locus-tag	class	description
MLA2C4_00010	COG0592	DNA-directed DNA polymerase activity
MLA2C4_00015	COG2501	S4 domain
MLA2C4_00025	COG0187	DNA topoisomerase II activity
MLA2C4_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLA2C4_00065	COG0517	IMP dehydrogenase activity
MLA2C4_00065	COG0516	GMP reductase activity
MLA2C4_00070	COG1686	Belongs to the peptidase S11 family
MLA2C4_00100	COG1428	Deoxynucleoside kinase
MLA2C4_00105	COG1428	Deoxynucleoside kinase
MLA2C4_00110	COG1335	isochorismatase
MLA2C4_00115	COG0590	tRNA wobble adenosine to inosine editing
MLA2C4_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLA2C4_00180	COG1982	Orn Lys Arg decarboxylase major
MLA2C4_00190	COG0470	DNA polymerase III
MLA2C4_00195	COG1774	PSP1 C-terminal conserved region
MLA2C4_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MLA2C4_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLA2C4_00220	COG2002	toxin-antitoxin pair type II binding
MLA2C4_00230	COG0084	hydrolase, TatD family'
MLA2C4_00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLA2C4_00250	COG4466	Protein conserved in bacteria
MLA2C4_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLA2C4_00270	COG0251	oxidation-reduction process
MLA2C4_00275	COG2088	sporulation resulting in formation of a cellular spore
MLA2C4_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLA2C4_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLA2C4_00305	COG2002	toxin-antitoxin pair type II binding
MLA2C4_00310	COG2244	polysaccharide biosynthetic process
MLA2C4_00315	COG3956	TIGRFAM MazG family protein
MLA2C4_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MLA2C4_00340	COG1098	S1 RNA binding domain
MLA2C4_00355	COG2208	phosphoserine phosphatase activity
MLA2C4_00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLA2C4_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MLA2C4_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLA2C4_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
MLA2C4_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLA2C4_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLA2C4_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLA2C4_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLA2C4_00420	COG1396	sequence-specific DNA binding
MLA2C4_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLA2C4_00515	COG3880	PFAM UvrB UvrC protein
MLA2C4_00525	COG0542	response to heat
MLA2C4_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLA2C4_00540	COG4956	integral membrane protein (PIN domain superfamily)
MLA2C4_00560	COG1045	serine acetyltransferase
MLA2C4_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLA2C4_00580	COG3688	RNA-binding protein containing a PIN domain
MLA2C4_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MLA2C4_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MLA2C4_00600	COG0250	Participates in transcription elongation, termination and antitermination
MLA2C4_00625	COG2813	Specifically methylates the guanine in position
MLA2C4_00640	COG1358	cellular component organization or biogenesis
MLA2C4_00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLA2C4_00775	COG0201	protein transport
MLA2C4_00785	COG0024	Methionine aminopeptidase
MLA2C4_00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MLA2C4_00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLA2C4_00835	COG0101	tRNA pseudouridine synthase activity
MLA2C4_00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_00860	COG0489	protein tyrosine kinase activity
MLA2C4_00870	COG2194	sulfuric ester hydrolase activity
MLA2C4_00875	COG0726	polysaccharide deacetylase
MLA2C4_00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLA2C4_00960	COG4856	YbbR-like protein
MLA2C4_01010	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_01015	COG2011	ABC-type metal ion transport system permease component
MLA2C4_01025	COG1464	Belongs to the NlpA lipoprotein family
MLA2C4_01040	COG0277	FAD linked oxidase domain protein
MLA2C4_01045	COG2271	Major facilitator Superfamily
MLA2C4_01055	COG2814	Major facilitator Superfamily
MLA2C4_01080	COG0601	transmembrane transport
MLA2C4_01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLA2C4_01090	COG0444	Belongs to the ABC transporter superfamily
MLA2C4_01095	COG4608	Belongs to the ABC transporter superfamily
MLA2C4_01100	COG4166	transmembrane transport
MLA2C4_01110	COG2207	Transcriptional regulator
MLA2C4_01125	COG4166	transmembrane transport
MLA2C4_01130	COG4166	transmembrane transport
MLA2C4_01135	COG0656	L-ascorbic acid biosynthetic process
MLA2C4_01150	COG4149	molybdate abc transporter
MLA2C4_01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
MLA2C4_01160	COG1910	domain protein
MLA2C4_01175	COG0697	spore germination
MLA2C4_01190	COG0204	Acyl-transferase
MLA2C4_01205	COG1609	Transcriptional regulator
MLA2C4_01215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_01225	COG0084	hydrolase, TatD family'
MLA2C4_01235	COG5298	Protein conserved in bacteria
MLA2C4_01255	COG0488	(ABC) transporter
MLA2C4_01260	COG4585	Histidine kinase
MLA2C4_01265	COG2197	response regulator
MLA2C4_01270	COG1131	(ABC) transporter
MLA2C4_01275	COG1511	domain protein
MLA2C4_01275	COG0842	Transport permease protein
MLA2C4_01280	COG0842	Transport permease protein
MLA2C4_01290	COG0747	negative chemotaxis
MLA2C4_01295	COG0747	negative chemotaxis
MLA2C4_01300	COG0601	transmembrane transport
MLA2C4_01310	COG0444	Belongs to the ABC transporter superfamily
MLA2C4_01315	COG4608	Belongs to the ABC transporter superfamily
MLA2C4_01320	COG0561	phosphatase activity
MLA2C4_01355	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MLA2C4_01360	COG0179	Fumarylacetoacetate (FAA) hydrolase
MLA2C4_01370	COG0531	amino acid
MLA2C4_01385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MLA2C4_01395	COG4294	response to UV
MLA2C4_01400	COG0705	Rhomboid family
MLA2C4_01410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MLA2C4_01415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLA2C4_01420	COG0864	Transcriptional regulator
MLA2C4_01425	COG2337	Toxic component of a toxin-antitoxin (TA) module
MLA2C4_01430	COG2183	response to ionizing radiation
MLA2C4_01530	COG0802	atpase or kinase
MLA2C4_01535	COG1214	PFAM Peptidase M22, glycoprotease
MLA2C4_01540	COG0456	acetyltransferase
MLA2C4_01550	COG0488	(ABC) transporter
MLA2C4_01565	COG1266	CAAX protease self-immunity
MLA2C4_01575	COG0459	protein refolding
MLA2C4_01595	COG2252	PERMEase
MLA2C4_01605	COG5002	protein histidine kinase activity
MLA2C4_01630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MLA2C4_01675	COG1215	transferase activity, transferring glycosyl groups
MLA2C4_01695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_01700	COG0506	proline dehydrogenase activity
MLA2C4_01720	COG0697	spore germination
MLA2C4_01745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLA2C4_01750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLA2C4_01755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLA2C4_01765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLA2C4_01780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLA2C4_01790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLA2C4_01800	COG0151	Belongs to the GarS family
MLA2C4_01830	COG0210	DNA helicase
MLA2C4_01840	COG4851	CamS sex pheromone cAM373 precursor
MLA2C4_01855	COG1335	isochorismatase
MLA2C4_01870	COG2011	ABC-type metal ion transport system permease component
MLA2C4_01890	COG0003	Pfam Anion-transporting ATPase
MLA2C4_01895	COG1846	Transcriptional regulator
MLA2C4_01900	COG4682	membrane
MLA2C4_01920	COG1597	lipid kinase activity
MLA2C4_01925	COG0546	phosphoglycolate phosphatase activity
MLA2C4_01930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLA2C4_01940	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_01945	COG2076	Multidrug Resistance protein
MLA2C4_01950	COG2309	aminopeptidase activity
MLA2C4_01965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_01975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLA2C4_01980	COG5002	protein histidine kinase activity
MLA2C4_01985	COG4807	Protein conserved in bacteria
MLA2C4_02015	COG1473	amidohydrolase
MLA2C4_02030	COG0450	alkyl hydroperoxide reductase
MLA2C4_02035	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLA2C4_02045	COG0235	Class ii aldolase
MLA2C4_02055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_02060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_02065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_02090	COG0166	Belongs to the GPI family
MLA2C4_02135	COG3541	Predicted nucleotidyltransferase
MLA2C4_02140	COG2814	Major facilitator Superfamily
MLA2C4_02145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLA2C4_02145	COG0723	plastoquinol--plastocyanin reductase activity
MLA2C4_02155	COG0765	amino acid transport
MLA2C4_02160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLA2C4_02180	COG0840	transmembrane signaling receptor activity
MLA2C4_02190	COG0366	Alpha amylase catalytic
MLA2C4_02195	COG2190	(PTS) system
MLA2C4_02195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLA2C4_02195	COG1263	PTS System
MLA2C4_02240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLA2C4_02255	COG4152	abc transporter atp-binding protein
MLA2C4_02260	COG1668	transmembrane transport
MLA2C4_02290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MLA2C4_02305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLA2C4_02315	COG1116	anion transmembrane transporter activity
MLA2C4_02325	COG0488	(ABC) transporter
MLA2C4_02375	COG2270	Major facilitator Superfamily
MLA2C4_02405	COG2310	stress, protein
MLA2C4_02410	COG2310	stress, protein
MLA2C4_02415	COG2310	stress, protein
MLA2C4_02420	COG0861	Integral membrane protein TerC family
MLA2C4_02430	COG3853	Toxic anion resistance protein (TelA)
MLA2C4_02445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLA2C4_02455	COG1295	ribonuclease BN
MLA2C4_02460	COG2217	Heavy metal translocating P-type atpase
MLA2C4_02465	COG0697	spore germination
MLA2C4_02475	COG0681	Belongs to the peptidase S26 family
MLA2C4_02485	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_02500	COG3871	stress protein (general stress protein 26)
MLA2C4_02510	COG0387	Pfam Sodium calcium exchanger
MLA2C4_02520	COG0535	radical SAM domain protein
MLA2C4_02540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLA2C4_02560	COG3829	transcription factor binding
MLA2C4_02570	COG0833	amino acid
MLA2C4_02575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MLA2C4_02595	COG2066	Belongs to the glutaminase family
MLA2C4_02600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLA2C4_02600	COG1263	PTS System
MLA2C4_02605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MLA2C4_02625	COG0463	Glycosyl transferase, family 2
MLA2C4_02635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLA2C4_02635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLA2C4_02640	COG0463	Glycosyl transferase, family 2
MLA2C4_02650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MLA2C4_02670	COG1228	amidohydrolase
MLA2C4_02675	COG1090	epimerase
MLA2C4_02705	COG1988	membrane-bound metal-dependent
MLA2C4_02710	COG1194	a g-specific adenine glycosylase
MLA2C4_02740	COG1132	(ABC) transporter
MLA2C4_02745	COG4129	membrane
MLA2C4_02750	COG0070	glutamate synthase
MLA2C4_02750	COG0069	glutamate synthase activity
MLA2C4_02750	COG0067	glutamate synthase
MLA2C4_02760	COG4555	ABC transporter
MLA2C4_02780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLA2C4_02785	COG0735	belongs to the Fur family
MLA2C4_02900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MLA2C4_02930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLA2C4_02940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MLA2C4_02950	COG2766	serine protein kinase
MLA2C4_02970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MLA2C4_02980	COG1585	Membrane protein implicated in regulation of membrane protease activity
MLA2C4_02985	COG2268	Band 7 protein
MLA2C4_02995	COG3290	protein histidine kinase activity
MLA2C4_03000	COG4565	transcriptional regulatory protein
MLA2C4_03005	COG2851	Citrate transporter
MLA2C4_03035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MLA2C4_03040	COG0745	RESPONSE REGULATOR receiver
MLA2C4_03045	COG5002	protein histidine kinase activity
MLA2C4_03055	COG4990	cell redox homeostasis
MLA2C4_03065	COG3290	protein histidine kinase activity
MLA2C4_03070	COG4565	transcriptional regulatory protein
MLA2C4_03075	COG3493	citrate carrier protein
MLA2C4_03080	COG0281	malic enzyme
MLA2C4_03090	COG0697	spore germination
MLA2C4_03095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_03105	COG5002	protein histidine kinase activity
MLA2C4_03110	COG0745	RESPONSE REGULATOR receiver
MLA2C4_03115	COG0454	-acetyltransferase
MLA2C4_03115	COG0456	acetyltransferase
MLA2C4_03120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLA2C4_03125	COG3383	formate dehydrogenase (NAD+) activity
MLA2C4_03130	COG2427	Protein of unknown function (DUF1641)
MLA2C4_03145	COG0531	amino acid
MLA2C4_03150	COG0640	Transcriptional regulator
MLA2C4_03155	COG2217	Heavy metal translocating P-type atpase
MLA2C4_03160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLA2C4_03170	COG3227	Zinc metalloprotease (Elastase)
MLA2C4_03190	COG2720	vancomycin resistance protein
MLA2C4_03195	COG1316	TRANSCRIPTIONal
MLA2C4_03200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_03205	COG0346	lactoylglutathione lyase activity
MLA2C4_03210	COG1253	flavin adenine dinucleotide binding
MLA2C4_03215	COG1027	Aspartate ammonia-lyase
MLA2C4_03220	COG1620	l-lactate permease
MLA2C4_03235	COG3104	oligopeptide transport
MLA2C4_03240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_03245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_03250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_03260	COG2226	methyltransferase
MLA2C4_03265	COG0156	8-amino-7-oxononanoate synthase activity
MLA2C4_03270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLA2C4_03280	COG4548	von Willebrand factor, type A
MLA2C4_03285	COG0714	Associated with various cellular activities
MLA2C4_03290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLA2C4_03310	COG0531	amino acid
MLA2C4_03315	COG2188	Transcriptional regulator
MLA2C4_03320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLA2C4_03320	COG1263	PTS System
MLA2C4_03325	COG0366	Alpha amylase catalytic
MLA2C4_03340	COG0697	spore germination
MLA2C4_03345	COG4585	Histidine kinase
MLA2C4_03350	COG2197	response regulator
MLA2C4_03355	COG1404	Belongs to the peptidase S8 family
MLA2C4_03370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLA2C4_03375	COG1115	amino acid carrier protein
MLA2C4_03380	COG1126	abc transporter atp-binding protein
MLA2C4_03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLA2C4_03390	COG0765	amino acid transport
MLA2C4_03395	COG0765	amino acid transport
MLA2C4_03400	COG0833	amino acid
MLA2C4_03425	COG2378	regulation of single-species biofilm formation
MLA2C4_03430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLA2C4_03435	COG5002	protein histidine kinase activity
MLA2C4_03450	COG0659	secondary active sulfate transmembrane transporter activity
MLA2C4_03475	COG0601	transmembrane transport
MLA2C4_03480	COG4608	Belongs to the ABC transporter superfamily
MLA2C4_03490	COG2271	Major facilitator Superfamily
MLA2C4_03495	COG1846	Transcriptional regulator
MLA2C4_03500	COG0477	Major facilitator Superfamily
MLA2C4_03505	COG1609	Transcriptional regulator
MLA2C4_03510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLA2C4_03520	COG1129	ABC transporter
