locus-tag	class	description
CHR53_00010	COG0592	DNA-directed DNA polymerase activity
CHR53_00015	COG2501	S4 domain
CHR53_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR53_00030	COG0187	DNA topoisomerase II activity
CHR53_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHR53_00075	COG0517	IMP dehydrogenase activity
CHR53_00075	COG0516	GMP reductase activity
CHR53_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CHR53_00105	COG1428	Deoxynucleoside kinase
CHR53_00110	COG1428	Deoxynucleoside kinase
CHR53_00115	COG1388	LysM domain
CHR53_00115	COG3858	chitin binding
CHR53_00120	COG1335	isochorismatase
CHR53_00125	COG0590	tRNA wobble adenosine to inosine editing
CHR53_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHR53_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHR53_00190	COG1982	Orn Lys Arg decarboxylase major
CHR53_00195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHR53_00200	COG3870	Protein conserved in bacteria
CHR53_00205	COG0470	DNA polymerase III
CHR53_00210	COG1774	PSP1 C-terminal conserved region
CHR53_00215	COG4467	Involved in initiation control of chromosome replication
CHR53_00220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CHR53_00225	COG2827	Endonuclease containing a URI domain
CHR53_00230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHR53_00235	COG2002	toxin-antitoxin pair type II binding
CHR53_00245	COG0084	hydrolase, TatD family'
CHR53_00250	COG3583	domain protein
CHR53_00250	COG3584	3D domain protein
CHR53_00260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHR53_00270	COG4466	Protein conserved in bacteria
CHR53_00285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR53_00290	COG0251	oxidation-reduction process
CHR53_00295	COG2088	sporulation resulting in formation of a cellular spore
CHR53_00300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHR53_00305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHR53_00310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CHR53_00315	COG0193	aminoacyl-tRNA hydrolase activity
CHR53_00325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHR53_00330	COG2002	toxin-antitoxin pair type II binding
CHR53_00335	COG2244	polysaccharide biosynthetic process
CHR53_00340	COG3956	TIGRFAM MazG family protein
CHR53_00345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHR53_00365	COG1098	S1 RNA binding domain
CHR53_00370	COG2208	phosphoserine phosphatase activity
CHR53_00375	COG2304	oxidoreductase activity
CHR53_00380	COG0515	serine threonine protein kinase
CHR53_00395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR53_00400	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CHR53_00405	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHR53_00410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHR53_00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHR53_00420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHR53_00425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHR53_00430	COG1396	sequence-specific DNA binding
CHR53_00435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHR53_00440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHR53_00530	COG3880	PFAM UvrB UvrC protein
CHR53_00535	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CHR53_00540	COG0542	response to heat
CHR53_00545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHR53_00555	COG4956	integral membrane protein (PIN domain superfamily)
CHR53_00560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CHR53_00565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CHR53_00570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHR53_00575	COG1045	serine acetyltransferase
CHR53_00580	COG0215	cysteine-tRNA ligase activity
CHR53_00590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR53_00595	COG3688	RNA-binding protein containing a PIN domain
CHR53_00605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHR53_00610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHR53_00615	COG0250	Participates in transcription elongation, termination and antitermination
CHR53_00625	COG0081	regulation of translation
CHR53_00630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHR53_00635	COG0222	ribosome binding
CHR53_00640	COG2813	Specifically methylates the guanine in position
CHR53_00650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHR53_00655	COG1358	cellular component organization or biogenesis
CHR53_00660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHR53_00665	COG0049	tRNA binding
CHR53_00670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHR53_00675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHR53_00680	COG0051	transcription antitermination factor activity, RNA binding
CHR53_00685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHR53_00690	COG0088	Forms part of the polypeptide exit tunnel
CHR53_00700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHR53_00705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHR53_00710	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHR53_00715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHR53_00720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHR53_00725	COG0255	Belongs to the universal ribosomal protein uL29 family
CHR53_00735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHR53_00740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHR53_00745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHR53_00755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHR53_00760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHR53_00765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHR53_00770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHR53_00775	COG1841	ribosomal large subunit assembly
CHR53_00780	COG0200	Binds to the 23S rRNA
CHR53_00785	COG0201	protein transport
CHR53_00790	COG0563	adenylate kinase activity
CHR53_00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHR53_00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHR53_00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHR53_00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHR53_00815	COG0202	RNA polymerase activity
CHR53_00820	COG0203	ribosomal protein L17
CHR53_00825	COG1122	ATPase activity
CHR53_00830	COG1122	ATPase activity
CHR53_00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHR53_00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHR53_00850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CHR53_00895	COG2197	response regulator
CHR53_00900	COG2203	Gaf domain
CHR53_00900	COG4585	Histidine kinase
CHR53_00910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHR53_00915	COG0300	oxidoreductase activity
CHR53_00920	COG1609	Transcriptional regulator
CHR53_00925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR53_00935	COG0697	spore germination
CHR53_00965	COG0477	Major facilitator Superfamily
CHR53_01000	COG1396	sequence-specific DNA binding
CHR53_01015	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_01030	COG3069	C4-dicarboxylate transmembrane transporter activity
CHR53_01040	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHR53_01045	COG0489	protein tyrosine kinase activity
CHR53_01055	COG2194	sulfuric ester hydrolase activity
CHR53_01060	COG0726	polysaccharide deacetylase
CHR53_01135	COG1609	Transcriptional regulator
CHR53_01140	COG1077	Cell shape determining protein MreB Mrl
CHR53_01150	COG1595	DNA-templated transcription, initiation
CHR53_01155	COG5662	AntiSigma factor
CHR53_01160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CHR53_01165	COG4856	YbbR-like protein
CHR53_01170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR53_01175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHR53_01180	COG3162	membrane
CHR53_01185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_01195	COG2259	Doxx family
CHR53_01200	COG0346	lactoylglutathione lyase activity
CHR53_01215	COG1404	Belongs to the peptidase S8 family
CHR53_01220	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CHR53_01225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR53_01225	COG2213	PTS system mannitol-specific
CHR53_01230	COG3711	transcriptional antiterminator
CHR53_01235	COG0246	Mannitol dehydrogenase
CHR53_01240	COG2309	aminopeptidase activity
CHR53_01255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_01260	COG1131	(ABC) transporter
CHR53_01275	COG3829	transcription factor binding
CHR53_01280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHR53_01285	COG0833	amino acid
CHR53_01300	COG1388	LysM domain
CHR53_01300	COG3858	chitin binding
CHR53_01305	COG3511	phospholipase C
CHR53_01310	COG0655	NAD(P)H dehydrogenase (quinone) activity
CHR53_01315	COG0583	DNA-binding transcription factor activity
CHR53_01350	COG2062	phosphohistidine phosphatase, SixA
CHR53_01360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHR53_01370	COG3328	transposase activity
CHR53_01380	COG3030	protein affecting phage T7 exclusion by the F plasmid
CHR53_01385	COG0693	protein deglycase activity
CHR53_01400	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CHR53_01430	COG0346	lactoylglutathione lyase activity
CHR53_01445	COG2318	DinB family
CHR53_01450	COG4555	ABC transporter
CHR53_01490	COG0697	spore germination
CHR53_01495	COG1309	transcriptional regulator
CHR53_01510	COG0018	arginyl-trna synthetase
CHR53_01520	COG2814	Major facilitator Superfamily
CHR53_01525	COG2076	Multidrug Resistance protein
CHR53_01530	COG2076	Multidrug Resistance protein
CHR53_01535	COG0586	Pfam SNARE associated Golgi protein
CHR53_01540	COG0772	Belongs to the SEDS family
CHR53_01545	COG2239	Acts as a magnesium transporter
CHR53_01555	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHR53_01560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHR53_01565	COG0513	Belongs to the DEAD box helicase family
CHR53_01585	COG0697	spore germination
CHR53_01590	COG3402	PFAM membrane-flanked domain
CHR53_01595	COG3428	Bacterial PH domain
CHR53_01600	COG0705	Rhomboid family
CHR53_01605	COG0736	holo-[acyl-carrier-protein] synthase activity
CHR53_01610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CHR53_01620	COG0864	Transcriptional regulator
CHR53_01625	COG2337	Toxic component of a toxin-antitoxin (TA) module
CHR53_01630	COG2183	response to ionizing radiation
CHR53_01640	COG3091	SprT-like family
CHR53_01715	COG0802	atpase or kinase
CHR53_01720	COG1214	PFAM Peptidase M22, glycoprotease
CHR53_01725	COG0456	acetyltransferase
CHR53_01735	COG0488	(ABC) transporter
CHR53_01740	COG0315	cyclic pyranopterin monophosphate synthase activity
CHR53_01745	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CHR53_01755	COG1266	CAAX protease self-immunity
CHR53_01760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHR53_01765	COG0459	protein refolding
CHR53_01770	COG4974	Belongs to the 'phage' integrase family
CHR53_01905	COG0745	RESPONSE REGULATOR receiver
CHR53_01910	COG5002	protein histidine kinase activity
CHR53_01935	COG0501	Belongs to the peptidase M48B family
CHR53_01940	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR53_01945	COG1278	Cold shock
CHR53_01960	COG1733	regulation of RNA biosynthetic process
CHR53_01965	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_01980	COG1131	(ABC) transporter
CHR53_02025	COG2508	Transcriptional regulator
CHR53_02040	COG0145	ligase activity
CHR53_02135	COG2204	response regulator
CHR53_02145	COG0028	Belongs to the TPP enzyme family
CHR53_02155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHR53_02160	COG0833	amino acid
CHR53_02170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_02175	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_02185	COG4294	response to UV
CHR53_02210	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR53_02215	COG3842	ATPase activity
CHR53_02240	COG1349	DNA-binding transcription factor activity
CHR53_02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_02260	COG0657	acetylesterase activity
CHR53_02265	COG4638	Rieske (2fe-2S)
CHR53_02270	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_02275	COG0473	3-isopropylmalate dehydrogenase activity
CHR53_02280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CHR53_02290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_02295	COG0714	Associated with various cellular activities
CHR53_02300	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CHR53_02305	COG1305	Transglutaminase-like
CHR53_02310	COG0519	Catalyzes the synthesis of GMP from XMP
CHR53_02310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CHR53_02315	COG3328	transposase activity
CHR53_02320	COG2252	PERMEase
CHR53_02325	COG1131	(ABC) transporter
CHR53_02330	COG0842	Transport permease protein
CHR53_02330	COG1511	domain protein
CHR53_02335	COG0842	Transport permease protein
CHR53_02340	COG3711	transcriptional antiterminator
CHR53_02345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR53_02345	COG1263	PTS System
CHR53_02345	COG2190	(PTS) system
CHR53_02380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHR53_02385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHR53_02390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHR53_02395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHR53_02400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHR53_02405	COG0047	phosphoribosylformylglycinamidine synthase activity
CHR53_02410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHR53_02415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHR53_02420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHR53_02425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHR53_02435	COG0151	Belongs to the GarS family
CHR53_02445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR53_02450	COG1470	cell adhesion involved in biofilm formation
CHR53_02455	COG4496	protein, YerC YecD
CHR53_02460	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CHR53_02465	COG0210	DNA helicase
CHR53_02470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHR53_02475	COG4851	CamS sex pheromone cAM373 precursor
CHR53_02480	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_02505	COG1404	Belongs to the peptidase S8 family
CHR53_02505	COG4412	M6 family metalloprotease domain protein
CHR53_02515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_02535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CHR53_02540	COG2224	Isocitrate lyase
CHR53_02545	COG3104	oligopeptide transport
CHR53_02550	COG5506	Protein of unknown function (DUF1694)
CHR53_02560	COG0741	lytic transglycosylase activity
CHR53_02565	COG1764	response to oxidative stress
CHR53_02575	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR53_02580	COG0154	amidase activity
CHR53_02590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_02605	COG2226	methyltransferase
CHR53_02610	COG1126	abc transporter atp-binding protein
CHR53_02615	COG0765	amino acid transport
CHR53_02620	COG0765	amino acid transport
CHR53_02630	COG1595	DNA-templated transcription, initiation
CHR53_02650	COG1597	lipid kinase activity
CHR53_02655	COG1335	isochorismatase
CHR53_02660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHR53_02665	COG0733	neurotransmitter:sodium symporter activity
CHR53_02680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR53_02720	COG0210	DNA helicase
CHR53_02755	COG0668	transmembrane transport
CHR53_02760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHR53_02770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR53_02790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHR53_02800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_02820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_02835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHR53_02840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR53_02845	COG1120	ATPase activity
CHR53_02855	COG1819	glycosyl
CHR53_02865	COG0791	NLP P60 protein
CHR53_02865	COG3103	Sh3 type 3 domain protein
CHR53_02865	COG1388	LysM domain
CHR53_02870	COG3227	Zinc metalloprotease (Elastase)
CHR53_02875	COG0436	Aminotransferase
CHR53_02880	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CHR53_02885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CHR53_02895	COG0833	amino acid
CHR53_02900	COG0824	Thioesterase
CHR53_02910	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_02950	COG0697	spore germination
CHR53_02955	COG2814	Major facilitator Superfamily
CHR53_02960	COG0583	DNA-binding transcription factor activity
CHR53_02965	COG0730	response to heat
CHR53_02990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR53_02995	COG0765	amino acid transport
CHR53_03005	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHR53_03025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHR53_03030	COG0346	lactoylglutathione lyase activity
CHR53_03035	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CHR53_03050	COG0386	Belongs to the glutathione peroxidase family
CHR53_03055	COG2936	dipeptidyl-peptidase activity
CHR53_03065	COG0765	amino acid transport
CHR53_03070	COG1126	abc transporter atp-binding protein
CHR53_03075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHR53_03085	COG0589	response to stress
CHR53_03100	COG1126	abc transporter atp-binding protein
CHR53_03105	COG0765	amino acid transport
CHR53_03110	COG0765	amino acid transport
CHR53_03115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR53_03120	COG1960	acyl-CoA dehydrogenase activity
CHR53_03125	COG0109	protoheme IX farnesyltransferase activity
CHR53_03130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR53_03140	COG2190	(PTS) system
CHR53_03145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR53_03145	COG1263	PTS System
CHR53_03150	COG3711	transcriptional antiterminator
CHR53_03165	COG3279	Response regulator of the LytR AlgR family
CHR53_03170	COG0427	acetyl-CoA hydrolase
CHR53_03175	COG0406	alpha-ribazole phosphatase activity
CHR53_03190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR53_03195	COG4605	iron ion homeostasis
CHR53_03200	COG4604	ABC transporter, ATP-binding protein
CHR53_03205	COG4607	ABC-type enterochelin transport system periplasmic component
CHR53_03210	COG5002	protein histidine kinase activity
CHR53_03215	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CHR53_03225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR53_03230	COG0805	protein transport
CHR53_03240	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CHR53_03245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR53_03285	COG0733	neurotransmitter:sodium symporter activity
CHR53_03290	COG1268	BioY protein
CHR53_03295	COG2199	diguanylate cyclase activity
CHR53_03300	COG1115	amino acid carrier protein
CHR53_03305	COG0590	tRNA wobble adenosine to inosine editing
CHR53_03310	COG0656	L-ascorbic acid biosynthetic process
CHR53_03320	COG1131	(ABC) transporter
CHR53_03335	COG1414	Transcriptional regulator
CHR53_03340	COG1834	amidinotransferase
CHR53_03350	COG4187	Peptidase family M20/M25/M40
CHR53_03355	COG0833	amino acid
CHR53_03360	COG1823	symporter activity
CHR53_03395	COG3209	COG3209 Rhs family protein
CHR53_03420	COG1442	glycosyl transferase family 8
CHR53_03430	COG1442	glycosyl transferase family 8
CHR53_03440	COG1595	DNA-templated transcription, initiation
CHR53_03450	COG0436	Aminotransferase
CHR53_03455	COG1522	sequence-specific DNA binding
CHR53_03460	COG1473	amidohydrolase
CHR53_03465	COG1288	antiporter activity
CHR53_03480	COG0583	DNA-binding transcription factor activity
CHR53_03530	COG0613	PHP domain protein
CHR53_03535	COG0463	Glycosyl transferase, family 2
CHR53_03550	COG0730	response to heat
CHR53_03555	COG0529	Catalyzes the synthesis of activated sulfate
CHR53_03580	COG0189	ligase activity
CHR53_03590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHR53_03600	COG0189	ligase activity
CHR53_03605	COG3540	Alkaline phosphatase
CHR53_03610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR53_03615	COG0805	protein transport
CHR53_03620	COG1704	LemA family
