MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 74 87 - T 01-11-2018 IPR018313 Solute-binding protein family 3, conserved site MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 SMART SM00062 50 273 3.9E-84 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 SMART SM00079 50 272 1.5E-6 T 01-11-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 Gene3D G3DSA:3.40.190.10 138 235 2.3E-83 T 01-11-2018 MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 SUPERFAMILY SSF53850 4 273 6.29E-71 T 01-11-2018 MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 Gene3D G3DSA:3.40.190.10 51 269 2.3E-83 T 01-11-2018 MLA2C4_03385 1ff618f9b7a91e052d746f4be3998fde 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 272 3.5E-59 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 311 1.8E-38 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 SUPERFAMILY SSF56601 328 699 1.17E-66 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 Gene3D G3DSA:1.10.10.1230 93 202 7.4E-223 T 01-11-2018 MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 Gene3D G3DSA:3.40.710.10 326 687 7.4E-223 T 01-11-2018 MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 SUPERFAMILY SSF56519 62 326 6.8E-39 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 Gene3D G3DSA:3.90.1310.30 68 580 7.4E-223 T 01-11-2018 MLA2C4_16145 2a0941cdf9d65e83bde9f44c4d42c721 717 Pfam PF00905 Penicillin binding protein transpeptidase domain 357 693 5.8E-70 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 SMART SM00448 2 115 3.0E-31 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 SUPERFAMILY SSF52172 1 131 1.1E-34 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 4.6E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 4.6E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 4.6E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 SMART SM00421 152 209 1.4E-25 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.9E-19 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 SUPERFAMILY SSF46894 146 214 1.33E-21 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 Gene3D G3DSA:3.40.50.12740 2 215 5.2E-71 T 01-11-2018 MLA2C4_01265 a60b4f44f7b621554907cbef0aa31714 218 Pfam PF00072 Response regulator receiver domain 4 115 3.1E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_02515 506e08d4929f9bd4c3546ae719add013 265 Pfam PF14167 YfkD-like protein 34 263 1.4E-105 T 01-11-2018 IPR025548 YfkD-like protein MLA2C4_19180 4583e8eed2bf8e526cb6de748af47937 257 Gene3D G3DSA:3.40.50.300 1 254 4.9E-62 T 01-11-2018 MLA2C4_19180 4583e8eed2bf8e526cb6de748af47937 257 SUPERFAMILY SSF52540 1 237 1.17E-63 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19180 4583e8eed2bf8e526cb6de748af47937 257 SMART SM00382 27 223 1.1E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19180 4583e8eed2bf8e526cb6de748af47937 257 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_19180 4583e8eed2bf8e526cb6de748af47937 257 Pfam PF00005 ABC transporter 18 174 3.9E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19180 4583e8eed2bf8e526cb6de748af47937 257 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 6.6E-109 T 01-11-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 Gene3D G3DSA:3.40.50.1220 182 335 1.9E-49 T 01-11-2018 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 01-11-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 3.2E-40 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 Gene3D G3DSA:3.40.50.970 348 564 2.3E-63 T 01-11-2018 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 SUPERFAMILY SSF52518 358 553 4.83E-64 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 SUPERFAMILY SSF52467 185 351 1.93E-46 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 319 5.7E-35 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 SUPERFAMILY SSF52518 1 170 6.58E-49 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 Gene3D G3DSA:3.40.50.970 2 180 9.9E-62 T 01-11-2018 MLA2C4_12320 7fe156f0715799737490b0cea8a5bd0d 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 1.1E-48 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 PRINTS PR00108 Thymidylate synthase family signature 169 188 9.6E-50 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 PRINTS PR00108 Thymidylate synthase family signature 195 210 9.6E-50 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 PRINTS PR00108 Thymidylate synthase family signature 46 67 9.6E-50 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 PRINTS PR00108 Thymidylate synthase family signature 213 239 9.6E-50 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 PRINTS PR00108 Thymidylate synthase family signature 251 268 9.6E-50 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 Pfam PF00303 Thymidylate synthase 7 318 1.7E-121 T 01-11-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 318 2.2E-170 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 SUPERFAMILY SSF55831 3 318 5.1E-139 T 01-11-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 ProSitePatterns PS00091 Thymidylate synthase active site. 180 208 - T 01-11-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 Hamap MF_00008 Thymidylate synthase [thyA]. 5 318 40.786 T 01-11-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_11195 8399cf37f3c68179ba407a4816f8078b 318 Gene3D G3DSA:3.30.572.10 3 318 1.3E-145 T 01-11-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Pfam PF05043 Mga helix-turn-helix domain 94 164 1.1E-6 T 01-11-2018 IPR007737 Mga helix-turn-helix domain MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 SUPERFAMILY SSF46785 1 45 4.54E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Pfam PF08279 HTH domain 4 60 1.8E-8 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 554 570 - T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Pfam PF00874 PRD domain 197 280 2.1E-12 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Pfam PF00874 PRD domain 309 397 1.7E-18 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Gene3D G3DSA:3.40.50.2300 408 495 1.6E-11 T 01-11-2018 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Gene3D G3DSA:3.40.930.10 510 647 5.5E-30 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 SUPERFAMILY SSF55804 506 645 4.58E-29 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 SUPERFAMILY SSF63520 303 400 3.79E-21 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Gene3D G3DSA:1.10.10.10 1 57 1.4E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Gene3D G3DSA:1.10.10.10 79 152 1.8E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 SUPERFAMILY SSF52794 408 487 1.99E-7 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Gene3D G3DSA:1.10.1790.10 301 399 3.1E-20 T 01-11-2018 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Gene3D G3DSA:1.10.1790.10 188 282 1.5E-7 T 01-11-2018 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 SUPERFAMILY SSF63520 185 281 1.2E-13 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 SUPERFAMILY SSF46785 92 151 3.74E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_27220 71aaacec71340419066a2a7b4476e4e4 648 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 511 647 5.7E-30 T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_15705 d7b5a7f484e345fae45daf08465dcf18 131 SUPERFAMILY SSF54593 1 124 9.26E-21 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15705 d7b5a7f484e345fae45daf08465dcf18 131 Gene3D G3DSA:3.10.180.10 2 121 2.2E-26 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15705 d7b5a7f484e345fae45daf08465dcf18 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 119 3.6E-11 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 2090 2249 1.45E-23 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 3702 3732 - T 01-11-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.10 2531 2907 6.4E-118 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1526 1915 4.3E-131 T 01-11-2018 IPR010071 Amino acid adenylation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3018 3407 3.5E-132 T 01-11-2018 IPR010071 Amino acid adenylation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 504 893 2.2E-132 T 01-11-2018 IPR010071 Amino acid adenylation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00668 Condensation domain 12 462 2.7E-104 T 01-11-2018 IPR001242 Condensation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00668 Condensation domain 1059 1484 3.1E-114 T 01-11-2018 IPR001242 Condensation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00668 Condensation domain 2526 2976 1.6E-101 T 01-11-2018 IPR001242 Condensation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00668 Condensation domain 2091 2510 2.4E-72 T 01-11-2018 IPR001242 Condensation domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 204 449 5.89E-47 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3513 3528 - T 01-11-2018 IPR006162 Phosphopantetheine attachment site MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:1.10.1200.10 1987 2063 2.2E-19 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF53474 3596 3905 9.48E-31 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF13193 AMP-binding enzyme C-terminal domain 877 950 3.1E-9 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF13193 AMP-binding enzyme C-terminal domain 1899 1972 3.1E-9 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF13193 AMP-binding enzyme C-terminal domain 3391 3464 3.1E-9 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3133 3144 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 999 1014 - T 01-11-2018 IPR006162 Phosphopantetheine attachment site MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.40.50.1820 966 1064 8.8E-24 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.40.50.1820 3480 3576 6.5E-24 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 1062 1224 5.34E-39 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 1226 1471 5.11E-50 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1641 1652 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.10 1065 1411 1.0E-128 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.30 2240 2500 1.2E-49 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF56801 444 988 6.41E-156 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.40.50.12780 468 863 9.2E-140 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.40.50.12780 2982 3377 1.4E-139 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.40.50.12780 1491 1885 4.1E-138 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.10 2064 2239 7.2E-47 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF47336 967 1040 8.24E-17 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.30 205 459 6.7E-118 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00326 Prolyl oligopeptidase family 3696 3876 1.5E-5 T 01-11-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2021 2036 - T 01-11-2018 IPR006162 Phosphopantetheine attachment site MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 2256 2494 8.78E-23 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF56801 1464 2010 1.57E-156 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 17 203 4.78E-35 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF47336 3481 3555 5.23E-17 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00550 Phosphopantetheine attachment site 3492 3553 1.3E-9 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00550 Phosphopantetheine attachment site 2000 2058 7.1E-9 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00550 Phosphopantetheine attachment site 978 1039 1.4E-9 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.300.30 3378 3479 6.8E-31 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.300.30 1886 1986 6.8E-31 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.300.30 864 965 6.8E-31 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.30 1228 1469 1.0E-128 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2373 2516 5.2E-29 T 01-11-2018 IPR010060 Non-ribosomal peptide synthase MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 2718 2963 5.34E-46 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 ProSitePatterns PS00455 Putative AMP-binding domain signature. 619 630 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF56801 2958 3502 1.22E-155 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.10 17 393 6.7E-118 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.40.50.1820 3619 3882 6.5E-37 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00501 AMP-binding enzyme 1505 1891 3.4E-104 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00501 AMP-binding enzyme 2997 3383 4.6E-105 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Pfam PF00501 AMP-binding enzyme 483 869 6.9E-106 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF52777 2531 2717 2.22E-34 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 Gene3D G3DSA:3.30.559.30 2719 2973 6.4E-118 T 01-11-2018 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SUPERFAMILY SSF47336 1989 2058 1.1E-14 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SMART SM00823 Phosphopantetheine attachment site 974 1044 0.058 T 01-11-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MLA2C4_18780 ee55a410da39fb8df86301bbd9587517 3909 SMART SM00823 Phosphopantetheine attachment site 3488 3558 0.037 T 01-11-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SUPERFAMILY SSF48452 535 667 1.2E-13 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Pfam PF00069 Protein kinase domain 36 233 8.9E-12 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Gene3D G3DSA:1.25.40.10 667 781 1.6E-8 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Gene3D G3DSA:1.10.510.10 34 306 8.5E-14 T 01-11-2018 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Pfam PF14559 Tetratricopeptide repeat 818 881 1.2E-5 T 01-11-2018 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Gene3D G3DSA:1.25.40.10 528 666 1.1E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Gene3D G3DSA:1.25.40.10 782 887 2.6E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SUPERFAMILY SSF56112 36 305 9.56E-16 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SUPERFAMILY SSF81901 646 872 2.88E-19 T 01-11-2018 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 Pfam PF13432 Tetratricopeptide repeat 570 633 1.3E-4 T 01-11-2018 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SMART SM00028 603 636 11.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SMART SM00028 757 796 160.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SMART SM00028 566 599 160.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SMART SM00028 838 871 90.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SMART SM00028 677 710 20.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_11050 a6933686f4af8a74799342b2f882009c 891 SMART SM00028 804 837 1.1 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 Pfam PF01264 Chorismate synthase 1 364 3.2E-124 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 Gene3D G3DSA:3.60.150.10 1 390 6.9E-156 T 01-11-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 SUPERFAMILY SSF103263 1 389 1.96E-151 T 01-11-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 370 7.2E-130 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.82 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_15565 87425a15073c2e8d6f5bdd934d43e05e 390 PIRSF PIRSF001456 1 387 8.3E-131 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_17805 f16aafa01494827d3ebf669b84f7bf2f 187 Gene3D G3DSA:3.40.630.30 3 180 6.2E-36 T 01-11-2018 MLA2C4_17805 f16aafa01494827d3ebf669b84f7bf2f 187 SUPERFAMILY SSF55729 6 179 1.54E-35 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_17805 f16aafa01494827d3ebf669b84f7bf2f 187 Pfam PF13302 Acetyltransferase (GNAT) domain 12 157 8.7E-20 T 01-11-2018 IPR000182 GNAT domain MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 SUPERFAMILY SSF50156 143 228 4.86E-11 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 SUPERFAMILY SSF50494 352 415 6.65E-7 T 01-11-2018 IPR009003 Peptidase S1, PA clan MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 SMART SM00228 116 192 4.7E-6 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 Pfam PF05580 SpoIVB peptidase S55 209 417 6.7E-85 T 01-11-2018 IPR008763 Peptidase S55, SpoIVB MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 Pfam PF13180 PDZ domain 141 197 1.7E-6 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 Gene3D G3DSA:2.30.42.10 139 218 1.8E-15 T 01-11-2018 MLA2C4_21830 bc6f22171ed007320c6bddab5139cb66 432 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 7 422 9.1E-182 T 01-11-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 Hamap MF_01491 Ribonuclease J [rnj]. 