MLA2C4_03525	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLA2C4_03530	COG1879	ABC-type sugar transport system periplasmic component
MLA2C4_03535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLA2C4_03555	COG1063	alcohol dehydrogenase
MLA2C4_03570	COG3568	Endonuclease Exonuclease Phosphatase
MLA2C4_03600	COG0840	transmembrane signaling receptor activity
MLA2C4_03605	COG3584	3D domain protein
MLA2C4_03605	COG3583	domain protein
MLA2C4_03610	COG1476	TRANSCRIPTIONal
MLA2C4_03630	COG3104	oligopeptide transport
MLA2C4_03635	COG1114	Component of the transport system for branched-chain amino acids
MLA2C4_03650	COG1113	amino acid transport
MLA2C4_03655	COG2252	PERMEase
MLA2C4_03670	COG2153	protein acetylation
MLA2C4_03680	COG0475	glutathione-regulated potassium exporter activity
MLA2C4_03680	COG0569	domain protein
MLA2C4_03690	COG1845	cytochrome c oxidase, subunit III
MLA2C4_03695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLA2C4_03700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MLA2C4_03705	COG0833	amino acid
MLA2C4_03710	COG4990	cell redox homeostasis
MLA2C4_03725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLA2C4_03730	COG0697	spore germination
MLA2C4_03735	COG0531	amino acid
MLA2C4_03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MLA2C4_03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MLA2C4_03755	COG1918	ferrous iron import across plasma membrane
MLA2C4_03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MLA2C4_03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MLA2C4_03765	COG0573	inorganic phosphate transmembrane transporter activity
MLA2C4_03770	COG0581	inorganic phosphate transmembrane transporter activity
MLA2C4_03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLA2C4_03900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MLA2C4_03920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLA2C4_03925	COG1116	anion transmembrane transporter activity
MLA2C4_03930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLA2C4_03935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLA2C4_03940	COG0352	thiamine-phosphate diphosphorylase activity
MLA2C4_03945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLA2C4_03950	COG2104	thiamine diphosphate biosynthetic process
MLA2C4_03960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MLA2C4_03965	COG0351	phosphomethylpyrimidine kinase
MLA2C4_04005	COG2205	protein histidine kinase activity
MLA2C4_04010	COG2814	Major facilitator Superfamily
MLA2C4_04015	COG1846	Transcriptional regulator
MLA2C4_04040	COG1136	(ABC) transporter
MLA2C4_04050	COG2252	PERMEase
MLA2C4_04055	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_04115	COG0778	Nitroreductase
MLA2C4_04130	COG2201	protein-glutamate methylesterase activity
MLA2C4_04160	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MLA2C4_04160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MLA2C4_04165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MLA2C4_04240	COG3591	Belongs to the peptidase S1B family
MLA2C4_04265	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLA2C4_04270	COG1937	Protein conserved in bacteria
MLA2C4_04280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLA2C4_04285	COG0425	Belongs to the sulfur carrier protein TusA family
MLA2C4_04290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLA2C4_04290	COG0425	Belongs to the sulfur carrier protein TusA family
MLA2C4_04295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLA2C4_04300	COG2210	Belongs to the sulfur carrier protein TusA family
MLA2C4_04305	COG0730	response to heat
MLA2C4_04315	COG1316	TRANSCRIPTIONal
MLA2C4_04320	COG0604	alcohol dehydrogenase
MLA2C4_04325	COG1283	sodium-dependent phosphate transmembrane transporter activity
MLA2C4_04330	COG2814	Major facilitator Superfamily
MLA2C4_04345	COG3711	transcriptional antiterminator
MLA2C4_04345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLA2C4_04350	COG1447	Phosphotransferase system cellobiose-specific component IIA
MLA2C4_04355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MLA2C4_04375	COG1388	LysM domain
MLA2C4_04375	COG3584	3D domain protein
MLA2C4_04380	COG0577	efflux transmembrane transporter activity
MLA2C4_04385	COG1136	(ABC) transporter
MLA2C4_04395	COG5522	Integral membrane protein (intg_mem_TP0381)
MLA2C4_04410	COG1114	Component of the transport system for branched-chain amino acids
MLA2C4_04415	COG3546	catalase activity
MLA2C4_04450	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_04480	COG0531	amino acid
MLA2C4_04490	COG0475	glutathione-regulated potassium exporter activity
MLA2C4_04500	COG1737	Transcriptional regulator
MLA2C4_04510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLA2C4_04510	COG1263	PTS System
MLA2C4_04520	COG2259	Doxx family
MLA2C4_04535	COG0697	spore germination
MLA2C4_04540	COG1522	sequence-specific DNA binding
MLA2C4_04560	COG2076	Multidrug Resistance protein
MLA2C4_04565	COG2076	Multidrug Resistance protein
MLA2C4_04570	COG1309	transcriptional regulator
MLA2C4_04575	COG2814	Major facilitator Superfamily
MLA2C4_04580	COG1733	regulation of RNA biosynthetic process
MLA2C4_04590	COG2249	NAD(P)H dehydrogenase (quinone) activity
MLA2C4_04600	COG4533	DNA binding
MLA2C4_04605	COG2211	Major facilitator Superfamily
MLA2C4_04615	COG0693	protein deglycase activity
MLA2C4_04625	COG0531	amino acid
MLA2C4_04630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MLA2C4_04635	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_04645	COG1132	(ABC) transporter
MLA2C4_04650	COG1132	(ABC) transporter
MLA2C4_04660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLA2C4_04665	COG0765	amino acid transport
MLA2C4_04670	COG1126	abc transporter atp-binding protein
MLA2C4_04685	COG0189	ligase activity
MLA2C4_04715	COG0028	Belongs to the TPP enzyme family
MLA2C4_04720	COG3527	Alpha-acetolactate decarboxylase
MLA2C4_04735	COG0561	phosphatase activity
MLA2C4_04745	COG3409	Peptidoglycan-binding domain 1 protein
MLA2C4_04745	COG5632	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_04750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MLA2C4_04755	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_04765	COG0659	secondary active sulfate transmembrane transporter activity
MLA2C4_04780	COG0653	protein targeting
MLA2C4_04785	COG2244	polysaccharide biosynthetic process
MLA2C4_04795	COG0860	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_04815	COG1696	Membrane protein involved in D-alanine export
MLA2C4_04830	COG1024	Enoyl-CoA hydratase
MLA2C4_04850	COG1363	Peptidase, m42
MLA2C4_04910	COG0477	Major facilitator Superfamily
MLA2C4_04915	COG3290	protein histidine kinase activity
MLA2C4_04920	COG4565	transcriptional regulatory protein
MLA2C4_04925	COG3181	Tripartite tricarboxylate transporter family receptor
MLA2C4_04985	COG0305	Participates in initiation and elongation during chromosome replication
MLA2C4_05005	COG0305	Participates in initiation and elongation during chromosome replication
MLA2C4_05030	COG0477	Major facilitator Superfamily
MLA2C4_05080	COG2226	methyltransferase
MLA2C4_05100	COG3711	transcriptional antiterminator
MLA2C4_05105	COG2190	(PTS) system
MLA2C4_05105	COG1263	PTS System
MLA2C4_05105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLA2C4_05110	COG2723	6-phospho-beta-galactosidase activity
MLA2C4_05120	COG1183	phosphatidylcholine synthase activity
MLA2C4_05135	COG2814	Major facilitator Superfamily
MLA2C4_05140	COG0640	Transcriptional regulator
MLA2C4_05170	COG2376	Dihydroxyacetone kinase
MLA2C4_05185	COG2376	Dihydroxyacetone kinase
MLA2C4_05195	COG1959	2 iron, 2 sulfur cluster binding
MLA2C4_05245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLA2C4_05270	COG0596	Alpha beta hydrolase
MLA2C4_05320	COG1191	sigma factor activity
MLA2C4_05330	COG2208	phosphoserine phosphatase activity
MLA2C4_05335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MLA2C4_05340	COG0784	Response regulator, receiver
MLA2C4_05340	COG2205	protein histidine kinase activity
MLA2C4_05340	COG5002	protein histidine kinase activity
MLA2C4_05380	COG4585	Histidine kinase
MLA2C4_05385	COG2197	response regulator
MLA2C4_05415	COG0420	3'-5' exonuclease activity
MLA2C4_05420	COG4717	serine-type aminopeptidase activity
MLA2C4_05450	COG0346	lactoylglutathione lyase activity
MLA2C4_05455	COG0346	lactoylglutathione lyase activity
MLA2C4_05460	COG0457	Tetratricopeptide repeat
MLA2C4_05470	COG2267	carboxylic ester hydrolase activity
MLA2C4_05500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLA2C4_05505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MLA2C4_05515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLA2C4_05525	COG1595	DNA-templated transcription, initiation
MLA2C4_05535	COG0772	Belongs to the SEDS family
MLA2C4_05545	COG3973	AAA domain
MLA2C4_05555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MLA2C4_05580	COG0537	adenosine 5'-monophosphoramidase activity
MLA2C4_05585	COG1131	(ABC) transporter
MLA2C4_05590	COG4473	ABC transporter
MLA2C4_05650	COG1309	transcriptional regulator
MLA2C4_05655	COG3402	PFAM membrane-flanked domain
MLA2C4_05660	COG3428	Bacterial PH domain
MLA2C4_05685	COG3402	PFAM membrane-flanked domain
MLA2C4_05690	COG3428	Bacterial PH domain
MLA2C4_05695	COG2329	Antibiotic biosynthesis monooxygenase
MLA2C4_05700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MLA2C4_05750	COG1309	transcriptional regulator
MLA2C4_05755	COG1511	domain protein
MLA2C4_05770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_05780	COG2378	regulation of single-species biofilm formation
MLA2C4_05785	COG1609	Transcriptional regulator
MLA2C4_05795	COG1234	tRNA 3'-trailer cleavage
MLA2C4_05800	COG0095	Lipoate-protein ligase
MLA2C4_05810	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_05830	COG1073	alpha beta
MLA2C4_05835	COG1408	metallophosphoesterase
MLA2C4_05840	COG1078	dGTPase activity
MLA2C4_05845	COG1733	regulation of RNA biosynthetic process
MLA2C4_05850	COG0477	Major facilitator Superfamily
MLA2C4_05860	COG1595	DNA-templated transcription, initiation
MLA2C4_05870	COG2207	Transcriptional regulator
MLA2C4_05870	COG3708	Transcriptional regulator
MLA2C4_05875	COG2205	protein histidine kinase activity
MLA2C4_05880	COG0745	RESPONSE REGULATOR receiver
MLA2C4_05905	COG0501	Belongs to the peptidase M48B family
MLA2C4_05910	COG0840	transmembrane signaling receptor activity
MLA2C4_05915	COG0697	spore germination
MLA2C4_05930	COG0497	DNA recombination
MLA2C4_05935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MLA2C4_05940	COG2224	Isocitrate lyase
MLA2C4_05950	COG1278	Cold shock
MLA2C4_05980	COG0398	Pfam SNARE associated Golgi protein
MLA2C4_06040	COG0179	Fumarylacetoacetate (FAA) hydrolase
MLA2C4_06065	COG0367	asparagine synthase
MLA2C4_06075	COG0753	catalase activity
MLA2C4_06085	COG0004	ammonium transporteR
MLA2C4_06115	COG2996	Protein conserved in bacteria
MLA2C4_06120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MLA2C4_06130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_06145	COG0561	phosphatase activity
MLA2C4_06165	COG2267	carboxylic ester hydrolase activity
MLA2C4_06180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLA2C4_06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MLA2C4_06190	COG5504	Zn-dependent protease
MLA2C4_06200	COG0180	Tryptophanyl-tRNA synthetase
MLA2C4_06215	COG4166	transmembrane transport
MLA2C4_06220	COG0601	transmembrane transport
MLA2C4_06225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLA2C4_06230	COG0444	Belongs to the ABC transporter superfamily
MLA2C4_06235	COG4608	Belongs to the ABC transporter superfamily
MLA2C4_06240	COG0534	Mate efflux family protein
MLA2C4_06245	COG4166	transmembrane transport
MLA2C4_06255	COG1393	Belongs to the ArsC family
MLA2C4_06260	COG0861	Integral membrane protein TerC family
MLA2C4_06270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLA2C4_06280	COG1164	Oligoendopeptidase f
MLA2C4_06290	COG2346	COG2346, Truncated hemoglobins
MLA2C4_06295	COG4116	CYTH
MLA2C4_06305	COG2357	RelA SpoT domain protein
MLA2C4_06315	COG0564	pseudouridine synthase activity
MLA2C4_06330	COG0772	Belongs to the SEDS family
MLA2C4_06335	COG1216	Glycosyl transferase, family 2
MLA2C4_06355	COG0457	Tetratricopeptide repeat
MLA2C4_06355	COG0463	Glycosyl transferase, family 2
MLA2C4_06375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLA2C4_06390	COG1091	dTDP-4-dehydrorhamnose reductase activity
MLA2C4_06435	COG2153	protein acetylation
MLA2C4_06445	COG2382	esterase
MLA2C4_06475	COG5492	domain, Protein
MLA2C4_06480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLA2C4_06495	COG0512	Glutamine amidotransferase of anthranilate synthase
MLA2C4_06495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLA2C4_06530	COG1620	l-lactate permease
MLA2C4_06535	COG5634	Uncharacterized conserved protein (DUF2278)
MLA2C4_06570	COG2226	methyltransferase
MLA2C4_06590	COG0508	dehydrogenase complex catalyzes the overall conversion of
MLA2C4_06600	COG1476	TRANSCRIPTIONal
MLA2C4_06710	COG2003	Belongs to the UPF0758 family
MLA2C4_06740	COG0582	viral genome integration into host DNA
MLA2C4_06745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MLA2C4_06795	COG1686	Belongs to the peptidase S11 family
MLA2C4_06800	COG0681	Belongs to the peptidase S26 family
MLA2C4_06835	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_06845	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLA2C4_06850	COG1177	transmembrane transport
MLA2C4_06855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MLA2C4_06860	COG0671	phosphoesterase, PA-phosphatase related
MLA2C4_06865	COG2409	Drug exporters of the RND superfamily
MLA2C4_06875	COG0564	pseudouridine synthase activity
MLA2C4_06885	COG2340	Cysteine-rich secretory protein family
MLA2C4_06890	COG0247	lactate metabolic process
MLA2C4_06895	COG0277	FAD linked oxidase domain protein
MLA2C4_06900	COG3835	regulator
MLA2C4_06910	COG0745	RESPONSE REGULATOR receiver
MLA2C4_06915	COG5002	protein histidine kinase activity
MLA2C4_06920	COG2186	Transcriptional regulator
MLA2C4_06940	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MLA2C4_06950	COG2116	formate transmembrane transporter activity
MLA2C4_06955	COG0861	Integral membrane protein TerC family
MLA2C4_06970	COG2030	dehydratase
MLA2C4_06990	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_06995	COG3243	poly(R)-hydroxyalkanoic acid synthase
MLA2C4_07005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MLA2C4_07020	COG1840	ABC-type Fe3 transport system, periplasmic component
MLA2C4_07025	COG3842	ATPase activity
MLA2C4_07050	COG1349	DNA-binding transcription factor activity
MLA2C4_07060	COG0235	Class ii aldolase
MLA2C4_07070	COG2861	carbohydrate metabolic process
MLA2C4_07080	COG3852	Histidine kinase
MLA2C4_07085	COG1846	Transcriptional regulator
MLA2C4_07095	COG2318	DinB family
MLA2C4_07105	COG5002	protein histidine kinase activity
MLA2C4_07115	COG0720	synthase
MLA2C4_07130	COG4873	Protein conserved in bacteria
MLA2C4_07165	COG1780	Probably involved in ribonucleotide reductase function
MLA2C4_07180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLA2C4_07185	COG1725	Transcriptional regulator
MLA2C4_07190	COG1131	(ABC) transporter
MLA2C4_07200	COG1131	(ABC) transporter
MLA2C4_07205	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MLA2C4_07210	COG1266	CAAX protease self-immunity
MLA2C4_07220	COG1522	sequence-specific DNA binding
MLA2C4_07230	COG1335	isochorismatase
MLA2C4_07240	COG1619	proteins homologs of microcin C7 resistance protein MccF
MLA2C4_07255	COG2070	2-Nitropropane dioxygenase
MLA2C4_07260	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLA2C4_07270	COG1696	Membrane protein involved in D-alanine export
