92cb6 209 Pfam PF03932 CutC family 4 203 3.0E-72 T 15-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 C2I28_12840 88e19ac447bac9ecfc889576dabf5824 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 274 8.9E-18 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_12840 88e19ac447bac9ecfc889576dabf5824 284 SUPERFAMILY SSF161098 48 275 5.89E-66 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_12840 88e19ac447bac9ecfc889576dabf5824 284 Gene3D G3DSA:1.10.3720.10 44 282 2.2E-75 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_12840 88e19ac447bac9ecfc889576dabf5824 284 SUPERFAMILY SSF160964 3 35 4.18E-5 T 15-10-2018 C2I28_23510 b732fea08f0c7bea85481b3139f875de 104 SMART SM00418 5 102 1.4E-10 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_23510 b732fea08f0c7bea85481b3139f875de 104 SUPERFAMILY SSF46785 4 101 2.69E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23510 b732fea08f0c7bea85481b3139f875de 104 Gene3D G3DSA:1.10.10.10 1 104 8.8E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23510 b732fea08f0c7bea85481b3139f875de 104 Pfam PF12840 Helix-turn-helix domain 5 82 2.2E-12 T 15-10-2018 C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.2E-10 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 SUPERFAMILY SSF51735 114 252 2.46E-39 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 Gene3D G3DSA:3.90.180.10 14 321 1.4E-87 T 15-10-2018 C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 Gene3D G3DSA:3.40.50.720 122 293 1.4E-87 T 15-10-2018 C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 Pfam PF00107 Zinc-binding dehydrogenase 153 265 1.9E-23 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 SUPERFAMILY SSF50129 10 141 3.8E-38 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_13010 753664e1be97e8f93ab5d000bd3df5f6 326 SMART SM00829 13 323 6.1E-31 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_19905 2d5a0b9fbd5e2939c9bcee4006189e68 218 SMART SM00882 4 215 2.8E-70 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_19905 2d5a0b9fbd5e2939c9bcee4006189e68 218 SUPERFAMILY SSF100950 2 215 3.05E-78 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_19905 2d5a0b9fbd5e2939c9bcee4006189e68 218 Pfam PF01144 Coenzyme A transferase 8 214 6.8E-64 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_19905 2d5a0b9fbd5e2939c9bcee4006189e68 218 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 2 214 9.7E-75 T 15-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 C2I28_19905 2d5a0b9fbd5e2939c9bcee4006189e68 218 Gene3D G3DSA:3.40.1080.10 1 218 1.5E-81 T 15-10-2018 C2I28_19905 2d5a0b9fbd5e2939c9bcee4006189e68 218 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 16 31 - T 15-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 C2I28_26010 d1e22fb60a8b28d03a04c0a66039170d 253 SMART SM00382 30 219 7.1E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_26010 d1e22fb60a8b28d03a04c0a66039170d 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_26010 d1e22fb60a8b28d03a04c0a66039170d 253 SUPERFAMILY SSF52540 5 223 8.21E-59 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_26010 d1e22fb60a8b28d03a04c0a66039170d 253 Gene3D G3DSA:3.40.50.300 1 236 2.1E-64 T 15-10-2018 C2I28_26010 d1e22fb60a8b28d03a04c0a66039170d 253 Pfam PF00005 ABC transporter 21 162 2.4E-28 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_05255 e1366351dac7cc3f6cf6ae421549bb41 86 Pfam PF05164 Cell division protein ZapA 10 80 6.7E-16 T 15-10-2018 IPR007838 Cell division protein ZapA-like C2I28_05255 e1366351dac7cc3f6cf6ae421549bb41 86 SUPERFAMILY SSF102829 10 81 4.18E-19 T 15-10-2018 IPR036192 Cell division protein ZapA-like superfamily C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 SUPERFAMILY SSF55681 11 293 2.4E-96 T 15-10-2018 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 Gene3D G3DSA:3.40.50.800 299 404 9.7E-30 T 15-10-2018 IPR036621 Anticodon-binding domain superfamily C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 91 296 3.6E-38 T 15-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 3 398 3.4E-169 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 Gene3D G3DSA:3.30.930.10 1 298 2.2E-130 T 15-10-2018 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 PRINTS PR01047 Threonyl-tRNA synthetase signature 130 153 2.0E-53 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 PRINTS PR01047 Threonyl-tRNA synthetase signature 97 125 2.0E-53 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 PRINTS PR01047 Threonyl-tRNA synthetase signature 274 287 2.0E-53 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 PRINTS PR01047 Threonyl-tRNA synthetase signature 231 259 2.0E-53 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 PRINTS PR01047 Threonyl-tRNA synthetase signature 301 313 2.0E-53 T 15-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 SUPERFAMILY SSF52954 297 400 3.02E-27 T 15-10-2018 C2I28_20035 5bfa483e5e1462acf07fe395f82773f4 405 Pfam PF03129 Anticodon binding domain 311 392 7.1E-20 T 15-10-2018 IPR004154 Anticodon-binding C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 SUPERFAMILY SSF46689 420 472 1.11E-6 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 Gene3D G3DSA:1.10.8.60 339 418 4.0E-22 T 15-10-2018 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 SMART SM00091 23 90 0.0017 T 15-10-2018 IPR000014 PAS domain C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 379 388 - T 15-10-2018 IPR025944 Sigma-54 interaction domain, conserved site C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 SUPERFAMILY SSF52540 164 408 4.97E-66 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 Pfam PF00989 PAS fold 24 127 1.4E-8 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 SMART SM00382 185 330 1.5E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 SUPERFAMILY SSF55785 13 123 8.72E-13 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 253 268 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 Pfam PF00158 Sigma-54 interaction domain 166 333 1.9E-68 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 Gene3D G3DSA:3.40.50.300 150 338 1.8E-64 T 15-10-2018 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 189 202 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 25 138 2.3E-11 T 15-10-2018 IPR000014 PAS domain C2I28_17215 d769ad8ae55b6da7c449b5ad8ec9fe9a 476 Gene3D G3DSA:3.30.450.20 10 128 1.8E-16 T 15-10-2018 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 SUPERFAMILY SSF53187 5 371 4.28E-62 T 15-10-2018 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 PIRSF PIRSF001123 263 372 0.0087 T 15-10-2018 IPR008007 Peptidase M42 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 PIRSF PIRSF001123 4 98 0.052 T 15-10-2018 IPR008007 Peptidase M42 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 PIRSF PIRSF001123 80 184 1.4E-4 T 15-10-2018 IPR008007 Peptidase M42 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 Pfam PF07687 Peptidase dimerisation domain 181 274 2.5E-15 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 Gene3D G3DSA:3.40.630.10 14 363 3.4E-133 T 15-10-2018 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 367 9.1E-165 T 15-10-2018 IPR010162 Peptidase M20B, peptidase T-like C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 Pfam PF01546 Peptidase family M20/M25/M40 74 368 8.7E-22 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 15-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 SUPERFAMILY SSF55031 180 285 7.72E-22 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 Gene3D G3DSA:3.30.70.360 177 288 3.4E-133 T 15-10-2018 C2I28_03690 247e2a8de908e813d7baf46a51b12f30 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 15-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 Gene3D G3DSA:3.40.190.80 147 266 1.4E-34 T 15-10-2018 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 Gene3D G3DSA:3.30.540.10 1 144 9.4E-46 T 15-10-2018 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 SUPERFAMILY SSF56655 5 259 1.44E-74 T 15-10-2018 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 Pfam PF00459 Inositol monophosphatase family 8 259 1.4E-67 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 1.1E-39 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.1E-39 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 1.1E-39 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 1.1E-39 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.1E-39 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 1.1E-39 T 15-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 15-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 C2I28_14830 6503d9416cc72f85b8b4d29f782c5282 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 15-10-2018 IPR020583 Inositol monophosphatase, metal-binding site C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 7.7E-4 T 15-10-2018 C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.5E-46 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.5E-46 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.5E-46 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.5E-46 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.5E-46 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.5E-46 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 Gene3D G3DSA:3.40.50.720 1 253 1.5E-85 T 15-10-2018 C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 SUPERFAMILY SSF51735 7 250 3.64E-84 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 2.7E-69 T 15-10-2018 C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.0E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.0E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17265 fdac980baae21f96dd3b4639ac77314e 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.0E-15 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 Gene3D G3DSA:3.40.50.2300 61 308 5.4E-65 T 15-10-2018 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.7E-18 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 Pfam PF13377 Periplasmic binding protein-like domain 169 331 1.1E-37 T 15-10-2018 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 SUPERFAMILY SSF47413 3 60 3.74E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.1E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.1E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 Gene3D G3DSA:3.40.50.2300 160 289 5.4E-65 T 15-10-2018 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 SMART SM00354 2 72 3.1E-27 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 SUPERFAMILY SSF53822 62 333 9.26E-70 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 15-10-2018 C2I28_17440 7a6f761b0c2def96f381aea262c181c7 337 Gene3D G3DSA:1.10.260.40 2 60 1.1E-20 T 15-10-2018 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.0E-19 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 Gene3D G3DSA:3.40.50.2300 61 301 6.2E-66 T 15-10-2018 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 SUPERFAMILY SSF53822 60 323 8.05E-66 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 15-10-2018 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.3E-7 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.3E-7 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 Pfam PF13377 Periplasmic binding protein-like domain 164 322 1.5E-28 T 15-10-2018 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 Gene3D G3DSA:3.40.50.2300 154 283 6.2E-66 T 15-10-2018 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 SMART SM00354 1 71 2.4E-35 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 SUPERFAMILY SSF47413 2 59 3.84E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_12795 e1a6c250c976dd9917e8c8e5ffeab738 329 Gene3D G3DSA:1.10.260.40 3 59 2.3E-24 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 SUPERFAMILY SSF103473 7 428 5.62E-69 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 Gene3D G3DSA:1.20.1720.10 8 245 2.3E-49 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 Pfam PF07690 Major Facilitator Superfamily 13 194 1.4E-36 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 Pfam PF07690 Major Facilitator Superfamily 263 427 7.5E-21 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 Gene3D G3DSA:1.20.1250.20 247 433 1.3E-26 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.2E-8 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 394 413 1.2E-8 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 293 317 1.2E-8 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 1.2E-8 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.2E-8 T 15-10-2018 C2I28_16170 1a314d0c255112f274ea2e218b6e04f8 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.2E-8 T 15-10-2018 C2I28_15110 da54a6b67714fae332390bce6bf343c1 381 PIRSF PIRSF001434 1 380 2.1E-140 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_15110 da54a6b67714fae332390bce6bf343c1 381 Gene3D G3DSA:3.40.640.10 1 245 5.4E-91 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_15110 da54a6b67714fae332390bce6bf343c1 381 Gene3D G3DSA:3.90.1150.10 246 381 4.8E-50 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_15110 da54a6b67714fae332390bce6bf343c1 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 1.5E-151 T 15-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 C2I28_15110 da54a6b67714fae332390bce6bf343c1 381 SUPERFAMILY SSF53383 9 377 8.87E-115 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 418 1.7E-140 T 15-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 Gene3D G3DSA:1.10.240.10 223 325 3.9E-40 T 15-10-2018 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 SUPERFAMILY SSF52374 1 323 1.08E-106 T 15-10-2018 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 Gene3D G3DSA:3.10.290.10 326 419 3.9E-35 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 5.2E-89 T 15-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 Gene3D G3DSA:3.40.50.620 1 222 1.5E-89 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 SUPERFAMILY SSF55174 321 417 2.36E-24 T 15-10-2018 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 SMART SM00363 353 414 2.8E-8 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 1.1E-32 T 15-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 1.1E-32 T 15-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 1.1E-32 T 15-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 1.1E-32 T 15-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 46.253 T 15-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 C2I28_05605 2136d538a35a59d73a1b1fe29ebb6654 419 Pfam PF01479 S4 domain 354 399 1.8E-8 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08405 520bd35a420b6cc5ec5a193760627224 101 PIRSF PIRSF011576 1 101 3.7E-52 T 15-10-2018 IPR012504 Sporulation protein YabP C2I28_08405 520bd35a420b6cc5ec5a193760627224 101 Pfam PF07873 YabP family 18 83 1.3E-19 T 15-10-2018 IPR022476 Sporulation protein YabP/YqfC C2I28_08405 520bd35a420b6cc5ec5a193760627224 101 Gene3D G3DSA:2.60.40.2000 26 83 3.5E-23 T 15-10-2018 IPR038705 YabP superfamily C2I28_08405 520bd35a420b6cc5ec5a193760627224 101 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 18 101 4.9E-34 T 15-10-2018 IPR012504 Sporulation protein YabP C2I28_08405 520bd35a420b6cc5ec5a193760627224 101 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 18 101 4.0E-36 T 15-10-2018 IPR012504 Sporulation protein YabP C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 6.1E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 6.1E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 3.5E-20 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 Gene3D G3DSA:1.10.10.10 9 76 2.4E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 SUPERFAMILY SSF46785 8 80 1.23E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 SMART SM00345 17 76 1.2E-19 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 Gene3D G3DSA:3.40.1410.10 83 244 1.8E-40 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 SUPERFAMILY SSF64288 64 243 2.04E-40 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 SMART SM00866 98 237 1.7E-28 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_26035 56bb4481e8ee39cac09b9d6eb1978cde 244 Pfam PF07702 UTRA domain 99 237 1.7E-29 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 Gene3D G3DSA:1.10.3730.40 182 341 2.3E-70 T 15-10-2018 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 SUPERFAMILY SSF51735 3 182 3.19E-74 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 45.341 T 15-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 PIRSF PIRSF000116 1 206 4.0E-43 T 15-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 PIRSF PIRSF000116 202 333 5.7E-15 T 15-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 SUPERFAMILY SSF48179 183 331 2.04E-71 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 3.6E-77 T 15-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 5.4E-147 T 15-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 5.1E-67 T 15-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 C2I28_05040 bb84ac896df179618a8d22e13c7e1823 341 Gene3D G3DSA:3.40.50.720 1 181 2.4E-81 T 15-10-2018 C2I28_03280 32af202069a281006846ece2aa77970c 404 Gene3D G3DSA:1.20.1250.20 204 396 3.9E-34 T 15-10-2018 C2I28_03280 32af202069a281006846ece2aa77970c 404 Gene3D G3DSA:1.20.1250.20 5 200 4.6E-43 T 15-10-2018 C2I28_03280 32af202069a281006846ece2aa77970c 404 SUPERFAMILY SSF103473 6 395 7.85E-80 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_03280 32af202069a281006846ece2aa77970c 404 Pfam PF07690 Major Facilitator Superfamily 14 355 1.7E-61 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 15-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 Gene3D G3DSA:3.40.50.1170 1 207 1.5E-66 T 15-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 Pfam PF00710 Asparaginase, N-terminal 4 191 2.0E-58 T 15-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 SMART SM00870 3 318 6.0E-133 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 81 91 - T 15-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 PIRSF PIRSF500176 1 323 5.9E-92 T 15-10-2018 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 1.3E-14 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.3E-14 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 1.3E-14 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 Gene3D G3DSA:3.40.50.40 208 323 2.1E-28 T 15-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 PIRSF PIRSF001220 1 323 2.3E-92 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_03325 e9937c386f190895a54bb9340147f0d6 323 SUPERFAMILY SSF53774 1 322 3.93E-99 T 15-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SUPERFAMILY SSF50249 635 719 2.76E-22 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SUPERFAMILY SSF53098 319 466 6.83E-50 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SUPERFAMILY SSF47781 467 553 1.33E-27 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Gene3D G3DSA:1.10.3500.10 118 494 5.9E-156 T 15-10-2018 IPR023323 Tex-like domain superfamily C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Gene3D G3DSA:1.10.10.650 3 115 3.4E-39 T 15-10-2018 IPR023319 Tex-like protein, HTH domain superfamily C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Pfam PF12836 Helix-hairpin-helix motif 488 552 1.8E-28 T 15-10-2018 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SMART SM00732 323 421 1.8E-35 T 15-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SUPERFAMILY SSF158832 8 318 8.89E-116 T 15-10-2018 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SMART SM00316 649 720 1.9E-21 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Pfam PF16921 Tex protein YqgF-like domain 323 448 4.4E-57 T 15-10-2018 IPR032639 Tex protein, YqgF-like domain C2I28_09195 ec868055c129e0948fc5fca306039c85 724 SUPERFAMILY SSF47781 557 632 2.45E-15 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Gene3D G3DSA:1.10.150.310 496 630 9.4E-49 T 15-10-2018 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Gene3D G3DSA:2.40.50.140 635 721 1.5E-22 T 15-10-2018 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Pfam PF00575 S1 RNA binding domain 649 719 2.7E-16 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Gene3D G3DSA:3.30.420.140 322 448 5.9E-156 T 15-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 C2I28_09195 ec868055c129e0948fc5fca306039c85 724 Pfam PF09371 Tex-like protein N-terminal domain 15 198 1.3E-70 T 15-10-2018 IPR018974 Tex-like protein, N-terminal C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Pfam PF03123 CAT RNA binding domain 7 61 3.8E-22 T 15-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Gene3D G3DSA:1.10.1790.10 71 169 3.2E-33 T 15-10-2018 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 SUPERFAMILY SSF63520 180 276 1.44E-23 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Gene3D G3DSA:1.20.58.1950 226 277 1.9E-23 T 15-10-2018 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 SUPERFAMILY SSF50151 5 57 1.96E-15 T 15-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Gene3D G3DSA:1.20.890.100 170 224 3.0E-19 T 15-10-2018 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 ProSitePatterns PS00654 PRD domain signature. 102 114 - T 15-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Pfam PF00874 PRD domain 185 275 1.7E-19 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Pfam PF00874 PRD domain 80 167 3.0E-26 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 Gene3D G3DSA:2.30.24.10 1 70 6.1E-26 T 15-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 SUPERFAMILY SSF63520 58 171 1.96E-32 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_14545 b6213f501c070a40df2ec1dcf0b94c73 282 SMART SM01061 5 63 1.2E-23 T 15-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 C2I28_01890 a701dc22e8898a412809041f2d1a1eb2 584 Pfam PF06276 Ferric iron reductase FhuF-like transporter 401 559 5.2E-35 T 15-10-2018 IPR022770 Ferric iron reductase FhuF domain C2I28_01890 a701dc22e8898a412809041f2d1a1eb2 584 Gene3D G3DSA:1.10.510.40 359 554 1.5E-13 T 15-10-2018 C2I28_01890 a701dc22e8898a412809041f2d1a1eb2 584 Pfam PF04183 IucA / IucC family 136 370 1.3E-60 T 15-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 Pfam PF00072 Response regulator receiver domain 8 115 4.3E-32 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 SUPERFAMILY SSF52172 3 125 5.27E-43 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 SMART SM00448 5 115 1.9E-46 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 Gene3D G3DSA:1.10.10.10 136 238 8.4E-36 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 2.0E-27 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 SUPERFAMILY SSF46894 135 235 1.21E-31 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 SMART SM00862 156 233 8.5E-27 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_03405 a47b1513704728cfddccbc8cc5da51b9 238 Gene3D G3DSA:3.40.50.2300 1 132 8.9E-41 T 15-10-2018 C2I28_23905 b7cebcb251459b10adbeb520a711aeb7 235 Pfam PF13462 Thioredoxin 57 228 3.1E-36 T 15-10-2018 IPR012336 Thioredoxin-like fold C2I28_23905 b7cebcb251459b10adbeb520a711aeb7 235 SUPERFAMILY SSF52833 52 228 3.07E-35 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_23905 b7cebcb251459b10adbeb520a711aeb7 235 Gene3D G3DSA:3.40.30.10 42 235 2.6E-49 T 15-10-2018 C2I28_00275 3d577586a5bd4b809b6e58704e5507c3 248 SUPERFAMILY SSF53474 4 243 6.16E-39 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_00275 3d577586a5bd4b809b6e58704e5507c3 248 Pfam PF00561 alpha/beta hydrolase fold 5 230 3.8E-16 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00275 3d577586a5bd4b809b6e58704e5507c3 248 Gene3D G3DSA:3.40.50.1820 2 246 2.1E-43 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_00275 3d577586a5bd4b809b6e58704e5507c3 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 186 200 4.8E-5 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00275 3d577586a5bd4b809b6e58704e5507c3 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 77 90 4.8E-5 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_00275 3d577586a5bd4b809b6e58704e5507c3 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 76 4.8E-5 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_23065 907a2fe197899d14633e43a5c25ec042 233 Pfam PF05908 Poly-gamma-glutamate hydrolase 35 223 1.2E-67 T 15-10-2018 IPR008585 Poly-gamma-glutamate hydrolase C2I28_23065 907a2fe197899d14633e43a5c25ec042 233 Gene3D G3DSA:3.40.630.100 29 233 1.1E-62 T 15-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily C2I28_23530 8d1b07998a7b50a1701598a76cee051a 540 PIRSF PIRSF006060 443 534 11.0 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_23530 8d1b07998a7b50a1701598a76cee051a 540 PIRSF PIRSF006060 1 458 1.3E-75 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_23530 8d1b07998a7b50a1701598a76cee051a 540 Pfam PF13520 Amino acid permease 9 426 9.8E-48 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_23530 8d1b07998a7b50a1701598a76cee051a 540 Gene3D G3DSA:1.20.1740.10 1 459 5.1E-78 T 15-10-2018 C2I28_14705 e53cb95d8c63607f94bcc3c0a2618a70 287 Gene3D G3DSA:2.30.30.60 126 175 1.1E-20 T 15-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I28_14705 e53cb95d8c63607f94bcc3c0a2618a70 287 SUPERFAMILY SSF50182 111 169 1.86E-13 T 15-10-2018 IPR010920 LSM domain superfamily C2I28_14705 e53cb95d8c63607f94bcc3c0a2618a70 287 Gene3D G3DSA:3.30.70.100 176 263 2.4E-30 T 15-10-2018 C2I28_14705 e53cb95d8c63607f94bcc3c0a2618a70 287 SUPERFAMILY SSF82689 174 271 1.44E-23 T 15-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 C2I28_14705 e53cb95d8c63607f94bcc3c0a2618a70 287 SUPERFAMILY SSF82861 27 109 5.1E-14 T 15-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 C2I28_14705 e53cb95d8c63607f94bcc3c0a2618a70 287 Pfam PF00924 Mechanosensitive ion channel 68 265 6.5E-48 T 15-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I28_23105 c2b9f8d391d57a53abb40ff60feca9d8 139 Gene3D G3DSA:3.10.580.10 1 139 5.6E-43 T 15-10-2018 C2I28_23105 c2b9f8d391d57a53abb40ff60feca9d8 139 SUPERFAMILY SSF54631 1 130 3.03E-29 T 15-10-2018 C2I28_23105 c2b9f8d391d57a53abb40ff60feca9d8 139 Pfam PF00571 CBS domain 96 129 9.3E-4 T 15-10-2018 IPR000644 CBS domain C2I28_23105 c2b9f8d391d57a53abb40ff60feca9d8 139 Pfam PF00571 CBS domain 9 59 1.2E-12 T 15-10-2018 IPR000644 CBS domain C2I28_23105 c2b9f8d391d57a53abb40ff60feca9d8 139 SMART SM00116 12 60 3.2E-6 T 15-10-2018 IPR000644 CBS domain C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00412 Epoxide hydrolase signature 266 288 1.1E-14 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00412 Epoxide hydrolase signature 111 124 1.1E-14 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.1E-14 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.1E-14 T 15-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 Gene3D G3DSA:3.40.50.1820 4 290 2.6E-93 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 SUPERFAMILY SSF53474 6 291 1.82E-72 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 Pfam PF00561 alpha/beta hydrolase fold 27 141 7.6E-20 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.6E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.6E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_25190 ca6484b27fe3e096fe81b5e6cb556a88 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.6E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_25420 185a3937556a5041c7d2f7e878386a98 160 Gene3D G3DSA:3.40.630.30 4 136 1.2E-38 T 15-10-2018 C2I28_25420 185a3937556a5041c7d2f7e878386a98 160 SUPERFAMILY SSF55729 25 132 1.83E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_25420 185a3937556a5041c7d2f7e878386a98 160 Pfam PF13673 Acetyltransferase (GNAT) domain 45 134 2.9E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.7E-21 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.7E-21 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.7E-21 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 15-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 SUPERFAMILY SSF47729 1 90 7.51E-35 T 15-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 Gene3D G3DSA:4.10.520.10 1 90 1.5E-40 T 15-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.1E-37 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_11015 46d0dd3b48d03411cc413546130cf390 90 SMART SM00411 1 90 4.3E-48 T 15-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 C2I28_23960 f30a832d78375f23308e323e567f89dc 108 Pfam PF00893 Small Multidrug Resistance protein 3 94 2.3E-27 T 15-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I28_23960 f30a832d78375f23308e323e567f89dc 108 SUPERFAMILY SSF103481 5 105 1.96E-20 T 15-10-2018 C2I28_23960 f30a832d78375f23308e323e567f89dc 108 Gene3D G3DSA:1.10.3730.20 1 108 3.9E-36 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 570 630 2.1E-30 T 15-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Gene3D G3DSA:3.40.50.670 411 643 1.1E-100 T 15-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 SUPERFAMILY SSF56719 399 634 6.28E-85 T 15-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Pfam PF01751 Toprim domain 424 524 7.1E-16 T 15-10-2018 IPR006171 TOPRIM domain C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Pfam PF00204 DNA gyrase B 223 393 2.9E-57 T 15-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 4 642 0.0 T 15-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 SMART SM00387 34 178 2.6E-26 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 639 48.347 T 15-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Gene3D G3DSA:3.30.565.10 6 221 5.3E-87 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 177 3.0E-22 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 SUPERFAMILY SSF54211 223 394 1.63E-53 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 SMART SM00433 38 634 0.0 T 15-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 SUPERFAMILY SSF55874 8 220 3.41E-69 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 491 507 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 509 526 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 73 86 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 115 129 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 529 541 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 38 53 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 269 282 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 573 589 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR00418 DNA topoisomerase II family signature 425 439 6.8E-70 T 15-10-2018 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 9 19 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 222 244 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 313 329 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 363 377 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 475 484 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 610 626 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 594 606 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 PRINTS PR01159 DNA gyrase subunit B signature 377 397 1.9E-60 T 15-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 15-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 C2I28_20845 f70d4218a8875d01fa014cc33d1bce2f 658 Gene3D G3DSA:3.30.230.10 222 403 2.1E-70 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_01455 fca823786a830daeb25ed79671e6b588 441 Gene3D G3DSA:2.60.40.10 340 439 3.4E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_01455 fca823786a830daeb25ed79671e6b588 441 Pfam PF00149 Calcineurin-like phosphoesterase 50 243 1.2E-12 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_01455 fca823786a830daeb25ed79671e6b588 441 SUPERFAMILY SSF49265 339 425 3.65E-6 T 15-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 C2I28_01455 fca823786a830daeb25ed79671e6b588 441 Gene3D G3DSA:3.60.21.10 27 322 5.2E-33 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_01455 fca823786a830daeb25ed79671e6b588 441 SUPERFAMILY SSF56300 44 303 4.61E-36 T 15-10-2018 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 PRINTS PR00116 Arginase signature 256 270 1.1E-42 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 PRINTS PR00116 Arginase signature 221 250 1.1E-42 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 PRINTS PR00116 Arginase signature 95 110 1.1E-42 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 PRINTS PR00116 Arginase signature 172 190 1.1E-42 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 PRINTS PR00116 Arginase signature 118 145 1.1E-42 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 Gene3D G3DSA:3.40.800.10 1 299 4.1E-121 T 15-10-2018 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 ProSitePatterns PS01053 Arginase family signature. 224 245 - T 15-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 TIGRFAM TIGR01229 rocF_arginase: arginase 5 298 2.3E-110 T 15-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 Pfam PF00491 Arginase family 3 294 2.4E-82 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 SUPERFAMILY SSF52768 4 295 2.34E-97 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_08960 5346e9591d87aac2f62ac0e161214e3a 299 PIRSF PIRSF036979 1 297 9.3E-40 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_09495 4a7bdb9af54580344303f21142958157 101 PIRSF PIRSF012508 1 100 2.5E-50 T 15-10-2018 IPR013368 TrpR homologue YerC/YecD C2I28_09495 4a7bdb9af54580344303f21142958157 101 Pfam PF01371 Trp repressor protein 10 94 3.6E-36 T 15-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 C2I28_09495 4a7bdb9af54580344303f21142958157 101 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 4.0E-51 T 15-10-2018 IPR013368 TrpR homologue YerC/YecD C2I28_09495 4a7bdb9af54580344303f21142958157 101 SUPERFAMILY SSF48295 3 95 8.89E-34 T 15-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 C2I28_09495 4a7bdb9af54580344303f21142958157 101 Gene3D G3DSA:1.10.1270.10 2 101 7.1E-41 T 15-10-2018 IPR038116 TrpR-like superfamily C2I28_07980 aa70e3408bb4a4f356727209f95f9645 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 209 1.0E-51 T 15-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I28_07980 aa70e3408bb4a4f356727209f95f9645 238 PIRSF PIRSF003078 1 220 1.3E-59 T 15-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I28_07980 aa70e3408bb4a4f356727209f95f9645 238 Pfam PF02527 rRNA small subunit methyltransferase G 21 203 4.1E-60 T 15-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I28_07980 aa70e3408bb4a4f356727209f95f9645 238 SUPERFAMILY SSF53335 1 237 2.47E-48 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_07980 aa70e3408bb4a4f356727209f95f9645 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.615 T 15-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 C2I28_07980 aa70e3408bb4a4f356727209f95f9645 238 Gene3D G3DSA:3.40.50.150 1 238 3.1E-86 T 15-10-2018 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 SMART SM00387 605 714 1.1E-28 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 SMART SM00388 495 564 1.7E-10 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 487 3.3E-18 T 15-10-2018 IPR000014 PAS domain C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 692 2.4E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 645 659 2.4E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 698 711 2.4E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 673 2.4E-15 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 SUPERFAMILY SSF55874 554 712 9.82E-40 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 607 713 1.1E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Pfam PF13426 PAS domain 377 479 8.0E-13 T 15-10-2018 IPR000014 PAS domain C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 SUPERFAMILY SSF55785 359 478 2.62E-18 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 561 1.8E-10 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Gene3D G3DSA:3.30.565.10 562 718 7.9E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Gene3D G3DSA:3.30.450.20 163 282 1.6E-13 T 15-10-2018 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Pfam PF02743 Cache domain 50 266 1.1E-17 T 15-10-2018 IPR033479 Double Cache domain 1 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 SMART SM00091 367 433 2.8E-6 T 15-10-2018 IPR000014 PAS domain C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Gene3D G3DSA:3.30.450.20 356 482 4.2E-22 T 15-10-2018 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 Gene3D G3DSA:1.10.287.130 483 561 1.5E-18 T 15-10-2018 C2I28_19260 ed612254480e399c5fa6ca0d813a94b8 719 SUPERFAMILY SSF47384 484 562 3.92E-11 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 252 262 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 Pfam PF00082 Subtilase family 44 288 3.0E-56 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 SUPERFAMILY SSF52743 25 295 1.05E-86 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 Gene3D G3DSA:3.40.50.200 7 316 3.6E-119 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 49 60 - T 15-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 PRINTS PR00723 Subtilisin serine protease family (S8) signature 44 63 5.8E-25 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 PRINTS PR00723 Subtilisin serine protease family (S8) signature 86 99 5.8E-25 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 PRINTS PR00723 Subtilisin serine protease family (S8) signature 251 267 5.8E-25 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_12290 9524d9e221f09bcce21c734d45d9b11a 328 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 90 100 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 4 198 1.9E-63 T 15-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 Gene3D G3DSA:3.40.50.1000 6 207 1.3E-68 T 15-10-2018 IPR023214 HAD superfamily C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 195 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 29 42 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 43 56 1.5E-32 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 193 1.1E-21 T 15-10-2018 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 46 187 6.0E-9 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 6 185 1.2E-26 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 Gene3D G3DSA:1.10.150.240 17 91 1.3E-68 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_13170 9aa4993ce499e11f40425f8b7d84f5e7 219 SUPERFAMILY SSF56784 2 218 5.07E-53 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 7.8E-122 T 15-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 Gene3D G3DSA:2.30.140.10 1 52 3.3E-25 T 15-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 Pfam PF17284 Spermidine synthase tetramerisation domain 3 55 3.5E-20 T 15-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 42.055 T 15-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 Gene3D G3DSA:3.40.50.150 53 274 4.3E-77 T 15-10-2018 C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 Pfam PF01564 Spermine/spermidine synthase domain 58 236 5.1E-70 T 15-10-2018 C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 SUPERFAMILY SSF53335 3 274 4.46E-87 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_07535 56b061c42ab7e43b9dd7a99a5581ee37 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 15-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_18535 9551b2fb4c3fd78a3808d8b1dd990498 229 SUPERFAMILY SSF48613 3 222 9.35E-67 T 15-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I28_18535 9551b2fb4c3fd78a3808d8b1dd990498 229 PIRSF PIRSF003170 1 219 6.0E-31 T 15-10-2018 IPR026285 TenA_E protein C2I28_18535 9551b2fb4c3fd78a3808d8b1dd990498 229 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 216 6.1E-59 T 15-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 C2I28_18535 9551b2fb4c3fd78a3808d8b1dd990498 229 Gene3D G3DSA:1.20.910.10 1 226 1.1E-68 T 15-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 C2I28_18535 9551b2fb4c3fd78a3808d8b1dd990498 229 Pfam PF03070 TENA/THI-4/PQQC family 9 216 2.4E-52 T 15-10-2018 IPR004305 Thiaminase-2/PQQC C2I28_07265 0710becd98d06689bacd041ef660a3a6 273 SUPERFAMILY SSF117143 93 233 9.55E-13 T 15-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like C2I28_07265 0710becd98d06689bacd041ef660a3a6 273 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 190 269 4.3E-16 T 15-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I28_07265 0710becd98d06689bacd041ef660a3a6 273 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 143 2.8E-26 T 15-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G C2I28_07265 0710becd98d06689bacd041ef660a3a6 273 Pfam PF00460 Flagella basal body rod protein 7 35 5.3E-8 T 15-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I28_00970 8397cd399a3ccd56a6e841cb21a38171 171 Gene3D G3DSA:3.90.226.10 1 134 1.0E-20 T 15-10-2018 C2I28_00970 8397cd399a3ccd56a6e841cb21a38171 171 SUPERFAMILY SSF52096 3 164 1.05E-21 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_00970 8397cd399a3ccd56a6e841cb21a38171 171 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 126 6.1E-12 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_24055 6eb4c5afc155a680f5de7bd861a96319 187 Gene3D G3DSA:3.40.50.360 1 182 2.1E-53 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24055 6eb4c5afc155a680f5de7bd861a96319 187 Pfam PF02525 Flavodoxin-like fold 2 176 3.1E-36 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_24055 6eb4c5afc155a680f5de7bd861a96319 187 SUPERFAMILY SSF52218 1 181 9.33E-38 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_12815 69fcba11e7914fac718031c56ba8f559 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 311 7.1E-54 T 15-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I28_19050 ae4de9205331de63b384b6150d8c9d59 145 SUPERFAMILY SSF50249 4 80 1.16E-23 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_19050 ae4de9205331de63b384b6150d8c9d59 145 SMART SM00316 4 73 2.6E-25 T 15-10-2018 IPR022967 RNA-binding domain, S1 C2I28_19050 ae4de9205331de63b384b6150d8c9d59 145 Gene3D G3DSA:2.40.50.140 1 83 2.9E-27 T 15-10-2018 C2I28_19050 ae4de9205331de63b384b6150d8c9d59 145 Pfam PF00575 S1 RNA binding domain 3 73 4.2E-19 T 15-10-2018 IPR003029 S1 domain GO:0003676 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 297 1.7E-139 T 15-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 275 1.6E-25 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 SUPERFAMILY SSF51735 1 152 2.55E-48 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 1.1E-32 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 1.1E-32 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 1.1E-32 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 24 1.1E-32 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 SUPERFAMILY SSF48179 165 297 3.8E-43 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 Gene3D G3DSA:3.40.50.720 1 165 2.9E-52 T 15-10-2018 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 SMART SM01350 167 298 7.3E-7 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 235 247 - T 15-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 Gene3D G3DSA:1.10.1040.10 166 297 6.7E-52 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_14720 421a969eda219bcdf30e9dfc16f3b6ac 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 152 3.2E-45 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_18395 edb64def663b1d1f1e41e6446bf31535 295 SUPERFAMILY SSF53448 2 267 9.39E-67 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18395 edb64def663b1d1f1e41e6446bf31535 295 Gene3D G3DSA:3.90.550.10 1 290 6.8E-90 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18395 edb64def663b1d1f1e41e6446bf31535 295 Pfam PF00483 Nucleotidyl transferase 5 264 4.3E-35 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_18395 edb64def663b1d1f1e41e6446bf31535 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 2.7E-121 T 15-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 SUPERFAMILY SSF55920 3 246 3.93E-70 T 15-10-2018 IPR036005 Creatinase/aminopeptidase-like C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 2.0E-89 T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 Gene3D G3DSA:3.90.230.10 1 248 1.2E-85 T 15-10-2018 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 Pfam PF00557 Metallopeptidase family M24 11 238 1.2E-47 T 15-10-2018 IPR000994 Peptidase M24 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 Hamap MF_01974 Methionine aminopeptidase [map]. 1 248 35.546 T 15-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 189 201 1.1E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 1.1E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 157 169 1.1E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_15975 1196dcf2449ec8f7bbeca2bb11df20b6 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 88 104 1.1E-20 T 15-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 C2I28_06295 7e2aca9ff5e6e56017eae91c275cab38 386 Gene3D G3DSA:3.90.1150.10 29 377 7.2E-132 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_06295 7e2aca9ff5e6e56017eae91c275cab38 386 Gene3D G3DSA:3.40.640.10 60 281 7.2E-132 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_06295 7e2aca9ff5e6e56017eae91c275cab38 386 Pfam PF00155 Aminotransferase class I and II 29 378 1.1E-71 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_06295 7e2aca9ff5e6e56017eae91c275cab38 386 SUPERFAMILY SSF53383 5 384 9.74E-119 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_06295 7e2aca9ff5e6e56017eae91c275cab38 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 15-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I28_19250 9e46f97a448a7dfa552b3c6f9a357c32 170 SUPERFAMILY SSF55729 2 166 1.62E-44 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_19250 9e46f97a448a7dfa552b3c6f9a357c32 170 Gene3D G3DSA:3.40.630.30 1 168 6.2E-52 T 15-10-2018 C2I28_19250 9e46f97a448a7dfa552b3c6f9a357c32 170 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 2.2E-29 T 15-10-2018 IPR000182 GNAT domain C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 15-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 SMART SM00841 129 184 1.1E-33 T 15-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.6E-28 T 15-10-2018 IPR013185 Translation elongation factor, KOW-like C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.5E-26 T 15-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 SUPERFAMILY SSF50249 65 129 9.42E-21 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.1E-80 T 15-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 SUPERFAMILY SSF50249 128 185 4.8E-19 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Gene3D G3DSA:2.30.30.30 1 62 4.1E-31 T 15-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.348 T 15-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 SUPERFAMILY SSF50104 1 62 6.62E-22 T 15-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 PIRSF PIRSF005901 1 185 1.7E-71 T 15-10-2018 IPR020599 Translation elongation factor P/YeiP C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 6.1E-22 T 15-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Gene3D G3DSA:2.40.50.140 64 127 3.3E-26 T 15-10-2018 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 Gene3D G3DSA:2.40.50.140 128 185 1.1E-26 T 15-10-2018 C2I28_03920 c30eb2b3ca67f03c3a903c91e8ea161c 185 SMART SM01185 67 121 3.5E-25 T 15-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 C2I28_23505 75d7a0fd0e13560cf1c4c2e304172a80 496 Gene3D G3DSA:1.20.1250.20 234 448 2.1E-12 T 15-10-2018 C2I28_23505 75d7a0fd0e13560cf1c4c2e304172a80 496 SUPERFAMILY SSF103473 9 444 7.59E-41 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_23505 75d7a0fd0e13560cf1c4c2e304172a80 496 Pfam PF13347 MFS/sugar transport protein 16 437 4.0E-75 T 15-10-2018 C2I28_23505 75d7a0fd0e13560cf1c4c2e304172a80 496 Gene3D G3DSA:1.20.1250.20 6 205 1.8E-16 T 15-10-2018 C2I28_20330 49b7f6aec52d11effca62a46936f1475 173 SUPERFAMILY SSF54518 38 139 1.96E-9 T 15-10-2018 IPR025659 Tubby-like, C-terminal C2I28_11070 69c4ba8474413040f4dc6ccefa1e500b 114 Pfam PF08963 Protein of unknown function (DUF1878) 1 109 8.1E-32 T 15-10-2018 IPR015058 Protein of unknown function DUF1878 C2I28_11070 69c4ba8474413040f4dc6ccefa1e500b 114 SUPERFAMILY SSF109915 3 111 2.22E-31 T 15-10-2018 IPR035945 YhaI-like superfamily C2I28_11070 69c4ba8474413040f4dc6ccefa1e500b 114 ProDom PD073069 YHAI 3D-STRUCTURE 10 95 1.0E-14 T 15-10-2018 IPR015058 Protein of unknown function DUF1878 C2I28_11070 69c4ba8474413040f4dc6ccefa1e500b 114 Gene3D G3DSA:1.10.3750.10 1 114 3.2E-38 T 15-10-2018 IPR035945 YhaI-like superfamily C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 Pfam PF00342 Phosphoglucose isomerase 76 426 1.5E-26 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 SUPERFAMILY SSF53697 5 447 2.23E-146 T 15-10-2018 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 15-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 Gene3D G3DSA:3.40.50.10490 58 226 3.0E-152 T 15-10-2018 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 Gene3D G3DSA:3.40.50.10490 1 57 1.6E-19 T 15-10-2018 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 Gene3D G3DSA:3.40.50.10490 227 417 3.0E-152 T 15-10-2018 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 15-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 3.7E-28 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 3.7E-28 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 3.7E-28 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 3.7E-28 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 3.7E-28 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 3.7E-28 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06235 f6075564b0ae2197cdcc466d72ca5374 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 26.537 T 15-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 Pfam PF00571 CBS domain 279 331 1.2E-6 T 15-10-2018 IPR000644 CBS domain C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 Pfam PF00571 CBS domain 338 390 1.2E-5 T 15-10-2018 IPR000644 CBS domain C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 Gene3D G3DSA:3.10.580.10 279 391 3.8E-20 T 15-10-2018 C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 Gene3D G3DSA:3.40.50.300 2 270 1.7E-73 T 15-10-2018 C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 SUPERFAMILY SSF54631 275 391 9.98E-23 T 15-10-2018 C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 SMART SM00116 283 331 0.0043 T 15-10-2018 IPR000644 CBS domain C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 SMART SM00116 343 390 0.0092 T 15-10-2018 IPR000644 CBS domain C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 38 391 5.7E-155 T 15-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 SMART SM00382 54 243 9.9E-21 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 SUPERFAMILY SSF52540 44 273 9.72E-78 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 Pfam PF00005 ABC transporter 46 193 5.4E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12485 f30eeeaa87acb7965166756df73b0632 401 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_02150 d68f8271fc5f38bdd9fe233ee08ace41 265 PIRSF PIRSF004789 1 264 2.5E-108 T 15-10-2018 IPR005235 Metallophosphoesterase, YmdB-like C2I28_02150 d68f8271fc5f38bdd9fe233ee08ace41 265 Pfam PF13277 YmdB-like protein 4 255 1.3E-113 T 15-10-2018 IPR005235 Metallophosphoesterase, YmdB-like C2I28_02150 d68f8271fc5f38bdd9fe233ee08ace41 265 SUPERFAMILY SSF56300 1 257 1.55E-90 T 15-10-2018 C2I28_02150 d68f8271fc5f38bdd9fe233ee08ace41 265 Gene3D G3DSA:3.60.21.10 1 265 2.5E-119 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_02150 d68f8271fc5f38bdd9fe233ee08ace41 265 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 265 2.0E-118 T 15-10-2018 IPR005235 Metallophosphoesterase, YmdB-like C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Pfam PF00082 Subtilase family 462 699 9.9E-49 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 505 515 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 656 666 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 PRINTS PR00723 Subtilisin serine protease family (S8) signature 655 671 7.5E-15 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 PRINTS PR00723 Subtilisin serine protease family (S8) signature 501 514 7.5E-15 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 PRINTS PR00723 Subtilisin serine protease family (S8) signature 461 480 7.5E-15 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 SUPERFAMILY SSF52743 454 735 6.41E-85 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Gene3D G3DSA:2.60.120.380 29 140 4.9E-6 T 15-10-2018 C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Gene3D G3DSA:2.60.40.10 898 973 1.1E-10 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Gene3D G3DSA:2.60.40.10 981 1056 9.2E-13 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Gene3D G3DSA:2.60.40.10 814 892 2.0E-7 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Gene3D G3DSA:2.60.40.10 739 808 3.7E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13925 9395a60b6bc5242f67acf70a2839b1f3 1062 Gene3D G3DSA:3.40.50.200 392 738 1.2E-86 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_05630 a2dfd4c8dc15851cacf87235465272dc 218 SUPERFAMILY SSF103088 95 212 7.85E-31 T 15-10-2018 IPR036737 OmpA-like domain superfamily C2I28_05630 a2dfd4c8dc15851cacf87235465272dc 218 Gene3D G3DSA:3.30.1330.60 57 217 1.1E-47 T 15-10-2018 IPR036737 OmpA-like domain superfamily C2I28_05630 a2dfd4c8dc15851cacf87235465272dc 218 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 5 52 3.2E-19 T 15-10-2018 IPR025713 Motility protein B, N-terminal domain C2I28_05630 a2dfd4c8dc15851cacf87235465272dc 218 Pfam PF00691 OmpA family 107 206 6.2E-19 T 15-10-2018 IPR006665 OmpA-like domain C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 Gene3D G3DSA:3.20.20.80 1 386 1.9E-117 T 15-10-2018 C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 Pfam PF08532 Beta-galactosidase trimerisation domain 393 599 2.3E-51 T 15-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 Pfam PF02449 Beta-galactosidase 6 379 1.7E-119 T 15-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 Gene3D G3DSA:3.40.50.880 390 603 1.1E-49 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 PIRSF PIRSF001084 1 642 6.0E-178 T 15-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 SUPERFAMILY SSF51445 3 381 2.14E-96 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_17460 c730ce178d4ab0f28dac77dd311b9851 649 SUPERFAMILY SSF52317 390 599 1.74E-44 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 PIRSF PIRSF005572 1 380 8.1E-122 T 15-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 Pfam PF00266 Aminotransferase class-V 4 366 9.3E-80 T 15-10-2018 IPR000192 Aminotransferase class V domain C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 SUPERFAMILY SSF53383 3 376 3.89E-101 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 Gene3D G3DSA:1.10.260.50 15 278 1.2E-138 T 15-10-2018 C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 Gene3D G3DSA:3.90.1150.10 4 369 1.2E-138 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 Gene3D G3DSA:3.40.640.10 61 235 1.2E-138 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_04640 fab9210fd4762b74a862b999a90726d8 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 15-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site C2I28_09835 4ed8aa6c4161081407abf394376f081d 1060 TIGRFAM TIGR03929 T7_esaA_Nterm: type VII secretion protein EsaA 12 201 1.4E-59 T 15-10-2018 IPR023838 Type VII secretion system EsaA GO:0016021 C2I28_09835 4ed8aa6c4161081407abf394376f081d 1060 SUPERFAMILY SSF75704 531 600 7.72E-5 T 15-10-2018 C2I28_11135 9b0eab731948ddf56702c0c7a892417c 221 Pfam PF01569 PAP2 superfamily 70 200 6.4E-14 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_11135 9b0eab731948ddf56702c0c7a892417c 221 SUPERFAMILY SSF48317 13 204 6.67E-28 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_11135 9b0eab731948ddf56702c0c7a892417c 221 Gene3D G3DSA:1.20.144.10 120 219 2.1E-21 T 15-10-2018 C2I28_11135 9b0eab731948ddf56702c0c7a892417c 221 Gene3D G3DSA:1.20.144.10 9 119 1.3E-5 T 15-10-2018 C2I28_11135 9b0eab731948ddf56702c0c7a892417c 221 SMART SM00014 90 199 5.4E-12 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_15435 56d36bca166642134661a1851df89d7f 175 Pfam PF13302 Acetyltransferase (GNAT) domain 2 141 8.4E-30 T 15-10-2018 IPR000182 GNAT domain C2I28_15435 56d36bca166642134661a1851df89d7f 175 SUPERFAMILY SSF55729 2 143 9.66E-39 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_15435 56d36bca166642134661a1851df89d7f 175 Gene3D G3DSA:3.40.630.30 1 170 2.8E-43 T 15-10-2018 C2I28_19120 57fddc49d5ba7ded43bae995504c5111 303 SUPERFAMILY SSF52540 3 230 7.64E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19120 57fddc49d5ba7ded43bae995504c5111 303 Gene3D G3DSA:3.40.50.300 1 231 2.6E-57 T 15-10-2018 C2I28_19120 57fddc49d5ba7ded43bae995504c5111 303 Pfam PF00005 ABC transporter 21 162 2.4E-29 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_19120 57fddc49d5ba7ded43bae995504c5111 303 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_19120 57fddc49d5ba7ded43bae995504c5111 303 SMART SM00382 30 211 2.9E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 Pfam PF00005 ABC transporter 25 183 1.1E-30 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 2.6E-27 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 Gene3D G3DSA:3.40.50.300 1 330 5.3E-106 T 15-10-2018 C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 SMART SM00382 33 241 1.6E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 SUPERFAMILY SSF52540 4 254 1.3E-73 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15400 d9f5a7f35d9ce1f1d2349e8a89e90206 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 8.8E-20 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_26875 c7145427bac1928edace922f9c551e85 323 SUPERFAMILY SSF46955 68 119 3.3E-5 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_26875 c7145427bac1928edace922f9c551e85 323 Pfam PF12728 Helix-turn-helix domain 9 62 9.7E-7 T 15-10-2018 C2I28_26875 c7145427bac1928edace922f9c551e85 323 Pfam PF12728 Helix-turn-helix domain 68 119 1.3E-8 T 15-10-2018 C2I28_26875 c7145427bac1928edace922f9c551e85 323 Gene3D G3DSA:1.10.1660.10 65 129 1.4E-8 T 15-10-2018 C2I28_18340 e0692d5892f1c58e9f7981610e6efb4a 176 Pfam PF13302 Acetyltransferase (GNAT) domain 22 150 1.0E-9 T 15-10-2018 IPR000182 GNAT domain C2I28_18340 e0692d5892f1c58e9f7981610e6efb4a 176 SUPERFAMILY SSF55729 20 154 4.66E-16 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18340 e0692d5892f1c58e9f7981610e6efb4a 176 Gene3D G3DSA:3.40.630.30 25 152 3.0E-19 T 15-10-2018 C2I28_00965 5c9caa0ce9f9bc78411282ed56511991 772 Gene3D G3DSA:3.40.50.300 202 364 1.5E-8 T 15-10-2018 C2I28_00965 5c9caa0ce9f9bc78411282ed56511991 772 Pfam PF13245 AAA domain 215 578 1.5E-10 T 15-10-2018 C2I28_00965 5c9caa0ce9f9bc78411282ed56511991 772 Pfam PF13538 UvrD-like helicase C-terminal domain 709 751 1.1E-8 T 15-10-2018 IPR027785 UvrD-like helicase C-terminal domain C2I28_00965 5c9caa0ce9f9bc78411282ed56511991 772 Gene3D G3DSA:3.40.50.300 500 600 1.1E-7 T 15-10-2018 C2I28_00965 5c9caa0ce9f9bc78411282ed56511991 772 SUPERFAMILY SSF52540 203 757 4.0E-57 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_00965 5c9caa0ce9f9bc78411282ed56511991 772 Gene3D G3DSA:3.40.50.300 603 771 6.1E-55 T 15-10-2018 C2I28_22995 e5792eb4b5addf1833752105835729cf 236 Gene3D G3DSA:3.20.20.370 18 236 1.4E-54 T 15-10-2018 C2I28_22995 e5792eb4b5addf1833752105835729cf 236 Pfam PF01522 Polysaccharide deacetylase 38 152 9.1E-28 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_22995 e5792eb4b5addf1833752105835729cf 236 SUPERFAMILY SSF88713 18 234 1.29E-52 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PIRSF PIRSF000722 1 396 3.0E-155 T 15-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 SUPERFAMILY SSF53067 1 194 1.49E-73 T 15-10-2018 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 15-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 1.8E-178 T 15-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 15-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 Gene3D G3DSA:3.30.420.40 2 194 1.6E-76 T 15-10-2018 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 Gene3D G3DSA:3.30.420.40 195 396 3.6E-83 T 15-10-2018 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 SUPERFAMILY SSF53067 157 393 8.07E-95 T 15-10-2018 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PRINTS PR00471 Acetate kinase family signature 172 185 2.8E-47 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PRINTS PR00471 Acetate kinase family signature 299 312 2.8E-47 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PRINTS PR00471 Acetate kinase family signature 4 15 2.8E-47 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PRINTS PR00471 Acetate kinase family signature 321 337 2.8E-47 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PRINTS PR00471 Acetate kinase family signature 375 387 2.8E-47 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 PRINTS PR00471 Acetate kinase family signature 202 223 2.8E-47 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 Hamap MF_00020 Acetate kinase [ackA]. 1 396 199.903 T 15-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_05515 91d7a2b6fd832c0d4f5fec3b948bd39e 396 Pfam PF00871 Acetokinase family 3 388 1.5E-173 T 15-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 C2I28_21860 dc8a62c4fc57575ef8bdaa830617f94b 159 Pfam PF15565 Immunity protein 30 14 114 2.0E-12 T 15-10-2018 IPR029084 Immunity protein 30 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 Gene3D G3DSA:3.20.20.70 4 236 1.3E-29 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 Pfam PF04055 Radical SAM superfamily 29 125 4.9E-11 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 4 243 2.6E-115 T 15-10-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 PIRSF PIRSF000370 3 243 3.2E-50 T 15-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 SUPERFAMILY SSF102114 25 174 2.62E-12 T 15-10-2018 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 Pfam PF13353 4Fe-4S single cluster domain 15 117 6.0E-10 T 15-10-2018 C2I28_14425 85bd889fa7a6533846954603ea2e77b4 243 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 240 36.821 T 15-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 C2I28_15620 c27dd928916b14d09b68c74a465a5016 44 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 1 43 1.8E-14 T 15-10-2018 IPR022248 TNF receptor family, RELT C2I28_23480 6a4adc7178c00d175d64a413d1661c2e 147 PRINTS PR00332 Histidine triad family signature 10 26 7.5E-5 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_23480 6a4adc7178c00d175d64a413d1661c2e 147 PRINTS PR00332 Histidine triad family signature 31 49 7.5E-5 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_23480 6a4adc7178c00d175d64a413d1661c2e 147 PRINTS PR00332 Histidine triad family signature 96 106 7.5E-5 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_23480 6a4adc7178c00d175d64a413d1661c2e 147 Pfam PF01230 HIT domain 18 110 2.3E-15 T 15-10-2018 IPR001310 Histidine triad (HIT) protein C2I28_23480 6a4adc7178c00d175d64a413d1661c2e 147 SUPERFAMILY SSF54197 8 140 3.25E-29 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_23480 6a4adc7178c00d175d64a413d1661c2e 147 Gene3D G3DSA:3.30.428.10 3 146 1.2E-29 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_15900 bfeaf6fd811445f4a247e845ef9ab2ca 483 Gene3D G3DSA:2.115.10.20 29 477 2.6E-187 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15900 bfeaf6fd811445f4a247e845ef9ab2ca 483 Pfam PF02435 Levansucrase/Invertase 38 479 6.3E-156 T 15-10-2018 IPR003469 Glycoside hydrolase, family 68 GO:0009758|GO:0050053 C2I28_15900 bfeaf6fd811445f4a247e845ef9ab2ca 483 SUPERFAMILY SSF75005 38 482 6.0E-101 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_24395 07887a3dda2b8a3a0e67abb0fac85810 95 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 14 28 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24395 07887a3dda2b8a3a0e67abb0fac85810 95 Pfam PF00741 Gas vesicle protein 13 51 1.8E-13 T 15-10-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 SUPERFAMILY SSF52540 84 356 6.99E-89 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 Gene3D G3DSA:1.10.1140.10 354 472 6.5E-56 T 15-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 SMART SM00382 150 335 5.0E-7 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 SUPERFAMILY SSF50615 1 81 1.91E-27 T 15-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 Gene3D G3DSA:2.40.10.170 1 82 1.9E-32 T 15-10-2018 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 1.8E-25 T 15-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 15-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 SUPERFAMILY SSF47917 354 469 6.54E-52 T 15-10-2018 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 Gene3D G3DSA:3.40.50.300 84 352 6.0E-115 T 15-10-2018 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 57.712 T 15-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 2.3E-257 T 15-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 C2I28_07315 2897407e4b1be4923aedb942e56b83c9 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 6.4E-68 T 15-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 SMART SM00346 3 92 1.2E-19 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 Gene3D G3DSA:3.30.450.40 74 251 2.8E-54 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 Pfam PF01614 Bacterial transcriptional regulator 121 242 8.2E-35 T 15-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 SUPERFAMILY SSF55781 68 247 9.16E-48 T 15-10-2018 C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 Gene3D G3DSA:1.10.10.10 1 73 5.2E-19 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 SUPERFAMILY SSF46785 3 76 5.01E-15 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26000 ab2dc7299e70b89e95f5df57fdadebd6 252 Pfam PF09339 IclR helix-turn-helix domain 5 55 1.1E-12 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 SMART SM00387 288 381 5.9E-12 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 378 2.2E-11 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 Pfam PF07730 Histidine kinase 180 248 1.9E-16 T 15-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 SUPERFAMILY SSF55874 260 378 1.96E-20 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 Gene3D G3DSA:3.30.565.10 246 381 2.7E-30 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 PIRSF PIRSF003169 1 382 8.4E-152 T 15-10-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 C2I28_07185 0fbe244fc654f118a9731fb085f01590 382 Pfam PF05384 Sensor protein DegS 12 170 7.1E-57 T 15-10-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 C2I28_07600 f960a7581b0d5675887f0a96bed80500 160 SUPERFAMILY SSF81995 7 77 7.59E-5 T 15-10-2018 C2I28_07600 f960a7581b0d5675887f0a96bed80500 160 PIRSF PIRSF038931 1 160 8.9E-56 T 15-10-2018 IPR014099 Spore coat protein GerQ C2I28_07600 f960a7581b0d5675887f0a96bed80500 160 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 66 147 2.7E-47 T 15-10-2018 IPR014099 Spore coat protein GerQ C2I28_07600 f960a7581b0d5675887f0a96bed80500 160 Pfam PF09671 Spore coat protein (Spore_GerQ) 68 143 2.2E-42 T 15-10-2018 IPR014099 Spore coat protein GerQ C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 9 26 5.9E-36 T 15-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 26 42 5.9E-36 T 15-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 58 74 5.9E-36 T 15-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 42 58 5.9E-36 T 15-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 Gene3D G3DSA:2.60.40.50 1 76 8.8E-42 T 15-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 73 28.816 T 15-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 SUPERFAMILY SSF51219 8 74 1.91E-35 T 15-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily C2I28_03230 f270d849be4797bb15f0f9a4cb777c4e 76 Pfam PF02081 Tryptophan RNA-binding attenuator protein 8 73 9.8E-41 T 15-10-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain C2I28_20595 8ccebe7d3e9e7194e8fade3a16469987 218 Gene3D G3DSA:3.90.1470.20 15 132 1.4E-47 T 15-10-2018 C2I28_20595 8ccebe7d3e9e7194e8fade3a16469987 218 Gene3D G3DSA:3.40.50.1000 7 206 1.4E-47 T 15-10-2018 IPR023214 HAD superfamily C2I28_20595 8ccebe7d3e9e7194e8fade3a16469987 218 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 174 4.9E-27 T 15-10-2018 C2I28_20595 8ccebe7d3e9e7194e8fade3a16469987 218 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 169 8.4E-12 T 15-10-2018 C2I28_20595 8ccebe7d3e9e7194e8fade3a16469987 218 SUPERFAMILY SSF56784 1 209 2.59E-38 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_20595 8ccebe7d3e9e7194e8fade3a16469987 218 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 183 5.6E-41 T 15-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 C2I28_14290 0602ef7ed7f4c4f0ee4b70c299e9729d 260 Pfam PF00795 Carbon-nitrogen hydrolase 5 247 1.4E-44 T 15-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 C2I28_14290 0602ef7ed7f4c4f0ee4b70c299e9729d 260 SUPERFAMILY SSF56317 3 260 8.89E-71 T 15-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I28_14290 0602ef7ed7f4c4f0ee4b70c299e9729d 260 Gene3D G3DSA:3.60.110.10 1 260 3.2E-89 T 15-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I28_00380 89c75c909a8265584ed5712882033345 136 SUPERFAMILY SSF51182 11 133 4.0E-27 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_00380 89c75c909a8265584ed5712882033345 136 Pfam PF07883 Cupin domain 48 108 2.9E-8 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_00380 89c75c909a8265584ed5712882033345 136 Gene3D G3DSA:2.60.120.10 1 136 1.1E-45 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_13190 d44f7d593b4f15f251dbf494b04cd7d7 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 76 9.9E-19 T 15-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I28_13190 d44f7d593b4f15f251dbf494b04cd7d7 284 SUPERFAMILY SSF46689 5 76 3.94E-19 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_13190 d44f7d593b4f15f251dbf494b04cd7d7 284 Gene3D G3DSA:3.40.50.10490 98 283 9.9E-45 T 15-10-2018 C2I28_13190 d44f7d593b4f15f251dbf494b04cd7d7 284 Pfam PF01380 SIS domain 130 258 7.2E-24 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_13190 d44f7d593b4f15f251dbf494b04cd7d7 284 SUPERFAMILY SSF53697 100 268 1.57E-39 T 15-10-2018 C2I28_13190 d44f7d593b4f15f251dbf494b04cd7d7 284 Gene3D G3DSA:1.10.10.10 2 82 3.7E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_10050 85f520761fe8d0a10417a99d42d6d237 375 SUPERFAMILY SSF51338 3 372 2.74E-26 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_10050 85f520761fe8d0a10417a99d42d6d237 375 Gene3D G3DSA:2.30.40.10 6 368 2.0E-109 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_10050 85f520761fe8d0a10417a99d42d6d237 375 Gene3D G3DSA:3.20.20.140 57 334 2.0E-109 T 15-10-2018 C2I28_10050 85f520761fe8d0a10417a99d42d6d237 375 Pfam PF01979 Amidohydrolase family 53 370 3.0E-21 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_10050 85f520761fe8d0a10417a99d42d6d237 375 SUPERFAMILY SSF51556 56 338 1.5E-42 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_02765 9a68fca448b8227706c8fb7819209229 312 Gene3D G3DSA:3.40.50.170 1 205 7.4E-85 T 15-10-2018 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 302 36.203 T 15-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 Pfam PF00551 Formyl transferase 1 179 5.3E-39 T 15-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 15-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 Pfam PF02911 Formyl transferase, C-terminal domain 203 298 8.0E-28 T 15-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 Gene3D G3DSA:3.10.25.10 206 310 1.3E-39 T 15-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 SUPERFAMILY SSF50486 204 307 1.73E-31 T 15-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 SUPERFAMILY SSF53328 1 205 8.37E-67 T 15-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_02765 9a68fca448b8227706c8fb7819209229 312 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 304 2.6E-111 T 15-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 C2I28_04840 953087c392f4233ef3bfab72e9fa0a66 178 SMART SM01317 59 173 1.9E-21 T 15-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal C2I28_04840 953087c392f4233ef3bfab72e9fa0a66 178 Gene3D G3DSA:1.10.287.130 1 57 3.5E-23 T 15-10-2018 C2I28_04840 953087c392f4233ef3bfab72e9fa0a66 178 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 4 57 4.0E-21 T 15-10-2018 IPR039506 SpoOB, alpha-helical domain C2I28_04840 953087c392f4233ef3bfab72e9fa0a66 178 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 62 171 1.2E-27 T 15-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal C2I28_04840 953087c392f4233ef3bfab72e9fa0a66 178 SUPERFAMILY SSF55890 1 151 1.31E-40 T 15-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I28_04840 953087c392f4233ef3bfab72e9fa0a66 178 Gene3D G3DSA:3.30.565.30 58 176 2.5E-31 T 15-10-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily C2I28_19465 d9f7b9eef48f58b4e296d121cc84ae15 273 SUPERFAMILY SSF56281 17 234 2.1E-27 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_19465 d9f7b9eef48f58b4e296d121cc84ae15 273 SMART SM00849 18 206 9.1E-9 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_19465 d9f7b9eef48f58b4e296d121cc84ae15 273 Gene3D G3DSA:3.60.15.10 3 225 5.0E-27 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_26900 20d8441d7d82a72df2ca0dd371347dcd 405 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 100 114 2.5E-5 T 15-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 C2I28_26900 20d8441d7d82a72df2ca0dd371347dcd 405 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 271 283 2.5E-5 T 15-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 C2I28_26900 20d8441d7d82a72df2ca0dd371347dcd 405 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 77 93 2.5E-5 T 15-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 C2I28_26900 20d8441d7d82a72df2ca0dd371347dcd 405 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 77 363 7.2E-22 T 15-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 C2I28_26900 20d8441d7d82a72df2ca0dd371347dcd 405 SUPERFAMILY SSF53335 73 361 1.12E-30 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_26900 20d8441d7d82a72df2ca0dd371347dcd 405 Gene3D G3DSA:3.40.50.150 71 255 2.9E-6 T 15-10-2018 C2I28_07370 8c5bc1c3273df7671eb7bc322c7eb5ba 209 Gene3D G3DSA:3.40.50.2020 1 209 1.2E-84 T 15-10-2018 C2I28_07370 8c5bc1c3273df7671eb7bc322c7eb5ba 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.724 T 15-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 C2I28_07370 8c5bc1c3273df7671eb7bc322c7eb5ba 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 6.9E-76 T 15-10-2018 C2I28_07370 8c5bc1c3273df7671eb7bc322c7eb5ba 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.8E-93 T 15-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 C2I28_07370 8c5bc1c3273df7671eb7bc322c7eb5ba 209 SUPERFAMILY SSF53271 4 207 3.28E-75 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_25160 799eea618814bdf57cae986fc1e1d2e0 417 SUPERFAMILY SSF159501 14 411 5.49E-60 T 15-10-2018 C2I28_25160 799eea618814bdf57cae986fc1e1d2e0 417 Gene3D G3DSA:1.20.1440.30 142 283 4.0E-41 T 15-10-2018 C2I28_25160 799eea618814bdf57cae986fc1e1d2e0 417 Gene3D G3DSA:3.30.1870.10 75 141 4.0E-41 T 15-10-2018 C2I28_25160 799eea618814bdf57cae986fc1e1d2e0 417 Gene3D G3DSA:3.40.1660.10 17 383 4.0E-41 T 15-10-2018 C2I28_25160 799eea618814bdf57cae986fc1e1d2e0 417 Pfam PF05139 Erythromycin esterase 73 404 1.9E-32 T 15-10-2018 IPR007815 Erythromycin esterase GO:0046677 C2I28_16095 dc852243e5515980fbe662ddac35c989 193 SUPERFAMILY SSF46785 1 191 1.2E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16095 dc852243e5515980fbe662ddac35c989 193 SMART SM00418 8 82 3.4E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16095 dc852243e5515980fbe662ddac35c989 193 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 118 182 7.0E-22 T 15-10-2018 IPR018656 Domain of unknown function DUF2087 C2I28_16095 dc852243e5515980fbe662ddac35c989 193 Gene3D G3DSA:1.10.10.10 1 90 3.0E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16095 dc852243e5515980fbe662ddac35c989 193 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 8.1E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 Gene3D G3DSA:3.40.50.12740 3 211 2.1E-77 T 15-10-2018 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 SMART SM00448 3 116 8.3E-35 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 SUPERFAMILY SSF52172 1 133 8.11E-37 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_20615 8a592e79b84d6427547443c136bb485d 212 SUPERFAMILY SSF46894 137 211 5.44E-23 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 SMART SM00421 149 206 9.3E-28 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 8.7E-23 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.1E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.1E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.1E-15 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_20615 8a592e79b84d6427547443c136bb485d 212 Pfam PF00072 Response regulator receiver domain 5 117 2.4E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_20015 ccf37161880e1bec0042ee07b0f833e2 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 4.0E-26 T 15-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_20015 ccf37161880e1bec0042ee07b0f833e2 89 SUPERFAMILY SSF57716 2 89 9.27E-31 T 15-10-2018 C2I28_20015 ccf37161880e1bec0042ee07b0f833e2 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 15-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_20015 ccf37161880e1bec0042ee07b0f833e2 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 24.775 T 15-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid C2I28_20015 ccf37161880e1bec0042ee07b0f833e2 89 Gene3D G3DSA:4.10.830.10 1 89 3.9E-24 T 15-10-2018 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 SMART SM00345 8 67 1.7E-16 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 SUPERFAMILY SSF53822 82 358 3.14E-59 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 Gene3D G3DSA:3.40.50.2300 187 352 2.2E-79 T 15-10-2018 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 SUPERFAMILY SSF46785 3 71 9.99E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 Gene3D G3DSA:1.10.10.10 1 68 1.1E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 3.2E-7 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 3.2E-7 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 Gene3D G3DSA:3.40.50.2300 84 349 2.2E-79 T 15-10-2018 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 Pfam PF13377 Periplasmic binding protein-like domain 196 356 2.7E-28 T 15-10-2018 C2I28_25585 35d6111bf1b21dadbe4b33d5294e3c81 368 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 1.0E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.4E-22 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 SUPERFAMILY SSF46785 2 86 8.47E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 Gene3D G3DSA:3.40.190.10 162 268 9.9E-28 T 15-10-2018 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.1E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.1E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.1E-10 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 SUPERFAMILY SSF53850 90 298 7.47E-26 T 15-10-2018 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 Pfam PF03466 LysR substrate binding domain 89 294 3.6E-24 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 Gene3D G3DSA:3.40.190.10 91 288 9.9E-28 T 15-10-2018 C2I28_00360 2cf323f2570cb5e11343cf5a1d442be5 300 Gene3D G3DSA:1.10.10.10 1 90 1.5E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14465 97368d1975b2ee908e48274710db5595 237 Pfam PF07486 Cell Wall Hydrolase 134 235 3.0E-23 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_14465 97368d1975b2ee908e48274710db5595 237 Gene3D G3DSA:3.10.350.10 22 88 2.7E-15 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_14465 97368d1975b2ee908e48274710db5595 237 SMART SM00257 31 74 1.8E-11 T 15-10-2018 IPR018392 LysM domain C2I28_14465 97368d1975b2ee908e48274710db5595 237 Gene3D G3DSA:2.40.10.420 202 237 1.9E-14 T 15-10-2018 C2I28_14465 97368d1975b2ee908e48274710db5595 237 Pfam PF01476 LysM domain 32 74 5.6E-12 T 15-10-2018 IPR018392 LysM domain C2I28_14465 97368d1975b2ee908e48274710db5595 237 SUPERFAMILY SSF54106 31 74 1.44E-10 T 15-10-2018 C2I28_14465 97368d1975b2ee908e48274710db5595 237 Gene3D G3DSA:1.10.10.2520 118 200 3.9E-27 T 15-10-2018 C2I28_12675 036064fd7b8954ae9549268084c5f662 777 Pfam PF12698 ABC-2 family transporter protein 534 757 1.6E-14 T 15-10-2018 C2I28_12675 036064fd7b8954ae9549268084c5f662 777 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 560 761 4.5E-62 T 15-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal C2I28_12675 036064fd7b8954ae9549268084c5f662 777 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 7 169 2.1E-65 T 15-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal C2I28_12675 036064fd7b8954ae9549268084c5f662 777 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 460 485 2.7E-4 T 15-10-2018 IPR023908 xxxLxxG heptad repeat C2I28_12675 036064fd7b8954ae9549268084c5f662 777 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 514 540 3.8E-6 T 15-10-2018 IPR023908 xxxLxxG heptad repeat C2I28_12675 036064fd7b8954ae9549268084c5f662 777 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 173 198 5.7E-6 T 15-10-2018 IPR023908 xxxLxxG heptad repeat C2I28_12675 036064fd7b8954ae9549268084c5f662 777 Pfam PF12051 Protein of unknown function (DUF3533) 27 180 8.2E-11 T 15-10-2018 IPR022703 Domain of unknown function DUF3533 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 Gene3D G3DSA:3.30.870.10 35 234 1.6E-31 T 15-10-2018 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 Gene3D G3DSA:3.30.870.10 258 432 5.8E-26 T 15-10-2018 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 SUPERFAMILY SSF56024 58 216 7.18E-26 T 15-10-2018 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 SMART SM00155 144 171 2.7 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 SMART SM00155 364 391 0.021 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 Pfam PF13091 PLD-like domain 61 190 1.1E-16 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 Pfam PF13091 PLD-like domain 293 412 1.4E-14 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_19205 9573bb0d00a98b4f2f897f03bc017396 464 SUPERFAMILY SSF56024 272 425 1.95E-19 T 15-10-2018 C2I28_01630 d2e80ba9da4a5c7cfee86acb0490d348 169 Gene3D G3DSA:3.40.630.30 1 168 1.2E-43 T 15-10-2018 C2I28_01630 d2e80ba9da4a5c7cfee86acb0490d348 169 Pfam PF00583 Acetyltransferase (GNAT) family 31 140 8.7E-19 T 15-10-2018 IPR000182 GNAT domain C2I28_01630 d2e80ba9da4a5c7cfee86acb0490d348 169 SUPERFAMILY SSF55729 1 164 4.22E-30 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 5.6E-6 T 15-10-2018 C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 5.6E-6 T 15-10-2018 C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 5.6E-6 T 15-10-2018 C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 Gene3D G3DSA:3.40.50.720 3 273 3.4E-142 T 15-10-2018 C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 SUPERFAMILY SSF51735 1 335 3.5E-93 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 Gene3D G3DSA:3.90.25.10 193 328 3.4E-142 T 15-10-2018 C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 1.4E-137 T 15-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 C2I28_18875 56fe40a4de38d2215a31772562f8f779 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 6.3E-58 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_16210 fede080592a8edd7edfa3379493d27f5 145 Gene3D G3DSA:3.90.79.10 3 144 1.6E-17 T 15-10-2018 C2I28_16210 fede080592a8edd7edfa3379493d27f5 145 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 15-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I28_16210 fede080592a8edd7edfa3379493d27f5 145 SUPERFAMILY SSF55811 11 136 5.01E-17 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_16210 fede080592a8edd7edfa3379493d27f5 145 PRINTS PR00502 NUDIX hydrolase family signature 37 51 6.7E-6 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_16210 fede080592a8edd7edfa3379493d27f5 145 PRINTS PR00502 NUDIX hydrolase family signature 51 66 6.7E-6 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_16210 fede080592a8edd7edfa3379493d27f5 145 Pfam PF00293 NUDIX domain 17 136 1.1E-14 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.504 T 15-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 SMART SM00962 120 321 1.2E-124 T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 SMART SM00963 22 103 2.5E-27 T 15-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 Gene3D G3DSA:1.20.120.140 20 317 2.6E-117 T 15-10-2018 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 SUPERFAMILY SSF52540 115 318 9.59E-53 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 SMART SM00382 119 297 2.2E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 47 320 1.2E-120 T 15-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 5.6E-15 T 15-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 SUPERFAMILY SSF47364 18 96 7.2E-22 T 15-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 7.5E-83 T 15-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 C2I28_02650 61b7f6b2552e196d78baeefdca573cff 332 Gene3D G3DSA:3.40.50.300 116 309 2.6E-117 T 15-10-2018 C2I28_16960 7a5a55027a54eebcec219f37ca5dfdf9 320 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 29 305 2.0E-68 T 15-10-2018 IPR015402 Protein of unknown function DUF1980 C2I28_16960 7a5a55027a54eebcec219f37ca5dfdf9 320 Pfam PF09323 Domain of unknown function (DUF1980) 11 217 4.4E-45 T 15-10-2018 IPR015402 Protein of unknown function DUF1980 C2I28_21545 36356363eedac23c87bea03588897240 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.3E-6 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21545 36356363eedac23c87bea03588897240 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.3E-6 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21545 36356363eedac23c87bea03588897240 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.3E-6 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21545 36356363eedac23c87bea03588897240 145 Gene3D G3DSA:1.10.10.10 3 138 4.1E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_21545 36356363eedac23c87bea03588897240 145 SMART SM00347 22 123 8.9E-18 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21545 36356363eedac23c87bea03588897240 145 Pfam PF01047 MarR family 32 87 2.1E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21545 36356363eedac23c87bea03588897240 145 SUPERFAMILY SSF46785 18 137 1.93E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04595 ce5df0a72854dedf2633a96e636009b2 138 Gene3D G3DSA:3.30.420.140 1 138 1.5E-50 T 15-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 C2I28_04595 ce5df0a72854dedf2633a96e636009b2 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 7.0E-52 T 15-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 C2I28_04595 ce5df0a72854dedf2633a96e636009b2 138 SMART SM00732 1 103 1.1E-37 T 15-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 C2I28_04595 ce5df0a72854dedf2633a96e636009b2 138 SUPERFAMILY SSF53098 1 137 1.97E-45 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_04595 ce5df0a72854dedf2633a96e636009b2 138 Pfam PF03652 Holliday junction resolvase 1 136 5.7E-46 T 15-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 C2I28_04595 ce5df0a72854dedf2633a96e636009b2 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 27.37 T 15-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 C2I28_13760 20ca661e29027150cedeb43c720e94cd 395 Gene3D G3DSA:3.90.550.10 1 270 1.8E-50 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13760 20ca661e29027150cedeb43c720e94cd 395 Pfam PF00535 Glycosyl transferase family 2 7 152 9.1E-34 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_13760 20ca661e29027150cedeb43c720e94cd 395 SUPERFAMILY SSF53448 4 225 4.22E-52 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_17280 870a1a6b38cdb91435aef742f219239b 539 SUPERFAMILY SSF56801 20 532 1.7E-148 T 15-10-2018 C2I28_17280 870a1a6b38cdb91435aef742f219239b 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_17280 870a1a6b38cdb91435aef742f219239b 539 Gene3D G3DSA:3.40.50.12780 14 432 1.1E-122 T 15-10-2018 C2I28_17280 870a1a6b38cdb91435aef742f219239b 539 Pfam PF00501 AMP-binding enzyme 31 436 2.4E-108 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_17280 870a1a6b38cdb91435aef742f219239b 539 Gene3D G3DSA:3.30.300.310 433 536 2.8E-31 T 15-10-2018 C2I28_17280 870a1a6b38cdb91435aef742f219239b 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 520 6.1E-19 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 SUPERFAMILY SSF54106 77 120 1.44E-12 T 15-10-2018 C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 SUPERFAMILY SSF50685 262 310 1.71E-9 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 Pfam PF01476 LysM domain 79 120 1.8E-15 T 15-10-2018 IPR018392 LysM domain C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 Pfam PF01476 LysM domain 30 71 9.3E-13 T 15-10-2018 IPR018392 LysM domain C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 Gene3D G3DSA:3.10.350.10 25 75 7.7E-18 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 Gene3D G3DSA:3.10.350.10 76 129 1.7E-20 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 SMART SM00257 78 121 3.0E-17 T 15-10-2018 IPR018392 LysM domain C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 SMART SM00257 29 72 7.6E-14 T 15-10-2018 IPR018392 LysM domain C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 Gene3D G3DSA:2.40.40.10 131 315 4.0E-7 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 Pfam PF06725 3D domain 261 321 2.8E-21 T 15-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I28_22975 4491422ca3b0c59cb5d0aff14c701539 322 SUPERFAMILY SSF54106 29 71 2.49E-11 T 15-10-2018 C2I28_14900 340d12448a0633ae2d8bb504b71e6fa2 312 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 87 109 - T 15-10-2018 IPR030470 UbiA prenyltransferase conserved site C2I28_14900 340d12448a0633ae2d8bb504b71e6fa2 312 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 30 308 6.2E-93 T 15-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 C2I28_14900 340d12448a0633ae2d8bb504b71e6fa2 312 Gene3D G3DSA:1.10.357.140 39 195 1.7E-14 T 15-10-2018 C2I28_14900 340d12448a0633ae2d8bb504b71e6fa2 312 Pfam PF01040 UbiA prenyltransferase family 46 294 2.1E-56 T 15-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 C2I28_14900 340d12448a0633ae2d8bb504b71e6fa2 312 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 27 310 17.894 T 15-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 202 1.9E-23 T 15-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Gene3D G3DSA:3.40.710.10 283 478 2.8E-110 T 15-10-2018 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 4.4E-85 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Gene3D G3DSA:3.90.1310.30 49 220 4.7E-45 T 15-10-2018 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Gene3D G3DSA:3.30.450.330 222 561 2.8E-110 T 15-10-2018 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 SMART SM00740 580 638 8.5E-17 T 15-10-2018 IPR005543 PASTA domain C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Pfam PF03793 PASTA domain 584 638 4.2E-13 T 15-10-2018 IPR005543 PASTA domain C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 SUPERFAMILY SSF56519 51 220 1.7E-43 T 15-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 12 637 4.4E-270 T 15-10-2018 IPR011927 Stage V sporulation protein D C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 Gene3D G3DSA:3.30.10.20 582 638 4.3E-10 T 15-10-2018 C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 SUPERFAMILY SSF56601 171 568 2.73E-99 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_02975 9e5999e2b6b91a0e373836a0ff45782a 638 SUPERFAMILY SSF54184 584 637 5.1E-12 T 15-10-2018 C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 324 5.0E-45 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 SUPERFAMILY SSF51905 3 209 1.21E-29 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 Gene3D G3DSA:3.50.50.100 1 404 6.4E-139 T 15-10-2018 C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 SUPERFAMILY SSF51905 151 337 5.66E-22 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.3E-6 T 15-10-2018 C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 8.3E-6 T 15-10-2018 C2I28_06380 cc8c0870d05fc38c51171d810929f1a3 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 8.3E-6 T 15-10-2018 C2I28_17485 617b448df8342d12bab0eb81a741c5e4 139 PRINTS PR01438 Universal stress protein signature 2 20 9.2E-20 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17485 617b448df8342d12bab0eb81a741c5e4 139 PRINTS PR01438 Universal stress protein signature 99 111 9.2E-20 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17485 617b448df8342d12bab0eb81a741c5e4 139 PRINTS PR01438 Universal stress protein signature 117 139 9.2E-20 T 15-10-2018 IPR006015 Universal stress protein A C2I28_17485 617b448df8342d12bab0eb81a741c5e4 139 SUPERFAMILY SSF52402 1 139 2.36E-33 T 15-10-2018 C2I28_17485 617b448df8342d12bab0eb81a741c5e4 139 Gene3D G3DSA:3.40.50.620 1 139 5.9E-36 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_17485 617b448df8342d12bab0eb81a741c5e4 139 Pfam PF00582 Universal stress protein family 1 139 8.8E-29 T 15-10-2018 IPR006016 UspA C2I28_03735 52f5e13869636cde8ee4c65e31ea8049 331 Pfam PF03308 ArgK protein 21 290 3.0E-91 T 15-10-2018 C2I28_03735 52f5e13869636cde8ee4c65e31ea8049 331 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 16 319 3.2E-92 T 15-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_03735 52f5e13869636cde8ee4c65e31ea8049 331 Gene3D G3DSA:3.40.50.300 50 261 6.4E-70 T 15-10-2018 C2I28_03735 52f5e13869636cde8ee4c65e31ea8049 331 SUPERFAMILY SSF52540 2 324 3.15E-81 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03735 52f5e13869636cde8ee4c65e31ea8049 331 Gene3D G3DSA:1.20.5.170 1 49 3.3E-17 T 15-10-2018 C2I28_03735 52f5e13869636cde8ee4c65e31ea8049 331 Gene3D G3DSA:1.10.287.130 263 327 4.9E-14 T 15-10-2018 C2I28_03645 8eef5c00bae4ba683ca982e99d9ea820 309 Gene3D G3DSA:3.60.15.10 1 308 1.4E-100 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_03645 8eef5c00bae4ba683ca982e99d9ea820 309 Pfam PF00753 Metallo-beta-lactamase superfamily 25 99 6.4E-9 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_03645 8eef5c00bae4ba683ca982e99d9ea820 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 307 8.7E-115 T 15-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 C2I28_03645 8eef5c00bae4ba683ca982e99d9ea820 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 308 41.281 T 15-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 C2I28_03645 8eef5c00bae4ba683ca982e99d9ea820 309 SUPERFAMILY SSF56281 1 308 6.42E-80 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_02645 5c5b294aeb6389c986c79782589f88cb 117 SUPERFAMILY SSF88659 8 102 3.55E-34 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_02645 5c5b294aeb6389c986c79782589f88cb 117 Hamap MF_00245 UPF0122 protein . 9 110 22.174 T 15-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like C2I28_02645 5c5b294aeb6389c986c79782589f88cb 117 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 9 105 6.4E-41 T 15-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like C2I28_02645 5c5b294aeb6389c986c79782589f88cb 117 Gene3D G3DSA:1.10.10.10 5 117 7.0E-38 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17095 969b5746aaf1442f6b27506794eaebae 94 Pfam PF17247 Family of unknown function (DUF5316) 37 93 5.9E-11 T 15-10-2018 IPR035167 Protein of unknown function DUF5316 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 SUPERFAMILY SSF53254 1 231 2.63E-73 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 43.964 T 15-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 233 2.5E-105 T 15-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 15-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 SMART SM00855 3 189 1.2E-25 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 Gene3D G3DSA:3.40.50.1240 1 231 4.2E-83 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 144 209 9.4E-5 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 127 2.0E-28 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 PIRSF PIRSF000709 172 224 0.0086 T 15-10-2018 C2I28_10925 0ca5d8840d6e062a4f8c76e751ab8019 241 PIRSF PIRSF000709 3 114 3.1E-8 T 15-10-2018 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 PRINTS PR00149 Fumarate lyase superfamily signature 187 205 4.4E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 PRINTS PR00149 Fumarate lyase superfamily signature 142 160 4.4E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 PRINTS PR00149 Fumarate lyase superfamily signature 278 305 4.4E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 PRINTS PR00149 Fumarate lyase superfamily signature 324 340 4.4E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 Gene3D G3DSA:1.20.200.10 147 414 1.2E-113 T 15-10-2018 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 13 473 1.2E-231 T 15-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 Pfam PF00206 Lyase 20 349 7.8E-110 T 15-10-2018 IPR022761 Fumarate lyase, N-terminal C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 Gene3D G3DSA:1.10.275.10 13 146 4.5E-58 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 Pfam PF10415 Fumarase C C-terminus 415 468 4.1E-19 T 15-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 PRINTS PR00145 Argininosuccinate lyase family signature 182 202 3.3E-6 T 15-10-2018 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 PRINTS PR00145 Argininosuccinate lyase family signature 324 340 3.3E-6 T 15-10-2018 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 Gene3D G3DSA:1.10.40.30 415 466 2.8E-21 T 15-10-2018 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 ProSitePatterns PS00163 Fumarate lyases signature. 324 333 - T 15-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I28_16900 d9ac28dbef3267ab7a2c4363f07449e1 480 SUPERFAMILY SSF48557 13 469 7.23E-146 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_20865 d17aeb3fc6c708be1e92a59e092ef82d 140 Pfam PF03061 Thioesterase superfamily 18 102 8.8E-16 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_20865 d17aeb3fc6c708be1e92a59e092ef82d 140 PIRSF PIRSF003230 2 137 7.4E-33 T 15-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 C2I28_20865 d17aeb3fc6c708be1e92a59e092ef82d 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 1.7E-37 T 15-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 C2I28_20865 d17aeb3fc6c708be1e92a59e092ef82d 140 SUPERFAMILY SSF54637 5 133 9.27E-41 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_20865 d17aeb3fc6c708be1e92a59e092ef82d 140 Gene3D G3DSA:3.10.129.10 3 128 1.1E-37 T 15-10-2018 C2I28_13400 d43ac8685a5202cbbae148cb87b13297 490 Pfam PF00474 Sodium:solute symporter family 35 428 1.8E-22 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_13400 d43ac8685a5202cbbae148cb87b13297 490 Gene3D G3DSA:1.20.1730.10 21 490 1.2E-34 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_07730 00ec9769f5c04d298d5f797e4675d6a9 468 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 443 4.8E-172 T 15-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I28_07730 00ec9769f5c04d298d5f797e4675d6a9 468 PIRSF PIRSF006446 1 468 1.9E-178 T 15-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 Gene3D G3DSA:3.30.1360.40 1 96 1.2E-26 T 15-10-2018 C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 SUPERFAMILY SSF160467 6 104 4.58E-17 T 15-10-2018 C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 10 222 1.1E-76 T 15-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 SUPERFAMILY SSF50891 100 229 1.1E-48 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 SMART SM00796 5 213 9.6E-99 T 15-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 6 213 1.5E-74 T 15-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D C2I28_12960 cd6fbce233777caf45fb22d76dd0ab94 240 Gene3D G3DSA:2.40.100.10 98 237 1.3E-60 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 Gene3D G3DSA:3.90.45.10 1 156 1.2E-57 T 15-10-2018 IPR036821 Peptide deformylase superfamily C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 PRINTS PR01576 Peptide deformylase signature 88 99 2.7E-34 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 PRINTS PR01576 Peptide deformylase signature 119 148 2.7E-34 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 PRINTS PR01576 Peptide deformylase signature 33 62 2.7E-34 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 PRINTS PR01576 Peptide deformylase signature 100 118 2.7E-34 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 Hamap MF_00163 Peptide deformylase [def]. 2 155 26.724 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 154 1.4E-50 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 Pfam PF01327 Polypeptide deformylase 5 148 2.5E-46 T 15-10-2018 IPR023635 Peptide deformylase C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 SUPERFAMILY SSF56420 4 149 2.22E-51 T 15-10-2018 IPR036821 Peptide deformylase superfamily C2I28_02770 409eadc0e2f878aeeb3f2157e126a19c 157 PIRSF PIRSF004749 1 155 5.6E-46 T 15-10-2018 IPR023635 Peptide deformylase C2I28_00715 f37ad6674601435496085fc45a344fed 37 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 31 2.1E-13 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_00715 f37ad6674601435496085fc45a344fed 37 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 29 3.4E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_04530 a9cb657ec1063ad0e6d9940c70a64f38 231 Gene3D G3DSA:3.40.50.1580 1 231 1.5E-71 T 15-10-2018 C2I28_04530 a9cb657ec1063ad0e6d9940c70a64f38 231 Pfam PF01048 Phosphorylase superfamily 2 227 1.3E-53 T 15-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I28_04530 a9cb657ec1063ad0e6d9940c70a64f38 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 48.053 T 15-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_04530 a9cb657ec1063ad0e6d9940c70a64f38 231 SUPERFAMILY SSF53167 1 230 1.7E-73 T 15-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I28_04530 a9cb657ec1063ad0e6d9940c70a64f38 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 230 4.1E-114 T 15-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 C2I28_09205 3346dc64558881ce6a70c72cc4405c81 149 Pfam PF10263 SprT-like family 9 97 9.8E-14 T 15-10-2018 IPR006640 SprT-like C2I28_09205 3346dc64558881ce6a70c72cc4405c81 149 SMART SM00731 4 149 1.5E-53 T 15-10-2018 IPR006640 SprT-like C2I28_09205 3346dc64558881ce6a70c72cc4405c81 149 Hamap MF_00745 Protein SprT-like. 4 149 38.377 T 15-10-2018 IPR023524 Uncharacterised protein family SprT-like C2I28_09205 3346dc64558881ce6a70c72cc4405c81 149 Pfam PF17283 SprT-like zinc ribbon domain 116 147 1.7E-7 T 15-10-2018 IPR035240 SprT-like, zinc ribbon domain C2I28_05585 9b54b1e347ebe817a565b88b5fbf7e88 264 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 260 3.6E-70 T 15-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 C2I28_05585 9b54b1e347ebe817a565b88b5fbf7e88 264 Gene3D G3DSA:3.20.20.140 1 263 2.4E-66 T 15-10-2018 C2I28_05585 9b54b1e347ebe817a565b88b5fbf7e88 264 Pfam PF02811 PHP domain 5 180 9.3E-12 T 15-10-2018 IPR004013 PHP domain GO:0003824 C2I28_05585 9b54b1e347ebe817a565b88b5fbf7e88 264 SUPERFAMILY SSF89550 1 259 1.44E-35 T 15-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I28_05585 9b54b1e347ebe817a565b88b5fbf7e88 264 Pfam PF13263 PHP-associated 233 261 8.5E-5 T 15-10-2018 C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 SUPERFAMILY SSF88946 2 102 2.62E-14 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 Gene3D G3DSA:1.10.10.10 89 170 1.9E-10 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 Pfam PF08281 Sigma-70, region 4 113 165 9.7E-11 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 Gene3D G3DSA:1.10.1740.10 5 86 3.5E-14 T 15-10-2018 C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 Pfam PF04542 Sigma-70 region 2 21 87 1.3E-10 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 SUPERFAMILY SSF88659 115 170 1.7E-10 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_25665 eb29598a5d24f6cfd6fae920683fd867 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 166 1.2E-23 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_25580 9fa8611fefad405eb5d140e5826e8c89 543 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 279 476 1.6E-33 T 15-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 C2I28_25580 9fa8611fefad405eb5d140e5826e8c89 543 SUPERFAMILY SSF53067 275 521 8.2E-14 T 15-10-2018 C2I28_25580 9fa8611fefad405eb5d140e5826e8c89 543 Gene3D G3DSA:3.30.420.40 267 535 5.9E-18 T 15-10-2018 C2I28_25580 9fa8611fefad405eb5d140e5826e8c89 543 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 19 263 2.0E-18 T 15-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 C2I28_25580 9fa8611fefad405eb5d140e5826e8c89 543 Gene3D G3DSA:3.30.420.40 13 266 4.9E-38 T 15-10-2018 C2I28_25580 9fa8611fefad405eb5d140e5826e8c89 543 SUPERFAMILY SSF53067 18 265 7.43E-33 T 15-10-2018 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 SUPERFAMILY SSF56104 2 233 1.96E-82 T 15-10-2018 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 Pfam PF01259 SAICAR synthetase 7 232 5.7E-67 T 15-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 Gene3D G3DSA:3.30.470.20 85 221 5.1E-98 T 15-10-2018 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 Gene3D G3DSA:3.30.200.20 7 232 5.1E-98 T 15-10-2018 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 233 6.1E-77 T 15-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 15-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 32.783 T 15-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_09440 6385e704b7a3f3acbd476d4d44b2534b 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 15-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 C2I28_17850 4ece26f3c2b5fb5acbea652f017b1114 266 Gene3D G3DSA:3.40.1440.10 15 115 4.7E-14 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_17850 4ece26f3c2b5fb5acbea652f017b1114 266 SMART SM00465 28 110 1.5E-4 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_17850 4ece26f3c2b5fb5acbea652f017b1114 266 Pfam PF01541 GIY-YIG catalytic domain 30 90 2.0E-6 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_17850 4ece26f3c2b5fb5acbea652f017b1114 266 SUPERFAMILY SSF82771 28 107 2.88E-9 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_12405 15f533f05ff00e46a51d02e8e41368d1 642 Pfam PF00884 Sulfatase 245 536 1.7E-31 T 15-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I28_12405 15f533f05ff00e46a51d02e8e41368d1 642 SUPERFAMILY SSF53649 243 634 1.16E-76 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_12405 15f533f05ff00e46a51d02e8e41368d1 642 PIRSF PIRSF005091 1 620 1.7E-192 T 15-10-2018 IPR012160 Lipoteichoic acid synthase-like C2I28_12405 15f533f05ff00e46a51d02e8e41368d1 642 Gene3D G3DSA:3.40.720.10 237 546 2.3E-76 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_00100 772a06ec7c2b614a94bf0318a12279ca 214 Gene3D G3DSA:3.40.50.850 1 209 4.0E-54 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_00100 772a06ec7c2b614a94bf0318a12279ca 214 SUPERFAMILY SSF52499 5 203 2.75E-54 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_00100 772a06ec7c2b614a94bf0318a12279ca 214 Pfam PF00857 Isochorismatase family 14 165 2.9E-23 T 15-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I28_23340 e9469a0bfa189875933f2e41155efb8a 153 Gene3D G3DSA:1.20.120.450 1 143 4.6E-35 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_23340 e9469a0bfa189875933f2e41155efb8a 153 SUPERFAMILY SSF109854 2 147 9.31E-31 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_23340 e9469a0bfa189875933f2e41155efb8a 153 Pfam PF05163 DinB family 4 147 2.8E-23 T 15-10-2018 IPR007837 DNA damage-inducible protein DinB C2I28_14700 7ee7fbf348e4feeac6de0cf4ca76b2dd 81 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 5.0E-15 T 15-10-2018 IPR005370 Uncharacterised protein family UPF0180 C2I28_14700 7ee7fbf348e4feeac6de0cf4ca76b2dd 81 Hamap MF_00506 UPF0180 protein . 1 79 28.132 T 15-10-2018 IPR005370 Uncharacterised protein family UPF0180 C2I28_14700 7ee7fbf348e4feeac6de0cf4ca76b2dd 81 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 78 2.4E-29 T 15-10-2018 IPR005370 Uncharacterised protein family UPF0180 C2I28_26835 2fac623993ac93d2a4a8844379811690 288 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 245 2.2E-64 T 15-10-2018 C2I28_26835 2fac623993ac93d2a4a8844379811690 288 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 285 1.2E-71 T 15-10-2018 IPR010106 Recombination-promoting nuclease RpnA C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 SUPERFAMILY SSF53822 61 330 2.16E-82 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 Pfam PF13377 Periplasmic binding protein-like domain 167 330 9.9E-39 T 15-10-2018 C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 SUPERFAMILY SSF47413 1 56 2.47E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 SMART SM00354 1 71 8.1E-38 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.3E-22 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 Gene3D G3DSA:3.40.50.2300 159 290 4.6E-79 T 15-10-2018 C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 Gene3D G3DSA:3.40.50.2300 62 309 4.6E-79 T 15-10-2018 C2I28_00210 a7fc8c3383addb73b215d90f062a4328 330 Gene3D G3DSA:1.10.260.40 1 59 8.9E-24 T 15-10-2018 C2I28_15985 12d95a6cfa3ade88dd82f10f4109a26d 157 Gene3D G3DSA:3.90.960.10 1 156 1.1E-37 T 15-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I28_15985 12d95a6cfa3ade88dd82f10f4109a26d 157 Pfam PF04073 Aminoacyl-tRNA editing domain 24 142 3.2E-24 T 15-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 C2I28_15985 12d95a6cfa3ade88dd82f10f4109a26d 157 SUPERFAMILY SSF55826 4 152 1.1E-31 T 15-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 4.1E-66 T 15-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 Pfam PF00467 KOW motif 129 159 2.9E-5 T 15-10-2018 IPR005824 KOW C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 Pfam PF02357 Transcription termination factor nusG 3 110 1.5E-28 T 15-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 Gene3D G3DSA:3.30.70.940 1 119 2.0E-44 T 15-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 Gene3D G3DSA:2.30.30.30 120 177 8.8E-24 T 15-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 SMART SM00739 123 150 0.006 T 15-10-2018 IPR005824 KOW C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 SUPERFAMILY SSF82679 2 114 1.44E-40 T 15-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.312 T 15-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 15-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 6.0E-21 T 15-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 6.0E-21 T 15-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 6.0E-21 T 15-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 SMART SM00738 2 113 1.2E-50 T 15-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 C2I28_08615 c87fff5d439dfd8fb820299e9e4d6c0b 177 SUPERFAMILY SSF50104 121 177 1.68E-18 T 15-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 15-10-2018 IPR033135 ClpP, histidine active site C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.202 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 8.5E-54 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 8.5E-54 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 8.5E-54 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 8.5E-54 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 8.5E-54 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 15-10-2018 IPR018215 ClpP, Ser active site C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 SUPERFAMILY SSF52096 10 192 3.42E-73 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 Pfam PF00574 Clp protease 13 192 1.7E-86 T 15-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 1.6E-107 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_06860 c18a6d215dece8b6645de102f4c2a8ac 195 Gene3D G3DSA:3.90.226.10 1 194 1.4E-83 T 15-10-2018 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 SUPERFAMILY SSF53822 62 330 3.44E-79 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.9E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.9E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 Gene3D G3DSA:3.40.50.2300 63 321 3.8E-79 T 15-10-2018 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 Pfam PF13377 Periplasmic binding protein-like domain 171 329 1.3E-33 T 15-10-2018 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 SMART SM00354 2 72 1.2E-35 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.6E-19 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 SUPERFAMILY SSF47413 2 60 1.96E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 Gene3D G3DSA:1.10.260.40 1 60 3.7E-22 T 15-10-2018 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 Gene3D G3DSA:3.40.50.2300 161 326 3.8E-79 T 15-10-2018 C2I28_10585 6d999f6b22e88b93e6c5d4d420a54271 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 15-10-2018 C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 Gene3D G3DSA:1.20.120.530 70 199 2.3E-28 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 SUPERFAMILY SSF46785 5 65 1.45E-11 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 SUPERFAMILY SSF48008 73 197 1.1E-26 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 Pfam PF07729 FCD domain 78 194 6.5E-23 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 66 2.2E-14 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 SMART SM00345 14 68 4.8E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 SMART SM00895 77 195 2.2E-18 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_13815 d4659af8ba05f3f4292ef0be142ba802 208 Gene3D G3DSA:1.10.10.10 9 68 3.1E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 SUPERFAMILY SSF55424 321 442 5.67E-33 T 15-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 4.5E-15 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 4.5E-15 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 4.5E-15 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.5E-15 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 SUPERFAMILY SSF51905 1 313 1.62E-46 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 Gene3D G3DSA:3.50.50.60 113 438 2.3E-148 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 Gene3D G3DSA:3.50.50.60 2 338 2.3E-148 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.0E-20 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.0E-20 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.0E-20 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.0E-20 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.0E-20 T 15-10-2018 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 305 3.9E-65 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_19175 fd4099eefae620c1ac4a389bb0460913 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 428 3.5E-16 T 15-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 C2I28_15720 ae0f48f39b854131d08e91df02f3b62e 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 282 2.8E-65 T 15-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I28_15720 ae0f48f39b854131d08e91df02f3b62e 293 Gene3D G3DSA:3.40.190.100 118 228 4.2E-93 T 15-10-2018 C2I28_15720 ae0f48f39b854131d08e91df02f3b62e 293 Gene3D G3DSA:3.40.190.10 38 292 4.2E-93 T 15-10-2018 C2I28_15720 ae0f48f39b854131d08e91df02f3b62e 293 SUPERFAMILY SSF53850 34 293 8.31E-77 T 15-10-2018 C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 Pfam PF00994 Probable molybdopterin binding domain 18 161 3.0E-36 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 PIRSF PIRSF006443 1 170 3.0E-66 T 15-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 15-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 SMART SM00852 17 162 1.5E-29 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 8.0E-37 T 15-10-2018 IPR001453 MoaB/Mog domain C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 Gene3D G3DSA:3.40.980.10 1 169 3.9E-51 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_00565 8d559ae6712339b8f299fe976e55b162 170 SUPERFAMILY SSF53218 7 167 2.62E-43 T 15-10-2018 IPR036425 MoaB/Mog-like domain superfamily C2I28_12535 524b5a319e265e337b63aea1a6b404d1 377 Pfam PF00296 Luciferase-like monooxygenase 2 323 1.9E-89 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_12535 524b5a319e265e337b63aea1a6b404d1 377 SUPERFAMILY SSF51679 2 347 4.45E-94 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12535 524b5a319e265e337b63aea1a6b404d1 377 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 377 79.722 T 15-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I28_12535 524b5a319e265e337b63aea1a6b404d1 377 Gene3D G3DSA:3.20.20.30 1 360 1.6E-144 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12535 524b5a319e265e337b63aea1a6b404d1 377 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 1.0E-186 T 15-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I28_13185 94d67040e33d2b99e326df1e1bf3c535 516 Gene3D G3DSA:3.20.20.70 58 235 1.1E-8 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_13185 94d67040e33d2b99e326df1e1bf3c535 516 Gene3D G3DSA:2.60.40.10 417 515 7.0E-6 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13185 94d67040e33d2b99e326df1e1bf3c535 516 Pfam PF02638 Glycosyl hydrolase-like 10 35 354 1.0E-110 T 15-10-2018 IPR003790 Glycosyl hydrolase-like 10 C2I28_13185 94d67040e33d2b99e326df1e1bf3c535 516 SUPERFAMILY SSF51445 63 332 1.42E-25 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 15-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 SUPERFAMILY SSF47928 3 105 2.09E-24 T 15-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 Gene3D G3DSA:1.10.520.20 3 105 2.4E-12 T 15-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 175 3.9E-50 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 174 7.3E-49 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 PRINTS PR00125 ATP synthase delta subunit signature 6 25 1.7E-25 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 PRINTS PR00125 ATP synthase delta subunit signature 151 169 1.7E-25 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 PRINTS PR00125 ATP synthase delta subunit signature 136 151 1.7E-25 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.7E-25 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.7E-25 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07330 6df9f197e88814102c1a15500b6ada76 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 19.989 T 15-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_14220 c00c9f715bb1e6711cbb4a792f7c1ef6 362 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 9 360 3.5E-161 T 15-10-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 C2I28_14220 c00c9f715bb1e6711cbb4a792f7c1ef6 362 SUPERFAMILY SSF53474 58 358 2.37E-30 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_14220 c00c9f715bb1e6711cbb4a792f7c1ef6 362 Pfam PF00561 alpha/beta hydrolase fold 72 342 1.5E-17 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_14220 c00c9f715bb1e6711cbb4a792f7c1ef6 362 Gene3D G3DSA:3.40.50.1820 53 361 7.3E-24 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_03365 1d8248deee308dc984bc9eb218a0d1f9 201 Pfam PF02517 CAAX protease self-immunity 101 180 1.3E-8 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_23265 f0f63a477180a809e44b44c27d8dd555 188 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 187 31.088 T 15-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I28_23265 f0f63a477180a809e44b44c27d8dd555 188 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 12 186 2.0E-57 T 15-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I28_23265 f0f63a477180a809e44b44c27d8dd555 188 PIRSF PIRSF001296 5 188 1.9E-70 T 15-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I28_23265 f0f63a477180a809e44b44c27d8dd555 188 Pfam PF02669 K+-transporting ATPase, c chain 12 185 1.8E-67 T 15-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 482 500 7.9E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 481 7.9E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 467 7.9E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 519 7.9E-12 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 SUPERFAMILY SSF103190 33 163 6.28E-39 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Gene3D G3DSA:1.10.287.130 309 371 1.9E-7 T 15-10-2018 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 SUPERFAMILY SSF55890 318 369 1.11E-14 T 15-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 317 370 4.9E-12 T 15-10-2018 IPR039506 SpoOB, alpha-helical domain C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 SMART SM00387 414 522 1.4E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Pfam PF00989 PAS fold 207 307 1.3E-7 T 15-10-2018 IPR013767 PAS fold GO:0006355 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 SUPERFAMILY SSF55785 206 306 2.17E-7 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Pfam PF17203 Single cache domain 3 33 163 1.2E-19 T 15-10-2018 IPR033463 Single cache domain 3 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 SUPERFAMILY SSF55874 392 520 2.49E-28 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Gene3D G3DSA:3.30.450.20 194 308 7.4E-24 T 15-10-2018 C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Gene3D G3DSA:3.30.565.10 372 519 1.7E-28 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 SMART SM00091 207 275 1.6E-4 T 15-10-2018 IPR000014 PAS domain C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 418 521 1.9E-19 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09770 4975ac4e3fe447e7ec515388d7f86bda 528 Gene3D G3DSA:3.30.450.20 27 166 2.4E-43 T 15-10-2018 C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 Pfam PF01174 SNO glutamine amidotransferase family 6 188 3.8E-74 T 15-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 38.043 T 15-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 15-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 184 3.6E-85 T 15-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 PIRSF PIRSF005639 1 191 1.5E-74 T 15-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 Gene3D G3DSA:3.40.50.880 1 194 1.9E-73 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_08090 c4b6224464b769a120aef1a2b0ad6dcc 195 SUPERFAMILY SSF52317 2 189 6.67E-55 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_08400 5f77d1c5c3ca4bacdfcdafbd74c86ad8 88 PIRSF PIRSF038881 1 88 1.2E-33 T 15-10-2018 IPR025490 RNA-binding protein, HP1423 type C2I28_08400 5f77d1c5c3ca4bacdfcdafbd74c86ad8 88 SMART SM00363 1 64 1.1E-8 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08400 5f77d1c5c3ca4bacdfcdafbd74c86ad8 88 Pfam PF01479 S4 domain 1 47 5.9E-10 T 15-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08400 5f77d1c5c3ca4bacdfcdafbd74c86ad8 88 Gene3D G3DSA:3.10.290.10 1 88 4.6E-24 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_08400 5f77d1c5c3ca4bacdfcdafbd74c86ad8 88 SUPERFAMILY SSF55174 1 76 1.11E-19 T 15-10-2018 C2I28_25555 4458090a9ab4144b0c9a037ca9dad08e 261 SUPERFAMILY SSF56300 15 223 1.16E-25 T 15-10-2018 C2I28_25555 4458090a9ab4144b0c9a037ca9dad08e 261 Pfam PF00149 Calcineurin-like phosphoesterase 20 190 6.6E-12 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_25555 4458090a9ab4144b0c9a037ca9dad08e 261 Gene3D G3DSA:3.60.21.10 7 198 3.6E-20 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 Gene3D G3DSA:3.30.450.20 7 147 1.7E-44 T 15-10-2018 C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 SMART SM00091 12 81 6.6E-5 T 15-10-2018 IPR000014 PAS domain C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 SUPERFAMILY SSF52091 148 257 1.31E-10 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 Pfam PF13426 PAS domain 24 127 7.8E-18 T 15-10-2018 IPR000014 PAS domain C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 136 1.4E-14 T 15-10-2018 IPR000014 PAS domain C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 SMART SM00086 87 129 0.001 T 15-10-2018 IPR001610 PAC motif C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 Gene3D G3DSA:3.30.750.24 148 260 2.4E-23 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_23420 535b9d318f9cf335f76f0b1765f9817d 260 SUPERFAMILY SSF55785 21 127 8.38E-22 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_14130 e538d0866e5a5eab8c021181170bc112 388 Pfam PF12698 ABC-2 family transporter protein 18 374 7.7E-35 T 15-10-2018 C2I28_24085 101eaf7e97f2372006468ae2c9132583 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 104 7.2E-24 T 15-10-2018 IPR008407 Branched-chain amino acid transport, AzlD C2I28_25155 c5dab04fe0fb95ce215f6a39451cd694 121 Pfam PF07883 Cupin domain 46 101 2.4E-7 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_25155 c5dab04fe0fb95ce215f6a39451cd694 121 Gene3D G3DSA:2.60.120.10 2 119 2.7E-11 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_25155 c5dab04fe0fb95ce215f6a39451cd694 121 SUPERFAMILY SSF51182 29 104 2.16E-10 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_24440 31d6bab6be54e2c5a524821e9edf1197 86 Pfam PF00741 Gas vesicle protein 11 49 1.4E-15 T 15-10-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 C2I28_24440 31d6bab6be54e2c5a524821e9edf1197 86 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 4 79 25.546 T 15-10-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 C2I28_24440 31d6bab6be54e2c5a524821e9edf1197 86 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 12 26 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24440 31d6bab6be54e2c5a524821e9edf1197 86 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 45 58 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24755 21daed1df6c16c0761ffe093c1c446de 129 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 109 5.8E-15 T 15-10-2018 C2I28_24755 21daed1df6c16c0761ffe093c1c446de 129 Gene3D G3DSA:3.10.180.10 1 126 5.1E-24 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_24755 21daed1df6c16c0761ffe093c1c446de 129 SUPERFAMILY SSF54593 1 127 2.75E-25 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 Gene3D G3DSA:3.30.70.1350 233 314 2.8E-15 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 Pfam PF16916 Dimerisation domain of Zinc Transporter 237 314 6.6E-17 T 15-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 SUPERFAMILY SSF161111 27 233 1.96E-50 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 SUPERFAMILY SSF160240 236 314 4.05E-16 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 30 314 7.8E-74 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 Pfam PF01545 Cation efflux family 34 232 1.7E-44 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_10365 1faeba3e7051f5d75e05897e73b89614 317 Gene3D G3DSA:1.20.1510.10 28 232 6.2E-53 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_03060 4cdd11f875ef013f232026bf74432306 265 SUPERFAMILY SSF52151 3 250 3.4E-57 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_03060 4cdd11f875ef013f232026bf74432306 265 Gene3D G3DSA:3.40.1090.10 1 104 1.3E-24 T 15-10-2018 C2I28_03060 4cdd11f875ef013f232026bf74432306 265 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 15-10-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 C2I28_03060 4cdd11f875ef013f232026bf74432306 265 Pfam PF01734 Patatin-like phospholipase 9 164 2.0E-19 T 15-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 Pfam PF00664 ABC transporter transmembrane region 68 288 3.3E-13 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 Gene3D G3DSA:3.40.50.300 347 597 4.4E-86 T 15-10-2018 C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 SUPERFAMILY SSF90123 16 319 1.7E-27 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 SMART SM00382 381 567 8.7E-18 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 Pfam PF00005 ABC transporter 372 521 3.6E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 SUPERFAMILY SSF52540 346 591 2.45E-83 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18975 0cc61f335f67f8ef750e1e4f3d1d0b86 597 Gene3D G3DSA:1.20.1560.10 6 332 3.4E-22 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_05950 0d494c166cd121784bef7d7533748293 152 Gene3D G3DSA:3.40.50.360 1 146 1.6E-34 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_05950 0d494c166cd121784bef7d7533748293 152 SUPERFAMILY SSF52218 1 146 2.95E-37 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_05950 0d494c166cd121784bef7d7533748293 152 Pfam PF00258 Flavodoxin 7 132 4.2E-27 T 15-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 C2I28_05950 0d494c166cd121784bef7d7533748293 152 TIGRFAM TIGR01753 flav_short: flavodoxin 4 143 1.6E-44 T 15-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 C2I28_01640 e6a3363dbc0b53a583b28568e2341bbe 272 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 4 246 31.091 T 15-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 C2I28_01640 e6a3363dbc0b53a583b28568e2341bbe 272 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 242 7.2E-63 T 15-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_01640 e6a3363dbc0b53a583b28568e2341bbe 272 Pfam PF02096 60Kd inner membrane protein 61 243 1.2E-58 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_01640 e6a3363dbc0b53a583b28568e2341bbe 272 PRINTS PR00701 60kDa inner membrane protein signature 172 194 1.4E-23 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_01640 e6a3363dbc0b53a583b28568e2341bbe 272 PRINTS PR00701 60kDa inner membrane protein signature 209 232 1.4E-23 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_01640 e6a3363dbc0b53a583b28568e2341bbe 272 PRINTS PR00701 60kDa inner membrane protein signature 127 150 1.4E-23 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08865 50cf9f4cc0e50e4fcdc45eccdd2a72dc 235 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 42 226 3.3E-52 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_08865 50cf9f4cc0e50e4fcdc45eccdd2a72dc 235 SMART SM00646 115 226 7.3E-37 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_08865 50cf9f4cc0e50e4fcdc45eccdd2a72dc 235 SUPERFAMILY SSF53187 40 229 1.16E-53 T 15-10-2018 C2I28_08865 50cf9f4cc0e50e4fcdc45eccdd2a72dc 235 Gene3D G3DSA:3.40.630.40 36 234 1.2E-58 T 15-10-2018 C2I28_08865 50cf9f4cc0e50e4fcdc45eccdd2a72dc 235 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 40 228 1.3E-84 T 15-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 SUPERFAMILY SSF51316 169 299 1.15E-31 T 15-10-2018 IPR011057 Mss4-like superfamily C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 2 157 28.59 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 Pfam PF01641 SelR domain 174 285 3.1E-22 T 15-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 Gene3D G3DSA:3.30.1060.10 1 158 1.4E-49 T 15-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 4 150 3.6E-45 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 Gene3D G3DSA:2.170.150.20 168 301 4.9E-29 T 15-10-2018 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 Pfam PF01625 Peptide methionine sulfoxide reductase 5 151 4.6E-45 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_18045 fc531b523768a46f11434efe8d2f86f9 301 SUPERFAMILY SSF55068 3 160 1.7E-53 T 15-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_03715 68de8945fa77d83f76b59b3f29ea47a4 240 Pfam PF00005 ABC transporter 17 165 2.4E-36 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_03715 68de8945fa77d83f76b59b3f29ea47a4 240 SUPERFAMILY SSF52540 1 235 5.2E-79 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03715 68de8945fa77d83f76b59b3f29ea47a4 240 Gene3D G3DSA:3.40.50.300 1 240 1.9E-80 T 15-10-2018 C2I28_03715 68de8945fa77d83f76b59b3f29ea47a4 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_03715 68de8945fa77d83f76b59b3f29ea47a4 240 PIRSF PIRSF039085 1 240 1.0E-112 T 15-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I28_03715 68de8945fa77d83f76b59b3f29ea47a4 240 SMART SM00382 26 213 2.8E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 SUPERFAMILY SSF46894 137 236 2.75E-26 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 Pfam PF00072 Response regulator receiver domain 6 115 3.5E-24 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 Gene3D G3DSA:3.40.50.2300 3 130 6.3E-31 T 15-10-2018 C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 SMART SM00862 159 235 9.9E-21 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 6.0E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 SMART SM00448 4 115 4.7E-35 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 Gene3D G3DSA:1.10.10.10 135 240 3.9E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09680 4b0c7713866e6bc95aede31e5fbe7202 241 SUPERFAMILY SSF52172 3 128 1.71E-34 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_04495 89057bd74ab7767e8ebaff09f1a8a73d 260 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 48 213 7.9E-44 T 15-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 C2I28_04495 89057bd74ab7767e8ebaff09f1a8a73d 260 Pfam PF02666 Phosphatidylserine decarboxylase 59 256 1.1E-51 T 15-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 C2I28_13480 ff6963036b63c964b805d99097116393 268 Gene3D G3DSA:1.10.10.10 3 77 3.0E-14 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13480 ff6963036b63c964b805d99097116393 268 SUPERFAMILY SSF46689 3 77 3.58E-14 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_13480 ff6963036b63c964b805d99097116393 268 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 72 3.1E-10 T 15-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I28_13480 ff6963036b63c964b805d99097116393 268 SUPERFAMILY SSF53697 103 243 4.89E-24 T 15-10-2018 C2I28_13480 ff6963036b63c964b805d99097116393 268 Gene3D G3DSA:3.40.50.10490 92 259 1.0E-29 T 15-10-2018 C2I28_13480 ff6963036b63c964b805d99097116393 268 Pfam PF01380 SIS domain 120 232 1.1E-15 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_03705 a43288bf0402a8114482375128a4d029 174 SUPERFAMILY SSF141523 23 150 9.29E-30 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_03705 a43288bf0402a8114482375128a4d029 174 Pfam PF03734 L,D-transpeptidase catalytic domain 26 149 5.5E-20 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_03705 a43288bf0402a8114482375128a4d029 174 Gene3D G3DSA:2.40.440.10 10 173 3.3E-40 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.0E-11 T 15-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.0E-11 T 15-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.0E-11 T 15-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.974 T 15-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 SUPERFAMILY SSF50249 7 84 2.53E-31 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 15-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 Pfam PF00366 Ribosomal protein S17 12 79 1.8E-32 T 15-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 6.0E-33 T 15-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 Gene3D G3DSA:2.40.50.140 6 86 2.5E-35 T 15-10-2018 C2I28_08730 050c6830d9eb294b2ae506c11a594d0f 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 3.2E-35 T 15-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_00800 1b0d4444763d576a614227b09200658e 516 SUPERFAMILY SSF53850 40 510 1.99E-109 T 15-10-2018 C2I28_00800 1b0d4444763d576a614227b09200658e 516 Gene3D G3DSA:3.10.105.10 283 487 7.8E-30 T 15-10-2018 C2I28_00800 1b0d4444763d576a614227b09200658e 516 Gene3D G3DSA:3.40.190.10 17 282 3.5E-70 T 15-10-2018 C2I28_00800 1b0d4444763d576a614227b09200658e 516 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 91 113 - T 15-10-2018 IPR023765 Solute-binding protein family 5, conserved site C2I28_00800 1b0d4444763d576a614227b09200658e 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 431 9.6E-76 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_00800 1b0d4444763d576a614227b09200658e 516 PIRSF PIRSF002741 3 513 7.4E-89 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_26055 b418e35977b90119a562ab65c838c25b 226 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 4 204 2.5E-41 T 15-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_26055 b418e35977b90119a562ab65c838c25b 226 SUPERFAMILY SSF51569 1 218 3.35E-58 T 15-10-2018 C2I28_26055 b418e35977b90119a562ab65c838c25b 226 Gene3D G3DSA:3.20.20.70 1 225 2.0E-65 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_20445 29f5501545ffa54b7c5480747f66ca2c 263 Gene3D G3DSA:3.30.2040.10 122 234 6.4E-101 T 15-10-2018 C2I28_20445 29f5501545ffa54b7c5480747f66ca2c 263 Gene3D G3DSA:3.40.1640.10 17 250 6.4E-101 T 15-10-2018 C2I28_20445 29f5501545ffa54b7c5480747f66ca2c 263 Hamap MF_01830 Putative hydro-lyase . 8 262 55.176 T 15-10-2018 IPR016938 Uncharacterised protein family UPF0317 C2I28_20445 29f5501545ffa54b7c5480747f66ca2c 263 PIRSF PIRSF029755 1 263 4.2E-129 T 15-10-2018 IPR016938 Uncharacterised protein family UPF0317 C2I28_20445 29f5501545ffa54b7c5480747f66ca2c 263 Pfam PF07286 Protein of unknown function (DUF1445) 112 254 3.6E-69 T 15-10-2018 IPR009906 D-glutamate cyclase C2I28_20445 29f5501545ffa54b7c5480747f66ca2c 263 SUPERFAMILY SSF160920 3 255 4.97E-119 T 15-10-2018 IPR038021 Putative hydro-lyase C2I28_02275 4372ef67d374fb34c51d5e92512748ad 88 SUPERFAMILY SSF50346 1 75 5.89E-11 T 15-10-2018 IPR011033 PRC-barrel-like superfamily C2I28_02275 4372ef67d374fb34c51d5e92512748ad 88 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 75 1.3E-27 T 15-10-2018 IPR014238 Sporulation protein YlmC/YmxH C2I28_02275 4372ef67d374fb34c51d5e92512748ad 88 Gene3D G3DSA:2.30.30.240 1 78 7.1E-9 T 15-10-2018 C2I28_02275 4372ef67d374fb34c51d5e92512748ad 88 Pfam PF05239 PRC-barrel domain 1 76 1.6E-13 T 15-10-2018 IPR027275 PRC-barrel domain C2I28_24665 38b17873cc1a507f2ca1fd281f00488b 297 SUPERFAMILY SSF103481 183 281 3.4E-18 T 15-10-2018 C2I28_24665 38b17873cc1a507f2ca1fd281f00488b 297 Pfam PF00892 EamA-like transporter family 8 136 1.0E-12 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_24665 38b17873cc1a507f2ca1fd281f00488b 297 Pfam PF00892 EamA-like transporter family 145 277 7.5E-25 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_24665 38b17873cc1a507f2ca1fd281f00488b 297 SUPERFAMILY SSF103481 40 139 6.41E-8 T 15-10-2018 C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.3E-21 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 SUPERFAMILY SSF55594 1 81 9.29E-21 T 15-10-2018 IPR035895 HPr-like superfamily C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 Gene3D G3DSA:3.30.1340.10 1 81 6.1E-26 T 15-10-2018 IPR035895 HPr-like superfamily C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 15-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.1E-13 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.1E-13 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.1E-13 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_25280 bde9bed74468e58a43ccc1618b682052 86 Pfam PF00381 PTS HPr component phosphorylation site 4 81 2.8E-21 T 15-10-2018 IPR000032 Phosphocarrier protein HPr-like C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 508 43.172 T 15-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 498 6.0E-39 T 15-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 Gene3D G3DSA:3.20.20.70 1 275 5.4E-111 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 Pfam PF00682 HMGL-like 3 272 4.2E-93 T 15-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 496 1.9E-229 T 15-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 Gene3D G3DSA:3.30.160.270 392 499 2.7E-10 T 15-10-2018 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 Gene3D G3DSA:1.10.238.260 279 391 4.1E-40 T 15-10-2018 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 SMART SM00917 368 499 4.1E-34 T 15-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 15-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 15-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 SUPERFAMILY SSF51569 2 290 2.51E-95 T 15-10-2018 C2I28_05035 2df364a59d2231cf974b6c9b6b1f24ea 511 SUPERFAMILY SSF110921 390 498 4.45E-21 T 15-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 C2I28_04515 6c33d2e0d1905b972f240074dd38d315 76 ProDom PD057834 YRHC TRANSMEMBRANE MEMBRANE 1 59 2.0E-4 T 15-10-2018 IPR025418 YrhC-like protein C2I28_04515 6c33d2e0d1905b972f240074dd38d315 76 Pfam PF14143 YrhC-like protein 4 73 6.0E-19 T 15-10-2018 IPR025418 YrhC-like protein C2I28_03445 767b7005918b412e8a393969dd616db4 190 Hamap MF_01804 Segregation and condensation protein B [scpB]. 4 182 34.266 T 15-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I28_03445 767b7005918b412e8a393969dd616db4 190 Pfam PF04079 Segregation and condensation complex subunit ScpB 8 166 2.0E-55 T 15-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I28_03445 767b7005918b412e8a393969dd616db4 190 SUPERFAMILY SSF46785 2 79 7.86E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_03445 767b7005918b412e8a393969dd616db4 190 Gene3D G3DSA:1.10.10.10 82 178 1.2E-36 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03445 767b7005918b412e8a393969dd616db4 190 Gene3D G3DSA:1.10.10.10 1 81 9.0E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03445 767b7005918b412e8a393969dd616db4 190 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 187 4.2E-54 T 15-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I28_03445 767b7005918b412e8a393969dd616db4 190 SUPERFAMILY SSF46785 83 157 2.99E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_03445 767b7005918b412e8a393969dd616db4 190 PIRSF PIRSF019345 1 189 1.5E-55 T 15-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 C2I28_16650 3a9653e04976e78584f9db04c875069d 342 Gene3D G3DSA:3.40.710.10 10 338 1.0E-44 T 15-10-2018 C2I28_16650 3a9653e04976e78584f9db04c875069d 342 Pfam PF00144 Beta-lactamase 52 321 7.4E-29 T 15-10-2018 IPR001466 Beta-lactamase-related C2I28_16650 3a9653e04976e78584f9db04c875069d 342 SUPERFAMILY SSF56601 9 321 1.22E-39 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_18565 78929c4493bb22f694e7fd1e3706a15a 241 Gene3D G3DSA:3.40.50.880 1 241 2.3E-114 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_18565 78929c4493bb22f694e7fd1e3706a15a 241 PIRSF PIRSF030013 1 240 3.2E-130 T 15-10-2018 IPR009381 Trehalose catabolism protein, ThuA, prokaryote C2I28_18565 78929c4493bb22f694e7fd1e3706a15a 241 Pfam PF06283 Trehalose utilisation 3 218 5.4E-37 T 15-10-2018 IPR029010 ThuA-like domain C2I28_18565 78929c4493bb22f694e7fd1e3706a15a 241 SUPERFAMILY SSF52317 2 235 1.28E-65 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_04230 76719e09f3dbf1659f9569f3bb1ca8b2 234 Pfam PF14181 YqfQ-like protein 68 234 7.6E-56 T 15-10-2018 IPR025571 YqfQ-like protein C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 Pfam PF00795 Carbon-nitrogen hydrolase 231 490 1.7E-31 T 15-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 Gene3D G3DSA:3.40.630.30 4 224 7.6E-63 T 15-10-2018 C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 Gene3D G3DSA:3.60.110.10 226 512 7.2E-59 T 15-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 SUPERFAMILY SSF56317 226 495 3.4E-58 T 15-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 SUPERFAMILY SSF55729 14 143 1.32E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 374 394 - T 15-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site C2I28_10800 a295da285652b863d5aee8ea8fefcde6 512 Pfam PF00583 Acetyltransferase (GNAT) family 24 144 1.5E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 Pfam PF07690 Major Facilitator Superfamily 15 406 8.6E-57 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 Gene3D G3DSA:1.20.1720.10 11 219 2.5E-56 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 4.7E-8 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 4.7E-8 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 4.7E-8 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 4.7E-8 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 355 375 4.7E-8 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 SUPERFAMILY SSF103473 6 498 6.54E-79 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 Gene3D G3DSA:1.20.1250.20 263 498 9.5E-22 T 15-10-2018 C2I28_22665 0b66111afddb13bbf29777b41b7fe359 514 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 490 2.8E-83 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_18125 1472031d07fc49de284dc936a042a157 174 SUPERFAMILY SSF55729 4 147 6.97E-23 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18125 1472031d07fc49de284dc936a042a157 174 Pfam PF00583 Acetyltransferase (GNAT) family 37 136 3.7E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_18125 1472031d07fc49de284dc936a042a157 174 Gene3D G3DSA:3.40.630.30 2 156 6.9E-23 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 Gene3D G3DSA:3.60.20.40 347 517 1.3E-54 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 230 246 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 68 93 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 259 278 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 121 139 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 139 158 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 347 365 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 398 413 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 422 439 3.2E-53 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 Gene3D G3DSA:1.10.246.230 246 346 1.1E-29 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 Pfam PF01019 Gamma-glutamyltranspeptidase 61 514 2.1E-103 T 15-10-2018 C2I28_13155 96e470e4ca60476f8e17b0ff5c94463a 520 SUPERFAMILY SSF56235 45 516 2.12E-123 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 Gene3D G3DSA:3.40.50.720 2 259 1.5E-77 T 15-10-2018 C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 3.6E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.6E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.6E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.6E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.6E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.6E-34 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 256 8.6E-60 T 15-10-2018 C2I28_21675 8783f42e161fde0ca8d02f7dae98fa56 260 SUPERFAMILY SSF51735 6 259 1.33E-74 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 Pfam PF01546 Peptidase family M20/M25/M40 86 463 1.5E-31 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 116 154 - T 15-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 SUPERFAMILY SSF53187 4 466 3.55E-63 T 15-10-2018 C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 SUPERFAMILY SSF55031 186 379 1.64E-54 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 Gene3D G3DSA:3.30.70.360 205 292 4.6E-172 T 15-10-2018 C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 Gene3D G3DSA:3.40.630.10 16 465 4.6E-172 T 15-10-2018 C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 Gene3D G3DSA:3.30.70.360 186 381 4.6E-172 T 15-10-2018 C2I28_05760 f41ec7ecbf5edd6b50d38e464c8c1f3a 467 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 16 462 2.0E-174 T 15-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 49.643 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 318 4.1E-160 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 8.4E-67 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 4.3E-47 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 4.3E-47 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 4.3E-47 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 4.3E-47 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 4.3E-47 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 4.3E-47 T 15-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 SUPERFAMILY SSF52096 6 315 3.83E-101 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_05430 123e48efbb96a8a351bfafc8758a02dd 325 Gene3D G3DSA:3.90.226.10 2 317 2.7E-124 T 15-10-2018 C2I28_00055 6ea27062a031ba2720b9d403f45a89b8 75 SMART SM00530 12 67 2.7E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_00055 6ea27062a031ba2720b9d403f45a89b8 75 Gene3D G3DSA:1.10.260.40 8 72 8.6E-24 T 15-10-2018 C2I28_00055 6ea27062a031ba2720b9d403f45a89b8 75 SUPERFAMILY SSF47413 10 69 1.49E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_00055 6ea27062a031ba2720b9d403f45a89b8 75 Pfam PF01381 Helix-turn-helix 15 66 4.8E-12 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26165 6ea27062a031ba2720b9d403f45a89b8 75 SMART SM00530 12 67 2.7E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_26165 6ea27062a031ba2720b9d403f45a89b8 75 Gene3D G3DSA:1.10.260.40 8 72 8.6E-24 T 15-10-2018 C2I28_26165 6ea27062a031ba2720b9d403f45a89b8 75 SUPERFAMILY SSF47413 10 69 1.49E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_26165 6ea27062a031ba2720b9d403f45a89b8 75 Pfam PF01381 Helix-turn-helix 15 66 4.8E-12 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 290 1.8E-66 T 15-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 Gene3D G3DSA:1.10.1040.10 168 293 3.5E-42 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 Gene3D G3DSA:3.40.50.720 2 167 1.4E-50 T 15-10-2018 C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 148 1.8E-28 T 15-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 SUPERFAMILY SSF51735 3 153 1.28E-21 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 288 1.7E-27 T 15-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain C2I28_03005 8152c06607875daa31ac401ab9407fe1 293 SUPERFAMILY SSF48179 168 288 5.1E-25 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_16470 3c6752145d44911dcbb01070a59cb324 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 2.8E-22 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_16470 3c6752145d44911dcbb01070a59cb324 102 SUPERFAMILY SSF52794 1 101 6.02E-35 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_16470 3c6752145d44911dcbb01070a59cb324 102 Gene3D G3DSA:3.40.50.2300 2 102 2.3E-34 T 15-10-2018 C2I28_24110 54ad91a2101086acc06ac48371eb12dc 159 SUPERFAMILY SSF46785 12 134 1.73E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24110 54ad91a2101086acc06ac48371eb12dc 159 Pfam PF02082 Transcriptional regulator 3 83 6.9E-15 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_24110 54ad91a2101086acc06ac48371eb12dc 159 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 134 1.5E-22 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_24110 54ad91a2101086acc06ac48371eb12dc 159 Gene3D G3DSA:1.10.10.10 1 148 3.5E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 SUPERFAMILY SSF47741 81 155 5.23E-28 T 15-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 Gene3D G3DSA:1.10.150.120 83 158 6.4E-26 T 15-10-2018 C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 Pfam PF01799 [2Fe-2S] binding domain 81 150 9.6E-26 T 15-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 47 55 - T 15-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 75 6.2E-6 T 15-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 Gene3D G3DSA:3.10.20.30 7 82 1.6E-28 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_20945 3085930f7326d61070189c7bd060ff2e 159 SUPERFAMILY SSF54292 8 86 2.62E-22 T 15-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I28_01210 dd47d6b6d987620d1f1390e5c56025c7 350 Gene3D G3DSA:2.102.10.10 30 160 3.9E-34 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_01210 dd47d6b6d987620d1f1390e5c56025c7 350 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 73 95 - T 15-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 C2I28_01210 dd47d6b6d987620d1f1390e5c56025c7 350 SUPERFAMILY SSF55961 141 345 9.16E-28 T 15-10-2018 C2I28_01210 dd47d6b6d987620d1f1390e5c56025c7 350 Pfam PF00355 Rieske [2Fe-2S] domain 34 113 9.9E-19 T 15-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I28_01210 dd47d6b6d987620d1f1390e5c56025c7 350 SUPERFAMILY SSF50022 15 139 1.09E-34 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_01210 dd47d6b6d987620d1f1390e5c56025c7 350 Gene3D G3DSA:3.30.530.90 172 346 2.7E-10 T 15-10-2018 C2I28_14745 db412c1e9563c03d3e8e52bb6a13bc58 69 Gene3D G3DSA:3.10.20.730 1 58 1.7E-24 T 15-10-2018 C2I28_14745 db412c1e9563c03d3e8e52bb6a13bc58 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 9.6E-27 T 15-10-2018 IPR009907 Protein of unknown function DUF1447 C2I28_14745 db412c1e9563c03d3e8e52bb6a13bc58 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 4.0E-18 T 15-10-2018 IPR009907 Protein of unknown function DUF1447 C2I28_14745 db412c1e9563c03d3e8e52bb6a13bc58 69 Hamap MF_01553 UPF0356 protein . 