4 556 48.365 T 01-11-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 Gene3D G3DSA:3.40.50.10710 208 358 4.0E-185 T 01-11-2018 MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 Gene3D G3DSA:3.10.20.580 450 556 1.6E-37 T 01-11-2018 MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 363 408 3.0E-11 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 PIRSF PIRSF004803 1 556 1.3E-243 T 01-11-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 SMART SM00849 21 216 7.9E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 Gene3D G3DSA:3.60.15.10 12 443 4.0E-185 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.1E-14 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 SUPERFAMILY SSF56281 10 423 6.03E-98 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 554 9.1E-214 T 01-11-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 MLA2C4_19860 840770755a0abeecf5c0200796ffda9f 556 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 365 393 - T 01-11-2018 IPR001587 Ribonuclease J, conserved site MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 Gene3D G3DSA:3.30.870.10 41 229 9.3E-38 T 01-11-2018 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 Pfam PF13091 PLD-like domain 243 368 3.1E-26 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 Pfam PF13091 PLD-like domain 65 206 4.9E-10 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 SMART SM00155 146 173 3.3 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 SMART SM00155 316 343 3.1E-4 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 SUPERFAMILY SSF56024 43 215 5.23E-39 T 01-11-2018 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 SUPERFAMILY SSF56024 198 389 6.08E-38 T 01-11-2018 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 PIRSF PIRSF000850 32 113 0.099 T 01-11-2018 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 PIRSF PIRSF000850 294 399 2.4 T 01-11-2018 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 PIRSF PIRSF000850 208 290 0.043 T 01-11-2018 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 45 399 1.4E-91 T 01-11-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MLA2C4_09110 7302a91b7c5df95b383e6818f50c0a01 403 Gene3D G3DSA:3.30.870.10 230 381 9.2E-30 T 01-11-2018 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 Gene3D G3DSA:3.30.565.10 267 417 1.5E-36 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 Gene3D G3DSA:1.10.287.130 209 266 3.7E-15 T 01-11-2018 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 SUPERFAMILY SSF47384 197 270 3.92E-11 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 416 7.3E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 2.0E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 2.0E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 2.0E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.0E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 SUPERFAMILY SSF55874 262 417 4.85E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 SMART SM00388 206 272 2.3E-11 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 270 1.8E-10 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 SMART SM00387 313 417 2.2E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_18290 c504a534204b289696e043f58c919e6e 417 Pfam PF07694 5TMR of 5TMR-LYT 27 186 9.7E-9 T 01-11-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MLA2C4_00845 543b84560c6143b1e3eae894ee510d07 130 Gene3D G3DSA:3.30.230.10 4 130 1.5E-52 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_00845 543b84560c6143b1e3eae894ee510d07 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 01-11-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MLA2C4_00845 543b84560c6143b1e3eae894ee510d07 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.859 T 01-11-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MLA2C4_00845 543b84560c6143b1e3eae894ee510d07 130 SUPERFAMILY SSF54211 5 130 7.59E-50 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_00845 543b84560c6143b1e3eae894ee510d07 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.1E-46 T 01-11-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PRINTS PR00143 Citrate synthase signature 123 136 6.5E-41 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PRINTS PR00143 Citrate synthase signature 324 338 6.5E-41 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PRINTS PR00143 Citrate synthase signature 172 187 6.5E-41 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PRINTS PR00143 Citrate synthase signature 194 222 6.5E-41 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PRINTS PR00143 Citrate synthase signature 247 267 6.5E-41 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PRINTS PR00143 Citrate synthase signature 304 320 6.5E-41 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 Gene3D G3DSA:1.10.230.10 220 318 1.7E-124 T 01-11-2018 IPR016143 Citrate synthase-like, small alpha subdomain MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 PIRSF PIRSF001369 1 371 2.2E-151 T 01-11-2018 IPR024176 Citrate synthase, bacterial-type MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 5.7E-160 T 01-11-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 8.7E-127 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 Gene3D G3DSA:1.10.580.10 23 343 1.7E-124 T 01-11-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MLA2C4_23865 8d47354f4abceb944664bbfb14189e09 371 SUPERFAMILY SSF48256 2 371 1.83E-134 T 01-11-2018 IPR036969 Citrate synthase superfamily GO:0046912 MLA2C4_06800 f2d1d2bf6f6aeb0d34665f7113b730b5 189 SUPERFAMILY SSF51306 41 118 1.05E-10 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_06800 f2d1d2bf6f6aeb0d34665f7113b730b5 189 Pfam PF00717 Peptidase S24-like 47 102 1.3E-11 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_06800 f2d1d2bf6f6aeb0d34665f7113b730b5 189 Gene3D G3DSA:2.10.109.10 39 147 6.7E-6 T 01-11-2018 MLA2C4_06800 f2d1d2bf6f6aeb0d34665f7113b730b5 189 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 167 5.0E-59 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 MLA2C4_06800 f2d1d2bf6f6aeb0d34665f7113b730b5 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 105 116 8.9E-7 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 MLA2C4_06800 f2d1d2bf6f6aeb0d34665f7113b730b5 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 8.9E-7 T 01-11-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Pfam PF02151 UvrB/uvrC motif 196 229 5.3E-10 T 01-11-2018 IPR001943 UVR domain GO:0005515 MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.273 T 01-11-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Gene3D G3DSA:1.10.150.20 527 589 4.3E-20 T 01-11-2018 MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 570 6.0E-212 T 01-11-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Gene3D G3DSA:3.30.420.340 365 523 8.3E-62 T 01-11-2018 IPR038476 UvrC homology region 2 superfamily MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 SUPERFAMILY SSF82771 14 97 3.27E-22 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 SUPERFAMILY SSF47781 500 591 3.81E-21 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 SMART SM00465 15 95 1.1E-20 T 01-11-2018 IPR000305 GIY-YIG endonuclease MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 3.8E-54 T 01-11-2018 IPR001162 UvrC family homology region MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 SUPERFAMILY SSF46600 182 235 4.97E-14 T 01-11-2018 IPR036876 UVR domain superfamily MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Pfam PF01541 GIY-YIG catalytic domain 16 90 8.0E-10 T 01-11-2018 IPR000305 GIY-YIG endonuclease MLA2C4_23500 a44abddef1e4cda8a540796ce7de07ae 594 Gene3D G3DSA:3.40.1440.10 1 99 2.0E-37 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 SMART SM00382 277 471 2.3E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 SMART SM00382 27 223 9.2E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 Pfam PF00005 ABC transporter 18 169 6.6E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 SUPERFAMILY SSF52540 3 219 3.7E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 Gene3D G3DSA:3.40.50.300 251 488 1.6E-46 T 01-11-2018 MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 Gene3D G3DSA:3.40.50.300 1 234 2.8E-57 T 01-11-2018 MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 Pfam PF00005 ABC transporter 269 422 4.2E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03520 988a64415b094342030a1ecbdb58c66a 494 SUPERFAMILY SSF52540 267 473 3.63E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 Gene3D G3DSA:1.25.40.10 4 163 1.3E-16 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SUPERFAMILY SSF48452 202 406 2.47E-29 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SUPERFAMILY SSF48452 33 199 3.6E-16 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 Pfam PF13176 Tetratricopeptide repeat 174 201 1.0E-4 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 Pfam PF14559 Tetratricopeptide repeat 49 104 4.7E-6 T 01-11-2018 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 Pfam PF13429 Tetratricopeptide repeat 219 395 4.4E-9 T 01-11-2018 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 Gene3D G3DSA:1.25.40.10 170 419 1.2E-42 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SMART SM00028 271 304 9.4E-5 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SMART SM00028 339 372 18.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SMART SM00028 373 406 83.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SMART SM00028 237 270 7.2 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SMART SM00028 134 167 88.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_07990 121351008cb1eb6a006962672587aeb4 420 SMART SM00028 170 203 2.5 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 Pfam PF00171 Aldehyde dehydrogenase family 41 276 2.0E-12 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 SUPERFAMILY SSF53720 2 414 4.06E-113 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 42.134 T 01-11-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 Gene3D G3DSA:3.40.309.10 224 372 1.0E-163 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 Gene3D G3DSA:3.40.605.10 17 409 1.0E-163 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 343 - T 01-11-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 3.8E-168 T 01-11-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MLA2C4_15735 c2769d45e3a7558f3bd4c89821cfc6d2 415 PIRSF PIRSF000151 1 415 2.9E-179 T 01-11-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MLA2C4_25965 8c67a58ca5b30ea564013420b49ae10f 127 SUPERFAMILY SSF51230 3 125 2.36E-46 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_25965 8c67a58ca5b30ea564013420b49ae10f 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 9.7E-58 T 01-11-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MLA2C4_25965 8c67a58ca5b30ea564013420b49ae10f 127 Gene3D G3DSA:2.40.50.100 1 124 9.4E-53 T 01-11-2018 MLA2C4_25965 8c67a58ca5b30ea564013420b49ae10f 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 01-11-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MLA2C4_25965 8c67a58ca5b30ea564013420b49ae10f 127 Pfam PF01597 Glycine cleavage H-protein 7 126 2.1E-49 T 01-11-2018 IPR033753 Glycine cleavage system H-protein/Simiate MLA2C4_25965 8c67a58ca5b30ea564013420b49ae10f 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.698 T 01-11-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 80 396 5.6E-120 T 01-11-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 SUPERFAMILY SSF50156 98 220 2.5E-21 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 SUPERFAMILY SSF52096 64 396 1.7E-69 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Pfam PF01471 Putative peptidoglycan binding domain 415 468 2.5E-15 T 01-11-2018 IPR002477 Peptidoglycan binding-like MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Gene3D G3DSA:3.30.750.44 77 366 2.2E-90 T 01-11-2018 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Pfam PF03572 Peptidase family S41 228 390 4.8E-51 T 01-11-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 SMART SM00245 200 391 5.2E-66 T 01-11-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 SMART SM00228 127 198 1.2E-16 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Gene3D G3DSA:3.90.226.10 215 388 2.2E-90 T 01-11-2018 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Gene3D G3DSA:2.30.42.10 127 214 2.2E-90 T 01-11-2018 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 SUPERFAMILY SSF47090 400 470 1.07E-15 T 01-11-2018 IPR036365 PGBD-like superfamily MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Pfam PF13180 PDZ domain 128 198 4.4E-13 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_26810 24ea2650943cbaf28e70cf438faaed18 494 Gene3D G3DSA:1.10.101.10 396 479 9.6E-16 T 01-11-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 Gene3D G3DSA:3.30.390.10 6 116 3.3E-128 T 01-11-2018 IPR029017 Enolase-like, N-terminal MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 Gene3D G3DSA:3.20.20.120 117 344 3.3E-128 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 SUPERFAMILY SSF54826 2 126 2.57E-33 T 01-11-2018 MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 SUPERFAMILY SSF51604 114 361 1.31E-59 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 44.272 T 01-11-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 Pfam PF13378 Enolase C-terminal domain-like 145 343 8.3E-40 T 01-11-2018 IPR029065 Enolase C-terminal domain-like MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 12 332 5.5E-124 T 01-11-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 SMART SM00922 142 234 5.9E-20 T 01-11-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MLA2C4_25250 2825adf4975bf9156af82bf5dbc99070 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 125 6.7E-14 T 01-11-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MLA2C4_00340 955336f7a375f7e92e5ab61133fb8c61 161 Gene3D G3DSA:2.40.50.140 1 84 1.4E-29 T 01-11-2018 MLA2C4_00340 955336f7a375f7e92e5ab61133fb8c61 161 Pfam PF00575 S1 RNA binding domain 4 74 3.4E-22 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_00340 955336f7a375f7e92e5ab61133fb8c61 161 SMART SM00316 4 74 6.8E-27 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_00340 955336f7a375f7e92e5ab61133fb8c61 161 SUPERFAMILY SSF50249 4 81 1.39E-24 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-29 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-29 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-29 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.6E-29 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.6E-29 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-29 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 SUPERFAMILY SSF51735 2 243 3.48E-63 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 Gene3D G3DSA:3.40.50.720 1 252 3.0E-71 T 01-11-2018 MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 242 8.0E-49 T 01-11-2018 MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.2E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.2E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24030 f83195cad7d42461f30cda6c611a25d0 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.2E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_25275 82892b1ecc637a6d83bff9252f773dd1 464 SUPERFAMILY SSF56322 29 460 1.06E-104 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_25275 82892b1ecc637a6d83bff9252f773dd1 464 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 110 458 2.3E-105 T 01-11-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 MLA2C4_25275 82892b1ecc637a6d83bff9252f773dd1 464 Gene3D G3DSA:3.60.120.10 5 463 1.9E-105 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_25275 82892b1ecc637a6d83bff9252f773dd1 464 Pfam PF00425 chorismate binding enzyme 201 451 3.1E-73 