MLA2C4_07290	COG0716	FMN binding
MLA2C4_07320	COG1968	undecaprenyl-diphosphatase activity
MLA2C4_07335	COG1846	Transcriptional regulator
MLA2C4_07345	COG1301	dicarboxylic acid transport
MLA2C4_07350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MLA2C4_07355	COG4709	membrane
MLA2C4_07360	COG3874	Sporulation protein YtfJ
MLA2C4_07385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLA2C4_07390	COG0028	Belongs to the TPP enzyme family
MLA2C4_07395	COG0440	acetolactate synthase activity
MLA2C4_07470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MLA2C4_07485	COG1183	phosphatidylcholine synthase activity
MLA2C4_07490	COG1368	sulfuric ester hydrolase activity
MLA2C4_07500	COG0019	diaminopimelate decarboxylase activity
MLA2C4_07520	COG0529	Catalyzes the synthesis of activated sulfate
MLA2C4_07525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLA2C4_07545	COG1648	precorrin-2 dehydrogenase activity
MLA2C4_07555	COG0733	neurotransmitter:sodium symporter activity
MLA2C4_07575	COG1757	Na H antiporter
MLA2C4_07590	COG4758	membrane
MLA2C4_07595	COG4585	Histidine kinase
MLA2C4_07600	COG2197	response regulator
MLA2C4_07610	COG1114	Component of the transport system for branched-chain amino acids
MLA2C4_07620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MLA2C4_07660	COG0730	response to heat
MLA2C4_07665	COG0306	phosphate transporter
MLA2C4_07670	COG1392	Phosphate transport regulator
MLA2C4_07675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MLA2C4_07690	COG3852	Histidine kinase
MLA2C4_07695	COG1801	Protein of unknown function DUF72
MLA2C4_07705	COG0582	viral genome integration into host DNA
MLA2C4_07710	COG5002	protein histidine kinase activity
MLA2C4_07725	COG0392	lysyltransferase activity
MLA2C4_07725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLA2C4_07740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLA2C4_07745	COG1686	Belongs to the peptidase S11 family
MLA2C4_07750	COG2715	membrane protein required for spore maturation
MLA2C4_07755	COG0700	Nucleoside recognition
MLA2C4_07760	COG1187	pseudouridine synthase activity
MLA2C4_07770	COG1333	cytochrome c biogenesis protein
MLA2C4_07775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MLA2C4_07780	COG0745	RESPONSE REGULATOR receiver
MLA2C4_07785	COG5002	protein histidine kinase activity
MLA2C4_07790	COG2096	Adenosyltransferase
MLA2C4_07795	COG1388	LysM domain
MLA2C4_07805	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLA2C4_07810	COG1141	Ferredoxin
MLA2C4_07820	COG0514	ATP-dependent DNA helicase (RecQ)
MLA2C4_07825	COG1266	CAAX protease self-immunity
MLA2C4_07835	COG1408	metallophosphoesterase
MLA2C4_07845	COG4862	establishment of competence for transformation
MLA2C4_07850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MLA2C4_07870	COG0492	ferredoxin-NADP+ reductase activity
MLA2C4_07875	COG0252	asparaginase activity
MLA2C4_07940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLA2C4_07955	COG0142	geranyltranstransferase activity
MLA2C4_07965	COG0142	geranyltranstransferase activity
MLA2C4_07990	COG0457	Tetratricopeptide repeat
MLA2C4_08010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MLA2C4_08015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MLA2C4_08015	COG2010	Cytochrome c
MLA2C4_08020	COG4347	Protein of unknown function (DUF1405)
MLA2C4_08035	COG2738	Putative neutral zinc metallopeptidase
MLA2C4_08045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_08055	COG1694	Mazg nucleotide pyrophosphohydrolase
MLA2C4_08070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MLA2C4_08075	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_08110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MLA2C4_08110	COG1199	ATP-dependent helicase activity
MLA2C4_08130	COG3935	DnaD domain protein
MLA2C4_08135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLA2C4_08145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MLA2C4_08145	COG4499	WXG100 protein secretion system (Wss), protein YukC
MLA2C4_08200	COG0116	Belongs to the methyltransferase superfamily
MLA2C4_08210	COG1199	ATP-dependent helicase activity
MLA2C4_08215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLA2C4_08225	COG0024	Methionine aminopeptidase
MLA2C4_08235	COG2233	PERMEase
MLA2C4_08240	COG2311	Membrane
MLA2C4_08245	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLA2C4_08255	COG0456	acetyltransferase
MLA2C4_08290	COG0754	glutathionylspermidine amidase activity
MLA2C4_08305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLA2C4_08340	COG0328	RNA-DNA hybrid ribonuclease activity
MLA2C4_08375	COG3403	YqcI/YcgG family
MLA2C4_08380	COG1280	lysine exporter protein (LysE YggA)
MLA2C4_08395	COG3162	membrane
MLA2C4_08400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLA2C4_08405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLA2C4_08415	COG0475	glutathione-regulated potassium exporter activity
MLA2C4_08420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLA2C4_08425	COG4978	Transcriptional regulator
MLA2C4_08425	COG0789	Transcriptional regulator
MLA2C4_08435	COG2323	membrane
MLA2C4_08440	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MLA2C4_08485	COG2814	Major facilitator Superfamily
MLA2C4_08505	COG1923	regulation of RNA biosynthetic process
MLA2C4_08515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MLA2C4_08520	COG1360	Flagellar Motor Protein
MLA2C4_08525	COG2201	protein-glutamate methylesterase activity
MLA2C4_08530	COG0643	Histidine kinase
MLA2C4_08530	COG2198	Histidine kinase
MLA2C4_08535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLA2C4_08535	COG1776	CheC inhibitor of MCP methylation
MLA2C4_08550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MLA2C4_08570	COG1256	bacterial-type flagellum assembly
MLA2C4_08575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLA2C4_08580	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLA2C4_08595	COG1815	bacterial-type flagellum-dependent cell motility
MLA2C4_08600	COG1558	bacterial-type flagellum-dependent cell motility
MLA2C4_08605	COG1677	Flagellar hook-basal body complex protein FliE
MLA2C4_08610	COG1766	The M ring may be actively involved in energy transduction
MLA2C4_08615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLA2C4_08625	COG1157	protein secretion by the type III secretion system
MLA2C4_08645	COG1749	Flagellar hook protein flgE
MLA2C4_08660	COG0784	Response regulator, receiver
MLA2C4_08660	COG0835	chemotaxis
MLA2C4_08670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLA2C4_08675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLA2C4_08675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLA2C4_08680	COG0741	lytic transglycosylase activity
MLA2C4_08690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLA2C4_08695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLA2C4_08695	COG1776	CheC inhibitor of MCP methylation
MLA2C4_08705	COG1338	Plays a role in the flagellum-specific transport system
MLA2C4_08710	COG1987	bacterial-type flagellum assembly
MLA2C4_08720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLA2C4_08725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLA2C4_08730	COG1419	protein localization to endoplasmic reticulum
MLA2C4_08735	COG4786	Flagellar basal body rod
MLA2C4_08785	COG2329	Antibiotic biosynthesis monooxygenase
MLA2C4_08805	COG3764	Sortase (surface protein transpeptidase)
MLA2C4_08810	COG3764	Sortase (surface protein transpeptidase)
MLA2C4_08840	COG3842	ATPase activity
MLA2C4_08845	COG0725	ABC transporter, periplasmic molybdate-binding protein
MLA2C4_08850	COG1177	transmembrane transport
MLA2C4_08925	COG0367	asparagine synthase
MLA2C4_08955	COG1802	Transcriptional regulator
MLA2C4_08960	COG0697	spore germination
MLA2C4_08965	COG1216	Glycosyl transferase, family 2
MLA2C4_08965	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_08970	COG1757	Na H antiporter
MLA2C4_08975	COG0114	fumarate hydratase activity
MLA2C4_08990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_09000	COG0534	Mate efflux family protein
MLA2C4_09005	COG3340	Belongs to the peptidase S51 family
MLA2C4_09025	COG0785	Cytochrome C biogenesis protein
MLA2C4_09050	COG2733	membrane
MLA2C4_09090	COG1131	(ABC) transporter
MLA2C4_09110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLA2C4_09135	COG0528	UMP kinase activity
MLA2C4_09145	COG1027	Aspartate ammonia-lyase
MLA2C4_09150	COG0281	malic enzyme
MLA2C4_09155	COG4191	Histidine kinase
MLA2C4_09160	COG0784	Response regulator, receiver
MLA2C4_09165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MLA2C4_09225	COG1051	belongs to the nudix hydrolase family
MLA2C4_09230	COG0860	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_09255	COG3842	ATPase activity
MLA2C4_09260	COG2508	Transcriptional regulator
MLA2C4_09270	COG1175	transmembrane transport
MLA2C4_09275	COG0395	ABC-type sugar transport system, permease component
MLA2C4_09290	COG2222	sugar isomerase
MLA2C4_09305	COG1105	Belongs to the carbohydrate kinase PfkB family
MLA2C4_09310	COG1940	carbohydrate kinase activity
MLA2C4_09325	COG0477	Major facilitator Superfamily
MLA2C4_09330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLA2C4_09340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLA2C4_09345	COG4166	transmembrane transport
MLA2C4_09350	COG2223	nitrite transmembrane transporter activity
MLA2C4_09355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MLA2C4_09370	COG2244	polysaccharide biosynthetic process
MLA2C4_09375	COG0733	neurotransmitter:sodium symporter activity
MLA2C4_09390	COG2323	membrane
MLA2C4_09410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLA2C4_09415	COG2132	Multicopper oxidase
MLA2C4_09425	COG5002	protein histidine kinase activity
MLA2C4_09430	COG0745	RESPONSE REGULATOR receiver
MLA2C4_09440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLA2C4_09445	COG0028	Belongs to the TPP enzyme family
MLA2C4_09465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLA2C4_09490	COG2814	Major facilitator Superfamily
MLA2C4_09495	COG3384	dioxygenase
MLA2C4_09510	COG3279	Response regulator of the LytR AlgR family
MLA2C4_09515	COG0427	acetyl-CoA hydrolase
MLA2C4_09535	COG1073	alpha beta
MLA2C4_09545	COG4166	transmembrane transport
MLA2C4_09550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_09570	COG1914	H( )-stimulated, divalent metal cation uptake system
MLA2C4_09585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLA2C4_09590	COG0531	amino acid
MLA2C4_09615	COG2390	Transcriptional regulator
MLA2C4_09625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_09630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MLA2C4_09645	COG4846	Membrane protein involved in cytochrome C biogenesis
MLA2C4_09655	COG0006	proline dipeptidase activity
MLA2C4_09660	COG2132	Multicopper oxidase
MLA2C4_09700	COG1114	Component of the transport system for branched-chain amino acids
MLA2C4_09710	COG4641	Protein conserved in bacteria
MLA2C4_09720	COG1276	copper resistance
MLA2C4_09720	COG2372	response to copper ion
MLA2C4_09725	COG4549	nuclear export factor GLE1
MLA2C4_09730	COG0697	spore germination
MLA2C4_09735	COG0583	DNA-binding transcription factor activity
MLA2C4_09740	COG1959	2 iron, 2 sulfur cluster binding
MLA2C4_09745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MLA2C4_09750	COG0778	Nitroreductase
MLA2C4_09765	COG0628	permease
MLA2C4_09775	COG1231	oxidoreductase activity
MLA2C4_09780	COG0523	cobalamin synthesis protein
MLA2C4_09790	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_09795	COG2030	dehydratase
MLA2C4_09800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLA2C4_09815	COG0411	ABC transporter
MLA2C4_09825	COG0559	Belongs to the binding-protein-dependent transport system permease family
MLA2C4_09835	COG0583	DNA-binding transcription factor activity
MLA2C4_09845	COG1942	4-Oxalocrotonate Tautomerase
MLA2C4_09865	COG1271	oxidase subunit
MLA2C4_09870	COG1294	oxidase, subunit
MLA2C4_09875	COG4988	ABC transporter
MLA2C4_09880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MLA2C4_09885	COG1216	Glycosyl transferase, family 2
MLA2C4_09900	COG1619	proteins homologs of microcin C7 resistance protein MccF
MLA2C4_09905	COG1686	Belongs to the peptidase S11 family
MLA2C4_09920	COG1388	LysM domain
MLA2C4_09920	COG0791	NLP P60 protein
MLA2C4_09930	COG1132	(ABC) transporter
MLA2C4_09935	COG0745	RESPONSE REGULATOR receiver
MLA2C4_09940	COG5002	protein histidine kinase activity
MLA2C4_09945	COG2205	protein histidine kinase activity
MLA2C4_09950	COG0745	RESPONSE REGULATOR receiver
MLA2C4_09975	COG0300	oxidoreductase activity
MLA2C4_09990	COG0726	polysaccharide deacetylase
MLA2C4_10000	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MLA2C4_10010	COG0460	homoserine dehydrogenase
MLA2C4_10035	COG1316	TRANSCRIPTIONal
MLA2C4_10045	COG0745	RESPONSE REGULATOR receiver
MLA2C4_10050	COG5002	protein histidine kinase activity
MLA2C4_10055	COG0726	polysaccharide deacetylase
MLA2C4_10065	COG1285	pathogenesis
MLA2C4_10070	COG1247	-acetyltransferase
MLA2C4_10080	COG4264	IucA IucC family
MLA2C4_10085	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_10105	COG1082	Xylose isomerase domain protein TIM barrel
MLA2C4_10115	COG2814	Major facilitator Superfamily
MLA2C4_10120	COG1279	arginine transmembrane transporter activity
MLA2C4_10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_10135	COG1752	Esterase of the alpha-beta hydrolase superfamily
MLA2C4_10170	COG0577	efflux transmembrane transporter activity
MLA2C4_10175	COG2002	toxin-antitoxin pair type II binding
MLA2C4_10180	COG1404	Belongs to the peptidase S8 family
MLA2C4_10185	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MLA2C4_10190	COG0640	Transcriptional regulator
MLA2C4_10195	COG0667	Aldo Keto reductase
MLA2C4_10200	COG2814	Major facilitator Superfamily
MLA2C4_10230	COG0840	transmembrane signaling receptor activity
MLA2C4_10245	COG3949	Membrane
MLA2C4_10250	COG0783	Belongs to the Dps family
MLA2C4_10265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLA2C4_10280	COG1231	oxidoreductase activity
MLA2C4_10285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_10290	COG4989	oxidoreductase activity
MLA2C4_10295	COG0523	cobalamin synthesis protein
MLA2C4_10300	COG0456	acetyltransferase
MLA2C4_10305	COG0803	Belongs to the bacterial solute-binding protein 9 family
MLA2C4_10305	COG3443	Belongs to the bacterial solute-binding protein 9 family
MLA2C4_10310	COG0702	epimerase
MLA2C4_10320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLA2C4_10330	COG4166	transmembrane transport
MLA2C4_10345	COG0406	alpha-ribazole phosphatase activity
MLA2C4_10355	COG5337	Spore coat protein CotH
MLA2C4_10360	COG1051	belongs to the nudix hydrolase family
MLA2C4_10365	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_10370	COG2244	polysaccharide biosynthetic process
MLA2C4_10380	COG0701	Predicted permease
MLA2C4_10385	COG3689	TIGRFAM TIGR03943 family protein
MLA2C4_10390	COG1607	acyl-coa hydrolase
MLA2C4_10420	COG0702	epimerase
MLA2C4_10425	COG2839	Protein conserved in bacteria
MLA2C4_10430	COG1253	flavin adenine dinucleotide binding
MLA2C4_10445	COG1114	Component of the transport system for branched-chain amino acids
MLA2C4_10450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLA2C4_10470	COG0860	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_10480	COG1876	peptidase activity
MLA2C4_10485	COG0494	nUDIX hydrolase
MLA2C4_10495	COG0154	amidase activity
MLA2C4_10500	COG2211	Major facilitator Superfamily
MLA2C4_10555	COG0561	phosphatase activity
MLA2C4_10565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLA2C4_10585	COG1819	glycosyl