1 69 20.204 T 15-10-2018 IPR009907 Protein of unknown function DUF1447 C2I28_19895 d95ff6c56742b5e033aaa5e243e27c9f 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 68 1.5E-21 T 15-10-2018 C2I28_19895 d95ff6c56742b5e033aaa5e243e27c9f 82 Gene3D G3DSA:3.30.70.20 2 82 1.9E-34 T 15-10-2018 C2I28_19895 d95ff6c56742b5e033aaa5e243e27c9f 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 1.6E-7 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_19895 d95ff6c56742b5e033aaa5e243e27c9f 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 1.6E-7 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_19895 d95ff6c56742b5e033aaa5e243e27c9f 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 1.6E-7 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_19895 d95ff6c56742b5e033aaa5e243e27c9f 82 SUPERFAMILY SSF54862 4 72 6.74E-13 T 15-10-2018 C2I28_01595 af7e1ea9b4a1a4a54bf6ece298282da2 251 SUPERFAMILY SSF53474 76 246 1.0E-18 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_01595 af7e1ea9b4a1a4a54bf6ece298282da2 251 Gene3D G3DSA:3.40.50.1820 33 250 6.3E-20 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_01595 af7e1ea9b4a1a4a54bf6ece298282da2 251 Pfam PF12695 Alpha/beta hydrolase family 68 230 2.8E-58 T 15-10-2018 IPR029059 Alpha/beta hydrolase fold-5 C2I28_10775 8c1ac13fd7d249183291101a46fcc84a 130 Pfam PF17326 Family of unknown function (DUF5365) 1 115 9.1E-36 T 15-10-2018 IPR020355 Uncharacterised protein family YhcU C2I28_10775 8c1ac13fd7d249183291101a46fcc84a 130 ProDom PD081567 YHCU 1 110 2.0E-10 T 15-10-2018 IPR020355 Uncharacterised protein family YhcU C2I28_22385 d097950577971b15935207e5265b92a2 184 Pfam PF00583 Acetyltransferase (GNAT) family 44 165 1.1E-15 T 15-10-2018 IPR000182 GNAT domain C2I28_22385 d097950577971b15935207e5265b92a2 184 SUPERFAMILY SSF55729 3 182 2.62E-27 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22385 d097950577971b15935207e5265b92a2 184 Gene3D G3DSA:3.40.630.30 2 184 2.4E-42 T 15-10-2018 C2I28_00015 bf716aff884c1be6901e4946b8758e72 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 81 3.3E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_00015 bf716aff884c1be6901e4946b8758e72 206 Gene3D G3DSA:1.10.357.10 25 205 9.6E-18 T 15-10-2018 C2I28_00015 bf716aff884c1be6901e4946b8758e72 206 SUPERFAMILY SSF46689 29 98 1.18E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_26125 bf716aff884c1be6901e4946b8758e72 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 81 3.3E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_26125 bf716aff884c1be6901e4946b8758e72 206 Gene3D G3DSA:1.10.357.10 25 205 9.6E-18 T 15-10-2018 C2I28_26125 bf716aff884c1be6901e4946b8758e72 206 SUPERFAMILY SSF46689 29 98 1.18E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_18645 b4bd67e440f806c95c72351d00ba5fe4 150 Pfam PF01381 Helix-turn-helix 14 48 1.3E-7 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_18645 b4bd67e440f806c95c72351d00ba5fe4 150 SMART SM00530 13 67 7.9E-7 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_18645 b4bd67e440f806c95c72351d00ba5fe4 150 Gene3D G3DSA:1.10.260.40 2 69 3.2E-10 T 15-10-2018 C2I28_18645 b4bd67e440f806c95c72351d00ba5fe4 150 SUPERFAMILY SSF47413 7 61 4.56E-11 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 Gene3D G3DSA:3.40.190.290 92 292 3.0E-43 T 15-10-2018 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 SUPERFAMILY SSF53850 97 291 9.46E-34 T 15-10-2018 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 Pfam PF03466 LysR substrate binding domain 91 285 1.4E-35 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.3E-18 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 Gene3D G3DSA:1.10.10.10 1 84 7.8E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.8E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.8E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.8E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_11745 51b7012a2166d345be79a4cc0395c897 298 SUPERFAMILY SSF46785 2 87 1.85E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 Gene3D G3DSA:3.40.50.300 291 645 3.2E-130 T 15-10-2018 C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 Pfam PF13361 UvrD-like helicase C-terminal domain 288 624 1.4E-72 T 15-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 16 746 0.0 T 15-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 SUPERFAMILY SSF52540 11 654 2.66E-186 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 Gene3D G3DSA:1.10.486.10 394 559 3.2E-130 T 15-10-2018 C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 Gene3D G3DSA:1.10.10.160 124 198 2.2E-109 T 15-10-2018 IPR013986 DExx box DNA helicase domain superfamily C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 Gene3D G3DSA:3.40.50.300 20 285 2.2E-109 T 15-10-2018 C2I28_09510 e9777b0e387344e7a001dcd6c91ceecc 749 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 283 1.2E-84 T 15-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 C2I28_15340 04d0695abe06f1908da08ab8e41acb1d 133 SUPERFAMILY SSF53098 1 123 1.39E-31 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_15340 04d0695abe06f1908da08ab8e41acb1d 133 Pfam PF13456 Reverse transcriptase-like 8 125 1.5E-19 T 15-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 C2I28_15340 04d0695abe06f1908da08ab8e41acb1d 133 Gene3D G3DSA:3.30.420.10 2 132 2.2E-32 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_25395 de7e2b399c1d26c6b87afebf6c1591cd 112 Pfam PF11181 Heat induced stress protein YflT 4 103 1.9E-21 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 SUPERFAMILY SSF56784 314 575 3.93E-41 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 Pfam PF00122 E1-E2 ATPase 122 295 8.6E-35 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 320 326 - T 15-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 24 691 39.876 T 15-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 Gene3D G3DSA:3.40.1110.10 331 458 1.8E-45 T 15-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 474 484 2.6E-26 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 318 332 2.6E-26 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 2.6E-26 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 463 2.6E-26 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 550 562 2.6E-26 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 546 2.6E-26 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 SUPERFAMILY SSF81653 121 220 4.05E-23 T 15-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 344 1.2E-32 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 384 612 7.6E-48 T 15-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 Pfam PF00702 haloacid dehalogenase-like hydrolase 314 541 9.0E-35 T 15-10-2018 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 SUPERFAMILY SSF81665 47 653 3.4E-10 T 15-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 27 687 0.0 T 15-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 C2I28_23270 a9bba3f29388c0882e6b5c57833aeab3 691 Gene3D G3DSA:2.70.150.20 120 225 3.7E-29 T 15-10-2018 C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 408 1.0E-114 T 15-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 Gene3D G3DSA:3.40.630.10 26 417 3.1E-140 T 15-10-2018 C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 Gene3D G3DSA:3.30.70.360 203 329 3.1E-140 T 15-10-2018 C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 SUPERFAMILY SSF53187 5 417 3.43E-60 T 15-10-2018 C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 Pfam PF07687 Peptidase dimerisation domain 201 307 3.4E-16 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 Pfam PF01546 Peptidase family M20/M25/M40 96 413 2.4E-35 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_01765 3dba539fb9b8c36b04ef45cf3087c358 421 SUPERFAMILY SSF55031 203 307 6.58E-14 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 322 345 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 349 370 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 455 478 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 430 453 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 PRINTS PR00702 Acriflavin resistance protein family signature 377 401 5.4E-38 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:3.30.70.1440 636 828 7.4E-235 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:3.30.70.1320 133 318 7.4E-235 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:3.30.70.1430 538 635 7.4E-235 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:1.20.1640.10 495 985 7.4E-235 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:3.30.2090.10 177 262 7.4E-235 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 SUPERFAMILY SSF82693 43 132 9.16E-18 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:3.30.2090.10 684 765 7.4E-235 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 SUPERFAMILY SSF82714 183 258 4.19E-7 T 15-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 SUPERFAMILY SSF82866 765 992 1.83E-42 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Pfam PF00873 AcrB/AcrD/AcrF family 6 989 4.7E-181 T 15-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 SUPERFAMILY SSF82866 285 480 1.57E-38 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:1.20.1640.10 11 494 7.4E-235 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 Gene3D G3DSA:3.30.70.1430 41 773 7.4E-235 T 15-10-2018 C2I28_13505 7b0146a97662c966c70a1efab880ea35 1009 SUPERFAMILY SSF82693 150 303 1.2E-6 T 15-10-2018 C2I28_20850 08147141f94bb5dc3632cfad14688628 137 SUPERFAMILY SSF51735 10 135 7.35E-40 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_20850 08147141f94bb5dc3632cfad14688628 137 SMART SM00881 14 107 3.8E-16 T 15-10-2018 IPR003781 CoA-binding GO:0048037 C2I28_20850 08147141f94bb5dc3632cfad14688628 137 Gene3D G3DSA:3.40.50.720 2 137 9.1E-38 T 15-10-2018 C2I28_20850 08147141f94bb5dc3632cfad14688628 137 Pfam PF13380 CoA binding domain 19 133 2.0E-37 T 15-10-2018 IPR003781 CoA-binding GO:0048037 C2I28_18450 56e070553075d8d783612e276d458607 454 SUPERFAMILY SSF158472 190 238 2.62E-5 T 15-10-2018 C2I28_18450 56e070553075d8d783612e276d458607 454 Pfam PF00672 HAMP domain 190 237 8.8E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_18450 56e070553075d8d783612e276d458607 454 SMART SM00387 360 454 2.5E-9 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18450 56e070553075d8d783612e276d458607 454 Gene3D G3DSA:1.10.287.130 187 309 5.1E-17 T 15-10-2018 C2I28_18450 56e070553075d8d783612e276d458607 454 SUPERFAMILY SSF55874 319 444 7.33E-19 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18450 56e070553075d8d783612e276d458607 454 SMART SM00304 189 241 1.8E-5 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_18450 56e070553075d8d783612e276d458607 454 Gene3D G3DSA:3.30.565.10 322 454 3.3E-18 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_18450 56e070553075d8d783612e276d458607 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 450 3.8E-7 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_18450 56e070553075d8d783612e276d458607 454 SUPERFAMILY SSF47384 233 310 1.1E-10 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_18450 56e070553075d8d783612e276d458607 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 307 3.3E-6 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_18450 56e070553075d8d783612e276d458607 454 SMART SM00388 249 314 1.1E-4 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_21295 23a324dadf48fbe2fd13231e907b462e 692 Gene3D G3DSA:1.10.10.2840 562 690 4.7E-19 T 15-10-2018 C2I28_21295 23a324dadf48fbe2fd13231e907b462e 692 SMART SM00065 114 293 3.9E-9 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_21295 23a324dadf48fbe2fd13231e907b462e 692 Pfam PF13556 PucR C-terminal helix-turn-helix domain 630 685 4.1E-19 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_21295 23a324dadf48fbe2fd13231e907b462e 692 Pfam PF13185 GAF domain 136 283 9.4E-13 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_21295 23a324dadf48fbe2fd13231e907b462e 692 SUPERFAMILY SSF55781 118 299 1.26E-21 T 15-10-2018 C2I28_21295 23a324dadf48fbe2fd13231e907b462e 692 Gene3D G3DSA:3.30.450.40 104 301 1.2E-25 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Pfam PF13932 GidA associated domain 401 615 8.4E-81 T 15-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 15-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Gene3D G3DSA:1.10.10.1800 459 549 6.3E-27 T 15-10-2018 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Gene3D G3DSA:3.50.50.60 296 458 5.8E-56 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Gene3D G3DSA:3.50.50.60 2 221 2.1E-84 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_07985 59e7517b2183489ec08d9869812956ce 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.4E-6 T 15-10-2018 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 3.4E-6 T 15-10-2018 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.409 T 15-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 8.9E-297 T 15-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 SMART SM01228 545 616 3.1E-42 T 15-10-2018 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 15-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Pfam PF01134 Glucose inhibited division protein A 9 398 3.9E-172 T 15-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 C2I28_07985 59e7517b2183489ec08d9869812956ce 629 SUPERFAMILY SSF51905 7 261 6.8E-46 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_07985 59e7517b2183489ec08d9869812956ce 629 Gene3D G3DSA:1.10.150.570 568 620 4.4E-24 T 15-10-2018 C2I28_00370 7dce114fbc6cb7a72c318c0623b2f128 389 Gene3D G3DSA:1.20.1250.20 1 193 8.9E-20 T 15-10-2018 C2I28_00370 7dce114fbc6cb7a72c318c0623b2f128 389 Pfam PF07690 Major Facilitator Superfamily 13 289 6.1E-32 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_00370 7dce114fbc6cb7a72c318c0623b2f128 389 Gene3D G3DSA:1.20.1250.20 198 381 1.3E-18 T 15-10-2018 C2I28_00370 7dce114fbc6cb7a72c318c0623b2f128 389 SUPERFAMILY SSF103473 3 381 7.98E-52 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_14625 5670a56d49a6e12a690df7e6e14634cd 155 Pfam PF14177 YkyB-like protein 14 151 1.0E-62 T 15-10-2018 IPR025552 YkyB-like protein C2I28_06560 a4ffcde27673c084e1649f1239cfebfd 99 Gene3D G3DSA:3.40.30.10 3 99 4.1E-11 T 15-10-2018 C2I28_06560 a4ffcde27673c084e1649f1239cfebfd 99 SUPERFAMILY SSF52833 6 98 1.22E-14 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_06560 a4ffcde27673c084e1649f1239cfebfd 99 Pfam PF00085 Thioredoxin 5 86 9.0E-7 T 15-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I28_25825 507ca4dde22668bb0b93a8149781bad7 167 PIRSF PIRSF032285 1 167 3.2E-63 T 15-10-2018 IPR011235 MepB-like C2I28_25825 507ca4dde22668bb0b93a8149781bad7 167 Pfam PF08877 MepB protein 28 150 3.6E-48 T 15-10-2018 IPR011235 MepB-like C2I28_25825 507ca4dde22668bb0b93a8149781bad7 167 Gene3D G3DSA:3.40.1350.140 3 162 5.1E-55 T 15-10-2018 IPR038231 MepB-like superfamily C2I28_23700 821389ee4b0a83743cf6ddd6ffd7a8ae 97 Pfam PF12823 Domain of unknown function (DUF3817) 8 94 9.1E-25 T 15-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane C2I28_23700 821389ee4b0a83743cf6ddd6ffd7a8ae 97 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 10 93 9.1E-31 T 15-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane C2I28_19305 83470ab3f7c2a4bbca3022862df7232e 395 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 175 203 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_19305 83470ab3f7c2a4bbca3022862df7232e 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 359 1.2E-90 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_19305 83470ab3f7c2a4bbca3022862df7232e 395 SUPERFAMILY SSF56796 4 383 6.02E-91 T 15-10-2018 C2I28_19305 83470ab3f7c2a4bbca3022862df7232e 395 Gene3D G3DSA:1.20.1090.10 188 387 2.0E-45 T 15-10-2018 C2I28_19305 83470ab3f7c2a4bbca3022862df7232e 395 Gene3D G3DSA:3.40.50.1970 1 186 1.9E-46 T 15-10-2018 C2I28_13740 f21b3e6fa5958e73870cd8d3023a583a 293 Gene3D G3DSA:3.90.550.10 1 292 9.9E-98 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13740 f21b3e6fa5958e73870cd8d3023a583a 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 9.0E-121 T 15-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I28_13740 f21b3e6fa5958e73870cd8d3023a583a 293 SUPERFAMILY SSF53448 4 275 3.13E-72 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13740 f21b3e6fa5958e73870cd8d3023a583a 293 Pfam PF00483 Nucleotidyl transferase 6 263 2.2E-37 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Gene3D G3DSA:3.40.50.300 1 150 1.5E-42 T 15-10-2018 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 416 3.6E-65 T 15-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Pfam PF16193 AAA C-terminal domain 174 252 1.9E-28 T 15-10-2018 IPR032423 AAA C-terminal domain C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Gene3D G3DSA:1.10.8.60 151 225 3.9E-20 T 15-10-2018 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 9 128 5.7E-17 T 15-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 SMART SM00382 39 151 8.2E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_04650 e66c08087f8d4feb365822da658b394a 425 SUPERFAMILY SSF48019 238 420 4.36E-72 T 15-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Gene3D G3DSA:1.10.3710.10 331 425 2.8E-26 T 15-10-2018 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 Gene3D G3DSA:1.20.272.10 228 330 2.0E-41 T 15-10-2018 C2I28_04650 e66c08087f8d4feb365822da658b394a 425 SUPERFAMILY SSF52540 4 225 9.24E-43 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07860 46bcf32968868138f81c9cf6457dff7c 259 Pfam PF09648 YycH protein 40 249 9.3E-57 T 15-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 C2I28_07860 46bcf32968868138f81c9cf6457dff7c 259 Gene3D G3DSA:3.30.310.160 70 181 4.8E-65 T 15-10-2018 C2I28_07860 46bcf32968868138f81c9cf6457dff7c 259 Gene3D G3DSA:3.10.450.660 49 253 4.8E-65 T 15-10-2018 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 8.0E-28 T 15-10-2018 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 Gene3D G3DSA:3.30.70.1150 84 165 1.9E-27 T 15-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 SUPERFAMILY SSF55021 2 77 1.57E-19 T 15-10-2018 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.3E-27 T 15-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 1.3E-62 T 15-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 Gene3D G3DSA:3.30.70.260 1 80 6.7E-30 T 15-10-2018 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 SUPERFAMILY SSF55021 80 160 1.05E-24 T 15-10-2018 C2I28_05045 22b5e582524183677d1581b3adbe2d2c 170 Pfam PF01842 ACT domain 5 68 4.8E-13 T 15-10-2018 IPR002912 ACT domain C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 Gene3D G3DSA:3.40.50.300 3 331 3.2E-100 T 15-10-2018 C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 2.1E-28 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 4.5E-21 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 Pfam PF00005 ABC transporter 25 183 6.6E-29 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 SMART SM00382 34 241 1.7E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17080 0e7bb150d43a568b0bfac0112f715efe 332 SUPERFAMILY SSF52540 5 254 1.18E-68 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 447 3.3E-146 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 PRINTS PR00175 Sodium/alanine symporter signature 295 313 2.9E-59 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 PRINTS PR00175 Sodium/alanine symporter signature 353 375 2.9E-59 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 PRINTS PR00175 Sodium/alanine symporter signature 204 223 2.9E-59 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 PRINTS PR00175 Sodium/alanine symporter signature 86 108 2.9E-59 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 PRINTS PR00175 Sodium/alanine symporter signature 176 194 2.9E-59 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 PRINTS PR00175 Sodium/alanine symporter signature 416 436 2.9E-59 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_09745 c0b2fa455bdbb3592a388106f56e46bd 484 Pfam PF01235 Sodium:alanine symporter family 49 459 1.2E-158 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_15965 705f3e2d25f5000dd98d3dba91c6ec29 283 PIRSF PIRSF002854 1 268 3.7E-91 T 15-10-2018 IPR004872 Lipoprotein NlpA family C2I28_15965 705f3e2d25f5000dd98d3dba91c6ec29 283 Pfam PF03180 NLPA lipoprotein 33 267 6.4E-84 T 15-10-2018 IPR004872 Lipoprotein NlpA family C2I28_15965 705f3e2d25f5000dd98d3dba91c6ec29 283 Gene3D G3DSA:3.40.190.10 110 219 1.6E-89 T 15-10-2018 C2I28_15965 705f3e2d25f5000dd98d3dba91c6ec29 283 SUPERFAMILY SSF53850 32 279 4.86E-77 T 15-10-2018 C2I28_15965 705f3e2d25f5000dd98d3dba91c6ec29 283 Gene3D G3DSA:3.40.190.10 34 258 1.6E-89 T 15-10-2018 C2I28_23215 ff303688860ada6b0875924ad90fcf1b 138 Pfam PF03994 Domain of Unknown Function (DUF350) 81 136 2.0E-13 T 15-10-2018 IPR007140 Protein of unknown function DUF350 C2I28_23215 ff303688860ada6b0875924ad90fcf1b 138 Pfam PF03994 Domain of Unknown Function (DUF350) 18 65 8.0E-12 T 15-10-2018 IPR007140 Protein of unknown function DUF350 C2I28_17605 561d90d54f7ec8dc767d6b7b872f86a0 303 Pfam PF03547 Membrane transport protein 12 143 3.4E-10 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_26525 30bec9056c8a96b66adff8fea4b52283 153 SUPERFAMILY SSF55961 1 147 5.79E-17 T 15-10-2018 C2I28_26525 30bec9056c8a96b66adff8fea4b52283 153 Gene3D G3DSA:3.30.530.20 2 150 1.0E-28 T 15-10-2018 IPR023393 START-like domain superfamily C2I28_26525 30bec9056c8a96b66adff8fea4b52283 153 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 13 134 1.5E-5 T 15-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 C2I28_16605 b6e688702771291c735282b47e56e11d 229 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 3 108 4.7E-15 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_16605 b6e688702771291c735282b47e56e11d 229 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 137 226 2.0E-5 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 Pfam PF00355 Rieske [2Fe-2S] domain 427 501 8.0E-14 T 15-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 PRINTS PR00162 Rieske 2Fe-2S subunit signature 488 500 8.4E-8 T 15-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 PRINTS PR00162 Rieske 2Fe-2S subunit signature 455 466 8.4E-8 T 15-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 PRINTS PR00162 Rieske 2Fe-2S subunit signature 476 488 8.4E-8 T 15-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 Gene3D G3DSA:2.102.10.10 405 513 2.1E-26 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 Gene3D G3DSA:3.50.50.60 31 377 3.8E-44 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 Pfam PF01266 FAD dependent oxidoreductase 31 374 1.9E-40 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 SUPERFAMILY SSF50022 424 506 6.42E-25 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 SUPERFAMILY SSF51905 30 387 6.09E-33 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_23115 f32a4661dee34d53c4740fb1572becf7 514 Gene3D G3DSA:3.30.9.10 124 335 3.8E-44 T 15-10-2018 C2I28_03340 9944727b30e3fa22d048c825d00b8107 200 PIRSF PIRSF029008 1 200 1.9E-51 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_03340 9944727b30e3fa22d048c825d00b8107 200 Gene3D G3DSA:3.30.70.1950 108 200 2.8E-26 T 15-10-2018 IPR038471 MecA, C-terminal domain superfamily C2I28_03340 9944727b30e3fa22d048c825d00b8107 200 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 103 2.4E-24 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_03340 9944727b30e3fa22d048c825d00b8107 200 Pfam PF05389 Negative regulator of genetic competence (MecA) 108 193 7.7E-18 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_03340 9944727b30e3fa22d048c825d00b8107 200 Hamap MF_01124 Adapter protein MecA [mecA]. 1 199 22.387 T 15-10-2018 IPR008681 Negative regulator of genetic competence, MecA C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 7 343 47.594 T 15-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 341 1.6E-127 T 15-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 23 32 - T 15-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 141 157 - T 15-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 Gene3D G3DSA:3.20.20.210 1 347 1.9E-148 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 342 1.2E-123 T 15-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 C2I28_11155 f46dc51bb7134c068995cd53946004a4 347 SUPERFAMILY SSF51726 5 344 4.06E-103 T 15-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 C2I28_18960 3f41b2df4d9386e57f4901a09fd0a20e 101 Gene3D G3DSA:1.10.10.1150 20 95 3.1E-5 T 15-10-2018 C2I28_18960 3f41b2df4d9386e57f4901a09fd0a20e 101 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 27 93 1.2E-15 T 15-10-2018 IPR008792 Coenzyme PQQ synthesis D C2I28_12975 23737a2a9994e58a3f3ecaf04275d6fc 395 Pfam PF01566 Natural resistance-associated macrophage protein 43 363 2.1E-24 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_14310 2be18101b82b37cc95838b5461a86599 212 SUPERFAMILY SSF53639 6 208 1.26E-38 T 15-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I28_14310 2be18101b82b37cc95838b5461a86599 212 SMART SM01007 10 198 1.1E-30 T 15-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I28_14310 2be18101b82b37cc95838b5461a86599 212 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 206 98.087 T 15-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I28_14310 2be18101b82b37cc95838b5461a86599 212 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 12 202 4.1E-63 T 15-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I28_14310 2be18101b82b37cc95838b5461a86599 212 Gene3D G3DSA:3.40.225.10 5 209 7.9E-43 T 15-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily C2I28_14310 2be18101b82b37cc95838b5461a86599 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 195 5.4E-34 T 15-10-2018 IPR001303 Class II aldolase/adducin N-terminal C2I28_12965 ed6b04a03e010feb27cb7c7c9074d4df 332 SMART SM00797 24 320 1.5E-132 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_12965 ed6b04a03e010feb27cb7c7c9074d4df 332 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 303 6.8E-94 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_12965 ed6b04a03e010feb27cb7c7c9074d4df 332 SUPERFAMILY SSF50891 196 310 1.67E-12 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_12965 ed6b04a03e010feb27cb7c7c9074d4df 332 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 329 4.7E-100 T 15-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B C2I28_12965 ed6b04a03e010feb27cb7c7c9074d4df 332 Gene3D G3DSA:2.40.100.10 193 331 5.3E-54 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_02930 4b66e3f1de0839991929bdff8d779287 307 PIRSF PIRSF018571 1 300 4.4E-90 T 15-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 C2I28_02930 4b66e3f1de0839991929bdff8d779287 307 Pfam PF03419 Sporulation factor SpoIIGA 3 297 1.2E-85 T 15-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 C2I28_02930 4b66e3f1de0839991929bdff8d779287 307 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 3 298 3.3E-97 T 15-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 2.0E-99 T 15-10-2018 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 Gene3D G3DSA:1.10.3370.10 1 425 7.4E-160 T 15-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 SUPERFAMILY SSF103491 1 420 2.09E-129 T 15-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 15-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 8.1E-149 T 15-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 29.21 T 15-10-2018 IPR026593 Protein translocase subunit SecY C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 Pfam PF00344 SecY translocase 68 413 1.6E-114 T 15-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 15-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08785 0b2061461774e30e1c153f9e3ae9dabf 430 PIRSF PIRSF004557 1 430 1.3E-127 T 15-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 Gene3D G3DSA:3.40.50.720 1 188 1.8E-71 T 15-10-2018 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 SUPERFAMILY SSF48179 185 283 1.28E-34 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 15-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 PIRSF PIRSF000105 1 284 4.6E-95 T 15-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 5.5E-66 T 15-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 Gene3D G3DSA:1.10.1040.10 193 278 1.1E-36 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 9.3E-36 T 15-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_07495 b9a3f9be123905cf62e41f0191d625a9 284 SUPERFAMILY SSF51735 2 185 4.16E-59 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 67 5.8E-23 T 15-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 SUPERFAMILY SSF81333 3 68 1.57E-19 T 15-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.85 T 15-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 2.8E-19 T 15-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 2.8E-19 T 15-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 2.8E-19 T 15-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 15-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 Gene3D G3DSA:1.20.20.10 1 70 3.3E-27 T 15-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07340 26099481824b0ba870be159b0b5a16c5 70 Pfam PF00137 ATP synthase subunit C 4 66 2.1E-14 T 15-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 C2I28_21755 371d08fb8ec7502743ad329b4550046d 328 Pfam PF14267 Domain of unknown function (DUF4357) 264 314 6.6E-14 T 15-10-2018 IPR025579 Domain of unknown function DUF4357 C2I28_18115 d6423946bc21a58a0a3579e2403d34ab 341 SUPERFAMILY SSF51679 2 324 2.0E-63 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_18115 d6423946bc21a58a0a3579e2403d34ab 341 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 325 5.0E-112 T 15-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 C2I28_18115 d6423946bc21a58a0a3579e2403d34ab 341 Pfam PF00296 Luciferase-like monooxygenase 16 297 3.4E-35 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_18115 d6423946bc21a58a0a3579e2403d34ab 341 Gene3D G3DSA:3.20.20.30 1 328 1.8E-91 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_05945 a002f6ceafd421e75659b4834d77ffbc 345 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 332 1.1E-37 T 15-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.681 T 15-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 Gene3D G3DSA:3.30.420.40 1 88 9.6E-35 T 15-10-2018 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 1.7E-86 T 15-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 SUPERFAMILY SSF53067 124 252 9.39E-41 T 15-10-2018 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 SUPERFAMILY SSF53067 1 122 1.09E-38 T 15-10-2018 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 Pfam PF03309 Type III pantothenate kinase 3 205 8.9E-74 T 15-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 C2I28_08465 4f43eac5c9b67c8db3d0fb2170e960b1 255 Gene3D G3DSA:3.30.420.40 89 255 1.7E-62 T 15-10-2018 C2I28_18425 7f5a4cd4638ecdf28716050d9ad0d008 278 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 8 269 2.0E-94 T 15-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 C2I28_18425 7f5a4cd4638ecdf28716050d9ad0d008 278 SUPERFAMILY SSF161098 21 267 4.77E-56 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18425 7f5a4cd4638ecdf28716050d9ad0d008 278 Gene3D G3DSA:1.10.3720.10 19 273 1.8E-67 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18425 7f5a4cd4638ecdf28716050d9ad0d008 278 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 14 273 7.9E-126 T 15-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 C2I28_18425 7f5a4cd4638ecdf28716050d9ad0d008 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 267 3.4E-25 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_18220 64df399a72d2f60f3ceb0ce60246f437 160 Pfam PF03703 Bacterial PH domain 76 149 7.8E-14 T 15-10-2018 IPR005182 Domain of unknown function DUF304 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 15-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.5E-20 T 15-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.5E-20 T 15-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.5E-20 T 15-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 Pfam PF00255 Glutathione peroxidase 3 109 4.6E-42 T 15-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 SUPERFAMILY SSF52833 1 158 1.45E-61 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 Gene3D G3DSA:3.40.30.10 1 158 8.8E-72 T 15-10-2018 C2I28_17740 5b851aaabb10e8b4456d290d4f911bfd 158 PIRSF PIRSF000303 1 158 5.9E-67 T 15-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 C2I28_24685 b0d5a09b748af369d37751509c645877 236 SUPERFAMILY SSF46785 5 75 4.42E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24685 b0d5a09b748af369d37751509c645877 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.6E-15 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24685 b0d5a09b748af369d37751509c645877 236 SMART SM00345 7 66 1.3E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_24685 b0d5a09b748af369d37751509c645877 236 SUPERFAMILY SSF64288 76 228 1.38E-39 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_24685 b0d5a09b748af369d37751509c645877 236 Gene3D G3DSA:1.10.10.10 1 70 1.3E-20 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24685 b0d5a09b748af369d37751509c645877 236 SMART SM00866 87 226 1.7E-29 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_24685 b0d5a09b748af369d37751509c645877 236 Pfam PF07702 UTRA domain 90 223 3.2E-28 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_24685 b0d5a09b748af369d37751509c645877 236 Gene3D G3DSA:3.40.1410.10 71 236 9.0E-40 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 Gene3D G3DSA:1.10.1060.10 2 110 2.5E-10 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 Pfam PF02754 Cysteine-rich domain 326 411 6.7E-14 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 Pfam PF02754 Cysteine-rich domain 195 275 5.0E-18 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 PIRSF PIRSF000139 3 439 5.0E-140 T 15-10-2018 C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 Pfam PF13183 4Fe-4S dicluster domain 20 89 6.1E-12 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_21350 3c2b284627aade85411d3f7a23b78db5 439 SUPERFAMILY SSF46548 9 104 2.25E-17 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_13720 1aa3b600879db3151e08cddc8a3de2ff 335 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 101 313 9.4E-54 T 15-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 C2I28_13720 1aa3b600879db3151e08cddc8a3de2ff 335 Pfam PF01238 Phosphomannose isomerase type I 6 314 6.1E-50 T 15-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 C2I28_13720 1aa3b600879db3151e08cddc8a3de2ff 335 Gene3D G3DSA:2.60.120.10 229 314 5.7E-29 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_13720 1aa3b600879db3151e08cddc8a3de2ff 335 PIRSF PIRSF036894 2 316 2.2E-131 T 15-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 C2I28_13720 1aa3b600879db3151e08cddc8a3de2ff 335 Gene3D G3DSA:2.60.120.10 1 226 6.8E-94 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_13720 1aa3b600879db3151e08cddc8a3de2ff 335 SUPERFAMILY SSF51182 3 312 6.05E-104 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_00265 eed5ba29b4565d562e1d9eb8e38ea070 306 Pfam PF02517 CAAX protease self-immunity 149 244 5.5E-15 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 SUPERFAMILY SSF55282 3 178 8.95E-78 T 15-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 7.2E-42 T 15-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 15-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 PIRSF PIRSF002161 1 179 7.3E-69 T 15-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 Pfam PF00281 Ribosomal protein L5 24 80 2.5E-29 T 15-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.184 T 15-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08745 cf52a399bf0b215d2e03a4ef7621570f 179 Gene3D G3DSA:3.30.1440.10 1 179 3.9E-83 T 15-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08140 75cc9a1fc521153d16e08d5127710bf5 106 Pfam PF02575 YbaB/EbfC DNA-binding family 12 102 7.1E-36 T 15-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I28_08140 75cc9a1fc521153d16e08d5127710bf5 106 Gene3D G3DSA:3.30.1310.10 2 106 1.2E-39 T 15-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily C2I28_08140 75cc9a1fc521153d16e08d5127710bf5 106 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 106 9.2E-33 T 15-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I28_08140 75cc9a1fc521153d16e08d5127710bf5 106 SUPERFAMILY SSF82607 12 106 4.84E-35 T 15-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily C2I28_08140 75cc9a1fc521153d16e08d5127710bf5 106 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 23.271 T 15-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I28_08140 75cc9a1fc521153d16e08d5127710bf5 106 PIRSF PIRSF004555 4 106 5.4E-40 T 15-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family C2I28_12615 b67d5f8fe8b112108f3a5f1dfde610e9 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 239 4.0E-29 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_12615 b67d5f8fe8b112108f3a5f1dfde610e9 247 Gene3D G3DSA:1.10.3720.10 43 239 7.8E-26 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_12615 b67d5f8fe8b112108f3a5f1dfde610e9 247 SUPERFAMILY SSF161098 48 228 1.96E-32 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_20895 ba6a690080dfe611a404421ee3ec183d 199 ProSitePatterns PS00194 Thioredoxin family active site. 88 106 - T 15-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 C2I28_20895 ba6a690080dfe611a404421ee3ec183d 199 Gene3D G3DSA:3.40.30.10 29 199 1.5E-50 T 15-10-2018 C2I28_20895 ba6a690080dfe611a404421ee3ec183d 199 Pfam PF00578 AhpC/TSA family 61 179 1.0E-30 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_20895 ba6a690080dfe611a404421ee3ec183d 199 SUPERFAMILY SSF52833 57 195 1.45E-42 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 SUPERFAMILY SSF52172 1 131 3.42E-31 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 SUPERFAMILY SSF46894 147 207 3.4E-17 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 SMART SM00421 149 206 2.3E-18 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 Pfam PF00072 Response regulator receiver domain 5 116 2.9E-26 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 SMART SM00448 3 115 1.1E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 1.1E-16 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 Gene3D G3DSA:3.40.50.12740 3 210 1.1E-60 T 15-10-2018 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 4.4E-11 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 4.4E-11 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_21405 0a8621dbaf62f4f4a104fd615b6757ce 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 4.4E-11 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_06345 a2cf95fec0fa5768e00531b2ea6e7399 178 SUPERFAMILY SSF109604 14 137 1.98E-21 T 15-10-2018 C2I28_06345 a2cf95fec0fa5768e00531b2ea6e7399 178 TIGRFAM TIGR00277 HDIG: HDIG domain 22 91 3.7E-8 T 15-10-2018 IPR006675 HDIG domain C2I28_06345 a2cf95fec0fa5768e00531b2ea6e7399 178 Gene3D G3DSA:1.10.3210.10 5 170 2.4E-18 T 15-10-2018 C2I28_06345 a2cf95fec0fa5768e00531b2ea6e7399 178 Pfam PF01966 HD domain 25 135 9.0E-16 T 15-10-2018 IPR006674 HD domain C2I28_06345 a2cf95fec0fa5768e00531b2ea6e7399 178 SMART SM00471 19 148 3.9E-7 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_12570 d90c294b78af14e15cf2b90699cd3215 125 Gene3D G3DSA:3.10.129.10 1 125 5.7E-21 T 15-10-2018 C2I28_12570 d90c294b78af14e15cf2b90699cd3215 125 Pfam PF01575 MaoC like domain 12 103 2.0E-5 T 15-10-2018 IPR002539 MaoC-like dehydratase domain C2I28_12570 d90c294b78af14e15cf2b90699cd3215 125 SUPERFAMILY SSF54637 3 120 1.22E-21 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 SMART SM01091 336 414 1.3E-16 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 Pfam PF01595 Domain of unknown function DUF21 11 185 1.5E-49 T 15-10-2018 IPR002550 CNNM, transmembrane domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 Pfam PF03471 Transporter associated domain 337 411 1.2E-17 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 Gene3D G3DSA:3.10.580.10 184 331 1.5E-50 T 15-10-2018 C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 Pfam PF00571 CBS domain 269 321 2.0E-5 T 15-10-2018 IPR000644 CBS domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 Pfam PF00571 CBS domain 202 258 1.3E-5 T 15-10-2018 IPR000644 CBS domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 Gene3D G3DSA:3.30.465.10 332 412 4.3E-19 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 SMART SM00116 211 260 0.052 T 15-10-2018 IPR000644 CBS domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 SMART SM00116 273 321 13.0 T 15-10-2018 IPR000644 CBS domain C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 SUPERFAMILY SSF54631 197 339 6.7E-33 T 15-10-2018 C2I28_10940 f8034f89d9e18400aee2204a9ed871d2 421 SUPERFAMILY SSF56176 334 418 7.09E-18 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_18155 1e0a77559a36f277cd8c5f4d097408a9 240 SUPERFAMILY SSF82114 13 136 9.59E-33 T 15-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 C2I28_18155 1e0a77559a36f277cd8c5f4d097408a9 240 SMART SM00904 14 132 1.1E-32 T 15-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 C2I28_18155 1e0a77559a36f277cd8c5f4d097408a9 240 Pfam PF01687 Riboflavin kinase 14 129 1.3E-29 T 15-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 C2I28_18155 1e0a77559a36f277cd8c5f4d097408a9 240 Gene3D G3DSA:2.40.30.30 14 141 1.3E-36 T 15-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 C2I28_06680 8b347e6151d44c5bffdbc29b8f8b4a44 208 Gene3D G3DSA:3.40.50.360 1 208 3.5E-55 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_06680 8b347e6151d44c5bffdbc29b8f8b4a44 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.066 T 15-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I28_06680 8b347e6151d44c5bffdbc29b8f8b4a44 208 SUPERFAMILY SSF52218 4 207 3.19E-44 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_06680 8b347e6151d44c5bffdbc29b8f8b4a44 208 Pfam PF02525 Flavodoxin-like fold 4 203 1.6E-40 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 Pfam PF00202 Aminotransferase class-III 36 441 6.3E-126 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 23 442 8.8E-192 T 15-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 Gene3D G3DSA:3.40.640.10 72 339 4.6E-165 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 Gene3D G3DSA:3.90.1150.10 19 437 4.6E-165 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 PIRSF PIRSF000521 137 444 1.7E-35 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 PIRSF PIRSF000521 2 143 3.8E-8 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_01945 54640b0a53b2dd8c90bc9b2fc42b0c16 451 SUPERFAMILY SSF53383 33 442 2.42E-131 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 SMART SM00347 25 125 3.8E-26 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 Gene3D G3DSA:1.10.10.10 5 142 2.4E-31 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 Pfam PF01047 MarR family 33 89 6.1E-16 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 SUPERFAMILY SSF46785 13 138 9.37E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.6E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.6E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.6E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_06710 de28e966aaff29ed1093d0c63ce55c7d 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.6E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_11520 6c3204b5830b05d38bf6324e6492158b 281 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 216 1.3E-55 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_11520 6c3204b5830b05d38bf6324e6492158b 281 PIRSF PIRSF006483 2 281 1.6E-92 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_11520 6c3204b5830b05d38bf6324e6492158b 281 Gene3D G3DSA:3.30.70.120 194 269 4.1E-19 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_11520 6c3204b5830b05d38bf6324e6492158b 281 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 5.9E-19 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 33 77 2.6E-16 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 Pfam PF13377 Periplasmic binding protein-like domain 200 352 1.7E-24 T 15-10-2018 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 Gene3D G3DSA:3.40.50.2300 191 311 1.0E-63 T 15-10-2018 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 SMART SM00354 31 100 2.3E-30 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 Gene3D G3DSA:3.40.50.2300 94 335 1.0E-63 T 15-10-2018 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 SUPERFAMILY SSF53822 87 345 1.41E-58 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_24105 be3da894c36d4840db74cb97123f128f 357 SUPERFAMILY SSF47413 30 89 2.98E-15 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 Gene3D G3DSA:1.10.260.40 32 90 1.3E-19 T 15-10-2018 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 33 43 3.5E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_24105 be3da894c36d4840db74cb97123f128f 357 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 43 53 3.5E-5 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 147 333 3.0E-48 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 SUPERFAMILY SSF101215 3 83 1.37E-25 T 15-10-2018 IPR017944 KaiA/RbsU helical domain superfamily GO:0006468 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 11 83 4.5E-31 T 15-10-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 SMART SM00331 119 334 2.5E-57 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 11 91 3.0E-22 T 15-10-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 SUPERFAMILY SSF81606 125 332 2.22E-8 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 Gene3D G3DSA:3.60.40.10 86 334 1.2E-53 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09170 d4078cdc4e32f10b1ef1f725e108eee6 336 Gene3D G3DSA:1.10.1240.30 1 84 1.3E-27 T 15-10-2018 IPR017944 KaiA/RbsU helical domain superfamily GO:0006468 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 Gene3D G3DSA:1.10.3860.10 18 460 4.3E-102 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 7.6E-20 T 15-10-2018 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 7.6E-20 T 15-10-2018 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 PRINTS PR00173 Glutamate-aspartate symporter signature 28 48 7.6E-20 T 15-10-2018 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 7.6E-20 T 15-10-2018 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 7.6E-20 T 15-10-2018 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 7.6E-20 T 15-10-2018 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 SUPERFAMILY SSF118215 30 443 7.98E-92 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_17990 bba290e4e3d6df94284654250af652a0 464 Pfam PF00375 Sodium:dicarboxylate symporter family 32 442 4.1E-98 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_12490 9beaced68fcd3f3a937d1b73f7543240 287 Gene3D G3DSA:3.40.190.100 113 221 6.6E-85 T 15-10-2018 C2I28_12490 9beaced68fcd3f3a937d1b73f7543240 287 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 276 3.5E-66 T 15-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 C2I28_12490 9beaced68fcd3f3a937d1b73f7543240 287 SUPERFAMILY SSF53850 29 286 1.39E-74 T 15-10-2018 C2I28_12490 9beaced68fcd3f3a937d1b73f7543240 287 Gene3D G3DSA:3.40.190.10 33 284 6.6E-85 T 15-10-2018 C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 Gene3D G3DSA:3.40.50.300 11 329 7.2E-103 T 15-10-2018 C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 307 5.3E-21 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 4.1E-30 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 Pfam PF00005 ABC transporter 40 190 6.1E-31 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 SMART SM00382 48 240 4.5E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_17085 141c9a5991a1f7ae144487eccdcf4869 329 SUPERFAMILY SSF52540 13 261 1.57E-73 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 SUPERFAMILY SSF50249 1 64 1.54E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 SMART SM00357 3 66 1.4E-32 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 PIRSF PIRSF002599 1 66 3.6E-25 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.3E-31 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 Gene3D G3DSA:2.40.50.140 1 66 8.2E-31 T 15-10-2018 C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 PRINTS PR00050 Cold shock protein signature 24 33 1.3E-18 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 PRINTS PR00050 Cold shock protein signature 39 57 1.3E-18 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_24925 7fed34a8c7523114cf36f1aad806339c 66 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-18 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 SUPERFAMILY SSF53790 3 248 5.63E-84 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 5 239 2.6E-100 T 15-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 15-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 Gene3D G3DSA:3.30.950.10 120 256 3.0E-50 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 15-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 Gene3D G3DSA:3.40.1010.10 3 119 6.7E-46 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_13860 82d528390cdec0aec8a3a17f0a89fe72 256 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 216 7.2E-50 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_18310 d10b78ff94ad28281548f2e86cfbed02 156 Pfam PF12638 Staygreen protein 3 145 6.9E-45 T 15-10-2018 IPR024438 Staygreen protein C2I28_01635 987c9258954c13010b1acc94bda247b8 401 SUPERFAMILY SSF82171 51 379 7.85E-16 T 15-10-2018 C2I28_01635 987c9258954c13010b1acc94bda247b8 401 Gene3D G3DSA:2.120.10.30 23 269 2.4E-9 T 15-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I28_26970 d856825543489ea53209b0ff731d4743 408 Pfam PF07690 Major Facilitator Superfamily 22 359 1.1E-35 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_26970 d856825543489ea53209b0ff731d4743 408 SUPERFAMILY SSF103473 19 401 5.75E-43 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_26970 d856825543489ea53209b0ff731d4743 408 Gene3D G3DSA:1.20.1250.20 15 403 9.5E-42 T 15-10-2018 C2I28_03915 9c9c962b206c535f0f881a8157ec3734 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 1.1E-26 T 15-10-2018 IPR020390 Uncharacterised protein family YqhV C2I28_03915 9c9c962b206c535f0f881a8157ec3734 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 76 4.0E-8 T 15-10-2018 IPR020390 Uncharacterised protein family YqhV C2I28_00305 e9e95c1c412a3cc29042d777778d8910 472 Pfam PF03616 Sodium/glutamate symporter 7 345 2.9E-17 T 15-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 C2I28_16825 a94a384e397948723296f4165873040c 311 Gene3D G3DSA:1.20.1510.10 21 211 1.0E-43 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_16825 a94a384e397948723296f4165873040c 311 Gene3D G3DSA:3.30.70.1350 215 292 3.5E-6 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_16825 a94a384e397948723296f4165873040c 311 SUPERFAMILY SSF160240 217 292 8.11E-13 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_16825 a94a384e397948723296f4165873040c 311 Pfam PF01545 Cation efflux family 23 211 2.3E-47 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_16825 a94a384e397948723296f4165873040c 311 SUPERFAMILY SSF161111 22 212 3.53E-53 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_16825 a94a384e397948723296f4165873040c 311 Pfam PF16916 Dimerisation domain of Zinc Transporter 220 290 7.0E-7 T 15-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain C2I28_16825 a94a384e397948723296f4165873040c 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 293 1.6E-85 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_21175 d26892db2c434d178a33cb296408a402 374 Pfam PF11761 Cobalamin biosynthesis central region 155 249 1.3E-13 T 15-10-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 C2I28_21175 d26892db2c434d178a33cb296408a402 374 SUPERFAMILY SSF159672 15 259 1.06E-57 T 15-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 C2I28_21175 d26892db2c434d178a33cb296408a402 374 SUPERFAMILY SSF159664 245 372 6.02E-38 T 15-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 C2I28_21175 d26892db2c434d178a33cb296408a402 374 Pfam PF01890 Cobalamin synthesis G C-terminus 252 369 3.4E-34 T 15-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 C2I28_21175 d26892db2c434d178a33cb296408a402 374 Pfam PF11760 Cobalamin synthesis G N-terminal 70 149 4.2E-35 T 15-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 C2I28_21175 d26892db2c434d178a33cb296408a402 374 Gene3D G3DSA:3.40.50.11220 11 144 5.4E-33 T 15-10-2018 C2I28_21175 d26892db2c434d178a33cb296408a402 374 Gene3D G3DSA:3.30.420.180 242 373 1.5E-39 T 15-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 C2I28_23440 39429d713decf0502f1acc0e9f04398d 254 Pfam PF13673 Acetyltransferase (GNAT) domain 137 242 2.6E-9 T 15-10-2018 IPR000182 GNAT domain C2I28_23440 39429d713decf0502f1acc0e9f04398d 254 Gene3D G3DSA:3.40.630.30 26 245 7.5E-19 T 15-10-2018 C2I28_23440 39429d713decf0502f1acc0e9f04398d 254 SUPERFAMILY SSF55729 119 248 1.72E-17 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_12595 1fe64d09b885975e819183e05dfa3130 336 Gene3D G3DSA:3.20.20.70 1 231 7.4E-66 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_12595 1fe64d09b885975e819183e05dfa3130 336 SUPERFAMILY SSF51445 1 229 1.54E-56 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_12595 1fe64d09b885975e819183e05dfa3130 336 Pfam PF05913 Bacterial protein of unknown function (DUF871) 1 333 6.7E-94 T 15-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic C2I28_12595 1fe64d09b885975e819183e05dfa3130 336 Gene3D G3DSA:2.40.100.10 235 336 4.3E-31 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_12595 1fe64d09b885975e819183e05dfa3130 336 SUPERFAMILY SSF50891 242 334 4.55E-26 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_01820 d8cecaf726855526eef430b668c61edc 294 SUPERFAMILY SSF52266 56 263 1.83E-39 T 15-10-2018 C2I28_01820 d8cecaf726855526eef430b668c61edc 294 Gene3D G3DSA:3.40.50.1110 26 265 9.3E-39 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_01820 d8cecaf726855526eef430b668c61edc 294 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 60 252 4.2E-31 T 15-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I28_26550 b73096ff55292a1b78610447e10ce517 389 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 337 361 - T 15-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_26550 b73096ff55292a1b78610447e10ce517 389 Pfam PF01098 Cell cycle protein 13 379 6.5E-88 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 PIRSF PIRSF002401 1 376 1.7E-142 T 15-10-2018 IPR035101 GTP-binding protein, Obg-type C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 15-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.3E-14 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 SUPERFAMILY SSF52540 160 331 1.67E-51 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 5.2E-142 T 15-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 1.0E-25 T 15-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 47.925 T 15-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 SUPERFAMILY SSF82051 1 157 1.7E-55 T 15-10-2018 IPR036726 GTP1/OBG domain superfamily C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Gene3D G3DSA:2.40.240.60 356 428 2.6E-18 T 15-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 9.2E-27 T 15-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.6E-34 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.6E-34 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.6E-34 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.6E-34 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Gene3D G3DSA:3.40.50.300 158 342 8.8E-62 T 15-10-2018 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Pfam PF01018 GTP1/OBG 3 157 1.5E-59 T 15-10-2018 IPR006169 GTP1/OBG domain C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 4.5E-23 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 Gene3D G3DSA:2.70.210.12 1 157 7.0E-61 T 15-10-2018 IPR036726 GTP1/OBG domain superfamily C2I28_04835 609ac17b6a45fe843a29d103d4116b12 428 SUPERFAMILY SSF102741 356 428 1.44E-23 T 15-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily C2I28_00915 23e22f48c976271dcd6050461fae2696 255 SUPERFAMILY SSF52540 5 225 2.03E-70 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_00915 23e22f48c976271dcd6050461fae2696 255 Gene3D G3DSA:3.40.50.300 1 247 3.9E-68 T 15-10-2018 C2I28_00915 23e22f48c976271dcd6050461fae2696 255 Pfam PF00005 ABC transporter 24 172 1.0E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_00915 23e22f48c976271dcd6050461fae2696 255 SMART SM00382 33 228 2.8E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_19105 826751e10fc64b2782987d7eafd58fa0 375 Gene3D G3DSA:1.20.1740.10 12 374 3.5E-15 T 15-10-2018 C2I28_19105 826751e10fc64b2782987d7eafd58fa0 375 Pfam PF03845 Spore germination protein 16 338 8.1E-107 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_19105 826751e10fc64b2782987d7eafd58fa0 375 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 16 368 1.9E-85 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_24330 0a0de677573d5f032511ca0d75d7879b 190 SUPERFAMILY SSF55729 1 175 2.53E-48 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24330 0a0de677573d5f032511ca0d75d7879b 190 Gene3D G3DSA:3.40.630.30 1 178 3.8E-53 T 15-10-2018 C2I28_24330 0a0de677573d5f032511ca0d75d7879b 190 Pfam PF13302 Acetyltransferase (GNAT) domain 7 151 6.2E-28 T 15-10-2018 IPR000182 GNAT domain C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 SUPERFAMILY SSF55486 9 499 1.95E-119 T 15-10-2018 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 Gene3D G3DSA:1.10.1370.30 3 505 5.6E-210 T 15-10-2018 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 406 427 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 383 400 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 152 172 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 451 469 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 337 356 9.0E-80 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 PIRSF PIRSF006615 4 505 3.5E-197 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_15265 fba0c6de5880c387b12d76bf1a1872a8 505 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 4 499 4.6E-216 T 15-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 C2I28_13100 512e84d8e46d50bd064114d41609574f 474 Gene3D G3DSA:3.30.450.20 155 286 3.4E-5 T 15-10-2018 C2I28_13100 512e84d8e46d50bd064114d41609574f 474 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 295 463 3.3E-48 T 15-10-2018 IPR000160 GGDEF domain C2I28_13100 512e84d8e46d50bd064114d41609574f 474 Pfam PF07694 5TMR of 5TMR-LYT 4 128 3.0E-9 T 15-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 C2I28_13100 512e84d8e46d50bd064114d41609574f 474 SUPERFAMILY SSF55073 304 465 4.71E-46 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_13100 512e84d8e46d50bd064114d41609574f 474 SMART SM00267 288 464 2.6E-62 T 15-10-2018 IPR000160 GGDEF domain C2I28_13100 512e84d8e46d50bd064114d41609574f 474 Gene3D G3DSA:3.30.70.270 287 466 2.5E-53 T 15-10-2018 C2I28_13100 512e84d8e46d50bd064114d41609574f 474 Pfam PF00990 Diguanylate cyclase, GGDEF domain 301 460 7.8E-48 T 15-10-2018 IPR000160 GGDEF domain C2I28_07610 22518792fd56f96972fcd77dcac852b6 105 ProDom PD705231 YWDI GROUP-SPECIFIC 1 105 9.0E-5 T 15-10-2018 IPR035218 Protein of unknown function DUF5327 C2I28_07610 22518792fd56f96972fcd77dcac852b6 105 Pfam PF17261 Family of unknown function (DUF5327) 1 105 9.3E-24 T 15-10-2018 IPR035218 Protein of unknown function DUF5327 C2I28_17685 831ac65d8a8fa171ef89641cb39ae17f 243 Gene3D G3DSA:3.20.20.370 29 241 2.1E-73 T 15-10-2018 C2I28_17685 831ac65d8a8fa171ef89641cb39ae17f 243 Pfam PF01522 Polysaccharide deacetylase 47 156 1.8E-33 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_17685 831ac65d8a8fa171ef89641cb39ae17f 243 SUPERFAMILY SSF88713 40 240 1.93E-63 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_22915 68807c68d4bf4cb4b366109ca0493ae1 255 Pfam PF04240 Carotenoid biosynthesis protein 34 240 1.9E-40 T 15-10-2018 IPR007354 Carotene biosynthesis associated membrane protein C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 Pfam PF00905 Penicillin binding protein transpeptidase domain 355 643 2.2E-45 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 Gene3D G3DSA:1.10.3810.10 98 292 1.7E-211 T 15-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 Pfam PF00912 Transglycosylase 89 264 2.3E-65 T 15-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 SUPERFAMILY SSF56601 246 703 2.62E-106 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 SUPERFAMILY SSF53955 76 288 5.62E-74 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 Gene3D G3DSA:3.90.1310.20 82 541 1.7E-211 T 15-10-2018 C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 Gene3D G3DSA:3.40.710.10 328 659 1.7E-211 T 15-10-2018 C2I28_15055 1a61ac76906201e3b5f84cc3b80bcb83 941 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 98 648 1.3E-176 T 15-10-2018 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 Pfam PF07702 UTRA domain 96 228 4.4E-23 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 Gene3D G3DSA:3.40.1410.10 80 236 1.1E-26 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 SMART SM00866 94 231 3.9E-12 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 SMART SM00345 14 73 1.2E-14 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 SUPERFAMILY SSF64288 61 236 6.91E-31 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 SUPERFAMILY SSF46785 6 83 2.89E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 6.1E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.5E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.5E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_26745 a727ef7d1ff2955a741d4c8dc3f09509 238 Gene3D G3DSA:1.10.10.10 1 79 1.0E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05925 d0178564f9194810c74a27b1fabbd1d4 395 SMART SM00833 256 371 2.1E-51 T 15-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I28_05925 d0178564f9194810c74a27b1fabbd1d4 395 Gene3D G3DSA:3.30.1220.10 238 371 2.8E-6 T 15-10-2018 IPR036627 CobW-like, C-terminal domain superfamily C2I28_05925 d0178564f9194810c74a27b1fabbd1d4 395 SUPERFAMILY SSF52540 2 303 1.17E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05925 d0178564f9194810c74a27b1fabbd1d4 395 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 7.1E-59 T 15-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain C2I28_05925 d0178564f9194810c74a27b1fabbd1d4 395 Gene3D G3DSA:3.40.50.300 1 228 1.0E-72 T 15-10-2018 C2I28_05925 d0178564f9194810c74a27b1fabbd1d4 395 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 371 2.5E-28 T 15-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I28_13620 5fbd04be7ae1bb30afb82dbc0e669a43 40 SUPERFAMILY SSF47406 9 35 3.01E-8 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_13620 5fbd04be7ae1bb30afb82dbc0e669a43 40 Pfam PF08671 Anti-repressor SinI 9 35 1.2E-12 T 15-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 SUPERFAMILY SSF49785 20 232 2.67E-64 T 15-10-2018 IPR008979 Galactose-binding-like domain superfamily C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 398 423 - T 15-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 59 231 9.7E-44 T 15-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Pfam PF00703 Glycosyl hydrolases family 2 233 345 7.9E-17 T 15-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Gene3D G3DSA:2.60.40.10 233 345 2.7E-30 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 SUPERFAMILY SSF74650 750 1033 9.73E-90 T 15-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 SUPERFAMILY SSF49303 233 345 3.12E-26 T 15-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Gene3D G3DSA:2.60.120.260 16 232 8.8E-92 T 15-10-2018 IPR008979 Galactose-binding-like domain superfamily C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 SMART SM01038 763 1032 8.8E-112 T 15-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Gene3D G3DSA:2.60.40.10 635 739 1.7E-26 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Pfam PF16353 Domain of unknown function(DUF4981) 650 738 1.8E-21 T 15-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 SUPERFAMILY SSF51445 347 635 1.26E-93 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Gene3D G3DSA:2.70.98.10 747 1031 2.0E-92 T 15-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 347 638 1.0E-115 T 15-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Gene3D G3DSA:3.20.20.80 347 633 1.6E-108 T 15-10-2018 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 Pfam PF02929 Beta galactosidase small chain 765 1031 1.6E-77 T 15-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 SUPERFAMILY SSF49303 631 740 9.35E-27 T 15-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 541 556 2.6E-39 T 15-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 159 174 2.6E-39 T 15-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 356 370 2.6E-39 T 15-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 467 482 2.6E-39 T 15-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 PRINTS PR00132 Glycosyl hydrolase family 2 signature 388 406 2.6E-39 T 15-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_18680 69b16e4dd6203487ba449ac8d915dcd8 1034 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 467 481 - T 15-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 C2I28_20050 6de65e517647ed0fae8fe7a995a97b1b 402 Gene3D G3DSA:1.20.1250.20 208 401 9.7E-21 T 15-10-2018 C2I28_20050 6de65e517647ed0fae8fe7a995a97b1b 402 Pfam PF07690 Major Facilitator Superfamily 24 335 1.5E-39 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_20050 6de65e517647ed0fae8fe7a995a97b1b 402 Gene3D G3DSA:1.20.1250.20 17 198 4.4E-29 T 15-10-2018 C2I28_20050 6de65e517647ed0fae8fe7a995a97b1b 402 SUPERFAMILY SSF103473 16 398 2.49E-63 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_19820 b2a2d8dd4292a9fcf59110093b59b122 87 Pfam PF06949 Protein of unknown function (DUF1292) 15 84 4.1E-11 T 15-10-2018 IPR009711 Uncharacterised protein family UPF0473 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 SMART SM00493 3 103 1.1E-32 T 15-10-2018 IPR006171 TOPRIM domain C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 SUPERFAMILY SSF56712 4 589 9.03E-200 T 15-10-2018 IPR023405 DNA topoisomerase, type IA, core domain C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 616 655 3.0E-13 T 15-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 576 613 6.3E-17 T 15-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 8.7E-37 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 8.7E-37 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 8.7E-37 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 8.7E-37 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 8.7E-37 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Pfam PF01751 Toprim domain 5 113 2.4E-29 T 15-10-2018 IPR006171 TOPRIM domain C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Pfam PF02150 RNA polymerases M/15 Kd subunit 660 691 1.2E-6 T 15-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 SMART SM00437 242 510 2.1E-126 T 15-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 SMART SM00436 104 192 5.3E-50 T 15-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Gene3D G3DSA:2.70.20.10 184 457 6.5E-169 T 15-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 15-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 SUPERFAMILY SSF57783 576 613 5.27E-14 T 15-10-2018 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Gene3D G3DSA:3.40.50.140 1 134 1.1E-53 T 15-10-2018 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Gene3D G3DSA:1.10.290.10 250 385 6.5E-169 T 15-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 642 56.39 T 15-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Pfam PF01131 DNA topoisomerase 128 548 2.7E-136 T 15-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 2.3E-269 T 15-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Gene3D G3DSA:3.30.65.10 559 617 6.8E-15 T 15-10-2018 C2I28_02575 1c6d21c0b9cb4c3a85f73274445ef832 691 Gene3D G3DSA:1.10.460.10 135 550 6.5E-169 T 15-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 C2I28_25005 cb1eed3ddc42a9f19909aae944723c3f 314 PIRSF PIRSF016839 1 314 2.1E-55 T 15-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 C2I28_25005 cb1eed3ddc42a9f19909aae944723c3f 314 Gene3D G3DSA:3.20.20.140 2 314 1.4E-103 T 15-10-2018 C2I28_25005 cb1eed3ddc42a9f19909aae944723c3f 314 SUPERFAMILY SSF51556 1 312 1.75E-75 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_25005 cb1eed3ddc42a9f19909aae944723c3f 314 Pfam PF02126 Phosphotriesterase family 11 312 1.2E-82 T 15-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 Gene3D G3DSA:3.40.50.2300 62 308 1.8E-99 T 15-10-2018 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 Gene3D G3DSA:3.40.50.2300 161 291 1.8E-99 T 15-10-2018 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 6.8E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.8E-6 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 SMART SM00354 2 72 6.3E-38 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 6.9E-18 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 Gene3D G3DSA:1.10.260.40 1 60 4.1E-28 T 15-10-2018 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 SUPERFAMILY SSF47413 3 60 3.87E-19 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 TIGRFAM TIGR01481 ccpA: catabolite control protein A 2 332 2.0E-160 T 15-10-2018 IPR006377 Catabolite control protein A GO:0006355 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 15-10-2018 C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 SUPERFAMILY SSF53822 62 332 5.89E-90 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_05640 e69ca270957c87f66d9dffb8fe61c2ec 332 Pfam PF13377 Periplasmic binding protein-like domain 169 331 9.4E-35 T 15-10-2018 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 SUPERFAMILY SSF47203 229 377 5.68E-62 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 SUPERFAMILY SSF56645 2 242 4.71E-79 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 Gene3D G3DSA:1.10.540.10 1 119 3.9E-44 T 15-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 PIRSF PIRSF016578 2 377 1.2E-28 T 15-10-2018 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 Gene3D G3DSA:1.20.140.10 235 379 6.9E-60 T 15-10-2018 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.9E-56 T 15-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.2E-36 T 15-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 Gene3D G3DSA:2.40.110.10 121 234 7.4E-36 T 15-10-2018 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 15-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 C2I28_04255 2a43e479ddd7c7c8d542e66cceb041cc 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.4E-23 T 15-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 C2I28_00815 87c6edf934b218fb9245b251e40055e8 336 Gene3D G3DSA:3.20.20.100 4 323 1.4E-62 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_00815 87c6edf934b218fb9245b251e40055e8 336 SUPERFAMILY SSF51430 8 325 2.36E-60 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_00815 87c6edf934b218fb9245b251e40055e8 336 Pfam PF00248 Aldo/keto reductase family 8 321 5.6E-51 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_04525 6dcce239eb6ef488f041fb5b3e4f3540 307 Gene3D G3DSA:3.40.50.1100 10 299 3.5E-112 T 15-10-2018 C2I28_04525 6dcce239eb6ef488f041fb5b3e4f3540 307 Gene3D G3DSA:3.40.50.1100 45 146 3.5E-112 T 15-10-2018 C2I28_04525 6dcce239eb6ef488f041fb5b3e4f3540 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 8.3E-63 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_04525 6dcce239eb6ef488f041fb5b3e4f3540 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 15-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I28_04525 6dcce239eb6ef488f041fb5b3e4f3540 307 SUPERFAMILY SSF53686 1 301 9.69E-89 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_21330 3a1b5e9af772c8bad43c65da71f2da82 134 Pfam PF06803 Protein of unknown function (DUF1232) 59 94 2.6E-13 T 15-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I28_21330 3a1b5e9af772c8bad43c65da71f2da82 134 PIRSF PIRSF031804 1 124 1.6E-39 T 15-10-2018 IPR016983 Uncharacterised conserved protein UCP031804 C2I28_22610 2dc7f2a3ec7a13bdae3a8703c902ee75 253 SUPERFAMILY SSF55166 89 238 2.2E-38 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_22610 2dc7f2a3ec7a13bdae3a8703c902ee75 253 Gene3D G3DSA:3.30.1380.10 40 253 1.1E-75 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_22610 2dc7f2a3ec7a13bdae3a8703c902ee75 253 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 103 231 1.6E-42 T 15-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I28_15785 70944d32384759e86ae01119630e1911 486 Pfam PF07690 Major Facilitator Superfamily 9 401 2.5E-56 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_15785 70944d32384759e86ae01119630e1911 486 SUPERFAMILY SSF103473 2 477 2.22E-71 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15785 70944d32384759e86ae01119630e1911 486 Gene3D G3DSA:1.20.1720.10 5 214 3.3E-54 T 15-10-2018 C2I28_15785 70944d32384759e86ae01119630e1911 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 5.9E-10 T 15-10-2018 C2I28_15785 70944d32384759e86ae01119630e1911 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 8 32 5.9E-10 T 15-10-2018 C2I28_15785 70944d32384759e86ae01119630e1911 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 67 89 5.9E-10 T 15-10-2018 C2I28_15785 70944d32384759e86ae01119630e1911 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 194 212 5.9E-10 T 15-10-2018 C2I28_15785 70944d32384759e86ae01119630e1911 486 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 5.9E-10 T 15-10-2018 C2I28_15785 70944d32384759e86ae01119630e1911 486 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 413 6.3E-69 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_15785 70944d32384759e86ae01119630e1911 486 Gene3D G3DSA:1.20.1250.20 251 483 7.8E-22 T 15-10-2018 C2I28_05365 64b0c1042f51811d863b84cd314f1a15 209 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 5 209 1.1E-71 T 15-10-2018 IPR014205 Sporulation protein YtaF C2I28_05365 64b0c1042f51811d863b84cd314f1a15 209 Pfam PF02659 Putative manganese efflux pump 122 206 2.1E-9 T 15-10-2018 IPR003810 Putative manganese efflux pump C2I28_05365 64b0c1042f51811d863b84cd314f1a15 209 Pfam PF02659 Putative manganese efflux pump 5 82 3.4E-10 T 15-10-2018 IPR003810 Putative manganese efflux pump C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 SUPERFAMILY SSF53686 13 366 6.94E-101 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 SUPERFAMILY SSF55021 340 414 6.87E-11 T 15-10-2018 C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 Gene3D G3DSA:3.40.1020.10 329 423 4.4E-10 T 15-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 TIGRFAM TIGR02079 THD1: threonine dehydratase 16 423 7.8E-195 T 15-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 317 2.6E-74 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 330 419 7.8E-27 T 15-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 Gene3D G3DSA:3.40.50.1100 25 328 1.5E-117 T 15-10-2018 C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 Gene3D G3DSA:3.40.50.1100 60 159 1.5E-117 T 15-10-2018 C2I28_01845 7b70fe18a9d9fa42f83489a887631ea9 423 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 15-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 SMART SM00382 29 218 1.4E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 Gene3D G3DSA:3.40.50.300 1 239 5.6E-75 T 15-10-2018 C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 Pfam PF00005 ABC transporter 21 162 1.3E-27 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 Gene3D G3DSA:2.40.50.100 240 362 2.7E-31 T 15-10-2018 C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 Gene3D G3DSA:2.40.50.140 303 348 2.7E-31 T 15-10-2018 C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 SUPERFAMILY SSF50331 237 365 2.26E-27 T 15-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 SUPERFAMILY SSF52540 4 243 6.3E-85 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_10955 f56ba655640b6d1d4b38fd22bb0f3ca6 369 Pfam PF08402 TOBE domain 281 356 2.2E-4 T 15-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 C2I28_14395 9510163056ce9fb8d1736217658d54c3 532 PIRSF PIRSF005690 35 532 1.5E-190 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_14395 9510163056ce9fb8d1736217658d54c3 532 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 51 517 4.8E-199 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_02560 12916218a0394668698a8dabfeb9d592 180 SUPERFAMILY SSF56235 3 179 6.92E-60 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_02560 12916218a0394668698a8dabfeb9d592 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.15 T 15-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 C2I28_02560 12916218a0394668698a8dabfeb9d592 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 1.5E-83 T 15-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 C2I28_02560 12916218a0394668698a8dabfeb9d592 180 Pfam PF00227 Proteasome subunit 4 178 3.1E-25 T 15-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 C2I28_02560 12916218a0394668698a8dabfeb9d592 180 PIRSF PIRSF039093 1 180 8.4E-85 T 15-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 C2I28_02560 12916218a0394668698a8dabfeb9d592 180 Gene3D G3DSA:3.60.20.10 2 180 4.7E-68 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 Gene3D G3DSA:3.40.190.290 91 287 2.2E-36 T 15-10-2018 C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-18 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 Gene3D G3DSA:1.10.10.10 1 89 9.7E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 Pfam PF03466 LysR substrate binding domain 87 283 4.6E-37 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 SUPERFAMILY SSF53850 89 283 4.34E-35 T 15-10-2018 C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24455 0d2e77077e235366fa3d1e8e1a8c87d2 288 SUPERFAMILY SSF46785 1 111 1.47E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23900 a573b07b17f9c07f0b4b1592bd21f9cd 136 Pfam PF02600 Disulfide bond formation protein DsbB 6 128 1.1E-11 T 15-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 C2I28_23900 a573b07b17f9c07f0b4b1592bd21f9cd 136 SUPERFAMILY SSF158442 6 129 9.55E-31 T 15-10-2018 IPR023380 DsbB-like superfamily C2I28_23900 a573b07b17f9c07f0b4b1592bd21f9cd 136 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 2 133 22.113 T 15-10-2018 IPR012187 Disulphide bond formation protein BdbC C2I28_23900 a573b07b17f9c07f0b4b1592bd21f9cd 136 PIRSF PIRSF036659 1 136 2.0E-53 T 15-10-2018 IPR012187 Disulphide bond formation protein BdbC C2I28_23900 a573b07b17f9c07f0b4b1592bd21f9cd 136 Gene3D G3DSA:1.20.1550.10 2 109 5.2E-11 T 15-10-2018 IPR023380 DsbB-like superfamily C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 121 5.4E-55 T 15-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 Hamap MF_01953 Urease subunit alpha [ureC]. 3 569 57.932 T 15-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 SUPERFAMILY SSF51556 131 569 1.53E-201 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 ProSitePatterns PS00145 Urease active site. 319 335 - T 15-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 ProSitePatterns PS01120 Urease nickel ligands signature. 129 142 - T 15-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 SUPERFAMILY SSF51338 424 479 4.1E-6 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 Gene3D G3DSA:2.30.40.10 5 482 3.7E-294 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 Gene3D G3DSA:3.20.20.140 131 569 3.7E-294 T 15-10-2018 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 403 418 5.1E-35 T 15-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 297 314 5.1E-35 T 15-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 336 352 5.1E-35 T 15-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 429 442 5.1E-35 T 15-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 SUPERFAMILY SSF51338 4 179 5.28E-59 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 Pfam PF01979 Amidohydrolase family 127 455 6.5E-81 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_22950 59ec9a034d9bfb2bc52fa651be3e7067 569 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 569 0.0 T 15-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_13065 89844c635cbe5178c35f2b37846fa5a2 210 Gene3D G3DSA:3.40.50.720 1 208 1.5E-48 T 15-10-2018 C2I28_13065 89844c635cbe5178c35f2b37846fa5a2 210 SUPERFAMILY SSF51735 1 208 1.14E-29 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_13065 89844c635cbe5178c35f2b37846fa5a2 210 Pfam PF13460 NAD(P)H-binding 7 194 2.6E-22 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_17550 2b5c0b9343aa5c302bc06b0a5470ffeb 260 Pfam PF07907 YibE/F-like protein 4 243 3.5E-75 T 15-10-2018 IPR012507 YibE/F-like C2I28_17550 2b5c0b9343aa5c302bc06b0a5470ffeb 260 PIRSF PIRSF031503 1 260 3.5E-95 T 15-10-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 SUPERFAMILY SSF46785 1 110 4.55E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 Pfam PF03466 LysR substrate binding domain 89 289 4.5E-50 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 SUPERFAMILY SSF53850 90 290 4.4E-45 T 15-10-2018 C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 Gene3D G3DSA:3.40.190.290 90 291 1.6E-57 T 15-10-2018 C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 Gene3D G3DSA:1.10.10.10 1 82 2.6E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_14575 d319f374dc063d131c5dd37a67efaa60 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.5E-22 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_27450 b2518ab579cc25a662b83d234fbb05bc 296 Gene3D G3DSA:3.90.25.10 170 287 4.2E-63 T 15-10-2018 C2I28_27450 b2518ab579cc25a662b83d234fbb05bc 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 229 8.7E-37 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_27450 b2518ab579cc25a662b83d234fbb05bc 296 SUPERFAMILY SSF51735 4 296 4.38E-54 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_27450 b2518ab579cc25a662b83d234fbb05bc 296 Gene3D G3DSA:3.40.50.720 8 281 4.2E-63 T 15-10-2018 C2I28_01295 da9a1ab03758348aada3b286fe30670c 322 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 94 237 5.2E-47 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_01295 da9a1ab03758348aada3b286fe30670c 322 Gene3D G3DSA:1.10.260.150 71 322 5.3E-81 T 15-10-2018 C2I28_01295 da9a1ab03758348aada3b286fe30670c 322 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 237 1.1E-33 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_21355 e9ef2822df88e08654135a52611ed770 470 SUPERFAMILY SSF56176 5 217 1.82E-70 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 Gene3D G3DSA:3.30.70.2740 336 417 3.5E-15 T 15-10-2018 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 Pfam PF01565 FAD binding domain 41 179 8.7E-42 T 15-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 Gene3D G3DSA:3.30.465.40 4 238 8.7E-77 T 15-10-2018 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 SUPERFAMILY SSF55103 220 460 2.29E-67 T 15-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 1.1E-71 T 15-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 Gene3D G3DSA:1.10.45.10 418 458 4.3E-11 T 15-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 C2I28_21355 e9ef2822df88e08654135a52611ed770 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 7.3E-176 T 15-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 C2I28_10740 60d91c23b51c10952f5f61d6150638b1 176 Gene3D G3DSA:3.10.450.420 23 176 1.4E-52 T 15-10-2018 C2I28_10740 60d91c23b51c10952f5f61d6150638b1 176 Pfam PF16800 IseA DL-endopeptidase inhibitor 27 174 3.2E-52 T 15-10-2018 IPR031841 DL-endopeptidase inhibitor IseA C2I28_20065 eee1ea288cbed379269c915b0e933465 339 Gene3D G3DSA:3.30.750.24 216 335 2.7E-25 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 Pfam PF00209 Sodium:neurotransmitter symporter family 4 122 3.5E-40 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 Pfam PF00209 Sodium:neurotransmitter symporter family 124 480 1.0E-76 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 SUPERFAMILY SSF161070 4 487 1.7E-148 T 15-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 389 409 5.3E-27 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 312 331 5.3E-27 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 5.3E-27 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 5.3E-27 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06495 d4eebce9fb94b5a1132e3a9d0a98a98f 504 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 5.3E-27 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_06725 0a5ca975762434f13accff188ceba3cc 154 Gene3D G3DSA:3.90.1170.40 3 148 1.3E-54 T 15-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I28_06725 0a5ca975762434f13accff188ceba3cc 154 SUPERFAMILY SSF54690 5 138 2.48E-45 T 15-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I28_06725 0a5ca975762434f13accff188ceba3cc 154 Pfam PF02391 MoaE protein 10 119 1.9E-36 T 15-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 C2I28_04180 70e58a00291092bef8ece243f7f70184 110 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 109 4.0E-14 T 15-10-2018 IPR020506 Uncharacterised protein family YqfZ C2I28_01220 24c0fe22c183057c7529bd78b08a449b 306 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 2.1E-15 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_01220 24c0fe22c183057c7529bd78b08a449b 306 Gene3D G3DSA:1.10.357.10 1 189 2.0E-26 T 15-10-2018 C2I28_01220 24c0fe22c183057c7529bd78b08a449b 306 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_01220 24c0fe22c183057c7529bd78b08a449b 306 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 4.4E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_01220 24c0fe22c183057c7529bd78b08a449b 306 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 4.4E-8 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_01220 24c0fe22c183057c7529bd78b08a449b 306 SUPERFAMILY SSF46689 3 66 3.44E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_27095 bee203837141f9ee01423a5ce2a85bd9 82 Pfam PF17362 Family of unknown function 5 80 2.6E-17 T 15-10-2018 IPR020270 Uncharacterised protein family, plasmid pXO2-34 C2I28_27195 bee203837141f9ee01423a5ce2a85bd9 82 Pfam PF17362 Family of unknown function 5 80 2.6E-17 T 15-10-2018 IPR020270 Uncharacterised protein family, plasmid pXO2-34 C2I28_26245 bee203837141f9ee01423a5ce2a85bd9 82 Pfam PF17362 Family of unknown function 5 80 2.6E-17 T 15-10-2018 IPR020270 Uncharacterised protein family, plasmid pXO2-34 C2I28_26345 bee203837141f9ee01423a5ce2a85bd9 82 Pfam PF17362 Family of unknown function 5 80 2.6E-17 T 15-10-2018 IPR020270 Uncharacterised protein family, plasmid pXO2-34 C2I28_07210 be82d217a06aca39d1b4585bdc24c559 509 SUPERFAMILY SSF117892 69 211 1.22E-33 T 15-10-2018 IPR036013 Band 7/SPFH domain superfamily C2I28_07210 be82d217a06aca39d1b4585bdc24c559 509 Pfam PF15975 Flotillin 369 464 1.3E-14 T 15-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 C2I28_07210 be82d217a06aca39d1b4585bdc24c559 509 Gene3D G3DSA:3.30.479.30 78 194 3.8E-37 T 15-10-2018 C2I28_07210 be82d217a06aca39d1b4585bdc24c559 509 Pfam PF01145 SPFH domain / Band 7 family 31 221 2.3E-24 T 15-10-2018 IPR001107 Band 7 domain C2I28_07210 be82d217a06aca39d1b4585bdc24c559 509 SMART SM00244 120 302 1.8E-8 T 15-10-2018 IPR001107 Band 7 domain C2I28_07225 9805859d585b7a8826017b772b3976a5 294 Pfam PF00483 Nucleotidyl transferase 5 266 1.1E-31 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_07225 9805859d585b7a8826017b772b3976a5 294 SUPERFAMILY SSF53448 3 276 2.5E-68 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_07225 9805859d585b7a8826017b772b3976a5 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 265 7.5E-120 T 15-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I28_07225 9805859d585b7a8826017b772b3976a5 294 Gene3D G3DSA:3.90.550.10 1 293 8.6E-90 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_19985 7973e1c4be9f042b3aa3f0ac3658ef68 420 SUPERFAMILY SSF56059 112 321 7.88E-40 T 15-10-2018 C2I28_19985 7973e1c4be9f042b3aa3f0ac3658ef68 420 Gene3D G3DSA:3.30.470.20 106 420 3.2E-109 T 15-10-2018 C2I28_19985 7973e1c4be9f042b3aa3f0ac3658ef68 420 Gene3D G3DSA:3.40.50.20 1 102 1.6E-36 T 15-10-2018 C2I28_19985 7973e1c4be9f042b3aa3f0ac3658ef68 420 Pfam PF13535 ATP-grasp domain 145 296 3.8E-31 T 15-10-2018 C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 Pfam PF12368 Rhodanase C-terminal 224 290 1.7E-14 T 15-10-2018 IPR022111 Rhodanase, C-terminal C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 Pfam PF00581 Rhodanese-like domain 118 212 7.6E-13 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 269 40.532 T 15-10-2018 IPR020936 Uncharacterised protein family UPF0176 C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 SUPERFAMILY SSF52821 90 248 1.65E-37 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 SMART SM00450 117 218 3.2E-20 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 Gene3D G3DSA:3.40.250.10 104 253 8.7E-46 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_20095 bc6e1003b6ef129a0aac61eea3c1bb28 322 Gene3D G3DSA:3.30.70.100 1 99 4.0E-31 T 15-10-2018 C2I28_00540 14271101537d84bb558415a837733fe0 260 Gene3D G3DSA:3.40.630.30 120 248 1.2E-34 T 15-10-2018 C2I28_00540 14271101537d84bb558415a837733fe0 260 Pfam PF12746 GNAT acetyltransferase 21 257 1.9E-52 T 15-10-2018 IPR027365 GNAT acetyltransferase YdfB-like C2I28_00540 14271101537d84bb558415a837733fe0 260 SUPERFAMILY SSF55729 129 257 5.75E-13 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_07145 29ff2ca7c502ac6e02d19187ce53febf 84 SUPERFAMILY SSF101498 1 82 6.93E-17 T 15-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily C2I28_07145 29ff2ca7c502ac6e02d19187ce53febf 84 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 83 1.5E-13 T 15-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 C2I28_07145 29ff2ca7c502ac6e02d19187ce53febf 84 Pfam PF04316 Anti-sigma-28 factor, FlgM 31 80 7.0E-13 T 15-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 SUPERFAMILY SSF55874 445 590 3.14E-17 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 487 591 1.2E-6 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 Pfam PF06580 Histidine kinase 391 469 8.1E-23 T 15-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 Gene3D G3DSA:3.30.565.10 443 596 7.2E-17 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 SUPERFAMILY SSF158472 327 377 2.75E-7 T 15-10-2018 C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 Gene3D G3DSA:3.30.450.20 178 297 8.4E-7 T 15-10-2018 C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 SMART SM00304 326 378 2.9E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_11185 5bcbe33c8fc5830c01872452a154b351 606 Gene3D G3DSA:1.20.1480.50 298 382 1.3E-8 T 15-10-2018 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 SUPERFAMILY SSF48452 6 235 2.89E-20 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 Pfam PF14559 Tetratricopeptide repeat 165 229 1.9E-8 T 15-10-2018 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 Pfam PF13432 Tetratricopeptide repeat 27 76 0.0036 T 15-10-2018 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 SUPERFAMILY SSF48452 227 324 2.15E-5 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 SMART SM00028 189 222 2.0E-6 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 SMART SM00028 21 54 62.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 SMART SM00028 90 123 69.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 SMART SM00028 55 88 66.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 Gene3D G3DSA:1.25.40.10 4 137 1.8E-14 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_06895 cee896772d4c3735d3903c20918c52b1 500 Gene3D G3DSA:1.25.40.10 156 324 6.5E-19 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_14035 382973f0dae2fd26db1b3a5c054ddc04 291 SUPERFAMILY SSF74650 1 290 3.58E-50 T 15-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I28_14035 382973f0dae2fd26db1b3a5c054ddc04 291 Pfam PF01263 Aldose 1-epimerase 2 183 3.5E-25 T 15-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 C2I28_14035 382973f0dae2fd26db1b3a5c054ddc04 291 Gene3D G3DSA:2.70.98.10 1 290 5.6E-97 T 15-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 C2I28_10430 26f00adfd68fbc8e4c7219d898b2e50c 437 Pfam PF00324 Amino acid permease 15 398 5.4E-34 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_10430 26f00adfd68fbc8e4c7219d898b2e50c 437 PIRSF PIRSF006060 2 431 5.4E-65 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_10430 26f00adfd68fbc8e4c7219d898b2e50c 437 Gene3D G3DSA:1.20.1740.10 8 433 1.7E-70 T 15-10-2018 C2I28_12865 3a92b9e093b17ab7ab287385e84726d6 349 SUPERFAMILY SSF48371 218 322 1.92E-12 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_12865 3a92b9e093b17ab7ab287385e84726d6 349 Gene3D G3DSA:1.25.10.10 184 347 3.0E-10 T 15-10-2018 IPR011989 Armadillo-like helical C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 Gene3D G3DSA:1.10.287.130 251 331 6.5E-19 T 15-10-2018 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 SMART SM00387 375 487 3.6E-35 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 329 5.3E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 486 9.2E-21 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 1.1E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 1.1E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 1.1E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 1.1E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 SUPERFAMILY SSF47384 252 329 5.49E-17 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 SMART SM00388 265 331 7.4E-12 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 Gene3D G3DSA:3.30.565.10 336 489 6.8E-38 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 SUPERFAMILY SSF158472 192 241 8.24E-5 T 15-10-2018 C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 SUPERFAMILY SSF55874 321 485 1.01E-36 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_22620 bd03723883a97ac8eb058808c25e025b 489 Gene3D G3DSA:1.20.1480.50 154 249 2.9E-7 T 15-10-2018 C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 Pfam PF01546 Peptidase family M20/M25/M40 86 417 2.9E-32 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 SUPERFAMILY SSF55031 215 307 7.15E-8 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 Pfam PF07687 Peptidase dimerisation domain 188 309 2.6E-23 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 Gene3D G3DSA:3.30.70.360 191 325 3.0E-86 T 15-10-2018 C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 SUPERFAMILY SSF53187 8 420 5.47E-60 T 15-10-2018 C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 Gene3D G3DSA:3.40.630.10 37 420 3.0E-86 T 15-10-2018 C2I28_12600 2a35f02d5b75e5cc0549a80c3aa5e0fa 425 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 411 1.7E-115 T 15-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase C2I28_05560 ad6c81189f04aa4a600059dbe347f605 62 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 8.7E-22 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_05560 ad6c81189f04aa4a600059dbe347f605 62 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_05560 ad6c81189f04aa4a600059dbe347f605 62 Gene3D G3DSA:1.10.8.910 5 62 9.4E-30 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_05560 ad6c81189f04aa4a600059dbe347f605 62 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_24160 988b0ea6a0fca2e16dcde82b6a444398 189 Pfam PF05067 Manganese containing catalase 1 183 2.4E-77 T 15-10-2018 IPR007760 Manganese catalase C2I28_24160 988b0ea6a0fca2e16dcde82b6a444398 189 SUPERFAMILY SSF47240 1 186 8.33E-69 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_24160 988b0ea6a0fca2e16dcde82b6a444398 189 Gene3D G3DSA:1.20.1260.10 1 184 9.7E-65 T 15-10-2018 IPR012347 Ferritin-like C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 SMART SM00871 130 291 3.0E-37 T 15-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 Pfam PF14526 Integron-associated effector binding protein 134 290 5.4E-32 T 15-10-2018 IPR029441 Integron-associated effector binding protein C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 5.6E-6 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 5.6E-6 T 15-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 Gene3D G3DSA:1.10.10.60 58 111 1.2E-16 T 15-10-2018 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 Gene3D G3DSA:1.10.10.60 2 57 1.5E-17 T 15-10-2018 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 SUPERFAMILY SSF55136 130 292 6.28E-31 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 SUPERFAMILY SSF46689 6 55 1.7E-9 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 SUPERFAMILY SSF46689 57 107 2.64E-13 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 SMART SM00342 21 104 4.2E-29 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 Pfam PF12833 Helix-turn-helix domain 27 105 6.0E-22 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_16380 00b6159bb2a07cdd434604330f3fb40a 297 Gene3D G3DSA:3.20.80.10 130 296 1.1E-45 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_13260 ab1452cd62ac4250055a708cdb62729c 643 SUPERFAMILY SSF52540 97 417 6.25E-6 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Pfam PF01476 LysM domain 4 47 2.7E-13 T 15-10-2018 IPR018392 LysM domain C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Pfam PF01476 LysM domain 53 96 5.5E-12 T 15-10-2018 IPR018392 LysM domain C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 SUPERFAMILY SSF54106 51 96 1.83E-9 T 15-10-2018 C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Gene3D G3DSA:3.10.50.10 324 383 1.3E-111 T 15-10-2018 IPR029070 Chitinase insertion domain superfamily C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 SMART SM00257 52 96 4.7E-10 T 15-10-2018 IPR018392 LysM domain C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 SMART SM00257 3 47 8.2E-14 T 15-10-2018 IPR018392 LysM domain C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Pfam PF00704 Glycosyl hydrolases family 18 132 412 1.6E-24 T 15-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 SMART SM00636 104 412 7.2E-29 T 15-10-2018 IPR011583 Chitinase II GO:0008061 C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Gene3D G3DSA:3.10.350.10 51 105 5.1E-13 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Gene3D G3DSA:3.20.20.80 130 417 1.3E-111 T 15-10-2018 C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 Gene3D G3DSA:3.10.350.10 1 50 1.4E-13 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 SUPERFAMILY SSF51445 124 429 2.93E-45 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_08115 04ff3d8ae9e4f3f67b5bbdd2fc2bca7a 433 SUPERFAMILY SSF54106 2 47 1.11E-10 T 15-10-2018 C2I28_00410 f414a28bdfe79417fd91d784ec1fbf59 138 SMART SM00530 6 61 3.2E-17 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_00410 f414a28bdfe79417fd91d784ec1fbf59 138 SUPERFAMILY SSF47413 2 66 2.11E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_00410 f414a28bdfe79417fd91d784ec1fbf59 138 Gene3D G3DSA:1.10.260.40 1 64 8.7E-23 T 15-10-2018 C2I28_00410 f414a28bdfe79417fd91d784ec1fbf59 138 Pfam PF01381 Helix-turn-helix 7 61 2.8E-18 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 SUPERFAMILY SSF46785 2 73 2.53E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 Gene3D G3DSA:1.10.10.10 1 73 6.2E-31 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 Gene3D G3DSA:3.40.50.2020 74 273 2.7E-61 T 15-10-2018 C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 270 1.8E-126 T 15-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 3.5E-31 T 15-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 SUPERFAMILY SSF53271 94 256 1.7E-40 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 Pfam PF00156 Phosphoribosyl transferase domain 107 265 2.7E-24 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_08340 0ff462051d5413fb0bb793a460bcf525 273 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 1.0E-24 T 15-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 Pfam PF01584 CheW-like domain 18 152 2.1E-36 T 15-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 SUPERFAMILY SSF50341 7 153 8.5E-38 T 15-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 SMART SM00260 13 149 4.0E-36 T 15-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 Gene3D G3DSA:3.40.50.2300 159 300 1.9E-24 T 15-10-2018 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 Gene3D G3DSA:2.30.30.40 19 143 4.6E-37 T 15-10-2018 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 Pfam PF00072 Response regulator receiver domain 176 296 3.6E-22 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 SMART SM00448 174 296 1.3E-24 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 Gene3D G3DSA:2.40.50.180 34 149 4.6E-37 T 15-10-2018 C2I28_14620 9804d18c30abd1a759768f6c13441287 301 PIRSF PIRSF002867 1 301 1.5E-103 T 15-10-2018 IPR024181 Chemotaxis response regulator CheV C2I28_14620 9804d18c30abd1a759768f6c13441287 301 SUPERFAMILY SSF52172 171 298 6.69E-24 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_07635 d190f3956034a598067a1c7e5dd853db 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 405 5.7E-19 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_07635 d190f3956034a598067a1c7e5dd853db 411 Gene3D G3DSA:1.10.10.2840 278 411 7.5E-20 T 15-10-2018 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 312 421 4.6E-12 T 15-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 SUPERFAMILY SSF69189 304 398 4.12E-12 T 15-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 2.0E-14 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 2.0E-14 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 2.0E-14 T 15-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 SUPERFAMILY SSF56601 10 312 2.25E-76 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 287 2.8E-78 T 15-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 Gene3D G3DSA:3.40.710.10 29 312 4.2E-90 T 15-10-2018 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 SMART SM00936 312 421 1.8E-10 T 15-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_08080 5976f3d54c259a4c7ddee26cd78a84ab 451 Gene3D G3DSA:2.60.410.10 313 421 2.6E-15 T 15-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 C2I28_23570 a2970794acc9eaa8d553f029f3af1be1 334 Pfam PF11553 Protein of unknown function (DUF3231) 170 331 7.1E-41 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_23570 a2970794acc9eaa8d553f029f3af1be1 334 Pfam PF11553 Protein of unknown function (DUF3231) 5 159 6.4E-27 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 SUPERFAMILY SSF52151 4 309 3.4E-81 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 Gene3D G3DSA:3.40.366.10 5 286 5.0E-101 T 15-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 Gene3D G3DSA:3.30.70.250 124 197 5.0E-101 T 15-10-2018 C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 Pfam PF00698 Acyl transferase domain 6 288 5.0E-48 T 15-10-2018 IPR014043 Acyl transferase C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 PIRSF PIRSF000446 1 311 3.0E-121 T 15-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 3.1E-118 T 15-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 SUPERFAMILY SSF55048 129 193 4.05E-16 T 15-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding C2I28_02675 b89afe2dcff1ff5ebc701a7a016c4b7b 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 1.4E-52 T 15-10-2018 IPR020801 Polyketide synthase, acyl transferase domain C2I28_21940 aa6640bc92c89186d661a10122ede1ad 276 Gene3D G3DSA:1.10.3720.10 2 263 3.9E-59 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_21940 aa6640bc92c89186d661a10122ede1ad 276 SUPERFAMILY SSF161098 5 276 3.4E-66 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_21940 aa6640bc92c89186d661a10122ede1ad 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 267 1.4E-20 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_11635 8f175ab62207804de21e86013a956ad3 64 Pfam PF10815 ComZ 3 57 1.4E-31 T 15-10-2018 IPR024558 ComZ C2I28_11635 8f175ab62207804de21e86013a956ad3 64 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 1 56 4.0E-16 T 15-10-2018 IPR024558 ComZ C2I28_03995 e5f25d3087772876d30299baab25c7f8 274 ProDom PD123329 YQHG BH2818 1 259 2.0E-87 T 15-10-2018 IPR024562 Uncharacterised protein family YqhG C2I28_03995 e5f25d3087772876d30299baab25c7f8 274 Pfam PF11079 Bacterial protein YqhG of unknown function 1 259 1.6E-116 T 15-10-2018 IPR024562 Uncharacterised protein family YqhG C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 Gene3D G3DSA:3.60.15.10 119 355 2.5E-47 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 Pfam PF00753 Metallo-beta-lactamase superfamily 130 294 3.3E-13 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 SMART SM00450 7 109 1.1E-12 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 SMART SM00849 130 294 9.4E-27 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 SUPERFAMILY SSF52821 2 110 2.75E-18 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 Gene3D G3DSA:3.40.250.10 2 111 1.6E-18 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 Pfam PF00581 Rhodanese-like domain 7 105 6.9E-11 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24600 9c62d7b476ceaca445f0fe2c0d40623e 375 SUPERFAMILY SSF56281 124 370 1.12E-42 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 15-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 322 1.7E-152 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 Gene3D G3DSA:3.20.20.70 2 324 7.9E-151 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 SUPERFAMILY SSF51569 5 325 7.12E-144 T 15-10-2018 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 7.7E-60 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 7.7E-60 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 7.7E-60 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 7.7E-60 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 7.7E-60 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 7.7E-60 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 SMART SM01004 4 323 2.1E-237 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04960 029d7bc01ad84e496465058938e6b4e4 326 PIRSF PIRSF001415 1 326 8.6E-157 T 15-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 C2I28_04550 4e60c86aea3b855063efcc47089abcaa 588 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 579 2.3E-55 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_04550 4e60c86aea3b855063efcc47089abcaa 588 Gene3D G3DSA:3.90.1310.30 51 231 2.8E-10 T 15-10-2018 C2I28_04550 4e60c86aea3b855063efcc47089abcaa 588 Gene3D G3DSA:3.40.710.10 237 587 9.2E-73 T 15-10-2018 C2I28_04550 4e60c86aea3b855063efcc47089abcaa 588 SUPERFAMILY SSF56519 50 223 5.49E-15 T 15-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 C2I28_04550 4e60c86aea3b855063efcc47089abcaa 588 SUPERFAMILY SSF56601 188 581 5.97E-62 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_04510 f537d0270b7e40774e37eb37f4d76c23 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 1.8E-21 T 15-10-2018 IPR012655 Uncharacterised protein YrzI C2I28_04510 f537d0270b7e40774e37eb37f4d76c23 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 45 3.3E-16 T 15-10-2018 IPR012655 Uncharacterised protein YrzI C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 Gene3D G3DSA:3.30.465.40 12 241 1.1E-68 T 15-10-2018 C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 Gene3D G3DSA:1.10.45.10 424 463 1.5E-5 T 15-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 SUPERFAMILY SSF56176 12 222 7.01E-70 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 463 6.9E-60 T 15-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 Pfam PF01565 FAD binding domain 46 184 2.7E-40 T 15-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 SUPERFAMILY SSF55103 225 473 2.62E-63 T 15-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I28_22480 b217c9d7c6cf9af4da9599ee7de17bb3 483 Gene3D G3DSA:3.30.70.2740 343 423 3.6E-8 T 15-10-2018 C2I28_14435 54504f54d2c587a4460b3044d86d3712 233 SUPERFAMILY SSF51735 1 206 1.92E-37 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14435 54504f54d2c587a4460b3044d86d3712 233 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 112 6.9E-8 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_14435 54504f54d2c587a4460b3044d86d3712 233 Gene3D G3DSA:3.40.50.720 1 219 1.2E-53 T 15-10-2018 C2I28_24135 908508e26c8caccd9d038e7b33cf01cb 172 Pfam PF01872 RibD C-terminal domain 4 163 7.3E-16 T 15-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 C2I28_24135 908508e26c8caccd9d038e7b33cf01cb 172 SUPERFAMILY SSF53597 2 171 6.68E-34 T 15-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I28_24135 908508e26c8caccd9d038e7b33cf01cb 172 Gene3D G3DSA:3.40.430.10 1 172 2.8E-44 T 15-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 Gene3D G3DSA:3.10.580.10 1 136 1.6E-36 T 15-10-2018 C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 SUPERFAMILY SSF54631 1 130 4.17E-31 T 15-10-2018 C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 SMART SM00116 81 128 8.9E-12 T 15-10-2018 IPR000644 CBS domain C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 SMART SM00116 10 58 1.1E-11 T 15-10-2018 IPR000644 CBS domain C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 Pfam PF01842 ACT domain 139 181 3.8E-7 T 15-10-2018 IPR002912 ACT domain C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 Gene3D G3DSA:3.30.70.260 137 193 5.0E-6 T 15-10-2018 C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 SUPERFAMILY SSF55021 138 205 1.73E-8 T 15-10-2018 C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 Pfam PF00571 CBS domain 3 56 2.0E-13 T 15-10-2018 IPR000644 CBS domain C2I28_05620 1dd96d0ce4ef7a8deb1c1fafa9d63d80 213 Pfam PF00571 CBS domain 77 125 7.6E-11 T 15-10-2018 IPR000644 CBS domain C2I28_19485 6523a889898f622d2350b109f929d9d5 844 SMART SM00382 161 454 5.3E-4 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_19485 6523a889898f622d2350b109f929d9d5 844 SUPERFAMILY SSF52540 159 620 3.65E-41 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19485 6523a889898f622d2350b109f929d9d5 844 Pfam PF13087 AAA domain 390 574 6.7E-27 T 15-10-2018 C2I28_19485 6523a889898f622d2350b109f929d9d5 844 Gene3D G3DSA:3.40.50.300 403 614 1.1E-33 T 15-10-2018 C2I28_19485 6523a889898f622d2350b109f929d9d5 844 Gene3D G3DSA:3.40.50.300 110 389 1.9E-45 T 15-10-2018 C2I28_19485 6523a889898f622d2350b109f929d9d5 844 Pfam PF13086 AAA domain 149 363 1.2E-26 T 15-10-2018 C2I28_00675 6a66db1fd79f123aaf65271b60455609 399 Gene3D G3DSA:1.20.1250.20 5 379 6.0E-57 T 15-10-2018 C2I28_00675 6a66db1fd79f123aaf65271b60455609 399 SUPERFAMILY SSF103473 1 391 2.88E-65 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_00675 6a66db1fd79f123aaf65271b60455609 399 Pfam PF07690 Major Facilitator Superfamily 16 240 3.5E-31 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_00675 6a66db1fd79f123aaf65271b60455609 399 Pfam PF05977 Transmembrane secretion effector 273 392 2.6E-6 T 15-10-2018 IPR010290 Transmembrane secretion effector C2I28_23000 2b04bff5009e54f31ba54cbaafe88e2c 200 Pfam PF01738 Dienelactone hydrolase family 79 182 2.8E-10 T 15-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 C2I28_23000 2b04bff5009e54f31ba54cbaafe88e2c 200 Gene3D G3DSA:3.40.50.1820 1 198 2.2E-47 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_23000 2b04bff5009e54f31ba54cbaafe88e2c 200 SUPERFAMILY SSF53474 2 197 3.98E-53 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_12805 7ecd3004c0dacb2efed3e53205c8bef4 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 30.222 T 15-10-2018 IPR023064 D-ribose pyranase GO:0016872 C2I28_12805 7ecd3004c0dacb2efed3e53205c8bef4 129 Gene3D G3DSA:3.40.1650.10 8 125 1.1E-34 T 15-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 C2I28_12805 7ecd3004c0dacb2efed3e53205c8bef4 129 Pfam PF05025 RbsD / FucU transport protein family 1 128 1.9E-43 T 15-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 C2I28_12805 7ecd3004c0dacb2efed3e53205c8bef4 129 SUPERFAMILY SSF102546 1 129 7.32E-39 T 15-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 C2I28_20405 1129ef8aeb74caa3730c3add745d19f8 170 Pfam PF03167 Uracil DNA glycosylase superfamily 6 150 1.4E-23 T 15-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_20405 1129ef8aeb74caa3730c3add745d19f8 170 Gene3D G3DSA:3.40.470.10 4 169 3.3E-64 T 15-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_20405 1129ef8aeb74caa3730c3add745d19f8 170 SUPERFAMILY SSF52141 4 166 6.1E-42 T 15-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 C2I28_08860 9b6fabb3fb015a5c77b8cd567b7e2255 140 Pfam PF10730 Protein of unknown function (DUF2521) 2 140 1.6E-36 T 15-10-2018 IPR019667 Uncharacterised protein family YbaK C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 Gene3D G3DSA:3.40.50.2300 2 142 9.6E-37 T 15-10-2018 C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-30 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 SMART SM00448 2 115 1.3E-35 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 SUPERFAMILY SSF46785 169 239 6.76E-7 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 PIRSF PIRSF006171 1 228 2.5E-84 T 15-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 SUPERFAMILY SSF52172 2 137 5.83E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 Pfam PF08279 HTH domain 165 204 1.5E-4 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_09775 b3cfbc1e2be4b263a1a1eec0c6116c7b 241 Gene3D G3DSA:1.10.10.10 156 241 1.7E-5 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12630 8f1503ffae7041a39aa81bd281586219 185 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 8 185 1.4E-70 T 15-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 C2I28_12630 8f1503ffae7041a39aa81bd281586219 185 Pfam PF01380 SIS domain 33 155 7.7E-18 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_12630 8f1503ffae7041a39aa81bd281586219 185 Gene3D G3DSA:3.40.50.10490 1 185 4.4E-54 T 15-10-2018 C2I28_12630 8f1503ffae7041a39aa81bd281586219 185 SUPERFAMILY SSF53697 5 184 2.45E-38 T 15-10-2018 C2I28_17630 eaef41ac9aaea983de687aefe675cdc9 247 Gene3D G3DSA:3.40.50.10990 55 220 4.5E-51 T 15-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_17630 eaef41ac9aaea983de687aefe675cdc9 247 Pfam PF00925 GTP cyclohydrolase II 74 217 4.5E-44 T 15-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_17630 eaef41ac9aaea983de687aefe675cdc9 247 SUPERFAMILY SSF142695 74 220 3.53E-43 T 15-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 SUPERFAMILY SSF55486 10 586 3.05E-143 T 15-10-2018 C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 Gene3D G3DSA:1.20.140.70 30 185 2.4E-58 T 15-10-2018 C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 Pfam PF08439 Oligopeptidase F 120 189 1.5E-24 T 15-10-2018 IPR013647 Oligopeptidase F, N-terminal domain C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 Gene3D G3DSA:1.10.287.830 187 233 1.7E-22 T 15-10-2018 C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 13 601 6.8E-224 T 15-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 Gene3D G3DSA:1.10.1370.20 234 605 5.9E-148 T 15-10-2018 C2I28_11780 7b721c57008ccadeadaa51b33e02da8b 605 Pfam PF01432 Peptidase family M3 211 590 4.2E-83 T 15-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 C2I28_01500 5873a3bb5c4105b61ea9295a5df6050b 321 Gene3D G3DSA:1.20.1530.20 6 316 9.8E-59 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_01500 5873a3bb5c4105b61ea9295a5df6050b 321 Pfam PF01758 Sodium Bile acid symporter family 42 210 1.9E-16 T 15-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 C2I28_10300 5af32ade7110855b942fb2928358f43b 536 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 202 531 1.2E-26 T 15-10-2018 IPR024455 Phage capsid C2I28_10300 5af32ade7110855b942fb2928358f43b 536 Pfam PF04586 Caudovirus prohead serine protease 9 170 6.0E-40 T 15-10-2018 IPR006433 Prohead protease C2I28_10300 5af32ade7110855b942fb2928358f43b 536 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 21 165 6.2E-28 T 15-10-2018 IPR006433 Prohead protease C2I28_10300 5af32ade7110855b942fb2928358f43b 536 Pfam PF05065 Phage capsid family 269 532 4.4E-22 T 15-10-2018 IPR024455 Phage capsid C2I28_10300 5af32ade7110855b942fb2928358f43b 536 SUPERFAMILY SSF56563 261 532 4.18E-29 T 15-10-2018 C2I28_02375 92cffaf1fcbe27a8d246affc3985d2e0 185 Gene3D G3DSA:1.10.132.20 12 182 5.5E-71 T 15-10-2018 C2I28_02375 92cffaf1fcbe27a8d246affc3985d2e0 185 Pfam PF01765 Ribosome recycling factor 20 183 1.6E-66 T 15-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 C2I28_02375 92cffaf1fcbe27a8d246affc3985d2e0 185 Gene3D G3DSA:3.30.1360.40 31 105 5.5E-71 T 15-10-2018 C2I28_02375 92cffaf1fcbe27a8d246affc3985d2e0 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.378 T 15-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 C2I28_02375 92cffaf1fcbe27a8d246affc3985d2e0 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 8.4E-77 T 15-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 C2I28_02375 92cffaf1fcbe27a8d246affc3985d2e0 185 SUPERFAMILY SSF55194 4 183 1.96E-73 T 15-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 C2I28_11040 404381a5c8eb007b0fa4a45ec5ca5280 313 Gene3D G3DSA:1.10.3210.10 117 296 3.8E-8 T 15-10-2018 C2I28_11040 404381a5c8eb007b0fa4a45ec5ca5280 313 Pfam PF01966 HD domain 161 278 6.9E-11 T 15-10-2018 IPR006674 HD domain C2I28_11040 404381a5c8eb007b0fa4a45ec5ca5280 313 SMART SM00471 156 288 7.8E-5 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_11040 404381a5c8eb007b0fa4a45ec5ca5280 313 SUPERFAMILY SSF50249 31 92 6.43E-5 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_11040 404381a5c8eb007b0fa4a45ec5ca5280 313 SUPERFAMILY SSF109604 140 279 3.77E-10 T 15-10-2018 C2I28_11040 404381a5c8eb007b0fa4a45ec5ca5280 313 Gene3D G3DSA:2.40.50.140 22 104 1.8E-7 T 15-10-2018 C2I28_05455 1f2f88910c31d809998a473adc4039df 111 Pfam PF14034 Sporulation protein YtrH 10 107 8.0E-39 T 15-10-2018 IPR025689 Sporulation protein YtrH C2I28_24840 828a219b81f3d70083f08f2533cc29b2 211 Gene3D G3DSA:3.40.50.360 1 211 5.2E-57 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24840 828a219b81f3d70083f08f2533cc29b2 211 Pfam PF02525 Flavodoxin-like fold 3 203 1.7E-42 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_24840 828a219b81f3d70083f08f2533cc29b2 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 27.477 T 15-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I28_24840 828a219b81f3d70083f08f2533cc29b2 211 SUPERFAMILY SSF52218 1 211 7.21E-49 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_00400 f4e6172c75af860d7f0d81b71865d1b6 185 Gene3D G3DSA:2.160.10.10 1 185 6.8E-73 T 15-10-2018 C2I28_00400 f4e6172c75af860d7f0d81b71865d1b6 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 15-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I28_00400 f4e6172c75af860d7f0d81b71865d1b6 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 164 6.4E-10 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_00400 f4e6172c75af860d7f0d81b71865d1b6 185 SMART SM01266 5 59 1.8E-22 T 15-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 C2I28_00400 f4e6172c75af860d7f0d81b71865d1b6 185 SUPERFAMILY SSF51161 1 184 3.19E-54 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_00400 f4e6172c75af860d7f0d81b71865d1b6 185 Pfam PF12464 Maltose acetyltransferase 7 58 4.1E-17 T 15-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 SMART SM00866 95 233 1.1E-22 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 Gene3D G3DSA:1.10.10.10 3 77 1.2E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 SUPERFAMILY SSF46785 5 83 1.17E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.9E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.9E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 SUPERFAMILY SSF64288 62 239 3.93E-37 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 Pfam PF07702 UTRA domain 96 232 1.7E-27 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 Gene3D G3DSA:3.40.1410.10 78 239 2.2E-29 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 1.4E-20 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_02225 ed6250457da13bd5c0f085508a8f11df 241 SMART SM00345 14 73 2.1E-21 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13270 6132aec8c11646878defbe2e9c9971e0 224 Pfam PF13649 Methyltransferase domain 47 141 1.8E-21 T 15-10-2018 C2I28_13270 6132aec8c11646878defbe2e9c9971e0 224 SUPERFAMILY SSF53335 8 224 6.75E-37 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_05745 24089b8f4e5319ef8048f5cff875243a 184 SUPERFAMILY SSF55144 6 182 1.52E-32 T 15-10-2018 IPR009097 Cyclic phosphodiesterase C2I28_05745 24089b8f4e5319ef8048f5cff875243a 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 181 18.938 T 15-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 C2I28_05745 24089b8f4e5319ef8048f5cff875243a 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 6 181 2.4E-39 T 15-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 C2I28_05745 24089b8f4e5319ef8048f5cff875243a 184 Pfam PF13563 2'-5' RNA ligase superfamily 14 160 8.0E-17 T 15-10-2018 C2I28_05745 24089b8f4e5319ef8048f5cff875243a 184 Gene3D G3DSA:3.90.1140.10 1 182 2.9E-35 T 15-10-2018 C2I28_11075 f86b75f1ce9f051556c42a1ffd594fc8 198 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 3 186 50.153 T 15-10-2018 IPR023488 HTH-type transcriptional regulator Hpr C2I28_11075 f86b75f1ce9f051556c42a1ffd594fc8 198 Gene3D G3DSA:1.10.10.10 2 168 1.5E-47 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11075 f86b75f1ce9f051556c42a1ffd594fc8 198 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 15-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I28_11075 f86b75f1ce9f051556c42a1ffd594fc8 198 SMART SM00347 38 138 1.7E-16 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_11075 f86b75f1ce9f051556c42a1ffd594fc8 198 SUPERFAMILY SSF46785 20 131 1.26E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_11075 f86b75f1ce9f051556c42a1ffd594fc8 198 Pfam PF01047 MarR family 45 102 5.2E-14 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_23830 2d88dcdeca42a24b44fe42c7325099f1 377 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 345 376 1.9E-4 T 15-10-2018 C2I28_23830 2d88dcdeca42a24b44fe42c7325099f1 377 TIGRFAM TIGR04383 acidic_w_LPXTA: processed acidic surface protein 1 376 1.6E-78 T 15-10-2018 IPR030832 Processed acidic surface protein C2I28_14340 e47a9b1054dc35bb8dfea8fac955ff4b 79 Pfam PF09388 Spo0E like sporulation regulatory protein 13 54 1.7E-15 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_14340 e47a9b1054dc35bb8dfea8fac955ff4b 79 SUPERFAMILY SSF140500 10 59 1.44E-14 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_14340 e47a9b1054dc35bb8dfea8fac955ff4b 79 Gene3D G3DSA:1.20.58.990 9 66 1.9E-11 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_08840 5a9a30fdfce366275b0d9bd473876717 265 Pfam PF02361 Cobalt transport protein 14 237 4.0E-57 T 15-10-2018 IPR003339 ABC/ECF transporter, transmembrane component C2I28_08840 5a9a30fdfce366275b0d9bd473876717 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 37.866 T 15-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 Gene3D G3DSA:3.40.50.720 100 289 6.3E-122 T 15-10-2018 C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 15-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 15-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 321 5.6E-33 T 15-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 SUPERFAMILY SSF51735 106 290 1.59E-61 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 SUPERFAMILY SSF52283 3 137 2.27E-36 T 15-10-2018 C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 Gene3D G3DSA:3.40.50.720 6 315 6.3E-122 T 15-10-2018 C2I28_06440 13d8dccbe90b641d0d021f11972c4600 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 289 5.8E-66 T 15-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 C2I28_05615 6e8066728abf6d3092bedef90c45bbb0 210 Gene3D G3DSA:3.40.630.30 1 210 5.3E-89 T 15-10-2018 C2I28_05615 6e8066728abf6d3092bedef90c45bbb0 210 PIRSF PIRSF021278 2 210 1.7E-90 T 15-10-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 C2I28_26920 2e7601e99706c4a936e8def73d1988c2 1776 Pfam PF12846 AAA-like domain 1438 1702 2.0E-8 T 15-10-2018 C2I28_26920 2e7601e99706c4a936e8def73d1988c2 1776 SUPERFAMILY SSF52540 1410 1771 8.27E-32 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 SUPERFAMILY SSF46785 9 84 3.44E-24 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 1.3E-14 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 2.6E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 2.6E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 2.6E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 2.6E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 Gene3D G3DSA:1.10.10.10 1 94 2.7E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17565 16719cd6ea25c2b2f1504e900cc30676 116 SMART SM00418 14 90 1.4E-26 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_17020 c04e1c453058628e2eb24cb6f9891069 110 Pfam PF08863 YolD-like protein 14 108 2.1E-18 T 15-10-2018 IPR014962 YolD-like protein C2I28_11845 02c5ab34f04627b6b546f2afb480a597 170 Pfam PF14153 Spore coat protein CotO 61 167 4.1E-17 T 15-10-2018 IPR025439 Spore coat protein CotO C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 299 2.7E-17 T 15-10-2018 IPR020801 Polyketide synthase, acyl transferase domain C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 Gene3D G3DSA:3.40.366.10 4 279 1.3E-69 T 15-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 PIRSF PIRSF000446 1 304 8.0E-70 T 15-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 SUPERFAMILY SSF52151 3 290 1.26E-52 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 Pfam PF00698 Acyl transferase domain 5 293 1.1E-24 T 15-10-2018 IPR014043 Acyl transferase C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 SUPERFAMILY SSF55048 122 190 6.8E-11 T 15-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding C2I28_12155 e05fd7ad06bed97ee4a6a154b9c8e577 308 Gene3D G3DSA:3.30.70.250 121 191 1.3E-69 T 15-10-2018 C2I28_10860 fefb15cf22a32a96c35eef473de4970a 314 Gene3D G3DSA:3.90.245.10 3 313 6.0E-101 T 15-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I28_10860 fefb15cf22a32a96c35eef473de4970a 314 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 301 9.4E-46 T 15-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain C2I28_10860 fefb15cf22a32a96c35eef473de4970a 314 SUPERFAMILY SSF53590 1 309 2.09E-81 T 15-10-2018 IPR036452 Ribonucleoside hydrolase-like C2I28_11390 e9bb280bb512fb8d808142fd41404afb 143 Pfam PF10970 Spore germination protein GerPE 5 124 3.5E-37 T 15-10-2018 IPR024496 Spore germination protein GerPE C2I28_11390 e9bb280bb512fb8d808142fd41404afb 143 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 6 117 1.0E-18 T 15-10-2018 IPR024496 Spore germination protein GerPE C2I28_24915 52b27fbc24a32998619c972d0362de89 642 SUPERFAMILY SSF56300 191 558 2.65E-9 T 15-10-2018 C2I28_24915 52b27fbc24a32998619c972d0362de89 642 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 2 642 38.864 T 15-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I28_24915 52b27fbc24a32998619c972d0362de89 642 PIRSF PIRSF000906 1 642 0.0 T 15-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I28_24915 52b27fbc24a32998619c972d0362de89 642 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 4 639 4.2E-287 T 15-10-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 C2I28_18735 409b1cefa3bb5f35e949a6d0c40f648e 296 Pfam PF02567 Phenazine biosynthesis-like protein 9 290 2.2E-75 T 15-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I28_18735 409b1cefa3bb5f35e949a6d0c40f648e 296 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 293 8.7E-94 T 15-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I28_18735 409b1cefa3bb5f35e949a6d0c40f648e 296 PIRSF PIRSF016184 1 295 5.8E-82 T 15-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I28_18735 409b1cefa3bb5f35e949a6d0c40f648e 296 SUPERFAMILY SSF54506 6 292 2.83E-63 T 15-10-2018 C2I28_18735 409b1cefa3bb5f35e949a6d0c40f648e 296 Gene3D G3DSA:3.10.310.10 123 284 8.1E-81 T 15-10-2018 C2I28_18735 409b1cefa3bb5f35e949a6d0c40f648e 296 Gene3D G3DSA:3.10.310.10 7 285 8.1E-81 T 15-10-2018 C2I28_06600 1d35345cfcd3030be685e446e2dcc6d7 49 Pfam PF14115 YuzL-like protein 3 43 6.3E-19 T 15-10-2018 IPR025625 YuzL-like protein C2I28_14880 9a9b6fbdc55134dc30322d007f56c40f 93 Gene3D G3DSA:1.10.287.750 4 93 1.1E-37 T 15-10-2018 IPR036270 UPF0358 superfamily C2I28_14880 9a9b6fbdc55134dc30322d007f56c40f 93 Pfam PF07408 Protein of unknown function (DUF1507) 9 91 5.4E-42 T 15-10-2018 IPR009983 Uncharacterised protein family UPF0358 C2I28_14880 9a9b6fbdc55134dc30322d007f56c40f 93 SUPERFAMILY SSF140404 5 84 2.75E-37 T 15-10-2018 IPR036270 UPF0358 superfamily C2I28_14880 9a9b6fbdc55134dc30322d007f56c40f 93 Hamap MF_01560 UPF0358 protein . 3 93 27.452 T 15-10-2018 IPR009983 Uncharacterised protein family UPF0358 C2I28_10715 ff4ddbc572e82840491a41fe502d0fe4 256 Gene3D G3DSA:3.20.20.140 2 255 1.2E-48 T 15-10-2018 C2I28_10715 ff4ddbc572e82840491a41fe502d0fe4 256 Pfam PF01026 TatD related DNase 5 253 4.3E-39 T 15-10-2018 IPR001130 TatD family GO:0016788 C2I28_10715 ff4ddbc572e82840491a41fe502d0fe4 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 15-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 C2I28_10715 ff4ddbc572e82840491a41fe502d0fe4 256 PIRSF PIRSF005902 1 256 4.5E-45 T 15-10-2018 IPR001130 TatD family GO:0016788 C2I28_10715 ff4ddbc572e82840491a41fe502d0fe4 256 SUPERFAMILY SSF51556 4 254 4.98E-46 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_18750 6e3cbc95f1d601e53d18c3fd3b88395a 255 Gene3D G3DSA:1.10.10.10 1 104 6.0E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18750 6e3cbc95f1d601e53d18c3fd3b88395a 255 SUPERFAMILY SSF46785 2 95 1.51E-10 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18750 6e3cbc95f1d601e53d18c3fd3b88395a 255 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 71 7.1E-22 T 15-10-2018 IPR002831 Transcription regulator TrmB, N-terminal C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 PIRSF PIRSF002939 1 216 1.6E-109 T 15-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 1.7E-27 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 SUPERFAMILY SSF88946 12 105 6.15E-24 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 5.7E-112 T 15-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 Pfam PF08281 Sigma-70, region 4 159 205 2.1E-10 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 SMART SM00421 160 209 0.0054 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 Pfam PF04542 Sigma-70 region 2 36 105 1.5E-14 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_08600 1cb07e03861115173c82b2c3257b12e5 216 SUPERFAMILY SSF88659 123 209 9.15E-12 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_08390 9e44a8edaa9fe6ad621f1e47c08a7801 534 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 362 508 5.6E-27 T 15-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I28_08390 9e44a8edaa9fe6ad621f1e47c08a7801 534 PIRSF PIRSF038958 2 525 3.0E-84 T 15-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I28_08390 9e44a8edaa9fe6ad621f1e47c08a7801 534 Pfam PF01943 Polysaccharide biosynthesis protein 12 310 1.4E-34 T 15-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 SMART SM00382 349 518 4.0E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 SMART SM00382 28 236 5.0E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 Pfam PF12848 ABC transporter 230 315 1.4E-21 T 15-10-2018 IPR032781 ABC-transporter extension domain C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 Gene3D G3DSA:3.40.50.300 289 515 2.3E-43 T 15-10-2018 C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 SUPERFAMILY SSF52540 5 246 2.32E-51 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 SUPERFAMILY SSF52540 307 507 1.75E-35 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 Pfam PF00005 ABC transporter 341 469 9.2E-24 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 Gene3D G3DSA:3.40.50.300 2 285 1.8E-67 T 15-10-2018 C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 Pfam PF00005 ABC transporter 20 191 1.0E-26 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_09875 72f79d6d8aa582cdccf1e9a8d18f4ae7 518 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_00130 db54098aec81921a087c3dc88d539fd5 500 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 45 488 2.2E-154 T 15-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I28_00130 db54098aec81921a087c3dc88d539fd5 500 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 488 9.8E-187 T 15-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I28_00130 db54098aec81921a087c3dc88d539fd5 500 ProSitePatterns PS01303 BCCT family of transporters signature. 