CHR53_03635	COG2972	Histidine kinase
CHR53_03645	COG1653	transport
CHR53_03650	COG1175	transmembrane transport
CHR53_03655	COG0395	ABC-type sugar transport system, permease component
CHR53_03670	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_03675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR53_03680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR53_03685	COG1653	transport
CHR53_03695	COG0395	ABC-type sugar transport system, permease component
CHR53_03700	COG3250	beta-galactosidase activity
CHR53_03705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CHR53_03710	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CHR53_03715	COG2017	converts alpha-aldose to the beta-anomer
CHR53_03720	COG1609	Transcriptional regulator
CHR53_03725	COG0833	amino acid
CHR53_03730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR53_03735	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR53_03740	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_03755	COG1725	Transcriptional regulator
CHR53_03760	COG1131	(ABC) transporter
CHR53_03770	COG1595	DNA-templated transcription, initiation
CHR53_03775	COG0586	Pfam SNARE associated Golgi protein
CHR53_03785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHR53_03790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHR53_03795	COG1136	(ABC) transporter
CHR53_03800	COG1136	(ABC) transporter
CHR53_03800	COG0577	efflux transmembrane transporter activity
CHR53_03805	COG0745	RESPONSE REGULATOR receiver
CHR53_03810	COG5002	protein histidine kinase activity
CHR53_03830	COG1473	amidohydrolase
CHR53_03865	COG1473	amidohydrolase
CHR53_03885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR53_03890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHR53_03900	COG2244	polysaccharide biosynthetic process
CHR53_03905	COG0297	glycogen (starch) synthase activity
CHR53_03905	COG0438	transferase activity, transferring glycosyl groups
CHR53_03910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHR53_03915	COG3307	-O-antigen
CHR53_03920	COG3206	protein involved in exopolysaccharide biosynthesis
CHR53_03925	COG1215	transferase activity, transferring glycosyl groups
CHR53_03930	COG0438	transferase activity, transferring glycosyl groups
CHR53_03940	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_03950	COG1854	S-ribosylhomocysteine lyase activity
CHR53_03960	COG3858	chitin binding
CHR53_03960	COG1388	LysM domain
CHR53_03975	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR53_03980	COG3842	ATPase activity
CHR53_03985	COG4149	molybdate abc transporter
CHR53_03990	COG0165	Argininosuccinate lyase
CHR53_03995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHR53_04010	COG0746	molybdenum cofactor guanylyltransferase activity
CHR53_04015	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_04025	COG2076	Multidrug Resistance protein
CHR53_04030	COG2076	Multidrug Resistance protein
CHR53_04035	COG1309	transcriptional regulator
CHR53_04040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR53_04055	COG0697	spore germination
CHR53_04060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR53_04080	COG1595	DNA-templated transcription, initiation
CHR53_04085	COG0590	tRNA wobble adenosine to inosine editing
CHR53_04090	COG1131	(ABC) transporter
CHR53_04105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_04110	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_04120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR53_04125	COG1193	negative regulation of DNA recombination
CHR53_04145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CHR53_04160	COG3541	Predicted nucleotidyltransferase
CHR53_04180	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHR53_04200	COG0438	transferase activity, transferring glycosyl groups
CHR53_04205	COG0671	phosphoesterase, PA-phosphatase related
CHR53_04240	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CHR53_04245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHR53_04250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR53_04255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR53_04260	COG1120	ATPase activity
CHR53_04270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR53_04290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHR53_04300	COG2860	membrane
CHR53_04310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHR53_04315	COG2323	membrane
CHR53_04375	COG0456	acetyltransferase
CHR53_04380	COG3708	Transcriptional regulator
CHR53_04380	COG2207	Transcriptional regulator
CHR53_04390	COG1902	pentaerythritol trinitrate reductase activity
CHR53_04400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHR53_04410	COG1607	acyl-coa hydrolase
CHR53_04415	COG0322	excinuclease ABC activity
CHR53_04470	COG0531	amino acid
CHR53_04490	COG2367	Beta-lactamase
CHR53_04510	COG0561	phosphatase activity
CHR53_04520	COG0431	NADPH-dependent FMN reductase
CHR53_04530	COG0400	carboxylic ester hydrolase activity
CHR53_04535	COG1764	response to oxidative stress
CHR53_04540	COG0655	NAD(P)H dehydrogenase (quinone) activity
CHR53_04565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CHR53_04575	COG0346	lactoylglutathione lyase activity
CHR53_04590	COG0776	regulation of translation
CHR53_04600	COG1657	PFAM Prenyltransferase squalene oxidase
CHR53_04630	COG1802	Transcriptional regulator
CHR53_04635	COG0579	oxidoreductase
CHR53_04660	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CHR53_04675	COG1113	amino acid transport
CHR53_04680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR53_04685	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_04690	COG0583	DNA-binding transcription factor activity
CHR53_04695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR53_04700	COG2340	Cysteine-rich secretory protein family
CHR53_04705	COG1017	nitric oxide dioxygenase activity
CHR53_04705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CHR53_04710	COG0640	Transcriptional regulator
CHR53_04715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CHR53_04720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHR53_04725	COG0039	L-malate dehydrogenase activity
CHR53_04755	COG2807	transmembrane transport
CHR53_04760	COG1473	amidohydrolase
CHR53_04780	COG0196	riboflavin kinase activity
CHR53_04790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_04795	COG1113	amino acid transport
CHR53_04825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR53_04840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR53_04860	COG0693	protein deglycase activity
CHR53_04875	COG0194	GDP metabolic process
CHR53_04880	COG1876	peptidase activity
CHR53_04885	COG0534	Mate efflux family protein
CHR53_04890	COG2132	Multicopper oxidase
CHR53_04895	COG0697	spore germination
CHR53_04915	COG4682	membrane
CHR53_04920	COG0069	glutamate synthase activity
CHR53_04925	COG1289	transmembrane transporter activity
CHR53_04930	COG1473	amidohydrolase
CHR53_04935	COG1473	amidohydrolase
CHR53_04940	COG2258	MOSC domain
CHR53_04965	COG0277	FAD linked oxidase domain protein
CHR53_04970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR53_04970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR53_04990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR53_05005	COG1011	Hydrolase
CHR53_05010	COG1073	alpha beta
CHR53_05015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CHR53_05020	COG1131	(ABC) transporter
CHR53_05035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_05050	COG0745	RESPONSE REGULATOR receiver
CHR53_05055	COG5002	protein histidine kinase activity
CHR53_05070	COG0772	Belongs to the SEDS family
CHR53_05080	COG1279	arginine transmembrane transporter activity
CHR53_05085	COG0582	viral genome integration into host DNA
CHR53_05100	COG1006	Multisubunit Na H antiporter MnhC subunit
CHR53_05105	COG0651	ATP synthesis coupled electron transport
CHR53_05110	COG1863	multisubunit Na H antiporter MnhE subunit
CHR53_05115	COG2212	antiporter activity
CHR53_05130	COG1051	belongs to the nudix hydrolase family
CHR53_05135	COG2814	Major facilitator Superfamily
CHR53_05140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR53_05155	COG2832	Protein of unknown function (DUF454)
CHR53_05160	COG0745	RESPONSE REGULATOR receiver
CHR53_05165	COG3850	Histidine kinase
CHR53_05165	COG5002	protein histidine kinase activity
CHR53_05190	COG3852	Histidine kinase
CHR53_05200	COG1595	DNA-templated transcription, initiation
CHR53_05230	COG0681	Belongs to the peptidase S26 family
CHR53_05235	COG2304	oxidoreductase activity
CHR53_05240	COG3340	Belongs to the peptidase S51 family
CHR53_05250	COG2808	Putative FMN-binding domain
CHR53_05255	COG0456	acetyltransferase
CHR53_05260	COG1846	Transcriptional regulator
CHR53_05290	COG1686	Belongs to the peptidase S11 family
CHR53_05295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CHR53_05300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CHR53_05305	COG1620	l-lactate permease
CHR53_05310	COG2186	Transcriptional regulator
CHR53_05315	COG0247	lactate metabolic process
CHR53_05320	COG1139	Iron-sulfur cluster binding protein
CHR53_05325	COG1556	Lactate utilization protein
CHR53_05340	COG1595	DNA-templated transcription, initiation
CHR53_05365	COG1122	ATPase activity
CHR53_05370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHR53_05375	COG0477	Major facilitator Superfamily
CHR53_05410	COG0745	RESPONSE REGULATOR receiver
CHR53_05415	COG5002	protein histidine kinase activity
CHR53_05415	COG5000	phosphorelay sensor kinase activity
CHR53_05445	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CHR53_05450	COG2329	Antibiotic biosynthesis monooxygenase
CHR53_05475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CHR53_05485	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR53_05490	COG3842	ATPase activity
CHR53_05500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_05505	COG1309	transcriptional regulator
CHR53_05525	COG4708	membrane
CHR53_05530	COG1609	Transcriptional regulator
CHR53_05540	COG1621	beta-fructofuranosidase activity
CHR53_05565	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR53_05575	COG1357	PFAM Pentapeptide repeats (8 copies)
CHR53_05580	COG2271	Major facilitator Superfamily
CHR53_05585	COG2076	Multidrug Resistance protein
CHR53_05590	COG2076	Multidrug Resistance protein
CHR53_05595	COG2346	COG2346, Truncated hemoglobins
CHR53_05610	COG2182	Extracellular solute-binding protein
CHR53_05615	COG1175	transmembrane transport
CHR53_05620	COG3833	ABC-type maltose transport systems, permease component
CHR53_05625	COG1609	Transcriptional regulator
CHR53_05630	COG0366	Alpha amylase catalytic
CHR53_05635	COG0534	Mate efflux family protein
CHR53_05645	COG1612	heme a metabolic process
CHR53_05660	COG0385	Bile acid
CHR53_05665	COG2233	PERMEase
CHR53_05670	COG3832	glyoxalase III activity
CHR53_05690	COG0166	Belongs to the GPI family
CHR53_05695	COG3189	MarR family transcriptional regulator
CHR53_05700	COG1272	protein, Hemolysin III
CHR53_05710	COG0697	spore germination
CHR53_05715	COG5434	Belongs to the glycosyl hydrolase 28 family
CHR53_05725	COG0456	acetyltransferase
CHR53_05730	COG0066	3-isopropylmalate dehydratase activity
CHR53_05735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHR53_05740	COG0473	3-isopropylmalate dehydrogenase activity
CHR53_05745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR53_05750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHR53_05755	COG0440	acetolactate synthase activity
CHR53_05760	COG0028	Belongs to the TPP enzyme family
CHR53_05765	COG0129	dihydroxy-acid dehydratase activity
CHR53_05780	COG0765	amino acid transport
CHR53_05805	COG1690	Belongs to the RtcB family
CHR53_05810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_05820	COG2814	Major facilitator Superfamily
CHR53_05830	COG0183	Belongs to the thiolase family
CHR53_05840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR53_05850	COG0514	ATP-dependent DNA helicase (RecQ)
CHR53_05855	COG3858	chitin binding
CHR53_05855	COG1388	LysM domain
CHR53_05860	COG1131	(ABC) transporter
CHR53_05870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHR53_05875	COG2814	Major facilitator Superfamily
CHR53_05880	COG2966	Psort location CytoplasmicMembrane, score
CHR53_05885	COG3610	response to peptide
CHR53_05890	COG4990	cell redox homeostasis
CHR53_05900	COG5002	protein histidine kinase activity
CHR53_05905	COG2199	diguanylate cyclase activity
CHR53_05905	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CHR53_05910	COG3344	reverse transcriptase
CHR53_05930	COG0243	molybdopterin cofactor binding
CHR53_05965	COG2197	response regulator
CHR53_05975	COG4585	Histidine kinase
CHR53_05985	COG0673	inositol 2-dehydrogenase activity
CHR53_05990	COG1114	Component of the transport system for branched-chain amino acids
CHR53_05995	COG0348	domain, Protein
CHR53_06005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR53_06030	COG0154	amidase activity
CHR53_06035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR53_06035	COG0723	plastoquinol--plastocyanin reductase activity
CHR53_06045	COG2340	Cysteine-rich secretory protein family
CHR53_06060	COG4758	membrane
CHR53_06070	COG2197	response regulator
CHR53_06075	COG2822	iron ion transport
CHR53_06080	COG2837	iron assimilation
CHR53_06085	COG0672	)-iron permease
CHR53_06090	COG2244	polysaccharide biosynthetic process
CHR53_06100	COG0670	Belongs to the BI1 family
CHR53_06110	COG2309	aminopeptidase activity
CHR53_06125	COG2986	histidine ammonia-lyase
CHR53_06140	COG1522	sequence-specific DNA binding
CHR53_06140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR53_06150	COG1396	sequence-specific DNA binding
CHR53_06155	COG0024	Methionine aminopeptidase
CHR53_06160	COG4840	Belongs to the UPF0435 family
CHR53_06170	COG1295	ribonuclease BN
CHR53_06175	COG2217	Heavy metal translocating P-type atpase
CHR53_06180	COG0477	Major facilitator Superfamily
CHR53_06185	COG0387	Pfam Sodium calcium exchanger
CHR53_06220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR53_06230	COG1174	glycine betaine transport
CHR53_06250	COG1278	Cold shock
CHR53_06255	COG4807	Protein conserved in bacteria
CHR53_06260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_06265	COG3275	phosphorelay sensor kinase activity
CHR53_06270	COG3279	Response regulator of the LytR AlgR family
CHR53_06275	COG3162	membrane
CHR53_06280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_06290	COG0517	IMP dehydrogenase activity
CHR53_06290	COG4175	Glycine betaine
CHR53_06310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR53_06325	COG2234	aminopeptidase activity
CHR53_06335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHR53_06345	COG1473	amidohydrolase
CHR53_06350	COG2234	aminopeptidase activity
CHR53_06355	COG2814	Major facilitator Superfamily
CHR53_06370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR53_06380	COG1113	amino acid transport
CHR53_06385	COG0701	Predicted permease
CHR53_06390	COG3689	TIGRFAM TIGR03943 family protein
CHR53_06400	COG1473	amidohydrolase
CHR53_06405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHR53_06410	COG3002	Belongs to the UPF0753 family
CHR53_06415	COG5609	conserved protein (DUF2294)
CHR53_06420	COG0288	reversible hydration of carbon dioxide
CHR53_06425	COG4191	Histidine kinase
CHR53_06430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR53_06435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR53_06470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHR53_06470	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHR53_06475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHR53_06480	COG0010	Belongs to the arginase family
CHR53_06485	COG0673	inositol 2-dehydrogenase activity
CHR53_06490	COG3104	oligopeptide transport
CHR53_06500	COG0789	Transcriptional regulator
CHR53_06505	COG0444	Belongs to the ABC transporter superfamily
CHR53_06510	COG4608	Belongs to the ABC transporter superfamily
CHR53_06515	COG0747	negative chemotaxis
CHR53_06530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHR53_06535	COG0710	3-dehydroquinate dehydratase activity
CHR53_06545	COG0737	Belongs to the 5'-nucleotidase family
CHR53_06545	COG4085	toxin activity
CHR53_06545	COG1525	nuclease
CHR53_06550	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHR53_06555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHR53_06560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CHR53_06565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR53_06570	COG0505	Belongs to the CarA family
CHR53_06575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHR53_06580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR53_06585	COG0137	argininosuccinate synthase activity
CHR53_06590	COG0165	Argininosuccinate lyase
CHR53_06595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR53_06595	COG3153	acetyltransferase
CHR53_06600	COG0456	acetyltransferase
CHR53_06610	COG0460	homoserine dehydrogenase
CHR53_06630	COG2137	regulation of response to DNA damage stimulus
CHR53_06655	COG1988	membrane-bound metal-dependent
CHR53_06660	COG1194	a g-specific adenine glycosylase
CHR53_06670	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_06690	COG1132	(ABC) transporter
CHR53_06695	COG4129	membrane
CHR53_06700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHR53_06705	COG4555	ABC transporter
CHR53_06725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CHR53_06730	COG0735	belongs to the Fur family
CHR53_06875	COG1742	UPF0060 membrane protein
CHR53_06885	COG1683	Conserved Protein
CHR53_06890	COG2211	Major facilitator Superfamily
CHR53_06915	COG3382	B3 4 domain protein
CHR53_06920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHR53_06930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CHR53_06935	COG0778	Nitroreductase
CHR53_06940	COG2766	serine protein kinase
CHR53_06945	COG2718	Belongs to the UPF0229 family
CHR53_07030	COG3655	Transcriptional regulator
CHR53_07070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR53_07070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR53_07115	COG1702	phosphate starvation-inducible protein PhoH
CHR53_07140	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHR53_07145	COG3584	3D domain protein
CHR53_07185	COG4474	Belongs to the UPF0398 family
CHR53_07325	COG1652	LysM domain
CHR53_07340	COG3628	GPW Gp25 family protein
CHR53_07345	COG3299	homolog of phage Mu protein gp47
CHR53_07375	COG3409	Peptidoglycan-binding domain 1 protein
CHR53_07405	COG0739	heme binding
CHR53_07420	COG2340	Cysteine-rich secretory protein family
CHR53_07425	COG5002	protein histidine kinase activity
CHR53_07435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHR53_07440	COG0363	glucosamine-6-phosphate deaminase activity
CHR53_07455	COG1940	carbohydrate kinase activity
CHR53_07460	COG1904	glucuronate isomerase
CHR53_07465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHR53_07475	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_07480	COG1606	tRNA processing
CHR53_07485	COG1070	Carbohydrate kinase
CHR53_07490	COG1691	(AIR) carboxylase
CHR53_07495	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CHR53_07530	COG2409	Drug exporters of the RND superfamily
CHR53_07535	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHR53_07540	COG0306	phosphate transporter
CHR53_07545	COG1392	Phosphate transport regulator
CHR53_07550	COG2261	transglycosylase associated protein
CHR53_07555	COG0564	pseudouridine synthase activity
CHR53_07565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR53_07575	COG2866	Carboxypeptidase
CHR53_07580	COG2719	SpoVR family
CHR53_07590	COG3384	dioxygenase
CHR53_07595	COG2259	Doxx family
CHR53_07605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHR53_07615	COG0686	Belongs to the AlaDH PNT family
CHR53_07620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CHR53_07620	COG2508	Transcriptional regulator
CHR53_07625	COG1113	amino acid transport
CHR53_07630	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CHR53_07640	COG2733	membrane