T 01-11-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MLA2C4_22385 66b60b340ee9f0edf24485e783e5bf45 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 224 6.0E-66 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_22385 66b60b340ee9f0edf24485e783e5bf45 292 Gene3D G3DSA:3.30.70.120 202 277 6.7E-25 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_22385 66b60b340ee9f0edf24485e783e5bf45 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 230 284 4.9E-20 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_22385 66b60b340ee9f0edf24485e783e5bf45 292 PIRSF PIRSF006483 1 291 2.0E-89 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 SUPERFAMILY SSF53623 111 317 4.19E-49 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 SUPERFAMILY SSF53244 321 458 1.47E-34 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 Gene3D G3DSA:3.40.1190.10 92 318 2.6E-66 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 398 7.4E-15 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 SUPERFAMILY SSF63418 14 107 7.72E-21 T 01-11-2018 IPR035911 MurE/MurF, N-terminal MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 Gene3D G3DSA:3.40.1390.10 8 87 6.8E-21 T 01-11-2018 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 38 457 1.5E-131 T 01-11-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 Pfam PF08245 Mur ligase middle domain 116 299 6.3E-47 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 Gene3D G3DSA:3.90.190.20 319 470 2.8E-44 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_11015 74b2afbef61aaad02a8b55ad95f781b1 473 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 10 460 32.722 T 01-11-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_03130 7ec1adf35131f7a72561f9f993458d47 160 Pfam PF07849 Protein of unknown function (DUF1641) 121 155 2.4E-11 T 01-11-2018 IPR012440 Protein of unknown function DUF1641 MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 Pfam PF00733 Asparagine synthase 243 587 1.9E-93 T 01-11-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.0E-45 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 SUPERFAMILY SSF56235 1 226 1.0E-65 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 Gene3D G3DSA:3.60.20.10 2 184 3.3E-63 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 PIRSF PIRSF001589 1 615 1.1E-140 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 SUPERFAMILY SSF52402 231 576 1.13E-72 T 01-11-2018 MLA2C4_06065 34b00fb074f03fce89969a9faccd6d28 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 4.6E-167 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_14480 3b5231770109ac6b590b08369f37f782 199 SMART SM00014 61 166 4.2E-16 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_14480 3b5231770109ac6b590b08369f37f782 199 SUPERFAMILY SSF48317 3 169 1.83E-38 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_14480 3b5231770109ac6b590b08369f37f782 199 Pfam PF01569 PAP2 superfamily 63 172 1.2E-15 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_14480 3b5231770109ac6b590b08369f37f782 199 Gene3D G3DSA:1.20.144.10 80 189 1.1E-19 T 01-11-2018 MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 Pfam PF04542 Sigma-70 region 2 35 96 9.7E-11 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 Pfam PF08281 Sigma-70, region 4 122 170 2.9E-12 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 Gene3D G3DSA:1.10.1740.10 10 110 2.3E-20 T 01-11-2018 MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 28 174 4.5E-25 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 SUPERFAMILY SSF88946 14 111 1.57E-19 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 Gene3D G3DSA:1.10.10.10 112 176 9.4E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18625 feb18f36ebcd2d25de705d4f372b8129 177 SUPERFAMILY SSF88659 114 174 5.05E-15 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 SUPERFAMILY SSF117916 1 69 3.6E-8 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 Gene3D G3DSA:3.30.300.130 1 94 3.7E-6 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 Hamap MF_02040 Iron-sulfur cluster carrier protein. 99 347 33.945 T 01-11-2018 IPR019591 Mrp/NBP35 ATP-binding protein MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 Pfam PF01883 Iron-sulfur cluster assembly protein 4 57 8.5E-7 T 01-11-2018 IPR002744 MIP18 family-like MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 Gene3D G3DSA:3.40.50.300 95 324 3.0E-67 T 01-11-2018 MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 ProSitePatterns PS01215 Mrp family signature. 212 228 - T 01-11-2018 IPR000808 Mrp, conserved site GO:0005524 MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 SUPERFAMILY SSF52540 101 315 3.2E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00860 487a9fc14719941bfc887c00fbadf999 355 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 109 346 2.6E-84 T 01-11-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 Pfam PF04542 Sigma-70 region 2 2 68 1.5E-13 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 Gene3D G3DSA:1.10.10.10 95 158 1.3E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 Gene3D G3DSA:1.10.1740.10 1 94 2.6E-20 T 01-11-2018 MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 SUPERFAMILY SSF88659 89 157 8.04E-14 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 Pfam PF08281 Sigma-70, region 4 101 151 2.8E-14 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 155 8.3E-26 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_09070 b9823b43728d44a4f9eddbd1a61cffe5 162 SUPERFAMILY SSF88946 2 75 1.23E-17 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21285 d6055a9bbc028003de9b6bfb66166f13 152 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 9 147 2.4E-67 T 01-11-2018 IPR014203 Sporulation stage V, protein AC MLA2C4_21285 d6055a9bbc028003de9b6bfb66166f13 152 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 26 143 2.5E-41 T 01-11-2018 IPR005562 SpoVA MLA2C4_04450 8733d6e4659815ce202b6f520353dd22 201 Pfam PF09335 SNARE associated Golgi protein 29 154 2.2E-23 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_06975 29cdf4fbd912d835492f0ce0c6335d13 174 Pfam PF09602 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 1 164 1.4E-64 T 01-11-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP MLA2C4_06975 29cdf4fbd912d835492f0ce0c6335d13 174 TIGRFAM TIGR02131 phaP_Bmeg: polyhydroxyalkanoic acid inclusion protein PhaP 1 164 5.0E-80 T 01-11-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 Gene3D G3DSA:3.40.50.1370 6 287 1.6E-102 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 287 1.9E-21 T 01-11-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 Gene3D G3DSA:3.40.50.1370 127 270 1.6E-102 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 SUPERFAMILY SSF53671 1 292 4.19E-91 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 289 6.8E-99 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 2.2E-32 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 2.2E-32 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 2.2E-32 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 272 286 2.2E-32 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 2.2E-32 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00101 Aspartate carbamoyltransferase signature 248 253 2.2E-32 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 139 7.6E-41 T 01-11-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 293 40.202 T 01-11-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 9.0E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 9.0E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 279 9.0E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_20330 d2623880a9b947bce7fe54fb7fdcd75a 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 244 253 9.0E-23 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 566 1.5E-224 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 SUPERFAMILY SSF50677 196 347 1.7E-64 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 880 16.251 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Pfam PF08264 Anticodon-binding domain of tRNA 609 755 2.2E-45 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Gene3D G3DSA:1.10.287.380 808 880 5.6E-23 T 01-11-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Gene3D G3DSA:1.10.730.10 8 743 0.0 T 01-11-2018 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 815 879 8.4E-25 T 01-11-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 PRINTS PR00986 Valyl-tRNA synthetase signature 446 467 2.2E-38 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 2.2E-38 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 2.2E-38 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 2.2E-38 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 PRINTS PR00986 Valyl-tRNA synthetase signature 478 496 2.2E-38 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Gene3D G3DSA:3.40.50.620 28 527 0.0 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 862 0.0 T 01-11-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 Gene3D G3DSA:3.90.740.10 181 347 0.0 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 SUPERFAMILY SSF46589 815 879 6.28E-17 T 01-11-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 SUPERFAMILY SSF47323 577 829 2.06E-78 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23240 f0997017a5e85a086594e4e05dcae398 881 SUPERFAMILY SSF52374 6 576 6.93E-146 T 01-11-2018 MLA2C4_17200 7253efd48d75fdf736fcb564703ec137 235 SUPERFAMILY SSF48371 2 235 3.74E-69 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_17200 7253efd48d75fdf736fcb564703ec137 235 Pfam PF08713 DNA alkylation repair enzyme 6 213 2.8E-22 T 01-11-2018 IPR014825 DNA alkylation repair enzyme MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 SUPERFAMILY SSF52540 71 358 2.23E-75 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Gene3D G3DSA:3.30.70.330 406 481 9.0E-29 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Gene3D G3DSA:3.40.50.300 209 368 9.8E-53 T 01-11-2018 MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Pfam PF00270 DEAD/DEAH box helicase 28 194 1.3E-48 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 6 480 76.425 T 01-11-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 01-11-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 SMART SM00487 23 220 2.1E-57 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Gene3D G3DSA:3.40.50.300 1 208 8.3E-73 T 01-11-2018 MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 SMART SM00490 256 337 1.8E-35 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Pfam PF03880 DbpA RNA binding domain 407 477 3.7E-20 T 01-11-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MLA2C4_28280 5d203a3f284adb9aa07d46d877be1008 481 Pfam PF00271 Helicase conserved C-terminal domain 229 337 6.3E-30 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_11095 b47f1d9177b08ea4467751931274e4f1 301 SUPERFAMILY SSF53474 9 301 4.15E-50 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_11095 b47f1d9177b08ea4467751931274e4f1 301 Pfam PF00561 alpha/beta hydrolase fold 29 288 2.9E-25 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_11095 b47f1d9177b08ea4467751931274e4f1 301 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 59 70 9.4E-10 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_11095 b47f1d9177b08ea4467751931274e4f1 301 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 102 116 9.4E-10 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_11095 b47f1d9177b08ea4467751931274e4f1 301 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 31 39 9.4E-10 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_11095 b47f1d9177b08ea4467751931274e4f1 301 Gene3D G3DSA:3.40.50.1820 6 301 1.3E-51 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_10160 d2c799d21b460b1f10611e691674d712 153 Pfam PF00293 NUDIX domain 22 143 4.2E-21 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_10160 d2c799d21b460b1f10611e691674d712 153 PRINTS PR00502 NUDIX hydrolase family signature 58 73 6.1E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_10160 d2c799d21b460b1f10611e691674d712 153 PRINTS PR00502 NUDIX hydrolase family signature 44 58 6.1E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_10160 d2c799d21b460b1f10611e691674d712 153 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_10160 d2c799d21b460b1f10611e691674d712 153 SUPERFAMILY SSF55811 5 147 4.6E-32 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_10160 d2c799d21b460b1f10611e691674d712 153 Gene3D G3DSA:3.90.79.10 1 147 6.2E-37 T 01-11-2018 MLA2C4_21000 45a1eae77f132098d30434ac6393c43c 169 Gene3D G3DSA:3.40.50.720 6 142 5.0E-27 T 01-11-2018 MLA2C4_21000 45a1eae77f132098d30434ac6393c43c 169 SUPERFAMILY SSF51735 10 120 3.18E-27 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21000 45a1eae77f132098d30434ac6393c43c 169 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 9.7E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21000 45a1eae77f132098d30434ac6393c43c 169 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 9.7E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21000 45a1eae77f132098d30434ac6393c43c 169 Pfam PF00106 short chain dehydrogenase 17 116 8.2E-22 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_08745 4c9ef87d8d4ad861eb34b4a784cabb10 278 Gene3D G3DSA:1.10.10.10 1 101 9.5E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08745 4c9ef87d8d4ad861eb34b4a784cabb10 278 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 1.4E-23 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal MLA2C4_08745 4c9ef87d8d4ad861eb34b4a784cabb10 278 SUPERFAMILY SSF46785 2 97 9.24E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08745 4c9ef87d8d4ad861eb34b4a784cabb10 278 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 227 4.9E-8 T 01-11-2018 IPR021586 Transcription regulator TrmB, C-terminal MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Gene3D G3DSA:1.10.3810.10 94 287 9.3E-202 T 01-11-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Gene3D G3DSA:3.40.710.10 326 654 9.3E-202 T 01-11-2018 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 SMART SM00060 678 752 8.0E-8 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 SUPERFAMILY SSF53955 73 285 2.31E-73 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 SUPERFAMILY SSF49265 679 765 6.97E-12 T 01-11-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Pfam PF00912 Transglycosylase 84 260 6.5E-65 T 01-11-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 SUPERFAMILY SSF56601 245 659 1.59E-100 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 643 9.2E-172 T 01-11-2018 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 634 2.9E-39 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Pfam PF00041 Fibronectin type III domain 679 753 4.4E-10 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Gene3D G3DSA:2.60.40.10 672 763 3.3E-13 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_08145 bc73e9717a7dfeabd4c9f2e15228d1f6 895 Gene3D G3DSA:3.90.1310.20 80 537 9.3E-202 T 01-11-2018 MLA2C4_15720 69871d64384a9f809612e9e5d6973f22 406 Gene3D G3DSA:1.20.1250.20 4 389 1.1E-41 T 01-11-2018 MLA2C4_15720 69871d64384a9f809612e9e5d6973f22 406 SUPERFAMILY SSF103473 2 392 2.22E-49 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_15720 69871d64384a9f809612e9e5d6973f22 406 Pfam PF07690 Major Facilitator Superfamily 33 346 5.5E-34 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_11340 13229b8c888734deb0ac540bc14e0493 300 SUPERFAMILY SSF161098 79 275 7.19E-9 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_11340 13229b8c888734deb0ac540bc14e0493 300 Gene3D G3DSA:1.10.3720.10 76 296 5.3E-8 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_11340 13229b8c888734deb0ac540bc14e0493 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 291 4.0E-11 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_22410 904d8644d0dcc06c23151ccc217ef154 316 Gene3D G3DSA:3.40.1010.20 104 197 8.7E-95 T 01-11-2018 MLA2C4_22410 904d8644d0dcc06c23151ccc217ef154 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 1.5E-91 T 01-11-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MLA2C4_22410 904d8644d0dcc06c23151ccc217ef154 316 Gene3D G3DSA:3.40.1010.20 7 284 8.7E-95 T 01-11-2018 MLA2C4_22410 