309 318 - T 15-10-2018 IPR018093 BCCT transporter, conserved site C2I28_21485 93d237b06cf57d2c415a139b685e2e2f 152 Pfam PF04634 Protein of unknown function, DUF600 5 148 9.0E-47 T 15-10-2018 IPR006728 Protein of unknown function DUF600 C2I28_21485 93d237b06cf57d2c415a139b685e2e2f 152 SUPERFAMILY SSF160424 1 151 8.24E-47 T 15-10-2018 IPR036170 Probable antitoxin YezG superfamily C2I28_21485 93d237b06cf57d2c415a139b685e2e2f 152 Gene3D G3DSA:3.30.500.20 1 116 9.1E-42 T 15-10-2018 C2I28_21485 93d237b06cf57d2c415a139b685e2e2f 152 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 2 150 1.1E-35 T 15-10-2018 IPR006728 Protein of unknown function DUF600 C2I28_07960 9e73be44bf299314a8af06d20f60d13f 206 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 42 181 1.6E-67 T 15-10-2018 IPR009665 Protein of unknown function DUF1256 C2I28_07960 9e73be44bf299314a8af06d20f60d13f 206 SUPERFAMILY SSF53163 13 193 7.06E-52 T 15-10-2018 IPR023430 Peptidase HybD-like domain superfamily C2I28_07960 9e73be44bf299314a8af06d20f60d13f 206 Pfam PF06866 Protein of unknown function (DUF1256) 17 179 3.0E-65 T 15-10-2018 IPR009665 Protein of unknown function DUF1256 C2I28_14415 014af9950c7a1f8e896b313ad0e3bff0 221 SUPERFAMILY SSF52402 4 211 2.87E-66 T 15-10-2018 C2I28_14415 014af9950c7a1f8e896b313ad0e3bff0 221 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 205 6.6E-84 T 15-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I28_14415 014af9950c7a1f8e896b313ad0e3bff0 221 Pfam PF06508 Queuosine biosynthesis protein QueC 6 212 2.6E-85 T 15-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I28_14415 014af9950c7a1f8e896b313ad0e3bff0 221 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 218 51.364 T 15-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I28_14415 014af9950c7a1f8e896b313ad0e3bff0 221 Gene3D G3DSA:3.40.50.620 3 218 4.0E-74 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_14415 014af9950c7a1f8e896b313ad0e3bff0 221 PIRSF PIRSF006293 3 219 1.7E-79 T 15-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 SUPERFAMILY SSF90123 27 336 5.36E-64 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 Pfam PF00664 ABC transporter transmembrane region 42 309 3.0E-39 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 Gene3D G3DSA:3.40.50.300 346 600 1.2E-92 T 15-10-2018 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 Gene3D G3DSA:1.20.1560.10 4 340 1.4E-64 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 SMART SM00382 380 566 1.3E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 Pfam PF00005 ABC transporter 372 520 2.7E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_19000 00332296dce63a5eeede43c21b3ffbd1 603 SUPERFAMILY SSF52540 347 590 2.66E-91 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_19780 e546094eb7508022bf38253320bc6fad 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-7 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19780 e546094eb7508022bf38253320bc6fad 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-7 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19780 e546094eb7508022bf38253320bc6fad 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-7 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19780 e546094eb7508022bf38253320bc6fad 303 Gene3D G3DSA:1.10.10.10 1 91 6.0E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_19780 e546094eb7508022bf38253320bc6fad 303 SUPERFAMILY SSF46785 1 84 7.62E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_19780 e546094eb7508022bf38253320bc6fad 303 SUPERFAMILY SSF53850 90 294 1.19E-38 T 15-10-2018 C2I28_19780 e546094eb7508022bf38253320bc6fad 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.8E-20 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_19780 e546094eb7508022bf38253320bc6fad 303 Gene3D G3DSA:3.40.190.290 92 300 6.7E-48 T 15-10-2018 C2I28_19780 e546094eb7508022bf38253320bc6fad 303 Pfam PF03466 LysR substrate binding domain 89 293 2.7E-43 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_11010 3eba15ab0f21f4a9a38cf23d9c46551a 267 Gene3D G3DSA:3.90.226.10 1 196 1.8E-51 T 15-10-2018 C2I28_11010 3eba15ab0f21f4a9a38cf23d9c46551a 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 4.9E-48 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_11010 3eba15ab0f21f4a9a38cf23d9c46551a 267 Gene3D G3DSA:1.10.12.10 203 259 1.1E-17 T 15-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I28_11010 3eba15ab0f21f4a9a38cf23d9c46551a 267 SUPERFAMILY SSF52096 8 260 1.37E-62 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 Gene3D G3DSA:3.30.450.20 52 161 1.4E-34 T 15-10-2018 C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 PIRSF PIRSF026583 1 657 1.1E-275 T 15-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 Gene3D G3DSA:3.10.310.30 539 653 1.9E-10 T 15-10-2018 C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 SMART SM00267 132 299 1.3E-6 T 15-10-2018 IPR000160 GGDEF domain C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 Pfam PF01368 DHH family 339 496 5.8E-22 T 15-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 SUPERFAMILY SSF64182 339 642 1.29E-67 T 15-10-2018 IPR038763 DHH phosphoesterase superfamily C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 Pfam PF02272 DHHA1 domain 518 647 1.4E-13 T 15-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I28_07915 6e0ff39a3c13f9414d39c1032fc34699 657 Gene3D G3DSA:3.90.1640.10 322 538 7.5E-53 T 15-10-2018 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 6 430 2.3E-222 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 2.9E-110 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17570 e894bd7f78ffcf7251ab9edf26fb036d 432 Pfam PF02040 Arsenical pump membrane protein 6 428 1.8E-225 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 1.5E-21 T 15-10-2018 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 1.5E-21 T 15-10-2018 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.5E-21 T 15-10-2018 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.5E-21 T 15-10-2018 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 Pfam PF01494 FAD binding domain 5 344 2.0E-33 T 15-10-2018 IPR002938 FAD-binding domain GO:0071949 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 SUPERFAMILY SSF51905 4 350 1.49E-48 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 Gene3D G3DSA:3.30.9.50 75 270 1.4E-54 T 15-10-2018 C2I28_19015 e6b5a0ec9fd8124d241f3435f97557b4 373 Gene3D G3DSA:3.50.50.60 6 329 1.4E-54 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 Pfam PF07729 FCD domain 83 201 2.5E-12 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 1.9E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 SUPERFAMILY SSF48008 82 198 2.38E-11 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 Gene3D G3DSA:1.10.10.10 8 75 2.9E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 SUPERFAMILY SSF46785 10 77 1.08E-18 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 SMART SM00345 15 73 2.6E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_18055 8f603b5a2046b711c8426a4dfaeb5bba 217 Gene3D G3DSA:1.20.120.530 81 209 1.5E-14 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 1.7E-26 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 58 77 1.7E-26 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 140 151 1.7E-26 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 280 303 1.7E-26 T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 13 315 7.4E-133 T 15-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 12 316 82.135 T 15-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 Gene3D G3DSA:3.40.50.1370 143 311 9.3E-127 T 15-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 13 153 4.9E-54 T 15-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 56 70 4.0E-30 T 15-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 294 305 4.0E-30 T 15-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 129 143 4.0E-30 T 15-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 232 242 4.0E-30 T 15-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 89 102 4.0E-30 T 15-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 313 3.0E-60 T 15-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 SUPERFAMILY SSF53671 9 316 1.07E-112 T 15-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 Gene3D G3DSA:3.40.50.1370 13 142 9.3E-127 T 15-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 C2I28_11575 1967cb49de15fbe21b37a532300f4a12 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 58 65 - T 15-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 Gene3D G3DSA:1.10.10.10 4 74 8.5E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 Pfam PF01614 Bacterial transcriptional regulator 121 245 4.1E-32 T 15-10-2018 IPR014757 Transcription regulator IclR, C-terminal C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 SUPERFAMILY SSF55781 61 250 1.24E-45 T 15-10-2018 C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 SMART SM00346 5 93 7.2E-25 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 SUPERFAMILY SSF46785 6 77 3.55E-14 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 Pfam PF09339 IclR helix-turn-helix domain 7 56 1.1E-10 T 15-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 C2I28_20420 c31595b4aa5de14800e34fa5c7da031d 254 Gene3D G3DSA:3.30.450.40 75 253 1.5E-52 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_10495 c3eec8cfd2e14e55f0ed77641711e6a6 337 Gene3D G3DSA:2.30.30.40 28 143 3.3E-42 T 15-10-2018 C2I28_10495 c3eec8cfd2e14e55f0ed77641711e6a6 337 SUPERFAMILY SSF54001 214 336 2.6E-39 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_10495 c3eec8cfd2e14e55f0ed77641711e6a6 337 Gene3D G3DSA:3.90.1720.10 214 337 2.6E-39 T 15-10-2018 C2I28_10495 c3eec8cfd2e14e55f0ed77641711e6a6 337 Pfam PF00877 NlpC/P60 family 229 334 1.8E-25 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_10495 c3eec8cfd2e14e55f0ed77641711e6a6 337 Gene3D G3DSA:2.30.30.40 144 211 1.1E-31 T 15-10-2018 C2I28_04665 f58740922d3c1bc32458311f3b5a20c6 294 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 7 289 4.3E-92 T 15-10-2018 IPR011862 Phosphate binding protein GO:0042301 C2I28_04665 f58740922d3c1bc32458311f3b5a20c6 294 Gene3D G3DSA:3.40.190.10 119 246 6.1E-82 T 15-10-2018 C2I28_04665 f58740922d3c1bc32458311f3b5a20c6 294 Pfam PF12849 PBP superfamily domain 37 272 2.8E-40 T 15-10-2018 IPR024370 PBP domain C2I28_04665 f58740922d3c1bc32458311f3b5a20c6 294 Gene3D G3DSA:3.40.190.10 45 288 6.1E-82 T 15-10-2018 C2I28_04665 f58740922d3c1bc32458311f3b5a20c6 294 SUPERFAMILY SSF53850 42 290 3.42E-72 T 15-10-2018 C2I28_10625 a376505f0577de6e136231146c5e8241 262 Pfam PF04962 KduI/IolB family 14 251 1.4E-62 T 15-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 C2I28_10625 a376505f0577de6e136231146c5e8241 262 PIRSF PIRSF036628 1 257 1.5E-85 T 15-10-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 C2I28_10625 a376505f0577de6e136231146c5e8241 262 Gene3D G3DSA:2.60.120.10 119 257 1.2E-44 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_10625 a376505f0577de6e136231146c5e8241 262 SUPERFAMILY SSF51182 2 239 1.9E-46 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_10625 a376505f0577de6e136231146c5e8241 262 Gene3D G3DSA:2.60.120.10 16 118 1.7E-11 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_07045 1ab6587a25ea221f52288a49bb1e7110 72 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 48 1.6E-17 T 15-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I28_07045 1ab6587a25ea221f52288a49bb1e7110 72 Pfam PF02416 mttA/Hcf106 family 5 55 7.3E-21 T 15-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 C2I28_07045 1ab6587a25ea221f52288a49bb1e7110 72 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 71 16.803 T 15-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 C2I28_07045 1ab6587a25ea221f52288a49bb1e7110 72 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 4.5E-5 T 15-10-2018 C2I28_07045 1ab6587a25ea221f52288a49bb1e7110 72 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 4.5E-5 T 15-10-2018 C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 SUPERFAMILY SSF50129 1 173 6.7E-36 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 SMART SM00829 10 342 9.4E-9 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 Gene3D G3DSA:3.40.50.720 156 315 1.4E-96 T 15-10-2018 C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 137 1.5E-16 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 Pfam PF00107 Zinc-binding dehydrogenase 180 306 1.7E-26 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 Gene3D G3DSA:3.90.180.10 7 340 1.4E-96 T 15-10-2018 C2I28_25935 b01a596ebe32029018f51a239db7bd60 346 SUPERFAMILY SSF51735 146 320 7.89E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 Gene3D G3DSA:3.20.20.120 118 346 3.4E-132 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 SUPERFAMILY SSF51604 114 359 2.49E-62 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 125 3.4E-19 T 15-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 Pfam PF13378 Enolase C-terminal domain-like 145 353 6.7E-43 T 15-10-2018 IPR029065 Enolase C-terminal domain-like C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 SMART SM00922 142 234 2.0E-18 T 15-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 Gene3D G3DSA:3.30.390.10 8 357 3.4E-132 T 15-10-2018 IPR029017 Enolase-like, N-terminal C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 44.825 T 15-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 332 3.2E-125 T 15-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 C2I28_05985 d42c832b06fbfc1f2c0a34400869d857 367 SUPERFAMILY SSF54826 1 126 5.63E-37 T 15-10-2018 C2I28_21885 9cc911e5582315e1548b8014df9fa8cc 155 Pfam PF09406 Protein of unknown function (DUF2004) 61 152 2.6E-16 T 15-10-2018 IPR018546 Protein of unknown function DUF2004 C2I28_01180 64666155e5e69141b0045628f13f91c6 121 Gene3D G3DSA:2.60.120.10 7 105 2.7E-5 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_01180 64666155e5e69141b0045628f13f91c6 121 SUPERFAMILY SSF51182 16 88 7.12E-5 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_10905 af2f64323c89694072b44a992c537ce7 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.0E-18 T 15-10-2018 IPR010035 ThiS, thiamine-biosynthesis C2I28_10905 af2f64323c89694072b44a992c537ce7 67 Gene3D G3DSA:3.10.20.30 1 67 2.3E-19 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_10905 af2f64323c89694072b44a992c537ce7 67 SUPERFAMILY SSF54285 3 66 7.2E-16 T 15-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp C2I28_10905 af2f64323c89694072b44a992c537ce7 67 Pfam PF02597 ThiS family 10 67 9.7E-11 T 15-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 C2I28_13755 277e9ba21726e6469f6bc2920b0e852b 908 SUPERFAMILY SSF53756 679 832 2.35E-7 T 15-10-2018 C2I28_13755 277e9ba21726e6469f6bc2920b0e852b 908 Gene3D G3DSA:3.90.550.10 5 203 6.2E-53 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13755 277e9ba21726e6469f6bc2920b0e852b 908 SUPERFAMILY SSF53448 5 225 1.27E-55 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13755 277e9ba21726e6469f6bc2920b0e852b 908 Pfam PF00535 Glycosyl transferase family 2 7 126 1.2E-36 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_13755 277e9ba21726e6469f6bc2920b0e852b 908 Gene3D G3DSA:3.40.50.12580 710 891 4.8E-29 T 15-10-2018 C2I28_13755 277e9ba21726e6469f6bc2920b0e852b 908 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 552 897 1.2E-37 T 15-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 C2I28_22140 291877fc8bcdff636802a291bb67844d 195 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 194 19.834 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_22140 291877fc8bcdff636802a291bb67844d 195 SMART SM01207 11 186 1.6E-75 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_22140 291877fc8bcdff636802a291bb67844d 195 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 194 7.5E-56 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_22140 291877fc8bcdff636802a291bb67844d 195 Pfam PF02660 Glycerol-3-phosphate acyltransferase 12 185 2.9E-50 T 15-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 SUPERFAMILY SSF52172 2 125 8.25E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 SUPERFAMILY SSF46894 132 231 1.13E-30 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 Pfam PF00072 Response regulator receiver domain 5 115 1.4E-26 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 Gene3D G3DSA:3.40.50.2300 1 122 1.2E-35 T 15-10-2018 C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 1.9E-26 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 SMART SM00448 3 114 2.1E-39 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 Gene3D G3DSA:1.10.10.10 132 241 4.4E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06695 4bda164a201012ce3e42bb9e2a9fa186 241 SMART SM00862 155 230 1.6E-24 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_20660 9bb9127d10d7e4bb756d7c51d8b975c5 314 Gene3D G3DSA:3.40.50.1820 1 311 7.4E-54 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_20660 9bb9127d10d7e4bb756d7c51d8b975c5 314 SUPERFAMILY SSF53474 6 304 1.59E-35 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_20660 9bb9127d10d7e4bb756d7c51d8b975c5 314 Pfam PF12146 Serine aminopeptidase, S33 26 290 6.6E-56 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_23130 ed92d67dcf92e4f0851d45439760f5c9 285 Pfam PF02153 Prephenate dehydrogenase 17 273 2.2E-75 T 15-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 C2I28_23130 ed92d67dcf92e4f0851d45439760f5c9 285 Gene3D G3DSA:1.10.3660.10 178 284 7.3E-36 T 15-10-2018 C2I28_23130 ed92d67dcf92e4f0851d45439760f5c9 285 Gene3D G3DSA:3.40.50.720 1 177 6.9E-49 T 15-10-2018 C2I28_23130 ed92d67dcf92e4f0851d45439760f5c9 285 SUPERFAMILY SSF48179 174 283 2.61E-34 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_23130 ed92d67dcf92e4f0851d45439760f5c9 285 SUPERFAMILY SSF51735 4 169 1.39E-43 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_01385 ebda6582e302b5b50abf0d5a53e9ebc4 239 Pfam PF05908 Poly-gamma-glutamate hydrolase 32 221 1.6E-63 T 15-10-2018 IPR008585 Poly-gamma-glutamate hydrolase C2I28_01385 ebda6582e302b5b50abf0d5a53e9ebc4 239 Gene3D G3DSA:3.40.630.100 26 238 6.6E-73 T 15-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 PIRSF PIRSF001586 1 223 3.5E-91 T 15-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 Gene3D G3DSA:3.40.50.880 1 221 7.3E-75 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 SMART SM01211 1 220 2.8E-137 T 15-10-2018 C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 205 5.3E-48 T 15-10-2018 C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 45.77 T 15-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 SUPERFAMILY SSF52317 2 220 7.37E-79 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09450 778d42479062d83f89ccea0edc04b48d 228 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 8.9E-97 T 15-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 1.9E-25 T 15-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 SUPERFAMILY SSF47979 63 128 6.67E-18 T 15-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 SMART SM00529 24 123 1.0E-43 T 15-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 123 1.3E-17 T 15-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 Gene3D G3DSA:1.10.60.10 74 142 9.1E-32 T 15-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 Gene3D G3DSA:1.10.10.10 2 73 7.1E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 SUPERFAMILY SSF46785 3 62 1.63E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_03955 01b08fe220fd04dbb63734cef0135291 143 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 45.06 T 15-10-2018 IPR022897 HTH-type transcription regulator MntR C2I28_13310 357a280682c8f36bffc2f0be806f546c 294 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 284 1.3E-48 T 15-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 C2I28_13310 357a280682c8f36bffc2f0be806f546c 294 Gene3D G3DSA:3.90.850.10 81 293 1.5E-59 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_13310 357a280682c8f36bffc2f0be806f546c 294 SUPERFAMILY SSF56529 79 285 2.75E-52 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 Pfam PF01016 Ribosomal L27 protein 11 90 4.4E-34 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 43 57 - T 15-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 10 90 2.4E-40 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 Gene3D G3DSA:2.40.50.100 29 94 5.2E-26 T 15-10-2018 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 PRINTS PR00063 Ribosomal protein L27 signature 13 37 1.3E-38 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 PRINTS PR00063 Ribosomal protein L27 signature 38 62 1.3E-38 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 PRINTS PR00063 Ribosomal protein L27 signature 63 87 1.3E-38 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 37 78 7.0E-16 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 10 93 27.04 T 15-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04845 46a41cdabb7ba21066898e376c897c6d 97 SUPERFAMILY SSF110324 11 92 1.19E-31 T 15-10-2018 C2I28_12835 9868c7ee366ae44a9e9ba603fa52fcda 425 SUPERFAMILY SSF53850 33 421 1.19E-71 T 15-10-2018 C2I28_12835 9868c7ee366ae44a9e9ba603fa52fcda 425 Gene3D G3DSA:3.40.190.10 54 353 1.4E-90 T 15-10-2018 C2I28_12835 9868c7ee366ae44a9e9ba603fa52fcda 425 Pfam PF13416 Bacterial extracellular solute-binding protein 51 359 3.2E-43 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_12835 9868c7ee366ae44a9e9ba603fa52fcda 425 Gene3D G3DSA:3.40.190.10 149 407 1.4E-90 T 15-10-2018 C2I28_24505 a9b981d4bd4b4b0ac6e0c9fb1c7cbe10 462 Pfam PF12146 Serine aminopeptidase, S33 211 424 2.5E-10 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_24505 a9b981d4bd4b4b0ac6e0c9fb1c7cbe10 462 Pfam PF13026 Protein of unknown function (DUF3887) 48 135 1.3E-10 T 15-10-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 C2I28_24505 a9b981d4bd4b4b0ac6e0c9fb1c7cbe10 462 SUPERFAMILY SSF53474 150 428 6.08E-34 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_24505 a9b981d4bd4b4b0ac6e0c9fb1c7cbe10 462 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 256 286 - T 15-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 C2I28_24505 a9b981d4bd4b4b0ac6e0c9fb1c7cbe10 462 Gene3D G3DSA:3.40.50.1820 170 446 1.8E-38 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_13950 b872243a77f77b06c1571b949197d4af 241 SUPERFAMILY SSF64288 61 240 1.44E-57 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_13950 b872243a77f77b06c1571b949197d4af 241 Gene3D G3DSA:3.40.1410.10 77 241 2.1E-57 T 15-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily C2I28_13950 b872243a77f77b06c1571b949197d4af 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.9E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13950 b872243a77f77b06c1571b949197d4af 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.9E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13950 b872243a77f77b06c1571b949197d4af 241 SMART SM00345 14 73 1.2E-23 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13950 b872243a77f77b06c1571b949197d4af 241 Pfam PF07702 UTRA domain 94 233 5.7E-44 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_13950 b872243a77f77b06c1571b949197d4af 241 SUPERFAMILY SSF46785 2 86 7.34E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13950 b872243a77f77b06c1571b949197d4af 241 Gene3D G3DSA:1.10.10.10 8 76 2.6E-31 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13950 b872243a77f77b06c1571b949197d4af 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.4E-22 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_13950 b872243a77f77b06c1571b949197d4af 241 SMART SM00866 94 233 4.7E-47 T 15-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 C2I28_15455 20617d5ad6ffa807696cd2975a0e9425 316 Gene3D G3DSA:3.40.50.1980 35 144 9.4E-28 T 15-10-2018 C2I28_15455 20617d5ad6ffa807696cd2975a0e9425 316 Pfam PF01497 Periplasmic binding protein 60 288 1.0E-36 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_15455 20617d5ad6ffa807696cd2975a0e9425 316 Gene3D G3DSA:3.40.50.1980 146 316 3.0E-61 T 15-10-2018 C2I28_15455 20617d5ad6ffa807696cd2975a0e9425 316 SUPERFAMILY SSF53807 42 306 2.35E-64 T 15-10-2018 C2I28_16620 607e68c8bce9c91df5c4e792b7d5856f 111 Pfam PF03734 L,D-transpeptidase catalytic domain 3 109 2.5E-23 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_16620 607e68c8bce9c91df5c4e792b7d5856f 111 SUPERFAMILY SSF141523 4 110 3.14E-34 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_16620 607e68c8bce9c91df5c4e792b7d5856f 111 Gene3D G3DSA:2.40.440.10 1 111 3.0E-43 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_13695 9c8edd47d0b54ce6c626e2cd3298f726 274 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 274 53.281 T 15-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_13695 9c8edd47d0b54ce6c626e2cd3298f726 274 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 273 1.8E-126 T 15-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_13695 9c8edd47d0b54ce6c626e2cd3298f726 274 Pfam PF00793 DAHP synthetase I family 9 269 1.4E-73 T 15-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 C2I28_13695 9c8edd47d0b54ce6c626e2cd3298f726 274 SUPERFAMILY SSF51569 9 273 1.37E-107 T 15-10-2018 C2I28_13695 9c8edd47d0b54ce6c626e2cd3298f726 274 Gene3D G3DSA:3.20.20.70 1 274 8.6E-108 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_16305 130cf714476dc8abd233b748036ace42 195 Pfam PF16107 Domain of unknown function (DUF4825) 39 130 2.5E-12 T 15-10-2018 IPR032250 Domain of unknown function DUF4825 C2I28_06775 7b0e74d994719a8c7715649c630cdb38 265 Gene3D G3DSA:3.40.190.10 41 262 1.3E-81 T 15-10-2018 C2I28_06775 7b0e74d994719a8c7715649c630cdb38 265 Pfam PF13531 Bacterial extracellular solute-binding protein 39 262 8.1E-53 T 15-10-2018 C2I28_06775 7b0e74d994719a8c7715649c630cdb38 265 Gene3D G3DSA:3.40.190.10 118 225 1.3E-81 T 15-10-2018 C2I28_06775 7b0e74d994719a8c7715649c630cdb38 265 SUPERFAMILY SSF53850 38 263 3.04E-68 T 15-10-2018 C2I28_06775 7b0e74d994719a8c7715649c630cdb38 265 PIRSF PIRSF004846 1 265 1.7E-90 T 15-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 C2I28_06775 7b0e74d994719a8c7715649c630cdb38 265 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 44 261 2.8E-69 T 15-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 C2I28_17385 8abf26d36b2ec5b556f1486349b59d9b 190 Gene3D G3DSA:1.10.10.10 1 166 2.3E-38 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17385 8abf26d36b2ec5b556f1486349b59d9b 190 Pfam PF01047 MarR family 44 101 4.0E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_17385 8abf26d36b2ec5b556f1486349b59d9b 190 SMART SM00347 37 137 2.1E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_17385 8abf26d36b2ec5b556f1486349b59d9b 190 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 15-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I28_17385 8abf26d36b2ec5b556f1486349b59d9b 190 SUPERFAMILY SSF46785 20 126 8.06E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00205 077746027e7543f63023d62992a1d751 569 Gene3D G3DSA:3.90.400.10 120 190 3.3E-191 T 15-10-2018 C2I28_00205 077746027e7543f63023d62992a1d751 569 SUPERFAMILY SSF51445 19 484 5.05E-149 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_00205 077746027e7543f63023d62992a1d751 569 Pfam PF00128 Alpha amylase, catalytic domain 43 388 1.8E-113 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_00205 077746027e7543f63023d62992a1d751 569 Gene3D G3DSA:2.60.40.1180 494 565 9.6E-17 T 15-10-2018 IPR013780 Glycosyl hydrolase, all-beta C2I28_00205 077746027e7543f63023d62992a1d751 569 SUPERFAMILY SSF51011 492 563 1.51E-15 T 15-10-2018 C2I28_00205 077746027e7543f63023d62992a1d751 569 SMART SM00642 28 428 2.1E-142 T 15-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 C2I28_00205 077746027e7543f63023d62992a1d751 569 Gene3D G3DSA:3.20.20.80 20 481 3.3E-191 T 15-10-2018 C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 SUPERFAMILY SSF48498 79 195 1.48E-10 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 SUPERFAMILY SSF46689 6 75 4.16E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 Gene3D G3DSA:1.10.10.60 5 57 5.6E-19 T 15-10-2018 C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 3.1E-16 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 Gene3D G3DSA:1.10.357.10 58 193 2.5E-29 T 15-10-2018 C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.2E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_13120 a1cd7d9bc018e91662edf6b56afbd438 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.2E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_26840 7f5b4bc6181e9f58f4c580237cf52e0a 207 Pfam PF01810 LysE type translocator 12 203 1.5E-37 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_26840 7f5b4bc6181e9f58f4c580237cf52e0a 207 PIRSF PIRSF006324 1 205 3.9E-63 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_04610 89acb6bd2a8bc22d960a0dad0403e8bd 353 Pfam PF01594 AI-2E family transporter 20 346 1.1E-78 T 15-10-2018 IPR002549 Transmembrane protein TqsA-like C2I28_19315 5ad3d111be270fc60fcf0648cad37879 312 Pfam PF04294 VanW like protein 147 276 2.3E-50 T 15-10-2018 IPR007391 Vancomycin resistance VanW C2I28_25040 64d80716c5348f6e7a8a86e0c6574e59 269 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 6 259 2.5E-80 T 15-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 C2I28_25040 64d80716c5348f6e7a8a86e0c6574e59 269 Pfam PF02540 NAD synthase 15 81 2.5E-9 T 15-10-2018 IPR022310 NAD/GMP synthase C2I28_25040 64d80716c5348f6e7a8a86e0c6574e59 269 SUPERFAMILY SSF52402 15 223 1.1E-37 T 15-10-2018 C2I28_25040 64d80716c5348f6e7a8a86e0c6574e59 269 PIRSF PIRSF006661 1 269 1.4E-103 T 15-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 C2I28_25040 64d80716c5348f6e7a8a86e0c6574e59 269 Gene3D G3DSA:3.40.50.620 5 168 7.7E-29 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 15-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 SMART SM01274 15 148 4.2E-87 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 PIRSF PIRSF000106 35 406 1.9E-86 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 Gene3D G3DSA:3.40.50.720 158 409 6.8E-90 T 15-10-2018 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 SUPERFAMILY SSF53223 6 158 3.38E-58 T 15-10-2018 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 SUPERFAMILY SSF51735 160 401 8.72E-84 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 Gene3D G3DSA:3.40.50.10380 1 157 2.3E-76 T 15-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 PRINTS PR00072 Malic enzyme signature 276 292 1.3E-7 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 PRINTS PR00072 Malic enzyme signature 77 99 1.3E-7 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 PRINTS PR00072 Malic enzyme signature 156 172 1.3E-7 T 15-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 4.9E-31 T 15-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 SMART SM00919 160 384 8.4E-131 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_05445 11ae224808cd53768f3095e97986e3fc 409 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 1.9E-25 T 15-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 Pfam PF07698 7TM receptor with intracellular HD hydrolase 247 443 9.6E-42 T 15-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 SMART SM00471 464 620 5.3E-12 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 Gene3D G3DSA:1.10.3210.10 441 648 1.2E-26 T 15-10-2018 C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 Pfam PF01966 HD domain 468 610 6.6E-20 T 15-10-2018 IPR006674 HD domain C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 Pfam PF07697 7TM-HD extracellular 20 240 6.6E-35 T 15-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 TIGRFAM TIGR00277 HDIG: HDIG domain 465 563 5.4E-29 T 15-10-2018 IPR006675 HDIG domain C2I28_04315 eff87b8bed03e9857d338e96657563fd 681 SUPERFAMILY SSF109604 467 616 5.42E-17 T 15-10-2018 C2I28_25025 c000f9331308ff763afbbd0191ff06e8 159 Gene3D G3DSA:3.10.20.300 96 158 1.7E-5 T 15-10-2018 C2I28_25025 c000f9331308ff763afbbd0191ff06e8 159 Pfam PF01969 Protein of unknown function DUF111 13 147 2.9E-47 T 15-10-2018 IPR002822 Nickel insertion protein C2I28_25025 c000f9331308ff763afbbd0191ff06e8 159 Gene3D G3DSA:3.30.70.1380 7 95 9.7E-20 T 15-10-2018 C2I28_18720 731b98debe7c5a1648cca1fcb805cbc4 346 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 106 303 2.8E-51 T 15-10-2018 IPR005079 Peptidase C45 C2I28_18720 731b98debe7c5a1648cca1fcb805cbc4 346 SUPERFAMILY SSF56235 106 234 5.48E-15 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_18720 731b98debe7c5a1648cca1fcb805cbc4 346 Gene3D G3DSA:3.60.60.10 98 314 6.2E-33 T 15-10-2018 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 412 470 9.4E-8 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Gene3D G3DSA:3.40.930.10 533 683 4.9E-14 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Gene3D G3DSA:1.10.1790.10 199 295 7.1E-9 T 15-10-2018 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 SUPERFAMILY SSF63520 193 292 3.14E-10 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 548 682 8.0E-14 T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 SUPERFAMILY SSF52794 410 488 2.25E-12 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 SUPERFAMILY SSF55804 539 682 4.19E-16 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Pfam PF08279 HTH domain 8 50 2.3E-8 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Pfam PF08279 HTH domain 95 148 5.9E-6 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Gene3D G3DSA:3.40.50.2300 410 497 3.8E-13 T 15-10-2018 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Gene3D G3DSA:1.10.1790.10 306 401 3.4E-17 T 15-10-2018 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Gene3D G3DSA:1.10.10.10 5 89 1.3E-5 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Pfam PF00874 PRD domain 313 399 3.6E-18 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 Pfam PF00874 PRD domain 207 289 1.2E-8 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_09020 999cb59ba217996bc3523d4f729dd72b 696 SUPERFAMILY SSF63520 309 400 1.15E-19 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_15995 58b0eca133356708043443c501f7640a 274 PRINTS PR00069 Aldo-keto reductase signature 156 185 5.0E-52 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 PRINTS PR00069 Aldo-keto reductase signature 34 58 5.0E-52 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 PRINTS PR00069 Aldo-keto reductase signature 90 108 5.0E-52 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 PRINTS PR00069 Aldo-keto reductase signature 122 139 5.0E-52 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 PRINTS PR00069 Aldo-keto reductase signature 194 218 5.0E-52 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 Gene3D G3DSA:3.20.20.100 1 273 2.3E-122 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_15995 58b0eca133356708043443c501f7640a 274 SUPERFAMILY SSF51430 3 263 5.89E-103 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_15995 58b0eca133356708043443c501f7640a 274 PIRSF PIRSF000097 1 271 5.8E-101 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 227 242 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_15995 58b0eca133356708043443c501f7640a 274 Pfam PF00248 Aldo/keto reductase family 15 258 2.3E-63 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 7.5E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.5E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.5E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 SUPERFAMILY SSF51735 6 251 1.9E-85 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 2.0E-65 T 15-10-2018 C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.1E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.1E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_24785 95fa1f0be4c3b1e86712b2d9dc9e22cf 261 Gene3D G3DSA:3.40.50.720 1 261 3.2E-91 T 15-10-2018 C2I28_10525 7cacece15991ba1c3333bdd61ed533fe 165 Gene3D G3DSA:3.40.630.30 1 156 5.4E-15 T 15-10-2018 C2I28_10525 7cacece15991ba1c3333bdd61ed533fe 165 Pfam PF13527 Acetyltransferase (GNAT) domain 3 128 2.0E-9 T 15-10-2018 C2I28_10525 7cacece15991ba1c3333bdd61ed533fe 165 SUPERFAMILY SSF55729 1 134 6.56E-15 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_20060 e95b5b64b4f39a40c994bf13ff24ef6a 888 Gene3D G3DSA:1.20.1640.10 131 339 1.0E-11 T 15-10-2018 C2I28_20060 e95b5b64b4f39a40c994bf13ff24ef6a 888 SUPERFAMILY SSF82866 669 876 2.35E-28 T 15-10-2018 C2I28_20060 e95b5b64b4f39a40c994bf13ff24ef6a 888 SUPERFAMILY SSF82866 118 333 3.27E-34 T 15-10-2018 C2I28_20060 e95b5b64b4f39a40c994bf13ff24ef6a 888 SUPERFAMILY SSF58104 463 606 4.45E-5 T 15-10-2018 C2I28_20060 e95b5b64b4f39a40c994bf13ff24ef6a 888 Pfam PF03176 MMPL family 41 358 1.6E-72 T 15-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I28_20060 e95b5b64b4f39a40c994bf13ff24ef6a 888 Pfam PF03176 MMPL family 542 877 7.2E-46 T 15-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I28_19450 1a768cd22a5754072815d8367f920643 139 Gene3D G3DSA:3.30.300.20 44 136 1.7E-33 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_19450 1a768cd22a5754072815d8367f920643 139 SUPERFAMILY SSF82784 5 135 4.97E-38 T 15-10-2018 IPR036102 OsmC/Ohr superfamily C2I28_19450 1a768cd22a5754072815d8367f920643 139 Gene3D G3DSA:2.20.25.10 3 43 1.7E-14 T 15-10-2018 C2I28_19450 1a768cd22a5754072815d8367f920643 139 Pfam PF02566 OsmC-like protein 40 134 9.5E-18 T 15-10-2018 IPR003718 OsmC/Ohr family C2I28_19450 1a768cd22a5754072815d8367f920643 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 135 5.5E-52 T 15-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 C2I28_18630 9f94a11863d308d7536cf3d442481d4b 142 Gene3D G3DSA:2.30.110.10 4 142 3.0E-36 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_18630 9f94a11863d308d7536cf3d442481d4b 142 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 128 3.9E-16 T 15-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain C2I28_18630 9f94a11863d308d7536cf3d442481d4b 142 SUPERFAMILY SSF50475 6 134 1.27E-28 T 15-10-2018 C2I28_17820 ef1ef1e5f1678cdf8119fcd267bfd107 141 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 43 135 1.9E-9 T 15-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 C2I28_17820 ef1ef1e5f1678cdf8119fcd267bfd107 141 Gene3D G3DSA:3.40.50.300 26 137 2.2E-9 T 15-10-2018 C2I28_17820 ef1ef1e5f1678cdf8119fcd267bfd107 141 SUPERFAMILY SSF52540 1 137 5.04E-13 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21550 ac0edfa626973497ff884ed2923a2700 253 SUPERFAMILY SSF56219 1 249 6.54E-76 T 15-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I28_21550 ac0edfa626973497ff884ed2923a2700 253 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 248 5.8E-96 T 15-10-2018 C2I28_21550 ac0edfa626973497ff884ed2923a2700 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 241 6.2E-24 T 15-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase C2I28_21550 ac0edfa626973497ff884ed2923a2700 253 Gene3D G3DSA:3.60.10.10 1 249 5.9E-93 T 15-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily C2I28_21550 ac0edfa626973497ff884ed2923a2700 253 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 15-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 C2I28_21550 ac0edfa626973497ff884ed2923a2700 253 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 249 3.2E-97 T 15-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 Gene3D G3DSA:3.40.50.2000 179 341 9.2E-39 T 15-10-2018 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 Gene3D G3DSA:3.40.50.2000 1 178 3.8E-60 T 15-10-2018 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 342 5.5E-30 T 15-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 SUPERFAMILY SSF53756 6 354 9.16E-94 T 15-10-2018 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 143 1.1E-41 T 15-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 355 29.706 T 15-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_23285 a681fbf43516fedfb42e50bfbafa5426 355 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 349 1.2E-81 T 15-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 Gene3D G3DSA:2.40.30.20 101 202 3.1E-33 T 15-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 SUPERFAMILY SSF63380 1 89 4.76E-27 T 15-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 Pfam PF00677 Lumazine binding domain 99 183 6.9E-23 T 15-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 Pfam PF00677 Lumazine binding domain 3 86 2.1E-24 T 15-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 SUPERFAMILY SSF63380 92 195 2.55E-31 T 15-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 PIRSF PIRSF000498 1 210 3.6E-77 T 15-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 Gene3D G3DSA:2.40.30.20 1 88 9.9E-32 T 15-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 C2I28_14525 be9ec74efa9d9c90f7b2e3dd57ee6608 219 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 2.6E-75 T 15-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 C2I28_21000 b4f28e3ad703f7d7e7fa7f3772dec8ff 156 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 3 133 5.0E-5 T 15-10-2018 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7|MetaCyc: PWY-7824 C2I28_21000 b4f28e3ad703f7d7e7fa7f3772dec8ff 156 Pfam PF13826 Domain of unknown function (DUF4188) 15 131 7.4E-45 T 15-10-2018 IPR025444 Monooxygenase af470-like C2I28_19380 872992d116d8d12de2b3319ac35fcfc2 870 Gene3D G3DSA:3.40.50.300 524 668 1.5E-100 T 15-10-2018 C2I28_19380 872992d116d8d12de2b3319ac35fcfc2 870 Gene3D G3DSA:3.40.50.300 382 523 1.5E-100 T 15-10-2018 C2I28_19380 872992d116d8d12de2b3319ac35fcfc2 870 SMART SM00490 555 644 1.3E-19 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_19380 872992d116d8d12de2b3319ac35fcfc2 870 Gene3D G3DSA:1.20.272.40 669 737 1.5E-100 T 15-10-2018 C2I28_19380 872992d116d8d12de2b3319ac35fcfc2 870 Pfam PF00271 Helicase conserved C-terminal domain 538 644 1.6E-14 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_19380 872992d116d8d12de2b3319ac35fcfc2 870 SUPERFAMILY SSF52540 385 652 2.54E-31 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15505 a631d85ddfe69463247414a798642c6b 380 Pfam PF07730 Histidine kinase 182 245 2.6E-22 T 15-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I28_15505 a631d85ddfe69463247414a798642c6b 380 SUPERFAMILY SSF55874 253 369 4.58E-14 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_15505 a631d85ddfe69463247414a798642c6b 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 285 369 3.1E-7 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_15505 a631d85ddfe69463247414a798642c6b 380 Gene3D G3DSA:3.30.565.10 246 371 2.6E-31 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 SMART SM00065 24 175 0.0022 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 Pfam PF07730 Histidine kinase 182 247 5.1E-15 T 15-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 SUPERFAMILY SSF55781 25 170 1.11E-18 T 15-10-2018 C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 Gene3D G3DSA:3.30.565.10 241 372 1.2E-22 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 Pfam PF13185 GAF domain 24 165 2.5E-12 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 SUPERFAMILY SSF55874 247 371 1.64E-14 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_20620 76e21ea704032b16ad8b6efb5798d010 372 Gene3D G3DSA:3.30.450.40 3 178 3.6E-20 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_14200 41cbe5092d062eadd74d19d4f0239895 170 TIGRFAM TIGR02131 phaP_Bmeg: polyhydroxyalkanoic acid inclusion protein PhaP 1 165 3.8E-87 T 15-10-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP C2I28_14200 41cbe5092d062eadd74d19d4f0239895 170 Pfam PF09602 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 1 165 2.3E-68 T 15-10-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP C2I28_11755 5ce9bbec2bdbbe3781271e80e3289ac6 253 TIGRFAM TIGR00808 malonate_madM: malonate transporter, MadM subunit 1 252 3.9E-116 T 15-10-2018 IPR004691 Malonate/sodium symporter MadM subunit GO:0044668 C2I28_11755 5ce9bbec2bdbbe3781271e80e3289ac6 253 Pfam PF03818 Malonate/sodium symporter MadM subunit 4 61 6.8E-27 T 15-10-2018 IPR018402 Malonate/sodium symporter MadM subunit, N-terminal C2I28_20030 ed81ed7f98354151f2a34ad37956cee1 580 SUPERFAMILY SSF53649 3 557 9.03E-77 T 15-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 C2I28_20030 ed81ed7f98354151f2a34ad37956cee1 580 Pfam PF00884 Sulfatase 5 385 1.1E-56 T 15-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 C2I28_20030 ed81ed7f98354151f2a34ad37956cee1 580 Gene3D G3DSA:3.40.720.10 1 577 1.1E-79 T 15-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 C2I28_14140 cffcc14ff510dfb193d5aad487ec5453 166 Pfam PF13411 MerR HTH family regulatory protein 4 69 2.9E-6 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_14140 cffcc14ff510dfb193d5aad487ec5453 166 Gene3D G3DSA:1.10.1660.10 1 65 7.8E-17 T 15-10-2018 C2I28_14140 cffcc14ff510dfb193d5aad487ec5453 166 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 166 19.296 T 15-10-2018 IPR023522 Chromosome-anchoring protein RacA C2I28_07790 d5ea338f13746d201d7440537f9bb367 477 PIRSF PIRSF002457 1 477 6.9E-162 T 15-10-2018 IPR030676 Citrate carrier CitT-related C2I28_07790 d5ea338f13746d201d7440537f9bb367 477 Pfam PF00939 Sodium:sulfate symporter transmembrane region 13 477 2.8E-168 T 15-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 C2I28_07790 d5ea338f13746d201d7440537f9bb367 477 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 33 471 7.6E-136 T 15-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 C2I28_03075 36e273ab1ab00c205117fe7c3c6e7d79 189 Gene3D G3DSA:3.40.50.150 1 183 5.5E-56 T 15-10-2018 C2I28_03075 36e273ab1ab00c205117fe7c3c6e7d79 189 Pfam PF03602 Conserved hypothetical protein 95 1 180 2.7E-54 T 15-10-2018 C2I28_03075 36e273ab1ab00c205117fe7c3c6e7d79 189 PIRSF PIRSF004553 1 184 2.3E-47 T 15-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 C2I28_03075 36e273ab1ab00c205117fe7c3c6e7d79 189 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 179 3.3E-52 T 15-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 C2I28_03075 36e273ab1ab00c205117fe7c3c6e7d79 189 SUPERFAMILY SSF53335 1 180 1.14E-47 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_08010 febbbfcfdbfb2692f906664417c08b7d 44 Pfam PF00468 Ribosomal protein L34 1 44 1.2E-23 T 15-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08010 febbbfcfdbfb2692f906664417c08b7d 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 7.7E-21 T 15-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08010 febbbfcfdbfb2692f906664417c08b7d 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 7.0E-7 T 15-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08010 febbbfcfdbfb2692f906664417c08b7d 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.018 T 15-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08010 febbbfcfdbfb2692f906664417c08b7d 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 15-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_22350 51018947af72bccd0e9a0ff8194a1267 265 SUPERFAMILY SSF52540 6 242 9.65E-54 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_22350 51018947af72bccd0e9a0ff8194a1267 265 SMART SM00382 30 228 2.5E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_22350 51018947af72bccd0e9a0ff8194a1267 265 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_22350 51018947af72bccd0e9a0ff8194a1267 265 Pfam PF00005 ABC transporter 22 170 4.9E-26 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_22350 51018947af72bccd0e9a0ff8194a1267 265 Gene3D G3DSA:3.40.50.300 2 264 3.4E-69 T 15-10-2018 C2I28_08765 fa33922a553cef04b5b8ee694a919a54 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 2.6E-53 T 15-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08765 fa33922a553cef04b5b8ee694a919a54 120 SUPERFAMILY SSF53137 7 118 2.09E-56 T 15-10-2018 C2I28_08765 fa33922a553cef04b5b8ee694a919a54 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.3E-49 T 15-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08765 fa33922a553cef04b5b8ee694a919a54 120 Gene3D G3DSA:3.30.420.100 5 120 6.0E-48 T 15-10-2018 C2I28_08765 fa33922a553cef04b5b8ee694a919a54 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.521 T 15-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_16050 0e6a3444dc677ca1fbc66660e77c9550 358 Gene3D G3DSA:3.40.50.880 56 329 8.7E-53 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16050 0e6a3444dc677ca1fbc66660e77c9550 358 SUPERFAMILY SSF52317 89 279 6.72E-16 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16050 0e6a3444dc677ca1fbc66660e77c9550 358 Pfam PF03575 Peptidase family S51 63 275 4.4E-12 T 15-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 SUPERFAMILY SSF50677 198 384 1.15E-50 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 SUPERFAMILY SSF47323 946 1017 6.67E-6 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 2.4E-29 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 2.4E-29 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 382 397 2.4E-29 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 2.4E-29 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 2.4E-29 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 Gene3D G3DSA:3.40.50.620 14 615 8.4E-251 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 Gene3D G3DSA:1.10.730.10 631 810 4.3E-51 T 15-10-2018 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 Pfam PF08264 Anticodon-binding domain of tRNA 675 818 5.2E-32 T 15-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 Gene3D G3DSA:3.90.740.10 196 388 8.4E-251 T 15-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 15-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 SUPERFAMILY SSF47323 645 878 1.87E-52 T 15-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 6 827 2.5E-295 T 15-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 620 9.7E-198 T 15-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 SUPERFAMILY SSF52374 10 637 1.77E-138 T 15-10-2018 C2I28_21750 43fa247565a7e3e1e59d748b5054a11c 1032 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1018 13.864 T 15-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I28_15700 c4a1ac8612718b0b10996aabb995ec71 386 Gene3D G3DSA:3.50.50.60 6 368 8.4E-117 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_15700 c4a1ac8612718b0b10996aabb995ec71 386 SUPERFAMILY SSF51905 4 381 6.15E-44 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_15700 c4a1ac8612718b0b10996aabb995ec71 386 SUPERFAMILY SSF54373 218 323 3.22E-19 T 15-10-2018 C2I28_15700 c4a1ac8612718b0b10996aabb995ec71 386 Gene3D G3DSA:3.30.9.10 61 323 8.4E-117 T 15-10-2018 C2I28_15700 c4a1ac8612718b0b10996aabb995ec71 386 Pfam PF01266 FAD dependent oxidoreductase 6 362 3.2E-45 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_24155 643bc82138d9fb5c5d721afc1d3684cc 122 SUPERFAMILY SSF54427 4 119 7.33E-19 T 15-10-2018 IPR032710 NTF2-like domain superfamily C2I28_24155 643bc82138d9fb5c5d721afc1d3684cc 122 Gene3D G3DSA:3.10.450.50 2 120 1.9E-23 T 15-10-2018 C2I28_24155 643bc82138d9fb5c5d721afc1d3684cc 122 Pfam PF14534 Domain of unknown function (DUF4440) 8 110 9.7E-13 T 15-10-2018 IPR027843 Domain of unknown function DUF4440 C2I28_04885 96db3f1d5ed3332bc802a03d624586f2 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 158 4.5E-32 T 15-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 C2I28_04885 96db3f1d5ed3332bc802a03d624586f2 172 Pfam PF04093 rod shape-determining protein MreD 2 163 1.4E-27 T 15-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 C2I28_04350 b5aa3620596bfaba55c937a8b3ef233d 147 Gene3D G3DSA:1.10.1510.10 1 90 2.6E-30 T 15-10-2018 C2I28_04350 b5aa3620596bfaba55c937a8b3ef233d 147 Pfam PF09424 Yqey-like protein 5 146 6.6E-54 T 15-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 C2I28_04350 b5aa3620596bfaba55c937a8b3ef233d 147 Gene3D G3DSA:1.10.10.410 91 147 3.6E-25 T 15-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal C2I28_04350 b5aa3620596bfaba55c937a8b3ef233d 147 SUPERFAMILY SSF89095 1 146 6.8E-43 T 15-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 C2I28_24865 0cd979b80f2df2446ac78891bae0cb5f 87 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 57 77 1.0E-9 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_24865 0cd979b80f2df2446ac78891bae0cb5f 87 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 59 78 9.9E-9 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_04300 719067315f8a6751d98456f633e35a5b 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 15-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 C2I28_04300 719067315f8a6751d98456f633e35a5b 132 SUPERFAMILY SSF53927 4 130 2.01E-48 T 15-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 C2I28_04300 719067315f8a6751d98456f633e35a5b 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 103 2.0E-17 T 15-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain C2I28_04300 719067315f8a6751d98456f633e35a5b 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 129 1.3E-46 T 15-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 C2I28_04300 719067315f8a6751d98456f633e35a5b 132 Gene3D G3DSA:3.40.140.10 1 132 1.0E-57 T 15-10-2018 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 SUPERFAMILY SSF50249 2 125 7.54E-52 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 SUPERFAMILY SSF50104 126 273 1.75E-62 T 15-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 15-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 Gene3D G3DSA:4.10.950.10 197 276 1.0E-37 T 15-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 SMART SM01382 124 253 6.6E-96 T 15-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 SMART SM01383 42 118 4.3E-46 T 15-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 PIRSF PIRSF002158 3 276 4.1E-102 T 15-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 Gene3D G3DSA:2.30.30.30 118 196 6.4E-36 T 15-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 Gene3D G3DSA:2.40.50.140 1 113 1.7E-49 T 15-10-2018 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 5.4E-34 T 15-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 6.8E-142 T 15-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.467 T 15-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 C2I28_08700 54188f15a8161f02c2979b7f18b9a289 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 2.4E-58 T 15-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 C2I28_11905 ab8f904eb13a1939b258c75558e43552 144 Pfam PF13673 Acetyltransferase (GNAT) domain 21 140 1.7E-24 T 15-10-2018 IPR000182 GNAT domain C2I28_11905 ab8f904eb13a1939b258c75558e43552 144 Gene3D G3DSA:3.40.630.30 1 139 2.9E-44 T 15-10-2018 C2I28_11905 ab8f904eb13a1939b258c75558e43552 144 SUPERFAMILY SSF55729 7 141 6.58E-36 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_16365 54f82714e6fb5405dda4842e1684ae25 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 363 7.2E-59 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_16365 54f82714e6fb5405dda4842e1684ae25 367 Pfam PF03845 Spore germination protein 5 324 9.3E-63 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_07865 067616b12286739cb573fe9f481aa242 455 Pfam PF07435 YycH protein 6 455 4.8E-89 T 15-10-2018 IPR009996 Regulatory protein YycH C2I28_07865 067616b12286739cb573fe9f481aa242 455 Gene3D G3DSA:3.10.450.310 203 407 3.7E-63 T 15-10-2018 C2I28_07865 067616b12286739cb573fe9f481aa242 455 Gene3D G3DSA:3.30.310.160 225 369 3.7E-63 T 15-10-2018 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 Pfam PF00224 Pyruvate kinase, barrel domain 6 331 2.7E-113 T 15-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 Gene3D G3DSA:2.40.33.10 66 160 1.2E-126 T 15-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 306 322 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 179 193 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 287 305 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 210 236 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 262 286 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 54 70 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 PRINTS PR01050 Pyruvate kinase family signature 237 261 3.2E-56 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 SUPERFAMILY SSF51621 6 333 1.01E-80 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 SUPERFAMILY SSF50800 65 160 1.22E-25 T 15-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 Gene3D G3DSA:3.20.20.60 6 335 1.2E-126 T 15-10-2018 C2I28_15725 cc3196e23a15db60bf066ada6a627b1e 350 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 338 1.2E-129 T 15-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 Pfam PF04542 Sigma-70 region 2 24 91 1.8E-20 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 178 4.0E-34 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 Gene3D G3DSA:1.10.10.10 97 180 3.4E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 SUPERFAMILY SSF88659 99 179 5.23E-16 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 Pfam PF04545 Sigma-70, region 4 128 175 3.3E-11 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 Gene3D G3DSA:1.10.1740.10 7 88 3.5E-27 T 15-10-2018 C2I28_17885 cb137e2005630e257506c4212eb6b5dc 188 SUPERFAMILY SSF88946 2 107 6.44E-29 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_05290 c69bcb91942a9e83d4f16824eef5f34d 162 SUPERFAMILY SSF101386 2 162 5.56E-41 T 15-10-2018 C2I28_05290 c69bcb91942a9e83d4f16824eef5f34d 162 PIRSF PIRSF030140 1 162 9.2E-57 T 15-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 C2I28_05290 c69bcb91942a9e83d4f16824eef5f34d 162 Gene3D G3DSA:1.10.4010.10 1 162 1.2E-15 T 15-10-2018 C2I28_05290 c69bcb91942a9e83d4f16824eef5f34d 162 Pfam PF08761 dUTPase 2 162 4.1E-50 T 15-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 C2I28_15305 2218ea5d49788303fb1d59414eeb71ae 187 Gene3D G3DSA:1.20.120.1630 1 182 9.3E-21 T 15-10-2018 C2I28_15305 2218ea5d49788303fb1d59414eeb71ae 187 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 76 164 2.1E-25 T 15-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 C2I28_05090 784c477f1af1268db7c71b4ccfa5e6cd 204 Pfam PF08000 Bacterial PH domain 11 132 6.0E-37 T 15-10-2018 IPR012544 Bacterial Pleckstrin homology domain C2I28_05090 784c477f1af1268db7c71b4ccfa5e6cd 204 Gene3D G3DSA:1.10.287.210 116 204 1.7E-30 T 15-10-2018 C2I28_05090 784c477f1af1268db7c71b4ccfa5e6cd 204 Gene3D G3DSA:2.30.29.50 12 115 3.5E-46 T 15-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily C2I28_05090 784c477f1af1268db7c71b4ccfa5e6cd 204 SUPERFAMILY SSF50729 14 203 3.57E-67 T 15-10-2018 C2I28_05090 784c477f1af1268db7c71b4ccfa5e6cd 204 Pfam PF11724 YvbH-like oligomerisation region 144 204 4.1E-23 T 15-10-2018 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Pfam PF00258 Flavodoxin 485 617 7.3E-25 T 15-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Pfam PF00667 FAD binding domain 661 868 1.3E-39 T 15-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PIRSF PIRSF000209 1 1049 0.0 T 15-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 SUPERFAMILY SSF52343 888 1047 4.32E-46 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Gene3D G3DSA:3.40.50.360 480 631 2.9E-44 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Gene3D G3DSA:2.40.30.10 670 878 5.7E-78 T 15-10-2018 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 SUPERFAMILY SSF48264 4 451 5.11E-105 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 SUPERFAMILY SSF63380 655 884 4.09E-61 T 15-10-2018 IPR017938 Riboflavin synthase-like beta-barrel C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00369 Flavodoxin signature 562 572 4.3E-8 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00369 Flavodoxin signature 587 606 4.3E-8 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00369 Flavodoxin signature 484 497 4.3E-8 T 15-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Pfam PF00067 Cytochrome P450 11 448 2.1E-78 T 15-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Gene3D G3DSA:1.10.630.10 2 471 5.7E-196 T 15-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Pfam PF00175 Oxidoreductase NAD-binding domain 901 1011 2.4E-16 T 15-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 863 872 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 942 953 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 900 919 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 996 1004 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 929 938 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 828 835 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 695 705 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 973 989 2.8E-32 T 15-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 394 403 - T 15-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Gene3D G3DSA:1.20.990.10 705 826 5.7E-78 T 15-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 SUPERFAMILY SSF52218 479 633 1.08E-40 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24145 ca3d882c39490af8b858845c1cfcd88e 1049 Gene3D G3DSA:3.40.50.80 889 1049 1.9E-59 T 15-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain C2I28_19090 3c554b84e89412aef54f5856efd752e4 294 SUPERFAMILY SSF103481 184 284 8.37E-14 T 15-10-2018 C2I28_19090 3c554b84e89412aef54f5856efd752e4 294 SUPERFAMILY SSF103481 40 141 6.15E-11 T 15-10-2018 C2I28_19090 3c554b84e89412aef54f5856efd752e4 294 Pfam PF00892 EamA-like transporter family 8 138 1.3E-18 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_19090 3c554b84e89412aef54f5856efd752e4 294 Pfam PF00892 EamA-like transporter family 148 281 6.5E-21 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_13680 9dc34cb67a75968e348d5f3de9d8c6c9 388 Gene3D G3DSA:3.40.50.2000 18 372 3.1E-47 T 15-10-2018 C2I28_13680 9dc34cb67a75968e348d5f3de9d8c6c9 388 Gene3D G3DSA:3.40.50.2000 177 359 3.1E-47 T 15-10-2018 C2I28_13680 9dc34cb67a75968e348d5f3de9d8c6c9 388 Pfam PF00534 Glycosyl transferases group 1 195 357 1.6E-31 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_13680 9dc34cb67a75968e348d5f3de9d8c6c9 388 Pfam PF13439 Glycosyltransferase Family 4 18 176 6.8E-9 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_13680 9dc34cb67a75968e348d5f3de9d8c6c9 388 SUPERFAMILY SSF53756 16 378 8.24E-68 T 15-10-2018 C2I28_02695 b3c9eb60448520c2db8ec0603eb08ca9 295 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 292 6.4E-148 T 15-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 C2I28_02695 b3c9eb60448520c2db8ec0603eb08ca9 295 Pfam PF03313 Serine dehydratase alpha chain 15 274 1.3E-76 T 15-10-2018 IPR005130 Serine dehydratase-like, alpha subunit C2I28_20745 f43e6ff2fdd4c8a9bbec52ec53c32589 262 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 133 225 1.7E-13 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_20745 f43e6ff2fdd4c8a9bbec52ec53c32589 262 Gene3D G3DSA:1.10.150.240 15 131 2.4E-47 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_20745 f43e6ff2fdd4c8a9bbec52ec53c32589 262 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 231 7.8E-23 T 15-10-2018 C2I28_20745 f43e6ff2fdd4c8a9bbec52ec53c32589 262 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 132 231 6.6E-8 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_20745 f43e6ff2fdd4c8a9bbec52ec53c32589 262 Gene3D G3DSA:3.40.50.1000 4 253 2.4E-47 T 15-10-2018 IPR023214 HAD superfamily C2I28_20745 f43e6ff2fdd4c8a9bbec52ec53c32589 262 SUPERFAMILY SSF56784 1 259 7.74E-42 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_02505 e5f39cbb95d6b507b4f39da9adcacda3 210 Pfam PF03448 MgtE intracellular N domain 152 204 8.8E-6 T 15-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain C2I28_02505 e5f39cbb95d6b507b4f39da9adcacda3 210 SUPERFAMILY SSF158791 148 204 2.35E-7 T 15-10-2018 C2I28_10015 d3dc2861ac4cbba26a55cb8e03397a1b 269 SUPERFAMILY SSF88713 54 256 6.43E-66 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_10015 d3dc2861ac4cbba26a55cb8e03397a1b 269 Pfam PF01522 Polysaccharide deacetylase 64 186 1.4E-34 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_10015 d3dc2861ac4cbba26a55cb8e03397a1b 269 Gene3D G3DSA:3.20.20.370 18 260 5.3E-87 T 15-10-2018 C2I28_10015 d3dc2861ac4cbba26a55cb8e03397a1b 269 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 33 255 2.6E-111 T 15-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA C2I28_21765 0d7bb5bf49d6b0d36b820b8fd8115c5b 392 SUPERFAMILY SSF57884 350 391 5.89E-5 T 15-10-2018 IPR035451 Ada-like domain superfamily C2I28_12220 b6cc05c00a97b5a94e1050c45ceba36e 531 PIRSF PIRSF006060 1 531 7.8E-73 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_12220 b6cc05c00a97b5a94e1050c45ceba36e 531 Gene3D G3DSA:1.20.1740.10 1 459 4.4E-76 T 15-10-2018 C2I28_12220 b6cc05c00a97b5a94e1050c45ceba36e 531 Pfam PF13520 Amino acid permease 9 424 2.1E-46 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_08350 2ce095531200a35693ce495e6d97d033 96 Gene3D G3DSA:3.30.1120.40 1 96 4.1E-39 T 15-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 C2I28_08350 2ce095531200a35693ce495e6d97d033 96 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.49 T 15-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 C2I28_08350 2ce095531200a35693ce495e6d97d033 96 SUPERFAMILY SSF160537 1 89 6.02E-34 T 15-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 C2I28_08350 2ce095531200a35693ce495e6d97d033 96 Pfam PF04026 SpoVG 1 81 2.7E-36 T 15-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 C2I28_15980 6ad9e48bccd4dda349a3a8c0cb834783 102 SUPERFAMILY SSF143579 2 97 1.19E-31 T 15-10-2018 IPR028990 GK1464-like C2I28_15980 6ad9e48bccd4dda349a3a8c0cb834783 102 Gene3D G3DSA:3.30.70.1480 1 100 1.8E-37 T 15-10-2018 IPR028990 GK1464-like C2I28_01050 74a476590fcda86d76dea731ad92d743 408 Gene3D G3DSA:3.30.300.210 244 397 6.8E-36 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_01050 74a476590fcda86d76dea731ad92d743 408 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 228 393 2.6E-36 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_01050 74a476590fcda86d76dea731ad92d743 408 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 395 9.3E-93 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 Pfam PF00107 Zinc-binding dehydrogenase 151 258 8.9E-28 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 Gene3D G3DSA:3.90.180.10 9 317 3.8E-97 T 15-10-2018 C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 SUPERFAMILY SSF50129 1 144 3.96E-37 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 SUPERFAMILY SSF51735 111 273 1.39E-41 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 15-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 SMART SM00829 10 318 2.5E-28 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 6.4E-11 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_21685 5f55f5e46342382ec986ed85dc3d4184 320 Gene3D G3DSA:3.40.50.720 123 264 3.8E-97 T 15-10-2018 C2I28_22535 0f09b9967cf880e010332b780e8a42c6 106 Pfam PF17280 Family of unknown function (DUF5345) 13 89 2.3E-23 T 15-10-2018 IPR035238 Protein of unknown function DUF5345 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 Gene3D G3DSA:3.40.50.720 22 198 2.6E-57 T 15-10-2018 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 SUPERFAMILY SSF51735 17 213 3.94E-57 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 Gene3D G3DSA:3.30.360.10 199 504 3.0E-109 T 15-10-2018 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 351 377 3.0E-42 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 260 276 3.0E-42 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 179 3.0E-42 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 190 218 3.0E-42 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 242 259 3.0E-42 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 SUPERFAMILY SSF55347 205 504 1.34E-98 T 15-10-2018 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 28 210 6.1E-60 T 15-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 24 504 74.605 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 214 503 8.5E-99 T 15-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 PIRSF PIRSF000110 9 504 9.5E-177 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_15680 da7229cdff2eeabf08af77a600ac4bff 504 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 25 504 1.2E-164 T 15-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 C2I28_10530 fcca562b136169b06709493a1983243f 590 SUPERFAMILY SSF53474 125 358 9.4E-38 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10530 fcca562b136169b06709493a1983243f 590 SUPERFAMILY SSF53474 28 128 1.22E-23 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10530 fcca562b136169b06709493a1983243f 590 Gene3D G3DSA:3.40.50.1820 18 323 3.6E-64 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10530 fcca562b136169b06709493a1983243f 590 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 39 240 1.2E-52 T 15-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 C2I28_10530 fcca562b136169b06709493a1983243f 590 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 342 407 6.1E-22 T 15-10-2018 C2I28_10530 fcca562b136169b06709493a1983243f 590 Pfam PF10503 Esterase PHB depolymerase 37 241 1.1E-58 T 15-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 203 431 1.1E-89 T 15-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 SUPERFAMILY SSF52777 194 431 5.34E-90 T 15-10-2018 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 Pfam PF00364 Biotin-requiring enzyme 4 75 7.9E-23 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 Gene3D G3DSA:3.30.559.10 183 429 1.4E-92 T 15-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 15-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 Gene3D G3DSA:2.40.50.100 2 81 3.9E-25 T 15-10-2018 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 SUPERFAMILY SSF51230 3 93 6.15E-26 T 15-10-2018 IPR011053 Single hybrid motif C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 SUPERFAMILY SSF47005 121 166 4.45E-13 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 Gene3D G3DSA:4.10.320.10 115 169 4.6E-22 T 15-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 C2I28_14780 13ddc66e0111665a69f7500262ab3012 433 Pfam PF02817 e3 binding domain 127 161 6.4E-16 T 15-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 15-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 Pfam PF01180 Dihydroorotate dehydrogenase 3 286 5.3E-94 T 15-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 SUPERFAMILY SSF51395 2 302 7.33E-88 T 15-10-2018 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 41.329 T 15-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 5.7E-125 T 15-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 PIRSF PIRSF000164 1 303 2.2E-86 T 15-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 15-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 C2I28_02825 998b84a4384659e0d454833c72c08c4c 313 Gene3D G3DSA:3.20.20.70 2 305 1.8E-97 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_00240 90f0e53c429c1ad151ad5f44a6f38f97 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 374 1.0E-110 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_00240 90f0e53c429c1ad151ad5f44a6f38f97 400 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_00240 90f0e53c429c1ad151ad5f44a6f38f97 400 Gene3D G3DSA:1.20.1090.10 187 385 1.2E-59 T 15-10-2018 C2I28_00240 90f0e53c429c1ad151ad5f44a6f38f97 400 SUPERFAMILY SSF56796 3 386 1.83E-115 T 15-10-2018 C2I28_00240 90f0e53c429c1ad151ad5f44a6f38f97 400 Gene3D G3DSA:3.40.50.1970 1 185 5.3E-56 T 15-10-2018 C2I28_16785 c8a9571303defb3cf760988e3da71589 412 Pfam PF05977 Transmembrane secretion effector 7 408 2.5E-32 T 15-10-2018 IPR010290 Transmembrane secretion effector C2I28_16785 c8a9571303defb3cf760988e3da71589 412 SUPERFAMILY SSF103473 9 392 1.23E-46 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_16785 c8a9571303defb3cf760988e3da71589 412 Gene3D G3DSA:1.20.1250.20 5 392 1.1E-37 T 15-10-2018 C2I28_23155 8462cb90514d5f374c6cd6f78c207d79 194 Pfam PF02417 Chromate transporter 5 170 2.8E-35 T 15-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.2E-11 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 1.2E-11 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 1.2E-11 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 1.2E-11 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.2E-13 T 15-10-2018 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 4.2E-13 T 15-10-2018 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 4.2E-13 T 15-10-2018 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 Gene3D G3DSA:3.50.50.60 116 228 1.6E-74 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 Gene3D G3DSA:3.50.50.60 6 291 1.6E-74 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 286 8.2E-29 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_22040 63111c9aae4d39d085240952e62b0b1c 303 SUPERFAMILY SSF51905 4 298 8.84E-34 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13890 d1896e24510c17a710f786783b3363e2 377 SUPERFAMILY SSF82771 274 362 3.92E-10 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_13890 d1896e24510c17a710f786783b3363e2 377 Pfam PF01541 GIY-YIG catalytic domain 274 361 3.0E-7 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_13890 d1896e24510c17a710f786783b3363e2 377 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 179 246 8.4E-25 T 15-10-2018 IPR018656 Domain of unknown function DUF2087 C2I28_13890 d1896e24510c17a710f786783b3363e2 377 Gene3D G3DSA:3.40.1440.10 272 373 1.2E-19 T 15-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 C2I28_13890 d1896e24510c17a710f786783b3363e2 377 SMART SM00465 273 373 7.8E-4 T 15-10-2018 IPR000305 GIY-YIG endonuclease C2I28_03530 d9f4a6f0120d1db799464f50e3c77e63 116 Gene3D G3DSA:3.30.750.24 2 116 7.2E-35 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_03530 d9f4a6f0120d1db799464f50e3c77e63 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 2.1E-48 T 15-10-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 C2I28_03530 d9f4a6f0120d1db799464f50e3c77e63 116 SUPERFAMILY SSF52091 3 113 2.35E-31 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_03530 d9f4a6f0120d1db799464f50e3c77e63 116 Pfam PF01740 STAS domain 5 109 6.0E-27 T 15-10-2018 IPR002645 STAS domain C2I28_03530 d9f4a6f0120d1db799464f50e3c77e63 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 107 2.0E-37 T 15-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 C2I28_26775 1e02e2900d50ff4110c633acd52841a5 46 SUPERFAMILY SSF47406 9 38 9.29E-9 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_26775 1e02e2900d50ff4110c633acd52841a5 46 Pfam PF08671 Anti-repressor SinI 12 34 5.7E-11 T 15-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I28_06330 f7be18faab5cad8fb6f68f462703030c 204 SMART SM00479 6 180 1.1E-21 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_06330 f7be18faab5cad8fb6f68f462703030c 204 Pfam PF00929 Exonuclease 8 171 2.0E-20 T 15-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III C2I28_06330 f7be18faab5cad8fb6f68f462703030c 204 SUPERFAMILY SSF53098 6 177 3.08E-29 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_06330 f7be18faab5cad8fb6f68f462703030c 204 Gene3D G3DSA:3.30.420.10 2 200 3.6E-40 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 199 218 3.0E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 187 3.0E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 138 3.0E-5 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 51 68 4.8E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 138 4.8E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 255 275 4.8E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 237 4.8E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 189 4.8E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 218 4.8E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 59 291 3.6E-58 T 15-10-2018 C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 186 214 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 Gene3D G3DSA:3.40.50.720 1 292 3.1E-89 T 15-10-2018 C2I28_17325 cc61cf16d2a6e14693dcfaa632e095d5 294 SUPERFAMILY SSF51735 48 291 1.42E-75 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_09545 f90dcee1c429dd74fb9ee9515f510068 310 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 126 1.1E-36 T 15-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I28_09545 f90dcee1c429dd74fb9ee9515f510068 310 SMART SM00046 3 125 1.6E-5 T 15-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I28_09545 f90dcee1c429dd74fb9ee9515f510068 310 SUPERFAMILY SSF111331 1 298 4.36E-85 T 15-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I28_09545 f90dcee1c429dd74fb9ee9515f510068 310 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 298 5.5E-113 T 15-10-2018 IPR005218 Diacylglycerol/lipid kinase C2I28_09545 f90dcee1c429dd74fb9ee9515f510068 310 Gene3D G3DSA:2.60.200.40 125 282 8.7E-90 T 15-10-2018 C2I28_09545 f90dcee1c429dd74fb9ee9515f510068 310 Gene3D G3DSA:3.40.50.10330 6 124 8.7E-90 T 15-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I28_23070 f27d1248bc7ac320f416275d74817095 93 SUPERFAMILY SSF89360 1 86 5.3E-10 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_23070 f27d1248bc7ac320f416275d74817095 93 Gene3D G3DSA:2.60.300.12 1 84 2.3E-6 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 4.0E-28 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.0E-28 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.0E-28 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 4.0E-28 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 4.0E-28 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 SUPERFAMILY SSF46609 1 91 4.58E-39 T 15-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 15-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 SUPERFAMILY SSF54719 92 201 3.01E-48 T 15-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 1.1E-34 T 15-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 Gene3D G3DSA:1.10.287.990 20 90 1.1E-32 T 15-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 2.0E-42 T 15-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 Gene3D G3DSA:2.40.500.20 91 202 3.9E-51 T 15-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_04130 86f9f0e9bbf48ad6ea32032405e6059d 202 PIRSF PIRSF000349 1 202 3.1E-86 T 15-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 C2I28_25625 4527eee642a5d1daac355282f509aa44 309 Pfam PF13739 Domain of unknown function (DUF4163) 120 211 8.8E-17 T 15-10-2018 IPR025303 Deacetylase PdaC C2I28_25625 4527eee642a5d1daac355282f509aa44 309 Gene3D G3DSA:3.30.565.40 109 226 1.8E-25 T 15-10-2018 C2I28_25625 4527eee642a5d1daac355282f509aa44 309 Pfam PF11738 Protein of unknown function (DUF3298) 230 304 8.9E-11 T 15-10-2018 IPR021729 Domain of unknown function DUF3298 C2I28_25625 4527eee642a5d1daac355282f509aa44 309 Gene3D G3DSA:3.90.640.20 228 309 3.6E-13 T 15-10-2018 IPR037126 PdaC/RsiV-like superfamily C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 4.0E-41 T 15-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 SUPERFAMILY SSF89919 2 110 3.14E-37 T 15-10-2018 IPR023799 Ribosome-binding factor A domain superfamily C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 113 2.3E-44 T 15-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 15-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 Pfam PF02033 Ribosome-binding factor A 4 107 1.3E-35 T 15-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 Gene3D G3DSA:3.30.300.20 1 116 5.6E-42 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_02310 3024bf871fd383a07c980613b4b7816c 121 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 28.928 T 15-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 Gene3D G3DSA:3.40.50.300 6 345 4.8E-108 T 15-10-2018 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 15-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 372 101.989 T 15-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 15-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 2.0E-129 T 15-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 347 1.7E-19 T 15-10-2018 IPR003395 RecF/RecN/SMC, N-terminal C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 Gene3D G3DSA:1.20.1050.90 119 311 4.8E-108 T 15-10-2018 C2I28_08030 28a3d63623d6b4d305a23121c7b676db 372 SUPERFAMILY SSF52540 2 348 3.69E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_25595 71e144f36d123c596ecd372dedbb67e0 126 Gene3D G3DSA:2.60.40.10 23 125 2.3E-5 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_25595 71e144f36d123c596ecd372dedbb67e0 126 Pfam PF13115 YtkA-like 23 106 1.5E-13 T 15-10-2018 IPR032693 YtkA-like domain C2I28_12150 9aea9547e510b0484312c13e925d29e7 318 Pfam PF00296 Luciferase-like monooxygenase 28 230 3.4E-39 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_12150 9aea9547e510b0484312c13e925d29e7 318 SUPERFAMILY SSF51679 19 311 6.54E-58 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12150 9aea9547e510b0484312c13e925d29e7 318 Gene3D G3DSA:3.20.20.30 1 317 9.2E-120 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12150 9aea9547e510b0484312c13e925d29e7 318 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 9 314 6.0E-119 T 15-10-2018 IPR020020 Luciferase-type oxidoreductase C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 SUPERFAMILY SSF50129 2 93 1.77E-34 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 Gene3D G3DSA:2.30.33.40 1 93 3.0E-38 T 15-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 4.1E-36 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.6E-32 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.6E-32 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.6E-32 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.6E-32 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 SMART SM00883 1 93 1.4E-55 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 26.851 T 15-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 C2I28_09340 0fccf10e0d55e6b168d6b2f8c010a8ff 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 15-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 C2I28_14870 d451da5f1122ebb40111090c47c073c8 442 Gene3D G3DSA:3.40.50.1010 2 150 1.2E-22 T 15-10-2018 C2I28_14870 d451da5f1122ebb40111090c47c073c8 442 Gene3D G3DSA:3.40.50.300 231 441 3.2E-68 T 15-10-2018 C2I28_14870 d451da5f1122ebb40111090c47c073c8 442 SUPERFAMILY SSF52540 22 422 3.19E-28 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14870 d451da5f1122ebb40111090c47c073c8 442 Pfam PF02562 PhoH-like protein 233 438 3.0E-54 T 15-10-2018 IPR003714 PhoH-like protein GO:0005524 C2I28_14870 d451da5f1122ebb40111090c47c073c8 442 SMART SM00670 3 135 4.0E-24 T 15-10-2018 IPR002716 PIN domain C2I28_14870 d451da5f1122ebb40111090c47c073c8 442 Pfam PF13638 PIN domain 5 147 3.6E-34 T 15-10-2018 IPR002716 PIN domain C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 Gene3D G3DSA:3.40.50.2300 1 126 3.4E-36 T 15-10-2018 C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 SMART SM00862 145 222 2.5E-21 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 Gene3D G3DSA:1.10.10.10 127 225 3.8E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 SUPERFAMILY SSF52172 1 128 3.42E-39 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 Pfam PF00072 Response regulator receiver domain 4 113 2.8E-26 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 SMART SM00448 2 113 1.3E-40 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 2.6E-22 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_17495 e014ab21809ae71702637c560ee91bb3 226 SUPERFAMILY SSF46894 121 223 4.25E-25 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_25710 e35ab2d38a0b6ece131eae7761823601 391 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 190 390 1.5E-53 T 15-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I28_25710 e35ab2d38a0b6ece131eae7761823601 391 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 4.1E-21 T 15-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I28_17390 f96a37b3414f2dbb53400c524b37efb5 365 Pfam PF03845 Spore germination protein 7 318 1.7E-30 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_17390 f96a37b3414f2dbb53400c524b37efb5 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 354 7.1E-59 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_25795 ef64e64fd7284017b0fbe097278ea2a8 235 SUPERFAMILY SSF48371 1 235 9.5E-68 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_25795 ef64e64fd7284017b0fbe097278ea2a8 235 Pfam PF08713 DNA alkylation repair enzyme 6 200 9.2E-22 T 15-10-2018 IPR014825 DNA alkylation repair enzyme C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 Gene3D G3DSA:1.25.40.10 1 290 6.8E-92 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 Pfam PF13181 Tetratricopeptide repeat 241 269 0.011 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 SUPERFAMILY SSF47413 5 64 2.7E-15 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 SMART SM00028 240 273 180.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 SMART SM00028 157 190 0.026 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 SMART SM00028 200 233 52.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 Pfam PF13424 Tetratricopeptide repeat 158 230 2.7E-7 T 15-10-2018 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 SUPERFAMILY SSF48452 133 271 1.59E-16 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 SMART SM00530 9 63 2.2E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_17640 47f9a1bd4aece86ae7c2f7767d13b787 291 Pfam PF12844 Helix-turn-helix domain 11 68 1.5E-14 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_00905 379f73ee5640b353e894938ddefda9cb 310 Pfam PF01734 Patatin-like phospholipase 6 196 9.2E-29 T 15-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I28_00905 379f73ee5640b353e894938ddefda9cb 310 SUPERFAMILY SSF52151 6 293 3.92E-39 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_00905 379f73ee5640b353e894938ddefda9cb 310 Gene3D G3DSA:3.40.1090.10 2 116 1.6E-21 T 15-10-2018 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Gene3D G3DSA:1.20.120.430 129 462 4.0E-108 T 15-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 SUPERFAMILY SSF52540 81 378 4.99E-46 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 462 34.342 T 15-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 462 3.0E-129 T 15-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Gene3D G3DSA:3.40.50.300 225 390 4.0E-108 T 15-10-2018 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 127 1.3E-40 T 15-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Pfam PF01926 50S ribosome-binding GTPase 228 339 1.1E-25 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Pfam PF12631 MnmE helical domain 130 459 3.4E-59 T 15-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 Gene3D G3DSA:3.30.1360.120 1 127 4.8E-49 T 15-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 SUPERFAMILY SSF116878 129 462 5.75E-50 T 15-10-2018 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 228 374 1.2E-28 T 15-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 PRINTS PR00449 Transforming protein P21 ras signature 225 246 6.6E-6 T 15-10-2018 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 PRINTS PR00449 Transforming protein P21 ras signature 265 287 6.6E-6 T 15-10-2018 C2I28_07990 181e18efc70784a2c1df05882485f4da 462 PRINTS PR00449 Transforming protein P21 ras signature 329 342 6.6E-6 T 15-10-2018 C2I28_14315 57ff3aaf377e69217a873146651ef611 171 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 171 26.766 T 15-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 C2I28_14315 57ff3aaf377e69217a873146651ef611 171 Pfam PF03079 ARD/ARD' family 3 168 1.3E-43 T 15-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 C2I28_14315 57ff3aaf377e69217a873146651ef611 171 SUPERFAMILY SSF51182 10 170 5.94E-31 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_14315 57ff3aaf377e69217a873146651ef611 171 Gene3D G3DSA:2.60.120.10 1 170 1.6E-58 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_15415 a07a1e0fa0a8a4496136505b11fae02d 302 Gene3D G3DSA:2.30.30.40 114 172 5.9E-6 T 15-10-2018 C2I28_15415 a07a1e0fa0a8a4496136505b11fae02d 302 Gene3D G3DSA:3.90.1720.10 173 302 2.5E-34 T 15-10-2018 C2I28_15415 a07a1e0fa0a8a4496136505b11fae02d 302 Pfam PF00877 NlpC/P60 family 195 300 4.5E-23 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_15415 a07a1e0fa0a8a4496136505b11fae02d 302 Gene3D G3DSA:2.30.30.40 1 113 1.9E-38 T 15-10-2018 C2I28_15415 a07a1e0fa0a8a4496136505b11fae02d 302 SUPERFAMILY SSF54001 176 301 7.6E-36 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_03660 3814bf5a7b4114dc8acd2753a8c3f84f 543 Pfam PF13556 PucR C-terminal helix-turn-helix domain 468 524 1.6E-17 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_03660 3814bf5a7b4114dc8acd2753a8c3f84f 543 Pfam PF07905 Purine catabolism regulatory protein-like family 18 136 1.3E-35 T 15-10-2018 IPR012914 Purine catabolism PurC-like domain C2I28_03660 3814bf5a7b4114dc8acd2753a8c3f84f 543 Gene3D G3DSA:1.10.10.2840 399 529 9.0E-15 T 15-10-2018 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 59 504 3.8E-143 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 SUPERFAMILY SSF81442 48 558 5.36E-175 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 50 75 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 3.3E-92 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 Gene3D G3DSA:1.20.210.10 34 564 7.5E-197 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17305 5eb0df614011335a1901e45a8ed82ef2 655 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 10 650 0.0 T 15-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 C2I28_22585 773b21ed0768139e05a3310ee0b8f79f 291 Gene3D G3DSA:3.30.750.24 175 291 1.0E-33 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_22585 773b21ed0768139e05a3310ee0b8f79f 291 Pfam PF01740 STAS domain 184 282 1.0E-13 T 15-10-2018 IPR002645 STAS domain C2I28_22585 773b21ed0768139e05a3310ee0b8f79f 291 SUPERFAMILY SSF52091 178 286 8.04E-16 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_10555 dcaa40cae4887ccbed0f0dc6908669c8 276 Gene3D G3DSA:3.40.630.30 1 136 1.1E-12 T 15-10-2018 C2I28_10555 dcaa40cae4887ccbed0f0dc6908669c8 276 SUPERFAMILY SSF55729 8 120 1.8E-13 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_10555 dcaa40cae4887ccbed0f0dc6908669c8 276 SUPERFAMILY SSF55729 157 272 8.97E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_10555 dcaa40cae4887ccbed0f0dc6908669c8 276 Pfam PF13673 Acetyltransferase (GNAT) domain 30 103 9.0E-7 T 15-10-2018 IPR000182 GNAT domain C2I28_10555 dcaa40cae4887ccbed0f0dc6908669c8 276 Pfam PF00583 Acetyltransferase (GNAT) family 175 263 2.5E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_10555 dcaa40cae4887ccbed0f0dc6908669c8 276 Gene3D G3DSA:3.40.630.30 147 276 3.3E-20 T 15-10-2018 C2I28_09060 a048ea96d01cd024fa74525bcfd225c5 266 SUPERFAMILY SSF161098 4 258 2.15E-46 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_09060 a048ea96d01cd024fa74525bcfd225c5 266 Gene3D G3DSA:1.10.3720.10 6 264 3.8E-44 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_27640 a7e147b632fd7f715b6ed80b87e88635 65 Pfam PF08858 IDEAL domain 25 61 5.6E-13 T 15-10-2018 IPR014957 IDEAL domain C2I28_27640 a7e147b632fd7f715b6ed80b87e88635 65 Gene3D G3DSA:4.10.810.10 10 65 5.1E-17 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_27640 a7e147b632fd7f715b6ed80b87e88635 65 SMART SM00914 25 61 2.2E-9 T 15-10-2018 IPR014957 IDEAL domain C2I28_11455 777dba2d9683cb156631797838f74a92 466 TIGRFAM TIGR00836 amt: ammonium transporter 34 421 1.3E-121 T 15-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 C2I28_11455 777dba2d9683cb156631797838f74a92 466 SUPERFAMILY SSF111352 32 402 2.48E-108 T 15-10-2018 C2I28_11455 777dba2d9683cb156631797838f74a92 466 Gene3D G3DSA:1.10.3430.10 14 432 8.0E-140 T 15-10-2018 IPR029020 Ammonium/urea transporter C2I28_11455 777dba2d9683cb156631797838f74a92 466 Pfam PF00909 Ammonium Transporter Family 37 421 1.3E-113 T 15-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 C2I28_12585 90a0d78cb3764a9b620c7b290223a3c3 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 78 6.5E-23 T 15-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 C2I28_12585 90a0d78cb3764a9b620c7b290223a3c3 284 Pfam PF01380 SIS domain 127 256 1.4E-25 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_12585 90a0d78cb3764a9b620c7b290223a3c3 284 Gene3D G3DSA:1.10.10.10 1 83 2.9E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12585 90a0d78cb3764a9b620c7b290223a3c3 284 SUPERFAMILY SSF53697 94 278 2.62E-43 T 15-10-2018 C2I28_12585 90a0d78cb3764a9b620c7b290223a3c3 284 Gene3D G3DSA:3.40.50.10490 94 282 1.2E-50 T 15-10-2018 C2I28_12585 90a0d78cb3764a9b620c7b290223a3c3 284 SUPERFAMILY SSF46689 6 79 9.32E-18 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_15015 d17129ed921cb175d45de591cf2ccd94 265 SUPERFAMILY SSF56281 35 217 1.36E-6 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_15015 d17129ed921cb175d45de591cf2ccd94 265 Gene3D G3DSA:3.60.15.10 33 264 5.6E-13 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_03845 902e39bc398e71dc76de53f576c81549 77 SUPERFAMILY SSF116842 3 68 3.79E-22 T 15-10-2018 C2I28_03845 902e39bc398e71dc76de53f576c81549 77 Pfam PF02609 Exonuclease VII small subunit 9 59 1.0E-22 T 15-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I28_03845 902e39bc398e71dc76de53f576c81549 77 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 49 5.0E-12 T 15-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I28_03845 902e39bc398e71dc76de53f576c81549 77 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 8 68 14.935 T 15-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I28_03845 902e39bc398e71dc76de53f576c81549 77 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 8 63 1.8E-24 T 15-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I28_03845 902e39bc398e71dc76de53f576c81549 77 Gene3D G3DSA:1.10.287.1040 2 77 1.1E-23 T 15-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 C2I28_03845 902e39bc398e71dc76de53f576c81549 77 PIRSF PIRSF006488 1 77 3.1E-20 T 15-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 C2I28_17825 9fb16275b8937e068c76584d20994922 189 Gene3D G3DSA:1.20.1200.10 12 189 1.4E-65 T 15-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I28_17825 9fb16275b8937e068c76584d20994922 189 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 177 3.2E-64 T 15-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I28_17825 9fb16275b8937e068c76584d20994922 189 Pfam PF01923 Cobalamin adenosyltransferase 3 165 2.0E-56 T 15-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I28_17825 9fb16275b8937e068c76584d20994922 189 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 179 9.0E-60 T 15-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I28_17825 9fb16275b8937e068c76584d20994922 189 SUPERFAMILY SSF89028 1 178 1.51E-62 T 15-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 C2I28_21165 5a5e718d54f104ac56cf8bbe5683f885 256 Gene3D G3DSA:3.40.1010.10 3 119 1.5E-42 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_21165 5a5e718d54f104ac56cf8bbe5683f885 256 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 15-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_21165 5a5e718d54f104ac56cf8bbe5683f885 256 Gene3D G3DSA:3.30.950.10 120 256 3.3E-53 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_21165 5a5e718d54f104ac56cf8bbe5683f885 256 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 241 4.5E-97 T 15-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_21165 5a5e718d54f104ac56cf8bbe5683f885 256 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 217 3.2E-48 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_21165 5a5e718d54f104ac56cf8bbe5683f885 256 SUPERFAMILY SSF53790 3 250 6.15E-84 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_04070 7fac4c60f4359dc56fd1c74fb11b0b97 68 SUPERFAMILY SSF158379 1 61 1.83E-24 T 15-10-2018 IPR023164 YqgQ-like superfamily C2I28_04070 7fac4c60f4359dc56fd1c74fb11b0b97 68 Gene3D G3DSA:1.10.287.760 1 68 1.4E-30 T 15-10-2018 IPR023164 YqgQ-like superfamily C2I28_04070 7fac4c60f4359dc56fd1c74fb11b0b97 68 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 8.0E-30 T 15-10-2018 IPR009256 Protein of unknown function DUF910 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Pfam PF03461 TRCF domain 1025 1117 5.4E-26 T 15-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1097 0.0 T 15-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Pfam PF00270 DEAD/DEAH box helicase 627 784 4.5E-18 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SUPERFAMILY SSF52540 543 803 1.7E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SMART SM00487 620 810 6.9E-35 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SUPERFAMILY SSF52540 15 368 4.43E-85 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Gene3D G3DSA:3.30.2060.10 140 225 2.8E-62 T 15-10-2018 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Gene3D G3DSA:3.90.1150.50 1020 1176 8.8E-42 T 15-10-2018 IPR037235 TRCF-like, C-terminal domain C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Gene3D G3DSA:3.40.50.300 498 1008 9.3E-247 T 15-10-2018 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 30 1149 28.693 T 15-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SUPERFAMILY SSF143517 1014 1166 1.19E-34 T 15-10-2018 IPR037235 TRCF-like, C-terminal domain C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SUPERFAMILY SSF52540 802 1009 5.09E-48 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SMART SM00490 846 930 2.8E-17 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SUPERFAMILY SSF52540 377 490 1.27E-25 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Pfam PF02559 CarD-like/TRCF domain 500 595 3.0E-32 T 15-10-2018 IPR003711 CarD-like/TRCF domain C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SUPERFAMILY SSF141259 490 568 5.23E-26 T 15-10-2018 IPR036101 CarD-like/TRCF domain superfamily C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SMART SM00982 1024 1124 1.7E-35 T 15-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Gene3D G3DSA:3.40.50.11180 35 326 2.8E-62 T 15-10-2018 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Pfam PF00271 Helicase conserved C-terminal domain 829 929 2.5E-15 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Gene3D G3DSA:3.40.50.300 562 801 9.3E-247 T 15-10-2018 C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 SMART SM01058 499 596 7.2E-51 T 15-10-2018 IPR003711 CarD-like/TRCF domain C2I28_08380 e58d1c9f3a3c54fac7575c1ad12d3376 1176 Gene3D G3DSA:2.30.30.840 503 561 9.3E-247 T 15-10-2018 C2I28_01615 5a264d2563197b0ec4d3f12221ed10b6 272 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 39 263 2.6E-49 T 15-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I28_01615 5a264d2563197b0ec4d3f12221ed10b6 272 Gene3D G3DSA:3.20.20.190 20 272 5.2E-91 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_01615 5a264d2563197b0ec4d3f12221ed10b6 272 SUPERFAMILY SSF51695 33 269 4.97E-73 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 Pfam PF01544 CorA-like Mg2+ transporter protein 28 309 3.9E-74 T 15-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 2 313 1.1E-83 T 15-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 SUPERFAMILY SSF143865 2 246 4.05E-59 T 15-10-2018 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 SUPERFAMILY SSF144083 248 310 7.85E-19 T 15-10-2018 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 Gene3D G3DSA:1.20.58.340 237 313 1.0E-24 T 15-10-2018 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 Gene3D G3DSA:3.30.460.20 1 123 6.4E-35 T 15-10-2018 C2I28_09765 c8a1d62600b3f18391c1f528e59a3ff0 321 Gene3D G3DSA:1.20.58.340 124 234 6.6E-27 T 15-10-2018 C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 Pfam PF00156 Phosphoribosyl transferase domain 281 381 1.2E-7 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 PIRSF PIRSF000485 8 469 1.9E-189 T 15-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 Pfam PF13522 Glutamine amidotransferase domain 72 204 1.4E-22 T 15-10-2018 C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 SUPERFAMILY SSF53271 246 463 2.75E-74 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 Gene3D G3DSA:3.40.50.2020 270 434 1.3E-171 T 15-10-2018 C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 454 47.559 T 15-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 SUPERFAMILY SSF56235 12 238 3.26E-72 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 Gene3D G3DSA:3.60.20.10 12 456 1.3E-171 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_09460 0d7b43be709ed502f5241abca05151b1 471 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 455 8.5E-172 T 15-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 C2I28_05390 2633afb84f104e62a9d92a252d57f246 158 Gene3D G3DSA:3.10.129.10 10 154 2.9E-29 T 15-10-2018 C2I28_05390 2633afb84f104e62a9d92a252d57f246 158 Pfam PF01575 MaoC like domain 25 125 2.0E-10 T 15-10-2018 IPR002539 MaoC-like dehydratase domain C2I28_05390 2633afb84f104e62a9d92a252d57f246 158 SUPERFAMILY SSF54637 9 146 4.19E-27 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_07035 b86ca58a2499bb09ef6aa658d98c0fef 104 Gene3D G3DSA:1.10.760.10 34 104 2.0E-28 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_07035 b86ca58a2499bb09ef6aa658d98c0fef 104 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 34 100 3.1E-13 T 15-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_07035 b86ca58a2499bb09ef6aa658d98c0fef 104 PIRSF PIRSF000025 1 104 2.0E-30 T 15-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 C2I28_07035 b86ca58a2499bb09ef6aa658d98c0fef 104 SUPERFAMILY SSF46626 4 102 2.29E-16 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_02915 4aad2ebfed0d5ddb132a56b698c712b6 84 Pfam PF05239 PRC-barrel domain 3 75 6.3E-16 T 15-10-2018 IPR027275 PRC-barrel domain C2I28_02915 4aad2ebfed0d5ddb132a56b698c712b6 84 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 73 4.0E-26 T 15-10-2018 IPR014238 Sporulation protein YlmC/YmxH C2I28_02915 4aad2ebfed0d5ddb132a56b698c712b6 84 SUPERFAMILY SSF50346 1 74 8.37E-15 T 15-10-2018 IPR011033 PRC-barrel-like superfamily C2I28_02915 4aad2ebfed0d5ddb132a56b698c712b6 84 Gene3D G3DSA:2.30.30.240 1 76 1.8E-12 T 15-10-2018 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 SUPERFAMILY SSF58104 323 658 4.58E-73 T 15-10-2018 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Pfam PF00672 HAMP domain 304 351 1.6E-11 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 SMART SM00283 384 659 1.9E-80 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 610 4.1E-49 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Pfam PF02743 Cache domain 43 265 1.5E-28 T 15-10-2018 IPR033479 Double Cache domain 1 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Gene3D G3DSA:1.10.8.500 303 354 3.7E-10 T 15-10-2018 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 SUPERFAMILY SSF103190 100 193 1.96E-10 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Gene3D G3DSA:1.10.287.950 355 659 6.4E-71 T 15-10-2018 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 SMART SM00304 303 355 5.5E-12 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Gene3D G3DSA:3.30.450.20 72 183 2.3E-37 T 15-10-2018 C2I28_20380 68303aad35249b7437940d2b52f515fd 660 Gene3D G3DSA:3.30.450.20 60 271 2.3E-37 T 15-10-2018 C2I28_03935 ae329bccef0dc61bcf020c049d264511 178 Pfam PF11085 Conserved membrane protein YqhR 9 169 1.3E-65 T 15-10-2018 IPR024563 Uncharacterised protein family YqhR C2I28_03935 ae329bccef0dc61bcf020c049d264511 178 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 14 165 2.0E-31 T 15-10-2018 IPR024563 Uncharacterised protein family YqhR C2I28_06325 f36c05ed4d198b07e558359312c48acd 126 SUPERFAMILY SSF141251 2 124 5.23E-48 T 15-10-2018 IPR038080 Kinase associated protein B superfamily C2I28_06325 f36c05ed4d198b07e558359312c48acd 126 Pfam PF08810 Kinase associated protein B 13 123 2.9E-45 T 15-10-2018 IPR014916 Kinase associated protein B C2I28_06325 f36c05ed4d198b07e558359312c48acd 126 Gene3D G3DSA:2.30.30.430 1 125 1.4E-50 T 15-10-2018 IPR038080 Kinase associated protein B superfamily C2I28_06325 f36c05ed4d198b07e558359312c48acd 126 SMART SM01298 13 125 5.2E-58 T 15-10-2018 IPR014916 Kinase associated protein B C2I28_23445 9998f93d4a2b2869b73dde10499feaae 87 Pfam PF04226 Transglycosylase associated protein 33 78 1.7E-10 T 15-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 C2I28_25290 b50f7a7d31ffea6317737d93bfc71f92 129 SUPERFAMILY SSF46955 3 117 1.83E-30 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_25290 b50f7a7d31ffea6317737d93bfc71f92 129 Pfam PF13411 MerR HTH family regulatory protein 3 69 2.0E-18 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_25290 b50f7a7d31ffea6317737d93bfc71f92 129 Gene3D G3DSA:1.10.1660.10 1 129 7.7E-34 T 15-10-2018 C2I28_25290 b50f7a7d31ffea6317737d93bfc71f92 129 SMART SM00422 3 72 9.6E-22 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 SMART SM00382 176 320 1.3E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_13485 06751d3c8b738c14275458048b4222ee 464 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 243 258 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 180 193 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 Gene3D G3DSA:1.10.8.60 329 405 3.4E-22 T 15-10-2018 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 Pfam PF00158 Sigma-54 interaction domain 156 323 1.5E-64 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 SUPERFAMILY SSF46689 369 462 1.34E-7 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 Gene3D G3DSA:3.40.50.300 145 328 1.3E-62 T 15-10-2018 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 Gene3D G3DSA:1.10.10.60 406 463 1.7E-5 T 15-10-2018 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 Pfam PF13426 PAS domain 28 121 3.1E-6 T 15-10-2018 IPR000014 PAS domain C2I28_13485 06751d3c8b738c14275458048b4222ee 464 SUPERFAMILY SSF55785 15 114 1.52E-7 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_13485 06751d3c8b738c14275458048b4222ee 464 Gene3D G3DSA:3.30.450.20 7 139 7.5E-12 T 15-10-2018 C2I28_13485 06751d3c8b738c14275458048b4222ee 464 SUPERFAMILY SSF52540 156 399 2.13E-67 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20415 b56e43179c41249f9000fa488cd3a3da 269 Gene3D G3DSA:3.40.50.10090 13 257 5.2E-74 T 15-10-2018 C2I28_20415 b56e43179c41249f9000fa488cd3a3da 269 Gene3D G3DSA:3.40.50.10090 37 173 5.2E-74 T 15-10-2018 C2I28_20415 b56e43179c41249f9000fa488cd3a3da 269 SUPERFAMILY SSF69618 6 267 1.44E-54 T 15-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_20415 b56e43179c41249f9000fa488cd3a3da 269 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 256 2.6E-39 T 15-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 C2I28_25990 b7cfbf5bda540585cb62e59b88bd660a 220 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 7 204 1.1E-49 T 15-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I28_25990 b7cfbf5bda540585cb62e59b88bd660a 220 Pfam PF01081 KDPG and KHG aldolase 8 185 3.9E-37 T 15-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I28_25990 b7cfbf5bda540585cb62e59b88bd660a 220 Gene3D G3DSA:3.20.20.70 2 217 3.1E-71 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_25990 b7cfbf5bda540585cb62e59b88bd660a 220 SUPERFAMILY SSF51569 3 207 4.4E-59 T 15-10-2018 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 236 16.333 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 ProSitePatterns PS01218 TatC family signature. 151 170 - T 15-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 218 2.7E-59 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 223 9.7E-72 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 99 125 2.6E-39 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 81 99 2.6E-39 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 2.6E-39 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_09325 604e859466d6af9edbcda7256cb3d65e 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 151 179 2.6E-39 T 15-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 C2I28_00425 169da52d3611df6709fb4f22a57d1a35 112 Pfam PF11122 Inner spore coat protein D 47 106 6.8E-10 T 15-10-2018 IPR020108 Spore coat protein CotD C2I28_00425 169da52d3611df6709fb4f22a57d1a35 112 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 42 100 1.0E-5 T 15-10-2018 IPR020108 Spore coat protein CotD C2I28_01530 d34fccf105d26c8f024b45e89da0f3d6 132 PRINTS PR01438 Universal stress protein signature 92 104 2.5E-20 T 15-10-2018 IPR006015 Universal stress protein A C2I28_01530 d34fccf105d26c8f024b45e89da0f3d6 132 PRINTS PR01438 Universal stress protein signature 110 132 2.5E-20 T 15-10-2018 IPR006015 Universal stress protein A C2I28_01530 d34fccf105d26c8f024b45e89da0f3d6 132 PRINTS PR01438 Universal stress protein signature 2 20 2.5E-20 T 15-10-2018 IPR006015 Universal stress protein A C2I28_01530 d34fccf105d26c8f024b45e89da0f3d6 132 Gene3D G3DSA:3.40.50.620 1 132 3.0E-30 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_01530 d34fccf105d26c8f024b45e89da0f3d6 132 Pfam PF00582 Universal stress protein family 1 132 3.1E-26 T 15-10-2018 IPR006016 UspA C2I28_01530 d34fccf105d26c8f024b45e89da0f3d6 132 SUPERFAMILY SSF52402 1 132 3.85E-28 T 15-10-2018 C2I28_20220 ff88878d313bef61f245f6f49ac9e404 271 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 11 237 1.0E-61 T 15-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 C2I28_20220 ff88878d313bef61f245f6f49ac9e404 271 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 246 43.065 T 15-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 Gene3D G3DSA:3.30.70.141 1 149 1.0E-63 T 15-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 Pfam PF00334 Nucleoside diphosphate kinase 3 136 4.2E-59 T 15-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 4.5E-52 T 15-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 113 132 4.5E-52 T 15-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 4.5E-52 T 15-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 90 106 4.5E-52 T 15-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 4.5E-52 T 15-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 SMART SM00562 2 139 6.8E-88 T 15-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 37.25 T 15-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 113 121 - T 15-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 C2I28_03210 4e981f98a3cdc845c189ddd15f9e373b 149 SUPERFAMILY SSF54919 2 149 4.98E-60 T 15-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 Pfam PF01593 Flavin containing amine oxidoreductase 10 465 5.8E-31 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 Gene3D G3DSA:3.90.660.50 83 403 4.8E-31 T 15-10-2018 C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 6.0E-5 T 15-10-2018 C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 6.0E-5 T 15-10-2018 C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 4 480 1.3E-105 T 15-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 SUPERFAMILY SSF51905 1 474 8.7E-61 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11440 9225d4cbfab384bb6a78974f18365cad 485 Gene3D G3DSA:3.50.50.60 5 305 4.8E-31 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_21155 9b4a23ee08bba7badeda7d82a877c4bf 189 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 12 189 1.4E-53 T 15-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 C2I28_21155 9b4a23ee08bba7badeda7d82a877c4bf 189 Gene3D G3DSA:3.40.50.300 2 189 2.0E-64 T 15-10-2018 C2I28_21155 9b4a23ee08bba7badeda7d82a877c4bf 189 SUPERFAMILY SSF52540 5 189 3.14E-57 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21155 9b4a23ee08bba7badeda7d82a877c4bf 189 PIRSF PIRSF015617 1 189 7.8E-69 T 15-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 C2I28_21155 9b4a23ee08bba7badeda7d82a877c4bf 189 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 15 189 7.8E-62 T 15-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 SUPERFAMILY SSF51621 17 922 6.28E-296 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 Pfam PF00311 Phosphoenolpyruvate carboxylase 143 922 7.7E-296 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 9 922 17.934 T 15-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 568 588 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 748 774 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 610 639 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 200 216 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 259 274 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 402 422 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 147 160 3.4E-59 T 15-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_12240 3ad007cd3b82179034ebf6faccf1ab36 922 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 148 159 - T 15-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 C2I28_08095 753ec7ece305d268197740f51014377a 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 2.2E-36 T 15-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 C2I28_08095 753ec7ece305d268197740f51014377a 425 SUPERFAMILY SSF55681 117 422 1.53E-106 T 15-10-2018 C2I28_08095 753ec7ece305d268197740f51014377a 425 Gene3D G3DSA:3.30.930.10 106 425 4.2E-130 T 15-10-2018 C2I28_08095 753ec7ece305d268197740f51014377a 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 4.1E-33 T 15-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 C2I28_08095 753ec7ece305d268197740f51014377a 425 SUPERFAMILY SSF46589 1 113 8.89E-32 T 15-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 C2I28_08095 753ec7ece305d268197740f51014377a 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.33 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 Gene3D G3DSA:1.10.287.40 1 105 1.8E-26 T 15-10-2018 C2I28_08095 753ec7ece305d268197740f51014377a 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 3.2E-184 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 6.6E-31 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 6.6E-31 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 6.6E-31 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 6.6E-31 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 6.6E-31 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_08095 753ec7ece305d268197740f51014377a 425 PIRSF PIRSF001529 1 425 3.3E-195 T 15-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 2.2E-8 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.2E-8 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.2E-8 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 Gene3D G3DSA:3.40.50.1820 143 229 3.5E-11 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 Gene3D G3DSA:3.40.50.1820 2 142 1.4E-37 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 Pfam PF00561 alpha/beta hydrolase fold 26 133 2.6E-20 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16290 b96f5d3952b5888da2a8d542cbe8228c 229 SUPERFAMILY SSF53474 7 228 2.62E-50 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 3.9E-15 T 15-10-2018 C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 Pfam PF01037 Lrp/AsnC ligand binding domain 89 135 3.9E-7 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 SUPERFAMILY SSF54909 64 135 5.36E-7 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 SMART SM00344 2 109 9.1E-26 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 Gene3D G3DSA:3.30.70.920 54 136 7.5E-14 T 15-10-2018 C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.0E-11 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.0E-11 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.0E-11 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 SUPERFAMILY SSF46785 1 62 2.69E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_10640 ccc87544dd6657bb547fe9ef195d02f0 136 Gene3D G3DSA:1.10.10.10 1 53 8.8E-19 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06230 f9107a633cd6b371f73c7343bb4fdcbf 134 Pfam PF08868 YugN-like family 3 132 4.7E-55 T 15-10-2018 IPR014967 Uncharacterised protein family, YugN-like C2I28_06230 f9107a633cd6b371f73c7343bb4fdcbf 134 Gene3D G3DSA:3.30.310.100 4 106 1.2E-29 T 15-10-2018 IPR036491 YugN-like superfamily C2I28_06230 f9107a633cd6b371f73c7343bb4fdcbf 134 SUPERFAMILY SSF160755 1 132 3.92E-37 T 15-10-2018 IPR036491 YugN-like superfamily C2I28_24265 8802ad7e15f896489d58372524da9e16 284 Pfam PF13185 GAF domain 15 153 6.3E-7 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_24265 8802ad7e15f896489d58372524da9e16 284 SUPERFAMILY SSF55781 15 155 4.8E-13 T 15-10-2018 C2I28_24265 8802ad7e15f896489d58372524da9e16 284 SMART SM00065 14 162 1.4E-5 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_24265 8802ad7e15f896489d58372524da9e16 284 Gene3D G3DSA:3.30.750.24 164 279 1.8E-24 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_24265 8802ad7e15f896489d58372524da9e16 284 SUPERFAMILY SSF52091 168 275 6.67E-7 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_24265 8802ad7e15f896489d58372524da9e16 284 Gene3D G3DSA:3.30.450.40 13 160 7.3E-11 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_22055 eb40b18abd30d07419b84eef3790b076 356 Pfam PF00296 Luciferase-like monooxygenase 1 303 4.7E-70 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_22055 eb40b18abd30d07419b84eef3790b076 356 Gene3D G3DSA:3.20.20.30 1 341 1.8E-85 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_22055 eb40b18abd30d07419b84eef3790b076 356 SUPERFAMILY SSF51679 1 336 3.93E-81 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12410 3ce0a6a1bb9f7cc1c2755b512d787ee1 60 Pfam PF08863 YolD-like protein 1 59 1.2E-9 T 15-10-2018 IPR014962 YolD-like protein C2I28_06690 793fb1ecc32f285954d58570803da277 451 Gene3D G3DSA:1.10.287.130 179 299 1.7E-26 T 15-10-2018 C2I28_06690 793fb1ecc32f285954d58570803da277 451 SMART SM00304 175 229 7.7E-7 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_06690 793fb1ecc32f285954d58570803da277 451 SMART SM00387 339 449 6.2E-39 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_06690 793fb1ecc32f285954d58570803da277 451 Gene3D G3DSA:3.30.565.10 300 450 5.5E-44 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_06690 793fb1ecc32f285954d58570803da277 451 SUPERFAMILY SSF55874 288 447 4.98E-42 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_06690 793fb1ecc32f285954d58570803da277 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 3.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_06690 793fb1ecc32f285954d58570803da277 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 446 3.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_06690 793fb1ecc32f285954d58570803da277 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 3.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_06690 793fb1ecc32f285954d58570803da277 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 3.4E-17 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_06690 793fb1ecc32f285954d58570803da277 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 447 1.1E-27 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_06690 793fb1ecc32f285954d58570803da277 451 SUPERFAMILY SSF158472 175 228 6.93E-6 T 15-10-2018 C2I28_06690 793fb1ecc32f285954d58570803da277 451 SUPERFAMILY SSF47384 213 297 2.94E-19 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_06690 793fb1ecc32f285954d58570803da277 451 SMART SM00388 230 297 1.1E-17 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_06690 793fb1ecc32f285954d58570803da277 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 295 7.0E-15 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_22775 4f2a67b78a40b93e0f0e93b95d119239 184 Pfam PF04229 GrpB protein 7 163 5.2E-55 T 15-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I28_22775 4f2a67b78a40b93e0f0e93b95d119239 184 SUPERFAMILY SSF81301 9 171 5.56E-55 T 15-10-2018 C2I28_22775 4f2a67b78a40b93e0f0e93b95d119239 184 Gene3D G3DSA:3.30.460.10 3 172 1.8E-59 T 15-10-2018 C2I28_19960 7fba8e1173c77965d03c79819f810367 248 SUPERFAMILY SSF56281 2 243 5.9E-47 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_19960 7fba8e1173c77965d03c79819f810367 248 SMART SM00849 22 224 7.6E-28 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_19960 7fba8e1173c77965d03c79819f810367 248 Gene3D G3DSA:3.60.15.10 5 248 1.9E-45 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_19960 7fba8e1173c77965d03c79819f810367 248 Pfam PF00753 Metallo-beta-lactamase superfamily 24 203 1.2E-23 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_23470 f26566c05727df01b14879d300d2bd12 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 15-10-2018 IPR033135 ClpP, histidine active site C2I28_23470 f26566c05727df01b14879d300d2bd12 193 SUPERFAMILY SSF52096 10 190 4.21E-68 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_23470 f26566c05727df01b14879d300d2bd12 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 1.4E-50 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 1.4E-50 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 1.4E-50 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 1.4E-50 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 1.4E-50 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 15-10-2018 IPR018215 ClpP, Ser active site C2I28_23470 f26566c05727df01b14879d300d2bd12 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 6.8E-100 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 Pfam PF00574 Clp protease 13 191 5.7E-83 T 15-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA C2I28_23470 f26566c05727df01b14879d300d2bd12 193 Gene3D G3DSA:3.90.226.10 1 193 3.4E-80 T 15-10-2018 C2I28_23470 f26566c05727df01b14879d300d2bd12 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 42.279 T 15-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 C2I28_04250 a54bcc69a02186e1614e34ce5011bedd 119 PIRSF PIRSF000025 1 119 3.3E-40 T 15-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 C2I28_04250 a54bcc69a02186e1614e34ce5011bedd 119 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 49 115 6.7E-14 T 15-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_04250 a54bcc69a02186e1614e34ce5011bedd 119 SUPERFAMILY SSF46626 7 117 6.98E-17 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_04250 a54bcc69a02186e1614e34ce5011bedd 119 Gene3D G3DSA:1.10.760.10 49 119 8.6E-25 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_14250 8c423ab8d7a5e12e038e0f9e0a2f16ef 239 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 62.91 T 15-10-2018 IPR022822 Lactate utilization protein A GO:0006089 C2I28_14250 8c423ab8d7a5e12e038e0f9e0a2f16ef 239 Pfam PF02754 Cysteine-rich domain 3 84 1.2E-16 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_14250 8c423ab8d7a5e12e038e0f9e0a2f16ef 239 Pfam PF02754 Cysteine-rich domain 132 215 6.8E-14 T 15-10-2018 IPR004017 Cysteine-rich domain C2I28_27445 a4b229ecd2f9e94754427b7260e3a7c9 243 Pfam PF00535 Glycosyl transferase family 2 6 122 4.4E-28 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_27445 a4b229ecd2f9e94754427b7260e3a7c9 243 Gene3D G3DSA:3.90.550.10 1 240 6.8E-59 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_27445 a4b229ecd2f9e94754427b7260e3a7c9 243 SUPERFAMILY SSF53448 3 227 4.5E-58 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_10155 59233e654fa4903ced4d1ee1adf5a4a8 156 SUPERFAMILY SSF52833 4 153 2.86E-54 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_10155 59233e654fa4903ced4d1ee1adf5a4a8 156 PIRSF PIRSF000239 1 153 1.9E-30 T 15-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_10155 59233e654fa4903ced4d1ee1adf5a4a8 156 Pfam PF00578 AhpC/TSA family 5 132 6.4E-41 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_10155 59233e654fa4903ced4d1ee1adf5a4a8 156 Gene3D G3DSA:3.40.30.10 1 155 1.7E-54 T 15-10-2018 C2I28_01610 a5a826e9e242684e558602bd9527dc47 207 SUPERFAMILY SSF63817 53 194 8.76E-19 T 15-10-2018 IPR023365 Sortase domain superfamily C2I28_01610 a5a826e9e242684e558602bd9527dc47 207 Pfam PF04203 Sortase family 61 197 5.3E-19 T 15-10-2018 IPR005754 Sortase family C2I28_01610 a5a826e9e242684e558602bd9527dc47 207 Gene3D G3DSA:2.40.260.10 20 206 6.9E-29 T 15-10-2018 IPR023365 Sortase domain superfamily C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 Pfam PF07883 Cupin domain 120 177 6.1E-8 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 Gene3D G3DSA:1.10.260.40 1 79 1.4E-17 T 15-10-2018 C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 SUPERFAMILY SSF51182 74 182 4.11E-17 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 SUPERFAMILY SSF47413 5 72 3.22E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 SMART SM00530 13 68 2.4E-14 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 Pfam PF01381 Helix-turn-helix 14 68 3.2E-15 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_20635 018755fd9059c4b55c6a042a5cd0240d 185 Gene3D G3DSA:2.60.120.10 92 185 1.2E-21 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_22375 cd381d40dc2bd1489c63dcf2ea39a9d5 276 Gene3D G3DSA:3.30.70.120 188 263 1.2E-26 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_22375 cd381d40dc2bd1489c63dcf2ea39a9d5 276 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 210 4.0E-61 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_22375 cd381d40dc2bd1489c63dcf2ea39a9d5 276 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 7.5E-23 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_22375 cd381d40dc2bd1489c63dcf2ea39a9d5 276 PIRSF PIRSF006483 1 276 5.2E-83 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_25800 c0d133b9589c21832dbd0fb8365e3e34 123 SUPERFAMILY SSF159888 1 123 8.24E-41 T 15-10-2018 C2I28_25800 c0d133b9589c21832dbd0fb8365e3e34 123 Gene3D G3DSA:1.10.10.810 1 115 1.5E-51 T 15-10-2018 C2I28_25800 c0d133b9589c21832dbd0fb8365e3e34 123 Pfam PF08818 Domain of unknown function (DU1801) 17 109 1.4E-12 T 15-10-2018 IPR014922 Domain of unknown function DUF1801 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 180 190 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 SUPERFAMILY SSF52025 340 414 1.44E-6 T 15-10-2018 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 465 475 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 Gene3D G3DSA:3.40.50.200 96 306 4.9E-48 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 Pfam PF06280 Fn3-like domain 576 628 6.8E-6 T 15-10-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 136 147 - T 15-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 Gene3D G3DSA:3.50.30.30 307 410 1.9E-9 T 15-10-2018 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 Gene3D G3DSA:3.40.50.200 411 532 5.8E-34 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 SUPERFAMILY SSF52743 123 529 2.23E-84 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 Pfam PF00082 Subtilase family 131 519 1.6E-66 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 Pfam PF02225 PA domain 339 404 4.8E-8 T 15-10-2018 IPR003137 PA domain C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 PRINTS PR00723 Subtilisin serine protease family (S8) signature 176 189 3.1E-20 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 PRINTS PR00723 Subtilisin serine protease family (S8) signature 464 480 3.1E-20 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_07360 aab6983e4cb68626a451f451559ed80c 730 PRINTS PR00723 Subtilisin serine protease family (S8) signature 131 150 3.1E-20 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_19620 7727ea7b3851a5c0cba00492e9f457c9 284 Gene3D G3DSA:3.30.750.24 163 283 7.9E-33 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_19620 7727ea7b3851a5c0cba00492e9f457c9 284 Pfam PF01740 STAS domain 170 270 5.4E-11 T 15-10-2018 IPR002645 STAS domain C2I28_19620 7727ea7b3851a5c0cba00492e9f457c9 284 SUPERFAMILY SSF52091 168 276 6.67E-17 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09725 be600f019dfbbc2878ad0464045ab4ae 174 Pfam PF01965 DJ-1/PfpI family 6 167 1.6E-45 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_09725 be600f019dfbbc2878ad0464045ab4ae 174 Gene3D G3DSA:3.40.50.880 2 174 6.3E-51 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09725 be600f019dfbbc2878ad0464045ab4ae 174 SUPERFAMILY SSF52317 6 173 2.21E-48 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_09725 be600f019dfbbc2878ad0464045ab4ae 174 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 8 171 2.5E-50 T 15-10-2018 IPR006286 Deglycase PfpI C2I28_19625 f308cebe6b0351ac47d235bcc6927688 66 Pfam PF11755 Protein of unknown function (DUF3311) 7 61 4.0E-20 T 15-10-2018 IPR021741 Protein of unknown function DUF3311 C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 SUPERFAMILY SSF75217 67 243 2.81E-49 T 15-10-2018 IPR029028 Alpha/beta knot methyltransferases C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 Gene3D G3DSA:3.30.1330.30 1 73 9.1E-12 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 Pfam PF00588 SpoU rRNA Methylase family 96 236 2.4E-38 T 15-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 242 3.5E-82 T 15-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 SMART SM00967 5 79 9.3E-22 T 15-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 Gene3D G3DSA:3.40.1280.10 74 243 3.5E-56 T 15-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 SUPERFAMILY SSF55315 3 76 4.59E-18 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_08590 c276182a8d35574f1b41d7b24920ef1c 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 3.0E-22 T 15-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 C2I28_04795 386f7509f0532dcd9d6727e729501a5e 426 Gene3D G3DSA:3.10.350.10 2 58 3.0E-17 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_04795 386f7509f0532dcd9d6727e729501a5e 426 SMART SM00257 5 50 2.2E-18 T 15-10-2018 IPR018392 LysM domain C2I28_04795 386f7509f0532dcd9d6727e729501a5e 426 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 8 51 3.1E-27 T 15-10-2018 IPR014248 Spore coat assembly protein SafA C2I28_04795 386f7509f0532dcd9d6727e729501a5e 426 SUPERFAMILY SSF54106 4 50 3.27E-12 T 15-10-2018 C2I28_04795 386f7509f0532dcd9d6727e729501a5e 426 Pfam PF01476 LysM domain 6 50 3.1E-16 T 15-10-2018 IPR018392 LysM domain C2I28_18315 4140842460d55031b6fea9e186aa1c8e 466 SUPERFAMILY SSF53474 178 390 3.83E-10 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_18315 4140842460d55031b6fea9e186aa1c8e 466 Pfam PF07519 Tannase and feruloyl esterase 69 189 2.9E-5 T 15-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 Pfam PF00232 Glycosyl hydrolase family 1 3 476 3.4E-136 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 15-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 373 381 - T 15-10-2018 IPR018120 Glycoside hydrolase family 1, active site C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 2.9E-18 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 394 405 2.9E-18 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 2.9E-18 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 2.9E-18 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 2.9E-18 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 SUPERFAMILY SSF51445 2 473 2.26E-164 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_24695 89dcc5ee3bdc7fbd2fe8eff1b5328e52 479 Gene3D G3DSA:3.20.20.80 1 479 3.7E-165 T 15-10-2018 C2I28_02885 a2973dc40b252078916291a931f2f1ab 164 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.7E-18 T 15-10-2018 IPR019933 DivIVA domain C2I28_02885 a2973dc40b252078916291a931f2f1ab 164 Pfam PF05103 DivIVA protein 3 133 5.9E-51 T 15-10-2018 IPR007793 DivIVA family C2I28_09605 3de2c2a59bbfe0d50ee5f2bb5b06a24b 273 SMART SM00422 5 75 6.0E-15 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_09605 3de2c2a59bbfe0d50ee5f2bb5b06a24b 273 Gene3D G3DSA:1.10.1660.10 1 117 1.4E-24 T 15-10-2018 C2I28_09605 3de2c2a59bbfe0d50ee5f2bb5b06a24b 273 SUPERFAMILY SSF46955 5 108 2.75E-25 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_09605 3de2c2a59bbfe0d50ee5f2bb5b06a24b 273 Pfam PF13411 MerR HTH family regulatory protein 5 73 4.6E-14 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_09605 3de2c2a59bbfe0d50ee5f2bb5b06a24b 273 SUPERFAMILY SSF55136 123 271 3.66E-22 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_09605 3de2c2a59bbfe0d50ee5f2bb5b06a24b 273 Gene3D G3DSA:3.20.80.10 120 273 1.2E-15 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_01555 bc219298d13f477dceedec2082692243 478 PIRSF PIRSF005690 2 478 6.1E-163 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_01555 bc219298d13f477dceedec2082692243 478 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 19 470 2.9E-158 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_07945 14055660f49ae88eba88216a5de71799 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 60 4.7E-31 T 15-10-2018 IPR009296 Protein of unknown function DUF951 C2I28_07945 14055660f49ae88eba88216a5de71799 65 PIRSF PIRSF037263 1 65 2.9E-36 T 15-10-2018 IPR009296 Protein of unknown function DUF951 C2I28_22355 e6fa39f25698f587fb678cdc9912fa8c 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 260 1.6E-24 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_22355 e6fa39f25698f587fb678cdc9912fa8c 268 Gene3D G3DSA:1.10.3720.10 59 264 5.9E-18 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_22355 e6fa39f25698f587fb678cdc9912fa8c 268 SUPERFAMILY SSF161098 63 251 2.35E-21 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_22380 2ed6bff6c71b5dfa9e953ebb40f69985 186 Gene3D G3DSA:1.25.40.10 31 185 1.6E-13 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_22380 2ed6bff6c71b5dfa9e953ebb40f69985 186 SUPERFAMILY SSF48452 41 160 4.93E-10 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_15330 a6e3d3b296daf3c7933fcbf3e0547801 153 Pfam PF02681 Divergent PAP2 family 2 141 1.2E-42 T 15-10-2018 IPR003832 Protein of unknown function DUF212 C2I28_16655 fcd45900479817a43f862e0d2e5003a0 272 SUPERFAMILY SSF50182 98 156 4.9E-8 T 15-10-2018 IPR010920 LSM domain superfamily C2I28_16655 fcd45900479817a43f862e0d2e5003a0 272 Pfam PF00924 Mechanosensitive ion channel 56 198 1.8E-20 T 15-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I28_16655 fcd45900479817a43f862e0d2e5003a0 272 Gene3D G3DSA:2.30.30.60 113 163 7.4E-11 T 15-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I28_09125 24fcb51c895adce6c022f64ec0323f49 200 Pfam PF01694 Rhomboid family 54 195 7.0E-36 T 15-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 C2I28_09125 24fcb51c895adce6c022f64ec0323f49 200 Gene3D G3DSA:1.20.1540.10 9 199 1.1E-43 T 15-10-2018 IPR035952 Rhomboid-like superfamily C2I28_09125 24fcb51c895adce6c022f64ec0323f49 200 SUPERFAMILY SSF144091 11 196 2.49E-42 T 15-10-2018 C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 Pfam PF00072 Response regulator receiver domain 5 114 6.2E-31 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 SMART SM00448 3 113 3.8E-43 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 Gene3D G3DSA:1.10.10.10 129 226 7.8E-36 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 SMART SM00862 150 226 3.3E-27 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 SUPERFAMILY SSF52172 4 178 3.92E-42 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 Gene3D G3DSA:3.40.50.2300 1 128 4.6E-39 T 15-10-2018 C2I28_18770 4a4e1fe3ec1959e88a5ce0a19890ea23 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 6.8E-29 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_21655 1aba7351d2f28894a14c0628ebbfbfd1 45 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 19 40 4.5E-9 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_11675 45cfb516cc82e367a6c9a9614077bd35 321 Gene3D G3DSA:1.10.3720.10 86 312 3.1E-20 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11675 45cfb516cc82e367a6c9a9614077bd35 321 SUPERFAMILY SSF161098 91 302 8.11E-18 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11675 45cfb516cc82e367a6c9a9614077bd35 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 319 1.1E-39 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 SUPERFAMILY SSF50104 1 99 3.61E-39 T 15-10-2018 IPR008991 Translation protein SH3-like domain superfamily C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 8.5E-31 T 15-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 Pfam PF00467 KOW motif 5 36 7.3E-9 T 15-10-2018 IPR005824 KOW C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.457 T 15-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 Gene3D G3DSA:2.30.30.30 1 100 8.5E-43 T 15-10-2018 IPR014722 Ribosomal protein L2, domain 2 C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 4.8E-42 T 15-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 SMART SM00739 2 29 8.2E-6 T 15-10-2018 IPR005824 KOW C2I28_08740 807c81e4637c452706dbb957108f6ec9 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 15-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 SUPERFAMILY SSF52540 263 482 2.51E-47 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 SMART SM00382 276 470 1.1E-6 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 SMART SM00382 27 224 5.8E-9 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 Gene3D G3DSA:3.40.50.300 253 490 6.9E-45 T 15-10-2018 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 Pfam PF00005 ABC transporter 268 421 2.1E-20 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 Pfam PF00005 ABC transporter 18 168 2.8E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 Gene3D G3DSA:3.40.50.300 1 236 1.5E-60 T 15-10-2018 C2I28_12810 57ac8d7b0512d4d3f780f0d72d96e1e0 493 SUPERFAMILY SSF52540 3 222 1.54E-58 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_00975 ddb8d158aeec302e7eda811dccf07df5 122 SUPERFAMILY SSF46785 9 118 5.03E-36 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00975 ddb8d158aeec302e7eda811dccf07df5 122 Gene3D G3DSA:1.10.10.10 4 121 1.8E-41 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00975 ddb8d158aeec302e7eda811dccf07df5 122 Pfam PF01638 HxlR-like helix-turn-helix 23 111 3.2E-36 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_11375 861f8403c07c826fbaa302baf5b004a4 1130 Pfam PF13555 P-loop containing region of AAA domain 13 62 5.6E-7 T 15-10-2018 C2I28_11375 861f8403c07c826fbaa302baf5b004a4 1130 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1002 1085 3.9E-15 T 15-10-2018 C2I28_11375 861f8403c07c826fbaa302baf5b004a4 1130 SUPERFAMILY SSF52540 4 1113 1.05E-28 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_11375 861f8403c07c826fbaa302baf5b004a4 1130 Gene3D G3DSA:3.40.50.300 1 225 7.5E-40 T 15-10-2018 C2I28_11375 861f8403c07c826fbaa302baf5b004a4 1130 Gene3D G3DSA:3.40.50.300 857 1117 4.4E-22 T 15-10-2018 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 4 389 7.7E-141 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 SUPERFAMILY SSF53901 269 390 8.85E-44 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 Gene3D G3DSA:3.40.47.10 4 274 8.0E-148 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 Gene3D G3DSA:3.40.47.10 124 388 8.0E-148 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 Pfam PF02803 Thiolase, C-terminal domain 269 390 4.1E-49 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 Pfam PF00108 Thiolase, N-terminal domain 3 261 1.9E-72 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 15-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 15-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 SUPERFAMILY SSF53901 2 268 3.84E-71 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_19915 3d0af722e93574f5da8d8d96b80e609d 393 PIRSF PIRSF000429 1 392 6.9E-127 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_20455 c74dfced316c6ab071627debb2e13bfb 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 46.745 T 15-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I28_20455 c74dfced316c6ab071627debb2e13bfb 253 Pfam PF03746 LamB/YcsF family 4 241 3.2E-104 T 15-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I28_20455 c74dfced316c6ab071627debb2e13bfb 253 Gene3D G3DSA:3.20.20.370 2 253 8.9E-105 T 15-10-2018 C2I28_20455 c74dfced316c6ab071627debb2e13bfb 253 SUPERFAMILY SSF88713 3 251 5.11E-100 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 SUPERFAMILY SSF52922 179 315 7.72E-33 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 Gene3D G3DSA:3.40.50.970 3 187 2.0E-58 T 15-10-2018 C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 SUPERFAMILY SSF52518 11 179 7.5E-52 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 Pfam PF02779 Transketolase, pyrimidine binding domain 12 176 2.0E-30 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 Gene3D G3DSA:3.40.50.920 188 315 9.1E-39 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 SMART SM00861 12 177 6.0E-47 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_16180 c06b9c4992ab2fdfc0cf0de1f3505258 315 Pfam PF02780 Transketolase, C-terminal domain 188 307 1.5E-28 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 SMART SM00382 358 559 3.3E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 Pfam PF00664 ABC transporter transmembrane region 19 288 2.2E-53 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 SUPERFAMILY SSF90123 5 317 1.44E-80 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 SUPERFAMILY SSF52540 326 569 1.66E-89 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 Gene3D G3DSA:3.40.50.300 324 575 2.3E-87 T 15-10-2018 C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 Pfam PF00005 ABC transporter 349 498 1.9E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_14725 b3643b070c1b41846bbe64c6ca9a744d 578 Gene3D G3DSA:1.20.1560.10 1 316 9.6E-89 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_02370 92e093ed532fdabfbfa237e2c75a81af 260 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 204 221 - T 15-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 C2I28_02370 92e093ed532fdabfbfa237e2c75a81af 260 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 258 7.3E-86 T 15-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 C2I28_02370 92e093ed532fdabfbfa237e2c75a81af 260 SUPERFAMILY SSF64005 28 253 5.1E-89 T 15-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 C2I28_02370 92e093ed532fdabfbfa237e2c75a81af 260 Pfam PF01255 Putative undecaprenyl diphosphate synthase 38 258 5.6E-84 T 15-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 C2I28_02370 92e093ed532fdabfbfa237e2c75a81af 260 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 259 40.36 T 15-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 C2I28_02370 92e093ed532fdabfbfa237e2c75a81af 260 Gene3D G3DSA:3.40.1180.10 16 260 9.0E-101 T 15-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 C2I28_03430 e1de3d11c91e98daff62684844b1d9c7 177 Pfam PF07670 Nucleoside recognition 46 146 2.5E-6 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_01590 f9ef2ea0d675e5f7dbd82af553610bee 122 SMART SM00345 15 74 9.2E-5 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01590 f9ef2ea0d675e5f7dbd82af553610bee 122 Gene3D G3DSA:1.10.10.10 8 121 4.5E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01590 f9ef2ea0d675e5f7dbd82af553610bee 122 SUPERFAMILY SSF46785 6 85 1.34E-15 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_01590 f9ef2ea0d675e5f7dbd82af553610bee 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 5.8E-8 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_27335 a80ae55c7002dc9263cd370d2770ad5e 134 Pfam PF13799 Domain of unknown function (DUF4183) 47 111 1.4E-18 T 15-10-2018 IPR025237 Domain of unknown function DUF4183 C2I28_23575 f6ea4380313238ea06942f488d89cda2 176 Gene3D G3DSA:3.40.630.30 3 174 9.3E-49 T 15-10-2018 C2I28_23575 f6ea4380313238ea06942f488d89cda2 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 1.0E-30 T 15-10-2018 IPR000182 GNAT domain C2I28_23575 f6ea4380313238ea06942f488d89cda2 176 SUPERFAMILY SSF55729 1 173 9.68E-51 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_04125 50f76e7def190d7ca27336535f5bf85f 425 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_04125 50f76e7def190d7ca27336535f5bf85f 425 SUPERFAMILY SSF103473 16 406 1.83E-30 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_04125 50f76e7def190d7ca27336535f5bf85f 425 Pfam PF07690 Major Facilitator Superfamily 20 335 9.3E-21 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_04125 50f76e7def190d7ca27336535f5bf85f 425 Gene3D G3DSA:1.20.1250.20 12 402 5.0E-22 T 15-10-2018 C2I28_26450 dfd92c78eaf05d628d47ca52aaabd803 221 SUPERFAMILY SSF52980 49 161 1.25E-24 T 15-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I28_26450 dfd92c78eaf05d628d47ca52aaabd803 221 Pfam PF04471 Restriction endonuclease 45 154 1.3E-30 T 15-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 C2I28_26450 dfd92c78eaf05d628d47ca52aaabd803 221 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 176 212 6.4E-13 T 15-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 C2I28_26450 dfd92c78eaf05d628d47ca52aaabd803 221 Gene3D G3DSA:3.40.1350.10 48 159 1.1E-13 T 15-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 C2I28_26450 dfd92c78eaf05d628d47ca52aaabd803 221 Gene3D G3DSA:3.30.65.10 164 218 2.1E-8 T 15-10-2018 C2I28_26450 dfd92c78eaf05d628d47ca52aaabd803 221 SUPERFAMILY SSF57783 171 212 3.23E-10 T 15-10-2018 C2I28_21700 894c4b531fd111e08b4128dfc4e9cecf 226 Pfam PF04239 Protein of unknown function (DUF421) 88 199 3.1E-34 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_21700 894c4b531fd111e08b4128dfc4e9cecf 226 Gene3D G3DSA:3.30.240.20 80 153 8.3E-25 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_21700 894c4b531fd111e08b4128dfc4e9cecf 226 Gene3D G3DSA:3.30.240.20 165 224 8.7E-18 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.0E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.0E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.0E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.0E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.0E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 186 0.0024 T 15-10-2018 C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 SUPERFAMILY SSF51735 2 212 3.84E-55 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 2.1E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 2.1E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 2.1E-9 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 Gene3D G3DSA:3.40.50.720 1 216 6.2E-58 T 15-10-2018 C2I28_10065 ed052edfb92e3add23fe6a85cdb8020a 217 Pfam PF00106 short chain dehydrogenase 2 186 3.8E-48 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Pfam PF01743 Poly A polymerase head domain 22 142 6.0E-39 T 15-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Gene3D G3DSA:3.30.460.10 3 144 5.6E-56 T 15-10-2018 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Gene3D G3DSA:1.10.246.80 339 397 2.9E-20 T 15-10-2018 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Gene3D G3DSA:1.20.58.560 241 338 2.2E-19 T 15-10-2018 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 SUPERFAMILY SSF81301 8 138 1.63E-44 T 15-10-2018 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Gene3D G3DSA:1.10.110.30 145 240 3.4E-30 T 15-10-2018 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 245 391 3.1E-34 T 15-10-2018 IPR032810 CCA-adding enzyme, C-terminal C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 170 228 3.6E-14 T 15-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 SUPERFAMILY SSF81891 140 394 4.05E-51 T 15-10-2018 C2I28_14985 a410d76268538b50d21bc1ae155c248b 397 Hamap MF_01263 CCA-adding enzyme [cca]. 2 395 39.692 T 15-10-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 C2I28_25755 78290cad34a2119fc6dd4d9633a264b1 334 Gene3D G3DSA:3.40.960.10 18 128 3.7E-10 T 15-10-2018 C2I28_18860 e44d521b055cec80b23971f83059c4ab 369 Pfam PF00534 Glycosyl transferases group 1 186 335 3.8E-26 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_18860 e44d521b055cec80b23971f83059c4ab 369 Gene3D G3DSA:3.40.50.2000 174 351 7.4E-51 T 15-10-2018 C2I28_18860 e44d521b055cec80b23971f83059c4ab 369 Gene3D G3DSA:3.40.50.2000 16 173 7.4E-51 T 15-10-2018 C2I28_18860 e44d521b055cec80b23971f83059c4ab 369 SUPERFAMILY SSF53756 5 366 7.33E-58 T 15-10-2018 C2I28_03055 2be61e017268a264a6f1d3552142019f 328 Gene3D G3DSA:2.30.42.10 118 196 3.1E-27 T 15-10-2018 C2I28_03055 2be61e017268a264a6f1d3552142019f 328 Pfam PF13180 PDZ domain 112 185 4.4E-17 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_03055 2be61e017268a264a6f1d3552142019f 328 SMART SM00228 109 176 2.3E-7 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_03055 2be61e017268a264a6f1d3552142019f 328 SUPERFAMILY SSF54211 206 323 5.31E-21 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_03055 2be61e017268a264a6f1d3552142019f 328 SUPERFAMILY SSF50156 117 204 7.76E-19 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_03055 2be61e017268a264a6f1d3552142019f 328 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 221 320 2.2E-9 T 15-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 C2I28_03055 2be61e017268a264a6f1d3552142019f 328 Gene3D G3DSA:3.30.230.10 197 327 3.3E-16 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 SMART SM01133 4 217 2.3E-102 T 15-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 Gene3D G3DSA:3.20.20.70 1 221 3.5E-96 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 Pfam PF01791 DeoC/LacD family aldolase 9 214 3.3E-19 T 15-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 3 219 38.499 T 15-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 7 214 3.4E-90 T 15-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 SUPERFAMILY SSF51569 4 218 5.86E-85 T 15-10-2018 C2I28_22095 23746fb4d8d21aa64765bb9f8f6101b3 224 PIRSF PIRSF001357 1 223 5.3E-80 T 15-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 Pfam PF00571 CBS domain 87 133 2.6E-7 T 15-10-2018 IPR000644 CBS domain C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 Pfam PF00571 CBS domain 147 204 6.9E-6 T 15-10-2018 IPR000644 CBS domain C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 SMART SM00116 153 204 0.0018 T 15-10-2018 IPR000644 CBS domain C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 SMART SM00116 86 134 1.7E-4 T 15-10-2018 IPR000644 CBS domain C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 Pfam PF08279 HTH domain 9 61 1.5E-12 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 Gene3D G3DSA:3.10.580.10 64 212 5.0E-59 T 15-10-2018 C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 Gene3D G3DSA:1.10.10.10 1 63 1.6E-8 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 SUPERFAMILY SSF54631 72 204 9.22E-24 T 15-10-2018 C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 PIRSF PIRSF026546 4 210 5.9E-102 T 15-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS C2I28_04280 338f82bc7a0ad4893592006b14f6ab02 212 SUPERFAMILY SSF46785 5 81 6.74E-14 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_10465 51167d02ed5d3ba68ea4090333245b78 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 264 4.1E-18 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_10465 51167d02ed5d3ba68ea4090333245b78 270 Gene3D G3DSA:1.10.3720.10 2 262 3.0E-62 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_10465 51167d02ed5d3ba68ea4090333245b78 270 SUPERFAMILY SSF161098 4 270 1.59E-66 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_25400 846cbe90ffb772832a504de02b6fdce7 551 SMART SM00631 65 275 5.9E-6 T 15-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 C2I28_25400 846cbe90ffb772832a504de02b6fdce7 551 Pfam PF00246 Zinc carboxypeptidase 72 190 2.8E-17 T 15-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 C2I28_25400 846cbe90ffb772832a504de02b6fdce7 551 Gene3D G3DSA:3.40.630.10 55 348 2.9E-33 T 15-10-2018 C2I28_25400 846cbe90ffb772832a504de02b6fdce7 551 SUPERFAMILY SSF53187 63 336 5.62E-39 T 15-10-2018 C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 SUPERFAMILY SSF46785 3 81 3.82E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 4.4E-17 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 3.7E-15 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.7E-15 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 3.7E-15 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 SMART SM00418 3 81 5.9E-29 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_13515 ae0ab75c5262bbc6f888d673118829bb 87 Gene3D G3DSA:1.10.10.10 1 86 4.7E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20860 352645ef0601d6c67a99ed0034ab2358 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 88 4.5E-8 T 15-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I28_20860 352645ef0601d6c67a99ed0034ab2358 96 Gene3D G3DSA:2.60.300.12 1 96 8.7E-7 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_20860 352645ef0601d6c67a99ed0034ab2358 96 SUPERFAMILY SSF89360 1 93 1.7E-14 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_20860 352645ef0601d6c67a99ed0034ab2358 96 PIRSF PIRSF034852 1 96 5.4E-40 T 15-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 C2I28_06655 ccf2867c3f4a91cc0aba472beb726319 194 Pfam PF04367 Protein of unknown function (DUF502) 56 157 5.3E-28 T 15-10-2018 IPR007462 Protein of unknown function DUF502 C2I28_15235 2d8a9a99d657ab358cd6da6646cf4a60 270 SUPERFAMILY SSF161098 5 270 2.35E-64 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15235 2d8a9a99d657ab358cd6da6646cf4a60 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 264 3.5E-23 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_15235 2d8a9a99d657ab358cd6da6646cf4a60 270 Gene3D G3DSA:1.10.3720.10 3 262 4.6E-54 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_11655 a30bea7b7dc8f6831279401d82fdd1c2 257 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 59 251 7.1E-56 T 15-10-2018 IPR018728 Domain of unknown function DUF2268 C2I28_21435 dd4f142478b44a9cbe42e653aaa07d72 305 Gene3D G3DSA:3.90.1200.10 115 243 2.9E-6 T 15-10-2018 C2I28_21435 dd4f142478b44a9cbe42e653aaa07d72 305 SUPERFAMILY SSF56112 26 283 3.5E-28 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_21435 dd4f142478b44a9cbe42e653aaa07d72 305 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 53 279 2.2E-36 T 15-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 C2I28_20430 a32930551d4ee2abf264e05e81140458 153 Gene3D G3DSA:2.40.50.100 72 150 2.1E-26 T 15-10-2018 C2I28_20430 a32930551d4ee2abf264e05e81140458 153 Pfam PF00364 Biotin-requiring enzyme 76 149 3.2E-21 T 15-10-2018 IPR000089 Biotin/lipoyl attachment C2I28_20430 a32930551d4ee2abf264e05e81140458 153 SUPERFAMILY SSF51230 76 150 1.83E-22 T 15-10-2018 IPR011053 Single hybrid motif C2I28_20430 a32930551d4ee2abf264e05e81140458 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 97 111 1.0E-12 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_20430 a32930551d4ee2abf264e05e81140458 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 80 93 1.0E-12 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_20430 a32930551d4ee2abf264e05e81140458 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 1.0E-12 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_20430 a32930551d4ee2abf264e05e81140458 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 151 9.9E-44 T 15-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 C2I28_11215 d18ddd4cda1fcbcc8bde503c20f6e8d7 258 SUPERFAMILY SSF52096 2 257 3.22E-80 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_11215 d18ddd4cda1fcbcc8bde503c20f6e8d7 258 Gene3D G3DSA:3.90.226.10 1 195 8.5E-69 T 15-10-2018 C2I28_11215 d18ddd4cda1fcbcc8bde503c20f6e8d7 258 Gene3D G3DSA:1.10.12.10 199 258 3.5E-24 T 15-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I28_11215 d18ddd4cda1fcbcc8bde503c20f6e8d7 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 15-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I28_11215 d18ddd4cda1fcbcc8bde503c20f6e8d7 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 257 1.2E-63 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_24520 362d8c40c97d3719dac5afa570896f94 476 Pfam PF00083 Sugar (and other) transporter 65 455 1.1E-36 T 15-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 C2I28_24520 362d8c40c97d3719dac5afa570896f94 476 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_24520 362d8c40c97d3719dac5afa570896f94 476 Gene3D G3DSA:1.20.1250.20 25 451 1.3E-68 T 15-10-2018 C2I28_24520 362d8c40c97d3719dac5afa570896f94 476 SUPERFAMILY SSF103473 20 459 1.31E-71 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_16515 a04b230de81a3a1076a8c21735cfc51b 165 SUPERFAMILY SSF109854 24 160 1.72E-15 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16515 a04b230de81a3a1076a8c21735cfc51b 165 Pfam PF12867 DinB superfamily 28 146 1.1E-7 T 15-10-2018 IPR024775 DinB-like domain C2I28_16515 a04b230de81a3a1076a8c21735cfc51b 165 Gene3D G3DSA:1.20.120.450 10 154 1.5E-10 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_02120 8ace22702bfd6c107571efd7eda88e21 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 8.8E-23 T 15-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I28_02120 8ace22702bfd6c107571efd7eda88e21 143 PIRSF PIRSF021287 1 123 7.2E-51 T 15-10-2018 IPR016783 Biofilm formation YmcA C2I28_02120 8ace22702bfd6c107571efd7eda88e21 143 SUPERFAMILY SSF158622 4 123 8.24E-35 T 15-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I28_02120 8ace22702bfd6c107571efd7eda88e21 143 Gene3D G3DSA:1.20.1500.10 1 124 5.1E-35 T 15-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I28_07255 1fe751347080a41e2d4952359a4b811e 140 Pfam PF01381 Helix-turn-helix 8 62 2.4E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_07255 1fe751347080a41e2d4952359a4b811e 140 Gene3D G3DSA:1.10.260.40 1 103 2.1E-19 T 15-10-2018 C2I28_07255 1fe751347080a41e2d4952359a4b811e 140 SMART SM00530 7 62 9.4E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_07255 1fe751347080a41e2d4952359a4b811e 140 SUPERFAMILY SSF47413 1 66 8.58E-17 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_15910 4306eeee31eb0ca13dbe74385e455f09 146 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 1 114 8.1E-46 T 15-10-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 C2I28_15910 4306eeee31eb0ca13dbe74385e455f09 146 SUPERFAMILY SSF53062 1 131 5.62E-34 T 15-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 C2I28_15910 4306eeee31eb0ca13dbe74385e455f09 146 Gene3D G3DSA:3.40.50.510 1 143 2.5E-36 T 15-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 C2I28_15910 4306eeee31eb0ca13dbe74385e455f09 146 Pfam PF03610 PTS system fructose IIA component 4 113 4.1E-29 T 15-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 C2I28_05665 211bf8877644e9f16df45c9058514983 371 Gene3D G3DSA:3.40.1830.10 3 165 1.8E-11 T 15-10-2018 IPR035097 Peptidase M29, N-terminal C2I28_05665 211bf8877644e9f16df45c9058514983 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 335 4.0E-59 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_05665 211bf8877644e9f16df45c9058514983 371 SUPERFAMILY SSF144052 1 360 1.23E-113 T 15-10-2018 C2I28_25620 f513a671f195c1b676240f02d5bbc11f 85 Gene3D G3DSA:2.30.30.90 4 84 8.1E-23 T 15-10-2018 IPR038157 Ferrous iron transporter, core domain C2I28_25620 f513a671f195c1b676240f02d5bbc11f 85 Pfam PF04023 FeoA domain 8 78 1.5E-18 T 15-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I28_25620 f513a671f195c1b676240f02d5bbc11f 85 SUPERFAMILY SSF50037 12 80 3.89E-18 T 15-10-2018 IPR008988 Transcriptional repressor, C-terminal C2I28_25620 f513a671f195c1b676240f02d5bbc11f 85 SMART SM00899 7 79 1.2E-19 T 15-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 SUPERFAMILY SSF55031 235 348 3.93E-25 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 PIRSF PIRSF001235 26 430 5.4E-127 T 15-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 Pfam PF01546 Peptidase family M20/M25/M40 100 426 2.2E-25 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 SUPERFAMILY SSF53187 30 429 1.26E-72 T 15-10-2018 C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 30 428 3.8E-129 T 15-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 Pfam PF07687 Peptidase dimerisation domain 235 333 2.0E-6 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 Gene3D G3DSA:3.40.630.10 43 421 3.6E-127 T 15-10-2018 C2I28_23170 0b6b612bfadc54bbf660ef14d7decfc2 430 Gene3D G3DSA:3.30.70.360 235 347 3.6E-127 T 15-10-2018 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 Gene3D G3DSA:1.20.1720.10 20 229 2.1E-45 T 15-10-2018 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 509 4.5E-159 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 8.1E-12 T 15-10-2018 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 8.1E-12 T 15-10-2018 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 8.1E-12 T 15-10-2018 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 8.1E-12 T 15-10-2018 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 Pfam PF07690 Major Facilitator Superfamily 24 415 5.3E-53 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_15605 be946bce658e0f90cd331cf71a2d6bb8 541 SUPERFAMILY SSF103473 13 521 8.11E-76 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_22515 1bf265e62369f8386302b16ae8294244 258 Pfam PF13346 ABC-2 family transporter protein 76 243 1.0E-5 T 15-10-2018 IPR025699 ABC-2 membrane transporter-like C2I28_18825 c7ad6788914a0760f016f4123ba1ca43 110 Pfam PF01381 Helix-turn-helix 7 62 3.2E-14 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_18825 c7ad6788914a0760f016f4123ba1ca43 110 SUPERFAMILY SSF47406 75 107 5.49E-11 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_18825 c7ad6788914a0760f016f4123ba1ca43 110 SUPERFAMILY SSF47413 1 68 4.02E-18 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_18825 c7ad6788914a0760f016f4123ba1ca43 110 SMART SM00530 6 62 6.2E-15 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_18825 c7ad6788914a0760f016f4123ba1ca43 110 Pfam PF08671 Anti-repressor SinI 75 102 3.0E-12 T 15-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I28_18825 c7ad6788914a0760f016f4123ba1ca43 110 Gene3D G3DSA:1.10.260.40 2 110 1.1E-30 T 15-10-2018 C2I28_08290 82efb1df7663d2982896e157546485e2 290 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 37.006 T 15-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 C2I28_08290 82efb1df7663d2982896e157546485e2 290 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 288 4.6E-85 T 15-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 C2I28_08290 82efb1df7663d2982896e157546485e2 290 SUPERFAMILY SSF53790 14 231 7.46E-83 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_08290 82efb1df7663d2982896e157546485e2 290 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 15-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 C2I28_08290 82efb1df7663d2982896e157546485e2 290 PIRSF PIRSF005917 3 290 1.5E-105 T 15-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 C2I28_08290 82efb1df7663d2982896e157546485e2 290 Gene3D G3DSA:3.40.1010.10 1 122 2.5E-48 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_08290 82efb1df7663d2982896e157546485e2 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 212 1.8E-27 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_08290 82efb1df7663d2982896e157546485e2 290 Gene3D G3DSA:3.30.950.10 123 238 3.3E-40 T 15-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 C2I28_22925 e9de6bc568894dbac04b0d95965fc2eb 212 Pfam PF03824 High-affinity nickel-transport protein 6 76 1.5E-6 T 15-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 C2I28_06740 6af37934b68e80250a58cfc24e0d1314 338 Pfam PF00899 ThiF family 5 240 1.9E-61 T 15-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I28_06740 6af37934b68e80250a58cfc24e0d1314 338 Gene3D G3DSA:3.40.50.720 1 250 6.9E-75 T 15-10-2018 C2I28_06740 6af37934b68e80250a58cfc24e0d1314 338 SUPERFAMILY SSF69572 3 329 3.92E-86 T 15-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I28_17450 1fd535c64a042b70575c9b9f1fd96921 496 Pfam PF08666 SAF domain 11 81 5.1E-12 T 15-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 C2I28_17450 1fd535c64a042b70575c9b9f1fd96921 496 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 108 495 3.6E-158 T 15-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 C2I28_17450 1fd535c64a042b70575c9b9f1fd96921 496 Gene3D G3DSA:3.90.1210.30 3 85 4.3E-30 T 15-10-2018 C2I28_17450 1fd535c64a042b70575c9b9f1fd96921 496 SMART SM00858 11 82 3.2E-12 T 15-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 C2I28_16590 6c0a1e78ba23401412cd9fe39d2fd3a7 105 Pfam PF11588 Protein of unknown function (DUF3243) 27 104 4.0E-30 T 15-10-2018 IPR021637 Protein of unknown function DUF3243 C2I28_16590 6c0a1e78ba23401412cd9fe39d2fd3a7 105 Gene3D G3DSA:1.10.760.20 22 105 1.7E-33 T 15-10-2018 IPR038292 YmfJ/YflH superfamily C2I28_10945 dfe12400161bac522c92a0a4a20c1130 72 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 29 38 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_10945 dfe12400161bac522c92a0a4a20c1130 72 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 47 61 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_10945 dfe12400161bac522c92a0a4a20c1130 72 Gene3D G3DSA:1.10.8.910 14 72 4.5E-30 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_10945 dfe12400161bac522c92a0a4a20c1130 72 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 14 68 6.0E-21 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 Gene3D G3DSA:3.50.50.60 7 363 6.5E-108 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 Gene3D G3DSA:3.30.9.50 74 301 6.5E-108 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 Gene3D G3DSA:3.40.30.120 396 540 5.9E-45 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 Pfam PF01494 FAD binding domain 6 365 3.6E-93 T 15-10-2018 IPR002938 FAD-binding domain GO:0071949 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 2.4E-37 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.4E-37 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 2.4E-37 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 2.4E-37 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 355 2.4E-37 T 15-10-2018 C2I28_20515 92bd35ca9207322474b4bef59b8b811a 540 SUPERFAMILY SSF51905 6 371 4.75E-52 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 Gene3D G3DSA:3.40.250.10 156 280 3.7E-35 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 SUPERFAMILY SSF52821 157 278 3.54E-33 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 SMART SM00450 157 274 2.4E-20 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 SMART SM00450 7 133 1.5E-15 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 Pfam PF00581 Rhodanese-like domain 160 269 6.4E-17 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 Pfam PF00581 Rhodanese-like domain 7 129 2.0E-16 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 Gene3D G3DSA:3.40.250.10 1 152 1.3E-45 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_17670 95c41c5013a7765b3bf3323c3c579cc7 280 SUPERFAMILY SSF52821 3 153 1.96E-37 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_06195 222ac430035699652fc3ec5e7a82c4b3 199 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 9.4E-89 T 15-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I28_06195 222ac430035699652fc3ec5e7a82c4b3 199 Gene3D G3DSA:3.40.50.300 3 199 2.0E-85 T 15-10-2018 C2I28_06195 222ac430035699652fc3ec5e7a82c4b3 199 SUPERFAMILY SSF52540 25 195 3.29E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06195 222ac430035699652fc3ec5e7a82c4b3 199 Pfam PF01583 Adenylylsulphate kinase 27 181 3.1E-74 T 15-10-2018 C2I28_06195 222ac430035699652fc3ec5e7a82c4b3 199 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 39.556 T 15-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 C2I28_23535 3854fbbdca3cba312dc8e92989082e86 139 Gene3D G3DSA:1.10.10.10 1 139 8.1E-46 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23535 3854fbbdca3cba312dc8e92989082e86 139 SUPERFAMILY SSF46785 2 135 6.97E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23535 3854fbbdca3cba312dc8e92989082e86 139 Pfam PF02082 Transcriptional regulator 2 80 2.0E-20 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 SUPERFAMILY SSF52172 1 129 4.84E-30 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 Gene3D G3DSA:3.40.50.12740 2 198 6.4E-61 T 15-10-2018 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 SMART SM00421 136 193 3.6E-22 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 Pfam PF00072 Response regulator receiver domain 4 113 1.6E-25 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 SMART SM00448 2 113 9.8E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 1.3E-12 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 1.3E-12 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 1.3E-12 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 191 2.0E-19 T 15-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 C2I28_15500 17f50d65f23c3120f6f83be223bb1687 200 SUPERFAMILY SSF46894 126 199 5.78E-20 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_07705 9e03b58d419fe01e4d9041b2c378088a 458 Pfam PF13425 O-antigen ligase like membrane protein 11 450 3.3E-105 T 15-10-2018 C2I28_03030 faed887d64bbee1d24b5b2d071109271 200 SUPERFAMILY SSF46689 6 62 5.92E-5 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_03030 faed887d64bbee1d24b5b2d071109271 200 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 180 4.8E-58 T 15-10-2018 IPR014243 Transcription factor, RsfA C2I28_03030 faed887d64bbee1d24b5b2d071109271 200 Pfam PF13921 Myb-like DNA-binding domain 9 62 3.7E-5 T 15-10-2018 C2I28_12780 4eec9b46786e3ec931e00f259cad5d8f 176 Pfam PF03358 NADPH-dependent FMN reductase 45 104 3.2E-9 T 15-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I28_12780 4eec9b46786e3ec931e00f259cad5d8f 176 SUPERFAMILY SSF52218 1 172 1.3E-41 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_12780 4eec9b46786e3ec931e00f259cad5d8f 176 Gene3D G3DSA:3.40.50.360 1 176 1.2E-46 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_12780 4eec9b46786e3ec931e00f259cad5d8f 176 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 15-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 C2I28_01560 80790e6cc693f85046b9c0507f729cee 365 Pfam PF03845 Spore germination protein 10 331 1.7E-80 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_01560 80790e6cc693f85046b9c0507f729cee 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 11 361 5.0E-78 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 15-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 SUPERFAMILY SSF69864 170 397 6.02E-93 T 15-10-2018 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 396 54.27 T 15-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 Gene3D G3DSA:3.90.1260.10 173 401 3.9E-92 T 15-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 15-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 SUPERFAMILY SSF52402 1 170 4.19E-47 T 15-10-2018 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 Gene3D G3DSA:3.40.50.620 5 172 1.5E-65 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 Pfam PF00764 Arginosuccinate synthase 7 390 8.4E-179 T 15-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05500 3d4b67921049f2910cc7ec822f2136e5 402 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 393 3.2E-173 T 15-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_09975 bac65bcf09a242aa1fdf752a4e6b87cb 162 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 1 161 7.0E-83 T 15-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 C2I28_09975 bac65bcf09a242aa1fdf752a4e6b87cb 162 SUPERFAMILY SSF50814 2 161 9.02E-76 T 15-10-2018 IPR012674 Calycin C2I28_09975 bac65bcf09a242aa1fdf752a4e6b87cb 162 Pfam PF05870 Phenolic acid decarboxylase (PAD) 1 158 7.3E-82 T 15-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 C2I28_09975 bac65bcf09a242aa1fdf752a4e6b87cb 162 Gene3D G3DSA:2.40.128.20 1 161 1.4E-82 T 15-10-2018 IPR012674 Calycin C2I28_09975 bac65bcf09a242aa1fdf752a4e6b87cb 162 PIRSF PIRSF011561 1 162 1.8E-95 T 15-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 C2I28_20470 0b61475403984461d8e057a89a8e09df 208 Pfam PF01965 DJ-1/PfpI family 4 176 6.8E-36 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_20470 0b61475403984461d8e057a89a8e09df 208 SUPERFAMILY SSF52317 4 178 3.53E-33 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_20470 0b61475403984461d8e057a89a8e09df 208 Gene3D G3DSA:3.40.50.880 1 208 6.9E-54 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_25815 e003d04c3d392d7b62a370a86975c081 144 SMART SM00860 23 130 4.3E-9 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_25815 e003d04c3d392d7b62a370a86975c081 144 Gene3D G3DSA:3.40.1580.10 3 143 4.5E-30 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_25815 e003d04c3d392d7b62a370a86975c081 144 Pfam PF14567 SMI1-KNR4 cell-wall 8 132 3.8E-27 T 15-10-2018 C2I28_25815 e003d04c3d392d7b62a370a86975c081 144 SUPERFAMILY SSF160631 5 142 1.57E-28 T 15-10-2018 C2I28_09190 1e0a914036cc58dfb9781ecf1ee992d5 201 SMART SM00331 9 198 1.9E-36 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09190 1e0a914036cc58dfb9781ecf1ee992d5 201 SUPERFAMILY SSF81606 11 195 2.09E-16 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09190 1e0a914036cc58dfb9781ecf1ee992d5 201 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 35 192 1.3E-11 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_09190 1e0a914036cc58dfb9781ecf1ee992d5 201 Gene3D G3DSA:3.60.40.10 3 198 2.3E-44 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_07155 a8559f3635ee05c3b91d42311fcf194f 176 SUPERFAMILY SSF53271 6 175 5.11E-24 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_07155 a8559f3635ee05c3b91d42311fcf194f 176 Gene3D G3DSA:3.40.50.2020 23 176 6.1E-18 T 15-10-2018 C2I28_07155 a8559f3635ee05c3b91d42311fcf194f 176 Pfam PF00156 Phosphoribosyl transferase domain 89 174 4.7E-8 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_03495 395c0457f162786837a30ccc5705f426 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 1.2E-54 T 15-10-2018 IPR014204 Sporulation stage V, protein AE C2I28_03495 395c0457f162786837a30ccc5705f426 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 2 111 2.6E-41 T 15-10-2018 IPR005562 SpoVA C2I28_21140 927fd52205d6b1267a1c902d86c02142 530 PIRSF PIRSF006060 1 461 2.5E-81 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_21140 927fd52205d6b1267a1c902d86c02142 530 PIRSF PIRSF006060 448 529 9.2 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_21140 927fd52205d6b1267a1c902d86c02142 530 Pfam PF13520 Amino acid permease 11 470 2.7E-46 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_21140 927fd52205d6b1267a1c902d86c02142 530 Gene3D G3DSA:1.20.1740.10 7 462 1.6E-76 T 15-10-2018 C2I28_18390 a8535e177984d85d91cf86ee5a9cca7a 134 Pfam PF04138 GtrA-like protein 10 124 4.5E-29 T 15-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 8 71 2.9E-21 T 15-10-2018 IPR019457 Uncharacterised domain YojJ, N-terminal C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 PIRSF PIRSF004793 12 208 6.1E-58 T 15-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 Hamap MF_00838 Diadenylate cyclase [dacB]. 