CHR53_07650	COG4841	protein insertion into membrane
CHR53_07670	COG1253	flavin adenine dinucleotide binding
CHR53_07675	COG0789	Transcriptional regulator
CHR53_07680	COG1253	flavin adenine dinucleotide binding
CHR53_07685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_07690	COG3859	Proton-coupled thiamine transporter YuaJ
CHR53_07715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR53_07730	COG0393	Putative heavy-metal-binding
CHR53_07735	COG1132	(ABC) transporter
CHR53_07740	COG1132	(ABC) transporter
CHR53_07745	COG0114	fumarate hydratase activity
CHR53_07760	COG3842	ATPase activity
CHR53_07765	COG2508	Transcriptional regulator
CHR53_07785	COG0189	ligase activity
CHR53_07790	COG0189	ligase activity
CHR53_07800	COG3679	Belongs to the UPF0342 family
CHR53_07805	COG0561	phosphatase activity
CHR53_07810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHR53_07820	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_07825	COG1024	Enoyl-CoA hydratase
CHR53_07835	COG4152	abc transporter atp-binding protein
CHR53_07840	COG1668	transmembrane transport
CHR53_07845	COG0420	3'-5' exonuclease activity
CHR53_07850	COG4717	serine-type aminopeptidase activity
CHR53_07855	COG3481	metal-dependent phosphohydrolase, HD sub domain
CHR53_07865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR53_07885	COG1846	Transcriptional regulator
CHR53_07900	COG0537	adenosine 5'-monophosphoramidase activity
CHR53_07905	COG1131	(ABC) transporter
CHR53_07910	COG4473	ABC transporter
CHR53_07920	COG3069	C4-dicarboxylate transmembrane transporter activity
CHR53_07925	COG2329	Antibiotic biosynthesis monooxygenase
CHR53_07930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CHR53_07945	COG1511	domain protein
CHR53_07950	COG1234	tRNA 3'-trailer cleavage
CHR53_07955	COG0095	Lipoate-protein ligase
CHR53_07960	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_07965	COG1024	Enoyl-CoA hydratase
CHR53_07970	COG0501	Belongs to the peptidase M48B family
CHR53_07980	COG4903	ComK protein
CHR53_07990	COG1316	TRANSCRIPTIONal
CHR53_07995	COG0398	Pfam SNARE associated Golgi protein
CHR53_08005	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CHR53_08045	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR53_08070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHR53_08080	COG0366	Alpha amylase catalytic
CHR53_08080	COG1874	Beta-galactosidase
CHR53_08085	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_08090	COG1666	GTP binding
CHR53_08095	COG2996	Protein conserved in bacteria
CHR53_08105	COG1307	EDD domain protein, DegV family
CHR53_08110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_08125	COG0561	phosphatase activity
CHR53_08130	COG2151	metal-sulfur cluster biosynthetic enzyme
CHR53_08145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR53_08150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CHR53_08155	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CHR53_08160	COG0303	'Molybdopterin
CHR53_08165	COG1763	Mo-molybdopterin cofactor biosynthetic process
CHR53_08175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR53_08185	COG0542	response to heat
CHR53_08195	COG2267	carboxylic ester hydrolase activity
CHR53_08205	COG1744	ABC transporter substrate-binding protein PnrA-like
CHR53_08220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR53_08225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR53_08230	COG5504	Zn-dependent protease
CHR53_08235	COG0444	Belongs to the ABC transporter superfamily
CHR53_08240	COG4608	Belongs to the ABC transporter superfamily
CHR53_08245	COG0747	negative chemotaxis
CHR53_08250	COG0601	transmembrane transport
CHR53_08255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR53_08265	COG0180	Tryptophanyl-tRNA synthetase
CHR53_08270	COG4166	transmembrane transport
CHR53_08275	COG0601	transmembrane transport
CHR53_08280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR53_08285	COG0444	Belongs to the ABC transporter superfamily
CHR53_08290	COG4608	Belongs to the ABC transporter superfamily
CHR53_08300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR53_08310	COG1393	Belongs to the ArsC family
CHR53_08315	COG4862	establishment of competence for transformation
CHR53_08320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR53_08330	COG1164	Oligoendopeptidase f
CHR53_08350	COG2346	COG2346, Truncated hemoglobins
CHR53_08355	COG4116	CYTH
CHR53_08365	COG2357	RelA SpoT domain protein
CHR53_08370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHR53_08375	COG0564	pseudouridine synthase activity
CHR53_08380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CHR53_08385	COG0475	glutathione-regulated potassium exporter activity
CHR53_08385	COG0569	domain protein
CHR53_08390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CHR53_08420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR53_08440	COG0210	DNA helicase
CHR53_08445	COG2153	protein acetylation
CHR53_08450	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CHR53_08455	COG2382	esterase
CHR53_08485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CHR53_08490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR53_08495	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR53_08500	COG4989	oxidoreductase activity
CHR53_08520	COG3239	Fatty acid desaturase
CHR53_08525	COG4585	Histidine kinase
CHR53_08530	COG2197	response regulator
CHR53_08535	COG2267	carboxylic ester hydrolase activity
CHR53_08545	COG2364	Membrane
CHR53_08560	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR53_08565	COG0697	spore germination
CHR53_08590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHR53_08595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CHR53_08600	COG1191	sigma factor activity
CHR53_08630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHR53_08635	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHR53_08640	COG5002	protein histidine kinase activity
CHR53_08645	COG0436	Aminotransferase
CHR53_08660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR53_08665	COG0644	oxidoreductase
CHR53_08680	COG2223	nitrite transmembrane transporter activity
CHR53_08685	COG3852	Histidine kinase
CHR53_08690	COG1846	Transcriptional regulator
CHR53_08700	COG0542	response to heat
CHR53_08705	COG3949	Membrane
CHR53_08720	COG4873	Protein conserved in bacteria
CHR53_08730	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CHR53_08735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHR53_08740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR53_08745	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CHR53_08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHR53_08760	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_08770	COG2084	Dehydrogenase
CHR53_08780	COG0436	Aminotransferase
CHR53_08790	COG1408	metallophosphoesterase
CHR53_08795	COG4990	cell redox homeostasis
CHR53_08800	COG2200	EAL domain
CHR53_08810	COG4703	Protein of unknown function (DUF1797)
CHR53_08815	COG0517	IMP dehydrogenase activity
CHR53_08820	COG0477	Major facilitator Superfamily
CHR53_08825	COG0583	DNA-binding transcription factor activity
CHR53_08830	COG2171	N-acyltransferase activity
CHR53_08835	COG1473	amidohydrolase
CHR53_08840	COG0450	alkyl hydroperoxide reductase
CHR53_08845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_08855	COG0569	domain protein
CHR53_08865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHR53_08875	COG0561	phosphatase activity
CHR53_08880	COG0242	peptide deformylase activity
CHR53_08895	COG0022	dehydrogenase e1 component
CHR53_08930	COG1982	Orn Lys Arg decarboxylase major
CHR53_08940	COG4476	Belongs to the UPF0223 family
CHR53_08945	COG4493	Belongs to the UPF0637 family
CHR53_08955	COG0483	inositol monophosphate 1-phosphatase activity
CHR53_08985	COG4896	Protein conserved in bacteria
CHR53_09000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CHR53_09005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CHR53_09015	COG0772	Belongs to the SEDS family
CHR53_09020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CHR53_09025	COG1612	heme a metabolic process
CHR53_09030	COG0109	protoheme IX farnesyltransferase activity
CHR53_09055	COG3336	cytochrome c oxidase
CHR53_09070	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CHR53_09075	COG2340	Cysteine-rich secretory protein family
CHR53_09095	COG3679	Belongs to the UPF0342 family
CHR53_09100	COG4471	UPF0298 protein
CHR53_09105	COG0742	ribosomal rna small subunit methyltransferase
CHR53_09110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHR53_09115	COG3314	Sporulation integral membrane protein YlbJ
CHR53_09120	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHR53_09125	COG3480	Lon protease (S16) C-terminal proteolytic domain
CHR53_09130	COG1323	Belongs to the UPF0348 family
CHR53_09135	COG1399	metal-binding, possibly nucleic acid-binding protein
CHR53_09140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CHR53_09145	COG1024	Enoyl-CoA hydratase
CHR53_09155	COG0454	-acetyltransferase
CHR53_09160	COG0439	Biotin carboxylase
CHR53_09165	COG0511	ligase activity, forming carbon-carbon bonds
CHR53_09170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHR53_09175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHR53_09185	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CHR53_09190	COG2001	Belongs to the MraZ family
CHR53_09210	COG0768	penicillin binding
CHR53_09215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHR53_09225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHR53_09230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHR53_09235	COG0772	Belongs to the SEDS family
CHR53_09240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR53_09245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHR53_09250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CHR53_09255	COG3879	Bacterial protein of unknown function (DUF881)
CHR53_09260	COG3879	Bacterial protein of unknown function (DUF881)
CHR53_09265	COG3856	small basic protein
CHR53_09270	COG0849	cell division
CHR53_09275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHR53_09285	COG1191	sigma factor activity
CHR53_09290	COG1191	sigma factor activity
CHR53_09295	COG1873	PFAM PRC-barrel domain
CHR53_09305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHR53_09310	COG1799	cell septum assembly
CHR53_09315	COG0762	integral membrane protein
CHR53_09320	COG2302	S4 RNA-binding domain
CHR53_09325	COG3599	regulation of cell shape
CHR53_09345	COG0564	pseudouridine synthase activity
CHR53_09350	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CHR53_09365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHR53_09385	COG0167	dihydroorotate dehydrogenase activity
CHR53_09390	COG0284	orotidine-5'-phosphate decarboxylase activity
CHR53_09395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHR53_09405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CHR53_09410	COG1561	YicC-like family, N-terminal region
CHR53_09420	COG0194	GDP metabolic process
CHR53_09425	COG1758	RNA polymerase activity
CHR53_09430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHR53_09435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHR53_09445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHR53_09450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHR53_09450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHR53_09455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CHR53_09460	COG0631	protein serine/threonine phosphatase activity
CHR53_09465	COG2815	serine threonine protein kinase
CHR53_09465	COG0515	serine threonine protein kinase
CHR53_09470	COG1162	GTPase activity
CHR53_09475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHR53_09480	COG1564	THIamine pyrophosphokinase
CHR53_09490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHR53_09495	COG1302	Protein conserved in bacteria
CHR53_09500	COG1461	Dihydroxyacetone kinase
CHR53_09505	COG1760	l-serine dehydratase
CHR53_09510	COG1760	l-serine dehydratase
CHR53_09515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHR53_09520	COG1349	DNA-binding transcription factor activity
CHR53_09525	COG0416	fatty acid biosynthetic process
CHR53_09530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHR53_09535	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_09540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR53_09545	COG0571	ribonuclease III activity
CHR53_09550	COG1196	nuclear chromosome segregation
CHR53_09555	COG0552	protein localization to endoplasmic reticulum
CHR53_09560	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CHR53_09565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHR53_09575	COG1837	Belongs to the UPF0109 family
CHR53_09585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHR53_09590	COG0336	Belongs to the RNA methyltransferase TrmD family
CHR53_09595	COG0335	large ribosomal subunit rRNA binding
CHR53_09605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CHR53_09615	COG0045	succinate-CoA ligase (ADP-forming) activity
CHR53_09620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHR53_09625	COG0758	DNA mediated transformation
CHR53_09635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHR53_09640	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CHR53_09650	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CHR53_09655	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CHR53_09660	COG0052	Belongs to the universal ribosomal protein uS2 family
CHR53_09670	COG0528	UMP kinase activity
CHR53_09675	COG0233	cytoplasmic translational termination
CHR53_09685	COG4589	Belongs to the CDS family
CHR53_09690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CHR53_09695	COG0750	zinc metalloprotease
CHR53_09700	COG2176	DNA-directed DNA polymerase activity
CHR53_09705	COG0779	Required for maturation of 30S ribosomal subunits
CHR53_09710	COG0195	Participates in both transcription termination and antitermination
CHR53_09715	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CHR53_09720	COG1358	cellular component organization or biogenesis
CHR53_09730	COG1550	Protein conserved in bacteria
CHR53_09740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHR53_09745	COG0196	riboflavin kinase activity
CHR53_09750	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHR53_09755	COG1185	polyribonucleotide nucleotidyltransferase activity
CHR53_09760	COG0726	polysaccharide deacetylase
CHR53_09765	COG0612	Peptidase, M16
CHR53_09770	COG1873	PFAM PRC-barrel domain
CHR53_09775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR53_09780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHR53_09785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHR53_09790	COG0527	aspartate kinase activity
CHR53_09795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR53_09800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHR53_09805	COG0740	serine-type endopeptidase activity
CHR53_09815	COG4980	gas vesicle protein
CHR53_09815	COG1674	ftsk spoiiie
CHR53_09820	COG2188	Transcriptional regulator
CHR53_09845	COG0612	Peptidase, M16
CHR53_09850	COG0612	Peptidase, M16
CHR53_09855	COG0300	oxidoreductase activity
CHR53_09870	COG1426	Protein conserved in bacteria
CHR53_09875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHR53_09880	COG1058	Belongs to the CinA family
CHR53_09880	COG1546	Belongs to the CinA family
CHR53_09885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHR53_09895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHR53_09905	COG1418	mRNA catabolic process
CHR53_09910	COG1692	metallophosphoesterase
CHR53_09915	COG2359	stage V sporulation protein S
CHR53_09920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CHR53_09920	COG0674	pyruvate-flavodoxin oxidoreductase activity
CHR53_09925	COG1013	pyruvate-flavodoxin oxidoreductase activity
CHR53_09930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHR53_09935	COG4550	Control of competence regulator ComK, YlbF/YmcA
CHR53_09950	COG0583	DNA-binding transcription factor activity
CHR53_09965	COG0196	riboflavin kinase activity
CHR53_09970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR53_09975	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_09995	COG4978	Transcriptional regulator
CHR53_09995	COG0789	Transcriptional regulator
CHR53_10000	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_10005	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR53_10035	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR53_10065	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CHR53_10070	COG1234	tRNA 3'-trailer cleavage
CHR53_10080	COG2271	Major facilitator Superfamily
CHR53_10085	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_10095	COG0531	amino acid
CHR53_10100	COG1234	tRNA 3'-trailer cleavage
CHR53_10105	COG1940	carbohydrate kinase activity
CHR53_10110	COG2059	Chromate
CHR53_10115	COG2059	Chromate
CHR53_10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_10125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR53_10130	COG3829	transcription factor binding
CHR53_10135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR53_10145	COG1228	amidohydrolase
CHR53_10150	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHR53_10155	COG2056	Na+-H+ antiporter family
CHR53_10160	COG2986	histidine ammonia-lyase
CHR53_10165	COG1119	ATPase activity
CHR53_10170	COG1280	lysine exporter protein (LysE YggA)
CHR53_10175	COG2368	4-hydroxyphenylacetate
CHR53_10210	COG2814	Major facilitator Superfamily
CHR53_10215	COG0789	Transcriptional regulator
CHR53_10240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_10250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR53_10265	COG1937	Protein conserved in bacteria
CHR53_10270	COG2210	Belongs to the sulfur carrier protein TusA family
CHR53_10280	COG0425	Belongs to the sulfur carrier protein TusA family
CHR53_10280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_10285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_10285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_10290	COG0425	Belongs to the sulfur carrier protein TusA family
CHR53_10310	COG1388	LysM domain
CHR53_10315	COG5002	protein histidine kinase activity
CHR53_10320	COG0745	RESPONSE REGULATOR receiver
CHR53_10330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR53_10335	COG3871	stress protein (general stress protein 26)
CHR53_10340	COG2155	Conserved Protein
CHR53_10345	COG1404	Belongs to the peptidase S8 family
CHR53_10360	COG5522	Integral membrane protein (intg_mem_TP0381)
CHR53_10365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHR53_10370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHR53_10375	COG1077	Cell shape determining protein MreB Mrl
CHR53_10380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHR53_10385	COG1923	regulation of RNA biosynthetic process
CHR53_10390	COG0464	growth
CHR53_10395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHR53_10400	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CHR53_10405	COG0789	Transcriptional regulator
CHR53_10410	COG0174	glutamine synthetase
CHR53_10420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHR53_10425	COG1388	LysM domain
CHR53_10430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR53_10450	COG3763	UPF0154 protein
CHR53_10455	COG1132	(ABC) transporter
CHR53_10460	COG1132	(ABC) transporter
CHR53_10470	COG0785	Cytochrome C biogenesis protein
CHR53_10475	COG4846	Membrane protein involved in cytochrome C biogenesis
CHR53_10490	COG0322	excinuclease ABC activity
CHR53_10540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR53_10565	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CHR53_10575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR53_10585	COG1473	amidohydrolase
CHR53_10590	COG2205	protein histidine kinase activity
CHR53_10610	COG0475	glutathione-regulated potassium exporter activity
CHR53_10640	COG2814	Major facilitator Superfamily