MLA2C4_10590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_10595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_10615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_10625	COG0456	acetyltransferase
MLA2C4_10690	COG3874	Sporulation protein YtfJ
MLA2C4_10715	COG2226	methyltransferase
MLA2C4_10735	COG1082	Xylose isomerase domain protein TIM barrel
MLA2C4_10740	COG0346	lactoylglutathione lyase activity
MLA2C4_10750	COG0604	alcohol dehydrogenase
MLA2C4_10755	COG1595	DNA-templated transcription, initiation
MLA2C4_10780	COG0426	domain, Protein
MLA2C4_10780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLA2C4_10790	COG0386	Belongs to the glutathione peroxidase family
MLA2C4_10795	COG1305	Transglutaminase-like
MLA2C4_10800	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MLA2C4_10805	COG0714	Associated with various cellular activities
MLA2C4_10810	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MLA2C4_10845	COG2359	stage V sporulation protein S
MLA2C4_10855	COG2856	Zn peptidase
MLA2C4_10865	COG0582	viral genome integration into host DNA
MLA2C4_10925	COG0457	Tetratricopeptide repeat
MLA2C4_10940	COG1418	mRNA catabolic process
MLA2C4_10945	COG0488	(ABC) transporter
MLA2C4_10960	COG0629	single-stranded DNA binding
MLA2C4_10965	COG1413	lyase activity
MLA2C4_10980	COG2136	Putative SAM-dependent methyltransferase
MLA2C4_10980	COG2521	methyltransferase
MLA2C4_10985	COG0018	arginyl-trna synthetase
MLA2C4_11015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MLA2C4_11020	COG0017	Asparaginyl-tRNA synthetase
MLA2C4_11040	COG1674	ftsk spoiiie
MLA2C4_11090	COG0733	neurotransmitter:sodium symporter activity
MLA2C4_11110	COG2610	gluconate transmembrane transporter activity
MLA2C4_11115	COG1454	alcohol dehydrogenase
MLA2C4_11120	COG1794	racemase activity, acting on amino acids and derivatives
MLA2C4_11130	COG0456	acetyltransferase
MLA2C4_11135	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MLA2C4_11145	COG1131	(ABC) transporter
MLA2C4_11150	COG4473	ABC transporter
MLA2C4_11160	COG0546	phosphoglycolate phosphatase activity
MLA2C4_11185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MLA2C4_11205	COG0768	penicillin binding
MLA2C4_11215	COG0204	Acyl-transferase
MLA2C4_11220	COG1272	protein, Hemolysin III
MLA2C4_11230	COG0805	protein transport
MLA2C4_11240	COG1307	EDD domain protein, DegV family
MLA2C4_11250	COG1999	signal sequence binding
MLA2C4_11255	COG0071	Belongs to the small heat shock protein (HSP20) family
MLA2C4_11260	COG0367	asparagine synthase
MLA2C4_11280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_11285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLA2C4_11305	COG1335	isochorismatase
MLA2C4_11310	COG0668	transmembrane transport
MLA2C4_11315	COG4585	Histidine kinase
MLA2C4_11315	COG2203	Gaf domain
MLA2C4_11320	COG2197	response regulator
MLA2C4_11325	COG1737	Transcriptional regulator
MLA2C4_11330	COG1064	alcohol dehydrogenase
MLA2C4_11350	COG1522	sequence-specific DNA binding
MLA2C4_11355	COG1070	Carbohydrate kinase
MLA2C4_11365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MLA2C4_11400	COG0517	IMP dehydrogenase activity
MLA2C4_11400	COG1125	glycine betaine transport
MLA2C4_11405	COG1174	glycine betaine transport
MLA2C4_11440	COG1253	flavin adenine dinucleotide binding
MLA2C4_11445	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_11450	COG5506	Protein of unknown function (DUF1694)
MLA2C4_11465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLA2C4_11470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLA2C4_11475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MLA2C4_11480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MLA2C4_11485	COG0456	acetyltransferase
MLA2C4_11490	COG3829	transcription factor binding
MLA2C4_11495	COG1509	lysine 2,3-aminomutase activity
MLA2C4_11530	COG0515	serine threonine protein kinase
MLA2C4_11530	COG3064	Membrane
MLA2C4_11530	COG4991	sh3 domain protein
MLA2C4_11535	COG4326	sporulation control protein
MLA2C4_11540	COG0671	phosphoesterase, PA-phosphatase related
MLA2C4_11545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLA2C4_11550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MLA2C4_11555	COG0582	viral genome integration into host DNA
MLA2C4_11580	COG1396	sequence-specific DNA binding
MLA2C4_11650	COG5582	Belongs to the UPF0302 family
MLA2C4_11655	COG2002	toxin-antitoxin pair type II binding
MLA2C4_11770	COG3728	DNA packaging
MLA2C4_11770	COG5484	DNA packaging
MLA2C4_11775	COG1783	phage Terminase large subunit
MLA2C4_11925	COG1715	Restriction endonuclease
MLA2C4_11925	COG1787	Restriction endonuclease
MLA2C4_12030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MLA2C4_12070	COG0300	oxidoreductase activity
MLA2C4_12090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MLA2C4_12090	COG4499	WXG100 protein secretion system (Wss), protein YukC
MLA2C4_12100	COG2814	Major facilitator Superfamily
MLA2C4_12110	COG0372	Belongs to the citrate synthase family
MLA2C4_12115	COG2079	MmgE PrpD family protein
MLA2C4_12120	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLA2C4_12125	COG1960	acyl-CoA dehydrogenase activity
MLA2C4_12130	COG2084	Dehydrogenase
MLA2C4_12135	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_12140	COG1280	lysine exporter protein (LysE YggA)
MLA2C4_12145	COG1024	Enoyl-CoA hydratase
MLA2C4_12160	COG0420	3'-5' exonuclease activity
MLA2C4_12185	COG2223	nitrite transmembrane transporter activity
MLA2C4_12190	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_12195	COG1169	isochorismate synthase
MLA2C4_12200	COG1021	2,3-dihydroxybenzoate-AMP ligase
MLA2C4_12205	COG3433	isochorismatase activity
MLA2C4_12205	COG1535	isochorismatase
MLA2C4_12210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MLA2C4_12215	COG3251	PFAM MbtH domain protein
MLA2C4_12220	COG2814	Major facilitator Superfamily
MLA2C4_12235	COG0776	regulation of translation
MLA2C4_12245	COG2318	DinB family
MLA2C4_12250	COG1115	amino acid carrier protein
MLA2C4_12265	COG2329	Antibiotic biosynthesis monooxygenase
MLA2C4_12270	COG1187	pseudouridine synthase activity
MLA2C4_12275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLA2C4_12280	COG1136	(ABC) transporter
MLA2C4_12290	COG0596	Alpha beta hydrolase
MLA2C4_12295	COG2814	Major facilitator Superfamily
MLA2C4_12320	COG0028	Belongs to the TPP enzyme family
MLA2C4_12330	COG2226	methyltransferase
MLA2C4_12360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MLA2C4_12375	COG1846	Transcriptional regulator
MLA2C4_12410	COG1247	-acetyltransferase
MLA2C4_12450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_12460	COG1278	Cold shock
MLA2C4_12475	COG0010	Belongs to the arginase family
MLA2C4_12485	COG0583	DNA-binding transcription factor activity
MLA2C4_12490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLA2C4_12505	COG0583	DNA-binding transcription factor activity
MLA2C4_12510	COG2258	MOSC domain
MLA2C4_12520	COG1132	(ABC) transporter
MLA2C4_12525	COG1132	(ABC) transporter
MLA2C4_12565	COG1396	sequence-specific DNA binding
MLA2C4_12600	COG4824	toxin secretion phage lysis holin
MLA2C4_12655	COG1476	TRANSCRIPTIONal
MLA2C4_12715	COG1233	COG1233 Phytoene dehydrogenase and related
MLA2C4_12720	COG1595	DNA-templated transcription, initiation
MLA2C4_12740	COG1649	PFAM Uncharacterised BCR, COG1649
MLA2C4_12765	COG2971	BadF BadG BcrA BcrD
MLA2C4_12785	COG1846	Transcriptional regulator
MLA2C4_12875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLA2C4_12875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLA2C4_12940	COG2002	toxin-antitoxin pair type II binding
MLA2C4_12955	COG0515	serine threonine protein kinase
MLA2C4_12955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MLA2C4_12970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MLA2C4_13100	COG5632	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_13115	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_13185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_13230	COG1309	transcriptional regulator
MLA2C4_13245	COG1136	(ABC) transporter
MLA2C4_13245	COG0577	efflux transmembrane transporter activity
MLA2C4_13250	COG0500	methyltransferase
MLA2C4_13250	COG3615	Tellurite resistance protein tehB
MLA2C4_13260	COG3961	Belongs to the TPP enzyme family
MLA2C4_13265	COG1846	Transcriptional regulator
MLA2C4_13295	COG2195	Cleaves the N-terminal amino acid of tripeptides
MLA2C4_13315	COG1686	Belongs to the peptidase S11 family
MLA2C4_13330	COG0768	penicillin binding
MLA2C4_13335	COG1595	DNA-templated transcription, initiation
MLA2C4_13345	COG0768	penicillin binding
MLA2C4_13360	COG1609	Transcriptional regulator
MLA2C4_13365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MLA2C4_13370	COG0561	phosphatase activity
MLA2C4_13375	COG0673	inositol 2-dehydrogenase activity
MLA2C4_13380	COG0738	Major facilitator superfamily
MLA2C4_13415	COG1252	NADH dehydrogenase
MLA2C4_13435	COG1131	(ABC) transporter
MLA2C4_13445	COG1309	transcriptional regulator
MLA2C4_13460	COG1960	acyl-CoA dehydrogenase activity
MLA2C4_13465	COG0439	Biotin carboxylase
MLA2C4_13470	COG0511	ligase activity, forming carbon-carbon bonds
MLA2C4_13475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLA2C4_13480	COG1024	Enoyl-CoA hydratase
MLA2C4_13485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MLA2C4_13490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MLA2C4_13505	COG0572	uridine kinase
MLA2C4_13515	COG2318	DinB family
MLA2C4_13520	COG1686	Belongs to the peptidase S11 family
MLA2C4_13545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLA2C4_13565	COG3227	Zinc metalloprotease (Elastase)
MLA2C4_13570	COG2207	Transcriptional regulator
MLA2C4_13615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MLA2C4_13650	COG0693	protein deglycase activity
MLA2C4_13665	COG2814	Major facilitator Superfamily
MLA2C4_13670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MLA2C4_13680	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_13685	COG1733	regulation of RNA biosynthetic process
MLA2C4_13735	COG0697	spore germination
MLA2C4_13740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_13760	COG1063	alcohol dehydrogenase
MLA2C4_13765	COG2323	membrane
MLA2C4_13775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLA2C4_13795	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MLA2C4_13800	COG3773	Cell wall hydrolase
MLA2C4_13810	COG0745	RESPONSE REGULATOR receiver
MLA2C4_13815	COG2205	protein histidine kinase activity
MLA2C4_13825	COG0583	DNA-binding transcription factor activity
MLA2C4_13830	COG0667	Aldo Keto reductase
MLA2C4_13850	COG1136	(ABC) transporter
MLA2C4_13855	COG0577	efflux transmembrane transporter activity
MLA2C4_13875	COG0460	homoserine dehydrogenase
MLA2C4_13880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_13890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLA2C4_13940	COG4824	toxin secretion phage lysis holin
MLA2C4_14020	COG2124	cytochrome p450
MLA2C4_14060	COG0675	Transposase, IS605 OrfB family
MLA2C4_14070	COG0561	phosphatase activity
MLA2C4_14075	COG5002	protein histidine kinase activity
MLA2C4_14085	COG1819	glycosyl
MLA2C4_14090	COG1794	racemase activity, acting on amino acids and derivatives
MLA2C4_14115	COG2205	protein histidine kinase activity
MLA2C4_14125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLA2C4_14130	COG0604	alcohol dehydrogenase
MLA2C4_14135	COG0671	phosphoesterase, PA-phosphatase related
MLA2C4_14180	COG0789	Transcriptional regulator
MLA2C4_14185	COG2814	Major facilitator Superfamily
MLA2C4_14190	COG0789	Transcriptional regulator
MLA2C4_14190	COG4978	Transcriptional regulator
MLA2C4_14225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_14230	COG0697	spore germination
MLA2C4_14260	COG2223	nitrite transmembrane transporter activity
MLA2C4_14280	COG2816	NAD+ diphosphatase activity
MLA2C4_14285	COG0592	DNA-directed DNA polymerase activity
MLA2C4_14290	COG1051	belongs to the nudix hydrolase family
MLA2C4_14310	COG3878	Protein conserved in bacteria
MLA2C4_14330	COG4667	esterase of the alpha-beta hydrolase superfamily
MLA2C4_14370	COG0322	excinuclease ABC activity
MLA2C4_14405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLA2C4_14435	COG0745	RESPONSE REGULATOR receiver
MLA2C4_14440	COG5002	protein histidine kinase activity
MLA2C4_14470	COG1136	(ABC) transporter
MLA2C4_14475	COG0577	efflux transmembrane transporter activity
MLA2C4_14490	COG1523	belongs to the glycosyl hydrolase 13 family
MLA2C4_14495	COG3227	Zinc metalloprotease (Elastase)
MLA2C4_14515	COG0201	protein transport
MLA2C4_14525	COG0697	spore germination
MLA2C4_14530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_14535	COG0604	alcohol dehydrogenase
MLA2C4_14570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_14585	COG2959	enzyme of heme biosynthesis
MLA2C4_14590	COG3773	Cell wall hydrolase
MLA2C4_14590	COG3409	Peptidoglycan-binding domain 1 protein
MLA2C4_14620	COG1309	transcriptional regulator
MLA2C4_14650	COG3284	Transcriptional regulator
MLA2C4_14660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_14665	COG1349	DNA-binding transcription factor activity
MLA2C4_14685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MLA2C4_14690	COG0508	dehydrogenase complex catalyzes the overall conversion of
MLA2C4_14695	COG0022	dehydrogenase e1 component
MLA2C4_14700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MLA2C4_14710	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_14715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLA2C4_14715	COG0456	acetyltransferase
MLA2C4_14755	COG4176	ABC-type proline glycine betaine transport system permease component
MLA2C4_14760	COG0517	IMP dehydrogenase activity
MLA2C4_14760	COG4175	Glycine betaine
MLA2C4_14770	COG0740	serine-type endopeptidase activity
MLA2C4_14790	COG2153	protein acetylation
MLA2C4_14795	COG3397	chitin binding
MLA2C4_14800	COG1819	glycosyl
MLA2C4_14815	COG2205	protein histidine kinase activity
MLA2C4_14820	COG2226	methyltransferase
MLA2C4_14825	COG2315	Protein conserved in bacteria
MLA2C4_14830	COG2333	competence protein COMEC
MLA2C4_14830	COG0658	competence protein
MLA2C4_14880	COG3973	AAA domain
MLA2C4_14890	COG2105	PFAM AIG2 family protein
MLA2C4_14895	COG0514	ATP-dependent DNA helicase (RecQ)
MLA2C4_14920	COG4637	Psort location Cytoplasmic, score
MLA2C4_14945	COG3397	chitin binding
MLA2C4_14965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLA2C4_14970	COG1115	amino acid carrier protein
MLA2C4_14975	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_14980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLA2C4_14990	COG3938	Belongs to the proline racemase family
MLA2C4_14995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLA2C4_15035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLA2C4_15040	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_15050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLA2C4_15070	COG4166	transmembrane transport
MLA2C4_15080	COG4948	Mandelate Racemase Muconate Lactonizing
MLA2C4_15130	COG2936	dipeptidyl-peptidase activity
MLA2C4_15165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLA2C4_15170	COG1164	Oligoendopeptidase f
MLA2C4_15175	COG0531	amino acid
MLA2C4_15180	COG1522	sequence-specific DNA binding
MLA2C4_15185	COG1307	EDD domain protein, DegV family
MLA2C4_15240	COG2814	Major facilitator Superfamily
MLA2C4_15250	COG1664	Polymer-forming cytoskeletal
MLA2C4_15255	COG0789	Transcriptional regulator
MLA2C4_15260	COG4533	DNA binding
MLA2C4_15265	COG2814	Major facilitator Superfamily
MLA2C4_15265	COG0477	Major facilitator Superfamily
MLA2C4_15285	COG2261	transglycosylase associated protein