16 203 34.32 T 15-10-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 81 197 1.3E-40 T 15-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 Gene3D G3DSA:1.10.287.770 2 71 4.2E-17 T 15-10-2018 C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 SUPERFAMILY SSF143597 36 201 3.92E-50 T 15-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I28_06215 2c215bd85d455e350c2aca8f3b7f1dde 208 Gene3D G3DSA:3.40.1700.10 74 203 1.2E-49 T 15-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily C2I28_06220 a00125b68983cd14acfa789f0780904b 127 Gene3D G3DSA:3.10.180.10 2 127 4.7E-28 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_06220 a00125b68983cd14acfa789f0780904b 127 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 111 2.4E-14 T 15-10-2018 C2I28_06220 a00125b68983cd14acfa789f0780904b 127 SUPERFAMILY SSF54593 1 125 2.15E-27 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_03380 0d66d835383bfe591807d51444ef7ee3 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.2E-8 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_03380 0d66d835383bfe591807d51444ef7ee3 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 2.2E-8 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_03380 0d66d835383bfe591807d51444ef7ee3 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.2E-8 T 15-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 C2I28_03380 0d66d835383bfe591807d51444ef7ee3 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 2.2E-22 T 15-10-2018 C2I28_03380 0d66d835383bfe591807d51444ef7ee3 82 Gene3D G3DSA:3.30.70.20 2 82 4.0E-35 T 15-10-2018 C2I28_03380 0d66d835383bfe591807d51444ef7ee3 82 SUPERFAMILY SSF54862 3 72 4.66E-15 T 15-10-2018 C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 SUPERFAMILY SSF48498 79 184 1.78E-15 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 53 4.6E-12 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 SUPERFAMILY SSF46689 2 82 8.21E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 Gene3D G3DSA:1.10.357.10 1 192 1.4E-40 T 15-10-2018 C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 83 179 6.9E-12 T 15-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.2E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_20505 82cd8202a38c55394a358c61715b28f9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.2E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_15895 24a4b1ad843cf32b33002a74f2652f4b 486 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 12 457 3.5E-124 T 15-10-2018 IPR003846 Uncharacterised protein family UPF0061 C2I28_15895 24a4b1ad843cf32b33002a74f2652f4b 486 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 472 44.835 T 15-10-2018 IPR003846 Uncharacterised protein family UPF0061 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 408 576 4.8E-46 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 PIRSF PIRSF037846 11 170 5.7E-29 T 15-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 PIRSF PIRSF037846 317 580 4.1E-79 T 15-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 PIRSF PIRSF037846 168 334 1.8E-26 T 15-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SMART SM00646 466 576 9.7E-34 T 15-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Gene3D G3DSA:2.30.30.40 174 243 2.3E-21 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Gene3D G3DSA:2.30.30.40 98 166 2.1E-21 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Gene3D G3DSA:3.40.630.40 403 580 3.2E-56 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Gene3D G3DSA:2.30.30.40 251 320 4.8E-21 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Gene3D G3DSA:2.30.30.40 31 97 7.0E-19 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SMART SM00287 327 388 2.5E-9 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SMART SM00287 103 165 1.2E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SMART SM00287 180 242 1.2E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SMART SM00287 30 91 2.4E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SMART SM00287 257 319 6.0E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 SUPERFAMILY SSF53187 406 579 1.73E-49 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Gene3D G3DSA:2.30.30.40 329 385 8.2E-11 T 15-10-2018 C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Pfam PF08239 Bacterial SH3 domain 265 316 2.6E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Pfam PF08239 Bacterial SH3 domain 188 239 3.5E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Pfam PF08239 Bacterial SH3 domain 39 88 1.4E-16 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Pfam PF08239 Bacterial SH3 domain 336 384 1.5E-11 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_23325 0c3a18053cd715cf3574c61e3d9bbc6b 583 Pfam PF08239 Bacterial SH3 domain 111 162 3.5E-15 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_07065 4c5045512abfba1584ce867a2db7cd8e 134 Gene3D G3DSA:3.40.630.30 1 132 4.6E-25 T 15-10-2018 C2I28_07065 4c5045512abfba1584ce867a2db7cd8e 134 Pfam PF13673 Acetyltransferase (GNAT) domain 32 132 4.3E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_07065 4c5045512abfba1584ce867a2db7cd8e 134 SUPERFAMILY SSF55729 25 132 3.09E-16 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_25255 e9ad2ac885cefafb3296a3e5ab2912da 237 Pfam PF14342 Domain of unknown function (DUF4396) 94 234 3.0E-41 T 15-10-2018 IPR025509 Domain of unknown function DUF4396 C2I28_12700 23842e4d512062444e1c4c97098bd145 594 Gene3D G3DSA:3.40.50.300 352 593 4.2E-89 T 15-10-2018 C2I28_12700 23842e4d512062444e1c4c97098bd145 594 SUPERFAMILY SSF90123 20 339 1.7E-85 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_12700 23842e4d512062444e1c4c97098bd145 594 Gene3D G3DSA:1.20.1560.10 9 342 2.9E-104 T 15-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 C2I28_12700 23842e4d512062444e1c4c97098bd145 594 SUPERFAMILY SSF52540 345 592 2.42E-91 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12700 23842e4d512062444e1c4c97098bd145 594 SMART SM00382 381 582 1.1E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12700 23842e4d512062444e1c4c97098bd145 594 Pfam PF00664 ABC transporter transmembrane region 40 309 7.4E-55 T 15-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 C2I28_12700 23842e4d512062444e1c4c97098bd145 594 Pfam PF00005 ABC transporter 372 521 1.0E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_10070 6eed86f84ddfcec86abeeef56966b469 104 Pfam PF08838 Protein of unknown function (DUF1811) 4 103 8.1E-47 T 15-10-2018 IPR014938 Protein of unknown function DUF1811 C2I28_10070 6eed86f84ddfcec86abeeef56966b469 104 Gene3D G3DSA:2.30.30.340 52 104 2.0E-26 T 15-10-2018 C2I28_10070 6eed86f84ddfcec86abeeef56966b469 104 SUPERFAMILY SSF101697 2 104 7.72E-46 T 15-10-2018 IPR036289 Hypothetical protein YfhH C2I28_10070 6eed86f84ddfcec86abeeef56966b469 104 Gene3D G3DSA:1.10.287.880 1 51 8.9E-27 T 15-10-2018 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 Gene3D G3DSA:3.40.50.280 551 714 1.0E-54 T 15-10-2018 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 Pfam PF02310 B12 binding domain 587 697 9.6E-17 T 15-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 SUPERFAMILY SSF52242 552 713 3.14E-58 T 15-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 584 714 2.3E-61 T 15-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 Pfam PF01642 Methylmalonyl-CoA mutase 32 545 4.6E-236 T 15-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 SUPERFAMILY SSF51703 29 547 2.94E-216 T 15-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 Gene3D G3DSA:3.20.20.240 31 547 1.8E-238 T 15-10-2018 C2I28_03740 b3dcbd3fe463bbe06980235f7ba7a857 716 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 31 551 4.5E-271 T 15-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 C2I28_23680 f48ff51201812c400e3bf8818b2984c1 240 SUPERFAMILY SSF52266 47 238 4.89E-45 T 15-10-2018 C2I28_23680 f48ff51201812c400e3bf8818b2984c1 240 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 72 228 2.6E-25 T 15-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I28_23680 f48ff51201812c400e3bf8818b2984c1 240 Gene3D G3DSA:3.40.50.1110 39 238 1.7E-47 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_02630 f690f47474656a719966e5912854604b 76 SUPERFAMILY SSF54814 15 61 1.31E-8 T 15-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 C2I28_02630 f690f47474656a719966e5912854604b 76 Gene3D G3DSA:3.30.300.20 1 75 1.1E-7 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_02630 f690f47474656a719966e5912854604b 76 Hamap MF_00088 UPF0109 protein . 1 75 21.699 T 15-10-2018 IPR020627 Uncharacterised protein family UPF0109 C2I28_02630 f690f47474656a719966e5912854604b 76 Pfam PF13083 KH domain 3 74 1.9E-26 T 15-10-2018 C2I28_03855 94a4f5c5d8be61168e6a52e845ccfffb 130 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 129 24.566 T 15-10-2018 IPR011605 NusB antitermination factor GO:0006353 C2I28_03855 94a4f5c5d8be61168e6a52e845ccfffb 130 SUPERFAMILY SSF48013 3 124 8.24E-40 T 15-10-2018 IPR035926 NusB-like superfamily C2I28_03855 94a4f5c5d8be61168e6a52e845ccfffb 130 Pfam PF01029 NusB family 4 125 6.1E-38 T 15-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 C2I28_03855 94a4f5c5d8be61168e6a52e845ccfffb 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 126 2.2E-43 T 15-10-2018 IPR011605 NusB antitermination factor GO:0006353 C2I28_03855 94a4f5c5d8be61168e6a52e845ccfffb 130 Gene3D G3DSA:1.10.940.10 1 130 2.5E-46 T 15-10-2018 IPR035926 NusB-like superfamily C2I28_12870 fcc7320ead5ec8180081a1856b46b42c 469 Pfam PF13641 Glycosyltransferase like family 2 63 327 5.0E-18 T 15-10-2018 C2I28_12870 fcc7320ead5ec8180081a1856b46b42c 469 SUPERFAMILY SSF53448 60 372 2.33E-43 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_12870 fcc7320ead5ec8180081a1856b46b42c 469 Gene3D G3DSA:3.90.550.10 55 317 6.0E-38 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_11700 9761a193251f1760ccdb7353a5b7af20 548 Gene3D G3DSA:3.40.190.10 57 534 5.2E-173 T 15-10-2018 C2I28_11700 9761a193251f1760ccdb7353a5b7af20 548 PIRSF PIRSF002741 1 547 3.4E-140 T 15-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 C2I28_11700 9761a193251f1760ccdb7353a5b7af20 548 Gene3D G3DSA:3.90.76.10 77 199 5.2E-173 T 15-10-2018 C2I28_11700 9761a193251f1760ccdb7353a5b7af20 548 Gene3D G3DSA:3.10.105.10 305 521 5.2E-173 T 15-10-2018 C2I28_11700 9761a193251f1760ccdb7353a5b7af20 548 SUPERFAMILY SSF53850 40 540 5.29E-138 T 15-10-2018 C2I28_11700 9761a193251f1760ccdb7353a5b7af20 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 470 3.7E-87 T 15-10-2018 IPR000914 Solute-binding protein family 5 domain C2I28_17830 1022141e4d786486476dfac8b0aa5366 308 TIGRFAM TIGR00688 rarD: protein RarD 8 265 2.0E-82 T 15-10-2018 IPR004626 RarD protein GO:0005887 C2I28_17830 1022141e4d786486476dfac8b0aa5366 308 SUPERFAMILY SSF103481 42 149 3.27E-10 T 15-10-2018 C2I28_17830 1022141e4d786486476dfac8b0aa5366 308 Pfam PF00892 EamA-like transporter family 9 148 9.4E-11 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_17830 1022141e4d786486476dfac8b0aa5366 308 Pfam PF00892 EamA-like transporter family 159 288 1.3E-6 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_17830 1022141e4d786486476dfac8b0aa5366 308 SUPERFAMILY SSF103481 197 291 5.1E-10 T 15-10-2018 C2I28_13745 13f79e850fd5c0f6096fe4037445f827 417 SUPERFAMILY SSF53756 4 397 1.38E-45 T 15-10-2018 C2I28_13745 13f79e850fd5c0f6096fe4037445f827 417 Pfam PF13439 Glycosyltransferase Family 4 17 204 2.8E-12 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_13745 13f79e850fd5c0f6096fe4037445f827 417 Gene3D G3DSA:3.40.50.2000 3 217 1.6E-19 T 15-10-2018 C2I28_13745 13f79e850fd5c0f6096fe4037445f827 417 Gene3D G3DSA:3.40.50.2000 218 389 3.9E-19 T 15-10-2018 C2I28_13745 13f79e850fd5c0f6096fe4037445f827 417 Pfam PF00534 Glycosyl transferases group 1 209 376 1.2E-10 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_13335 86100697f51114a7cc952bb692797f59 533 SUPERFAMILY SSF53474 28 195 4.1E-5 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_20820 79d7500b8c7cdb8365a3813a23f20358 102 SUPERFAMILY SSF51182 41 100 2.09E-13 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_20820 79d7500b8c7cdb8365a3813a23f20358 102 Pfam PF07883 Cupin domain 41 86 2.6E-8 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_20820 79d7500b8c7cdb8365a3813a23f20358 102 Gene3D G3DSA:2.60.120.10 37 101 1.3E-13 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 Gene3D G3DSA:1.10.10.10 2 75 1.6E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 SUPERFAMILY SSF46785 6 81 9.79E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 Pfam PF00155 Aminotransferase class I and II 116 466 1.1E-35 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-7 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-7 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 SMART SM00345 15 74 5.3E-15 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 Gene3D G3DSA:3.90.1150.10 114 473 3.6E-106 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 Gene3D G3DSA:3.40.640.10 150 369 3.6E-106 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 SUPERFAMILY SSF53383 109 475 3.38E-92 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_20170 d5da1704decbc9bdcca62586eed3caed 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 4.7E-16 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_11535 9b42f4043e4ee1a76e9fd64d7fd6ec39 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 79 1.2E-21 T 15-10-2018 IPR002744 MIP18 family-like C2I28_11535 9b42f4043e4ee1a76e9fd64d7fd6ec39 102 Gene3D G3DSA:3.30.300.130 1 102 3.2E-37 T 15-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I28_11535 9b42f4043e4ee1a76e9fd64d7fd6ec39 102 SUPERFAMILY SSF117916 2 100 1.28E-32 T 15-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I28_08780 00ae199d26950e9f9d76cdbbdb2ed567 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 6.5E-56 T 15-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08780 00ae199d26950e9f9d76cdbbdb2ed567 146 SUPERFAMILY SSF52080 4 144 4.19E-50 T 15-10-2018 IPR036227 Ribosomal L18e/L15P superfamily C2I28_08780 00ae199d26950e9f9d76cdbbdb2ed567 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 6.9E-39 T 15-10-2018 IPR021131 Ribosomal protein L18e/L15P C2I28_08780 00ae199d26950e9f9d76cdbbdb2ed567 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 15-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08780 00ae199d26950e9f9d76cdbbdb2ed567 146 Gene3D G3DSA:3.100.10.10 66 146 1.2E-28 T 15-10-2018 C2I28_08780 00ae199d26950e9f9d76cdbbdb2ed567 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 23.138 T 15-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 C2I28_07300 e9724793b72128afd8bb256e8576373b 246 Gene3D G3DSA:3.30.360.40 171 246 1.1E-30 T 15-10-2018 C2I28_07300 e9724793b72128afd8bb256e8576373b 246 Pfam PF08680 TATA-box binding 52 246 3.4E-47 T 15-10-2018 IPR014794 TATA-box binding C2I28_07300 e9724793b72128afd8bb256e8576373b 246 Gene3D G3DSA:3.30.2030.10 31 170 9.3E-35 T 15-10-2018 C2I28_07300 e9724793b72128afd8bb256e8576373b 246 SUPERFAMILY SSF143842 35 243 7.32E-47 T 15-10-2018 IPR036209 YwmB-like superfamily C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 SUPERFAMILY SSF103190 113 202 1.02E-10 T 15-10-2018 IPR029151 Periplasmic sensor-like domain superfamily C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 Pfam PF02743 Cache domain 34 274 3.5E-35 T 15-10-2018 IPR033479 Double Cache domain 1 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 SUPERFAMILY SSF58104 334 670 4.58E-67 T 15-10-2018 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 Pfam PF00672 HAMP domain 314 360 9.8E-11 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 Gene3D G3DSA:1.10.287.950 371 670 3.7E-61 T 15-10-2018 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 460 623 1.2E-38 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 Gene3D G3DSA:3.30.450.20 43 192 1.7E-20 T 15-10-2018 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 SMART SM00283 395 670 1.9E-65 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 Gene3D G3DSA:1.20.1480.50 277 370 1.4E-16 T 15-10-2018 C2I28_10765 9f0f76d742e52aa228b374d41a983107 672 SMART SM00304 314 366 4.5E-13 T 15-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 C2I28_17435 0fc312163ab2c83b966d95deb477b9ce 460 Pfam PF13347 MFS/sugar transport protein 26 446 6.9E-95 T 15-10-2018 C2I28_17435 0fc312163ab2c83b966d95deb477b9ce 460 Gene3D G3DSA:1.20.1250.20 25 442 5.0E-25 T 15-10-2018 C2I28_17435 0fc312163ab2c83b966d95deb477b9ce 460 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 459 2.5E-149 T 15-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 C2I28_17435 0fc312163ab2c83b966d95deb477b9ce 460 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 75 102 - T 15-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 C2I28_17435 0fc312163ab2c83b966d95deb477b9ce 460 SUPERFAMILY SSF103473 24 451 1.92E-40 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_00355 c362e961981e7b1f723070e862e2fa02 248 Pfam PF03988 Repeat of Unknown Function (DUF347) 185 236 1.5E-13 T 15-10-2018 IPR007136 Protein of unknown function DUF347 C2I28_00355 c362e961981e7b1f723070e862e2fa02 248 Pfam PF03988 Repeat of Unknown Function (DUF347) 130 181 4.4E-16 T 15-10-2018 IPR007136 Protein of unknown function DUF347 C2I28_00355 c362e961981e7b1f723070e862e2fa02 248 Pfam PF03988 Repeat of Unknown Function (DUF347) 65 116 1.1E-16 T 15-10-2018 IPR007136 Protein of unknown function DUF347 C2I28_00355 c362e961981e7b1f723070e862e2fa02 248 Pfam PF03988 Repeat of Unknown Function (DUF347) 10 61 9.0E-19 T 15-10-2018 IPR007136 Protein of unknown function DUF347 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 ProSitePatterns PS01228 Hypothetical cof family signature 1. 11 22 - T 15-10-2018 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 Gene3D G3DSA:3.40.50.1000 10 88 4.9E-32 T 15-10-2018 IPR023214 HAD superfamily C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 Gene3D G3DSA:3.40.50.1000 173 243 2.8E-33 T 15-10-2018 IPR023214 HAD superfamily C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 SUPERFAMILY SSF56784 6 248 8.14E-69 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 Gene3D G3DSA:3.30.1240.10 89 130 4.9E-32 T 15-10-2018 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 11 216 1.6E-29 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 12 244 1.4E-32 T 15-10-2018 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 Gene3D G3DSA:3.30.1240.10 144 172 2.8E-33 T 15-10-2018 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 ProSitePatterns PS01229 Hypothetical cof family signature 2. 197 219 - T 15-10-2018 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 Pfam PF08282 haloacid dehalogenase-like hydrolase 141 243 8.8E-31 T 15-10-2018 C2I28_17675 e9a6f37edd6949a7bd791f9cee7c7c07 249 Pfam PF08282 haloacid dehalogenase-like hydrolase 12 130 6.3E-30 T 15-10-2018 C2I28_24310 8ab6cc973f0ce6384f4e24ad40d14573 293 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 291 5.8E-64 T 15-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I28_24310 8ab6cc973f0ce6384f4e24ad40d14573 293 SUPERFAMILY SSF54506 3 293 1.4E-68 T 15-10-2018 C2I28_24310 8ab6cc973f0ce6384f4e24ad40d14573 293 Pfam PF02567 Phenazine biosynthesis-like protein 9 283 1.3E-61 T 15-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I28_24310 8ab6cc973f0ce6384f4e24ad40d14573 293 Gene3D G3DSA:3.10.310.10 8 123 7.1E-86 T 15-10-2018 C2I28_24310 8ab6cc973f0ce6384f4e24ad40d14573 293 PIRSF PIRSF016184 1 293 2.3E-89 T 15-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 C2I28_24310 8ab6cc973f0ce6384f4e24ad40d14573 293 Gene3D G3DSA:3.10.310.10 124 282 7.1E-86 T 15-10-2018 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 SUPERFAMILY SSF63520 286 386 1.02E-16 T 15-10-2018 IPR036634 PRD domain superfamily GO:0006355 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 Gene3D G3DSA:1.10.1790.10 287 386 1.1E-9 T 15-10-2018 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 397 449 6.4E-5 T 15-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 SUPERFAMILY SSF52794 394 468 4.97E-9 T 15-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 533 675 8.9E-31 T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_00085 d2bcd11758235900e6adaa92367de236 680 Pfam PF00874 PRD domain 296 384 3.1E-15 T 15-10-2018 IPR011608 PRD domain GO:0006355 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 Gene3D G3DSA:3.40.50.2300 396 480 2.6E-9 T 15-10-2018 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 Gene3D G3DSA:3.40.930.10 529 680 1.8E-48 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 SUPERFAMILY SSF55804 529 675 2.62E-36 T 15-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 C2I28_00085 d2bcd11758235900e6adaa92367de236 680 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 580 596 - T 15-10-2018 IPR002178 PTS EIIA type-2 domain C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 SUPERFAMILY SSF54001 301 415 2.7E-28 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 Gene3D G3DSA:3.90.1720.10 28 162 3.7E-33 T 15-10-2018 C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 Gene3D G3DSA:3.90.1720.10 291 416 1.9E-31 T 15-10-2018 C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 Gene3D G3DSA:3.90.1720.10 164 290 1.0E-44 T 15-10-2018 C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 Pfam PF00877 NlpC/P60 family 181 288 1.4E-29 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 Pfam PF00877 NlpC/P60 family 50 158 2.5E-19 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 Pfam PF00877 NlpC/P60 family 311 413 4.1E-18 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 SUPERFAMILY SSF54001 39 162 7.52E-29 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_00670 eb8e2cb4fb965605222eff7d244ec3bf 416 SUPERFAMILY SSF54001 170 289 8.17E-40 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_18040 81576b2270bb389b4d351b555b6991fd 231 SUPERFAMILY SSF160104 11 160 1.7E-18 T 15-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 C2I28_18040 81576b2270bb389b4d351b555b6991fd 231 Pfam PF09844 Uncharacterized conserved protein (COG2071) 8 221 4.2E-71 T 15-10-2018 IPR018644 Protein of unknown function DUF2071 C2I28_18040 81576b2270bb389b4d351b555b6991fd 231 Gene3D G3DSA:2.40.400.10 7 162 1.8E-8 T 15-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 C2I28_00510 2ec307d5e1d5fd400d3cc33f3cdc4c0d 213 SMART SM00530 13 68 8.6E-10 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_00510 2ec307d5e1d5fd400d3cc33f3cdc4c0d 213 Pfam PF01381 Helix-turn-helix 14 67 6.4E-10 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_00510 2ec307d5e1d5fd400d3cc33f3cdc4c0d 213 SUPERFAMILY SSF47413 8 72 1.6E-11 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_00510 2ec307d5e1d5fd400d3cc33f3cdc4c0d 213 Gene3D G3DSA:1.10.260.40 1 83 6.2E-12 T 15-10-2018 C2I28_00510 2ec307d5e1d5fd400d3cc33f3cdc4c0d 213 Pfam PF06803 Protein of unknown function (DUF1232) 173 204 1.6E-12 T 15-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I28_07590 72f3852b7f9ba79de211f8ca5f578ce5 247 SUPERFAMILY SSF54909 2 246 3.75E-96 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_07590 72f3852b7f9ba79de211f8ca5f578ce5 247 Pfam PF06778 Chlorite dismutase 33 235 3.2E-79 T 15-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase C2I28_07590 72f3852b7f9ba79de211f8ca5f578ce5 247 Hamap MF_01442 Putative heme-dependent peroxidase . 1 247 57.825 T 15-10-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family C2I28_07590 72f3852b7f9ba79de211f8ca5f578ce5 247 Gene3D G3DSA:3.30.70.1030 1 136 9.0E-57 T 15-10-2018 C2I28_07590 72f3852b7f9ba79de211f8ca5f578ce5 247 Gene3D G3DSA:3.30.70.1100 137 247 1.1E-48 T 15-10-2018 C2I28_00550 b4ff64269bbb7fad2cd669adfdf87b43 46 Pfam PF12841 YvrJ protein family 7 40 9.3E-13 T 15-10-2018 IPR024419 Protein of unknown function YvrJ C2I28_03125 cfcc21bf5d5016c9ffeb363103369d4c 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 1.4E-48 T 15-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 C2I28_03125 cfcc21bf5d5016c9ffeb363103369d4c 224 PIRSF PIRSF000032 2 224 2.0E-102 T 15-10-2018 C2I28_03125 cfcc21bf5d5016c9ffeb363103369d4c 224 Gene3D G3DSA:1.20.810.10 1 224 3.2E-89 T 15-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 C2I28_03125 cfcc21bf5d5016c9ffeb363103369d4c 224 SUPERFAMILY SSF81342 6 224 6.28E-61 T 15-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 C2I28_10460 1f28fbd30223a2f3eeb3fde2ba31bf2e 311 SUPERFAMILY SSF161098 72 298 1.24E-58 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_10460 1f28fbd30223a2f3eeb3fde2ba31bf2e 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 306 1.2E-14 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_10460 1f28fbd30223a2f3eeb3fde2ba31bf2e 311 Gene3D G3DSA:1.10.3720.10 68 309 4.9E-68 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_00435 b67d54ab1eda23b2e081af9ee7f705d1 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 202 9.2E-17 T 15-10-2018 C2I28_00435 b67d54ab1eda23b2e081af9ee7f705d1 247 SUPERFAMILY SSF56784 4 237 6.75E-26 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_00435 b67d54ab1eda23b2e081af9ee7f705d1 247 Gene3D G3DSA:3.40.50.1000 5 211 8.1E-57 T 15-10-2018 IPR023214 HAD superfamily C2I28_00435 b67d54ab1eda23b2e081af9ee7f705d1 247 Gene3D G3DSA:1.10.150.240 18 104 8.1E-57 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_14940 1ade09613abb6dc8ae6b69cda43e6c87 338 SUPERFAMILY SSF55797 214 333 1.24E-20 T 15-10-2018 IPR035940 CAP superfamily C2I28_14940 1ade09613abb6dc8ae6b69cda43e6c87 338 Gene3D G3DSA:3.40.33.10 12 334 7.2E-105 T 15-10-2018 IPR035940 CAP superfamily C2I28_14940 1ade09613abb6dc8ae6b69cda43e6c87 338 Pfam PF00188 Cysteine-rich secretory protein family 222 331 1.6E-15 T 15-10-2018 IPR014044 CAP domain C2I28_14940 1ade09613abb6dc8ae6b69cda43e6c87 338 Pfam PF14504 CAP-associated N-terminal 51 190 2.8E-50 T 15-10-2018 IPR029410 CAP-associated domain C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 15-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 Pfam PF00085 Thioredoxin 3 103 2.0E-35 T 15-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 PIRSF PIRSF000077 1 104 1.3E-44 T 15-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 PRINTS PR00421 Thioredoxin family signature 28 37 4.8E-10 T 15-10-2018 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 PRINTS PR00421 Thioredoxin family signature 20 28 4.8E-10 T 15-10-2018 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 PRINTS PR00421 Thioredoxin family signature 68 79 4.8E-10 T 15-10-2018 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 Gene3D G3DSA:3.40.30.10 1 104 2.4E-38 T 15-10-2018 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 3.1E-42 T 15-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 C2I28_05195 84531c835d12fb469a178e341c01ee5d 104 SUPERFAMILY SSF52833 3 103 2.01E-40 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 2.1E-136 T 15-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 Pfam PF04204 Homoserine O-succinyltransferase 2 300 8.1E-139 T 15-10-2018 IPR033752 MetA family C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 SUPERFAMILY SSF52317 17 298 2.7E-99 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 300 42.863 T 15-10-2018 IPR033752 MetA family C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 PIRSF PIRSF000450 1 303 1.8E-147 T 15-10-2018 IPR033752 MetA family C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 290 2.0E-100 T 15-10-2018 C2I28_17725 ffb88fa31d0b262c5745bc0029e03659 303 Gene3D G3DSA:3.40.50.880 1 301 4.5E-127 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_25980 a7e4be28186381d48add6e808be5cc2b 439 Pfam PF07690 Major Facilitator Superfamily 19 386 1.9E-56 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_25980 a7e4be28186381d48add6e808be5cc2b 439 Gene3D G3DSA:1.20.1250.20 229 427 5.7E-31 T 15-10-2018 C2I28_25980 a7e4be28186381d48add6e808be5cc2b 439 PIRSF PIRSF002808 2 436 1.5E-40 T 15-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I28_25980 a7e4be28186381d48add6e808be5cc2b 439 Gene3D G3DSA:1.20.1250.20 5 203 1.6E-48 T 15-10-2018 C2I28_25980 a7e4be28186381d48add6e808be5cc2b 439 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 23 420 5.8E-132 T 15-10-2018 C2I28_25980 a7e4be28186381d48add6e808be5cc2b 439 SUPERFAMILY SSF103473 7 422 8.5E-82 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 14 121 5.8E-29 T 15-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 Gene3D G3DSA:1.10.1060.10 118 252 9.5E-28 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 159 170 - T 15-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 Pfam PF13237 4Fe-4S dicluster domain 153 227 6.9E-9 T 15-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 Gene3D G3DSA:3.10.20.30 2 116 2.0E-31 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 SUPERFAMILY SSF46548 118 243 8.72E-27 T 15-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 15 238 1.0E-40 T 15-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 C2I28_05165 07411c7d8d0f694928fb382ca1b90041 257 SUPERFAMILY SSF54292 9 116 3.63E-22 T 15-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I28_16950 fd25210bf7af28b66a3666e2f77e538e 187 SUPERFAMILY SSF160631 20 169 1.31E-15 T 15-10-2018 C2I28_16950 fd25210bf7af28b66a3666e2f77e538e 187 Pfam PF14568 SMI1-KNR4 cell-wall 27 165 4.7E-12 T 15-10-2018 C2I28_16950 fd25210bf7af28b66a3666e2f77e538e 187 SMART SM00860 24 167 2.8E-5 T 15-10-2018 IPR018958 Knr4/Smi1-like domain C2I28_16950 fd25210bf7af28b66a3666e2f77e538e 187 Gene3D G3DSA:3.40.1580.10 5 172 3.0E-18 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_06375 3ce178928f9facc33882ee3e31a0e3d0 107 Pfam PF14068 Putative membrane protein 8 107 2.2E-41 T 15-10-2018 IPR025917 Putative membrane protein YuiB C2I28_11330 cb8a3c5af07ce04248de447372c4e2ce 419 Pfam PF01435 Peptidase family M48 207 415 1.7E-34 T 15-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 C2I28_11330 cb8a3c5af07ce04248de447372c4e2ce 419 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 31 203 8.9E-16 T 15-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 C2I28_11330 cb8a3c5af07ce04248de447372c4e2ce 419 Gene3D G3DSA:3.30.2010.10 203 284 2.8E-26 T 15-10-2018 C2I28_13075 ee0595e1d9f7c0042bda468c156a8bda 180 PIRSF PIRSF000239 1 180 1.0E-58 T 15-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_13075 ee0595e1d9f7c0042bda468c156a8bda 180 Gene3D G3DSA:3.40.30.10 1 180 5.2E-74 T 15-10-2018 C2I28_13075 ee0595e1d9f7c0042bda468c156a8bda 180 Pfam PF00578 AhpC/TSA family 6 141 3.5E-40 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_13075 ee0595e1d9f7c0042bda468c156a8bda 180 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 180 1.1E-4 T 15-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_13075 ee0595e1d9f7c0042bda468c156a8bda 180 SUPERFAMILY SSF52833 4 178 2.08E-59 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_01550 e81c6d562b7876b3de326c0d07711db5 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 131 5.1E-54 T 15-10-2018 IPR001602 Uncharacterised protein family UPF0047 C2I28_01550 e81c6d562b7876b3de326c0d07711db5 134 PIRSF PIRSF004681 1 132 1.4E-36 T 15-10-2018 IPR001602 Uncharacterised protein family UPF0047 C2I28_01550 e81c6d562b7876b3de326c0d07711db5 134 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 2.0E-39 T 15-10-2018 IPR001602 Uncharacterised protein family UPF0047 C2I28_01550 e81c6d562b7876b3de326c0d07711db5 134 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 15-10-2018 IPR001602 Uncharacterised protein family UPF0047 C2I28_01550 e81c6d562b7876b3de326c0d07711db5 134 Gene3D G3DSA:2.60.120.460 1 132 3.2E-53 T 15-10-2018 IPR035917 YjbQ-like superfamily C2I28_01550 e81c6d562b7876b3de326c0d07711db5 134 SUPERFAMILY SSF111038 2 131 5.36E-47 T 15-10-2018 IPR035917 YjbQ-like superfamily C2I28_16660 49370f9a8d73ff56429f58b5b1c54aff 253 SUPERFAMILY SSF53335 1 238 4.14E-25 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_16660 49370f9a8d73ff56429f58b5b1c54aff 253 Pfam PF08241 Methyltransferase domain 67 161 2.9E-18 T 15-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I28_16660 49370f9a8d73ff56429f58b5b1c54aff 253 Gene3D G3DSA:3.40.50.150 54 253 5.7E-22 T 15-10-2018 C2I28_19255 977a258de0545e7b417068bcaf3ff5da 40 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 28 6.5E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_19255 977a258de0545e7b417068bcaf3ff5da 40 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 7 30 1.5E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 Gene3D G3DSA:3.40.50.720 1 127 7.1E-34 T 15-10-2018 C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 SUPERFAMILY SSF75615 111 189 3.79E-16 T 15-10-2018 C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 SUPERFAMILY SSF51735 2 97 1.63E-15 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 Gene3D G3DSA:1.10.8.610 128 202 1.4E-28 T 15-10-2018 C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 169 5.2E-26 T 15-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 Pfam PF13241 Putative NAD(P)-binding 4 112 1.1E-22 T 15-10-2018 C2I28_06180 23033e87c8bad0ea3b58c6fe3f272159 202 Pfam PF14824 Sirohaem biosynthesis protein central 116 142 3.2E-9 T 15-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 C2I28_21530 5398abb612636fb1eab91976a6418db2 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 421 1.1E-63 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_21530 5398abb612636fb1eab91976a6418db2 464 PIRSF PIRSF006603 4 457 6.2E-85 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_21530 5398abb612636fb1eab91976a6418db2 464 Pfam PF01554 MatE 247 407 8.4E-28 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_21530 5398abb612636fb1eab91976a6418db2 464 Pfam PF01554 MatE 22 181 1.5E-24 T 15-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 SMART SM00228 337 407 1.1E-12 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 Gene3D G3DSA:2.30.42.10 321 423 3.6E-27 T 15-10-2018 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 Gene3D G3DSA:2.40.10.10 204 320 1.0E-39 T 15-10-2018 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 Pfam PF13365 Trypsin-like peptidase domain 139 280 3.2E-30 T 15-10-2018 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 PRINTS PR00834 HtrA/DegQ protease family signature 172 192 1.5E-37 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 1.5E-37 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 PRINTS PR00834 HtrA/DegQ protease family signature 364 376 1.5E-37 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 PRINTS PR00834 HtrA/DegQ protease family signature 213 237 1.5E-37 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 PRINTS PR00834 HtrA/DegQ protease family signature 151 163 1.5E-37 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 PRINTS PR00834 HtrA/DegQ protease family signature 273 290 1.5E-37 T 15-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 Gene3D G3DSA:2.40.10.10 75 202 7.4E-26 T 15-10-2018 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 SUPERFAMILY SSF50156 303 416 3.15E-20 T 15-10-2018 IPR036034 PDZ superfamily GO:0005515 C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 SUPERFAMILY SSF50494 101 314 6.75E-59 T 15-10-2018 IPR009003 Peptidase S1, PA clan C2I28_01125 51f7e50df91837249ebd4191daf5fd47 424 Pfam PF13180 PDZ domain 318 416 1.8E-20 T 15-10-2018 IPR001478 PDZ domain GO:0005515 C2I28_24075 5873d778ca04cdcb3ed04492254406e8 218 Pfam PF06161 Protein of unknown function (DUF975) 123 211 4.5E-24 T 15-10-2018 IPR010380 Protein of unknown function DUF975 C2I28_24075 5873d778ca04cdcb3ed04492254406e8 218 Pfam PF06161 Protein of unknown function (DUF975) 2 130 1.3E-8 T 15-10-2018 IPR010380 Protein of unknown function DUF975 C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 Gene3D G3DSA:1.20.81.30 201 310 1.4E-8 T 15-10-2018 C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 Pfam PF00482 Type II secretion system (T2SS), protein F 20 139 7.1E-16 T 15-10-2018 IPR018076 Type II secretion system F domain C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 Pfam PF00482 Type II secretion system (T2SS), protein F 220 340 9.1E-13 T 15-10-2018 IPR018076 Type II secretion system F domain C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 15 27 7.4E-9 T 15-10-2018 IPR003004 GspF/PilC family C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 111 139 7.4E-9 T 15-10-2018 IPR003004 GspF/PilC family C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 329 348 7.4E-9 T 15-10-2018 IPR003004 GspF/PilC family C2I28_04030 cbcf88e9afec47932abe41e79cfe7fe7 348 Gene3D G3DSA:1.20.81.30 5 116 5.3E-15 T 15-10-2018 C2I28_24875 b020db95fd6b7d8a135d7f9b99b8850b 207 SUPERFAMILY SSF50475 11 177 4.32E-36 T 15-10-2018 C2I28_24875 b020db95fd6b7d8a135d7f9b99b8850b 207 Gene3D G3DSA:2.30.110.10 1 202 2.6E-76 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_24875 b020db95fd6b7d8a135d7f9b99b8850b 207 PIRSF PIRSF010372 1 203 4.3E-63 T 15-10-2018 IPR007396 Transcriptional regulator PAI 2-type C2I28_24875 b020db95fd6b7d8a135d7f9b99b8850b 207 Pfam PF04299 Putative FMN-binding domain 1 159 1.7E-53 T 15-10-2018 IPR007396 Transcriptional regulator PAI 2-type C2I28_20080 7377a1083cf75fa96e55ee1e61e0c6ab 262 SMART SM00849 35 213 0.0043 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_20080 7377a1083cf75fa96e55ee1e61e0c6ab 262 SUPERFAMILY SSF56281 3 258 2.75E-28 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_20080 7377a1083cf75fa96e55ee1e61e0c6ab 262 Gene3D G3DSA:3.60.15.10 1 258 9.6E-47 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_20080 7377a1083cf75fa96e55ee1e61e0c6ab 262 Pfam PF12706 Beta-lactamase superfamily domain 49 228 1.8E-18 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_15805 6e6d03516dbc61100c536fb8a10f1298 406 Gene3D G3DSA:1.20.1250.20 2 203 8.2E-45 T 15-10-2018 C2I28_15805 6e6d03516dbc61100c536fb8a10f1298 406 Gene3D G3DSA:1.20.1250.20 204 401 1.2E-29 T 15-10-2018 C2I28_15805 6e6d03516dbc61100c536fb8a10f1298 406 Pfam PF07690 Major Facilitator Superfamily 14 267 1.2E-39 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_15805 6e6d03516dbc61100c536fb8a10f1298 406 SUPERFAMILY SSF103473 3 391 2.22E-82 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_03465 6e6091c0c33c9f4e0b0b5053f13f9a99 117 Gene3D G3DSA:3.40.630.30 5 114 2.0E-13 T 15-10-2018 C2I28_03465 6e6091c0c33c9f4e0b0b5053f13f9a99 117 SUPERFAMILY SSF55729 7 98 1.1E-13 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_03465 6e6091c0c33c9f4e0b0b5053f13f9a99 117 Pfam PF13673 Acetyltransferase (GNAT) domain 30 111 2.8E-9 T 15-10-2018 IPR000182 GNAT domain C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 Gene3D G3DSA:3.30.310.10 1 87 2.6E-28 T 15-10-2018 IPR012295 TBP domain superfamily C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 294 2.4E-94 T 15-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 Pfam PF01351 Ribonuclease HII 90 295 8.2E-50 T 15-10-2018 IPR024567 Ribonuclease HII/HIII domain C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 PIRSF PIRSF037748 1 303 1.8E-119 T 15-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 Gene3D G3DSA:3.30.420.10 88 304 1.5E-79 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 Pfam PF11858 Domain of unknown function (DUF3378) 3 75 8.5E-27 T 15-10-2018 IPR024568 Ribonuclease HIII, N-terminal C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 SUPERFAMILY SSF53098 88 301 9.56E-52 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_05260 ea8632f4f192712941a036ce7c37488c 304 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 302 34.537 T 15-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 Pfam PF03466 LysR substrate binding domain 87 282 1.5E-30 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 SUPERFAMILY SSF53850 87 284 6.92E-30 T 15-10-2018 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 4.1E-16 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 Gene3D G3DSA:3.40.190.290 82 284 4.0E-70 T 15-10-2018 C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 SUPERFAMILY SSF46785 1 110 4.47E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12465 32d10f0431829c45fa3e7bed1b6ad6cb 290 Gene3D G3DSA:1.10.10.10 1 81 1.0E-19 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 182 25.554 T 15-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 Pfam PF01386 Ribosomal L25p family 5 91 4.4E-22 T 15-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 Gene3D G3DSA:2.170.120.20 97 188 2.3E-28 T 15-10-2018 IPR037121 Ribosomal protein L25, C-terminal C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 3 91 3.0E-24 T 15-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 182 3.3E-25 T 15-10-2018 IPR020057 Ribosomal protein L25, beta domain C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 179 5.8E-51 T 15-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 Gene3D G3DSA:2.40.240.10 2 94 3.8E-26 T 15-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I28_08365 959f02bf4ad9e155b7e5ab7d35829880 209 SUPERFAMILY SSF50715 1 188 2.62E-53 T 15-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 C2I28_10145 bbcb3e38f20344fdd14c9ba4872cd74d 261 Pfam PF06182 ABC-2 family transporter protein 33 260 1.8E-53 T 15-10-2018 IPR010390 Protein of unknown function DUF990 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 Gene3D G3DSA:1.20.1250.20 198 388 4.6E-20 T 15-10-2018 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 131 152 1.8E-5 T 15-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 1.8E-5 T 15-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 7 29 1.8E-5 T 15-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 PRINTS PR01988 Putative bacilysin exporter bacE signature 277 300 1.8E-5 T 15-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 Gene3D G3DSA:1.20.1250.20 1 197 1.4E-24 T 15-10-2018 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 SUPERFAMILY SSF103473 3 387 1.44E-52 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 Pfam PF07690 Major Facilitator Superfamily 228 379 1.5E-15 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_05805 5abd5ab5049e312c8f56963c8559dd4a 395 Pfam PF07690 Major Facilitator Superfamily 8 192 2.2E-22 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_02810 f7af194e0c55fb7ec98468ab756968c5 573 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 447 1.2E-161 T 15-10-2018 C2I28_02810 f7af194e0c55fb7ec98468ab756968c5 573 Gene3D G3DSA:3.40.970.40 247 292 5.8E-15 T 15-10-2018 C2I28_02810 f7af194e0c55fb7ec98468ab756968c5 573 Gene3D G3DSA:2.30.310.10 5 170 9.4E-67 T 15-10-2018 C2I28_02810 f7af194e0c55fb7ec98468ab756968c5 573 Pfam PF05670 Domain of unknown function (DUF814) 457 541 3.3E-31 T 15-10-2018 IPR008532 Domain of unknown function DUF814 C2I28_02810 f7af194e0c55fb7ec98468ab756968c5 573 Gene3D G3DSA:1.10.8.50 171 239 2.0E-24 T 15-10-2018 C2I28_17210 c523466df049206c97612cef6a322098 405 Pfam PF01266 FAD dependent oxidoreductase 3 390 2.0E-66 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_17210 c523466df049206c97612cef6a322098 405 SUPERFAMILY SSF51905 1 281 3.24E-47 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_05225 c7e58171f061f8f254f964fe31e643ed 563 Gene3D G3DSA:3.40.50.12780 11 452 2.8E-130 T 15-10-2018 C2I28_05225 c7e58171f061f8f254f964fe31e643ed 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 213 224 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_05225 c7e58171f061f8f254f964fe31e643ed 563 Gene3D G3DSA:3.30.300.310 457 561 2.3E-33 T 15-10-2018 C2I28_05225 c7e58171f061f8f254f964fe31e643ed 563 Pfam PF00501 AMP-binding enzyme 31 460 6.6E-113 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_05225 c7e58171f061f8f254f964fe31e643ed 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 545 1.2E-20 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_05225 c7e58171f061f8f254f964fe31e643ed 563 SUPERFAMILY SSF56801 14 555 5.76E-160 T 15-10-2018 C2I28_12295 75c885239ae169b06f8f27ad612c9a0b 282 Pfam PF00809 Pterin binding enzyme 26 259 3.4E-88 T 15-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_12295 75c885239ae169b06f8f27ad612c9a0b 282 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 25 273 1.7E-99 T 15-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 C2I28_12295 75c885239ae169b06f8f27ad612c9a0b 282 Gene3D G3DSA:3.20.20.20 5 279 9.4E-114 T 15-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_12295 75c885239ae169b06f8f27ad612c9a0b 282 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 59 72 - T 15-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_12295 75c885239ae169b06f8f27ad612c9a0b 282 SUPERFAMILY SSF51717 11 276 2.09E-100 T 15-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 C2I28_01895 7c48da2c153c41b664f4c1fd2f371669 506 SUPERFAMILY SSF53383 42 492 2.16E-121 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_01895 7c48da2c153c41b664f4c1fd2f371669 506 Gene3D G3DSA:3.90.1150.170 46 484 9.1E-139 T 15-10-2018 C2I28_01895 7c48da2c153c41b664f4c1fd2f371669 506 Gene3D G3DSA:3.40.640.10 113 362 9.1E-139 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_01895 7c48da2c153c41b664f4c1fd2f371669 506 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 59 418 7.8E-72 T 15-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 C2I28_01895 7c48da2c153c41b664f4c1fd2f371669 506 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 305 326 - T 15-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 142 204 8.0E-17 T 15-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 Gene3D G3DSA:3.40.50.10240 1 214 5.3E-73 T 15-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 SUPERFAMILY SSF63862 130 209 5.75E-14 T 15-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 207 9.1E-61 T 15-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 SMART SM00983 139 205 1.2E-20 T 15-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 SUPERFAMILY SSF63999 3 128 7.85E-32 T 15-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_02730 95101141c5d3bc24fdafa3d9a9e49c52 215 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 24 125 3.4E-20 T 15-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 C2I28_07130 f902ff2901181f0a391b1f3bbff26658 293 Pfam PF00700 Bacterial flagellin C-terminal helical region 211 292 1.1E-5 T 15-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I28_07130 f902ff2901181f0a391b1f3bbff26658 293 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 185 9.2E-57 T 15-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 C2I28_07130 f902ff2901181f0a391b1f3bbff26658 293 SUPERFAMILY SSF64518 1 293 1.02E-66 T 15-10-2018 C2I28_07130 f902ff2901181f0a391b1f3bbff26658 293 Gene3D G3DSA:1.20.1330.10 40 239 4.6E-45 T 15-10-2018 C2I28_07130 f902ff2901181f0a391b1f3bbff26658 293 Pfam PF00669 Bacterial flagellin N-terminal helical region 7 139 1.0E-21 T 15-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 C2I28_09800 7f74484a399f9b0cbc911715714c26ae 105 SUPERFAMILY SSF140453 20 93 4.45E-6 T 15-10-2018 IPR036689 ESAT-6-like superfamily C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.8E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.8E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.8E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.0E-23 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.0E-23 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.0E-23 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.0E-23 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.0E-23 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 PIRSF PIRSF000126 1 258 3.5E-75 T 15-10-2018 C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 SUPERFAMILY SSF51735 2 253 5.28E-63 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 Pfam PF00106 short chain dehydrogenase 6 192 1.7E-50 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_18520 8bdc2e18c4251c00c86bf11c1aa25abd 259 Gene3D G3DSA:3.40.50.720 2 256 2.5E-62 T 15-10-2018 C2I28_17395 d11a14397602c880943fdcf3b5eaeda1 507 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 35 493 1.0E-142 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_17395 d11a14397602c880943fdcf3b5eaeda1 507 PIRSF PIRSF005690 21 506 1.3E-139 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_21345 c525155e642697c49121b6c8ac653ca7 334 SUPERFAMILY SSF51679 9 330 2.88E-88 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_21345 c525155e642697c49121b6c8ac653ca7 334 Pfam PF00296 Luciferase-like monooxygenase 26 307 2.0E-37 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_21345 c525155e642697c49121b6c8ac653ca7 334 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 10 331 1.4E-140 T 15-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 C2I28_21345 c525155e642697c49121b6c8ac653ca7 334 Gene3D G3DSA:3.20.20.30 5 334 7.9E-102 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_06020 337ac888c6ae8b3f8d9dba86684ebc74 265 Gene3D G3DSA:3.60.160.10 1 248 1.5E-101 T 15-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily C2I28_06020 337ac888c6ae8b3f8d9dba86684ebc74 265 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 8 228 1.2E-30 T 15-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 C2I28_06020 337ac888c6ae8b3f8d9dba86684ebc74 265 SUPERFAMILY SSF51219 6 243 5.23E-83 T 15-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily C2I28_06020 337ac888c6ae8b3f8d9dba86684ebc74 265 Pfam PF01987 Mitochondrial biogenesis AIM24 8 226 9.0E-68 T 15-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 SUPERFAMILY SSF46894 131 232 1.62E-32 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 7.1E-30 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 SUPERFAMILY SSF52172 2 132 1.14E-43 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 SMART SM00448 3 114 8.4E-49 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 Pfam PF00072 Response regulator receiver domain 6 114 1.7E-30 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 Gene3D G3DSA:1.10.10.10 138 237 4.6E-36 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 SMART SM00862 155 231 2.4E-29 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_05385 966658761ec01cdb5ff9f9082ce2c102 238 Gene3D G3DSA:3.40.50.2300 2 137 1.4E-40 T 15-10-2018 C2I28_11350 6d54aee92a060215599e04fca6728e0a 205 Pfam PF09335 SNARE associated Golgi protein 43 161 3.8E-21 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_05555 b1fd2eecf347925eb8c639493519b7c7 530 Gene3D G3DSA:3.20.20.140 61 487 3.2E-130 T 15-10-2018 C2I28_05555 b1fd2eecf347925eb8c639493519b7c7 530 SUPERFAMILY SSF51556 60 487 2.24E-34 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_05555 b1fd2eecf347925eb8c639493519b7c7 530 SUPERFAMILY SSF51338 3 528 1.63E-11 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_05555 b1fd2eecf347925eb8c639493519b7c7 530 Gene3D G3DSA:3.10.310.70 79 196 3.2E-130 T 15-10-2018 C2I28_05555 b1fd2eecf347925eb8c639493519b7c7 530 Gene3D G3DSA:2.30.40.10 7 504 3.2E-130 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_05555 b1fd2eecf347925eb8c639493519b7c7 530 Pfam PF07969 Amidohydrolase family 50 528 5.2E-117 T 15-10-2018 IPR013108 Amidohydrolase 3 C2I28_17795 3fa4890dfa975a712d3f0a4334e6ca51 328 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 14 318 2.6E-80 T 15-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 C2I28_17795 3fa4890dfa975a712d3f0a4334e6ca51 328 Pfam PF03186 CobD/Cbib protein 15 301 6.9E-101 T 15-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 C2I28_17795 3fa4890dfa975a712d3f0a4334e6ca51 328 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 328 90.761 T 15-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 C2I28_06570 133364a8d3be18e01e8b04f875878bb8 81 ProDom PD058325 YUSG BH3483 6 81 1.0E-13 T 15-10-2018 IPR020140 Uncharacterised protein family YusG C2I28_06570 133364a8d3be18e01e8b04f875878bb8 81 Pfam PF10830 Protein of unknown function (DUF2553) 5 81 8.7E-32 T 15-10-2018 IPR020140 Uncharacterised protein family YusG C2I28_01690 ec01ce5459a1d7e329ec6e50f63a429c 482 Pfam PF01740 STAS domain 392 477 7.8E-9 T 15-10-2018 IPR002645 STAS domain C2I28_01690 ec01ce5459a1d7e329ec6e50f63a429c 482 ProSitePatterns PS01130 SLC26A transporters signature. 42 63 - T 15-10-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 C2I28_01690 ec01ce5459a1d7e329ec6e50f63a429c 482 Gene3D G3DSA:3.30.750.24 381 477 5.9E-27 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_01690 ec01ce5459a1d7e329ec6e50f63a429c 482 SUPERFAMILY SSF52091 387 479 1.39E-12 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_01690 ec01ce5459a1d7e329ec6e50f63a429c 482 Pfam PF00916 Sulfate permease family 163 354 2.4E-34 T 15-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I28_01690 ec01ce5459a1d7e329ec6e50f63a429c 482 Pfam PF00916 Sulfate permease family 14 143 1.1E-27 T 15-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I28_23815 165088bd1f5b2ba7b40d69af99d438cd 207 PIRSF PIRSF006324 1 207 1.9E-56 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_23815 165088bd1f5b2ba7b40d69af99d438cd 207 Pfam PF01810 LysE type translocator 16 204 1.5E-36 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_09120 d47a354ba833a5cbae22badd517faadd 323 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 4 306 5.6E-69 T 15-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I28_09120 d47a354ba833a5cbae22badd517faadd 323 Gene3D G3DSA:3.20.20.150 4 312 5.7E-96 T 15-10-2018 C2I28_09120 d47a354ba833a5cbae22badd517faadd 323 Pfam PF03851 UV-endonuclease UvdE 7 277 3.4E-88 T 15-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I28_09120 d47a354ba833a5cbae22badd517faadd 323 SUPERFAMILY SSF51658 94 276 3.91E-12 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 SUPERFAMILY SSF88946 22 131 1.44E-35 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 6.6E-136 T 15-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 Gene3D G3DSA:1.20.120.1810 19 131 3.0E-25 T 15-10-2018 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 Gene3D G3DSA:1.10.10.10 168 239 1.1E-13 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 PIRSF PIRSF000770 10 239 3.7E-77 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 6.3E-36 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 7.1E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 7.1E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 7.1E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 7.1E-12 T 15-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 Pfam PF04542 Sigma-70 region 2 62 131 1.8E-18 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 Pfam PF04545 Sigma-70, region 4 180 233 1.8E-17 T 15-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 C2I28_02925 06b347bada9f3a1a4e140f99acc20ab5 239 SUPERFAMILY SSF88659 143 237 1.08E-21 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_06670 b10dc52831eb8fa7d60c470473da0cbe 143 Gene3D G3DSA:1.20.1290.10 3 132 7.2E-38 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_06670 b10dc52831eb8fa7d60c470473da0cbe 143 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 122 3.0E-16 T 15-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_06670 b10dc52831eb8fa7d60c470473da0cbe 143 SUPERFAMILY SSF69118 28 132 3.78E-29 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 4 331 4.9E-140 T 15-10-2018 IPR030827 Inositol 2-dehydrogenase C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 SUPERFAMILY SSF55347 128 291 5.63E-35 T 15-10-2018 C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 Gene3D G3DSA:3.40.50.720 6 322 5.2E-107 T 15-10-2018 C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 Gene3D G3DSA:3.30.360.10 142 272 5.2E-107 T 15-10-2018 C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 SUPERFAMILY SSF51735 4 150 1.46E-47 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 231 3.2E-7 T 15-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 C2I28_10595 b455916486f4f05d0bb6f14b460081fb 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 8.3E-27 T 15-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 308 46.228 T 15-10-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 SMART SM01131 181 307 9.5E-51 T 15-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 Gene3D G3DSA:3.90.1640.10 1 188 2.9E-81 T 15-10-2018 C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 SUPERFAMILY SSF64182 3 306 3.4E-83 T 15-10-2018 IPR038763 DHH phosphoesterase superfamily C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 Pfam PF01368 DHH family 3 146 5.1E-31 T 15-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 Gene3D G3DSA:3.10.310.20 190 308 1.4E-37 T 15-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_20665 a01fc9b0323caec459bb48f5b6ca52c9 308 Pfam PF02833 DHHA2 domain 183 305 5.4E-19 T 15-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_07675 8e1aaccf641aeb1d9053abfbf7abc705 366 Gene3D G3DSA:3.40.50.2000 21 357 2.7E-60 T 15-10-2018 C2I28_07675 8e1aaccf641aeb1d9053abfbf7abc705 366 Pfam PF13439 Glycosyltransferase Family 4 65 157 4.9E-7 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_07675 8e1aaccf641aeb1d9053abfbf7abc705 366 SUPERFAMILY SSF53756 1 358 1.88E-64 T 15-10-2018 C2I28_07675 8e1aaccf641aeb1d9053abfbf7abc705 366 Gene3D G3DSA:3.40.50.2000 159 347 2.7E-60 T 15-10-2018 C2I28_07675 8e1aaccf641aeb1d9053abfbf7abc705 366 Pfam PF00534 Glycosyl transferases group 1 172 340 3.7E-29 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_08490 5a48e20608f9caa4217fec5dfcf66319 287 SUPERFAMILY SSF56752 1 274 2.09E-76 T 15-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 C2I28_08490 5a48e20608f9caa4217fec5dfcf66319 287 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 15-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 C2I28_08490 5a48e20608f9caa4217fec5dfcf66319 287 Gene3D G3DSA:3.20.10.10 125 275 3.6E-45 T 15-10-2018 C2I28_08490 5a48e20608f9caa4217fec5dfcf66319 287 Gene3D G3DSA:3.30.470.10 1 123 7.9E-37 T 15-10-2018 C2I28_08490 5a48e20608f9caa4217fec5dfcf66319 287 Pfam PF01063 Amino-transferase class IV 29 252 1.9E-59 T 15-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 Gene3D G3DSA:1.10.287.1080 229 352 6.0E-44 T 15-10-2018 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 Gene3D G3DSA:3.40.1010.10 1 119 8.8E-11 T 15-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 Gene3D G3DSA:1.10.287.1080 356 485 2.6E-43 T 15-10-2018 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 TIGRFAM TIGR00444 mazG: MazG family protein 239 482 4.6E-104 T 15-10-2018 IPR011551 NTP pyrophosphohydrolase MazG C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 PIRSF PIRSF002845 1 485 6.0E-224 T 15-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 206 9.4E-22 T 15-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 SUPERFAMILY SSF53790 3 263 3.34E-31 T 15-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 392 451 4.3E-9 T 15-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 3.0E-29 T 15-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 SUPERFAMILY SSF101386 231 332 4.36E-25 T 15-10-2018 C2I28_08395 d9d55d8cfd9a672daa47781d5b9010a3 486 SUPERFAMILY SSF101386 365 461 6.54E-24 T 15-10-2018 C2I28_19920 9eff324f64040b54e661a49c0fdb2b77 461 PIRSF PIRSF000521 8 398 1.2E-36 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_19920 9eff324f64040b54e661a49c0fdb2b77 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_19920 9eff324f64040b54e661a49c0fdb2b77 461 SUPERFAMILY SSF53383 18 444 2.62E-116 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_19920 9eff324f64040b54e661a49c0fdb2b77 461 Pfam PF00202 Aminotransferase class-III 19 443 8.1E-92 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_19920 9eff324f64040b54e661a49c0fdb2b77 461 Gene3D G3DSA:3.40.640.10 53 333 1.6E-144 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_19920 9eff324f64040b54e661a49c0fdb2b77 461 Gene3D G3DSA:3.90.1150.10 19 444 1.6E-144 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 SUPERFAMILY SSF46785 4 69 8.05E-15 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 Gene3D G3DSA:1.10.10.10 2 69 1.5E-17 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 Gene3D G3DSA:3.40.640.10 115 334 9.8E-90 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 3.3E-10 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 SMART SM00345 8 67 3.3E-12 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 Pfam PF00155 Aminotransferase class I and II 91 436 1.8E-27 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 Gene3D G3DSA:3.90.1150.10 75 440 9.8E-90 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_23020 dd8223d8dd5a1a6116bc135b6bdbc5b6 458 SUPERFAMILY SSF53383 65 440 1.79E-74 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_12310 6c768a46a636b1fbd9964131446d28e4 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.8E-17 T 15-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I28_12310 6c768a46a636b1fbd9964131446d28e4 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 395 1.7E-48 T 15-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I28_12310 6c768a46a636b1fbd9964131446d28e4 397 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 395 2.3E-134 T 15-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 C2I28_12170 adb643fcb15b83192a64c7760c7ebbcf 100 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 93 3.0E-27 T 15-10-2018 IPR009662 Malonate decarboxylase delta subunit C2I28_12170 adb643fcb15b83192a64c7760c7ebbcf 100 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 16 93 7.0E-23 T 15-10-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein C2I28_12170 adb643fcb15b83192a64c7760c7ebbcf 100 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 99 36.812 T 15-10-2018 IPR009662 Malonate decarboxylase delta subunit C2I28_12170 adb643fcb15b83192a64c7760c7ebbcf 100 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 94 6.3E-34 T 15-10-2018 IPR009662 Malonate decarboxylase delta subunit C2I28_09785 61bbe32cbf019b45cf276941c222b413 250 Pfam PF01740 STAS domain 148 234 1.4E-11 T 15-10-2018 IPR002645 STAS domain C2I28_09785 61bbe32cbf019b45cf276941c222b413 250 Gene3D G3DSA:3.30.750.24 134 248 3.7E-22 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09785 61bbe32cbf019b45cf276941c222b413 250 SUPERFAMILY SSF52091 138 245 2.35E-15 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_25320 470a3a940e284e616dcc4ef300fe43a0 385 Gene3D G3DSA:3.30.420.40 203 350 3.4E-8 T 15-10-2018 C2I28_15715 f20bacb3005259a25225eb04ddb7c946 287 Gene3D G3DSA:1.10.3720.10 87 277 3.0E-35 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15715 f20bacb3005259a25225eb04ddb7c946 287 SUPERFAMILY SSF161098 90 273 7.72E-40 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15715 f20bacb3005259a25225eb04ddb7c946 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 269 1.8E-24 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 SMART SM00347 31 131 2.3E-16 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 SUPERFAMILY SSF46785 34 145 4.92E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 Pfam PF12802 MarR family 37 94 3.5E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 Gene3D G3DSA:1.10.10.10 2 150 5.1E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 2.3E-8 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 2.3E-8 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12765 278c245d3c4418fe83a7cc24d0976d17 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 2.3E-8 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_13865 c049deef1310698defabc95ce3767faa 278 Gene3D G3DSA:1.20.1080.10 2 264 4.3E-87 T 15-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I28_13865 c049deef1310698defabc95ce3767faa 278 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 160 170 - T 15-10-2018 IPR024002 Formate/nitrite transporter, conserved site C2I28_13865 c049deef1310698defabc95ce3767faa 278 Pfam PF01226 Formate/nitrite transporter 8 251 2.2E-71 T 15-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 ProSitePatterns PS00217 Sugar transport proteins signature 2. 321 346 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 Gene3D G3DSA:1.20.1250.20 1 399 8.6E-68 T 15-10-2018 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 SUPERFAMILY SSF103473 1 401 6.02E-68 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 PRINTS PR01035 Tetracycline resistance protein signature 18 34 5.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 PRINTS PR01035 Tetracycline resistance protein signature 80 104 5.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 PRINTS PR01035 Tetracycline resistance protein signature 310 330 5.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 PRINTS PR01035 Tetracycline resistance protein signature 139 161 5.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 PRINTS PR01035 Tetracycline resistance protein signature 345 368 5.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 PRINTS PR01035 Tetracycline resistance protein signature 167 187 5.8E-14 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_15370 4dbba9513b42e0ab8fcf03b0bcf153e7 413 Pfam PF07690 Major Facilitator Superfamily 17 365 6.9E-57 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_22230 5f50c01b9abc5e44edfac7aec7e6391c 390 Gene3D G3DSA:3.40.50.1970 4 186 5.9E-50 T 15-10-2018 C2I28_22230 5f50c01b9abc5e44edfac7aec7e6391c 390 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 267 287 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_22230 5f50c01b9abc5e44edfac7aec7e6391c 390 SUPERFAMILY SSF56796 1 388 6.02E-108 T 15-10-2018 C2I28_22230 5f50c01b9abc5e44edfac7aec7e6391c 390 Gene3D G3DSA:1.20.1090.10 187 389 1.5E-45 T 15-10-2018 C2I28_22230 5f50c01b9abc5e44edfac7aec7e6391c 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 366 6.2E-96 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 SUPERFAMILY SSF51569 1 220 2.83E-72 T 15-10-2018 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 Hamap MF_00494 Probable transaldolase [tal]. 1 221 44.031 T 15-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 217 1.8E-55 T 15-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 Gene3D G3DSA:3.20.20.70 1 222 4.7E-85 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 2.4E-80 T 15-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 C2I28_24240 9c03bcd6196abf698b610f55fb4e71b0 222 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 15-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 4.7E-182 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 SUPERFAMILY SSF144052 4 409 6.02E-156 T 15-10-2018 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 Gene3D G3DSA:3.40.1830.10 1 180 1.7E-71 T 15-10-2018 IPR035097 Peptidase M29, N-terminal C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_22460 605b97b4e9cb9a00de7ff9a665302d25 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 9.5E-78 T 15-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 Pfam PF10114 Sensory domain found in PocR 11 179 3.0E-46 T 15-10-2018 IPR018771 PocR domain C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 Pfam PF12833 Helix-turn-helix domain 264 341 6.4E-16 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 SMART SM00342 257 340 1.1E-21 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 294 336 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 SUPERFAMILY SSF46689 294 343 6.72E-11 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 Gene3D G3DSA:1.10.10.60 289 346 5.5E-16 T 15-10-2018 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 Gene3D G3DSA:1.10.10.60 238 288 1.2E-12 T 15-10-2018 C2I28_16740 45aecd35f71104cc8f544cbfa227a009 347 SUPERFAMILY SSF46689 240 289 1.34E-6 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_14480 2a04779c355077f3d1ed6c92d44510b7 432 Pfam PF00860 Permease family 20 390 2.3E-27 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_18025 b0cb50262e4e612ffb4c5a282d6b4707 277 Gene3D G3DSA:3.30.1330.60 108 276 6.3E-47 T 15-10-2018 IPR036737 OmpA-like domain superfamily C2I28_18025 b0cb50262e4e612ffb4c5a282d6b4707 277 Pfam PF00691 OmpA family 163 263 1.1E-15 T 15-10-2018 IPR006665 OmpA-like domain C2I28_18025 b0cb50262e4e612ffb4c5a282d6b4707 277 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 58 1.0E-21 T 15-10-2018 IPR025713 Motility protein B, N-terminal domain C2I28_18025 b0cb50262e4e612ffb4c5a282d6b4707 277 SUPERFAMILY SSF103088 150 271 5.23E-28 T 15-10-2018 IPR036737 OmpA-like domain superfamily C2I28_19475 6f48ee070481bf6154d54b5b6b62ddb0 158 Pfam PF00583 Acetyltransferase (GNAT) family 25 119 2.7E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_19475 6f48ee070481bf6154d54b5b6b62ddb0 158 Gene3D G3DSA:3.40.630.30 3 158 1.8E-31 T 15-10-2018 C2I28_19475 6f48ee070481bf6154d54b5b6b62ddb0 158 SUPERFAMILY SSF55729 7 152 1.08E-18 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 8.7E-16 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 15-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 Gene3D G3DSA:3.30.70.920 52 142 2.2E-20 T 15-10-2018 C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 SMART SM00344 3 109 2.2E-39 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 SUPERFAMILY SSF54909 64 137 2.95E-13 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.0E-15 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.0E-15 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.0E-15 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 Gene3D G3DSA:1.10.10.10 1 50 7.0E-22 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 SUPERFAMILY SSF46785 2 61 4.4E-17 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_01115 a1c8655feae8a5b0c8b50845098989b8 151 Pfam PF01037 Lrp/AsnC ligand binding domain 69 135 8.6E-9 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_14410 dbcb6353b68ab9578dfda817443444be 373 Pfam PF03845 Spore germination protein 8 322 1.2E-43 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_14410 dbcb6353b68ab9578dfda817443444be 373 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 363 6.9E-62 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_23455 5327e567ac4bbdb35d42628aef30c811 271 Pfam PF01740 STAS domain 160 263 4.9E-12 T 15-10-2018 IPR002645 STAS domain C2I28_23455 5327e567ac4bbdb35d42628aef30c811 271 Gene3D G3DSA:3.30.750.24 154 270 5.3E-35 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_23455 5327e567ac4bbdb35d42628aef30c811 271 SUPERFAMILY SSF52091 159 268 4.51E-18 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_18820 528e182a6152985c07c77d3d587f1fab 47 SUPERFAMILY SSF47406 8 34 2.75E-7 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_18820 528e182a6152985c07c77d3d587f1fab 47 Pfam PF08671 Anti-repressor SinI 10 34 1.9E-10 T 15-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I28_23330 6328afd546d703633faa7d096e3067a5 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 25.059 T 15-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid C2I28_23330 6328afd546d703633faa7d096e3067a5 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 1.1E-29 T 15-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_23330 6328afd546d703633faa7d096e3067a5 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 15-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_23330 6328afd546d703633faa7d096e3067a5 89 SUPERFAMILY SSF57716 2 89 2.49E-32 T 15-10-2018 C2I28_23330 6328afd546d703633faa7d096e3067a5 89 Gene3D G3DSA:4.10.830.10 28 89 2.4E-26 T 15-10-2018 C2I28_16730 c36abd3867e0d708dfad103df65f0c06 219 Pfam PF00753 Metallo-beta-lactamase superfamily 25 200 1.3E-24 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_16730 c36abd3867e0d708dfad103df65f0c06 219 SUPERFAMILY SSF56281 2 211 1.83E-38 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_16730 c36abd3867e0d708dfad103df65f0c06 219 Gene3D G3DSA:3.60.15.10 1 213 1.5E-36 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_16730 c36abd3867e0d708dfad103df65f0c06 219 SMART SM00849 24 200 3.0E-27 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_12335 3288d10972fca0148fef9b6ebcad8467 60 Pfam PF08863 YolD-like protein 1 59 2.8E-9 T 15-10-2018 IPR014962 YolD-like protein C2I28_17030 ecafbc0cc6a766e0c4aa335bce79acc8 125 SUPERFAMILY SSF160631 54 124 1.57E-6 T 15-10-2018 C2I28_05870 2044823ccc2b434ac4a4f39174263d94 260 Gene3D G3DSA:3.40.50.1820 23 260 2.0E-42 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_05870 2044823ccc2b434ac4a4f39174263d94 260 SUPERFAMILY SSF53474 12 258 7.36E-44 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_05870 2044823ccc2b434ac4a4f39174263d94 260 Pfam PF00326 Prolyl oligopeptidase family 69 258 1.3E-22 T 15-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 C2I28_05870 2044823ccc2b434ac4a4f39174263d94 260 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 101 131 - T 15-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 C2I28_26130 2dfef871e76dc2ae46760c9a2f0226e3 112 Pfam PF11196 Protein of unknown function (DUF2834) 28 111 2.8E-8 T 15-10-2018 IPR021362 Protein of unknown function DUF2834 C2I28_00020 2dfef871e76dc2ae46760c9a2f0226e3 112 Pfam PF11196 Protein of unknown function (DUF2834) 28 111 2.8E-8 T 15-10-2018 IPR021362 Protein of unknown function DUF2834 C2I28_20610 ca0a74c44ff80d63cd8d266745ec1bf2 179 SUPERFAMILY SSF52218 1 152 9.35E-37 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_20610 ca0a74c44ff80d63cd8d266745ec1bf2 179 Pfam PF03358 NADPH-dependent FMN reductase 1 135 1.1E-30 T 15-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 C2I28_20610 ca0a74c44ff80d63cd8d266745ec1bf2 179 Gene3D G3DSA:3.40.50.360 1 172 2.8E-43 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_17620 923ccf0e4ee424192eaeeeddf56d251f 403 Gene3D G3DSA:1.20.1250.20 5 386 1.1E-59 T 15-10-2018 C2I28_17620 923ccf0e4ee424192eaeeeddf56d251f 403 Pfam PF07690 Major Facilitator Superfamily 15 249 2.1E-36 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_17620 923ccf0e4ee424192eaeeeddf56d251f 403 SUPERFAMILY SSF103473 1 391 8.5E-65 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 Pfam PF00375 Sodium:dicarboxylate symporter family 18 412 1.3E-123 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 48 63 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 SUPERFAMILY SSF118215 18 414 3.53E-124 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 308 331 - T 15-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 Gene3D G3DSA:1.10.3860.10 7 432 5.6E-135 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 205 224 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 158 180 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 340 359 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 305 331 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 367 387 2.2E-44 T 15-10-2018 C2I28_21230 56c0bd60f34e92466d90a39b06c320e6 435 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 2.2E-44 T 15-10-2018 C2I28_16625 c4ee942b683134a04fcc7862dee293d7 319 Pfam PF00682 HMGL-like 121 241 1.1E-23 T 15-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I28_16625 c4ee942b683134a04fcc7862dee293d7 319 Gene3D G3DSA:3.20.20.70 4 302 2.3E-79 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_16625 c4ee942b683134a04fcc7862dee293d7 319 SUPERFAMILY SSF51569 4 250 1.14E-42 T 15-10-2018 C2I28_00185 1cc79ea75456ad81bb623249fcd2673f 209 Pfam PF14278 Transcriptional regulator C-terminal region 96 173 5.5E-16 T 15-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type C2I28_00185 1cc79ea75456ad81bb623249fcd2673f 209 SUPERFAMILY SSF46689 8 75 1.95E-15 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_00185 1cc79ea75456ad81bb623249fcd2673f 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.6E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_00185 1cc79ea75456ad81bb623249fcd2673f 209 Gene3D G3DSA:1.10.357.10 5 194 4.1E-47 T 15-10-2018 C2I28_20325 8eeb84600ef78a10e2a6e66cc0e1b38f 467 SUPERFAMILY SSF53383 28 447 8.12E-129 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_20325 8eeb84600ef78a10e2a6e66cc0e1b38f 467 Gene3D G3DSA:3.40.640.10 70 361 1.4E-81 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_20325 8eeb84600ef78a10e2a6e66cc0e1b38f 467 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 44 383 5.0E-78 T 15-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 C2I28_20325 8eeb84600ef78a10e2a6e66cc0e1b38f 467 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 26 448 1.6E-197 T 15-10-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 C2I28_20325 8eeb84600ef78a10e2a6e66cc0e1b38f 467 Gene3D G3DSA:3.90.1150.160 363 467 1.0E-30 T 15-10-2018 C2I28_25930 86a81e479f78a29a973770eafc896eaa 55 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 11 54 1.5E-16 T 15-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 C2I28_25930 86a81e479f78a29a973770eafc896eaa 55 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 4 54 2.4E-13 T 15-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 C2I28_25855 a63c8a245754499368d79bf4b3113261 396 Gene3D G3DSA:1.20.1250.20 11 388 1.1E-38 T 15-10-2018 C2I28_25855 a63c8a245754499368d79bf4b3113261 396 Pfam PF07690 Major Facilitator Superfamily 22 319 3.0E-27 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_25855 a63c8a245754499368d79bf4b3113261 396 SUPERFAMILY SSF103473 15 390 2.22E-46 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 SUPERFAMILY SSF55200 78 167 4.84E-33 T 15-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 Gene3D G3DSA:3.30.110.10 75 167 8.0E-38 T 15-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 ProSitePatterns PS00938 Initiation factor 3 signature. 54 67 - T 15-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 79 164 3.1E-38 T 15-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 SUPERFAMILY SSF54364 2 74 1.16E-29 T 15-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 166 29.938 T 15-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 165 7.5E-76 T 15-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 3 72 2.3E-32 T 15-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I28_05315 6a4b85ea8a398c925d5a83193ebce9fc 167 Gene3D G3DSA:3.10.20.80 1 74 6.5E-34 T 15-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 C2I28_11875 3e2220f2a7d656e0826bec213ece27af 40 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 15 38 3.7E-11 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_11875 3e2220f2a7d656e0826bec213ece27af 40 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 13 34 1.6E-8 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 SUPERFAMILY SSF103025 4 282 3.92E-100 T 15-10-2018 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 364 48.598 T 15-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 SUPERFAMILY SSF101790 275 364 2.94E-27 T 15-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 261 6.5E-95 T 15-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 PIRSF PIRSF006487 1 366 1.5E-104 T 15-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Gene3D G3DSA:2.40.30.110 282 364 1.3E-33 T 15-10-2018 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Gene3D G3DSA:3.30.1360.120 7 238 3.9E-92 T 15-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Gene3D G3DSA:3.30.70.1400 54 139 3.9E-92 T 15-10-2018 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Gene3D G3DSA:4.10.1250.10 240 280 2.2E-15 T 15-10-2018 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 358 8.1E-28 T 15-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 C2I28_03985 350d2e874cd44dd0a75ae2124e914db7 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 364 1.9E-150 T 15-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 C2I28_21090 a5cbf9915d07f4d6b97639dae7a3d476 99 TIGRFAM TIGR04104 cxxc_20_cxxc: cxxc_20_cxxc protein 3 92 7.1E-23 T 15-10-2018 IPR026369 CxxC-20-CxxC protein C2I28_26995 4503bda294ded8db00c9e1f23b052c57 164 ProDom PD095338 YXII PLASMID 1 158 5.0E-63 T 15-10-2018 IPR020323 Protein of unknown function DUF2716 C2I28_26995 4503bda294ded8db00c9e1f23b052c57 164 Pfam PF10898 Protein of unknown function (DUF2716) 7 146 7.0E-53 T 15-10-2018 IPR020323 Protein of unknown function DUF2716 C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 SUPERFAMILY SSF54001 255 379 1.72E-34 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 SMART SM00257 199 242 3.8E-19 T 15-10-2018 IPR018392 LysM domain C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 Gene3D G3DSA:3.90.1720.10 252 380 3.3E-39 T 15-10-2018 C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 Pfam PF00877 NlpC/P60 family 273 376 1.8E-26 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 SUPERFAMILY SSF54106 198 241 6.02E-12 T 15-10-2018 C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 Gene3D G3DSA:3.10.350.10 195 247 1.9E-19 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_22970 c1644d7a80a6f24943248f822163fcf8 380 Pfam PF01476 LysM domain 200 241 5.5E-16 T 15-10-2018 IPR018392 LysM domain C2I28_17660 3cc6ac90372e85604734f8c06334e460 89 Gene3D G3DSA:3.40.50.12740 3 88 1.0E-5 T 15-10-2018 C2I28_17660 3cc6ac90372e85604734f8c06334e460 89 SUPERFAMILY SSF46689 1 88 2.51E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_17660 3cc6ac90372e85604734f8c06334e460 89 Pfam PF08765 Mor transcription activator family 9 88 9.3E-7 T 15-10-2018 IPR014875 Mor transcription activator C2I28_13650 b3b0218234299d81e7d948a65c78c340 152 Pfam PF04892 VanZ like family 29 141 2.2E-15 T 15-10-2018 IPR006976 VanZ-like C2I28_18765 820122ddb7db2598012555ef7f030361 187 SUPERFAMILY SSF53335 5 162 3.86E-21 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_18765 820122ddb7db2598012555ef7f030361 187 Gene3D G3DSA:3.40.50.150 14 170 6.1E-18 T 15-10-2018 C2I28_18765 820122ddb7db2598012555ef7f030361 187 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 110 2.5E-8 T 15-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm C2I28_01235 0c2c958b1175f8de0064551137737abf 413 SUPERFAMILY SSF53850 36 406 1.33E-84 T 15-10-2018 C2I28_01235 0c2c958b1175f8de0064551137737abf 413 Gene3D G3DSA:3.40.190.10 25 410 1.0E-87 T 15-10-2018 C2I28_01235 0c2c958b1175f8de0064551137737abf 413 Pfam PF13416 Bacterial extracellular solute-binding protein 56 351 1.9E-42 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_13475 039518281f710a4d84fa030190b05a1e 275 Pfam PF00583 Acetyltransferase (GNAT) family 27 122 1.9E-6 T 15-10-2018 IPR000182 GNAT domain C2I28_13475 039518281f710a4d84fa030190b05a1e 275 Gene3D G3DSA:3.40.630.30 5 128 2.2E-12 T 15-10-2018 C2I28_13475 039518281f710a4d84fa030190b05a1e 275 SUPERFAMILY SSF55729 2 126 4.8E-14 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_20785 5cc83ae08b0bb6ab2b906f45977aa456 456 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 443 2.9E-201 T 15-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 C2I28_20785 5cc83ae08b0bb6ab2b906f45977aa456 456 PIRSF PIRSF018788 1 456 9.7E-210 T 15-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 C2I28_20785 5cc83ae08b0bb6ab2b906f45977aa456 456 Gene3D G3DSA:3.20.20.70 142 453 7.8E-142 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_20785 5cc83ae08b0bb6ab2b906f45977aa456 456 Gene3D G3DSA:2.30.170.30 1 54 2.5E-22 T 15-10-2018 C2I28_20785 5cc83ae08b0bb6ab2b906f45977aa456 456 Gene3D G3DSA:1.10.220.70 55 141 2.7E-28 T 15-10-2018 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 15-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 TIGRFAM TIGR03356 BGL: beta-galactosidase 4 457 2.0E-146 T 15-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 7.5E-20 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 7.5E-20 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 434 446 7.5E-20 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 7.5E-20 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 7.5E-20 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 Gene3D G3DSA:3.20.20.80 1 468 1.3E-176 T 15-10-2018 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 Pfam PF00232 Glycosyl hydrolase family 1 3 464 7.5E-171 T 15-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 15-10-2018 IPR018120 Glycoside hydrolase family 1, active site C2I28_16475 9a370e26c215ed2f8ce66f5aa2762fae 468 SUPERFAMILY SSF51445 2 464 4.98E-169 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SMART SM00448 406 527 1.1E-27 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SMART SM00448 107 220 5.7E-25 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SUPERFAMILY SSF52172 107 236 7.68E-30 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 235 394 1.0E-42 T 15-10-2018 IPR000160 GGDEF domain C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 390 1.2E-39 T 15-10-2018 IPR000160 GGDEF domain C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 Gene3D G3DSA:3.40.50.2300 402 535 9.3E-31 T 15-10-2018 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SUPERFAMILY SSF55073 239 394 7.53E-44 T 15-10-2018 IPR029787 Nucleotide cyclase C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SUPERFAMILY SSF47226 9 93 3.79E-5 T 15-10-2018 IPR036641 HPT domain superfamily GO:0000160 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 Gene3D G3DSA:3.40.50.2300 94 231 4.8E-28 T 15-10-2018 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SMART SM00267 223 395 1.3E-48 T 15-10-2018 IPR000160 GGDEF domain C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 Gene3D G3DSA:3.30.70.270 232 401 3.2E-48 T 15-10-2018 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 Pfam PF00072 Response regulator receiver domain 109 215 2.2E-21 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 Pfam PF00072 Response regulator receiver domain 409 527 7.0E-22 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12860 730ba02a737a595a0aeb70c26c150878 535 SUPERFAMILY SSF52172 404 532 5.12E-30 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_13625 2f050c9ca3f30a41a4fa5d5375549bec 116 Gene3D G3DSA:1.10.260.40 1 113 4.6E-24 T 15-10-2018 C2I28_13625 2f050c9ca3f30a41a4fa5d5375549bec 116 SUPERFAMILY SSF47406 77 109 5.23E-7 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_13625 2f050c9ca3f30a41a4fa5d5375549bec 116 SUPERFAMILY SSF47413 2 63 2.68E-15 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_13625 2f050c9ca3f30a41a4fa5d5375549bec 116 Pfam PF01381 Helix-turn-helix 6 61 1.6E-13 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_13625 2f050c9ca3f30a41a4fa5d5375549bec 116 SMART SM00530 5 61 1.3E-12 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_03610 4e301334faeb39e34ecd75542e35ee03 303 SUPERFAMILY SSF53474 50 298 1.32E-37 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_03610 4e301334faeb39e34ecd75542e35ee03 303 Gene3D G3DSA:3.40.50.1820 56 303 8.6E-40 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_03610 4e301334faeb39e34ecd75542e35ee03 303 Pfam PF12146 Serine aminopeptidase, S33 83 189 1.3E-11 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_09905 9457a5e449c6fabafd5b518249f9ab18 429 SUPERFAMILY SSF51905 3 249 8.64E-21 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_09905 9457a5e449c6fabafd5b518249f9ab18 429 SUPERFAMILY SSF51905 244 342 2.59E-5 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_09905 9457a5e449c6fabafd5b518249f9ab18 429 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 338 2.3E-120 T 15-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase C2I28_09905 9457a5e449c6fabafd5b518249f9ab18 429 Gene3D G3DSA:3.50.50.60 1 421 3.1E-121 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_21625 55ba4afa5ab8cc3763afe8729bf11011 264 SUPERFAMILY SSF52266 59 262 3.66E-38 T 15-10-2018 C2I28_21625 55ba4afa5ab8cc3763afe8729bf11011 264 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 65 253 2.5E-27 T 15-10-2018 IPR013830 SGNH hydrolase-type esterase domain C2I28_21625 55ba4afa5ab8cc3763afe8729bf11011 264 Gene3D G3DSA:3.40.50.1110 59 263 7.4E-40 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 1.1E-15 T 15-10-2018 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 1.1E-15 T 15-10-2018 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 1.1E-15 T 15-10-2018 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 PRINTS PR00173 Glutamate-aspartate symporter signature 192 211 1.1E-15 T 15-10-2018 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 PRINTS PR00173 Glutamate-aspartate symporter signature 9 29 1.1E-15 T 15-10-2018 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 1.1E-15 T 15-10-2018 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 SUPERFAMILY SSF118215 14 402 2.09E-83 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 Gene3D G3DSA:1.10.3860.10 3 407 2.5E-80 T 15-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 C2I28_19790 d93b6c9fe0429290fc2be3a3c8ba27ff 420 Pfam PF00375 Sodium:dicarboxylate symporter family 15 402 3.1E-96 T 15-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 C2I28_22320 3b4278f71675e13c5de53346d7290767 437 Gene3D G3DSA:3.30.465.10 349 437 6.2E-18 T 15-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 C2I28_22320 3b4278f71675e13c5de53346d7290767 437 Pfam PF03471 Transporter associated domain 356 431 6.6E-17 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_22320 3b4278f71675e13c5de53346d7290767 437 Pfam PF01595 Domain of unknown function DUF21 7 201 1.1E-48 T 15-10-2018 IPR002550 CNNM, transmembrane domain C2I28_22320 3b4278f71675e13c5de53346d7290767 437 SUPERFAMILY SSF54631 204 342 9.22E-29 T 15-10-2018 C2I28_22320 3b4278f71675e13c5de53346d7290767 437 SMART SM01091 355 432 5.5E-22 T 15-10-2018 IPR005170 Transporter-associated domain C2I28_22320 3b4278f71675e13c5de53346d7290767 437 Gene3D G3DSA:3.10.580.10 195 348 4.4E-49 T 15-10-2018 C2I28_22320 3b4278f71675e13c5de53346d7290767 437 SUPERFAMILY SSF56176 352 434 1.45E-16 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_22320 3b4278f71675e13c5de53346d7290767 437 Pfam PF00571 CBS domain 217 271 2.1E-6 T 15-10-2018 IPR000644 CBS domain C2I28_23675 cb5c299d6039adab1fc78515c6e3002e 351 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 335 5.3E-87 T 15-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 C2I28_23675 cb5c299d6039adab1fc78515c6e3002e 351 Gene3D G3DSA:3.20.20.70 1 349 1.2E-114 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_23675 cb5c299d6039adab1fc78515c6e3002e 351 SUPERFAMILY SSF51395 3 343 6.77E-107 T 15-10-2018 C2I28_05595 f612f05c510699fe9baa24fc85712210 159 SUPERFAMILY SSF55781 12 153 5.67E-45 T 15-10-2018 C2I28_05595 f612f05c510699fe9baa24fc85712210 159 Gene3D G3DSA:3.30.450.40 10 159 8.5E-66 T 15-10-2018 IPR029016 GAF-like domain superfamily C2I28_05595 f612f05c510699fe9baa24fc85712210 159 Pfam PF13185 GAF domain 48 153 3.2E-12 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_05595 f612f05c510699fe9baa24fc85712210 159 SMART SM00065 31 156 0.0033 T 15-10-2018 IPR003018 GAF domain GO:0005515 C2I28_05595 f612f05c510699fe9baa24fc85712210 159 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 15-10-2018 IPR000614 Free Met sulfoxide reductase conserved site C2I28_20010 845a15f6aa11ee94d7629d1f40769b03 130 SUPERFAMILY SSF52833 9 96 2.57E-20 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_20010 845a15f6aa11ee94d7629d1f40769b03 130 Gene3D G3DSA:3.40.30.10 8 101 5.0E-22 T 15-10-2018 C2I28_20010 845a15f6aa11ee94d7629d1f40769b03 130 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 9 88 1.9E-7 T 15-10-2018 C2I28_17350 801cd35d92bec9c436ad545464445b7a 444 Pfam PF03600 Citrate transporter 24 383 1.9E-53 T 15-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I28_17350 801cd35d92bec9c436ad545464445b7a 444 PRINTS PR00758 Arsenical pump membrane protein signature 227 252 3.6E-8 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17350 801cd35d92bec9c436ad545464445b7a 444 PRINTS PR00758 Arsenical pump membrane protein signature 287 311 3.6E-8 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17350 801cd35d92bec9c436ad545464445b7a 444 PRINTS PR00758 Arsenical pump membrane protein signature 110 134 3.6E-8 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17350 801cd35d92bec9c436ad545464445b7a 444 PRINTS PR00758 Arsenical pump membrane protein signature 379 404 3.6E-8 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_17270 ecf29f685f02816ca189ee824d1bc4ed 446 SUPERFAMILY SSF103473 14 426 1.28E-71 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_17270 ecf29f685f02816ca189ee824d1bc4ed 446 Pfam PF07690 Major Facilitator Superfamily 28 359 1.6E-46 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_17270 ecf29f685f02816ca189ee824d1bc4ed 446 Gene3D G3DSA:1.20.1250.20 13 212 5.1E-40 T 15-10-2018 C2I28_17270 ecf29f685f02816ca189ee824d1bc4ed 446 Gene3D G3DSA:1.20.1250.20 225 433 5.0E-22 T 15-10-2018 C2I28_13940 eb27de8a69f2803a7ebd4afbf3fc8dd0 152 SUPERFAMILY SSF55729 4 150 4.22E-28 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_13940 eb27de8a69f2803a7ebd4afbf3fc8dd0 152 Pfam PF00583 Acetyltransferase (GNAT) family 26 141 2.4E-18 T 15-10-2018 IPR000182 GNAT domain C2I28_13940 eb27de8a69f2803a7ebd4afbf3fc8dd0 152 Gene3D G3DSA:3.40.630.30 2 152 4.5E-41 T 15-10-2018 C2I28_25645 02c4544d10e1cf4759569a68b596c90b 127 Pfam PF13115 YtkA-like 26 106 2.1E-13 T 15-10-2018 IPR032693 YtkA-like domain C2I28_09810 c2428c5a8628f2ca660a80a11250d6f5 130 Pfam PF07179 SseB protein N-terminal domain 8 120 1.1E-15 T 15-10-2018 IPR009839 SseB protein N-terminal domain C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 Gene3D G3DSA:3.30.700.10 9 67 1.6E-7 T 15-10-2018 C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 PRINTS PR00813 Bacterial general secretion pathway protein G signature 44 62 1.7E-9 T 15-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 PRINTS PR00813 Bacterial general secretion pathway protein G signature 8 33 1.7E-9 T 15-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 PIRSF PIRSF029928 1 100 2.7E-32 T 15-10-2018 IPR016940 ComG operon protein C GO:0030420 C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 28 1.4E-7 T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 SUPERFAMILY SSF54523 9 84 7.06E-11 T 15-10-2018 C2I28_04025 4cdb4ca2b8210d6ebb79e9f01d65c650 103 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 28 1.8E-7 T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_17920 b8848cfe783e58cb0adebbcc13f1e816 503 Pfam PF01593 Flavin containing amine oxidoreductase 12 489 3.4E-31 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_17920 b8848cfe783e58cb0adebbcc13f1e816 503 Gene3D G3DSA:3.50.50.60 194 329 1.2E-23 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17920 b8848cfe783e58cb0adebbcc13f1e816 503 Gene3D G3DSA:3.50.50.60 1 114 3.2E-28 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17920 b8848cfe783e58cb0adebbcc13f1e816 503 SUPERFAMILY SSF51905 1 492 9.79E-71 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_17920 b8848cfe783e58cb0adebbcc13f1e816 503 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 494 3.9E-133 T 15-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 C2I28_08805 608809e732b4bd5a9ebf3fc55cc4543b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 15-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08805 608809e732b4bd5a9ebf3fc55cc4543b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.611 T 15-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08805 608809e732b4bd5a9ebf3fc55cc4543b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 5.8E-24 T 15-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08805 608809e732b4bd5a9ebf3fc55cc4543b 37 Pfam PF00444 Ribosomal protein L36 1 37 3.2E-19 T 15-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08805 608809e732b4bd5a9ebf3fc55cc4543b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 15-10-2018 C2I28_08805 608809e732b4bd5a9ebf3fc55cc4543b 37 SUPERFAMILY SSF57840 1 37 6.28E-17 T 15-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_14810 dc5ce642bc9075bbdcf64106c779b0b5 89 Gene3D G3DSA:1.10.220.80 12 89 1.7E-30 T 15-10-2018 IPR023324 BH2638-like superfamily C2I28_14810 dc5ce642bc9075bbdcf64106c779b0b5 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 3 89 2.0E-26 T 15-10-2018 IPR007920 Protein of unknown function UPF0223 C2I28_14810 dc5ce642bc9075bbdcf64106c779b0b5 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 86 3.1E-39 T 15-10-2018 IPR007920 Protein of unknown function UPF0223 C2I28_14810 dc5ce642bc9075bbdcf64106c779b0b5 89 SUPERFAMILY SSF158504 4 85 1.44E-33 T 15-10-2018 IPR023324 BH2638-like superfamily C2I28_14810 dc5ce642bc9075bbdcf64106c779b0b5 89 Hamap MF_01041 UPF0223 protein . 1 89 25.424 T 15-10-2018 IPR007920 Protein of unknown function UPF0223 C2I28_14810 dc5ce642bc9075bbdcf64106c779b0b5 89 PIRSF PIRSF037260 1 89 1.8E-38 T 15-10-2018 IPR007920 Protein of unknown function UPF0223 C2I28_05915 f7441cb8959078e589a5fcecab4f5460 75 SMART SM01234 2 69 5.5E-44 T 15-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I28_05915 f7441cb8959078e589a5fcecab4f5460 75 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 69 4.0E-19 T 15-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I28_05915 f7441cb8959078e589a5fcecab4f5460 75 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 73 1.5E-32 T 15-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I28_05915 f7441cb8959078e589a5fcecab4f5460 75 Pfam PF01809 Haemolytic domain 4 69 9.9E-30 T 15-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I28_05915 f7441cb8959078e589a5fcecab4f5460 75 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 24.331 T 15-10-2018 IPR002696 Putative membrane protein insertion efficiency factor C2I28_19880 1ee246255c9944a9124002e6b707dc76 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 266 4.7E-60 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_19880 1ee246255c9944a9124002e6b707dc76 267 SUPERFAMILY SSF52096 11 266 7.47E-78 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_19880 1ee246255c9944a9124002e6b707dc76 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 15-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I28_19880 1ee246255c9944a9124002e6b707dc76 267 Gene3D G3DSA:1.10.12.10 210 267 3.3E-21 T 15-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I28_19880 1ee246255c9944a9124002e6b707dc76 267 Gene3D G3DSA:3.90.226.10 2 208 1.3E-62 T 15-10-2018 C2I28_09470 8be704ca55f9c0118822288664b976f0 192 Gene3D G3DSA:3.40.50.170 1 192 1.5E-76 T 15-10-2018 C2I28_09470 8be704ca55f9c0118822288664b976f0 192 Pfam PF00551 Formyl transferase 3 182 7.8E-62 T 15-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_09470 8be704ca55f9c0118822288664b976f0 192 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 189 7.0E-74 T 15-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 C2I28_09470 8be704ca55f9c0118822288664b976f0 192 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 15-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_09470 8be704ca55f9c0118822288664b976f0 192 SUPERFAMILY SSF53328 3 188 1.13E-61 T 15-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 C2I28_09470 8be704ca55f9c0118822288664b976f0 192 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 31.771 T 15-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 C2I28_19650 87d1cc6956189621576b82fbd5d703f7 783 Pfam PF05547 Immune inhibitor A peptidase M6 142 779 1.1E-267 T 15-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I28_19650 87d1cc6956189621576b82fbd5d703f7 783 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 177 477 5.3E-92 T 15-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 C2I28_19650 87d1cc6956189621576b82fbd5d703f7 783 SUPERFAMILY SSF55486 257 416 3.54E-17 T 15-10-2018 C2I28_19650 87d1cc6956189621576b82fbd5d703f7 783 PIRSF PIRSF007519 12 783 2.2E-291 T 15-10-2018 IPR012300 Peptidase M6, InhA C2I28_12620 9441f207cde0fda31dd87abbc05028f2 336 SUPERFAMILY SSF53850 38 326 5.93E-39 T 15-10-2018 C2I28_12620 9441f207cde0fda31dd87abbc05028f2 336 Pfam PF09084 NMT1/THI5 like 46 260 1.3E-72 T 15-10-2018 IPR015168 SsuA/THI5-like C2I28_12620 9441f207cde0fda31dd87abbc05028f2 336 Gene3D G3DSA:3.40.190.10 39 313 3.8E-94 T 15-10-2018 C2I28_12620 9441f207cde0fda31dd87abbc05028f2 336 Gene3D G3DSA:3.40.190.10 119 221 3.8E-94 T 15-10-2018 C2I28_23800 7b6b3c63443bad20b541021eda81f175 168 Pfam PF13798 Protein of unknown function with PCYCGC motif 11 166 3.0E-62 T 15-10-2018 IPR025673 Protein of unknown function with PCYCGC motif C2I28_15275 f0dfcb13a7f50928ec8195c6878c9be0 436 Pfam PF00860 Permease family 5 383 4.0E-120 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_15275 f0dfcb13a7f50928ec8195c6878c9be0 436 TIGRFAM TIGR03173 pbuX: xanthine permease 9 415 1.0E-167 T 15-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 C2I28_15275 f0dfcb13a7f50928ec8195c6878c9be0 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 330 350 - T 15-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I28_15275 f0dfcb13a7f50928ec8195c6878c9be0 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 5 413 3.3E-142 T 15-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I28_12225 8fa59575a8ae7b6cc242354ade670af0 351 Pfam PF17118 Domain of unknown function (DUF5105) 162 345 3.7E-58 T 15-10-2018 IPR031343 Domain of unknown function DUF5105 C2I28_12225 8fa59575a8ae7b6cc242354ade670af0 351 Gene3D G3DSA:2.60.40.1240 30 166 2.6E-9 T 15-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily C2I28_05965 e8c237224b459fdf90f8a8f9f9fd8c46 52 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 8.3E-16 T 15-10-2018 IPR011437 Domain of unknown function DUF1540 C2I28_13970 bf15a781ea823c445213b2e0f1eecbb4 239 Pfam PF04474 Protein of unknown function (DUF554) 4 231 1.8E-71 T 15-10-2018 IPR007563 Protein of unknown function DUF554 C2I28_13545 8e0d8967275dd4d76655ac8441ef64b5 253 Gene3D G3DSA:3.40.50.1820 2 240 1.9E-27 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_13545 8e0d8967275dd4d76655ac8441ef64b5 253 SUPERFAMILY SSF53474 4 240 8.76E-29 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 10 399 1.1E-165 T 15-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 PIRSF PIRSF000521 1 163 3.1E-8 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 PIRSF PIRSF000521 179 401 2.3E-33 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 Gene3D G3DSA:3.90.1150.10 27 389 3.5E-153 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 Pfam PF00202 Aminotransferase class-III 20 398 2.4E-134 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 227 264 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 Hamap MF_01689 Ornithine aminotransferase [rocD]. 8 400 66.265 T 15-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 SUPERFAMILY SSF53383 6 400 2.31E-126 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_11475 feeacb86ee56a8aa5b82315726754c61 401 Gene3D G3DSA:3.40.640.10 62 310 3.5E-153 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_16310 e20a93e0844086438a45b5149b231126 279 Pfam PF12146 Serine aminopeptidase, S33 23 265 9.1E-19 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_16310 e20a93e0844086438a45b5149b231126 279 SUPERFAMILY SSF53474 3 275 5.62E-59 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_16310 e20a93e0844086438a45b5149b231126 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.4E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16310 e20a93e0844086438a45b5149b231126 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 224 238 2.4E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16310 e20a93e0844086438a45b5149b231126 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.4E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_16310 e20a93e0844086438a45b5149b231126 279 Gene3D G3DSA:3.40.50.1820 1 277 1.7E-63 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_18355 71e7ef31ca2c7b16acf4a43f404be0ff 134 Pfam PF03788 LrgA family 18 108 1.1E-27 T 15-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I28_13465 5914b665b9c9f59af440903716807817 451 Pfam PF02040 Arsenical pump membrane protein 7 446 5.8E-68 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_13465 5914b665b9c9f59af440903716807817 451 PRINTS PR00758 Arsenical pump membrane protein signature 148 172 1.4E-24 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_13465 5914b665b9c9f59af440903716807817 451 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 1.4E-24 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_13465 5914b665b9c9f59af440903716807817 451 PRINTS PR00758 Arsenical pump membrane protein signature 418 442 1.4E-24 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_13465 5914b665b9c9f59af440903716807817 451 PRINTS PR00758 Arsenical pump membrane protein signature 385 410 1.4E-24 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 SMART SM00922 140 238 4.4E-27 T 15-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 SUPERFAMILY SSF54826 1 124 8.61E-25 T 15-10-2018 C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 SUPERFAMILY SSF51604 117 349 2.36E-64 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 Gene3D G3DSA:3.30.390.10 6 115 2.7E-105 T 15-10-2018 IPR029017 Enolase-like, N-terminal C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 5 124 6.7E-16 T 15-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 Gene3D G3DSA:3.20.20.120 116 349 2.7E-105 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_10490 db611fd89579bf8b1ff6b997775bf6bf 357 Pfam PF13378 Enolase C-terminal domain-like 143 349 1.2E-49 T 15-10-2018 IPR029065 Enolase C-terminal domain-like C2I28_08640 101cb7cf0e5b783ca66893d5d4bc4298 200 Pfam PF05175 Methyltransferase small domain 29 195 4.9E-51 T 15-10-2018 IPR007848 Methyltransferase small domain GO:0008168 C2I28_08640 101cb7cf0e5b783ca66893d5d4bc4298 200 Gene3D G3DSA:3.40.50.150 6 200 2.6E-47 T 15-10-2018 C2I28_08640 101cb7cf0e5b783ca66893d5d4bc4298 200 SUPERFAMILY SSF53335 16 199 2.22E-37 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_25000 0ad1c73dc6a7916429e81afec9d06966 170 Pfam PF07301 Protein of unknown function (DUF1453) 8 160 5.0E-30 T 15-10-2018 IPR009916 Protein of unknown function DUF1453 C2I28_09180 74990bea39b90655f5582bb886f46199 161 SUPERFAMILY SSF55874 35 136 3.41E-15 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09180 74990bea39b90655f5582bb886f46199 161 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 158 3.0E-73 T 15-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I28_09180 74990bea39b90655f5582bb886f46199 161 Gene3D G3DSA:3.30.565.10 4 156 1.9E-24 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_09180 74990bea39b90655f5582bb886f46199 161 Pfam PF13581 Histidine kinase-like ATPase domain 12 141 5.7E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_09180 74990bea39b90655f5582bb886f46199 161 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 157 40.895 T 15-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 C2I28_07290 f55e5e13b1db99021059cd9c0f7f4b74 340 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 7 327 6.4E-129 T 15-10-2018 IPR014225 Sporulation stage II, protein D firmicutes C2I28_07290 f55e5e13b1db99021059cd9c0f7f4b74 340 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 69 327 4.0E-77 T 15-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 C2I28_07290 f55e5e13b1db99021059cd9c0f7f4b74 340 Pfam PF08486 Stage II sporulation protein 64 168 1.1E-26 T 15-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal C2I28_09645 598aa4cf7f9edcb6f24d8a2c7550b58a 451 Pfam PF00324 Amino acid permease 16 436 8.3E-93 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_09645 598aa4cf7f9edcb6f24d8a2c7550b58a 451 Gene3D G3DSA:1.20.1740.10 9 451 3.6E-60 T 15-10-2018 C2I28_09645 598aa4cf7f9edcb6f24d8a2c7550b58a 451 PIRSF PIRSF006060 1 451 6.3E-74 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_09645 598aa4cf7f9edcb6f24d8a2c7550b58a 451 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_08025 6a6f75b4ad30494beb0948c36ba69201 71 Gene3D G3DSA:3.10.290.10 1 70 5.7E-24 T 15-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 C2I28_08025 6a6f75b4ad30494beb0948c36ba69201 71 SUPERFAMILY SSF55174 3 69 2.16E-18 T 15-10-2018 C2I28_08025 6a6f75b4ad30494beb0948c36ba69201 71 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 62 1.7E-31 T 15-10-2018 IPR014330 RNA-binding S4-related,YaaA C2I28_08025 6a6f75b4ad30494beb0948c36ba69201 71 Pfam PF13275 S4 domain 5 67 2.0E-27 T 15-10-2018 C2I28_16350 3dc833ea71f2faf269828c7933c4fc74 232 Pfam PF01522 Polysaccharide deacetylase 38 139 5.9E-26 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_16350 3dc833ea71f2faf269828c7933c4fc74 232 Gene3D G3DSA:3.20.20.370 23 232 2.1E-58 T 15-10-2018 C2I28_16350 3dc833ea71f2faf269828c7933c4fc74 232 SUPERFAMILY SSF88713 38 230 6.18E-54 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_07950 2df67f83b4c94966b9f11884858795b6 297 SUPERFAMILY SSF82861 28 118 3.66E-15 T 15-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 C2I28_07950 2df67f83b4c94966b9f11884858795b6 297 Gene3D G3DSA:2.30.30.60 135 183 5.8E-22 T 15-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily C2I28_07950 2df67f83b4c94966b9f11884858795b6 297 Pfam PF00924 Mechanosensitive ion channel 76 273 6.9E-48 T 15-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 C2I28_07950 2df67f83b4c94966b9f11884858795b6 297 SUPERFAMILY SSF82689 186 283 8.89E-16 T 15-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 C2I28_07950 2df67f83b4c94966b9f11884858795b6 297 Gene3D G3DSA:3.30.70.100 185 272 3.4E-21 T 15-10-2018 C2I28_07950 2df67f83b4c94966b9f11884858795b6 297 SUPERFAMILY SSF50182 119 180 1.24E-15 T 15-10-2018 IPR010920 LSM domain superfamily C2I28_25840 86944a88e1b12a112d1f1f207bb324e8 302 Pfam PF00892 EamA-like transporter family 8 134 7.8E-25 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_25840 86944a88e1b12a112d1f1f207bb324e8 302 Pfam PF00892 EamA-like transporter family 149 284 1.3E-20 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_25840 86944a88e1b12a112d1f1f207bb324e8 302 SUPERFAMILY SSF103481 183 288 1.26E-14 T 15-10-2018 C2I28_25840 86944a88e1b12a112d1f1f207bb324e8 302 SUPERFAMILY SSF103481 37 135 2.35E-17 T 15-10-2018 C2I28_10675 aeb2ba370ff554f8d129def0c7fe1b2c 317 SUPERFAMILY SSF53335 158 268 6.27E-18 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_10675 aeb2ba370ff554f8d129def0c7fe1b2c 317 Gene3D G3DSA:3.40.50.150 155 317 2.3E-19 T 15-10-2018 C2I28_10675 aeb2ba370ff554f8d129def0c7fe1b2c 317 Pfam PF01170 Putative RNA methylase family UPF0020 158 260 6.0E-8 T 15-10-2018 IPR000241 Putative RNA methylase domain C2I28_13180 f86265aa468f92f7b32dd659b95955a0 163 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 15-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 C2I28_13180 f86265aa468f92f7b32dd659b95955a0 163 PRINTS PR00502 NUDIX hydrolase family signature 35 49 2.7E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_13180 f86265aa468f92f7b32dd659b95955a0 163 PRINTS PR00502 NUDIX hydrolase family signature 49 64 2.7E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_13180 f86265aa468f92f7b32dd659b95955a0 163 Pfam PF00293 NUDIX domain 5 130 2.1E-15 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_13180 f86265aa468f92f7b32dd659b95955a0 163 Gene3D G3DSA:3.90.79.10 2 143 6.5E-24 T 15-10-2018 C2I28_13180 f86265aa468f92f7b32dd659b95955a0 163 SUPERFAMILY SSF55811 9 140 2.71E-26 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_11910 98a7b2097590eefccd88e320610d1fa7 170 Hamap MF_01444 Putative phosphoesterase . 1 168 39.203 T 15-10-2018 IPR022932 Putative phosphoesterase YjcG C2I28_11910 98a7b2097590eefccd88e320610d1fa7 170 SUPERFAMILY SSF55144 1 169 1.73E-33 T 15-10-2018 IPR009097 Cyclic phosphodiesterase C2I28_11910 98a7b2097590eefccd88e320610d1fa7 170 Gene3D G3DSA:3.90.1140.10 2 170 5.1E-45 T 15-10-2018 C2I28_11910 98a7b2097590eefccd88e320610d1fa7 170 Pfam PF13563 2'-5' RNA ligase superfamily 11 153 1.9E-24 T 15-10-2018 C2I28_18995 cd750cc96cf5318b09bc6c448e36d153 160 Pfam PF00717 Peptidase S24-like 34 78 3.9E-6 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_18995 cd750cc96cf5318b09bc6c448e36d153 160 SUPERFAMILY SSF51306 34 99 8.11E-7 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_18995 cd750cc96cf5318b09bc6c448e36d153 160 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 34 144 5.6E-19 T 15-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 C2I28_09490 ae8d45cc85671f2745e01ffe5864cb8c 582 SUPERFAMILY SSF51556 82 332 6.81E-7 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_09490 ae8d45cc85671f2745e01ffe5864cb8c 582 Gene3D G3DSA:2.30.40.10 21 362 4.3E-78 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_09490 ae8d45cc85671f2745e01ffe5864cb8c 582 Gene3D G3DSA:3.20.20.140 83 326 4.3E-78 T 15-10-2018 C2I28_09490 ae8d45cc85671f2745e01ffe5864cb8c 582 SUPERFAMILY SSF51338 21 370 2.47E-13 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_09490 ae8d45cc85671f2745e01ffe5864cb8c 582 Pfam PF01979 Amidohydrolase family 79 361 1.2E-12 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_09490 ae8d45cc85671f2745e01ffe5864cb8c 582 Pfam PF13382 Adenine deaminase C-terminal domain 418 573 2.4E-36 T 15-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 C2I28_15685 f2778b1d0694879418a7904afa7c4c77 121 Pfam PF01638 HxlR-like helix-turn-helix 19 107 7.9E-40 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_15685 f2778b1d0694879418a7904afa7c4c77 121 Gene3D G3DSA:1.10.10.10 4 115 2.2E-39 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_15685 f2778b1d0694879418a7904afa7c4c77 121 SUPERFAMILY SSF46785 8 113 1.28E-34 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21450 13be1ccd4d6e2aa49b2caf39d7485b42 197 Pfam PF09335 SNARE associated Golgi protein 29 154 1.9E-25 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_07350 f44520d552163a8cd6ac48e247aaff01 123 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 121 2.0E-51 T 15-10-2018 C2I28_07350 f44520d552163a8cd6ac48e247aaff01 123 Pfam PF03899 ATP synthase I chain 10 105 1.3E-17 T 15-10-2018 IPR005598 ATP synthase protein I C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 SUPERFAMILY SSF52440 4 94 3.88E-26 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 Gene3D G3DSA:3.40.50.20 2 116 4.2E-45 T 15-10-2018 C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 Gene3D G3DSA:3.30.470.20 186 375 7.7E-78 T 15-10-2018 C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 Gene3D G3DSA:3.30.1490.20 117 185 9.0E-26 T 15-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 365 2.4E-126 T 15-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 360 41.231 T 15-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 SUPERFAMILY SSF51246 309 375 5.65E-16 T 15-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 Pfam PF02222 ATP-grasp domain 116 285 3.0E-60 T 15-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type C2I28_09430 f66eca15f339f94421d50b53bf596ad6 381 SUPERFAMILY SSF56059 107 305 4.07E-66 T 15-10-2018 C2I28_00615 ddeb5dd199e8ddf683b0f4bfd0f34c2e 221 SUPERFAMILY SSF102198 4 218 3.66E-47 T 15-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I28_00615 ddeb5dd199e8ddf683b0f4bfd0f34c2e 221 Gene3D G3DSA:3.50.30.50 1 218 2.5E-51 T 15-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I28_00615 ddeb5dd199e8ddf683b0f4bfd0f34c2e 221 Pfam PF04199 Putative cyclase 7 161 1.9E-21 T 15-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I28_22695 d38c06fda5d5debd94e07fbd16ed35bf 162 Pfam PF14526 Integron-associated effector binding protein 11 162 1.5E-22 T 15-10-2018 IPR029441 Integron-associated effector binding protein C2I28_22695 d38c06fda5d5debd94e07fbd16ed35bf 162 SUPERFAMILY SSF55136 10 162 8.63E-19 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_22695 d38c06fda5d5debd94e07fbd16ed35bf 162 Gene3D G3DSA:3.20.80.10 5 162 4.5E-34 T 15-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily C2I28_22695 d38c06fda5d5debd94e07fbd16ed35bf 162 SMART SM00871 7 162 2.6E-18 T 15-10-2018 IPR010499 Bacterial transcription activator, effector binding C2I28_07770 fe267be4c2bb019727db13d1718119fa 602 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 417 537 4.8E-28 T 15-10-2018 IPR025299 CstA, C-terminal domain C2I28_07770 fe267be4c2bb019727db13d1718119fa 602 Pfam PF02554 Carbon starvation protein CstA 1 368 3.4E-146 T 15-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 C2I28_07515 f1734c887b679fac24c058140c2b9112 317 SUPERFAMILY SSF51658 83 266 2.65E-17 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_07515 f1734c887b679fac24c058140c2b9112 317 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 303 38.994 T 15-10-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 C2I28_07515 f1734c887b679fac24c058140c2b9112 317 Pfam PF03851 UV-endonuclease UvdE 5 273 2.0E-114 T 15-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I28_07515 f1734c887b679fac24c058140c2b9112 317 Gene3D G3DSA:3.20.20.150 2 307 1.3E-97 T 15-10-2018 C2I28_07515 f1734c887b679fac24c058140c2b9112 317 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 301 1.6E-109 T 15-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 C2I28_05440 3f269cc38d8c420f52050ce8bf6f0bdc 200 SUPERFAMILY SSF46785 5 80 3.9E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_05440 3f269cc38d8c420f52050ce8bf6f0bdc 200 Gene3D G3DSA:1.10.10.10 7 131 3.8E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05440 3f269cc38d8c420f52050ce8bf6f0bdc 200 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 4.9E-18 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_05440 3f269cc38d8c420f52050ce8bf6f0bdc 200 SMART SM00345 12 71 9.9E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_05440 3f269cc38d8c420f52050ce8bf6f0bdc 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 3.6E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_05440 3f269cc38d8c420f52050ce8bf6f0bdc 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 3.6E-9 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_17780 4ba4def2b03c569b9f75ee5f558c3308 104 Pfam PF00085 Thioredoxin 5 100 3.0E-15 T 15-10-2018 IPR013766 Thioredoxin domain GO:0045454 C2I28_17780 4ba4def2b03c569b9f75ee5f558c3308 104 SUPERFAMILY SSF52833 4 102 6.8E-21 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_17780 4ba4def2b03c569b9f75ee5f558c3308 104 Gene3D G3DSA:3.40.30.10 1 103 1.8E-20 T 15-10-2018 C2I28_21100 d842458f5d38320bd88ab273f73c9cee 148 SMART SM00422 2 72 2.2E-24 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_21100 d842458f5d38320bd88ab273f73c9cee 148 Pfam PF13411 MerR HTH family regulatory protein 2 70 4.0E-18 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_21100 d842458f5d38320bd88ab273f73c9cee 148 SUPERFAMILY SSF46955 2 103 2.05E-20 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_21100 d842458f5d38320bd88ab273f73c9cee 148 Gene3D G3DSA:1.10.1660.10 1 134 6.6E-26 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 15-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 1.8E-68 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 1.8E-68 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 1.8E-68 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 1.8E-68 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 1.8E-68 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 1.8E-68 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 Pfam PF14698 Argininosuccinate lyase C-terminal 364 432 6.9E-25 T 15-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05495 fad801ae493466ad7c961737eab98285 462 SUPERFAMILY SSF48557 4 456 3.14E-148 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 6.7E-29 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 6.7E-29 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 6.7E-29 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_05495 fad801ae493466ad7c961737eab98285 462 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 6.7E-29 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_05495 fad801ae493466ad7c961737eab98285 462 Pfam PF00206 Lyase 7 301 6.0E-76 T 15-10-2018 IPR022761 Fumarate lyase, N-terminal C2I28_05495 fad801ae493466ad7c961737eab98285 462 Gene3D G3DSA:1.10.275.10 26 230 2.5E-194 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_05495 fad801ae493466ad7c961737eab98285 462 Gene3D G3DSA:1.20.200.10 120 449 2.5E-194 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 44.032 T 15-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_05495 fad801ae493466ad7c961737eab98285 462 Gene3D G3DSA:1.10.40.30 361 433 2.5E-194 T 15-10-2018 C2I28_05495 fad801ae493466ad7c961737eab98285 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 456 4.2E-205 T 15-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 Gene3D G3DSA:3.40.50.300 211 400 4.0E-43 T 15-10-2018 C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 SUPERFAMILY SSF52540 70 353 1.49E-60 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 Gene3D G3DSA:3.40.50.300 2 205 6.4E-64 T 15-10-2018 C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 Pfam PF00270 DEAD/DEAH box helicase 25 189 6.5E-40 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 SMART SM00490 252 333 3.7E-28 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 SMART SM00487 20 217 4.0E-52 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_09795 2a5cf42a7479dc414e282c488afbc27b 401 Pfam PF00271 Helicase conserved C-terminal domain 225 333 5.7E-27 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_09095 61dbeba7d1747068bee577c59368c9af 310 Gene3D G3DSA:3.10.520.20 1 309 2.4E-68 T 15-10-2018 C2I28_09095 61dbeba7d1747068bee577c59368c9af 310 Pfam PF02424 ApbE family 14 280 2.1E-56 T 15-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 C2I28_09095 61dbeba7d1747068bee577c59368c9af 310 PIRSF PIRSF006268 1 307 3.0E-56 T 15-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 C2I28_09095 61dbeba7d1747068bee577c59368c9af 310 SUPERFAMILY SSF143631 6 302 3.58E-65 T 15-10-2018 IPR003374 ApbE-like superfamily C2I28_01160 402a46d1a10030a4c5dcea6f81a7a312 192 Pfam PF05076 Suppressor of fused protein (SUFU) 36 189 7.2E-22 T 15-10-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 C2I28_01160 402a46d1a10030a4c5dcea6f81a7a312 192 ProDom PD105609 PLASMID YQCF RSP1132 11 191 6.0E-31 T 15-10-2018 C2I28_17100 e09acacc1c8f010c81f3da5c24da23b7 136 Gene3D G3DSA:3.40.630.30 3 123 3.6E-16 T 15-10-2018 C2I28_17100 e09acacc1c8f010c81f3da5c24da23b7 136 Pfam PF13508 Acetyltransferase (GNAT) domain 39 115 3.6E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_17100 e09acacc1c8f010c81f3da5c24da23b7 136 SUPERFAMILY SSF55729 22 124 5.58E-17 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 Gene3D G3DSA:3.40.50.720 1 165 4.9E-50 T 15-10-2018 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 19 5.0E-24 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 58 87 5.0E-24 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 155 183 5.0E-24 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 230 257 5.0E-24 T 15-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 152 7.6E-42 T 15-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 Gene3D G3DSA:1.10.1040.10 166 296 6.1E-50 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 297 3.9E-149 T 15-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 SUPERFAMILY SSF48179 164 296 6.24E-41 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 SUPERFAMILY SSF51735 1 152 4.98E-45 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 SMART SM01350 166 297 1.9E-6 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_24245 321939a8d6bd4f7903e8736561be650a 297 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 166 274 2.8E-24 T 15-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 C2I28_01450 939b2e2dd2ebfdea7193d2aef78e491e 139 Pfam PF04138 GtrA-like protein 7 129 1.9E-20 T 15-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 C2I28_14930 30bb05000c5a3bf322d0392ee9329744 119 SUPERFAMILY SSF160755 1 114 2.09E-39 T 15-10-2018 IPR036491 YugN-like superfamily C2I28_14930 30bb05000c5a3bf322d0392ee9329744 119 Gene3D G3DSA:3.30.310.100 1 119 3.8E-44 T 15-10-2018 IPR036491 YugN-like superfamily C2I28_14930 30bb05000c5a3bf322d0392ee9329744 119 Pfam PF08868 YugN-like family 11 101 5.5E-13 T 15-10-2018 IPR014967 Uncharacterised protein family, YugN-like C2I28_00735 bce553b5c16f3204405dcd4a3138c7a4 304 Pfam PF01619 Proline dehydrogenase 45 294 1.5E-31 T 15-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 C2I28_00735 bce553b5c16f3204405dcd4a3138c7a4 304 Gene3D G3DSA:3.20.20.530 19 303 2.8E-93 T 15-10-2018 C2I28_00735 bce553b5c16f3204405dcd4a3138c7a4 304 SUPERFAMILY SSF51730 38 301 1.22E-73 T 15-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I28_00735 bce553b5c16f3204405dcd4a3138c7a4 304 PIRSF PIRSF000196 2 304 1.1E-130 T 15-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 C2I28_12315 a5537cf5c741df50eebb40a64233c3b9 478 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_12315 a5537cf5c741df50eebb40a64233c3b9 478 PIRSF PIRSF006060 1 475 9.2E-88 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_12315 a5537cf5c741df50eebb40a64233c3b9 478 Gene3D G3DSA:1.20.1740.10 9 473 5.4E-71 T 15-10-2018 C2I28_12315 a5537cf5c741df50eebb40a64233c3b9 478 Pfam PF00324 Amino acid permease 19 460 1.3E-124 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_23245 dda7677ca405b1faa529c50ffdf2139c 364 Gene3D G3DSA:3.20.20.70 3 351 2.1E-81 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_23245 dda7677ca405b1faa529c50ffdf2139c 364 SUPERFAMILY SSF51395 5 330 7.05E-73 T 15-10-2018 C2I28_23245 dda7677ca405b1faa529c50ffdf2139c 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 326 5.7E-59 T 15-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 C2I28_15770 8c90ee93d780e3a51d9035de12615276 484 Pfam PF02435 Levansucrase/Invertase 38 479 2.2E-154 T 15-10-2018 IPR003469 Glycoside hydrolase, family 68 GO:0009758|GO:0050053 C2I28_15770 8c90ee93d780e3a51d9035de12615276 484 Gene3D G3DSA:2.115.10.20 29 477 2.7E-195 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_15770 8c90ee93d780e3a51d9035de12615276 484 SUPERFAMILY SSF75005 38 482 8.85E-101 T 15-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 Gene3D G3DSA:1.20.1530.20 4 398 4.6E-71 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 Pfam PF00999 Sodium/hydrogen exchanger family 11 391 5.0E-77 T 15-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 SUPERFAMILY SSF51735 409 518 1.34E-12 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 Pfam PF02254 TrkA-N domain 409 516 2.9E-11 T 15-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 SUPERFAMILY SSF116726 547 611 4.32E-8 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 Pfam PF02080 TrkA-C domain 555 613 1.7E-9 T 15-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 Gene3D G3DSA:3.30.70.1450 535 617 4.6E-19 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_11840 15793f1cf1db5174627ecc92b44835ca 619 Gene3D G3DSA:3.40.50.720 399 534 4.2E-17 T 15-10-2018 C2I28_13765 d8bb49e3bcbb34790f0f43cd9607afe8 722 SUPERFAMILY SSF53756 477 719 9.73E-13 T 15-10-2018 C2I28_13765 d8bb49e3bcbb34790f0f43cd9607afe8 722 Gene3D G3DSA:3.40.50.12580 524 705 3.4E-23 T 15-10-2018 C2I28_13765 d8bb49e3bcbb34790f0f43cd9607afe8 722 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 366 717 5.8E-38 T 15-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 C2I28_18830 ac56e07723c6c8b552112c9dbb288e8d 41 SUPERFAMILY SSF47406 9 37 3.27E-8 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_18830 ac56e07723c6c8b552112c9dbb288e8d 41 Pfam PF08671 Anti-repressor SinI 10 36 5.4E-10 T 15-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I28_01955 d0478692a56ae30349338e631e89295f 163 PIRSF PIRSF021441 1 158 2.0E-71 T 15-10-2018 IPR031306 CcdC protein C2I28_01955 d0478692a56ae30349338e631e89295f 163 Pfam PF07301 Protein of unknown function (DUF1453) 4 147 3.4E-62 T 15-10-2018 IPR009916 Protein of unknown function DUF1453 C2I28_05115 79d752295eec2cabe4b909ec40089ceb 374 SUPERFAMILY SSF51679 1 347 1.7E-101 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_05115 79d752295eec2cabe4b909ec40089ceb 374 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 3 347 6.2E-190 T 15-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I28_05115 79d752295eec2cabe4b909ec40089ceb 374 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 372 77.969 T 15-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I28_05115 79d752295eec2cabe4b909ec40089ceb 374 Gene3D G3DSA:3.20.20.30 1 357 3.5E-153 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_05115 79d752295eec2cabe4b909ec40089ceb 374 Pfam PF00296 Luciferase-like monooxygenase 1 323 2.9E-92 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_20935 4ac83f3a02d2212a12f0c0dd194e8451 544 Pfam PF07728 AAA domain (dynein-related subfamily) 217 367 1.8E-5 T 15-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 C2I28_20935 4ac83f3a02d2212a12f0c0dd194e8451 544 Gene3D G3DSA:3.40.50.300 199 380 3.5E-19 T 15-10-2018 C2I28_20935 4ac83f3a02d2212a12f0c0dd194e8451 544 SUPERFAMILY SSF52540 154 378 9.53E-18 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20935 4ac83f3a02d2212a12f0c0dd194e8451 544 Pfam PF12102 Domain of unknown function (DUF3578) 10 168 1.5E-10 T 15-10-2018 IPR021961 Protein of unknown function DUF3578 C2I28_06175 dd7c6735c727f972749626319aa3b77b 225 PRINTS PR01837 MgtC/SapB protein signature 12 31 1.1E-41 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_06175 dd7c6735c727f972749626319aa3b77b 225 PRINTS PR01837 MgtC/SapB protein signature 65 87 1.1E-41 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_06175 dd7c6735c727f972749626319aa3b77b 225 PRINTS PR01837 MgtC/SapB protein signature 31 49 1.1E-41 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_06175 dd7c6735c727f972749626319aa3b77b 225 PRINTS PR01837 MgtC/SapB protein signature 93 117 1.1E-41 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_06175 dd7c6735c727f972749626319aa3b77b 225 Pfam PF02308 MgtC family 9 136 1.6E-34 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_15575 75e8d8aca6a2c853869d878cf68ecc33 326 Gene3D G3DSA:1.20.1260.10 1 145 8.3E-6 T 15-10-2018 IPR012347 Ferritin-like C2I28_15575 75e8d8aca6a2c853869d878cf68ecc33 326 Pfam PF11553 Protein of unknown function (DUF3231) 3 157 4.5E-32 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_15575 75e8d8aca6a2c853869d878cf68ecc33 326 Pfam PF11553 Protein of unknown function (DUF3231) 170 325 8.8E-35 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_00195 280ee7747b21248f1bd6bd00e53a0071 65 Gene3D G3DSA:1.10.1740.70 2 65 3.6E-26 T 15-10-2018 C2I28_00195 280ee7747b21248f1bd6bd00e53a0071 65 SUPERFAMILY SSF140376 2 65 1.44E-24 T 15-10-2018 IPR037205 ChaB superfamily C2I28_00195 280ee7747b21248f1bd6bd00e53a0071 65 Pfam PF06150 ChaB 9 65 2.1E-24 T 15-10-2018 IPR009317 ChaB C2I28_22880 7be4901614ec50bb15f7f515c00d03dc 426 Pfam PF07690 Major Facilitator Superfamily 17 257 6.8E-42 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_22880 7be4901614ec50bb15f7f515c00d03dc 426 Pfam PF07690 Major Facilitator Superfamily 262 417 2.1E-13 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_22880 7be4901614ec50bb15f7f515c00d03dc 426 Gene3D G3DSA:1.20.1250.20 1 204 2.4E-40 T 15-10-2018 C2I28_22880 7be4901614ec50bb15f7f515c00d03dc 426 Gene3D G3DSA:1.20.1250.20 222 419 1.4E-33 T 15-10-2018 C2I28_22880 7be4901614ec50bb15f7f515c00d03dc 426 SUPERFAMILY SSF103473 4 415 2.09E-80 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_22880 7be4901614ec50bb15f7f515c00d03dc 426 PIRSF PIRSF002808 1 423 4.2E-34 T 15-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I28_01770 390b0bb41733ba92993a06b7ce87f957 220 SUPERFAMILY SSF100950 6 216 3.35E-62 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_01770 390b0bb41733ba92993a06b7ce87f957 220 SMART SM00882 9 205 1.7E-55 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_01770 390b0bb41733ba92993a06b7ce87f957 220 Gene3D G3DSA:3.40.1080.10 5 217 1.2E-85 T 15-10-2018 C2I28_01770 390b0bb41733ba92993a06b7ce87f957 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 8 210 1.4E-89 T 15-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 C2I28_01770 390b0bb41733ba92993a06b7ce87f957 220 Pfam PF01144 Coenzyme A transferase 11 202 4.0E-35 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 Gene3D G3DSA:3.40.50.720 129 305 1.2E-78 T 15-10-2018 C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 92 2.1E-10 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 Pfam PF13602 Zinc-binding dehydrogenase 191 335 7.6E-20 T 15-10-2018 C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 SUPERFAMILY SSF51735 121 240 9.94E-27 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 Gene3D G3DSA:3.90.180.10 19 335 1.2E-78 T 15-10-2018 C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 SUPERFAMILY SSF50129 4 152 1.52E-33 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_16915 e51569d42d8bbcfcbd1ce9d18c1a063b 337 SMART SM00829 12 335 1.1E-13 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 Gene3D G3DSA:3.40.710.10 260 668 8.0E-113 T 15-10-2018 C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 Pfam PF00912 Transglycosylase 62 237 4.0E-66 T 15-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 SUPERFAMILY SSF56601 219 664 6.02E-115 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 610 8.7E-179 T 15-10-2018 C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 Pfam PF00905 Penicillin binding protein transpeptidase domain 329 573 2.1E-29 T 15-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 Gene3D G3DSA:1.10.3810.10 55 253 6.7E-78 T 15-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_07540 67ed420c307d7f9e96d096f2505d67ff 688 SUPERFAMILY SSF53955 50 259 6.75E-78 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_04015 b8fe8f02ee442398833429355197004e 112 ProDom PD073895 COMPETENCE COMGE LATE MACHINERY MEMBRANE OPERON DNA THE METHYLATION PART 6 84 0.001 T 15-10-2018 IPR020488 Competence operon G, ComGE C2I28_04015 b8fe8f02ee442398833429355197004e 112 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 29 4.5E-5 T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_04015 b8fe8f02ee442398833429355197004e 112 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 SUPERFAMILY SSF69737 76 141 6.15E-17 T 15-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 PIRSF PIRSF036402 1 148 4.0E-46 T 15-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 SUPERFAMILY SSF69287 1 73 2.35E-20 T 15-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 Pfam PF05194 UreE urease accessory protein, C-terminal domain 77 138 2.1E-8 T 15-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 Pfam PF02814 UreE urease accessory protein, N-terminal domain 16 69 1.6E-16 T 15-10-2018 IPR004029 UreE urease accessory, N-terminal C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 Hamap MF_00822 Urease accessory protein UreE [ureE]. 