CHR53_10655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_10660	COG4191	Histidine kinase
CHR53_10675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_10680	COG0656	L-ascorbic acid biosynthetic process
CHR53_10685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_10690	COG2814	Major facilitator Superfamily
CHR53_10700	COG1846	Transcriptional regulator
CHR53_10705	COG1027	Aspartate ammonia-lyase
CHR53_10715	COG2720	vancomycin resistance protein
CHR53_10725	COG1695	Transcriptional regulator
CHR53_10745	COG0659	secondary active sulfate transmembrane transporter activity
CHR53_10755	COG1278	Cold shock
CHR53_10765	COG0419	ATPase involved in DNA repair
CHR53_10775	COG0110	maltose O-acetyltransferase activity
CHR53_10785	COG1573	uracil-dna glycosylase
CHR53_10790	COG0406	alpha-ribazole phosphatase activity
CHR53_10810	COG1914	H( )-stimulated, divalent metal cation uptake system
CHR53_10815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHR53_10820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CHR53_10825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHR53_10835	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHR53_10845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR53_10850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR53_10855	COG2986	histidine ammonia-lyase
CHR53_10865	COG2207	Transcriptional regulator
CHR53_10870	COG2056	Na+-H+ antiporter family
CHR53_10875	COG1733	regulation of RNA biosynthetic process
CHR53_10885	COG2310	stress, protein
CHR53_10890	COG2362	D-Aminopeptidase
CHR53_10895	COG0601	transmembrane transport
CHR53_10900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR53_10905	COG0444	Belongs to the ABC transporter superfamily
CHR53_10910	COG4166	transmembrane transport
CHR53_10915	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHR53_10920	COG4948	Mandelate Racemase Muconate Lactonizing
CHR53_10925	COG0791	NLP P60 protein
CHR53_10930	COG4608	Belongs to the ABC transporter superfamily
CHR53_10940	COG1115	amino acid carrier protein
CHR53_10945	COG2409	Drug exporters of the RND superfamily
CHR53_10945	COG1033	growth of symbiont in host cell
CHR53_10950	COG1846	Transcriptional regulator
CHR53_10960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHR53_10980	COG1131	(ABC) transporter
CHR53_10985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CHR53_10995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR53_11000	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CHR53_11005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR53_11010	COG1696	Membrane protein involved in D-alanine export
CHR53_11015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CHR53_11025	COG1363	Peptidase, m42
CHR53_11035	COG0598	Magnesium transport protein CorA
CHR53_11040	COG0697	spore germination
CHR53_11060	COG0398	Pfam SNARE associated Golgi protein
CHR53_11070	COG0477	Major facilitator Superfamily
CHR53_11085	COG2080	2 iron, 2 sulfur cluster binding
CHR53_11115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CHR53_11120	COG0861	Integral membrane protein TerC family
CHR53_11125	COG5002	protein histidine kinase activity
CHR53_11130	COG0745	RESPONSE REGULATOR receiver
CHR53_11135	COG0671	phosphoesterase, PA-phosphatase related
CHR53_11140	COG1183	phosphatidylcholine synthase activity
CHR53_11145	COG1132	(ABC) transporter
CHR53_11150	COG0561	phosphatase activity
CHR53_11155	COG0753	catalase activity
CHR53_11165	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_11180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHR53_11180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CHR53_11185	COG0307	riboflavin synthase, alpha
CHR53_11190	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR53_11190	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR53_11195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHR53_11200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHR53_11205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHR53_11210	COG1120	ATPase activity
CHR53_11215	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CHR53_11225	COG1492	cobalamin metabolic process
CHR53_11230	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CHR53_11245	COG2096	Adenosyltransferase
CHR53_11260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR53_11270	COG1136	(ABC) transporter
CHR53_11275	COG0577	efflux transmembrane transporter activity
CHR53_11295	COG0697	spore germination
CHR53_11305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR53_11310	COG5002	protein histidine kinase activity
CHR53_11315	COG1247	-acetyltransferase
CHR53_11340	COG2818	Glycosylase
CHR53_11350	COG2357	RelA SpoT domain protein
CHR53_11360	COG2270	Major facilitator Superfamily
CHR53_11370	COG1329	Transcriptional regulator
CHR53_11390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR53_11395	COG1228	amidohydrolase
CHR53_11425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHR53_11430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHR53_11435	COG2234	aminopeptidase activity
CHR53_11445	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CHR53_11450	COG0351	phosphomethylpyrimidine kinase
CHR53_11465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_11470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CHR53_11475	COG1116	anion transmembrane transporter activity
CHR53_11480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR53_11485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR53_11490	COG1301	dicarboxylic acid transport
CHR53_11500	COG3290	protein histidine kinase activity
CHR53_11530	COG0534	Mate efflux family protein
CHR53_11560	COG2112	serine threonine protein kinase
CHR53_11565	COG0438	transferase activity, transferring glycosyl groups
CHR53_11570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR53_11595	COG0577	efflux transmembrane transporter activity
CHR53_11600	COG1136	(ABC) transporter
CHR53_11605	COG2205	protein histidine kinase activity
CHR53_11610	COG0745	RESPONSE REGULATOR receiver
CHR53_11615	COG1966	Carbon starvation protein
CHR53_11655	COG1164	Oligoendopeptidase f
CHR53_11675	COG0175	sulfate reduction
CHR53_11680	COG0306	phosphate transporter
CHR53_11685	COG2046	Belongs to the sulfate adenylyltransferase family
CHR53_11690	COG0529	Catalyzes the synthesis of activated sulfate
CHR53_11705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CHR53_11710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CHR53_11715	COG0402	S-adenosylhomocysteine deaminase activity
CHR53_11720	COG0412	Dienelactone hydrolase
CHR53_11725	COG2217	Heavy metal translocating P-type atpase
CHR53_11730	COG2936	dipeptidyl-peptidase activity
CHR53_11740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CHR53_11740	COG2105	PFAM AIG2 family protein
CHR53_11745	COG0484	heat shock protein binding
CHR53_11755	COG1404	Belongs to the peptidase S8 family
CHR53_11760	COG1183	phosphatidylcholine synthase activity
CHR53_11765	COG2066	Belongs to the glutaminase family
CHR53_11785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR53_11810	COG0697	spore germination
CHR53_11825	COG2267	carboxylic ester hydrolase activity
CHR53_11835	COG3858	chitin binding
CHR53_11840	COG1114	Component of the transport system for branched-chain amino acids
CHR53_11845	COG4895	conserved protein (DUF2196)
CHR53_11880	COG0791	NLP P60 protein
CHR53_11880	COG1388	LysM domain
CHR53_11910	COG0640	Transcriptional regulator
CHR53_11940	COG0745	RESPONSE REGULATOR receiver
CHR53_11945	COG2205	protein histidine kinase activity
CHR53_11950	COG2318	DinB family
CHR53_11955	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CHR53_11960	COG1335	isochorismatase
CHR53_11965	COG1522	sequence-specific DNA binding
CHR53_11970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHR53_11990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CHR53_12000	COG0154	amidase activity
CHR53_12015	COG1074	ATP-dependent DNA helicase activity
CHR53_12030	COG0745	RESPONSE REGULATOR receiver
CHR53_12065	COG1132	(ABC) transporter
CHR53_12070	COG1404	Belongs to the peptidase S8 family
CHR53_12135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR53_12150	COG0671	phosphoesterase, PA-phosphatase related
CHR53_12155	COG0745	RESPONSE REGULATOR receiver
CHR53_12160	COG5002	protein histidine kinase activity
CHR53_12160	COG3850	Histidine kinase
CHR53_12165	COG0586	Pfam SNARE associated Golgi protein
CHR53_12185	COG3773	Cell wall hydrolase
CHR53_12190	COG3848	Pyruvate phosphate dikinase
CHR53_12190	COG0574	Belongs to the PEP-utilizing enzyme family
CHR53_12205	COG0456	acetyltransferase
CHR53_12240	COG0791	NLP P60 protein
CHR53_12250	COG0861	Integral membrane protein TerC family
CHR53_12255	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHR53_12260	COG1414	Transcriptional regulator
CHR53_12265	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_12275	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR53_12285	COG2721	sulfolactate sulfo-lyase activity
CHR53_12295	COG2721	sulfolactate sulfo-lyase activity
CHR53_12300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR53_12305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHR53_12310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CHR53_12315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR53_12320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR53_12330	COG0129	dihydroxy-acid dehydratase activity
CHR53_12335	COG1414	Transcriptional regulator
CHR53_12345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR53_12360	COG0346	lactoylglutathione lyase activity
CHR53_12375	COG1476	TRANSCRIPTIONal
CHR53_12390	COG0456	acetyltransferase
CHR53_12415	COG2234	aminopeptidase activity
CHR53_12420	COG2234	aminopeptidase activity
CHR53_12425	COG3706	GGDEF domain
CHR53_12435	COG4841	protein insertion into membrane
CHR53_12440	COG1215	transferase activity, transferring glycosyl groups
CHR53_12445	COG1283	sodium-dependent phosphate transmembrane transporter activity
CHR53_12460	COG0477	Major facilitator Superfamily
CHR53_12465	COG3842	ATPase activity
CHR53_12470	COG1178	ABC-type Fe3 transport system permease component
CHR53_12475	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR53_12485	COG4176	ABC-type proline glycine betaine transport system permease component
CHR53_12495	COG1999	signal sequence binding
CHR53_12500	COG1595	DNA-templated transcription, initiation
CHR53_12520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHR53_12530	COG0217	transcriptional regulatory protein
CHR53_12535	COG0697	spore germination
CHR53_12540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHR53_12555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHR53_12560	COG2135	peptidase activity
CHR53_12565	COG2188	Transcriptional regulator
CHR53_12570	COG0366	Alpha amylase catalytic
CHR53_12575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR53_12575	COG1263	PTS System
CHR53_12580	COG0861	Integral membrane protein TerC family
CHR53_12595	COG3011	Protein conserved in bacteria
CHR53_12605	COG2070	2-Nitropropane dioxygenase
CHR53_12620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR53_12625	COG0765	amino acid transport
CHR53_12655	COG1533	DNA photolyase activity
CHR53_12660	COG0425	Belongs to the sulfur carrier protein TusA family
CHR53_12660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_12665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_12665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_12670	COG0730	response to heat
CHR53_12675	COG2210	Belongs to the sulfur carrier protein TusA family
CHR53_12690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_12710	COG2814	Major facilitator Superfamily
CHR53_12715	COG0488	(ABC) transporter
CHR53_12735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR53_12750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR53_12790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHR53_12795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_12815	COG0464	growth
CHR53_12820	COG0824	Thioesterase
CHR53_12830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHR53_12835	COG3852	Histidine kinase
CHR53_12840	COG1832	CoA-binding protein
CHR53_12845	COG0187	DNA topoisomerase II activity
CHR53_12850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHR53_12870	COG1132	(ABC) transporter
CHR53_12875	COG0745	RESPONSE REGULATOR receiver
CHR53_12880	COG2205	protein histidine kinase activity
CHR53_12885	COG1136	(ABC) transporter
CHR53_12890	COG0577	efflux transmembrane transporter activity
CHR53_12895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR53_12900	COG2252	PERMEase
CHR53_12910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHR53_12910	COG3608	succinylglutamate desuccinylase aspartoacylase
CHR53_12915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CHR53_12925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHR53_12955	COG0163	prenyltransferase activity
CHR53_12965	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHR53_12980	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHR53_12990	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CHR53_12995	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CHR53_13000	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CHR53_13005	COG3665	Urea carboxylase-associated protein
CHR53_13010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_13015	COG0402	S-adenosylhomocysteine deaminase activity
CHR53_13020	COG4974	Belongs to the 'phage' integrase family
CHR53_13035	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR53_13045	COG0402	S-adenosylhomocysteine deaminase activity
CHR53_13050	COG0402	S-adenosylhomocysteine deaminase activity
CHR53_13070	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_13080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR53_13085	COG0697	spore germination
CHR53_13110	COG5577	PFAM Coat F domain
CHR53_13120	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_13160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CHR53_13170	COG1714	RDD family
CHR53_13185	COG0714	Associated with various cellular activities
CHR53_13205	COG1215	transferase activity, transferring glycosyl groups
CHR53_13220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR53_13235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_13245	COG1114	Component of the transport system for branched-chain amino acids
CHR53_13250	COG3829	transcription factor binding
CHR53_13255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR53_13260	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_13285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHR53_13290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHR53_13295	COG0655	NAD(P)H dehydrogenase (quinone) activity
CHR53_13300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHR53_13325	COG0493	'glutamate synthase
CHR53_13330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR53_13335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR53_13340	COG2056	Na+-H+ antiporter family
CHR53_13345	COG3328	transposase activity
CHR53_13350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR53_13355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR53_13360	COG2207	Transcriptional regulator
CHR53_13370	COG1116	anion transmembrane transporter activity
CHR53_13375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR53_13380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR53_13385	COG2204	response regulator
CHR53_13400	COG3258	Cytochrome c
CHR53_13405	COG0425	Belongs to the sulfur carrier protein TusA family
CHR53_13410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_13425	COG2814	Major facilitator Superfamily
CHR53_13440	COG2234	aminopeptidase activity
CHR53_13450	COG1164	Oligoendopeptidase f
CHR53_13455	COG0716	FMN binding
CHR53_13460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR53_13465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR53_13480	COG0737	Belongs to the 5'-nucleotidase family
CHR53_13480	COG1525	nuclease
CHR53_13480	COG4085	toxin activity
CHR53_13485	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_13495	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_13500	COG2720	vancomycin resistance protein
CHR53_13510	COG0506	proline dehydrogenase activity
CHR53_13520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHR53_13525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_13535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR53_13570	COG0312	modulator of DNA gyrase
CHR53_13575	COG0312	modulator of DNA gyrase
CHR53_13580	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CHR53_13580	COG0778	Nitroreductase
CHR53_13590	COG0028	Belongs to the TPP enzyme family
CHR53_13600	COG0512	Glutamine amidotransferase of anthranilate synthase
CHR53_13620	COG0596	Alpha beta hydrolase
CHR53_13625	COG1090	epimerase
CHR53_13680	COG0402	S-adenosylhomocysteine deaminase activity
CHR53_13685	COG2235	arginine
CHR53_13695	COG0765	amino acid transport
CHR53_13700	COG1126	abc transporter atp-binding protein
CHR53_13705	COG2235	arginine
CHR53_13720	COG2226	methyltransferase
CHR53_13730	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_13735	COG2610	gluconate transmembrane transporter activity
CHR53_13740	COG0583	DNA-binding transcription factor activity
CHR53_13745	COG2814	Major facilitator Superfamily
CHR53_13750	COG1566	PFAM secretion protein HlyD family protein
CHR53_13760	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_13770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHR53_13780	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_13790	COG3829	transcription factor binding
CHR53_13790	COG3290	protein histidine kinase activity
CHR53_13795	COG0405	Gamma-glutamyltransferase
CHR53_13825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CHR53_13830	COG1309	transcriptional regulator
CHR53_13835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHR53_13865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CHR53_13895	COG0004	ammonium transporteR
CHR53_13900	COG0367	asparagine synthase
CHR53_13910	COG0069	glutamate synthase activity
CHR53_13910	COG0070	glutamate synthase
CHR53_13910	COG0067	glutamate synthase
CHR53_13915	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_13920	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_13925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR53_13935	COG0022	dehydrogenase e1 component
CHR53_13940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR53_13955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHR53_13960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR53_13965	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_13985	COG2027	D-alanyl-D-alanine carboxypeptidase
CHR53_14005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CHR53_14010	COG3764	Sortase (surface protein transpeptidase)
CHR53_14025	COG2271	Major facilitator Superfamily
CHR53_14030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CHR53_14040	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_14045	COG0583	DNA-binding transcription factor activity
CHR53_14050	COG3852	Histidine kinase
CHR53_14075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_14080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHR53_14085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHR53_14090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHR53_14095	COG2318	DinB family
CHR53_14100	COG1733	regulation of RNA biosynthetic process
CHR53_14105	COG0778	Nitroreductase
CHR53_14140	COG1278	Cold shock
CHR53_14160	COG3973	AAA domain
CHR53_14175	COG0513	Belongs to the DEAD box helicase family
CHR53_14185	COG0247	lactate metabolic process
CHR53_14190	COG0277	FAD linked oxidase domain protein
CHR53_14215	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CHR53_14225	COG3620	sequence-specific DNA binding
CHR53_14230	COG0534	Mate efflux family protein
CHR53_14235	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CHR53_14245	COG0154	amidase activity