904d8644d0dcc06c23151ccc217ef154 316 Gene3D G3DSA:3.40.50.11270 12 103 8.7E-95 T 01-11-2018 MLA2C4_22410 904d8644d0dcc06c23151ccc217ef154 316 Pfam PF02401 LytB protein 4 284 8.4E-81 T 01-11-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MLA2C4_22410 904d8644d0dcc06c23151ccc217ef154 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 31.877 T 01-11-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MLA2C4_04330 90ec49752eb2055d1381b49b7fd6eddc 400 SUPERFAMILY SSF103473 13 389 3.53E-63 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_04330 90ec49752eb2055d1381b49b7fd6eddc 400 Pfam PF07690 Major Facilitator Superfamily 20 238 9.2E-26 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_04330 90ec49752eb2055d1381b49b7fd6eddc 400 Gene3D G3DSA:1.20.1250.20 10 388 2.5E-57 T 01-11-2018 MLA2C4_04330 90ec49752eb2055d1381b49b7fd6eddc 400 Pfam PF03209 PUCC protein 279 395 1.4E-4 T 01-11-2018 IPR004896 PucC-related MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 122 1.5E-34 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 Gene3D G3DSA:3.30.360.10 130 326 5.5E-145 T 01-11-2018 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 SUPERFAMILY SSF51735 7 158 2.35E-51 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 SMART SM00859 8 123 2.1E-44 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 Gene3D G3DSA:3.40.50.720 9 340 5.5E-145 T 01-11-2018 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 PIRSF PIRSF000148 6 348 9.6E-131 T 01-11-2018 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 343 38.598 T 01-11-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 344 3.2E-161 T 01-11-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 01-11-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 SUPERFAMILY SSF55347 131 330 3.57E-75 T 01-11-2018 MLA2C4_19875 1c46da9bbf53b9b874ba72412e3c95eb 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 329 1.3E-58 T 01-11-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 449 6.6E-62 T 01-11-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 476 570 2.5E-12 T 01-11-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 SUPERFAMILY SSF52518 196 458 3.67E-73 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 SUPERFAMILY SSF53323 1 221 4.32E-46 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 SUPERFAMILY SSF52922 468 576 9.82E-25 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 Gene3D G3DSA:3.40.50.970 186 386 3.0E-76 T 01-11-2018 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 Gene3D G3DSA:3.40.50.920 466 579 8.3E-31 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 4.2E-41 T 01-11-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 574 7.1E-214 T 01-11-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 MLA2C4_19735 1626ec0b62592e6645c45a41ff382aab 585 Gene3D G3DSA:3.40.920.10 1 185 2.0E-27 T 01-11-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MLA2C4_12415 b0d49fc4e53d4d98ef53ba9d3db8ac51 295 Pfam PF00892 EamA-like transporter family 8 139 1.1E-20 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_12415 b0d49fc4e53d4d98ef53ba9d3db8ac51 295 Pfam PF00892 EamA-like transporter family 152 286 1.1E-16 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_12415 b0d49fc4e53d4d98ef53ba9d3db8ac51 295 SUPERFAMILY SSF103481 38 143 1.44E-18 T 01-11-2018 MLA2C4_12415 b0d49fc4e53d4d98ef53ba9d3db8ac51 295 SUPERFAMILY SSF103481 191 289 1.03E-11 T 01-11-2018 MLA2C4_19460 24aad538333c2c65e3748f6dd387dd13 297 Gene3D G3DSA:3.60.21.10 64 266 3.6E-25 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_19460 24aad538333c2c65e3748f6dd387dd13 297 SUPERFAMILY SSF56300 60 294 4.92E-37 T 01-11-2018 MLA2C4_19460 24aad538333c2c65e3748f6dd387dd13 297 Pfam PF00149 Calcineurin-like phosphoesterase 64 229 5.5E-12 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 Gene3D G3DSA:3.30.470.20 1 234 3.9E-97 T 01-11-2018 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 3.8E-165 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 PIRSF PIRSF001554 1 386 2.7E-156 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 Pfam PF08442 ATP-grasp domain 2 202 2.2E-83 T 01-11-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 SUPERFAMILY SSF52210 240 385 5.49E-55 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 Gene3D G3DSA:3.30.1490.20 21 104 3.9E-97 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 Pfam PF00549 CoA-ligase 262 381 1.3E-26 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 SUPERFAMILY SSF56059 1 238 4.52E-85 T 01-11-2018 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 Gene3D G3DSA:3.40.50.261 240 386 2.9E-57 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MLA2C4_20050 a9af7b9174b99e12253364c9b638e531 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.748 T 01-11-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.30.559.30 207 435 4.4E-60 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.40.50.12780 1512 1931 1.9E-147 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.40.50.12780 451 858 7.3E-134 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF52777 1058 1230 1.89E-44 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 947 2.2E-11 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF13193 AMP-binding enzyme C-terminal domain 1945 2020 2.3E-13 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF52777 11 184 2.45E-32 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF52777 190 427 3.78E-34 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF52777 1244 1497 9.0E-59 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00668 Condensation domain 10 444 4.3E-69 T 01-11-2018 IPR001242 Condensation domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00668 Condensation domain 1055 1503 1.5E-98 T 01-11-2018 IPR001242 Condensation domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1546 1961 4.7E-140 T 01-11-2018 IPR010071 Amino acid adenylation domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 888 4.0E-132 T 01-11-2018 IPR010071 Amino acid adenylation domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF47336 2040 2110 4.97E-20 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF56801 1484 2058 3.27E-167 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:1.10.1200.10 962 1044 1.1E-24 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.30.300.30 1932 2034 8.2E-37 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.30.300.30 859 961 1.4E-35 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00501 AMP-binding enzyme 1525 1937 2.9E-108 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00501 AMP-binding enzyme 465 864 2.1E-103 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF53474 2113 2376 2.65E-57 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.40.50.1820 2035 2378 1.6E-113 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF56801 428 985 4.58E-154 T 01-11-2018 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00550 Phosphopantetheine attachment site 2048 2110 3.1E-14 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00550 Phosphopantetheine attachment site 975 1036 3.6E-14 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.30.559.10 11 206 5.5E-54 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SMART SM00823 Phosphopantetheine attachment site 972 1041 1.8E-4 T 01-11-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SMART SM00823 Phosphopantetheine attachment site 2048 2114 2.7E-5 T 01-11-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.30.559.10 1057 1429 9.6E-144 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Pfam PF00975 Thioesterase domain 2133 2304 1.9E-30 T 01-11-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SUPERFAMILY SSF47336 967 1038 1.06E-18 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 SMART SM00824 Thioesterase 2135 2376 7.9E-4 T 01-11-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 MLA2C4_12210 1e7dbd67f5ed42cacd1f9d6fc0c16396 2385 Gene3D G3DSA:3.30.559.30 1234 1491 9.6E-144 T 01-11-2018 MLA2C4_05795 916d08489e3ee290df0d0c94d9ae0ce2 244 SUPERFAMILY SSF56281 1 242 1.24E-56 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_05795 916d08489e3ee290df0d0c94d9ae0ce2 244 Gene3D G3DSA:3.60.15.10 1 244 3.4E-102 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_05795 916d08489e3ee290df0d0c94d9ae0ce2 244 SMART SM00849 18 211 3.3E-11 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_05795 916d08489e3ee290df0d0c94d9ae0ce2 244 Pfam PF12706 Beta-lactamase superfamily domain 30 211 1.5E-21 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 SMART SM00861 590 786 1.2E-42 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 SUPERFAMILY SSF52518 572 791 5.99E-43 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 SUPERFAMILY SSF52518 152 521 9.16E-72 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 935 0.0 T 01-11-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Gene3D G3DSA:3.40.50.12470 548 808 7.2E-150 T 01-11-2018 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Pfam PF00676 Dehydrogenase E1 component 223 522 1.3E-63 T 01-11-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Gene3D G3DSA:3.40.50.11610 726 935 7.2E-150 T 01-11-2018 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 PIRSF PIRSF000157 1 939 0.0 T 01-11-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Gene3D G3DSA:3.40.50.970 155 528 4.2E-135 T 01-11-2018 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 1 939 23.39 T 01-11-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 791 937 5.5E-37 T 01-11-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MLA2C4_06595 25cad0d504e1246df408300a398635b5 955 Pfam PF02779 Transketolase, pyrimidine binding domain 589 787 1.1E-54 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_22645 d37cfa8f0fbd67fef86f67a9d5f962ac 51 Pfam PF08970 Sporulation inhibitor A 6 47 2.1E-18 T 01-11-2018 IPR015064 Sporulation inhibitor A MLA2C4_22645 d37cfa8f0fbd67fef86f67a9d5f962ac 51 SUPERFAMILY SSF100985 6 49 3.92E-16 T 01-11-2018 IPR036916 Sporulation inhibitor A superfamily MLA2C4_22645 d37cfa8f0fbd67fef86f67a9d5f962ac 51 Gene3D G3DSA:1.10.287.1100 9 42 2.4E-15 T 01-11-2018 IPR036916 Sporulation inhibitor A superfamily MLA2C4_17395 97184b59f29cf88f1d26a8931efd14ae 283 Gene3D G3DSA:3.40.50.300 2 56 2.7E-5 T 01-11-2018 MLA2C4_17395 97184b59f29cf88f1d26a8931efd14ae 283 SUPERFAMILY SSF52540 4 205 3.22E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25775 9ad510296ee17e3bc517b32ccbfa09ac 163 Pfam PF04608 Phosphatidylglycerophosphatase A 13 156 2.4E-21 T 01-11-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MLA2C4_25775 9ad510296ee17e3bc517b32ccbfa09ac 163 SUPERFAMILY SSF101307 7 159 4.05E-58 T 01-11-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 MLA2C4_25775 9ad510296ee17e3bc517b32ccbfa09ac 163 PIRSF PIRSF019587 2 163 3.3E-77 T 01-11-2018 IPR026038 Putative phosphatidylglycerophosphatase MLA2C4_25775 9ad510296ee17e3bc517b32ccbfa09ac 163 Gene3D G3DSA:1.10.3760.10 1 163 6.8E-75 T 01-11-2018 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 Gene3D G3DSA:3.40.50.620 11 242 1.8E-70 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 9 324 25.202 T 01-11-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 388 433 2.3E-20 T 01-11-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 SUPERFAMILY SSF56037 339 452 1.28E-18 T 01-11-2018 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 Pfam PF01171 PP-loop family 25 208 4.6E-58 T 01-11-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 SUPERFAMILY SSF82829 220 328 5.49E-10 T 01-11-2018 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 SUPERFAMILY SSF52402 12 242 6.29E-59 T 01-11-2018 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 25 212 7.8E-59 T 01-11-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 SMART SM00977 388 460 5.2E-24 T 01-11-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 Pfam PF09179 TilS substrate binding domain 261 329 2.0E-7 T 01-11-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 Gene3D G3DSA:1.20.59.30 249 336 1.6E-30 T 01-11-2018 MLA2C4_00360 c197c56292112e2623a580965b3019ee 476 Pfam PF11734 TilS substrate C-terminal domain 388 451 7.8E-15 T 01-11-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.2E-5 T 01-11-2018 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 1.2E-5 T 01-11-2018 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Gene3D G3DSA:1.10.150.570 568 620 1.2E-22 T 01-11-2018 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Gene3D G3DSA:1.10.10.1800 459 549 2.0E-26 T 01-11-2018 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 SUPERFAMILY SSF51905 7 261 1.24E-44 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 4.0E-295 T 01-11-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 01-11-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 SMART SM01228 545 616 1.8E-42 T 01-11-2018 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.561 T 01-11-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 01-11-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Gene3D G3DSA:3.50.50.60 296 458 1.2E-56 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Gene3D G3DSA:3.50.50.60 2 224 9.2E-84 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Pfam PF13932 GidA associated domain 401 615 6.0E-79 T 01-11-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 MLA2C4_28455 4a83c757c70ccfc7201840f7cb601898 629 Pfam PF01134 Glucose inhibited division protein A 9 398 1.4E-172 T 01-11-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MLA2C4_18660 74c62c90a62acf229311adad07d2dd8d 410 Gene3D G3DSA:1.10.150.130 41 155 8.9E-11 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_18660 74c62c90a62acf229311adad07d2dd8d 410 Gene3D G3DSA:1.10.443.10 188 408 3.0E-37 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_18660 74c62c90a62acf229311adad07d2dd8d 410 SUPERFAMILY SSF56349 45 391 2.94E-33 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_18660 74c62c90a62acf229311adad07d2dd8d 410 Pfam PF00589 Phage integrase family 196 384 3.3E-22 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 SMART SM01086 774 863 2.8E-35 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 339 1.1E-13 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 SUPERFAMILY SSF81923 4 158 1.08E-40 T 01-11-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 SUPERFAMILY SSF52540 160 551 2.33E-96 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 SMART SM00382 201 347 1.9E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 SMART SM00382 603 754 4.0E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 854 2.6E-24 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Gene3D G3DSA:3.40.50.300 346 550 3.8E-71 T 01-11-2018 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 148 5.1E-11 T 01-11-2018 IPR004176 Clp, N-terminal MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.3E-14 T 01-11-2018 IPR004176 Clp, N-terminal MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 2.0E-42 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 2.0E-42 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 2.0E-42 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 2.0E-42 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 01-11-2018 IPR028299 ClpA/B, conserved site 2 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Gene3D G3DSA:3.40.50.300 556 772 3.7E-88 T 01-11-2018 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 01-11-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 01-11-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Gene3D G3DSA:1.10.8.60 774 866 9.6E-29 T 01-11-2018 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 SUPERFAMILY SSF52540 552 864 1.76E-83 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Gene3D G3DSA:1.10.1780.10 1 151 2.4E-35 T 01-11-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 602 768 3.9E-57 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_06155 65e6fd7fde7f8d89090eaf966d8835d9 866 Gene3D G3DSA:3.40.50.300 152 345 7.1E-75 T 01-11-2018 MLA2C4_09745 4eb1cfad605375e536a60de21a493a2a 216 Pfam PF01323 DSBA-like thioredoxin domain 6 193 3.0E-30 T 01-11-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MLA2C4_09745 4eb1cfad605375e536a60de21a493a2a 216 SUPERFAMILY