MLA2C4_15300	COG2226	methyltransferase
MLA2C4_15340	COG0436	Aminotransferase
MLA2C4_15345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MLA2C4_15355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLA2C4_15370	COG1131	(ABC) transporter
MLA2C4_15415	COG0628	permease
MLA2C4_15425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLA2C4_15430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLA2C4_15435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLA2C4_15470	COG2746	aminoglycoside 3-N-acetyltransferase activity
MLA2C4_15490	COG0697	spore germination
MLA2C4_15495	COG2318	DinB family
MLA2C4_15500	COG0454	-acetyltransferase
MLA2C4_15525	COG0861	Integral membrane protein TerC family
MLA2C4_15530	COG1368	sulfuric ester hydrolase activity
MLA2C4_15535	COG0488	(ABC) transporter
MLA2C4_15540	COG2409	Drug exporters of the RND superfamily
MLA2C4_15540	COG1033	growth of symbiont in host cell
MLA2C4_15555	COG0287	Prephenate dehydrogenase
MLA2C4_15570	COG1605	Chorismate mutase
MLA2C4_15570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MLA2C4_15625	COG2610	gluconate transmembrane transporter activity
MLA2C4_15630	COG1024	Enoyl-CoA hydratase
MLA2C4_15640	COG3829	transcription factor binding
MLA2C4_15640	COG3290	protein histidine kinase activity
MLA2C4_15655	COG1879	ABC-type sugar transport system periplasmic component
MLA2C4_15660	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLA2C4_15665	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLA2C4_15675	COG2390	Transcriptional regulator
MLA2C4_15680	COG1070	Carbohydrate kinase
MLA2C4_15715	COG2329	Antibiotic biosynthesis monooxygenase
MLA2C4_15730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_15745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLA2C4_15750	COG4187	Peptidase family M20/M25/M40
MLA2C4_15755	COG1414	Transcriptional regulator
MLA2C4_15765	COG0833	amino acid
MLA2C4_15775	COG1690	Belongs to the RtcB family
MLA2C4_15780	COG3239	Fatty acid desaturase
MLA2C4_15790	COG1785	Belongs to the alkaline phosphatase family
MLA2C4_15800	COG3655	Transcriptional regulator
MLA2C4_15815	COG4377	Putative membrane peptidase family (DUF2324)
MLA2C4_15825	COG3279	Response regulator of the LytR AlgR family
MLA2C4_15840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_15845	COG0346	lactoylglutathione lyase activity
MLA2C4_15865	COG0714	Associated with various cellular activities
MLA2C4_15885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MLA2C4_15890	COG0753	catalase activity
MLA2C4_15925	COG0714	Associated with various cellular activities
MLA2C4_15940	COG0778	Nitroreductase
MLA2C4_15945	COG1846	Transcriptional regulator
MLA2C4_15985	COG1725	Transcriptional regulator
MLA2C4_16010	COG2207	Transcriptional regulator
MLA2C4_16015	COG0590	tRNA wobble adenosine to inosine editing
MLA2C4_16015	COG0037	tRNA processing
MLA2C4_16020	COG0456	acetyltransferase
MLA2C4_16040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_16065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLA2C4_16065	COG0456	acetyltransferase
MLA2C4_16090	COG0730	response to heat
MLA2C4_16100	COG0833	amino acid
MLA2C4_16110	COG4335	DNA alkylation repair
MLA2C4_16125	COG0384	phenazine biosynthesis protein PhzF
MLA2C4_16180	COG1984	allophanate hydrolase subunit 2
MLA2C4_16185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MLA2C4_16190	COG1414	Transcriptional regulator
MLA2C4_16200	COG3142	Participates in the control of copper homeostasis
MLA2C4_16205	COG0860	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_16210	COG0640	Transcriptional regulator
MLA2C4_16225	COG0156	8-amino-7-oxononanoate synthase activity
MLA2C4_16235	COG2226	methyltransferase
MLA2C4_16250	COG1960	acyl-CoA dehydrogenase activity
MLA2C4_16290	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MLA2C4_16305	COG0574	Belongs to the PEP-utilizing enzyme family
MLA2C4_16305	COG3848	Pyruvate phosphate dikinase
MLA2C4_16310	COG1819	glycosyl
MLA2C4_16315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_16335	COG1063	alcohol dehydrogenase
MLA2C4_16345	COG1027	Aspartate ammonia-lyase
MLA2C4_16350	COG0252	asparaginase activity
MLA2C4_16355	COG1396	sequence-specific DNA binding
MLA2C4_16365	COG5002	protein histidine kinase activity
MLA2C4_16390	COG2207	Transcriptional regulator
MLA2C4_16405	COG0322	excinuclease ABC activity
MLA2C4_16410	COG0531	amino acid
MLA2C4_16415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLA2C4_16425	COG0531	amino acid
MLA2C4_16430	COG0697	spore germination
MLA2C4_16440	COG0784	Response regulator, receiver
MLA2C4_16445	COG4191	Histidine kinase
MLA2C4_16450	COG2066	Belongs to the glutaminase family
MLA2C4_16460	COG1115	amino acid carrier protein
MLA2C4_16485	COG0737	Belongs to the 5'-nucleotidase family
MLA2C4_16490	COG2267	carboxylic ester hydrolase activity
MLA2C4_16495	COG1335	isochorismatase
MLA2C4_16515	COG0583	DNA-binding transcription factor activity
MLA2C4_16570	COG0598	Magnesium transport protein CorA
MLA2C4_16625	COG0415	Belongs to the DNA photolyase family
MLA2C4_16640	COG0657	acetylesterase activity
MLA2C4_16645	COG0288	reversible hydration of carbon dioxide
MLA2C4_16655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MLA2C4_16660	COG5609	conserved protein (DUF2294)
MLA2C4_16685	COG1329	Transcriptional regulator
MLA2C4_16705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLA2C4_16715	COG1575	Belongs to the MenA family. Type 1 subfamily
MLA2C4_16725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MLA2C4_16740	COG4641	Protein conserved in bacteria
MLA2C4_16765	COG0798	PFAM Bile acid sodium symporter
MLA2C4_16770	COG0346	lactoylglutathione lyase activity
MLA2C4_16775	COG0640	Transcriptional regulator
MLA2C4_16795	COG0825	malonyl-CoA metabolic process
MLA2C4_16805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLA2C4_16805	COG3320	Male sterility
MLA2C4_16825	COG0346	lactoylglutathione lyase activity
MLA2C4_16850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_16860	COG2814	Major facilitator Superfamily
MLA2C4_16870	COG4895	conserved protein (DUF2196)
MLA2C4_16915	COG0745	RESPONSE REGULATOR receiver
MLA2C4_16920	COG3850	Histidine kinase
MLA2C4_16920	COG5002	protein histidine kinase activity
MLA2C4_16950	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MLA2C4_16975	COG1476	TRANSCRIPTIONal
MLA2C4_16995	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLA2C4_17010	COG1136	(ABC) transporter
MLA2C4_17015	COG0577	efflux transmembrane transporter activity
MLA2C4_17035	COG5002	protein histidine kinase activity
MLA2C4_17035	COG3850	Histidine kinase
MLA2C4_17045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_17050	COG2271	Major facilitator Superfamily
MLA2C4_17055	COG1556	Lactate utilization protein
MLA2C4_17060	COG1139	Iron-sulfur cluster binding protein
MLA2C4_17070	COG0583	DNA-binding transcription factor activity
MLA2C4_17090	COG1619	proteins homologs of microcin C7 resistance protein MccF
MLA2C4_17110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MLA2C4_17180	COG5632	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_17180	COG3409	Peptidoglycan-binding domain 1 protein
MLA2C4_17190	COG2814	Major facilitator Superfamily
MLA2C4_17230	COG0477	Major facilitator Superfamily
MLA2C4_17245	COG1846	Transcriptional regulator
MLA2C4_17250	COG2814	Major facilitator Superfamily
MLA2C4_17260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MLA2C4_17265	COG1131	(ABC) transporter
MLA2C4_17290	COG2031	fatty acid transporter
MLA2C4_17300	COG2249	NAD(P)H dehydrogenase (quinone) activity
MLA2C4_17335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLA2C4_17355	COG1288	antiporter activity
MLA2C4_17365	COG2814	Major facilitator Superfamily
MLA2C4_17370	COG1309	transcriptional regulator
MLA2C4_17375	COG0789	Transcriptional regulator
MLA2C4_17400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLA2C4_17440	COG0583	DNA-binding transcription factor activity
MLA2C4_17460	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_17470	COG1131	(ABC) transporter
MLA2C4_17495	COG1011	Hydrolase
MLA2C4_17525	COG2816	NAD+ diphosphatase activity
MLA2C4_17530	COG0346	lactoylglutathione lyase activity
MLA2C4_17535	COG1940	carbohydrate kinase activity
MLA2C4_17550	COG0110	maltose O-acetyltransferase activity
MLA2C4_17560	COG1136	(ABC) transporter
MLA2C4_17565	COG0180	Tryptophanyl-tRNA synthetase
MLA2C4_17575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_17590	COG0628	permease
MLA2C4_17605	COG1720	tRNA m6t6A37 methyltransferase activity
MLA2C4_17610	COG0500	methyltransferase
MLA2C4_17620	COG0477	Major facilitator Superfamily
MLA2C4_17655	COG1253	flavin adenine dinucleotide binding
MLA2C4_17660	COG0789	Transcriptional regulator
MLA2C4_17670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MLA2C4_17695	COG0697	spore germination
MLA2C4_17700	COG1357	PFAM Pentapeptide repeats (8 copies)
MLA2C4_17705	COG3813	Protein conserved in bacteria
MLA2C4_17710	COG2706	6-phosphogluconolactonase activity
MLA2C4_17715	COG1070	Carbohydrate kinase
MLA2C4_17720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLA2C4_17725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MLA2C4_17730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLA2C4_17745	COG0814	amino acid
MLA2C4_17770	COG1393	Belongs to the ArsC family
MLA2C4_17780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_17815	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_17820	COG2249	NAD(P)H dehydrogenase (quinone) activity
MLA2C4_17825	COG1733	regulation of RNA biosynthetic process
MLA2C4_17840	COG1191	sigma factor activity
MLA2C4_17860	COG1266	CAAX protease self-immunity
MLA2C4_17865	COG1309	transcriptional regulator
MLA2C4_17870	COG1280	lysine exporter protein (LysE YggA)
MLA2C4_17910	COG1151	hydroxylamine reductase activity
MLA2C4_17920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_17955	COG2072	flavoprotein involved in K transport
MLA2C4_17990	COG0604	alcohol dehydrogenase
MLA2C4_17995	COG1113	amino acid transport
MLA2C4_18000	COG2814	Major facilitator Superfamily
MLA2C4_18020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MLA2C4_18025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLA2C4_18055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_18060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_18065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_18070	COG3739	integral membrane protein
MLA2C4_18090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_18105	COG0583	DNA-binding transcription factor activity
MLA2C4_18125	COG1193	negative regulation of DNA recombination
MLA2C4_18145	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MLA2C4_18150	COG1164	Oligoendopeptidase f
MLA2C4_18155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MLA2C4_18185	COG0584	glycerophosphoryl diester phosphodiesterase
MLA2C4_18195	COG0640	Transcriptional regulator
MLA2C4_18200	COG0604	alcohol dehydrogenase
MLA2C4_18210	COG0457	Tetratricopeptide repeat
MLA2C4_18220	COG2808	Putative FMN-binding domain
MLA2C4_18235	COG0385	Bile acid
MLA2C4_18240	COG0277	FAD linked oxidase domain protein
MLA2C4_18255	COG5001	Diguanylate cyclase
MLA2C4_18255	COG3300	MHYT domain
MLA2C4_18265	COG1309	transcriptional regulator
MLA2C4_18300	COG1285	pathogenesis
MLA2C4_18320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MLA2C4_18330	COG2514	catechol 2,3-dioxygenase activity
MLA2C4_18335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLA2C4_18340	COG1126	abc transporter atp-binding protein
MLA2C4_18345	COG0765	amino acid transport
MLA2C4_18350	COG2720	vancomycin resistance protein
MLA2C4_18375	COG1278	Cold shock
MLA2C4_18385	COG0716	FMN binding
MLA2C4_18395	COG0494	nUDIX hydrolase
MLA2C4_18415	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_18425	COG0165	Argininosuccinate lyase
MLA2C4_18440	COG4145	pantothenate transmembrane transporter activity
MLA2C4_18450	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_18455	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_18465	COG1657	PFAM Prenyltransferase squalene oxidase
MLA2C4_18470	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MLA2C4_18475	COG2962	Rard protein
MLA2C4_18480	COG3326	Membrane
MLA2C4_18495	COG0489	protein tyrosine kinase activity
MLA2C4_18505	COG0314	molybdopterin synthase activity
MLA2C4_18510	COG0303	'Molybdopterin
MLA2C4_18515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MLA2C4_18520	COG2116	formate transmembrane transporter activity
MLA2C4_18530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLA2C4_18535	COG5609	conserved protein (DUF2294)
MLA2C4_18540	COG2427	Protein of unknown function (DUF1641)
MLA2C4_18545	COG3383	formate dehydrogenase (NAD+) activity
MLA2C4_18585	COG2226	methyltransferase
MLA2C4_18595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MLA2C4_18600	COG4166	transmembrane transport
MLA2C4_18605	COG4166	transmembrane transport
MLA2C4_18610	COG1301	dicarboxylic acid transport
MLA2C4_18615	COG1316	TRANSCRIPTIONal
MLA2C4_18625	COG1595	DNA-templated transcription, initiation
MLA2C4_18630	COG0346	lactoylglutathione lyase activity
MLA2C4_18640	COG1131	(ABC) transporter
MLA2C4_18675	COG0673	inositol 2-dehydrogenase activity
MLA2C4_18680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLA2C4_18685	COG0187	DNA topoisomerase II activity
MLA2C4_18690	COG1832	CoA-binding protein
MLA2C4_18695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLA2C4_18700	COG0745	RESPONSE REGULATOR receiver
MLA2C4_18720	COG4841	protein insertion into membrane
MLA2C4_18725	COG0824	Thioesterase
MLA2C4_18790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MLA2C4_18800	COG2274	protein secretion by the type I secretion system
MLA2C4_18805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLA2C4_18815	COG0726	polysaccharide deacetylase
MLA2C4_18835	COG2211	Major facilitator Superfamily
MLA2C4_18845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLA2C4_18860	COG0183	Belongs to the thiolase family
MLA2C4_18865	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_18870	COG1268	BioY protein
MLA2C4_18875	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_18915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_18925	COG5002	protein histidine kinase activity
MLA2C4_18930	COG0400	carboxylic ester hydrolase activity
MLA2C4_18935	COG0346	lactoylglutathione lyase activity
MLA2C4_18940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLA2C4_18945	COG0069	glutamate synthase activity
MLA2C4_18950	COG1902	pentaerythritol trinitrate reductase activity
MLA2C4_18955	COG1329	Transcriptional regulator
MLA2C4_18960	COG0010	Belongs to the arginase family
MLA2C4_18985	COG2226	methyltransferase
MLA2C4_19025	COG3344	reverse transcriptase
MLA2C4_19035	COG4846	Membrane protein involved in cytochrome C biogenesis
MLA2C4_19040	COG0785	Cytochrome C biogenesis protein
MLA2C4_19075	COG1131	(ABC) transporter
MLA2C4_19090	COG0583	DNA-binding transcription factor activity
MLA2C4_19100	COG1346	cytolysis
MLA2C4_19120	COG5632	N-Acetylmuramoyl-L-alanine amidase
MLA2C4_19120	COG3409	Peptidoglycan-binding domain 1 protein
MLA2C4_19140	COG1132	(ABC) transporter
MLA2C4_19145	COG1132	(ABC) transporter
MLA2C4_19175	COG3639	organic phosphonate transmembrane transporter activity
MLA2C4_19185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLA2C4_19190	COG0737	Belongs to the 5'-nucleotidase family
MLA2C4_19200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MLA2C4_19220	COG1695	Transcriptional regulator
MLA2C4_19225	COG1132	(ABC) transporter
MLA2C4_19255	COG0367	asparagine synthase
MLA2C4_19260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MLA2C4_19270	COG1181	Belongs to the D-alanine--D-alanine ligase family