CHR53_14250	COG2271	Major facilitator Superfamily
CHR53_14260	COG0028	Belongs to the TPP enzyme family
CHR53_14265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR53_14270	COG1414	Transcriptional regulator
CHR53_14275	COG1301	dicarboxylic acid transport
CHR53_14280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR53_14300	COG1396	sequence-specific DNA binding
CHR53_14335	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR53_14345	COG0346	lactoylglutathione lyase activity
CHR53_14370	COG0666	response to abiotic stimulus
CHR53_14375	COG0590	tRNA wobble adenosine to inosine editing
CHR53_14380	COG2233	PERMEase
CHR53_14385	COG0583	DNA-binding transcription factor activity
CHR53_14400	COG2816	NAD+ diphosphatase activity
CHR53_14415	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_14430	COG0492	ferredoxin-NADP+ reductase activity
CHR53_14435	COG1959	2 iron, 2 sulfur cluster binding
CHR53_14460	COG5577	PFAM Coat F domain
CHR53_14465	COG1063	alcohol dehydrogenase
CHR53_14475	COG5577	PFAM Coat F domain
CHR53_14485	COG1335	isochorismatase
CHR53_14500	COG2890	protein-(glutamine-N5) methyltransferase activity
CHR53_14545	COG4319	ketosteroid isomerase
CHR53_14550	COG2391	methyltransferase activity
CHR53_14580	COG3243	poly(R)-hydroxyalkanoic acid synthase
CHR53_14590	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_14600	COG1278	Cold shock
CHR53_14615	COG1278	Cold shock
CHR53_14625	COG1278	Cold shock
CHR53_14635	COG0346	lactoylglutathione lyase activity
CHR53_14650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_14705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHR53_14720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHR53_14755	COG1595	DNA-templated transcription, initiation
CHR53_14770	COG1309	transcriptional regulator
CHR53_14845	COG0681	Belongs to the peptidase S26 family
CHR53_14860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR53_14890	COG1115	amino acid carrier protein
CHR53_14895	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CHR53_14930	COG1609	Transcriptional regulator
CHR53_14935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CHR53_14955	COG1733	regulation of RNA biosynthetic process
CHR53_14980	COG0778	Nitroreductase
CHR53_15060	COG0662	Cupin 2, conserved barrel domain protein
CHR53_15110	COG0672	)-iron permease
CHR53_15130	COG1254	Belongs to the acylphosphatase family
CHR53_15180	COG2318	DinB family
CHR53_15195	COG4974	Belongs to the 'phage' integrase family
CHR53_15215	COG1846	Transcriptional regulator
CHR53_15225	COG0776	regulation of translation
CHR53_15230	COG2318	DinB family
CHR53_15250	COG4974	Belongs to the 'phage' integrase family
CHR53_15265	COG4974	Belongs to the 'phage' integrase family
CHR53_15270	COG2226	methyltransferase
CHR53_15290	COG1278	Cold shock
CHR53_15310	COG0154	amidase activity
CHR53_15315	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_15320	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_15345	COG0477	Major facilitator Superfamily
CHR53_15350	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_15355	COG0686	Belongs to the AlaDH PNT family
CHR53_15355	COG0686	Belongs to the AlaDH PNT family
CHR53_15370	COG0247	lactate metabolic process
CHR53_15375	COG0277	FAD linked oxidase domain protein
CHR53_15380	COG2808	Putative FMN-binding domain
CHR53_15385	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_15390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR53_15400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR53_15405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_15415	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR53_15420	COG0410	ABC transporter
CHR53_15425	COG0411	ABC transporter
CHR53_15450	COG2814	Major facilitator Superfamily
CHR53_15515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CHR53_15545	COG0758	DNA mediated transformation
CHR53_15645	COG0346	lactoylglutathione lyase activity
CHR53_15675	COG4608	Belongs to the ABC transporter superfamily
CHR53_15690	COG0601	transmembrane transport
CHR53_15695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR53_15700	COG0747	negative chemotaxis
CHR53_15705	COG0473	3-isopropylmalate dehydrogenase activity
CHR53_15705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CHR53_15720	COG1595	DNA-templated transcription, initiation
CHR53_15750	COG1525	nuclease
CHR53_15760	COG0305	Participates in initiation and elongation during chromosome replication
CHR53_15770	COG2814	Major facilitator Superfamily
CHR53_15780	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHR53_15790	COG0523	cobalamin synthesis protein
CHR53_15795	COG3443	Belongs to the bacterial solute-binding protein 9 family
CHR53_15795	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHR53_15800	COG0701	Predicted permease
CHR53_15810	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_15815	COG1053	succinate dehydrogenase
CHR53_15820	COG0583	DNA-binding transcription factor activity
CHR53_15825	COG3180	Ammonia monooxygenase
CHR53_15830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR53_15835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR53_15855	COG0477	Major facilitator Superfamily
CHR53_15860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHR53_15865	COG2427	Protein of unknown function (DUF1641)
CHR53_15870	COG3383	formate dehydrogenase (NAD+) activity
CHR53_15890	COG2207	Transcriptional regulator
CHR53_15900	COG0488	(ABC) transporter
CHR53_15920	COG0400	carboxylic ester hydrolase activity
CHR53_15925	COG0346	lactoylglutathione lyase activity
CHR53_15930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR53_15935	COG0346	lactoylglutathione lyase activity
CHR53_15940	COG2259	Doxx family
CHR53_15945	COG1846	Transcriptional regulator
CHR53_15970	COG2851	Citrate transporter
CHR53_16000	COG2323	membrane
CHR53_16010	COG2814	Major facilitator Superfamily
CHR53_16015	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_16025	COG1960	acyl-CoA dehydrogenase activity
CHR53_16035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR53_16045	COG2030	dehydratase
CHR53_16050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_16050	COG1042	CoA-binding domain protein
CHR53_16050	COG0045	succinate-CoA ligase (ADP-forming) activity
CHR53_16060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR53_16080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CHR53_16090	COG1266	CAAX protease self-immunity
CHR53_16105	COG2353	YceI-like domain
CHR53_16125	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_16130	COG0583	DNA-binding transcription factor activity
CHR53_16150	COG1418	mRNA catabolic process
CHR53_16155	COG4129	membrane
CHR53_16175	COG1556	Lactate utilization protein
CHR53_16180	COG1139	Iron-sulfur cluster binding protein
CHR53_16190	COG0583	DNA-binding transcription factor activity
CHR53_16220	COG5566	PFAM Mor transcription activator
CHR53_16240	COG0154	amidase activity
CHR53_16245	COG1301	dicarboxylic acid transport
CHR53_16260	COG2186	Transcriptional regulator
CHR53_16270	COG5658	integral membrane protein
CHR53_16275	COG0640	Transcriptional regulator
CHR53_16285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR53_16300	COG0656	L-ascorbic acid biosynthetic process
CHR53_16305	COG2814	Major facilitator Superfamily
CHR53_16310	COG1733	regulation of RNA biosynthetic process
CHR53_16320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHR53_16325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHR53_16340	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CHR53_16345	COG0788	formyltetrahydrofolate deformylase activity
CHR53_16350	COG2323	membrane
CHR53_16375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR53_16380	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_16390	COG0410	ABC transporter
CHR53_16395	COG0411	ABC transporter
CHR53_16405	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR53_16420	COG2814	Major facilitator Superfamily
CHR53_16425	COG0602	queuosine metabolic process
CHR53_16430	COG0720	synthase
CHR53_16450	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CHR53_16460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHR53_16470	COG5609	conserved protein (DUF2294)
CHR53_16485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR53_16490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHR53_16500	COG1113	amino acid transport
CHR53_16510	COG3681	Belongs to the UPF0597 family
CHR53_16515	COG0516	GMP reductase activity
CHR53_16525	COG5002	protein histidine kinase activity
CHR53_16530	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHR53_16540	COG3409	Peptidoglycan-binding domain 1 protein
CHR53_16540	COG3773	Cell wall hydrolase
CHR53_16550	COG1620	l-lactate permease
CHR53_16560	COG0385	Bile acid
CHR53_16575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHR53_16580	COG2022	thiamine diphosphate biosynthetic process
CHR53_16590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR53_16595	COG0352	thiamine-phosphate diphosphorylase activity
CHR53_16600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHR53_16605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_16610	COG1116	anion transmembrane transporter activity
CHR53_16615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR53_16620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR53_16650	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_16655	COG1346	cytolysis
CHR53_16660	COG1380	Effector of murein hydrolase LrgA
CHR53_16665	COG0583	DNA-binding transcription factor activity
CHR53_16675	COG1114	Component of the transport system for branched-chain amino acids
CHR53_16680	COG0531	amino acid
CHR53_16685	COG1285	pathogenesis
CHR53_16690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHR53_16695	COG1349	DNA-binding transcription factor activity
CHR53_16710	COG0395	ABC-type sugar transport system, permease component
CHR53_16720	COG4143	(ABC) transporter
CHR53_16725	COG0039	L-malate dehydrogenase activity
CHR53_16730	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHR53_16735	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CHR53_16750	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHR53_16755	COG1454	alcohol dehydrogenase
CHR53_16755	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_16760	COG4816	utilization protein
CHR53_16765	COG4302	ethanolamine ammonia-lyase activity
CHR53_16770	COG4303	Ethanolamine ammonia lyase large subunit
CHR53_16780	COG4917	ethanolamine utilization protein
CHR53_16785	COG4810	utilization protein
CHR53_16790	COG3192	ethanolamine utilization protein
CHR53_16805	COG4302	ethanolamine ammonia-lyase activity
CHR53_16810	COG4303	Ethanolamine ammonia lyase large subunit
CHR53_16820	COG0701	Predicted permease
CHR53_16825	COG2271	Major facilitator Superfamily
CHR53_16845	COG0039	L-malate dehydrogenase activity
CHR53_16850	COG0686	Belongs to the AlaDH PNT family
CHR53_16855	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CHR53_16865	COG4869	propanediol catabolic process
CHR53_16870	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHR53_16880	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CHR53_16895	COG1285	pathogenesis
CHR53_16900	COG1349	DNA-binding transcription factor activity
CHR53_16910	COG0477	Major facilitator Superfamily
CHR53_16925	COG3842	ATPase activity
CHR53_16930	COG1840	ABC-type Fe3 transport system, periplasmic component
CHR53_16935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR53_16950	COG0024	Methionine aminopeptidase
CHR53_16955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR53_16960	COG4521	taurine ABC transporter
CHR53_16965	COG1116	anion transmembrane transporter activity
CHR53_16975	COG1113	amino acid transport
CHR53_16990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHR53_16995	COG0686	Belongs to the AlaDH PNT family
CHR53_17000	COG1725	Transcriptional regulator
CHR53_17005	COG0583	DNA-binding transcription factor activity
CHR53_17015	COG1228	amidohydrolase
CHR53_17035	COG3290	protein histidine kinase activity
CHR53_17060	COG0454	-acetyltransferase
CHR53_17075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_17100	COG4948	Mandelate Racemase Muconate Lactonizing
CHR53_17120	COG1695	Transcriptional regulator
CHR53_17130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CHR53_17135	COG1845	cytochrome c oxidase, subunit III
CHR53_17140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR53_17145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR53_17165	COG1960	acyl-CoA dehydrogenase activity
CHR53_17170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHR53_17190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR53_17200	COG1984	allophanate hydrolase subunit 2
CHR53_17210	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CHR53_17260	COG3835	regulator
CHR53_17265	COG0733	neurotransmitter:sodium symporter activity
CHR53_17280	COG3835	regulator
CHR53_17285	COG0028	Belongs to the TPP enzyme family
CHR53_17295	COG0436	Aminotransferase
CHR53_17305	COG5337	Spore coat protein CotH
CHR53_17315	COG0277	FAD linked oxidase domain protein
CHR53_17320	COG0247	lactate metabolic process
CHR53_17325	COG0277	FAD linked oxidase domain protein
CHR53_17335	COG2027	D-alanyl-D-alanine carboxypeptidase
CHR53_17340	COG1388	LysM domain
CHR53_17340	COG3858	chitin binding
CHR53_17360	COG0574	Belongs to the PEP-utilizing enzyme family
CHR53_17360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHR53_17365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CHR53_17370	COG0517	IMP dehydrogenase activity
CHR53_17375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHR53_17430	COG0708	Exodeoxyribonuclease III
CHR53_17435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHR53_17450	COG1657	PFAM Prenyltransferase squalene oxidase
CHR53_17460	COG4413	Urea transporter
CHR53_17470	COG0829	nickel cation binding
CHR53_17475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHR53_17480	COG0830	nickel cation binding
CHR53_17485	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CHR53_17490	COG0804	urea catabolic process
CHR53_17500	COG0831	urea catabolic process
CHR53_17505	COG3663	DNA glycosylase
CHR53_17520	COG1477	protein flavinylation
CHR53_17535	COG0745	RESPONSE REGULATOR receiver
CHR53_17540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_17550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR53_17555	COG3850	Histidine kinase
CHR53_17555	COG5002	protein histidine kinase activity
CHR53_17560	COG0745	RESPONSE REGULATOR receiver
CHR53_17570	COG2720	vancomycin resistance protein
CHR53_17585	COG0726	polysaccharide deacetylase
CHR53_17590	COG2226	methyltransferase
CHR53_17605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_17625	COG2323	membrane
CHR53_17630	COG0697	spore germination
CHR53_17635	COG0833	amino acid
CHR53_17655	COG0017	Asparaginyl-tRNA synthetase
CHR53_17670	COG3973	AAA domain
CHR53_17675	COG2353	YceI-like domain
CHR53_17680	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_17685	COG1937	Protein conserved in bacteria
CHR53_17710	COG0789	Transcriptional regulator
CHR53_17715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR53_17720	COG3594	Acyltransferase
CHR53_17725	COG2404	hydrolase activity, acting on ester bonds
CHR53_17730	COG5002	protein histidine kinase activity
CHR53_17730	COG3850	Histidine kinase
CHR53_17750	COG0527	aspartate kinase activity
CHR53_17760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHR53_17765	COG4120	Belongs to the binding-protein-dependent transport system permease family
CHR53_17780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR53_17790	COG1525	nuclease
CHR53_17800	COG3344	reverse transcriptase
CHR53_17805	COG1368	sulfuric ester hydrolase activity
CHR53_17820	COG0569	domain protein
CHR53_17825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR53_17830	COG2223	nitrite transmembrane transporter activity
CHR53_17835	COG2223	nitrite transmembrane transporter activity
CHR53_17840	COG3383	formate dehydrogenase (NAD+) activity
CHR53_17845	COG0243	molybdopterin cofactor binding
CHR53_17850	COG5002	protein histidine kinase activity
CHR53_17880	COG2181	nitrate reductase activity
CHR53_17890	COG1140	nitrate reductase beta subunit
CHR53_17895	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CHR53_17915	COG1999	signal sequence binding
CHR53_17920	COG0488	(ABC) transporter
CHR53_17940	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR53_17945	COG1686	Belongs to the peptidase S11 family
CHR53_17950	COG0392	lysyltransferase activity
CHR53_17950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CHR53_17965	COG0706	membrane insertase activity
CHR53_17975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHR53_17990	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_18000	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR53_18005	COG0567	Dehydrogenase, E1 component
CHR53_18010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CHR53_18030	COG0134	indole-3-glycerol-phosphate synthase activity
CHR53_18040	COG0512	Glutamine amidotransferase of anthranilate synthase
CHR53_18040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHR53_18050	COG2814	Major facilitator Superfamily
CHR53_18075	COG1278	Cold shock
CHR53_18080	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CHR53_18085	COG3285	dna ligase
CHR53_18085	COG1793	dna ligase
CHR53_18090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CHR53_18115	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_18155	COG3409	Peptidoglycan-binding domain 1 protein
CHR53_18155	COG0793	Belongs to the peptidase S41A family
CHR53_18175	COG4326	sporulation control protein
CHR53_18190	COG4479	Belongs to the UPF0346 family
CHR53_18200	COG1509	lysine 2,3-aminomutase activity
CHR53_18205	COG3829	transcription factor binding
CHR53_18210	COG0456	acetyltransferase
CHR53_18215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_18220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CHR53_18225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CHR53_18230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CHR53_18235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR53_18250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR53_18255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR53_18275	COG2755	lipolytic protein G-D-S-L family
CHR53_18280	COG1999	signal sequence binding
CHR53_18285	COG3852	Histidine kinase
CHR53_18295	COG1307	EDD domain protein, DegV family
CHR53_18310	COG0681	Belongs to the peptidase S26 family
CHR53_18325	COG0805	protein transport
CHR53_18330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHR53_18340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHR53_18355	COG2310	stress, protein
CHR53_18360	COG2310	stress, protein
CHR53_18365	COG3853	Toxic anion resistance protein (TelA)
CHR53_18395	COG0861	Integral membrane protein TerC family
CHR53_18400	COG2310	stress, protein
CHR53_18415	COG1413	lyase activity
CHR53_18420	COG0488	(ABC) transporter
CHR53_18425	COG1418	mRNA catabolic process
CHR53_18430	COG1307	EDD domain protein, DegV family
CHR53_18455	COG1321	iron dependent repressor
CHR53_18470	COG1278	Cold shock
CHR53_18480	COG0328	RNA-DNA hybrid ribonuclease activity
CHR53_18495	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CHR53_18505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR53_18510	COG2897	thiosulfate sulfurtransferase activity
CHR53_18515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CHR53_18520	COG1755	Isoprenylcysteine carboxyl methyltransferase
CHR53_18525	COG3424	synthase
CHR53_18535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CHR53_18540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CHR53_18550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CHR53_18585	COG2151	metal-sulfur cluster biosynthetic enzyme
CHR53_18590	COG1199	ATP-dependent helicase activity
CHR53_18595	COG0116	Belongs to the methyltransferase superfamily