SSF52833 1 200 2.37E-35 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_09745 4eb1cfad605375e536a60de21a493a2a 216 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 01-11-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 MLA2C4_09745 4eb1cfad605375e536a60de21a493a2a 216 Gene3D G3DSA:3.40.30.10 1 196 2.7E-39 T 01-11-2018 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 01-11-2018 IPR018215 ClpP, Ser active site MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 5.8E-107 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 Pfam PF00574 Clp protease 13 192 4.6E-87 T 01-11-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.6E-54 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.6E-54 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.6E-54 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.6E-54 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.6E-54 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 SUPERFAMILY SSF52096 10 192 7.02E-74 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.238 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 Gene3D G3DSA:3.90.226.10 1 193 6.1E-84 T 01-11-2018 MLA2C4_26645 b81d37ad1baf6afe8a68d4582d88540c 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 01-11-2018 IPR033135 ClpP, histidine active site MLA2C4_06520 7a18e712e0d28deb77b26f703b089295 258 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 11 255 33.481 T 01-11-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_06520 7a18e712e0d28deb77b26f703b089295 258 Gene3D G3DSA:3.20.20.70 3 257 2.3E-94 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_06520 7a18e712e0d28deb77b26f703b089295 258 SUPERFAMILY SSF51366 6 252 9.42E-85 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_06520 7a18e712e0d28deb77b26f703b089295 258 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 01-11-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_06520 7a18e712e0d28deb77b26f703b089295 258 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 11 248 3.8E-77 T 01-11-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_06520 7a18e712e0d28deb77b26f703b089295 258 Pfam PF00290 Tryptophan synthase alpha chain 10 255 1.3E-89 T 01-11-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 Pfam PF01668 SmpB protein 9 150 1.3E-64 T 01-11-2018 IPR000037 SsrA-binding protein GO:0003723 MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 Gene3D G3DSA:2.40.280.10 3 129 4.7E-53 T 01-11-2018 IPR023620 Small protein B MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 01-11-2018 IPR020081 SsrA-binding protein, conserved site MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 77.963 T 01-11-2018 IPR000037 SsrA-binding protein GO:0003723 MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 SUPERFAMILY SSF74982 3 132 6.8E-55 T 01-11-2018 IPR023620 Small protein B MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 149 6.4E-62 T 01-11-2018 IPR000037 SsrA-binding protein GO:0003723 MLA2C4_26530 d42f758ae786f43024c4183bdffb2eec 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 7.0E-53 T 01-11-2018 IPR000037 SsrA-binding protein GO:0003723 MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 2.3E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 2.3E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 2.3E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 325 2.3E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 Gene3D G3DSA:1.10.287.130 121 168 3.0E-32 T 01-11-2018 MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 322 3.4E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 Gene3D G3DSA:3.30.565.10 169 323 3.0E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 SMART SM00387 216 327 8.1E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_13815 0e66a5d580a7be98d9ce417c7d337a6e 327 SUPERFAMILY SSF55874 163 324 6.42E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 PIRSF PIRSF005261 1 291 7.2E-76 T 01-11-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 291 40.629 T 01-11-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 SUPERFAMILY SSF64397 2 241 3.92E-79 T 01-11-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 Pfam PF01430 Hsp33 protein 3 280 5.2E-90 T 01-11-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 SUPERFAMILY SSF118352 232 290 2.09E-19 T 01-11-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 Gene3D G3DSA:3.55.30.10 2 233 2.7E-90 T 01-11-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MLA2C4_00380 f89674156308d94aa8a0f4f50f406652 291 Gene3D G3DSA:3.90.1280.10 234 290 1.8E-22 T 01-11-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 SUPERFAMILY SSF52540 3 236 7.74E-54 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 Pfam PF00005 ABC transporter 23 172 7.7E-26 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 Pfam PF00005 ABC transporter 316 462 2.2E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 Pfam PF12558 ATP-binding cassette cobalt transporter 236 307 4.3E-13 T 01-11-2018 IPR022216 Putative ABC cobalt transporter MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 Gene3D G3DSA:3.40.50.300 296 542 3.8E-64 T 01-11-2018 MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 Gene3D G3DSA:3.40.50.300 2 250 4.1E-63 T 01-11-2018 MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 SMART SM00382 31 223 1.5E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 SMART SM00382 325 510 2.7E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_14100 033995f936f772b8d143b3a13fdb5b63 566 SUPERFAMILY SSF52540 286 527 2.72E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 Pfam PF01022 Bacterial regulatory protein, arsR family 48 93 1.1E-16 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 SUPERFAMILY SSF46785 29 122 5.23E-29 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.4E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 1.4E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 73 1.4E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.4E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 SMART SM00418 41 119 8.8E-31 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 64 82 - T 01-11-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 MLA2C4_03150 ae34a8ecad993342a26dc6d8e91c773d 125 Gene3D G3DSA:1.10.10.10 9 125 4.1E-39 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03380 bb856c42596d909ea5134ad315e9afb7 243 SMART SM00382 27 214 3.5E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_03380 bb856c42596d909ea5134ad315e9afb7 243 SUPERFAMILY SSF52540 2 235 2.73E-82 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03380 bb856c42596d909ea5134ad315e9afb7 243 PIRSF PIRSF039085 1 242 3.0E-115 T 01-11-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MLA2C4_03380 bb856c42596d909ea5134ad315e9afb7 243 Gene3D G3DSA:3.40.50.300 1 242 1.2E-78 T 01-11-2018 MLA2C4_03380 bb856c42596d909ea5134ad315e9afb7 243 Pfam PF00005 ABC transporter 18 166 1.6E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03380 bb856c42596d909ea5134ad315e9afb7 243 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_23800 252d43aca23c47c20b2300a2898b168d 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 3.0E-42 T 01-11-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MLA2C4_23800 252d43aca23c47c20b2300a2898b168d 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 32.254 T 01-11-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MLA2C4_23800 252d43aca23c47c20b2300a2898b168d 130 Gene3D G3DSA:3.30.360.110 4 65 8.4E-26 T 01-11-2018 MLA2C4_23800 252d43aca23c47c20b2300a2898b168d 130 SUPERFAMILY SSF56276 6 117 8.83E-42 T 01-11-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 MLA2C4_23800 252d43aca23c47c20b2300a2898b168d 130 Gene3D G3DSA:3.30.160.750 66 129 1.0E-19 T 01-11-2018 MLA2C4_23800 252d43aca23c47c20b2300a2898b168d 130 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 7.7E-37 T 01-11-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Gene3D G3DSA:1.20.1270.90 664 744 1.3E-9 T 01-11-2018 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Gene3D G3DSA:2.60.40.10 342 440 9.1E-9 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Gene3D G3DSA:2.60.120.200 441 656 4.3E-25 T 01-11-2018 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Pfam PF00149 Calcineurin-like phosphoesterase 52 243 6.6E-13 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 SUPERFAMILY SSF49265 345 432 3.32E-7 T 01-11-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 504 649 3.4E-17 T 01-11-2018 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Pfam PF07554 FIVAR domain 687 734 0.01 T 01-11-2018 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Pfam PF07554 FIVAR domain 748 811 0.011 T 01-11-2018 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 Gene3D G3DSA:3.60.21.10 28 311 3.4E-34 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_04470 59f321843ec376898efe555d784fed03 819 SUPERFAMILY SSF56300 47 310 2.53E-36 T 01-11-2018 MLA2C4_04470 59f321843ec376898efe555d784fed03 819 SUPERFAMILY SSF49899 452 654 6.76E-28 T 01-11-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MLA2C4_11245 3f0f6da4dd57d2945164f4057d315ccf 324 SUPERFAMILY SSF56281 54 277 1.3E-36 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_11245 3f0f6da4dd57d2945164f4057d315ccf 324 Gene3D G3DSA:3.60.15.10 29 320 4.0E-83 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_11245 3f0f6da4dd57d2945164f4057d315ccf 324 Pfam PF12706 Beta-lactamase superfamily domain 74 264 3.2E-41 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_11245 3f0f6da4dd57d2945164f4057d315ccf 324 PIRSF PIRSF038896 1 308 8.7E-94 T 01-11-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 Gene3D G3DSA:1.10.8.500 184 233 7.9E-13 T 01-11-2018 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 Gene3D G3DSA:1.10.287.130 234 301 6.9E-20 T 01-11-2018 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 SUPERFAMILY SSF47384 221 303 2.35E-17 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 7.3E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 SUPERFAMILY SSF55874 294 458 3.8E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_17035 585506840775706a3415a87171ad4a48 458 SMART SM00388 238 304 3.9E-17 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 SMART SM00387 348 458 9.6E-36 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_17035 585506840775706a3415a87171ad4a48 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 1.4E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.4E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.4E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.4E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 SUPERFAMILY SSF158472 186 235 1.19E-11 T 01-11-2018 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 SMART SM00304 185 237 5.2E-12 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_17035 585506840775706a3415a87171ad4a48 458 Gene3D G3DSA:3.30.565.10 302 458 5.2E-45 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_17035 585506840775706a3415a87171ad4a48 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 457 1.3E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_17035 585506840775706a3415a87171ad4a48 458 Pfam PF00672 HAMP domain 186 233 1.3E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_06390 c6fd914ad6a448a996e74ac19b01f5b1 284 SUPERFAMILY SSF51735 4 278 2.14E-90 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_06390 c6fd914ad6a448a996e74ac19b01f5b1 284 Gene3D G3DSA:3.90.25.10 161 274 1.6E-114 T 01-11-2018 MLA2C4_06390 c6fd914ad6a448a996e74ac19b01f5b1 284 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 278 6.7E-101 T 01-11-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MLA2C4_06390 c6fd914ad6a448a996e74ac19b01f5b1 284 Pfam PF04321 RmlD substrate binding domain 4 280 1.7E-101 T 01-11-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MLA2C4_06390 c6fd914ad6a448a996e74ac19b01f5b1 284 Gene3D G3DSA:3.40.50.720 5 268 1.6E-114 T 01-11-2018 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 Gene3D G3DSA:3.30.470.130 1 450 5.1E-202 T 01-11-2018 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.8E-82 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 7.5E-45 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 SUPERFAMILY SSF52440 1 113 2.59E-51 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 SUPERFAMILY SSF51246 332 445 1.73E-48 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 SUPERFAMILY SSF56059 83 349 7.07E-67 T 01-11-2018 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.0E-47 T 01-11-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 SMART SM00878 337 443 2.6E-72 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_21885 197a91560dce87f42bec93b3c9f8879e 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 2.4E-241 T 01-11-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Gene3D G3DSA:2.40.50.140 633 720 1.6E-25 T 01-11-2018 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Gene3D G3DSA:3.30.420.140 321 447 2.5E-155 T 01-11-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Pfam PF12836 Helix-hairpin-helix motif 487 551 3.1E-26 T 01-11-2018 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SUPERFAMILY SSF47781 557 631 3.33E-14 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SUPERFAMILY SSF158832 9 317 5.75E-116 T 01-11-2018 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SMART SM00316 648 719 9.2E-22 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SMART SM00732 322 420 3.7E-32 T 01-11-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Gene3D G3DSA:1.10.3500.10 117 494 2.5E-155 T 01-11-2018 IPR023323 Tex-like domain superfamily MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Gene3D G3DSA:1.10.10.650 4 114 9.3E-37 T 01-11-2018 IPR023319 Tex-like protein, HTH domain superfamily MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Pfam PF16921 Tex protein YqgF-like domain 322 447 5.2E-56 T 01-11-2018 IPR032639 Tex protein, YqgF-like domain MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Pfam PF09371 Tex-like protein N-terminal domain 15 197 2.4E-70 T 01-11-2018 IPR018974 Tex-like protein, N-terminal MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SUPERFAMILY SSF50249 634 720 1.12E-23 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SUPERFAMILY SSF47781 466 552 2.45E-26 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Gene3D G3DSA:1.10.150.310 495 629 1.7E-44 T 01-11-2018 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 Pfam PF00575 S1 RNA binding domain 648 718 6.0E-16 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_01430 e147652c0c4fc36260606467d71f62cc 722 SUPERFAMILY SSF53098 318 465 3.03E-49 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 148 6.0E-16 T 01-11-2018 IPR000014 PAS domain MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 280 3.3E-10 T 01-11-2018 IPR000014 PAS domain MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Gene3D G3DSA:1.10.287.130 278 353 3.2E-18 T 01-11-2018 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SMART SM00388 290 354 2.1E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SMART SM00387 396 503 2.5E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SMART SM00091 156 221 1.4 T 01-11-2018 IPR000014 PAS domain MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SMART SM00091 32 98 4.6E-11 T 01-11-2018 IPR000014 PAS domain MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SUPERFAMILY SSF55785 20 137 6.28E-15 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 397 502 1.0E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SUPERFAMILY SSF55874 348 501 1.96E-38 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Pfam PF13426 PAS domain 42 137 2.3E-7 T 01-11-2018 IPR000014 PAS domain MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SUPERFAMILY SSF55785 145 273 5.41E-15 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 SUPERFAMILY SSF47384 283 351 3.34E-12 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Pfam PF08448 PAS fold 162 276 9.5E-11 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Gene3D G3DSA:3.30.565.10 355 507 3.9E-41 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 350 7.0E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Gene3D