MLA2C4_19275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MLA2C4_19310	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_19320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLA2C4_19320	COG0463	Glycosyl transferase, family 2
MLA2C4_19325	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_19330	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_19335	COG1086	Polysaccharide biosynthesis protein
MLA2C4_19340	COG0489	protein tyrosine kinase activity
MLA2C4_19345	COG3944	biosynthesis protein
MLA2C4_19350	COG0174	glutamine synthetase
MLA2C4_19355	COG0789	Transcriptional regulator
MLA2C4_19360	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MLA2C4_19365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLA2C4_19370	COG2860	membrane
MLA2C4_19375	COG0464	growth
MLA2C4_19405	COG3584	3D domain protein
MLA2C4_19405	COG1388	LysM domain
MLA2C4_19410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MLA2C4_19410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLA2C4_19410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MLA2C4_19415	COG1105	Belongs to the carbohydrate kinase PfkB family
MLA2C4_19420	COG1349	DNA-binding transcription factor activity
MLA2C4_19425	COG1979	alcohol dehydrogenase
MLA2C4_19430	COG2322	membrane
MLA2C4_19440	COG1113	amino acid transport
MLA2C4_19455	COG1473	amidohydrolase
MLA2C4_19460	COG1408	metallophosphoesterase
MLA2C4_19465	COG2116	formate transmembrane transporter activity
MLA2C4_19475	COG0454	-acetyltransferase
MLA2C4_19480	COG2217	Heavy metal translocating P-type atpase
MLA2C4_19485	COG2608	mercury ion transmembrane transporter activity
MLA2C4_19490	COG1937	Protein conserved in bacteria
MLA2C4_19500	COG2819	hydrolase of the alpha beta superfamily
MLA2C4_19505	COG1120	ATPase activity
MLA2C4_19510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_19515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_19520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_19530	COG0708	Exodeoxyribonuclease III
MLA2C4_19535	COG2169	Transcriptional regulator
MLA2C4_19540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLA2C4_19545	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLA2C4_19555	COG2364	Membrane
MLA2C4_19575	COG0346	lactoylglutathione lyase activity
MLA2C4_19580	COG3300	MHYT domain
MLA2C4_19580	COG5001	Diguanylate cyclase
MLA2C4_19620	COG1346	cytolysis
MLA2C4_19630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLA2C4_19640	COG2188	Transcriptional regulator
MLA2C4_19645	COG2723	6-phospho-beta-galactosidase activity
MLA2C4_19650	COG0823	Involved in the tonB-independent uptake of proteins
MLA2C4_19655	COG1404	Belongs to the peptidase S8 family
MLA2C4_19660	COG3773	Cell wall hydrolase
MLA2C4_19675	COG1368	sulfuric ester hydrolase activity
MLA2C4_19680	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLA2C4_19695	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MLA2C4_19720	COG4550	Control of competence regulator ComK, YlbF/YmcA
MLA2C4_19730	COG1013	pyruvate-flavodoxin oxidoreductase activity
MLA2C4_19735	COG0674	pyruvate-flavodoxin oxidoreductase activity
MLA2C4_19735	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MLA2C4_19745	COG2359	stage V sporulation protein S
MLA2C4_19750	COG1692	metallophosphoesterase
MLA2C4_19780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLA2C4_19785	COG1426	Protein conserved in bacteria
MLA2C4_19800	COG0300	oxidoreductase activity
MLA2C4_19805	COG0612	Peptidase, M16
MLA2C4_19810	COG0612	Peptidase, M16
MLA2C4_19835	COG2188	Transcriptional regulator
MLA2C4_19845	COG1674	ftsk spoiiie
MLA2C4_19855	COG0740	serine-type endopeptidase activity
MLA2C4_19860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLA2C4_19870	COG0527	aspartate kinase activity
MLA2C4_19875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLA2C4_19880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLA2C4_19885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLA2C4_19890	COG1873	PFAM PRC-barrel domain
MLA2C4_19895	COG0612	Peptidase, M16
MLA2C4_19900	COG0726	polysaccharide deacetylase
MLA2C4_19915	COG0196	riboflavin kinase activity
MLA2C4_19930	COG1550	Protein conserved in bacteria
MLA2C4_19940	COG1358	cellular component organization or biogenesis
MLA2C4_19945	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MLA2C4_19950	COG0195	Participates in both transcription termination and antitermination
MLA2C4_19970	COG0750	zinc metalloprotease
MLA2C4_19975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MLA2C4_19980	COG4589	Belongs to the CDS family
MLA2C4_19995	COG0528	UMP kinase activity
MLA2C4_20025	COG4974	Belongs to the 'phage' integrase family
MLA2C4_20035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLA2C4_20040	COG0758	DNA mediated transformation
MLA2C4_20045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLA2C4_20085	COG1837	Belongs to the UPF0109 family
MLA2C4_20095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLA2C4_20105	COG0552	protein localization to endoplasmic reticulum
MLA2C4_20110	COG1196	nuclear chromosome segregation
MLA2C4_20125	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_20130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MLA2C4_20145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLA2C4_20150	COG1461	Dihydroxyacetone kinase
MLA2C4_20155	COG1302	Protein conserved in bacteria
MLA2C4_20170	COG1564	THIamine pyrophosphokinase
MLA2C4_20175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MLA2C4_20185	COG0515	serine threonine protein kinase
MLA2C4_20185	COG2815	serine threonine protein kinase
MLA2C4_20190	COG0631	protein serine/threonine phosphatase activity
MLA2C4_20200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLA2C4_20200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLA2C4_20215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLA2C4_20220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLA2C4_20230	COG0194	GDP metabolic process
MLA2C4_20240	COG1561	YicC-like family, N-terminal region
MLA2C4_20245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MLA2C4_20265	COG0006	proline dipeptidase activity
MLA2C4_20285	COG3069	C4-dicarboxylate transmembrane transporter activity
MLA2C4_20345	COG0564	pseudouridine synthase activity
MLA2C4_20365	COG3599	regulation of cell shape
MLA2C4_20370	COG2302	S4 RNA-binding domain
MLA2C4_20375	COG0762	integral membrane protein
MLA2C4_20385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLA2C4_20395	COG1873	PFAM PRC-barrel domain
MLA2C4_20400	COG1191	sigma factor activity
MLA2C4_20405	COG1191	sigma factor activity
MLA2C4_20415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLA2C4_20420	COG0849	cell division
MLA2C4_20425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MLA2C4_20435	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLA2C4_20440	COG0772	Belongs to the SEDS family
MLA2C4_20455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLA2C4_20460	COG0768	penicillin binding
MLA2C4_20470	COG4839	cell division protein FtsL
MLA2C4_20485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLA2C4_20505	COG1399	metal-binding, possibly nucleic acid-binding protein
MLA2C4_20515	COG3480	Lon protease (S16) C-terminal proteolytic domain
MLA2C4_20520	COG1752	Esterase of the alpha-beta hydrolase superfamily
MLA2C4_20525	COG3314	Sporulation integral membrane protein YlbJ
MLA2C4_20535	COG0742	ribosomal rna small subunit methyltransferase
MLA2C4_20550	COG3679	Belongs to the UPF0342 family
MLA2C4_20555	COG0406	alpha-ribazole phosphatase activity
MLA2C4_20570	COG2340	Cysteine-rich secretory protein family
MLA2C4_20580	COG3336	cytochrome c oxidase
MLA2C4_20615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLA2C4_20625	COG0772	Belongs to the SEDS family
MLA2C4_20635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLA2C4_20640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MLA2C4_20650	COG4896	Protein conserved in bacteria
MLA2C4_20675	COG0483	inositol monophosphate 1-phosphatase activity
MLA2C4_20695	COG1982	Orn Lys Arg decarboxylase major
MLA2C4_20755	COG0022	dehydrogenase e1 component
MLA2C4_20760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MLA2C4_20775	COG0561	phosphatase activity
MLA2C4_20790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLA2C4_20795	COG0569	domain protein
MLA2C4_20815	COG0583	DNA-binding transcription factor activity
MLA2C4_20820	COG0517	IMP dehydrogenase activity
MLA2C4_20830	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MLA2C4_20835	COG4703	Protein of unknown function (DUF1797)
MLA2C4_20850	COG2200	EAL domain
MLA2C4_20855	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_20860	COG1408	metallophosphoesterase
MLA2C4_20875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MLA2C4_20905	COG0675	Transposase, IS605 OrfB family
MLA2C4_20915	COG2814	Major facilitator Superfamily
MLA2C4_20940	COG3209	COG3209 Rhs family protein
MLA2C4_20950	COG2205	protein histidine kinase activity
MLA2C4_20960	COG0436	Aminotransferase
MLA2C4_20965	COG1609	Transcriptional regulator
MLA2C4_20970	COG3833	ABC-type maltose transport systems, permease component
MLA2C4_20975	COG1175	transmembrane transport
MLA2C4_20980	COG2182	Extracellular solute-binding protein
MLA2C4_20990	COG0366	Alpha amylase catalytic
MLA2C4_20995	COG3842	ATPase activity
MLA2C4_21035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLA2C4_21040	COG0183	Belongs to the thiolase family
MLA2C4_21075	COG1695	Transcriptional regulator
MLA2C4_21080	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_21100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MLA2C4_21105	COG0436	Aminotransferase
MLA2C4_21140	COG2084	Dehydrogenase
MLA2C4_21150	COG2203	Gaf domain
MLA2C4_21150	COG2199	diguanylate cyclase activity
MLA2C4_21155	COG0778	Nitroreductase
MLA2C4_21180	COG2190	(PTS) system
MLA2C4_21180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLA2C4_21180	COG1263	PTS System
MLA2C4_21185	COG3711	transcriptional antiterminator
MLA2C4_21205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLA2C4_21235	COG1547	Domain of unknown function (DUF309)
MLA2C4_21240	COG0456	acetyltransferase
MLA2C4_21250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLA2C4_21255	COG4086	secreted protein
MLA2C4_21260	COG0561	phosphatase activity
MLA2C4_21265	COG0697	spore germination
MLA2C4_21280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLA2C4_21305	COG0733	neurotransmitter:sodium symporter activity
MLA2C4_21325	COG1686	Belongs to the peptidase S11 family
MLA2C4_21335	COG1725	Transcriptional regulator
MLA2C4_21340	COG1131	(ABC) transporter
MLA2C4_21360	COG1846	Transcriptional regulator
MLA2C4_21375	COG0598	Magnesium transport protein CorA
MLA2C4_21400	COG4974	Belongs to the 'phage' integrase family
MLA2C4_21410	COG0735	belongs to the Fur family
MLA2C4_21415	COG1300	Membrane
MLA2C4_21440	COG0667	Aldo Keto reductase
MLA2C4_21445	COG0656	L-ascorbic acid biosynthetic process
MLA2C4_21450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLA2C4_21450	COG0456	acetyltransferase
MLA2C4_21460	COG0737	Belongs to the 5'-nucleotidase family
MLA2C4_21460	COG1525	nuclease
MLA2C4_21460	COG4085	toxin activity
MLA2C4_21470	COG0596	Alpha beta hydrolase
MLA2C4_21475	COG2056	Na+-H+ antiporter family
MLA2C4_21480	COG1609	Transcriptional regulator
MLA2C4_21485	COG0456	acetyltransferase
MLA2C4_21490	COG1073	alpha beta
MLA2C4_21510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLA2C4_21510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLA2C4_21515	COG0307	riboflavin synthase, alpha
MLA2C4_21540	COG4106	trans-aconitate 2-methyltransferase activity
MLA2C4_21545	COG1073	alpha beta
MLA2C4_21545	COG2226	methyltransferase
MLA2C4_21560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLA2C4_21575	COG0737	Belongs to the 5'-nucleotidase family
MLA2C4_21585	COG1522	sequence-specific DNA binding
MLA2C4_21605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MLA2C4_21630	COG0300	oxidoreductase activity
MLA2C4_21635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_21640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLA2C4_21645	COG1760	l-serine dehydratase
MLA2C4_21650	COG1760	l-serine dehydratase
MLA2C4_21675	COG1285	pathogenesis
MLA2C4_21680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLA2C4_21690	COG2195	Cleaves the N-terminal amino acid of tripeptides
MLA2C4_21695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_21705	COG1376	ErfK ybiS ycfS ynhG family protein
MLA2C4_21710	COG4129	membrane
MLA2C4_21715	COG1126	abc transporter atp-binding protein
MLA2C4_21720	COG0765	amino acid transport
MLA2C4_21725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLA2C4_21745	COG2323	membrane
MLA2C4_21750	COG0772	Belongs to the SEDS family
MLA2C4_21755	COG0508	dehydrogenase complex catalyzes the overall conversion of
MLA2C4_21760	COG0022	dehydrogenase e1 component
MLA2C4_21765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MLA2C4_21770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MLA2C4_21780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MLA2C4_21785	COG0280	phosphate acetyltransferase
MLA2C4_21795	COG3290	protein histidine kinase activity
MLA2C4_21795	COG3829	transcription factor binding
MLA2C4_21805	COG0584	glycerophosphoryl diester phosphodiesterase
MLA2C4_21810	COG3093	addiction module antidote protein HigA
MLA2C4_21820	COG0745	RESPONSE REGULATOR receiver
MLA2C4_21830	COG0750	zinc metalloprotease
MLA2C4_21835	COG0497	DNA recombination
MLA2C4_21845	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MLA2C4_21855	COG0142	geranyltranstransferase activity
MLA2C4_21880	COG1302	Protein conserved in bacteria
MLA2C4_21885	COG0439	Biotin carboxylase
MLA2C4_21890	COG0511	ligase activity, forming carbon-carbon bonds
MLA2C4_21935	COG3854	ATPases associated with a variety of cellular activities
MLA2C4_21960	COG0006	proline dipeptidase activity
MLA2C4_21975	COG3872	metal-dependent enzyme
MLA2C4_21985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MLA2C4_22020	COG0095	Lipoate-protein ligase
MLA2C4_22025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLA2C4_22035	COG1609	Transcriptional regulator
MLA2C4_22045	COG2076	Multidrug Resistance protein
MLA2C4_22050	COG2076	Multidrug Resistance protein
MLA2C4_22085	COG1131	(ABC) transporter
MLA2C4_22090	COG1725	Transcriptional regulator
MLA2C4_22120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MLA2C4_22175	COG4970	Tfp pilus assembly protein FimT
MLA2C4_22185	COG1459	type II secretion system
MLA2C4_22190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLA2C4_22240	COG1410	methionine synthase
MLA2C4_22240	COG0646	methionine synthase
MLA2C4_22245	COG0646	methionine synthase
MLA2C4_22245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MLA2C4_22250	COG0626	cystathionine gamma-synthase activity
MLA2C4_22255	COG0626	cystathionine gamma-synthase activity
MLA2C4_22275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_22285	COG1940	carbohydrate kinase activity
MLA2C4_22290	COG4483	Protein conserved in bacteria
MLA2C4_22295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLA2C4_22305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MLA2C4_22310	COG0704	Plays a role in the regulation of phosphate uptake
MLA2C4_22320	COG0581	inorganic phosphate transmembrane transporter activity
MLA2C4_22325	COG0573	inorganic phosphate transmembrane transporter activity
MLA2C4_22330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MLA2C4_22340	COG0477	Major facilitator Superfamily
MLA2C4_22345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLA2C4_22370	COG0735	belongs to the Fur family