CHR53_18610	COG4474	Belongs to the UPF0398 family
CHR53_18620	COG3359	exonuclease
CHR53_18625	COG1205	dead DEAH box helicase
CHR53_18625	COG1111	helicase
CHR53_18630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR53_18665	COG3331	DNA recombination
CHR53_18670	COG4499	WXG100 protein secretion system (Wss), protein YukC
CHR53_18670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR53_18680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHR53_18685	COG3935	DnaD domain protein
CHR53_18705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHR53_18705	COG1199	ATP-dependent helicase activity
CHR53_18710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CHR53_18715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CHR53_18720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CHR53_18735	COG0438	transferase activity, transferring glycosyl groups
CHR53_18740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CHR53_18745	COG1803	Methylglyoxal synthase
CHR53_18750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHR53_18755	COG1694	Mazg nucleotide pyrophosphohydrolase
CHR53_18760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_18765	COG2738	Putative neutral zinc metallopeptidase
CHR53_18775	COG4347	Protein of unknown function (DUF1405)
CHR53_18785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CHR53_18800	COG5582	Belongs to the UPF0302 family
CHR53_18805	COG0457	Tetratricopeptide repeat
CHR53_18815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHR53_18820	COG0287	Prephenate dehydrogenase
CHR53_18825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CHR53_18830	COG4401	Chorismate mutase type I
CHR53_18835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHR53_18845	COG0105	UTP biosynthetic process
CHR53_18860	COG2226	methyltransferase
CHR53_18865	COG0142	geranyltranstransferase activity
CHR53_18875	COG0302	gtp cyclohydrolase
CHR53_18880	COG0776	regulation of translation
CHR53_18885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CHR53_18900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHR53_18905	COG1160	GTP binding
CHR53_18920	COG1304	FMN binding
CHR53_18925	COG0539	negative regulation of cytoplasmic translation
CHR53_18930	COG2937	Belongs to the GPAT DAPAT family
CHR53_18935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHR53_18945	COG2959	enzyme of heme biosynthesis
CHR53_18950	COG3409	Peptidoglycan-binding domain 1 protein
CHR53_18950	COG3773	Cell wall hydrolase
CHR53_18975	COG2339	peptidase activity
CHR53_18985	COG0492	ferredoxin-NADP+ reductase activity
CHR53_18990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHR53_18995	COG4862	establishment of competence for transformation
CHR53_19000	COG1408	metallophosphoesterase
CHR53_19020	COG3546	catalase activity
CHR53_19035	COG1266	CAAX protease self-immunity
CHR53_19040	COG0514	ATP-dependent DNA helicase (RecQ)
CHR53_19045	COG4955	Helix-turn-helix domain
CHR53_19055	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CHR53_19060	COG3942	CHAP domain
CHR53_19060	COG1388	LysM domain
CHR53_19070	COG1595	DNA-templated transcription, initiation
CHR53_19075	COG5002	protein histidine kinase activity
CHR53_19080	COG0745	RESPONSE REGULATOR receiver
CHR53_19085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHR53_19090	COG1333	cytochrome c biogenesis protein
CHR53_19095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_19100	COG1187	pseudouridine synthase activity
CHR53_19105	COG0700	Nucleoside recognition
CHR53_19110	COG2715	membrane protein required for spore maturation
CHR53_19115	COG1686	Belongs to the peptidase S11 family
CHR53_19120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CHR53_19130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHR53_19145	COG1547	Domain of unknown function (DUF309)
CHR53_19155	COG4086	secreted protein
CHR53_19165	COG0697	spore germination
CHR53_19190	COG2172	sigma factor antagonist activity
CHR53_19200	COG1686	Belongs to the peptidase S11 family
CHR53_19215	COG4974	Belongs to the 'phage' integrase family
CHR53_19225	COG0735	belongs to the Fur family
CHR53_19230	COG1300	Membrane
CHR53_19235	COG1379	DNA repair
CHR53_19250	COG0667	Aldo Keto reductase
CHR53_19260	COG0183	Belongs to the thiolase family
CHR53_19265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHR53_19270	COG1073	alpha beta
CHR53_19290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR53_19305	COG0300	oxidoreductase activity
CHR53_19310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_19315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHR53_19320	COG1215	transferase activity, transferring glycosyl groups
CHR53_19325	COG1902	pentaerythritol trinitrate reductase activity
CHR53_19330	COG1234	tRNA 3'-trailer cleavage
CHR53_19335	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CHR53_19340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR53_19345	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHR53_19350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CHR53_19355	COG0346	lactoylglutathione lyase activity
CHR53_19360	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_19365	COG1126	abc transporter atp-binding protein
CHR53_19370	COG0765	amino acid transport
CHR53_19375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR53_19395	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR53_19395	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR53_19400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR53_19405	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR53_19410	COG0022	dehydrogenase e1 component
CHR53_19415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CHR53_19420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR53_19425	COG3426	butyrate kinase activity
CHR53_19435	COG0280	phosphate acetyltransferase
CHR53_19440	COG3829	transcription factor binding
CHR53_19440	COG3290	protein histidine kinase activity
CHR53_19450	COG0584	glycerophosphoryl diester phosphodiesterase
CHR53_19460	COG0750	zinc metalloprotease
CHR53_19465	COG0497	DNA recombination
CHR53_19475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHR53_19480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CHR53_19490	COG1722	exodeoxyribonuclease VII activity
CHR53_19495	COG1570	exodeoxyribonuclease VII activity
CHR53_19500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHR53_19505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHR53_19510	COG1302	Protein conserved in bacteria
CHR53_19515	COG0439	Biotin carboxylase
CHR53_19520	COG0511	ligase activity, forming carbon-carbon bonds
CHR53_19560	COG3854	ATPases associated with a variety of cellular activities
CHR53_19570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_19580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHR53_19590	COG4555	ABC transporter
CHR53_19610	COG1138	Cytochrome C-type biogenesis protein
CHR53_19615	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CHR53_19625	COG2010	Cytochrome c
CHR53_19640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHR53_19645	COG0006	proline dipeptidase activity
CHR53_19655	COG3872	metal-dependent enzyme
CHR53_19665	COG1752	Esterase of the alpha-beta hydrolase superfamily
CHR53_19670	COG2217	Heavy metal translocating P-type atpase
CHR53_19675	COG2608	mercury ion transmembrane transporter activity
CHR53_19690	COG1388	LysM domain
CHR53_19690	COG0791	NLP P60 protein
CHR53_19695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR53_19700	COG0095	Lipoate-protein ligase
CHR53_19705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_19710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR53_19715	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CHR53_19720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CHR53_19725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR53_19745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_19785	COG4970	Tfp pilus assembly protein FimT
CHR53_19790	COG4537	Required for transformation and DNA binding
CHR53_19795	COG1459	type II secretion system
CHR53_19800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR53_19805	COG1940	carbohydrate kinase activity
CHR53_19820	COG0705	Rhomboid family
CHR53_19820	COG0457	Tetratricopeptide repeat
CHR53_19840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHR53_19865	COG0704	Plays a role in the regulation of phosphate uptake
CHR53_19870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR53_19875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR53_19880	COG0581	inorganic phosphate transmembrane transporter activity
CHR53_19885	COG0573	inorganic phosphate transmembrane transporter activity
CHR53_19890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR53_19900	COG0477	Major facilitator Superfamily
CHR53_19910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CHR53_19915	COG5521	maltodextrose utilization protein MalA
CHR53_19925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CHR53_19930	COG4709	membrane
CHR53_19935	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CHR53_19940	COG0735	belongs to the Fur family
CHR53_19945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHR53_19950	COG1121	(ABC) transporter
CHR53_19960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CHR53_19970	COG0513	Belongs to the DEAD box helicase family
CHR53_19975	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CHR53_19980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHR53_19985	COG2384	SAM-dependent methyltransferase
CHR53_19990	COG2010	Cytochrome c
CHR53_19995	COG1960	acyl-CoA dehydrogenase activity
CHR53_20000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHR53_20005	COG0358	DNA primase activity
CHR53_20015	COG0517	IMP dehydrogenase activity
CHR53_20020	COG0423	glycine-tRNA ligase activity
CHR53_20025	COG1381	Involved in DNA repair and RecF pathway recombination
CHR53_20035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHR53_20040	COG0295	cytidine deaminase activity
CHR53_20045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHR53_20055	COG1480	7TM receptor with intracellular HD hydrolase
CHR53_20060	COG1702	phosphate starvation-inducible protein PhoH
CHR53_20080	COG4864	UPF0365 protein
CHR53_20085	COG1030	water channel activity
CHR53_20090	COG1610	YqeY-like protein
CHR53_20095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR53_20100	COG1283	sodium-dependent phosphate transmembrane transporter activity
CHR53_20105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CHR53_20110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHR53_20115	COG2264	protein methyltransferase activity
CHR53_20120	COG0484	heat shock protein binding
CHR53_20125	COG0443	Heat shock 70 kDa protein
CHR53_20130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHR53_20140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CHR53_20145	COG0481	GTPase activity
CHR53_20155	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHR53_20165	COG0268	Binds directly to 16S ribosomal RNA
CHR53_20170	COG1466	dna polymerase III delta subunit
CHR53_20180	COG2333	competence protein COMEC
CHR53_20180	COG0658	competence protein
CHR53_20185	COG2131	deaminase
CHR53_20190	COG1555	photosystem II stabilization
CHR53_20190	COG1596	polysaccharide export
CHR53_20195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHR53_20200	COG2226	methyltransferase
CHR53_20205	COG0799	negative regulation of ribosome biogenesis
CHR53_20210	COG1713	HD superfamily hydrolase involved in NAD metabolism
CHR53_20215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHR53_20220	COG1534	Rna-binding protein
CHR53_20230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CHR53_20235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CHR53_20245	COG0688	phosphatidylethanolamine metabolic process
CHR53_20250	COG1183	phosphatidylcholine synthase activity
CHR53_20285	COG1024	Enoyl-CoA hydratase
CHR53_20290	COG0183	Belongs to the thiolase family
CHR53_20295	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR53_20300	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_20305	COG1024	Enoyl-CoA hydratase
CHR53_20310	COG1024	Enoyl-CoA hydratase
CHR53_20335	COG3396	Phenylacetate-CoA oxygenase
CHR53_20340	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CHR53_20365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHR53_20375	COG4946	Tricorn protease homolog
CHR53_20375	COG0823	Involved in the tonB-independent uptake of proteins
CHR53_20375	COG1506	peptidase
CHR53_20380	COG0768	penicillin binding
CHR53_20385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR53_20390	COG0572	uridine kinase
CHR53_20410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHR53_20415	COG3906	Belongs to the UPF0473 family
CHR53_20420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHR53_20425	COG4472	Bacterial protein of unknown function (DUF965)
CHR53_20430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHR53_20435	COG0628	permease
CHR53_20455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR53_20465	COG1113	amino acid transport
CHR53_20470	COG0508	dehydrogenase complex catalyzes the overall conversion of
CHR53_20490	COG1522	sequence-specific DNA binding
CHR53_20500	COG1104	cysteine desulfurase activity
CHR53_20505	COG1959	2 iron, 2 sulfur cluster binding
CHR53_20510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHR53_20520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CHR53_20525	COG1131	(ABC) transporter
CHR53_20535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CHR53_20545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHR53_20550	COG0124	histidyl-tRNA synthetase
CHR53_20560	COG3103	Sh3 type 3 domain protein
CHR53_20560	COG4991	sh3 domain protein
CHR53_20560	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHR53_20565	COG1490	D-aminoacyl-tRNA deacylase activity
CHR53_20570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR53_20575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR53_20580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CHR53_20580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHR53_20585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHR53_20585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CHR53_20595	COG2244	polysaccharide biosynthetic process
CHR53_20600	COG2323	membrane
CHR53_20610	COG1862	Preprotein translocase
CHR53_20635	COG0632	four-way junction helicase activity
CHR53_20660	COG1827	regulation of RNA biosynthetic process
CHR53_20665	COG0077	Prephenate dehydratase
CHR53_20670	COG4492	Belongs to the UPF0735 family
CHR53_20675	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHR53_20680	COG3290	protein histidine kinase activity
CHR53_20685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHR53_20690	COG2868	ribosomal protein
CHR53_20700	COG1530	ribonuclease E activity
CHR53_20705	COG1994	Peptidase M50
CHR53_20720	COG2894	cell division
CHR53_20725	COG0850	regulation of cytokinetic process
CHR53_20735	COG1792	Involved in formation and maintenance of cell shape
CHR53_20740	COG1077	Cell shape determining protein MreB Mrl
CHR53_20745	COG2003	Belongs to the UPF0758 family
CHR53_20775	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CHR53_20795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR53_20825	COG3706	GGDEF domain
CHR53_20830	COG0285	dihydrofolate synthase activity
CHR53_20835	COG0525	valine-tRNA ligase activity
CHR53_20855	COG1388	LysM domain
CHR53_20865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CHR53_20870	COG0113	porphobilinogen synthase activity
CHR53_20880	COG0181	hydroxymethylbilane synthase activity
CHR53_20885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CHR53_20905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CHR53_20910	COG0470	DNA polymerase III
CHR53_20910	COG1067	ATP-dependent peptidase activity
CHR53_20920	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHR53_20925	COG0457	Tetratricopeptide repeat
CHR53_20925	COG1477	protein flavinylation
CHR53_20935	COG0622	Phosphoesterase
CHR53_20940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHR53_20950	COG5401	PFAM Sporulation and spore germination
CHR53_20955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHR53_20960	COG1846	Transcriptional regulator
CHR53_20965	COG2197	response regulator
CHR53_20970	COG1523	belongs to the glycosyl hydrolase 13 family
CHR53_20975	COG3764	Sortase (surface protein transpeptidase)
CHR53_20980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CHR53_20985	COG1053	succinate dehydrogenase
CHR53_20990	COG2009	succinate dehydrogenase
CHR53_20995	COG1719	4-vinyl reductase, 4VR
CHR53_21005	COG0322	excinuclease ABC activity
CHR53_21010	COG3118	belongs to the thioredoxin family
CHR53_21015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR53_21020	COG2086	electron transfer activity
CHR53_21025	COG1024	Enoyl-CoA hydratase
CHR53_21030	COG1309	transcriptional regulator
CHR53_21035	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_21045	COG3766	membrane
CHR53_21050	COG1193	negative regulation of DNA recombination
CHR53_21055	COG1796	DNA polymerase
CHR53_21055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CHR53_21060	COG1286	toxin biosynthetic process
CHR53_21065	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CHR53_21070	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHR53_21075	COG2154	pterin-4-alpha-carbinolamine dehydratase
CHR53_21085	COG0072	phenylalanine-tRNA ligase activity
CHR53_21085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR53_21090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHR53_21095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR53_21115	COG2207	Transcriptional regulator
CHR53_21115	COG1609	Transcriptional regulator
CHR53_21120	COG1363	Peptidase, m42
CHR53_21125	COG0589	response to stress
CHR53_21140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHR53_21145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHR53_21150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHR53_21155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHR53_21165	COG1484	DNA-dependent DNA replication
CHR53_21170	COG3611	Membrane attachment protein
CHR53_21175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHR53_21185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CHR53_21195	COG1971	Probably functions as a manganese efflux pump
CHR53_21200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHR53_21205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR53_21205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR53_21210	COG5002	protein histidine kinase activity
CHR53_21215	COG0745	RESPONSE REGULATOR receiver
CHR53_21225	COG0039	L-malate dehydrogenase activity
CHR53_21230	COG0538	isocitrate dehydrogenase activity
CHR53_21235	COG0372	Belongs to the citrate synthase family
CHR53_21240	COG0628	permease
CHR53_21255	COG0825	malonyl-CoA metabolic process
CHR53_21260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHR53_21265	COG2186	Transcriptional regulator
CHR53_21270	COG0281	malic enzyme
CHR53_21275	COG0587	DNA-directed DNA polymerase activity
CHR53_21290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CHR53_21300	COG4109	DRTGG domain
CHR53_21310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CHR53_21315	COG0006	proline dipeptidase activity
CHR53_21330	COG0589	response to stress
CHR53_21350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHR53_21355	COG0827	DNA restriction-modification system
CHR53_21360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CHR53_21365	COG3874	Sporulation protein YtfJ
CHR53_21375	COG1714	RDD family
CHR53_21380	COG0616	signal peptide processing
CHR53_21385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHR53_21390	COG2962	Rard protein
CHR53_21395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR53_21405	COG0301	tRNA thio-modification
CHR53_21410	COG1104	cysteine desulfurase activity