1 147 23.17 T 15-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 Gene3D G3DSA:2.60.260.20 1 73 1.5E-22 T 15-10-2018 C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 Gene3D G3DSA:3.30.70.790 75 147 3.4E-29 T 15-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 C2I28_22945 68ff28b4947cb2c75fecf4496d393186 148 SMART SM00988 6 69 2.9E-16 T 15-10-2018 IPR004029 UreE urease accessory, N-terminal C2I28_04710 40dcbf9c2527d4000d31411965e5cb2d 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.205 T 15-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 C2I28_04710 40dcbf9c2527d4000d31411965e5cb2d 170 SUPERFAMILY SSF53271 2 164 6.67E-50 T 15-10-2018 IPR029057 Phosphoribosyltransferase-like C2I28_04710 40dcbf9c2527d4000d31411965e5cb2d 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 170 9.8E-70 T 15-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 C2I28_04710 40dcbf9c2527d4000d31411965e5cb2d 170 Pfam PF00156 Phosphoribosyl transferase domain 28 151 1.3E-15 T 15-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 C2I28_04710 40dcbf9c2527d4000d31411965e5cb2d 170 Gene3D G3DSA:3.40.50.2020 1 170 1.6E-60 T 15-10-2018 C2I28_02410 96e61c0e40d06455f6c6bbec366b27b1 142 Gene3D G3DSA:2.30.30.40 4 129 1.8E-39 T 15-10-2018 C2I28_02410 96e61c0e40d06455f6c6bbec366b27b1 142 SMART SM00260 1 135 1.7E-32 T 15-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I28_02410 96e61c0e40d06455f6c6bbec366b27b1 142 Gene3D G3DSA:2.40.50.180 21 130 1.8E-39 T 15-10-2018 C2I28_02410 96e61c0e40d06455f6c6bbec366b27b1 142 SUPERFAMILY SSF50341 2 138 1.44E-36 T 15-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 C2I28_02410 96e61c0e40d06455f6c6bbec366b27b1 142 Pfam PF01584 CheW-like domain 3 136 9.7E-34 T 15-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 C2I28_22980 b8364be989fab21664febed31f380422 249 SUPERFAMILY SSF55469 1 248 2.49E-71 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_22980 b8364be989fab21664febed31f380422 249 PIRSF PIRSF005426 1 249 6.0E-94 T 15-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 C2I28_22980 b8364be989fab21664febed31f380422 249 Pfam PF00881 Nitroreductase family 8 165 3.2E-22 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_22980 b8364be989fab21664febed31f380422 249 Gene3D G3DSA:3.40.109.10 1 249 2.0E-83 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_19600 ede497c607646fae84f931688718696c 177 SUPERFAMILY SSF88723 5 129 1.07E-18 T 15-10-2018 IPR029060 PIN-like domain superfamily C2I28_19600 ede497c607646fae84f931688718696c 177 Pfam PF01850 PIN domain 6 127 3.2E-11 T 15-10-2018 IPR002716 PIN domain C2I28_19600 ede497c607646fae84f931688718696c 177 Gene3D G3DSA:3.40.50.1010 1 136 2.5E-21 T 15-10-2018 C2I28_26945 83c62cebf7c704886e0902a9f300d59c 62 Gene3D G3DSA:4.10.810.10 11 62 4.6E-19 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_26945 83c62cebf7c704886e0902a9f300d59c 62 Pfam PF08858 IDEAL domain 22 58 9.4E-13 T 15-10-2018 IPR014957 IDEAL domain C2I28_26945 83c62cebf7c704886e0902a9f300d59c 62 SMART SM00914 22 58 1.8E-8 T 15-10-2018 IPR014957 IDEAL domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SUPERFAMILY SSF47384 356 424 1.71E-12 T 15-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SMART SM00091 235 301 4.1E-10 T 15-10-2018 IPR000014 PAS domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SMART SM00091 110 175 0.0037 T 15-10-2018 IPR000014 PAS domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.4E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 1.4E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.4E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 571 1.4E-13 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Gene3D G3DSA:3.30.450.20 105 223 1.7E-18 T 15-10-2018 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 424 2.5E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 573 1.3E-22 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Gene3D G3DSA:1.10.287.130 348 424 5.8E-17 T 15-10-2018 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SMART SM00388 363 425 5.7E-14 T 15-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 113 230 1.1E-18 T 15-10-2018 IPR000014 PAS domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 231 353 3.9E-26 T 15-10-2018 IPR000014 PAS domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SMART SM00387 467 574 4.4E-29 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Gene3D G3DSA:3.30.450.20 224 346 5.3E-25 T 15-10-2018 C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Pfam PF13426 PAS domain 246 347 1.0E-10 T 15-10-2018 IPR000014 PAS domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Pfam PF13426 PAS domain 121 221 1.3E-8 T 15-10-2018 IPR000014 PAS domain C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SUPERFAMILY SSF55874 416 572 1.26E-34 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 Gene3D G3DSA:3.30.565.10 426 574 9.7E-41 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SUPERFAMILY SSF55785 121 232 5.06E-19 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_19815 25ef497fdb5ef4a4fe0af908e78e7a25 574 SUPERFAMILY SSF55785 220 346 1.36E-24 T 15-10-2018 IPR035965 PAS domain superfamily C2I28_08885 8ba92727e1ba105b6ef6243520732f98 208 Pfam PF14089 KinB-signalling pathway activation in sporulation 19 197 1.1E-77 T 15-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 C2I28_08885 8ba92727e1ba105b6ef6243520732f98 208 PIRSF PIRSF029886 3 201 2.4E-76 T 15-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 C2I28_08885 8ba92727e1ba105b6ef6243520732f98 208 SMART SM01251 19 198 1.4E-108 T 15-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 C2I28_07120 73fc7da1611a2858cb5aaa0779ba3744 76 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 66 17.849 T 15-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 C2I28_07120 73fc7da1611a2858cb5aaa0779ba3744 76 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 61 3.6E-29 T 15-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 C2I28_07120 73fc7da1611a2858cb5aaa0779ba3744 76 Pfam PF02599 Global regulator protein family 1 52 6.2E-27 T 15-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 C2I28_07120 73fc7da1611a2858cb5aaa0779ba3744 76 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-14 T 15-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 C2I28_07120 73fc7da1611a2858cb5aaa0779ba3744 76 SUPERFAMILY SSF117130 1 55 1.83E-20 T 15-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 C2I28_07120 73fc7da1611a2858cb5aaa0779ba3744 76 Gene3D G3DSA:3.30.70.1680 1 62 4.9E-29 T 15-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 C2I28_06465 f16be479cf1f569f70e5f66036e5539a 88 Pfam PF11256 Protein of unknown function (DUF3055) 7 86 3.0E-37 T 15-10-2018 IPR021415 Protein of unknown function DUF3055 C2I28_09100 6be701affd9df5e34653449955b07b5a 170 Gene3D G3DSA:3.90.1010.20 115 170 1.2E-8 T 15-10-2018 C2I28_09100 6be701affd9df5e34653449955b07b5a 170 SMART SM00900 88 167 1.8E-9 T 15-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 C2I28_09100 6be701affd9df5e34653449955b07b5a 170 Pfam PF04205 FMN-binding domain 98 165 5.3E-9 T 15-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 C2I28_26390 481b8b41c914fcbfaf82e624df582b7c 96 Pfam PF17332 Uncharacterized protein pXO2-11 4 92 1.2E-28 T 15-10-2018 IPR020275 Uncharacterised protein family, plasmid pXO2-11 C2I28_27240 481b8b41c914fcbfaf82e624df582b7c 96 Pfam PF17332 Uncharacterized protein pXO2-11 4 92 1.2E-28 T 15-10-2018 IPR020275 Uncharacterised protein family, plasmid pXO2-11 C2I28_27150 481b8b41c914fcbfaf82e624df582b7c 96 Pfam PF17332 Uncharacterized protein pXO2-11 4 92 1.2E-28 T 15-10-2018 IPR020275 Uncharacterised protein family, plasmid pXO2-11 C2I28_26290 481b8b41c914fcbfaf82e624df582b7c 96 Pfam PF17332 Uncharacterized protein pXO2-11 4 92 1.2E-28 T 15-10-2018 IPR020275 Uncharacterised protein family, plasmid pXO2-11 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 SUPERFAMILY SSF51316 179 317 7.32E-59 T 15-10-2018 IPR011057 Mss4-like superfamily C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 SUPERFAMILY SSF55068 3 170 6.15E-73 T 15-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 Gene3D G3DSA:2.170.150.20 174 320 5.1E-58 T 15-10-2018 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 164 36.935 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 Pfam PF01641 SelR domain 183 302 4.6E-48 T 15-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 6.1E-65 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 Gene3D G3DSA:3.30.1060.10 1 164 1.2E-66 T 15-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 180 311 1.8E-63 T 15-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 Pfam PF01625 Peptide methionine sulfoxide reductase 8 158 4.6E-61 T 15-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 C2I28_14150 2821ed72bf5d42a63920ef4399107334 320 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 170 303 36.727 T 15-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 1.7E-11 T 15-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 1.7E-11 T 15-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.7E-11 T 15-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 Gene3D G3DSA:1.10.1200.120 1 126 7.9E-42 T 15-10-2018 IPR036019 Gated mechanosensitive channel C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 SUPERFAMILY SSF81330 10 119 1.44E-35 T 15-10-2018 IPR036019 Gated mechanosensitive channel C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 15-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 124 24.381 T 15-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 123 5.6E-50 T 15-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 C2I28_09040 072f296a270a1b00aa82971ec004e90d 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 123 4.0E-45 T 15-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L C2I28_13750 8f70f79deecb366316570a2eb657807c 427 SUPERFAMILY SSF53756 18 426 5.23E-45 T 15-10-2018 C2I28_13750 8f70f79deecb366316570a2eb657807c 427 Gene3D G3DSA:3.40.50.2000 236 410 5.0E-31 T 15-10-2018 C2I28_13750 8f70f79deecb366316570a2eb657807c 427 Pfam PF00534 Glycosyl transferases group 1 238 402 3.4E-18 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.4E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.4E-7 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 Gene3D G3DSA:1.10.357.10 2 207 9.5E-39 T 15-10-2018 C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 SUPERFAMILY SSF46689 5 76 2.99E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 SUPERFAMILY SSF48498 79 173 1.63E-8 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_05590 9b484b03021aae6a794de38c85a738b2 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 5.9E-15 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_18845 a8577788e4cf5c577f2fad565cedd017 610 Gene3D G3DSA:3.40.50.720 273 607 3.7E-116 T 15-10-2018 C2I28_18845 a8577788e4cf5c577f2fad565cedd017 610 SUPERFAMILY SSF51735 275 539 2.76E-56 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18845 a8577788e4cf5c577f2fad565cedd017 610 Pfam PF02719 Polysaccharide biosynthesis protein 278 561 1.1E-121 T 15-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain C2I28_18845 a8577788e4cf5c577f2fad565cedd017 610 SUPERFAMILY SSF53335 102 302 3.65E-13 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_18845 a8577788e4cf5c577f2fad565cedd017 610 Gene3D G3DSA:3.40.50.720 132 259 3.1E-35 T 15-10-2018 C2I28_18845 a8577788e4cf5c577f2fad565cedd017 610 Pfam PF13727 CoA-binding domain 76 229 2.9E-13 T 15-10-2018 C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 Gene3D G3DSA:1.25.40.20 3 104 2.3E-12 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 Gene3D G3DSA:1.25.40.960 105 168 3.5E-9 T 15-10-2018 C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 Pfam PF12796 Ankyrin repeats (3 copies) 75 134 1.2E-9 T 15-10-2018 IPR020683 Ankyrin repeat-containing domain C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 SMART SM00248 104 133 4.4E-4 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 SMART SM00248 72 101 570.0 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 SMART SM00248 38 67 4.5 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 Pfam PF13606 Ankyrin repeat 43 66 1.5E-5 T 15-10-2018 IPR002110 Ankyrin repeat GO:0005515 C2I28_21490 500c915fc8b373f9932d9e7fe3668b55 170 SUPERFAMILY SSF48403 12 163 2.02E-23 T 15-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily C2I28_13165 1bc2b45858fc7325a88066ef7deec7f2 157 SUPERFAMILY SSF54427 43 155 1.3E-10 T 15-10-2018 IPR032710 NTF2-like domain superfamily C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 SUPERFAMILY SSF51735 6 251 1.68E-79 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 Gene3D G3DSA:3.40.50.720 1 251 1.0E-80 T 15-10-2018 C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.3E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.3E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-43 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.6E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.6E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.6E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 6.4E-63 T 15-10-2018 C2I28_22285 f935110aadbc53037ef20fd2bf141f83 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 Gene3D G3DSA:3.40.190.290 83 283 1.5E-72 T 15-10-2018 C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 1.4E-15 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 SUPERFAMILY SSF53850 89 282 4.34E-28 T 15-10-2018 C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 Pfam PF03466 LysR substrate binding domain 87 282 2.3E-30 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 Gene3D G3DSA:1.10.10.10 1 82 4.0E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 SUPERFAMILY SSF46785 1 111 9.05E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_00625 ee286b9fb3fbab61304fc36629dd3a5c 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_10785 0eb21af13c57c23fd290c87c4d353566 330 Gene3D G3DSA:3.30.360.10 126 330 1.6E-39 T 15-10-2018 C2I28_10785 0eb21af13c57c23fd290c87c4d353566 330 Gene3D G3DSA:3.40.50.720 4 125 7.4E-27 T 15-10-2018 C2I28_10785 0eb21af13c57c23fd290c87c4d353566 330 SUPERFAMILY SSF51735 5 154 2.45E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10785 0eb21af13c57c23fd290c87c4d353566 330 SUPERFAMILY SSF55347 130 248 2.88E-16 T 15-10-2018 C2I28_10785 0eb21af13c57c23fd290c87c4d353566 330 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 124 3.8E-18 T 15-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 Gene3D G3DSA:3.20.20.80 1 218 1.5E-65 T 15-10-2018 C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 Gene3D G3DSA:1.10.101.10 219 296 2.6E-16 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 Pfam PF01183 Glycosyl hydrolases family 25 13 191 1.3E-46 T 15-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 SMART SM00641 13 116 2.3E-9 T 15-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 SUPERFAMILY SSF51445 12 202 1.33E-50 T 15-10-2018 IPR017853 Glycoside hydrolase superfamily C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 SUPERFAMILY SSF47090 221 288 8.44E-16 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_19665 896a5e488bd3f9942ab1b56d867345da 298 Pfam PF01471 Putative peptidoglycan binding domain 231 287 1.0E-11 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_22860 75a8db18d7656e8f247fb6e0d2fd0a51 182 Gene3D G3DSA:3.40.50.10490 2 182 1.3E-52 T 15-10-2018 C2I28_22860 75a8db18d7656e8f247fb6e0d2fd0a51 182 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 5 182 7.1E-66 T 15-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 C2I28_22860 75a8db18d7656e8f247fb6e0d2fd0a51 182 Pfam PF01380 SIS domain 30 137 1.6E-20 T 15-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 C2I28_22860 75a8db18d7656e8f247fb6e0d2fd0a51 182 SUPERFAMILY SSF53697 5 181 2.83E-38 T 15-10-2018 C2I28_20870 80482449e92ded6bf8e494cab443e449 475 Gene3D G3DSA:3.30.870.10 266 443 2.3E-20 T 15-10-2018 C2I28_20870 80482449e92ded6bf8e494cab443e449 475 Pfam PF13091 PLD-like domain 296 438 3.0E-22 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_20870 80482449e92ded6bf8e494cab443e449 475 SUPERFAMILY SSF56024 62 271 9.03E-14 T 15-10-2018 C2I28_20870 80482449e92ded6bf8e494cab443e449 475 SUPERFAMILY SSF56024 289 457 1.7E-15 T 15-10-2018 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 PRINTS PR01166 Cytochrome c oxidase subunit II signature 87 99 1.1E-8 T 15-10-2018 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 PRINTS PR01166 Cytochrome c oxidase subunit II signature 215 232 1.1E-8 T 15-10-2018 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 PRINTS PR01166 Cytochrome c oxidase subunit II signature 197 214 1.1E-8 T 15-10-2018 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 1.1E-8 T 15-10-2018 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 34 242 8.1E-56 T 15-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 151 233 1.5E-15 T 15-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 Pfam PF00034 Cytochrome c 257 349 1.0E-11 T 15-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 Gene3D G3DSA:2.60.40.2600 124 351 6.3E-66 T 15-10-2018 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 SUPERFAMILY SSF46626 249 350 1.98E-18 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 SUPERFAMILY SSF81464 17 120 2.45E-21 T 15-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 SUPERFAMILY SSF49503 125 276 9.74E-41 T 15-10-2018 IPR008972 Cupredoxin C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 Gene3D G3DSA:1.10.287.90 28 119 1.0E-24 T 15-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 172 226 - T 15-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14905 76516ceceb93a6c077bed7de6ffc1716 351 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 50 110 1.3E-8 T 15-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_21015 813d6b6bd3644157d5ffaaa4c865798c 113 Pfam PF11345 Protein of unknown function (DUF3147) 10 103 2.1E-6 T 15-10-2018 IPR021493 Protein of unknown function DUF3147 C2I28_12010 9f431d5a585711cc1a163c741703b2de 463 PIRSF PIRSF006060 1 462 1.2E-83 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_12010 9f431d5a585711cc1a163c741703b2de 463 Gene3D G3DSA:1.20.1740.10 8 462 3.4E-74 T 15-10-2018 C2I28_12010 9f431d5a585711cc1a163c741703b2de 463 Pfam PF00324 Amino acid permease 17 444 1.5E-121 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_12010 9f431d5a585711cc1a163c741703b2de 463 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_05865 dd4a902388db4c570fadc5760ae27f1d 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 7.4E-35 T 15-10-2018 IPR019699 Protein of unknown function DUF2584 C2I28_05865 dd4a902388db4c570fadc5760ae27f1d 80 SUPERFAMILY SSF88697 1 80 6.46E-30 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_05865 dd4a902388db4c570fadc5760ae27f1d 80 Gene3D G3DSA:2.40.240.20 1 77 3.7E-33 T 15-10-2018 C2I28_09865 c2a4722f0ae8a823cc89ec5867fcdfdb 445 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 166 231 6.4E-8 T 15-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain C2I28_09865 c2a4722f0ae8a823cc89ec5867fcdfdb 445 Gene3D G3DSA:3.30.565.60 115 240 2.1E-14 T 15-10-2018 IPR038475 RecG, C-terminal domain superfamily C2I28_03885 d42f4f6666ef5e82f944cd65cefd4ba1 206 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 198 8.6E-37 T 15-10-2018 IPR014245 Sporulation stage III, protein AF C2I28_03885 d42f4f6666ef5e82f944cd65cefd4ba1 206 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 2 111 1.1E-34 T 15-10-2018 IPR014245 Sporulation stage III, protein AF C2I28_24170 240c66f26bfc056e992dd2242317f3f4 82 Pfam PF11007 Spore coat associated protein JA (CotJA) 35 67 1.1E-9 T 15-10-2018 IPR020256 Spore coat protein CotJA C2I28_24170 240c66f26bfc056e992dd2242317f3f4 82 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 12 78 9.0E-23 T 15-10-2018 IPR020256 Spore coat protein CotJA C2I28_22870 88216be600303819de57d5ee6371e46f 336 Gene3D G3DSA:3.40.50.2300 166 330 5.4E-75 T 15-10-2018 C2I28_22870 88216be600303819de57d5ee6371e46f 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 15-10-2018 C2I28_22870 88216be600303819de57d5ee6371e46f 336 SUPERFAMILY SSF47413 3 63 9.01E-17 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_22870 88216be600303819de57d5ee6371e46f 336 Gene3D G3DSA:1.10.260.40 3 63 3.2E-21 T 15-10-2018 C2I28_22870 88216be600303819de57d5ee6371e46f 336 SUPERFAMILY SSF53822 65 334 1.53E-73 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_22870 88216be600303819de57d5ee6371e46f 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 52 6.1E-17 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_22870 88216be600303819de57d5ee6371e46f 336 Pfam PF13377 Periplasmic binding protein-like domain 176 333 3.3E-30 T 15-10-2018 C2I28_22870 88216be600303819de57d5ee6371e46f 336 Gene3D G3DSA:3.40.50.2300 66 325 5.4E-75 T 15-10-2018 C2I28_22870 88216be600303819de57d5ee6371e46f 336 SMART SM00354 4 75 7.2E-32 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_19685 8ba8f55af188040a4d4865cf6d3e9cc5 43 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 20 41 2.6E-10 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_19685 8ba8f55af188040a4d4865cf6d3e9cc5 43 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 18 38 2.0E-6 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_10615 f43053de2d53de73fae78c423035f8a2 298 Gene3D G3DSA:3.20.20.150 2 295 1.7E-78 T 15-10-2018 C2I28_10615 f43053de2d53de73fae78c423035f8a2 298 Hamap MF_01672 Inosose dehydratase [iolE]. 2 298 57.064 T 15-10-2018 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 C2I28_10615 f43053de2d53de73fae78c423035f8a2 298 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 6 294 1.8E-127 T 15-10-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 C2I28_10615 f43053de2d53de73fae78c423035f8a2 298 SUPERFAMILY SSF51658 7 294 6.5E-55 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_10615 f43053de2d53de73fae78c423035f8a2 298 Pfam PF01261 Xylose isomerase-like TIM barrel 37 249 2.2E-22 T 15-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I28_07280 096a7b45f9de793eebb11f8f6a06f6bb 87 Gene3D G3DSA:1.10.10.60 1 87 4.1E-42 T 15-10-2018 C2I28_07280 096a7b45f9de793eebb11f8f6a06f6bb 87 Pfam PF12116 Stage III sporulation protein D 2 82 2.8E-41 T 15-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID C2I28_07280 096a7b45f9de793eebb11f8f6a06f6bb 87 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 15-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 C2I28_07280 096a7b45f9de793eebb11f8f6a06f6bb 87 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 2.6E-46 T 15-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID C2I28_05060 00c5dbcea113d88e408390bdb6d5f745 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 148 1.1E-30 T 15-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 C2I28_05060 00c5dbcea113d88e408390bdb6d5f745 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 142 9.2E-28 T 15-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 C2I28_05060 00c5dbcea113d88e408390bdb6d5f745 170 Gene3D G3DSA:3.60.21.10 1 167 4.3E-42 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_05060 00c5dbcea113d88e408390bdb6d5f745 170 SUPERFAMILY SSF56300 2 163 1.75E-39 T 15-10-2018 C2I28_11970 2c45069385216df5a9f7fee899fa028c 206 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 4 185 4.8E-35 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_02110 4d32a7238ed8863956c9d003c4c0faeb 465 Pfam PF13520 Amino acid permease 27 430 1.0E-58 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_02110 4d32a7238ed8863956c9d003c4c0faeb 465 Gene3D G3DSA:1.20.1740.10 22 465 1.4E-135 T 15-10-2018 C2I28_02110 4d32a7238ed8863956c9d003c4c0faeb 465 PIRSF PIRSF006060 5 465 4.5E-92 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_24215 bfd243b370a45c1e81ea55414d39ea9f 114 Pfam PF07457 Protein of unknown function (DUF1516) 12 106 7.6E-10 T 15-10-2018 IPR010899 Protein of unknown function UPF0344 C2I28_03085 05a91605f12db9f54b7f3143cd91f405 91 Hamap MF_01126 UPF0298 protein . 1 78 22.501 T 15-10-2018 IPR016979 Protein of unknown function DUF2129 C2I28_03085 05a91605f12db9f54b7f3143cd91f405 91 PIRSF PIRSF031653 1 91 5.6E-35 T 15-10-2018 IPR016979 Protein of unknown function DUF2129 C2I28_03085 05a91605f12db9f54b7f3143cd91f405 91 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 2.5E-31 T 15-10-2018 IPR016979 Protein of unknown function DUF2129 C2I28_10910 4bee995a0e21efd7f550cee13badb16d 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 42.168 T 15-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 C2I28_10910 4bee995a0e21efd7f550cee13badb16d 255 Gene3D G3DSA:3.20.20.70 1 255 6.9E-118 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_10910 4bee995a0e21efd7f550cee13badb16d 255 SUPERFAMILY SSF110399 1 240 8.76E-84 T 15-10-2018 C2I28_10910 4bee995a0e21efd7f550cee13badb16d 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 3 248 7.3E-111 T 15-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 C2I28_24445 567ac18313d44e9b93c522fddf41922c 161 Pfam PF11181 Heat induced stress protein YflT 9 139 8.4E-15 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_19375 a961561680117ee4e817335cddfb5dbe 453 Gene3D G3DSA:1.10.4160.10 1 449 9.0E-72 T 15-10-2018 IPR038271 Purine-cytosine permease superfamily C2I28_19375 a961561680117ee4e817335cddfb5dbe 453 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 14 415 2.9E-45 T 15-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 C2I28_19375 a961561680117ee4e817335cddfb5dbe 453 PIRSF PIRSF002744 2 440 2.4E-60 T 15-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 C2I28_12255 353e0eb138552b22631537a65f0ef350 251 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 1 246 3.0E-94 T 15-10-2018 IPR005226 UPF0014 family C2I28_12255 353e0eb138552b22631537a65f0ef350 251 Pfam PF03649 Uncharacterised protein family (UPF0014) 5 240 7.0E-78 T 15-10-2018 IPR005226 UPF0014 family C2I28_18650 5735a65445ba985efc5ce8bd57e039eb 396 Pfam PF13791 Sigma factor regulator C-terminal 219 377 6.9E-35 T 15-10-2018 IPR025672 Sigma factor regulator C-terminal domain C2I28_18650 5735a65445ba985efc5ce8bd57e039eb 396 Pfam PF13800 Sigma factor regulator N-terminal 71 160 3.7E-18 T 15-10-2018 IPR029101 Sigma factor regulator, N-terminal C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 SMART SM00357 3 65 1.1E-27 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 SUPERFAMILY SSF50249 1 64 3.43E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 Gene3D G3DSA:2.40.50.140 1 65 1.1E-30 T 15-10-2018 C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.0E-30 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 PRINTS PR00050 Cold shock protein signature 39 57 5.6E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 PRINTS PR00050 Cold shock protein signature 4 19 5.6E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 PRINTS PR00050 Cold shock protein signature 24 33 5.6E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_23970 5f740f8378d75b9207ac8acbed2f34fc 65 PIRSF PIRSF002599 1 65 1.7E-24 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_12020 669f75e8450c2d9ac9d8ae2bd417e0d3 240 SUPERFAMILY SSF56281 7 230 6.29E-39 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_12020 669f75e8450c2d9ac9d8ae2bd417e0d3 240 Pfam PF00753 Metallo-beta-lactamase superfamily 18 214 3.6E-24 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_12020 669f75e8450c2d9ac9d8ae2bd417e0d3 240 SMART SM00849 20 214 6.0E-28 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_12020 669f75e8450c2d9ac9d8ae2bd417e0d3 240 Gene3D G3DSA:3.60.15.10 7 239 5.2E-36 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_12790 27b905401cff2f0af88d646f535cce82 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.5E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12790 27b905401cff2f0af88d646f535cce82 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.5E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12790 27b905401cff2f0af88d646f535cce82 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 4.5E-5 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12790 27b905401cff2f0af88d646f535cce82 141 SMART SM00347 27 127 4.4E-26 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12790 27b905401cff2f0af88d646f535cce82 141 Gene3D G3DSA:1.10.10.10 4 139 3.5E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12790 27b905401cff2f0af88d646f535cce82 141 Pfam PF01047 MarR family 34 92 4.3E-15 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_12790 27b905401cff2f0af88d646f535cce82 141 SUPERFAMILY SSF46785 11 140 2.27E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 333 5.0E-117 T 15-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 SMART SM00922 143 235 2.9E-22 T 15-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 Gene3D G3DSA:3.20.20.120 118 347 2.1E-133 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 SUPERFAMILY SSF54826 1 126 1.01E-30 T 15-10-2018 C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 125 2.5E-11 T 15-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 Pfam PF13378 Enolase C-terminal domain-like 149 355 1.8E-49 T 15-10-2018 IPR029065 Enolase C-terminal domain-like C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 Gene3D G3DSA:3.30.390.10 8 358 2.1E-133 T 15-10-2018 IPR029017 Enolase-like, N-terminal C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 SUPERFAMILY SSF51604 114 363 2.75E-68 T 15-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily C2I28_13470 72a8530b5a2ab0e912a9dc55ed8e53ce 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 360 45.623 T 15-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 C2I28_01700 2079f38d7f3a978713b26fe89aa450f1 107 ProDom PD030115 YODL GK1575 1 107 2.0E-25 T 15-10-2018 C2I28_20930 518a9d9c21d27c3091ab71888fa67e81 570 Pfam PF04411 PD-(D/E)XK nuclease superfamily 386 522 9.4E-30 T 15-10-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 C2I28_20930 518a9d9c21d27c3091ab71888fa67e81 570 Pfam PF09823 Domain of unknown function (DUF2357) 114 363 3.2E-42 T 15-10-2018 IPR018633 Domain of unknown function DUF2357 C2I28_13880 9f4b579b7a905f65a2f8679b67c329b0 287 Pfam PF06800 Sugar transport protein 4 282 1.6E-97 T 15-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 C2I28_13880 9f4b579b7a905f65a2f8679b67c329b0 287 SUPERFAMILY SSF103481 35 138 1.83E-9 T 15-10-2018 C2I28_18855 bceeddef1468cd3cb9d12f7851a6133d 355 SUPERFAMILY SSF53448 3 255 1.55E-54 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18855 bceeddef1468cd3cb9d12f7851a6133d 355 Gene3D G3DSA:3.90.550.10 1 219 2.8E-56 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18855 bceeddef1468cd3cb9d12f7851a6133d 355 Pfam PF00535 Glycosyl transferase family 2 6 125 7.1E-33 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_22615 b172f2f27b5defe223e7c804224e723d 355 SUPERFAMILY SSF82171 58 349 8.63E-21 T 15-10-2018 C2I28_22615 b172f2f27b5defe223e7c804224e723d 355 Pfam PF07676 WD40-like Beta Propeller Repeat 279 292 0.031 T 15-10-2018 IPR011659 WD40-like Beta Propeller C2I28_22615 b172f2f27b5defe223e7c804224e723d 355 Gene3D G3DSA:2.120.10.30 214 354 1.2E-14 T 15-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I28_21710 83bb6ec862e24965c483ce3e44a5d7f9 185 SUPERFAMILY SSF54106 27 70 4.45E-13 T 15-10-2018 C2I28_21710 83bb6ec862e24965c483ce3e44a5d7f9 185 Pfam PF01476 LysM domain 29 70 1.6E-16 T 15-10-2018 IPR018392 LysM domain C2I28_21710 83bb6ec862e24965c483ce3e44a5d7f9 185 SUPERFAMILY SSF50685 126 171 4.88E-6 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_21710 83bb6ec862e24965c483ce3e44a5d7f9 185 Gene3D G3DSA:3.10.350.10 24 77 1.7E-21 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_21710 83bb6ec862e24965c483ce3e44a5d7f9 185 SMART SM00257 28 71 1.1E-17 T 15-10-2018 IPR018392 LysM domain C2I28_21710 83bb6ec862e24965c483ce3e44a5d7f9 185 Pfam PF06725 3D domain 125 185 8.7E-20 T 15-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I28_10805 dad686c47dd94c02dd168f5c3d128cbd 184 PIRSF PIRSF016897 1 184 1.2E-66 T 15-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I28_10805 dad686c47dd94c02dd168f5c3d128cbd 184 Gene3D G3DSA:3.20.20.400 1 183 5.1E-71 T 15-10-2018 IPR035928 GlpP-like superfamily C2I28_10805 dad686c47dd94c02dd168f5c3d128cbd 184 SUPERFAMILY SSF110391 8 181 2.48E-62 T 15-10-2018 IPR035928 GlpP-like superfamily C2I28_10805 dad686c47dd94c02dd168f5c3d128cbd 184 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 4.4E-66 T 15-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I28_23025 3d4bed04e05324495d670932370a8810 132 Pfam PF13115 YtkA-like 31 115 5.1E-14 T 15-10-2018 IPR032693 YtkA-like domain C2I28_16875 bea7ac0c103acd3b4424bdb620929daf 191 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 17 170 1.8E-17 T 15-10-2018 IPR025847 MEDS domain C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 PIRSF PIRSF003314 1 340 1.6E-119 T 15-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 SUPERFAMILY SSF51395 22 347 1.14E-82 T 15-10-2018 C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 Pfam PF01070 FMN-dependent dehydrogenase 166 323 1.5E-19 T 15-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 2.8E-115 T 15-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 Gene3D G3DSA:3.20.20.70 2 349 1.2E-124 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 37.015 T 15-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 C2I28_03285 bb40793c09ef2ca39777200f3a429509 349 SMART SM01240 23 333 0.0037 T 15-10-2018 C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 Gene3D G3DSA:2.40.50.140 298 343 1.9E-23 T 15-10-2018 C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 SUPERFAMILY SSF50331 237 359 1.58E-24 T 15-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 Gene3D G3DSA:2.40.50.100 240 355 1.9E-23 T 15-10-2018 C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 SUPERFAMILY SSF52540 4 243 4.76E-86 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 SMART SM00382 29 212 1.2E-15 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 Pfam PF00005 ABC transporter 21 162 1.1E-30 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15250 e4c468e0c02037f663123ed0d457041b 363 Gene3D G3DSA:3.40.50.300 1 239 6.4E-77 T 15-10-2018 C2I28_05570 01dd1f4a06c3e3f123975400bded3da4 380 SUPERFAMILY SSF53383 1 374 2.1E-101 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_05570 01dd1f4a06c3e3f123975400bded3da4 380 Gene3D G3DSA:3.90.1150.10 2 368 1.7E-134 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_05570 01dd1f4a06c3e3f123975400bded3da4 380 Gene3D G3DSA:3.40.640.10 59 234 1.7E-134 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_05570 01dd1f4a06c3e3f123975400bded3da4 380 Pfam PF00266 Aminotransferase class-V 2 361 6.2E-81 T 15-10-2018 IPR000192 Aminotransferase class V domain C2I28_05570 01dd1f4a06c3e3f123975400bded3da4 380 PIRSF PIRSF005572 1 379 6.5E-118 T 15-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 C2I28_05570 01dd1f4a06c3e3f123975400bded3da4 380 Gene3D G3DSA:1.10.260.50 13 277 1.7E-134 T 15-10-2018 C2I28_12325 3d96b28921764b9b98d44ac275f70058 240 Gene3D G3DSA:3.40.50.300 2 220 1.5E-48 T 15-10-2018 C2I28_12325 3d96b28921764b9b98d44ac275f70058 240 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 205 23.297 T 15-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 C2I28_12325 3d96b28921764b9b98d44ac275f70058 240 SUPERFAMILY SSF52540 3 208 3.05E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12325 3d96b28921764b9b98d44ac275f70058 240 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 174 7.0E-36 T 15-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 C2I28_12325 3d96b28921764b9b98d44ac275f70058 240 PIRSF PIRSF006755 1 230 2.0E-48 T 15-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 C2I28_12325 3d96b28921764b9b98d44ac275f70058 240 Pfam PF13500 AAA domain 3 204 5.9E-33 T 15-10-2018 C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 Gene3D G3DSA:3.90.1150.10 8 424 3.7E-151 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 PIRSF PIRSF000521 19 131 6.2E-8 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 PIRSF PIRSF000521 123 431 1.7E-42 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 Gene3D G3DSA:3.40.640.10 61 327 3.7E-151 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 SUPERFAMILY SSF53383 24 429 7.61E-129 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_12910 49819178b891a1ad8ab75a936b2228e9 439 Pfam PF00202 Aminotransferase class-III 22 428 1.8E-135 T 15-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 C2I28_14260 ca1dbc423835ac21608bfb691f4ec20b 237 Hamap MF_02104 Lactate utilization protein C [lutC]. 4 234 47.416 T 15-10-2018 IPR022823 Lactate utilization protein C C2I28_14260 ca1dbc423835ac21608bfb691f4ec20b 237 SUPERFAMILY SSF100950 46 234 1.55E-40 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_14260 ca1dbc423835ac21608bfb691f4ec20b 237 Gene3D G3DSA:3.40.50.10420 45 235 3.2E-38 T 15-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily C2I28_14260 ca1dbc423835ac21608bfb691f4ec20b 237 Pfam PF02589 LUD domain 53 234 1.6E-31 T 15-10-2018 IPR003741 LUD domain C2I28_16965 4cc3d9495d07191f5e9310d418fdcdd8 328 Pfam PF03773 Predicted permease 40 324 2.0E-70 T 15-10-2018 IPR005524 Predicted permease DUF318 C2I28_13525 7915a699649ebf84c3780c26786ec237 330 Pfam PF11553 Protein of unknown function (DUF3231) 3 159 9.4E-42 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_13525 7915a699649ebf84c3780c26786ec237 330 Pfam PF11553 Protein of unknown function (DUF3231) 171 329 1.7E-37 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_13525 7915a699649ebf84c3780c26786ec237 330 Gene3D G3DSA:1.20.1260.10 172 317 2.0E-5 T 15-10-2018 IPR012347 Ferritin-like C2I28_13840 f8348f6602644fddfb8671871ee43208 163 SUPERFAMILY SSF88659 106 158 1.72E-11 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_13840 f8348f6602644fddfb8671871ee43208 163 Pfam PF08281 Sigma-70, region 4 105 156 5.5E-8 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_13840 f8348f6602644fddfb8671871ee43208 163 SUPERFAMILY SSF88946 5 71 3.01E-14 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_13840 f8348f6602644fddfb8671871ee43208 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 158 2.6E-23 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_13840 f8348f6602644fddfb8671871ee43208 163 Pfam PF04542 Sigma-70 region 2 11 72 7.5E-14 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_13840 f8348f6602644fddfb8671871ee43208 163 Gene3D G3DSA:1.10.10.10 28 163 7.9E-30 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 Pfam PF01047 MarR family 36 92 4.4E-17 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 Gene3D G3DSA:1.10.10.10 2 138 9.6E-29 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 SMART SM00347 27 127 6.8E-21 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 6.5E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.5E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 6.5E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.5E-11 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_25655 de0b95e92b1893fb350c14823b939c6a 139 SUPERFAMILY SSF46785 13 137 2.08E-27 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_05840 d32cbdea518c6d62c5f8351306ebe8ea 175 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 7.1E-7 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_05840 d32cbdea518c6d62c5f8351306ebe8ea 175 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 44 3.8E-5 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_05840 d32cbdea518c6d62c5f8351306ebe8ea 175 Gene3D G3DSA:2.160.10.10 1 175 6.2E-75 T 15-10-2018 C2I28_05840 d32cbdea518c6d62c5f8351306ebe8ea 175 SUPERFAMILY SSF51161 2 169 5.37E-49 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_15945 72712143ce01a2882e9179877b0d4909 281 SUPERFAMILY SSF53850 30 267 1.21E-39 T 15-10-2018 C2I28_15945 72712143ce01a2882e9179877b0d4909 281 SMART SM00062 34 264 2.8E-25 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_15945 72712143ce01a2882e9179877b0d4909 281 Gene3D G3DSA:3.40.190.10 104 226 8.5E-50 T 15-10-2018 C2I28_15945 72712143ce01a2882e9179877b0d4909 281 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 262 7.9E-37 T 15-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF C2I28_15945 72712143ce01a2882e9179877b0d4909 281 Gene3D G3DSA:3.40.190.10 42 261 8.5E-50 T 15-10-2018 C2I28_10340 359aa72adca17f9c152de8192b78e0bc 295 Pfam PF12671 Putative amidase domain 137 288 1.4E-36 T 15-10-2018 IPR024301 Putative amidase domain C2I28_23910 17e94423653fefc4cdc40161a8f736f7 283 Pfam PF05569 BlaR1 peptidase M56 61 246 3.0E-17 T 15-10-2018 IPR008756 Peptidase M56 C2I28_23910 17e94423653fefc4cdc40161a8f736f7 283 Gene3D G3DSA:3.30.2010.10 82 171 1.4E-9 T 15-10-2018 C2I28_01040 2799f1a8cc034c62261359b81387bcb4 469 Gene3D G3DSA:3.30.565.40 26 149 6.6E-9 T 15-10-2018 C2I28_01040 2799f1a8cc034c62261359b81387bcb4 469 Pfam PF11738 Protein of unknown function (DUF3298) 153 219 1.4E-10 T 15-10-2018 IPR021729 Domain of unknown function DUF3298 C2I28_01040 2799f1a8cc034c62261359b81387bcb4 469 SUPERFAMILY SSF88713 261 456 2.45E-58 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_01040 2799f1a8cc034c62261359b81387bcb4 469 Gene3D G3DSA:3.20.20.370 238 465 3.7E-65 T 15-10-2018 C2I28_01040 2799f1a8cc034c62261359b81387bcb4 469 Gene3D G3DSA:3.90.640.20 151 237 1.4E-16 T 15-10-2018 IPR037126 PdaC/RsiV-like superfamily C2I28_01040 2799f1a8cc034c62261359b81387bcb4 469 Pfam PF01522 Polysaccharide deacetylase 273 393 6.9E-34 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_18930 3a55049a0c2bb2bcf4f31afe42e0197f 394 Gene3D G3DSA:1.50.10.10 35 388 4.3E-33 T 15-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 C2I28_18930 3a55049a0c2bb2bcf4f31afe42e0197f 394 SUPERFAMILY SSF48208 84 348 6.46E-26 T 15-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 C2I28_18930 3a55049a0c2bb2bcf4f31afe42e0197f 394 Pfam PF07470 Glycosyl Hydrolase Family 88 80 355 1.9E-22 T 15-10-2018 IPR010905 Glycosyl hydrolase, family 88 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 Gene3D G3DSA:3.60.20.40 356 536 9.7E-71 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 Pfam PF01019 Gamma-glutamyltranspeptidase 37 531 3.6E-159 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 22 528 1.7E-110 T 15-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 SUPERFAMILY SSF56235 4 536 1.93E-180 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 Gene3D G3DSA:1.10.246.130 251 355 1.5E-24 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 283 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 355 373 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 410 425 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 434 451 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 235 251 3.2E-43 T 15-10-2018 C2I28_24500 129e4f8be3b6d11a18843cb78abe407a 536 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 379 397 3.2E-43 T 15-10-2018 C2I28_01200 1cb3ce77677051b82062adad45af5132 316 SMART SM00382 27 214 5.0E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_01200 1cb3ce77677051b82062adad45af5132 316 Gene3D G3DSA:3.40.50.300 1 296 1.7E-79 T 15-10-2018 C2I28_01200 1cb3ce77677051b82062adad45af5132 316 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_01200 1cb3ce77677051b82062adad45af5132 316 SUPERFAMILY SSF52540 1 242 1.26E-79 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_01200 1cb3ce77677051b82062adad45af5132 316 Pfam PF00005 ABC transporter 18 164 2.8E-34 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_11000 9a1da78806ae9232f5bb8af182c0bdea 499 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 90 492 9.8E-150 T 15-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ C2I28_11000 9a1da78806ae9232f5bb8af182c0bdea 499 Gene3D G3DSA:3.80.30.20 130 491 1.8E-65 T 15-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I28_11000 9a1da78806ae9232f5bb8af182c0bdea 499 Pfam PF04055 Radical SAM superfamily 181 353 2.0E-16 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_11000 9a1da78806ae9232f5bb8af182c0bdea 499 SMART SM00729 173 397 4.4E-43 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_11000 9a1da78806ae9232f5bb8af182c0bdea 499 SUPERFAMILY SSF102114 160 484 4.19E-67 T 15-10-2018 C2I28_11820 1a3b1c000857f560594261d14d7d6ebe 268 Pfam PF01513 ATP-NAD kinase 26 188 1.2E-25 T 15-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I28_11820 1a3b1c000857f560594261d14d7d6ebe 268 SUPERFAMILY SSF111331 19 264 8.76E-65 T 15-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I28_11820 1a3b1c000857f560594261d14d7d6ebe 268 Hamap MF_00361 NAD kinase [nadK]. 4 266 24.166 T 15-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I28_11820 1a3b1c000857f560594261d14d7d6ebe 268 Gene3D G3DSA:2.60.200.30 105 243 1.7E-97 T 15-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 C2I28_11820 1a3b1c000857f560594261d14d7d6ebe 268 Gene3D G3DSA:3.40.50.10330 19 265 1.7E-97 T 15-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I28_21810 394a16a1a1f6a5b8f374aefc6fe14139 175 Gene3D G3DSA:3.40.1580.20 1 173 3.3E-16 T 15-10-2018 IPR038228 Syd superfamily C2I28_21810 394a16a1a1f6a5b8f374aefc6fe14139 175 Pfam PF07348 Syd protein (SUKH-2) 3 172 5.4E-31 T 15-10-2018 IPR009948 Syd GO:0009898 C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 Pfam PF00083 Sugar (and other) transporter 21 224 1.6E-27 T 15-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 SUPERFAMILY SSF103473 15 424 4.19E-68 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 312 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 Pfam PF07690 Major Facilitator Superfamily 249 430 7.0E-12 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 Gene3D G3DSA:1.20.1250.20 17 441 1.0E-71 T 15-10-2018 C2I28_17105 1a46cb1f00b7b6af62154b065093b284 448 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 92 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 227 2.4E-60 T 15-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 SMART SM00934 4 229 6.3E-84 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 226 2.1E-45 T 15-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 37.74 T 15-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 Gene3D G3DSA:3.20.20.70 1 239 1.4E-78 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 15-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 C2I28_02820 1aac5ba3743aea9fffedba62c4636dc9 240 SUPERFAMILY SSF51366 2 233 3.6E-67 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 Pfam PF01039 Carboxyl transferase domain 66 249 3.0E-21 T 15-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 Gene3D G3DSA:3.90.226.10 34 287 1.8E-89 T 15-10-2018 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 SUPERFAMILY SSF52096 34 285 1.6E-80 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 257 266 5.2E-38 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 235 246 5.2E-38 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 135 149 5.2E-38 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 169 187 5.2E-38 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 206 223 5.2E-38 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 287 38.847 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_05435 8821d5cd1735b64c0859055dd05052ca 293 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 25 288 5.5E-129 T 15-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 C2I28_08610 cddf7c081a1ae542b96df0f12f533b7c 59 Gene3D G3DSA:1.20.5.1030 1 58 6.9E-19 T 15-10-2018 IPR038379 SecE superfamily C2I28_08610 cddf7c081a1ae542b96df0f12f533b7c 59 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 7 35 - T 15-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08610 cddf7c081a1ae542b96df0f12f533b7c 59 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 6 58 1.7E-23 T 15-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 C2I28_08610 cddf7c081a1ae542b96df0f12f533b7c 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 2 57 13.019 T 15-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_08610 cddf7c081a1ae542b96df0f12f533b7c 59 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 6 58 1.1E-20 T 15-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 C2I28_09740 0d02e376b0f3f20d031c0d6edcad48a1 250 Gene3D G3DSA:3.40.50.1820 20 244 1.6E-47 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_09740 0d02e376b0f3f20d031c0d6edcad48a1 250 Pfam PF01764 Lipase (class 3) 67 196 3.7E-31 T 15-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 C2I28_09740 0d02e376b0f3f20d031c0d6edcad48a1 250 SUPERFAMILY SSF53474 11 211 4.96E-38 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_03500 00073c0f133b0b082dae2b712ecf4596 343 Gene3D G3DSA:3.40.47.40 1 342 1.4E-154 T 15-10-2018 IPR038369 Stage V sporulation AD superfamily C2I28_03500 00073c0f133b0b082dae2b712ecf4596 343 PIRSF PIRSF011570 1 334 3.4E-164 T 15-10-2018 IPR010894 Stage V sporulation AD C2I28_03500 00073c0f133b0b082dae2b712ecf4596 343 SUPERFAMILY SSF53901 56 309 4.24E-17 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_03500 00073c0f133b0b082dae2b712ecf4596 343 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 332 2.2E-161 T 15-10-2018 IPR010894 Stage V sporulation AD C2I28_03500 00073c0f133b0b082dae2b712ecf4596 343 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 332 8.4E-152 T 15-10-2018 IPR010894 Stage V sporulation AD C2I28_11145 4f45fa27864c6555e43430169f52816b 168 SUPERFAMILY SSF54909 67 166 3.22E-21 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_11145 4f45fa27864c6555e43430169f52816b 168 Pfam PF03992 Antibiotic biosynthesis monooxygenase 67 140 4.6E-11 T 15-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I28_11145 4f45fa27864c6555e43430169f52816b 168 Gene3D G3DSA:3.30.70.3430 1 168 2.9E-64 T 15-10-2018 C2I28_20790 73686e588bd72cef7ed191947a4e255c 472 SUPERFAMILY SSF53067 9 266 1.13E-9 T 15-10-2018 C2I28_20790 73686e588bd72cef7ed191947a4e255c 472 PIRSF PIRSF012293 2 472 3.9E-126 T 15-10-2018 IPR009377 Ethanolamine utilisation EutA C2I28_20790 73686e588bd72cef7ed191947a4e255c 472 Pfam PF06277 Ethanolamine utilisation protein EutA 6 470 9.6E-141 T 15-10-2018 IPR009377 Ethanolamine utilisation EutA C2I28_26520 f5304aefd6f7004e5b4218c4bdda3038 274 SUPERFAMILY SSF102198 3 272 4.58E-53 T 15-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I28_26520 f5304aefd6f7004e5b4218c4bdda3038 274 Pfam PF04199 Putative cyclase 5 203 4.0E-37 T 15-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I28_26520 f5304aefd6f7004e5b4218c4bdda3038 274 Gene3D G3DSA:3.50.30.50 47 274 1.1E-60 T 15-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 C2I28_12110 6a6f93412b71efa07cb90c8797ec0b0c 393 Pfam PF07690 Major Facilitator Superfamily 15 242 2.2E-27 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_12110 6a6f93412b71efa07cb90c8797ec0b0c 393 SUPERFAMILY SSF103473 3 378 7.06E-61 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_12110 6a6f93412b71efa07cb90c8797ec0b0c 393 Gene3D G3DSA:1.20.1250.20 3 184 4.7E-44 T 15-10-2018 C2I28_12110 6a6f93412b71efa07cb90c8797ec0b0c 393 Gene3D G3DSA:1.20.1250.20 193 388 3.0E-52 T 15-10-2018 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 4.1E-14 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 Gene3D G3DSA:1.10.10.10 2 91 3.8E-16 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 SUPERFAMILY SSF53850 105 288 6.52E-20 T 15-10-2018 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 SUPERFAMILY SSF46785 1 79 4.77E-17 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-5 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 Gene3D G3DSA:3.40.190.290 105 290 6.0E-14 T 15-10-2018 C2I28_13005 3f261fc27680069d2cb2b498a1fd70e2 291 Pfam PF03466 LysR substrate binding domain 128 288 3.1E-20 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_04790 a352a875030954c7d74379ede11badc3 290 Gene3D G3DSA:3.90.1200.10 71 289 5.2E-13 T 15-10-2018 C2I28_04790 a352a875030954c7d74379ede11badc3 290 Pfam PF01636 Phosphotransferase enzyme family 147 204 1.9E-6 T 15-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I28_04790 a352a875030954c7d74379ede11badc3 290 SUPERFAMILY SSF56112 7 214 4.92E-15 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_17110 966abf82a1873b4f351e6ccefbc45a69 322 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 42 243 1.4E-43 T 15-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 C2I28_17110 966abf82a1873b4f351e6ccefbc45a69 322 SUPERFAMILY SSF53474 38 318 3.32E-37 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_17110 966abf82a1873b4f351e6ccefbc45a69 322 Pfam PF10503 Esterase PHB depolymerase 41 237 7.3E-56 T 15-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 C2I28_17110 966abf82a1873b4f351e6ccefbc45a69 322 Gene3D G3DSA:3.40.50.1820 36 322 1.1E-55 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_26730 3cc418cc40fccf9ebfddf57b18737c9d 146 Gene3D G3DSA:2.30.110.10 10 138 1.4E-12 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_26730 3cc418cc40fccf9ebfddf57b18737c9d 146 SUPERFAMILY SSF50475 12 139 4.71E-15 T 15-10-2018 C2I28_02030 496d188ff63ea6f23aa00af47774a0ae 415 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 48 171 1.1E-10 T 15-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I28_23795 8b8a13f600a6394ffe0a8d611538fb33 206 SUPERFAMILY SSF53335 10 159 1.16E-28 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_23795 8b8a13f600a6394ffe0a8d611538fb33 206 Pfam PF08241 Methyltransferase domain 48 138 8.9E-21 T 15-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I28_23795 8b8a13f600a6394ffe0a8d611538fb33 206 Gene3D G3DSA:3.40.50.150 3 187 5.8E-30 T 15-10-2018 C2I28_16580 c7ab97e263e13ca5607de042539fe946 124 Gene3D G3DSA:2.60.40.420 28 124 1.1E-38 T 15-10-2018 IPR008972 Cupredoxin C2I28_16580 c7ab97e263e13ca5607de042539fe946 124 SUPERFAMILY SSF49503 39 124 1.27E-20 T 15-10-2018 IPR008972 Cupredoxin C2I28_16580 c7ab97e263e13ca5607de042539fe946 124 Pfam PF13473 Cupredoxin-like domain 31 123 4.3E-25 T 15-10-2018 IPR028096 EfeO-type cupredoxin-like domain C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 SUPERFAMILY SSF52317 477 711 8.39E-16 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 Gene3D G3DSA:3.40.50.880 33 333 1.7E-67 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 Gene3D G3DSA:3.40.50.880 459 753 2.1E-68 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 SUPERFAMILY SSF52317 62 288 7.85E-13 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 464 722 1.1E-49 T 15-10-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 37 308 1.6E-47 T 15-10-2018 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 Pfam PF03575 Peptidase family S51 464 700 8.3E-8 T 15-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 C2I28_16040 5948ca3bad06cbc8019c95621ad560d5 850 Pfam PF03575 Peptidase family S51 38 282 1.2E-7 T 15-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 C2I28_14710 ac54365c1d801c926c0e9fadb123db89 182 PIRSF PIRSF000239 1 182 1.4E-58 T 15-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_14710 ac54365c1d801c926c0e9fadb123db89 182 Gene3D G3DSA:3.40.30.10 1 182 6.2E-73 T 15-10-2018 C2I28_14710 ac54365c1d801c926c0e9fadb123db89 182 SUPERFAMILY SSF52833 5 180 8.89E-58 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_14710 ac54365c1d801c926c0e9fadb123db89 182 Pfam PF00578 AhpC/TSA family 6 141 7.9E-38 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_10845 2b7963a3e103df4bfa66f8ef3669c4d0 109 Gene3D G3DSA:3.30.70.100 1 107 2.6E-12 T 15-10-2018 C2I28_10845 2b7963a3e103df4bfa66f8ef3669c4d0 109 SUPERFAMILY SSF54909 1 102 3.89E-12 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_10845 2b7963a3e103df4bfa66f8ef3669c4d0 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 72 1.8E-9 T 15-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I28_25790 79be80eceecd243d0f00c90ad58d24e7 97 SUPERFAMILY SSF47789 43 96 2.75E-10 T 15-10-2018 C2I28_25790 79be80eceecd243d0f00c90ad58d24e7 97 Gene3D G3DSA:1.10.150.20 40 97 8.1E-12 T 15-10-2018 C2I28_25790 79be80eceecd243d0f00c90ad58d24e7 97 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 43 90 1.5E-5 T 15-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 Gene3D G3DSA:3.40.50.300 12 289 3.0E-111 T 15-10-2018 C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 SUPERFAMILY SSF52540 7 231 1.1E-9 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 Gene3D G3DSA:1.10.20.140 115 187 3.0E-111 T 15-10-2018 C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 Pfam PF01715 IPP transferase 41 285 1.8E-87 T 15-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 292 3.4E-117 T 15-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 302 31.907 T 15-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 C2I28_02095 eff37d35c05ed243813b4176bb6c787a 316 SUPERFAMILY SSF52540 8 156 1.8E-22 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12160 407c73d575c86785e353643c4e7db8b8 550 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 10 550 6.3E-296 T 15-10-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 C2I28_12160 407c73d575c86785e353643c4e7db8b8 550 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 11 550 1.1E-285 T 15-10-2018 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 C2I28_12160 407c73d575c86785e353643c4e7db8b8 550 SUPERFAMILY SSF100950 227 496 7.44E-22 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_12160 407c73d575c86785e353643c4e7db8b8 550 Gene3D G3DSA:3.40.1080.10 38 243 4.4E-17 T 15-10-2018 C2I28_12160 407c73d575c86785e353643c4e7db8b8 550 SUPERFAMILY SSF100950 41 278 1.95E-30 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_10920 5b9fcbb7eb7656329a0981b0a5dd1307 269 SUPERFAMILY SSF53613 4 264 9.2E-86 T 15-10-2018 IPR029056 Ribokinase-like C2I28_10920 5b9fcbb7eb7656329a0981b0a5dd1307 269 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 259 1.7E-105 T 15-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 C2I28_10920 5b9fcbb7eb7656329a0981b0a5dd1307 269 Pfam PF08543 Phosphomethylpyrimidine kinase 13 257 1.7E-97 T 15-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 C2I28_10920 5b9fcbb7eb7656329a0981b0a5dd1307 269 Gene3D G3DSA:3.40.1190.20 1 267 2.2E-105 T 15-10-2018 IPR029056 Ribokinase-like C2I28_17145 81b23ca778ec530de5e23b3e9f084d5f 437 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 249 412 4.3E-29 T 15-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain C2I28_17145 81b23ca778ec530de5e23b3e9f084d5f 437 Pfam PF07005 Putative sugar-binding N-terminal domain 3 225 1.2E-56 T 15-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain C2I28_17145 81b23ca778ec530de5e23b3e9f084d5f 437 Gene3D G3DSA:3.40.980.20 236 425 1.4E-27 T 15-10-2018 C2I28_17145 81b23ca778ec530de5e23b3e9f084d5f 437 Gene3D G3DSA:3.40.50.10840 3 231 2.0E-65 T 15-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily C2I28_17145 81b23ca778ec530de5e23b3e9f084d5f 437 SUPERFAMILY SSF142764 4 420 1.96E-94 T 15-10-2018 C2I28_10045 1672cd4fd318911928ae2c80594d9300 186 SUPERFAMILY SSF55729 2 136 2.04E-21 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_10045 1672cd4fd318911928ae2c80594d9300 186 Pfam PF13302 Acetyltransferase (GNAT) domain 7 132 5.6E-13 T 15-10-2018 IPR000182 GNAT domain C2I28_10045 1672cd4fd318911928ae2c80594d9300 186 Gene3D G3DSA:3.40.630.30 1 168 6.1E-22 T 15-10-2018 C2I28_15760 5fcf5196c4221aa49f63f04953a57802 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 5.9E-24 T 15-10-2018 C2I28_15760 5fcf5196c4221aa49f63f04953a57802 238 SUPERFAMILY SSF56784 4 227 6.53E-43 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_15760 5fcf5196c4221aa49f63f04953a57802 238 Gene3D G3DSA:3.40.50.1000 6 223 9.0E-79 T 15-10-2018 IPR023214 HAD superfamily C2I28_15760 5fcf5196c4221aa49f63f04953a57802 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 194 3.8E-14 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_15760 5fcf5196c4221aa49f63f04953a57802 238 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 226 4.6E-84 T 15-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 C2I28_15760 5fcf5196c4221aa49f63f04953a57802 238 Gene3D G3DSA:1.10.150.240 17 100 9.0E-79 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 SUPERFAMILY SSF51735 114 272 1.75E-53 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 SUPERFAMILY SSF50129 1 147 9.43E-40 T 15-10-2018 IPR011032 GroES-like superfamily C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 Pfam PF00107 Zinc-binding dehydrogenase 154 275 4.7E-39 T 15-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 Gene3D G3DSA:3.40.50.720 123 295 6.8E-107 T 15-10-2018 C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 Gene3D G3DSA:3.90.180.10 8 323 6.8E-107 T 15-10-2018 C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 9.9E-13 T 15-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 C2I28_19885 2719c675ffe37cc78ced061d5fd7641c 327 SMART SM00829 10 325 8.4E-52 T 15-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 C2I28_17115 a89d34fbca9b1244e3f227cfe183e173 51 Gene3D G3DSA:1.20.58.990 3 50 2.5E-8 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_17115 a89d34fbca9b1244e3f227cfe183e173 51 SUPERFAMILY SSF140500 6 48 1.28E-11 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_17115 a89d34fbca9b1244e3f227cfe183e173 51 Pfam PF09388 Spo0E like sporulation regulatory protein 8 47 5.8E-11 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 Pfam PF11563 Protoglobin 29 182 2.2E-38 T 15-10-2018 C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 SMART SM00283 193 426 1.4E-20 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 SUPERFAMILY SSF58104 196 425 1.1E-49 T 15-10-2018 C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 262 425 1.1E-33 T 15-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 Gene3D G3DSA:1.10.490.10 18 174 7.6E-39 T 15-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 SUPERFAMILY SSF46458 20 173 3.45E-31 T 15-10-2018 IPR009050 Globin-like superfamily C2I28_01020 a23a9da24c89ed37bbef2fb0df1d4fd7 429 Gene3D G3DSA:1.10.287.950 205 429 5.2E-44 T 15-10-2018 C2I28_17815 79ea47429df03f8fa7307f64c5816df2 204 SUPERFAMILY SSF53254 7 172 2.36E-36 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_17815 79ea47429df03f8fa7307f64c5816df2 204 Gene3D G3DSA:3.40.50.1240 5 201 9.0E-41 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_17815 79ea47429df03f8fa7307f64c5816df2 204 SMART SM00855 6 154 1.4E-15 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_17815 79ea47429df03f8fa7307f64c5816df2 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 161 1.0E-32 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_17815 79ea47429df03f8fa7307f64c5816df2 204 PIRSF PIRSF000709 5 164 0.0051 T 15-10-2018 C2I28_01965 7933794db120ef7ed286c3b04e598f01 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 7.8E-62 T 15-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 C2I28_23085 3683f8f199897aea875d4a59245ef2f9 210 Pfam PF07875 Coat F domain 118 180 3.0E-14 T 15-10-2018 IPR012851 Spore coat protein CotF-like C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 SUPERFAMILY SSF100950 73 231 1.19E-22 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 Gene3D G3DSA:1.10.10.10 1 53 1.3E-7 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.0E-9 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.0E-9 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 3.1E-15 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 SMART SM01134 71 232 1.3E-47 T 15-10-2018 C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 Pfam PF00455 DeoR C terminal sensor domain 76 230 9.3E-37 T 15-10-2018 IPR014036 DeoR C-terminal sensor domain C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 15-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 SMART SM00420 6 58 5.6E-13 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_25475 bf9a355f05a6cf3b2c8272ccf18451d4 252 SUPERFAMILY SSF46785 4 61 4.23E-12 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21265 96d06f16807b0a5822aeaecce932bb49 150 Pfam PF07849 Protein of unknown function (DUF1641) 115 133 6.2E-5 T 15-10-2018 IPR012440 Protein of unknown function DUF1641 C2I28_22360 f1e0ce7420ba8dcd48c320be3088e805 313 Gene3D G3DSA:1.10.3720.10 87 301 2.0E-28 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_22360 f1e0ce7420ba8dcd48c320be3088e805 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 304 5.3E-42 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_22360 f1e0ce7420ba8dcd48c320be3088e805 313 SUPERFAMILY SSF161098 93 291 1.96E-22 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18325 87739129227d3a4925ec168464992da0 199 Gene3D G3DSA:3.90.640.20 108 194 6.0E-18 T 15-10-2018 IPR037126 PdaC/RsiV-like superfamily C2I28_18325 87739129227d3a4925ec168464992da0 199 Pfam PF13739 Domain of unknown function (DUF4163) 18 92 8.0E-10 T 15-10-2018 IPR025303 Deacetylase PdaC C2I28_18325 87739129227d3a4925ec168464992da0 199 Pfam PF11738 Protein of unknown function (DUF3298) 110 180 1.4E-16 T 15-10-2018 IPR021729 Domain of unknown function DUF3298 C2I28_18325 87739129227d3a4925ec168464992da0 199 Gene3D G3DSA:3.30.565.40 6 106 2.9E-13 T 15-10-2018 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 SMART SM00240 26 79 1.3E-6 T 15-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 SMART SM00862 140 218 8.2E-10 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 Pfam PF00498 FHA domain 27 95 4.4E-15 T 15-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 142 217 2.0E-14 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 Gene3D G3DSA:2.60.200.20 4 106 9.5E-20 T 15-10-2018 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 SUPERFAMILY SSF49879 15 101 1.82E-19 T 15-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 SUPERFAMILY SSF46894 127 219 1.08E-12 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_23350 0715fc53feb850a12a50b1ad2ef5deca 226 Gene3D G3DSA:1.10.10.10 121 225 1.4E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06730 11b2a6702a7a37b2a4be1334424c599e 175 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 9 160 1.3E-29 T 15-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 C2I28_06730 11b2a6702a7a37b2a4be1334424c599e 175 SUPERFAMILY SSF52540 8 143 6.33E-19 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06730 11b2a6702a7a37b2a4be1334424c599e 175 Gene3D G3DSA:3.40.50.300 8 174 2.7E-50 T 15-10-2018 C2I28_06730 11b2a6702a7a37b2a4be1334424c599e 175 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 9 140 2.0E-30 T 15-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 C2I28_04660 c44ef781529482dd69a09507437f2604 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 291 2.7E-25 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_04660 c44ef781529482dd69a09507437f2604 295 Gene3D G3DSA:1.10.3720.10 71 293 7.2E-35 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_04660 c44ef781529482dd69a09507437f2604 295 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 14 291 1.6E-82 T 15-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 C2I28_04660 c44ef781529482dd69a09507437f2604 295 SUPERFAMILY SSF161098 33 285 3.36E-37 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_02490 dd221456a7363df30b46cebffb9346de 271 Pfam PF00460 Flagella basal body rod protein 5 35 2.2E-12 T 15-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I28_02490 dd221456a7363df30b46cebffb9346de 271 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 250 5.3E-54 T 15-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 C2I28_02490 dd221456a7363df30b46cebffb9346de 271 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 15-10-2018 IPR019776 Flagellar basal body rod protein, conserved site C2I28_02490 dd221456a7363df30b46cebffb9346de 271 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 152 252 3.9E-26 T 15-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G C2I28_02490 dd221456a7363df30b46cebffb9346de 271 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 139 1.9E-44 T 15-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G C2I28_02490 dd221456a7363df30b46cebffb9346de 271 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 189 269 2.5E-23 T 15-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I28_02490 dd221456a7363df30b46cebffb9346de 271 SUPERFAMILY SSF117143 91 231 1.57E-31 T 15-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like C2I28_23940 7c9f2c6c06f49e914b6fec8003491352 440 Gene3D G3DSA:3.30.950.30 27 161 2.1E-19 T 15-10-2018 IPR038461 Schlafen, AAA domain superfamily C2I28_23940 7c9f2c6c06f49e914b6fec8003491352 440 Pfam PF04326 Putative DNA-binding domain 38 152 6.9E-13 T 15-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 C2I28_25335 c5da140a5ac76967d391c98db481efdc 240 Gene3D G3DSA:2.60.120.40 93 233 4.4E-8 T 15-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I28_25335 c5da140a5ac76967d391c98db481efdc 240 SUPERFAMILY SSF49842 96 231 1.19E-16 T 15-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 SUPERFAMILY SSF90002 218 298 1.29E-12 T 15-10-2018 C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 SUPERFAMILY SSF52540 2 182 2.42E-27 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 SMART SM00833 217 302 1.5E-11 T 15-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 Gene3D G3DSA:3.30.1220.10 199 303 7.6E-10 T 15-10-2018 IPR036627 CobW-like, C-terminal domain superfamily C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 181 3.8E-44 T 15-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 218 299 9.3E-16 T 15-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal C2I28_17840 ef2f0f459da31baacf798576ccd6b3b7 306 Gene3D G3DSA:3.40.50.300 1 198 1.2E-51 T 15-10-2018 C2I28_09710 3ac3e9e36ffeb0fbb138cd557c103649 265 Pfam PF03824 High-affinity nickel-transport protein 5 192 6.4E-7 T 15-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 C2I28_27400 ce87b932b85d25234444d13b50af1e2a 186 Pfam PF07552 Spore Coat Protein X and V domain 65 121 8.7E-22 T 15-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I28_27400 ce87b932b85d25234444d13b50af1e2a 186 Pfam PF07552 Spore Coat Protein X and V domain 130 185 1.4E-21 T 15-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 Pfam PF00270 DEAD/DEAH box helicase 28 196 3.4E-44 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 Gene3D G3DSA:3.40.50.300 220 439 1.5E-43 T 15-10-2018 C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 SUPERFAMILY SSF52540 72 359 7.16E-64 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 SMART SM00490 260 341 1.8E-29 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 438 49.427 T 15-10-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 Pfam PF00271 Helicase conserved C-terminal domain 233 341 8.2E-27 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 Gene3D G3DSA:3.40.50.300 2 219 7.3E-68 T 15-10-2018 C2I28_04225 70ed6c3ca09c5db43e4d954b3a66566d 439 SMART SM00487 23 224 2.8E-53 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_17540 3946940fa7a6a4e9fdc3fa5725f74dc2 188 Gene3D G3DSA:1.10.101.10 39 119 1.6E-24 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_17540 3946940fa7a6a4e9fdc3fa5725f74dc2 188 SUPERFAMILY SSF47090 45 111 2.62E-19 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_17540 3946940fa7a6a4e9fdc3fa5725f74dc2 188 Pfam PF01471 Putative peptidoglycan binding domain 58 109 7.2E-15 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_04020 bff6aa9d10e905f64b6b2836cab8cf36 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 21 5.8E-5 T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_04020 bff6aa9d10e905f64b6b2836cab8cf36 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 21 1.3E-5 T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_04020 bff6aa9d10e905f64b6b2836cab8cf36 145 SUPERFAMILY SSF54523 9 110 5.26E-5 T 15-10-2018 C2I28_04020 bff6aa9d10e905f64b6b2836cab8cf36 145 PIRSF PIRSF021292 3 145 5.2E-38 T 15-10-2018 IPR016785 ComG operon protein 4 GO:0030420 C2I28_17525 9ef23ddabec0afc62e2e722c8f40471c 431 Gene3D G3DSA:1.20.1250.20 6 200 7.6E-44 T 15-10-2018 C2I28_17525 9ef23ddabec0afc62e2e722c8f40471c 431 Pfam PF07690 Major Facilitator Superfamily 22 384 1.1E-60 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_17525 9ef23ddabec0afc62e2e722c8f40471c 431 SUPERFAMILY SSF103473 5 425 1.57E-86 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_17525 9ef23ddabec0afc62e2e722c8f40471c 431 Gene3D G3DSA:1.20.1250.20 224 425 4.0E-31 T 15-10-2018 C2I28_17525 9ef23ddabec0afc62e2e722c8f40471c 431 PIRSF PIRSF002808 2 431 3.0E-34 T 15-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 C2I28_20465 c02c24d5d0fbe86a12d93c5ec36a002e 79 Gene3D G3DSA:1.10.1740.10 2 76 5.3E-15 T 15-10-2018 C2I28_20465 c02c24d5d0fbe86a12d93c5ec36a002e 79 Pfam PF04542 Sigma-70 region 2 14 74 3.0E-10 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_20465 c02c24d5d0fbe86a12d93c5ec36a002e 79 SUPERFAMILY SSF88946 14 75 1.18E-12 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_18880 329a4a2e3cd34ef506f31638b2a5dca2 199 Pfam PF02397 Bacterial sugar transferase 2 176 2.8E-64 T 15-10-2018 IPR003362 Bacterial sugar transferase C2I28_05135 7e3d86b58378492c28e333ecbb869d65 265 Gene3D G3DSA:3.40.50.300 20 263 3.3E-62 T 15-10-2018 C2I28_05135 7e3d86b58378492c28e333ecbb869d65 265 Pfam PF00005 ABC transporter 40 176 7.7E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_05135 7e3d86b58378492c28e333ecbb869d65 265 SMART SM00382 49 227 6.4E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_05135 7e3d86b58378492c28e333ecbb869d65 265 SUPERFAMILY SSF52540 23 251 1.6E-66 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05135 7e3d86b58378492c28e333ecbb869d65 265 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_24920 87ac85f9a8660cad0e2cb94fadde4143 291 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 20 222 5.5E-48 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_24920 87ac85f9a8660cad0e2cb94fadde4143 291 Gene3D G3DSA:3.30.70.120 200 274 6.3E-16 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_24920 87ac85f9a8660cad0e2cb94fadde4143 291 PIRSF PIRSF006483 1 290 1.3E-77 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_24920 87ac85f9a8660cad0e2cb94fadde4143 291 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 228 282 4.0E-20 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_16195 4fe2b351f2ce074d17c7428dec44c0e0 443 SUPERFAMILY SSF103473 7 426 3.66E-83 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_16195 4fe2b351f2ce074d17c7428dec44c0e0 443 Pfam PF07690 Major Facilitator Superfamily 22 389 3.5E-44 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_16195 4fe2b351f2ce074d17c7428dec44c0e0 443 Gene3D G3DSA:1.20.1250.20 2 433 6.0E-80 T 15-10-2018 C2I28_00900 50a8909f05602cfeb030c9fc65ab38a5 121 Pfam PF11518 Protein of unknown function (DUF3221) 15 118 7.9E-8 T 15-10-2018 IPR021598 Protein of unknown function DUF3221 C2I28_25245 ea6f9e3d5102956c299630b27c15f8ee 203 Gene3D G3DSA:3.30.240.20 74 148 2.2E-20 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_25245 ea6f9e3d5102956c299630b27c15f8ee 203 Pfam PF04239 Protein of unknown function (DUF421) 82 192 2.8E-26 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_00325 dad6175b0e806ee346f5b09574f91b08 109 SUPERFAMILY SSF46785 10 100 1.47E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00325 dad6175b0e806ee346f5b09574f91b08 109 Gene3D G3DSA:1.10.10.10 1 108 2.5E-35 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00325 dad6175b0e806ee346f5b09574f91b08 109 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 1.9E-21 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_03605 f4798f10706baa29bdac6c3a8b1f0d35 298 SUPERFAMILY SSF51569 3 290 3.37E-70 T 15-10-2018 C2I28_03605 f4798f10706baa29bdac6c3a8b1f0d35 298 Gene3D G3DSA:3.20.20.70 1 298 9.3E-116 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_03605 f4798f10706baa29bdac6c3a8b1f0d35 298 Pfam PF00682 HMGL-like 6 279 2.9E-51 T 15-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 Gene3D G3DSA:1.20.120.530 84 221 4.3E-15 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 52 71 2.7E-6 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 41 52 2.7E-6 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 SUPERFAMILY SSF46785 12 85 2.43E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 81 1.8E-21 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 SMART SM00345 23 81 4.7E-19 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 SUPERFAMILY SSF48008 87 215 5.23E-14 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 1.3E-8 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 1.3E-8 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 Gene3D G3DSA:1.10.10.10 15 82 4.1E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 SMART SM00895 91 214 6.1E-5 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_01150 580dffc155d00e6ddcc843621131a4f6 226 Pfam PF07729 FCD domain 95 209 3.6E-16 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_10280 2d94a43c8daef2ae2541c398c35e5401 206 Pfam PF13411 MerR HTH family regulatory protein 12 75 1.2E-5 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_10280 2d94a43c8daef2ae2541c398c35e5401 206 Gene3D G3DSA:1.10.1660.10 1 149 2.4E-10 T 15-10-2018 C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 9 33 - T 15-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 Gene3D G3DSA:3.30.1330.30 1 81 3.7E-23 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 81 5.2E-15 T 15-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 SUPERFAMILY SSF55315 5 81 2.95E-20 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 PRINTS PR00884 Ribosomal protein HS6 signature 20 30 2.5E-6 T 15-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 PRINTS PR00884 Ribosomal protein HS6 signature 30 41 2.5E-6 T 15-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 PRINTS PR00884 Ribosomal protein HS6 signature 56 66 2.5E-6 T 15-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08655 3dbf58e9dc947b537fcd34c36eaee69d 82 PRINTS PR00884 Ribosomal protein HS6 signature 70 82 2.5E-6 T 15-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 Pfam PF00206 Lyase 16 345 2.1E-113 T 15-10-2018 IPR022761 Fumarate lyase, N-terminal C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 15-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 1.8E-6 T 15-10-2018 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 1.8E-6 T 15-10-2018 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 9 470 3.0E-237 T 15-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 SUPERFAMILY SSF48557 8 463 8.17E-149 T 15-10-2018 IPR008948 L-Aspartase-like GO:0003824 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 Pfam PF10415 Fumarase C C-terminus 411 464 7.0E-17 T 15-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 Gene3D G3DSA:1.10.40.30 411 462 5.6E-19 T 15-10-2018 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 Gene3D G3DSA:1.20.200.10 143 410 3.5E-116 T 15-10-2018 C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 Gene3D G3DSA:1.10.275.10 9 142 3.0E-57 T 15-10-2018 IPR024083 Fumarase/histidase, N-terminal C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 1.5E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 1.5E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 1.5E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_23485 618af4f408f08d4fcc404f0b0e4c16d4 476 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 1.5E-32 T 15-10-2018 IPR000362 Fumarate lyase family C2I28_07175 92b13c7c523c409220a2d49cd032b599 143 Gene3D G3DSA:1.20.120.340 4 119 2.4E-25 T 15-10-2018 C2I28_07175 92b13c7c523c409220a2d49cd032b599 143 TIGRFAM TIGR00208 fliS: flagellar protein FliS 12 117 1.9E-19 T 15-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I28_07175 92b13c7c523c409220a2d49cd032b599 143 PIRSF PIRSF039090 5 125 1.9E-26 T 15-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I28_07175 92b13c7c523c409220a2d49cd032b599 143 Pfam PF02561 Flagellar protein FliS 12 115 5.8E-25 T 15-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I28_07175 92b13c7c523c409220a2d49cd032b599 143 SUPERFAMILY SSF101116 9 119 3.01E-27 T 15-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 C2I28_09520 ed3f1a7da9f55e47334991f51104e75f 397 PIRSF PIRSF012509 1 396 8.9E-151 T 15-10-2018 IPR011426 CamS sex pheromone cAM373 C2I28_09520 ed3f1a7da9f55e47334991f51104e75f 397 Gene3D G3DSA:3.10.570.10 53 397 9.9E-132 T 15-10-2018 C2I28_09520 ed3f1a7da9f55e47334991f51104e75f 397 Pfam PF07537 CamS sex pheromone cAM373 precursor 57 388 2.6E-123 T 15-10-2018 IPR011426 CamS sex pheromone cAM373 C2I28_22490 c91d59500e1e2bd4ba692afd65b13a8e 441 Gene3D G3DSA:3.30.465.40 5 227 2.2E-52 T 15-10-2018 C2I28_22490 c91d59500e1e2bd4ba692afd65b13a8e 441 SUPERFAMILY SSF56176 31 209 2.29E-47 T 15-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 C2I28_22490 c91d59500e1e2bd4ba692afd65b13a8e 441 SUPERFAMILY SSF55103 214 437 3.76E-14 T 15-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 C2I28_22490 c91d59500e1e2bd4ba692afd65b13a8e 441 Pfam PF01565 FAD binding domain 36 170 4.1E-32 T 15-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 C2I28_00280 77e957acf890e56fbc1f594dbe1838f3 273 Pfam PF13649 Methyltransferase domain 47 138 5.7E-20 T 15-10-2018 C2I28_00280 77e957acf890e56fbc1f594dbe1838f3 273 Gene3D G3DSA:3.40.50.150 3 233 7.0E-43 T 15-10-2018 C2I28_00280 77e957acf890e56fbc1f594dbe1838f3 273 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 10 271 1.1E-65 T 15-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 C2I28_00280 77e957acf890e56fbc1f594dbe1838f3 273 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 2 271 28.469 T 15-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 C2I28_00280 77e957acf890e56fbc1f594dbe1838f3 273 SUPERFAMILY SSF53335 10 189 2.13E-39 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_23555 948878dabb38bbfbe168a09fbe49a798 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 2.5E-10 T 15-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I28_23555 948878dabb38bbfbe168a09fbe49a798 101 SUPERFAMILY SSF54909 1 89 2.4E-16 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_23555 948878dabb38bbfbe168a09fbe49a798 101 Gene3D G3DSA:3.30.70.100 1 101 3.7E-20 T 15-10-2018 C2I28_04320 e069eb5a847534ab1f9a222f6447946e 324 SMART SM00322 4 68 3.1E-5 T 15-10-2018 IPR004087 K Homology domain GO:0003676 C2I28_04320 e069eb5a847534ab1f9a222f6447946e 324 SUPERFAMILY SSF54791 21 68 3.64E-5 T 15-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 C2I28_04320 e069eb5a847534ab1f9a222f6447946e 324 Gene3D G3DSA:3.40.50.300 109 316 9.7E-77 T 15-10-2018 C2I28_04320 e069eb5a847534ab1f9a222f6447946e 324 Pfam PF02562 PhoH-like protein 113 316 6.6E-98 T 15-10-2018 IPR003714 PhoH-like protein GO:0005524 C2I28_04320 e069eb5a847534ab1f9a222f6447946e 324 SUPERFAMILY SSF52540 54 291 1.52E-40 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_20540 3c7d005c501a611234a06fe86d722b40 173 SUPERFAMILY SSF81301 11 171 5.56E-46 T 15-10-2018 C2I28_20540 3c7d005c501a611234a06fe86d722b40 173 Gene3D G3DSA:3.30.460.10 6 173 9.3E-49 T 15-10-2018 C2I28_20540 3c7d005c501a611234a06fe86d722b40 173 Pfam PF04229 GrpB protein 9 168 2.9E-44 T 15-10-2018 IPR007344 GrpB/Dephospho-CoA kinase C2I28_16205 4c25017b26695110d66f8d5522c2c176 154 Gene3D G3DSA:3.40.1400.10 1 152 1.9E-59 T 15-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_16205 4c25017b26695110d66f8d5522c2c176 154 PIRSF PIRSF005384 1 147 2.9E-57 T 15-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_16205 4c25017b26695110d66f8d5522c2c176 154 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.9E-60 T 15-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_16205 4c25017b26695110d66f8d5522c2c176 154 SUPERFAMILY SSF89623 1 144 6.67E-57 T 15-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_16205 4c25017b26695110d66f8d5522c2c176 154 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 1.4E-51 T 15-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 C2I28_16205 4c25017b26695110d66f8d5522c2c176 154 Pfam PF02502 Ribose/Galactose Isomerase 3 140 2.6E-56 T 15-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 C2I28_22955 561be85854a2684151ce4f7539582295 108 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.711 T 15-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22955 561be85854a2684151ce4f7539582295 108 SUPERFAMILY SSF51278 1 105 8.11E-46 T 15-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22955 561be85854a2684151ce4f7539582295 108 Gene3D G3DSA:2.10.150.10 1 108 2.3E-47 T 15-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22955 561be85854a2684151ce4f7539582295 108 Pfam PF00699 Urease beta subunit 3 98 6.0E-43 T 15-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_22955 561be85854a2684151ce4f7539582295 108 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 101 1.7E-43 T 15-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 SUPERFAMILY SSF48179 270 479 2.35E-40 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 203 454 8.4E-53 T 15-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 17 171 9.9E-20 T 15-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 SUPERFAMILY SSF51735 12 265 5.12E-65 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 Gene3D G3DSA:1.10.1040.10 269 481 4.5E-54 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 Gene3D G3DSA:3.40.50.720 3 265 3.3E-51 T 15-10-2018 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 PRINTS PR00084 Mannitol dehydrogenase signature 204 217 2.8E-6 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 PRINTS PR00084 Mannitol dehydrogenase signature 163 176 2.8E-6 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 PRINTS PR00084 Mannitol dehydrogenase signature 18 28 2.8E-6 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_17445 9f0b9d92c1b88420c2fcdee80986302c 487 PRINTS PR00084 Mannitol dehydrogenase signature 232 247 2.8E-6 T 15-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 C2I28_07460 3f277ababfb9a186052b735bafd9a3d7 176 Gene3D G3DSA:3.40.50.10490 1 176 9.7E-59 T 15-10-2018 C2I28_07460 3f277ababfb9a186052b735bafd9a3d7 176 SUPERFAMILY SSF53697 3 156 3.65E-5 T 15-10-2018 C2I28_07460 3f277ababfb9a186052b735bafd9a3d7 176 Pfam PF10740 Domain of unknown function (DUF2529) 1 172 1.0E-62 T 15-10-2018 IPR019676 Domain of unknown function (DUF2529) C2I28_18810 88004ba370c959fc57ced957409dcaec 156 Gene3D G3DSA:1.20.120.450 2 145 4.5E-36 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_18810 88004ba370c959fc57ced957409dcaec 156 SUPERFAMILY SSF109854 1 143 1.04E-20 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_13655 6aefc2dfe647d1171069830ff8184d92 255 SUPERFAMILY SSF89550 1 205 1.88E-16 T 15-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I28_13655 6aefc2dfe647d1171069830ff8184d92 255 PIRSF PIRSF016557 1 255 3.3E-106 T 15-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 C2I28_13655 6aefc2dfe647d1171069830ff8184d92 255 Gene3D G3DSA:3.20.20.140 1 255 3.2E-96 T 15-10-2018 C2I28_17800 24cf009ed310862a044e7097d30aec04 359 Gene3D G3DSA:3.90.1150.10 26 352 2.0E-108 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_17800 24cf009ed310862a044e7097d30aec04 359 Pfam PF00155 Aminotransferase class I and II 50 352 1.0E-49 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_17800 24cf009ed310862a044e7097d30aec04 359 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 212 225 - T 15-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 C2I28_17800 24cf009ed310862a044e7097d30aec04 359 Gene3D G3DSA:3.40.640.10 37 260 2.0E-108 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_17800 24cf009ed310862a044e7097d30aec04 359 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 6 352 9.1E-91 T 15-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 C2I28_17800 24cf009ed310862a044e7097d30aec04 359 SUPERFAMILY SSF53383 22 354 7.85E-81 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_11885 78fdcdced591448aee969f13969fd661 245 Gene3D G3DSA:3.30.2010.10 44 135 3.4E-9 T 15-10-2018 C2I28_11885 78fdcdced591448aee969f13969fd661 245 Pfam PF01435 Peptidase family M48 141 224 3.8E-7 T 15-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 C2I28_11885 78fdcdced591448aee969f13969fd661 245 Pfam PF01435 Peptidase family M48 57 133 3.6E-12 T 15-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 C2I28_12475 0806ec36e3ce9e7142787d85089e3998 257 Gene3D G3DSA:3.40.50.150 27 257 1.4E-65 T 15-10-2018 C2I28_12475 0806ec36e3ce9e7142787d85089e3998 257 Pfam PF08241 Methyltransferase domain 46 141 1.9E-25 T 15-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 C2I28_12475 0806ec36e3ce9e7142787d85089e3998 257 SUPERFAMILY SSF53335 30 255 5.73E-45 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_10385 c2c47ec58392ee05f18e9fe3d4c335f9 162 Pfam PF04892 VanZ like family 28 148 1.1E-22 T 15-10-2018 IPR006976 VanZ-like C2I28_01540 fb459f3da3ebbe36d6656803b9b1dc0d 225 Pfam PF00877 NlpC/P60 family 121 223 7.1E-32 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_01540 fb459f3da3ebbe36d6656803b9b1dc0d 225 SUPERFAMILY SSF54001 106 225 2.65E-40 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_01540 fb459f3da3ebbe36d6656803b9b1dc0d 225 Gene3D G3DSA:1.10.101.10 27 95 7.1E-22 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_01540 fb459f3da3ebbe36d6656803b9b1dc0d 225 Gene3D G3DSA:3.90.1720.10 101 225 9.3E-42 T 15-10-2018 C2I28_01540 fb459f3da3ebbe36d6656803b9b1dc0d 225 Pfam PF01471 Putative peptidoglycan binding domain 37 92 9.6E-18 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_01540 fb459f3da3ebbe36d6656803b9b1dc0d 225 SUPERFAMILY SSF47090 28 95 5.3E-21 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.3E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.3E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 1.3E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.3E-13 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 SUPERFAMILY SSF51735 13 261 1.57E-53 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 Pfam PF00106 short chain dehydrogenase 16 216 5.4E-30 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_15570 0a17413c621bdbdfc178a81d40abf8b0 306 Gene3D G3DSA:3.40.50.720 1 304 5.7E-85 T 15-10-2018 C2I28_08370 387b1ebf752c8662775169776292f2db 185 Gene3D G3DSA:3.40.50.1470 1 185 1.3E-73 T 15-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 C2I28_08370 387b1ebf752c8662775169776292f2db 185 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 38.135 T 15-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 C2I28_08370 387b1ebf752c8662775169776292f2db 185 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 15-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 C2I28_08370 387b1ebf752c8662775169776292f2db 185 SUPERFAMILY SSF53178 2 185 7.59E-72 T 15-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 C2I28_08370 387b1ebf752c8662775169776292f2db 185 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 15-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 C2I28_08370 387b1ebf752c8662775169776292f2db 185 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 185 1.9E-72 T 15-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 C2I28_08370 387b1ebf752c8662775169776292f2db 185 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 4.0E-62 T 15-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 C2I28_22145 7d35ac0c450f150530df5ba0c1b5fa8b 290 Pfam PF01435 Peptidase family M48 87 289 6.4E-37 T 15-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 C2I28_22145 7d35ac0c450f150530df5ba0c1b5fa8b 290 Gene3D G3DSA:3.30.2010.10 71 165 5.6E-28 T 15-10-2018 C2I28_11125 36d4eef2f83e50bdb584de01833cd0f4 239 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 9 234 1.0E-51 T 15-10-2018 C2I28_11125 36d4eef2f83e50bdb584de01833cd0f4 239 Pfam PF12787 EcsC protein family 7 234 1.5E-75 T 15-10-2018 IPR024787 EcsC protein C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 208 218 - T 15-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 SUPERFAMILY SSF52743 147 414 1.28E-84 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 204 217 1.7E-20 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 359 375 1.7E-20 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 185 1.7E-20 T 15-10-2018 IPR015500 Peptidase S8, subtilisin-related C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 Gene3D G3DSA:3.40.50.200 138 415 3.5E-96 T 15-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 Pfam PF00082 Subtilase family 168 393 1.1E-40 T 15-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 360 370 - T 15-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site C2I28_27500 08e6c34a47cfa9c93c78d6680e195481 415 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 171 182 - T 15-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site C2I28_15750 09634e0dfae744cc3fa27f434ecb8027 457 Gene3D G3DSA:1.20.1740.10 20 457 4.4E-125 T 15-10-2018 C2I28_15750 09634e0dfae744cc3fa27f434ecb8027 457 Pfam PF13520 Amino acid permease 26 432 3.2E-62 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_15750 09634e0dfae744cc3fa27f434ecb8027 457 PIRSF PIRSF006060 6 457 3.1E-91 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_21990 aee3a8a34390b0d4781e22d2f3e6bac9 297 Pfam PF00561 alpha/beta hydrolase fold 33 143 8.2E-8 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_21990 aee3a8a34390b0d4781e22d2f3e6bac9 297 Gene3D G3DSA:3.40.50.1820 15 290 1.4E-43 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_21990 aee3a8a34390b0d4781e22d2f3e6bac9 297 SUPERFAMILY SSF53474 6 287 8.19E-24 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_04745 9efc1a8259fb49fe27d7d8e810898ffc 87 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 42 2.5E-14 T 15-10-2018 IPR003849 Preprotein translocase YajC C2I28_04745 9efc1a8259fb49fe27d7d8e810898ffc 87 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 2.5E-14 T 15-10-2018 IPR003849 Preprotein translocase YajC C2I28_04745 9efc1a8259fb49fe27d7d8e810898ffc 87 Pfam PF02699 Preprotein translocase subunit 6 81 7.3E-31 T 15-10-2018 IPR003849 Preprotein translocase YajC C2I28_04745 9efc1a8259fb49fe27d7d8e810898ffc 87 SMART SM01323 2 84 1.9E-40 T 15-10-2018 IPR003849 Preprotein translocase YajC C2I28_04745 9efc1a8259fb49fe27d7d8e810898ffc 87 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 83 1.7E-30 T 15-10-2018 IPR003849 Preprotein translocase YajC C2I28_19100 f3c27ee4216197f426cb98b2bc6bb225 525 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 45 514 1.5E-186 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_19100 f3c27ee4216197f426cb98b2bc6bb225 525 PIRSF PIRSF005690 30 525 9.8E-189 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_10330 f29e066e2c1c0944ebada1cbdf2d693b 221 SMART SM00873 62 212 4.3E-7 T 15-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 C2I28_10330 f29e066e2c1c0944ebada1cbdf2d693b 221 Gene3D G3DSA:3.50.40.10 74 201 3.3E-7 T 15-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 C2I28_10330 f29e066e2c1c0944ebada1cbdf2d693b 221 SUPERFAMILY SSF56037 61 218 2.17E-28 T 15-10-2018 C2I28_10330 f29e066e2c1c0944ebada1cbdf2d693b 221 Pfam PF03483 B3/4 domain 64 182 5.3E-16 T 15-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 C2I28_19310 eee9a3fc84c6026cc4af72fb38f20973 521 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 495 2.0E-127 T 15-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 SMART SM00419 163 211 1.3E-11 T 15-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 SMART SM00100 4 124 4.5E-15 T 15-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 Gene3D G3DSA:2.60.120.10 6 139 3.3E-28 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 Pfam PF13545 Crp-like helix-turn-helix domain 146 216 1.2E-13 T 15-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 SUPERFAMILY SSF51206 8 138 3.93E-31 T 15-10-2018 IPR018490 Cyclic nucleotide-binding-like C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 SUPERFAMILY SSF46785 142 228 1.2E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 Gene3D G3DSA:1.10.10.10 140 227 4.8E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 185 200 8.0E-6 T 15-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 169 185 8.0E-6 T 15-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 C2I28_11540 0188bfb94c4a6c804ef4a8d2bedbbf79 232 Pfam PF00027 Cyclic nucleotide-binding domain 24 112 2.9E-18 T 15-10-2018 IPR000595 Cyclic nucleotide-binding domain C2I28_08320 d3b608c4b9902d3fa5999cc371aefd5d 290 PIRSF PIRSF011575 2 290 1.9E-118 T 15-10-2018 IPR008764 Peptidase U57, YabG C2I28_08320 d3b608c4b9902d3fa5999cc371aefd5d 290 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 286 1.5E-134 T 15-10-2018 IPR008764 Peptidase U57, YabG C2I28_08320 d3b608c4b9902d3fa5999cc371aefd5d 290 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 3 280 6.0E-102 T 15-10-2018 IPR008764 Peptidase U57, YabG C2I28_08320 d3b608c4b9902d3fa5999cc371aefd5d 290 Pfam PF05582 YabG peptidase U57 4 285 2.9E-112 T 15-10-2018 IPR008764 Peptidase U57, YabG C2I28_15925 e7d3027564a316b3af503346460a0e67 275 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 7 274 2.3E-104 T 15-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 C2I28_15925 e7d3027564a316b3af503346460a0e67 275 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 5 274 1.3E-140 T 15-10-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 C2I28_19775 2a488808c78a5fbfb1a493892c860071 228 SUPERFAMILY SSF53335 21 224 1.43E-40 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_19775 2a488808c78a5fbfb1a493892c860071 228 Pfam PF01596 O-methyltransferase 30 211 3.2E-43 T 15-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 C2I28_19775 2a488808c78a5fbfb1a493892c860071 228 Gene3D G3DSA:3.40.50.150 8 228 1.1E-76 T 15-10-2018 C2I28_24020 3c72ff678f18b83adaab49adac13ae55 252 Gene3D G3DSA:3.40.50.300 1 247 2.5E-66 T 15-10-2018 C2I28_24020 3c72ff678f18b83adaab49adac13ae55 252 SUPERFAMILY SSF52540 2 226 5.44E-59 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_24020 3c72ff678f18b83adaab49adac13ae55 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_24020 3c72ff678f18b83adaab49adac13ae55 252 Pfam PF00005 ABC transporter 18 164 3.4E-30 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_24020 3c72ff678f18b83adaab49adac13ae55 252 SMART SM00382 26 213 4.3E-11 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 Gene3D G3DSA:3.40.640.10 34 284 2.5E-190 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 Pfam PF00464 Serine hydroxymethyltransferase 6 381 4.2E-181 T 15-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 15-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 SUPERFAMILY SSF53383 4 412 2.72E-183 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 53.506 T 15-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 PIRSF PIRSF000412 1 414 6.6E-171 T 15-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 C2I28_07375 4a4dcec004777b6117aea35fc61951c9 414 Gene3D G3DSA:3.90.1150.10 7 392 2.5E-190 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_09290 49cadcd217be84f5999738d2640c0fd0 156 Gene3D G3DSA:3.40.50.300 5 154 5.9E-44 T 15-10-2018 C2I28_09290 49cadcd217be84f5999738d2640c0fd0 156 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 14 142 3.3E-46 T 15-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 C2I28_09290 49cadcd217be84f5999738d2640c0fd0 156 SUPERFAMILY SSF52540 28 127 9.64E-23 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09290 49cadcd217be84f5999738d2640c0fd0 156 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 12 136 9.3E-41 T 15-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 C2I28_09485 e4466307ef2ee1343ba58c6471863fc7 85 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 2.0E-12 T 15-10-2018 IPR021309 Protein of unknown function DUF2892 C2I28_05790 27ab05740319b89b61bcb3e04c7d7c72 103 SUPERFAMILY SSF52821 3 97 9.56E-29 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_05790 27ab05740319b89b61bcb3e04c7d7c72 103 Pfam PF00581 Rhodanese-like domain 8 97 1.7E-13 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_05790 27ab05740319b89b61bcb3e04c7d7c72 103 Gene3D G3DSA:3.40.250.10 5 101 3.7E-28 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_05790 27ab05740319b89b61bcb3e04c7d7c72 103 SMART SM00450 8 102 2.6E-19 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_26510 53baa331121ba6cb77f18fc16bcb75d7 132 Gene3D G3DSA:2.60.120.10 7 129 1.2E-21 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_26510 53baa331121ba6cb77f18fc16bcb75d7 132 SUPERFAMILY SSF51182 9 120 4.88E-27 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_26510 53baa331121ba6cb77f18fc16bcb75d7 132 Pfam PF07883 Cupin domain 48 115 8.1E-17 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_09815 cd0d94472a4834638024fd3f1003c4e8 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 1.2E-26 T 15-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I28_09815 cd0d94472a4834638024fd3f1003c4e8 97 Pfam PF06013 Proteins of 100 residues with WXG 5 89 2.0E-24 T 15-10-2018 IPR010310 Type VII secretion system ESAT-6-like C2I28_09815 cd0d94472a4834638024fd3f1003c4e8 97 Gene3D G3DSA:1.10.287.1060 1 97 5.3E-27 T 15-10-2018 C2I28_09815 cd0d94472a4834638024fd3f1003c4e8 97 SUPERFAMILY SSF140453 4 96 1.7E-23 T 15-10-2018 IPR036689 ESAT-6-like superfamily C2I28_18120 83aec403b05d71f78b55b711e3ea5c1d 176 Gene3D G3DSA:3.40.50.360 6 166 4.3E-5 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 SUPERFAMILY SSF53623 32 236 5.1E-17 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 Gene3D G3DSA:3.40.1190.10 30 239 5.9E-16 T 15-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 Pfam PF08245 Mur ligase middle domain 37 238 2.6E-9 T 15-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 2 383 1.0E-164 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 258 275 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 77 95 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 196 213 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 34 50 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 293 308 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 111 126 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 140 155 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 362 378 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 162 179 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_13130 e4532dbf7eef65b841cf33bd03701df8 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 57 74 6.2E-88 T 15-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 C2I28_15915 8d3c7933cbeef5d9fe7596cde0693443 164 Gene3D G3DSA:3.40.35.10 1 162 5.0E-57 T 15-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 C2I28_15915 8d3c7933cbeef5d9fe7596cde0693443 164 SUPERFAMILY SSF52728 1 158 2.49E-54 T 15-10-2018 IPR036667 Phosphotransferase system, sorbose subfamily IIB component superfamily GO:0005737|GO:0008982|GO:0009401 C2I28_15915 8d3c7933cbeef5d9fe7596cde0693443 164 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 2 152 5.6E-67 T 15-10-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 C2I28_15915 8d3c7933cbeef5d9fe7596cde0693443 164 Pfam PF03830 PTS system sorbose subfamily IIB component 3 149 1.3E-52 T 15-10-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 Gene3D G3DSA:3.40.710.10 37 306 1.6E-76 T 15-10-2018 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 SUPERFAMILY SSF56601 51 306 6.18E-72 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 ProSitePatterns PS00146 Beta-lactamase class-A active site. 85 100 - T 15-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 Pfam PF13354 Beta-lactamase enzyme family 73 278 9.8E-32 T 15-10-2018 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 123 148 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 83 100 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 185 210 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 238 253 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 221 236 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 159 183 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_24710 950188eac02f6949bce7213d9aeaff55 310 PRINTS PR00118 Beta-lactamase class A signature 52 76 9.5E-63 T 15-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 C2I28_21130 116d78489b94c6884084f4a1fae4015a 166 Pfam PF00583 Acetyltransferase (GNAT) family 42 136 5.8E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_21130 116d78489b94c6884084f4a1fae4015a 166 Gene3D G3DSA:3.40.630.30 2 164 2.0E-31 T 15-10-2018 C2I28_21130 116d78489b94c6884084f4a1fae4015a 166 SUPERFAMILY SSF55729 1 140 2.87E-25 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 SUPERFAMILY SSF46785 7 81 4.28E-26 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 3.3E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 3.3E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 3.3E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 3.3E-19 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 Gene3D G3DSA:1.10.10.10 3 95 5.3E-28 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 5.4E-17 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_16695 bf64455520de3e93bd410a26e6f6faf3 115 SMART SM00418 14 90 1.3E-26 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_00125 0586b133a3136d817067b3f5cda96c22 422 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 239 399 3.4E-9 T 15-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 C2I28_00125 0586b133a3136d817067b3f5cda96c22 422 SUPERFAMILY SSF53756 1 416 2.47E-78 T 15-10-2018 C2I28_00125 0586b133a3136d817067b3f5cda96c22 422 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 65 7.3E-12 T 15-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_00125 0586b133a3136d817067b3f5cda96c22 422 Gene3D G3DSA:3.40.50.2000 2 400 2.2E-81 T 15-10-2018 C2I28_00125 0586b133a3136d817067b3f5cda96c22 422 Gene3D G3DSA:3.40.50.2000 233 399 2.2E-81 T 15-10-2018 C2I28_08120 21dba61edd3ac229da9f66fde372b959 180 Gene3D G3DSA:3.40.50.850 1 178 7.8E-41 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_08120 21dba61edd3ac229da9f66fde372b959 180 Pfam PF00857 Isochorismatase family 6 168 8.8E-28 T 15-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I28_08120 21dba61edd3ac229da9f66fde372b959 180 SUPERFAMILY SSF52499 4 178 1.01E-41 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_06950 3e27426a215897ebf1c7c5e82e2f17bd 277 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 256 4.0E-79 T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_06950 3e27426a215897ebf1c7c5e82e2f17bd 277 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_06950 3e27426a215897ebf1c7c5e82e2f17bd 277 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 266 5.5E-85 T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_06950 3e27426a215897ebf1c7c5e82e2f17bd 277 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 17.889 T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_07695 fa9f56eab11156a68fec4d070ced0165 110 Pfam PF00892 EamA-like transporter family 1 107 2.1E-9 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_07695 fa9f56eab11156a68fec4d070ced0165 110 SUPERFAMILY SSF103481 17 108 6.8E-11 T 15-10-2018 C2I28_03245 8471659a64fa4d2973c0034e269188b0 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 3.4E-266 T 15-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 C2I28_03245 8471659a64fa4d2973c0034e269188b0 492 SUPERFAMILY SSF52540 19 225 3.08E-15 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03245 8471659a64fa4d2973c0034e269188b0 492 Gene3D G3DSA:3.40.50.300 12 236 6.8E-11 T 15-10-2018 C2I28_03245 8471659a64fa4d2973c0034e269188b0 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 3.0E-228 T 15-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 C2I28_03245 8471659a64fa4d2973c0034e269188b0 492 PIRSF PIRSF007466 1 492 2.4E-269 T 15-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 C2I28_04195 2a424274facf60f968e3b361b19fe285 191 SUPERFAMILY SSF56784 3 163 1.63E-17 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_04195 2a424274facf60f968e3b361b19fe285 191 PIRSF PIRSF021362 2 191 9.1E-68 T 15-10-2018 IPR009206 Nucleotidase, putative C2I28_04195 2a424274facf60f968e3b361b19fe285 191 Gene3D G3DSA:3.40.50.1000 2 156 6.3E-8 T 15-10-2018 IPR023214 HAD superfamily C2I28_04195 2a424274facf60f968e3b361b19fe285 191 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 7 182 1.4E-8 T 15-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 C2I28_06315 2c0da56bf4c3e2377cff54f8d1d2aa0e 174 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 159 170 - T 15-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_06315 2c0da56bf4c3e2377cff54f8d1d2aa0e 174 SUPERFAMILY SSF49329 29 170 1.14E-40 T 15-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_06315 2c0da56bf4c3e2377cff54f8d1d2aa0e 174 Gene3D G3DSA:2.60.40.200 24 174 3.0E-48 T 15-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_06315 2c0da56bf4c3e2377cff54f8d1d2aa0e 174 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 35 170 3.5E-37 T 15-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_06315 2c0da56bf4c3e2377cff54f8d1d2aa0e 174 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 145 171 9.6E-5 T 15-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_06315 2c0da56bf4c3e2377cff54f8d1d2aa0e 174 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 102 111 9.6E-5 T 15-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 C2I28_24700 35db7d49832cdb2062061c4308264769 465 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 30 442 2.2E-50 T 15-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 C2I28_24700 35db7d49832cdb2062061c4308264769 465 Gene3D G3DSA:1.10.4160.10 11 462 1.5E-97 T 15-10-2018 IPR038271 Purine-cytosine permease superfamily C2I28_13660 9cd1db91121cd2783ab1070b7b0b2fd9 295 Pfam PF00483 Nucleotidyl transferase 6 262 4.1E-35 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_13660 9cd1db91121cd2783ab1070b7b0b2fd9 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 8.4E-118 T 15-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 C2I28_13660 9cd1db91121cd2783ab1070b7b0b2fd9 295 Gene3D G3DSA:3.90.550.10 1 290 2.1E-94 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13660 9cd1db91121cd2783ab1070b7b0b2fd9 295 SUPERFAMILY SSF53448 5 274 1.88E-68 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_12825 5eb075f34f175ce218f2c1c2006a69d5 422 SUPERFAMILY SSF50685 363 411 1.67E-7 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_12825 5eb075f34f175ce218f2c1c2006a69d5 422 Pfam PF06725 3D domain 362 422 2.9E-18 T 15-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I28_22435 d15b4f18980d07fb6aac3644c8b2e4fa 192 SUPERFAMILY SSF56784 3 186 3.91E-28 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_22435 d15b4f18980d07fb6aac3644c8b2e4fa 192 Gene3D G3DSA:1.10.150.240 13 75 2.3E-33 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_22435 d15b4f18980d07fb6aac3644c8b2e4fa 192 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 165 3.8E-21 T 15-10-2018 C2I28_22435 d15b4f18980d07fb6aac3644c8b2e4fa 192 Gene3D G3DSA:3.40.50.1000 3 161 2.3E-33 T 15-10-2018 IPR023214 HAD superfamily C2I28_22435 d15b4f18980d07fb6aac3644c8b2e4fa 192 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 3 160 5.2E-7 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 SUPERFAMILY SSF46894 130 230 1.57E-32 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 SMART SM00448 3 113 5.7E-46 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 Gene3D G3DSA:3.40.50.2300 1 130 7.7E-40 T 15-10-2018 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 Pfam PF00072 Response regulator receiver domain 5 114 2.0E-29 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 SMART SM00862 153 229 2.6E-28 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 1.4E-27 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 Gene3D G3DSA:1.10.10.10 131 235 6.7E-42 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_07875 df23b50e59fdae9f7f16496fc4371ff6 235 SUPERFAMILY SSF52172 2 124 5.98E-44 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 PIRSF PIRSF037226 1 388 5.1E-173 T 15-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 SUPERFAMILY SSF53187 3 374 6.28E-61 T 15-10-2018 C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 Pfam PF07687 Peptidase dimerisation domain 170 256 3.9E-10 T 15-10-2018 IPR011650 Peptidase M20, dimerisation domain C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 SUPERFAMILY SSF55031 166 271 4.32E-24 T 15-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 Gene3D G3DSA:3.30.70.360 164 281 1.2E-138 T 15-10-2018 C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 333 6.3E-62 T 15-10-2018 IPR017439 Amidohydrolase GO:0016787 C2I28_09755 e114efccbd287ed06b82c90af9b8e18e 388 Gene3D G3DSA:3.40.630.10 18 361 1.2E-138 T 15-10-2018 C2I28_17805 1eba0a4792bfbd339f08a0d0aacd5e01 186 SUPERFAMILY SSF52540 2 177 4.23E-33 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17805 1eba0a4792bfbd339f08a0d0aacd5e01 186 PIRSF PIRSF006135 1 181 8.5E-43 T 15-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 C2I28_17805 1eba0a4792bfbd339f08a0d0aacd5e01 186 Gene3D G3DSA:3.40.50.300 2 178 9.6E-46 T 15-10-2018 C2I28_17805 1eba0a4792bfbd339f08a0d0aacd5e01 186 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 174 2.6E-41 T 15-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 C2I28_04395 4a17d8254e887b3cb4933e9c352ab293 379 Pfam PF04055 Radical SAM superfamily 8 176 8.4E-25 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_04395 4a17d8254e887b3cb4933e9c352ab293 379 Pfam PF06969 HemN C-terminal domain 302 366 3.7E-16 T 15-10-2018 IPR010723 HemN, C-terminal C2I28_04395 4a17d8254e887b3cb4933e9c352ab293 379 Gene3D G3DSA:3.80.30.20 3 301 2.3E-103 T 15-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe C2I28_04395 4a17d8254e887b3cb4933e9c352ab293 379 SMART SM00729 2 222 1.4E-58 T 15-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 C2I28_04395 4a17d8254e887b3cb4933e9c352ab293 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 367 2.1E-128 T 15-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 C2I28_04395 4a17d8254e887b3cb4933e9c352ab293 379 SUPERFAMILY SSF102114 5 376 1.83E-119 T 15-10-2018 C2I28_10170 e23451783eee32554094066d18889d42 288 Gene3D G3DSA:1.20.120.330 115 232 1.9E-47 T 15-10-2018 C2I28_10170 e23451783eee32554094066d18889d42 288 Pfam PF14540 Nucleotidyltransferase-like 1 118 3.1E-46 T 15-10-2018 IPR029348 Nucleotidyltransferase-like domain C2I28_10170 e23451783eee32554094066d18889d42 288 ProDom PD128250 YGXA BH0953 1 277 7.0E-91 T 15-10-2018 C2I28_10170 e23451783eee32554094066d18889d42 288 Gene3D G3DSA:3.30.460.10 1 114 2.6E-44 T 15-10-2018 C2I28_24270 8dbb01c2e90e59d50c63ba1b36a8b869 188 SUPERFAMILY SSF55729 1 177 4.01E-29 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24270 8dbb01c2e90e59d50c63ba1b36a8b869 188 Gene3D G3DSA:3.40.630.30 2 188 2.7E-33 T 15-10-2018 C2I28_24270 8dbb01c2e90e59d50c63ba1b36a8b869 188 Pfam PF13302 Acetyltransferase (GNAT) domain 9 152 5.4E-18 T 15-10-2018 IPR000182 GNAT domain C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 SUPERFAMILY SSF102114 114 357 4.05E-33 T 15-10-2018 C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 Gene3D G3DSA:3.20.20.70 63 348 1.6E-118 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 Pfam PF13353 4Fe-4S single cluster domain 127 198 5.8E-5 T 15-10-2018 C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 TIGRFAM TIGR00238 TIGR00238: KamA family protein 13 342 1.5E-147 T 15-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 PIRSF PIRSF004911 2 399 2.2E-160 T 15-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 Pfam PF12544 Lysine-2,3-aminomutase 321 447 1.2E-58 T 15-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 21 427 1.2E-190 T 15-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 C2I28_19945 3e7cdf04a0bb92d4a562ac752383db33 469 Gene3D G3DSA:2.40.50.600 349 413 1.2E-18 T 15-10-2018 C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 SMART SM00895 100 228 1.3E-19 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 SMART SM00345 18 77 1.3E-23 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 Pfam PF07729 FCD domain 100 227 6.2E-23 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 SUPERFAMILY SSF48008 98 235 1.44E-24 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 9.8E-11 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 9.8E-11 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.6E-20 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 Gene3D G3DSA:1.20.120.530 98 236 8.7E-26 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 SUPERFAMILY SSF46785 7 81 6.04E-25 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16190 324d66bf03af609fe3c3089e5f46c127 236 Gene3D G3DSA:1.10.10.10 2 91 5.5E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13090 542d9ccfabea1c9c44f9bccd9073b08c 48 Pfam PF12841 YvrJ protein family 9 43 2.3E-13 T 15-10-2018 IPR024419 Protein of unknown function YvrJ C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.6 T 15-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 130 2.5E-15 T 15-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 4.0E-39 T 15-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 4.3E-29 T 15-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 129 5.1E-41 T 15-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 SUPERFAMILY SSF46604 87 131 1.86E-9 T 15-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 Gene3D G3DSA:1.20.5.440 89 133 6.6E-17 T 15-10-2018 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 Gene3D G3DSA:2.60.15.10 1 88 1.0E-32 T 15-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_07310 153df05046f5a1cd1b389d1d31cafc82 134 SUPERFAMILY SSF51344 2 84 9.29E-24 T 15-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 C2I28_15600 97cc7c3ffca7f15db0df9faf651056bb 212 Pfam PF13437 HlyD family secretion protein 87 195 3.4E-13 T 15-10-2018 C2I28_15600 97cc7c3ffca7f15db0df9faf651056bb 212 Gene3D G3DSA:2.40.30.170 113 210 2.8E-17 T 15-10-2018 C2I28_15600 97cc7c3ffca7f15db0df9faf651056bb 212 Gene3D G3DSA:2.40.50.100 45 112 4.8E-13 T 15-10-2018 C2I28_15600 97cc7c3ffca7f15db0df9faf651056bb 212 SUPERFAMILY SSF51230 39 112 5.5E-13 T 15-10-2018 IPR011053 Single hybrid motif C2I28_15600 97cc7c3ffca7f15db0df9faf651056bb 212 SUPERFAMILY SSF111369 71 210 6.67E-5 T 15-10-2018 C2I28_10725 66b1a75c2bb550ab4a087baed8e97f30 131 SUPERFAMILY SSF82199 11 114 1.06E-22 T 15-10-2018 C2I28_10725 66b1a75c2bb550ab4a087baed8e97f30 131 PIRSF PIRSF022536 1 131 9.3E-34 T 15-10-2018 IPR009207 Histone methyltransferase, PBCV type putative KEGG: 00310+2.1.1.43 C2I28_10725 66b1a75c2bb550ab4a087baed8e97f30 131 SMART SM00317 2 117 6.0E-7 T 15-10-2018 IPR001214 SET domain GO:0005515 C2I28_10725 66b1a75c2bb550ab4a087baed8e97f30 131 Gene3D G3DSA:2.170.270.10 1 114 2.6E-29 T 15-10-2018 C2I28_10725 66b1a75c2bb550ab4a087baed8e97f30 131 Pfam PF00856 SET domain 16 111 4.9E-13 T 15-10-2018 IPR001214 SET domain GO:0005515 C2I28_05885 3f731689d03537a2948e78390c0e81c2 268 Gene3D G3DSA:1.10.3720.10 68 266 3.7E-23 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_05885 3f731689d03537a2948e78390c0e81c2 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 264 2.1E-23 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_05885 3f731689d03537a2948e78390c0e81c2 268 SUPERFAMILY SSF161098 71 252 7.33E-30 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_27325 f28ae9c12687cf64af89bc6d32559ba4 162 Pfam PF07552 Spore Coat Protein X and V domain 47 100 1.4E-10 T 15-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I28_27325 f28ae9c12687cf64af89bc6d32559ba4 162 Pfam PF07552 Spore Coat Protein X and V domain 111 161 1.3E-11 T 15-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I28_26980 d570232d20b30d5bbaba5bb95d37453b 221 ProDom PD114754 YWBB 1 220 1.0E-61 T 15-10-2018 IPR024250 Protein of unknown function DUF2711 C2I28_26980 d570232d20b30d5bbaba5bb95d37453b 221 Pfam PF10924 Protein of unknown function (DUF2711) 12 219 5.4E-79 T 15-10-2018 IPR024250 Protein of unknown function DUF2711 C2I28_08155 a6d4496a8a6deb15f8b53089dbeece1c 89 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 7 88 2.4E-23 T 15-10-2018 IPR010001 SigmaK-factor processing regulatory BofA C2I28_08155 a6d4496a8a6deb15f8b53089dbeece1c 89 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 13 86 7.1E-18 T 15-10-2018 IPR010001 SigmaK-factor processing regulatory BofA C2I28_05465 aa190bf1cf7cf45786895e42f9ad22b8 312 Pfam PF02272 DHHA1 domain 177 308 1.7E-14 T 15-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I28_05465 aa190bf1cf7cf45786895e42f9ad22b8 312 SUPERFAMILY SSF64182 13 305 3.4E-71 T 15-10-2018 IPR038763 DHH phosphoesterase superfamily C2I28_05465 aa190bf1cf7cf45786895e42f9ad22b8 312 Gene3D G3DSA:3.10.310.30 199 312 4.0E-36 T 15-10-2018 C2I28_05465 aa190bf1cf7cf45786895e42f9ad22b8 312 Pfam PF01368 DHH family 15 153 1.2E-13 T 15-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 C2I28_05465 aa190bf1cf7cf45786895e42f9ad22b8 312 Gene3D G3DSA:3.90.1640.10 1 197 2.1E-60 T 15-10-2018 C2I28_08965 411220984fc027edea1096c5f61c3944 53 Gene3D G3DSA:1.20.58.990 4 52 9.8E-8 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_08965 411220984fc027edea1096c5f61c3944 53 Pfam PF09388 Spo0E like sporulation regulatory protein 8 49 2.1E-13 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_08965 411220984fc027edea1096c5f61c3944 53 SUPERFAMILY SSF140500 5 50 5.49E-12 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_14160 c534d0529259ec17310754123fb844b2 361 Gene3D G3DSA:3.30.300.210 211 361 1.7E-12 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_14160 c534d0529259ec17310754123fb844b2 361 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 360 4.1E-75 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_14160 c534d0529259ec17310754123fb844b2 361 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 195 358 3.1E-24 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_10360 e720c3226be8a14495522dcd0a14bcf6 343 Gene3D G3DSA:1.20.1260.10 8 144 5.8E-8 T 15-10-2018 IPR012347 Ferritin-like C2I28_10360 e720c3226be8a14495522dcd0a14bcf6 343 Gene3D G3DSA:1.20.1260.10 184 327 1.3E-5 T 15-10-2018 IPR012347 Ferritin-like C2I28_10360 e720c3226be8a14495522dcd0a14bcf6 343 Pfam PF11553 Protein of unknown function (DUF3231) 11 169 3.9E-39 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_10360 e720c3226be8a14495522dcd0a14bcf6 343 Pfam PF11553 Protein of unknown function (DUF3231) 181 340 1.6E-44 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_24115 4bc158ac57f275aa18ede042c692473e 127 Pfam PF12680 SnoaL-like domain 6 110 6.3E-7 T 15-10-2018 IPR037401 SnoaL-like domain C2I28_24115 4bc158ac57f275aa18ede042c692473e 127 SUPERFAMILY SSF54427 4 117 1.06E-21 T 15-10-2018 IPR032710 NTF2-like domain superfamily C2I28_24115 4bc158ac57f275aa18ede042c692473e 127 Gene3D G3DSA:3.10.450.50 1 127 8.8E-45 T 15-10-2018 C2I28_01740 afb1208b9811c5c719c677ad4484b73d 345 Pfam PF01757 Acyltransferase family 5 308 1.9E-19 T 15-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 15-10-2018 IPR019844 Cold-shock conserved site C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 SMART SM00357 3 66 2.2E-31 T 15-10-2018 IPR011129 Cold shock domain GO:0003676 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.3E-31 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 PRINTS PR00050 Cold shock protein signature 4 19 5.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 PRINTS PR00050 Cold shock protein signature 24 33 5.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 PRINTS PR00050 Cold shock protein signature 39 57 5.4E-19 T 15-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 PIRSF PIRSF002599 1 67 3.9E-26 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 SUPERFAMILY SSF50249 1 66 1.07E-25 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_15360 4a9fcfab8f569ba84f366cead2a89f67 67 Gene3D G3DSA:2.40.50.140 1 66 2.1E-31 T 15-10-2018 C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 4.8E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 SUPERFAMILY SSF48008 83 222 4.18E-20 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 SMART SM00345 20 78 2.8E-16 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 Gene3D G3DSA:1.20.120.530 74 226 1.9E-18 T 15-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 Gene3D G3DSA:1.10.10.10 13 73 2.5E-19 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 SMART SM00895 87 216 1.2E-7 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 7.1E-8 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 7.1E-8 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 Pfam PF07729 FCD domain 87 215 7.5E-16 T 15-10-2018 IPR011711 GntR, C-terminal C2I28_22295 ec782ee8ea4c2a9661d857e19ab85eab 229 SUPERFAMILY SSF46785 11 81 3.62E-16 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_13845 3301a2ab73ca985baaf937b7f9b30846 248 SUPERFAMILY SSF52266 84 246 4.12E-10 T 15-10-2018 C2I28_13845 3301a2ab73ca985baaf937b7f9b30846 248 Gene3D G3DSA:3.40.50.1110 68 246 5.3E-10 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_08825 811708086f9e09c9f018149457863dc7 120 Pfam PF01196 Ribosomal protein L17 16 120 4.9E-39 T 15-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08825 811708086f9e09c9f018149457863dc7 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 15-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08825 811708086f9e09c9f018149457863dc7 120 SUPERFAMILY SSF64263 2 120 5.49E-44 T 15-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08825 811708086f9e09c9f018149457863dc7 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 120 4.2E-48 T 15-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08825 811708086f9e09c9f018149457863dc7 120 Gene3D G3DSA:3.90.1030.10 1 120 1.6E-49 T 15-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_08825 811708086f9e09c9f018149457863dc7 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.501 T 15-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_26910 a6162cd565ca5856ebee2e73b2eabc73 798 TIGRFAM TIGR03238 dnd_assoc_3: DNA phosphorothioation-dependent restriction protein DptF 214 772 5.4E-24 T 15-10-2018 IPR017647 DNA phosphorothioation-dependent restriction protein DptF C2I28_12670 f59c060fd4f92dc6ac185c5a1c5dec4a 161 Gene3D G3DSA:3.40.630.30 1 161 2.8E-38 T 15-10-2018 C2I28_12670 f59c060fd4f92dc6ac185c5a1c5dec4a 161 Pfam PF00583 Acetyltransferase (GNAT) family 45 137 3.8E-17 T 15-10-2018 IPR000182 GNAT domain C2I28_12670 f59c060fd4f92dc6ac185c5a1c5dec4a 161 SUPERFAMILY SSF55729 3 149 8.7E-32 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22875 3fe31cd04bab70af092b8665ca9ef77b 214 Pfam PF01081 KDPG and KHG aldolase 4 189 8.1E-42 T 15-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I28_22875 3fe31cd04bab70af092b8665ca9ef77b 214 SUPERFAMILY SSF51569 3 191 1.03E-61 T 15-10-2018 C2I28_22875 3fe31cd04bab70af092b8665ca9ef77b 214 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 4 200 1.6E-54 T 15-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 C2I28_22875 3fe31cd04bab70af092b8665ca9ef77b 214 Gene3D G3DSA:3.20.20.70 1 212 1.5E-73 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_11625 c209eeb22c93488ef07ef387463f77fb 246 Gene3D G3DSA:3.40.50.1820 31 218 4.2E-6 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11625 c209eeb22c93488ef07ef387463f77fb 246 SUPERFAMILY SSF53474 47 149 1.4E-8 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_03295 9903401adf29e181f3b398794c77cfb4 195 SMART SM00563 37 149 3.4E-32 T 15-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I28_03295 9903401adf29e181f3b398794c77cfb4 195 Pfam PF01553 Acyltransferase 24 146 1.9E-22 T 15-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I28_03295 9903401adf29e181f3b398794c77cfb4 195 SUPERFAMILY SSF69593 5 192 1.7E-51 T 15-10-2018 C2I28_07500 191d58976fd58a94c273016beeec9356 387 PIRSF PIRSF000429 2 387 1.0E-112 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 386 4.1E-132 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 ProSitePatterns PS00737 Thiolases signature 2. 334 350 - T 15-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 ProSitePatterns PS00099 Thiolases active site. 369 382 - T 15-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 SUPERFAMILY SSF53901 266 386 4.94E-39 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_07500 191d58976fd58a94c273016beeec9356 387 Pfam PF00108 Thiolase, N-terminal domain 5 258 1.3E-85 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 Gene3D G3DSA:3.40.47.10 122 385 1.4E-137 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_07500 191d58976fd58a94c273016beeec9356 387 Gene3D G3DSA:3.40.47.10 5 271 1.4E-137 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_07500 191d58976fd58a94c273016beeec9356 387 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 80 98 - T 15-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 Pfam PF02803 Thiolase, C-terminal domain 266 386 3.7E-43 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_07500 191d58976fd58a94c273016beeec9356 387 SUPERFAMILY SSF53901 4 264 2.76E-76 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_19405 de9e8a99bb1f41285f6ea276f02ee1dd 125 SUPERFAMILY SSF50729 6 124 1.29E-45 T 15-10-2018 C2I28_19405 de9e8a99bb1f41285f6ea276f02ee1dd 125 Gene3D G3DSA:2.30.29.50 1 125 1.3E-52 T 15-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily C2I28_19405 de9e8a99bb1f41285f6ea276f02ee1dd 125 Pfam PF08000 Bacterial PH domain 3 123 2.7E-49 T 15-10-2018 IPR012544 Bacterial Pleckstrin homology domain C2I28_07470 485a95f289ddc73b6854709da4b4d2fd 178 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 14 83 6.8E-12 T 15-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 C2I28_07470 485a95f289ddc73b6854709da4b4d2fd 178 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 171 14.895 T 15-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 C2I28_07470 485a95f289ddc73b6854709da4b4d2fd 178 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 94 2.5E-33 T 15-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 C2I28_07470 485a95f289ddc73b6854709da4b4d2fd 178 Gene3D G3DSA:1.10.10.1250 2 84 5.5E-31 T 15-10-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily C2I28_25220 ad5cc8e02f9f265b9234f3ace5cc420a 87 Pfam PF14150 YesK-like protein 14 82 1.6E-6 T 15-10-2018 IPR025434 YesK-like protein C2I28_16675 105adca2c855cc4a3782bfa88264b943 174 Gene3D G3DSA:3.40.630.30 4 171 4.7E-50 T 15-10-2018 C2I28_16675 105adca2c855cc4a3782bfa88264b943 174 Pfam PF13302 Acetyltransferase (GNAT) domain 5 138 3.8E-21 T 15-10-2018 IPR000182 GNAT domain C2I28_16675 105adca2c855cc4a3782bfa88264b943 174 SUPERFAMILY SSF55729 3 162 5.74E-40 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_27430 df96567bfc3bbf6a1a84495118ba3ba9 238 Gene3D G3DSA:3.90.550.10 1 237 7.2E-58 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_27430 df96567bfc3bbf6a1a84495118ba3ba9 238 SUPERFAMILY SSF53448 3 224 4.17E-54 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_27430 df96567bfc3bbf6a1a84495118ba3ba9 238 Pfam PF00535 Glycosyl transferase family 2 5 132 5.0E-27 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_11020 a6bb2a616563252d22f2f494e0f41b89 61 Pfam PF14120 YhzD-like protein 1 61 1.0E-29 T 15-10-2018 IPR025544 YhzD-like protein C2I28_01070 30e88e5a4dbaff7d190fcfe8e9f1afee 477 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_01070 30e88e5a4dbaff7d190fcfe8e9f1afee 477 Pfam PF00324 Amino acid permease 19 458 3.3E-124 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_01070 30e88e5a4dbaff7d190fcfe8e9f1afee 477 PIRSF PIRSF006060 4 475 1.6E-89 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_01070 30e88e5a4dbaff7d190fcfe8e9f1afee 477 Gene3D G3DSA:1.20.1740.10 10 475 3.4E-70 T 15-10-2018 C2I28_26815 3cc17614dfe6f622b870ff1cc3c7a596 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_26815 3cc17614dfe6f622b870ff1cc3c7a596 70 Gene3D G3DSA:1.10.8.910 10 69 2.3E-31 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_26815 3cc17614dfe6f622b870ff1cc3c7a596 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 3.5E-22 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_26815 3cc17614dfe6f622b870ff1cc3c7a596 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_27370 05bde9ee16c7e222b8a4a157e931ceb3 391 SUPERFAMILY SSF56059 112 293 3.54E-22 T 15-10-2018 C2I28_27370 05bde9ee16c7e222b8a4a157e931ceb3 391 Gene3D G3DSA:3.30.470.20 109 353 2.1E-14 T 15-10-2018 C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 SUPERFAMILY SSF51735 2 226 5.29E-42 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 Pfam PF00106 short chain dehydrogenase 3 194 2.6E-32 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 Gene3D G3DSA:3.40.50.720 1 236 8.0E-43 T 15-10-2018 C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_19725 20ad06dbcc6f740f5b020d0b19065b52 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.4E-12 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_07825 cdcde5a2837e8b48d5d24933252097b4 131 PRINTS PR00502 NUDIX hydrolase family signature 34 48 8.6E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_07825 cdcde5a2837e8b48d5d24933252097b4 131 PRINTS PR00502 NUDIX hydrolase family signature 48 63 8.6E-5 T 15-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 C2I28_07825 cdcde5a2837e8b48d5d24933252097b4 131 Gene3D G3DSA:3.90.79.10 1 130 4.8E-31 T 15-10-2018 C2I28_07825 cdcde5a2837e8b48d5d24933252097b4 131 SUPERFAMILY SSF55811 3 128 9.88E-32 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_07825 cdcde5a2837e8b48d5d24933252097b4 131 Pfam PF00293 NUDIX domain 5 119 1.6E-15 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_18345 44539b228675ce146a88e4f78eeb1a8e 93 Gene3D G3DSA:1.20.90.10 3 92 6.9E-14 T 15-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 C2I28_18345 44539b228675ce146a88e4f78eeb1a8e 93 ProSitePatterns PS00118 Phospholipase A2 histidine active site. 37 44 - T 15-10-2018 IPR033113 Phospholipase A2, histidine active site KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783|Reactome: R-HSA-1482788|Reactome: R-HSA-1482801|Reactome: R-HSA-1482839|Reactome: R-HSA-1482922|Reactome: R-HSA-1482925|Reactome: R-HSA-1483166 C2I28_18345 44539b228675ce146a88e4f78eeb1a8e 93 SUPERFAMILY SSF48619 14 70 4.2E-11 T 15-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 C2I28_16885 3d63dbe44b047eea2f5eaafd9c6c2114 90 Pfam PF04226 Transglycosylase associated protein 33 77 5.6E-10 T 15-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 C2I28_02195 2ce5edac0be5bf5924fa2d4519425ec3 430 Gene3D G3DSA:3.30.830.10 241 429 6.3E-46 T 15-10-2018 C2I28_02195 2ce5edac0be5bf5924fa2d4519425ec3 430 Pfam PF05193 Peptidase M16 inactive domain 185 364 2.2E-20 T 15-10-2018 IPR007863 Peptidase M16, C-terminal C2I28_02195 2ce5edac0be5bf5924fa2d4519425ec3 430 Pfam PF00675 Insulinase (Peptidase family M16) 66 177 3.2E-17 T 15-10-2018 IPR011765 Peptidase M16, N-terminal C2I28_02195 2ce5edac0be5bf5924fa2d4519425ec3 430 Gene3D G3DSA:3.30.830.10 10 240 1.5E-61 T 15-10-2018 C2I28_02195 2ce5edac0be5bf5924fa2d4519425ec3 430 SUPERFAMILY SSF63411 17 222 1.03E-42 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_02195 2ce5edac0be5bf5924fa2d4519425ec3 430 SUPERFAMILY SSF63411 259 428 1.48E-20 T 15-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 C2I28_26470 1ea03445817b55a451de177d77286798 276 SUPERFAMILY SSF53335 51 255 4.07E-18 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_26470 1ea03445817b55a451de177d77286798 276 Gene3D G3DSA:3.40.50.150 6 268 3.6E-20 T 15-10-2018 C2I28_26470 1ea03445817b55a451de177d77286798 276 Pfam PF04072 Leucine carboxyl methyltransferase 43 180 3.3E-16 T 15-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 SUPERFAMILY SSF53795 132 297 1.34E-42 T 15-10-2018 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 Gene3D G3DSA:3.40.50.300 132 311 1.7E-75 T 15-10-2018 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 Pfam PF02603 HPr Serine kinase N terminus 4 127 6.8E-41 T 15-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 1.5E-77 T 15-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 SUPERFAMILY SSF75138 3 131 1.7E-40 T 15-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 301 2.6E-120 T 15-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.401 T 15-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 C2I28_06955 678a77f161eee068ea59db5341ae16ae 311 Gene3D G3DSA:3.40.1390.20 1 131 3.2E-44 T 15-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 4.1E-12 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 4.1E-12 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 4.1E-12 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 Pfam PF00209 Sodium:neurotransmitter symporter family 5 125 3.5E-24 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 Pfam PF00209 Sodium:neurotransmitter symporter family 146 443 8.0E-33 T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 15-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 C2I28_18550 3bc02471fd8cb4e6b396c1b24082e7ac 444 SUPERFAMILY SSF161070 5 442 7.85E-131 T 15-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 C2I28_05410 eba70fe50b61785aae2aecce36fa6573 153 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 1.0E-29 T 15-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame C2I28_05410 eba70fe50b61785aae2aecce36fa6573 153 Pfam PF04284 Protein of unknown function (DUF441) 7 146 3.9E-48 T 15-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame C2I28_05410 eba70fe50b61785aae2aecce36fa6573 153 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 18.946 T 15-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame C2I28_23930 808904d714a8b347f1118a871bb5fab5 72 Pfam PF07872 Protein of unknown function (DUF1659) 8 46 6.3E-8 T 15-10-2018 IPR012454 Protein of unknown function DUF1659 C2I28_00870 22ea0ffb412bffb9f9d97b674974a248 93 SUPERFAMILY SSF103473 6 91 1.57E-5 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_02720 67b0206f6ae6b14dbf3a7999db8b4d54 62 Gene3D G3DSA:2.30.170.40 19 62 2.1E-18 T 15-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02720 67b0206f6ae6b14dbf3a7999db8b4d54 62 SUPERFAMILY SSF143800 1 61 1.06E-22 T 15-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02720 67b0206f6ae6b14dbf3a7999db8b4d54 62 Pfam PF00830 Ribosomal L28 family 3 58 2.0E-19 T 15-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02720 67b0206f6ae6b14dbf3a7999db8b4d54 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.152 T 15-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02720 67b0206f6ae6b14dbf3a7999db8b4d54 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 1.0E-21 T 15-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 422 437 - T 15-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 15-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 Gene3D G3DSA:3.30.450.20 214 311 2.0E-9 T 15-10-2018 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 Pfam PF08461 Ribonuclease R winged-helix domain 616 669 1.2E-7 T 15-10-2018 IPR013668 Ribonuclease R winged-helix domain C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 SUPERFAMILY SSF52540 334 573 1.81E-63 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 SMART SM00382 355 503 6.3E-10 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 Gene3D G3DSA:3.40.50.300 322 506 3.7E-63 T 15-10-2018 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 Pfam PF00158 Sigma-54 interaction domain 335 502 2.7E-65 T 15-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 Gene3D G3DSA:1.10.8.60 507 580 2.3E-18 T 15-10-2018 C2I28_16045 3dd7305ce2d8e038c6775406c88ef8b7 681 Gene3D G3DSA:1.10.10.10 594 680 1.5E-6 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11180 4a5d161d2f7ebbe1013fd71c36177cd4 429 Gene3D G3DSA:3.40.190.10 60 364 1.1E-94 T 15-10-2018 C2I28_11180 4a5d161d2f7ebbe1013fd71c36177cd4 429 Pfam PF13416 Bacterial extracellular solute-binding protein 60 363 1.6E-51 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_11180 4a5d161d2f7ebbe1013fd71c36177cd4 429 SUPERFAMILY SSF53850 21 427 2.21E-72 T 15-10-2018 C2I28_11180 4a5d161d2f7ebbe1013fd71c36177cd4 429 Gene3D G3DSA:3.40.190.10 147 418 1.1E-94 T 15-10-2018 C2I28_11180 4a5d161d2f7ebbe1013fd71c36177cd4 429 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 146 163 - T 15-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 Gene3D G3DSA:3.50.50.60 6 338 4.1E-101 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 Gene3D G3DSA:3.30.9.50 72 266 4.1E-101 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 327 6.6E-42 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 6.6E-42 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 6.6E-42 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 343 6.6E-42 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 6.6E-42 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 6.6E-42 T 15-10-2018 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 Pfam PF01494 FAD binding domain 5 340 1.3E-78 T 15-10-2018 IPR002938 FAD-binding domain GO:0071949 C2I28_22635 e4b9798d10b06d1d1b3da6333f12d2ca 504 SUPERFAMILY SSF51905 4 370 6.98E-62 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-8 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 Gene3D G3DSA:1.10.10.10 1 84 3.2E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 Gene3D G3DSA:3.40.190.290 90 294 1.5E-52 T 15-10-2018 C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.6E-19 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 Pfam PF03466 LysR substrate binding domain 89 288 1.5E-46 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 SUPERFAMILY SSF46785 2 82 5.1E-19 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24735 d9e4aa8f34ee4f8778383d63f66340e6 294 SUPERFAMILY SSF53850 88 292 7.6E-41 T 15-10-2018 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 143 167 3.5E-12 T 15-10-2018 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 307 331 3.5E-12 T 15-10-2018 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 3.5E-12 T 15-10-2018 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 PRINTS PR01036 Tetracycline resistance protein TetB signature 113 133 3.5E-12 T 15-10-2018 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 Gene3D G3DSA:1.20.1720.10 19 229 3.4E-46 T 15-10-2018 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 Pfam PF07690 Major Facilitator Superfamily 23 414 5.1E-52 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 SUPERFAMILY SSF103473 9 513 1.44E-73 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_12775 be4e6d9eb7b3430ad738ed8b8f85c395 541 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 508 8.2E-158 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_22085 14a83cc732ae8fdaac5fba73b7f50121 393 Pfam PF07670 Nucleoside recognition 91 188 1.3E-6 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_22085 14a83cc732ae8fdaac5fba73b7f50121 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 1.3E-21 T 15-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 C2I28_22085 14a83cc732ae8fdaac5fba73b7f50121 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 2.2E-57 T 15-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 C2I28_19770 174c27a3c28d6e6ee70b590e9253d6fe 191 SUPERFAMILY SSF55729 3 174 1.17E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_19770 174c27a3c28d6e6ee70b590e9253d6fe 191 Gene3D G3DSA:3.40.630.30 1 154 2.2E-18 T 15-10-2018 C2I28_19770 174c27a3c28d6e6ee70b590e9253d6fe 191 Pfam PF00583 Acetyltransferase (GNAT) family 47 150 8.6E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_12590 76ce7c7176ae1aaeeb976b18bfc2f75e 453 Pfam PF02378 Phosphotransferase system, EIIC 118 387 9.6E-40 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_12590 76ce7c7176ae1aaeeb976b18bfc2f75e 453 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_12590 76ce7c7176ae1aaeeb976b18bfc2f75e 453 Gene3D G3DSA:3.30.1360.60 3 78 3.4E-22 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_12590 76ce7c7176ae1aaeeb976b18bfc2f75e 453 Pfam PF00367 phosphotransferase system, EIIB 10 42 1.2E-13 T 15-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 C2I28_12590 76ce7c7176ae1aaeeb976b18bfc2f75e 453 SUPERFAMILY SSF55604 8 82 2.09E-17 T 15-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 99 230 1.9E-18 T 15-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 55 316 7.3E-133 T 15-10-2018 IPR014232 Sporulation stage V, protein K C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 136 150 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 278 290 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 58 72 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 218 237 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 180 192 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 201 218 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 150 169 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 PRINTS PR00819 CbxX/CfqX superfamily signature 98 113 6.0E-60 T 15-10-2018 IPR000641 CbxX/CfqX GO:0005524 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 Gene3D G3DSA:3.40.50.300 36 230 4.0E-57 T 15-10-2018 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 Gene3D G3DSA:1.10.8.60 231 318 1.1E-19 T 15-10-2018 C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 SMART SM00382 95 233 1.1E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_02085 8ba525a5b2ed1382ec1404190d86c5da 318 SUPERFAMILY SSF52540 57 300 1.32E-40 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18755 c09a2b19a608ca12aeb3c15efa056650 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 27.396 T 15-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 C2I28_18755 c09a2b19a608ca12aeb3c15efa056650 208 Gene3D G3DSA:3.40.50.360 1 208 3.8E-62 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_18755 c09a2b19a608ca12aeb3c15efa056650 208 Pfam PF02525 Flavodoxin-like fold 3 203 3.5E-45 T 15-10-2018 IPR003680 Flavodoxin-like fold C2I28_18755 c09a2b19a608ca12aeb3c15efa056650 208 SUPERFAMILY SSF52218 1 207 1.02E-51 T 15-10-2018 IPR029039 Flavoprotein-like superfamily C2I28_24905 e5fe54a9cc12ab4b6a60b9f88465de28 167 Pfam PF07308 Protein of unknown function (DUF1456) 101 167 1.3E-21 T 15-10-2018 IPR009921 Domain of unknown function DUF1456 C2I28_24905 e5fe54a9cc12ab4b6a60b9f88465de28 167 Pfam PF07308 Protein of unknown function (DUF1456) 3 79 1.3E-26 T 15-10-2018 IPR009921 Domain of unknown function DUF1456 C2I28_06700 6df040455eeedb11e88f7fc7111ca375 375 Gene3D G3DSA:3.40.50.2000 181 345 1.9E-19 T 15-10-2018 C2I28_06700 6df040455eeedb11e88f7fc7111ca375 375 SUPERFAMILY SSF53756 72 351 4.4E-27 T 15-10-2018 C2I28_06700 6df040455eeedb11e88f7fc7111ca375 375 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 181 3.2E-33 T 15-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 C2I28_06700 6df040455eeedb11e88f7fc7111ca375 375 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 199 340 7.1E-5 T 15-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 C2I28_12455 d81df52af6bea21aca68e612ef5163f5 223 Pfam PF00072 Response regulator receiver domain 4 115 3.6E-22 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_12455 d81df52af6bea21aca68e612ef5163f5 223 PIRSF PIRSF006171 1 223 3.0E-74 T 15-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 C2I28_12455 d81df52af6bea21aca68e612ef5163f5 223 Pfam PF08279 HTH domain 173 221 8.1E-6 T 15-10-2018 IPR013196 Helix-turn-helix, type 11 C2I28_12455 d81df52af6bea21aca68e612ef5163f5 223 SUPERFAMILY SSF52172 1 130 2.99E-30 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_12455 d81df52af6bea21aca68e612ef5163f5 223 Gene3D G3DSA:3.40.50.12740 2 207 1.4E-30 T 15-10-2018 C2I28_12455 d81df52af6bea21aca68e612ef5163f5 223 SMART SM00448 2 115 1.2E-22 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_14510 b7885cdd9101e2667c213f860b72a873 612 Gene3D G3DSA:3.20.20.220 310 600 3.8E-52 T 15-10-2018 C2I28_14510 b7885cdd9101e2667c213f860b72a873 612 Pfam PF02219 Methylenetetrahydrofolate reductase 316 573 1.6E-26 T 15-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I28_14510 b7885cdd9101e2667c213f860b72a873 612 Pfam PF02574 Homocysteine S-methyltransferase 12 280 5.0E-55 T 15-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 C2I28_14510 b7885cdd9101e2667c213f860b72a873 612 SUPERFAMILY SSF51730 316 600 2.55E-68 T 15-10-2018 IPR029041 FAD-linked oxidoreductase-like C2I28_14510 b7885cdd9101e2667c213f860b72a873 612 Gene3D G3DSA:3.20.20.330 2 293 9.9E-86 T 15-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I28_14510 b7885cdd9101e2667c213f860b72a873 612 SUPERFAMILY SSF82282 2 359 8.5E-102 T 15-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 C2I28_14865 957bfa9fa6b9557536e7b7c1d4cc3a6e 199 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 5 155 7.2E-40 T 15-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 C2I28_14865 957bfa9fa6b9557536e7b7c1d4cc3a6e 199 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 23 153 8.3E-15 T 15-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I28_07970 0b418af80122c1eaf3f3a83d6bde933c 260 Pfam PF13614 AAA domain 2 178 6.9E-74 T 15-10-2018 IPR025669 AAA domain C2I28_07970 0b418af80122c1eaf3f3a83d6bde933c 260 PIRSF PIRSF009320 2 50 1.5E-14 T 15-10-2018 C2I28_07970 0b418af80122c1eaf3f3a83d6bde933c 260 PIRSF PIRSF009320 88 259 6.4E-8 T 15-10-2018 C2I28_07970 0b418af80122c1eaf3f3a83d6bde933c 260 SUPERFAMILY SSF52540 1 251 1.36E-70 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07970 0b418af80122c1eaf3f3a83d6bde933c 260 Gene3D G3DSA:3.40.50.300 1 257 4.4E-83 T 15-10-2018 C2I28_05635 ccb8f078a764b81e467792783aecaddd 267 Pfam PF01618 MotA/TolQ/ExbB proton channel family 106 219 8.2E-22 T 15-10-2018 IPR002898 MotA/TolQ/ExbB proton channel C2I28_05635 ccb8f078a764b81e467792783aecaddd 267 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 190 207 - T 15-10-2018 IPR000540 Flagellar motor protein MotA, conserved site C2I28_12970 7b4a9900021a3ba963abda8a68d9c104 251 SUPERFAMILY SSF88713 3 250 4.74E-97 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_12970 7b4a9900021a3ba963abda8a68d9c104 251 Gene3D G3DSA:3.20.20.370 2 251 3.4E-101 T 15-10-2018 C2I28_12970 7b4a9900021a3ba963abda8a68d9c104 251 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 44.22 T 15-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I28_12970 7b4a9900021a3ba963abda8a68d9c104 251 Pfam PF03746 LamB/YcsF family 4 241 9.6E-101 T 15-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 C2I28_19570 25f3631cd715187850c1752cd0eb6e96 310 Gene3D G3DSA:3.40.50.1820 1 307 1.4E-99 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_19570 25f3631cd715187850c1752cd0eb6e96 310 Pfam PF07859 alpha/beta hydrolase fold 76 283 3.7E-76 T 15-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 C2I28_19570 25f3631cd715187850c1752cd0eb6e96 310 SUPERFAMILY SSF53474 53 307 6.46E-72 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_03510 8614d21baa05bf1ab3a94dc953572fb2 140 Pfam PF13782 Stage V sporulation protein AB 27 135 4.4E-34 T 15-10-2018 IPR020144 Stage V sporulation protein AB C2I28_03510 8614d21baa05bf1ab3a94dc953572fb2 140 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 27 139 1.0E-32 T 15-10-2018 IPR020144 Stage V sporulation protein AB C2I28_16640 06f41a5b17a8226b8d8e143151cd525f 271 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_16640 06f41a5b17a8226b8d8e143151cd525f 271 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 18.276 T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_16640 06f41a5b17a8226b8d8e143151cd525f 271 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 260 1.5E-83 T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_16640 06f41a5b17a8226b8d8e143151cd525f 271 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 256 7.6E-81 T 15-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 C2I28_22840 b705bec9a156ce02de95b7dad53fe9e8 523 Pfam PF13520 Amino acid permease 14 422 3.3E-47 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_22840 b705bec9a156ce02de95b7dad53fe9e8 523 Gene3D G3DSA:1.20.1740.10 9 464 3.1E-74 T 15-10-2018 C2I28_22840 b705bec9a156ce02de95b7dad53fe9e8 523 PIRSF PIRSF006060 450 516 340.0 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_22840 b705bec9a156ce02de95b7dad53fe9e8 523 PIRSF PIRSF006060 1 458 4.3E-86 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_15295 fd97a05ac2af4ee078bb35aee70129ca 180 Pfam PF13420 Acetyltransferase (GNAT) domain 21 173 8.2E-20 T 15-10-2018 C2I28_15295 fd97a05ac2af4ee078bb35aee70129ca 180 SUPERFAMILY SSF55729 16 178 2.4E-31 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_15295 fd97a05ac2af4ee078bb35aee70129ca 180 Gene3D G3DSA:3.40.630.30 16 180 7.8E-38 T 15-10-2018 C2I28_05730 93c615a24d57d9499430614a4590ba9e 264 SUPERFAMILY SSF56112 3 225 3.58E-31 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_05730 93c615a24d57d9499430614a4590ba9e 264 Gene3D G3DSA:3.90.1200.10 75 260 1.5E-21 T 15-10-2018 C2I28_05730 93c615a24d57d9499430614a4590ba9e 264 Pfam PF01636 Phosphotransferase enzyme family 20 225 3.9E-21 T 15-10-2018 IPR002575 Aminoglycoside phosphotransferase C2I28_06515 3fbf0816457c6cabd49d6dca721e14f1 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.4E-234 T 15-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 C2I28_06515 3fbf0816457c6cabd49d6dca721e14f1 465 SUPERFAMILY SSF101960 32 462 2.75E-141 T 15-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily C2I28_06515 3fbf0816457c6cabd49d6dca721e14f1 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 1.9E-75 T 15-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 C2I28_11055 e4d769cff544d61b6068ac5eb0acdb98 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 26 8.8E-14 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_11055 e4d769cff544d61b6068ac5eb0acdb98 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 5 28 5.3E-13 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_02795 83d42162b742cb890ae1d8ff5187d5e9 86 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 77 2.0E-28 T 15-10-2018 IPR007169 Extracellular matrix regulatory protein A C2I28_02795 83d42162b742cb890ae1d8ff5187d5e9 86 Hamap MF_01503 UPF0296 protein . 