G3DSA:3.30.450.20 143 277 4.4E-17 T 01-11-2018 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 Gene3D G3DSA:3.30.450.20 30 139 4.7E-15 T 01-11-2018 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 448 3.2E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 500 3.2E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 462 3.2E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18925 9ab04155033bca75a6a666511d26411f 520 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 3.2E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 123 1.0E-17 T 01-11-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 47.707 T 01-11-2018 IPR022897 HTH-type transcription regulator MntR MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 Gene3D G3DSA:1.10.60.10 74 142 1.3E-31 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 6.8E-25 T 01-11-2018 IPR022687 DTXR-type HTH domain GO:0003677 MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 SUPERFAMILY SSF47979 63 130 3.37E-18 T 01-11-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 SUPERFAMILY SSF46785 3 62 3.77E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 Gene3D G3DSA:1.10.10.10 1 73 2.5E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21990 8f2c2fd38c3e1dfcc68c0a69b6543dd1 142 SMART SM00529 24 123 1.7E-43 T 01-11-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 MLA2C4_08405 b4f8357ef1725de71766414eb38f4864 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_08405 b4f8357ef1725de71766414eb38f4864 449 Pfam PF00202 Aminotransferase class-III 30 445 1.3E-110 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_08405 b4f8357ef1725de71766414eb38f4864 449 SUPERFAMILY SSF53383 19 447 1.65E-123 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_08405 b4f8357ef1725de71766414eb38f4864 449 Gene3D G3DSA:3.40.640.10 64 338 2.7E-153 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_08405 b4f8357ef1725de71766414eb38f4864 449 PIRSF PIRSF000521 28 449 2.0E-37 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_08405 b4f8357ef1725de71766414eb38f4864 449 Gene3D G3DSA:3.90.1150.10 13 446 2.7E-153 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Gene3D G3DSA:1.10.540.10 35 143 1.9E-129 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Gene3D G3DSA:1.20.140.10 249 406 1.9E-129 T 01-11-2018 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 409 3.8E-38 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Gene3D G3DSA:1.20.140.10 428 569 8.1E-28 T 01-11-2018 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 368 387 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Gene3D G3DSA:2.40.110.10 144 248 1.9E-129 T 01-11-2018 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 SUPERFAMILY SSF56645 20 260 1.02E-73 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 141 6.3E-26 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 237 1.8E-24 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MLA2C4_12125 af40e19c9a3aeef99bdf97991cde03c2 569 SUPERFAMILY SSF47203 254 427 8.7E-47 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MLA2C4_18115 77d5981d1683df05ee9716ac61270eab 236 Gene3D G3DSA:3.40.50.1240 2 236 8.4E-65 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_18115 77d5981d1683df05ee9716ac61270eab 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 223 2.6E-32 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_18115 77d5981d1683df05ee9716ac61270eab 236 SMART SM00855 14 188 5.6E-16 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_18115 77d5981d1683df05ee9716ac61270eab 236 PIRSF PIRSF000709 8 113 4.7E-6 T 01-11-2018 MLA2C4_18115 77d5981d1683df05ee9716ac61270eab 236 SUPERFAMILY SSF53254 14 232 1.8E-44 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_14460 f18b7b61b0d5c941aab1a87bf8058913 359 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 356 1.7E-82 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_14460 f18b7b61b0d5c941aab1a87bf8058913 359 Pfam PF03845 Spore germination protein 8 320 2.0E-28 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 SMART SM00382 361 555 1.1E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 Gene3D G3DSA:1.20.1560.10 4 318 5.0E-40 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 Pfam PF00005 ABC transporter 352 501 1.2E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 Gene3D G3DSA:3.40.50.300 319 568 1.3E-73 T 01-11-2018 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 SUPERFAMILY SSF90123 4 316 3.14E-47 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 16 542 2.3E-171 T 01-11-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 Pfam PF00664 ABC transporter transmembrane region 19 265 9.2E-26 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_09875 8a278d9c8337fe2422e90bfc7141b04a 571 SUPERFAMILY SSF52540 325 565 8.98E-68 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21420 bf9bdd02766d4537a374b64e0fffa200 183 Pfam PF13302 Acetyltransferase (GNAT) domain 16 156 1.2E-16 T 01-11-2018 IPR000182 GNAT domain MLA2C4_21420 bf9bdd02766d4537a374b64e0fffa200 183 SUPERFAMILY SSF55729 9 182 8.02E-36 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21420 bf9bdd02766d4537a374b64e0fffa200 183 Gene3D G3DSA:3.40.630.30 6 182 3.7E-36 T 01-11-2018 MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 SUPERFAMILY SSF54631 204 341 6.57E-32 T 01-11-2018 MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 SMART SM01091 354 431 9.0E-17 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 Pfam PF03471 Transporter associated domain 355 429 2.7E-13 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 SUPERFAMILY SSF56176 349 429 7.91E-14 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 Gene3D G3DSA:3.30.465.10 351 434 7.7E-14 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 Gene3D G3DSA:3.10.580.10 197 350 9.9E-51 T 01-11-2018 MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 Pfam PF00571 CBS domain 289 338 0.0011 T 01-11-2018 IPR000644 CBS domain MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 Pfam PF00571 CBS domain 218 270 2.3E-8 T 01-11-2018 IPR000644 CBS domain MLA2C4_11440 6cf17bc67550380ebb6d8b51e47044a2 451 Pfam PF01595 Domain of unknown function DUF21 8 201 1.5E-47 T 01-11-2018 IPR002550 CNNM, transmembrane domain MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 2.6E-186 T 01-11-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 7.2E-27 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 Gene3D G3DSA:3.90.1170.30 336 423 5.3E-34 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 305 2.8E-48 T 01-11-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 01-11-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 SUPERFAMILY SSF47648 1 69 1.44E-24 T 01-11-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.6E-24 T 01-11-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 PIRSF PIRSF000478 1 432 4.4E-171 T 01-11-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 SMART SM00941 345 418 2.3E-30 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 Gene3D G3DSA:1.20.970.10 1 67 3.3E-31 T 01-11-2018 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 SUPERFAMILY SSF54680 331 431 1.44E-29 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 Gene3D G3DSA:3.40.1030.10 69 335 1.8E-118 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09630 46f4876ce8fdae7f8d028c3b93462d5e 433 SUPERFAMILY SSF52418 69 329 6.8E-93 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_09595 7b9132a0a00c3a7cbebd4b2abe1a8970 386 Gene3D G3DSA:1.20.1170.10 45 386 5.4E-128 T 01-11-2018 MLA2C4_09595 7b9132a0a00c3a7cbebd4b2abe1a8970 386 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 42 215 1.2E-54 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_09595 7b9132a0a00c3a7cbebd4b2abe1a8970 386 SUPERFAMILY SSF58100 39 385 4.97E-70 T 01-11-2018 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.135 T 01-11-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 01-11-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 Gene3D G3DSA:3.90.930.12 84 179 4.4E-41 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.4E-34 T 01-11-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.4E-34 T 01-11-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.4E-34 T 01-11-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 2.4E-76 T 01-11-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 SUPERFAMILY SSF56053 1 83 7.44E-27 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 Gene3D G3DSA:3.90.930.12 1 83 8.6E-31 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 PIRSF PIRSF002162 1 178 2.1E-49 T 01-11-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 Pfam PF00347 Ribosomal protein L6 11 83 1.4E-22 T 01-11-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 Pfam PF00347 Ribosomal protein L6 91 165 2.2E-21 T 01-11-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00750 1540fe89ca9095efee3248b347f6d628 179 SUPERFAMILY SSF56053 84 177 2.65E-35 T 01-11-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_11385 81d5e1753a4cad768f1d4ef91be67234 409 SUPERFAMILY SSF103473 10 398 5.1E-38 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_11385 81d5e1753a4cad768f1d4ef91be67234 409 Pfam PF07690 Major Facilitator Superfamily 16 351 1.8E-23 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_11385 81d5e1753a4cad768f1d4ef91be67234 409 Gene3D G3DSA:1.20.1250.20 5 392 2.2E-30 T 01-11-2018 MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 Gene3D G3DSA:1.20.120.530 83 216 1.5E-20 T 01-11-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 SUPERFAMILY SSF46785 10 96 2.57E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 SUPERFAMILY SSF48008 88 216 8.37E-17 T 01-11-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 Gene3D G3DSA:1.10.10.10 11 78 8.7E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 Pfam PF07729 FCD domain 88 207 7.6E-21 T 01-11-2018 IPR011711 GntR, C-terminal MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 SMART SM00895 87 211 1.2E-8 T 01-11-2018 IPR011711 GntR, C-terminal MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 76 2.5E-15 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.8E-6 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.8E-6 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_08955 991c6280fa3462c174ee7ca5ff755db3 223 SMART SM00345 19 77 3.0E-13 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Pfam PF00403 Heavy-metal-associated domain 9 68 2.0E-15 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Pfam PF00403 Heavy-metal-associated domain 77 137 1.2E-15 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 264 800 2.2E-125 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 800 4.6E-187 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Gene3D G3DSA:3.30.70.100 1 72 2.4E-22 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 SUPERFAMILY SSF56784 496 797 3.46E-63 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 212 237 2.0E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 32 55 2.0E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 192 212 2.0E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 2.0E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Pfam PF00122 E1-E2 ATPase 297 476 3.3E-59 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Gene3D G3DSA:3.40.50.1000 479 749 1.5E-97 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 269 783 8.4E-94 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 SUPERFAMILY SSF55008 3 71 6.02E-20 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 SUPERFAMILY SSF55008 74 145 1.57E-20 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Gene3D G3DSA:3.40.1110.10 509 629 1.5E-97 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 500 506 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 138 5.9E-13 T 01-11-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 70 4.3E-9 T 01-11-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Gene3D G3DSA:3.30.70.100 73 148 1.4E-22 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Gene3D G3DSA:2.70.150.20 289 401 3.4E-44 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 79 108 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 654 1.7E-28 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 346 360 1.7E-28 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 512 1.7E-28 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 697 716 1.7E-28 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 633 1.7E-28 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 732 1.7E-28 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 214 233 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 286 304 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 419 433 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 674 691 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 118 138 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 481 496 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 PRINTS PR00943 Copper-transporting ATPase signature 266 285 2.2E-16 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 SUPERFAMILY SSF81665 259 484 5.62E-11 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 229 799 1.9E-204 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 711 4.3E-48 T 01-11-2018 MLA2C4_19480 b4f6b6e56d3ac517261a7fe8806acd45 806 SUPERFAMILY SSF81653 300 396 6.67E-31 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_14135 33b809386527d3c9aadf3559574f0bbb 199 SUPERFAMILY SSF48317 4 171 3.92E-35 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_14135 33b809386527d3c9aadf3559574f0bbb 199 SMART SM00014 58 165 3.2E-15 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_14135 33b809386527d3c9aadf3559574f0bbb 199 Pfam PF01569 PAP2 superfamily 59 166 7.1E-18 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_14135 33b809386527d3c9aadf3559574f0bbb 199 Gene3D G3DSA:1.20.144.10 1 181 4.4E-19 T 01-11-2018 MLA2C4_27785 0963328818ebd19bd54690935b3e1065 120 Gene3D G3DSA:2.40.50.480 33 118 2.2E-16 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_27785 0963328818ebd19bd54690935b3e1065 120 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 2 116 3.8E-9 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_27785 0963328818ebd19bd54690935b3e1065 120 SUPERFAMILY SSF159121 39 118 1.12E-17 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_27785 0963328818ebd19bd54690935b3e1065 120 Pfam PF06486 Protein of unknown function (DUF1093) 43 107 5.0E-10 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 SUPERFAMILY SSF50129 1 162 1.67E-29 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 Gene3D G3DSA:3.90.180.10 24 319 2.5E-86 T 01-11-2018 MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 Gene3D G3DSA:3.40.50.720 139 276 2.5E-86 T 01-11-2018 MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 SUPERFAMILY SSF51735 133 303 1.86E-37 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 Pfam PF00107 Zinc-binding dehydrogenase 169 291 1.6E-28 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 SMART SM00829 11 326 1.7E-13 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_14130 d0519ca5ebf62ce8a344fdd4fef58421 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 124 8.8E-12 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 1.0E-45 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 373 39.692 T 01-11-2018 IPR000158 Cell division protein FtsZ GO:0005525 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 Gene3D G3DSA:3.30.1330.20 221 327 7.7E-41 T 01-11-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 SUPERFAMILY SSF55307 204 318 3.89E-43 T 01-11-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 SMART SM00864 13 205 1.9E-119 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 Gene3D G3DSA:3.40.50.1440 3 220 3.3E-86 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 01-11-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 Pfam PF12327 FtsZ family, C-terminal domain 222 316 5.2E-32 T 01-11-2018 IPR024757 Cell division protein FtsZ, C-terminal MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 01-11-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 SUPERFAMILY SSF52490 12 208 6.8E-74 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 5 340 