CHR53_21415	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CHR53_21420	COG1309	transcriptional regulator
CHR53_21425	COG1956	GAF domain-containing protein
CHR53_21430	COG0626	cystathionine gamma-synthase activity
CHR53_21435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHR53_21445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHR53_21450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CHR53_21455	COG0454	-acetyltransferase
CHR53_21460	COG0517	IMP dehydrogenase activity
CHR53_21465	COG0123	including yeast histone deacetylase and acetoin utilization protein
CHR53_21475	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CHR53_21475	COG1605	Chorismate mutase
CHR53_21480	COG3118	belongs to the thioredoxin family
CHR53_21485	COG4980	gas vesicle protein
CHR53_21490	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CHR53_21495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHR53_21500	COG1674	ftsk spoiiie
CHR53_21505	COG4848	Belongs to the UPF0354 family
CHR53_21510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_21515	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CHR53_21520	COG1363	Peptidase, m42
CHR53_21530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_21535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHR53_21545	COG0510	thiamine kinase activity
CHR53_21550	COG1523	belongs to the glycosyl hydrolase 13 family
CHR53_21565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_21570	COG1349	DNA-binding transcription factor activity
CHR53_21575	COG1113	amino acid transport
CHR53_21590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR53_21595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CHR53_21605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHR53_21610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHR53_21615	COG1187	pseudouridine synthase activity
CHR53_21620	COG2244	polysaccharide biosynthetic process
CHR53_21625	COG2081	HI0933 family
CHR53_21640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHR53_21645	COG0495	leucyl-tRNA aminoacylation
CHR53_21650	COG2814	Major facilitator Superfamily
CHR53_21655	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CHR53_21675	COG1242	4 iron, 4 sulfur cluster binding
CHR53_21680	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CHR53_21690	COG2267	carboxylic ester hydrolase activity
CHR53_21695	COG0367	asparagine synthase
CHR53_21700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHR53_21715	COG1506	peptidase
CHR53_21720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CHR53_21725	COG1116	anion transmembrane transporter activity
CHR53_21730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR53_21755	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CHR53_21760	COG0288	reversible hydration of carbon dioxide
CHR53_21775	COG4948	Mandelate Racemase Muconate Lactonizing
CHR53_21780	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_21785	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CHR53_21790	COG0596	Alpha beta hydrolase
CHR53_21800	COG1169	isochorismate synthase
CHR53_21805	COG1575	Belongs to the MenA family. Type 1 subfamily
CHR53_21810	COG0058	SHG alpha-glucan phosphorylase activity
CHR53_21815	COG0297	glycogen (starch) synthase activity
CHR53_21820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CHR53_21955	COG1285	pathogenesis
CHR53_21975	COG1115	amino acid carrier protein
CHR53_21980	COG3938	Belongs to the proline racemase family
CHR53_21985	COG3938	Belongs to the proline racemase family
CHR53_21990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR53_21995	COG3829	transcription factor binding
CHR53_21995	COG3290	protein histidine kinase activity
CHR53_22025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHR53_22040	COG0425	Belongs to the sulfur carrier protein TusA family
CHR53_22045	COG0583	DNA-binding transcription factor activity
CHR53_22055	COG5577	PFAM Coat F domain
CHR53_22070	COG5577	PFAM Coat F domain
CHR53_22075	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_22095	COG0083	homoserine kinase activity
CHR53_22100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CHR53_22105	COG0460	homoserine dehydrogenase
CHR53_22110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR53_22125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CHR53_22155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHR53_22160	COG0531	amino acid
CHR53_22165	COG0531	amino acid
CHR53_22170	COG3773	Cell wall hydrolase
CHR53_22175	COG0783	Belongs to the Dps family
CHR53_22180	COG0492	ferredoxin-NADP+ reductase activity
CHR53_22185	COG2233	PERMEase
CHR53_22190	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CHR53_22195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CHR53_22210	COG1349	DNA-binding transcription factor activity
CHR53_22215	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_22215	COG3347	Dehydrogenase
CHR53_22220	COG1069	ribulokinase activity
CHR53_22230	COG1070	Carbohydrate kinase
CHR53_22235	COG0235	Class ii aldolase
CHR53_22240	COG4221	oxidoreductase activity
CHR53_22250	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR53_22255	COG1129	ABC transporter
CHR53_22260	COG1349	DNA-binding transcription factor activity
CHR53_22265	COG4154	Belongs to the RbsD FucU family
CHR53_22270	COG1070	Carbohydrate kinase
CHR53_22275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHR53_22285	COG2706	6-phosphogluconolactonase activity
CHR53_22290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHR53_22295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHR53_22310	COG1215	transferase activity, transferring glycosyl groups
CHR53_22315	COG0438	transferase activity, transferring glycosyl groups
CHR53_22320	COG0728	peptidoglycan biosynthetic process
CHR53_22335	COG0489	protein tyrosine kinase activity
CHR53_22340	COG3944	biosynthesis protein
CHR53_22350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CHR53_22355	COG1086	Polysaccharide biosynthesis protein
CHR53_22360	COG0626	cystathionine gamma-synthase activity
CHR53_22365	COG0626	cystathionine gamma-synthase activity
CHR53_22370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CHR53_22370	COG0646	methionine synthase
CHR53_22375	COG1410	methionine synthase
CHR53_22375	COG0646	methionine synthase
CHR53_22385	COG2814	Major facilitator Superfamily
CHR53_22395	COG1984	allophanate hydrolase subunit 2
CHR53_22400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR53_22405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHR53_22415	COG2814	Major facilitator Superfamily
CHR53_22440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHR53_22450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CHR53_22455	COG1113	amino acid transport
CHR53_22460	COG1280	lysine exporter protein (LysE YggA)
CHR53_22470	COG0463	Glycosyl transferase, family 2
CHR53_22480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CHR53_22495	COG1979	alcohol dehydrogenase
CHR53_22500	COG2155	Conserved Protein
CHR53_22505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR53_22510	COG1098	S1 RNA binding domain
CHR53_22515	COG3620	sequence-specific DNA binding
CHR53_22525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CHR53_22535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHR53_22550	COG2032	superoxide dismutase activity
CHR53_22560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHR53_22570	COG5018	Exonuclease
CHR53_22575	COG2050	protein possibly involved in aromatic compounds catabolism
CHR53_22585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHR53_22595	COG3584	3D domain protein
CHR53_22605	COG1252	NADH dehydrogenase
CHR53_22610	COG0492	ferredoxin-NADP+ reductase activity
CHR53_22615	COG0316	Belongs to the HesB IscA family
CHR53_22625	COG1252	NADH dehydrogenase
CHR53_22630	COG4837	Protein of unknown function (DUF1462)
CHR53_22635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CHR53_22640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHR53_22645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CHR53_22650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHR53_22655	COG0647	UMP catabolic process
CHR53_22660	COG2445	Protein of unknown function DUF86
CHR53_22665	COG3300	MHYT domain
CHR53_22665	COG5001	Diguanylate cyclase
CHR53_22680	COG4470	Protein conserved in bacteria
CHR53_22690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CHR53_22695	COG0739	heme binding
CHR53_22705	COG3377	Domain of unknown function (DUF1805)
CHR53_22710	COG0737	Belongs to the 5'-nucleotidase family
CHR53_22715	COG0730	response to heat
CHR53_22720	COG1801	Protein of unknown function DUF72
CHR53_22725	COG0719	Fe-S assembly protein
CHR53_22730	COG0822	iron-sulfur transferase activity
CHR53_22735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHR53_22740	COG0719	Fe-S assembly protein
CHR53_22745	COG0396	ATPase activity
CHR53_22750	COG1464	Belongs to the NlpA lipoprotein family
CHR53_22755	COG2011	ABC-type metal ion transport system permease component
CHR53_22760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHR53_22775	COG2271	Major facilitator Superfamily
CHR53_22785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CHR53_22790	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CHR53_22795	COG0509	glycine decarboxylation via glycine cleavage system
CHR53_22800	COG1393	Belongs to the ArsC family
CHR53_22805	COG1960	acyl-CoA dehydrogenase activity
CHR53_22810	COG0183	Belongs to the thiolase family
CHR53_22815	COG1024	Enoyl-CoA hydratase
CHR53_22815	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR53_22830	COG1115	amino acid carrier protein
CHR53_22835	COG0772	Belongs to the SEDS family
CHR53_22850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CHR53_22855	COG1910	domain protein
CHR53_22875	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_22880	COG2205	protein histidine kinase activity
CHR53_22885	COG0745	RESPONSE REGULATOR receiver
CHR53_22890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_22895	COG0697	spore germination
CHR53_22900	COG2268	Band 7 protein
CHR53_22905	COG1585	Membrane protein implicated in regulation of membrane protease activity
CHR53_22910	COG1126	abc transporter atp-binding protein
CHR53_22915	COG0765	amino acid transport
CHR53_22920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR53_22935	COG1607	acyl-coa hydrolase
CHR53_22955	COG0628	permease
CHR53_22960	COG0726	polysaccharide deacetylase
CHR53_22995	COG0455	bacterial-type flagellum organization
CHR53_23030	COG5577	PFAM Coat F domain
CHR53_23050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHR53_23060	COG2323	membrane
CHR53_23075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CHR53_23080	COG0557	exoribonuclease II activity
CHR53_23085	COG1647	Serine aminopeptidase, S33
CHR53_23090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHR53_23100	COG0148	phosphopyruvate hydratase activity
CHR53_23105	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CHR53_23115	COG0126	phosphoglycerate kinase activity
CHR53_23125	COG2390	Transcriptional regulator
CHR53_23135	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CHR53_23150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR53_23160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CHR53_23165	COG1660	Displays ATPase and GTPase activities
CHR53_23170	COG1051	belongs to the nudix hydrolase family
CHR53_23175	COG0492	ferredoxin-NADP+ reductase activity
CHR53_23180	COG0457	Tetratricopeptide repeat
CHR53_23185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CHR53_23185	COG0140	phosphoribosyl-ATP diphosphatase activity
CHR53_23190	COG0107	imidazoleglycerol-phosphate synthase activity
CHR53_23195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CHR53_23200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CHR53_23205	COG0131	Imidazoleglycerol-phosphate dehydratase
CHR53_23210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CHR53_23215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CHR53_23220	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CHR53_23230	COG0110	maltose O-acetyltransferase activity
CHR53_23240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CHR53_23250	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHR53_23255	COG1950	PFAM Membrane protein of
CHR53_23260	COG3595	metallopeptidase activity
CHR53_23275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHR53_23280	COG0556	nucleotide-excision repair
CHR53_23285	COG4897	Protein conserved in bacteria
CHR53_23290	COG4145	pantothenate transmembrane transporter activity
CHR53_23295	COG3924	membrane
CHR53_23315	COG3361	conserved protein (COG2071)
CHR53_23325	COG1294	oxidase, subunit
CHR53_23330	COG1271	oxidase subunit
CHR53_23365	COG1309	transcriptional regulator
CHR53_23370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CHR53_23370	COG3291	Pkd domain containing protein
CHR53_23375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR53_23380	COG3409	Peptidoglycan-binding domain 1 protein
CHR53_23380	COG0793	Belongs to the peptidase S41A family
CHR53_23385	COG0791	NLP P60 protein
CHR53_23385	COG3883	PFAM NLP P60 protein
CHR53_23390	COG2177	Part of the ABC transporter FtsEX involved in
CHR53_23395	COG2884	Cell division ATP-binding protein ftsE
CHR53_23405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_23445	COG0653	protein targeting
CHR53_23460	COG5577	PFAM Coat F domain
CHR53_23465	COG1040	competence protein
CHR53_23470	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CHR53_23490	COG1307	EDD domain protein, DegV family
CHR53_23495	COG2197	response regulator
CHR53_23500	COG4585	Histidine kinase
CHR53_23505	COG1739	Uncharacterized protein family UPF0029
CHR53_23510	COG1316	TRANSCRIPTIONal
CHR53_23520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHR53_23525	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CHR53_23530	COG1134	teichoic acid transport
CHR53_23535	COG1682	transport, permease protein
CHR53_23540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHR53_23545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CHR53_23560	COG4193	domain, Protein
CHR53_23565	COG0562	UDP-galactopyranose mutase
CHR53_23570	COG0463	Glycosyl transferase, family 2
CHR53_23585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHR53_23590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHR53_23595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHR53_23595	COG0463	Glycosyl transferase, family 2
CHR53_23605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHR53_23605	COG0463	Glycosyl transferase, family 2
CHR53_23625	COG0737	Belongs to the 5'-nucleotidase family
CHR53_23630	COG1316	TRANSCRIPTIONal
CHR53_23635	COG1404	Belongs to the peptidase S8 family
CHR53_23640	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_23645	COG0737	Belongs to the 5'-nucleotidase family
CHR53_23655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHR53_23670	COG1876	peptidase activity
CHR53_23675	COG3853	Toxic anion resistance protein (TelA)
CHR53_23680	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CHR53_23690	COG0346	lactoylglutathione lyase activity
CHR53_23695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHR53_23710	COG0606	chelatase, subunit chli
CHR53_23725	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CHR53_23735	COG0028	Belongs to the TPP enzyme family
CHR53_23745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_23750	COG1510	regulation of RNA biosynthetic process
CHR53_23755	COG4175	Glycine betaine
CHR53_23755	COG0517	IMP dehydrogenase activity
CHR53_23760	COG4176	ABC-type proline glycine betaine transport system permease component
CHR53_23765	COG2113	Glycine betaine
CHR53_23770	COG0737	Belongs to the 5'-nucleotidase family
CHR53_23785	COG3584	3D domain protein
CHR53_23785	COG1388	LysM domain
CHR53_23790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHR53_23810	COG2252	PERMEase
CHR53_23825	COG0604	alcohol dehydrogenase
CHR53_23860	COG0697	spore germination
CHR53_23865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHR53_23895	COG3142	Participates in the control of copper homeostasis
CHR53_23925	COG1263	PTS System
CHR53_23925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR53_23930	COG1737	Transcriptional regulator
CHR53_23940	COG0561	phosphatase activity
CHR53_23945	COG3835	regulator
CHR53_23950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR53_23955	COG0277	FAD linked oxidase domain protein
CHR53_23960	COG0247	lactate metabolic process
CHR53_23970	COG1737	Transcriptional regulator
CHR53_23975	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CHR53_24000	COG0737	Belongs to the 5'-nucleotidase family
CHR53_24005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHR53_24010	COG2514	catechol 2,3-dioxygenase activity
CHR53_24020	COG3684	Belongs to the aldolase LacD family
CHR53_24035	COG2222	sugar isomerase
CHR53_24040	COG1940	carbohydrate kinase activity
CHR53_24045	COG0395	ABC-type sugar transport system, permease component
CHR53_24050	COG1175	transmembrane transport
CHR53_24065	COG1609	Transcriptional regulator
CHR53_24080	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR53_24085	COG3876	Protein conserved in bacteria
CHR53_24095	COG1404	Belongs to the peptidase S8 family
CHR53_24225	COG4720	Psort location CytoplasmicMembrane, score
CHR53_24235	COG2002	toxin-antitoxin pair type II binding
CHR53_24240	COG0069	glutamate synthase activity
CHR53_24245	COG0069	glutamate synthase activity
CHR53_24250	COG1733	regulation of RNA biosynthetic process
CHR53_24255	COG1063	alcohol dehydrogenase
CHR53_24265	COG2271	Major facilitator Superfamily
CHR53_24270	COG0277	FAD linked oxidase domain protein
CHR53_24280	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CHR53_24285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CHR53_24295	COG1136	(ABC) transporter
CHR53_24305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR53_24320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CHR53_24325	COG1309	transcriptional regulator
CHR53_24340	COG0531	amino acid
CHR53_24345	COG0697	spore germination
CHR53_24355	COG3361	conserved protein (COG2071)
CHR53_24360	COG0366	Alpha amylase catalytic
CHR53_24365	COG3833	ABC-type maltose transport systems, permease component
CHR53_24370	COG1175	transmembrane transport
CHR53_24385	COG1501	Belongs to the glycosyl hydrolase 31 family
CHR53_24390	COG5426	von Willebrand factor, type A
CHR53_24395	COG0395	ABC-type sugar transport system, permease component
CHR53_24400	COG1175	transmembrane transport
CHR53_24430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CHR53_24435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CHR53_24440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR53_24445	COG2186	Transcriptional regulator
CHR53_24450	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CHR53_24465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR53_24470	COG0584	glycerophosphoryl diester phosphodiesterase
CHR53_24475	COG0583	DNA-binding transcription factor activity
CHR53_24480	COG1607	acyl-coa hydrolase
CHR53_24530	COG0318	PFAM AMP-dependent synthetase and ligase
CHR53_24540	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_24555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR53_24560	COG1414	Transcriptional regulator
CHR53_24580	COG1191	sigma factor activity
CHR53_24585	COG0455	bacterial-type flagellum organization
CHR53_24590	COG1419	protein localization to endoplasmic reticulum
CHR53_24595	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHR53_24600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CHR53_24605	COG1684	flagellar biosynthetic protein fliR
CHR53_24610	COG1987	bacterial-type flagellum assembly
CHR53_24615	COG1338	Plays a role in the flagellum-specific transport system
CHR53_24620	COG3190	flagellar
CHR53_24625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR53_24625	COG1776	CheC inhibitor of MCP methylation
CHR53_24635	COG1157	protein secretion by the type III secretion system