3 85 27.426 T 15-10-2018 IPR007169 Extracellular matrix regulatory protein A C2I28_02795 83d42162b742cb890ae1d8ff5187d5e9 86 Pfam PF04025 Domain of unknown function (DUF370) 5 77 1.7E-35 T 15-10-2018 IPR007169 Extracellular matrix regulatory protein A C2I28_17900 c2dfa2c0112a53c4e03d9c02f9d3ed1c 126 ProDom PD077583 REPLICATION TRANSCRIPTION DNA-BINDING TERMINATOR REGULATION TERMINATION 3D-STRUCTURE 10 123 8.0E-50 T 15-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 C2I28_17900 c2dfa2c0112a53c4e03d9c02f9d3ed1c 126 PIRSF PIRSF021424 1 123 4.3E-67 T 15-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 C2I28_17900 c2dfa2c0112a53c4e03d9c02f9d3ed1c 126 Gene3D G3DSA:1.10.10.10 1 123 4.4E-46 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17900 c2dfa2c0112a53c4e03d9c02f9d3ed1c 126 SUPERFAMILY SSF46785 5 104 9.75E-21 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_17900 c2dfa2c0112a53c4e03d9c02f9d3ed1c 126 Pfam PF02334 Replication terminator protein 2 123 4.2E-57 T 15-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 C2I28_03780 a80728c03aded0d843e54170557d6cf6 303 PIRSF PIRSF000428 1 303 2.7E-85 T 15-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I28_03780 a80728c03aded0d843e54170557d6cf6 303 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 299 3.9E-127 T 15-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 C2I28_03780 a80728c03aded0d843e54170557d6cf6 303 Pfam PF01515 Phosphate acetyl/butaryl transferase 64 296 1.2E-53 T 15-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 C2I28_03780 a80728c03aded0d843e54170557d6cf6 303 SUPERFAMILY SSF53659 4 299 4.17E-63 T 15-10-2018 C2I28_03780 a80728c03aded0d843e54170557d6cf6 303 Gene3D G3DSA:3.40.718.10 1 301 2.5E-106 T 15-10-2018 C2I28_13395 74ea5da434b9438b67a11a82db85afe2 66 Pfam PF11755 Protein of unknown function (DUF3311) 7 65 1.4E-21 T 15-10-2018 IPR021741 Protein of unknown function DUF3311 C2I28_19345 5660f07cdb525c4e5be529a05e54d6fd 108 Pfam PF11181 Heat induced stress protein YflT 4 103 1.2E-29 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_19400 9addad17360f907a5898bd688c32f831 715 Pfam PF12698 ABC-2 family transporter protein 22 182 3.8E-8 T 15-10-2018 C2I28_19400 9addad17360f907a5898bd688c32f831 715 Pfam PF12698 ABC-2 family transporter protein 331 691 1.7E-9 T 15-10-2018 C2I28_19400 9addad17360f907a5898bd688c32f831 715 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 173 8.6E-45 T 15-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal C2I28_19400 9addad17360f907a5898bd688c32f831 715 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 495 694 7.7E-49 T 15-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal C2I28_03840 30bdda231942dc7515729cf4f99b60dd 298 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 217 229 - T 15-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I28_03840 30bdda231942dc7515729cf4f99b60dd 298 SUPERFAMILY SSF48576 5 277 1.71E-84 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_03840 30bdda231942dc7515729cf4f99b60dd 298 Gene3D G3DSA:1.10.600.10 2 298 1.2E-106 T 15-10-2018 IPR008949 Isoprenoid synthase domain superfamily C2I28_03840 30bdda231942dc7515729cf4f99b60dd 298 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 84 100 - T 15-10-2018 IPR033749 Polyprenyl synthetase, conserved site C2I28_03840 30bdda231942dc7515729cf4f99b60dd 298 Pfam PF00348 Polyprenyl synthetase 35 269 2.2E-59 T 15-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 C2I28_15645 95e56c19179622f33685a6a0ad4037a2 264 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15645 95e56c19179622f33685a6a0ad4037a2 264 SMART SM00382 28 217 2.5E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15645 95e56c19179622f33685a6a0ad4037a2 264 Pfam PF00005 ABC transporter 19 167 2.0E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15645 95e56c19179622f33685a6a0ad4037a2 264 Gene3D G3DSA:3.40.50.300 2 258 4.6E-69 T 15-10-2018 C2I28_15645 95e56c19179622f33685a6a0ad4037a2 264 SUPERFAMILY SSF52540 4 230 4.89E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09965 0a8e3094d90e6ff8416d674848c64fd7 394 SUPERFAMILY SSF103473 9 384 3.01E-51 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_09965 0a8e3094d90e6ff8416d674848c64fd7 394 Gene3D G3DSA:1.20.1250.20 6 184 9.8E-25 T 15-10-2018 C2I28_09965 0a8e3094d90e6ff8416d674848c64fd7 394 Pfam PF07690 Major Facilitator Superfamily 217 380 7.2E-20 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_09965 0a8e3094d90e6ff8416d674848c64fd7 394 Gene3D G3DSA:1.20.1250.20 202 392 1.9E-20 T 15-10-2018 C2I28_02635 84f1185571a121c520f979cc6d7aafe2 90 Gene3D G3DSA:3.30.1320.10 1 90 1.5E-36 T 15-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02635 84f1185571a121c520f979cc6d7aafe2 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 5.2E-35 T 15-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02635 84f1185571a121c520f979cc6d7aafe2 90 SUPERFAMILY SSF54565 2 86 4.45E-34 T 15-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02635 84f1185571a121c520f979cc6d7aafe2 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 24.431 T 15-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_02635 84f1185571a121c520f979cc6d7aafe2 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 15-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_02635 84f1185571a121c520f979cc6d7aafe2 90 Pfam PF00886 Ribosomal protein S16 9 67 2.0E-25 T 15-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_25415 86693eda29715bd087c1f603a2a1d6a8 359 Gene3D G3DSA:1.25.40.290 123 236 6.2E-37 T 15-10-2018 C2I28_25415 86693eda29715bd087c1f603a2a1d6a8 359 Pfam PF08713 DNA alkylation repair enzyme 120 233 3.0E-5 T 15-10-2018 IPR014825 DNA alkylation repair enzyme C2I28_25415 86693eda29715bd087c1f603a2a1d6a8 359 SUPERFAMILY SSF48371 26 236 1.32E-44 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 SUPERFAMILY SSF50685 358 410 2.06E-10 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 SUPERFAMILY SSF54106 29 71 1.09E-11 T 15-10-2018 C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 Pfam PF01476 LysM domain 79 120 2.4E-13 T 15-10-2018 IPR018392 LysM domain C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 Pfam PF01476 LysM domain 30 71 6.6E-14 T 15-10-2018 IPR018392 LysM domain C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 SMART SM00257 78 121 2.6E-15 T 15-10-2018 IPR018392 LysM domain C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 SMART SM00257 29 72 3.2E-16 T 15-10-2018 IPR018392 LysM domain C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 Gene3D G3DSA:3.10.350.10 25 75 9.5E-19 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 Gene3D G3DSA:3.10.350.10 76 129 7.4E-19 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 SUPERFAMILY SSF54106 77 120 1.44E-11 T 15-10-2018 C2I28_10535 2a8356fa78b2d8b26c85604e41bd9d36 420 Pfam PF06725 3D domain 359 419 1.0E-21 T 15-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I28_14760 80464fbc3a53e23c5d6c8cb81bf85df5 36 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 14 33 1.1E-7 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_14760 80464fbc3a53e23c5d6c8cb81bf85df5 36 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 31 1.1E-6 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_27485 d75e5da2116d6d1a9d9d97f861b9ef39 363 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 357 1.4E-87 T 15-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 C2I28_27485 d75e5da2116d6d1a9d9d97f861b9ef39 363 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 356 1.7E-91 T 15-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 C2I28_27485 d75e5da2116d6d1a9d9d97f861b9ef39 363 SUPERFAMILY SSF53756 1 358 1.19E-99 T 15-10-2018 C2I28_27485 d75e5da2116d6d1a9d9d97f861b9ef39 363 Gene3D G3DSA:3.40.50.2000 186 327 9.0E-108 T 15-10-2018 C2I28_27485 d75e5da2116d6d1a9d9d97f861b9ef39 363 Gene3D G3DSA:3.40.50.2000 3 185 9.0E-108 T 15-10-2018 C2I28_04730 7ed5c1169d60059aad57129c0af74153 536 PIRSF PIRSF038958 20 535 5.1E-182 T 15-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I28_04730 7ed5c1169d60059aad57129c0af74153 536 Pfam PF01943 Polysaccharide biosynthesis protein 24 325 1.8E-56 T 15-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I28_04730 7ed5c1169d60059aad57129c0af74153 536 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 24 511 5.0E-180 T 15-10-2018 IPR014249 Sporulation stage V protein B C2I28_04730 7ed5c1169d60059aad57129c0af74153 536 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 378 518 8.5E-18 T 15-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I28_18285 3a1c3d13ee293e5d4768e51b403122a5 356 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 2.6E-131 T 15-10-2018 IPR025006 Protein of unknown function DUF3900 C2I28_18285 3a1c3d13ee293e5d4768e51b403122a5 356 Pfam PF13037 Domain of unknown function (DUF3898) 261 349 1.6E-40 T 15-10-2018 IPR025012 Domain of unknown function DUF3898 C2I28_15180 805e20b557a482edf7e5344c7c3b3584 183 PIRSF PIRSF021290 1 179 8.0E-73 T 15-10-2018 IPR010697 Protein of unknown function DUF1273 C2I28_15180 805e20b557a482edf7e5344c7c3b3584 183 Gene3D G3DSA:3.40.50.450 1 180 1.6E-69 T 15-10-2018 C2I28_15180 805e20b557a482edf7e5344c7c3b3584 183 Hamap MF_01575 UPF0398 protein . 1 177 36.363 T 15-10-2018 IPR010697 Protein of unknown function DUF1273 C2I28_15180 805e20b557a482edf7e5344c7c3b3584 183 SUPERFAMILY SSF102405 1 177 5.58E-64 T 15-10-2018 C2I28_15180 805e20b557a482edf7e5344c7c3b3584 183 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 6.3E-72 T 15-10-2018 IPR010697 Protein of unknown function DUF1273 C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 SUPERFAMILY SSF56281 11 423 2.16E-95 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 4.4E-17 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 Gene3D G3DSA:3.40.50.10710 207 357 4.7E-191 T 15-10-2018 C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 SMART SM00849 21 215 2.6E-25 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 Gene3D G3DSA:3.10.20.580 449 555 2.0E-39 T 15-10-2018 C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.726 T 15-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 361 407 5.4E-9 T 15-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 Gene3D G3DSA:3.60.15.10 12 442 4.7E-191 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 PIRSF PIRSF004803 1 555 2.5E-246 T 15-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 15-10-2018 IPR001587 Ribonuclease J, conserved site C2I28_14740 43e936610da36aa6df41e5cb097c5b0a 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 7.0E-229 T 15-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 C2I28_09960 c45769572ebd73eca8340c8a4b85d123 308 SUPERFAMILY SSF161111 22 221 1.83E-59 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_09960 c45769572ebd73eca8340c8a4b85d123 308 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 299 8.3E-94 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_09960 c45769572ebd73eca8340c8a4b85d123 308 Pfam PF01545 Cation efflux family 27 220 6.0E-50 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_09960 c45769572ebd73eca8340c8a4b85d123 308 SUPERFAMILY SSF160240 224 297 7.98E-9 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_09960 c45769572ebd73eca8340c8a4b85d123 308 Gene3D G3DSA:1.20.1510.10 23 220 8.9E-48 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_15935 3a34a5a4dfc1e54d7a1db2949da162d0 241 Gene3D G3DSA:1.10.3720.10 3 230 4.8E-51 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15935 3a34a5a4dfc1e54d7a1db2949da162d0 241 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 229 8.6E-16 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_15935 3a34a5a4dfc1e54d7a1db2949da162d0 241 SUPERFAMILY SSF161098 14 217 7.19E-41 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15935 3a34a5a4dfc1e54d7a1db2949da162d0 241 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 123 3.6E-23 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_19190 9ec3fcaad2c0aa9ee5b8b139785e54b8 370 Pfam PF03845 Spore germination protein 7 321 7.9E-44 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_19190 9ec3fcaad2c0aa9ee5b8b139785e54b8 370 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 364 6.2E-53 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 Gene3D G3DSA:1.10.150.520 16 92 2.5E-52 T 15-10-2018 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 Gene3D G3DSA:3.40.50.1000 3 213 2.5E-52 T 15-10-2018 IPR023214 HAD superfamily C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 191 1.7E-11 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 186 2.3E-12 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 SUPERFAMILY SSF56784 1 218 2.76E-47 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 2.0E-13 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 2.0E-13 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 2.0E-13 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.0E-13 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_21985 899b1e63d3056dbaac9d7647416b135a 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 191 2.9E-38 T 15-10-2018 C2I28_19705 461d00dda651cb99b04e78a4d000335a 72 Pfam PF10676 Spore germination protein gerPA/gerPF 5 60 1.9E-8 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_18160 d5ca54612b505744622503b7b54d3844 440 PIRSF PIRSF000337 3 439 1.6E-148 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_18160 d5ca54612b505744622503b7b54d3844 440 Pfam PF00296 Luciferase-like monooxygenase 22 383 6.2E-63 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_18160 d5ca54612b505744622503b7b54d3844 440 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 424 1.6E-170 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_18160 d5ca54612b505744622503b7b54d3844 440 SUPERFAMILY SSF51679 4 430 5.1E-135 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_18160 d5ca54612b505744622503b7b54d3844 440 Gene3D G3DSA:3.20.20.30 1 440 5.1E-162 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_23385 4d13556c165786a645fcb64b8cecec6d 301 Gene3D G3DSA:3.40.50.10330 12 129 8.6E-79 T 15-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 C2I28_23385 4d13556c165786a645fcb64b8cecec6d 301 SMART SM00046 9 136 6.4E-11 T 15-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I28_23385 4d13556c165786a645fcb64b8cecec6d 301 Pfam PF00781 Diacylglycerol kinase catalytic domain 10 131 1.5E-31 T 15-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 C2I28_23385 4d13556c165786a645fcb64b8cecec6d 301 SUPERFAMILY SSF111331 6 300 5.63E-67 T 15-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily C2I28_23385 4d13556c165786a645fcb64b8cecec6d 301 Gene3D G3DSA:2.60.200.40 130 284 8.6E-79 T 15-10-2018 C2I28_23385 4d13556c165786a645fcb64b8cecec6d 301 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 9 298 3.2E-66 T 15-10-2018 IPR005218 Diacylglycerol/lipid kinase C2I28_16435 6cc722d04033e2172d7e990aa5553886 740 SUPERFAMILY SSF82866 498 729 2.49E-26 T 15-10-2018 C2I28_16435 6cc722d04033e2172d7e990aa5553886 740 Pfam PF03176 MMPL family 502 729 7.3E-45 T 15-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I28_16435 6cc722d04033e2172d7e990aa5553886 740 Pfam PF03176 MMPL family 54 406 1.1E-61 T 15-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 C2I28_16435 6cc722d04033e2172d7e990aa5553886 740 Gene3D G3DSA:1.20.1640.10 194 363 3.7E-6 T 15-10-2018 C2I28_16435 6cc722d04033e2172d7e990aa5553886 740 SUPERFAMILY SSF82866 179 360 1.23E-28 T 15-10-2018 C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 307 2.4E-134 T 15-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 Gene3D G3DSA:3.40.50.1100 6 303 5.3E-118 T 15-10-2018 C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 SUPERFAMILY SSF53686 1 307 8.64E-99 T 15-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 15-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 296 6.9E-71 T 15-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 307 4.7E-126 T 15-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 C2I28_05750 70ab1141c6a68b7a762ea09108948f69 310 Gene3D G3DSA:3.40.50.1100 45 144 5.3E-118 T 15-10-2018 C2I28_24590 b73f012571adbd902bd6efb876645bce 258 Pfam PF01925 Sulfite exporter TauE/SafE 9 252 1.4E-43 T 15-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I28_08280 573837502fee12fcf57675ee1df6c1c2 248 SUPERFAMILY SSF53335 8 199 2.0E-32 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_08280 573837502fee12fcf57675ee1df6c1c2 248 Pfam PF05175 Methyltransferase small domain 19 134 1.2E-11 T 15-10-2018 IPR007848 Methyltransferase small domain GO:0008168 C2I28_08280 573837502fee12fcf57675ee1df6c1c2 248 Gene3D G3DSA:3.40.50.150 8 248 1.5E-70 T 15-10-2018 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 TIGRFAM TIGR01229 rocF_arginase: arginase 6 298 3.2E-110 T 15-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 SUPERFAMILY SSF52768 4 295 1.49E-93 T 15-10-2018 IPR023696 Ureohydrolase domain superfamily C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 PIRSF PIRSF036979 1 295 3.6E-38 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 ProSitePatterns PS01053 Arginase family signature. 224 245 - T 15-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 Pfam PF00491 Arginase family 4 294 5.6E-81 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 Gene3D G3DSA:3.40.800.10 2 299 1.2E-116 T 15-10-2018 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 PRINTS PR00116 Arginase signature 96 111 3.7E-43 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 PRINTS PR00116 Arginase signature 173 191 3.7E-43 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 PRINTS PR00116 Arginase signature 221 250 3.7E-43 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 PRINTS PR00116 Arginase signature 256 270 3.7E-43 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_01075 b9db9a01010ee07c616ade64002bc0d7 299 PRINTS PR00116 Arginase signature 119 146 3.7E-43 T 15-10-2018 IPR006035 Ureohydrolase GO:0046872 C2I28_06530 cab2b1593ff22dd1d5d626f68bf55e6c 435 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 426 1.2E-76 T 15-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 C2I28_06530 cab2b1593ff22dd1d5d626f68bf55e6c 435 Pfam PF01458 Uncharacterized protein family (UPF0051) 185 409 6.8E-62 T 15-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 C2I28_06530 cab2b1593ff22dd1d5d626f68bf55e6c 435 SUPERFAMILY SSF101960 13 434 5.62E-120 T 15-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily C2I28_19935 7a385853057d57cfc35057f2848456de 506 PIRSF PIRSF012702 1 500 1.2E-152 T 15-10-2018 IPR009197 Microcystin LR degradation protein MlrC C2I28_19935 7a385853057d57cfc35057f2848456de 506 Pfam PF07171 MlrC C-terminus 304 481 6.0E-46 T 15-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal C2I28_19935 7a385853057d57cfc35057f2848456de 506 Pfam PF07364 Metallopeptidase family M81 5 294 1.6E-91 T 15-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal C2I28_27320 ee2efe5c98169cafea12732c82b3369c 175 Gene3D G3DSA:3.40.50.300 2 148 7.7E-18 T 15-10-2018 C2I28_27320 ee2efe5c98169cafea12732c82b3369c 175 SUPERFAMILY SSF52540 3 140 8.74E-16 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_13670 6de843ed60d210be422fbc06061c3c96 409 Pfam PF01943 Polysaccharide biosynthesis protein 2 260 9.9E-14 T 15-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I28_13670 6de843ed60d210be422fbc06061c3c96 409 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 406 5.4E-9 T 15-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I28_01470 fdcb776e0c26896f06f83ddc91b692e2 312 Pfam PF00753 Metallo-beta-lactamase superfamily 50 209 4.4E-12 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_01470 fdcb776e0c26896f06f83ddc91b692e2 312 SMART SM00849 45 244 7.8E-15 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_01470 fdcb776e0c26896f06f83ddc91b692e2 312 SUPERFAMILY SSF56281 27 253 4.59E-34 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_13175 bf2b92c4c640631f3b6c228a6d7c7e1f 60 Gene3D G3DSA:1.10.1470.10 6 60 4.4E-9 T 15-10-2018 IPR036629 YjbJ superfamily C2I28_13175 bf2b92c4c640631f3b6c228a6d7c7e1f 60 Pfam PF05532 CsbD-like 7 57 2.5E-18 T 15-10-2018 IPR008462 CsbD-like domain C2I28_13175 bf2b92c4c640631f3b6c228a6d7c7e1f 60 SUPERFAMILY SSF69047 7 59 1.44E-11 T 15-10-2018 IPR036629 YjbJ superfamily C2I28_16765 1effa7fcd9cf5d707b29340ee2f5a02a 281 Pfam PF13714 Phosphoenolpyruvate phosphomutase 13 255 8.4E-73 T 15-10-2018 C2I28_16765 1effa7fcd9cf5d707b29340ee2f5a02a 281 SUPERFAMILY SSF51621 9 280 4.08E-62 T 15-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 C2I28_16765 1effa7fcd9cf5d707b29340ee2f5a02a 281 Gene3D G3DSA:3.20.20.60 2 252 3.8E-70 T 15-10-2018 C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.6E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.6E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.6E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 Pfam PF00106 short chain dehydrogenase 4 204 1.9E-39 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 Gene3D G3DSA:3.40.50.720 1 279 2.2E-77 T 15-10-2018 C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 SUPERFAMILY SSF51735 2 254 9.13E-58 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 2.5E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.5E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.5E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.5E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_22180 894cd099192ab7d424008da3ac9d4f08 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.5E-19 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_15850 a8ca89c46c9e71e751bd1fcb8851ffc6 528 SUPERFAMILY SSF52317 50 338 1.88E-10 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_01880 2597839d1aee4f397d0095d450246af1 429 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 6 340 1.9E-116 T 15-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase C2I28_01880 2597839d1aee4f397d0095d450246af1 429 SUPERFAMILY SSF51905 6 253 2.9E-15 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01880 2597839d1aee4f397d0095d450246af1 429 Gene3D G3DSA:3.50.50.60 1 426 1.9E-116 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_26750 88a108ca1a86700f683554de54a2cb5a 338 Gene3D G3DSA:3.40.1190.20 2 338 1.1E-98 T 15-10-2018 IPR029056 Ribokinase-like C2I28_26750 88a108ca1a86700f683554de54a2cb5a 338 SUPERFAMILY SSF53613 3 328 1.71E-60 T 15-10-2018 IPR029056 Ribokinase-like C2I28_26750 88a108ca1a86700f683554de54a2cb5a 338 Pfam PF00294 pfkB family carbohydrate kinase 4 318 1.7E-30 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_12340 07ddbee964326c6e7ee5e722d167a4d8 221 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 180 5.7E-70 T 15-10-2018 IPR022301 Integral membrane protein YjbE C2I28_12340 07ddbee964326c6e7ee5e722d167a4d8 221 Pfam PF03741 Integral membrane protein TerC family 11 179 4.7E-45 T 15-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 Gene3D G3DSA:3.40.50.300 12 444 7.2E-209 T 15-10-2018 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 Gene3D G3DSA:3.10.410.10 449 538 1.8E-36 T 15-10-2018 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 Gene3D G3DSA:3.30.1510.10 135 253 7.2E-209 T 15-10-2018 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 562 49.192 T 15-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 109 119 - T 15-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 SUPERFAMILY SSF52540 10 560 3.66E-249 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 334 345 - T 15-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I28_17730 0e3d1f62ccb1598969eb01720f8ad936 562 Pfam PF01268 Formate--tetrahydrofolate ligase 8 562 2.6E-274 T 15-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 C2I28_06550 180a737e3f9a4c1931824b9f76bc5d5e 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 222 4.3E-22 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_06550 180a737e3f9a4c1931824b9f76bc5d5e 222 Gene3D G3DSA:1.10.3720.10 9 222 2.3E-48 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_06550 180a737e3f9a4c1931824b9f76bc5d5e 222 SUPERFAMILY SSF161098 13 209 7.59E-46 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 Pfam PF02272 DHHA1 domain 260 387 1.2E-12 T 15-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 181 221 1.7E-9 T 15-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 SUPERFAMILY SSF55186 88 230 1.96E-35 T 15-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 Pfam PF01411 tRNA synthetases class II (A) 24 88 6.7E-8 T 15-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 Gene3D G3DSA:3.30.980.10 85 240 1.5E-47 T 15-10-2018 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 Gene3D G3DSA:3.10.310.40 286 390 1.4E-8 T 15-10-2018 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 Gene3D G3DSA:2.40.30.130 1 84 4.0E-27 T 15-10-2018 C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 SUPERFAMILY SSF50447 1 83 1.52E-17 T 15-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily C2I28_19395 d8d7b108658a0d02db237dc3efd03bc0 391 SMART SM00863 181 223 5.7E-12 T 15-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 C2I28_23390 d83e37722d6689854a434bf8946c8bf1 149 Pfam PF14154 Domain of unknown function (DUF4306) 2 78 8.5E-14 T 15-10-2018 IPR025440 Protein of unknown function DUF4306 C2I28_05140 dcc2ecfaab624bfcc5f0d34ced510c90 404 Gene3D G3DSA:1.20.1530.20 2 384 8.2E-66 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_05140 dcc2ecfaab624bfcc5f0d34ced510c90 404 Pfam PF00999 Sodium/hydrogen exchanger family 12 377 5.1E-62 T 15-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I28_13900 d348cd1ae3f11a7096d8655f4c1fe12c 214 Pfam PF00190 Cupin 41 165 3.3E-15 T 15-10-2018 IPR006045 Cupin 1 GO:0045735 C2I28_13900 d348cd1ae3f11a7096d8655f4c1fe12c 214 SMART SM00835 28 166 2.4E-24 T 15-10-2018 IPR006045 Cupin 1 GO:0045735 C2I28_13900 d348cd1ae3f11a7096d8655f4c1fe12c 214 SUPERFAMILY SSF51182 34 181 8.46E-27 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_13900 d348cd1ae3f11a7096d8655f4c1fe12c 214 Gene3D G3DSA:2.60.120.10 9 181 2.2E-38 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_04830 4cbbecb22f1ed4f6d58abcdc5b595742 149 Gene3D G3DSA:3.30.70.260 71 147 8.2E-6 T 15-10-2018 C2I28_04830 4cbbecb22f1ed4f6d58abcdc5b595742 149 PIRSF PIRSF025624 2 148 2.0E-58 T 15-10-2018 IPR008310 UPF0735 ACT domain-containing protein C2I28_04830 4cbbecb22f1ed4f6d58abcdc5b595742 149 Hamap MF_00707 UPF0735 ACT domain-containing protein . 4 148 31.695 T 15-10-2018 IPR008310 UPF0735 ACT domain-containing protein C2I28_04830 4cbbecb22f1ed4f6d58abcdc5b595742 149 SUPERFAMILY SSF55021 73 144 2.21E-9 T 15-10-2018 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 113 399 25.078 T 15-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 1.7E-33 T 15-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 1.5E-30 T 15-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Gene3D G3DSA:3.30.160.750 63 128 5.5E-15 T 15-10-2018 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 25.182 T 15-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Gene3D G3DSA:3.30.360.110 1 61 1.1E-18 T 15-10-2018 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Gene3D G3DSA:3.40.50.150 184 414 1.2E-57 T 15-10-2018 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 SUPERFAMILY SSF56276 5 113 3.22E-29 T 15-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 208 221 - T 15-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 SUPERFAMILY SSF53335 148 368 2.11E-52 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_22595 b5f935489590b4d4d0ccba1530cda6f7 425 Pfam PF01564 Spermine/spermidine synthase domain 187 364 8.2E-37 T 15-10-2018 C2I28_06635 863e2babad5915cd7581cef2ccda953f 328 SUPERFAMILY SSF53807 49 319 3.34E-68 T 15-10-2018 C2I28_06635 863e2babad5915cd7581cef2ccda953f 328 Gene3D G3DSA:3.40.50.1980 43 151 6.4E-35 T 15-10-2018 C2I28_06635 863e2babad5915cd7581cef2ccda953f 328 Gene3D G3DSA:3.40.50.1980 153 328 8.5E-66 T 15-10-2018 C2I28_06635 863e2babad5915cd7581cef2ccda953f 328 Pfam PF01497 Periplasmic binding protein 66 299 1.7E-31 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_17765 138adfec656ddcb13a58aa19a7141a38 145 Gene3D G3DSA:3.40.30.10 25 144 3.8E-50 T 15-10-2018 C2I28_17765 138adfec656ddcb13a58aa19a7141a38 145 Pfam PF06491 Disulphide isomerase 8 144 2.7E-59 T 15-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I28_17765 138adfec656ddcb13a58aa19a7141a38 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 8.7E-64 T 15-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I28_06940 224feccd078da6116f39de798ed60e88 175 SUPERFAMILY SSF51161 10 166 3.05E-33 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_06940 224feccd078da6116f39de798ed60e88 175 Gene3D G3DSA:2.160.10.10 42 173 7.9E-29 T 15-10-2018 C2I28_06940 224feccd078da6116f39de798ed60e88 175 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 140 6.0E-11 T 15-10-2018 IPR001451 Hexapeptide repeat C2I28_06940 224feccd078da6116f39de798ed60e88 175 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 115 143 - T 15-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 C2I28_05125 f3aae663d3d9ccf5f3f1752097d13588 284 SUPERFAMILY SSF161098 81 261 1.44E-33 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_05125 f3aae663d3d9ccf5f3f1752097d13588 284 Gene3D G3DSA:1.10.3720.10 75 273 1.8E-25 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_05125 f3aae663d3d9ccf5f3f1752097d13588 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 274 2.3E-33 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_26070 a24ae02460246ad9faba0b3b3d5b185c 247 Pfam PF12146 Serine aminopeptidase, S33 57 147 2.8E-10 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_26070 a24ae02460246ad9faba0b3b3d5b185c 247 SUPERFAMILY SSF53474 9 245 2.14E-27 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_26070 a24ae02460246ad9faba0b3b3d5b185c 247 Gene3D G3DSA:3.40.50.1820 13 245 1.2E-32 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_22400 c9409131d74014db4faaaa04034fdb97 219 SMART SM00702 39 213 4.4E-46 T 15-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 C2I28_22400 c9409131d74014db4faaaa04034fdb97 219 Gene3D G3DSA:2.60.120.620 20 214 1.7E-64 T 15-10-2018 C2I28_22400 c9409131d74014db4faaaa04034fdb97 219 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 115 213 5.7E-17 T 15-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 C2I28_21970 f304a2c2152bd38b2089e97e35115524 260 SUPERFAMILY SSF53335 14 253 6.69E-39 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_21970 f304a2c2152bd38b2089e97e35115524 260 Pfam PF13649 Methyltransferase domain 39 134 7.6E-21 T 15-10-2018 C2I28_21970 f304a2c2152bd38b2089e97e35115524 260 Gene3D G3DSA:2.20.25.570 142 212 1.7E-54 T 15-10-2018 C2I28_21970 f304a2c2152bd38b2089e97e35115524 260 Gene3D G3DSA:3.40.50.150 36 245 1.7E-54 T 15-10-2018 C2I28_09970 e90b56ff56863682354c8dcaaa79983f 151 Gene3D G3DSA:2.40.160.20 1 150 4.3E-51 T 15-10-2018 C2I28_09970 e90b56ff56863682354c8dcaaa79983f 151 Pfam PF11578 Protein of unknown function (DUF3237) 4 150 1.9E-38 T 15-10-2018 IPR020915 Uncharacterised protein family UPF0311 C2I28_09970 e90b56ff56863682354c8dcaaa79983f 151 Hamap MF_00775 UPF0311 protein . 4 151 23.858 T 15-10-2018 IPR020915 Uncharacterised protein family UPF0311 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 ProSitePatterns PS00760 Signal peptidases I lysine active site. 70 82 - T 15-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 Gene3D G3DSA:2.10.109.10 49 174 2.2E-46 T 15-10-2018 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 SUPERFAMILY SSF51306 15 174 1.0E-50 T 15-10-2018 IPR036286 LexA/Signal peptidase-like superfamily C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 1 168 1.5E-50 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 68 80 4.1E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 17 33 4.1E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 126 145 4.1E-22 T 15-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 ProSitePatterns PS00761 Signal peptidases I signature 3. 131 144 - T 15-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 Pfam PF00717 Peptidase S24-like 24 92 8.3E-19 T 15-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C C2I28_00025 e3fcdd37e7c1f57285cf24ddc0d4ef2b 175 ProSitePatterns PS00501 Signal peptidases I serine active site. 26 33 - T 15-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 SUPERFAMILY SSF53901 269 390 5.01E-42 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 SUPERFAMILY SSF53901 1 264 1.2E-73 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 Pfam PF02803 Thiolase, C-terminal domain 269 389 4.4E-48 T 15-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 PIRSF PIRSF000429 1 392 4.9E-130 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 3.0E-139 T 15-10-2018 IPR002155 Thiolase GO:0016747 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 Gene3D G3DSA:3.40.47.10 131 387 1.2E-147 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 Pfam PF00108 Thiolase, N-terminal domain 5 260 6.4E-76 T 15-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 15-10-2018 IPR020610 Thiolase, active site GO:0016747 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 15-10-2018 IPR020613 Thiolase, conserved site GO:0016747 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 Gene3D G3DSA:3.40.47.10 5 274 1.2E-147 T 15-10-2018 IPR016039 Thiolase-like GO:0003824 C2I28_06590 f3121783f2e23d114b8048c154eb272f 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 15-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 C2I28_15510 11f0fe0fcb563fc1f7d58fa62d9c6854 347 Pfam PF00487 Fatty acid desaturase 51 292 1.9E-35 T 15-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 15-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 346 1.2E-102 T 15-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 Pfam PF00270 DEAD/DEAH box helicase 20 148 2.3E-21 T 15-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 SUPERFAMILY SSF52540 56 342 3.58E-56 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 Gene3D G3DSA:3.40.50.300 1 197 3.6E-65 T 15-10-2018 C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 Pfam PF16124 RecQ zinc-binding 424 470 2.7E-7 T 15-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 Pfam PF00271 Helicase conserved C-terminal domain 225 321 1.5E-16 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 SMART SM00487 12 207 1.3E-31 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_03370 9eaa7e8ffeb8c7883f80ebfd059533ad 505 SMART SM00490 241 323 8.5E-22 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_09700 82902bdd52063a8d8b025029f4953544 197 SMART SM00014 58 167 3.3E-13 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_09700 82902bdd52063a8d8b025029f4953544 197 SUPERFAMILY SSF48317 10 174 6.8E-36 T 15-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily C2I28_09700 82902bdd52063a8d8b025029f4953544 197 Pfam PF01569 PAP2 superfamily 62 171 1.1E-18 T 15-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase C2I28_09700 82902bdd52063a8d8b025029f4953544 197 Gene3D G3DSA:1.20.144.10 88 195 5.2E-19 T 15-10-2018 C2I28_22060 9322db291a583b1438c6cdc3084e2731 118 Pfam PF05656 Protein of unknown function (DUF805) 11 114 2.6E-28 T 15-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 C2I28_19295 fab35d71051f9a67e9e7644c8b7a47a7 508 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 304 315 - T 15-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 C2I28_19295 fab35d71051f9a67e9e7644c8b7a47a7 508 Gene3D G3DSA:3.40.605.10 33 502 1.2E-179 T 15-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 C2I28_19295 fab35d71051f9a67e9e7644c8b7a47a7 508 SUPERFAMILY SSF53720 23 506 2.62E-163 T 15-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 C2I28_19295 fab35d71051f9a67e9e7644c8b7a47a7 508 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 275 282 - T 15-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 C2I28_19295 fab35d71051f9a67e9e7644c8b7a47a7 508 Gene3D G3DSA:3.40.309.10 280 474 1.2E-179 T 15-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 C2I28_19295 fab35d71051f9a67e9e7644c8b7a47a7 508 Pfam PF00171 Aldehyde dehydrogenase family 37 504 2.6E-171 T 15-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 C2I28_11050 7ae3a1be187e68f5898e3180115414d6 307 SUPERFAMILY SSF54534 141 239 6.07E-35 T 15-10-2018 C2I28_11050 7ae3a1be187e68f5898e3180115414d6 307 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 295 20.883 T 15-10-2018 IPR023059 Foldase protein PrsA GO:0003755 C2I28_11050 7ae3a1be187e68f5898e3180115414d6 307 Pfam PF13616 PPIC-type PPIASE domain 137 241 3.3E-31 T 15-10-2018 C2I28_11050 7ae3a1be187e68f5898e3180115414d6 307 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 178 199 - T 15-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 C2I28_11050 7ae3a1be187e68f5898e3180115414d6 307 SUPERFAMILY SSF109998 34 179 3.27E-20 T 15-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I28_11050 7ae3a1be187e68f5898e3180115414d6 307 Gene3D G3DSA:3.10.50.40 144 239 3.5E-40 T 15-10-2018 C2I28_09990 7c757f883d3a2f740c365172bebf439d 351 TIGRFAM TIGR00378 cax: calcium/proton exchanger 12 349 2.2E-147 T 15-10-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 C2I28_09990 7c757f883d3a2f740c365172bebf439d 351 Pfam PF01699 Sodium/calcium exchanger protein 28 179 2.5E-18 T 15-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 C2I28_09990 7c757f883d3a2f740c365172bebf439d 351 Pfam PF01699 Sodium/calcium exchanger protein 207 343 4.6E-19 T 15-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 C2I28_09990 7c757f883d3a2f740c365172bebf439d 351 Gene3D G3DSA:1.20.58.1130 35 238 2.0E-23 T 15-10-2018 C2I28_09990 7c757f883d3a2f740c365172bebf439d 351 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 3 348 6.3E-121 T 15-10-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_09990 7c757f883d3a2f740c365172bebf439d 351 Gene3D G3DSA:1.20.1420.30 58 342 2.0E-23 T 15-10-2018 C2I28_13070 e11d51776674f7c6abee262a0066df84 328 SUPERFAMILY SSF55347 127 291 4.25E-28 T 15-10-2018 C2I28_13070 e11d51776674f7c6abee262a0066df84 328 Gene3D G3DSA:3.30.360.10 134 327 1.4E-61 T 15-10-2018 C2I28_13070 e11d51776674f7c6abee262a0066df84 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 3.0E-27 T 15-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I28_13070 e11d51776674f7c6abee262a0066df84 328 Gene3D G3DSA:3.40.50.720 1 133 1.8E-39 T 15-10-2018 C2I28_13070 e11d51776674f7c6abee262a0066df84 328 SUPERFAMILY SSF51735 2 152 3.31E-46 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_21110 ce2bd19ec74a8948e0a7f5609feb1432 195 SMART SM00947 26 182 1.2E-36 T 15-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 C2I28_21110 ce2bd19ec74a8948e0a7f5609feb1432 195 SUPERFAMILY SSF53056 4 181 8.24E-40 T 15-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I28_21110 ce2bd19ec74a8948e0a7f5609feb1432 195 Gene3D G3DSA:3.40.1050.10 1 183 3.5E-46 T 15-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I28_21110 ce2bd19ec74a8948e0a7f5609feb1432 195 Pfam PF00484 Carbonic anhydrase 34 176 5.3E-17 T 15-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 C2I28_15260 e9b8e567f1910a46b1ebff5eb6047ed7 645 Pfam PF13307 Helicase C-terminal domain 490 638 1.9E-24 T 15-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I28_15260 e9b8e567f1910a46b1ebff5eb6047ed7 645 Gene3D G3DSA:3.40.50.300 37 309 3.9E-30 T 15-10-2018 C2I28_15260 e9b8e567f1910a46b1ebff5eb6047ed7 645 SMART SM00491 504 632 9.8E-7 T 15-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 C2I28_15260 e9b8e567f1910a46b1ebff5eb6047ed7 645 Gene3D G3DSA:3.40.50.300 462 641 5.7E-24 T 15-10-2018 C2I28_15260 e9b8e567f1910a46b1ebff5eb6047ed7 645 SUPERFAMILY SSF52540 51 624 1.04E-19 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15020 6f22f5445d388e13e8abb4ab438465e7 56 PIRSF PIRSF036698 1 56 9.4E-36 T 15-10-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA C2I28_15020 6f22f5445d388e13e8abb4ab438465e7 56 Pfam PF14084 Protein of unknown function (DUF4264) 5 56 1.2E-24 T 15-10-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA C2I28_21315 9dc051743668c737dc5524dc0e74a81d 189 Hamap MF_01986 Probable UbiX-like flavin prenyltransferase. 1 188 50.908 T 15-10-2018 IPR032901 Probable UbiX-like flavin prenyltransferase C2I28_21315 9dc051743668c737dc5524dc0e74a81d 189 SUPERFAMILY SSF52507 1 184 1.26E-64 T 15-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I28_21315 9dc051743668c737dc5524dc0e74a81d 189 Pfam PF02441 Flavoprotein 1 163 3.2E-28 T 15-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 C2I28_21315 9dc051743668c737dc5524dc0e74a81d 189 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 184 37.005 T 15-10-2018 IPR004507 Flavin prenyltransferase UbiX-like C2I28_21315 9dc051743668c737dc5524dc0e74a81d 189 Gene3D G3DSA:3.40.50.1950 1 189 1.8E-80 T 15-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 C2I28_21315 9dc051743668c737dc5524dc0e74a81d 189 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 182 1.3E-82 T 15-10-2018 IPR004507 Flavin prenyltransferase UbiX-like C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 SMART SM00387 301 411 1.3E-20 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 Gene3D G3DSA:3.30.565.10 262 412 5.4E-29 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 2.4E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 2.4E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 408 2.4E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 390 2.4E-11 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 410 1.6E-16 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_12190 58fc62cf90f37f8f40f71ba16a075d20 416 SUPERFAMILY SSF55874 268 409 1.57E-26 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_12460 59bba218cdba14143b46f13ce2f8b877 322 PIRSF PIRSF017082 1 321 8.6E-88 T 15-10-2018 IPR005064 Bordetella uptake gene GO:0030288 C2I28_12460 59bba218cdba14143b46f13ce2f8b877 322 Gene3D G3DSA:3.40.190.150 30 313 2.4E-59 T 15-10-2018 C2I28_12460 59bba218cdba14143b46f13ce2f8b877 322 SUPERFAMILY SSF53850 37 289 3.26E-8 T 15-10-2018 C2I28_12460 59bba218cdba14143b46f13ce2f8b877 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 59 314 1.8E-22 T 15-10-2018 IPR005064 Bordetella uptake gene GO:0030288 C2I28_12460 59bba218cdba14143b46f13ce2f8b877 322 Gene3D G3DSA:3.40.190.10 123 249 2.4E-59 T 15-10-2018 C2I28_17190 e192c2678b7a2381c3cfd9eca9be0e95 174 Gene3D G3DSA:1.20.120.450 1 171 3.7E-45 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_17190 e192c2678b7a2381c3cfd9eca9be0e95 174 SUPERFAMILY SSF109854 1 154 6.56E-28 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_17190 e192c2678b7a2381c3cfd9eca9be0e95 174 Pfam PF12867 DinB superfamily 12 150 5.5E-12 T 15-10-2018 IPR024775 DinB-like domain C2I28_24340 2e8b157a2c5c32cb1f73403a5dd325a5 49 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 20 43 3.2E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_26545 1c83a9ff8d20f3dc5922e04e1e2759a1 220 SUPERFAMILY SSF53335 15 208 3.11E-40 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_26545 1c83a9ff8d20f3dc5922e04e1e2759a1 220 Pfam PF13649 Methyltransferase domain 55 149 2.8E-23 T 15-10-2018 C2I28_26545 1c83a9ff8d20f3dc5922e04e1e2759a1 220 Gene3D G3DSA:3.40.50.150 14 210 2.0E-40 T 15-10-2018 C2I28_06475 94b6ab83392a9d4407d6df4d2af5f235 213 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 181 2.7E-25 T 15-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I28_21020 9da82dfe3bb58299eaf0e98d1cfcaa21 135 SUPERFAMILY SSF46785 22 132 7.31E-20 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21020 9da82dfe3bb58299eaf0e98d1cfcaa21 135 Gene3D G3DSA:1.10.10.10 6 134 1.1E-21 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_21020 9da82dfe3bb58299eaf0e98d1cfcaa21 135 SMART SM00347 18 118 8.2E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_21020 9da82dfe3bb58299eaf0e98d1cfcaa21 135 Pfam PF13463 Winged helix DNA-binding domain 26 91 4.8E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 SUPERFAMILY SSF57783 1 36 1.02E-14 T 15-10-2018 C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 Gene3D G3DSA:2.30.30.40 43 112 5.2E-35 T 15-10-2018 C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 2.6E-52 T 15-10-2018 IPR004624 PhnA protein C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 Pfam PF03831 PhnA domain 45 112 2.0E-34 T 15-10-2018 IPR013988 PhnA protein, C-terminal C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 Pfam PF08274 PhnA Zinc-Ribbon 4 30 1.7E-14 T 15-10-2018 IPR013987 PhnA protein, N-terminal C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 SUPERFAMILY SSF82057 40 112 1.37E-29 T 15-10-2018 C2I28_24470 8a86b882e9a8da3ad94971c45259b1fe 112 Gene3D G3DSA:2.20.25.10 1 41 2.5E-19 T 15-10-2018 C2I28_13085 63780f3ce32bfc801b73d42159bff0b6 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 195 5.0E-13 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_13085 63780f3ce32bfc801b73d42159bff0b6 203 SUPERFAMILY SSF88659 136 197 9.35E-15 T 15-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like C2I28_13085 63780f3ce32bfc801b73d42159bff0b6 203 Gene3D G3DSA:1.10.10.10 118 199 2.2E-12 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_13085 63780f3ce32bfc801b73d42159bff0b6 203 Pfam PF08281 Sigma-70, region 4 141 192 5.7E-11 T 15-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 C2I28_00825 3f08ffd118f5f262e32c7156c185609f 213 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 128 5.2E-16 T 15-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 C2I28_00825 3f08ffd118f5f262e32c7156c185609f 213 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 189 2.8E-75 T 15-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent C2I28_00825 3f08ffd118f5f262e32c7156c185609f 213 SUPERFAMILY SSF50475 29 178 7.03E-18 T 15-10-2018 C2I28_00825 3f08ffd118f5f262e32c7156c185609f 213 Gene3D G3DSA:2.30.110.10 28 154 2.8E-26 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_22185 171ecaf2d5a66d41674e6fbaffafb987 443 TIGRFAM TIGR00366 TIGR00366: TIGR00366 family protein 4 430 7.2E-183 T 15-10-2018 IPR006161 Conserved hypothetical protein CHP00336 C2I28_22185 171ecaf2d5a66d41674e6fbaffafb987 443 Pfam PF02667 Short chain fatty acid transporter 2 443 2.0E-186 T 15-10-2018 IPR006160 Short chain fatty acid transporter AtoE C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 Pfam PF06723 MreB/Mbl protein 4 328 7.0E-150 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 Gene3D G3DSA:3.90.640.10 178 251 1.9E-125 T 15-10-2018 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 SUPERFAMILY SSF53067 4 140 8.2E-39 T 15-10-2018 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 Gene3D G3DSA:3.30.420.40 146 309 1.9E-125 T 15-10-2018 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 4.1E-57 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 4.1E-57 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 4.1E-57 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 4.1E-57 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 4.1E-57 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 Gene3D G3DSA:3.30.420.40 6 319 1.9E-125 T 15-10-2018 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 3 328 1.1E-135 T 15-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 C2I28_07275 1a8b2cec646e2e0152a39c1d2923e036 333 SUPERFAMILY SSF53067 142 325 4.78E-49 T 15-10-2018 C2I28_24825 637f9bccfe0897005aa79cd7aa041c57 80 Pfam PF10676 Spore germination protein gerPA/gerPF 5 71 3.2E-12 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_04975 e94ae0b5b114d3028eae8f2cce4910fd 277 Pfam PF01578 Cytochrome C assembly protein 69 270 7.8E-33 T 15-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 C2I28_04945 a64c445ce5a6050fe2722c30bc6b6789 349 Gene3D G3DSA:3.90.1200.10 99 326 7.4E-22 T 15-10-2018 C2I28_04945 a64c445ce5a6050fe2722c30bc6b6789 349 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 8 315 2.7E-100 T 15-10-2018 IPR014253 Spore coat protein YsxE C2I28_04945 a64c445ce5a6050fe2722c30bc6b6789 349 SUPERFAMILY SSF56112 13 324 2.89E-14 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_04945 a64c445ce5a6050fe2722c30bc6b6789 349 Gene3D G3DSA:3.30.200.20 4 94 2.6E-15 T 15-10-2018 C2I28_13495 03b26430ef3690dd0b15555b158bb401 477 Gene3D G3DSA:1.20.1730.10 29 477 1.5E-85 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_13495 03b26430ef3690dd0b15555b158bb401 477 Pfam PF00474 Sodium:solute symporter family 42 413 1.6E-42 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_04200 9feed6d25a9a63ae8cb96ef865adae75 137 Gene3D G3DSA:1.10.10.10 1 83 7.4E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04200 9feed6d25a9a63ae8cb96ef865adae75 137 Pfam PF01475 Ferric uptake regulator family 13 129 1.0E-29 T 15-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 C2I28_04200 9feed6d25a9a63ae8cb96ef865adae75 137 Gene3D G3DSA:3.30.1490.190 85 136 1.2E-12 T 15-10-2018 C2I28_04200 9feed6d25a9a63ae8cb96ef865adae75 137 SUPERFAMILY SSF46785 5 132 1.58E-32 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25695 a0789daeb9a3dcd5e7dfc11c6f6aa985 280 Gene3D G3DSA:2.30.30.40 51 114 3.4E-10 T 15-10-2018 C2I28_25695 a0789daeb9a3dcd5e7dfc11c6f6aa985 280 Pfam PF00877 NlpC/P60 family 176 277 5.0E-29 T 15-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain C2I28_25695 a0789daeb9a3dcd5e7dfc11c6f6aa985 280 Gene3D G3DSA:3.90.1720.10 115 274 2.4E-39 T 15-10-2018 C2I28_25695 a0789daeb9a3dcd5e7dfc11c6f6aa985 280 SUPERFAMILY SSF54001 157 280 2.91E-37 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_27415 7eb0d9f317adcf051b7b910e97f2e76d 438 SUPERFAMILY SSF53448 211 431 1.81E-41 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_27415 7eb0d9f317adcf051b7b910e97f2e76d 438 Pfam PF00535 Glycosyl transferase family 2 215 348 4.6E-23 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_27415 7eb0d9f317adcf051b7b910e97f2e76d 438 Gene3D G3DSA:3.90.550.10 163 436 2.3E-41 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_26780 b0a64ccf3e21930d7b05c9ec29d57cd4 336 Gene3D G3DSA:1.50.10.10 25 326 7.6E-68 T 15-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 C2I28_26780 b0a64ccf3e21930d7b05c9ec29d57cd4 336 SUPERFAMILY SSF48208 13 316 1.25E-25 T 15-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 C2I28_07020 c9afed0fb420330c6e0eb0b12cde8458 296 Pfam PF02687 FtsX-like permease family 200 295 3.3E-7 T 15-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I28_07020 c9afed0fb420330c6e0eb0b12cde8458 296 PIRSF PIRSF003097 1 296 9.6E-86 T 15-10-2018 IPR004513 Cell division protein FtsX GO:0016021 C2I28_07020 c9afed0fb420330c6e0eb0b12cde8458 296 Gene3D G3DSA:3.30.70.3040 51 157 8.6E-7 T 15-10-2018 C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 Gene3D G3DSA:1.20.58.220 335 436 1.1E-14 T 15-10-2018 IPR038078 PhoU-like domain superfamily C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 Gene3D G3DSA:1.20.58.220 437 539 3.0E-21 T 15-10-2018 IPR038078 PhoU-like domain superfamily C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 Pfam PF01895 PhoU domain 341 427 6.3E-12 T 15-10-2018 IPR026022 PhoU domain C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 Pfam PF01895 PhoU domain 446 530 2.2E-17 T 15-10-2018 IPR026022 PhoU domain C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 3 308 2.1E-75 T 15-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 Pfam PF02690 Na+/Pi-cotransporter 140 251 6.9E-17 T 15-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 Pfam PF02690 Na+/Pi-cotransporter 11 146 4.5E-52 T 15-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 C2I28_04165 e4bf1036dee2ed50b183b898357dc732 544 SUPERFAMILY SSF109755 331 532 3.56E-48 T 15-10-2018 C2I28_10375 fdfb6bfc113cc7d32e631e4e44493ff6 363 Pfam PF03845 Spore germination protein 6 323 1.1E-60 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_10375 fdfb6bfc113cc7d32e631e4e44493ff6 363 PIRSF PIRSF006060 1 360 2.8E-14 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_10375 fdfb6bfc113cc7d32e631e4e44493ff6 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 357 9.3E-57 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_10375 fdfb6bfc113cc7d32e631e4e44493ff6 363 Gene3D G3DSA:1.20.1740.10 1 361 5.6E-14 T 15-10-2018 C2I28_11685 30d167d51d0989f01112de2d42cc330b 249 Hamap MF_01860 UPF0736 protein . 1 249 50.242 T 15-10-2018 IPR020909 UPF0736 C2I28_11685 30d167d51d0989f01112de2d42cc330b 249 Pfam PF12227 Protein of unknown function (DUF3603) 35 249 2.7E-111 T 15-10-2018 IPR020909 UPF0736 C2I28_05920 dcf80abd9fbead5bd7a44ba44529c4eb 190 SUPERFAMILY SSF53056 1 180 2.49E-42 T 15-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I28_05920 dcf80abd9fbead5bd7a44ba44529c4eb 190 Pfam PF00484 Carbonic anhydrase 34 177 4.6E-20 T 15-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 C2I28_05920 dcf80abd9fbead5bd7a44ba44529c4eb 190 Gene3D G3DSA:3.40.1050.10 2 182 1.4E-46 T 15-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 C2I28_05920 dcf80abd9fbead5bd7a44ba44529c4eb 190 SMART SM00947 26 181 1.6E-34 T 15-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 SUPERFAMILY SSF46689 236 285 9.86E-14 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 Pfam PF02311 AraC-like ligand binding domain 47 164 2.6E-11 T 15-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 SMART SM00342 200 283 9.9E-36 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 Pfam PF12833 Helix-turn-helix domain 206 284 8.9E-25 T 15-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 Gene3D G3DSA:1.10.10.60 185 233 2.2E-14 T 15-10-2018 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 Gene3D G3DSA:2.60.120.280 40 172 7.0E-7 T 15-10-2018 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 SUPERFAMILY SSF51215 53 169 1.7E-12 T 15-10-2018 IPR037923 Transcription regulator HTH-like C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 Gene3D G3DSA:1.10.10.60 234 288 8.9E-20 T 15-10-2018 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 SUPERFAMILY SSF46689 190 234 4.48E-10 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_11600 5137952208e35095bdce3e3dfe6f51c9 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 237 279 - T 15-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 C2I28_15085 e34a65a224a4f91e4297028eb53b218e 137 Pfam PF14179 YppG-like protein 2 135 8.6E-34 T 15-10-2018 IPR025555 YppG-like protein C2I28_07690 373596f4a4b3494832cc5ba2fbcf06df 111 Pfam PF00892 EamA-like transporter family 17 106 5.9E-7 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_07690 373596f4a4b3494832cc5ba2fbcf06df 111 SUPERFAMILY SSF103481 15 108 1.57E-11 T 15-10-2018 C2I28_07690 373596f4a4b3494832cc5ba2fbcf06df 111 Gene3D G3DSA:1.10.3730.20 10 110 1.8E-6 T 15-10-2018 C2I28_06510 46fc7bdd435d1c1c11326fe16d97b9ce 284 Gene3D G3DSA:3.20.20.410 1 281 5.1E-97 T 15-10-2018 IPR036520 UPF0759 superfamily C2I28_06510 46fc7bdd435d1c1c11326fe16d97b9ce 284 SUPERFAMILY SSF117396 1 268 4.84E-84 T 15-10-2018 IPR036520 UPF0759 superfamily C2I28_06510 46fc7bdd435d1c1c11326fe16d97b9ce 284 Pfam PF01904 Protein of unknown function DUF72 16 264 1.0E-61 T 15-10-2018 IPR002763 Protein of unknown function DUF72 C2I28_15345 77c36257cd934f368803fd6ffb1490d4 217 SUPERFAMILY SSF53098 73 209 9.11E-18 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_15345 77c36257cd934f368803fd6ffb1490d4 217 Pfam PF13456 Reverse transcriptase-like 78 205 8.7E-12 T 15-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 C2I28_15345 77c36257cd934f368803fd6ffb1490d4 217 Gene3D G3DSA:3.30.420.10 73 211 4.6E-26 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_04040 7637e8e0a9c147abc01c3fb4dbd3a2b2 127 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 115 1.2E-35 T 15-10-2018 IPR006504 Transcriptional regulator Spx/MgsR C2I28_04040 7637e8e0a9c147abc01c3fb4dbd3a2b2 127 SUPERFAMILY SSF52833 4 116 1.21E-32 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_04040 7637e8e0a9c147abc01c3fb4dbd3a2b2 127 Pfam PF03960 ArsC family 7 113 6.7E-21 T 15-10-2018 IPR006660 Arsenate reductase-like C2I28_04040 7637e8e0a9c147abc01c3fb4dbd3a2b2 127 Gene3D G3DSA:3.40.30.10 3 121 2.3E-37 T 15-10-2018 C2I28_08725 06274079f78247660a35799193303c37 66 Gene3D G3DSA:1.10.287.310 1 66 1.5E-30 T 15-10-2018 C2I28_08725 06274079f78247660a35799193303c37 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.0E-24 T 15-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08725 06274079f78247660a35799193303c37 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 15-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08725 06274079f78247660a35799193303c37 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.685 T 15-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08725 06274079f78247660a35799193303c37 66 SUPERFAMILY SSF46561 1 63 7.19E-24 T 15-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08725 06274079f78247660a35799193303c37 66 Pfam PF00831 Ribosomal L29 protein 4 60 4.3E-26 T 15-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_20260 076d83f1faacb258fc98354288e46a02 206 Pfam PF00293 NUDIX domain 27 135 6.9E-11 T 15-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 C2I28_20260 076d83f1faacb258fc98354288e46a02 206 SUPERFAMILY SSF55811 27 196 1.86E-28 T 15-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 C2I28_20260 076d83f1faacb258fc98354288e46a02 206 Gene3D G3DSA:3.90.79.10 1 202 1.7E-47 T 15-10-2018 C2I28_01110 b145f463d95e777dd1462ff40dfd8b49 152 SUPERFAMILY SSF69118 13 143 1.7E-15 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_01110 b145f463d95e777dd1462ff40dfd8b49 152 Gene3D G3DSA:1.20.1290.10 41 146 6.6E-12 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_15470 364a2850f356702a2c74e08b28013f01 261 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_15470 364a2850f356702a2c74e08b28013f01 261 Gene3D G3DSA:3.40.50.300 1 253 1.8E-69 T 15-10-2018 C2I28_15470 364a2850f356702a2c74e08b28013f01 261 SMART SM00382 28 217 2.6E-16 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_15470 364a2850f356702a2c74e08b28013f01 261 Pfam PF00005 ABC transporter 20 167 1.6E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_15470 364a2850f356702a2c74e08b28013f01 261 SUPERFAMILY SSF52540 4 230 3.09E-62 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_06970 3fbefe1516dbb6007934243dfbe522b2 363 PIRSF PIRSF012569 1 363 5.2E-95 T 15-10-2018 IPR016599 Uncharacterised conserved protein UCP012569 C2I28_06970 3fbefe1516dbb6007934243dfbe522b2 363 Pfam PF13349 Putative adhesin 109 332 2.7E-15 T 15-10-2018 IPR025164 Putative adhesin C2I28_09330 3b57eb6330c40e57fb28ca583691907f 75 Pfam PF14146 Domain of unknown function (DUF4305) 18 54 9.7E-18 T 15-10-2018 IPR025426 Protein of unknown function DUF4305 C2I28_09330 3b57eb6330c40e57fb28ca583691907f 75 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 65 2.0E-5 T 15-10-2018 C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 Gene3D G3DSA:3.30.565.10 278 429 3.5E-23 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 7.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 7.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 7.5E-9 T 15-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 SUPERFAMILY SSF55874 282 426 9.69E-25 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 SMART SM00387 317 429 1.1E-17 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_13410 6d2c8801ff40cd8b6f46a95555d7413d 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 324 427 2.5E-14 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_07245 0458a3a9d9ca4257dd3636cd46d031db 120 PIRSF PIRSF002070 1 120 5.7E-28 T 15-10-2018 C2I28_07245 0458a3a9d9ca4257dd3636cd46d031db 120 Pfam PF00436 Single-strand binding protein family 2 103 6.0E-29 T 15-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 C2I28_07245 0458a3a9d9ca4257dd3636cd46d031db 120 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 117 9.4E-31 T 15-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I28_07245 0458a3a9d9ca4257dd3636cd46d031db 120 SUPERFAMILY SSF50249 1 114 2.45E-35 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_07245 0458a3a9d9ca4257dd3636cd46d031db 120 Gene3D G3DSA:2.40.50.140 1 112 8.4E-38 T 15-10-2018 C2I28_07245 0458a3a9d9ca4257dd3636cd46d031db 120 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 27.3 T 15-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I28_12380 e3e8f4195b69eee4be0f4ad5a2fe93de 307 Pfam PF02424 ApbE family 8 279 2.0E-51 T 15-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 C2I28_12380 e3e8f4195b69eee4be0f4ad5a2fe93de 307 SUPERFAMILY SSF143631 2 288 2.46E-56 T 15-10-2018 IPR003374 ApbE-like superfamily C2I28_12380 e3e8f4195b69eee4be0f4ad5a2fe93de 307 PIRSF PIRSF006268 1 300 3.4E-46 T 15-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 C2I28_12380 e3e8f4195b69eee4be0f4ad5a2fe93de 307 Gene3D G3DSA:3.10.520.20 1 302 1.7E-60 T 15-10-2018 C2I28_01270 86f635ce6fefa268abc8b47b96326c8a 323 Pfam PF03060 Nitronate monooxygenase 3 308 4.7E-68 T 15-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 C2I28_01270 86f635ce6fefa268abc8b47b96326c8a 323 Gene3D G3DSA:3.20.20.70 1 320 5.0E-108 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_01270 86f635ce6fefa268abc8b47b96326c8a 323 SUPERFAMILY SSF51412 1 322 9.16E-68 T 15-10-2018 C2I28_07620 b181fadf2c4b94a22ac4c7ccba7631e0 148 Pfam PF12638 Staygreen protein 5 145 7.1E-21 T 15-10-2018 IPR024438 Staygreen protein C2I28_15310 20c9a47b8330ccb57d285ecbdcde9095 1205 SUPERFAMILY SSF52540 39 260 3.03E-32 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_15310 20c9a47b8330ccb57d285ecbdcde9095 1205 Gene3D G3DSA:3.40.50.300 51 282 1.7E-39 T 15-10-2018 C2I28_15310 20c9a47b8330ccb57d285ecbdcde9095 1205 Pfam PF00350 Dynamin family 630 851 1.6E-42 T 15-10-2018 IPR022812 Dynamin superfamily C2I28_15310 20c9a47b8330ccb57d285ecbdcde9095 1205 Pfam PF00350 Dynamin family 51 205 4.7E-26 T 15-10-2018 IPR022812 Dynamin superfamily C2I28_15310 20c9a47b8330ccb57d285ecbdcde9095 1205 SUPERFAMILY SSF52540 606 895 3.97E-35 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_17810 43f8bfce36bc87daa8a1e226fb8117e0 257 Pfam PF02654 Cobalamin-5-phosphate synthase 12 244 4.3E-46 T 15-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 C2I28_17810 43f8bfce36bc87daa8a1e226fb8117e0 257 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 8 242 2.1E-33 T 15-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 C2I28_17810 43f8bfce36bc87daa8a1e226fb8117e0 257 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 257 33.443 T 15-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 Pfam PF00710 Asparaginase, N-terminal 46 239 9.1E-60 T 15-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 SUPERFAMILY SSF53774 44 369 1.57E-99 T 15-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 PRINTS PR00139 Asparaginase/glutaminase family signature 306 324 8.5E-24 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 PRINTS PR00139 Asparaginase/glutaminase family signature 127 145 8.5E-24 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 PRINTS PR00139 Asparaginase/glutaminase family signature 47 58 8.5E-24 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 PIRSF PIRSF001220 41 370 5.2E-89 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 49 57 - T 15-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 Gene3D G3DSA:3.40.50.1170 41 258 7.4E-88 T 15-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 30 370 9.9E-151 T 15-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 PIRSF PIRSF500176 43 370 2.7E-75 T 15-10-2018 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 Gene3D G3DSA:3.40.50.40 259 370 3.1E-41 T 15-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 C2I28_00295 49bc9ac28e579a18337d78bb0e5392d4 370 SMART SM00870 46 364 9.2E-139 T 15-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 C2I28_01190 a904df85b94e24b3a21ca36791551969 248 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 13 229 4.7E-61 T 15-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 C2I28_01190 a904df85b94e24b3a21ca36791551969 248 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 226 3.4E-51 T 15-10-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 C2I28_07580 488384fe85e047fcdf01ddeb36674601 283 SUPERFAMILY SSF55681 7 271 2.07E-67 T 15-10-2018 C2I28_07580 488384fe85e047fcdf01ddeb36674601 283 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 7 279 49.812 T 15-10-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 C2I28_07580 488384fe85e047fcdf01ddeb36674601 283 Pfam PF03099 Biotin/lipoate A/B protein ligase family 79 185 1.1E-12 T 15-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I28_07580 488384fe85e047fcdf01ddeb36674601 283 Gene3D G3DSA:3.30.930.10 4 282 1.4E-80 T 15-10-2018 C2I28_22405 39da31c060ff49bc29c437d9bb772cf5 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 7.9E-241 T 15-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I28_22405 39da31c060ff49bc29c437d9bb772cf5 500 SUPERFAMILY SSF51905 7 274 3.37E-21 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22405 39da31c060ff49bc29c437d9bb772cf5 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 1.4E-220 T 15-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I28_22405 39da31c060ff49bc29c437d9bb772cf5 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.169 T 15-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 SUPERFAMILY SSF160996 193 361 1.7E-47 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 Gene3D G3DSA:2.40.30.10 192 360 1.7E-122 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 Gene3D G3DSA:1.10.8.260 279 343 1.7E-122 T 15-10-2018 IPR023166 HI0933-like insert domain superfamily C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 SUPERFAMILY SSF51905 1 415 1.77E-61 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 412 4.9E-143 T 15-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 Gene3D G3DSA:3.50.50.60 6 409 1.7E-122 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.9E-5 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.9E-5 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 Pfam PF03486 HI0933-like protein 3 413 1.1E-153 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.1E-10 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 2.1E-10 T 15-10-2018 C2I28_05780 c61e988c93f6eedeb446a7001baca691 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 2.1E-10 T 15-10-2018 C2I28_24725 6c428250b75bcd1e037876e974412265 108 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 3 83 3.9E-23 T 15-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 C2I28_24725 6c428250b75bcd1e037876e974412265 108 Gene3D G3DSA:1.10.10.10 1 107 2.7E-32 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24725 6c428250b75bcd1e037876e974412265 108 SUPERFAMILY SSF46767 3 84 9.03E-21 T 15-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.5E-19 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 Gene3D G3DSA:3.40.50.300 1 328 2.0E-101 T 15-10-2018 C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 SMART SM00382 33 241 5.0E-17 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 5.0E-14 T 15-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 Pfam PF00005 ABC transporter 25 183 2.0E-29 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_11715 f6220962cca6a9529f5286f28522ff76 356 SUPERFAMILY SSF52540 4 254 2.95E-73 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_18575 dc2db775253c69895dcf9c5868dc80cc 334 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 120 1.0E-30 T 15-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I28_18575 dc2db775253c69895dcf9c5868dc80cc 334 Gene3D G3DSA:3.40.50.720 4 314 1.4E-84 T 15-10-2018 C2I28_18575 dc2db775253c69895dcf9c5868dc80cc 334 SUPERFAMILY SSF55347 129 308 3.76E-23 T 15-10-2018 C2I28_18575 dc2db775253c69895dcf9c5868dc80cc 334 Gene3D G3DSA:3.30.360.10 125 330 1.4E-84 T 15-10-2018 C2I28_18575 dc2db775253c69895dcf9c5868dc80cc 334 SUPERFAMILY SSF51735 1 147 1.39E-46 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_18575 dc2db775253c69895dcf9c5868dc80cc 334 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 196 1.4E-7 T 15-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 C2I28_21895 ea089e361d2c62573e03d8628f0af195 108 Pfam PF14080 Domain of unknown function (DUF4261) 29 104 1.4E-8 T 15-10-2018 IPR025357 Domain of unknown function DUF4261 C2I28_10645 a53adbf5e6e8895140430dfea31899b4 162 Pfam PF06177 QueT transporter 7 153 2.4E-32 T 15-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 C2I28_10645 a53adbf5e6e8895140430dfea31899b4 162 PIRSF PIRSF031501 1 161 2.3E-58 T 15-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 SUPERFAMILY SSF47781 64 134 1.06E-19 T 15-10-2018 IPR010994 RuvA domain 2-like C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 4 201 1.9E-58 T 15-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 SUPERFAMILY SSF50249 1 61 4.4E-15 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 SMART SM00278 71 90 170.0 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 SMART SM00278 106 125 2.1 T 15-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Pfam PF01330 RuvA N terminal domain 2 60 6.6E-20 T 15-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Gene3D G3DSA:2.40.50.140 1 63 6.0E-17 T 15-10-2018 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 SUPERFAMILY SSF46929 155 200 3.66E-11 T 15-10-2018 IPR036267 RuvA, C-terminal domain superfamily C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Gene3D G3DSA:1.10.8.10 153 200 2.5E-9 T 15-10-2018 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 30.37 T 15-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Gene3D G3DSA:1.10.150.20 65 138 1.7E-23 T 15-10-2018 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Pfam PF07499 RuvA, C-terminal domain 157 200 4.6E-13 T 15-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 C2I28_04770 dbe1fd6f9ac0577c232bfb775c11ca3f 203 Pfam PF14520 Helix-hairpin-helix domain 70 127 5.1E-14 T 15-10-2018 C2I28_14735 b31957e7b720e8541f0863777bdec8f0 220 Gene3D G3DSA:3.40.50.720 1 137 5.5E-38 T 15-10-2018 C2I28_14735 b31957e7b720e8541f0863777bdec8f0 220 SUPERFAMILY SSF51735 4 134 3.61E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_14735 b31957e7b720e8541f0863777bdec8f0 220 Pfam PF02080 TrkA-C domain 150 217 9.2E-17 T 15-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I28_14735 b31957e7b720e8541f0863777bdec8f0 220 Gene3D G3DSA:3.30.70.1450 138 217 4.6E-28 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_14735 b31957e7b720e8541f0863777bdec8f0 220 SUPERFAMILY SSF116726 131 217 2.09E-21 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_14735 b31957e7b720e8541f0863777bdec8f0 220 Pfam PF02254 TrkA-N domain 5 120 3.8E-29 T 15-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 C2I28_17170 22decd789f1ce439df8669afa61441a5 300 Pfam PF03547 Membrane transport protein 4 138 1.1E-6 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_17170 22decd789f1ce439df8669afa61441a5 300 Pfam PF03547 Membrane transport protein 155 295 1.4E-15 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_17170 22decd789f1ce439df8669afa61441a5 300 Gene3D G3DSA:1.20.1530.20 150 300 1.5E-6 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.2E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.2E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.2E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.2E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.2E-14 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 SUPERFAMILY SSF51735 2 226 7.9E-41 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.3E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.3E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.3E-7 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 Gene3D G3DSA:3.40.50.720 1 238 5.8E-40 T 15-10-2018 C2I28_16910 a78c00003ec993ddcc1e00d231a183e0 249 Pfam PF00106 short chain dehydrogenase 3 195 4.1E-33 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_07080 cb748986235d02ed551139f54bbd00f5 133 PIRSF PIRSF039090 1 128 1.5E-34 T 15-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I28_07080 cb748986235d02ed551139f54bbd00f5 133 Pfam PF02561 Flagellar protein FliS 7 118 3.4E-38 T 15-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I28_07080 cb748986235d02ed551139f54bbd00f5 133 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 120 2.4E-41 T 15-10-2018 IPR003713 Flagellar protein FliS GO:0044780 C2I28_07080 cb748986235d02ed551139f54bbd00f5 133 Gene3D G3DSA:1.20.120.340 1 121 4.5E-39 T 15-10-2018 C2I28_07080 cb748986235d02ed551139f54bbd00f5 133 SUPERFAMILY SSF101116 4 123 1.57E-37 T 15-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 C2I28_24275 0484de44e75b1315e6e72aeb56a660fd 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 120 5.3E-9 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_24275 0484de44e75b1315e6e72aeb56a660fd 129 SUPERFAMILY SSF54593 1 126 8.19E-21 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_24275 0484de44e75b1315e6e72aeb56a660fd 129 Gene3D G3DSA:3.10.180.10 1 125 1.2E-25 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 SMART SM01374 1 122 1.0E-84 T 15-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 SUPERFAMILY SSF50193 1 122 4.45E-50 T 15-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.8E-58 T 15-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 Gene3D G3DSA:2.40.150.20 1 122 2.4E-53 T 15-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 6.3E-54 T 15-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 15-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08735 8eada0b75c72827fa03b28cb9aa01aaa 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.814 T 15-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 C2I28_09555 1dd4d698fed1fea8d9f9afb253ac65d9 120 Gene3D G3DSA:3.40.1580.10 1 120 1.0E-13 T 15-10-2018 IPR037883 Knr4/Smi1-like domain superfamily C2I28_09555 1dd4d698fed1fea8d9f9afb253ac65d9 120 Pfam PF14568 SMI1-KNR4 cell-wall 2 113 1.8E-11 T 15-10-2018 C2I28_09555 1dd4d698fed1fea8d9f9afb253ac65d9 120 SUPERFAMILY SSF160631 2 119 4.58E-11 T 15-10-2018 C2I28_00930 eb5e08565143403c87ca271a879df8df 223 Gene3D G3DSA:1.10.10.10 121 223 5.5E-26 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00930 eb5e08565143403c87ca271a879df8df 223 Gene3D G3DSA:3.40.50.2300 1 120 5.0E-31 T 15-10-2018 C2I28_00930 eb5e08565143403c87ca271a879df8df 223 SMART SM00862 147 222 8.5E-20 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_00930 eb5e08565143403c87ca271a879df8df 223 Pfam PF00072 Response regulator receiver domain 3 111 4.7E-24 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_00930 eb5e08565143403c87ca271a879df8df 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 3.7E-23 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_00930 eb5e08565143403c87ca271a879df8df 223 SUPERFAMILY SSF46894 126 221 1.13E-24 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_00930 eb5e08565143403c87ca271a879df8df 223 SUPERFAMILY SSF52172 1 123 2.13E-35 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_00930 eb5e08565143403c87ca271a879df8df 223 SMART SM00448 1 111 5.8E-32 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 SUPERFAMILY SSF51430 5 267 2.23E-80 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 Pfam PF00248 Aldo/keto reductase family 206 267 4.0E-5 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 Pfam PF00248 Aldo/keto reductase family 17 206 8.2E-40 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 PIRSF PIRSF000097 1 279 2.3E-71 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 - T 15-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 Gene3D G3DSA:3.20.20.100 1 277 1.0E-94 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 PRINTS PR00069 Aldo-keto reductase signature 36 60 8.8E-39 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 PRINTS PR00069 Aldo-keto reductase signature 92 110 8.8E-39 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 PRINTS PR00069 Aldo-keto reductase signature 133 150 8.8E-39 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 PRINTS PR00069 Aldo-keto reductase signature 167 196 8.8E-39 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_00385 287350752a9595d866ad0d04bb6b663e 287 PRINTS PR00069 Aldo-keto reductase signature 204 228 8.8E-39 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_09820 06aff1a76a482f537c5d16b71b8def58 79 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 78 9.2E-12 T 15-10-2018 IPR024962 YukD-like C2I28_09820 06aff1a76a482f537c5d16b71b8def58 79 PIRSF PIRSF037793 1 79 3.1E-29 T 15-10-2018 IPR014921 EsaB C2I28_09820 06aff1a76a482f537c5d16b71b8def58 79 Gene3D G3DSA:3.10.20.90 1 79 2.5E-36 T 15-10-2018 C2I28_20795 a05f00310b310753684b983883bfd272 202 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 20 197 2.1E-58 T 15-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 C2I28_20795 a05f00310b310753684b983883bfd272 202 Gene3D G3DSA:1.10.1760.20 17 198 8.7E-52 T 15-10-2018 C2I28_20795 a05f00310b310753684b983883bfd272 202 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 21 194 1.3E-59 T 15-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 C2I28_10795 37128672dfc97123feb3804c769e79c2 256 Gene3D G3DSA:2.40.440.10 21 214 1.3E-44 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_10795 37128672dfc97123feb3804c769e79c2 256 SUPERFAMILY SSF141523 28 153 1.05E-33 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_10795 37128672dfc97123feb3804c769e79c2 256 Pfam PF03734 L,D-transpeptidase catalytic domain 30 153 6.5E-26 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_26530 f6f62111014fdefea2805db399ba3954 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 5.2E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_26530 f6f62111014fdefea2805db399ba3954 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 5.2E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_26530 f6f62111014fdefea2805db399ba3954 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 5.2E-9 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_26530 f6f62111014fdefea2805db399ba3954 252 SUPERFAMILY SSF53474 2 252 1.89E-40 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_26530 f6f62111014fdefea2805db399ba3954 252 Gene3D G3DSA:3.40.50.1820 9 250 5.5E-41 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_26530 f6f62111014fdefea2805db399ba3954 252 Pfam PF00561 alpha/beta hydrolase fold 28 138 6.2E-18 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_12745 f7da70d1b9b56d58f579a856de372c07 316 Gene3D G3DSA:2.60.120.10 228 316 2.0E-25 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_12745 f7da70d1b9b56d58f579a856de372c07 316 SUPERFAMILY SSF51182 2 315 4.07E-104 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_12745 f7da70d1b9b56d58f579a856de372c07 316 Gene3D G3DSA:2.60.120.10 1 227 1.3E-93 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_12745 f7da70d1b9b56d58f579a856de372c07 316 PIRSF PIRSF036894 3 316 1.2E-127 T 15-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 C2I28_12745 f7da70d1b9b56d58f579a856de372c07 316 Pfam PF01238 Phosphomannose isomerase type I 8 200 1.4E-41 T 15-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 C2I28_12745 f7da70d1b9b56d58f579a856de372c07 316 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 102 315 3.0E-50 T 15-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 C2I28_11120 ceb7682ee3685707e71a4318d4819854 401 PIRSF PIRSF037259 2 401 2.1E-121 T 15-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I28_11120 ceb7682ee3685707e71a4318d4819854 401 Pfam PF05975 Bacterial ABC transporter protein EcsB 6 375 5.0E-123 T 15-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 Gene3D G3DSA:3.40.50.720 1 187 2.2E-60 T 15-10-2018 C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 186 2.9E-56 T 15-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 Gene3D G3DSA:1.10.1040.10 193 294 3.2E-33 T 15-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 SUPERFAMILY SSF51735 6 188 1.29E-52 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 287 1.8E-30 T 15-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 SUPERFAMILY SSF48179 191 291 1.79E-26 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_19845 0ddcc5877ec6fa0fb5a04ebb9c094263 294 PIRSF PIRSF000105 1 294 4.0E-90 T 15-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 C2I28_24575 df3eb048be4b7d9d4bf17754283724e7 400 Pfam PF00155 Aminotransferase class I and II 55 383 1.8E-36 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_24575 df3eb048be4b7d9d4bf17754283724e7 400 Gene3D G3DSA:3.90.1150.10 15 387 7.7E-142 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_24575 df3eb048be4b7d9d4bf17754283724e7 400 Gene3D G3DSA:3.40.640.10 64 284 7.7E-142 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_24575 df3eb048be4b7d9d4bf17754283724e7 400 SUPERFAMILY SSF53383 4 390 3.03E-111 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_12930 d24bd87d978c7c8f665c6e49623636c5 441 PIRSF PIRSF005353 1 441 1.6E-170 T 15-10-2018 IPR026033 Purine permease PbuG-like C2I28_12930 d24bd87d978c7c8f665c6e49623636c5 441 Pfam PF00860 Permease family 22 399 7.6E-53 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_09505 b5d0ba8c4a172f7be265933d0e13a5ea 232 SUPERFAMILY SSF51395 4 217 5.31E-54 T 15-10-2018 C2I28_09505 b5d0ba8c4a172f7be265933d0e13a5ea 232 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.939 T 15-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 C2I28_09505 b5d0ba8c4a172f7be265933d0e13a5ea 232 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 8 223 1.2E-78 T 15-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 C2I28_09505 b5d0ba8c4a172f7be265933d0e13a5ea 232 Gene3D G3DSA:3.20.20.390 1 230 3.0E-96 T 15-10-2018 IPR038597 GGGP/HepGP synthase superfamily C2I28_09505 b5d0ba8c4a172f7be265933d0e13a5ea 232 Pfam PF01884 PcrB family 2 226 1.6E-83 T 15-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 C2I28_09615 c2fa679694e3688dfde8de432ca96937 265 Gene3D G3DSA:1.10.238.10 93 249 2.2E-5 T 15-10-2018 C2I28_12855 8dafc3bb3dec5be37f9797443af79a24 171 Gene3D G3DSA:3.40.630.30 6 166 2.2E-5 T 15-10-2018 C2I28_12855 8dafc3bb3dec5be37f9797443af79a24 171 SUPERFAMILY SSF55729 103 154 1.29E-5 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22845 8474ed3fdf3cb3f1de9a23bbb1b06f12 215 SUPERFAMILY SSF55469 20 214 4.19E-72 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_22845 8474ed3fdf3cb3f1de9a23bbb1b06f12 215 Gene3D G3DSA:3.40.109.10 19 215 2.6E-90 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_22845 8474ed3fdf3cb3f1de9a23bbb1b06f12 215 Pfam PF00881 Nitroreductase family 25 193 3.8E-18 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_23300 ecd4156568d5140ad8e91a4eeab7cc76 94 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 4.6E-20 T 15-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain C2I28_23300 ecd4156568d5140ad8e91a4eeab7cc76 94 SUPERFAMILY SSF54909 1 79 2.2E-24 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_23300 ecd4156568d5140ad8e91a4eeab7cc76 94 Gene3D G3DSA:3.30.70.100 1 94 2.4E-26 T 15-10-2018 C2I28_24815 6fefe19b98b6b7c7f56d1f67c49f1291 206 Gene3D G3DSA:3.20.20.370 1 202 3.2E-72 T 15-10-2018 C2I28_24815 6fefe19b98b6b7c7f56d1f67c49f1291 206 Pfam PF01522 Polysaccharide deacetylase 3 122 2.0E-38 T 15-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 C2I28_24815 6fefe19b98b6b7c7f56d1f67c49f1291 206 SUPERFAMILY SSF88713 4 197 1.39E-63 T 15-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 C2I28_20005 1923cc91847911faff412724e8c81269 433 SUPERFAMILY SSF53383 34 421 2.75E-64 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_20005 1923cc91847911faff412724e8c81269 433 Gene3D G3DSA:3.40.640.10 4 425 7.0E-111 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_20005 1923cc91847911faff412724e8c81269 433 Pfam PF00155 Aminotransferase class I and II 37 412 1.2E-34 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 Gene3D G3DSA:3.30.70.150 1 121 4.1E-31 T 15-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 Gene3D G3DSA:3.20.20.110 122 413 1.1E-101 T 15-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 127 407 8.3E-44 T 15-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 408 8.7E-218 T 15-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 SUPERFAMILY SSF54966 1 121 2.09E-31 T 15-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 408 59.871 T 15-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 115 1.2E-6 T 15-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I28_14300 996a46a3f04eafb3192844955fe4293a 414 SUPERFAMILY SSF51649 122 409 1.02E-88 T 15-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 C2I28_23305 a6139f194a6380379946fb4d6b10fbe3 245 PIRSF PIRSF005426 1 245 1.3E-88 T 15-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 C2I28_23305 a6139f194a6380379946fb4d6b10fbe3 245 Gene3D G3DSA:3.40.109.10 1 245 4.4E-82 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_23305 a6139f194a6380379946fb4d6b10fbe3 245 SUPERFAMILY SSF55469 1 244 7.2E-67 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_23305 a6139f194a6380379946fb4d6b10fbe3 245 Pfam PF00881 Nitroreductase family 8 164 7.3E-22 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_20815 762c8bdf27400d8d0e63d03ad1f7a426 194 Gene3D G3DSA:3.40.50.850 1 190 4.0E-59 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_20815 762c8bdf27400d8d0e63d03ad1f7a426 194 SUPERFAMILY SSF52499 3 186 1.16E-51 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_20815 762c8bdf27400d8d0e63d03ad1f7a426 194 Pfam PF00857 Isochorismatase family 7 179 3.5E-35 T 15-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I28_17655 55c4a751a0cd2f8e624a94cf74502d69 42 Pfam PF14115 YuzL-like protein 3 41 1.7E-15 T 15-10-2018 IPR025625 YuzL-like protein C2I28_19630 ef6a17b1b5b83909560ccad0f50d978b 497 Gene3D G3DSA:1.20.1730.10 20 491 1.1E-25 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_19630 ef6a17b1b5b83909560ccad0f50d978b 497 Pfam PF00474 Sodium:solute symporter family 35 428 1.6E-19 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_09980 d14f150e02820f751c8cdee7ebdb567b 127 Gene3D G3DSA:3.30.300.20 1 127 2.0E-26 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_09980 d14f150e02820f751c8cdee7ebdb567b 127 Pfam PF02566 OsmC-like protein 27 121 6.2E-18 T 15-10-2018 IPR003718 OsmC/Ohr family C2I28_09980 d14f150e02820f751c8cdee7ebdb567b 127 SUPERFAMILY SSF82784 8 126 6.54E-24 T 15-10-2018 IPR036102 OsmC/Ohr superfamily C2I28_01215 817d0d813bc464a628e0227d921134e9 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 1.3E-12 T 15-10-2018 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.3E-12 T 15-10-2018 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 303 327 1.3E-12 T 15-10-2018 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.3E-12 T 15-10-2018 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 Gene3D G3DSA:1.20.1720.10 15 223 5.4E-40 T 15-10-2018 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 SUPERFAMILY SSF103473 8 492 1.83E-65 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_01215 817d0d813bc464a628e0227d921134e9 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 486 1.4E-129 T 15-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 Pfam PF07690 Major Facilitator Superfamily 19 410 3.2E-51 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_01215 817d0d813bc464a628e0227d921134e9 509 Gene3D G3DSA:1.20.1250.20 261 502 3.0E-20 T 15-10-2018 C2I28_21870 9fd588b366bf9813fc5c44fc9c7e1864 155 Pfam PF09406 Protein of unknown function (DUF2004) 61 152 7.7E-11 T 15-10-2018 IPR018546 Protein of unknown function DUF2004 C2I28_00835 608bb8f5b042c538da6483ad9a6318a5 172 Pfam PF00583 Acetyltransferase (GNAT) family 32 138 1.9E-19 T 15-10-2018 IPR000182 GNAT domain C2I28_00835 608bb8f5b042c538da6483ad9a6318a5 172 PIRSF PIRSF037663 2 172 1.9E-14 T 15-10-2018 IPR017255 Acetyltransferase, GNAT, predicted C2I28_00835 608bb8f5b042c538da6483ad9a6318a5 172 SUPERFAMILY SSF55729 2 164 5.15E-34 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_00835 608bb8f5b042c538da6483ad9a6318a5 172 Gene3D G3DSA:3.40.630.30 1 164 1.6E-40 T 15-10-2018 C2I28_22495 ac1544e3208d72135f1e5c98ecef8714 566 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 16 557 1.9E-186 T 15-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I28_22495 ac1544e3208d72135f1e5c98ecef8714 566 Pfam PF02652 L-lactate permease 17 557 5.8E-205 T 15-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 C2I28_10870 10a7efdf23c4d809e5d424999ea8ae97 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 228 2.3E-25 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_10870 10a7efdf23c4d809e5d424999ea8ae97 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 26 123 7.0E-29 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_10870 10a7efdf23c4d809e5d424999ea8ae97 234 SUPERFAMILY SSF161098 28 214 1.7E-46 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_10870 10a7efdf23c4d809e5d424999ea8ae97 234 Gene3D G3DSA:1.10.3720.10 21 231 1.4E-53 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_23425 8a75b4d7a06ddb8453ee3ebe387e6583 277 SUPERFAMILY SSF52091 166 276 1.06E-14 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_23425 8a75b4d7a06ddb8453ee3ebe387e6583 277 Pfam PF01740 STAS domain 174 266 3.1E-10 T 15-10-2018 IPR002645 STAS domain C2I28_23425 8a75b4d7a06ddb8453ee3ebe387e6583 277 Gene3D G3DSA:3.30.750.24 163 277 1.8E-32 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_05510 463031dda70cb6d4071f892caae83e95 280 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 11 275 9.0E-8 T 15-10-2018 C2I28_05510 463031dda70cb6d4071f892caae83e95 280 Pfam PF12787 EcsC protein family 9 272 1.4E-45 T 15-10-2018 IPR024787 EcsC protein C2I28_21960 5a741e0ce4167148701a44a020dc14b7 251 ProDom PD315856 ORF119 CPE0798 YOXB 22 245 1.0E-59 T 15-10-2018 IPR020530 Uncharacterised protein family, YoxB C2I28_12935 91078d0805468249638955b1fa1c9da7 183 PRINTS PR01100 Shikimate kinase family signature 83 92 2.1E-16 T 15-10-2018 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 PRINTS PR01100 Shikimate kinase family signature 37 50 2.1E-16 T 15-10-2018 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 PRINTS PR01100 Shikimate kinase family signature 104 121 2.1E-16 T 15-10-2018 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 PRINTS PR01100 Shikimate kinase family signature 13 28 2.1E-16 T 15-10-2018 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 PRINTS PR01100 Shikimate kinase family signature 65 73 2.1E-16 T 15-10-2018 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 ProSitePatterns PS01128 Shikimate kinase signature. 66 91 - T 15-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 SUPERFAMILY SSF52540 11 175 3.15E-23 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12935 91078d0805468249638955b1fa1c9da7 183 Gene3D G3DSA:3.40.50.300 8 181 3.4E-44 T 15-10-2018 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 Hamap MF_00109 Shikimate kinase [aroK]. 10 175 23.978 T 15-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 C2I28_12935 91078d0805468249638955b1fa1c9da7 183 Pfam PF01202 Shikimate kinase 19 174 3.7E-44 T 15-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 C2I28_20875 9b3a2c819d83256331ac3b217a8e611e 80 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 78 28.664 T 15-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like C2I28_20875 9b3a2c819d83256331ac3b217a8e611e 80 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 6 72 1.0E-27 T 15-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like C2I28_09335 15af6afbbba043c0812d249a6b60025b 242 Pfam PF02517 CAAX protease self-immunity 125 210 2.6E-16 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_13595 567a58240fa9fe24e9df5bc8f0e2e469 234 Pfam PF06149 Protein of unknown function (DUF969) 1 216 1.5E-86 T 15-10-2018 IPR010374 Protein of unknown function DUF969 C2I28_13425 d9e67c272f6cdcdb390e63858b671956 59 Pfam PF14151 YfhD-like protein 1 49 2.4E-13 T 15-10-2018 IPR025435 YfhD-like protein C2I28_19110 4dd3a9f5214301630617fad5c350090a 403 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 11 399 5.8E-94 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_19110 4dd3a9f5214301630617fad5c350090a 403 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 230 397 3.3E-35 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_19110 4dd3a9f5214301630617fad5c350090a 403 Gene3D G3DSA:3.30.300.210 246 401 7.3E-43 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_01320 03a7ca21d0ff9aaa091ac949cbf0cb8a 61 Pfam PF13076 Fur-regulated basic protein A 13 46 4.3E-14 T 15-10-2018 IPR025072 Fur-regulated basic protein A C2I28_19030 823258adc497a0c2ae78d748d08f90e5 182 SUPERFAMILY SSF52499 2 181 6.02E-48 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_19030 823258adc497a0c2ae78d748d08f90e5 182 Gene3D G3DSA:3.40.50.850 1 182 1.8E-51 T 15-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 C2I28_19030 823258adc497a0c2ae78d748d08f90e5 182 Pfam PF00857 Isochorismatase family 4 177 4.1E-35 T 15-10-2018 IPR000868 Isochorismatase-like GO:0003824 C2I28_04055 14d82cb99c8f2d75a674bd35f5bc1ad7 58 Pfam PF10958 Protein of unknown function (DUF2759) 6 55 1.6E-24 T 15-10-2018 IPR024490 Protein of unknown function DUF2759 C2I28_04055 14d82cb99c8f2d75a674bd35f5bc1ad7 58 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 1 54 1.0E-11 T 15-10-2018 IPR024490 Protein of unknown function DUF2759 C2I28_17075 1187111d62a1ea962b6c5c9d806d8e24 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 70 4.2E-7 T 15-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain C2I28_17075 1187111d62a1ea962b6c5c9d806d8e24 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 291 8.4E-25 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_17075 1187111d62a1ea962b6c5c9d806d8e24 302 SUPERFAMILY SSF161098 88 275 4.19E-29 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_17075 1187111d62a1ea962b6c5c9d806d8e24 302 Gene3D G3DSA:1.10.3720.10 81 291 1.5E-22 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_24165 c58f57d0dca75d30e15e7520e6dda14f 86 Pfam PF12652 CotJB protein 12 85 6.9E-30 T 15-10-2018 IPR024207 Spore coat assembly protein CotJB, domain C2I28_24165 c58f57d0dca75d30e15e7520e6dda14f 86 PIRSF PIRSF010606 1 86 6.3E-39 T 15-10-2018 IPR016571 Spore coat assembly protein CotJB C2I28_15495 9d3ec1574947e60f8e0c439c930a2f61 174 SUPERFAMILY SSF51182 4 166 2.88E-59 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_15495 9d3ec1574947e60f8e0c439c930a2f61 174 Gene3D G3DSA:2.60.120.10 1 167 1.3E-62 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_15495 9d3ec1574947e60f8e0c439c930a2f61 174 Pfam PF06172 Cupin superfamily (DUF985) 8 146 2.1E-47 T 15-10-2018 IPR009327 Cupin domain of unknown function DUF985 C2I28_05095 67acd5f625fbb17a956aa4e88f1c0fa7 332 Pfam PF01384 Phosphate transporter family 22 320 1.3E-89 T 15-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 C2I28_21980 7e3b1e79e0c78ff443a8c20eed980e85 151 Pfam PF00583 Acetyltransferase (GNAT) family 29 137 7.3E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_21980 7e3b1e79e0c78ff443a8c20eed980e85 151 Gene3D G3DSA:3.40.630.30 2 150 1.5E-17 T 15-10-2018 C2I28_21980 7e3b1e79e0c78ff443a8c20eed980e85 151 SUPERFAMILY SSF55729 4 142 2.09E-17 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22740 142d39229c8354869185a31db393705b 408 Pfam PF00909 Ammonium Transporter Family 7 403 6.3E-132 T 15-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 C2I28_22740 142d39229c8354869185a31db393705b 408 TIGRFAM TIGR00836 amt: ammonium transporter 5 403 1.7E-143 T 15-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 C2I28_22740 142d39229c8354869185a31db393705b 408 SUPERFAMILY SSF111352 3 383 4.58E-123 T 15-10-2018 C2I28_22740 142d39229c8354869185a31db393705b 408 PRINTS PR00342 Rhesus blood group protein signature 228 250 3.5E-5 T 15-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 C2I28_22740 142d39229c8354869185a31db393705b 408 PRINTS PR00342 Rhesus blood group protein signature 103 119 3.5E-5 T 15-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 C2I28_22740 142d39229c8354869185a31db393705b 408 PRINTS PR00342 Rhesus blood group protein signature 283 301 3.5E-5 T 15-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 C2I28_22740 142d39229c8354869185a31db393705b 408 PRINTS PR00342 Rhesus blood group protein signature 197 215 3.5E-5 T 15-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 C2I28_22740 142d39229c8354869185a31db393705b 408 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 15-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 C2I28_22740 142d39229c8354869185a31db393705b 408 Gene3D G3DSA:1.10.3430.10 1 408 5.2E-144 T 15-10-2018 IPR029020 Ammonium/urea transporter C2I28_09940 0cbaacb186f9f039835058d45defcabe 279 PIRSF PIRSF035875 4 279 4.5E-80 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_09940 0cbaacb186f9f039835058d45defcabe 279 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 12 270 5.3E-62 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_09940 0cbaacb186f9f039835058d45defcabe 279 Pfam PF03631 Virulence factor BrkB 22 273 2.9E-69 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_06820 9322392dcd6abd3de76488efb7d88ed4 251 Pfam PF00121 Triosephosphate isomerase 5 246 4.8E-94 T 15-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06820 9322392dcd6abd3de76488efb7d88ed4 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 241 1.8E-57 T 15-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06820 9322392dcd6abd3de76488efb7d88ed4 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 61.165 T 15-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06820 9322392dcd6abd3de76488efb7d88ed4 251 Gene3D G3DSA:3.20.20.70 2 251 1.5E-104 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_06820 9322392dcd6abd3de76488efb7d88ed4 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 15-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_06820 9322392dcd6abd3de76488efb7d88ed4 251 SUPERFAMILY SSF51351 1 248 6.81E-95 T 15-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 C2I28_09885 f814473f7e082de8b5262c384abf273a 361 Gene3D G3DSA:3.90.440.10 82 192 1.6E-155 T 15-10-2018 C2I28_09885 f814473f7e082de8b5262c384abf273a 361 SUPERFAMILY SSF56512 3 360 6.41E-170 T 15-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 C2I28_09885 f814473f7e082de8b5262c384abf273a 361 PIRSF PIRSF037219 1 361 2.1E-187 T 15-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 C2I28_09885 f814473f7e082de8b5262c384abf273a 361 Pfam PF02898 Nitric oxide synthase, oxygenase domain 3 360 8.0E-172 T 15-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 C2I28_09885 f814473f7e082de8b5262c384abf273a 361 Gene3D G3DSA:3.90.1230.10 193 299 1.6E-155 T 15-10-2018 C2I28_09885 f814473f7e082de8b5262c384abf273a 361 Gene3D G3DSA:3.90.340.10 4 354 1.6E-155 T 15-10-2018 C2I28_25535 7829d7edf08c888e3dad04875b51e9c3 166 Gene3D G3DSA:3.40.630.30 4 166 5.7E-37 T 15-10-2018 C2I28_25535 7829d7edf08c888e3dad04875b51e9c3 166 SUPERFAMILY SSF55729 7 149 1.13E-23 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_25535 7829d7edf08c888e3dad04875b51e9c3 166 Pfam PF00583 Acetyltransferase (GNAT) family 21 144 1.9E-15 T 15-10-2018 IPR000182 GNAT domain C2I28_19410 5ceb10a6d81403f71b88448146ce1501 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 271 287 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_19410 5ceb10a6d81403f71b88448146ce1501 399 Pfam PF07690 Major Facilitator Superfamily 19 232 2.0E-27 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_19410 5ceb10a6d81403f71b88448146ce1501 399 Gene3D G3DSA:1.20.1250.20 10 392 2.1E-52 T 15-10-2018 C2I28_19410 5ceb10a6d81403f71b88448146ce1501 399 Pfam PF00083 Sugar (and other) transporter 233 334 1.2E-6 T 15-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 C2I28_19410 5ceb10a6d81403f71b88448146ce1501 399 SUPERFAMILY SSF103473 12 394 3.4E-61 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_17225 f6c3cf71e17760e4c397de2f04a0a977 541 Gene3D G3DSA:3.30.300.310 434 537 9.0E-32 T 15-10-2018 C2I28_17225 f6c3cf71e17760e4c397de2f04a0a977 541 Pfam PF00501 AMP-binding enzyme 30 437 4.8E-103 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_17225 f6c3cf71e17760e4c397de2f04a0a977 541 Gene3D G3DSA:3.40.50.12780 13 433 2.8E-118 T 15-10-2018 C2I28_17225 f6c3cf71e17760e4c397de2f04a0a977 541 SUPERFAMILY SSF56801 21 532 5.89E-148 T 15-10-2018 C2I28_17225 f6c3cf71e17760e4c397de2f04a0a977 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 6.5E-21 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_17225 f6c3cf71e17760e4c397de2f04a0a977 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 15-10-2018 IPR020845 AMP-binding, conserved site C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 Pfam PF02779 Transketolase, pyrimidine binding domain 4 192 1.4E-56 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 SUPERFAMILY SSF52518 2 216 1.12E-67 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 Gene3D G3DSA:3.40.50.920 205 337 5.8E-47 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 Gene3D G3DSA:3.40.50.970 3 204 7.6E-84 T 15-10-2018 C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 SMART SM00861 5 192 1.5E-63 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 SUPERFAMILY SSF52922 201 336 9.03E-41 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_17360 2b7aa0b964ecfb17ddb11ace68ad66cc 344 Pfam PF02780 Transketolase, C-terminal domain 206 328 1.9E-41 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_10550 c21d85388e0d785b8bf97b3ea68a06eb 178 Gene3D G3DSA:2.30.30.40 106 173 1.3E-16 T 15-10-2018 C2I28_10550 c21d85388e0d785b8bf97b3ea68a06eb 178 SMART SM00287 44 107 2.3E-9 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_10550 c21d85388e0d785b8bf97b3ea68a06eb 178 SMART SM00287 108 175 1.6E-6 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_10550 c21d85388e0d785b8bf97b3ea68a06eb 178 Pfam PF08239 Bacterial SH3 domain 115 172 6.6E-11 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_10550 c21d85388e0d785b8bf97b3ea68a06eb 178 Pfam PF08239 Bacterial SH3 domain 53 103 1.3E-10 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_10550 c21d85388e0d785b8bf97b3ea68a06eb 178 Gene3D G3DSA:2.30.30.40 45 105 3.8E-13 T 15-10-2018 C2I28_15185 31b0aecc664a3df6bff6a4034250af7e 110 PIRSF PIRSF029938 1 110 5.3E-44 T 15-10-2018 IPR011229 Cell cycle protein GpsB C2I28_15185 31b0aecc664a3df6bff6a4034250af7e 110 Pfam PF05103 DivIVA protein 8 68 2.4E-17 T 15-10-2018 IPR007793 DivIVA family C2I28_15185 31b0aecc664a3df6bff6a4034250af7e 110 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 1.2E-15 T 15-10-2018 IPR019933 DivIVA domain C2I28_15185 31b0aecc664a3df6bff6a4034250af7e 110 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 106 24.267 T 15-10-2018 IPR011229 Cell cycle protein GpsB C2I28_21385 ca9c46c2f82afa9856b697af786492e8 382 Gene3D G3DSA:3.40.1710.10 43 146 1.2E-5 T 15-10-2018 C2I28_21385 ca9c46c2f82afa9856b697af786492e8 382 PRINTS PR00164 ABC-2 type transport system membrane protein signature 263 287 4.4E-7 T 15-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 C2I28_21385 ca9c46c2f82afa9856b697af786492e8 382 PRINTS PR00164 ABC-2 type transport system membrane protein signature 300 319 4.4E-7 T 15-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 C2I28_21385 ca9c46c2f82afa9856b697af786492e8 382 Pfam PF12698 ABC-2 family transporter protein 20 370 2.1E-47 T 15-10-2018 C2I28_18840 a119c785b9e2e6b43544c7de2205721f 216 Pfam PF13614 AAA domain 54 188 2.9E-12 T 15-10-2018 IPR025669 AAA domain C2I28_18840 a119c785b9e2e6b43544c7de2205721f 216 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 27 215 3.6E-48 T 15-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 C2I28_18840 a119c785b9e2e6b43544c7de2205721f 216 Gene3D G3DSA:3.40.50.300 2 216 7.0E-62 T 15-10-2018 C2I28_18840 a119c785b9e2e6b43544c7de2205721f 216 SUPERFAMILY SSF52540 45 214 1.66E-32 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_03965 404d3cd17344cf2b0eaee9905d80520e 277 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 2 277 68.433 T 15-10-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I28_03965 404d3cd17344cf2b0eaee9905d80520e 277 Pfam PF03099 Biotin/lipoate A/B protein ligase family 51 188 1.9E-28 T 15-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 C2I28_03965 404d3cd17344cf2b0eaee9905d80520e 277 SUPERFAMILY SSF55681 4 277 2.9E-74 T 15-10-2018 C2I28_03965 404d3cd17344cf2b0eaee9905d80520e 277 Gene3D G3DSA:3.30.930.10 3 277 5.4E-74 T 15-10-2018 C2I28_20800 bc04b70fa43ede8d04f45a31a244d5a4 479 PIRSF PIRSF006060 1 470 1.7E-88 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_20800 bc04b70fa43ede8d04f45a31a244d5a4 479 Gene3D G3DSA:1.20.1740.10 5 474 7.9E-63 T 15-10-2018 C2I28_20800 bc04b70fa43ede8d04f45a31a244d5a4 479 ProSitePatterns PS00218 Amino acid permeases signature. 40 71 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_20800 bc04b70fa43ede8d04f45a31a244d5a4 479 Pfam PF00324 Amino acid permease 15 464 1.2E-137 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_20100 47233f231838b7155046f369c4e22dbb 285 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 256 1.5E-73 T 15-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region C2I28_20100 47233f231838b7155046f369c4e22dbb 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 90 111 5.9E-37 T 15-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) C2I28_20100 47233f231838b7155046f369c4e22dbb 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 5.9E-37 T 15-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) C2I28_20100 47233f231838b7155046f369c4e22dbb 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 131 153 5.9E-37 T 15-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) C2I28_20100 47233f231838b7155046f369c4e22dbb 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 154 174 5.9E-37 T 15-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) C2I28_20100 47233f231838b7155046f369c4e22dbb 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 194 211 5.9E-37 T 15-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) C2I28_20100 47233f231838b7155046f369c4e22dbb 285 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 5.9E-37 T 15-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) C2I28_20100 47233f231838b7155046f369c4e22dbb 285 Gene3D G3DSA:2.120.10.30 1 284 7.6E-90 T 15-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I28_20100 47233f231838b7155046f369c4e22dbb 285 SUPERFAMILY SSF63829 9 282 1.9E-58 T 15-10-2018 C2I28_02750 a927926fec87ea571aab19dff3ba4e45 247 SMART SM00332 1 240 2.2E-15 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_02750 a927926fec87ea571aab19dff3ba4e45 247 SUPERFAMILY SSF81606 3 242 9.16E-62 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_02750 a927926fec87ea571aab19dff3ba4e45 247 Gene3D G3DSA:3.60.40.10 1 246 7.3E-71 T 15-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_02750 a927926fec87ea571aab19dff3ba4e45 247 SMART SM00331 7 242 9.0E-51 T 15-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 C2I28_02750 a927926fec87ea571aab19dff3ba4e45 247 Pfam PF13672 Protein phosphatase 2C 11 215 1.8E-21 T 15-10-2018 C2I28_11005 1763c58f6f089d135e04b752de284659 537 Gene3D G3DSA:3.30.300.310 430 536 6.4E-31 T 15-10-2018 C2I28_11005 1763c58f6f089d135e04b752de284659 537 SUPERFAMILY SSF56801 7 533 3.66E-132 T 15-10-2018 C2I28_11005 1763c58f6f089d135e04b752de284659 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 520 1.5E-17 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_11005 1763c58f6f089d135e04b752de284659 537 Gene3D G3DSA:3.40.50.12780 1 429 4.5E-116 T 15-10-2018 C2I28_11005 1763c58f6f089d135e04b752de284659 537 Pfam PF00501 AMP-binding enzyme 21 434 1.1E-94 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 153 174 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 436 455 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 2.8E-46 T 15-10-2018 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 800 0.0 T 15-10-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 Pfam PF13244 Domain of unknown function (DUF4040) 637 701 1.5E-20 T 15-10-2018 IPR025383 Domain of unknown function DUF4040 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 Pfam PF00361 Proton-conducting membrane transporter 129 423 2.4E-70 T 15-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 116 2.4E-10 T 15-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 3.5E-8 T 15-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 367 389 3.5E-8 T 15-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I28_06245 752f51033e91e0c7eee41b3c368cbe6d 801 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 259 281 3.5E-8 T 15-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 C2I28_25960 e1f3a15aeab8785857623c9e9db530f3 189 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 2.4E-23 T 15-10-2018 IPR000182 GNAT domain C2I28_25960 e1f3a15aeab8785857623c9e9db530f3 189 Gene3D G3DSA:3.40.630.30 3 173 3.3E-37 T 15-10-2018 C2I28_25960 e1f3a15aeab8785857623c9e9db530f3 189 SUPERFAMILY SSF55729 3 150 5.62E-34 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22310 5e0ae180032d5b5940a4042fc029fe05 183 Gene3D G3DSA:3.40.50.1240 1 181 1.7E-12 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_22310 5e0ae180032d5b5940a4042fc029fe05 183 SUPERFAMILY SSF53254 46 180 1.22E-12 T 15-10-2018 IPR029033 Histidine phosphatase superfamily C2I28_22310 5e0ae180032d5b5940a4042fc029fe05 183 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 45 176 7.4E-11 T 15-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 C2I28_14975 a80a9082bd70999420849c8a9f11f049 236 Gene3D G3DSA:3.40.50.10320 3 236 1.6E-85 T 15-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I28_14975 a80a9082bd70999420849c8a9f11f049 236 SUPERFAMILY SSF102588 6 229 2.35E-55 T 15-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 C2I28_14975 a80a9082bd70999420849c8a9f11f049 236 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 125 2.7E-24 T 15-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 C2I28_14975 a80a9082bd70999420849c8a9f11f049 236 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 227 7.9E-98 T 15-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 C2I28_13295 b46ab91c82a680aa3a899b01753d7f1f 236 Gene3D G3DSA:3.30.240.20 177 236 4.5E-22 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_13295 b46ab91c82a680aa3a899b01753d7f1f 236 Pfam PF04239 Protein of unknown function (DUF421) 96 211 3.4E-34 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_13295 b46ab91c82a680aa3a899b01753d7f1f 236 Pfam PF04239 Protein of unknown function (DUF421) 178 235 3.1E-9 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_13295 b46ab91c82a680aa3a899b01753d7f1f 236 Gene3D G3DSA:3.30.240.20 90 162 9.7E-24 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_02325 27c7ae6da87e7123a99dd1d80d141002 99 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 9 94 1.6E-18 T 15-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 C2I28_02325 27c7ae6da87e7123a99dd1d80d141002 99 Gene3D G3DSA:3.30.1330.30 1 99 2.8E-39 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_02325 27c7ae6da87e7123a99dd1d80d141002 99 SUPERFAMILY SSF55315 4 97 1.28E-27 T 15-10-2018 IPR029064 50S ribosomal protein L30e-like C2I28_19615 6658401a45cccfef1ef9edf8b24eed2d 168 Pfam PF13798 Protein of unknown function with PCYCGC motif 11 166 4.3E-62 T 15-10-2018 IPR025673 Protein of unknown function with PCYCGC motif C2I28_10960 95b47231c985723e04a383720005a8eb 300 Gene3D G3DSA:1.10.10.2840 180 298 2.8E-16 T 15-10-2018 C2I28_10960 95b47231c985723e04a383720005a8eb 300 SUPERFAMILY SSF46689 237 269 1.79E-5 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_10960 95b47231c985723e04a383720005a8eb 300 Pfam PF13556 PucR C-terminal helix-turn-helix domain 234 291 1.1E-16 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_26060 edbe8d530b4f3c7d68b931a5aca6c635 465 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 24 457 1.3E-148 T 15-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 C2I28_26060 edbe8d530b4f3c7d68b931a5aca6c635 465 Pfam PF13347 MFS/sugar transport protein 26 446 3.9E-101 T 15-10-2018 C2I28_26060 edbe8d530b4f3c7d68b931a5aca6c635 465 SUPERFAMILY SSF103473 25 444 2.75E-38 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_26060 edbe8d530b4f3c7d68b931a5aca6c635 465 Gene3D G3DSA:1.20.1250.20 32 441 3.1E-22 T 15-10-2018 C2I28_22675 eafec89eab53b4eb786051f7f70358f0 298 SUPERFAMILY SSF51735 1 289 1.1E-29 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_22675 eafec89eab53b4eb786051f7f70358f0 298 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 209 5.8E-7 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_22675 eafec89eab53b4eb786051f7f70358f0 298 Gene3D G3DSA:3.40.50.720 1 294 3.6E-29 T 15-10-2018 C2I28_27435 c7b21e38e92898861b39299efcfd7a9b 360 Pfam PF00534 Glycosyl transferases group 1 167 330 5.1E-21 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_27435 c7b21e38e92898861b39299efcfd7a9b 360 Gene3D G3DSA:3.40.50.2000 148 338 5.2E-30 T 15-10-2018 C2I28_27435 c7b21e38e92898861b39299efcfd7a9b 360 SUPERFAMILY SSF53756 5 354 2.15E-35 T 15-10-2018 C2I28_26905 0be774540d6e10fa8a953f792ac4695b 583 Pfam PF09491 AlwI restriction endonuclease 73 537 3.0E-90 T 15-10-2018 IPR018573 Restriction endonuclease, type II, AlwI C2I28_26905 0be774540d6e10fa8a953f792ac4695b 583 Gene3D G3DSA:3.40.91.50 365 583 3.8E-58 T 15-10-2018 C2I28_17465 868e45b10fb952b82a4981a7d035e8b8 454 Gene3D G3DSA:1.20.1250.20 10 209 2.1E-15 T 15-10-2018 C2I28_17465 868e45b10fb952b82a4981a7d035e8b8 454 Pfam PF13347 MFS/sugar transport protein 16 427 1.8E-103 T 15-10-2018 C2I28_17465 868e45b10fb952b82a4981a7d035e8b8 454 SUPERFAMILY SSF103473 12 425 2.62E-44 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_17465 868e45b10fb952b82a4981a7d035e8b8 454 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 65 90 - T 15-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 C2I28_17465 868e45b10fb952b82a4981a7d035e8b8 454 Gene3D G3DSA:1.20.1250.20 214 428 4.1E-15 T 15-10-2018 C2I28_17465 868e45b10fb952b82a4981a7d035e8b8 454 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 15 440 2.6E-130 T 15-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 C2I28_18695 892ab0db6e835826c7afa9d2e1f07dfd 160 Gene3D G3DSA:3.40.630.30 1 159 5.4E-38 T 15-10-2018 C2I28_18695 892ab0db6e835826c7afa9d2e1f07dfd 160 Pfam PF13302 Acetyltransferase (GNAT) domain 2 139 5.1E-29 T 15-10-2018 IPR000182 GNAT domain C2I28_18695 892ab0db6e835826c7afa9d2e1f07dfd 160 SUPERFAMILY SSF55729 2 144 8.86E-33 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 460 480 - T 15-10-2018 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 SUPERFAMILY SSF51905 1 490 6.29E-63 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 492 5.1E-149 T 15-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 Gene3D G3DSA:3.50.50.60 2 89 1.2E-25 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 Gene3D G3DSA:3.50.50.60 201 324 2.6E-17 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 Pfam PF01593 Flavin containing amine oxidoreductase 13 472 7.7E-21 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 PRINTS PR00419 Adrenodoxin reductase family signature 27 40 4.8E-8 T 15-10-2018 C2I28_11435 7d8e38d0053b842f9004489b25be697e 510 PRINTS PR00419 Adrenodoxin reductase family signature 4 26 4.8E-8 T 15-10-2018 C2I28_02520 defa30152f1e189177f4a647109b9623 262 Pfam PF02108 Flagellar assembly protein FliH 115 239 4.1E-8 T 15-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE C2I28_02520 defa30152f1e189177f4a647109b9623 262 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 1 254 9.4E-58 T 15-10-2018 IPR022524 Flagellar assembly FliH, Bacilli C2I28_22120 ecc911cd2312184d579284591e7891c8 108 SUPERFAMILY SSF101386 31 89 5.23E-7 T 15-10-2018 C2I28_22120 ecc911cd2312184d579284591e7891c8 108 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 31 82 9.2E-5 T 15-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 C2I28_16100 50c65bcef9f577229c71f9f1fb7049bb 222 Pfam PF01965 DJ-1/PfpI family 28 218 5.4E-18 T 15-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 C2I28_16100 50c65bcef9f577229c71f9f1fb7049bb 222 SUPERFAMILY SSF52317 5 220 5.77E-68 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_16100 50c65bcef9f577229c71f9f1fb7049bb 222 Gene3D G3DSA:3.40.50.880 2 222 1.8E-76 T 15-10-2018 IPR029062 Class I glutamine amidotransferase-like C2I28_22645 53273fc44ccfd0f05d843758f0314a7d 202 Gene3D G3DSA:1.10.357.10 4 192 1.0E-52 T 15-10-2018 C2I28_22645 53273fc44ccfd0f05d843758f0314a7d 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.7E-6 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_22645 53273fc44ccfd0f05d843758f0314a7d 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.7E-6 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_22645 53273fc44ccfd0f05d843758f0314a7d 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.4E-11 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_22645 53273fc44ccfd0f05d843758f0314a7d 202 Pfam PF14278 Transcriptional regulator C-terminal region 94 171 8.6E-22 T 15-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type C2I28_22645 53273fc44ccfd0f05d843758f0314a7d 202 SUPERFAMILY SSF46689 7 75 2.21E-17 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_24745 dfb956546d98e3a3cd03d054708cdad0 191 Pfam PF01810 LysE type translocator 12 189 1.1E-15 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_22575 d19f58b2d04538333fa31b1fa41b6ad7 257 SUPERFAMILY SSF53474 19 246 2.53E-32 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_22575 d19f58b2d04538333fa31b1fa41b6ad7 257 PIRSF PIRSF017388 4 248 1.4E-61 T 15-10-2018 IPR012354 Esterase/lipase GO:0052689 C2I28_22575 d19f58b2d04538333fa31b1fa41b6ad7 257 Pfam PF12146 Serine aminopeptidase, S33 22 225 1.5E-22 T 15-10-2018 IPR022742 Serine aminopeptidase, S33 C2I28_22575 d19f58b2d04538333fa31b1fa41b6ad7 257 Gene3D G3DSA:3.40.50.1820 1 246 3.5E-54 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 SUPERFAMILY SSF53137 14 129 1.24E-49 T 15-10-2018 C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 2.2E-58 T 15-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 Gene3D G3DSA:3.30.420.80 1 129 8.1E-54 T 15-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.434 T 15-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 PIRSF PIRSF002131 1 129 9.9E-54 T 15-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 15-10-2018 IPR018102 Ribosomal S11, conserved site C2I28_08815 e47a34824e9257eefd2502ee99f052e1 129 Pfam PF00411 Ribosomal protein S11 19 128 1.9E-52 T 15-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 C2I28_02540 0f1181a0925ea37767db7b26f441426e 149 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 149 5.0E-50 T 15-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 C2I28_02540 0f1181a0925ea37767db7b26f441426e 149 Pfam PF00460 Flagella basal body rod protein 7 34 1.5E-6 T 15-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I28_02540 0f1181a0925ea37767db7b26f441426e 149 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 15-10-2018 IPR019776 Flagellar basal body rod protein, conserved site C2I28_02540 0f1181a0925ea37767db7b26f441426e 149 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 98 146 1.4E-13 T 15-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain C2I28_03120 43404920e6e09079c15ac0448036b530 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 71 159 6.6E-10 T 15-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 C2I28_03120 43404920e6e09079c15ac0448036b530 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 4.8E-13 T 15-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_03120 43404920e6e09079c15ac0448036b530 255 SUPERFAMILY SSF81648 21 158 9.42E-31 T 15-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 C2I28_03120 43404920e6e09079c15ac0448036b530 255 PIRSF PIRSF036636 1 255 1.9E-143 T 15-10-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 C2I28_03120 43404920e6e09079c15ac0448036b530 255 Gene3D G3DSA:1.10.760.10 182 251 5.5E-15 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_03120 43404920e6e09079c15ac0448036b530 255 SUPERFAMILY SSF46626 137 252 2.04E-13 T 15-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 C2I28_03120 43404920e6e09079c15ac0448036b530 255 Gene3D G3DSA:1.20.810.10 13 169 8.0E-26 T 15-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 C2I28_25055 bdbaca57290211cac698bcfa4236d524 467 Pfam PF02614 Glucuronate isomerase 1 464 1.4E-214 T 15-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 C2I28_25055 bdbaca57290211cac698bcfa4236d524 467 Hamap MF_00675 Uronate isomerase [uxaC]. 2 466 47.422 T 15-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 C2I28_25055 bdbaca57290211cac698bcfa4236d524 467 Gene3D G3DSA:1.10.2020.10 46 136 7.8E-198 T 15-10-2018 C2I28_25055 bdbaca57290211cac698bcfa4236d524 467 SUPERFAMILY SSF51556 2 464 6.58E-174 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_25055 bdbaca57290211cac698bcfa4236d524 467 Gene3D G3DSA:3.20.20.140 7 464 7.8E-198 T 15-10-2018 C2I28_03460 6800cea0d15c8240c7369c48d8be9c6e 173 SUPERFAMILY SSF140663 2 125 6.15E-33 T 15-10-2018 IPR023203 TTHA0068-like superfamily C2I28_03460 6800cea0d15c8240c7369c48d8be9c6e 173 Pfam PF03745 Domain of unknown function (DUF309) 7 65 6.2E-21 T 15-10-2018 IPR005500 Protein of unknown function DUF309 C2I28_03460 6800cea0d15c8240c7369c48d8be9c6e 173 Gene3D G3DSA:1.20.58.500 5 101 1.2E-15 T 15-10-2018 C2I28_01950 8d0af95fc1b39717d8d760a26d46cfd0 141 ProDom PD086666 YNEK BH2332 11 141 3.0E-44 T 15-10-2018 IPR020203 Uncharacterised protein family, YneK C2I28_01950 8d0af95fc1b39717d8d760a26d46cfd0 141 Pfam PF11084 Protein of unknown function (DUF2621) 3 141 8.0E-73 T 15-10-2018 IPR020203 Uncharacterised protein family, YneK C2I28_11775 d3c0c4af2f41caf83ce8b6842011d1d7 393 Pfam PF06054 Competence protein CoiA-like family 17 272 7.9E-55 T 15-10-2018 IPR010330 Competence-induced protein CoiA-like C2I28_26020 4be860b60e5b697ee5b238d0192e4714 106 SUPERFAMILY SSF46785 5 100 3.6E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_26020 4be860b60e5b697ee5b238d0192e4714 106 Pfam PF03551 Transcriptional regulator PadR-like family 16 87 3.3E-23 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_26020 4be860b60e5b697ee5b238d0192e4714 106 Gene3D G3DSA:1.10.10.10 1 106 6.8E-39 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_06035 16c005cede852f6186aabc200419b673 341 Pfam PF00483 Nucleotidyl transferase 16 148 6.3E-10 T 15-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 C2I28_06035 16c005cede852f6186aabc200419b673 341 Gene3D G3DSA:3.90.550.10 1 151 4.6E-23 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06035 16c005cede852f6186aabc200419b673 341 Gene3D G3DSA:3.90.550.10 152 235 5.3E-9 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06035 16c005cede852f6186aabc200419b673 341 SUPERFAMILY SSF53448 16 283 3.0E-37 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06035 16c005cede852f6186aabc200419b673 341 SUPERFAMILY SSF51161 251 323 1.91E-13 T 15-10-2018 IPR011004 Trimeric LpxA-like superfamily C2I28_06035 16c005cede852f6186aabc200419b673 341 Gene3D G3DSA:2.160.10.10 236 334 5.8E-26 T 15-10-2018 C2I28_17480 b55b297859b1a4473f7ade96c2d27764 65 Pfam PF08858 IDEAL domain 25 61 1.1E-13 T 15-10-2018 IPR014957 IDEAL domain C2I28_17480 b55b297859b1a4473f7ade96c2d27764 65 SMART SM00914 25 61 4.3E-9 T 15-10-2018 IPR014957 IDEAL domain C2I28_17480 b55b297859b1a4473f7ade96c2d27764 65 Gene3D G3DSA:4.10.810.10 11 65 1.2E-18 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_13045 22c3d51e996351cbc5d80cc3ed52e6f5 442 Gene3D G3DSA:3.20.20.140 68 376 7.4E-114 T 15-10-2018 C2I28_13045 22c3d51e996351cbc5d80cc3ed52e6f5 442 Gene3D G3DSA:2.30.40.10 15 415 7.4E-114 T 15-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 C2I28_13045 22c3d51e996351cbc5d80cc3ed52e6f5 442 Pfam PF01979 Amidohydrolase family 63 405 1.1E-22 T 15-10-2018 IPR006680 Amidohydrolase-related GO:0016787 C2I28_13045 22c3d51e996351cbc5d80cc3ed52e6f5 442 SUPERFAMILY SSF51556 67 387 1.09E-72 T 15-10-2018 IPR032466 Metal-dependent hydrolase C2I28_04310 5fe7c42efeeda43dba073b588eb17116 156 SUPERFAMILY SSF55486 2 155 1.44E-46 T 15-10-2018 C2I28_04310 5fe7c42efeeda43dba073b588eb17116 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 153 1.0E-43 T 15-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 C2I28_04310 5fe7c42efeeda43dba073b588eb17116 156 Gene3D G3DSA:3.40.390.30 2 156 5.2E-48 T 15-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 C2I28_04310 5fe7c42efeeda43dba073b588eb17116 156 Pfam PF02130 Uncharacterized protein family UPF0054 14 152 6.8E-48 T 15-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 C2I28_04310 5fe7c42efeeda43dba073b588eb17116 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 24.371 T 15-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 C2I28_04310 5fe7c42efeeda43dba073b588eb17116 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 15-10-2018 IPR020549 Endoribonuclease YbeY, conserved site C2I28_13215 d31aba34353ae981f4e760394fcd82f2 381 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 379 37.72 T 15-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 C2I28_13215 d31aba34353ae981f4e760394fcd82f2 381 Gene3D G3DSA:3.30.420.40 149 339 4.5E-128 T 15-10-2018 C2I28_13215 d31aba34353ae981f4e760394fcd82f2 381 SUPERFAMILY SSF53067 1 329 1.94E-20 T 15-10-2018 C2I28_13215 d31aba34353ae981f4e760394fcd82f2 381 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 379 9.5E-105 T 15-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 C2I28_13215 d31aba34353ae981f4e760394fcd82f2 381 Gene3D G3DSA:3.30.420.40 8 374 4.5E-128 T 15-10-2018 C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Pfam PF03413 Peptidase propeptide and YPEB domain 43 98 3.8E-5 T 15-10-2018 IPR025711 PepSY domain C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Pfam PF03413 Peptidase propeptide and YPEB domain 228 280 6.8E-6 T 15-10-2018 IPR025711 PepSY domain C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Pfam PF03413 Peptidase propeptide and YPEB domain 292 342 4.9E-4 T 15-10-2018 IPR025711 PepSY domain C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Gene3D G3DSA:3.10.450.40 161 222 2.2E-5 T 15-10-2018 C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Gene3D G3DSA:3.10.450.40 32 100 1.7E-6 T 15-10-2018 C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Gene3D G3DSA:3.10.450.40 223 286 5.2E-11 T 15-10-2018 C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Gene3D G3DSA:3.10.450.40 101 160 7.3E-6 T 15-10-2018 C2I28_07800 b1fa25dc1c109f8cedbd022829b70cf0 345 Gene3D G3DSA:3.10.450.40 287 345 1.6E-7 T 15-10-2018 C2I28_27660 d1b4c543b103d5bd8fccea01277ff94d 219 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 12 171 7.4E-30 T 15-10-2018 IPR014903 Protein of unknown function DUF1796 C2I28_12250 a4f2837ecaee8bb5a125e67b58d602ce 335 Gene3D G3DSA:2.102.10.10 7 134 2.1E-36 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_12250 a4f2837ecaee8bb5a125e67b58d602ce 335 Pfam PF00355 Rieske [2Fe-2S] domain 11 90 1.9E-19 T 15-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I28_12250 a4f2837ecaee8bb5a125e67b58d602ce 335 SUPERFAMILY SSF55961 119 320 1.15E-23 T 15-10-2018 C2I28_12250 a4f2837ecaee8bb5a125e67b58d602ce 335 Gene3D G3DSA:3.30.530.90 135 320 1.1E-11 T 15-10-2018 C2I28_12250 a4f2837ecaee8bb5a125e67b58d602ce 335 SUPERFAMILY SSF50022 5 120 3.14E-33 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_13455 a4589ad5ba969bdd38324731c2b28867 55 Pfam PF13076 Fur-regulated basic protein A 12 46 7.1E-14 T 15-10-2018 IPR025072 Fur-regulated basic protein A C2I28_08110 da282926754b9f6654affe705d814ab5 211 PIRSF PIRSF000705 1 210 1.1E-57 T 15-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 C2I28_08110 da282926754b9f6654affe705d814ab5 211 Gene3D G3DSA:3.40.50.300 5 208 2.6E-47 T 15-10-2018 C2I28_08110 da282926754b9f6654affe705d814ab5 211 Pfam PF01712 Deoxynucleoside kinase 7 204 8.4E-49 T 15-10-2018 IPR031314 Deoxynucleoside kinase domain C2I28_08110 da282926754b9f6654affe705d814ab5 211 SUPERFAMILY SSF52540 1 204 4.53E-47 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_00405 53ad2006a4f1fdeb8f5a3824f6b15d0e 452 Pfam PF07690 Major Facilitator Superfamily 30 410 2.8E-23 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_00405 53ad2006a4f1fdeb8f5a3824f6b15d0e 452 Gene3D G3DSA:1.20.1250.20 23 449 7.4E-34 T 15-10-2018 C2I28_00405 53ad2006a4f1fdeb8f5a3824f6b15d0e 452 SUPERFAMILY SSF103473 25 447 3.27E-38 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21575 9fe71372f180b297ecfa11c587d6b538 538 Pfam PF14266 Putative component of 'biosynthetic module' 40 528 7.5E-147 T 15-10-2018 IPR025647 Putative component of 'biosynthetic module' C2I28_11750 a4cbe453adc5ff8b06f4a95b2569675d 137 Pfam PF03817 Malonate transporter MadL subunit 1 117 2.2E-47 T 15-10-2018 IPR004690 Malonate transporter MadL subunit GO:0016020 C2I28_11750 a4cbe453adc5ff8b06f4a95b2569675d 137 TIGRFAM TIGR00807 malonate_madL: malonate transporter, MadL subunit 1 121 5.2E-46 T 15-10-2018 IPR004690 Malonate transporter MadL subunit GO:0016020 C2I28_14925 39ec9d6406065fba1fee0de4d5482eb5 312 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 282 1.9E-64 T 15-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related C2I28_14925 39ec9d6406065fba1fee0de4d5482eb5 312 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 4 284 1.5E-127 T 15-10-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 Gene3D G3DSA:3.40.50.150 84 284 3.8E-56 T 15-10-2018 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 SUPERFAMILY SSF53335 85 264 1.01E-40 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 SUPERFAMILY SSF47757 17 84 2.09E-7 T 15-10-2018 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 Pfam PF03705 CheR methyltransferase, all-alpha domain 21 66 7.8E-10 T 15-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 Pfam PF01739 CheR methyltransferase, SAM binding domain 85 265 9.9E-41 T 15-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 SMART SM00138 19 282 3.6E-35 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 PRINTS PR00996 Glutamate methyltransferase family signature 114 134 7.5E-25 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 7.5E-25 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 PRINTS PR00996 Glutamate methyltransferase family signature 78 90 7.5E-25 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 PRINTS PR00996 Glutamate methyltransferase family signature 146 162 7.5E-25 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_15735 f5a698dfaa0b38f221091086ecd5bc4b 284 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 7.5E-25 T 15-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 C2I28_23165 2520e3773317c6187d6a5be7e0be8e68 416 Pfam PF00266 Aminotransferase class-V 38 359 7.2E-35 T 15-10-2018 IPR000192 Aminotransferase class V domain C2I28_23165 2520e3773317c6187d6a5be7e0be8e68 416 PIRSF PIRSF000524 5 413 2.4E-138 T 15-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 C2I28_23165 2520e3773317c6187d6a5be7e0be8e68 416 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 209 - T 15-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site C2I28_23165 2520e3773317c6187d6a5be7e0be8e68 416 Gene3D G3DSA:3.90.1150.10 9 384 1.3E-145 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_23165 2520e3773317c6187d6a5be7e0be8e68 416 SUPERFAMILY SSF53383 10 387 1.63E-96 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_23165 2520e3773317c6187d6a5be7e0be8e68 416 Gene3D G3DSA:3.40.640.10 23 286 1.3E-145 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 Gene3D G3DSA:3.30.70.260 119 191 2.1E-85 T 15-10-2018 C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 214 1.1E-67 T 15-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 Gene3D G3DSA:3.40.50.1360 4 210 2.1E-85 T 15-10-2018 C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 220 32.646 T 15-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 215 5.6E-87 T 15-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 SUPERFAMILY SSF100950 3 174 2.58E-46 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_13250 8c26b36db92164a0b54949ae905e8dd6 222 SUPERFAMILY SSF75445 125 203 1.1E-24 T 15-10-2018 C2I28_14095 28707770364c90c1648de97219caf108 148 Pfam PF13673 Acetyltransferase (GNAT) domain 38 147 5.3E-15 T 15-10-2018 IPR000182 GNAT domain C2I28_14095 28707770364c90c1648de97219caf108 148 SUPERFAMILY SSF55729 15 139 5.56E-18 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_14095 28707770364c90c1648de97219caf108 148 Gene3D G3DSA:3.40.630.30 6 146 1.9E-19 T 15-10-2018 C2I28_03490 a2ce1e0dfd099cf8b64517297ee71e92 188 Pfam PF14097 Stage V sporulation protein AE1 5 184 1.1E-78 T 15-10-2018 IPR025914 Stage V sporulation protein AE C2I28_03575 848fb58048d693ddbb41f41b0b81d70a 55 Pfam PF13072 Protein of unknown function (DUF3936) 1 36 6.4E-22 T 15-10-2018 IPR025177 Cell division inhibitor MciZ C2I28_20165 3ced05ad88c281a21d4cd57807c36476 299 SUPERFAMILY SSF103481 188 284 7.06E-11 T 15-10-2018 C2I28_20165 3ced05ad88c281a21d4cd57807c36476 299 SUPERFAMILY SSF103481 41 141 3.53E-18 T 15-10-2018 C2I28_20165 3ced05ad88c281a21d4cd57807c36476 299 Pfam PF00892 EamA-like transporter family 150 282 2.6E-21 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_20165 3ced05ad88c281a21d4cd57807c36476 299 Pfam PF00892 EamA-like transporter family 8 138 4.1E-26 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_14320 95bd2d7d2c623e2869588a1d0916dae1 358 Gene3D G3DSA:3.40.50.2300 62 327 8.4E-81 T 15-10-2018 C2I28_14320 95bd2d7d2c623e2869588a1d0916dae1 358 Pfam PF13407 Periplasmic binding protein domain 62 320 5.0E-37 T 15-10-2018 IPR025997 Periplasmic binding protein C2I28_14320 95bd2d7d2c623e2869588a1d0916dae1 358 SUPERFAMILY SSF53822 58 336 8.88E-52 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_14320 95bd2d7d2c623e2869588a1d0916dae1 358 Gene3D G3DSA:3.40.50.2300 161 333 8.4E-81 T 15-10-2018 C2I28_27330 1bd693c3188beb684f33ceb1832d671b 233 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 18 185 1.0E-18 T 15-10-2018 IPR014903 Protein of unknown function DUF1796 C2I28_05660 f898fe2cf4f1cf95ab4c739058f2a7c7 161 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 94 3.1E-23 T 15-10-2018 IPR009293 Uncharacterised protein family UPF0478 C2I28_05660 f898fe2cf4f1cf95ab4c739058f2a7c7 161 SUPERFAMILY SSF58104 23 133 4.05E-5 T 15-10-2018 C2I28_05660 f898fe2cf4f1cf95ab4c739058f2a7c7 161 Gene3D G3DSA:1.10.287.950 12 137 1.9E-5 T 15-10-2018 C2I28_00860 cd827624d4d7bb9a3a7e2f03b1e3a8e1 245 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00860 cd827624d4d7bb9a3a7e2f03b1e3a8e1 245 SUPERFAMILY SSF46955 4 113 2.16E-23 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_00860 cd827624d4d7bb9a3a7e2f03b1e3a8e1 245 Gene3D G3DSA:1.10.1660.10 3 132 3.7E-27 T 15-10-2018 C2I28_00860 cd827624d4d7bb9a3a7e2f03b1e3a8e1 245 SMART SM00422 4 73 1.2E-17 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_00860 cd827624d4d7bb9a3a7e2f03b1e3a8e1 245 Pfam PF13411 MerR HTH family regulatory protein 4 71 5.1E-15 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_19940 b37a44ae0705767ec5f2bd5965480632 159 Gene3D G3DSA:3.40.630.30 14 159 4.6E-21 T 15-10-2018 C2I28_19940 b37a44ae0705767ec5f2bd5965480632 159 Pfam PF00583 Acetyltransferase (GNAT) family 57 135 5.9E-11 T 15-10-2018 IPR000182 GNAT domain C2I28_19940 b37a44ae0705767ec5f2bd5965480632 159 SUPERFAMILY SSF55729 23 158 1.1E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18585 01b3d98c5ab3830d507dd8d48c197bf6 202 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 13 199 32.714 T 15-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I28_18585 01b3d98c5ab3830d507dd8d48c197bf6 202 SUPERFAMILY SSF50486 9 201 1.18E-63 T 15-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 C2I28_18585 01b3d98c5ab3830d507dd8d48c197bf6 202 Gene3D G3DSA:3.10.300.10 7 202 2.0E-64 T 15-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I28_18585 01b3d98c5ab3830d507dd8d48c197bf6 202 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 14 196 1.2E-58 T 15-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I28_18585 01b3d98c5ab3830d507dd8d48c197bf6 202 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 11 199 2.0E-69 T 15-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 C2I28_01030 bdd463bbd7808cee5a73b7fad82db59f 287 Gene3D G3DSA:3.30.565.40 75 188 8.9E-27 T 15-10-2018 C2I28_01030 bdd463bbd7808cee5a73b7fad82db59f 287 Pfam PF11738 Protein of unknown function (DUF3298) 193 273 2.5E-18 T 15-10-2018 IPR021729 Domain of unknown function DUF3298 C2I28_01030 bdd463bbd7808cee5a73b7fad82db59f 287 Gene3D G3DSA:3.90.640.20 189 287 6.6E-39 T 15-10-2018 IPR037126 PdaC/RsiV-like superfamily C2I28_18420 44f7b7a3802582627db42322416fcbff 354 Gene3D G3DSA:3.40.190.10 139 349 1.4E-133 T 15-10-2018 C2I28_18420 44f7b7a3802582627db42322416fcbff 354 Gene3D G3DSA:3.40.190.10 51 320 1.4E-133 T 15-10-2018 C2I28_18420 44f7b7a3802582627db42322416fcbff 354 SUPERFAMILY SSF53850 45 352 2.05E-85 T 15-10-2018 C2I28_18420 44f7b7a3802582627db42322416fcbff 354 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 72 84 - T 15-10-2018 IPR000957 Sulphate/thiosulphate-binding, conserved site C2I28_18420 44f7b7a3802582627db42322416fcbff 354 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 170 178 - T 15-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 C2I28_18420 44f7b7a3802582627db42322416fcbff 354 Pfam PF13531 Bacterial extracellular solute-binding protein 57 305 1.0E-42 T 15-10-2018 C2I28_18420 44f7b7a3802582627db42322416fcbff 354 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 44 350 4.5E-146 T 15-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 C2I28_13030 501e8d06212f344849364bb5f267ab8f 217 Pfam PF09347 Domain of unknown function (DUF1989) 20 184 1.2E-58 T 15-10-2018 IPR018959 Protein of unknown function DUF1989 C2I28_13030 501e8d06212f344849364bb5f267ab8f 217 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 15 214 9.1E-94 T 15-10-2018 IPR017791 Urea carboxylase-associated protein 1 C2I28_12395 7e80c8881dc72b95186c513384cf799e 72 Gene3D G3DSA:1.10.260.40 2 67 1.8E-22 T 15-10-2018 C2I28_12395 7e80c8881dc72b95186c513384cf799e 72 SUPERFAMILY SSF47413 3 67 1.13E-15 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_12395 7e80c8881dc72b95186c513384cf799e 72 Pfam PF01381 Helix-turn-helix 7 60 6.6E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_12395 7e80c8881dc72b95186c513384cf799e 72 SMART SM00530 6 61 4.9E-11 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_03200 771e6ab979eada65b58e16690907491a 390 Gene3D G3DSA:3.60.150.10 1 389 1.7E-158 T 15-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 15-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 37.154 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 15-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 PIRSF PIRSF001456 1 385 2.0E-136 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 Pfam PF01264 Chorismate synthase 1 364 1.8E-128 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 370 6.2E-135 T 15-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 SUPERFAMILY SSF103263 1 388 2.62E-153 T 15-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_03200 771e6ab979eada65b58e16690907491a 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 15-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 C2I28_25685 1628fe2cf0fd42c7c1a7674d2fab5d40 216 Pfam PF06161 Protein of unknown function (DUF975) 1 128 7.1E-12 T 15-10-2018 IPR010380 Protein of unknown function DUF975 C2I28_25685 1628fe2cf0fd42c7c1a7674d2fab5d40 216 Pfam PF06161 Protein of unknown function (DUF975) 121 210 4.6E-30 T 15-10-2018 IPR010380 Protein of unknown function DUF975 C2I28_10990 69e24fed1c48a5a174ee162f71bba33d 116 Gene3D G3DSA:1.20.1500.10 2 113 2.1E-36 T 15-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I28_10990 69e24fed1c48a5a174ee162f71bba33d 116 SUPERFAMILY SSF158622 3 113 1.57E-36 T 15-10-2018 IPR023378 YheA/YmcA-like domain superfamily C2I28_10990 69e24fed1c48a5a174ee162f71bba33d 116 Hamap MF_01526 UPF0342 protein . 2 113 18.966 T 15-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I28_10990 69e24fed1c48a5a174ee162f71bba33d 116 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 7 108 8.6E-24 T 15-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA C2I28_20715 52a4132e308d300952e127d1fd0fd293 166 SUPERFAMILY SSF55729 1 165 4.39E-31 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_20715 52a4132e308d300952e127d1fd0fd293 166 Gene3D G3DSA:3.40.630.30 1 166 5.1E-40 T 15-10-2018 C2I28_20715 52a4132e308d300952e127d1fd0fd293 166 Pfam PF00583 Acetyltransferase (GNAT) family 39 139 8.4E-18 T 15-10-2018 IPR000182 GNAT domain C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 SMART SM00155 142 169 2.2E-4 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 SMART SM00155 312 339 2.3E-4 T 15-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 Pfam PF13091 PLD-like domain 60 202 2.0E-13 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 Pfam PF13091 PLD-like domain 239 366 2.5E-27 T 15-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 SUPERFAMILY SSF56024 43 217 2.45E-40 T 15-10-2018 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 PIRSF PIRSF000850 297 391 0.004 T 15-10-2018 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 PIRSF PIRSF000850 224 301 4.7E-6 T 15-10-2018 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 PIRSF PIRSF000850 30 203 6.4 T 15-10-2018 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 Gene3D G3DSA:3.30.870.10 226 375 2.9E-28 T 15-10-2018 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 Gene3D G3DSA:3.30.870.10 36 225 6.3E-41 T 15-10-2018 C2I28_20185 15dfabef0812929629f2fc266806aaf8 399 SUPERFAMILY SSF56024 195 384 6.5E-36 T 15-10-2018 C2I28_05325 6b31d68be736870f4613f6185897174d 286 Pfam PF08812 YtxC-like family 56 269 1.1E-45 T 15-10-2018 IPR014199 Sporulation protein YtxC C2I28_13110 85dcd213a0a3b71b8cae7522b612a4ee 104 Pfam PF00893 Small Multidrug Resistance protein 1 92 3.1E-26 T 15-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 C2I28_13110 85dcd213a0a3b71b8cae7522b612a4ee 104 SUPERFAMILY SSF103481 6 102 2.35E-20 T 15-10-2018 C2I28_13110 85dcd213a0a3b71b8cae7522b612a4ee 104 Gene3D G3DSA:1.10.3730.20 1 104 4.0E-33 T 15-10-2018 C2I28_13615 c6ad166ce25dc8e65e20aac0bb448e15 263 SUPERFAMILY SSF89550 3 258 1.31E-46 T 15-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I28_13615 c6ad166ce25dc8e65e20aac0bb448e15 263 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 5 239 6.7E-42 T 15-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 C2I28_13615 c6ad166ce25dc8e65e20aac0bb448e15 263 Pfam PF02811 PHP domain 5 192 2.8E-13 T 15-10-2018 IPR004013 PHP domain GO:0003824 C2I28_13615 c6ad166ce25dc8e65e20aac0bb448e15 263 Gene3D G3DSA:3.20.20.140 2 259 3.3E-67 T 15-10-2018 C2I28_13995 379139f85e25b4a6e4f000e44637743e 407 Gene3D G3DSA:3.40.1710.10 44 130 9.0E-6 T 15-10-2018 C2I28_13995 379139f85e25b4a6e4f000e44637743e 407 Pfam PF12698 ABC-2 family transporter protein 20 349 4.9E-28 T 15-10-2018 C2I28_12770 998eb87e58771eefed4d870195be5bf3 212 Gene3D G3DSA:2.40.50.100 48 91 5.2E-5 T 15-10-2018 C2I28_12770 998eb87e58771eefed4d870195be5bf3 212 Gene3D G3DSA:2.40.30.170 98 212 2.6E-28 T 15-10-2018 C2I28_12770 998eb87e58771eefed4d870195be5bf3 212 SUPERFAMILY SSF51230 40 112 1.44E-12 T 15-10-2018 IPR011053 Single hybrid motif C2I28_12770 998eb87e58771eefed4d870195be5bf3 212 Pfam PF13437 HlyD family secretion protein 85 200 3.4E-13 T 15-10-2018 C2I28_15590 d10e0108d7d62533718a2b9773631fd9 267 SUPERFAMILY SSF54060 120 256 3.06E-38 T 15-10-2018 C2I28_15590 d10e0108d7d62533718a2b9773631fd9 267 Pfam PF04231 Endonuclease I 64 256 2.2E-32 T 15-10-2018 IPR007346 Endonuclease I GO:0004518 C2I28_07170 7cd9819b7f031d4a09fc03bdea1a69dc 145 Pfam PF03885 Protein of unknown function (DUF327) 18 144 5.2E-39 T 15-10-2018 IPR005585 Protein of unknown function DUF327 C2I28_07170 7cd9819b7f031d4a09fc03bdea1a69dc 145 SUPERFAMILY SSF158397 26 145 2.09E-34 T 15-10-2018 IPR024042 TM1646-like domain superfamily C2I28_07170 7cd9819b7f031d4a09fc03bdea1a69dc 145 Gene3D G3DSA:1.20.120.490 24 145 1.1E-38 T 15-10-2018 IPR024042 TM1646-like domain superfamily C2I28_24845 a2a6aa13bd23b7a8112a90a9d09fa8c0 179 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 4.5E-30 T 15-10-2018 IPR000182 GNAT domain C2I28_24845 a2a6aa13bd23b7a8112a90a9d09fa8c0 179 Gene3D G3DSA:3.40.630.30 3 171 1.7E-46 T 15-10-2018 C2I28_24845 a2a6aa13bd23b7a8112a90a9d09fa8c0 179 SUPERFAMILY SSF55729 1 174 2.75E-48 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_08535 49091f57042f7f02a37da8d7c8541dc8 357 SUPERFAMILY SSF55931 6 269 4.21E-89 T 15-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 C2I28_08535 49091f57042f7f02a37da8d7c8541dc8 357 Gene3D G3DSA:3.30.590.10 10 264 5.3E-77 T 15-10-2018 C2I28_08535 49091f57042f7f02a37da8d7c8541dc8 357 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 39.669 T 15-10-2018 IPR023660 Protein arginine kinase GO:0016775 C2I28_08535 49091f57042f7f02a37da8d7c8541dc8 357 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 53 254 1.2E-76 T 15-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 C2I28_08535 49091f57042f7f02a37da8d7c8541dc8 357 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 15-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 C2I28_03590 be615e69afe3037c8266f245cb3c9113 222 SMART SM00882 10 206 4.8E-77 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_03590 be615e69afe3037c8266f245cb3c9113 222 SUPERFAMILY SSF100950 7 218 2.39E-73 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_03590 be615e69afe3037c8266f245cb3c9113 222 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 8 212 1.1E-97 T 15-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 C2I28_03590 be615e69afe3037c8266f245cb3c9113 222 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 48 56 - T 15-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 C2I28_03590 be615e69afe3037c8266f245cb3c9113 222 Gene3D G3DSA:3.40.1080.10 5 218 6.1E-102 T 15-10-2018 C2I28_03590 be615e69afe3037c8266f245cb3c9113 222 Pfam PF01144 Coenzyme A transferase 10 205 1.5E-44 T 15-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 C2I28_01145 63a6b661266c47ac18795478667608ca 172 Gene3D G3DSA:3.10.129.10 1 166 3.9E-47 T 15-10-2018 C2I28_01145 63a6b661266c47ac18795478667608ca 172 Pfam PF03061 Thioesterase superfamily 28 99 2.3E-10 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_01145 63a6b661266c47ac18795478667608ca 172 SUPERFAMILY SSF54637 11 151 1.83E-36 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_08755 285af7bf685b5b1ed95fc9dde281fa5d 132 Pfam PF00410 Ribosomal protein S8 5 132 1.1E-54 T 15-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08755 285af7bf685b5b1ed95fc9dde281fa5d 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 15-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08755 285af7bf685b5b1ed95fc9dde281fa5d 132 Gene3D G3DSA:3.30.1370.30 4 74 5.8E-33 T 15-10-2018 C2I28_08755 285af7bf685b5b1ed95fc9dde281fa5d 132 Gene3D G3DSA:3.30.1490.10 75 132 2.1E-27 T 15-10-2018 C2I28_08755 285af7bf685b5b1ed95fc9dde281fa5d 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.015 T 15-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08755 285af7bf685b5b1ed95fc9dde281fa5d 132 SUPERFAMILY SSF56047 2 132 8.9E-50 T 15-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_01575 64e52f5d42998b70b23a6c578a04abe8 200 Pfam PF13021 Domain of unknown function (DUF3885) 159 192 4.4E-12 T 15-10-2018 IPR024976 Domain of unknown function DUF3885 C2I28_22020 dc655bdb146ff6452a01c463c781bfaf 394 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 377 1.5E-113 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_22020 dc655bdb146ff6452a01c463c781bfaf 394 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_22020 dc655bdb146ff6452a01c463c781bfaf 394 SUPERFAMILY SSF56796 9 388 1.31E-112 T 15-10-2018 C2I28_22020 dc655bdb146ff6452a01c463c781bfaf 394 Gene3D G3DSA:3.40.50.1970 3 185 1.3E-47 T 15-10-2018 C2I28_22020 dc655bdb146ff6452a01c463c781bfaf 394 Gene3D G3DSA:1.20.1090.10 186 392 6.4E-69 T 15-10-2018 C2I28_01600 5b355022f20902e7c403de812e9082f9 296 PIRSF PIRSF006483 6 295 1.3E-99 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_01600 5b355022f20902e7c403de812e9082f9 296 Gene3D G3DSA:3.30.70.120 205 280 6.4E-26 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_01600 5b355022f20902e7c403de812e9082f9 296 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 25 227 1.9E-68 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_01600 5b355022f20902e7c403de812e9082f9 296 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 233 287 3.6E-23 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_19970 2d0caa93dd7e4c05287a1d2a117c52fa 153 Gene3D G3DSA:3.40.630.30 5 152 1.1E-28 T 15-10-2018 C2I28_19970 2d0caa93dd7e4c05287a1d2a117c52fa 153 Pfam PF00583 Acetyltransferase (GNAT) family 18 142 1.7E-14 T 15-10-2018 IPR000182 GNAT domain C2I28_19970 2d0caa93dd7e4c05287a1d2a117c52fa 153 SUPERFAMILY SSF55729 18 146 7.82E-22 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24615 a5e50f36e59e57fb64b4effb71ad8c16 118 SUPERFAMILY SSF52821 7 118 2.62E-31 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_24615 a5e50f36e59e57fb64b4effb71ad8c16 118 Gene3D G3DSA:3.40.250.10 23 118 3.4E-29 T 15-10-2018 IPR036873 Rhodanese-like domain superfamily C2I28_24615 a5e50f36e59e57fb64b4effb71ad8c16 118 Pfam PF00581 Rhodanese-like domain 31 117 1.6E-16 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_24615 a5e50f36e59e57fb64b4effb71ad8c16 118 SMART SM00450 28 118 2.9E-17 T 15-10-2018 IPR001763 Rhodanese-like domain C2I28_03945 b77763fda6faf59705683c9cff3ec0d6 132 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 23 132 2.0E-11 T 15-10-2018 C2I28_23655 bea94360eb48918af32f5d97bd1c6d32 395 SUPERFAMILY SSF53756 1 387 1.78E-72 T 15-10-2018 C2I28_23655 bea94360eb48918af32f5d97bd1c6d32 395 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 227 369 8.1E-17 T 15-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 C2I28_23655 bea94360eb48918af32f5d97bd1c6d32 395 Gene3D G3DSA:3.40.50.2000 5 386 1.6E-103 T 15-10-2018 C2I28_23655 bea94360eb48918af32f5d97bd1c6d32 395 Gene3D G3DSA:3.40.50.2000 212 375 1.6E-103 T 15-10-2018 C2I28_23655 bea94360eb48918af32f5d97bd1c6d32 395 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 7 389 2.8E-94 T 15-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 C2I28_03305 02f2276a93f4ecc84e96b871df8bf40c 221 SUPERFAMILY SSF141371 100 197 5.49E-6 T 15-10-2018 C2I28_03305 02f2276a93f4ecc84e96b871df8bf40c 221 Gene3D G3DSA:2.40.10.220 101 213 2.0E-9 T 15-10-2018 C2I28_03305 02f2276a93f4ecc84e96b871df8bf40c 221 Pfam PF12945 Flagellar protein YcgR 4 91 1.3E-13 T 15-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal C2I28_03305 02f2276a93f4ecc84e96b871df8bf40c 221 Pfam PF07238 PilZ domain 100 209 1.4E-12 T 15-10-2018 IPR009875 PilZ domain GO:0035438 C2I28_07740 c93f91913a796a614dc5ab86d5142d6c 253 Pfam PF06738 Putative threonine/serine exporter 14 252 6.4E-78 T 15-10-2018 IPR010619 Putative threonine/serine exporter C2I28_26005 72309035112689c3523d0a7e85e1760b 249 PIRSF PIRSF006648 1 249 6.5E-67 T 15-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 C2I28_26005 72309035112689c3523d0a7e85e1760b 249 Pfam PF01061 ABC-2 type transporter 6 214 8.5E-23 T 15-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 C2I28_01885 0b86d2dea17fb9acab815727ab14938b 197 Gene3D G3DSA:3.40.630.30 3 197 2.3E-58 T 15-10-2018 C2I28_01885 0b86d2dea17fb9acab815727ab14938b 197 SUPERFAMILY SSF55729 9 183 9.63E-48 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01885 0b86d2dea17fb9acab815727ab14938b 197 Pfam PF13523 Acetyltransferase (GNAT) domain 28 170 2.9E-44 T 15-10-2018 C2I28_01885 0b86d2dea17fb9acab815727ab14938b 197 SMART SM01006 23 70 5.5E-12 T 15-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain C2I28_21560 d90ff7e64a000558a2b727714062ba03 344 Gene3D G3DSA:3.30.360.10 122 336 2.0E-135 T 15-10-2018 C2I28_21560 d90ff7e64a000558a2b727714062ba03 344 Gene3D G3DSA:3.40.50.720 5 313 2.0E-135 T 15-10-2018 C2I28_21560 d90ff7e64a000558a2b727714062ba03 344 SUPERFAMILY SSF51735 2 198 3.21E-54 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_21560 d90ff7e64a000558a2b727714062ba03 344 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 6.5E-26 T 15-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 C2I28_21560 d90ff7e64a000558a2b727714062ba03 344 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 240 1.2E-19 T 15-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 C2I28_08245 178fc46535aac0e0a17e993cdcabb52b 60 Pfam PF10764 Inhibitor of sigma-G Gin 8 52 1.3E-12 T 15-10-2018 IPR019700 Anti-sigma-G factor Gin C2I28_26505 0899096710ace8899b2e148c2f58489a 503 Pfam PF00501 AMP-binding enzyme 20 406 1.3E-80 T 15-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 C2I28_26505 0899096710ace8899b2e148c2f58489a 503 SUPERFAMILY SSF56801 8 502 4.58E-114 T 15-10-2018 C2I28_26505 0899096710ace8899b2e148c2f58489a 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 494 3.8E-8 T 15-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain C2I28_26505 0899096710ace8899b2e148c2f58489a 503 Gene3D G3DSA:3.30.300.30 400 503 2.6E-17 T 15-10-2018 C2I28_26505 0899096710ace8899b2e148c2f58489a 503 Gene3D G3DSA:3.40.50.12780 6 399 1.4E-95 T 15-10-2018 C2I28_02510 b50d5360eec59cb0e97aef68f8656b9e 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 4 143 1.0E-22 T 15-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 C2I28_02510 b50d5360eec59cb0e97aef68f8656b9e 147 Pfam PF02050 Flagellar FliJ protein 19 142 5.2E-19 T 15-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.4E-46 T 15-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 SUPERFAMILY SSF54999 5 102 1.24E-38 T 15-10-2018 IPR036838 Ribosomal protein S10 domain superfamily C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 15-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.6E-20 T 15-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.6E-20 T 15-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.6E-20 T 15-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.125 T 15-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.0E-36 T 15-10-2018 IPR027486 Ribosomal protein S10 domain C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 SMART SM01403 7 101 2.8E-60 T 15-10-2018 IPR027486 Ribosomal protein S10 domain C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 Gene3D G3DSA:3.30.70.600 1 62 8.6E-21 T 15-10-2018 IPR036838 Ribosomal protein S10 domain superfamily C2I28_08680 434c8f49b795b35c958f072b613dc5b9 102 Gene3D G3DSA:3.30.70.600 65 102 1.3E-14 T 15-10-2018 IPR036838 Ribosomal protein S10 domain superfamily C2I28_16375 470262668ed93deec0441141e5362f79 500 PIRSF PIRSF005690 19 500 7.1E-173 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_16375 470262668ed93deec0441141e5362f79 500 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 33 496 3.4E-177 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_15075 546b1186e2ba55af2fb2da097b5546a0 116 Gene3D G3DSA:1.20.120.440 1 116 5.0E-36 T 15-10-2018 IPR023351 YppE-like superfamily C2I28_15075 546b1186e2ba55af2fb2da097b5546a0 116 SUPERFAMILY SSF140415 2 115 2.75E-28 T 15-10-2018 IPR023351 YppE-like superfamily C2I28_15075 546b1186e2ba55af2fb2da097b5546a0 116 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 9 115 1.2E-34 T 15-10-2018 IPR014913 Protein of unknown function DUF1798 C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 SMART SM00487 155 337 1.5E-17 T 15-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 Gene3D G3DSA:3.40.50.300 342 499 2.4E-23 T 15-10-2018 C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 Gene3D G3DSA:3.40.50.300 158 323 4.5E-17 T 15-10-2018 C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 SUPERFAMILY SSF52540 171 473 3.04E-34 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 Pfam PF04851 Type III restriction enzyme, res subunit 159 306 5.7E-11 T 15-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 Pfam PF00271 Helicase conserved C-terminal domain 362 461 3.9E-10 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_07160 d28dadf1f1e4ade82aef58b5dfebd970 502 SMART SM00490 381 462 6.9E-10 T 15-10-2018 IPR001650 Helicase, C-terminal C2I28_09720 261c130449cef1084421618283b6c7c9 140 Pfam PF07681 DoxX 9 87 4.3E-22 T 15-10-2018 IPR032808 DoxX family C2I28_03580 945eefa5f2c526738dbdff02cb205f2a 305 SUPERFAMILY SSF51430 1 298 3.14E-79 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_03580 945eefa5f2c526738dbdff02cb205f2a 305 Pfam PF00248 Aldo/keto reductase family 16 295 3.1E-63 T 15-10-2018 IPR023210 NADP-dependent oxidoreductase domain C2I28_03580 945eefa5f2c526738dbdff02cb205f2a 305 PRINTS PR00069 Aldo-keto reductase signature 134 151 4.6E-5 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_03580 945eefa5f2c526738dbdff02cb205f2a 305 PRINTS PR00069 Aldo-keto reductase signature 103 121 4.6E-5 T 15-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 C2I28_03580 945eefa5f2c526738dbdff02cb205f2a 305 Gene3D G3DSA:3.20.20.100 1 297 8.2E-105 T 15-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-11 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 Pfam PF03466 LysR substrate binding domain 88 290 5.2E-47 T 15-10-2018 IPR005119 LysR, substrate-binding C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 Gene3D G3DSA:3.40.190.290 92 295 2.7E-56 T 15-10-2018 C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 Gene3D G3DSA:1.10.10.10 1 91 1.2E-27 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 SUPERFAMILY SSF46785 1 86 5.38E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-21 T 15-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 C2I28_23400 5d91cf643f28bc22bfbc734fd4dfdf24 304 SUPERFAMILY SSF53850 89 291 9.87E-42 T 15-10-2018 C2I28_15390 a27646860c05552fcd1b363c0006776e 309 SUPERFAMILY SSF161098 88 291 1.8E-20 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15390 a27646860c05552fcd1b363c0006776e 309 Gene3D G3DSA:1.10.3720.10 83 298 1.6E-21 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15390 a27646860c05552fcd1b363c0006776e 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 2.0E-40 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_06580 4ba929db88e4b07298acd3c58c19b7d9 118 Gene3D G3DSA:3.40.30.10 1 116 4.0E-47 T 15-10-2018 C2I28_06580 4ba929db88e4b07298acd3c58c19b7d9 118 Pfam PF03960 ArsC family 9 115 1.6E-16 T 15-10-2018 IPR006660 Arsenate reductase-like C2I28_06580 4ba929db88e4b07298acd3c58c19b7d9 118 SUPERFAMILY SSF52833 3 117 8.34E-37 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_06580 4ba929db88e4b07298acd3c58c19b7d9 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 117 3.9E-36 T 15-10-2018 IPR006504 Transcriptional regulator Spx/MgsR C2I28_04005 b9ad1fb5c11cdd5b15ecb551cca1d45f 124 Pfam PF14173 ComG operon protein 7 32 123 2.2E-15 T 15-10-2018 IPR020372 Competence operon G protein 7, ComGG C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 SUPERFAMILY SSF47413 7 65 4.74E-10 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 Gene3D G3DSA:1.25.40.10 3 297 1.4E-78 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 SUPERFAMILY SSF48452 132 278 1.06E-15 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 Pfam PF13181 Tetratricopeptide repeat 242 269 0.0098 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 Pfam PF13181 Tetratricopeptide repeat 202 230 0.02 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 SMART SM00028 158 191 200.