8.2E-139 T 01-11-2018 IPR000158 Cell division protein FtsZ GO:0005525 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 SMART SM00865 207 324 2.9E-52 T 01-11-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-52 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-52 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-52 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MLA2C4_20415 70b9fbb7c2b64b16ad3ba67d0daa9947 384 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-52 T 01-11-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MLA2C4_07115 db837e9dbfd4c57cec6829cfb94fc33d 163 Gene3D G3DSA:3.30.479.10 29 103 5.8E-23 T 01-11-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MLA2C4_07115 db837e9dbfd4c57cec6829cfb94fc33d 163 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 34 123 2.0E-30 T 01-11-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MLA2C4_07115 db837e9dbfd4c57cec6829cfb94fc33d 163 Gene3D G3DSA:3.30.479.10 104 162 3.2E-9 T 01-11-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MLA2C4_07115 db837e9dbfd4c57cec6829cfb94fc33d 163 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 34 158 2.8E-35 T 01-11-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MLA2C4_07115 db837e9dbfd4c57cec6829cfb94fc33d 163 SUPERFAMILY SSF55620 29 158 1.11E-36 T 01-11-2018 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 1 457 52.987 T 01-11-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 Gene3D G3DSA:3.40.50.800 362 458 1.8E-31 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 Pfam PF03129 Anticodon binding domain 367 454 1.0E-22 T 01-11-2018 IPR004154 Anticodon-binding MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 402 421 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 146 158 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 199 216 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 323 335 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 167 184 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 23 37 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 216 226 5.9E-53 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 SUPERFAMILY SSF55681 2 370 2.68E-124 T 01-11-2018 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 3 241 4.6E-92 T 01-11-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 163 338 2.6E-9 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_25575 ee49f61fa4719e451e917382260a649a 458 SUPERFAMILY SSF52954 354 456 1.36E-33 T 01-11-2018 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 87.737 T 01-11-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 Gene3D G3DSA:3.20.20.70 1 487 3.6E-227 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 7.3E-168 T 01-11-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 PIRSF PIRSF000130 1 487 9.0E-211 T 01-11-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 SMART SM00116 161 209 7.6E-9 T 01-11-2018 IPR000644 CBS domain MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 SMART SM00116 98 148 2.1E-6 T 01-11-2018 IPR000644 CBS domain MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 SMART SM01240 9 474 0.0 T 01-11-2018 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 1.6E-201 T 01-11-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 Pfam PF00571 CBS domain 97 144 3.4E-6 T 01-11-2018 IPR000644 CBS domain MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 Pfam PF00571 CBS domain 153 204 4.5E-8 T 01-11-2018 IPR000644 CBS domain MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 SUPERFAMILY SSF54631 66 208 7.2E-32 T 01-11-2018 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 SUPERFAMILY SSF51412 5 478 1.05E-125 T 01-11-2018 MLA2C4_00065 69d7ab406d1610d540182c170af04cff 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 01-11-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MLA2C4_20495 5d84c767e76b185b45ffc84e60111c0d 168 SUPERFAMILY SSF46689 6 62 2.34E-6 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_20495 5d84c767e76b185b45ffc84e60111c0d 168 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 155 1.4E-56 T 01-11-2018 IPR014243 Transcription factor, RsfA MLA2C4_20495 5d84c767e76b185b45ffc84e60111c0d 168 Pfam PF13921 Myb-like DNA-binding domain 9 62 5.3E-7 T 01-11-2018 MLA2C4_20495 5d84c767e76b185b45ffc84e60111c0d 168 SMART SM00717 5 59 9.0E-4 T 01-11-2018 IPR001005 SANT/Myb domain MLA2C4_20495 5d84c767e76b185b45ffc84e60111c0d 168 Gene3D G3DSA:1.10.10.60 8 86 2.4E-6 T 01-11-2018 MLA2C4_03605 67b5bbc99db14bbe7dbf4ccfc3c53660 424 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 30 242 0.008 T 01-11-2018 MLA2C4_03605 67b5bbc99db14bbe7dbf4ccfc3c53660 424 Pfam PF06725 3D domain 365 424 4.5E-17 T 01-11-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MLA2C4_03605 67b5bbc99db14bbe7dbf4ccfc3c53660 424 SUPERFAMILY SSF50685 350 404 1.5E-7 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Gene3D G3DSA:3.30.450.40 238 361 6.3E-7 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 SUPERFAMILY SSF55874 430 574 4.45E-16 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Pfam PF07694 5TMR of 5TMR-LYT 26 204 3.9E-49 T 01-11-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Gene3D G3DSA:1.10.1760.20 81 213 5.8E-5 T 01-11-2018 MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 238 361 6.0E-8 T 01-11-2018 IPR039472 Sporulation stage V protein T, GAF domain MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Gene3D G3DSA:3.30.565.10 426 578 4.9E-17 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 SMART SM00065 235 370 1.9E-10 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 SUPERFAMILY SSF55781 239 361 3.36E-8 T 01-11-2018 MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 SMART SM00387 468 577 1.3E-4 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 575 1.2E-9 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_28185 73d9c3f7a6ccbfcb5bdb39a0a4a7128e 589 Pfam PF06580 Histidine kinase 375 453 2.4E-24 T 01-11-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MLA2C4_12120 54249ee2c8f27997b1f475410a4a1d26 302 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 256 1.5E-52 T 01-11-2018 MLA2C4_12120 54249ee2c8f27997b1f475410a4a1d26 302 SUPERFAMILY SSF51621 9 294 3.86E-98 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MLA2C4_12120 54249ee2c8f27997b1f475410a4a1d26 302 Gene3D G3DSA:3.20.20.60 1 302 2.4E-114 T 01-11-2018 MLA2C4_12120 54249ee2c8f27997b1f475410a4a1d26 302 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 01-11-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MLA2C4_12120 54249ee2c8f27997b1f475410a4a1d26 302 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 16 295 3.8E-130 T 01-11-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MLA2C4_12120 54249ee2c8f27997b1f475410a4a1d26 302 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 296 48.422 T 01-11-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 Hamap MF_00564 Ribonuclease PH [rph]. 11 238 43.875 T 01-11-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 SUPERFAMILY SSF54211 1 140 1.52E-43 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 SUPERFAMILY SSF55666 151 238 4.32E-25 T 01-11-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 01-11-2018 IPR018336 Ribonuclease PH, conserved site MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 Gene3D G3DSA:3.30.230.70 13 245 1.6E-65 T 01-11-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 Pfam PF03725 3' exoribonuclease family, domain 2 159 224 2.9E-11 T 01-11-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 4.2E-23 T 01-11-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_23370 d10cede866e05885d04c67a1f4a935b9 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 1.1E-116 T 01-11-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MLA2C4_08665 4d26c3db88b18c5c449a895d168b0d8b 315 Pfam PF12181 DNA binding domain of the motility gene repressor (MogR) 12 159 3.8E-81 T 01-11-2018 IPR021009 Motility repressor MogR, DNA-dinding domain MLA2C4_08665 4d26c3db88b18c5c449a895d168b0d8b 315 Gene3D G3DSA:1.20.120.1030 5 127 1.8E-53 T 01-11-2018 IPR038245 MogR, N-terminal domain superfamily MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Gene3D G3DSA:2.60.40.1180 762 849 5.0E-21 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 SUPERFAMILY SSF49452 39 133 1.67E-27 T 01-11-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 227 827 2.7E-279 T 01-11-2018 IPR011840 Pullulanase, type I MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Pfam PF03714 Bacterial pullanase-associated domain 41 131 2.9E-22 T 01-11-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 238 316 3.2E-13 T 01-11-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Gene3D G3DSA:2.60.40.2320 140 228 2.1E-5 T 01-11-2018 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 SUPERFAMILY SSF51445 335 760 1.23E-127 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 SMART SM00642 353 752 7.5E-8 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 SUPERFAMILY SSF81296 231 336 4.8E-21 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 PIRSF PIRSF000463 127 550 2.7E-31 T 01-11-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 PIRSF PIRSF000463 645 840 0.15 T 01-11-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Gene3D G3DSA:2.60.40.10 229 337 4.7E-31 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Gene3D G3DSA:2.60.40.1110 37 134 5.0E-27 T 01-11-2018 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Pfam PF00128 Alpha amylase, catalytic domain 516 713 8.3E-5 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Pfam PF00128 Alpha amylase, catalytic domain 389 485 2.2E-10 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_14490 98b52e6f2e93b5b41196f817f5610db7 854 Gene3D G3DSA:3.20.20.80 338 761 4.3E-180 T 01-11-2018 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 4 269 2.5E-89 T 01-11-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 SUPERFAMILY SSF53067 5 270 2.17E-57 T 01-11-2018 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 PIRSF PIRSF036940 1 272 7.7E-124 T 01-11-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 Pfam PF03630 Fumble 5 269 6.7E-35 T 01-11-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 Gene3D G3DSA:3.30.420.40 76 256 5.2E-89 T 01-11-2018 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 Gene3D G3DSA:3.30.420.40 5 268 5.2E-89 T 01-11-2018 MLA2C4_15350 1efea6a01f2d20eb9066df8dbcdf44eb 276 Hamap MF_01273 Type II pantothenate kinase [coaW]. 3 270 48.441 T 01-11-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MLA2C4_10330 caa146ab2eccf894357a71abd95e3b8d 553 Gene3D G3DSA:3.90.76.10 75 196 1.3E-177 T 01-11-2018 MLA2C4_10330 caa146ab2eccf894357a71abd95e3b8d 553 Gene3D G3DSA:3.40.190.10 56 540 1.3E-177 T 01-11-2018 MLA2C4_10330 caa146ab2eccf894357a71abd95e3b8d 553 PIRSF PIRSF002741 1 553 6.6E-100 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_10330 caa146ab2eccf894357a71abd95e3b8d 553 Gene3D G3DSA:3.10.105.10 298 523 1.3E-177 T 01-11-2018 MLA2C4_10330 caa146ab2eccf894357a71abd95e3b8d 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 470 3.4E-77 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_10330 caa146ab2eccf894357a71abd95e3b8d 553 SUPERFAMILY SSF53850 37 549 2.35E-118 T 01-11-2018 MLA2C4_26410 1fb154d46fa0c0d4e22f36a7ef973697 134 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 121 19.349 T 01-11-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MLA2C4_26410 1fb154d46fa0c0d4e22f36a7ef973697 134 TIGRFAM TIGR00494 crcB: protein CrcB 5 119 6.5E-27 T 01-11-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MLA2C4_26410 1fb154d46fa0c0d4e22f36a7ef973697 134 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 116 1.6E-24 T 01-11-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MLA2C4_18640 5ac595f2311b56718bf1c7511e25ad1a 297 SMART SM00382 26 204 4.1E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_18640 5ac595f2311b56718bf1c7511e25ad1a 297 Pfam PF00005 ABC transporter 19 156 1.1E-24 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18640 5ac595f2311b56718bf1c7511e25ad1a 297 Gene3D G3DSA:3.40.50.300 1 232 3.0E-54 T 01-11-2018 MLA2C4_18640 5ac595f2311b56718bf1c7511e25ad1a 297 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_18640 5ac595f2311b56718bf1c7511e25ad1a 297 SUPERFAMILY SSF52540 2 215 1.65E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 Gene3D G3DSA:3.60.21.10 7 317 8.8E-93 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 SUPERFAMILY SSF56300 4 317 4.79E-84 T 01-11-2018 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 PRINTS PR01607 Apyrase family signature 373 396 1.3E-23 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 PRINTS PR01607 Apyrase family signature 463 482 1.3E-23 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 PRINTS PR01607 Apyrase family signature 7 25 1.3E-23 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 PRINTS PR01607 Apyrase family signature 191 208 1.3E-23 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 PRINTS PR01607 Apyrase family signature 253 273 1.3E-23 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 PRINTS PR01607 Apyrase family signature 226 249 1.3E-23 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 Pfam PF02872 5'-nucleotidase, C-terminal domain 330 489 1.1E-30 T 01-11-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 Pfam PF00149 Calcineurin-like phosphoesterase 9 243 4.4E-14 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 SUPERFAMILY SSF55816 315 526 1.44E-51 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 Gene3D G3DSA:3.90.780.10 319 527 2.0E-70 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_19190 80caa958744e18322e7e2a69b342788f 527 ProSitePatterns PS00786 5'-nucleotidase signature 2. 91 102 - T 01-11-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_06100 59024cbee6ced2ec417ccf827ed80485 300 SUPERFAMILY SSF47413 5 65 1.77E-15 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_06100 59024cbee6ced2ec417ccf827ed80485 300 SUPERFAMILY SSF48452 115 258 7.59E-9 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_06100 59024cbee6ced2ec417ccf827ed80485 300 Pfam PF12844 Helix-turn-helix domain 9 67 1.9E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_06100 59024cbee6ced2ec417ccf827ed80485 300 Gene3D G3DSA:1.25.40.10 1 298 1.0E-81 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_06100 59024cbee6ced2ec417ccf827ed80485 300 SMART SM00530 9 63 1.8E-9 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_00715 4d3f43dba4db11a4460bfa8f5c071032 66 SUPERFAMILY SSF46561 1 64 9.42E-24 T 01-11-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00715 4d3f43dba4db11a4460bfa8f5c071032 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.193 T 01-11-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00715 4d3f43dba4db11a4460bfa8f5c071032 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 01-11-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00715 4d3f43dba4db11a4460bfa8f5c071032 66 Gene3D G3DSA:1.10.287.310 1 66 4.3E-30 T 01-11-2018 MLA2C4_00715 4d3f43dba4db11a4460bfa8f5c071032 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.5E-24 T 01-11-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00715 4d3f43dba4db11a4460bfa8f5c071032 66 Pfam PF00831 Ribosomal L29 protein 4 60 2.6E-26 T 01-11-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 3.7E-17 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 SUPERFAMILY SSF46689 18 95 1.44E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 SUPERFAMILY SSF48498 93 204 9.74E-26 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 Pfam PF08359 YsiA-like protein, C-terminal region 73 204 3.8E-61 T 01-11-2018 IPR013570 Transcription regulator YsiA, C-terminal MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 Gene3D G3DSA:1.10.357.10 65 206 1.5E-33 T 01-11-2018 MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.2E-11 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.2E-11 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23525 a37f802568ccbf17077505f6b3faa409 210 Gene3D G3DSA:1.10.10.60 14 64 2.9E-23 T 01-11-2018 MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 Pfam PF01636 Phosphotransferase enzyme family 29 261 3.3E-12 