MLA2C4_22375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MLA2C4_22380	COG1121	(ABC) transporter
MLA2C4_22385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_22415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLA2C4_22420	COG2384	SAM-dependent methyltransferase
MLA2C4_22425	COG2010	Cytochrome c
MLA2C4_22430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLA2C4_22435	COG0358	DNA primase activity
MLA2C4_22445	COG0517	IMP dehydrogenase activity
MLA2C4_22460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLA2C4_22465	COG0295	cytidine deaminase activity
MLA2C4_22470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MLA2C4_22480	COG1480	7TM receptor with intracellular HD hydrolase
MLA2C4_22485	COG1702	phosphate starvation-inducible protein PhoH
MLA2C4_22500	COG1610	YqeY-like protein
MLA2C4_22510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLA2C4_22515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MLA2C4_22545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MLA2C4_22550	COG1733	regulation of RNA biosynthetic process
MLA2C4_22575	COG1466	dna polymerase III delta subunit
MLA2C4_22585	COG2333	competence protein COMEC
MLA2C4_22585	COG0658	competence protein
MLA2C4_22590	COG2131	deaminase
MLA2C4_22595	COG1555	photosystem II stabilization
MLA2C4_22595	COG1596	polysaccharide export
MLA2C4_22600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLA2C4_22605	COG2226	methyltransferase
MLA2C4_22610	COG0799	negative regulation of ribosome biogenesis
MLA2C4_22615	COG1713	HD superfamily hydrolase involved in NAD metabolism
MLA2C4_22625	COG1534	Rna-binding protein
MLA2C4_22635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLA2C4_22640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MLA2C4_22655	COG1191	sigma factor activity
MLA2C4_22665	COG1595	DNA-templated transcription, initiation
MLA2C4_22675	COG2357	RelA SpoT domain protein
MLA2C4_22685	COG1785	Belongs to the alkaline phosphatase family
MLA2C4_22695	COG2267	carboxylic ester hydrolase activity
MLA2C4_22730	COG1404	Belongs to the peptidase S8 family
MLA2C4_22735	COG3186	Phenylalanine-4-hydroxylase
MLA2C4_22745	COG2514	catechol 2,3-dioxygenase activity
MLA2C4_22750	COG2259	Doxx family
MLA2C4_22790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_22805	COG1454	alcohol dehydrogenase
MLA2C4_22805	COG1012	belongs to the aldehyde dehydrogenase family
MLA2C4_22810	COG0626	cystathionine gamma-synthase activity
MLA2C4_22815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MLA2C4_22840	COG0768	penicillin binding
MLA2C4_22870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLA2C4_22900	COG0628	permease
MLA2C4_22920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MLA2C4_22935	COG1104	cysteine desulfurase activity
MLA2C4_22940	COG1959	2 iron, 2 sulfur cluster binding
MLA2C4_22945	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MLA2C4_22960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MLA2C4_22980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLA2C4_22990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MLA2C4_22990	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MLA2C4_22995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLA2C4_23000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLA2C4_23000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLA2C4_23010	COG2244	polysaccharide biosynthetic process
MLA2C4_23015	COG2323	membrane
MLA2C4_23025	COG1862	Preprotein translocase
MLA2C4_23055	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MLA2C4_23065	COG0697	spore germination
MLA2C4_23070	COG0640	Transcriptional regulator
MLA2C4_23095	COG0157	Belongs to the NadC ModD family
MLA2C4_23100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MLA2C4_23105	COG1104	cysteine desulfurase activity
MLA2C4_23110	COG1827	regulation of RNA biosynthetic process
MLA2C4_23115	COG2258	MOSC domain
MLA2C4_23120	COG0077	Prephenate dehydratase
MLA2C4_23125	COG0577	efflux transmembrane transporter activity
MLA2C4_23130	COG0577	efflux transmembrane transporter activity
MLA2C4_23135	COG1136	(ABC) transporter
MLA2C4_23140	COG5002	protein histidine kinase activity
MLA2C4_23145	COG0745	RESPONSE REGULATOR receiver
MLA2C4_23155	COG3290	protein histidine kinase activity
MLA2C4_23165	COG2868	ribosomal protein
MLA2C4_23175	COG1530	ribonuclease E activity
MLA2C4_23180	COG1994	Peptidase M50
MLA2C4_23185	COG0739	heme binding
MLA2C4_23190	COG2894	cell division
MLA2C4_23205	COG1792	Involved in formation and maintenance of cell shape
MLA2C4_23210	COG1077	Cell shape determining protein MreB Mrl
MLA2C4_23235	COG0285	dihydrofolate synthase activity
MLA2C4_23240	COG0525	valine-tRNA ligase activity
MLA2C4_23250	COG1388	LysM domain
MLA2C4_23260	COG0113	porphobilinogen synthase activity
MLA2C4_23265	COG1587	Uroporphyrinogen-III synthase
MLA2C4_23275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MLA2C4_23285	COG1846	Transcriptional regulator
MLA2C4_23290	COG1764	response to oxidative stress
MLA2C4_23305	COG1067	ATP-dependent peptidase activity
MLA2C4_23305	COG0470	DNA polymerase III
MLA2C4_23360	COG0622	Phosphoesterase
MLA2C4_23365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLA2C4_23375	COG5401	PFAM Sporulation and spore germination
MLA2C4_23385	COG0477	Major facilitator Superfamily
MLA2C4_23395	COG1309	transcriptional regulator
MLA2C4_23405	COG2197	response regulator
MLA2C4_23410	COG2233	PERMEase
MLA2C4_23415	COG0402	S-adenosylhomocysteine deaminase activity
MLA2C4_23420	COG1983	PspC domain protein
MLA2C4_23425	COG1396	sequence-specific DNA binding
MLA2C4_23430	COG0697	spore germination
MLA2C4_23440	COG1959	2 iron, 2 sulfur cluster binding
MLA2C4_23445	COG1668	transmembrane transport
MLA2C4_23450	COG4152	abc transporter atp-binding protein
MLA2C4_23455	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MLA2C4_23460	COG1360	Flagellar Motor Protein
MLA2C4_23465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MLA2C4_23470	COG1876	peptidase activity
MLA2C4_23475	COG0824	Thioesterase
MLA2C4_23480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MLA2C4_23485	COG1053	succinate dehydrogenase
MLA2C4_23490	COG2009	succinate dehydrogenase
MLA2C4_23495	COG1719	4-vinyl reductase, 4VR
MLA2C4_23505	COG3118	belongs to the thioredoxin family
MLA2C4_23510	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MLA2C4_23515	COG2086	electron transfer activity
MLA2C4_23520	COG1024	Enoyl-CoA hydratase
MLA2C4_23525	COG1309	transcriptional regulator
MLA2C4_23530	COG0318	PFAM AMP-dependent synthetase and ligase
MLA2C4_23555	COG2318	DinB family
MLA2C4_23580	COG1131	(ABC) transporter
MLA2C4_23585	COG2205	protein histidine kinase activity
MLA2C4_23590	COG0745	RESPONSE REGULATOR receiver
MLA2C4_23595	COG4895	conserved protein (DUF2196)
MLA2C4_23600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MLA2C4_23610	COG4509	Sortase family
MLA2C4_23615	COG1120	ATPase activity
MLA2C4_23630	COG5386	Cell surface protein
MLA2C4_23635	COG5386	Cell surface protein
MLA2C4_23640	COG1114	Component of the transport system for branched-chain amino acids
MLA2C4_23645	COG1187	pseudouridine synthase activity
MLA2C4_23655	COG1796	DNA polymerase
MLA2C4_23655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MLA2C4_23660	COG1286	toxin biosynthetic process
MLA2C4_23690	COG0017	Asparaginyl-tRNA synthetase
MLA2C4_23705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLA2C4_23715	COG1418	mRNA catabolic process
MLA2C4_23735	COG2814	Major facilitator Superfamily
MLA2C4_23740	COG1566	PFAM secretion protein HlyD family protein
MLA2C4_23745	COG1309	transcriptional regulator
MLA2C4_23750	COG1363	Peptidase, m42
MLA2C4_23770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLA2C4_23775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLA2C4_23785	COG1484	DNA-dependent DNA replication
MLA2C4_23790	COG3611	Membrane attachment protein
MLA2C4_23800	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLA2C4_23810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MLA2C4_23815	COG0237	dephospho-CoA kinase activity
MLA2C4_23820	COG1971	Probably functions as a manganese efflux pump
MLA2C4_23830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLA2C4_23830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLA2C4_23835	COG5002	protein histidine kinase activity
MLA2C4_23840	COG0745	RESPONSE REGULATOR receiver
MLA2C4_23860	COG0538	isocitrate dehydrogenase activity
MLA2C4_23865	COG0372	Belongs to the citrate synthase family
MLA2C4_23880	COG0628	permease
MLA2C4_23885	COG3030	protein affecting phage T7 exclusion by the F plasmid
MLA2C4_23910	COG1725	Transcriptional regulator
MLA2C4_23915	COG0281	malic enzyme
MLA2C4_23920	COG0587	DNA-directed DNA polymerase activity
MLA2C4_23955	COG4109	DRTGG domain
MLA2C4_23965	COG0006	proline dipeptidase activity
MLA2C4_24005	COG0662	Cupin 2, conserved barrel domain protein
MLA2C4_24015	COG1476	TRANSCRIPTIONal
MLA2C4_24030	COG1028	Short-chain dehydrogenase reductase Sdr
MLA2C4_24035	COG0589	response to stress
MLA2C4_24075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_24095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLA2C4_24100	COG0827	DNA restriction-modification system
MLA2C4_24105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLA2C4_24110	COG3874	Sporulation protein YtfJ
MLA2C4_24125	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MLA2C4_24135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MLA2C4_24150	COG1104	cysteine desulfurase activity
MLA2C4_24160	COG0583	DNA-binding transcription factor activity
MLA2C4_24165	COG0697	spore germination
MLA2C4_24170	COG1309	transcriptional regulator
MLA2C4_24175	COG1956	GAF domain-containing protein
MLA2C4_24210	COG1595	DNA-templated transcription, initiation
MLA2C4_24220	COG0110	maltose O-acetyltransferase activity
MLA2C4_24225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MLA2C4_24230	COG0454	-acetyltransferase
MLA2C4_24235	COG0517	IMP dehydrogenase activity
MLA2C4_24240	COG0123	including yeast histone deacetylase and acetoin utilization protein
MLA2C4_24260	COG0745	RESPONSE REGULATOR receiver
MLA2C4_24265	COG5002	protein histidine kinase activity
MLA2C4_24305	COG1609	Transcriptional regulator
MLA2C4_24315	COG4851	CamS sex pheromone cAM373 precursor
MLA2C4_24320	COG3118	belongs to the thioredoxin family
MLA2C4_24330	COG2309	aminopeptidase activity
MLA2C4_24355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_24360	COG0697	spore germination
MLA2C4_24365	COG0789	Transcriptional regulator
MLA2C4_24370	COG1695	Transcriptional regulator
MLA2C4_24390	COG1674	ftsk spoiiie
MLA2C4_24405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLA2C4_24415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MLA2C4_24420	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MLA2C4_24425	COG1363	Peptidase, m42
MLA2C4_24435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_24450	COG0510	thiamine kinase activity
MLA2C4_24455	COG1523	belongs to the glycosyl hydrolase 13 family
MLA2C4_24465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MLA2C4_24470	COG1349	DNA-binding transcription factor activity
MLA2C4_24475	COG1187	pseudouridine synthase activity
MLA2C4_24480	COG2244	polysaccharide biosynthetic process
MLA2C4_24485	COG2081	HI0933 family
MLA2C4_24490	COG2814	Major facilitator Superfamily
MLA2C4_24505	COG3832	glyoxalase III activity
MLA2C4_24530	COG1329	Transcriptional regulator
MLA2C4_24555	COG0314	molybdopterin synthase activity
MLA2C4_24560	COG1763	Mo-molybdopterin cofactor biosynthetic process
MLA2C4_24565	COG0303	'Molybdopterin
MLA2C4_24575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MLA2C4_24580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLA2C4_24600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLA2C4_24610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLA2C4_24650	COG2814	Major facilitator Superfamily
MLA2C4_24655	COG0475	glutathione-regulated potassium exporter activity
MLA2C4_24660	COG0490	domain, Protein
MLA2C4_24665	COG0582	viral genome integration into host DNA
MLA2C4_24675	COG1136	(ABC) transporter
MLA2C4_24700	COG1242	4 iron, 4 sulfur cluster binding
MLA2C4_24705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MLA2C4_24710	COG1131	(ABC) transporter
MLA2C4_24720	COG1794	racemase activity, acting on amino acids and derivatives
MLA2C4_24730	COG1131	(ABC) transporter
MLA2C4_24770	COG2267	carboxylic ester hydrolase activity
MLA2C4_24775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLA2C4_24780	COG0671	phosphoesterase, PA-phosphatase related
MLA2C4_24785	COG0438	transferase activity, transferring glycosyl groups
MLA2C4_24795	COG0521	Mo-molybdopterin cofactor biosynthetic process
MLA2C4_24845	COG5002	protein histidine kinase activity
MLA2C4_24850	COG4191	Histidine kinase
MLA2C4_24855	COG2267	carboxylic ester hydrolase activity
MLA2C4_24875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLA2C4_24880	COG1116	anion transmembrane transporter activity
MLA2C4_24885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLA2C4_24910	COG0494	nUDIX hydrolase
MLA2C4_24960	COG0288	reversible hydration of carbon dioxide
MLA2C4_24965	COG1271	oxidase subunit
MLA2C4_24970	COG1294	oxidase, subunit
MLA2C4_24990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_25015	COG1842	Phage shock protein A
MLA2C4_25040	COG3859	Proton-coupled thiamine transporter YuaJ
MLA2C4_25045	COG5002	protein histidine kinase activity
MLA2C4_25050	COG0745	RESPONSE REGULATOR receiver
MLA2C4_25080	COG1597	lipid kinase activity
MLA2C4_25120	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_25140	COG0577	efflux transmembrane transporter activity
MLA2C4_25145	COG1136	(ABC) transporter
MLA2C4_25150	COG2207	Transcriptional regulator
MLA2C4_25150	COG3708	Transcriptional regulator
MLA2C4_25155	COG5658	integral membrane protein
MLA2C4_25160	COG0640	Transcriptional regulator
MLA2C4_25165	COG0745	RESPONSE REGULATOR receiver
MLA2C4_25170	COG2205	protein histidine kinase activity
MLA2C4_25175	COG0577	efflux transmembrane transporter activity
MLA2C4_25180	COG0577	efflux transmembrane transporter activity
MLA2C4_25185	COG1136	(ABC) transporter
MLA2C4_25190	COG0577	efflux transmembrane transporter activity
MLA2C4_25225	COG3964	amidohydrolase
MLA2C4_25250	COG4948	Mandelate Racemase Muconate Lactonizing
MLA2C4_25260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLA2C4_25265	COG0596	Alpha beta hydrolase
MLA2C4_25275	COG1169	isochorismate synthase
MLA2C4_25280	COG1575	Belongs to the MenA family. Type 1 subfamily
MLA2C4_25285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MLA2C4_25290	COG1278	Cold shock
MLA2C4_25305	COG0058	SHG alpha-glucan phosphorylase activity
MLA2C4_25315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLA2C4_25335	COG1404	Belongs to the peptidase S8 family
MLA2C4_25350	COG1595	DNA-templated transcription, initiation
MLA2C4_25480	COG1285	pathogenesis
MLA2C4_25485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MLA2C4_25505	COG2155	Conserved Protein
MLA2C4_25510	COG1098	S1 RNA binding domain
MLA2C4_25515	COG0436	Aminotransferase
MLA2C4_25520	COG1522	sequence-specific DNA binding
MLA2C4_25525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLA2C4_25530	COG2267	carboxylic ester hydrolase activity
MLA2C4_25540	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MLA2C4_25555	COG5018	Exonuclease
MLA2C4_25560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLA2C4_25575	COG0423	glycine-tRNA ligase activity
MLA2C4_25580	COG2050	protein possibly involved in aromatic compounds catabolism
MLA2C4_25590	COG1268	BioY protein