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 SMART SM00028 201 234 2.4 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 SMART SM00028 241 274 0.11 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_19590 a6aa9f56f07be28a045ccc13a7b1b724 297 SMART SM00028 116 149 290.0 T 15-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 C2I28_12520 552c3c318fe6235a4a3429f42f04361b 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 183 5.2E-15 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_12520 552c3c318fe6235a4a3429f42f04361b 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 70 157 1.7E-6 T 15-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 C2I28_12520 552c3c318fe6235a4a3429f42f04361b 219 SUPERFAMILY SSF56784 1 212 6.2E-51 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_12520 552c3c318fe6235a4a3429f42f04361b 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 2.5E-38 T 15-10-2018 C2I28_12520 552c3c318fe6235a4a3429f42f04361b 219 Gene3D G3DSA:1.10.150.240 15 83 2.4E-53 T 15-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 C2I28_12520 552c3c318fe6235a4a3429f42f04361b 219 Gene3D G3DSA:3.40.50.1000 3 201 2.4E-53 T 15-10-2018 IPR023214 HAD superfamily C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 SUPERFAMILY SSF81338 1 235 5.23E-73 T 15-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 PRINTS PR00783 Major intrinsic protein family signature 213 233 4.8E-51 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 PRINTS PR00783 Major intrinsic protein family signature 2 21 4.8E-51 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 PRINTS PR00783 Major intrinsic protein family signature 81 100 4.8E-51 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 PRINTS PR00783 Major intrinsic protein family signature 136 154 4.8E-51 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 PRINTS PR00783 Major intrinsic protein family signature 44 68 4.8E-51 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 PRINTS PR00783 Major intrinsic protein family signature 166 188 4.8E-51 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 Gene3D G3DSA:1.20.1080.10 1 243 6.8E-78 T 15-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 Pfam PF00230 Major intrinsic protein 2 230 3.0E-49 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 1.1E-64 T 15-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 C2I28_10810 f19894f5d722a35d73d0adf04c67cf11 275 ProSitePatterns PS00221 MIP family signature. 62 70 - T 15-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 C2I28_11800 5bdc6e75ca3eba5487f0fca2d84609ab 229 Gene3D G3DSA:1.10.530.10 56 229 1.1E-52 T 15-10-2018 C2I28_11800 5bdc6e75ca3eba5487f0fca2d84609ab 229 Pfam PF01464 Transglycosylase SLT domain 112 218 1.1E-29 T 15-10-2018 IPR008258 Transglycosylase SLT domain 1 C2I28_11800 5bdc6e75ca3eba5487f0fca2d84609ab 229 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 129 157 - T 15-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 C2I28_11800 5bdc6e75ca3eba5487f0fca2d84609ab 229 SUPERFAMILY SSF53955 105 227 3.44E-47 T 15-10-2018 IPR023346 Lysozyme-like domain superfamily C2I28_16770 01b80546cf082b8299e938738b859b7f 158 Gene3D G3DSA:1.20.120.450 5 149 1.3E-22 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16770 01b80546cf082b8299e938738b859b7f 158 SUPERFAMILY SSF109854 1 157 1.34E-26 T 15-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes C2I28_16770 01b80546cf082b8299e938738b859b7f 158 Pfam PF12867 DinB superfamily 11 142 1.1E-11 T 15-10-2018 IPR024775 DinB-like domain C2I28_04450 c6221a58f49026d6e1a5f6c8de934685 252 Gene3D G3DSA:2.20.25.110 144 207 2.9E-83 T 15-10-2018 C2I28_04450 c6221a58f49026d6e1a5f6c8de934685 252 SUPERFAMILY SSF53335 4 249 2.11E-54 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_04450 c6221a58f49026d6e1a5f6c8de934685 252 Pfam PF13649 Methyltransferase domain 41 136 2.4E-21 T 15-10-2018 C2I28_04450 c6221a58f49026d6e1a5f6c8de934685 252 Gene3D G3DSA:3.40.50.150 6 246 2.9E-83 T 15-10-2018 C2I28_18065 dc20b9c5b197b8c8529026ff14fc79b5 333 Pfam PF01757 Acyltransferase family 6 305 3.9E-19 T 15-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I28_27345 6a01db6896ced3aa5c424f555665a1ac 189 Pfam PF01391 Collagen triple helix repeat (20 copies) 53 96 2.1E-8 T 15-10-2018 IPR008160 Collagen triple helix repeat C2I28_27345 6a01db6896ced3aa5c424f555665a1ac 189 Pfam PF13799 Domain of unknown function (DUF4183) 114 182 1.8E-19 T 15-10-2018 IPR025237 Domain of unknown function DUF4183 C2I28_27345 6a01db6896ced3aa5c424f555665a1ac 189 Gene3D G3DSA:1.20.5.320 71 127 2.9E-9 T 15-10-2018 C2I28_00580 a5f5c4b3cb1652abd22ce3cd79d49765 352 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 330 7.2E-35 T 15-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I28_12145 f425145f855f325791d8a305ca1853d9 399 Gene3D G3DSA:1.20.1250.20 7 391 4.4E-49 T 15-10-2018 C2I28_12145 f425145f855f325791d8a305ca1853d9 399 Pfam PF07690 Major Facilitator Superfamily 21 332 6.4E-42 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_12145 f425145f855f325791d8a305ca1853d9 399 SUPERFAMILY SSF103473 10 392 1.01E-60 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_00315 f9e3d86c16a2c58afdaf66d4e1fb3db1 287 Pfam PF13349 Putative adhesin 46 285 4.1E-25 T 15-10-2018 IPR025164 Putative adhesin C2I28_00315 f9e3d86c16a2c58afdaf66d4e1fb3db1 287 Gene3D G3DSA:2.160.20.120 32 205 1.4E-6 T 15-10-2018 C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.8E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.8E-8 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.1E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.1E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 7.1E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 7.1E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.1E-29 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 SUPERFAMILY SSF51735 2 245 1.04E-60 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 Gene3D G3DSA:3.40.50.720 1 256 4.2E-66 T 15-10-2018 C2I28_21680 de7886ce389f5b00909ea2e1d5d7d21f 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 1.0E-47 T 15-10-2018 C2I28_11480 29b0872aef13d153609056d55bf4551d 559 Gene3D G3DSA:3.40.630.10 9 230 1.3E-29 T 15-10-2018 C2I28_11480 29b0872aef13d153609056d55bf4551d 559 SUPERFAMILY SSF53187 17 530 3.14E-30 T 15-10-2018 C2I28_11480 29b0872aef13d153609056d55bf4551d 559 Pfam PF01546 Peptidase family M20/M25/M40 132 202 2.8E-8 T 15-10-2018 IPR002933 Peptidase M20 GO:0016787 C2I28_11480 29b0872aef13d153609056d55bf4551d 559 PIRSF PIRSF010386 3 556 2.2E-210 T 15-10-2018 IPR012166 Uncharacterised protein family RocB C2I28_17970 19c9e652e5faead5a4d9c32d27df75de 492 Gene3D G3DSA:3.30.70.1450 398 482 3.1E-18 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_17970 19c9e652e5faead5a4d9c32d27df75de 492 Gene3D G3DSA:1.20.1530.20 6 387 1.0E-21 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_17970 19c9e652e5faead5a4d9c32d27df75de 492 SUPERFAMILY SSF116726 395 477 4.84E-13 T 15-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 C2I28_17970 19c9e652e5faead5a4d9c32d27df75de 492 Pfam PF02080 TrkA-C domain 410 477 2.3E-12 T 15-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 C2I28_17970 19c9e652e5faead5a4d9c32d27df75de 492 Pfam PF00999 Sodium/hydrogen exchanger family 11 381 6.6E-60 T 15-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 SUPERFAMILY SSF88946 17 98 5.49E-18 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 Gene3D G3DSA:1.10.1740.10 16 96 4.6E-9 T 15-10-2018 C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 220 4.5E-12 T 15-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 10 236 26.57 T 15-10-2018 IPR014244 RNA polymerase sigma-I type C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 15 235 8.2E-80 T 15-10-2018 IPR014244 RNA polymerase sigma-I type C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 Pfam PF04542 Sigma-70 region 2 29 99 7.1E-12 T 15-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_14190 fe64d9bdd506a9c2a63f9221a32c9b55 236 PIRSF PIRSF038953 2 236 2.6E-64 T 15-10-2018 IPR014244 RNA polymerase sigma-I type C2I28_01800 90c88cfbf27f53dd803d1357b87ac51d 57 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 32 54 4.8E-10 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_01800 90c88cfbf27f53dd803d1357b87ac51d 57 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 35 56 6.7E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_15970 de2443419a3909ee6702fcc68e1ccd8d 449 PIRSF PIRSF000337 3 444 2.1E-155 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_15970 de2443419a3909ee6702fcc68e1ccd8d 449 Pfam PF00296 Luciferase-like monooxygenase 19 383 1.1E-58 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_15970 de2443419a3909ee6702fcc68e1ccd8d 449 SUPERFAMILY SSF51679 4 436 7.2E-128 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_15970 de2443419a3909ee6702fcc68e1ccd8d 449 Gene3D G3DSA:3.20.20.30 1 447 9.2E-158 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_15970 de2443419a3909ee6702fcc68e1ccd8d 449 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 9 430 2.0E-169 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_06415 a05afe091c8a27d90e3b156dea529564 108 Gene3D G3DSA:3.40.30.30 1 105 1.1E-42 T 15-10-2018 IPR038218 YuzD-like superfamily C2I28_06415 a05afe091c8a27d90e3b156dea529564 108 PIRSF PIRSF010603 2 107 1.2E-45 T 15-10-2018 IPR009190 Protein of unknown function DUF1462 C2I28_06415 a05afe091c8a27d90e3b156dea529564 108 Pfam PF07315 Protein of unknown function (DUF1462) 9 101 1.9E-43 T 15-10-2018 IPR009190 Protein of unknown function DUF1462 C2I28_06415 a05afe091c8a27d90e3b156dea529564 108 SUPERFAMILY SSF52833 2 105 1.23E-44 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_04655 eafaa18c24769ef607f61e9d5bdaf72e 309 Gene3D G3DSA:1.10.3720.10 59 291 1.2E-30 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_04655 eafaa18c24769ef607f61e9d5bdaf72e 309 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 11 288 5.0E-77 T 15-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 C2I28_04655 eafaa18c24769ef607f61e9d5bdaf72e 309 SUPERFAMILY SSF161098 20 278 3.38E-38 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_04655 eafaa18c24769ef607f61e9d5bdaf72e 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 291 1.1E-33 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_02745 5234306099bd527ef5006fc88b853161 684 Gene3D G3DSA:2.60.40.2560 605 682 6.3E-23 T 15-10-2018 C2I28_02745 5234306099bd527ef5006fc88b853161 684 SMART SM00220 14 274 6.3E-73 T 15-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I28_02745 5234306099bd527ef5006fc88b853161 684 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 43 - T 15-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 C2I28_02745 5234306099bd527ef5006fc88b853161 684 Gene3D G3DSA:1.10.510.10 95 285 2.2E-54 T 15-10-2018 C2I28_02745 5234306099bd527ef5006fc88b853161 684 SUPERFAMILY SSF56112 10 272 1.35E-84 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_02745 5234306099bd527ef5006fc88b853161 684 Gene3D G3DSA:3.30.10.20 512 576 3.4E-13 T 15-10-2018 C2I28_02745 5234306099bd527ef5006fc88b853161 684 Gene3D G3DSA:3.30.10.20 375 441 2.9E-12 T 15-10-2018 C2I28_02745 5234306099bd527ef5006fc88b853161 684 Pfam PF03793 PASTA domain 514 573 2.1E-10 T 15-10-2018 IPR005543 PASTA domain C2I28_02745 5234306099bd527ef5006fc88b853161 684 Pfam PF03793 PASTA domain 376 436 7.4E-11 T 15-10-2018 IPR005543 PASTA domain C2I28_02745 5234306099bd527ef5006fc88b853161 684 Pfam PF03793 PASTA domain 449 507 1.4E-8 T 15-10-2018 IPR005543 PASTA domain C2I28_02745 5234306099bd527ef5006fc88b853161 684 Gene3D G3DSA:3.30.10.20 442 509 3.1E-10 T 15-10-2018 C2I28_02745 5234306099bd527ef5006fc88b853161 684 Pfam PF00069 Protein kinase domain 14 264 1.1E-54 T 15-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 C2I28_02745 5234306099bd527ef5006fc88b853161 684 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 15-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 C2I28_02745 5234306099bd527ef5006fc88b853161 684 SMART SM00740 508 574 3.0E-14 T 15-10-2018 IPR005543 PASTA domain C2I28_02745 5234306099bd527ef5006fc88b853161 684 SMART SM00740 440 507 0.0026 T 15-10-2018 IPR005543 PASTA domain C2I28_02745 5234306099bd527ef5006fc88b853161 684 SMART SM00740 372 439 1.5E-10 T 15-10-2018 IPR005543 PASTA domain C2I28_02745 5234306099bd527ef5006fc88b853161 684 Gene3D G3DSA:3.30.200.20 3 93 5.5E-32 T 15-10-2018 C2I28_18910 5713e49db6ac19a3ce6d45d07e10c13b 343 Gene3D G3DSA:3.90.550.10 4 205 8.6E-53 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18910 5713e49db6ac19a3ce6d45d07e10c13b 343 Pfam PF00535 Glycosyl transferase family 2 6 141 7.3E-36 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_18910 5713e49db6ac19a3ce6d45d07e10c13b 343 SUPERFAMILY SSF53448 4 230 1.78E-53 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_06650 2b3478132a0c878facb047d83d548f32 290 SUPERFAMILY SSF46689 3 68 2.57E-18 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_06650 2b3478132a0c878facb047d83d548f32 290 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 5.0E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_06650 2b3478132a0c878facb047d83d548f32 290 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 5.0E-10 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_06650 2b3478132a0c878facb047d83d548f32 290 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 4.8E-18 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_06650 2b3478132a0c878facb047d83d548f32 290 Gene3D G3DSA:1.10.357.10 1 194 1.2E-28 T 15-10-2018 C2I28_06650 2b3478132a0c878facb047d83d548f32 290 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 15-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site C2I28_05900 4ba4ca12ba223f32f12bfd5f7af57522 141 Pfam PF05105 Bacteriophage holin family 28 137 7.1E-39 T 15-10-2018 IPR006480 Bacteriophage holin family C2I28_05900 4ba4ca12ba223f32f12bfd5f7af57522 141 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 22 140 4.9E-33 T 15-10-2018 IPR006480 Bacteriophage holin family C2I28_00180 f81347bcbd51da542a5ba2bc873abdaa 565 Pfam PF07690 Major Facilitator Superfamily 26 379 7.6E-25 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_00180 f81347bcbd51da542a5ba2bc873abdaa 565 SUPERFAMILY SSF103473 1 214 5.1E-22 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_00180 f81347bcbd51da542a5ba2bc873abdaa 565 Gene3D G3DSA:1.20.1250.20 4 247 9.8E-22 T 15-10-2018 C2I28_00180 f81347bcbd51da542a5ba2bc873abdaa 565 SUPERFAMILY SSF103473 202 486 2.35E-13 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_20450 f2a9cbecaec6ea2d3e349a596b6bea3e 412 Pfam PF01566 Natural resistance-associated macrophage protein 59 379 2.9E-20 T 15-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 C2I28_22255 ce48f3d564b6eeff87070c726cb85303 410 Gene3D G3DSA:1.20.1250.20 2 390 1.1E-26 T 15-10-2018 C2I28_22255 ce48f3d564b6eeff87070c726cb85303 410 Pfam PF05977 Transmembrane secretion effector 5 400 8.9E-12 T 15-10-2018 IPR010290 Transmembrane secretion effector C2I28_22255 ce48f3d564b6eeff87070c726cb85303 410 SUPERFAMILY SSF103473 5 395 9.42E-31 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_14110 de4cf6788fa7175deaa582f5e0ff9bae 433 PIRSF PIRSF005353 1 433 1.8E-167 T 15-10-2018 IPR026033 Purine permease PbuG-like C2I28_14110 de4cf6788fa7175deaa582f5e0ff9bae 433 Pfam PF00860 Permease family 14 394 5.2E-69 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_14450 24e8f745bb023a91c02d9e18e8195164 281 Pfam PF01734 Patatin-like phospholipase 6 170 1.3E-22 T 15-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 C2I28_14450 24e8f745bb023a91c02d9e18e8195164 281 Gene3D G3DSA:3.40.1090.10 2 91 4.1E-12 T 15-10-2018 C2I28_14450 24e8f745bb023a91c02d9e18e8195164 281 Gene3D G3DSA:3.40.1090.10 92 229 8.1E-17 T 15-10-2018 C2I28_14450 24e8f745bb023a91c02d9e18e8195164 281 SUPERFAMILY SSF52151 4 271 4.45E-51 T 15-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase C2I28_02445 a5abb13e5ec155d7e027ff48c1c3d0ea 258 Pfam PF01311 Bacterial export proteins, family 1 10 244 1.4E-69 T 15-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I28_02445 a5abb13e5ec155d7e027ff48c1c3d0ea 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 177 199 7.6E-27 T 15-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I28_02445 a5abb13e5ec155d7e027ff48c1c3d0ea 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 17 38 7.6E-27 T 15-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I28_02445 a5abb13e5ec155d7e027ff48c1c3d0ea 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 74 93 7.6E-27 T 15-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I28_02445 a5abb13e5ec155d7e027ff48c1c3d0ea 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 199 218 7.6E-27 T 15-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 C2I28_02445 a5abb13e5ec155d7e027ff48c1c3d0ea 258 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 252 2.3E-67 T 15-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 C2I28_20905 6a9f0b7b8c8a9d02d8f16e1567f4f8b2 49 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 36 6.0E-11 T 15-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 C2I28_20905 6a9f0b7b8c8a9d02d8f16e1567f4f8b2 49 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 49 20.339 T 15-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 C2I28_20905 6a9f0b7b8c8a9d02d8f16e1567f4f8b2 49 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 49 6.8E-26 T 15-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 C2I28_20905 6a9f0b7b8c8a9d02d8f16e1567f4f8b2 49 Pfam PF08175 Small acid-soluble spore protein O family 2 49 1.6E-24 T 15-10-2018 C2I28_23010 b01e7b12daf7dec4896165041420e898 443 Pfam PF01943 Polysaccharide biosynthesis protein 4 296 4.1E-25 T 15-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I28_23010 b01e7b12daf7dec4896165041420e898 443 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 348 435 2.1E-8 T 15-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I28_23010 b01e7b12daf7dec4896165041420e898 443 PIRSF PIRSF038958 1 442 4.0E-74 T 15-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I28_24565 3df38279ab97328a75780fec6e39bf8d 204 Gene3D G3DSA:3.40.630.30 3 203 5.4E-45 T 15-10-2018 C2I28_24565 3df38279ab97328a75780fec6e39bf8d 204 Pfam PF13302 Acetyltransferase (GNAT) domain 14 151 4.8E-19 T 15-10-2018 IPR000182 GNAT domain C2I28_24565 3df38279ab97328a75780fec6e39bf8d 204 SUPERFAMILY SSF55729 7 176 5.43E-36 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_04425 311077f2149d425676e332c5cb8183db 44 Pfam PF14141 YqzM-like protein 2 43 1.6E-24 T 15-10-2018 IPR025416 YqzM-like protein C2I28_12280 397458ff4e4e5a1d7dc77929af5cb2a0 229 Pfam PF00005 ABC transporter 21 169 4.2E-35 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_12280 397458ff4e4e5a1d7dc77929af5cb2a0 229 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_12280 397458ff4e4e5a1d7dc77929af5cb2a0 229 SUPERFAMILY SSF52540 1 224 7.1E-74 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_12280 397458ff4e4e5a1d7dc77929af5cb2a0 229 SMART SM00382 30 219 2.1E-12 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_12280 397458ff4e4e5a1d7dc77929af5cb2a0 229 Gene3D G3DSA:3.40.50.300 1 227 2.1E-70 T 15-10-2018 C2I28_20300 fb4c46645bfdc0e379fa30febd5f4c68 272 SUPERFAMILY SSF75011 77 240 2.75E-5 T 15-10-2018 C2I28_05340 b650d594ede824aaafc6e3811132073f 153 Pfam PF03477 ATP cone domain 50 136 1.3E-18 T 15-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 C2I28_05340 b650d594ede824aaafc6e3811132073f 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 84.975 T 15-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 C2I28_05340 b650d594ede824aaafc6e3811132073f 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 2.5E-71 T 15-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 C2I28_06470 b69d228277a10a062f151635733725ab 91 Gene3D G3DSA:3.50.4.20 1 91 1.3E-41 T 15-10-2018 IPR038141 YutD-like superfamily C2I28_06470 b69d228277a10a062f151635733725ab 91 PIRSF PIRSF012565 1 91 1.1E-47 T 15-10-2018 IPR009370 Protein of unknown function DUF1027 C2I28_06470 b69d228277a10a062f151635733725ab 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 1.4E-38 T 15-10-2018 IPR009370 Protein of unknown function DUF1027 C2I28_23645 210db5f2d0dd636572d1b00b46acb30c 369 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 362 5.5E-66 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_23645 210db5f2d0dd636572d1b00b46acb30c 369 Pfam PF03845 Spore germination protein 6 321 4.2E-54 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_13035 3b00491f084b0df99a282a30f2158aff 245 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 4 232 1.0E-91 T 15-10-2018 IPR017792 Urea carboxylase-associated protein 2 C2I28_13035 3b00491f084b0df99a282a30f2158aff 245 Pfam PF09347 Domain of unknown function (DUF1989) 8 179 3.9E-51 T 15-10-2018 IPR018959 Protein of unknown function DUF1989 C2I28_10165 a8ed9485b0db3760c521de5a8c7088af 119 Hamap MF_01502 UPF0295 protein . 2 116 37.039 T 15-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 C2I28_10165 a8ed9485b0db3760c521de5a8c7088af 119 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 4 114 7.0E-48 T 15-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 C2I28_10165 a8ed9485b0db3760c521de5a8c7088af 119 Pfam PF11023 Zinc-ribbon containing domain 4 114 8.7E-62 T 15-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 C2I28_04325 1cced85a35a6d6127a3c1545c77be5da 395 Pfam PF06898 Putative stage IV sporulation protein YqfD 7 385 7.1E-116 T 15-10-2018 IPR010690 Putative stage IV sporulation YqfD C2I28_04325 1cced85a35a6d6127a3c1545c77be5da 395 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 386 3.7E-123 T 15-10-2018 IPR010690 Putative stage IV sporulation YqfD C2I28_04325 1cced85a35a6d6127a3c1545c77be5da 395 PIRSF PIRSF029895 1 395 4.4E-152 T 15-10-2018 IPR010690 Putative stage IV sporulation YqfD C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 Gene3D G3DSA:3.40.1190.20 1 312 4.6E-96 T 15-10-2018 IPR029056 Ribokinase-like C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 PRINTS PR00990 Ribokinase signature 27 46 1.6E-5 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 PRINTS PR00990 Ribokinase signature 221 232 1.6E-5 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 PRINTS PR00990 Ribokinase signature 182 197 1.6E-5 T 15-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 SUPERFAMILY SSF53613 1 307 3.59E-86 T 15-10-2018 IPR029056 Ribokinase-like C2I28_25995 8a691b34ed075995fdfadd9b26287e53 317 Pfam PF00294 pfkB family carbohydrate kinase 3 299 1.2E-66 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_19065 cf1ad2e76c6160d9118378494a2ff2da 93 Gene3D G3DSA:3.30.70.100 3 93 3.9E-29 T 15-10-2018 C2I28_19065 cf1ad2e76c6160d9118378494a2ff2da 93 Pfam PF00708 Acylphosphatase 5 89 4.1E-27 T 15-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 C2I28_19065 cf1ad2e76c6160d9118378494a2ff2da 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 15-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 C2I28_19065 cf1ad2e76c6160d9118378494a2ff2da 93 SUPERFAMILY SSF54975 3 91 1.0E-26 T 15-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 C2I28_22240 83c0ad11831fff3165854970b82301e0 303 Pfam PF00892 EamA-like transporter family 7 138 5.8E-27 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_22240 83c0ad11831fff3165854970b82301e0 303 Pfam PF00892 EamA-like transporter family 153 287 8.0E-22 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_22240 83c0ad11831fff3165854970b82301e0 303 SUPERFAMILY SSF103481 197 290 1.06E-12 T 15-10-2018 C2I28_22240 83c0ad11831fff3165854970b82301e0 303 SUPERFAMILY SSF103481 40 142 1.83E-14 T 15-10-2018 C2I28_21585 c9b0fa3627146eba0452369bbeea5add 192 Pfam PF02342 TerD domain 1 188 3.9E-84 T 15-10-2018 IPR003325 TerD domain C2I28_21585 c9b0fa3627146eba0452369bbeea5add 192 Gene3D G3DSA:2.60.60.30 19 186 7.1E-70 T 15-10-2018 C2I28_24345 a80a4c802364fd36980f7664ce442b36 148 Pfam PF00583 Acetyltransferase (GNAT) family 27 134 3.3E-13 T 15-10-2018 IPR000182 GNAT domain C2I28_24345 a80a4c802364fd36980f7664ce442b36 148 SUPERFAMILY SSF55729 5 138 8.84E-25 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24345 a80a4c802364fd36980f7664ce442b36 148 Gene3D G3DSA:3.40.630.30 1 143 1.6E-24 T 15-10-2018 C2I28_24740 aa762346d1b1ccfba69c1c502c4d89cb 405 SUPERFAMILY SSF103473 7 390 2.49E-61 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_24740 aa762346d1b1ccfba69c1c502c4d89cb 405 Gene3D G3DSA:1.20.1250.20 12 386 8.5E-53 T 15-10-2018 C2I28_24740 aa762346d1b1ccfba69c1c502c4d89cb 405 Pfam PF07690 Major Facilitator Superfamily 19 317 7.9E-36 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_19240 eeb41b6f990f34e354d60d57c74e3e7e 540 PIRSF PIRSF005690 25 518 3.4E-192 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_19240 eeb41b6f990f34e354d60d57c74e3e7e 540 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 41 504 6.0E-194 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_03035 f7f4f7caed3ba61437ab7c038f47669c 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 232 3.7E-42 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_03035 f7f4f7caed3ba61437ab7c038f47669c 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 15-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 C2I28_03035 f7f4f7caed3ba61437ab7c038f47669c 255 SUPERFAMILY SSF52096 7 251 5.13E-58 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_03035 f7f4f7caed3ba61437ab7c038f47669c 255 Gene3D G3DSA:3.90.226.10 4 255 1.5E-59 T 15-10-2018 C2I28_27455 c04d1470e00b3e34e0d2f6aedb6fb9bd 407 Pfam PF00534 Glycosyl transferases group 1 222 379 2.7E-37 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_27455 c04d1470e00b3e34e0d2f6aedb6fb9bd 407 Pfam PF13439 Glycosyltransferase Family 4 14 207 2.8E-16 T 15-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 C2I28_27455 c04d1470e00b3e34e0d2f6aedb6fb9bd 407 Gene3D G3DSA:3.40.50.2000 1 226 7.5E-22 T 15-10-2018 C2I28_27455 c04d1470e00b3e34e0d2f6aedb6fb9bd 407 SUPERFAMILY SSF53756 2 402 9.81E-79 T 15-10-2018 C2I28_27455 c04d1470e00b3e34e0d2f6aedb6fb9bd 407 Gene3D G3DSA:3.40.50.2000 227 384 9.0E-44 T 15-10-2018 C2I28_10970 dc0c977ed6f1861aa23b35e344c6c5a1 386 SUPERFAMILY SSF56059 175 358 1.18E-10 T 15-10-2018 C2I28_10970 dc0c977ed6f1861aa23b35e344c6c5a1 386 Pfam PF14398 YheC/D like ATP-grasp 151 369 7.6E-44 T 15-10-2018 IPR026838 Endospore coat-associated protein YheC/D C2I28_20070 bd4c253dbafa450b0dfeecb585563e10 142 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 140 5.6E-13 T 15-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like C2I28_20070 bd4c253dbafa450b0dfeecb585563e10 142 Gene3D G3DSA:3.30.530.20 1 142 5.6E-42 T 15-10-2018 IPR023393 START-like domain superfamily C2I28_20070 bd4c253dbafa450b0dfeecb585563e10 142 SUPERFAMILY SSF55961 8 141 3.17E-40 T 15-10-2018 C2I28_11425 13427bcddf1ecca7771ba46b4b6903fc 186 Pfam PF10949 Protein of unknown function (DUF2777) 5 181 2.0E-74 T 15-10-2018 IPR024488 Protein of unknown function DUF2777 C2I28_11425 13427bcddf1ecca7771ba46b4b6903fc 186 ProDom PD106196 YISN IG BH1722 6 178 2.0E-36 T 15-10-2018 IPR024488 Protein of unknown function DUF2777 C2I28_04110 194471a99da8b582589ac27ff06117c2 219 Pfam PF01895 PhoU domain 122 206 3.3E-20 T 15-10-2018 IPR026022 PhoU domain C2I28_04110 194471a99da8b582589ac27ff06117c2 219 Pfam PF01895 PhoU domain 18 105 3.9E-20 T 15-10-2018 IPR026022 PhoU domain C2I28_04110 194471a99da8b582589ac27ff06117c2 219 Gene3D G3DSA:1.20.58.220 3 219 7.8E-73 T 15-10-2018 IPR038078 PhoU-like domain superfamily C2I28_04110 194471a99da8b582589ac27ff06117c2 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 214 6.1E-63 T 15-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 C2I28_04110 194471a99da8b582589ac27ff06117c2 219 SUPERFAMILY SSF109755 4 218 1.36E-63 T 15-10-2018 C2I28_04110 194471a99da8b582589ac27ff06117c2 219 PIRSF PIRSF003107 1 219 1.2E-62 T 15-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 C2I28_01255 49e15793ef746ff02c890e4c7fc08e0b 254 Pfam PF01925 Sulfite exporter TauE/SafE 6 253 7.2E-45 T 15-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I28_16820 33b8dbb4795abc5bf04ece08739ddbe8 69 Pfam PF04892 VanZ like family 5 42 6.7E-10 T 15-10-2018 IPR006976 VanZ-like C2I28_03730 5860335e990f3da83472032588deddb3 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 1.1E-62 T 15-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I28_03730 5860335e990f3da83472032588deddb3 145 Pfam PF06491 Disulphide isomerase 8 142 1.8E-61 T 15-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family C2I28_03730 5860335e990f3da83472032588deddb3 145 Gene3D G3DSA:3.40.30.10 25 142 5.2E-53 T 15-10-2018 C2I28_00810 7e52a8c135bc78ef8bf328d52b3c33d0 292 Gene3D G3DSA:3.40.50.1580 39 290 1.5E-80 T 15-10-2018 C2I28_00810 7e52a8c135bc78ef8bf328d52b3c33d0 292 SUPERFAMILY SSF53167 43 271 7.17E-43 T 15-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I28_00810 7e52a8c135bc78ef8bf328d52b3c33d0 292 Pfam PF01048 Phosphorylase superfamily 43 265 2.9E-35 T 15-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 Gene3D G3DSA:1.10.10.10 1 142 2.3E-33 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 Pfam PF01047 MarR family 30 85 1.5E-16 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 SUPERFAMILY SSF46785 4 136 1.47E-30 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 SMART SM00347 22 121 5.7E-29 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 5.5E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 5.5E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_00680 57da49575c3f21f68784a74ed63daedf 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 5.5E-10 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_10475 f8cda022092485303bca696234b48f1e 245 Gene3D G3DSA:3.20.20.190 2 244 1.4E-74 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_10475 f8cda022092485303bca696234b48f1e 245 SUPERFAMILY SSF51695 6 239 7.33E-69 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_10475 f8cda022092485303bca696234b48f1e 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 10 236 1.9E-43 T 15-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I28_04460 2e016d0f0470bc840c18b386211de8eb 190 SUPERFAMILY SSF109604 6 180 1.14E-36 T 15-10-2018 C2I28_04460 2e016d0f0470bc840c18b386211de8eb 190 Pfam PF01966 HD domain 18 130 1.4E-16 T 15-10-2018 IPR006674 HD domain C2I28_04460 2e016d0f0470bc840c18b386211de8eb 190 SMART SM00471 14 141 5.7E-11 T 15-10-2018 IPR003607 HD/PDEase domain C2I28_04460 2e016d0f0470bc840c18b386211de8eb 190 Gene3D G3DSA:1.10.3210.10 1 184 1.1E-60 T 15-10-2018 C2I28_04460 2e016d0f0470bc840c18b386211de8eb 190 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 1.4E-69 T 15-10-2018 IPR005249 Conserved hypothetical protein CHP00488 C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 8 495 3.8E-72 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 Pfam PF03023 MviN-like protein 29 452 2.6E-65 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 PRINTS PR01806 Virulence factor MviN signature 251 277 4.7E-19 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 PRINTS PR01806 Virulence factor MviN signature 34 53 4.7E-19 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 PRINTS PR01806 Virulence factor MviN signature 349 368 4.7E-19 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 PRINTS PR01806 Virulence factor MviN signature 401 418 4.7E-19 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_07700 c7e088c55d1618a1bd943d935808db5a 500 PRINTS PR01806 Virulence factor MviN signature 128 152 4.7E-19 T 15-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ C2I28_26925 ff226dc2428e00b54ecd8bf0091d23aa 304 Gene3D G3DSA:3.40.91.100 135 299 8.3E-8 T 15-10-2018 C2I28_26925 ff226dc2428e00b54ecd8bf0091d23aa 304 SUPERFAMILY SSF52980 166 284 1.72E-15 T 15-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 C2I28_26925 ff226dc2428e00b54ecd8bf0091d23aa 304 Pfam PF14338 Mrr N-terminal domain 6 91 4.4E-29 T 15-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain C2I28_26925 ff226dc2428e00b54ecd8bf0091d23aa 304 Pfam PF04471 Restriction endonuclease 162 278 1.4E-32 T 15-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 C2I28_01400 14d939f05e7d086e3a82076cb21a8c6e 132 SUPERFAMILY SSF55729 17 123 4.32E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01400 14d939f05e7d086e3a82076cb21a8c6e 132 Pfam PF13673 Acetyltransferase (GNAT) domain 14 126 9.3E-16 T 15-10-2018 IPR000182 GNAT domain C2I28_01400 14d939f05e7d086e3a82076cb21a8c6e 132 Gene3D G3DSA:3.40.630.30 2 127 1.5E-24 T 15-10-2018 C2I28_22890 2a544885c12ba51bef5c1684729aa124 247 Gene3D G3DSA:3.20.20.150 1 247 1.6E-59 T 15-10-2018 C2I28_22890 2a544885c12ba51bef5c1684729aa124 247 SUPERFAMILY SSF51658 1 229 6.53E-41 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_07680 33f85568b5d33569081342d507dfcaf1 312 Gene3D G3DSA:3.90.550.10 1 234 1.3E-42 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_07680 33f85568b5d33569081342d507dfcaf1 312 Pfam PF00535 Glycosyl transferase family 2 5 157 1.6E-17 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_07680 33f85568b5d33569081342d507dfcaf1 312 SUPERFAMILY SSF53448 1 251 6.59E-33 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_16780 60ba0368baa7256da7284e5b25875d55 368 SUPERFAMILY SSF69572 88 362 1.83E-56 T 15-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 C2I28_16780 60ba0368baa7256da7284e5b25875d55 368 Gene3D G3DSA:3.40.50.720 99 362 1.5E-64 T 15-10-2018 C2I28_16780 60ba0368baa7256da7284e5b25875d55 368 Pfam PF00899 ThiF family 119 335 1.1E-41 T 15-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 C2I28_20280 77db1d10db4b6ce9c766efe8dceedd3a 320 Pfam PF04294 VanW like protein 184 312 1.1E-47 T 15-10-2018 IPR007391 Vancomycin resistance VanW C2I28_01290 c25e50bc13cd0d8c1aed1cbac8b09e21 193 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 5 185 1.1E-36 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_09065 57e623132301ce64c45af0d48104fc3f 268 Gene3D G3DSA:1.10.3720.10 6 262 9.0E-42 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_09065 57e623132301ce64c45af0d48104fc3f 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 250 3.5E-16 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_09065 57e623132301ce64c45af0d48104fc3f 268 SUPERFAMILY SSF161098 3 252 7.85E-51 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_24620 77caa19bc38f04a5323b43c5d9b13d07 160 Gene3D G3DSA:3.40.1260.10 2 160 5.5E-67 T 15-10-2018 IPR027396 DsrEFH-like C2I28_24620 77caa19bc38f04a5323b43c5d9b13d07 160 SUPERFAMILY SSF75169 6 158 5.3E-22 T 15-10-2018 IPR027396 DsrEFH-like C2I28_24620 77caa19bc38f04a5323b43c5d9b13d07 160 Pfam PF13686 DsrE/DsrF/DrsH-like family 5 159 1.8E-68 T 15-10-2018 IPR032836 DsrE2-like family C2I28_01960 94bf4cea93a264e3f2a571cdad6ef154 185 Hamap MF_01515 UPF0316 protein . 1 169 28.852 T 15-10-2018 IPR022930 Protein of unknown function UPF0316 C2I28_01960 94bf4cea93a264e3f2a571cdad6ef154 185 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 109 161 4.2E-7 T 15-10-2018 IPR019264 Domain of unknown function DUF2179 C2I28_15380 3cb3073720149ba887b9444f66870326 431 Pfam PF00860 Permease family 4 386 2.5E-54 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_22015 b656ec38a94662e18bcde852ebfa19be 282 SUPERFAMILY SSF56281 6 269 7.08E-31 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_22015 b656ec38a94662e18bcde852ebfa19be 282 Gene3D G3DSA:3.60.15.10 8 282 3.9E-88 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_22015 b656ec38a94662e18bcde852ebfa19be 282 SMART SM00849 48 265 9.0E-15 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_22015 b656ec38a94662e18bcde852ebfa19be 282 Pfam PF00753 Metallo-beta-lactamase superfamily 47 137 1.1E-12 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_24015 b5c29fda5167d60d1f1ae491dc89ccda 318 SUPERFAMILY SSF53807 46 302 2.08E-69 T 15-10-2018 C2I28_24015 b5c29fda5167d60d1f1ae491dc89ccda 318 Gene3D G3DSA:3.40.50.1980 50 306 2.5E-99 T 15-10-2018 C2I28_24015 b5c29fda5167d60d1f1ae491dc89ccda 318 Gene3D G3DSA:3.40.50.12260 187 292 2.5E-99 T 15-10-2018 C2I28_24015 b5c29fda5167d60d1f1ae491dc89ccda 318 Pfam PF01497 Periplasmic binding protein 59 292 1.7E-40 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_09690 d3bfad75f715b7c1f01eba18694de56c 227 Pfam PF01061 ABC-2 type transporter 14 197 8.9E-10 T 15-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 395 419 - T 15-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 Gene3D G3DSA:3.60.20.40 395 573 2.2E-70 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 Gene3D G3DSA:1.10.246.130 268 394 1.1E-44 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 39 566 1.6E-178 T 15-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 SUPERFAMILY SSF56235 36 574 5.98E-179 T 15-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 474 491 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 252 268 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 61 86 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 154 173 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 419 437 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 450 465 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 136 154 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 282 301 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 395 413 3.5E-71 T 15-10-2018 C2I28_01080 ab5b44ce717e90ff319266ea6fb9ce69 692 Pfam PF01019 Gamma-glutamyltranspeptidase 54 569 6.8E-174 T 15-10-2018 C2I28_18865 3c54341c833fd85484c4c1ca298d4dc0 297 SUPERFAMILY SSF53448 3 233 2.37E-33 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_18865 3c54341c833fd85484c4c1ca298d4dc0 297 Pfam PF00535 Glycosyl transferase family 2 6 136 4.4E-23 T 15-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 C2I28_18865 3c54341c833fd85484c4c1ca298d4dc0 297 Gene3D G3DSA:3.90.550.10 1 239 4.8E-31 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_19325 982eb2ddb4d654535d4b6272fc825c0b 725 Pfam PF13515 Fusaric acid resistance protein-like 402 526 1.4E-15 T 15-10-2018 C2I28_19325 982eb2ddb4d654535d4b6272fc825c0b 725 SUPERFAMILY SSF103473 368 524 4.84E-5 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_17310 b07ae2e32cb102dfc1b076921990f6ad 199 Gene3D G3DSA:1.20.120.80 14 199 4.6E-55 T 15-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17310 b07ae2e32cb102dfc1b076921990f6ad 199 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 20 199 2.5E-68 T 15-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 C2I28_17310 b07ae2e32cb102dfc1b076921990f6ad 199 Pfam PF00510 Cytochrome c oxidase subunit III 11 197 1.8E-17 T 15-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17310 b07ae2e32cb102dfc1b076921990f6ad 199 SUPERFAMILY SSF81452 7 197 1.96E-54 T 15-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17260 e7453f26b8009b90523411c44a2ff1e0 134 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 127 8.2E-19 T 15-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 C2I28_17260 e7453f26b8009b90523411c44a2ff1e0 134 Pfam PF03061 Thioesterase superfamily 47 120 1.2E-12 T 15-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 C2I28_17260 e7453f26b8009b90523411c44a2ff1e0 134 SUPERFAMILY SSF54637 12 133 2.26E-28 T 15-10-2018 IPR029069 HotDog domain superfamily C2I28_17260 e7453f26b8009b90523411c44a2ff1e0 134 Gene3D G3DSA:3.10.129.10 6 134 1.2E-36 T 15-10-2018 C2I28_15580 590ad7af939605dbf24b78c0138d9687 246 Pfam PF01323 DSBA-like thioredoxin domain 2 206 3.3E-47 T 15-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 C2I28_15580 590ad7af939605dbf24b78c0138d9687 246 SUPERFAMILY SSF52833 1 212 1.26E-50 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_15580 590ad7af939605dbf24b78c0138d9687 246 Gene3D G3DSA:3.40.30.10 1 209 5.0E-82 T 15-10-2018 C2I28_17865 f266ddff38ed36b0bf191d0e68b94a31 115 SUPERFAMILY SSF89442 2 114 7.19E-53 T 15-10-2018 IPR036492 Hypothetical protein YojF superfamily C2I28_17865 f266ddff38ed36b0bf191d0e68b94a31 115 Gene3D G3DSA:2.70.180.10 1 115 9.0E-52 T 15-10-2018 IPR036492 Hypothetical protein YojF superfamily C2I28_17865 f266ddff38ed36b0bf191d0e68b94a31 115 Pfam PF08830 Protein of unknown function (DUF1806) 3 114 2.8E-54 T 15-10-2018 IPR014934 Protein of unknown function DUF1806 C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 PRINTS PR01543 Arylamine N-acetyltransferase signature 19 42 1.1E-13 T 15-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 PRINTS PR01543 Arylamine N-acetyltransferase signature 43 66 1.1E-13 T 15-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 PRINTS PR01543 Arylamine N-acetyltransferase signature 67 89 1.1E-13 T 15-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 PRINTS PR01543 Arylamine N-acetyltransferase signature 99 124 1.1E-13 T 15-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 Pfam PF00797 N-acetyltransferase 21 246 5.1E-63 T 15-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 SUPERFAMILY SSF54001 2 246 1.8E-69 T 15-10-2018 IPR038765 Papain-like cysteine peptidase superfamily C2I28_11980 4413e7d7622f9474a1c01608715f6a0b 251 Gene3D G3DSA:3.30.2140.20 2 247 4.6E-79 T 15-10-2018 C2I28_25635 b0559e1682a912e61e3f096a107c5f93 126 SUPERFAMILY SSF54593 1 121 9.49E-26 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_25635 b0559e1682a912e61e3f096a107c5f93 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 121 1.5E-8 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_25635 b0559e1682a912e61e3f096a107c5f93 126 Gene3D G3DSA:3.10.180.10 6 126 1.5E-39 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 Gene3D G3DSA:1.10.490.50 159 248 2.8E-22 T 15-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 Pfam PF07739 TipAS antibiotic-recognition domain 130 242 5.8E-35 T 15-10-2018 IPR012925 TipAS antibiotic-recognition domain C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 SMART SM00422 4 72 1.9E-25 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 Gene3D G3DSA:1.10.1660.10 2 139 4.0E-50 T 15-10-2018 C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 SUPERFAMILY SSF46955 5 114 1.98E-28 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 Pfam PF13411 MerR HTH family regulatory protein 4 69 5.5E-16 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_23615 95da61ab534781fb38d6c6a3380b4bf9 249 SUPERFAMILY SSF89082 159 246 1.83E-28 T 15-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain C2I28_23110 3605e312d49bf60e30d41b8e36be59ec 323 Pfam PF10503 Esterase PHB depolymerase 38 240 1.2E-55 T 15-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 C2I28_23110 3605e312d49bf60e30d41b8e36be59ec 323 Gene3D G3DSA:3.40.50.1820 9 322 2.6E-59 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_23110 3605e312d49bf60e30d41b8e36be59ec 323 SUPERFAMILY SSF53474 31 318 4.2E-37 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_23110 3605e312d49bf60e30d41b8e36be59ec 323 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 39 235 1.2E-48 T 15-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 C2I28_03720 07831c84244252cc6866041e488c6ed8 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 5.1E-22 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_03720 07831c84244252cc6866041e488c6ed8 219 SUPERFAMILY SSF161098 13 217 5.49E-46 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_03720 07831c84244252cc6866041e488c6ed8 219 Gene3D G3DSA:1.10.3720.10 1 219 5.7E-59 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_03720 07831c84244252cc6866041e488c6ed8 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 1.3E-31 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 SMART SM00347 30 130 1.6E-22 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 Gene3D G3DSA:1.10.10.10 1 146 1.4E-37 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 SUPERFAMILY SSF46785 11 145 2.09E-31 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 Pfam PF01047 MarR family 37 95 1.6E-15 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 3.6E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 3.6E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_05085 23816f2c470b1691cfd72ed0ccff973d 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 3.6E-7 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_11580 f1268a018e9b057d0ea7ee14c073f546 214 Pfam PF13460 NAD(P)H-binding 7 189 3.8E-48 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_11580 f1268a018e9b057d0ea7ee14c073f546 214 Gene3D G3DSA:3.40.50.720 1 213 7.7E-61 T 15-10-2018 C2I28_11580 f1268a018e9b057d0ea7ee14c073f546 214 SUPERFAMILY SSF51735 1 200 3.49E-45 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_25030 a6d50370b65f7eea85f74a1453e87658 284 Pfam PF01969 Protein of unknown function DUF111 4 282 4.4E-95 T 15-10-2018 IPR002822 Nickel insertion protein C2I28_08870 cc27c65548e4d87ce3f99eac7f978a44 357 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 107 344 6.2E-84 T 15-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 C2I28_08870 cc27c65548e4d87ce3f99eac7f978a44 357 ProSitePatterns PS01215 Mrp family signature. 210 226 - T 15-10-2018 IPR000808 Mrp, conserved site GO:0005524 C2I28_08870 cc27c65548e4d87ce3f99eac7f978a44 357 SUPERFAMILY SSF52540 102 313 3.34E-44 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_08870 cc27c65548e4d87ce3f99eac7f978a44 357 Gene3D G3DSA:3.40.50.300 102 321 4.2E-65 T 15-10-2018 C2I28_08870 cc27c65548e4d87ce3f99eac7f978a44 357 Hamap MF_02040 Iron-sulfur cluster carrier protein. 98 345 33.707 T 15-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein C2I28_10790 290525114a1269a9ef48cfd47f029e74 264 Pfam PF13624 SurA N-terminal domain 68 185 2.4E-19 T 15-10-2018 C2I28_10790 290525114a1269a9ef48cfd47f029e74 264 SUPERFAMILY SSF109998 69 243 1.37E-27 T 15-10-2018 IPR027304 Trigger factor/SurA domain superfamily C2I28_10790 290525114a1269a9ef48cfd47f029e74 264 Gene3D G3DSA:1.10.4030.30 67 263 1.7E-26 T 15-10-2018 C2I28_17950 b445f8ef17bfa31d0ca7cc677522c944 381 PIRSF PIRSF026508 7 381 1.8E-114 T 15-10-2018 IPR008863 Toxic anion resistance C2I28_17950 b445f8ef17bfa31d0ca7cc677522c944 381 Pfam PF05816 Toxic anion resistance protein (TelA) 50 378 4.1E-122 T 15-10-2018 IPR008863 Toxic anion resistance C2I28_09175 13c95ca0a05db3b65cc6253421d0a4f7 110 Pfam PF01740 STAS domain 5 103 2.7E-17 T 15-10-2018 IPR002645 STAS domain C2I28_09175 13c95ca0a05db3b65cc6253421d0a4f7 110 SUPERFAMILY SSF52091 3 107 1.96E-26 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09175 13c95ca0a05db3b65cc6253421d0a4f7 110 Gene3D G3DSA:3.30.750.24 1 110 3.2E-29 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_09175 13c95ca0a05db3b65cc6253421d0a4f7 110 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 5.3E-33 T 15-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 C2I28_18190 6c1e5216e137a509853707c948940497 300 Gene3D G3DSA:3.40.630.30 17 218 3.6E-17 T 15-10-2018 C2I28_18190 6c1e5216e137a509853707c948940497 300 SUPERFAMILY SSF55729 2 285 4.87E-22 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_18190 6c1e5216e137a509853707c948940497 300 Pfam PF00583 Acetyltransferase (GNAT) family 41 133 2.2E-10 T 15-10-2018 IPR000182 GNAT domain C2I28_20200 b0d9e7db68ee2a12d0e076dca9c803b9 186 Pfam PF00881 Nitroreductase family 7 166 3.7E-24 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_20200 b0d9e7db68ee2a12d0e076dca9c803b9 186 PIRSF PIRSF000232 1 186 2.2E-46 T 15-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like C2I28_20200 b0d9e7db68ee2a12d0e076dca9c803b9 186 Gene3D G3DSA:3.40.109.10 1 184 5.7E-43 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_20200 b0d9e7db68ee2a12d0e076dca9c803b9 186 SUPERFAMILY SSF55469 1 175 1.13E-32 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_06960 f5443d06e2870fe792ae2445d95d7872 121 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 5 108 1.6E-28 T 15-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV C2I28_05485 bdc8b21a56ceb462d1a9a5e8fd964b44 226 Pfam PF13483 Beta-lactamase superfamily domain 4 192 3.4E-26 T 15-10-2018 C2I28_05485 bdc8b21a56ceb462d1a9a5e8fd964b44 226 SUPERFAMILY SSF56281 1 213 3.28E-34 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_05485 bdc8b21a56ceb462d1a9a5e8fd964b44 226 SMART SM00849 8 192 3.0E-10 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_05485 bdc8b21a56ceb462d1a9a5e8fd964b44 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 226 38.571 T 15-10-2018 IPR022877 Protein of unknown funcion UPF0173 C2I28_05485 bdc8b21a56ceb462d1a9a5e8fd964b44 226 Gene3D G3DSA:3.60.15.10 2 226 1.6E-73 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_06355 ff4334af7437ac7cf12144d65a9efcfb 439 Pfam PF03553 Na+/H+ antiporter family 150 433 7.0E-69 T 15-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I28_06355 ff4334af7437ac7cf12144d65a9efcfb 439 Pfam PF13726 Na+-H+ antiporter family 2 88 3.3E-31 T 15-10-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal C2I28_06720 c0179ffde571ebab594c5808358e0cbe 77 Gene3D G3DSA:3.10.20.30 1 77 3.1E-21 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_06720 c0179ffde571ebab594c5808358e0cbe 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 5.8E-25 T 15-10-2018 C2I28_06720 c0179ffde571ebab594c5808358e0cbe 77 Pfam PF02597 ThiS family 4 77 1.6E-17 T 15-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 C2I28_06720 c0179ffde571ebab594c5808358e0cbe 77 SUPERFAMILY SSF54285 1 77 3.92E-17 T 15-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 PIRSF PIRSF010376 2 286 1.7E-97 T 15-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 35.988 T 15-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 Gene3D G3DSA:3.30.70.890 162 286 9.9E-29 T 15-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 SUPERFAMILY SSF54211 3 157 4.71E-48 T 15-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 3 287 4.0E-113 T 15-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 SUPERFAMILY SSF55060 161 281 1.93E-31 T 15-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 Pfam PF00288 GHMP kinases N terminal domain 87 144 1.8E-11 T 15-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 Gene3D G3DSA:3.30.230.10 1 158 8.5E-60 T 15-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup C2I28_08335 575d0b7dc0f710274b0f0cc269653f35 289 Pfam PF08544 GHMP kinases C terminal 197 270 5.2E-8 T 15-10-2018 IPR013750 GHMP kinase, C-terminal domain C2I28_16905 e9953ab8a6cea5c212ca92bc8602d992 191 Gene3D G3DSA:1.10.357.10 74 191 2.5E-26 T 15-10-2018 C2I28_16905 e9953ab8a6cea5c212ca92bc8602d992 191 Gene3D G3DSA:1.10.10.60 1 65 2.6E-25 T 15-10-2018 C2I28_16905 e9953ab8a6cea5c212ca92bc8602d992 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 9.6E-12 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_16905 e9953ab8a6cea5c212ca92bc8602d992 191 Pfam PF16925 Bacterial transcriptional repressor C-terminal 99 188 1.6E-7 T 15-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal C2I28_16905 e9953ab8a6cea5c212ca92bc8602d992 191 SUPERFAMILY SSF46689 2 67 1.28E-14 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_16905 e9953ab8a6cea5c212ca92bc8602d992 191 SUPERFAMILY SSF48498 81 190 1.03E-21 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_25760 4877a6b69b666823535bc7aa77e6447b 183 Gene3D G3DSA:2.60.40.1240 42 183 6.1E-43 T 15-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily C2I28_25760 4877a6b69b666823535bc7aa77e6447b 183 Pfam PF11611 Domain of unknown function (DUF4352) 49 166 2.4E-12 T 15-10-2018 IPR029051 Domain of unknown function DUF4352 C2I28_18430 c2f1bdb0056256a3d5e5cec2bdefe65c 288 SUPERFAMILY SSF161098 25 279 1.1E-53 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18430 c2f1bdb0056256a3d5e5cec2bdefe65c 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 282 2.5E-12 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_18430 c2f1bdb0056256a3d5e5cec2bdefe65c 288 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 27 286 2.2E-123 T 15-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 C2I28_18430 c2f1bdb0056256a3d5e5cec2bdefe65c 288 Gene3D G3DSA:1.10.3720.10 28 286 9.7E-62 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18430 c2f1bdb0056256a3d5e5cec2bdefe65c 288 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 25 283 1.5E-94 T 15-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 C2I28_02595 7333b98eb8ec1e83ee36c8efc8c6786e 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 72 250 37.912 T 15-10-2018 IPR022898 Ribonuclease HII GO:0004523 C2I28_02595 7333b98eb8ec1e83ee36c8efc8c6786e 255 SUPERFAMILY SSF53098 61 254 7.13E-71 T 15-10-2018 IPR012337 Ribonuclease H-like superfamily C2I28_02595 7333b98eb8ec1e83ee36c8efc8c6786e 255 Pfam PF01351 Ribonuclease HII 74 248 6.0E-38 T 15-10-2018 IPR024567 Ribonuclease HII/HIII domain C2I28_02595 7333b98eb8ec1e83ee36c8efc8c6786e 255 Gene3D G3DSA:3.30.420.10 48 255 2.1E-80 T 15-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 Pfam PF01047 MarR family 28 85 2.4E-13 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 7.7E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 7.7E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 7.7E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 7.7E-12 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 SUPERFAMILY SSF46785 4 142 5.04E-31 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 60 94 - T 15-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 SMART SM00347 21 121 2.7E-19 T 15-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 C2I28_16085 2cf1cb100bd52cb01217b4584ddabd33 150 Gene3D G3DSA:1.10.10.10 2 145 3.6E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_07930 f7cac5d13b38356e5ec3ebf8913dcd8c 166 Gene3D G3DSA:2.40.50.140 1 110 4.0E-47 T 15-10-2018 C2I28_07930 f7cac5d13b38356e5ec3ebf8913dcd8c 166 SUPERFAMILY SSF50249 1 166 1.99E-59 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_07930 f7cac5d13b38356e5ec3ebf8913dcd8c 166 Pfam PF00436 Single-strand binding protein family 2 103 4.2E-39 T 15-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 C2I28_07930 f7cac5d13b38356e5ec3ebf8913dcd8c 166 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 166 2.1E-50 T 15-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I28_07930 f7cac5d13b38356e5ec3ebf8913dcd8c 166 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.641 T 15-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 C2I28_03585 e7a2600341477b26cb37708a5c8119d9 82 Pfam PF13025 Protein of unknown function (DUF3886) 12 77 5.7E-17 T 15-10-2018 IPR024980 Protein of unknown function DUF3886 C2I28_18260 2a718544f0331cad3731b31f63574b86 144 Pfam PF13411 MerR HTH family regulatory protein 5 71 1.5E-18 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_18260 2a718544f0331cad3731b31f63574b86 144 SMART SM00422 4 74 3.1E-29 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_18260 2a718544f0331cad3731b31f63574b86 144 Gene3D G3DSA:1.10.1660.10 3 143 8.4E-29 T 15-10-2018 C2I28_18260 2a718544f0331cad3731b31f63574b86 144 SUPERFAMILY SSF46955 4 112 8.06E-25 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_12720 057810adfcf0dc49405e9aa0bcf63714 113 Pfam PF04341 Protein of unknown function, DUF485 25 108 6.3E-25 T 15-10-2018 IPR007436 Protein of unknown function DUF485 C2I28_27490 1d42d45d3bc90f8310d6755e80e0c5a8 231 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 17 182 2.5E-23 T 15-10-2018 IPR014903 Protein of unknown function DUF1796 C2I28_20530 635393d7c71e088e1a86c84ad8ff9b28 334 Gene3D G3DSA:1.20.1260.10 2 146 3.3E-11 T 15-10-2018 IPR012347 Ferritin-like C2I28_20530 635393d7c71e088e1a86c84ad8ff9b28 334 Gene3D G3DSA:1.20.1260.10 199 317 4.9E-8 T 15-10-2018 IPR012347 Ferritin-like C2I28_20530 635393d7c71e088e1a86c84ad8ff9b28 334 Pfam PF11553 Protein of unknown function (DUF3231) 169 329 3.6E-40 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_20530 635393d7c71e088e1a86c84ad8ff9b28 334 Pfam PF11553 Protein of unknown function (DUF3231) 3 155 2.0E-44 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_26725 894f551f9b1626f4b6137dbc3bd0066a 289 Gene3D G3DSA:3.40.630.30 7 132 1.5E-15 T 15-10-2018 C2I28_26725 894f551f9b1626f4b6137dbc3bd0066a 289 Gene3D G3DSA:3.40.630.90 137 289 4.2E-10 T 15-10-2018 C2I28_26725 894f551f9b1626f4b6137dbc3bd0066a 289 SUPERFAMILY SSF55729 12 268 1.02E-32 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_26725 894f551f9b1626f4b6137dbc3bd0066a 289 Pfam PF13673 Acetyltransferase (GNAT) domain 36 127 6.8E-9 T 15-10-2018 IPR000182 GNAT domain C2I28_18990 dc2ce1f5722d7c8b081e629e3fa8a814 89 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 18 84 4.8E-16 T 15-10-2018 IPR008792 Coenzyme PQQ synthesis D C2I28_18990 dc2ce1f5722d7c8b081e629e3fa8a814 89 Gene3D G3DSA:1.10.10.1150 10 85 7.2E-8 T 15-10-2018 C2I28_25035 256759cdeae421cf38a0193b9b0db999 256 SUPERFAMILY SSF52255 114 246 1.83E-31 T 15-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 C2I28_25035 256759cdeae421cf38a0193b9b0db999 256 SMART SM01001 114 246 3.2E-39 T 15-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I28_25035 256759cdeae421cf38a0193b9b0db999 256 Gene3D G3DSA:3.40.50.7700 115 255 1.1E-36 T 15-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 C2I28_25035 256759cdeae421cf38a0193b9b0db999 256 Pfam PF00731 AIR carboxylase 116 241 1.9E-16 T 15-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 Gene3D G3DSA:3.40.50.300 4 279 3.2E-43 T 15-10-2018 C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 Pfam PF00005 ABC transporter 40 171 1.9E-18 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 SMART SM00382 49 228 2.6E-8 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 SUPERFAMILY SSF52540 24 237 4.13E-42 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 Gene3D G3DSA:2.30.30.40 349 424 3.2E-9 T 15-10-2018 C2I28_13775 cbdf47927fdad70d3796fd347bfb7295 562 Pfam PF08239 Bacterial SH3 domain 365 419 1.1E-8 T 15-10-2018 IPR003646 SH3-like domain, bacterial-type C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 Pfam PF01545 Cation efflux family 17 224 4.8E-28 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 308 6.9E-38 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 Gene3D G3DSA:1.20.1510.10 11 226 2.5E-24 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 Gene3D G3DSA:3.30.70.1350 230 308 3.5E-10 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 SUPERFAMILY SSF160240 232 307 1.14E-13 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 SUPERFAMILY SSF161111 10 229 1.57E-29 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_02045 d8598ad0c1db4c2d64baaf7187499b71 325 Pfam PF16916 Dimerisation domain of Zinc Transporter 233 305 3.2E-12 T 15-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain C2I28_02895 7ac37c4933abb6da553edb3ae84f287c 89 Pfam PF02325 YGGT family 11 76 2.5E-23 T 15-10-2018 IPR003425 CCB3/YggT GO:0016020 C2I28_21840 213181199a362d836e07974e738e1bdf 130 Pfam PF15594 Immunity protein 50 9 124 5.6E-28 T 15-10-2018 IPR028957 Immunity protein 50 C2I28_10545 ee32621fd052d5f246f25bd8a352e41e 40 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 14 36 8.0E-14 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_10545 ee32621fd052d5f246f25bd8a352e41e 40 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 12 36 2.4E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_22525 0a732b77af341ba3797887b43ddaef74 63 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 60 2.5E-11 T 15-10-2018 IPR027379 Cardiolipin synthase N-terminal C2I28_01790 eee2d8d4b89742e1a2cec5a1120311f1 489 Gene3D G3DSA:3.50.50.60 146 255 8.8E-9 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01790 eee2d8d4b89742e1a2cec5a1120311f1 489 Gene3D G3DSA:3.50.50.60 1 145 7.4E-16 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01790 eee2d8d4b89742e1a2cec5a1120311f1 489 SUPERFAMILY SSF51905 1 480 2.92E-24 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_01790 eee2d8d4b89742e1a2cec5a1120311f1 489 PIRSF PIRSF038984 121 481 9.9E-21 T 15-10-2018 IPR028348 FAD dependent protein C2I28_01790 eee2d8d4b89742e1a2cec5a1120311f1 489 PIRSF PIRSF038984 1 115 6.6E-7 T 15-10-2018 IPR028348 FAD dependent protein C2I28_18785 fb9c8474846b0c1bfe63e26ad14251f1 203 Pfam PF01810 LysE type translocator 15 197 2.3E-24 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_00600 bfadf1d19135fbc7465fbd1cb2edf4cd 536 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 374 522 6.8E-25 T 15-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I28_00600 bfadf1d19135fbc7465fbd1cb2edf4cd 536 Pfam PF01943 Polysaccharide biosynthesis protein 5 319 4.6E-38 T 15-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I28_00600 bfadf1d19135fbc7465fbd1cb2edf4cd 536 PIRSF PIRSF038958 1 535 6.2E-116 T 15-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I28_14040 3d030d384f597919c183325beabca3a0 148 Pfam PF10710 Protein of unknown function (DUF2512) 1 138 3.0E-39 T 15-10-2018 IPR019649 Protein of unknown function DUF2512 C2I28_02175 376544c11e46df796a459e189dc6bbb1 324 SUPERFAMILY SSF47413 2 75 1.75E-8 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_02175 376544c11e46df796a459e189dc6bbb1 324 SMART SM00530 7 68 2.6E-4 T 15-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 C2I28_02175 376544c11e46df796a459e189dc6bbb1 324 Pfam PF13413 Helix-turn-helix domain 7 67 2.3E-21 T 15-10-2018 C2I28_02175 376544c11e46df796a459e189dc6bbb1 324 Pfam PF13464 Domain of unknown function (DUF4115) 244 313 4.3E-14 T 15-10-2018 IPR025194 Domain of unknown function DUF4115 C2I28_02175 376544c11e46df796a459e189dc6bbb1 324 Gene3D G3DSA:1.10.260.40 1 102 5.3E-31 T 15-10-2018 C2I28_19850 c235aafad67232ab782ae2532733a5fa 260 Gene3D G3DSA:1.10.12.10 204 259 1.9E-19 T 15-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal C2I28_19850 c235aafad67232ab782ae2532733a5fa 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 259 4.7E-61 T 15-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 C2I28_19850 c235aafad67232ab782ae2532733a5fa 260 SUPERFAMILY SSF52096 1 259 8.75E-81 T 15-10-2018 IPR029045 ClpP/crotonase-like domain superfamily C2I28_19850 c235aafad67232ab782ae2532733a5fa 260 Gene3D G3DSA:3.90.226.10 2 199 2.7E-65 T 15-10-2018 C2I28_18020 abee264b7d5014f626638636af9daf5e 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 104 217 3.2E-27 T 15-10-2018 IPR002898 MotA/TolQ/ExbB proton channel C2I28_18020 abee264b7d5014f626638636af9daf5e 264 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 15-10-2018 IPR000540 Flagellar motor protein MotA, conserved site C2I28_14715 c58afb9e6c741ab7ddcff20a51d8acea 148 SUPERFAMILY SSF52833 2 141 3.64E-33 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_14715 c58afb9e6c741ab7ddcff20a51d8acea 148 Gene3D G3DSA:3.40.30.10 1 148 1.9E-39 T 15-10-2018 C2I28_14715 c58afb9e6c741ab7ddcff20a51d8acea 148 Pfam PF00578 AhpC/TSA family 5 125 4.6E-13 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_18050 090b337c6e474ff20dc84e1e62c4531b 468 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 458 6.0E-185 T 15-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 C2I28_18050 090b337c6e474ff20dc84e1e62c4531b 468 Pfam PF03553 Na+/H+ antiporter family 184 451 1.5E-53 T 15-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I28_26025 89be232caf749a0c4195de91f4ec6f50 300 Gene3D G3DSA:1.20.1530.20 153 300 5.0E-6 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_26025 89be232caf749a0c4195de91f4ec6f50 300 Pfam PF03547 Membrane transport protein 159 295 2.1E-15 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_23405 f17ce6e5aa5b202d6e39bfddf3ecb7a7 274 SUPERFAMILY SSF52091 166 255 6.87E-10 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_23405 f17ce6e5aa5b202d6e39bfddf3ecb7a7 274 Gene3D G3DSA:3.30.750.24 157 272 1.8E-12 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_21200 9af4c76994556630134ddd74a1ed089d 215 Pfam PF02570 Precorrin-8X methylmutase 16 208 1.5E-76 T 15-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 C2I28_21200 9af4c76994556630134ddd74a1ed089d 215 SUPERFAMILY SSF63965 10 211 4.58E-71 T 15-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 C2I28_21200 9af4c76994556630134ddd74a1ed089d 215 Gene3D G3DSA:3.40.50.10230 5 215 2.4E-82 T 15-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 C2I28_20390 a848a3cd423e6c1b5d8311f24b861768 166 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 152 4.6E-28 T 15-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 C2I28_20390 a848a3cd423e6c1b5d8311f24b861768 166 SUPERFAMILY SSF56300 1 163 7.12E-34 T 15-10-2018 C2I28_20390 a848a3cd423e6c1b5d8311f24b861768 166 Gene3D G3DSA:3.60.21.10 1 160 1.7E-42 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_20390 a848a3cd423e6c1b5d8311f24b861768 166 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 6.6E-30 T 15-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 C2I28_01090 db01a7579e2660fb2127f8f0f6184f1e 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 25 3.4E-9 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_01090 db01a7579e2660fb2127f8f0f6184f1e 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 5 27 1.4E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_08150 3e05cec2d1f7f33db0934ba9215eb92a 74 Pfam PF10704 Protein of unknown function (DUF2508) 1 69 9.6E-26 T 15-10-2018 IPR019644 Protein of unknown function DUF2508 C2I28_15040 cd2c6820be53bb0cbd77be2612872f6a 235 SUPERFAMILY SSF158499 130 195 4.84E-19 T 15-10-2018 IPR034829 DnaD-like domain superfamily C2I28_15040 cd2c6820be53bb0cbd77be2612872f6a 235 Gene3D G3DSA:1.10.10.10 1 116 7.7E-38 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_15040 cd2c6820be53bb0cbd77be2612872f6a 235 SUPERFAMILY SSF46785 16 118 5.37E-8 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_15040 cd2c6820be53bb0cbd77be2612872f6a 235 Gene3D G3DSA:1.10.10.630 125 201 1.8E-31 T 15-10-2018 IPR034829 DnaD-like domain superfamily C2I28_15040 cd2c6820be53bb0cbd77be2612872f6a 235 Pfam PF07261 Replication initiation and membrane attachment 130 202 1.9E-25 T 15-10-2018 IPR006343 DnaD domain C2I28_15040 cd2c6820be53bb0cbd77be2612872f6a 235 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 200 5.0E-25 T 15-10-2018 IPR006343 DnaD domain C2I28_26870 8b2fcbca95b767239b76aeb2c3ebda29 335 Pfam PF11553 Protein of unknown function (DUF3231) 170 332 1.4E-51 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_26870 8b2fcbca95b767239b76aeb2c3ebda29 335 Pfam PF11553 Protein of unknown function (DUF3231) 3 161 9.5E-44 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_26870 8b2fcbca95b767239b76aeb2c3ebda29 335 Gene3D G3DSA:1.20.1260.10 1 148 4.2E-11 T 15-10-2018 IPR012347 Ferritin-like C2I28_21220 49c76df0f65c8f386e650e05557e74e2 126 SUPERFAMILY SSF52833 10 105 7.16E-25 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_21220 49c76df0f65c8f386e650e05557e74e2 126 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 10 86 1.0E-10 T 15-10-2018 C2I28_21220 49c76df0f65c8f386e650e05557e74e2 126 Gene3D G3DSA:3.40.30.10 9 107 8.8E-26 T 15-10-2018 C2I28_19715 7f1b06436c54fdbf3f114df427e6a4ea 223 Gene3D G3DSA:3.40.109.10 1 223 7.5E-63 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_19715 7f1b06436c54fdbf3f114df427e6a4ea 223 Pfam PF00881 Nitroreductase family 16 201 8.8E-26 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_19715 7f1b06436c54fdbf3f114df427e6a4ea 223 SUPERFAMILY SSF55469 9 222 2.22E-56 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_21375 15d528e1212aebff9b0cf65533a8e465 477 Pfam PF02447 GntP family permease 52 467 5.9E-8 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_23460 01e505e2d3269d45ab70248e7f708b65 89 Pfam PF04226 Transglycosylase associated protein 33 78 8.5E-12 T 15-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 C2I28_00395 f72e46eb0bc85803ada3ae90fcc91be5 182 Pfam PF14278 Transcriptional regulator C-terminal region 89 159 1.3E-12 T 15-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type C2I28_00395 f72e46eb0bc85803ada3ae90fcc91be5 182 Gene3D G3DSA:1.10.357.10 4 174 8.3E-45 T 15-10-2018 C2I28_00395 f72e46eb0bc85803ada3ae90fcc91be5 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 4.9E-5 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_00395 f72e46eb0bc85803ada3ae90fcc91be5 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 4.9E-5 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_00395 f72e46eb0bc85803ada3ae90fcc91be5 182 SUPERFAMILY SSF46689 5 72 2.05E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_00395 f72e46eb0bc85803ada3ae90fcc91be5 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 59 9.6E-9 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_22200 a641751dab07f4b47620a6b6cb693547 61 Pfam PF13314 Domain of unknown function (DUF4083) 3 55 2.3E-9 T 15-10-2018 IPR025143 Protein of unknown function DUF4083 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 Pfam PF02153 Prephenate dehydrogenase 17 275 3.5E-87 T 15-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 SUPERFAMILY SSF55021 290 360 9.43E-9 T 15-10-2018 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 SUPERFAMILY SSF48179 175 284 8.84E-35 T 15-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 Gene3D G3DSA:3.30.70.260 297 362 1.9E-5 T 15-10-2018 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 Gene3D G3DSA:1.10.3660.10 182 296 2.9E-37 T 15-10-2018 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 Gene3D G3DSA:3.40.50.720 1 181 2.2E-58 T 15-10-2018 C2I28_03160 ffd84c1fd4626696201970f685d78738 366 SUPERFAMILY SSF51735 5 171 2.43E-46 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 PRINTS PR00162 Rieske 2Fe-2S subunit signature 118 130 4.9E-6 T 15-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 PRINTS PR00162 Rieske 2Fe-2S subunit signature 94 105 4.9E-6 T 15-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 PRINTS PR00162 Rieske 2Fe-2S subunit signature 130 142 4.9E-6 T 15-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 SUPERFAMILY SSF50022 3 157 1.96E-30 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 Pfam PF00355 Rieske [2Fe-2S] domain 48 146 6.3E-14 T 15-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 Pfam PF08802 Cytochrome B6-F complex Fe-S subunit 6 35 1.8E-6 T 15-10-2018 IPR014909 Cytochrome b6-f complex Fe-S subunit GO:0009496|GO:0042651|GO:0051537|GO:0055114 KEGG: 00195+1.10.9.1|MetaCyc: PWY-101 C2I28_03130 289e0f9604818a4dc3dc42220b19bd32 166 Gene3D G3DSA:2.102.10.10 37 163 2.3E-23 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_05360 22c6b82f30f5ef727524f2760ea14116 198 SUPERFAMILY SSF52540 1 193 4.23E-41 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05360 22c6b82f30f5ef727524f2760ea14116 198 Gene3D G3DSA:3.40.50.300 1 197 2.7E-77 T 15-10-2018 C2I28_05360 22c6b82f30f5ef727524f2760ea14116 198 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 195 28.318 T 15-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 C2I28_05360 22c6b82f30f5ef727524f2760ea14116 198 Pfam PF01121 Dephospho-CoA kinase 3 182 1.1E-61 T 15-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 C2I28_05360 22c6b82f30f5ef727524f2760ea14116 198 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 1.8E-65 T 15-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 C2I28_19235 886ef0f9e604b66ec46649657f834aa0 407 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 227 392 1.1E-38 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_19235 886ef0f9e604b66ec46649657f834aa0 407 Gene3D G3DSA:3.30.300.210 244 396 6.6E-38 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_19235 886ef0f9e604b66ec46649657f834aa0 407 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 8 394 1.6E-97 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_03940 90e04c93a6fe4c7e87d31f1cf90b36b4 318 Pfam PF07136 Protein of unknown function (DUF1385) 56 303 2.9E-79 T 15-10-2018 IPR010787 Protein of unknown function DUF1385 C2I28_03940 90e04c93a6fe4c7e87d31f1cf90b36b4 318 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 56 300 4.0E-102 T 15-10-2018 IPR010787 Protein of unknown function DUF1385 C2I28_00415 a6124127e72bef08ce8a336e162aa5d8 50 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 18 42 4.6E-8 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_00415 a6124127e72bef08ce8a336e162aa5d8 50 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 21 44 1.4E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_20965 c190ce7cfbaba1158f7af99d1f58fda4 334 Pfam PF13478 XdhC Rossmann domain 188 322 9.2E-31 T 15-10-2018 IPR027051 XdhC Rossmann domain C2I28_20965 c190ce7cfbaba1158f7af99d1f58fda4 334 Pfam PF02625 XdhC and CoxI family 15 74 1.3E-12 T 15-10-2018 IPR003777 XdhC- CoxI C2I28_20965 c190ce7cfbaba1158f7af99d1f58fda4 334 Gene3D G3DSA:3.40.50.720 187 333 1.5E-48 T 15-10-2018 C2I28_13320 1593dfbfce0684e2b27334ce368431fc 60 Pfam PF13119 Domain of unknown function (DUF3973) 1 39 1.3E-28 T 15-10-2018 IPR025003 Domain of unknown function DUF3973 C2I28_04735 128e736aa0f819ce5424c3d3979e5c22 212 Pfam PF04239 Protein of unknown function (DUF421) 83 188 1.8E-35 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_04735 128e736aa0f819ce5424c3d3979e5c22 212 Gene3D G3DSA:3.30.240.20 153 210 2.2E-11 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_04735 128e736aa0f819ce5424c3d3979e5c22 212 Gene3D G3DSA:3.30.240.20 75 147 5.1E-25 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_19900 8ff9f597fc29fd1c778391b40a95060a 109 Pfam PF12986 Domain of unknown function (DUF3870) 8 100 5.3E-31 T 15-10-2018 IPR024617 Domain of unknown function DUF3870 C2I28_14920 034eb43a82835e59da0675e9eb8e0109 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 3 110 5.6E-48 T 15-10-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 C2I28_14920 034eb43a82835e59da0675e9eb8e0109 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 30 101 5.6E-15 T 15-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 C2I28_14775 01ef780be086502d6399827d594e71b7 325 SUPERFAMILY SSF52518 3 192 4.24E-66 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_14775 01ef780be086502d6399827d594e71b7 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.3E-40 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_14775 01ef780be086502d6399827d594e71b7 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 8.2E-42 T 15-10-2018 IPR033248 Transketolase, C-terminal domain C2I28_14775 01ef780be086502d6399827d594e71b7 325 Gene3D G3DSA:3.40.50.920 193 325 5.6E-48 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_14775 01ef780be086502d6399827d594e71b7 325 SMART SM00861 4 179 4.9E-63 T 15-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain C2I28_14775 01ef780be086502d6399827d594e71b7 325 SUPERFAMILY SSF52922 189 325 4.32E-43 T 15-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 C2I28_14775 01ef780be086502d6399827d594e71b7 325 Gene3D G3DSA:3.40.50.970 1 192 3.1E-79 T 15-10-2018 C2I28_05785 080c2ecac3889e3938a74cb00cb005b2 59 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 58 9.0E-15 T 15-10-2018 IPR020296 Sporulation protein Cse60 C2I28_05785 080c2ecac3889e3938a74cb00cb005b2 59 Pfam PF10957 Sporulation protein Cse60 1 59 1.9E-27 T 15-10-2018 IPR020296 Sporulation protein Cse60 C2I28_09925 caa730fbd167bbf9b8994564d22de805 75 Hamap MF_00829 UPF0435 protein . 6 73 20.544 T 15-10-2018 IPR009507 Protein of unknown function UPF0435 C2I28_09925 caa730fbd167bbf9b8994564d22de805 75 Pfam PF06569 Protein of unknown function (DUF1128) 3 73 7.9E-34 T 15-10-2018 IPR009507 Protein of unknown function UPF0435 C2I28_22175 92df85d2e1e5716cb7ec8cc9f417b668 320 SUPERFAMILY SSF161098 81 308 1.44E-57 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_22175 92df85d2e1e5716cb7ec8cc9f417b668 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 308 6.3E-24 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_22175 92df85d2e1e5716cb7ec8cc9f417b668 320 Gene3D G3DSA:1.10.3720.10 77 319 2.2E-67 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_00420 5f7c3f16da96e309c4086ccab5a9be00 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 29 8.6E-12 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_00420 5f7c3f16da96e309c4086ccab5a9be00 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 27 7.6E-10 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_06835 96a886c4203fac1eac15e146c7e4cd5a 342 Gene3D G3DSA:3.40.50.1360 90 340 3.1E-82 T 15-10-2018 C2I28_06835 96a886c4203fac1eac15e146c7e4cd5a 342 Pfam PF04198 Putative sugar-binding domain 90 338 1.1E-69 T 15-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 C2I28_06835 96a886c4203fac1eac15e146c7e4cd5a 342 SUPERFAMILY SSF46785 19 84 8.71E-12 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_06835 96a886c4203fac1eac15e146c7e4cd5a 342 SUPERFAMILY SSF100950 91 338 3.82E-68 T 15-10-2018 IPR037171 NagB/RpiA transferase-like C2I28_06835 96a886c4203fac1eac15e146c7e4cd5a 342 Gene3D G3DSA:1.10.10.10 18 89 1.5E-16 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04500 45e380dee47ffcc332ab44ef5c6a1fb6 179 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 81 1.0E-14 T 15-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I28_04500 45e380dee47ffcc332ab44ef5c6a1fb6 179 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 23 174 4.5E-38 T 15-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 C2I28_04500 45e380dee47ffcc332ab44ef5c6a1fb6 179 Gene3D G3DSA:1.20.120.1760 7 178 5.9E-12 T 15-10-2018 C2I28_04500 45e380dee47ffcc332ab44ef5c6a1fb6 179 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 15-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 C2I28_04775 afe2a219fea877a8c97eb1f915fa7869 178 Pfam PF08977 Bypass of Forespore C, N terminal 33 81 4.2E-12 T 15-10-2018 IPR015071 Bypass-of-forespore C, N-terminal C2I28_04775 afe2a219fea877a8c97eb1f915fa7869 178 Gene3D G3DSA:3.10.20.420 32 84 5.1E-8 T 15-10-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily C2I28_04775 afe2a219fea877a8c97eb1f915fa7869 178 Pfam PF08955 BofC C-terminal domain 85 158 1.1E-26 T 15-10-2018 IPR015050 Bypass of forespore C, C-terminal C2I28_04775 afe2a219fea877a8c97eb1f915fa7869 178 Gene3D G3DSA:3.30.70.1740 85 162 1.7E-30 T 15-10-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily C2I28_07285 1b4f8112a0e26ed1b8bd9aa4e3290a01 276 SUPERFAMILY SSF51261 110 219 1.41E-28 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_07285 1b4f8112a0e26ed1b8bd9aa4e3290a01 276 Gene3D G3DSA:2.70.70.10 75 232 1.7E-48 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_07285 1b4f8112a0e26ed1b8bd9aa4e3290a01 276 Pfam PF01551 Peptidase family M23 118 216 4.7E-24 T 15-10-2018 IPR016047 Peptidase M23 C2I28_24765 3aaadb0cd62f24b40d00beb27401dfe7 272 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 7 248 1.7E-47 T 15-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 C2I28_24765 3aaadb0cd62f24b40d00beb27401dfe7 272 SUPERFAMILY SSF89550 6 271 3.92E-51 T 15-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 C2I28_24765 3aaadb0cd62f24b40d00beb27401dfe7 272 Gene3D G3DSA:3.20.20.140 7 272 9.1E-72 T 15-10-2018 C2I28_24765 3aaadb0cd62f24b40d00beb27401dfe7 272 Pfam PF02811 PHP domain 8 202 6.6E-13 T 15-10-2018 IPR004013 PHP domain GO:0003824 C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 SUPERFAMILY SSF47090 278 345 1.2E-20 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 Pfam PF03734 L,D-transpeptidase catalytic domain 37 160 7.2E-25 T 15-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 Gene3D G3DSA:1.10.101.10 275 348 3.2E-26 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 Gene3D G3DSA:1.10.101.10 186 267 7.7E-28 T 15-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 SUPERFAMILY SSF141523 35 160 5.49E-33 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 Pfam PF01471 Putative peptidoglycan binding domain 200 255 8.4E-20 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 Pfam PF01471 Putative peptidoglycan binding domain 290 345 3.4E-19 T 15-10-2018 IPR002477 Peptidoglycan binding-like C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 SUPERFAMILY SSF47090 188 256 1.26E-22 T 15-10-2018 IPR036365 PGBD-like superfamily C2I28_13265 fd0adf8d514abdd9d098ff564a944cab 348 Gene3D G3DSA:2.40.440.10 30 162 4.4E-38 T 15-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like C2I28_02065 49c1861d2c5e8b4152e2e643480e22d6 135 SMART SM00422 12 80 1.3E-27 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_02065 49c1861d2c5e8b4152e2e643480e22d6 135 Pfam PF13411 MerR HTH family regulatory protein 13 78 2.5E-17 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_02065 49c1861d2c5e8b4152e2e643480e22d6 135 Gene3D G3DSA:1.10.1660.10 1 82 4.0E-24 T 15-10-2018 C2I28_02065 49c1861d2c5e8b4152e2e643480e22d6 135 SUPERFAMILY SSF46955 12 100 1.24E-18 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_03805 86ed10c6b6e989ba77f88b890c6e77e0 443 Gene3D G3DSA:1.20.1250.20 14 441 4.5E-118 T 15-10-2018 C2I28_03805 86ed10c6b6e989ba77f88b890c6e77e0 443 SUPERFAMILY SSF103473 10 436 8.24E-41 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_03805 86ed10c6b6e989ba77f88b890c6e77e0 443 Pfam PF00854 POT family 230 409 4.3E-36 T 15-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I28_03805 86ed10c6b6e989ba77f88b890c6e77e0 443 Pfam PF00854 POT family 96 199 4.7E-24 T 15-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 C2I28_03805 86ed10c6b6e989ba77f88b890c6e77e0 443 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 213 1.1E-56 T 15-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I28_03805 86ed10c6b6e989ba77f88b890c6e77e0 443 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 226 442 4.3E-48 T 15-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 C2I28_00745 55664acf9b66596d3c90a743bba1c8fc 173 Pfam PF14317 YcxB-like protein 105 166 8.5E-12 T 15-10-2018 IPR025588 YcxB-like protein C2I28_22510 2c1056e228ed6488eaa5744c20ce8a3e 267 Hamap MF_02077 Lipid II flippase Amj [amj]. 2 264 25.487 T 15-10-2018 IPR021260 Lipid II flippase Amj C2I28_22510 2c1056e228ed6488eaa5744c20ce8a3e 267 Pfam PF10997 Alternate to MurJ 13 262 7.5E-95 T 15-10-2018 IPR021260 Lipid II flippase Amj C2I28_00575 e0d333e3b7cbfe89b5149222a4952505 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 286 5.2E-34 T 15-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I28_01095 db9af92b046606f0c385b2a197685382 34 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 10 30 4.8E-10 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_01095 db9af92b046606f0c385b2a197685382 34 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 13 30 1.2E-10 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_02900 549fa99c50db01f84ea8748ca070c51b 154 Gene3D G3DSA:3.30.110.150 57 152 3.1E-34 T 15-10-2018 IPR038594 SepF-like superfamily C2I28_02900 549fa99c50db01f84ea8748ca070c51b 154 Pfam PF04472 Cell division protein SepF 65 135 6.9E-30 T 15-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 C2I28_02900 549fa99c50db01f84ea8748ca070c51b 154 Hamap MF_01197 Cell division protein SepF [sepF]. 1 143 20.387 T 15-10-2018 IPR023052 Cell division protein SepF GO:0090529 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 Gene3D G3DSA:1.10.10.10 9 91 1.3E-23 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 4.7E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 4.7E-6 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 Gene3D G3DSA:3.40.640.10 100 464 5.9E-122 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 SUPERFAMILY SSF46785 12 96 2.61E-23 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 83 3.6E-17 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 Pfam PF00155 Aminotransferase class I and II 122 429 4.5E-13 T 15-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 SMART SM00345 24 83 1.4E-16 T 15-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 C2I28_12420 7f14a1c38385a24cc04edbb2988629d0 470 SUPERFAMILY SSF53383 109 469 5.94E-79 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_19550 9a71d3e466984608cd14ecb04263e420 286 Gene3D G3DSA:3.75.10.10 7 286 2.8E-80 T 15-10-2018 C2I28_19550 9a71d3e466984608cd14ecb04263e420 286 SUPERFAMILY SSF55909 11 285 3.03E-76 T 15-10-2018 C2I28_19550 9a71d3e466984608cd14ecb04263e420 286 Pfam PF02274 Amidinotransferase 27 285 1.4E-47 T 15-10-2018 C2I28_26580 1cbb1c1c0899275f3bf05bfac519df50 396 Pfam PF01098 Cell cycle protein 15 378 5.3E-108 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_14680 63d74f7655bd62cdb2c9377861a9e353 151 Gene3D G3DSA:3.10.580.10 1 143 5.9E-52 T 15-10-2018 C2I28_14680 63d74f7655bd62cdb2c9377861a9e353 151 SUPERFAMILY SSF54631 15 139 6.71E-27 T 15-10-2018 C2I28_14680 63d74f7655bd62cdb2c9377861a9e353 151 Pfam PF00571 CBS domain 86 138 1.2E-5 T 15-10-2018 IPR000644 CBS domain C2I28_12545 18aa6aa5a388d25b6a6fca1cec2064e1 314 SUPERFAMILY SSF53807 40 305 1.53E-61 T 15-10-2018 C2I28_12545 18aa6aa5a388d25b6a6fca1cec2064e1 314 Gene3D G3DSA:3.40.50.1980 34 144 1.6E-30 T 15-10-2018 C2I28_12545 18aa6aa5a388d25b6a6fca1cec2064e1 314 Gene3D G3DSA:3.40.50.1980 146 312 1.5E-42 T 15-10-2018 C2I28_12545 18aa6aa5a388d25b6a6fca1cec2064e1 314 Pfam PF01497 Periplasmic binding protein 58 286 5.7E-33 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_04580 4fdc966c169a88e213013faed3e09df3 218 Gene3D G3DSA:3.40.50.150 1 218 2.1E-62 T 15-10-2018 C2I28_04580 4fdc966c169a88e213013faed3e09df3 218 Pfam PF01596 O-methyltransferase 15 212 9.9E-30 T 15-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 C2I28_04580 4fdc966c169a88e213013faed3e09df3 218 SUPERFAMILY SSF53335 8 215 1.7E-39 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_15240 bd5bcc3cd4c1dd0bb3ce6e04eb982a88 317 SUPERFAMILY SSF161098 77 307 3.14E-57 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15240 bd5bcc3cd4c1dd0bb3ce6e04eb982a88 317 Gene3D G3DSA:1.10.3720.10 73 316 5.5E-68 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_15240 bd5bcc3cd4c1dd0bb3ce6e04eb982a88 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 309 2.3E-16 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_15425 1e9aaad6a3c3fe0fd44695ccf02bda8e 259 SUPERFAMILY SSF56601 19 251 3.82E-40 T 15-10-2018 IPR012338 Beta-lactamase/transpeptidase-like C2I28_15425 1e9aaad6a3c3fe0fd44695ccf02bda8e 259 Pfam PF13354 Beta-lactamase enzyme family 31 233 3.1E-51 T 15-10-2018 C2I28_15425 1e9aaad6a3c3fe0fd44695ccf02bda8e 259 Gene3D G3DSA:3.40.710.10 1 258 7.1E-58 T 15-10-2018 C2I28_23175 7fab8accbcbf42cff6d22b5aab936df3 527 Pfam PF07905 Purine catabolism regulatory protein-like family 6 121 6.0E-30 T 15-10-2018 IPR012914 Purine catabolism PurC-like domain C2I28_23175 7fab8accbcbf42cff6d22b5aab936df3 527 Gene3D G3DSA:1.10.10.2840 395 524 7.2E-19 T 15-10-2018 C2I28_23175 7fab8accbcbf42cff6d22b5aab936df3 527 Pfam PF13556 PucR C-terminal helix-turn-helix domain 462 520 9.0E-21 T 15-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain C2I28_10865 f559a677c93ea5cbd4b980050d666329 244 Pfam PF00005 ABC transporter 17 169 1.6E-33 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_10865 f559a677c93ea5cbd4b980050d666329 244 Gene3D G3DSA:3.40.50.300 1 243 4.2E-76 T 15-10-2018 C2I28_10865 f559a677c93ea5cbd4b980050d666329 244 SUPERFAMILY SSF52540 1 239 7.91E-80 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_10865 f559a677c93ea5cbd4b980050d666329 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_10865 f559a677c93ea5cbd4b980050d666329 244 SMART SM00382 26 217 2.6E-15 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_10865 f559a677c93ea5cbd4b980050d666329 244 PIRSF PIRSF039085 1 244 6.0E-117 T 15-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 C2I28_04985 42500bfb04ab7cb3456297d53f50103e 161 ProDom PD104119 YSXD OB2071 ORFY 1 146 3.0E-13 T 15-10-2018 C2I28_04080 c6bd9e331d4c6620995620e7a7328ffe 265 Pfam PF01940 Integral membrane protein DUF92 11 252 1.4E-63 T 15-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 C2I28_00365 35c134782aa7b810a2811644ed05e92b 169 Gene3D G3DSA:2.40.100.20 51 167 3.8E-17 T 15-10-2018 C2I28_00365 35c134782aa7b810a2811644ed05e92b 169 Pfam PF04126 Cyclophilin-like 52 157 6.1E-5 T 15-10-2018 IPR025658 Cyclophilin TM1367-like domain C2I28_00365 35c134782aa7b810a2811644ed05e92b 169 SUPERFAMILY SSF50891 52 166 2.05E-25 T 15-10-2018 IPR029000 Cyclophilin-like domain superfamily C2I28_12130 3923570e44ba3153e8341f64e9aa164a 65 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 63 3.4E-34 T 15-10-2018 IPR019240 Protein of unknown function DUF2196 C2I28_12130 3923570e44ba3153e8341f64e9aa164a 65 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 1.9E-32 T 15-10-2018 IPR019240 Protein of unknown function DUF2196 C2I28_22900 720a231f5dbf992a9875988f366fb0ce 486 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 4 484 3.6E-114 T 15-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 C2I28_22900 720a231f5dbf992a9875988f366fb0ce 486 Gene3D G3DSA:3.50.50.60 1 99 2.9E-26 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22900 720a231f5dbf992a9875988f366fb0ce 486 Gene3D G3DSA:3.50.50.60 197 326 5.4E-19 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22900 720a231f5dbf992a9875988f366fb0ce 486 SUPERFAMILY SSF51905 1 483 1.88E-65 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22900 720a231f5dbf992a9875988f366fb0ce 486 Pfam PF01593 Flavin containing amine oxidoreductase 11 483 2.2E-26 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_17195 ab2524460a2ecbe45f8089ee93ba4c56 350 SUPERFAMILY SSF74650 10 345 1.44E-114 T 15-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 C2I28_17195 ab2524460a2ecbe45f8089ee93ba4c56 350 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 175 184 - T 15-10-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 C2I28_17195 ab2524460a2ecbe45f8089ee93ba4c56 350 Pfam PF01263 Aldose 1-epimerase 18 343 3.8E-96 T 15-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 C2I28_17195 ab2524460a2ecbe45f8089ee93ba4c56 350 Gene3D G3DSA:2.70.98.10 8 349 4.6E-124 T 15-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 C2I28_17195 ab2524460a2ecbe45f8089ee93ba4c56 350 PIRSF PIRSF005096 1 348 1.8E-132 T 15-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 C2I28_20085 ff2b32077bfaa8468e254af4b55652de 289 SUPERFAMILY SSF55729 156 284 3.12E-18 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_20085 ff2b32077bfaa8468e254af4b55652de 289 Gene3D G3DSA:3.40.630.30 147 288 5.5E-20 T 15-10-2018 C2I28_20085 ff2b32077bfaa8468e254af4b55652de 289 Pfam PF00583 Acetyltransferase (GNAT) family 199 276 1.2E-10 T 15-10-2018 IPR000182 GNAT domain C2I28_14115 0c3825889225ba1c4a11767f7204705a 316 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 107 159 1.2E-8 T 15-10-2018 IPR039506 SpoOB, alpha-helical domain C2I28_14115 0c3825889225ba1c4a11767f7204705a 316 Gene3D G3DSA:3.30.565.10 159 307 3.7E-18 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14115 0c3825889225ba1c4a11767f7204705a 316 SUPERFAMILY SSF55874 168 296 1.42E-14 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14115 0c3825889225ba1c4a11767f7204705a 316 Pfam PF14501 GHKL domain 203 305 2.5E-12 T 15-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain C2I28_14115 0c3825889225ba1c4a11767f7204705a 316 SMART SM00387 204 310 4.4E-5 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_14885 dc56c1ae89b98e59f97e585275914885 396 Pfam PF01098 Cell cycle protein 13 370 2.7E-107 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_14885 dc56c1ae89b98e59f97e585275914885 396 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 329 353 - T 15-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_11725 6761a75b1db3b69fc4e6002ca9ab8406 191 Pfam PF13508 Acetyltransferase (GNAT) domain 52 110 1.8E-7 T 15-10-2018 IPR000182 GNAT domain C2I28_11725 6761a75b1db3b69fc4e6002ca9ab8406 191 Gene3D G3DSA:3.40.630.30 1 136 2.3E-23 T 15-10-2018 C2I28_11725 6761a75b1db3b69fc4e6002ca9ab8406 191 SUPERFAMILY SSF55729 47 116 2.36E-9 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_00780 9a4a5c9a26076dbee71fd396e0642e69 173 Gene3D G3DSA:1.20.1260.10 1 172 1.2E-44 T 15-10-2018 IPR012347 Ferritin-like C2I28_00780 9a4a5c9a26076dbee71fd396e0642e69 173 SUPERFAMILY SSF47240 1 160 3.29E-47 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_00780 9a4a5c9a26076dbee71fd396e0642e69 173 Pfam PF00210 Ferritin-like domain 7 141 1.4E-35 T 15-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I28_16575 07ec4523a6bd7d831f2eb37e603d8f7c 476 SUPERFAMILY SSF50952 49 263 4.45E-10 T 15-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 C2I28_16575 07ec4523a6bd7d831f2eb37e603d8f7c 476 Gene3D G3DSA:2.120.10.30 2 418 3.5E-24 T 15-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like C2I28_16575 07ec4523a6bd7d831f2eb37e603d8f7c 476 Pfam PF07995 Glucose / Sorbosone dehydrogenase 46 278 2.6E-9 T 15-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase C2I28_02130 51a3cfafa90d7877c323110d4f5cc074 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 2.6E-21 T 15-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal C2I28_02130 51a3cfafa90d7877c323110d4f5cc074 288 SUPERFAMILY SSF52518 12 286 6.49E-75 T 15-10-2018 IPR029061 Thiamin diphosphate-binding fold C2I28_02130 51a3cfafa90d7877c323110d4f5cc074 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 271 2.6E-94 T 15-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate C2I28_02130 51a3cfafa90d7877c323110d4f5cc074 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 5.3E-32 T 15-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 C2I28_02130 51a3cfafa90d7877c323110d4f5cc074 288 Gene3D G3DSA:3.40.50.970 67 214 3.7E-28 T 15-10-2018 C2I28_20810 e5a8ad601308563e76476f7360f91b24 163 Pfam PF13420 Acetyltransferase (GNAT) domain 3 156 1.4E-22 T 15-10-2018 C2I28_20810 e5a8ad601308563e76476f7360f91b24 163 Gene3D G3DSA:3.40.630.30 1 163 2.9E-50 T 15-10-2018 C2I28_20810 e5a8ad601308563e76476f7360f91b24 163 SUPERFAMILY SSF55729 2 163 9.78E-35 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_26860 20f35ff206a4ba1e42fe27b2575bbf0f 276 SUPERFAMILY SSF52091 161 269 5.1E-16 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_26860 20f35ff206a4ba1e42fe27b2575bbf0f 276 Pfam PF01740 STAS domain 165 265 2.5E-11 T 15-10-2018 IPR002645 STAS domain C2I28_26860 20f35ff206a4ba1e42fe27b2575bbf0f 276 Gene3D G3DSA:3.30.750.24 156 274 4.3E-33 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_12350 9284f2fe58ed0e663bae5ce754505cd1 352 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 48 303 4.4E-91 T 15-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 C2I28_12350 9284f2fe58ed0e663bae5ce754505cd1 352 Gene3D G3DSA:3.40.190.170 43 346 4.4E-95 T 15-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily C2I28_12350 9284f2fe58ed0e663bae5ce754505cd1 352 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 48 331 2.1E-98 T 15-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 C2I28_12350 9284f2fe58ed0e663bae5ce754505cd1 352 PIRSF PIRSF006470 15 347 2.7E-114 T 15-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 C2I28_14915 a18f5ddabf9abc3b546d756a0a5b493e 206 SUPERFAMILY SSF81452 21 203 3.01E-55 T 15-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14915 a18f5ddabf9abc3b546d756a0a5b493e 206 Pfam PF00510 Cytochrome c oxidase subunit III 28 203 1.1E-17 T 15-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14915 a18f5ddabf9abc3b546d756a0a5b493e 206 Gene3D G3DSA:1.20.120.80 21 205 4.3E-54 T 15-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_15555 4ec7c198f1ab46dd5bcdd1f95a832fec 403 SUPERFAMILY SSF103473 142 395 2.49E-35 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15555 4ec7c198f1ab46dd5bcdd1f95a832fec 403 SUPERFAMILY SSF103473 8 129 1.44E-16 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_15555 4ec7c198f1ab46dd5bcdd1f95a832fec 403 Gene3D G3DSA:1.20.1250.20 14 207 2.4E-30 T 15-10-2018 C2I28_15555 4ec7c198f1ab46dd5bcdd1f95a832fec 403 Gene3D G3DSA:1.20.1250.20 220 402 2.5E-21 T 15-10-2018 C2I28_15555 4ec7c198f1ab46dd5bcdd1f95a832fec 403 Pfam PF07690 Major Facilitator Superfamily 225 394 1.2E-19 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_15555 4ec7c198f1ab46dd5bcdd1f95a832fec 403 Pfam PF07690 Major Facilitator Superfamily 5 146 1.3E-12 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_10290 dba5a1c067a161d1871943720905c4b9 139 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 22 93 6.7E-18 T 15-10-2018 IPR010724 Replication initiator A, N-terminal C2I28_05470 400d028edfd36db372033c2a4a14c53a 98 Pfam PF14007 YtpI-like protein 5 90 2.4E-33 T 15-10-2018 IPR025618 YtpI-like protein C2I28_02535 3168c421b91be6004877bf2755507117 96 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 96 17.982 T 15-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I28_02535 3168c421b91be6004877bf2755507117 96 Pfam PF02049 Flagellar hook-basal body complex protein FliE 12 96 1.8E-27 T 15-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I28_02535 3168c421b91be6004877bf2755507117 96 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 81 94 3.7E-15 T 15-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I28_02535 3168c421b91be6004877bf2755507117 96 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 60 76 3.7E-15 T 15-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I28_02535 3168c421b91be6004877bf2755507117 96 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 26 42 3.7E-15 T 15-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I28_02535 3168c421b91be6004877bf2755507117 96 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 13 96 1.5E-27 T 15-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 C2I28_23240 974f75f52d310cf271da4b60bd2036a9 295 Pfam PF01925 Sulfite exporter TauE/SafE 8 246 2.6E-39 T 15-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 SUPERFAMILY SSF46894 128 227 5.39E-29 T 15-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 Gene3D G3DSA:3.40.50.2300 1 128 4.3E-38 T 15-10-2018 C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 Gene3D G3DSA:1.10.10.10 129 228 9.3E-34 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 SMART SM00448 4 114 7.3E-44 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 SMART SM00862 152 228 1.5E-25 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 6.5E-28 T 15-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 SUPERFAMILY SSF52172 2 130 6.4E-42 T 15-10-2018 IPR011006 CheY-like superfamily C2I28_20490 fdba4aaafb3861fe8fb06bb53fe84b4e 228 Pfam PF00072 Response regulator receiver domain 6 115 3.9E-32 T 15-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 C2I28_21580 6283f3adc78a57d5761de384b1cae79f 192 Gene3D G3DSA:2.60.60.30 19 187 5.7E-69 T 15-10-2018 C2I28_21580 6283f3adc78a57d5761de384b1cae79f 192 Pfam PF02342 TerD domain 1 188 4.1E-83 T 15-10-2018 IPR003325 TerD domain C2I28_05815 143778e73534fc52c6b6d54230457cff 87 Pfam PF10732 Protein of unknown function (DUF2524) 1 83 2.4E-37 T 15-10-2018 IPR019668 Uncharacterised protein family YtzC C2I28_13645 9a8c912499e1c73d8fb479b3f82cc17f 679 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 129 425 1.5E-70 T 15-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 C2I28_13645 9a8c912499e1c73d8fb479b3f82cc17f 679 Pfam PF08486 Stage II sporulation protein 127 207 3.7E-21 T 15-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal C2I28_13645 9a8c912499e1c73d8fb479b3f82cc17f 679 Gene3D G3DSA:2.60.40.10 600 671 2.4E-7 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13645 9a8c912499e1c73d8fb479b3f82cc17f 679 Gene3D G3DSA:2.60.40.10 518 589 2.0E-8 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_13645 9a8c912499e1c73d8fb479b3f82cc17f 679 Gene3D G3DSA:2.60.40.10 436 505 6.0E-7 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_18415 1883e47e0c66a41c93a2874d46f08cd4 50 Pfam PF13076 Fur-regulated basic protein A 12 46 8.0E-17 T 15-10-2018 IPR025072 Fur-regulated basic protein A C2I28_25305 035ce9433a35183aedc3d0aa311fb1c9 175 Gene3D G3DSA:2.60.120.10 53 175 3.3E-43 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_25305 035ce9433a35183aedc3d0aa311fb1c9 175 SUPERFAMILY SSF51182 39 159 1.16E-28 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_25305 035ce9433a35183aedc3d0aa311fb1c9 175 Pfam PF07883 Cupin domain 78 153 3.5E-16 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_23990 7d8959f683d72be38c7b0f4e5409d0cb 204 Gene3D G3DSA:3.40.50.720 1 203 1.9E-53 T 15-10-2018 C2I28_23990 7d8959f683d72be38c7b0f4e5409d0cb 204 SUPERFAMILY SSF51735 1 200 1.37E-38 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_23990 7d8959f683d72be38c7b0f4e5409d0cb 204 Pfam PF13460 NAD(P)H-binding 7 192 1.1E-49 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_05940 8928fcc0d4379fe4c0cde91f0030c927 444 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 434 5.7E-123 T 15-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I28_05940 8928fcc0d4379fe4c0cde91f0030c927 444 PIRSF PIRSF006446 1 444 6.1E-111 T 15-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 C2I28_22370 3ffa3f8faf3cf88e07e4fe803ac90ef3 137 PIRSF PIRSF030042 1 135 2.2E-50 T 15-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 C2I28_22370 3ffa3f8faf3cf88e07e4fe803ac90ef3 137 Pfam PF14340 Domain of unknown function (DUF4395) 3 126 3.3E-23 T 15-10-2018 IPR025508 Domain of unknown function DUF4395 C2I28_14485 4b50a925a3394028f7a8e37cc2764d60 124 SUPERFAMILY SSF81442 9 120 5.63E-12 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_14485 4b50a925a3394028f7a8e37cc2764d60 124 Gene3D G3DSA:1.20.210.10 1 120 4.1E-14 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_25080 c7b96f9a846c74200b7fa84bb5cb7c48 217 Pfam PF13346 ABC-2 family transporter protein 3 212 1.8E-32 T 15-10-2018 IPR025699 ABC-2 membrane transporter-like C2I28_12525 0d593bd7a101958038de5dae7af0ba3f 461 SUPERFAMILY SSF51679 1 437 5.36E-124 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12525 0d593bd7a101958038de5dae7af0ba3f 461 PIRSF PIRSF000337 3 446 2.3E-143 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_12525 0d593bd7a101958038de5dae7af0ba3f 461 Gene3D G3DSA:3.20.20.30 1 458 2.3E-144 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_12525 0d593bd7a101958038de5dae7af0ba3f 461 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 7 434 4.5E-169 T 15-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 C2I28_12525 0d593bd7a101958038de5dae7af0ba3f 461 Pfam PF00296 Luciferase-like monooxygenase 29 392 2.1E-56 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_14895 351fe224bf4bfb76695b5b8f62abfa78 300 Pfam PF02628 Cytochrome oxidase assembly protein 8 287 1.3E-35 T 15-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 C2I28_14895 351fe224bf4bfb76695b5b8f62abfa78 300 Hamap MF_01664 Heme A synthase [ctaA]. 1 300 28.748 T 15-10-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 C2I28_06615 099aff567650b8949bfaf08375e57891 256 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 223 243 1.2E-5 T 15-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 C2I28_06615 099aff567650b8949bfaf08375e57891 256 Pfam PF06276 Ferric iron reductase FhuF-like transporter 58 206 1.5E-10 T 15-10-2018 IPR022770 Ferric iron reductase FhuF domain C2I28_22305 f2877c5c3c49fa4677d88dd76a3f748c 293 Gene3D G3DSA:2.70.70.10 132 284 2.3E-27 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_22305 f2877c5c3c49fa4677d88dd76a3f748c 293 Pfam PF01551 Peptidase family M23 170 262 7.3E-18 T 15-10-2018 IPR016047 Peptidase M23 C2I28_22305 f2877c5c3c49fa4677d88dd76a3f748c 293 SUPERFAMILY SSF51261 170 261 3.4E-19 T 15-10-2018 IPR011055 Duplicated hybrid motif C2I28_25895 2f081960226821483188c0cbad109493 1068 Gene3D G3DSA:3.30.1600.10 36 164 1.5E-6 T 15-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily C2I28_25895 2f081960226821483188c0cbad109493 1068 SUPERFAMILY SSF52540 295 404 1.13E-5 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_25895 2f081960226821483188c0cbad109493 1068 SUPERFAMILY SSF52467 18 231 8.41E-14 T 15-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily C2I28_25895 2f081960226821483188c0cbad109493 1068 Gene3D G3DSA:3.40.50.1220 20 158 1.5E-6 T 15-10-2018 C2I28_13325 9f856da21473ccaca01c5db10080b6aa 129 Gene3D G3DSA:3.10.450.40 3 69 1.6E-10 T 15-10-2018 C2I28_13325 9f856da21473ccaca01c5db10080b6aa 129 Pfam PF03413 Peptidase propeptide and YPEB domain 11 66 3.4E-5 T 15-10-2018 IPR025711 PepSY domain C2I28_06780 dcee1cdb06e57b9235c21e06444972f5 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 25 214 2.9E-23 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_06780 dcee1cdb06e57b9235c21e06444972f5 218 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 216 3.7E-72 T 15-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 C2I28_06780 dcee1cdb06e57b9235c21e06444972f5 218 SUPERFAMILY SSF161098 4 216 1.09E-49 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_06780 dcee1cdb06e57b9235c21e06444972f5 218 Gene3D G3DSA:1.10.3720.10 1 218 7.8E-54 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18870 0c8a80a5266c7e76e945fcd6618d4238 359 Pfam PF14897 EpsG family 40 344 5.3E-58 T 15-10-2018 C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 12 291 2.5E-63 T 15-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 SUPERFAMILY SSF48239 38 296 1.76E-43 T 15-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 305 620 1.5E-96 T 15-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 Gene3D G3DSA:1.50.10.20 16 619 5.7E-197 T 15-10-2018 C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 SUPERFAMILY SSF48239 296 622 7.38E-91 T 15-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 Gene3D G3DSA:1.50.10.20 33 303 5.7E-197 T 15-10-2018 C2I28_18715 bf712e2086d3d49acdbd59b9502603f0 625 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 12 621 6.0E-119 T 15-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 C2I28_08555 b9a67e884445dadc8ba0276a9d6a241e 365 Pfam PF01938 TRAM domain 297 349 3.9E-5 T 15-10-2018 IPR002792 TRAM domain C2I28_08555 b9a67e884445dadc8ba0276a9d6a241e 365 SMART SM00670 165 272 4.1E-12 T 15-10-2018 IPR002716 PIN domain C2I28_08555 b9a67e884445dadc8ba0276a9d6a241e 365 Gene3D G3DSA:3.40.50.1010 162 295 1.4E-52 T 15-10-2018 C2I28_08555 b9a67e884445dadc8ba0276a9d6a241e 365 SUPERFAMILY SSF88723 167 293 2.16E-23 T 15-10-2018 IPR029060 PIN-like domain superfamily C2I28_22190 dd59dfba248253827c39146b9d8199d9 161 SUPERFAMILY SSF55729 1 133 2.34E-9 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_22190 dd59dfba248253827c39146b9d8199d9 161 Pfam PF00583 Acetyltransferase (GNAT) family 50 132 3.1E-7 T 15-10-2018 IPR000182 GNAT domain C2I28_22190 dd59dfba248253827c39146b9d8199d9 161 Gene3D G3DSA:3.40.630.30 2 139 1.5E-8 T 15-10-2018 C2I28_24870 9b4e0a4c61eec7fbb9424e559cb22d0c 325 SUPERFAMILY SSF54593 1 309 2.07E-47 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_24870 9b4e0a4c61eec7fbb9424e559cb22d0c 325 Gene3D G3DSA:3.10.180.10 65 223 1.0E-111 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_24870 9b4e0a4c61eec7fbb9424e559cb22d0c 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 1.7E-15 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_24870 9b4e0a4c61eec7fbb9424e559cb22d0c 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 156 279 1.3E-15 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_24870 9b4e0a4c61eec7fbb9424e559cb22d0c 325 Gene3D G3DSA:3.10.180.10 5 318 1.0E-111 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_18580 cb193aab5dc0c826e42060d00d7c620c 322 Pfam PF01261 Xylose isomerase-like TIM barrel 19 236 1.4E-31 T 15-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain C2I28_18580 cb193aab5dc0c826e42060d00d7c620c 322 Pfam PF07582 AP endonuclease family 2 C terminus 268 322 1.4E-22 T 15-10-2018 IPR011418 AP endonuclease, family 2, C-terminal C2I28_18580 cb193aab5dc0c826e42060d00d7c620c 322 SUPERFAMILY SSF51658 1 311 1.01E-51 T 15-10-2018 IPR036237 Xylose isomerase-like superfamily C2I28_18580 cb193aab5dc0c826e42060d00d7c620c 322 Gene3D G3DSA:3.20.20.150 1 315 2.5E-72 T 15-10-2018 C2I28_18140 cfb7363923e909ab3f738d4a206ee79d 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 118 5.1E-19 T 15-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 C2I28_18140 cfb7363923e909ab3f738d4a206ee79d 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 212 8.9E-18 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_18140 cfb7363923e909ab3f738d4a206ee79d 232 Gene3D G3DSA:1.10.3720.10 4 227 8.3E-46 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_18140 cfb7363923e909ab3f738d4a206ee79d 232 SUPERFAMILY SSF161098 15 212 6.02E-38 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_04600 7a87f60114438d2c4ee4516d9eba0828 89 PIRSF PIRSF037258 1 88 3.8E-46 T 15-10-2018 IPR009309 Uncharacterised protein family UPF0297 C2I28_04600 7a87f60114438d2c4ee4516d9eba0828 89 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 7.8E-38 T 15-10-2018 IPR009309 Uncharacterised protein family UPF0297 C2I28_04600 7a87f60114438d2c4ee4516d9eba0828 89 Hamap MF_01507 UPF0297 protein . 1 85 28.254 T 15-10-2018 IPR009309 Uncharacterised protein family UPF0297 C2I28_14350 8f6c5be404caf694b186002d4e3c41b5 255 PIRSF PIRSF031505 1 255 9.8E-97 T 15-10-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative C2I28_14350 8f6c5be404caf694b186002d4e3c41b5 255 Gene3D G3DSA:3.30.428.10 56 130 1.7E-12 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_14350 8f6c5be404caf694b186002d4e3c41b5 255 Pfam PF16285 Domain of unknown function (DUF4931) 8 254 9.2E-111 T 15-10-2018 C2I28_14350 8f6c5be404caf694b186002d4e3c41b5 255 SUPERFAMILY SSF54197 15 130 1.17E-22 T 15-10-2018 IPR036265 HIT-like superfamily C2I28_11935 33bbc9df2ae587583c8a4ae9f1a14fe0 159 Pfam PF00583 Acetyltransferase (GNAT) family 58 145 8.4E-10 T 15-10-2018 IPR000182 GNAT domain C2I28_11935 33bbc9df2ae587583c8a4ae9f1a14fe0 159 SUPERFAMILY SSF55729 2 151 1.08E-21 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_11935 33bbc9df2ae587583c8a4ae9f1a14fe0 159 Gene3D G3DSA:3.40.630.30 4 158 2.5E-28 T 15-10-2018 C2I28_11045 11051808653754bdc8620ed79afe662a 60 Pfam PF14147 Sporulation protein YhaL 4 55 3.2E-27 T 15-10-2018 IPR025428 Sporulation protein YhaL C2I28_03515 9ce669abc57b2583bbc4cb2c5d550dcb 206 Gene3D G3DSA:2.60.480.10 1 95 4.5E-12 T 15-10-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily C2I28_03515 9ce669abc57b2583bbc4cb2c5d550dcb 206 Pfam PF12164 Stage V sporulation protein AA 3 88 6.9E-20 T 15-10-2018 IPR021997 Stage V sporulation protein AA C2I28_19230 5ebd4e0f024dce697f7c5581d65c964e 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 363 8.1E-75 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_19230 5ebd4e0f024dce697f7c5581d65c964e 366 Pfam PF03845 Spore germination protein 5 325 2.8E-86 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_26105 f36e02e16f3680fa6dba827bdc9cecdf 871 Pfam PF02687 FtsX-like permease family 777 864 1.5E-9 T 15-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I28_26105 f36e02e16f3680fa6dba827bdc9cecdf 871 Pfam PF02687 FtsX-like permease family 279 374 7.5E-11 T 15-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I28_26105 f36e02e16f3680fa6dba827bdc9cecdf 871 Pfam PF12704 MacB-like periplasmic core domain 478 716 1.6E-7 T 15-10-2018 IPR025857 MacB-like periplasmic core domain C2I28_26105 f36e02e16f3680fa6dba827bdc9cecdf 871 Pfam PF12704 MacB-like periplasmic core domain 19 220 3.6E-9 T 15-10-2018 IPR025857 MacB-like periplasmic core domain C2I28_20310 845a57db169120b87247a74c994eaea9 243 Pfam PF05076 Suppressor of fused protein (SUFU) 65 235 3.4E-42 T 15-10-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 C2I28_20310 845a57db169120b87247a74c994eaea9 243 SUPERFAMILY SSF103359 66 238 1.23E-5 T 15-10-2018 IPR037181 Suppressor of fused, N-terminal Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 C2I28_01725 ffeff2159e3acbde1ba84d4f476d1deb 56 ProDom PD052277 YOZD 1 53 2.0E-17 T 15-10-2018 C2I28_01725 ffeff2159e3acbde1ba84d4f476d1deb 56 Pfam PF14162 YozD-like protein 2 54 2.5E-33 T 15-10-2018 IPR025545 YozD-like protein C2I28_02545 9269513e42a15a302b2520f86478e786 129 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 126 1.8E-31 T 15-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 C2I28_02545 9269513e42a15a302b2520f86478e786 129 PIRSF PIRSF002889 2 128 1.4E-32 T 15-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 C2I28_02545 9269513e42a15a302b2520f86478e786 129 Pfam PF00460 Flagella basal body rod protein 9 38 1.3E-6 T 15-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 15-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 Gene3D G3DSA:3.30.70.920 51 138 6.6E-19 T 15-10-2018 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 SMART SM00344 1 107 1.0E-35 T 15-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.4E-14 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.4E-14 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.4E-14 T 15-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 3.5E-15 T 15-10-2018 C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 Gene3D G3DSA:1.10.10.10 1 50 2.1E-18 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 SUPERFAMILY SSF46785 1 60 3.62E-15 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 SUPERFAMILY SSF54909 64 137 6.44E-15 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_11975 805dba9c85d186a491533d748ee8dc41 149 Pfam PF01037 Lrp/AsnC ligand binding domain 74 133 1.0E-11 T 15-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain C2I28_25660 98fc83258fa051d560d114af3c568875 387 Pfam PF13786 Domain of unknown function (DUF4179) 43 132 6.9E-12 T 15-10-2018 IPR025436 Domain of unknown function DUF4179 C2I28_05690 c5ee6a314c12fc03a76bfde910a4d560 270 Hamap MF_01548 UPF0354 protein . 4 268 47.626 T 15-10-2018 IPR010838 Protein of unknown unction DUF1444 C2I28_05690 c5ee6a314c12fc03a76bfde910a4d560 270 Pfam PF07285 Protein of unknown function (DUF1444) 4 267 9.6E-131 T 15-10-2018 IPR010838 Protein of unknown unction DUF1444 C2I28_05690 c5ee6a314c12fc03a76bfde910a4d560 270 PIRSF PIRSF012562 2 268 1.6E-133 T 15-10-2018 IPR010838 Protein of unknown unction DUF1444 C2I28_21590 26004195d094aa094b89ab2bb24ba7f8 198 Pfam PF02342 TerD domain 2 196 1.7E-72 T 15-10-2018 IPR003325 TerD domain C2I28_21590 26004195d094aa094b89ab2bb24ba7f8 198 Gene3D G3DSA:2.60.60.30 19 195 1.9E-61 T 15-10-2018 C2I28_20700 5154b10f9026ad91a7dd8be308a64bc5 440 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 334 354 - T 15-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I28_20700 5154b10f9026ad91a7dd8be308a64bc5 440 Pfam PF00860 Permease family 11 387 4.4E-123 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_20700 5154b10f9026ad91a7dd8be308a64bc5 440 TIGRFAM TIGR03173 pbuX: xanthine permease 13 419 9.5E-165 T 15-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 C2I28_20700 5154b10f9026ad91a7dd8be308a64bc5 440 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 9 416 1.5E-141 T 15-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 C2I28_09135 86af0564915a01160ab5f8cd5bf0ab0d 352 SUPERFAMILY SSF89392 49 222 4.32E-15 T 15-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX C2I28_09135 86af0564915a01160ab5f8cd5bf0ab0d 352 Gene3D G3DSA:2.50.20.10 41 233 3.1E-9 T 15-10-2018 C2I28_20295 1b573951f7baac904e1e0c6b83e22719 226 Pfam PF09951 Protein of unknown function (DUF2185) 132 214 8.7E-24 T 15-10-2018 IPR018689 Domain of unknown function DUF2185 C2I28_20295 1b573951f7baac904e1e0c6b83e22719 226 Pfam PF10077 Uncharacterized protein conserved in bacteria (DUF2314) 51 131 5.4E-8 T 15-10-2018 IPR018756 Domain of unknown function DUF2314 C2I28_02220 61109349bcb18d8411b783156426d2bf 362 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 41 349 1.6E-84 T 15-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 C2I28_02220 61109349bcb18d8411b783156426d2bf 362 Gene3D G3DSA:3.40.50.2300 43 311 6.6E-115 T 15-10-2018 C2I28_02220 61109349bcb18d8411b783156426d2bf 362 SUPERFAMILY SSF53822 53 269 1.88E-13 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_02220 61109349bcb18d8411b783156426d2bf 362 Gene3D G3DSA:3.40.50.2300 149 344 6.6E-115 T 15-10-2018 C2I28_05775 732e5795d1136635a80c969a7545fbd3 547 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 374 519 1.6E-27 T 15-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain C2I28_05775 732e5795d1136635a80c969a7545fbd3 547 PIRSF PIRSF038958 1 538 1.1E-133 T 15-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type C2I28_05775 732e5795d1136635a80c969a7545fbd3 547 Pfam PF01943 Polysaccharide biosynthesis protein 6 320 1.2E-52 T 15-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 C2I28_21205 56850baa1ed2620342299e6802017eb3 255 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 249 2.2E-78 T 15-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 C2I28_21205 56850baa1ed2620342299e6802017eb3 255 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 244 4.1E-62 T 15-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 C2I28_18010 5da19ae0a27e8029514d9f1bfc92337f 219 Gene3D G3DSA:1.10.510.10 21 176 9.1E-8 T 15-10-2018 C2I28_18010 5da19ae0a27e8029514d9f1bfc92337f 219 SUPERFAMILY SSF56112 36 193 1.08E-11 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_06460 379269ffc24b9954639e6349c315b2ba 145 Pfam PF01934 Protein of unknown function DUF86 30 128 1.7E-21 T 15-10-2018 IPR008201 Protein of unknown function DUF86 C2I28_06460 379269ffc24b9954639e6349c315b2ba 145 Gene3D G3DSA:1.20.120.580 1 144 2.7E-55 T 15-10-2018 IPR037038 Bsu32300-like superfamily C2I28_20020 91b28c0f7c51fefd2e297c08454b06b8 152 Pfam PF07486 Cell Wall Hydrolase 53 150 4.7E-27 T 15-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 C2I28_20020 91b28c0f7c51fefd2e297c08454b06b8 152 Gene3D G3DSA:1.10.10.2520 37 116 1.1E-31 T 15-10-2018 C2I28_20020 91b28c0f7c51fefd2e297c08454b06b8 152 Gene3D G3DSA:2.40.10.420 119 152 6.4E-11 T 15-10-2018 C2I28_20650 1d76950948a13d22d28fecbe197c6037 142 Gene3D G3DSA:3.40.630.30 1 141 2.3E-41 T 15-10-2018 C2I28_20650 1d76950948a13d22d28fecbe197c6037 142 SUPERFAMILY SSF55729 2 140 2.62E-35 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_20650 1d76950948a13d22d28fecbe197c6037 142 Pfam PF13673 Acetyltransferase (GNAT) domain 21 139 1.2E-19 T 15-10-2018 IPR000182 GNAT domain C2I28_24405 8ab63807edcdf79723a4cd8c15f5f2e5 88 Pfam PF05120 Gas vesicle protein G 2 77 2.9E-17 T 15-10-2018 IPR007804 Gas vesicle protein GvpG C2I28_19160 1570dc6a3bca63acb13edb31c5df1db4 551 Pfam PF10101 Predicted membrane protein (DUF2339) 77 429 9.7E-26 T 15-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane C2I28_19160 1570dc6a3bca63acb13edb31c5df1db4 551 Pfam PF10101 Predicted membrane protein (DUF2339) 403 546 1.1E-10 T 15-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane C2I28_18280 18b18da9ca6a00fb2b646ae4ef480754 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 3.0E-15 T 15-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I28_18280 18b18da9ca6a00fb2b646ae4ef480754 59 Pfam PF08141 Small acid-soluble spore protein H family 2 58 3.1E-24 T 15-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I28_18280 18b18da9ca6a00fb2b646ae4ef480754 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 2 58 2.1E-23 T 15-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I28_18280 18b18da9ca6a00fb2b646ae4ef480754 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 17.942 T 15-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 C2I28_12065 ede137c87b6bf459b11dc162a1728566 468 Gene3D G3DSA:3.90.1300.10 1 458 3.6E-152 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_12065 ede137c87b6bf459b11dc162a1728566 468 ProSitePatterns PS00571 Amidases signature. 146 177 - T 15-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 C2I28_12065 ede137c87b6bf459b11dc162a1728566 468 SUPERFAMILY SSF75304 1 451 3.79E-142 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_12065 ede137c87b6bf459b11dc162a1728566 468 Pfam PF01425 Amidase 19 441 3.6E-123 T 15-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_22885 7aed21a9636e5a7573c55f6950f0f91f 319 Pfam PF00294 pfkB family carbohydrate kinase 5 303 1.6E-60 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_22885 7aed21a9636e5a7573c55f6950f0f91f 319 Gene3D G3DSA:3.40.1190.20 4 316 2.3E-89 T 15-10-2018 IPR029056 Ribokinase-like C2I28_22885 7aed21a9636e5a7573c55f6950f0f91f 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_22885 7aed21a9636e5a7573c55f6950f0f91f 319 SUPERFAMILY SSF53613 2 311 4.83E-84 T 15-10-2018 IPR029056 Ribokinase-like C2I28_07100 fd410700bdefe745149b69adf294ce4b 570 Gene3D G3DSA:1.20.1730.10 84 553 1.8E-75 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_07100 fd410700bdefe745149b69adf294ce4b 570 Pfam PF00474 Sodium:solute symporter family 99 498 2.9E-36 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_06420 3298cc65d000d1534af9bef9ca1b0512 76 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 12 63 3.0E-22 T 15-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 C2I28_06420 3298cc65d000d1534af9bef9ca1b0512 76 Gene3D G3DSA:3.30.300.130 1 76 3.2E-33 T 15-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I28_06420 3298cc65d000d1534af9bef9ca1b0512 76 Pfam PF01106 NifU-like domain 8 73 4.6E-28 T 15-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 C2I28_06420 3298cc65d000d1534af9bef9ca1b0512 76 SUPERFAMILY SSF117916 2 75 5.56E-27 T 15-10-2018 IPR034904 Fe-S cluster assembly domain superfamily C2I28_17340 fdeb9f72d0b46696307dde2ae2b407db 108 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 7 107 4.1E-11 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_25940 7f79114e0e24d119484ce5adaa5509d8 164 TIGRFAM TIGR03645 glyox_marine: lactoylglutathione lyase family protein 4 164 7.4E-92 T 15-10-2018 IPR019883 Lactoylglutathione lyase C2I28_25940 7f79114e0e24d119484ce5adaa5509d8 164 Gene3D G3DSA:3.10.180.10 4 160 6.2E-26 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_25940 7f79114e0e24d119484ce5adaa5509d8 164 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 150 1.8E-14 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_25940 7f79114e0e24d119484ce5adaa5509d8 164 SUPERFAMILY SSF54593 5 155 4.97E-31 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_10140 8de39fc663b7877d0004cfc781355a9d 263 Pfam PF06182 ABC-2 family transporter protein 31 262 8.7E-19 T 15-10-2018 IPR010390 Protein of unknown function DUF990 C2I28_17905 c339c812119f3da92b3d40ed56b15586 98 SMART SM00966 14 57 1.5E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_17905 c339c812119f3da92b3d40ed56b15586 98 SUPERFAMILY SSF89447 7 57 1.01E-16 T 15-10-2018 IPR037914 SpoVT-AbrB domain superfamily C2I28_17905 c339c812119f3da92b3d40ed56b15586 98 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 14 54 9.6E-10 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_17905 c339c812119f3da92b3d40ed56b15586 98 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 55 1.2E-11 T 15-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 C2I28_17905 c339c812119f3da92b3d40ed56b15586 98 Gene3D G3DSA:2.10.260.10 2 56 3.8E-25 T 15-10-2018 C2I28_05575 d9447df58d0a34cf924a066bbe381443 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 423 7.9E-154 T 15-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I28_05575 d9447df58d0a34cf924a066bbe381443 451 Pfam PF05525 Branched-chain amino acid transport protein 8 436 7.0E-159 T 15-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.3E-18 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 Gene3D G3DSA:1.10.260.40 1 60 6.1E-21 T 15-10-2018 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 SMART SM00354 2 72 5.4E-32 T 15-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 SUPERFAMILY SSF53822 61 330 3.19E-83 T 15-10-2018 IPR028082 Periplasmic binding protein-like I C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 SUPERFAMILY SSF47413 2 60 2.82E-16 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 Gene3D G3DSA:3.40.50.2300 63 320 2.2E-83 T 15-10-2018 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 Pfam PF13377 Periplasmic binding protein-like domain 169 328 1.7E-38 T 15-10-2018 C2I28_10620 79894898780c585c8e3ecdd625d0e75c 341 Gene3D G3DSA:3.40.50.2300 161 325 2.2E-83 T 15-10-2018 C2I28_11095 9734f2e07f422850f062b4a0fd804c1b 184 Pfam PF10400 Virulence activator alpha C-term 94 180 2.2E-17 T 15-10-2018 IPR018309 Transcription regulator PadR, C-terminal C2I28_11095 9734f2e07f422850f062b4a0fd804c1b 184 Gene3D G3DSA:1.10.10.10 3 88 1.0E-25 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_11095 9734f2e07f422850f062b4a0fd804c1b 184 SUPERFAMILY SSF46785 4 182 4.12E-41 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_11095 9734f2e07f422850f062b4a0fd804c1b 184 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 2.1E-17 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_12200 0518884c0abb56a968ea172980963932 476 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 435 5.9E-157 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 91 106 - T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 PRINTS PR00175 Sodium/alanine symporter signature 209 228 2.0E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 PRINTS PR00175 Sodium/alanine symporter signature 181 199 2.0E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 PRINTS PR00175 Sodium/alanine symporter signature 91 113 2.0E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 PRINTS PR00175 Sodium/alanine symporter signature 300 318 2.0E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 PRINTS PR00175 Sodium/alanine symporter signature 344 366 2.0E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 PRINTS PR00175 Sodium/alanine symporter signature 404 424 2.0E-57 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_12200 0518884c0abb56a968ea172980963932 476 Pfam PF01235 Sodium:alanine symporter family 52 447 6.2E-161 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_25115 b908d17c8d7d1709bdc1e3ad6393ec2e 429 Pfam PF01098 Cell cycle protein 89 416 3.2E-28 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_13915 e159d11faf4413433a9a8ee0008f15f7 123 Pfam PF07238 PilZ domain 39 106 1.9E-9 T 15-10-2018 IPR009875 PilZ domain GO:0035438 C2I28_13915 e159d11faf4413433a9a8ee0008f15f7 123 SUPERFAMILY SSF141371 37 105 5.3E-5 T 15-10-2018 C2I28_13835 263caca80ce8359520de23932b9e2d0f 159 Pfam PF06338 ComK protein 5 148 1.8E-27 T 15-10-2018 IPR010461 Competence protein ComK GO:0030420 C2I28_19560 005d8cda21ffcb0066c2426b01cfefc7 282 PIRSF PIRSF035875 1 281 1.8E-86 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_19560 005d8cda21ffcb0066c2426b01cfefc7 282 Pfam PF03631 Virulence factor BrkB 17 269 4.6E-73 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_19560 005d8cda21ffcb0066c2426b01cfefc7 282 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 6 265 6.2E-53 T 15-10-2018 IPR017039 Virulence factor BrkB C2I28_25615 686afe49abc75f9fe3479cc6adca6957 243 Gene3D G3DSA:3.40.50.300 4 196 1.2E-45 T 15-10-2018 C2I28_25615 686afe49abc75f9fe3479cc6adca6957 243 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 1.1E-5 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_25615 686afe49abc75f9fe3479cc6adca6957 243 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 1.1E-5 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_25615 686afe49abc75f9fe3479cc6adca6957 243 SUPERFAMILY SSF52540 4 179 1.21E-40 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_25615 686afe49abc75f9fe3479cc6adca6957 243 Pfam PF02421 Ferrous iron transport protein B 5 159 7.0E-63 T 15-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 C2I28_01340 073955284f0374e385185e6a2de64edb 188 SUPERFAMILY SSF48498 78 187 4.11E-22 T 15-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily C2I28_01340 073955284f0374e385185e6a2de64edb 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 2.2E-15 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_01340 073955284f0374e385185e6a2de64edb 188 Gene3D G3DSA:1.10.357.10 1 188 4.0E-62 T 15-10-2018 C2I28_01340 073955284f0374e385185e6a2de64edb 188 SUPERFAMILY SSF46689 5 70 7.18E-16 T 15-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 C2I28_01340 073955284f0374e385185e6a2de64edb 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 4.3E-5 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_01340 073955284f0374e385185e6a2de64edb 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 4.3E-5 T 15-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 C2I28_17945 884bd5c39a2c0d11d73074270964428f 214 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 11 195 1.1E-39 T 15-10-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein C2I28_21300 36bcc6b24e2a095d37ca0e8c2227118f 156 SUPERFAMILY SSF50475 22 88 1.68E-5 T 15-10-2018 C2I28_21300 36bcc6b24e2a095d37ca0e8c2227118f 156 Gene3D G3DSA:2.30.110.10 1 141 1.5E-5 T 15-10-2018 IPR012349 FMN-binding split barrel GO:0048037 C2I28_06265 ba5f105304531714f9822b741b2142b7 158 Pfam PF01899 Na+/H+ ion antiporter subunit 9 156 1.7E-42 T 15-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 C2I28_06265 ba5f105304531714f9822b741b2142b7 158 PIRSF PIRSF019239 1 158 1.7E-44 T 15-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 C2I28_06565 3fddd335b595142108d178afe10b8040 116 SMART SM00493 7 81 8.5E-7 T 15-10-2018 IPR006171 TOPRIM domain C2I28_06565 3fddd335b595142108d178afe10b8040 116 SUPERFAMILY SSF110455 4 111 2.75E-34 T 15-10-2018 C2I28_06565 3fddd335b595142108d178afe10b8040 116 Gene3D G3DSA:3.40.1360.20 3 116 1.4E-43 T 15-10-2018 C2I28_23280 6f865660bce03e78c5917073e173b21d 26 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 9 26 3.1E-7 T 15-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 C2I28_23280 6f865660bce03e78c5917073e173b21d 26 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 8 26 1.3E-7 T 15-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 C2I28_14650 e1ce078d2fabf44bd3b26719940cf2be 288 SUPERFAMILY SSF56300 59 286 6.28E-34 T 15-10-2018 C2I28_14650 e1ce078d2fabf44bd3b26719940cf2be 288 Pfam PF00149 Calcineurin-like phosphoesterase 59 224 6.6E-8 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_14650 e1ce078d2fabf44bd3b26719940cf2be 288 Gene3D G3DSA:3.60.21.10 58 258 3.9E-20 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_23515 3d7ceff314330bf5746803901ed30cf2 142 Pfam PF04657 Putative inner membrane exporter, YdcZ 5 140 3.0E-33 T 15-10-2018 IPR006750 Putative inner membrane exporter, YdcZ C2I28_21925 6291774da5f282b83c4b89e4875c7182 710 Pfam PF14345 GDYXXLXY protein 564 707 9.1E-36 T 15-10-2018 IPR025833 GDYXXLXY protein C2I28_21925 6291774da5f282b83c4b89e4875c7182 710 Pfam PF09925 Predicted membrane protein (DUF2157) 8 113 1.7E-17 T 15-10-2018 IPR018677 Domain of unknown function DUF2157 C2I28_13985 85b6e0103b9ab62c8dd3ec2d9effcf50 105 SUPERFAMILY SSF89360 1 101 1.57E-10 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_13985 85b6e0103b9ab62c8dd3ec2d9effcf50 105 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 100 5.8E-19 T 15-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 C2I28_18890 a6a1b878674d38cade826253ee9cc45f 390 PIRSF PIRSF000390 1 381 1.3E-111 T 15-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase C2I28_18890 a6a1b878674d38cade826253ee9cc45f 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 375 1.0E-101 T 15-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase C2I28_18890 a6a1b878674d38cade826253ee9cc45f 390 Gene3D G3DSA:3.40.640.10 1 250 1.1E-86 T 15-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 C2I28_18890 a6a1b878674d38cade826253ee9cc45f 390 SUPERFAMILY SSF53383 11 379 6.39E-103 T 15-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase C2I28_18890 a6a1b878674d38cade826253ee9cc45f 390 Gene3D G3DSA:3.90.1150.10 252 386 2.5E-40 T 15-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 C2I28_11485 5a59b8b26cbd3bc7ce6cb76a3b424532 472 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_11485 5a59b8b26cbd3bc7ce6cb76a3b424532 472 Pfam PF00324 Amino acid permease 18 462 4.7E-130 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_11485 5a59b8b26cbd3bc7ce6cb76a3b424532 472 Gene3D G3DSA:1.20.1740.10 8 471 3.7E-64 T 15-10-2018 C2I28_11485 5a59b8b26cbd3bc7ce6cb76a3b424532 472 PIRSF PIRSF006060 1 470 2.6E-79 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_19635 fff64e2abd590a781a7a73c7dc3e67aa 55 Pfam PF13076 Fur-regulated basic protein A 10 42 4.7E-9 T 15-10-2018 IPR025072 Fur-regulated basic protein A C2I28_19950 49e35eb3560adaa151ddb1684a396c71 92 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 2 90 7.0E-44 T 15-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU C2I28_19950 49e35eb3560adaa151ddb1684a396c71 92 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 50 1.5E-10 T 15-10-2018 IPR022453 Zinc finger, MqsA-type C2I28_19950 49e35eb3560adaa151ddb1684a396c71 92 Pfam PF14122 YokU-like protein, putative antitoxin 2 88 2.6E-41 T 15-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU C2I28_01925 83daec374d0efba0889ef2ed6e57683d 161 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 4 150 4.8E-30 T 15-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase C2I28_01925 83daec374d0efba0889ef2ed6e57683d 161 PIRSF PIRSF030780 2 157 3.5E-16 T 15-10-2018 IPR016956 Inner membrane protein YdjM C2I28_22800 c166118996f5b2820b4f58be6d016cb1 80 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.2E-17 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_06370 a50e20870f1766e8cee6d9b7e90994a2 215 Pfam PF06725 3D domain 125 186 1.6E-18 T 15-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 C2I28_06370 a50e20870f1766e8cee6d9b7e90994a2 215 SUPERFAMILY SSF50685 125 166 9.77E-7 T 15-10-2018 IPR036908 RlpA-like domain superfamily C2I28_21255 31a9584777d643af6ebc34101e6f1693 427 SUPERFAMILY SSF111352 10 384 4.97E-108 T 15-10-2018 C2I28_21255 31a9584777d643af6ebc34101e6f1693 427 Gene3D G3DSA:1.10.3430.10 1 421 4.4E-137 T 15-10-2018 IPR029020 Ammonium/urea transporter C2I28_21255 31a9584777d643af6ebc34101e6f1693 427 Pfam PF00909 Ammonium Transporter Family 14 403 4.3E-115 T 15-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 C2I28_21255 31a9584777d643af6ebc34101e6f1693 427 TIGRFAM TIGR00836 amt: ammonium transporter 11 403 1.5E-121 T 15-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 C2I28_21255 31a9584777d643af6ebc34101e6f1693 427 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 15-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 C2I28_11410 94767acf6c22efbf60f90ab8241706f6 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 2.1E-29 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_09090 a7ee79e14e2741ccb7741f6c98f9d43f 295 Pfam PF03116 NQR2, RnfD, RnfE family 43 159 1.1E-10 T 15-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 C2I28_09090 a7ee79e14e2741ccb7741f6c98f9d43f 295 Pfam PF03116 NQR2, RnfD, RnfE family 170 279 1.8E-8 T 15-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 C2I28_14345 e0dbaaa9ebd082bfe9751bb7d78ed76e 243 Pfam PF02535 ZIP Zinc transporter 101 239 2.7E-15 T 15-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 SUPERFAMILY SSF56645 4 272 6.57E-78 T 15-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 Gene3D G3DSA:2.40.110.10 147 272 7.3E-43 T 15-10-2018 C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 Gene3D G3DSA:1.20.140.10 274 478 3.4E-71 T 15-10-2018 C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 Gene3D G3DSA:1.10.3140.10 3 146 1.1E-48 T 15-10-2018 C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 PIRSF PIRSF000331 1 478 3.2E-151 T 15-10-2018 IPR004925 HpaB/PvcC/4-BUDH C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 4 478 1.1E-165 T 15-10-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 279 476 3.5E-56 T 15-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 270 8.9E-94 T 15-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal C2I28_20110 ea22f2c317a542de0f8a2ecf308675bb 478 SUPERFAMILY SSF47203 262 477 2.99E-52 T 15-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 C2I28_10590 73260f5b69846fa92ce2774bee96088c 426 SUPERFAMILY SSF103473 19 408 1.44E-47 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_10590 73260f5b69846fa92ce2774bee96088c 426 Pfam PF07690 Major Facilitator Superfamily 41 313 1.5E-16 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_10590 73260f5b69846fa92ce2774bee96088c 426 TIGRFAM TIGR00897 2A0118: polyol permease 9 406 1.2E-180 T 15-10-2018 IPR004748 Polyol permease GO:0016021|GO:0022857|GO:0055085 C2I28_10590 73260f5b69846fa92ce2774bee96088c 426 Gene3D G3DSA:1.20.1250.20 11 207 6.0E-15 T 15-10-2018 C2I28_10590 73260f5b69846fa92ce2774bee96088c 426 Gene3D G3DSA:1.20.1250.20 220 413 3.1E-19 T 15-10-2018 C2I28_27720 4013856cd027312a788fff21dfeb3f15 110 Gene3D G3DSA:2.60.40.10 3 90 1.8E-8 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27720 4013856cd027312a788fff21dfeb3f15 110 SUPERFAMILY SSF49313 8 94 5.85E-9 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 Gene3D G3DSA:3.40.50.720 1 284 2.7E-89 T 15-10-2018 C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 SUPERFAMILY SSF51735 42 284 6.04E-82 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 192 211 5.2E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 131 5.2E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 180 5.2E-10 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 211 1.3E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 182 1.3E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 230 1.3E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 45 62 1.3E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 131 1.3E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 247 267 1.3E-37 T 15-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 53 282 2.0E-63 T 15-10-2018 C2I28_11495 ce6a82ac7b4b63f493bb69f31fe97d63 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 179 207 - T 15-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 C2I28_17790 0493a3e71996cbc7aee44ab5338f6923 202 Pfam PF01955 Adenosylcobinamide amidohydrolase 5 191 3.3E-46 T 15-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ C2I28_10840 659358167e5dedb28a6f0b8ed0e53871 469 Pfam PF04293 SpoVR like protein 5 407 6.2E-163 T 15-10-2018 IPR007390 Sporulation stage V, protein R C2I28_13390 810f8c218f19160fe7f8c0fb3f81bacd 320 Pfam PF01758 Sodium Bile acid symporter family 42 219 6.4E-45 T 15-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 C2I28_13390 810f8c218f19160fe7f8c0fb3f81bacd 320 Gene3D G3DSA:1.20.1530.20 1 306 2.0E-110 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_10705 c7853e7cab7537302a2482872c522b47 147 Pfam PF10787 Uncharacterised protein from bacillus cereus group 1 141 3.1E-56 T 15-10-2018 IPR019723 Uncharacterised protein, YfmQ C2I28_04585 b8fc5da93b8f0c543af9e928df0c4d1d 367 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 17 361 6.8E-113 T 15-10-2018 IPR003770 Endolytic murein transglycosylase C2I28_04585 b8fc5da93b8f0c543af9e928df0c4d1d 367 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 19 362 34.379 T 15-10-2018 IPR003770 Endolytic murein transglycosylase C2I28_04585 b8fc5da93b8f0c543af9e928df0c4d1d 367 Gene3D G3DSA:1.10.8.1150 47 121 1.9E-25 T 15-10-2018 C2I28_04585 b8fc5da93b8f0c543af9e928df0c4d1d 367 Pfam PF02618 YceG-like family 53 354 7.4E-82 T 15-10-2018 IPR003770 Endolytic murein transglycosylase C2I28_21415 2a1a0b0823a6d533f6adc43904bc544b 178 Pfam PF16800 IseA DL-endopeptidase inhibitor 29 176 5.0E-51 T 15-10-2018 IPR031841 DL-endopeptidase inhibitor IseA C2I28_21415 2a1a0b0823a6d533f6adc43904bc544b 178 Gene3D G3DSA:3.10.450.420 25 178 1.4E-51 T 15-10-2018 C2I28_22770 d120a159c2fb63b3c4e71ff676e6f7f4 310 SUPERFAMILY SSF53474 43 309 1.77E-43 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_22770 d120a159c2fb63b3c4e71ff676e6f7f4 310 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 81 222 6.1E-13 T 15-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 C2I28_22770 d120a159c2fb63b3c4e71ff676e6f7f4 310 Gene3D G3DSA:3.40.50.1820 52 308 2.7E-42 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_04615 2ff069226c52c85695db35237b6ed961 44 Pfam PF13056 Protein of unknown function (DUF3918) 1 43 2.0E-21 T 15-10-2018 IPR025029 Protein of unknown function DUF3918 C2I28_10450 cdcc19501a971e0d2bda93e275d13465 192 SUPERFAMILY SSF110391 16 189 8.76E-56 T 15-10-2018 IPR035928 GlpP-like superfamily C2I28_10450 cdcc19501a971e0d2bda93e275d13465 192 Gene3D G3DSA:3.20.20.400 7 192 4.1E-67 T 15-10-2018 IPR035928 GlpP-like superfamily C2I28_10450 cdcc19501a971e0d2bda93e275d13465 192 PIRSF PIRSF016897 5 192 4.9E-64 T 15-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I28_10450 cdcc19501a971e0d2bda93e275d13465 192 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 17 188 2.3E-62 T 15-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 C2I28_18925 44b3abacfa92e984146a3cb762032be5 395 Pfam PF00534 Glycosyl transferases group 1 227 373 2.2E-28 T 15-10-2018 IPR001296 Glycosyl transferase, family 1 C2I28_18925 44b3abacfa92e984146a3cb762032be5 395 Gene3D G3DSA:3.40.50.2000 122 204 2.0E-42 T 15-10-2018 C2I28_18925 44b3abacfa92e984146a3cb762032be5 395 Gene3D G3DSA:3.40.50.2000 205 375 2.0E-42 T 15-10-2018 C2I28_18925 44b3abacfa92e984146a3cb762032be5 395 SUPERFAMILY SSF53756 6 392 1.61E-47 T 15-10-2018 C2I28_26720 3cd87d2f634546b69d176e6d9e0472c7 110 Pfam PF08863 YolD-like protein 14 107 4.6E-18 T 15-10-2018 IPR014962 YolD-like protein C2I28_00135 c91bde38ecff7215752901f344d41818 393 Pfam PF00999 Sodium/hydrogen exchanger family 7 387 4.1E-66 T 15-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 C2I28_00135 c91bde38ecff7215752901f344d41818 393 Gene3D G3DSA:1.20.1530.20 2 389 1.1E-16 T 15-10-2018 IPR038770 Sodium/solute symporter superfamily C2I28_12400 7bd8330e86e2cbc8835b4e36c7529381 60 Pfam PF08863 YolD-like protein 1 59 1.8E-9 T 15-10-2018 IPR014962 YolD-like protein C2I28_00950 7bc4ffcfcc3e6534328ad2d5376a662f 146 Pfam PF14040 Deoxyribonuclease NucA/NucB 51 135 3.7E-11 T 15-10-2018 IPR029476 Deoxyribonuclease NucA/NucB C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 9.8E-112 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 5 430 3.2E-222 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_16690 7958adcb9d956c04c36252a9ebf1e255 432 Pfam PF02040 Arsenical pump membrane protein 7 428 9.2E-227 T 15-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 C2I28_11340 4d4d6e1f0ca0c37390a808914d8d2a32 78 Pfam PF08858 IDEAL domain 34 70 6.6E-14 T 15-10-2018 IPR014957 IDEAL domain C2I28_11340 4d4d6e1f0ca0c37390a808914d8d2a32 78 SMART SM00914 34 70 1.4E-10 T 15-10-2018 IPR014957 IDEAL domain C2I28_11340 4d4d6e1f0ca0c37390a808914d8d2a32 78 Gene3D G3DSA:4.10.810.10 19 77 7.1E-11 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_04490 89303b59321737f9a07f120593b52bfe 46 Pfam PF08970 Sporulation inhibitor A 1 44 7.1E-24 T 15-10-2018 IPR015064 Sporulation inhibitor A C2I28_04490 89303b59321737f9a07f120593b52bfe 46 SUPERFAMILY SSF100985 1 44 4.84E-17 T 15-10-2018 IPR036916 Sporulation inhibitor A superfamily C2I28_04490 89303b59321737f9a07f120593b52bfe 46 Gene3D G3DSA:1.10.287.1100 4 37 5.5E-19 T 15-10-2018 IPR036916 Sporulation inhibitor A superfamily C2I28_18675 70e1e8392fe7a49e1506e2f3c3fdfe27 303 SUPERFAMILY SSF103481 206 298 1.2E-10 T 15-10-2018 C2I28_18675 70e1e8392fe7a49e1506e2f3c3fdfe27 303 SUPERFAMILY SSF103481 49 152 7.45E-9 T 15-10-2018 C2I28_18675 70e1e8392fe7a49e1506e2f3c3fdfe27 303 Pfam PF00892 EamA-like transporter family 162 295 1.8E-27 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_18675 70e1e8392fe7a49e1506e2f3c3fdfe27 303 Pfam PF00892 EamA-like transporter family 12 149 1.7E-21 T 15-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 C2I28_03475 d1bdb20ae013b9c9705c700340a94d7f 291 Pfam PF06207 Protein of unknown function (DUF1002) 37 254 6.4E-79 T 15-10-2018 IPR009343 Protein of unknown function DUF1002 C2I28_24580 8891750002730a3cc21d2552ec8da0e0 108 Gene3D G3DSA:1.10.10.10 7 107 4.1E-15 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24580 8891750002730a3cc21d2552ec8da0e0 108 Pfam PF03551 Transcriptional regulator PadR-like family 20 88 5.0E-8 T 15-10-2018 IPR005149 Transcription regulator PadR, N-terminal C2I28_24580 8891750002730a3cc21d2552ec8da0e0 108 SUPERFAMILY SSF46785 15 107 6.68E-14 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_03905 efea03e9b968e064252820256f094508 170 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 2 170 4.4E-53 T 15-10-2018 IPR014198 Stage III sporulation protein AB C2I28_03905 efea03e9b968e064252820256f094508 170 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 2 170 2.8E-62 T 15-10-2018 IPR014198 Stage III sporulation protein AB C2I28_03905 efea03e9b968e064252820256f094508 170 PIRSF PIRSF021435 1 170 1.4E-62 T 15-10-2018 IPR014198 Stage III sporulation protein AB C2I28_24675 3b8c39152f5224facccd6205a9c14d80 163 SUPERFAMILY SSF55729 5 147 4.97E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_24675 3b8c39152f5224facccd6205a9c14d80 163 Gene3D G3DSA:3.40.630.30 4 163 2.8E-42 T 15-10-2018 C2I28_24675 3b8c39152f5224facccd6205a9c14d80 163 Pfam PF00583 Acetyltransferase (GNAT) family 25 137 6.1E-13 T 15-10-2018 IPR000182 GNAT domain C2I28_02625 2d25c80c83e7754b2528e0dbf66dbe1b 127 Pfam PF11068 YlqD protein 1 127 2.7E-35 T 15-10-2018 IPR021297 YlqD protein C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 PIRSF PIRSF005900 1 147 2.4E-50 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 Gene3D G3DSA:1.20.1260.10 1 145 1.8E-53 T 15-10-2018 IPR012347 Ferritin-like C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 SUPERFAMILY SSF47240 4 142 2.88E-43 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 ProSitePatterns PS00818 Dps protein family signature 1. 