CHR53_24645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR53_24650	COG1766	The M ring may be actively involved in energy transduction
CHR53_24655	COG1677	Flagellar hook-basal body complex protein FliE
CHR53_24660	COG1558	bacterial-type flagellum-dependent cell motility
CHR53_24665	COG1815	bacterial-type flagellum-dependent cell motility
CHR53_24670	COG1516	flagellar protein fliS
CHR53_24680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR53_24680	COG1776	CheC inhibitor of MCP methylation
CHR53_24685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CHR53_24690	COG4786	Flagellar basal body rod
CHR53_24695	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CHR53_24710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CHR53_24730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CHR53_24735	COG3328	transposase activity
CHR53_24755	COG4786	Flagellar basal body rod
CHR53_24760	COG4786	Flagellar basal body rod
CHR53_24765	COG1728	Protein conserved in bacteria
CHR53_24770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CHR53_24775	COG1360	Flagellar Motor Protein
CHR53_24785	COG2084	Dehydrogenase
CHR53_24790	COG3622	Belongs to the hyi family
CHR53_24795	COG0683	leucine binding
CHR53_24810	COG0411	ABC transporter
CHR53_24825	COG0011	TIGRFAM Protein of
CHR53_24830	COG1316	TRANSCRIPTIONal
CHR53_24850	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_24855	COG2610	gluconate transmembrane transporter activity
CHR53_24860	COG3829	transcription factor binding
CHR53_24860	COG3290	protein histidine kinase activity
CHR53_24890	COG2197	response regulator
CHR53_24900	COG2072	flavoprotein involved in K transport
CHR53_24920	COG1695	Transcriptional regulator
CHR53_24930	COG0829	nickel cation binding
CHR53_24935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHR53_24940	COG0830	nickel cation binding
CHR53_24945	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CHR53_24950	COG0804	urea catabolic process
CHR53_24955	COG0832	Belongs to the urease beta subunit family
CHR53_24965	COG4413	Urea transporter
CHR53_24970	COG5522	Integral membrane protein (intg_mem_TP0381)
CHR53_24975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR53_24975	COG3153	acetyltransferase
CHR53_24985	COG0179	Fumarylacetoacetate (FAA) hydrolase
CHR53_24990	COG0477	Major facilitator Superfamily
CHR53_25005	COG2211	Major facilitator Superfamily
CHR53_25010	COG0583	DNA-binding transcription factor activity
CHR53_25020	COG0786	glutamate:sodium symporter activity
CHR53_25030	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CHR53_25035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR53_25050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CHR53_25060	COG0784	Response regulator, receiver
CHR53_25065	COG4191	Histidine kinase
CHR53_25080	COG5002	protein histidine kinase activity
CHR53_25090	COG2321	neutral zinc metallopeptidase
CHR53_25100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHR53_25105	COG0295	cytidine deaminase activity
CHR53_25110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHR53_25125	COG0813	purine-nucleoside phosphorylase activity
CHR53_25130	COG2814	Major facilitator Superfamily
CHR53_25140	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHR53_25155	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CHR53_25160	COG3483	tryptophan 2,3-dioxygenase activity
CHR53_25165	COG1113	amino acid transport
CHR53_25170	COG3844	kynureninase activity
CHR53_25180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR53_25185	COG1301	dicarboxylic acid transport
CHR53_25190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR53_25195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_25210	COG0584	glycerophosphoryl diester phosphodiesterase
CHR53_25245	COG2860	membrane
CHR53_25250	COG0484	heat shock protein binding
CHR53_25265	COG1988	membrane-bound metal-dependent
CHR53_25270	COG2824	Alkylphosphonate utilization operon protein PhnA
CHR53_25285	COG0450	alkyl hydroperoxide reductase
CHR53_25290	COG0450	alkyl hydroperoxide reductase
CHR53_25295	COG0667	Aldo Keto reductase
CHR53_25305	COG0628	permease
CHR53_25310	COG1309	transcriptional regulator
CHR53_25315	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_25325	COG0477	Major facilitator Superfamily
CHR53_25345	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_25350	COG2318	DinB family
CHR53_25375	COG1132	(ABC) transporter
CHR53_25380	COG1132	(ABC) transporter
CHR53_25385	COG1940	carbohydrate kinase activity
CHR53_25395	COG2723	6-phospho-beta-galactosidase activity
CHR53_25400	COG4753	response regulator
CHR53_25400	COG2207	Transcriptional regulator
CHR53_25405	COG2972	Histidine kinase
CHR53_25415	COG0395	ABC-type sugar transport system, permease component
CHR53_25420	COG4209	transmembrane transport
CHR53_25445	COG5578	integral membrane protein
CHR53_25455	COG0383	alpha-mannosidase activity
CHR53_25475	COG3291	Pkd domain containing protein
CHR53_25475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CHR53_25480	COG3291	Pkd domain containing protein
CHR53_25480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CHR53_25485	COG1482	cell wall glycoprotein biosynthetic process
CHR53_25495	COG0395	ABC-type sugar transport system, permease component
CHR53_25500	COG1175	transmembrane transport
CHR53_25510	COG2197	response regulator
CHR53_25515	COG2972	Histidine kinase
CHR53_25525	COG3250	beta-galactosidase activity
CHR53_25530	COG3773	Cell wall hydrolase
CHR53_25530	COG3409	Peptidoglycan-binding domain 1 protein
CHR53_25535	COG0330	HflC and HflK could
CHR53_25540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_25565	COG1414	Transcriptional regulator
CHR53_25575	COG1830	Aldolase
CHR53_25580	COG1879	ABC-type sugar transport system periplasmic component
CHR53_25590	COG1172	Belongs to the binding-protein-dependent transport system permease family
CHR53_25605	COG1070	Carbohydrate kinase
CHR53_25615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR53_25650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CHR53_25655	COG4565	transcriptional regulatory protein
CHR53_25660	COG3290	protein histidine kinase activity
CHR53_25670	COG2207	Transcriptional regulator
CHR53_25675	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR53_25680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CHR53_25685	COG2086	electron transfer activity
CHR53_25690	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHR53_25695	COG1960	acyl-CoA dehydrogenase activity
CHR53_25700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CHR53_25705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_25710	COG3800	Transcriptional regulator
CHR53_25710	COG1396	sequence-specific DNA binding
CHR53_25715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR53_25720	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_25745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CHR53_25750	COG2188	Transcriptional regulator
CHR53_25755	COG1994	Peptidase M50
CHR53_25775	COG2814	Major facilitator Superfamily
CHR53_25780	COG2897	thiosulfate sulfurtransferase activity
CHR53_25785	COG1737	Transcriptional regulator
CHR53_25790	COG1473	amidohydrolase
CHR53_25800	COG4948	Mandelate Racemase Muconate Lactonizing
CHR53_25805	COG3949	Membrane
CHR53_25825	COG2066	Belongs to the glutaminase family
CHR53_25830	COG1473	amidohydrolase
CHR53_25835	COG2271	Major facilitator Superfamily
CHR53_25850	COG2188	Transcriptional regulator
CHR53_25855	COG4221	oxidoreductase activity
CHR53_25870	COG2897	thiosulfate sulfurtransferase activity
CHR53_25880	COG1414	Transcriptional regulator
CHR53_25885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_25895	COG4608	Belongs to the ABC transporter superfamily
CHR53_25900	COG0444	Belongs to the ABC transporter superfamily
CHR53_25910	COG0601	transmembrane transport
CHR53_25915	COG0747	negative chemotaxis
CHR53_25920	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CHR53_25925	COG1984	allophanate hydrolase subunit 2
CHR53_25930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CHR53_25935	COG1802	Transcriptional regulator
CHR53_25945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CHR53_25950	COG0477	Major facilitator Superfamily
CHR53_25955	COG4948	Mandelate Racemase Muconate Lactonizing
CHR53_25960	COG1473	amidohydrolase
CHR53_25965	COG4948	Mandelate Racemase Muconate Lactonizing
CHR53_25970	COG4608	Belongs to the ABC transporter superfamily
CHR53_25975	COG0444	Belongs to the ABC transporter superfamily
CHR53_25985	COG0601	transmembrane transport
CHR53_26005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR53_26065	COG1940	carbohydrate kinase activity
CHR53_26075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CHR53_26085	COG0444	Belongs to the ABC transporter superfamily
CHR53_26095	COG0601	transmembrane transport
CHR53_26100	COG0747	negative chemotaxis
CHR53_26120	COG1288	antiporter activity
CHR53_26125	COG1473	amidohydrolase
CHR53_26130	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_26135	COG0028	Belongs to the TPP enzyme family
CHR53_26150	COG1473	amidohydrolase
CHR53_26155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CHR53_26165	COG0436	Aminotransferase
CHR53_26220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHR53_26230	COG0196	riboflavin kinase activity
CHR53_26235	COG0196	riboflavin kinase activity
CHR53_26250	COG0583	DNA-binding transcription factor activity
CHR53_26255	COG1115	amino acid carrier protein
CHR53_26265	COG1929	Belongs to the glycerate kinase type-1 family
CHR53_26270	COG1012	belongs to the aldehyde dehydrogenase family
CHR53_26275	COG4670	ketone body catabolic process
CHR53_26280	COG1454	alcohol dehydrogenase
CHR53_26295	COG0410	ABC transporter
CHR53_26310	COG0559	Belongs to the binding-protein-dependent transport system permease family
CHR53_26325	COG1028	Short-chain dehydrogenase reductase Sdr
CHR53_26330	COG0183	Belongs to the thiolase family
CHR53_26335	COG1609	Transcriptional regulator
CHR53_26340	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR53_26365	COG0778	Nitroreductase
CHR53_26370	COG1733	regulation of RNA biosynthetic process
CHR53_26375	COG4533	DNA binding
CHR53_26385	COG3239	Fatty acid desaturase
CHR53_26390	COG2197	response regulator
CHR53_26400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CHR53_26430	COG0728	peptidoglycan biosynthetic process
CHR53_26445	COG0438	transferase activity, transferring glycosyl groups
CHR53_26460	COG0463	Glycosyl transferase, family 2
CHR53_26475	COG1086	Polysaccharide biosynthesis protein
CHR53_26490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHR53_26495	COG1086	Polysaccharide biosynthesis protein
CHR53_26500	COG4464	protein tyrosine phosphatase activity
CHR53_26505	COG0489	protein tyrosine kinase activity
CHR53_26510	COG3944	biosynthesis protein
CHR53_26520	COG0668	transmembrane transport
CHR53_26535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR53_26535	COG4499	WXG100 protein secretion system (Wss), protein YukC
CHR53_26580	COG2304	oxidoreductase activity
CHR53_26595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHR53_26600	COG1473	amidohydrolase
CHR53_26620	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CHR53_26635	COG1388	LysM domain
CHR53_26635	COG0791	NLP P60 protein
CHR53_26640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR53_26650	COG2610	gluconate transmembrane transporter activity
CHR53_26655	COG1929	Belongs to the glycerate kinase type-1 family
CHR53_26660	COG3835	regulator
CHR53_26680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CHR53_26685	COG3584	3D domain protein
CHR53_26685	COG3583	domain protein
CHR53_26725	COG3695	enzyme binding
CHR53_26730	COG0768	penicillin binding
CHR53_26735	COG0739	heme binding
CHR53_26745	COG2385	sporulation resulting in formation of a cellular spore
CHR53_26760	COG4836	Membrane
CHR53_26780	COG2261	transglycosylase associated protein
CHR53_26790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CHR53_26795	COG2205	protein histidine kinase activity
CHR53_26795	COG0784	Response regulator, receiver
CHR53_26800	COG0783	Belongs to the Dps family
CHR53_26815	COG2208	phosphoserine phosphatase activity
CHR53_26820	COG1191	sigma factor activity
CHR53_26825	COG2172	sigma factor antagonist activity
CHR53_26835	COG2814	Major facilitator Superfamily
CHR53_26840	COG1846	Transcriptional regulator
CHR53_26845	COG1619	proteins homologs of microcin C7 resistance protein MccF
CHR53_26870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHR53_26890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CHR53_26910	COG0598	Magnesium transport protein CorA
CHR53_26935	COG0477	Major facilitator Superfamily
CHR53_26945	COG1253	flavin adenine dinucleotide binding
CHR53_26950	COG0668	transmembrane transport
CHR53_26965	COG1007	ATP synthesis coupled electron transport
CHR53_26975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CHR53_26980	COG0713	ATP synthesis coupled electron transport
CHR53_26985	COG0839	Belongs to the complex I subunit 6 family
CHR53_26995	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CHR53_27000	COG0649	NAD binding
CHR53_27005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR53_27010	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR53_27015	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CHR53_27025	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHR53_27030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHR53_27035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHR53_27040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHR53_27045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHR53_27050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHR53_27055	COG0356	it plays a direct role in the translocation of protons across the membrane
CHR53_27070	COG1404	Belongs to the peptidase S8 family
CHR53_27080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHR53_27095	COG0698	ribose 5-phosphate isomerase
CHR53_27105	COG1971	Probably functions as a manganese efflux pump
CHR53_27110	COG0009	L-threonylcarbamoyladenylate synthase
CHR53_27130	COG2890	protein-(glutamine-N5) methyltransferase activity
CHR53_27135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHR53_27145	COG1435	thymidine kinase activity
CHR53_27155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CHR53_27160	COG1494	fructose-1,6-bisphosphatase
CHR53_27165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHR53_27170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CHR53_27175	COG0191	fructose-bisphosphate aldolase activity
CHR53_27180	COG2204	response regulator
CHR53_27185	COG4821	SIS domain
CHR53_27190	COG0504	CTP synthase activity
CHR53_27195	COG3343	RNA polymerase activity
CHR53_27200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR53_27200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CHR53_27200	COG1703	isobutyryl-CoA mutase activity
CHR53_27210	COG1960	acyl-CoA dehydrogenase activity
CHR53_27215	COG1960	acyl-CoA dehydrogenase activity
CHR53_27220	COG1250	3-hydroxyacyl-CoA dehydrogenase
CHR53_27225	COG0183	Belongs to the thiolase family
CHR53_27230	COG0247	lactate metabolic process
CHR53_27230	COG2181	nitrate reductase activity
CHR53_27235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHR53_27250	COG4506	Protein conserved in bacteria
CHR53_27255	COG0010	Belongs to the arginase family
CHR53_27260	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CHR53_27265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR53_27275	COG1994	Peptidase M50
CHR53_27290	COG3465	dGTPase activity
CHR53_27295	COG1078	dGTPase activity
CHR53_27315	COG0280	phosphate acetyltransferase
CHR53_27330	COG2363	Small membrane protein
CHR53_27340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CHR53_27350	COG0314	molybdopterin synthase activity
CHR53_27355	COG0303	'Molybdopterin
CHR53_27360	COG0303	'Molybdopterin
CHR53_27380	COG0437	4 iron, 4 sulfur cluster binding
CHR53_27390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CHR53_27395	COG0351	phosphomethylpyrimidine kinase
CHR53_27415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CHR53_27455	COG1131	(ABC) transporter
CHR53_27465	COG2133	pyrroloquinoline quinone binding
CHR53_27470	COG0561	phosphatase activity
CHR53_27485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHR53_27500	COG0411	ABC transporter
CHR53_27520	COG0477	Major facilitator Superfamily
CHR53_27525	COG1132	(ABC) transporter
CHR53_27530	COG1132	(ABC) transporter
CHR53_27555	COG0003	Pfam Anion-transporting ATPase
CHR53_27590	COG1131	(ABC) transporter
CHR53_27605	COG2195	Cleaves the N-terminal amino acid of tripeptides
CHR53_27615	COG0069	glutamate synthase activity
CHR53_27620	COG0583	DNA-binding transcription factor activity
CHR53_27625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CHR53_27650	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_27655	COG1376	ErfK ybiS ycfS ynhG family protein
CHR53_27660	COG0402	S-adenosylhomocysteine deaminase activity
CHR53_27665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CHR53_27670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CHR53_27685	COG3584	3D domain protein
CHR53_27685	COG1388	LysM domain
CHR53_27690	COG2031	fatty acid transporter
CHR53_27695	COG1051	belongs to the nudix hydrolase family
CHR53_27705	COG4260	virion core protein, lumpy skin disease virus
CHR53_27710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CHR53_27715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHR53_27720	COG1842	Phage shock protein A
CHR53_27750	COG2133	pyrroloquinoline quinone binding
CHR53_27755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CHR53_27760	COG0157	Belongs to the NadC ModD family
CHR53_27765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CHR53_27775	COG2814	Major facilitator Superfamily
CHR53_27790	COG0579	oxidoreductase
CHR53_27815	COG0577	efflux transmembrane transporter activity
CHR53_27820	COG1136	(ABC) transporter
CHR53_27830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CHR53_27865	COG2391	methyltransferase activity
CHR53_27920	COG0778	Nitroreductase
CHR53_27925	COG1187	pseudouridine synthase activity
CHR53_27930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR53_27940	COG2169	Transcriptional regulator
CHR53_27950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHR53_27960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR53_27965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHR53_27970	COG4853	Protein conserved in bacteria
CHR53_27975	COG4863	YycH protein
CHR53_27980	COG5002	protein histidine kinase activity
CHR53_27985	COG0745	RESPONSE REGULATOR receiver
CHR53_27990	COG0739	heme binding
CHR53_27990	COG1196	nuclear chromosome segregation
CHR53_27990	COG0741	lytic transglycosylase activity
CHR53_28020	COG0305	Participates in initiation and elongation during chromosome replication
CHR53_28025	COG0359	binds to the 23S rRNA
CHR53_28030	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CHR53_28035	COG4241	membrane
CHR53_28040	COG1910	domain protein
CHR53_28045	COG0725	ABC transporter, periplasmic molybdate-binding protein
CHR53_28050	COG4149	molybdate abc transporter
CHR53_28055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHR53_28065	COG0360	Binds together with S18 to 16S ribosomal RNA
CHR53_28070	COG0012	GTP binding
CHR53_28075	COG4193	domain, Protein
CHR53_28080	COG0243	molybdopterin cofactor binding
CHR53_28085	COG4481	Protein conserved in bacteria
CHR53_28090	COG0668	transmembrane transport
CHR53_28105	COG1475	DNA binding
CHR53_28110	COG1192	Involved in chromosome partitioning
CHR53_28115	COG1475	DNA binding
CHR53_28120	COG0357	Ribosomal RNA small subunit methyltransferase G
CHR53_28125	COG0445	tRNA wobble uridine modification
CHR53_28130	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHR53_28135	COG1847	R3H domain protein
CHR53_28145	COG0594	ribonuclease P activity