MLA2C4_25600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MLA2C4_25605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLA2C4_25620	COG3584	3D domain protein
MLA2C4_25635	COG1252	NADH dehydrogenase
MLA2C4_25645	COG3708	Transcriptional regulator
MLA2C4_25660	COG0583	DNA-binding transcription factor activity
MLA2C4_25665	COG2814	Major facilitator Superfamily
MLA2C4_25675	COG1683	Conserved Protein
MLA2C4_25700	COG0316	Belongs to the HesB IscA family
MLA2C4_25715	COG1252	NADH dehydrogenase
MLA2C4_25725	COG2274	protein secretion by the type I secretion system
MLA2C4_25730	COG0390	transport system, permease component
MLA2C4_25735	COG2824	Alkylphosphonate utilization operon protein PhnA
MLA2C4_25755	COG4837	Protein of unknown function (DUF1462)
MLA2C4_25760	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MLA2C4_25770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLA2C4_25775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MLA2C4_25790	COG0577	efflux transmembrane transporter activity
MLA2C4_25790	COG1136	(ABC) transporter
MLA2C4_25795	COG2249	NAD(P)H dehydrogenase (quinone) activity
MLA2C4_25805	COG0647	UMP catabolic process
MLA2C4_25815	COG2445	Protein of unknown function DUF86
MLA2C4_25820	COG1494	fructose-1,6-bisphosphatase
MLA2C4_25835	COG0564	pseudouridine synthase activity
MLA2C4_25840	COG4470	Protein conserved in bacteria
MLA2C4_25850	COG0789	Transcriptional regulator
MLA2C4_25855	COG4377	Putative membrane peptidase family (DUF2324)
MLA2C4_25880	COG0739	heme binding
MLA2C4_25890	COG3377	Domain of unknown function (DUF1805)
MLA2C4_25895	COG0737	Belongs to the 5'-nucleotidase family
MLA2C4_25905	COG0719	Fe-S assembly protein
MLA2C4_25910	COG0822	iron-sulfur transferase activity
MLA2C4_25915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLA2C4_25920	COG0719	Fe-S assembly protein
MLA2C4_25925	COG0396	ATPase activity
MLA2C4_25930	COG1464	Belongs to the NlpA lipoprotein family
MLA2C4_25935	COG1464	Belongs to the NlpA lipoprotein family
MLA2C4_25940	COG2011	ABC-type metal ion transport system permease component
MLA2C4_25955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MLA2C4_25960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLA2C4_25970	COG1393	Belongs to the ArsC family
MLA2C4_26020	COG1309	transcriptional regulator
MLA2C4_26025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLA2C4_26030	COG1960	acyl-CoA dehydrogenase activity
MLA2C4_26035	COG0183	Belongs to the thiolase family
MLA2C4_26040	COG1024	Enoyl-CoA hydratase
MLA2C4_26040	COG1250	3-hydroxyacyl-CoA dehydrogenase
MLA2C4_26050	COG1686	Belongs to the peptidase S11 family
MLA2C4_26055	COG0506	proline dehydrogenase activity
MLA2C4_26065	COG0011	TIGRFAM Protein of
MLA2C4_26070	COG0840	transmembrane signaling receptor activity
MLA2C4_26110	COG4974	Belongs to the 'phage' integrase family
MLA2C4_26120	COG2814	Major facilitator Superfamily
MLA2C4_26125	COG0531	amino acid
MLA2C4_26150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLA2C4_26190	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_26200	COG1376	ErfK ybiS ycfS ynhG family protein
MLA2C4_26205	COG0745	RESPONSE REGULATOR receiver
MLA2C4_26210	COG5002	protein histidine kinase activity
MLA2C4_26240	COG0840	transmembrane signaling receptor activity
MLA2C4_26245	COG2151	metal-sulfur cluster biosynthetic enzyme
MLA2C4_26250	COG3227	Zinc metalloprotease (Elastase)
MLA2C4_26255	COG1741	Belongs to the pirin family
MLA2C4_26270	COG0586	Pfam SNARE associated Golgi protein
MLA2C4_26275	COG0475	glutathione-regulated potassium exporter activity
MLA2C4_26280	COG0490	domain, Protein
MLA2C4_26285	COG1115	amino acid carrier protein
MLA2C4_26290	COG0783	Belongs to the Dps family
MLA2C4_26300	COG1611	Belongs to the LOG family
MLA2C4_26320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_26330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_26335	COG1115	amino acid carrier protein
MLA2C4_26340	COG1115	amino acid carrier protein
MLA2C4_26345	COG2910	NAD(P)H-binding
MLA2C4_26360	COG0656	L-ascorbic acid biosynthetic process
MLA2C4_26365	COG2814	Major facilitator Superfamily
MLA2C4_26370	COG1733	regulation of RNA biosynthetic process
MLA2C4_26380	COG1252	NADH dehydrogenase
MLA2C4_26385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLA2C4_26390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MLA2C4_26400	COG3290	protein histidine kinase activity
MLA2C4_26400	COG0840	transmembrane signaling receptor activity
MLA2C4_26435	COG0488	(ABC) transporter
MLA2C4_26440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLA2C4_26450	COG1335	isochorismatase
MLA2C4_26455	COG1522	sequence-specific DNA binding
MLA2C4_26460	COG1522	sequence-specific DNA binding
MLA2C4_26465	COG0288	reversible hydration of carbon dioxide
MLA2C4_26470	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MLA2C4_26475	COG2233	PERMEase
MLA2C4_26510	COG0697	spore germination
MLA2C4_26535	COG0557	exoribonuclease II activity
MLA2C4_26540	COG1647	Serine aminopeptidase, S33
MLA2C4_26545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MLA2C4_26550	COG1346	cytolysis
MLA2C4_26585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MLA2C4_26600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MLA2C4_26625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLA2C4_26640	COG2323	membrane
MLA2C4_26650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLA2C4_26660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MLA2C4_26670	COG1051	belongs to the nudix hydrolase family
MLA2C4_26680	COG0492	ferredoxin-NADP+ reductase activity
MLA2C4_26685	COG0457	Tetratricopeptide repeat
MLA2C4_26690	COG0110	maltose O-acetyltransferase activity
MLA2C4_26710	COG1950	PFAM Membrane protein of
MLA2C4_26720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MLA2C4_26725	COG0556	nucleotide-excision repair
MLA2C4_26740	COG0789	Transcriptional regulator
MLA2C4_26775	COG0583	DNA-binding transcription factor activity
MLA2C4_26785	COG0655	NAD(P)H dehydrogenase (quinone) activity
MLA2C4_26800	COG1132	(ABC) transporter
MLA2C4_26805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLA2C4_26810	COG0793	Belongs to the peptidase S41A family
MLA2C4_26810	COG3409	Peptidoglycan-binding domain 1 protein
MLA2C4_26815	COG2177	Part of the ABC transporter FtsEX involved in
MLA2C4_26820	COG2884	Cell division ATP-binding protein ftsE
MLA2C4_26850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLA2C4_26855	COG1278	Cold shock
MLA2C4_26860	COG1040	competence protein
MLA2C4_26865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLA2C4_26870	COG0791	NLP P60 protein
MLA2C4_26870	COG1388	LysM domain
MLA2C4_26875	COG1733	regulation of RNA biosynthetic process
MLA2C4_26880	COG1307	EDD domain protein, DegV family
MLA2C4_26885	COG1739	Uncharacterized protein family UPF0029
MLA2C4_26890	COG1316	TRANSCRIPTIONal
MLA2C4_26895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MLA2C4_26900	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLA2C4_26905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLA2C4_26915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MLA2C4_26915	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MLA2C4_26935	COG1486	melibiose metabolic process
MLA2C4_26940	COG1447	Phosphotransferase system cellobiose-specific component IIA
MLA2C4_26945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MLA2C4_26970	COG1447	Phosphotransferase system cellobiose-specific component IIA
MLA2C4_26980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MLA2C4_26985	COG1301	dicarboxylic acid transport
MLA2C4_26995	COG0346	lactoylglutathione lyase activity
MLA2C4_27000	COG1511	domain protein
MLA2C4_27005	COG0583	DNA-binding transcription factor activity
MLA2C4_27010	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLA2C4_27015	COG1271	oxidase subunit
MLA2C4_27020	COG1294	oxidase, subunit
MLA2C4_27025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLA2C4_27035	COG1620	l-lactate permease
MLA2C4_27045	COG2389	metal-binding protein
MLA2C4_27060	COG1368	sulfuric ester hydrolase activity
MLA2C4_27070	COG0791	NLP P60 protein
MLA2C4_27070	COG1388	LysM domain
MLA2C4_27075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLA2C4_27085	COG1215	transferase activity, transferring glycosyl groups
MLA2C4_27090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MLA2C4_27100	COG1388	LysM domain
MLA2C4_27100	COG3584	3D domain protein
MLA2C4_27125	COG4715	Zinc finger, swim domain protein
MLA2C4_27130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MLA2C4_27160	COG1191	sigma factor activity
MLA2C4_27170	COG0577	efflux transmembrane transporter activity
MLA2C4_27175	COG1136	(ABC) transporter
MLA2C4_27200	COG5002	protein histidine kinase activity
MLA2C4_27205	COG0745	RESPONSE REGULATOR receiver
MLA2C4_27210	COG1482	cell wall glycoprotein biosynthetic process
MLA2C4_27215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MLA2C4_27215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLA2C4_27215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MLA2C4_27220	COG3711	transcriptional antiterminator
MLA2C4_27220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLA2C4_27225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MLA2C4_27240	COG1482	cell wall glycoprotein biosynthetic process
MLA2C4_27250	COG0662	Cupin 2, conserved barrel domain protein
MLA2C4_27250	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MLA2C4_27280	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MLA2C4_27285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLA2C4_27295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MLA2C4_27300	COG4464	protein tyrosine phosphatase activity
MLA2C4_27305	COG0489	protein tyrosine kinase activity
MLA2C4_27310	COG3944	biosynthesis protein
MLA2C4_27315	COG0489	protein tyrosine kinase activity
MLA2C4_27330	COG1609	Transcriptional regulator
MLA2C4_27340	COG0739	heme binding
MLA2C4_27355	COG3279	Response regulator of the LytR AlgR family
MLA2C4_27365	COG2385	sporulation resulting in formation of a cellular spore
MLA2C4_27370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLA2C4_27380	COG4836	Membrane
MLA2C4_27385	COG1007	ATP synthesis coupled electron transport
MLA2C4_27390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MLA2C4_27395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MLA2C4_27405	COG0839	Belongs to the complex I subunit 6 family
MLA2C4_27425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MLA2C4_27440	COG5001	Diguanylate cyclase
MLA2C4_27440	COG3300	MHYT domain
MLA2C4_27490	COG0356	it plays a direct role in the translocation of protons across the membrane
MLA2C4_27525	COG0698	ribose 5-phosphate isomerase
MLA2C4_27535	COG2190	(PTS) system
MLA2C4_27540	COG2259	Doxx family
MLA2C4_27545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLA2C4_27565	COG0009	L-threonylcarbamoyladenylate synthase
MLA2C4_27580	COG2890	protein-(glutamine-N5) methyltransferase activity
MLA2C4_27610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLA2C4_27615	COG1494	fructose-1,6-bisphosphatase
MLA2C4_27620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLA2C4_27635	COG4821	SIS domain
MLA2C4_27655	COG1960	acyl-CoA dehydrogenase activity
MLA2C4_27660	COG1960	acyl-CoA dehydrogenase activity
MLA2C4_27665	COG1250	3-hydroxyacyl-CoA dehydrogenase
MLA2C4_27670	COG0183	Belongs to the thiolase family
MLA2C4_27675	COG2181	nitrate reductase activity
MLA2C4_27675	COG0247	lactate metabolic process
MLA2C4_27680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLA2C4_27690	COG3300	MHYT domain
MLA2C4_27690	COG5001	Diguanylate cyclase
MLA2C4_27710	COG2197	response regulator
MLA2C4_27715	COG4585	Histidine kinase
MLA2C4_27720	COG0842	Transport permease protein
MLA2C4_27725	COG1131	(ABC) transporter
MLA2C4_27730	COG0024	Methionine aminopeptidase
MLA2C4_27735	COG2234	aminopeptidase activity
MLA2C4_27765	COG1595	DNA-templated transcription, initiation
MLA2C4_27780	COG1619	proteins homologs of microcin C7 resistance protein MccF
MLA2C4_27800	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLA2C4_27805	COG2814	Major facilitator Superfamily
MLA2C4_27810	COG0789	Transcriptional regulator
MLA2C4_27815	COG0584	glycerophosphoryl diester phosphodiesterase
MLA2C4_27820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MLA2C4_27830	COG1994	Peptidase M50
MLA2C4_27840	COG1078	dGTPase activity
MLA2C4_27845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MLA2C4_27850	COG1120	ATPase activity
MLA2C4_27855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_27860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLA2C4_27875	COG0095	Lipoate-protein ligase
MLA2C4_27880	COG0640	Transcriptional regulator
MLA2C4_27885	COG0346	lactoylglutathione lyase activity
MLA2C4_27890	COG0798	PFAM Bile acid sodium symporter
MLA2C4_27915	COG0280	phosphate acetyltransferase
MLA2C4_27930	COG3773	Cell wall hydrolase
MLA2C4_27940	COG2363	Small membrane protein
MLA2C4_27950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MLA2C4_27955	COG2233	PERMEase
MLA2C4_27960	COG0561	phosphatase activity
MLA2C4_27965	COG2814	Major facilitator Superfamily
MLA2C4_27975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MLA2C4_27980	COG1131	(ABC) transporter
MLA2C4_27985	COG2755	lipolytic protein G-D-S-L family
MLA2C4_27990	COG1609	Transcriptional regulator
MLA2C4_28000	COG0460	homoserine dehydrogenase
MLA2C4_28020	COG1011	Hydrolase
MLA2C4_28025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MLA2C4_28035	COG2197	response regulator
MLA2C4_28040	COG2203	Gaf domain
MLA2C4_28040	COG4585	Histidine kinase
MLA2C4_28045	COG0351	phosphomethylpyrimidine kinase
MLA2C4_28060	COG2879	small protein
MLA2C4_28065	COG1966	Carbon starvation protein
MLA2C4_28070	COG3279	Response regulator of the LytR AlgR family
MLA2C4_28075	COG0477	Major facilitator Superfamily
MLA2C4_28100	COG0840	transmembrane signaling receptor activity
MLA2C4_28110	COG1607	acyl-coa hydrolase
MLA2C4_28125	COG0488	(ABC) transporter
MLA2C4_28145	COG0463	Glycosyl transferase, family 2
MLA2C4_28150	COG1309	transcriptional regulator
MLA2C4_28155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLA2C4_28160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLA2C4_28160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLA2C4_28165	COG0628	permease
MLA2C4_28180	COG3279	Response regulator of the LytR AlgR family
MLA2C4_28185	COG3275	phosphorelay sensor kinase activity
MLA2C4_28190	COG2814	Major facilitator Superfamily
MLA2C4_28195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MLA2C4_28200	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLA2C4_28210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLA2C4_28260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MLA2C4_28265	COG1272	protein, Hemolysin III
MLA2C4_28295	COG1164	Oligoendopeptidase f
MLA2C4_28325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLA2C4_28330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MLA2C4_28335	COG4853	Protein conserved in bacteria
MLA2C4_28340	COG4863	YycH protein
MLA2C4_28345	COG5002	protein histidine kinase activity
MLA2C4_28350	COG0745	RESPONSE REGULATOR receiver
MLA2C4_28380	COG0305	Participates in initiation and elongation during chromosome replication
MLA2C4_28390	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MLA2C4_28395	COG4241	membrane
MLA2C4_28405	COG0629	single-stranded DNA binding
MLA2C4_28415	COG0012	GTP binding
MLA2C4_28420	COG4481	Protein conserved in bacteria
MLA2C4_28425	COG0668	transmembrane transport
MLA2C4_28435	COG1475	DNA binding
MLA2C4_28440	COG1192	Involved in chromosome partitioning
MLA2C4_28465	COG1847	R3H domain protein
MLA2C4_28470	COG0706	membrane insertase activity