25 41 - T 15-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 25 41 7.2E-16 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 49 65 7.2E-16 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 120 138 7.2E-16 T 15-10-2018 IPR002177 DNA-binding protein Dps C2I28_23075 09e00e710aa607f1bfbe60dc37aa0e16 150 Pfam PF00210 Ferritin-like domain 5 142 1.8E-32 T 15-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I28_15745 e5fbe9699ab285a1b48520710ec74963 204 Pfam PF01810 LysE type translocator 15 202 2.0E-30 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_10760 31a87e4153adaedb584087c10906db08 291 Gene3D G3DSA:3.30.70.1350 203 286 1.8E-15 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_10760 31a87e4153adaedb584087c10906db08 291 SUPERFAMILY SSF160240 208 284 5.75E-17 T 15-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 C2I28_10760 31a87e4153adaedb584087c10906db08 291 Gene3D G3DSA:1.20.1510.10 8 202 1.5E-51 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_10760 31a87e4153adaedb584087c10906db08 291 Pfam PF01545 Cation efflux family 13 204 4.6E-46 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_10760 31a87e4153adaedb584087c10906db08 291 SUPERFAMILY SSF161111 6 206 1.44E-51 T 15-10-2018 IPR027469 Cation efflux transmembrane domain superfamily C2I28_10760 31a87e4153adaedb584087c10906db08 291 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 285 2.0E-66 T 15-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 C2I28_10760 31a87e4153adaedb584087c10906db08 291 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 284 1.3E-17 T 15-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 274 328 - T 15-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 405 424 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 118 142 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 221 240 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 272 293 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 342 363 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 210 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 318 333 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 160 172 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 377 395 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 455 476 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 44 69 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 114 1.3E-98 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 2 640 0.0 T 15-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 53 499 5.6E-144 T 15-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 Gene3D G3DSA:1.20.210.10 28 558 2.3E-199 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_23755 23ab8032fd8951c39a2dbf894afcabdd 647 SUPERFAMILY SSF81442 42 552 4.06E-178 T 15-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 C2I28_17470 0ad0290d6557a4f29bf9c3d3883dda8f 81 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 3 75 3.8E-25 T 15-10-2018 IPR018680 Protein of unknown function DUF2164 C2I28_21325 ff517c5eeb2a195be5c8210ddd76379a 318 Pfam PF03547 Membrane transport protein 9 158 3.0E-23 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_21325 ff517c5eeb2a195be5c8210ddd76379a 318 Pfam PF03547 Membrane transport protein 162 313 1.5E-17 T 15-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 C2I28_22670 23ba8753a8eab8f1654d1d6e8d4329ea 148 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 140 1.1E-67 T 15-10-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes C2I28_22670 23ba8753a8eab8f1654d1d6e8d4329ea 148 SUPERFAMILY SSF82784 3 140 1.18E-34 T 15-10-2018 IPR036102 OsmC/Ohr superfamily C2I28_22670 23ba8753a8eab8f1654d1d6e8d4329ea 148 Pfam PF02566 OsmC-like protein 39 141 7.6E-20 T 15-10-2018 IPR003718 OsmC/Ohr family C2I28_22670 23ba8753a8eab8f1654d1d6e8d4329ea 148 Gene3D G3DSA:3.30.300.20 6 145 3.2E-33 T 15-10-2018 IPR015946 K homology domain-like, alpha/beta C2I28_17000 30fbae97104d070569e1b9f489534dad 185 Pfam PF13079 Protein of unknown function (DUF3916) 31 182 2.5E-20 T 15-10-2018 IPR025075 Protein of unknown function DUF3916 C2I28_11195 d5d75854c42fec645d91ced536df3eb8 43 Pfam PF14149 YhfH-like protein 2 38 6.3E-20 T 15-10-2018 IPR025432 YhfH-like protein C2I28_00700 be454ffcbd9fb46167e426b0064d528f 49 Pfam PF13070 Protein of unknown function (DUF3934) 1 40 1.3E-22 T 15-10-2018 IPR025175 Protein of unknown function DUF3934 C2I28_00650 5d6b0d20531dcc2d47e244a0fbdbc0a9 214 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 13 207 8.0E-36 T 15-10-2018 IPR006214 Bax inhibitor 1-related C2I28_25945 65bfc28ff30fe143c7e5af7532b2432e 111 Gene3D G3DSA:1.10.10.10 6 110 2.1E-37 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_25945 65bfc28ff30fe143c7e5af7532b2432e 111 SUPERFAMILY SSF46785 9 107 1.25E-32 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_25945 65bfc28ff30fe143c7e5af7532b2432e 111 Pfam PF01638 HxlR-like helix-turn-helix 22 108 2.1E-33 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_12365 ade4acbeb210d80b3f5d17587661e0c2 286 SUPERFAMILY SSF103481 196 274 7.59E-7 T 15-10-2018 C2I28_12365 ade4acbeb210d80b3f5d17587661e0c2 286 Pfam PF06800 Sugar transport protein 5 283 6.8E-111 T 15-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 C2I28_12365 ade4acbeb210d80b3f5d17587661e0c2 286 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 285 2.6E-118 T 15-10-2018 C2I28_12365 ade4acbeb210d80b3f5d17587661e0c2 286 SUPERFAMILY SSF103481 36 138 9.42E-9 T 15-10-2018 C2I28_25425 c1a8431d4ca1d66645d75c3bbef3f17a 376 Pfam PF03845 Spore germination protein 5 324 2.1E-79 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_25425 c1a8431d4ca1d66645d75c3bbef3f17a 376 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 364 1.8E-72 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_22605 9092a86a8e7f8ea09d89173617ee5976 223 Gene3D G3DSA:3.30.240.20 78 153 1.8E-21 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_22605 9092a86a8e7f8ea09d89173617ee5976 223 Gene3D G3DSA:3.30.240.20 166 223 7.6E-17 T 15-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily C2I28_22605 9092a86a8e7f8ea09d89173617ee5976 223 Pfam PF04239 Protein of unknown function (DUF421) 87 202 1.1E-31 T 15-10-2018 IPR007353 Protein of unknown function DUF421 C2I28_15615 918aa5f06f65f25aa60a6e1e029156d1 65 SUPERFAMILY SSF47413 4 60 1.23E-8 T 15-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 C2I28_15615 918aa5f06f65f25aa60a6e1e029156d1 65 Gene3D G3DSA:1.10.260.40 1 62 3.5E-7 T 15-10-2018 C2I28_17275 ba2bfa6931a153d2b48f5162510c3e54 327 SUPERFAMILY SSF51412 1 315 1.43E-63 T 15-10-2018 C2I28_17275 ba2bfa6931a153d2b48f5162510c3e54 327 Pfam PF03060 Nitronate monooxygenase 3 306 5.8E-60 T 15-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 C2I28_17275 ba2bfa6931a153d2b48f5162510c3e54 327 Gene3D G3DSA:3.20.20.70 1 321 4.6E-110 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 Gene3D G3DSA:3.40.50.150 182 398 1.5E-63 T 15-10-2018 C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 159 380 1.3E-32 T 15-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 SUPERFAMILY SSF88697 7 74 1.79E-17 T 15-10-2018 IPR015947 PUA-like superfamily C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 Gene3D G3DSA:2.30.130.10 5 73 2.1E-21 T 15-10-2018 IPR036974 PUA domain superfamily GO:0003723 C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 SMART SM00359 5 90 0.0015 T 15-10-2018 IPR002478 PUA domain GO:0003723 C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 SUPERFAMILY SSF53335 81 393 3.49E-68 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_07795 f9f26f0028ffd07e18e785eaa5925b10 399 Gene3D G3DSA:3.30.750.80 74 181 1.1E-34 T 15-10-2018 C2I28_26785 ca806a519836203355d148d5dcb1e9c0 401 SUPERFAMILY SSF53448 33 308 6.33E-50 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_26785 ca806a519836203355d148d5dcb1e9c0 401 Pfam PF13641 Glycosyltransferase like family 2 35 262 1.6E-30 T 15-10-2018 C2I28_26785 ca806a519836203355d148d5dcb1e9c0 401 Gene3D G3DSA:3.90.550.10 21 252 3.4E-39 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_04330 500ff543164783e42a724acdf7361c77 94 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 9 92 9.9E-35 T 15-10-2018 IPR022477 Sporulation protein YqfC C2I28_04330 500ff543164783e42a724acdf7361c77 94 Pfam PF07873 YabP family 28 91 6.1E-19 T 15-10-2018 IPR022476 Sporulation protein YabP/YqfC C2I28_07085 1608f62330039cc0244095114e940118 601 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 9 104 2.3E-22 T 15-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 C2I28_07085 1608f62330039cc0244095114e940118 601 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 330 591 1.8E-54 T 15-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 C2I28_18985 444f74e7c03a22767b740e4eb5f450cf 262 SUPERFAMILY SSF53795 117 174 6.18E-7 T 15-10-2018 C2I28_18985 444f74e7c03a22767b740e4eb5f450cf 262 Gene3D G3DSA:3.40.50.300 100 251 5.3E-5 T 15-10-2018 C2I28_21790 d207dd21b460c00af31e11294229770f 309 Pfam PF03747 ADP-ribosylglycohydrolase 11 287 3.8E-66 T 15-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 C2I28_21790 d207dd21b460c00af31e11294229770f 309 Gene3D G3DSA:1.10.4080.10 2 309 3.6E-87 T 15-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily C2I28_21790 d207dd21b460c00af31e11294229770f 309 SUPERFAMILY SSF101478 2 307 7.45E-71 T 15-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily C2I28_01625 4651224f91b993e42a1e431001137908 280 Pfam PF00005 ABC transporter 20 154 4.4E-28 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_01625 4651224f91b993e42a1e431001137908 280 SMART SM00382 29 203 6.9E-13 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_01625 4651224f91b993e42a1e431001137908 280 SUPERFAMILY SSF52540 3 205 5.94E-50 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_01625 4651224f91b993e42a1e431001137908 280 Gene3D G3DSA:3.40.50.300 1 233 1.1E-50 T 15-10-2018 C2I28_23745 e2f4e003aa4a9cfd4c6d1b71d76d300e 102 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 8 98 6.9E-33 T 15-10-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 C2I28_23745 e2f4e003aa4a9cfd4c6d1b71d76d300e 102 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 17 89 6.2E-12 T 15-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 C2I28_18745 aac040cfa9309329376401bcee14c00a 257 Pfam PF01925 Sulfite exporter TauE/SafE 12 244 8.3E-39 T 15-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I28_13690 1d741621cc378a6a61589050d57f9d74 239 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 230 2.5E-67 T 15-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 C2I28_13690 1d741621cc378a6a61589050d57f9d74 239 SUPERFAMILY SSF53448 1 237 9.69E-64 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_13690 1d741621cc378a6a61589050d57f9d74 239 Pfam PF02348 Cytidylyltransferase 4 209 3.0E-56 T 15-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 C2I28_13690 1d741621cc378a6a61589050d57f9d74 239 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 238 38.246 T 15-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 C2I28_13690 1d741621cc378a6a61589050d57f9d74 239 Gene3D G3DSA:3.90.550.10 1 239 2.6E-86 T 15-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases C2I28_22520 232a9e56452bce1c8488172dbb277036 296 SMART SM00382 27 205 8.5E-14 T 15-10-2018 IPR003593 AAA+ ATPase domain C2I28_22520 232a9e56452bce1c8488172dbb277036 296 SUPERFAMILY SSF52540 3 219 3.7E-59 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_22520 232a9e56452bce1c8488172dbb277036 296 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 15-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 C2I28_22520 232a9e56452bce1c8488172dbb277036 296 Pfam PF00005 ABC transporter 18 157 1.2E-32 T 15-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 C2I28_22520 232a9e56452bce1c8488172dbb277036 296 Gene3D G3DSA:3.40.50.300 2 224 6.5E-63 T 15-10-2018 C2I28_22520 232a9e56452bce1c8488172dbb277036 296 Pfam PF13732 Domain of unknown function (DUF4162) 210 293 2.0E-7 T 15-10-2018 IPR025302 Domain of unknown function DUF4162 C2I28_04990 5e28b51fb12b35c867e2f1b1426928a5 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 1.1E-70 T 15-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 C2I28_04990 5e28b51fb12b35c867e2f1b1426928a5 195 Gene3D G3DSA:3.40.50.300 1 192 4.8E-54 T 15-10-2018 C2I28_04990 5e28b51fb12b35c867e2f1b1426928a5 195 Pfam PF01926 50S ribosome-binding GTPase 26 143 1.2E-20 T 15-10-2018 IPR006073 GTP binding domain GO:0005525 C2I28_04990 5e28b51fb12b35c867e2f1b1426928a5 195 SUPERFAMILY SSF52540 16 190 2.78E-37 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_04990 5e28b51fb12b35c867e2f1b1426928a5 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.291 T 15-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 C2I28_19525 50c7f41a054a65aa7349df119b9c55c1 120 SUPERFAMILY SSF54593 1 119 9.13E-19 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_19525 50c7f41a054a65aa7349df119b9c55c1 120 Gene3D G3DSA:3.10.180.10 6 118 2.5E-27 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_19525 50c7f41a054a65aa7349df119b9c55c1 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 7.0E-7 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_12015 c5fc276c8e29fb3ab5aba5094eefbb79 112 Pfam PF11181 Heat induced stress protein YflT 4 103 1.5E-21 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_24780 45db9a352c51a7fcd13d02d3dc4a0db3 329 Pfam PF13170 Protein of unknown function (DUF4003) 17 311 3.8E-91 T 15-10-2018 IPR025062 Protein of unknown function DUF4003 C2I28_10655 73a709848d18eeaa786ea07570a0c946 81 SUPERFAMILY SSF81342 10 53 2.98E-5 T 15-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 C2I28_10655 73a709848d18eeaa786ea07570a0c946 81 Gene3D G3DSA:1.20.810.10 2 73 1.4E-5 T 15-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 C2I28_03900 2ad067d00397d246928ddff9723ac2bb 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 8.9E-17 T 15-10-2018 IPR025664 Stage III sporulation protein AC/AD family C2I28_03900 2ad067d00397d246928ddff9723ac2bb 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 2.3E-29 T 15-10-2018 IPR009570 Stage III sporulation protein AC C2I28_21540 8f61b9fc4682480386974f1921dd381e 551 Pfam PF07690 Major Facilitator Superfamily 39 422 4.9E-23 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_21540 8f61b9fc4682480386974f1921dd381e 551 SUPERFAMILY SSF103473 27 527 9.16E-33 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21540 8f61b9fc4682480386974f1921dd381e 551 Gene3D G3DSA:1.20.1250.20 17 203 1.3E-19 T 15-10-2018 C2I28_17535 4797db46d307c11e42858251ea05f821 106 Gene3D G3DSA:3.10.20.30 4 91 9.5E-21 T 15-10-2018 IPR012675 Beta-grasp domain superfamily C2I28_17535 4797db46d307c11e42858251ea05f821 106 SUPERFAMILY SSF54292 11 89 7.12E-20 T 15-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 C2I28_17535 4797db46d307c11e42858251ea05f821 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 81 4.2E-14 T 15-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 C2I28_18670 a6062caa3839922bdbcdb6148b7e7fba 638 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 433 622 5.0E-7 T 15-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 C2I28_18670 a6062caa3839922bdbcdb6148b7e7fba 638 SMART SM00327 443 627 6.7E-11 T 15-10-2018 IPR002035 von Willebrand factor, type A C2I28_18670 a6062caa3839922bdbcdb6148b7e7fba 638 SUPERFAMILY SSF53300 447 632 2.23E-14 T 15-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I28_18670 a6062caa3839922bdbcdb6148b7e7fba 638 Gene3D G3DSA:3.40.50.410 438 635 8.3E-9 T 15-10-2018 IPR036465 von Willebrand factor A-like domain superfamily C2I28_22910 8f871e0cfec546e0c8bccb6c0989997f 237 Pfam PF01553 Acyltransferase 29 156 2.0E-12 T 15-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I28_22910 8f871e0cfec546e0c8bccb6c0989997f 237 SMART SM00563 42 159 4.0E-13 T 15-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 C2I28_22910 8f871e0cfec546e0c8bccb6c0989997f 237 SUPERFAMILY SSF69593 14 207 4.05E-17 T 15-10-2018 C2I28_06270 bd31977492263cb25f5f43d14feab090 94 PIRSF PIRSF028784 1 92 4.3E-30 T 15-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 C2I28_06270 bd31977492263cb25f5f43d14feab090 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 83 9.4E-19 T 15-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 C2I28_27730 b9630ec4d23006a6bb0614935ff2a067 82 SUPERFAMILY SSF49313 4 81 7.72E-7 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_27730 b9630ec4d23006a6bb0614935ff2a067 82 Gene3D G3DSA:2.60.40.10 2 81 8.4E-9 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_02495 7dd62021aef3837e0d6626e1913e6888 142 Pfam PF03963 Flagellar hook capping protein - N-terminal region 12 74 2.2E-23 T 15-10-2018 IPR005648 Flagellar hook capping protein C2I28_17420 22e4ba88cccd826a4d1ec899575417c7 363 Pfam PF01594 AI-2E family transporter 18 349 7.7E-83 T 15-10-2018 IPR002549 Transmembrane protein TqsA-like C2I28_20585 96a1f998c0eb2fa146dfcfbbae92a8a9 185 Gene3D G3DSA:1.10.1760.20 1 177 7.2E-51 T 15-10-2018 C2I28_20585 96a1f998c0eb2fa146dfcfbbae92a8a9 185 Pfam PF02632 BioY family 29 172 2.3E-34 T 15-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I28_20585 96a1f998c0eb2fa146dfcfbbae92a8a9 185 PIRSF PIRSF016661 1 176 2.6E-43 T 15-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 C2I28_24410 a1d31c839a705ee1849ce50175910d3a 255 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 8 247 8.2E-54 T 15-10-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 C2I28_19540 e3db454f8b67878583596f0bd9867847 99 ProDom PD068665 YXCD 1 77 1.0E-24 T 15-10-2018 IPR020516 Uncharacterised protein family YxcD C2I28_19540 e3db454f8b67878583596f0bd9867847 99 Pfam PF10850 Protein of unknown function (DUF2653) 1 88 4.8E-39 T 15-10-2018 IPR020516 Uncharacterised protein family YxcD C2I28_05330 a9ce54a4f8821cf5ccc9841de0320f66 310 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 2.4E-28 T 15-10-2018 IPR009928 Primosomal DnaI, N-terminal C2I28_05330 a9ce54a4f8821cf5ccc9841de0320f66 310 Pfam PF01695 IstB-like ATP binding protein 130 272 1.8E-10 T 15-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 C2I28_05330 a9ce54a4f8821cf5ccc9841de0320f66 310 SUPERFAMILY SSF52540 125 273 1.58E-19 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_05330 a9ce54a4f8821cf5ccc9841de0320f66 310 Gene3D G3DSA:3.40.50.300 108 302 1.5E-50 T 15-10-2018 C2I28_25210 ee7d1f7762cf2acc089a3f209a596029 275 Pfam PF12730 ABC-2 family transporter protein 4 198 2.9E-6 T 15-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I28_03225 4519d101b95da0c3b4db5f1e9b50cdf3 264 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 24 219 3.3E-51 T 15-10-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 15-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 1.3E-94 T 15-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 PIRSF PIRSF001461 1 218 6.3E-100 T 15-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 SUPERFAMILY SSF51366 1 213 1.33E-78 T 15-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 Gene3D G3DSA:3.20.20.70 2 218 3.2E-93 T 15-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 9.7E-90 T 15-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I28_02735 9dbf4eb7368b1742798a68b7e2bc3c4d 218 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 15-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 C2I28_11415 68ca42da6eefaf7d24106264e9600809 390 Pfam PF04235 Protein of unknown function (DUF418) 234 388 2.5E-35 T 15-10-2018 IPR007349 Domain of unknown function DUF418 C2I28_04645 8d48110475733c7e901c54eb190f26bf 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 15-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site C2I28_04645 8d48110475733c7e901c54eb190f26bf 138 SUPERFAMILY SSF46785 2 126 1.99E-32 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_04645 8d48110475733c7e901c54eb190f26bf 138 Gene3D G3DSA:1.10.10.10 1 138 1.3E-51 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_04645 8d48110475733c7e901c54eb190f26bf 138 Pfam PF02082 Transcriptional regulator 1 82 5.8E-27 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_04645 8d48110475733c7e901c54eb190f26bf 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 124 1.4E-34 T 15-10-2018 IPR000944 Transcription regulator Rrf2-type C2I28_01710 801ef994f28fda75eb630f9e849e4fec 256 SUPERFAMILY SSF81296 17 114 7.7E-5 T 15-10-2018 IPR014756 Immunoglobulin E-set C2I28_01710 801ef994f28fda75eb630f9e849e4fec 256 Pfam PF07070 SpoOM protein 4 214 4.5E-75 T 15-10-2018 IPR009776 Sporulation stage 0, protein M C2I28_24425 4514aa3e3cd4e2d19385ae851391de18 88 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 12 26 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24425 4514aa3e3cd4e2d19385ae851391de18 88 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 45 58 - T 15-10-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 C2I28_24425 4514aa3e3cd4e2d19385ae851391de18 88 Pfam PF00741 Gas vesicle protein 11 49 1.1E-15 T 15-10-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 C2I28_24425 4514aa3e3cd4e2d19385ae851391de18 88 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 4 87 24.799 T 15-10-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 C2I28_25375 e1430ae7241c75b152beb0b576745102 313 Pfam PF01544 CorA-like Mg2+ transporter protein 7 294 2.3E-35 T 15-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 C2I28_25375 e1430ae7241c75b152beb0b576745102 313 Gene3D G3DSA:1.20.58.340 223 299 4.0E-21 T 15-10-2018 C2I28_25375 e1430ae7241c75b152beb0b576745102 313 SUPERFAMILY SSF144083 235 296 8.63E-18 T 15-10-2018 C2I28_25375 e1430ae7241c75b152beb0b576745102 313 SUPERFAMILY SSF143865 7 197 1.28E-5 T 15-10-2018 C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 Gene3D G3DSA:3.40.50.1450 1 296 5.0E-119 T 15-10-2018 IPR023430 Peptidase HybD-like domain superfamily C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 370 5.8E-180 T 15-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 Hamap MF_00626 Germination protease [gpr]. 1 370 156.144 T 15-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 PIRSF PIRSF019549 3 370 8.0E-188 T 15-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 Pfam PF03418 Germination protease 17 369 1.4E-188 T 15-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 9 370 0.0 T 15-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 C2I28_04410 18599de52609b3cf2869dfe5cf100d99 370 SUPERFAMILY SSF53163 2 370 2.75E-133 T 15-10-2018 IPR023430 Peptidase HybD-like domain superfamily C2I28_20395 2eb4d00534c5423277c409109343cd5d 99 SUPERFAMILY SSF89360 2 80 1.0E-7 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_20395 2eb4d00534c5423277c409109343cd5d 99 Gene3D G3DSA:2.60.300.12 1 97 2.0E-8 T 15-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 C2I28_13935 6747c525bbf970aac3240abc78281c7a 102 Pfam PF14150 YesK-like protein 22 90 1.1E-21 T 15-10-2018 IPR025434 YesK-like protein C2I28_11060 e8b1166d731839e70b064da696f4f1d9 31 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 7 30 5.1E-13 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_11060 e8b1166d731839e70b064da696f4f1d9 31 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 28 3.3E-14 T 15-10-2018 IPR010070 Sporulation protein YjcZ-like C2I28_12920 e5f0abf9490ab3c9a486cde3e4980159 189 SUPERFAMILY SSF89957 6 186 1.14E-32 T 15-10-2018 IPR029756 MTH1187/YkoF-like C2I28_12920 e5f0abf9490ab3c9a486cde3e4980159 189 Gene3D G3DSA:3.30.70.930 107 189 1.5E-23 T 15-10-2018 IPR029756 MTH1187/YkoF-like C2I28_12920 e5f0abf9490ab3c9a486cde3e4980159 189 Gene3D G3DSA:3.30.70.930 2 81 5.0E-21 T 15-10-2018 IPR029756 MTH1187/YkoF-like C2I28_12920 e5f0abf9490ab3c9a486cde3e4980159 189 Pfam PF07615 YKOF-related Family 6 80 3.0E-21 T 15-10-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative C2I28_12920 e5f0abf9490ab3c9a486cde3e4980159 189 Pfam PF07615 YKOF-related Family 110 186 2.1E-19 T 15-10-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative C2I28_26075 56ae70e52f332270b9d6a192bfe70cfb 196 Gene3D G3DSA:3.40.630.30 1 143 5.8E-17 T 15-10-2018 C2I28_26075 56ae70e52f332270b9d6a192bfe70cfb 196 SUPERFAMILY SSF55729 3 145 2.7E-19 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_26075 56ae70e52f332270b9d6a192bfe70cfb 196 Pfam PF13508 Acetyltransferase (GNAT) domain 45 134 7.6E-9 T 15-10-2018 IPR000182 GNAT domain C2I28_27365 c4cc0fbef066eec0fe6175ae477485ed 351 Pfam PF02958 Ecdysteroid kinase 90 260 3.4E-8 T 15-10-2018 IPR004119 Protein of unknown function DUF227 C2I28_27365 c4cc0fbef066eec0fe6175ae477485ed 351 SUPERFAMILY SSF56112 46 297 3.21E-19 T 15-10-2018 IPR011009 Protein kinase-like domain superfamily C2I28_27365 c4cc0fbef066eec0fe6175ae477485ed 351 Gene3D G3DSA:3.90.1200.10 94 299 1.1E-5 T 15-10-2018 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 Gene3D G3DSA:3.50.50.60 121 240 9.3E-75 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.4E-30 T 15-10-2018 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.4E-30 T 15-10-2018 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.4E-30 T 15-10-2018 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.4E-30 T 15-10-2018 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.4E-30 T 15-10-2018 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 Gene3D G3DSA:3.50.50.60 5 299 9.3E-75 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 2.2E-44 T 15-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 287 306 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 1.1E-31 T 15-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 C2I28_13560 2d2115f83fe3b1040eb2595a1f283046 309 SUPERFAMILY SSF51905 1 304 2.83E-45 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_22000 573016219c72e1fcad9e73c46ce6cc43 422 Pfam PF02447 GntP family permease 11 416 1.1E-17 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 245 31.699 T 15-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 PRINTS PR01900 YidC translocation/secretion protein signature 43 59 7.5E-9 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 PRINTS PR01900 YidC translocation/secretion protein signature 196 220 7.5E-9 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 PRINTS PR01900 YidC translocation/secretion protein signature 174 189 7.5E-9 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 PRINTS PR00701 60kDa inner membrane protein signature 123 146 1.2E-14 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 PRINTS PR00701 60kDa inner membrane protein signature 207 230 1.2E-14 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 Pfam PF02096 60Kd inner membrane protein 58 240 2.7E-60 T 15-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 C2I28_08000 a1ba224e36418c69de196ff593356d5c 254 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 57 240 1.2E-66 T 15-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 C2I28_04785 f2e258b6415baf410239d237c8031968 219 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 16 210 4.6E-22 T 15-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like C2I28_08260 7ef6e92fed87acca8a397bece05c09ea 109 Gene3D G3DSA:3.30.70.120 1 103 2.9E-44 T 15-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal C2I28_08260 7ef6e92fed87acca8a397bece05c09ea 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 2.4E-52 T 15-10-2018 IPR010375 Cyclic-di-AMP receptor C2I28_08260 7ef6e92fed87acca8a397bece05c09ea 109 SUPERFAMILY SSF54913 1 107 3.5E-14 T 15-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta C2I28_26445 2049aeb4d43195bd0dec10cd09e46218 317 SUPERFAMILY SSF57783 5 73 4.42E-5 T 15-10-2018 C2I28_26445 2049aeb4d43195bd0dec10cd09e46218 317 Pfam PF13154 Protein of unknown function (DUF3991) 113 176 6.3E-11 T 15-10-2018 IPR025054 Domain of unknown function DUF3991 C2I28_26445 2049aeb4d43195bd0dec10cd09e46218 317 Gene3D G3DSA:3.40.1360.10 187 306 3.9E-6 T 15-10-2018 C2I28_26445 2049aeb4d43195bd0dec10cd09e46218 317 Pfam PF13155 Toprim-like 198 290 2.4E-15 T 15-10-2018 C2I28_16710 2989110e452e6e4eec37100b333310f3 144 Gene3D G3DSA:3.10.180.10 1 123 1.8E-49 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_16710 2989110e452e6e4eec37100b333310f3 144 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 2.5E-16 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_16710 2989110e452e6e4eec37100b333310f3 144 SUPERFAMILY SSF54593 1 120 1.61E-24 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_27340 ff7de19160257dc6b3539ba01074437f 94 Pfam PF13799 Domain of unknown function (DUF4183) 23 91 4.4E-18 T 15-10-2018 IPR025237 Domain of unknown function DUF4183 C2I28_03555 5c84d38390e35bbb4e621ef434431e38 75 Pfam PF14004 Protein of unknown function (DUF4227) 8 75 2.3E-31 T 15-10-2018 IPR025321 Protein of unknown function DUF4227 C2I28_02185 a36b22b4e48e541905aac2a19ce9664c 86 Gene3D G3DSA:1.10.760.20 1 82 5.9E-30 T 15-10-2018 IPR038292 YmfJ/YflH superfamily C2I28_02185 a36b22b4e48e541905aac2a19ce9664c 86 Pfam PF11588 Protein of unknown function (DUF3243) 2 80 2.0E-34 T 15-10-2018 IPR021637 Protein of unknown function DUF3243 C2I28_02185 a36b22b4e48e541905aac2a19ce9664c 86 PIRSF PIRSF004764 1 86 4.5E-28 T 15-10-2018 IPR024702 Uncharacterised conserved protein YmfJ C2I28_07820 0c44cda61de57a9efbc4efd32762428d 632 Pfam PF05787 Bacterial protein of unknown function (DUF839) 176 583 6.9E-23 T 15-10-2018 IPR008557 Protein of unknown function DUF839 C2I28_18965 9fedadc949e60ea10056b238cbd58ca7 160 Pfam PF13471 Transglutaminase-like superfamily 35 143 1.7E-19 T 15-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal C2I28_16150 75f9de93208b2a65940470764d026d30 78 Gene3D G3DSA:1.20.810.10 2 65 8.9E-7 T 15-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 C2I28_16150 75f9de93208b2a65940470764d026d30 78 Pfam PF05216 UNC-50 family 10 73 7.6E-5 T 15-10-2018 IPR007881 UNC-50 C2I28_16150 75f9de93208b2a65940470764d026d30 78 SUPERFAMILY SSF81342 3 53 4.55E-9 T 15-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 C2I28_06715 39ea54fee4e3c0377701231ce96cf4ba 213 SUPERFAMILY SSF55469 10 209 6.02E-56 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_06715 39ea54fee4e3c0377701231ce96cf4ba 213 Pfam PF00881 Nitroreductase family 15 193 4.3E-29 T 15-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 C2I28_06715 39ea54fee4e3c0377701231ce96cf4ba 213 Gene3D G3DSA:3.40.109.10 3 213 6.3E-60 T 15-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 C2I28_05530 5043c096b0c7f9c989b2e96afb7f637c 155 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 124 3.1E-28 T 15-10-2018 IPR014229 Sporulation protein YtfJ C2I28_05530 5043c096b0c7f9c989b2e96afb7f637c 155 PIRSF PIRSF021377 1 154 1.2E-63 T 15-10-2018 IPR014229 Sporulation protein YtfJ C2I28_05530 5043c096b0c7f9c989b2e96afb7f637c 155 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 134 2.3E-54 T 15-10-2018 IPR014229 Sporulation protein YtfJ C2I28_07855 44dc4da5c5d540e8cb527ad80cea6001 264 SMART SM00849 13 218 2.7E-11 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_07855 44dc4da5c5d540e8cb527ad80cea6001 264 Pfam PF12706 Beta-lactamase superfamily domain 24 218 1.9E-22 T 15-10-2018 IPR001279 Metallo-beta-lactamase C2I28_07855 44dc4da5c5d540e8cb527ad80cea6001 264 SUPERFAMILY SSF56281 1 231 3.41E-42 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_07855 44dc4da5c5d540e8cb527ad80cea6001 264 Gene3D G3DSA:3.60.15.10 8 249 6.2E-42 T 15-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like C2I28_13910 2dbe46f472372b9cd0d4461f083afcc0 276 Gene3D G3DSA:1.10.260.150 39 274 5.7E-31 T 15-10-2018 C2I28_13910 2dbe46f472372b9cd0d4461f083afcc0 276 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 93 203 3.8E-17 T 15-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain C2I28_18475 b11b4f26778a697ce75c437c9c13d665 117 Pfam PF08863 YolD-like protein 15 106 1.7E-11 T 15-10-2018 IPR014962 YolD-like protein C2I28_05700 24c17d2a4c74053f9e2043e7582c2e5d 174 Pfam PF01931 Protein of unknown function DUF84 6 160 4.9E-46 T 15-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 C2I28_05700 24c17d2a4c74053f9e2043e7582c2e5d 174 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 168 26.158 T 15-10-2018 IPR002786 Non-canonical purine NTP phosphatase C2I28_05700 24c17d2a4c74053f9e2043e7582c2e5d 174 SUPERFAMILY SSF52972 1 165 8.72E-46 T 15-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I28_05700 24c17d2a4c74053f9e2043e7582c2e5d 174 Gene3D G3DSA:3.90.950.10 1 165 5.0E-51 T 15-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like C2I28_27650 28025889e5890ca542405ff144162690 282 SUPERFAMILY SSF56300 29 265 6.72E-14 T 15-10-2018 C2I28_19805 e7b2baafa6c622e94dd8de60cf679770 372 Gene3D G3DSA:3.30.9.10 88 311 1.8E-79 T 15-10-2018 C2I28_19805 e7b2baafa6c622e94dd8de60cf679770 372 Gene3D G3DSA:3.50.50.60 5 351 1.8E-79 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_19805 e7b2baafa6c622e94dd8de60cf679770 372 SUPERFAMILY SSF51905 2 367 1.94E-43 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_19805 e7b2baafa6c622e94dd8de60cf679770 372 Pfam PF01266 FAD dependent oxidoreductase 4 351 1.5E-52 T 15-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 C2I28_19805 e7b2baafa6c622e94dd8de60cf679770 372 SUPERFAMILY SSF54373 225 311 3.4E-15 T 15-10-2018 C2I28_01545 0f78b260f0fcf4a5a100be3fc85abfcd 180 Gene3D G3DSA:1.10.40.40 15 64 8.1E-36 T 15-10-2018 C2I28_01545 0f78b260f0fcf4a5a100be3fc85abfcd 180 SUPERFAMILY SSF56784 2 175 1.09E-29 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_01545 0f78b260f0fcf4a5a100be3fc85abfcd 180 Gene3D G3DSA:3.40.50.1000 5 166 8.1E-36 T 15-10-2018 IPR023214 HAD superfamily C2I28_01545 0f78b260f0fcf4a5a100be3fc85abfcd 180 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 4 173 1.6E-47 T 15-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 C2I28_05300 7cb1eb49e975c66283f65377ab66636f 86 Pfam PF06961 Protein of unknown function (DUF1294) 13 67 9.9E-24 T 15-10-2018 IPR010718 Protein of unknown function DUF1294 C2I28_05300 7cb1eb49e975c66283f65377ab66636f 86 PIRSF PIRSF002599 2 85 1.2E-10 T 15-10-2018 IPR012156 Cold shock, CspA GO:0003676 C2I28_09075 837b2fdfec1dae40912635e075144596 370 Pfam PF01757 Acyltransferase family 13 339 6.9E-30 T 15-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I28_22470 ff5d2d509bb6aedc3880a21066eeba9a 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 249 3.1E-57 T 15-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 C2I28_22470 ff5d2d509bb6aedc3880a21066eeba9a 258 SUPERFAMILY SSF56529 47 252 5.63E-66 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_22470 ff5d2d509bb6aedc3880a21066eeba9a 258 Pfam PF10370 Domain of unknown function (DUF2437) 1 50 3.9E-14 T 15-10-2018 IPR018833 Domain of unknown function DUF2437 C2I28_22470 ff5d2d509bb6aedc3880a21066eeba9a 258 Gene3D G3DSA:3.90.850.10 52 254 1.6E-68 T 15-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 C2I28_05765 41d2bd78d71aee43feeda8a18e2fd128 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 53 5.5E-9 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_05765 41d2bd78d71aee43feeda8a18e2fd128 73 SUPERFAMILY SSF46785 11 61 2.64E-8 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_05765 41d2bd78d71aee43feeda8a18e2fd128 73 SMART SM00420 11 56 0.0039 T 15-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 C2I28_05765 41d2bd78d71aee43feeda8a18e2fd128 73 Gene3D G3DSA:1.10.10.10 10 72 1.9E-7 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_17425 52622c7452046aa86361fa9b466370b5 64 Pfam PF02416 mttA/Hcf106 family 3 51 1.4E-17 T 15-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 C2I28_04915 50e4ac2a51629028231dda0b611a14f0 251 Pfam PF01478 Type IV leader peptidase family 104 205 1.9E-14 T 15-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 C2I28_04915 50e4ac2a51629028231dda0b611a14f0 251 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 11 92 5.0E-27 T 15-10-2018 IPR010627 Peptidase A24A, N-terminal C2I28_16610 794140fc0f0729fd6471634d05c8b827 143 SMART SM00387 41 141 3.5E-6 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_16610 794140fc0f0729fd6471634d05c8b827 143 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 134 4.4E-8 T 15-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase C2I28_16610 794140fc0f0729fd6471634d05c8b827 143 SUPERFAMILY SSF55874 38 134 2.19E-12 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_16610 794140fc0f0729fd6471634d05c8b827 143 Gene3D G3DSA:3.30.565.10 12 142 2.5E-14 T 15-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily C2I28_14210 a07e5d0c8930a80ea1021ea1ca8f75a1 199 TIGRFAM TIGR02132 phaR_Bmeg: polyhydroxyalkanoic acid synthase, PhaR subunit 1 189 3.1E-112 T 15-10-2018 IPR011729 Polyhydroxyalkanoic acid synthase, PhaR subunit C2I28_24320 5209b7e564475ed3200253df8a75ef90 257 Pfam PF10947 Protein of unknown function (DUF2628) 29 110 7.6E-15 T 15-10-2018 IPR024399 Protein of unknown function DUF2628 C2I28_01375 e609995142d6bf24f9ee9740270a2551 220 Pfam PF02308 MgtC family 9 134 1.9E-37 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_01375 e609995142d6bf24f9ee9740270a2551 220 PRINTS PR01837 MgtC/SapB protein signature 65 87 6.8E-46 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_01375 e609995142d6bf24f9ee9740270a2551 220 PRINTS PR01837 MgtC/SapB protein signature 12 31 6.8E-46 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_01375 e609995142d6bf24f9ee9740270a2551 220 PRINTS PR01837 MgtC/SapB protein signature 92 116 6.8E-46 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_01375 e609995142d6bf24f9ee9740270a2551 220 PRINTS PR01837 MgtC/SapB protein signature 31 49 6.8E-46 T 15-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 C2I28_25460 1bbdc0575076222242fd6e8629b2fb9e 166 Pfam PF00583 Acetyltransferase (GNAT) family 44 137 6.8E-16 T 15-10-2018 IPR000182 GNAT domain C2I28_25460 1bbdc0575076222242fd6e8629b2fb9e 166 Gene3D G3DSA:3.40.630.30 1 165 2.1E-39 T 15-10-2018 C2I28_25460 1bbdc0575076222242fd6e8629b2fb9e 166 SUPERFAMILY SSF55729 1 151 4.39E-27 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_11030 80fb96b29e53c893963981ca3f112ce7 417 Pfam PF12698 ABC-2 family transporter protein 19 386 1.4E-55 T 15-10-2018 C2I28_17415 241f74c13179bb9a730724a68e353121 116 SUPERFAMILY SSF54593 9 115 1.61E-16 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_17415 241f74c13179bb9a730724a68e353121 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 111 2.4E-9 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_17415 241f74c13179bb9a730724a68e353121 116 Gene3D G3DSA:3.10.180.10 2 115 2.7E-16 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_23145 682565909f7976428b18037c67eb51ed 152 Pfam PF00583 Acetyltransferase (GNAT) family 34 138 1.9E-10 T 15-10-2018 IPR000182 GNAT domain C2I28_23145 682565909f7976428b18037c67eb51ed 152 Gene3D G3DSA:3.40.630.30 2 152 3.3E-30 T 15-10-2018 C2I28_23145 682565909f7976428b18037c67eb51ed 152 SUPERFAMILY SSF55729 2 148 5.32E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_19010 70c2c7af6b9e5cd272421e9908263df5 313 Gene3D G3DSA:3.60.21.10 50 249 1.0E-17 T 15-10-2018 IPR029052 Metallo-dependent phosphatase-like C2I28_19010 70c2c7af6b9e5cd272421e9908263df5 313 Pfam PF00149 Calcineurin-like phosphoesterase 51 235 1.3E-7 T 15-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 C2I28_19010 70c2c7af6b9e5cd272421e9908263df5 313 SUPERFAMILY SSF56300 45 287 1.19E-18 T 15-10-2018 C2I28_23840 0d07caa30da1e87ebba5c6e0334457c7 263 Pfam PF01925 Sulfite exporter TauE/SafE 10 252 2.6E-36 T 15-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 C2I28_04575 b91419c22eacbf5b88114516e871a38c 309 Pfam PF01136 Peptidase family U32 75 306 4.1E-67 T 15-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 C2I28_19810 d16533e604eef1eff3338f4a8995f01d 104 ProDom PD673109 PRECURSOR SIGNAL YCKD ORF4 DOMAIN 1 100 6.0E-16 T 15-10-2018 IPR024485 Protein of unknown function DUF2680 C2I28_19810 d16533e604eef1eff3338f4a8995f01d 104 Pfam PF10925 Protein of unknown function (DUF2680) 35 91 1.4E-19 T 15-10-2018 IPR024485 Protein of unknown function DUF2680 C2I28_00960 faef79460b91a6be8b4aa152614d35bc 196 Pfam PF02517 CAAX protease self-immunity 96 187 1.4E-16 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_10835 9e120fda4d3fca99758490df9d76eef8 83 Pfam PF14148 YhdB-like protein 1 70 7.0E-40 T 15-10-2018 IPR025431 YhdB-like protein C2I28_03410 e2c4e00834f64a4b75acb43f50c3e209 392 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 49 392 2.8E-75 T 15-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 C2I28_03410 e2c4e00834f64a4b75acb43f50c3e209 392 Pfam PF01578 Cytochrome C assembly protein 290 389 4.9E-23 T 15-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 C2I28_03410 e2c4e00834f64a4b75acb43f50c3e209 392 Pfam PF01578 Cytochrome C assembly protein 73 195 1.5E-8 T 15-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 C2I28_14500 18084d637e5de4d84ac2dd8b649d7f98 265 Gene3D G3DSA:3.30.1240.10 82 188 3.6E-57 T 15-10-2018 C2I28_14500 18084d637e5de4d84ac2dd8b649d7f98 265 Gene3D G3DSA:3.40.50.1000 5 252 3.6E-57 T 15-10-2018 IPR023214 HAD superfamily C2I28_14500 18084d637e5de4d84ac2dd8b649d7f98 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 252 3.2E-51 T 15-10-2018 C2I28_14500 18084d637e5de4d84ac2dd8b649d7f98 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 232 8.7E-30 T 15-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 C2I28_14500 18084d637e5de4d84ac2dd8b649d7f98 265 SUPERFAMILY SSF56784 1 252 1.77E-58 T 15-10-2018 IPR036412 HAD-like superfamily C2I28_14500 18084d637e5de4d84ac2dd8b649d7f98 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 1.1E-50 T 15-10-2018 IPR000150 Cof family GO:0016787 C2I28_17345 635a39a7259ada2901c0e3cf3ce5ec0a 458 PIRSF PIRSF005353 15 458 8.5E-169 T 15-10-2018 IPR026033 Purine permease PbuG-like C2I28_17345 635a39a7259ada2901c0e3cf3ce5ec0a 458 Pfam PF00860 Permease family 41 415 7.0E-52 T 15-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 Pfam PF07690 Major Facilitator Superfamily 8 223 1.5E-35 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 PRINTS PR01035 Tetracycline resistance protein signature 14 30 8.8E-24 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 PRINTS PR01035 Tetracycline resistance protein signature 158 178 8.8E-24 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 PRINTS PR01035 Tetracycline resistance protein signature 329 352 8.8E-24 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 PRINTS PR01035 Tetracycline resistance protein signature 130 152 8.8E-24 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 PRINTS PR01035 Tetracycline resistance protein signature 269 290 8.8E-24 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 PRINTS PR01035 Tetracycline resistance protein signature 71 95 8.8E-24 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 Gene3D G3DSA:1.20.1250.20 2 377 1.8E-64 T 15-10-2018 C2I28_14100 7a45064bfb13d46a3c215709b387076f 389 SUPERFAMILY SSF103473 3 374 8.37E-61 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_12140 4da308eb58ddfc9433d6c59b6b6650ab 122 Pfam PF01638 HxlR-like helix-turn-helix 14 102 9.3E-37 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_12140 4da308eb58ddfc9433d6c59b6b6650ab 122 Gene3D G3DSA:1.10.10.10 1 121 4.7E-39 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_12140 4da308eb58ddfc9433d6c59b6b6650ab 122 SUPERFAMILY SSF46785 3 111 1.53E-33 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_12985 7eb20d3826bde5749de7a3c06e8154e8 209 Pfam PF07799 Protein of unknown function (DUF1643) 15 145 4.1E-20 T 15-10-2018 IPR012441 Protein of unknown function DUF1643 C2I28_10540 29a45b405df5ec60ec70391fde912aa8 253 SUPERFAMILY SSF55166 81 233 3.4E-35 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_10540 29a45b405df5ec60ec70391fde912aa8 253 Gene3D G3DSA:3.30.1380.10 35 248 2.0E-77 T 15-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 C2I28_10540 29a45b405df5ec60ec70391fde912aa8 253 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 96 225 6.2E-43 T 15-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 C2I28_02115 59c03c2de79803de5596c2b0a93cdb1f 181 Pfam PF10628 Outer spore coat protein E (CotE) 5 176 1.7E-74 T 15-10-2018 IPR018901 Spore coat protein CotE C2I28_03795 f666a9a5b43180b1ee47063204bc0c71 242 Gene3D G3DSA:3.20.20.190 1 238 5.0E-79 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_03795 f666a9a5b43180b1ee47063204bc0c71 242 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 231 7.7E-45 T 15-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 C2I28_03795 f666a9a5b43180b1ee47063204bc0c71 242 SUPERFAMILY SSF51695 1 235 5.65E-70 T 15-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 C2I28_11100 2db2a0eca8ca5905598c88ca759e3888 147 Pfam PF13673 Acetyltransferase (GNAT) domain 45 146 2.2E-15 T 15-10-2018 IPR000182 GNAT domain C2I28_11100 2db2a0eca8ca5905598c88ca759e3888 147 Gene3D G3DSA:3.40.630.30 1 146 1.2E-40 T 15-10-2018 C2I28_11100 2db2a0eca8ca5905598c88ca759e3888 147 SUPERFAMILY SSF55729 1 146 2.13E-30 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_04570 0c517e2ca69497f75d3226d4015bffdd 420 Pfam PF16325 Peptidase family U32 C-terminal domain 337 417 2.0E-24 T 15-10-2018 IPR032525 Peptidase family U32, C-terminal C2I28_04570 0c517e2ca69497f75d3226d4015bffdd 420 Pfam PF01136 Peptidase family U32 90 321 4.7E-86 T 15-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 C2I28_04570 0c517e2ca69497f75d3226d4015bffdd 420 Gene3D G3DSA:2.40.30.10 332 419 1.7E-36 T 15-10-2018 C2I28_04570 0c517e2ca69497f75d3226d4015bffdd 420 ProSitePatterns PS01276 Peptidase family U32 signature. 176 194 - T 15-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 C2I28_19990 d3ccc21ddfbd2ca468d1a8621215bef6 186 SUPERFAMILY SSF53850 20 171 2.06E-5 T 15-10-2018 C2I28_20910 abb0bb524ccd4f047eb9b1cd9811df45 46 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 46 16.119 T 15-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 C2I28_20910 abb0bb524ccd4f047eb9b1cd9811df45 46 Pfam PF08179 Small acid-soluble spore protein P family 1 41 7.4E-19 T 15-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 C2I28_19335 12fef8dd746564151895f73dfcd6cff8 184 Pfam PF11553 Protein of unknown function (DUF3231) 42 177 1.5E-22 T 15-10-2018 IPR021617 Protein of unknown function DUF3231 C2I28_19335 12fef8dd746564151895f73dfcd6cff8 184 Gene3D G3DSA:1.20.1260.10 15 167 7.0E-52 T 15-10-2018 IPR012347 Ferritin-like C2I28_23835 fe8e6773bf26ea6b809f376442eaa7df 241 SUPERFAMILY SSF63817 102 237 7.72E-37 T 15-10-2018 IPR023365 Sortase domain superfamily C2I28_23835 fe8e6773bf26ea6b809f376442eaa7df 241 TIGRFAM TIGR01076 sortase_fam: sortase 113 237 1.3E-30 T 15-10-2018 IPR005754 Sortase family C2I28_23835 fe8e6773bf26ea6b809f376442eaa7df 241 Gene3D G3DSA:2.40.260.10 48 241 1.3E-45 T 15-10-2018 IPR023365 Sortase domain superfamily C2I28_23835 fe8e6773bf26ea6b809f376442eaa7df 241 Pfam PF04203 Sortase family 115 236 4.6E-29 T 15-10-2018 IPR005754 Sortase family C2I28_24120 fe4f989870acebc6277246ed766ab0f2 274 SUPERFAMILY SSF102114 26 198 4.84E-9 T 15-10-2018 C2I28_24120 fe4f989870acebc6277246ed766ab0f2 274 Pfam PF04055 Radical SAM superfamily 28 194 1.1E-7 T 15-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 C2I28_09650 db9c8a7e378e0576da45bec8565c227f 425 Pfam PF04286 Protein of unknown function (DUF445) 50 423 4.1E-82 T 15-10-2018 IPR007383 Protein of unknown function DUF445 C2I28_14800 4587787637a73b9697c5d0c5c876752d 41 Pfam PF13790 SR1 protein 1 37 4.1E-22 T 15-10-2018 IPR025236 SR1 protein C2I28_16060 4bd38362cb40ad128eb6811aecb67c85 248 Pfam PF01048 Phosphorylase superfamily 74 215 8.9E-15 T 15-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 C2I28_16060 4bd38362cb40ad128eb6811aecb67c85 248 SUPERFAMILY SSF53167 16 244 1.57E-37 T 15-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 C2I28_16060 4bd38362cb40ad128eb6811aecb67c85 248 Gene3D G3DSA:3.40.50.1580 16 245 6.7E-32 T 15-10-2018 C2I28_15315 4391d587276d46246db4bfeb63772108 257 Pfam PF10127 Predicted nucleotidyltransferase 1 246 4.1E-47 T 15-10-2018 IPR018775 Nucleotidyltransferase, predicted C2I28_01870 2f3ba848159bdeb952610d7a85bf91ca 601 Gene3D G3DSA:1.10.274.90 2 134 2.7E-20 T 15-10-2018 C2I28_01870 2f3ba848159bdeb952610d7a85bf91ca 601 Pfam PF06276 Ferric iron reductase FhuF-like transporter 414 573 1.2E-41 T 15-10-2018 IPR022770 Ferric iron reductase FhuF domain C2I28_01870 2f3ba848159bdeb952610d7a85bf91ca 601 Gene3D G3DSA:1.10.510.40 381 582 9.6E-61 T 15-10-2018 C2I28_01870 2f3ba848159bdeb952610d7a85bf91ca 601 Pfam PF04183 IucA / IucC family 142 392 6.2E-73 T 15-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 C2I28_17600 6914312a51bd36a4ef18a03e4a5962b8 505 SUPERFAMILY SSF53474 138 474 3.86E-13 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_19130 0606a720dcede26a60fe13e687eadb2f 436 Pfam PF03553 Na+/H+ antiporter family 71 211 8.4E-13 T 15-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I28_19130 0606a720dcede26a60fe13e687eadb2f 436 Pfam PF03553 Na+/H+ antiporter family 224 421 3.8E-13 T 15-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I28_12285 afe6a87517efcfe1497f9b51a3825b53 398 Pfam PF02687 FtsX-like permease family 304 391 2.4E-12 T 15-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 C2I28_12285 afe6a87517efcfe1497f9b51a3825b53 398 Pfam PF12704 MacB-like periplasmic core domain 21 241 7.2E-32 T 15-10-2018 IPR025857 MacB-like periplasmic core domain C2I28_02000 94c683ea22da0a5e95cc248638151055 76 Gene3D G3DSA:1.10.287.540 1 58 3.8E-23 T 15-10-2018 C2I28_02000 94c683ea22da0a5e95cc248638151055 76 SUPERFAMILY SSF158221 1 42 3.14E-14 T 15-10-2018 C2I28_02000 94c683ea22da0a5e95cc248638151055 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 8.3E-31 T 15-10-2018 IPR009242 Protein of unknown function DUF896 C2I28_02000 94c683ea22da0a5e95cc248638151055 76 Hamap MF_01103 UPF0291 protein . 2 60 16.216 T 15-10-2018 IPR009242 Protein of unknown function DUF896 C2I28_24720 ac52c6e537144bb63048b6a0c804130a 205 Pfam PF01810 LysE type translocator 12 201 2.5E-38 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_24720 ac52c6e537144bb63048b6a0c804130a 205 PIRSF PIRSF006324 1 204 1.2E-60 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_12125 ddba544d53827c1af02ae7e4396de2fb 54 SUPERFAMILY SSF140500 1 52 4.19E-8 T 15-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 C2I28_12125 ddba544d53827c1af02ae7e4396de2fb 54 Pfam PF09388 Spo0E like sporulation regulatory protein 6 48 2.8E-11 T 15-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 C2I28_21425 02a18af98e6504d7857d884d0743551e 137 Pfam PF13673 Acetyltransferase (GNAT) domain 42 128 5.2E-15 T 15-10-2018 IPR000182 GNAT domain C2I28_21425 02a18af98e6504d7857d884d0743551e 137 SUPERFAMILY SSF55729 13 128 7.69E-25 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_21425 02a18af98e6504d7857d884d0743551e 137 Gene3D G3DSA:3.40.630.30 3 136 1.2E-33 T 15-10-2018 C2I28_14050 ee5d03152edefaee1ef4087b094c75a4 111 Pfam PF06305 Lipopolysaccharide assembly protein A domain 24 86 6.2E-17 T 15-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 C2I28_14155 0bc5d8ab770da0df953cfb4fc89e9fe1 374 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 11 360 1.6E-46 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_14155 0bc5d8ab770da0df953cfb4fc89e9fe1 374 Pfam PF03845 Spore germination protein 10 321 2.3E-75 T 15-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 C2I28_15565 de385055f8a9d4ec51cb4449ec59cd0a 123 Pfam PF04134 Protein of unknown function, DUF393 5 116 1.0E-20 T 15-10-2018 IPR007263 Protein of unknown function DUF393 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 PRINTS PR01035 Tetracycline resistance protein signature 276 296 4.6E-7 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 PRINTS PR01035 Tetracycline resistance protein signature 43 59 4.6E-7 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 PRINTS PR01035 Tetracycline resistance protein signature 162 184 4.6E-7 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 PRINTS PR01035 Tetracycline resistance protein signature 132 153 4.6E-7 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 SUPERFAMILY SSF103473 26 418 7.85E-75 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 Pfam PF07690 Major Facilitator Superfamily 38 318 3.6E-41 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 Gene3D G3DSA:1.20.1250.20 231 423 1.5E-30 T 15-10-2018 C2I28_21085 e6cbba5992743d501cc23520a7905e51 425 Gene3D G3DSA:1.20.1250.20 27 230 6.1E-43 T 15-10-2018 C2I28_19225 159e4ec34e048c65e71a1ecd717918aa 466 Pfam PF03553 Na+/H+ antiporter family 154 462 1.9E-34 T 15-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 C2I28_09030 c2385e3267ed8d13728a5330fbc6a7ca 161 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 147 7.7E-14 T 15-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain C2I28_09030 c2385e3267ed8d13728a5330fbc6a7ca 161 Gene3D G3DSA:3.10.180.10 1 154 6.4E-24 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_09030 c2385e3267ed8d13728a5330fbc6a7ca 161 SUPERFAMILY SSF54593 3 152 2.42E-22 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_00605 72ffa5532a64eee7108304be56cb6b70 194 Pfam PF14172 Domain of unknown function (DUF4309) 54 190 1.4E-30 T 15-10-2018 IPR025453 Protein of unknown function DUF4309 C2I28_06540 90d863df033df48990a70755ff5a0b7f 127 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 51 100 4.0E-8 T 15-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_06540 90d863df033df48990a70755ff5a0b7f 127 Gene3D G3DSA:1.20.1290.10 5 123 1.0E-28 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_06540 90d863df033df48990a70755ff5a0b7f 127 SUPERFAMILY SSF69118 7 122 6.02E-27 T 15-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 C2I28_06540 90d863df033df48990a70755ff5a0b7f 127 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 116 5.6E-20 T 15-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 C2I28_03250 fd60b832f21ad89482b6474124476765 240 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 14 237 1.0E-83 T 15-10-2018 C2I28_25455 0919c0bc95edda3d623afb8af1273bae 309 SUPERFAMILY SSF46785 64 172 6.82E-5 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18240 2e506e67d021d059fb699ff6e4485104 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 15-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 C2I28_18240 2e506e67d021d059fb699ff6e4485104 312 Pfam PF00294 pfkB family carbohydrate kinase 4 301 2.9E-47 T 15-10-2018 IPR011611 Carbohydrate kinase PfkB C2I28_18240 2e506e67d021d059fb699ff6e4485104 312 SUPERFAMILY SSF53613 3 305 2.18E-61 T 15-10-2018 IPR029056 Ribokinase-like C2I28_18240 2e506e67d021d059fb699ff6e4485104 312 Gene3D G3DSA:3.40.1190.20 1 308 1.2E-66 T 15-10-2018 IPR029056 Ribokinase-like C2I28_17545 d98cba92650e1011f46fa1b4bd1243b2 330 Pfam PF07907 YibE/F-like protein 88 319 7.3E-75 T 15-10-2018 IPR012507 YibE/F-like C2I28_24650 6e68c49ac4475e71d5ca539a9f852d26 178 Gene3D G3DSA:2.60.120.40 33 173 2.0E-9 T 15-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I28_24650 6e68c49ac4475e71d5ca539a9f852d26 178 SUPERFAMILY SSF49842 36 170 9.32E-17 T 15-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 C2I28_14795 70d15238a1e2c92aea9354667b86f4b7 506 ProSitePatterns PS01303 BCCT family of transporters signature. 313 322 - T 15-10-2018 IPR018093 BCCT transporter, conserved site C2I28_14795 70d15238a1e2c92aea9354667b86f4b7 506 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 496 2.8E-169 T 15-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I28_14795 70d15238a1e2c92aea9354667b86f4b7 506 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 496 1.2E-195 T 15-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 C2I28_22580 9ed875fbf1ed280fa72c536c7e5829c3 356 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 349 3.2E-166 T 15-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 C2I28_22580 9ed875fbf1ed280fa72c536c7e5829c3 356 SUPERFAMILY SSF51679 1 351 5.63E-94 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_22580 9ed875fbf1ed280fa72c536c7e5829c3 356 Gene3D G3DSA:3.20.20.30 1 356 1.0E-138 T 15-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 C2I28_22580 9ed875fbf1ed280fa72c536c7e5829c3 356 Pfam PF00296 Luciferase-like monooxygenase 1 325 1.3E-86 T 15-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 C2I28_15205 5247177b5da3cd748934904dff3200e4 242 PIRSF PIRSF031509 4 242 1.8E-63 T 15-10-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 C2I28_15205 5247177b5da3cd748934904dff3200e4 242 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 127 239 1.1E-36 T 15-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF C2I28_12650 df0fca1cba58d04f030ab2ecd7a67279 107 Pfam PF11588 Protein of unknown function (DUF3243) 30 106 6.6E-27 T 15-10-2018 IPR021637 Protein of unknown function DUF3243 C2I28_12650 df0fca1cba58d04f030ab2ecd7a67279 107 Gene3D G3DSA:1.10.760.20 25 107 1.4E-29 T 15-10-2018 IPR038292 YmfJ/YflH superfamily C2I28_13080 99ed15fafc708e2c5fd76768b49e9a1a 147 Gene3D G3DSA:3.40.30.10 1 146 1.2E-34 T 15-10-2018 C2I28_13080 99ed15fafc708e2c5fd76768b49e9a1a 147 SUPERFAMILY SSF52833 2 142 1.45E-30 T 15-10-2018 IPR036249 Thioredoxin-like superfamily C2I28_13080 99ed15fafc708e2c5fd76768b49e9a1a 147 Pfam PF00578 AhpC/TSA family 5 125 3.0E-12 T 15-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 C2I28_10730 0a40e6d4905cadf8b70b5e07ff6d6924 380 Pfam PF01594 AI-2E family transporter 40 364 8.9E-87 T 15-10-2018 IPR002549 Transmembrane protein TqsA-like C2I28_07605 b9b34fe848d14c12d14ab81b0b5983f6 123 Pfam PF04241 Protein of unknown function (DUF423) 18 105 1.6E-32 T 15-10-2018 IPR006696 Protein of unknown function DUF423 C2I28_22680 c0ed996fbac20edd3ad6835f1c543ddd 406 Pfam PF04235 Protein of unknown function (DUF418) 234 393 8.9E-34 T 15-10-2018 IPR007349 Domain of unknown function DUF418 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 Gene3D G3DSA:3.30.1490.100 258 368 4.0E-11 T 15-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 Pfam PF00817 impB/mucB/samB family 14 163 6.4E-29 T 15-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 256 365 1.5E-16 T 15-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 SUPERFAMILY SSF100879 258 357 8.24E-14 T 15-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 Gene3D G3DSA:1.10.150.20 189 242 1.9E-50 T 15-10-2018 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 Gene3D G3DSA:2.30.40.20 28 81 1.9E-50 T 15-10-2018 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 Gene3D G3DSA:3.30.70.270 11 245 1.9E-50 T 15-10-2018 C2I28_26715 e1d29f660e4b695a36fd596cfa2ebf0e 421 SUPERFAMILY SSF56672 9 249 2.13E-52 T 15-10-2018 C2I28_12375 6bd5159fbabdbbce97d9068c5057eca7 192 Pfam PF01794 Ferric reductase like transmembrane component 22 142 5.6E-10 T 15-10-2018 IPR013130 Ferric reductase transmembrane component-like domain C2I28_14065 fdbfa96916cf0df110a5bcc4eefa97ea 168 Pfam PF13673 Acetyltransferase (GNAT) domain 47 154 2.3E-9 T 15-10-2018 IPR000182 GNAT domain C2I28_14065 fdbfa96916cf0df110a5bcc4eefa97ea 168 SUPERFAMILY SSF55729 2 147 1.58E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_14065 fdbfa96916cf0df110a5bcc4eefa97ea 168 Gene3D G3DSA:3.40.630.30 1 160 4.3E-23 T 15-10-2018 C2I28_26040 c65c9c1e853439de246f937dc8b01abb 446 Pfam PF02952 L-fucose isomerase, C-terminal domain 358 441 1.0E-7 T 15-10-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 C2I28_26040 c65c9c1e853439de246f937dc8b01abb 446 SUPERFAMILY SSF53743 8 304 3.4E-38 T 15-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 C2I28_26040 c65c9c1e853439de246f937dc8b01abb 446 SUPERFAMILY SSF50443 313 442 1.8E-6 T 15-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal C2I28_02235 03e5c244cb2f695d0ac8e639544bb472 69 Pfam PF14035 YlzJ-like protein 3 68 5.5E-26 T 15-10-2018 IPR025619 YlzJ-like protein C2I28_16860 0495f78c5ed9e5019c3dfb8ef79badb9 219 Pfam PF13021 Domain of unknown function (DUF3885) 177 214 2.5E-20 T 15-10-2018 IPR024976 Domain of unknown function DUF3885 C2I28_21570 08b4d013cb269bc7afe21c536d763a9d 363 PIRSF PIRSF026508 1 361 2.8E-112 T 15-10-2018 IPR008863 Toxic anion resistance C2I28_21570 08b4d013cb269bc7afe21c536d763a9d 363 Pfam PF05816 Toxic anion resistance protein (TelA) 35 358 9.6E-103 T 15-10-2018 IPR008863 Toxic anion resistance C2I28_15000 0d2c08861e88c27977c8aa6c2ed7baca 285 SUPERFAMILY SSF52374 1 281 6.33E-101 T 15-10-2018 C2I28_15000 0d2c08861e88c27977c8aa6c2ed7baca 285 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 37.727 T 15-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 C2I28_15000 0d2c08861e88c27977c8aa6c2ed7baca 285 Pfam PF02569 Pantoate-beta-alanine ligase 2 277 4.3E-99 T 15-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 C2I28_15000 0d2c08861e88c27977c8aa6c2ed7baca 285 Gene3D G3DSA:3.30.1300.10 178 277 3.9E-32 T 15-10-2018 C2I28_15000 0d2c08861e88c27977c8aa6c2ed7baca 285 Gene3D G3DSA:3.40.50.620 1 177 8.3E-72 T 15-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold C2I28_15000 0d2c08861e88c27977c8aa6c2ed7baca 285 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 3.4E-108 T 15-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 C2I28_17500 4edaac58f4f4fa55997123a37813dbad 110 Gene3D G3DSA:1.20.58.1000 6 110 5.7E-32 T 15-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily C2I28_17500 4edaac58f4f4fa55997123a37813dbad 110 Pfam PF02583 Metal-sensitive transcriptional repressor 29 107 2.3E-29 T 15-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 C2I28_08410 bbe57c09d76d98c3f5ffa11731eda60c 207 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 2.0E-21 T 15-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like C2I28_08410 bbe57c09d76d98c3f5ffa11731eda60c 207 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 5.1E-41 T 15-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 Pfam PF07690 Major Facilitator Superfamily 8 319 7.7E-39 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 Gene3D G3DSA:1.20.1250.20 198 386 7.4E-19 T 15-10-2018 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 Gene3D G3DSA:1.20.1250.20 5 197 6.4E-29 T 15-10-2018 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 PRINTS PR01035 Tetracycline resistance protein signature 40 59 3.7E-5 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 PRINTS PR01035 Tetracycline resistance protein signature 158 178 3.7E-5 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 PRINTS PR01035 Tetracycline resistance protein signature 10 26 3.7E-5 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 PRINTS PR01035 Tetracycline resistance protein signature 98 119 3.7E-5 T 15-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 C2I28_21040 1e241b0485f2cb8c43a1ac11a91a76e1 389 SUPERFAMILY SSF103473 3 380 3.79E-56 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_03375 be9e0c00d0540bc99f6d1e66dd67dbed 349 Pfam PF14493 Helix-turn-helix domain 257 344 2.0E-25 T 15-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I28_03375 be9e0c00d0540bc99f6d1e66dd67dbed 349 PIRSF PIRSF021350 2 349 2.5E-95 T 15-10-2018 IPR008308 Uncharacterised conserved protein UCP021350 C2I28_14085 45a4e05b3d8c2c998cd6e613adc37f74 265 Gene3D G3DSA:3.10.180.10 2 160 2.0E-48 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_14085 45a4e05b3d8c2c998cd6e613adc37f74 265 Pfam PF13468 Glyoxalase-like domain 5 191 3.1E-30 T 15-10-2018 IPR025870 Glyoxalase-like domain C2I28_14085 45a4e05b3d8c2c998cd6e613adc37f74 265 SUPERFAMILY SSF54593 3 200 1.4E-7 T 15-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase C2I28_00490 4be328fa5bf63e0addee0b90fa8a7fd3 164 Pfam PF11667 Putative zincin peptidase 55 154 3.0E-17 T 15-10-2018 IPR021683 Putative zincin peptidase C2I28_12210 1d7c16de7723913a075ca8ccd7dbd04c 67 Pfam PF11755 Protein of unknown function (DUF3311) 9 64 1.5E-13 T 15-10-2018 IPR021741 Protein of unknown function DUF3311 C2I28_01815 081a6172f76814d63f611b58f2fac268 190 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 3 185 5.9E-64 T 15-10-2018 IPR018672 Protein of unknown function DUF2140 C2I28_22160 973be58ccdba7a62ce90b6949bedbe66 467 Pfam PF05076 Suppressor of fused protein (SUFU) 263 451 6.5E-20 T 15-10-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 C2I28_20575 1744142ba7069c4766c28b57e173adb5 152 Gene3D G3DSA:3.40.630.30 1 141 3.0E-19 T 15-10-2018 C2I28_20575 1744142ba7069c4766c28b57e173adb5 152 Pfam PF00583 Acetyltransferase (GNAT) family 32 132 1.4E-10 T 15-10-2018 IPR000182 GNAT domain C2I28_20575 1744142ba7069c4766c28b57e173adb5 152 SUPERFAMILY SSF55729 1 142 3.95E-20 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_26455 df4bf90ce3c9228f498bb053698bea03 136 PIRSF PIRSF021328 1 136 7.2E-49 T 15-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 C2I28_26455 df4bf90ce3c9228f498bb053698bea03 136 Pfam PF11208 Protein of unknown function (DUF2992) 3 136 2.5E-46 T 15-10-2018 IPR016787 Uncharacterised conserved protein UCP021328 C2I28_07845 fa1b6b44602f9c33281727776c87d67b 52 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 3 50 2.3E-17 T 15-10-2018 IPR025626 YyzF-like protein C2I28_07845 fa1b6b44602f9c33281727776c87d67b 52 Pfam PF14116 YyzF-like protein 5 51 8.9E-19 T 15-10-2018 IPR025626 YyzF-like protein C2I28_20825 3397089b3b6427bf8f49c7f64a6982dd 255 Pfam PF08892 YqcI/YcgG family 33 241 7.0E-79 T 15-10-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG C2I28_09850 3afce2b61a3a05006d517c33273de3c8 384 Pfam PF04231 Endonuclease I 167 377 7.8E-47 T 15-10-2018 IPR007346 Endonuclease I GO:0004518 C2I28_09850 3afce2b61a3a05006d517c33273de3c8 384 SUPERFAMILY SSF54060 164 377 5.41E-61 T 15-10-2018 C2I28_17140 0e2f8a6d25b2c3ecb78522889ba91729 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 379 4.4E-111 T 15-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 C2I28_17140 0e2f8a6d25b2c3ecb78522889ba91729 388 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 176 204 - T 15-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 C2I28_17140 0e2f8a6d25b2c3ecb78522889ba91729 388 Gene3D G3DSA:3.40.50.1970 1 187 3.0E-53 T 15-10-2018 C2I28_17140 0e2f8a6d25b2c3ecb78522889ba91729 388 Gene3D G3DSA:1.20.1090.10 189 386 5.6E-64 T 15-10-2018 C2I28_17140 0e2f8a6d25b2c3ecb78522889ba91729 388 SUPERFAMILY SSF56796 5 385 2.09E-118 T 15-10-2018 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 208 56.817 T 15-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 184 3.2E-62 T 15-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 SUPERFAMILY SSF53850 2 207 3.69E-66 T 15-10-2018 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 Gene3D G3DSA:3.40.190.10 95 176 7.9E-80 T 15-10-2018 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 Pfam PF01634 ATP phosphoribosyltransferase 54 204 9.7E-51 T 15-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 15-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 C2I28_06930 599d8d54098dd856575cec05bc7fda8a 210 Gene3D G3DSA:3.40.190.10 6 199 7.9E-80 T 15-10-2018 C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 2.4E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.4E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.4E-12 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 SMART SM00418 14 93 4.4E-21 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 SUPERFAMILY SSF46785 13 93 2.47E-22 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 Gene3D G3DSA:1.10.10.10 2 98 3.2E-24 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_18525 5275134c6e286e28e78f817ceedf2461 100 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 1.2E-13 T 15-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 C2I28_27005 406bcbc374e9921abe78bcc8229c9c57 122 Pfam PF17428 Family of unknown function (DUF5412) 2 120 1.1E-41 T 15-10-2018 IPR035406 Protein of unknown function DUF5412 C2I28_02725 5b53d6703fdc959fd292f590bd16229f 26 Pfam PF08183 Stage V sporulation protein family 1 25 5.4E-17 T 15-10-2018 IPR012609 Sporulation stage V, protein M C2I28_08525 9a6c2925a101b3bcb3557968ac2072fe 153 Gene3D G3DSA:1.10.10.1240 2 72 6.7E-36 T 15-10-2018 C2I28_08525 9a6c2925a101b3bcb3557968ac2072fe 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 1.1E-58 T 15-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 C2I28_08525 9a6c2925a101b3bcb3557968ac2072fe 153 PIRSF PIRSF010607 1 153 6.2E-66 T 15-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 C2I28_08525 9a6c2925a101b3bcb3557968ac2072fe 153 Gene3D G3DSA:1.10.1200.150 73 153 3.7E-30 T 15-10-2018 C2I28_17785 2f14582727a87fcd7d55dcd3684657f9 319 Pfam PF01497 Periplasmic binding protein 65 286 7.9E-41 T 15-10-2018 IPR002491 ABC transporter periplasmic binding domain C2I28_17785 2f14582727a87fcd7d55dcd3684657f9 319 SUPERFAMILY SSF53807 41 314 3.14E-67 T 15-10-2018 C2I28_17785 2f14582727a87fcd7d55dcd3684657f9 319 Gene3D G3DSA:3.40.50.1980 186 315 1.6E-41 T 15-10-2018 C2I28_17785 2f14582727a87fcd7d55dcd3684657f9 319 Gene3D G3DSA:3.40.50.1980 24 181 3.7E-39 T 15-10-2018 C2I28_24400 db6bdac0b248ec42954dfac8395bba2d 269 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 5 266 5.9E-53 T 15-10-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 C2I28_14665 47ec8784921f2e3a658990a785f841aa 160 Pfam PF13158 Protein of unknown function (DUF3993) 6 121 2.7E-15 T 15-10-2018 IPR025056 Protein of unknown function DUF3993 C2I28_00880 53941ee708f83e6ef95d1d0c5d0d666d 157 Pfam PF12732 YtxH-like protein 22 99 2.3E-17 T 15-10-2018 IPR024623 Uncharacterised protein family YtxH C2I28_09420 7470729eb82d738ace2e463cbc3df012 66 Pfam PF14044 NETI protein 10 64 4.2E-30 T 15-10-2018 IPR025930 NETI protein C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 Pfam PF07690 Major Facilitator Superfamily 12 296 7.2E-45 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 Gene3D G3DSA:1.20.1250.20 241 442 1.8E-21 T 15-10-2018 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 Gene3D G3DSA:1.20.1720.10 7 237 8.6E-48 T 15-10-2018 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 SUPERFAMILY SSF103473 4 436 2.49E-69 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 217 235 3.3E-6 T 15-10-2018 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 3.3E-6 T 15-10-2018 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 100 120 3.3E-6 T 15-10-2018 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 PRINTS PR01036 Tetracycline resistance protein TetB signature 384 403 3.3E-6 T 15-10-2018 C2I28_13500 7eb2c708b0644320224ee06c76de49e7 445 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 76 - T 15-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 C2I28_12415 3057e566195d8f91cab47cf308061c4f 156 Pfam PF00583 Acetyltransferase (GNAT) family 27 138 4.9E-10 T 15-10-2018 IPR000182 GNAT domain C2I28_12415 3057e566195d8f91cab47cf308061c4f 156 SUPERFAMILY SSF55729 4 142 1.48E-28 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_12415 3057e566195d8f91cab47cf308061c4f 156 Gene3D G3DSA:3.40.630.30 3 156 1.0E-30 T 15-10-2018 C2I28_08595 6c2c1194f2c94cb2a6791876d570c84f 169 Pfam PF05991 YacP-like NYN domain 4 166 7.3E-58 T 15-10-2018 IPR010298 Protein of unknown function DUF901 C2I28_14675 f81085d83a14e8e497be3af2f71aea55 78 Gene3D G3DSA:3.30.720.20 1 78 4.0E-30 T 15-10-2018 IPR038073 YkuJ-like superfamily C2I28_14675 f81085d83a14e8e497be3af2f71aea55 78 SUPERFAMILY SSF143567 2 77 1.31E-25 T 15-10-2018 IPR038073 YkuJ-like superfamily C2I28_14675 f81085d83a14e8e497be3af2f71aea55 78 PIRSF PIRSF037356 1 78 9.0E-31 T 15-10-2018 IPR014904 Protein of unknown function DUF1797 C2I28_14675 f81085d83a14e8e497be3af2f71aea55 78 Pfam PF08796 Protein of unknown function (DUF1797) 7 77 4.2E-25 T 15-10-2018 IPR014904 Protein of unknown function DUF1797 C2I28_20640 7422ebeecf2a11678b0ad46be5755c73 325 Pfam PF13536 Putative multidrug resistance efflux transporter 38 304 1.6E-92 T 15-10-2018 IPR032713 Putative multidrug resistance efflux transporter C2I28_02875 ad64542aa890f35685c7be9a035b8c52 95 Gene3D G3DSA:1.20.120.910 10 90 1.0E-7 T 15-10-2018 C2I28_18540 c48c8836737531ffb36c1acb50027ef9 248 Pfam PF03073 TspO/MBR family 17 160 3.3E-10 T 15-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 C2I28_18540 c48c8836737531ffb36c1acb50027ef9 248 Gene3D G3DSA:1.20.1260.100 7 165 5.1E-7 T 15-10-2018 IPR038330 TspO/MBR-related superfamily C2I28_25205 f543c48ae8c299254bed7010c5856a48 257 Pfam PF12679 ABC-2 family transporter protein 51 215 3.8E-7 T 15-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I28_23220 0581d3b7a2eb86164d1e89ffc0721807 419 Gene3D G3DSA:3.30.1490.330 274 370 8.7E-11 T 15-10-2018 C2I28_23220 0581d3b7a2eb86164d1e89ffc0721807 419 SUPERFAMILY SSF56059 9 416 8.59E-41 T 15-10-2018 C2I28_23220 0581d3b7a2eb86164d1e89ffc0721807 419 SUPERFAMILY SSF52440 165 289 5.18E-7 T 15-10-2018 IPR016185 Pre-ATP-grasp domain superfamily C2I28_23220 0581d3b7a2eb86164d1e89ffc0721807 419 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 17 416 7.3E-80 T 15-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain C2I28_22065 6232c99ce5384e2a4c2bbac7354f9b49 115 Pfam PF05656 Protein of unknown function (DUF805) 11 110 6.4E-31 T 15-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 C2I28_07735 1d2798e989f14d304f62878c64f56c6d 151 Pfam PF12821 Threonine/Serine exporter, ThrE 6 134 2.8E-39 T 15-10-2018 IPR024528 Threonine/Serine exporter, ThrE C2I28_13460 70d07a5f35c4ed31a739bc0ee8443106 52 SMART SM00914 12 48 5.3E-4 T 15-10-2018 IPR014957 IDEAL domain C2I28_13460 70d07a5f35c4ed31a739bc0ee8443106 52 Pfam PF08858 IDEAL domain 12 48 6.5E-13 T 15-10-2018 IPR014957 IDEAL domain C2I28_13460 70d07a5f35c4ed31a739bc0ee8443106 52 Gene3D G3DSA:4.10.810.10 2 52 6.4E-14 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_20045 280baa1465621bb9dbf75cd7c1bf81bd 466 PIRSF PIRSF006060 6 465 2.4E-94 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_20045 280baa1465621bb9dbf75cd7c1bf81bd 466 Gene3D G3DSA:1.20.1740.10 22 465 2.3E-128 T 15-10-2018 C2I28_20045 280baa1465621bb9dbf75cd7c1bf81bd 466 Pfam PF13520 Amino acid permease 26 429 2.1E-66 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_14330 841c37479f62d75e8a3a91fce7e38ad1 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 2.5E-46 T 15-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I28_20605 c8397f1cfcad588296aace45861db4d5 405 Gene3D G3DSA:1.20.1250.20 4 390 3.7E-27 T 15-10-2018 C2I28_20605 c8397f1cfcad588296aace45861db4d5 405 Pfam PF07690 Major Facilitator Superfamily 15 338 9.7E-22 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_20605 c8397f1cfcad588296aace45861db4d5 405 SUPERFAMILY SSF103473 8 396 9.16E-38 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_01750 dbafa83a9985658b26c068ee4ea93c66 92 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 4 92 7.0E-43 T 15-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU C2I28_01750 dbafa83a9985658b26c068ee4ea93c66 92 Pfam PF14122 YokU-like protein, putative antitoxin 4 90 3.8E-40 T 15-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU C2I28_01750 dbafa83a9985658b26c068ee4ea93c66 92 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 5 52 1.1E-11 T 15-10-2018 IPR022453 Zinc finger, MqsA-type C2I28_13675 d73e8026ec7b65d2dfe77471b7e5eb5b 456 Pfam PF05159 Capsule polysaccharide biosynthesis protein 124 393 3.5E-35 T 15-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 C2I28_08330 d9b28d86f9b34a38f75e93cb61cacf8a 56 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 54 2.7E-6 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_08330 d9b28d86f9b34a38f75e93cb61cacf8a 56 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 15-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 C2I28_16735 4021dae2cb885d60739694b60549d817 268 Gene3D G3DSA:3.60.110.10 1 265 4.1E-89 T 15-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I28_16735 4021dae2cb885d60739694b60549d817 268 SUPERFAMILY SSF56317 1 256 1.31E-65 T 15-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily C2I28_16735 4021dae2cb885d60739694b60549d817 268 Pfam PF00795 Carbon-nitrogen hydrolase 5 248 6.8E-48 T 15-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 C2I28_01415 2210aee18e7133ce1677882972a20446 52 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 48 1.1E-12 T 15-10-2018 IPR011437 Domain of unknown function DUF1540 C2I28_22855 392f69897a8a288336c6c1617407622b 323 Gene3D G3DSA:3.10.310.30 252 312 2.3E-7 T 15-10-2018 C2I28_22855 392f69897a8a288336c6c1617407622b 323 SUPERFAMILY SSF64182 3 311 1.31E-25 T 15-10-2018 IPR038763 DHH phosphoesterase superfamily C2I28_22855 392f69897a8a288336c6c1617407622b 323 Pfam PF02272 DHHA1 domain 203 310 4.5E-6 T 15-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 C2I28_00610 873ebc3720ffd238970db3f4263de499 280 Pfam PF00583 Acetyltransferase (GNAT) family 173 264 1.3E-5 T 15-10-2018 IPR000182 GNAT domain C2I28_00610 873ebc3720ffd238970db3f4263de499 280 Gene3D G3DSA:3.40.630.30 110 274 2.0E-10 T 15-10-2018 C2I28_00610 873ebc3720ffd238970db3f4263de499 280 SUPERFAMILY SSF55729 142 269 2.36E-12 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_05685 12fbb68b81883997e97b506d99d6598d 201 Pfam PF01588 Putative tRNA binding domain 96 197 1.8E-27 T 15-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 C2I28_05685 12fbb68b81883997e97b506d99d6598d 201 Pfam PF14794 Domain of unknown function (DUF4479) 24 91 1.5E-24 T 15-10-2018 IPR027855 Domain of unknown function DUF4479 C2I28_05685 12fbb68b81883997e97b506d99d6598d 201 SUPERFAMILY SSF50249 92 199 3.43E-33 T 15-10-2018 IPR012340 Nucleic acid-binding, OB-fold C2I28_05685 12fbb68b81883997e97b506d99d6598d 201 Gene3D G3DSA:2.40.50.140 5 199 9.1E-78 T 15-10-2018 C2I28_05685 12fbb68b81883997e97b506d99d6598d 201 Gene3D G3DSA:3.30.1940.10 18 92 9.1E-78 T 15-10-2018 IPR037154 YtpR-like superfamily C2I28_24830 e6732c96c4964b14075c774ff7826a3a 105 SUPERFAMILY SSF46785 7 103 2.34E-28 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_24830 e6732c96c4964b14075c774ff7826a3a 105 Gene3D G3DSA:1.10.10.10 5 105 1.8E-32 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_24830 e6732c96c4964b14075c774ff7826a3a 105 Pfam PF01638 HxlR-like helix-turn-helix 17 104 3.1E-30 T 15-10-2018 IPR002577 Helix-turn-helix, HxlR type C2I28_21525 627434dfd353799ddf4fc6b05686a38c 143 Pfam PF16888 Domain of unknown function (DUF5082) 12 102 3.1E-9 T 15-10-2018 IPR031681 Protein of unknown function DUF5082 C2I28_21525 627434dfd353799ddf4fc6b05686a38c 143 ProDom PD085159 YWQH COILED COIL 1 138 5.0E-23 T 15-10-2018 IPR020326 Uncharacterised protein family YwqH C2I28_13730 10445e3cbb8cda3a80afc40234588c0b 250 Pfam PF13807 G-rich domain on putative tyrosine kinase 142 194 8.1E-8 T 15-10-2018 IPR032807 Tyrosine kinase, G-rich domain C2I28_13730 10445e3cbb8cda3a80afc40234588c0b 250 Pfam PF02706 Chain length determinant protein 3 94 3.5E-23 T 15-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 C2I28_16240 c9b434ae0a62c39e8888ae2fe1dbee89 204 Pfam PF06197 Protein of unknown function (DUF998) 19 199 1.9E-12 T 15-10-2018 IPR009339 Protein of unknown function DUF998 C2I28_04405 1321c3619f1ee7fa6d560fcdb79c167f 111 Pfam PF12438 Protein of unknown function (DUF3679) 7 62 1.2E-20 T 15-10-2018 IPR020534 Uncharacterised protein family YqxA C2I28_04405 1321c3619f1ee7fa6d560fcdb79c167f 111 ProDom PD072942 YQXA ORF79 22 106 9.0E-14 T 15-10-2018 IPR020534 Uncharacterised protein family YqxA C2I28_11915 a426433cef3d5dbe12cf207380272a64 241 Gene3D G3DSA:3.40.50.1820 1 241 5.3E-48 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11915 a426433cef3d5dbe12cf207380272a64 241 SUPERFAMILY SSF53474 7 240 4.14E-36 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_11915 a426433cef3d5dbe12cf207380272a64 241 Pfam PF00756 Putative esterase 15 232 6.6E-48 T 15-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 C2I28_11105 5c25dc8becc1d6d22262a58bd260f94c 631 SUPERFAMILY SSF52266 461 619 4.76E-16 T 15-10-2018 C2I28_11105 5c25dc8becc1d6d22262a58bd260f94c 631 Pfam PF01757 Acyltransferase family 12 329 3.8E-19 T 15-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I28_11105 5c25dc8becc1d6d22262a58bd260f94c 631 Gene3D G3DSA:3.40.50.1110 438 620 1.8E-11 T 15-10-2018 IPR036514 SGNH hydrolase superfamily C2I28_22765 b1c751ef95b68f474b85f011821322a7 50 ProDom PD049467 YFLJ 3 38 5.0E-5 T 15-10-2018 IPR022580 Protein of unknown function DUF2639 C2I28_22765 b1c751ef95b68f474b85f011821322a7 50 Pfam PF11121 Protein of unknown function (DUF2639) 3 39 4.7E-22 T 15-10-2018 IPR022580 Protein of unknown function DUF2639 C2I28_07570 98637a40a8a4e8b7f1ba5f25e361430a 74 Hamap MF_01863 UPF0741 protein . 1 74 31.008 T 15-10-2018 IPR020880 Protein of unknown function UPF0741 C2I28_07570 98637a40a8a4e8b7f1ba5f25e361430a 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 4.8E-10 T 15-10-2018 IPR009910 Protein of unknown function DUF1450 C2I28_07920 5481e3b2fb13269e23ccf6aa220ed200 314 Pfam PF09991 Predicted membrane protein (DUF2232) 15 302 3.9E-72 T 15-10-2018 IPR018710 Protein of unknown function DUF2232 C2I28_21145 0f123e5cd912f1207f40773f573611de 522 SUPERFAMILY SSF46785 431 515 1.01E-5 T 15-10-2018 IPR036390 Winged helix DNA-binding domain superfamily C2I28_21145 0f123e5cd912f1207f40773f573611de 522 Gene3D G3DSA:1.10.10.10 392 521 8.8E-8 T 15-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily C2I28_21145 0f123e5cd912f1207f40773f573611de 522 Pfam PF09382 RQC domain 431 512 8.2E-8 T 15-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 C2I28_13305 1d5169dd5784cc46748b2f7553f02de7 399 Pfam PF01425 Amidase 19 198 3.4E-54 T 15-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_13305 1d5169dd5784cc46748b2f7553f02de7 399 Pfam PF01425 Amidase 268 380 5.5E-9 T 15-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_13305 1d5169dd5784cc46748b2f7553f02de7 399 SUPERFAMILY SSF75304 6 384 9.68E-90 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_13305 1d5169dd5784cc46748b2f7553f02de7 399 ProSitePatterns PS00571 Amidases signature. 106 137 - T 15-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 C2I28_13305 1d5169dd5784cc46748b2f7553f02de7 399 Gene3D G3DSA:3.90.1300.10 11 387 1.0E-89 T 15-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 C2I28_10055 aa06459ed58569b9f0e0d6fb8c34d17f 300 Pfam PF08338 Domain of unknown function (DUF1731) 253 299 4.1E-17 T 15-10-2018 IPR013549 Domain of unknown function DUF1731 C2I28_10055 aa06459ed58569b9f0e0d6fb8c34d17f 300 SUPERFAMILY SSF51735 1 299 7.19E-41 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10055 aa06459ed58569b9f0e0d6fb8c34d17f 300 Gene3D G3DSA:3.40.50.720 1 290 2.5E-74 T 15-10-2018 C2I28_10055 aa06459ed58569b9f0e0d6fb8c34d17f 300 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 296 4.7E-109 T 15-10-2018 IPR010099 Epimerase family protein SDR39U1 C2I28_10055 aa06459ed58569b9f0e0d6fb8c34d17f 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 217 3.9E-14 T 15-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 C2I28_04740 cf3bf263d6b02066bc3664b93a8618e1 127 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 9 121 1.1E-26 T 15-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane C2I28_04740 cf3bf263d6b02066bc3664b93a8618e1 127 Pfam PF12670 Protein of unknown function (DUF3792) 8 118 1.3E-20 T 15-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane C2I28_02460 0b988af1436e3862012d09e8654540c8 213 Pfam PF04347 Flagellar biosynthesis protein, FliO 87 190 1.7E-12 T 15-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 C2I28_12665 e5daf4cb022682a479a34ed1a3bb5529 76 SUPERFAMILY SSF50037 4 74 6.1E-15 T 15-10-2018 IPR008988 Transcriptional repressor, C-terminal C2I28_12665 e5daf4cb022682a479a34ed1a3bb5529 76 Gene3D G3DSA:2.30.30.90 2 76 2.8E-17 T 15-10-2018 IPR038157 Ferrous iron transporter, core domain C2I28_12665 e5daf4cb022682a479a34ed1a3bb5529 76 Pfam PF04023 FeoA domain 2 74 1.7E-13 T 15-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I28_12665 e5daf4cb022682a479a34ed1a3bb5529 76 SMART SM00899 2 75 1.7E-14 T 15-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 C2I28_15245 291acf1f66d7a6485272cf180810fc08 415 Pfam PF01547 Bacterial extracellular solute-binding protein 46 332 2.8E-33 T 15-10-2018 IPR006059 Bacterial extracellular solute-binding protein C2I28_15245 291acf1f66d7a6485272cf180810fc08 415 Gene3D G3DSA:3.40.190.10 51 355 1.8E-73 T 15-10-2018 C2I28_15245 291acf1f66d7a6485272cf180810fc08 415 Gene3D G3DSA:3.40.190.10 144 402 1.8E-73 T 15-10-2018 C2I28_15245 291acf1f66d7a6485272cf180810fc08 415 SUPERFAMILY SSF53850 16 413 2.76E-73 T 15-10-2018 C2I28_01605 666f37fa3c8533133c8aab91fefaa7fb 269 Pfam PF14344 Domain of unknown function (DUF4397) 130 224 5.2E-18 T 15-10-2018 IPR025510 Domain of unknown function DUF4397 C2I28_01605 666f37fa3c8533133c8aab91fefaa7fb 269 Pfam PF14344 Domain of unknown function (DUF4397) 31 146 1.1E-34 T 15-10-2018 IPR025510 Domain of unknown function DUF4397 C2I28_04335 07c6ec9abfc6dde628bb337378e20657 153 PIRSF PIRSF021361 8 153 6.2E-55 T 15-10-2018 IPR016788 Uncharacterised conserved protein UCP021361 C2I28_21420 4fd9f5d01eaa597299d6a1518b1ca4c1 528 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 189 333 8.4E-8 T 15-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like C2I28_08070 f4af7801695e35e71831fad90d6ed410 321 Pfam PF14175 YaaC-like Protein 11 312 3.9E-95 T 15-10-2018 IPR026988 YaaC-like protein C2I28_24705 7d825258fb19bd7a212948866d219993 87 Pfam PF05901 Excalibur calcium-binding domain 32 86 5.9E-14 T 15-10-2018 IPR008613 Excalibur calcium-binding domain C2I28_24705 7d825258fb19bd7a212948866d219993 87 SMART SM00894 31 86 9.5E-7 T 15-10-2018 IPR008613 Excalibur calcium-binding domain C2I28_16525 bd6b798428b0fa51012ce0a15f15ec6b 170 Gene3D G3DSA:1.20.1260.50 2 163 2.4E-10 T 15-10-2018 C2I28_27405 ef1e94576d42ad6cbbc71f80b5009e1e 142 Pfam PF07552 Spore Coat Protein X and V domain 85 141 2.1E-19 T 15-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I28_27405 ef1e94576d42ad6cbbc71f80b5009e1e 142 Pfam PF07552 Spore Coat Protein X and V domain 21 77 1.1E-19 T 15-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 C2I28_24080 df92760469f6ebde5ced996892146a84 137 Pfam PF07485 Domain of Unknown Function (DUF1259) 10 122 1.6E-24 T 15-10-2018 IPR011094 Uncharacterised protein family, LppY/LpqO C2I28_21055 901fdaa87a4d9ef08db1231e836e4b0e 146 Pfam PF03780 Asp23 family, cell envelope-related function 18 124 5.4E-36 T 15-10-2018 IPR005531 Alkaline shock protein Asp23 C2I28_11960 ee2e990e9ab8b12af1f6cb16d3e547a0 442 Pfam PF02447 GntP family permease 5 440 2.2E-145 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_11960 ee2e990e9ab8b12af1f6cb16d3e547a0 442 PIRSF PIRSF002746 1 442 1.2E-144 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_11960 ee2e990e9ab8b12af1f6cb16d3e547a0 442 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 6 442 2.4E-139 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_23565 1aaa4015426e201ee26501a456aeb5f2 264 SUPERFAMILY SSF110710 1 262 4.18E-95 T 15-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like C2I28_23565 1aaa4015426e201ee26501a456aeb5f2 264 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 33 261 6.7E-81 T 15-10-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 C2I28_09570 200e9cbe8a9be8fb06d83b752d0e4bc8 912 Gene3D G3DSA:1.25.40.10 9 188 6.8E-6 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_09570 200e9cbe8a9be8fb06d83b752d0e4bc8 912 SUPERFAMILY SSF52540 467 544 2.83E-8 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_09570 200e9cbe8a9be8fb06d83b752d0e4bc8 912 Gene3D G3DSA:3.40.50.300 381 589 2.5E-11 T 15-10-2018 C2I28_22555 4887fac17365a4ac5885a275fc99b8bb 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.4E-23 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_13855 990a82afaafab110ee8101ba78b26a2c 108 SUPERFAMILY SSF50022 7 107 1.57E-30 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_13855 990a82afaafab110ee8101ba78b26a2c 108 Pfam PF00355 Rieske [2Fe-2S] domain 9 87 7.9E-14 T 15-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 C2I28_13855 990a82afaafab110ee8101ba78b26a2c 108 Gene3D G3DSA:2.102.10.10 4 108 2.6E-26 T 15-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 C2I28_13855 990a82afaafab110ee8101ba78b26a2c 108 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 7 104 2.3E-29 T 15-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 C2I28_18915 5a7a3da058dc51b6bb94148cba668442 386 Pfam PF04230 Polysaccharide pyruvyl transferase 13 316 9.1E-31 T 15-10-2018 IPR007345 Polysaccharide pyruvyl transferase C2I28_01280 2790b99443d19498fa4fd186ca535d4f 237 Pfam PF06912 Protein of unknown function (DUF1275) 27 227 1.7E-44 T 15-10-2018 IPR010699 Protein of unknown function DUF1275 C2I28_17890 71d0928a2c0ee3d06f25163fc15da4aa 253 Gene3D G3DSA:1.10.10.1320 3 99 2.4E-10 T 15-10-2018 C2I28_17890 71d0928a2c0ee3d06f25163fc15da4aa 253 Pfam PF10099 Anti-sigma-K factor rskA 56 250 1.7E-24 T 15-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 C2I28_02945 a78fe665d69eb4776861fdc7a7e497df 252 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 252 29.327 T 15-10-2018 IPR026580 Cell division protein DivIB C2I28_02945 a78fe665d69eb4776861fdc7a7e497df 252 Pfam PF03799 Cell division protein FtsQ 122 238 2.6E-7 T 15-10-2018 IPR005548 Cell division protein FtsQ/DivIB C2I28_02945 a78fe665d69eb4776861fdc7a7e497df 252 Gene3D G3DSA:3.40.50.10960 117 233 1.7E-38 T 15-10-2018 C2I28_02945 a78fe665d69eb4776861fdc7a7e497df 252 Pfam PF08478 POTRA domain, FtsQ-type 50 118 8.8E-23 T 15-10-2018 IPR013685 POTRA domain, FtsQ-type C2I28_02945 a78fe665d69eb4776861fdc7a7e497df 252 Gene3D G3DSA:3.10.20.310 50 116 1.0E-9 T 15-10-2018 C2I28_25230 986bbc88a755625c09f1c12f0da27145 488 Pfam PF00916 Sulfate permease family 14 354 1.5E-57 T 15-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 C2I28_25230 986bbc88a755625c09f1c12f0da27145 488 SUPERFAMILY SSF52091 386 480 1.65E-10 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_25230 986bbc88a755625c09f1c12f0da27145 488 Gene3D G3DSA:3.30.750.24 381 479 3.9E-24 T 15-10-2018 IPR036513 STAS domain superfamily C2I28_25230 986bbc88a755625c09f1c12f0da27145 488 Pfam PF01740 STAS domain 390 480 3.5E-7 T 15-10-2018 IPR002645 STAS domain C2I28_01325 c8b5cf6ddddf0b902ad368e7f98bbdf8 294 Pfam PF14358 Domain of unknown function (DUF4405) 77 135 4.4E-11 T 15-10-2018 IPR025517 Domain of unknown function DUF4405 C2I28_01325 c8b5cf6ddddf0b902ad368e7f98bbdf8 294 SUPERFAMILY SSF81342 25 135 1.7E-6 T 15-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 C2I28_10935 de9925adfa886b076a58711df7d1cf8d 206 Pfam PF13460 NAD(P)H-binding 7 189 1.1E-33 T 15-10-2018 IPR016040 NAD(P)-binding domain C2I28_10935 de9925adfa886b076a58711df7d1cf8d 206 SUPERFAMILY SSF51735 1 194 6.14E-27 T 15-10-2018 IPR036291 NAD(P)-binding domain superfamily C2I28_10935 de9925adfa886b076a58711df7d1cf8d 206 Gene3D G3DSA:3.40.50.720 1 205 4.1E-37 T 15-10-2018 C2I28_03790 c906546124e2d1521458816ba3440e2d 83 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 20 77 1.0E-9 T 15-10-2018 IPR020138 Uncharacterised protein family YqzF C2I28_03790 c906546124e2d1521458816ba3440e2d 83 Pfam PF11118 Protein of unknown function (DUF2627) 3 77 1.6E-37 T 15-10-2018 IPR020138 Uncharacterised protein family YqzF C2I28_18955 9684b8d44d9c73ad0d65239f140f272c 310 Gene3D G3DSA:3.40.50.300 115 191 1.1E-10 T 15-10-2018 C2I28_18955 9684b8d44d9c73ad0d65239f140f272c 310 SUPERFAMILY SSF53795 116 177 7.32E-15 T 15-10-2018 C2I28_21510 d072f73cda66afb77c4b727e8ca518c0 171 Pfam PF14434 Immunity protein Imm6 12 128 2.2E-33 T 15-10-2018 IPR025674 Immunity protein Imm6 C2I28_22640 4b4ab1e0f5699f93f9a249ab4077ca25 391 Pfam PF12051 Protein of unknown function (DUF3533) 15 348 3.1E-24 T 15-10-2018 IPR022703 Domain of unknown function DUF3533 C2I28_02180 e1911ef639ab273685098d1f956f7cd5 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 261 2.1E-107 T 15-10-2018 IPR024514 Domain of unknown function DUF3388 C2I28_02180 e1911ef639ab273685098d1f956f7cd5 263 SUPERFAMILY SSF55021 5 75 2.54E-7 T 15-10-2018 C2I28_02180 e1911ef639ab273685098d1f956f7cd5 263 PIRSF PIRSF021288 1 262 1.9E-144 T 15-10-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain C2I28_25890 51bb2b7589a951a8004027cd95713840 893 Gene3D G3DSA:1.25.40.10 203 369 1.7E-7 T 15-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 C2I28_24900 3e3612187fd73003513be4b5157150a1 176 Pfam PF07155 ECF-type riboflavin transporter, S component 12 170 6.4E-42 T 15-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 C2I28_24900 3e3612187fd73003513be4b5157150a1 176 Gene3D G3DSA:1.10.1760.20 9 173 3.8E-46 T 15-10-2018 C2I28_06365 461c0c70dd50820011fb6772e7a0e7ab 158 Pfam PF02681 Divergent PAP2 family 5 149 1.0E-50 T 15-10-2018 IPR003832 Protein of unknown function DUF212 C2I28_10485 43ef8c24c5bc43e9842ba2bd3eae859e 388 Pfam PF05684 Protein of unknown function (DUF819) 11 386 1.6E-120 T 15-10-2018 IPR008537 Protein of unknown function DUF819 C2I28_03045 35dbd309889d118b54e1febbc2cd8bd6 172 Pfam PF02620 Uncharacterized ACR, COG1399 56 166 2.2E-22 T 15-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD C2I28_19555 d2b66dee16c98282b41993217ed7ae80 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 2.8E-17 T 15-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 C2I28_19555 d2b66dee16c98282b41993217ed7ae80 67 Gene3D G3DSA:1.10.8.910 6 65 3.2E-23 T 15-10-2018 IPR038300 SASP, alpha/beta-type superfamily C2I28_23150 3e5cbe280e6322279d34cd5d83059891 176 Pfam PF02417 Chromate transporter 5 171 5.1E-39 T 15-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 C2I28_24810 bee1322c3eb7658bfdda8c659c8792b2 189 SUPERFAMILY SSF140478 27 174 4.05E-56 T 15-10-2018 IPR023353 LemA-like domain superfamily C2I28_24810 bee1322c3eb7658bfdda8c659c8792b2 189 Pfam PF04011 LemA family 9 185 6.6E-75 T 15-10-2018 IPR007156 LemA C2I28_24810 bee1322c3eb7658bfdda8c659c8792b2 189 Gene3D G3DSA:1.20.1440.20 17 185 1.9E-73 T 15-10-2018 IPR023353 LemA-like domain superfamily C2I28_15350 ebb8a7b380a709917a015641c0aac9b3 60 Pfam PF10782 Zinc-finger 2 58 1.6E-28 T 15-10-2018 IPR019718 Protein of unknown function DUF2602 C2I28_20835 1b985cfcefcdc24a99558c7cfe788a22 273 Gene3D G3DSA:3.40.50.1820 2 270 1.4E-71 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_20835 1b985cfcefcdc24a99558c7cfe788a22 273 Pfam PF00561 alpha/beta hydrolase fold 23 254 1.3E-25 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20835 1b985cfcefcdc24a99558c7cfe788a22 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 2.1E-14 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20835 1b985cfcefcdc24a99558c7cfe788a22 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 2.1E-14 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20835 1b985cfcefcdc24a99558c7cfe788a22 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 2.1E-14 T 15-10-2018 IPR000073 Alpha/beta hydrolase fold-1 C2I28_20835 1b985cfcefcdc24a99558c7cfe788a22 273 SUPERFAMILY SSF53474 4 267 1.76E-57 T 15-10-2018 IPR029058 Alpha/Beta hydrolase fold C2I28_12680 ea41ba6d69909c43467d190aa3ca2997 283 Pfam PF00398 Ribosomal RNA adenine dimethylase 67 124 1.8E-5 T 15-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm C2I28_12680 ea41ba6d69909c43467d190aa3ca2997 283 Gene3D G3DSA:3.40.50.150 35 282 3.1E-13 T 15-10-2018 C2I28_12680 ea41ba6d69909c43467d190aa3ca2997 283 SUPERFAMILY SSF53335 70 170 2.81E-17 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_24805 4059cc82f7ea748286724ba5fd9ec8f0 257 Gene3D G3DSA:3.10.310.50 21 168 9.3E-49 T 15-10-2018 C2I28_24805 4059cc82f7ea748286724ba5fd9ec8f0 257 Pfam PF04536 TPM domain 36 159 5.4E-37 T 15-10-2018 IPR007621 TPM domain C2I28_19955 03eb5cca365c188fff65112fca7a4f6f 493 Pfam PF00324 Amino acid permease 28 482 1.9E-135 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_19955 03eb5cca365c188fff65112fca7a4f6f 493 Gene3D G3DSA:1.20.1740.10 18 488 3.8E-60 T 15-10-2018 C2I28_19955 03eb5cca365c188fff65112fca7a4f6f 493 PIRSF PIRSF006060 1 493 8.6E-87 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_19955 03eb5cca365c188fff65112fca7a4f6f 493 ProSitePatterns PS00218 Amino acid permeases signature. 53 84 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_06250 15add8fbdb8ea936ec31af482d57bf39 140 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 7 131 1.5E-33 T 15-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein C2I28_22075 0e8fb7420c37bf176efbf205fdcd3811 409 Gene3D G3DSA:1.20.1250.20 10 393 4.7E-35 T 15-10-2018 C2I28_22075 0e8fb7420c37bf176efbf205fdcd3811 409 Pfam PF07690 Major Facilitator Superfamily 15 356 1.8E-26 T 15-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 C2I28_22075 0e8fb7420c37bf176efbf205fdcd3811 409 SUPERFAMILY SSF103473 7 393 1.31E-43 T 15-10-2018 IPR036259 MFS transporter superfamily C2I28_21010 8cc6e253b6e0b08b33663750cecd21a0 231 SUPERFAMILY SSF53335 13 178 4.8E-9 T 15-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase C2I28_27735 b1b0a1153f7bf58d51caf1a0f9a1f3dc 110 Gene3D G3DSA:2.60.40.10 3 90 2.4E-8 T 15-10-2018 IPR013783 Immunoglobulin-like fold C2I28_27735 b1b0a1153f7bf58d51caf1a0f9a1f3dc 110 SUPERFAMILY SSF49313 8 90 3.14E-5 T 15-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 C2I28_14565 a278f3bdb07f0b5583c7dda1d7b955b1 228 Pfam PF04172 LrgB-like family 12 223 6.1E-71 T 15-10-2018 IPR007300 CidB/LrgB family C2I28_23660 9da0f578fc3caaf74bfb9c4effd64328 92 Gene3D G3DSA:1.10.1740.10 5 71 7.9E-10 T 15-10-2018 C2I28_23660 9da0f578fc3caaf74bfb9c4effd64328 92 SUPERFAMILY SSF88946 3 60 1.96E-7 T 15-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 C2I28_23060 2194a3a84ed75c941165d5871ad6977e 89 Pfam PF14206 Cysteine-rich CPCC 4 75 5.7E-30 T 15-10-2018 IPR025983 Cysteine-rich CPCC domain C2I28_00955 ba0d645faa2a4d0c7967c4340f31085a 135 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 10 116 2.0E-26 T 15-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ C2I28_00955 ba0d645faa2a4d0c7967c4340f31085a 135 Pfam PF11033 Competence protein J (ComJ) 9 133 9.2E-42 T 15-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ C2I28_00955 ba0d645faa2a4d0c7967c4340f31085a 135 Gene3D G3DSA:2.60.34.30 1 132 5.1E-47 T 15-10-2018 IPR038691 DNA-entry nuclease inhibitor, ComJ superfamily C2I28_03270 918d1dfddeec6d0cab997fe3ce596abc 201 PIRSF PIRSF036710 1 201 1.7E-49 T 15-10-2018 IPR014617 Predicted membrane protein, Bacillus YphA type C2I28_04540 fe4b0adbf66d2007804f052df9b75e59 71 Pfam PF10750 Protein of unknown function (DUF2536) 1 68 5.3E-34 T 15-10-2018 IPR019686 Protein of unknown function DUF2536 C2I28_11085 c7e92e251d0da7746bb841e159360c4b 176 Pfam PF17099 Tryptophan transporter TrpP 2 166 1.3E-51 T 15-10-2018 IPR031360 Tryptophan transporter TrpP C2I28_11085 c7e92e251d0da7746bb841e159360c4b 176 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 174 3.0E-48 T 15-10-2018 C2I28_22720 bbd1ce9499317f662c1ea18e53af1798 365 Pfam PF01757 Acyltransferase family 5 341 2.3E-26 T 15-10-2018 IPR002656 Acyltransferase 3 GO:0016747 C2I28_15460 763fa3c3b495a4f1ab7d5b257c7810f1 335 Gene3D G3DSA:1.10.3470.10 8 334 4.1E-99 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_15460 763fa3c3b495a4f1ab7d5b257c7810f1 335 Pfam PF01032 FecCD transport family 22 329 1.0E-98 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_15460 763fa3c3b495a4f1ab7d5b257c7810f1 335 SUPERFAMILY SSF81345 5 329 1.7E-85 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_02205 0bcda60bfd25395cac4f16e24974f819 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 287 2.7E-42 T 15-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 C2I28_03435 46a5c93a7a806dd4d436ccadd26a9b8e 199 Pfam PF07670 Nucleoside recognition 43 149 9.6E-12 T 15-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 C2I28_03115 7640466a078321fac009b2b1db8d5b44 195 Pfam PF07187 Protein of unknown function (DUF1405) 24 181 4.9E-57 T 15-10-2018 IPR009845 Protein of unknown function DUF1405 C2I28_21390 a897b786a0b85038e114e36ce7ded98d 368 Pfam PF12698 ABC-2 family transporter protein 20 358 2.9E-27 T 15-10-2018 C2I28_25450 29584de753844a9c6e0da3b5607144d3 209 Pfam PF02517 CAAX protease self-immunity 103 198 8.4E-14 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_04305 bfded429dbe671a33fde41834eb6461a 123 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 71 82 - T 15-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 C2I28_04305 bfded429dbe671a33fde41834eb6461a 123 Pfam PF01219 Prokaryotic diacylglycerol kinase 17 118 3.3E-34 T 15-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 C2I28_04305 bfded429dbe671a33fde41834eb6461a 123 Gene3D G3DSA:1.10.3830.10 3 122 9.2E-40 T 15-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 C2I28_26620 672eba65f6dc2cb44f3b2b06a7c97568 150 Pfam PF14119 Domain of unknown function (DUF4288) 13 108 4.6E-22 T 15-10-2018 IPR025630 Protein of unknown function DUF4288 C2I28_25540 31bff212710252315246126d1640578d 205 Pfam PF01184 GPR1/FUN34/yaaH family 9 196 2.0E-24 T 15-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 C2I28_11850 be34d8989919f7a41e19166ac6b47fe7 111 Pfam PF07098 Protein of unknown function (DUF1360) 8 109 1.4E-39 T 15-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 C2I28_21945 82e1e3f88d198cd6c8af3860dede4263 310 Gene3D G3DSA:1.10.3720.10 67 309 1.1E-70 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_21945 82e1e3f88d198cd6c8af3860dede4263 310 SUPERFAMILY SSF160964 30 74 2.09E-6 T 15-10-2018 C2I28_21945 82e1e3f88d198cd6c8af3860dede4263 310 SUPERFAMILY SSF161098 71 296 4.58E-62 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_21945 82e1e3f88d198cd6c8af3860dede4263 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 299 3.4E-20 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_10105 c22fac68efe432c7093c1b7f32fef324 97 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 10 91 1.1E-31 T 15-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 C2I28_10105 c22fac68efe432c7093c1b7f32fef324 97 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 11 91 1.6E-25 T 15-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 C2I28_11405 ae49559bd59e10cc35fac567b6655366 93 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 3 52 2.0E-10 T 15-10-2018 IPR024255 Spore germination GerPB C2I28_11405 ae49559bd59e10cc35fac567b6655366 93 Pfam PF10803 Spore germination GerPB 3 53 2.8E-26 T 15-10-2018 IPR024255 Spore germination GerPB C2I28_13930 af1f95e9eb2c68bb44df1a66a974d9d9 172 Pfam PF14435 SUKH-4 immunity protein 12 166 1.2E-19 T 15-10-2018 IPR025851 SUKH-4 immunity protein C2I28_15635 7fc7ca36891f75cbcfc33ca31c3983a0 336 Gene3D G3DSA:1.10.3470.10 7 334 4.7E-88 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_15635 7fc7ca36891f75cbcfc33ca31c3983a0 336 SUPERFAMILY SSF81345 7 330 2.35E-79 T 15-10-2018 IPR037294 ABC transporter, BtuC-like C2I28_15635 7fc7ca36891f75cbcfc33ca31c3983a0 336 Pfam PF01032 FecCD transport family 22 330 9.3E-87 T 15-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 C2I28_21910 e41467e1aa4ee662278fb57df3e755cc 825 Pfam PF14436 Bacterial EndoU nuclease 676 819 6.4E-11 T 15-10-2018 IPR029501 Bacterial EndoU nuclease C2I28_21910 e41467e1aa4ee662278fb57df3e755cc 825 Pfam PF04740 LXG domain of WXG superfamily 25 223 7.2E-51 T 15-10-2018 IPR006829 LXG domain C2I28_20355 7ccf5a904b4230474c09e8caf341edbb 114 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 110 2.5E-33 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_16480 e2c09f1cd5f4a1af297a978957a87087 442 PIRSF PIRSF006351 1 439 2.4E-127 T 15-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 C2I28_16480 e2c09f1cd5f4a1af297a978957a87087 442 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 430 2.0E-119 T 15-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 C2I28_16480 e2c09f1cd5f4a1af297a978957a87087 442 Pfam PF02378 Phosphotransferase system, EIIC 28 358 6.5E-63 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_16215 416debb622a7c7a38d92dcc54a09676e 127 Pfam PF06803 Protein of unknown function (DUF1232) 32 68 1.3E-13 T 15-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 C2I28_04010 0cfbe887200718374173114fdf7ba396 145 Pfam PF15980 Putative Competence protein ComGF 43 124 1.3E-18 T 15-10-2018 IPR016977 Competence operon G, ComGF C2I28_04010 0cfbe887200718374173114fdf7ba396 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 3.2E-6 T 15-10-2018 IPR012902 Prokaryotic N-terminal methylation site C2I28_10310 ac3c1b35f8bab4d901f4c9e8ff8f207e 1410 Gene3D G3DSA:3.40.50.300 188 378 4.4E-5 T 15-10-2018 C2I28_10310 ac3c1b35f8bab4d901f4c9e8ff8f207e 1410 SUPERFAMILY SSF52540 186 349 5.88E-6 T 15-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase C2I28_21445 d908faa4cb5371aa6279534372d7af02 94 SUPERFAMILY SSF159173 3 93 4.32E-35 T 15-10-2018 IPR023105 YkvR-like superfamily C2I28_21445 d908faa4cb5371aa6279534372d7af02 94 Pfam PF11514 Protein of unknown function (DUF3219) 5 93 1.2E-37 T 15-10-2018 IPR021596 Protein of unknown function DUF3219 C2I28_21445 d908faa4cb5371aa6279534372d7af02 94 Gene3D G3DSA:2.40.30.80 1 92 1.5E-37 T 15-10-2018 IPR023105 YkvR-like superfamily C2I28_07000 e28eb41997272e57a8ec337904ab7c82 74 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 4 71 1.2E-22 T 15-10-2018 IPR019242 Protein of unknown function DUF2198 C2I28_16595 734ca13a0942c3491dc2a74431fc872d 231 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 128 228 1.3E-7 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_16595 734ca13a0942c3491dc2a74431fc872d 231 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 7 107 2.2E-19 T 15-10-2018 IPR018745 Domain of unknown function DUF2294 C2I28_05540 0034f9c37d1c7a315722e018c96b7174 167 Pfam PF06271 RDD family 30 155 5.2E-23 T 15-10-2018 IPR010432 RDD C2I28_13605 07179b2764420a09ea6656afc259cce9 485 PIRSF PIRSF032522 1 484 1.3E-41 T 15-10-2018 IPR023599 Membrane-associated protein TcaA GO:0016021|GO:0046677 C2I28_00525 d7b72798b406e73416bb7bb4568c3c68 189 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 16 169 3.5E-18 T 15-10-2018 IPR025847 MEDS domain C2I28_01305 7c5b65347c6e0ed65e2b9ef60a8d0abf 117 SUPERFAMILY SSF51182 7 103 2.07E-17 T 15-10-2018 IPR011051 RmlC-like cupin domain superfamily C2I28_01305 7c5b65347c6e0ed65e2b9ef60a8d0abf 117 Gene3D G3DSA:2.60.120.10 20 111 4.3E-16 T 15-10-2018 IPR014710 RmlC-like jelly roll fold C2I28_01305 7c5b65347c6e0ed65e2b9ef60a8d0abf 117 Pfam PF07883 Cupin domain 33 100 4.8E-11 T 15-10-2018 IPR013096 Cupin 2, conserved barrel C2I28_21240 1873af38144665a6c99dc3df4ea121f3 125 PIRSF PIRSF033725 2 125 2.5E-24 T 15-10-2018 IPR017020 Uncharacterised conserved protein UCP033725 C2I28_22835 a3f49f83240ee470b0bc8f097e9a6f74 187 Pfam PF02698 DUF218 domain 37 177 4.5E-30 T 15-10-2018 IPR003848 Domain of unknown function DUF218 C2I28_19720 3688e6f5ab8b583a41a0ce44b04c6672 46 TIGRFAM TIGR03093 SASP_sspL: small, acid-soluble spore protein L 9 45 2.7E-19 T 15-10-2018 IPR017526 Small acid-soluble spore protein, SspL C2I28_12480 335d303f342ea4693be30366b3df1c5e 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 276 1.1E-24 T 15-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 C2I28_12480 335d303f342ea4693be30366b3df1c5e 281 Gene3D G3DSA:1.10.3720.10 86 280 1.1E-35 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_12480 335d303f342ea4693be30366b3df1c5e 281 SUPERFAMILY SSF161098 86 270 5.1E-39 T 15-10-2018 IPR035906 MetI-like superfamily C2I28_03485 bdbfb06e0d87c599b34f3394936bb7e9 493 PIRSF PIRSF005690 6 492 1.4E-131 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_03485 bdbfb06e0d87c599b34f3394936bb7e9 493 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 27 479 2.8E-148 T 15-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 C2I28_15950 5ea5fb5a34076b7864676aae7fec1cca 275 Gene3D G3DSA:3.40.190.10 39 272 2.4E-93 T 15-10-2018 C2I28_15950 5ea5fb5a34076b7864676aae7fec1cca 275 PIRSF PIRSF002854 1 275 4.2E-98 T 15-10-2018 IPR004872 Lipoprotein NlpA family C2I28_15950 5ea5fb5a34076b7864676aae7fec1cca 275 SUPERFAMILY SSF53850 39 275 1.24E-76 T 15-10-2018 C2I28_15950 5ea5fb5a34076b7864676aae7fec1cca 275 Pfam PF03180 NLPA lipoprotein 39 275 1.6E-86 T 15-10-2018 IPR004872 Lipoprotein NlpA family C2I28_15950 5ea5fb5a34076b7864676aae7fec1cca 275 Gene3D G3DSA:3.40.190.10 120 225 2.4E-93 T 15-10-2018 C2I28_18465 cdbfec85d39714ccf4afa502f7c1ff8a 244 Pfam PF12730 ABC-2 family transporter protein 7 179 2.9E-19 T 15-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I28_20830 ad7f8d1edc932024f43587f79f65a461 213 Pfam PF01810 LysE type translocator 15 204 4.6E-30 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_15480 e84b3918845fa9b15a39d88bd2c8015a 183 Pfam PF09335 SNARE associated Golgi protein 33 150 3.2E-18 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_00095 2762f720c8566ebd7b21162000e698ff 389 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 31 381 2.2E-77 T 15-10-2018 IPR010640 Low temperature requirement A C2I28_11730 780c9f36ec9e2dc124b86e8ae4c6be1a 454 Gene3D G3DSA:1.20.1740.10 11 454 3.6E-63 T 15-10-2018 C2I28_11730 780c9f36ec9e2dc124b86e8ae4c6be1a 454 Pfam PF00324 Amino acid permease 18 447 2.9E-118 T 15-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 C2I28_11730 780c9f36ec9e2dc124b86e8ae4c6be1a 454 PIRSF PIRSF006060 1 454 2.8E-71 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_11730 780c9f36ec9e2dc124b86e8ae4c6be1a 454 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 15-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 C2I28_00940 c2992ae644d4d6250a7488b3e5616d45 649 Pfam PF13515 Fusaric acid resistance protein-like 371 496 1.2E-23 T 15-10-2018 C2I28_00940 c2992ae644d4d6250a7488b3e5616d45 649 Pfam PF12805 FUSC-like inner membrane protein yccS 96 249 4.3E-7 T 15-10-2018 IPR032692 Integral membrane protein YccS, N-terminal C2I28_17155 3a13b87ba488fdb5f77a4bd83873717b 474 Gene3D G3DSA:1.20.1730.10 27 473 5.5E-57 T 15-10-2018 IPR038377 Sodium/glucose symporter superfamily C2I28_17155 3a13b87ba488fdb5f77a4bd83873717b 474 Pfam PF00474 Sodium:solute symporter family 41 402 3.3E-20 T 15-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 C2I28_02050 a4f1ffe869585d737db32e521a00ad07 608 Gene3D G3DSA:1.20.1740.10 24 470 1.4E-25 T 15-10-2018 C2I28_02050 a4f1ffe869585d737db32e521a00ad07 608 Pfam PF13520 Amino acid permease 26 446 1.5E-32 T 15-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 C2I28_12305 7dda0842fcb58e146f6e18f02b9d6777 289 Pfam PF13349 Putative adhesin 45 287 1.5E-39 T 15-10-2018 IPR025164 Putative adhesin C2I28_20885 33582c05dd2f77241c4779de544e4476 47 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 47 19.004 T 15-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 C2I28_20885 33582c05dd2f77241c4779de544e4476 47 Pfam PF08177 Small acid-soluble spore protein N family 1 46 2.5E-26 T 15-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 C2I28_17040 a559e79ba176e8bb0ea52c8780d5f76e 475 Pfam PF03606 C4-dicarboxylate anaerobic carrier 20 468 3.1E-79 T 15-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 C2I28_11420 78aaafe357f55ce4c8d9c2337a74e3c2 115 Pfam PF07457 Protein of unknown function (DUF1516) 4 110 7.0E-28 T 15-10-2018 IPR010899 Protein of unknown function UPF0344 C2I28_07545 08516262539f325c5c4293b3fec6bf85 170 Pfam PF08741 YwhD family 6 167 8.5E-83 T 15-10-2018 IPR014852 Uncharacterised protein YwhD C2I28_18235 6b30d8495976dd050f01dc46ece576fb 69 Pfam PF14375 Cysteine-rich CWC 10 60 1.8E-13 T 15-10-2018 IPR032720 Cysteine-rich CWC C2I28_09145 7401c30e4ee90575a67896d96fa2f885 93 Gene3D G3DSA:1.10.1220.10 1 93 1.1E-41 T 15-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 C2I28_14015 bdfe41bc5ff25ee43d89cbfd8f9f259e 121 Pfam PF13411 MerR HTH family regulatory protein 2 59 2.5E-13 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_14015 bdfe41bc5ff25ee43d89cbfd8f9f259e 121 Gene3D G3DSA:1.10.1660.10 1 111 9.3E-19 T 15-10-2018 C2I28_14015 bdfe41bc5ff25ee43d89cbfd8f9f259e 121 SUPERFAMILY SSF46955 2 86 5.49E-16 T 15-10-2018 IPR009061 Putative DNA-binding domain superfamily C2I28_14015 bdfe41bc5ff25ee43d89cbfd8f9f259e 121 SMART SM00422 1 61 4.0E-10 T 15-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 C2I28_02010 3f5c9dd8e044c1784ee194cb67a53d33 109 Pfam PF01476 LysM domain 43 95 2.4E-8 T 15-10-2018 IPR018392 LysM domain C2I28_02010 3f5c9dd8e044c1784ee194cb67a53d33 109 Gene3D G3DSA:3.10.350.10 33 105 7.8E-9 T 15-10-2018 IPR036779 LysM domain superfamily C2I28_02010 3f5c9dd8e044c1784ee194cb67a53d33 109 Hamap MF_02014 Cell division suppressor protein YneA [yneA]. 6 109 25.277 T 15-10-2018 IPR022887 Cell division suppressor protein, YneA C2I28_12270 1ab907dfff2137dda42b5576578aa043 228 Pfam PF04893 Yip1 domain 22 210 3.2E-23 T 15-10-2018 IPR006977 Yip1 domain GO:0016020 C2I28_24205 d89f8187bb1db7e56041cb3baa6524ea 154 Pfam PF13115 YtkA-like 31 111 2.1E-8 T 15-10-2018 IPR032693 YtkA-like domain C2I28_10420 375ce2db412ad1c6e0b8e7f113be8d76 201 Pfam PF09335 SNARE associated Golgi protein 30 156 2.6E-23 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_02705 8206d7e74d8fb9b727a96da216ecd5ab 342 Pfam PF13303 Phosphotransferase system, EIIC 28 335 5.0E-62 T 15-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 C2I28_23550 2fbd890c73a3c1dccd0be2a56542e56c 121 SUPERFAMILY SSF46458 7 116 3.32E-6 T 15-10-2018 IPR009050 Globin-like superfamily C2I28_12890 ae163070c1bb65b710724d97139becd3 124 Pfam PF09350 Domain of unknown function (DUF1992) 7 73 1.6E-20 T 15-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain C2I28_07305 419db55e9cf3fdbd2c79746ba3943ada 78 Pfam PF06612 Protein of unknown function (DUF1146) 17 64 1.4E-19 T 15-10-2018 IPR009526 Protein of unknown function DUF1146 C2I28_07305 419db55e9cf3fdbd2c79746ba3943ada 78 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 11 73 1.5E-22 T 15-10-2018 IPR009526 Protein of unknown function DUF1146 C2I28_22745 d332dabc869a0e0b92d7254aefdc8e3c 507 Pfam PF03806 AbgT putative transporter family 15 506 1.2E-186 T 15-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 C2I28_23650 caf8d94ceb572bc562e7c9acc6e8c2f3 238 Pfam PF02517 CAAX protease self-immunity 146 230 7.4E-19 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_18510 bbf41550486b9bbedea5c2bb3010683b 495 Pfam PF01593 Flavin containing amine oxidoreductase 12 483 4.1E-19 T 15-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 C2I28_18510 bbf41550486b9bbedea5c2bb3010683b 495 Gene3D G3DSA:3.50.50.60 3 93 5.0E-20 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18510 bbf41550486b9bbedea5c2bb3010683b 495 Gene3D G3DSA:3.50.50.60 186 334 2.1E-9 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_18510 bbf41550486b9bbedea5c2bb3010683b 495 SUPERFAMILY SSF51905 1 487 9.07E-50 T 15-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily C2I28_24210 9c06171c6b339dff8c2e664adaef300e 140 Pfam PF14040 Deoxyribonuclease NucA/NucB 44 138 1.2E-11 T 15-10-2018 IPR029476 Deoxyribonuclease NucA/NucB C2I28_11620 229c34eca0bf5b82488739455dc1d2d5 62 Pfam PF11151 Protein of unknown function (DUF2929) 1 54 9.4E-19 T 15-10-2018 IPR021324 Protein of unknown function DUF2929 C2I28_09525 7e51dbf407612ab7d3e8992828b4ef31 161 Pfam PF13058 Protein of unknown function (DUF3920) 24 154 6.5E-64 T 15-10-2018 IPR025033 Protein of unknown function DUF3920 C2I28_21880 5fda12385fb28d9a6dd7a663a5b7dd50 488 Pfam PF14436 Bacterial EndoU nuclease 351 475 1.1E-16 T 15-10-2018 IPR029501 Bacterial EndoU nuclease C2I28_21880 5fda12385fb28d9a6dd7a663a5b7dd50 488 Pfam PF14449 Pre-toxin TG 244 306 8.5E-16 T 15-10-2018 IPR027797 Pre-toxin TG domain C2I28_00320 1766fe003e27ef296513b98921421b7e 187 Pfam PF08006 Protein of unknown function (DUF1700) 1 181 1.9E-56 T 15-10-2018 IPR012963 Protein of unknown function DUF1700 C2I28_14225 23d2fd5ea7bb9208ea307b68379548db 451 Pfam PF02386 Cation transport protein 41 432 5.2E-62 T 15-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 C2I28_19125 6945b061853dcce16feed0c8311b5639 255 Pfam PF12730 ABC-2 family transporter protein 4 183 2.6E-18 T 15-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 C2I28_19740 6ac8c2798f55e4045936c4f07b8a4f97 435 Pfam PF03600 Citrate transporter 13 380 8.0E-48 T 15-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 C2I28_19740 6ac8c2798f55e4045936c4f07b8a4f97 435 TIGRFAM TIGR00784 citMHS: citrate transporter 2 435 3.1E-194 T 15-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 C2I28_04910 782eab0edf8b6295ed592b4f4a43fa09 360 Pfam PF05036 Sporulation related domain 184 250 3.2E-5 T 15-10-2018 IPR007730 Sporulation-like domain GO:0042834 C2I28_01685 d049a3bf291e481f0b775cae7d9315be 388 Pfam PF01098 Cell cycle protein 15 380 5.1E-97 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_26890 d5f5ce4732360dadb7bc7378b003d9d3 568 Pfam PF10592 AIPR protein 234 548 3.5E-35 T 15-10-2018 IPR018891 Abortive bacteriophage infection, resistance C2I28_15450 3a793c0cfee4bd3868b556a07c625d71 289 Pfam PF03773 Predicted permease 5 287 2.7E-77 T 15-10-2018 IPR005524 Predicted permease DUF318 C2I28_22070 3116de52a66ab2e1b2f89e07f1c7975b 140 Pfam PF14101 Domain of unknown function (DUF4275) 2 137 1.3E-45 T 15-10-2018 IPR025454 Protein of unknown function DUF4275 C2I28_25050 5046a9761f6cc916ff04a5bdb7201344 432 Gene3D G3DSA:3.40.50.11440 25 235 6.1E-9 T 15-10-2018 C2I28_25050 5046a9761f6cc916ff04a5bdb7201344 432 Pfam PF09861 Domain of unknown function (DUF2088) 23 189 3.0E-11 T 15-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 C2I28_23380 46872c9962eb5411c0d647ef63386176 187 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 3 178 1.9E-32 T 15-10-2018 IPR003740 Uncharacterised membrane protein YitT C2I28_14570 c5cbf7dabd1c76845602cf4d530964ad 122 Pfam PF03788 LrgA family 18 109 8.3E-30 T 15-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I28_10425 cf9da2d537db4af6b50cfe63d0956dfb 263 Pfam PF12787 EcsC protein family 10 254 7.8E-77 T 15-10-2018 IPR024787 EcsC protein C2I28_10425 cf9da2d537db4af6b50cfe63d0956dfb 263 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 10 257 6.0E-79 T 15-10-2018 C2I28_22080 d75a9964382447ddf02edc65b7e78746 204 Pfam PF02293 AmiS/UreI family transporter 1 164 4.4E-47 T 15-10-2018 IPR003211 AmiS/UreI transporter GO:0016020 C2I28_22080 d75a9964382447ddf02edc65b7e78746 204 Gene3D G3DSA:1.25.40.600 1 167 1.4E-40 T 15-10-2018 IPR038523 AmiS/UreI transporter superfamily C2I28_08270 46c08d87adfd56131dac8c6dd5866480 275 Pfam PF04468 PSP1 C-terminal conserved region 61 146 2.3E-31 T 15-10-2018 IPR007557 PSP1, C-terminal C2I28_26805 2b572a57638cfeed5387c627d137cd7f 148 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 14 145 4.5E-19 T 15-10-2018 IPR010106 Recombination-promoting nuclease RpnA C2I28_26805 2b572a57638cfeed5387c627d137cd7f 148 Pfam PF12784 PD-(D/E)XK nuclease family transposase 4 93 1.0E-9 T 15-10-2018 C2I28_26770 dbff0ee2ebe323e3fa6a9737f49e87fe 36 SUPERFAMILY SSF47406 4 32 1.83E-9 T 15-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 C2I28_26770 dbff0ee2ebe323e3fa6a9737f49e87fe 36 Pfam PF08671 Anti-repressor SinI 5 31 2.1E-14 T 15-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 C2I28_26770 dbff0ee2ebe323e3fa6a9737f49e87fe 36 Gene3D G3DSA:1.10.1660.10 5 36 6.9E-5 T 15-10-2018 C2I28_00665 345ce5becbb780a05c17e1084b8c1c64 179 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 21 164 4.2E-47 T 15-10-2018 IPR018697 Protein of unknown function DUF2199 C2I28_04170 8a1d1c414613d7a36e36c0ee31664247 260 Pfam PF06691 Protein of unknown function (DUF1189) 5 242 7.5E-37 T 15-10-2018 IPR009574 Protein of unknown function DUF1189 C2I28_11385 48b6a4a0b5e7d078b3ae980f38da3462 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 3.0E-28 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_21535 de66068c353007b7621caef8382b4276 210 Gene3D G3DSA:2.40.30.170 113 210 7.3E-21 T 15-10-2018 C2I28_21535 de66068c353007b7621caef8382b4276 210 SUPERFAMILY SSF51230 41 112 2.09E-11 T 15-10-2018 IPR011053 Single hybrid motif C2I28_21535 de66068c353007b7621caef8382b4276 210 Gene3D G3DSA:2.40.50.100 48 112 1.7E-12 T 15-10-2018 C2I28_21535 de66068c353007b7621caef8382b4276 210 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 32 165 8.0E-19 T 15-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain C2I28_11880 c3e22579c4f60db680ae61af4748e2c2 85 Pfam PF14069 Stage VI sporulation protein F 6 76 4.4E-28 T 15-10-2018 IPR025942 Stage VI sporulation protein F C2I28_16405 f3079a14eb107b7399e0ab6de4d88884 504 Pfam PF14269 Arylsulfotransferase (ASST) 129 377 6.6E-52 T 15-10-2018 IPR039535 Arylsulfotransferase-like C2I28_21210 0d35dd7162cce3890ae9f26b152a887b 306 Pfam PF01903 CbiX 138 242 1.3E-26 T 15-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I28_21210 0d35dd7162cce3890ae9f26b152a887b 306 Pfam PF01903 CbiX 9 114 9.1E-27 T 15-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 C2I28_21210 0d35dd7162cce3890ae9f26b152a887b 306 SUPERFAMILY SSF53800 1 249 3.49E-54 T 15-10-2018 C2I28_21210 0d35dd7162cce3890ae9f26b152a887b 306 Gene3D G3DSA:3.40.50.1400 127 250 1.0E-22 T 15-10-2018 C2I28_21210 0d35dd7162cce3890ae9f26b152a887b 306 Gene3D G3DSA:3.40.50.1400 1 124 1.6E-29 T 15-10-2018 C2I28_09750 9bb548f3a9eaff2f6e53e672f01f3556 351 Pfam PF06081 Aromatic acid exporter family member 1 10 147 7.1E-34 T 15-10-2018 IPR010343 Aromatic acid exporter family member 1 C2I28_04925 17ec4311f5e65b8dc775184bb34cec29 185 Pfam PF04238 Protein of unknown function (DUF420) 52 181 1.5E-42 T 15-10-2018 IPR007352 Protein of unknown function DUF420 C2I28_06685 6ef98f136085e0933960bd3ca531143b 237 Pfam PF03239 Iron permease FTR1 family 8 199 1.2E-30 T 15-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 C2I28_15515 d6dcd0bba15874fb9df82258681ceca5 131 Pfam PF10990 Protein of unknown function (DUF2809) 31 114 1.5E-27 T 15-10-2018 IPR021257 Protein of unknown function DUF2809 C2I28_16370 a1f78e5966454235467b38f385f9d946 397 Gene3D G3DSA:3.30.300.210 241 391 5.3E-39 T 15-10-2018 IPR038501 Spore germination GerAC superfamily C2I28_16370 a1f78e5966454235467b38f385f9d946 397 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 390 3.6E-91 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_16370 a1f78e5966454235467b38f385f9d946 397 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 225 388 1.1E-41 T 15-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 C2I28_19005 1fafe6f9fed8fb318286216736733f08 367 Pfam PF14907 Uncharacterised nucleotidyltransferase 35 252 2.0E-37 T 15-10-2018 IPR039498 Uncharacterised nucleotidyltransferase C2I28_16630 a4dc800ba6920a25e781a5bade6eaee7 348 Pfam PF03601 Conserved hypothetical protein 698 30 332 8.5E-79 T 15-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 C2I28_06260 a5ed63e295bd4f014f838e85bac3fa21 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 133 152 1.3E-14 T 15-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06260 a5ed63e295bd4f014f838e85bac3fa21 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 235 259 1.3E-14 T 15-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06260 a5ed63e295bd4f014f838e85bac3fa21 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.3E-14 T 15-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06260 a5ed63e295bd4f014f838e85bac3fa21 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 163 187 1.3E-14 T 15-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06260 a5ed63e295bd4f014f838e85bac3fa21 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.3E-14 T 15-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_06260 a5ed63e295bd4f014f838e85bac3fa21 494 Pfam PF00361 Proton-conducting membrane transporter 129 417 9.8E-52 T 15-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 C2I28_14585 638227a8c4b91c2b2e94a7b5ac4ae8eb 231 Pfam PF00583 Acetyltransferase (GNAT) family 28 146 8.4E-12 T 15-10-2018 IPR000182 GNAT domain C2I28_14585 638227a8c4b91c2b2e94a7b5ac4ae8eb 231 Gene3D G3DSA:3.40.630.30 8 229 5.0E-49 T 15-10-2018 C2I28_14585 638227a8c4b91c2b2e94a7b5ac4ae8eb 231 SUPERFAMILY SSF55729 18 151 1.25E-15 T 15-10-2018 IPR016181 Acyl-CoA N-acyltransferase C2I28_01425 35015b7723181f5bd2e2d68ae5b57740 98 Pfam PF17247 Family of unknown function (DUF5316) 29 95 8.8E-7 T 15-10-2018 IPR035167 Protein of unknown function DUF5316 C2I28_06640 4d58ae12052ec7bc7d119ba4cff4f690 57 Pfam PF13217 Protein of unknown function (DUF4025) 8 53 9.2E-18 T 15-10-2018 IPR025100 Protein of unknown function DUF4025 C2I28_15780 18d4296ecfb0e3d4407d9d324481677b 144 Gene3D G3DSA:1.20.1260.10 1 143 3.3E-46 T 15-10-2018 IPR012347 Ferritin-like C2I28_15780 18d4296ecfb0e3d4407d9d324481677b 144 Pfam PF00210 Ferritin-like domain 9 140 1.0E-25 T 15-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 C2I28_15780 18d4296ecfb0e3d4407d9d324481677b 144 SUPERFAMILY SSF47240 7 140 1.66E-29 T 15-10-2018 IPR009078 Ferritin-like superfamily C2I28_06770 831d5740c6c2397945d8a58b9f21a20b 159 Pfam PF07849 Protein of unknown function (DUF1641) 121 155 2.2E-14 T 15-10-2018 IPR012440 Protein of unknown function DUF1641 C2I28_26915 29bc982d169be3bcc64173056d80be83 520 TIGRFAM TIGR03236 dnd_assoc_1: DNA phosphorothioation-dependent restriction protein DptG 436 519 2.2E-13 T 15-10-2018 IPR017645 DNA phosphorothioation-dependent restriction protein DptG C2I28_20305 5cd15a0dd276f9cccf92afc326a7ba93 123 Pfam PF11042 Protein of unknown function (DUF2750) 13 116 1.6E-34 T 15-10-2018 IPR021284 Protein of unknown function DUF2750 C2I28_07250 98c76cd4810ca937b64d1a3fedda8c65 145 Pfam PF14183 YwpF-like protein 2 131 1.9E-41 T 15-10-2018 IPR025573 YwpF-like protein C2I28_22705 a5a245f0d3f8d369bb546c41778c9f86 424 Pfam PF01098 Cell cycle protein 98 414 2.2E-16 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 C2I28_04760 62c26c7de585bdd9b16db6e6a8f7e651 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 7.9E-24 T 15-10-2018 IPR021320 Protein of unknown function DUF2905 C2I28_05800 4e92128c874925055a1930990a3436bb 440 Pfam PF02447 GntP family permease 6 433 2.0E-10 T 15-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 C2I28_06205 75ea183b20ba5faf5da4966a883bd8b9 359 Pfam PF01384 Phosphate transporter family 18 308 8.5E-50 T 15-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 C2I28_22795 8496965e3da678e5a9ef7a02f00a0831 80 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.5E-22 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_19520 6a58706c7df7eeaf8ea8e69664be6d5a 65 Pfam PF14169 Cold-inducible protein YdjO 2 58 8.3E-27 T 15-10-2018 IPR025916 Cold-inducible protein YdjO C2I28_24910 c1dfcdc9c0f3ef193d74fef753b4fa61 235 Gene3D G3DSA:3.30.2010.10 137 229 8.7E-19 T 15-10-2018 C2I28_24910 c1dfcdc9c0f3ef193d74fef753b4fa61 235 Pfam PF01863 Protein of unknown function DUF45 22 227 1.4E-60 T 15-10-2018 IPR002725 Protein of unknown function DUF45 C2I28_03000 d2f6c3220dfc6514f731e20329cc4712 127 Pfam PF11877 Protein of unknown function (DUF3397) 10 118 8.2E-25 T 15-10-2018 IPR024515 Protein of unknown function DUF3397 C2I28_10085 8bd0501c97fa8221dd0d4314bb4b587f 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 180 5.3E-28 T 15-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase C2I28_10110 deb1b7fc99b5c665e61e6f0e5bf5fcd1 86 Pfam PF14182 YgaB-like protein 4 78 1.7E-31 T 15-10-2018 IPR025572 YgaB-like protein C2I28_01840 c0abd46d9d8d51772d8e7e40f1a372a1 83 Pfam PF10751 Protein of unknown function (DUF2535) 1 83 5.2E-40 T 15-10-2018 IPR019687 Protein of unknown function DUF2535 C2I28_05535 3ccbde36cab2b084b82ba9ac70395b93 232 Pfam PF11167 Protein of unknown function (DUF2953) 132 179 2.0E-17 T 15-10-2018 IPR021338 Protein of unknown function DUF2953 C2I28_15095 4dca641bc8b51fb167a5a3dcfa7d2e90 361 Pfam PF08757 CotH kinase protein 48 354 3.7E-80 T 15-10-2018 IPR014867 Spore coat protein CotH C2I28_07575 eae0e4ee4792babed16f702c6581edd2 224 Pfam PF13921 Myb-like DNA-binding domain 8 62 5.2E-5 T 15-10-2018 C2I28_07575 eae0e4ee4792babed16f702c6581edd2 224 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 78 6.0E-44 T 15-10-2018 IPR014243 Transcription factor, RsfA C2I28_18410 4be9fc136e201b9da4e7a0810e78107f 54 Pfam PF10055 Uncharacterized small protein (DUF2292) 9 44 8.1E-16 T 15-10-2018 IPR018743 Protein of unknown function DUF2292 C2I28_21370 8f704763eefa7413b5579c00848d15d9 108 Gene3D G3DSA:4.10.810.10 67 107 1.0E-5 T 15-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 C2I28_21370 8f704763eefa7413b5579c00848d15d9 108 Pfam PF08858 IDEAL domain 71 99 1.5E-7 T 15-10-2018 IPR014957 IDEAL domain C2I28_21370 8f704763eefa7413b5579c00848d15d9 108 SMART SM00914 57 99 1.2E-4 T 15-10-2018 IPR014957 IDEAL domain C2I28_27010 75b5ff2f2981771737675e8c65cf381e 73 Pfam PF11213 Protein of unknown function (DUF3006) 6 71 2.0E-17 T 15-10-2018 IPR021377 Protein of unknown function DUF3006 C2I28_15200 81995708c5efb1ef3bc1961adca5e374 208 Pfam PF04012 PspA/IM30 family 3 189 2.5E-16 T 15-10-2018 IPR007157 PspA/IM30 C2I28_25510 35349337b2d57910668212e0f4c7eff6 211 Pfam PF01810 LysE type translocator 13 201 2.0E-29 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_04275 c666d7ac89af38fecd82941f7a137801 267 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 58.393 T 15-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein C2I28_04275 c666d7ac89af38fecd82941f7a137801 267 Pfam PF03618 Kinase/pyrophosphorylase 6 261 3.7E-94 T 15-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 C2I28_05335 86254e285f01e91630d1bfb873fc1c4b 475 Pfam PF07261 Replication initiation and membrane attachment 332 397 1.5E-12 T 15-10-2018 IPR006343 DnaD domain C2I28_23925 16bac6e6d0cd433f545a191a160b818b 70 Pfam PF11148 Protein of unknown function (DUF2922) 2 68 3.8E-25 T 15-10-2018 IPR021321 Protein of unknown function DUF2922 C2I28_07550 70c0964bfe85ada3f0c5177cbada87ad 215 Pfam PF02163 Peptidase family M50 120 175 5.5E-8 T 15-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 C2I28_24585 a8a52c16d3531c5f67734f9a8affa37f 179 Pfam PF11193 Protein of unknown function (DUF2812) 20 113 7.0E-20 T 15-10-2018 IPR021359 Protein of unknown function DUF2812 C2I28_13665 62f9840f673ac757f6d4490f852a40d1 225 Pfam PF02397 Bacterial sugar transferase 31 216 1.5E-72 T 15-10-2018 IPR003362 Bacterial sugar transferase C2I28_07410 29b05a7a88e3fea5198c82e9c1c1a88b 297 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 5 167 2.6E-61 T 15-10-2018 IPR014202 Sporulation stage II, protein R C2I28_07410 29b05a7a88e3fea5198c82e9c1c1a88b 297 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 37 162 8.1E-47 T 15-10-2018 IPR014202 Sporulation stage II, protein R C2I28_23095 ac80c8445c532b3dff6c931b2bd3034f 317 Pfam PF07070 SpoOM protein 2 196 1.3E-47 T 15-10-2018 IPR009776 Sporulation stage 0, protein M C2I28_20890 ce81e587d72c7e33a981a253fc5820de 47 Pfam PF13040 Fur-regulated basic protein B 2 39 5.0E-14 T 15-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS C2I28_20230 f745bdb479768ea3a2a0a81b028f867c 71 Pfam PF04070 Domain of unknown function (DUF378) 2 56 3.2E-15 T 15-10-2018 IPR007211 Protein of unknown function DUF378 C2I28_02395 87823aa7bc53d8afb350f8ea8769f948 175 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 1 174 3.0E-10 T 15-10-2018 C2I28_01720 842fa926b7441372e9eddcafbb9672c3 353 Pfam PF10720 Protein of unknown function (DUF2515) 42 331 6.4E-110 T 15-10-2018 IPR019658 Protein of unknown function DUF2515 C2I28_21080 704d4e997e3f3a8df1b87a1002c07347 104 Pfam PF01235 Sodium:alanine symporter family 6 77 2.1E-16 T 15-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 C2I28_03275 7e314bd372ad6ea060e2dc7ec557dcbe 45 Pfam PF14140 YpzI-like protein 1 41 1.4E-27 T 15-10-2018 IPR025414 YpzI-like protein C2I28_00160 5c47fbb578b351c1e8432c7319bfdad5 121 Pfam PF09862 Protein of unknown function (DUF2089) 9 119 2.5E-44 T 15-10-2018 IPR018658 Protein of unknown function DUF2089 C2I28_10565 80de3e9e39fbe445613a8b70250da6e4 163 Pfam PF11181 Heat induced stress protein YflT 6 122 8.3E-18 T 15-10-2018 IPR025889 General stress protein 17M-like domain C2I28_19470 b71ae428485ae1d5b5f168aa5317de1d 68 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 5 67 2.1E-29 T 15-10-2018 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon C2I28_13255 2cf8f7726ed5fc3a97da4cebd9f19dee 197 Pfam PF16291 Domain of unknown function (DUF4937 2 88 1.2E-34 T 15-10-2018 IPR032555 Domain of unknown function DUF4937 C2I28_13255 2cf8f7726ed5fc3a97da4cebd9f19dee 197 SUPERFAMILY SSF54909 1 77 2.41E-8 T 15-10-2018 IPR011008 Dimeric alpha-beta barrel C2I28_04725 62c867c1c4577517244f4b3f216e2663 97 Pfam PF13797 Post-transcriptional regulator 9 83 2.7E-28 T 15-10-2018 IPR025716 Post-transcriptional regulator C2I28_06975 7de76985afa7a00e313975002070468f 103 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 46 2.0E-12 T 15-10-2018 C2I28_02480 9078ba6aa48f2821c2a650b7442d6d2d 143 Pfam PF03748 Flagellar basal body-associated protein FliL 53 143 1.5E-11 T 15-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 C2I28_06285 5079342846e8165b6b9976a23105cade 76 Pfam PF04070 Domain of unknown function (DUF378) 4 61 5.8E-27 T 15-10-2018 IPR007211 Protein of unknown function DUF378 C2I28_14945 1b0da2e4243e80f3efb161d7a2cd5bf0 258 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 27 251 2.9E-65 T 15-10-2018 IPR014231 Sporulation protein YpjB C2I28_05655 0f79c186430123a9a422cd5ba85e78e2 151 Pfam PF12732 YtxH-like protein 17 98 7.4E-20 T 15-10-2018 IPR024623 Uncharacterised protein family YtxH C2I28_02715 c99ed4062f214f9af1bb3b062dda7046 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 1.9E-37 T 15-10-2018 IPR005531 Alkaline shock protein Asp23 C2I28_06490 2fe301385cab0d36886718daa485a60a 38 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 28 5.1E-7 T 15-10-2018 IPR031596 Putative methionine and alanine importer, small subunit C2I28_07205 ea87f8ef58894d3937142d2ab31cb371 177 Gene3D G3DSA:2.40.50.140 89 171 1.8E-27 T 15-10-2018 C2I28_03800 5fcc9bc89766bac71ea259a4efceb659 50 Pfam PF14174 YycC-like protein 1 49 7.0E-28 T 15-10-2018 IPR025550 YycC-like protein C2I28_05420 da8dd9acc0dbe3fb955ec75328869abb 136 Pfam PF04186 FxsA cytoplasmic membrane protein 14 119 6.7E-33 T 15-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 C2I28_04290 1262e676d2c737210d2cc03ebd2ce6a5 47 Pfam PF14006 YqzL-like protein 3 45 9.6E-17 T 15-10-2018 IPR025617 YqzL-like protein C2I28_09685 53f109269357fc4692b58b97f9ec2d19 404 Pfam PF04235 Protein of unknown function (DUF418) 229 381 8.0E-40 T 15-10-2018 IPR007349 Domain of unknown function DUF418 C2I28_16275 8f26b6eab6f529b2aee89476e3287fd3 393 Gene3D G3DSA:3.30.420.40 208 350 2.1E-5 T 15-10-2018 C2I28_13610 92e8ede9c0712bd153c6d3198ba48b00 185 Pfam PF04982 HPP family 67 181 3.5E-29 T 15-10-2018 IPR007065 HPP C2I28_19440 e84370c1330f074f65648235d291ae52 192 Pfam PF09335 SNARE associated Golgi protein 30 154 1.3E-13 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_10040 26655ba1e7c2625e6098824a943b94ad 38 Pfam PF14152 YfhE-like protein 3 38 3.3E-21 T 15-10-2018 IPR025437 YfhE-like protein C2I28_04105 92400f24a0181e5bb484c6ee31f2fd15 164 Pfam PF16258 Domain of unknown function (DUF4912) 17 121 1.5E-15 T 15-10-2018 IPR032585 Protein of unknown function DUF4912 C2I28_27495 fe4124c012195aeef5c98850c3a1f555 226 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 12 181 4.7E-27 T 15-10-2018 IPR014903 Protein of unknown function DUF1796 C2I28_25910 22eaf4e453adcd2896ef5eacf0753e2d 66 Pfam PF14169 Cold-inducible protein YdjO 1 59 7.0E-23 T 15-10-2018 IPR025916 Cold-inducible protein YdjO C2I28_16030 e827fc15841c2a9a740db335aee0523b 473 Pfam PF03606 C4-dicarboxylate anaerobic carrier 23 466 1.5E-109 T 15-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 C2I28_25900 02b8a52c1260dd07ddf14c393c3bf054 303 SUPERFAMILY SSF57997 47 194 6.54E-7 T 15-10-2018 C2I28_03105 2a35f706be2564e27788f685046f49aa 78 Pfam PF14003 YlbE-like protein 13 73 5.2E-30 T 15-10-2018 IPR025613 YlbE-like protein C2I28_01155 6c3767a676e0dffd05ecf90af9856c1e 313 Pfam PF13536 Putative multidrug resistance efflux transporter 38 296 1.4E-105 T 15-10-2018 IPR032713 Putative multidrug resistance efflux transporter C2I28_25500 29cfeba05d6834422221d0ce316ee01f 146 ProDom PD086672 YXAJ MEMBRANE TRANSMEMBRANE 9 137 2.0E-18 T 15-10-2018 IPR020204 Uncharacterised protein family, YxaJ C2I28_25500 29cfeba05d6834422221d0ce316ee01f 146 Pfam PF17369 Family of unknown function (DUF5391) 2 136 2.7E-39 T 15-10-2018 IPR020204 Uncharacterised protein family, YxaJ C2I28_15535 6f9c3c363120826ba109311036ec3d5f 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 3.2E-22 T 15-10-2018 IPR019618 Spore germination protein GerPA/GerPF C2I28_14875 aa75c937ff2d42d49f339fcd9356faab 166 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 5 165 2.0E-49 T 15-10-2018 IPR020229 Uncharacterised protein YlaL C2I28_03880 3e101a5dd492301defd660306bc9f075 220 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 30 219 4.7E-64 T 15-10-2018 IPR014195 Sporulation stage III, protein AG C2I28_07355 88eb124d0a7fb772afe04d5b134fad60 73 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 12 64 1.1E-14 T 15-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter C2I28_27465 eb22e4f8855525e4c4eb20f75eed26d6 207 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 12 164 5.8E-26 T 15-10-2018 IPR014903 Protein of unknown function DUF1796 C2I28_13015 6a9bb5a390bb8ea891a21b11241f5729 202 Pfam PF09335 SNARE associated Golgi protein 47 161 3.9E-15 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_11585 486102aed0c6ba38b944888118f2285e 59 Pfam PF14168 YjzC-like protein 1 55 1.5E-28 T 15-10-2018 IPR025549 YjzC-like protein C2I28_07150 64bafd7d8a16d33745921d6d5b2effc1 137 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 4 136 5.8E-43 T 15-10-2018 IPR022258 Flagellar operon protein YvyF C2I28_24420 b337b1a0bc05aa601399289505c37b23 88 Pfam PF05800 Gas vesicle synthesis protein GvpO 7 81 1.7E-8 T 15-10-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 C2I28_21915 41e7aae4d4409af9e17137ac2b86e6d3 90 Pfam PF17279 Family of unknown function (DUF5344) 3 87 1.7E-19 T 15-10-2018 C2I28_16855 807c24bfa7dd4d14786ab1c1b628e948 236 Pfam PF02517 CAAX protease self-immunity 129 217 3.0E-16 T 15-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 C2I28_25885 54383b5e246709944d66b8c74348c2a0 396 Pfam PF12770 CHAT domain 233 390 9.9E-7 T 15-10-2018 IPR024983 CHAT domain C2I28_01335 4e2f5192d10c89d71ead06364983ac17 408 Pfam PF05684 Protein of unknown function (DUF819) 16 406 1.3E-98 T 15-10-2018 IPR008537 Protein of unknown function DUF819 C2I28_22990 11f1c9199366c0bf257d1821464429e7 197 Pfam PF09335 SNARE associated Golgi protein 32 157 5.5E-19 T 15-10-2018 IPR032816 SNARE associated Golgi protein C2I28_24800 82f00fb4c6ad26162c02ea86d38565d7 456 Pfam PF10011 Predicted membrane protein (DUF2254) 24 391 1.4E-92 T 15-10-2018 IPR018723 Protein of unknown function DUF2254, membrane C2I28_16220 6a2675d2fea035b7cf2408215b891033 165 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 9 148 3.2E-25 T 15-10-2018 IPR018639 Domain of unknown function DUF2062 C2I28_26555 0b96556bbc44433a384ec1b42964d0f6 361 Pfam PF13222 Protein of unknown function (DUF4030) 223 359 2.0E-11 T 15-10-2018 IPR025108 Protein of unknown function DUF4030 C2I28_23625 aa647aa084ccdbfd3bfb72ef4a52899b 123 SUPERFAMILY SSF48371 4 120 4.89E-5 T 15-10-2018 IPR016024 Armadillo-type fold C2I28_23890 5c0fce130deddca33c58e07e64d863e1 252 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 22 244 2.0E-56 T 15-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related C2I28_18660 f6f0b46ff0882425fc825b972942b662 76 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 18 74 9.4E-24 T 15-10-2018 IPR018690 Protein of unknown function DUF2187 C2I28_26050 addae9d878b083e8cf92105273c3655a 223 Pfam PF16161 Domain of unknown function (DUF4867) 17 219 2.9E-82 T 15-10-2018 IPR032358 Protein of unknown function DUF4867 C2I28_12940 aba636ee662385b6dad39f1df37baea5 57 Pfam PF13113 Protein of unknown function (DUF3970) 1 54 1.5E-29 T 15-10-2018 IPR025088 Protein of unknown function DUF3970 C2I28_13280 d935658b5ff1e4ecb1f5e67d2ed4c5f9 117 Pfam PF13789 Domain of unknown function (DUF4181) 12 112 1.7E-14 T 15-10-2018 IPR025441 Protein of unknown function DUF4181 C2I28_21075 dd6aa0afe5272f94d0521c90aff5f67f 120 Pfam PF02656 Domain of unknown function (DUF202) 13 84 6.4E-14 T 15-10-2018 IPR003807 Domain of unknown function DUF202 C2I28_03415 c78a897873a2ad97064a24e139083a59 540 Pfam PF05140 ResB-like family 64 429 3.2E-77 T 15-10-2018 IPR007816 ResB-like domain C2I28_03415 c78a897873a2ad97064a24e139083a59 540 Pfam PF05140 ResB-like family 443 519 3.4E-17 T 15-10-2018 IPR007816 ResB-like domain C2I28_12080 cd0bacd700de4f3ae2360bc12ee7d112 144 Pfam PF03788 LrgA family 21 112 7.9E-26 T 15-10-2018 IPR005538 LrgA/CidA family GO:0016021 C2I28_17645 9529a32ce34d2d41339ad79c38e6b09c 74 Pfam PF13031 Protein of unknown function (DUF3892) 5 72 5.0E-15 T 15-10-2018 IPR024997 Protein of unknown function DUF3892 C2I28_03860 a29089d81f85b79f1a999a095300db8f 133 Pfam PF03780 Asp23 family, cell envelope-related function 16 121 6.9E-36 T 15-10-2018 IPR005531 Alkaline shock protein Asp23 C2I28_16505 d6902416dd9ef377046778e2d38ecb06 66 Pfam PF06906 Protein of unknown function (DUF1272) 2 55 3.4E-22 T 15-10-2018 IPR010696 Protein of unknown function DUF1272 C2I28_14055 0eb483ab42adef5ad2149188f6ea0f0b 250 Pfam PF01863 Protein of unknown function DUF45 24 72 2.5E-5 T 15-10-2018 IPR002725 Protein of unknown function DUF45 C2I28_14055 0eb483ab42adef5ad2149188f6ea0f0b 250 Pfam PF01863 Protein of unknown function DUF45 81 222 1.4E-16 T 15-10-2018 IPR002725 Protein of unknown function DUF45 C2I28_24560 fe459261d8fe05925d64ed5cdc3fa565 647 PIRSF PIRSF018968 1 647 7.9E-154 T 15-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 C2I28_26115 0714cc64d1712271be600f2e4a969421 392 Pfam PF04235 Protein of unknown function (DUF418) 228 379 3.9E-39 T 15-10-2018 IPR007349 Domain of unknown function DUF418 C2I28_22545 a853fa4eff009fd6c1cb4be2a7cba690 113 Pfam PF06279 Protein of unknown function (DUF1033) 5 107 2.3E-25 T 15-10-2018 IPR010434 Protein of unknown function DUF1033 C2I28_26820 6679608504011f63b3edbc36ff88b2a7 394 Gene3D G3DSA:3.30.420.40 208 350 5.0E-5 T 15-10-2018 C2I28_10080 87dad78bcd089dabe40954e6a14763a0 89 Pfam PF14043 WVELL protein 3 76 4.1E-38 T 15-10-2018 IPR026952 WVELL protein C2I28_09995 24a098801cb3707453974a897b9a01c2 266 Pfam PF14167 YfkD-like protein 35 266 3.3E-112 T 15-10-2018 IPR025548 YfkD-like protein C2I28_03890 cb284554efb9dc496359660acfb74763 394 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 1 386 1.1E-152 T 15-10-2018 IPR014194 Sporulation stage III, protein AE C2I28_03890 cb284554efb9dc496359660acfb74763 394 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 72 386 1.8E-110 T 15-10-2018 IPR014194 Sporulation stage III, protein AE C2I28_23600 96df596e262574d205a353a549561fdc 60 Pfam PF08863 YolD-like protein 5 59 2.8E-8 T 15-10-2018 IPR014962 YolD-like protein C2I28_18805 ca6945c5ed29b5e27d0f74cf7a2e7ee2 261 Pfam PF10127 Predicted nucleotidyltransferase 1 254 1.7E-85 T 15-10-2018 IPR018775 Nucleotidyltransferase, predicted C2I28_05235 35dbf8de559e15c90a63de0e80ce7302 135 Pfam PF03994 Domain of Unknown Function (DUF350) 80 134 4.6E-15 T 15-10-2018 IPR007140 Protein of unknown function DUF350 C2I28_05235 35dbf8de559e15c90a63de0e80ce7302 135 Pfam PF03994 Domain of Unknown Function (DUF350) 15 68 9.7E-13 T 15-10-2018 IPR007140 Protein of unknown function DUF350 C2I28_25105 8f526002febba54d15d26d226dbf0194 91 Pfam PF13828 Domain of unknown function (DUF4190) 13 71 1.8E-13 T 15-10-2018 IPR025241 Domain of unknown function DUF4190 C2I28_15065 a4f3a2bc9b83c2e226ae05b74e8bb44e 330 Pfam PF10720 Protein of unknown function (DUF2515) 19 316 8.9E-115 T 15-10-2018 IPR019658 Protein of unknown function DUF2515 C2I28_15840 281dce8ff83adb8a70615b542e5cd28b 50 Pfam PF14139 YpzG-like protein 1 49 1.1E-22 T 15-10-2018 IPR025413 YpzG-like protein C2I28_25485 c652144482691787d9db170d7d4d3bbb 76 Pfam PF13129 Protein of unknown function (DUF3953) 34 72 2.8E-11 T 15-10-2018 IPR025018 Protein of unknown function DUF3953 C2I28_02035 a8c808efb5e39da2ec68ceaa1c22a548 131 Pfam PF04138 GtrA-like protein 6 118 5.6E-26 T 15-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 C2I28_04545 2b9ca5c544f0740dd6a91eccf0fa2ef3 216 Pfam PF07423 Protein of unknown function (DUF1510) 8 215 5.9E-55 T 15-10-2018 IPR009988 Protein of unknown function DUF1510 C2I28_03110 6162a4f28954c7edf8e3ad9a132b41a9 136 Pfam PF14071 Putative coat protein 14 136 1.1E-41 T 15-10-2018 IPR025953 Putative coat protein YlbD C2I28_12655 9d979043c465dfb5413148bf7ece3d9b 61 Pfam PF12669 Virus attachment protein p12 family 3 45 6.2E-9 T 15-10-2018 C2I28_04160 9564b44c646807a766ce2a299ff07961 161 Pfam PF04306 Protein of unknown function (DUF456) 21 159 1.4E-38 T 15-10-2018 IPR007403 Protein of unknown function DUF456 C2I28_15830 9356c553da95c7e03a729ba88abb2af4 207 Pfam PF01810 LysE type translocator 12 199 3.4E-35 T 15-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 C2I28_13590 cc88b138772a3eff7131418b05ff1c1a 321 Pfam PF06166 Protein of unknown function (DUF979) 9 319 5.6E-124 T 15-10-2018 IPR009323 Protein of unknown function DUF979 C2I28_16230 5e5709727fb8388b3cf8eb1f2e141ec0 70 Pfam PF01098 Cell cycle protein 1 52 3.6E-16 T 15-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471