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 PIRSF PIRSF031134 1 388 9.7E-155 T 01-11-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 Gene3D G3DSA:3.90.1200.10 112 388 4.3E-103 T 01-11-2018 MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 393 183.236 T 01-11-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 SUPERFAMILY SSF56112 2 369 3.35E-85 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 31 384 4.7E-134 T 01-11-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 MLA2C4_21095 4796c6b4df837266903b424eec5945c5 393 Gene3D G3DSA:3.30.200.20 1 111 2.6E-41 T 01-11-2018 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 2.0E-70 T 01-11-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 801 23.287 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Gene3D G3DSA:3.90.740.10 226 410 1.0E-281 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 SUPERFAMILY SSF52374 2 625 1.21E-145 T 01-11-2018 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Gene3D G3DSA:3.40.50.620 32 571 1.0E-281 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Gene3D G3DSA:2.30.210.10 572 587 1.0E-281 T 01-11-2018 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 SUPERFAMILY SSF50677 224 407 6.07E-55 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 SUPERFAMILY SSF47323 618 801 1.03E-43 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Gene3D G3DSA:3.10.20.590 744 801 8.0E-19 T 01-11-2018 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Gene3D G3DSA:1.10.730.10 599 740 3.8E-48 T 01-11-2018 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 1.2E-57 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Pfam PF08264 Anticodon-binding domain of tRNA 651 766 3.5E-22 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 1.7E-20 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 801 0.0 T 01-11-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MLA2C4_24645 078b8e2afb171479062070922d287eae 802 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.1E-16 T 01-11-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_15555 0fe5e4b33f7e4e4091d0791ec7994da3 366 SUPERFAMILY SSF55021 289 347 2.25E-7 T 01-11-2018 MLA2C4_15555 0fe5e4b33f7e4e4091d0791ec7994da3 366 Gene3D G3DSA:1.10.3660.10 181 295 6.0E-34 T 01-11-2018 MLA2C4_15555 0fe5e4b33f7e4e4091d0791ec7994da3 366 SUPERFAMILY SSF48179 175 283 2.61E-32 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_15555 0fe5e4b33f7e4e4091d0791ec7994da3 366 Gene3D G3DSA:3.40.50.720 1 179 7.1E-51 T 01-11-2018 MLA2C4_15555 0fe5e4b33f7e4e4091d0791ec7994da3 366 Pfam PF02153 Prephenate dehydrogenase 17 273 3.1E-77 T 01-11-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MLA2C4_15555 0fe5e4b33f7e4e4091d0791ec7994da3 366 SUPERFAMILY SSF51735 4 170 5.8E-46 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 SUPERFAMILY SSF54919 1 148 1.83E-60 T 01-11-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 01-11-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 36.259 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 7.5E-58 T 01-11-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 Gene3D G3DSA:3.30.70.141 1 148 1.6E-64 T 01-11-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 SMART SM00562 1 138 1.2E-88 T 01-11-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 3.4E-50 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 3.4E-50 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 3.4E-50 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 3.4E-50 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07970 942ff72c8c5c20899ce39732b8704645 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 3.4E-50 T 01-11-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 SMART SM00345 17 76 2.1E-16 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 Gene3D G3DSA:3.40.640.10 152 372 7.2E-104 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 SUPERFAMILY SSF46785 6 79 1.87E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 Pfam PF00155 Aminotransferase class I and II 128 471 4.0E-33 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 Gene3D G3DSA:1.10.10.10 3 77 2.9E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.7E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.7E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 SUPERFAMILY SSF53383 111 475 6.05E-94 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.8E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_16040 3b8a9779d32a421e0288b05e4c9e2b18 480 Gene3D G3DSA:3.90.1150.10 115 474 7.2E-104 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_06010 6d3f858ece750185ca327be2a8bce2a9 128 Pfam PF10970 Spore germination protein GerPE 5 128 9.9E-48 T 01-11-2018 IPR024496 Spore germination protein GerPE MLA2C4_06010 6d3f858ece750185ca327be2a8bce2a9 128 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 128 3.0E-66 T 01-11-2018 IPR024496 Spore germination protein GerPE MLA2C4_18330 08e52e14b3c86a9bd035472c888aa323 299 Gene3D G3DSA:3.10.180.10 8 172 6.0E-27 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18330 08e52e14b3c86a9bd035472c888aa323 299 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 187 251 1.7E-4 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18330 08e52e14b3c86a9bd035472c888aa323 299 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 146 6.6E-8 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18330 08e52e14b3c86a9bd035472c888aa323 299 SUPERFAMILY SSF54593 185 297 3.16E-22 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18330 08e52e14b3c86a9bd035472c888aa323 299 SUPERFAMILY SSF54593 3 159 5.84E-27 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18330 08e52e14b3c86a9bd035472c888aa323 299 Gene3D G3DSA:3.10.180.10 185 299 1.3E-23 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_09645 feeeb29af65da57bab12b3e4f676e1f8 159 PIRSF PIRSF021441 1 159 6.9E-67 T 01-11-2018 IPR031306 CcdC protein MLA2C4_09645 feeeb29af65da57bab12b3e4f676e1f8 159 Pfam PF07301 Protein of unknown function (DUF1453) 5 148 3.1E-57 T 01-11-2018 IPR009916 Protein of unknown function DUF1453 MLA2C4_02380 63fecbe8f6717a64fdbf581128feb1f9 437 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 9 380 8.3E-60 T 01-11-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MLA2C4_02380 63fecbe8f6717a64fdbf581128feb1f9 437 Gene3D G3DSA:3.40.720.10 2 436 1.6E-78 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_02380 63fecbe8f6717a64fdbf581128feb1f9 437 SUPERFAMILY SSF53649 7 420 1.21E-77 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.5E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.5E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 SUPERFAMILY SSF46785 7 82 3.0E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.3E-12 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 Pfam PF00155 Aminotransferase class I and II 135 420 1.5E-17 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 SMART SM00345 18 77 1.3E-10 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 Gene3D G3DSA:1.10.10.10 5 84 1.9E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 SUPERFAMILY SSF53383 101 458 4.9E-72 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_17575 9f9c35ba3e9dcaf194a89da63f0839c4 459 Gene3D G3DSA:3.40.640.10 90 452 6.2E-104 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_20335 a65d38b2f65ccd676e87f65056f46c4e 427 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 335 355 - T 01-11-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MLA2C4_20335 a65d38b2f65ccd676e87f65056f46c4e 427 Pfam PF00860 Permease family 16 389 2.1E-111 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_20335 a65d38b2f65ccd676e87f65056f46c4e 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 412 4.0E-135 T 01-11-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 Gene3D G3DSA:1.10.10.10 1 68 2.4E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 SMART SM00345 7 66 5.1E-15 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 Pfam PF00155 Aminotransferase class I and II 81 437 9.3E-25 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 SUPERFAMILY SSF53383 63 444 3.48E-67 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 Gene3D G3DSA:3.40.640.10 69 437 1.5E-82 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 4.9E-12 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_13740 6b022d8b8e549d5cc1ad1b57facc97a3 463 SUPERFAMILY SSF46785 3 70 2.13E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08120 2d72f076987d5d63198219836b9c0a52 167 Gene3D G3DSA:3.10.450.40 94 164 3.7E-20 T 01-11-2018 MLA2C4_08120 2d72f076987d5d63198219836b9c0a52 167 SUPERFAMILY SSF54403 34 94 5.1E-18 T 01-11-2018 MLA2C4_08120 2d72f076987d5d63198219836b9c0a52 167 SUPERFAMILY SSF54403 94 164 2.04E-15 T 01-11-2018 MLA2C4_08120 2d72f076987d5d63198219836b9c0a52 167 Gene3D G3DSA:3.10.450.40 23 93 1.9E-21 T 01-11-2018 MLA2C4_05500 23622bcd4efea492a87b76e22e273eb3 186 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 2.9E-63 T 01-11-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 MLA2C4_05500 23622bcd4efea492a87b76e22e273eb3 186 SUPERFAMILY SSF110391 8 181 2.62E-62 T 01-11-2018 IPR035928 GlpP-like superfamily MLA2C4_05500 23622bcd4efea492a87b76e22e273eb3 186 Gene3D G3DSA:3.20.20.400 1 186 5.5E-71 T 01-11-2018 IPR035928 GlpP-like superfamily MLA2C4_05500 23622bcd4efea492a87b76e22e273eb3 186 PIRSF PIRSF016897 1 186 1.7E-64 T 01-11-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:2.40.50.140 315 387 1.1E-29 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SUPERFAMILY SSF50249 314 396 6.85E-28 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:2.20.70.80 388 425 3.5E-11 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 319 395 6.8E-34 T 01-11-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 663 1.6E-270 T 01-11-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 116 145 - T 01-11-2018 IPR018239 NAD-dependent DNA ligase, active site MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SUPERFAMILY SSF47781 400 580 1.48E-65 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SUPERFAMILY SSF52113 594 667 1.13E-19 T 01-11-2018 IPR036420 BRCT domain superfamily MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:3.40.50.10190 581 668 4.6E-25 T 01-11-2018 IPR036420 BRCT domain superfamily MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 404 430 5.0E-10 T 01-11-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 6 315 7.1E-130 T 01-11-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:1.10.150.20 428 500 2.2E-31 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:3.30.470.90 74 314 9.6E-103 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:1.10.150.20 501 580 3.4E-28 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 665 2.5E-14 T 01-11-2018 IPR001357 BRCT domain MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SUPERFAMILY SSF56091 4 313 3.52E-122 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SMART SM00278 476 495 1.2 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SMART SM00278 442 461 120.0 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SMART SM00278 540 559 3.8 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SMART SM00292 593 669 1.6E-14 T 01-11-2018 IPR001357 BRCT domain MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Hamap MF_01588 DNA ligase [ligA]. 4 667 53.2 T 01-11-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Gene3D G3DSA:1.10.287.610 1 73 7.9E-26 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 328 343 - T 01-11-2018 IPR033136 NAD-dependent DNA ligase, conserved site MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 PIRSF PIRSF001604 1 669 2.3E-262 T 01-11-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 SMART SM00532 5 444 6.2E-277 T 01-11-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Pfam PF14520 Helix-hairpin-helix domain 444 496 4.1E-6 T 01-11-2018 MLA2C4_01835 518cda9fdde3403bc00230930d5f4f26 669 Pfam PF12826 Helix-hairpin-helix motif 506 568 9.3E-25 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 Pfam PF03486 HI0933-like protein 3 413 1.7E-157 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 412 1.3E-145 T 01-11-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.4E-10 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 1.4E-10 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.4E-10 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 SUPERFAMILY SSF160996 193 361 2.88E-47 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 Gene3D G3DSA:1.10.8.260 279 343 6.0E-124 T 01-11-2018 IPR023166 HI0933-like insert domain superfamily MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 Gene3D G3DSA:3.50.50.60 6 409 6.0E-124 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 SUPERFAMILY SSF51905 1 415 2.06E-65 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.8E-7 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.8E-7 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 390 1.8E-7 T 01-11-2018 MLA2C4_24485 28d22062ccae470401d7c488c9577cd0 423 Gene3D G3DSA:2.40.30.10 192 360 6.0E-124 T 01-11-2018 MLA2C4_06480 d9d7480e914c07963bee8501ae83e4b0 496 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 491 1.0E-219 T 01-11-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MLA2C4_06480 d9d7480e914c07963bee8501ae83e4b0 496 Gene3D G3DSA:1.20.1730.10 23 495 7.1E-103 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily MLA2C4_06480 d9d7480e914c07963bee8501ae83e4b0 496 Pfam PF00474 Sodium:solute symporter family 35 437 1.8E-105 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_06480 d9d7480e914c07963bee8501ae83e4b0 496 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site MLA2C4_06480 d9d7480e914c07963bee8501ae83e4b0 496 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 437 6.6E-98 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 Gene3D G3DSA:3.40.50.790 68 159 1.1E-85 T 01-11-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 Gene3D G3DSA:3.30.190.20 21 225 1.1E-85 T 01-11-2018 MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 01-11-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 PIRSF PIRSF002155 1 227 4.3E-84 T 01-11-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 6.9E-108 T 01-11-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.121 T 01-11-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 6.5E-57 T 01-11-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MLA2C4_00610 14a6003de189f072436cb43685ee1e35 230 SUPERFAMILY SSF56808 6 226 7.46E-86 T 01-11-2018 IPR023674 Ribosomal protein L1-like MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 376 579 3.1E-41 T 01-11-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 327 4.4E-136 T 01-11-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 Gene3D G3DSA:1.25.40.340 366 583 3.4E-55 T 01-11-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 Gene3D G3DSA:3.30.1180.20 183 328 5.2E-52 T 01-11-2018 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 Pfam PF02734 DAK2 domain 398 579 1.1E-52 T 01-11-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 SMART SM01120 397 580 3.6E-59 T 01-11-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 Gene3D G3DSA:3.40.50.10440 13 182 4.4E-64 T 01-11-2018 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 SUPERFAMILY SSF101473 357 580 2.22E-45 T 01-11-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 SUPERFAMILY SSF82549 1 329 2.88E-121 T 01-11-2018 MLA2C4_05185 d1bb2d7451751f4ac1cb4dfb955a213e 583 Pfam PF02733 Dak1 domain 18 326 6.9E-126 T 01-11-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SUPERFAMILY SSF51246 342 460 8.89E-38 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SUPERFAMILY SSF52440 4 118 4.82E-44 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Pfam PF00364 Biotin-requiring enzyme 1080 1146 3.0E-19 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Pfam PF00682 HMGL-like 535 807 1.3E-27 T 01-11-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:2.40.50.100 1071 1147 6.9E-26 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 121 327 8.7E-80 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:3.10.600.10 510 1062 2.3E-298 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SUPERFAMILY SSF89000 835 1012 3.33E-59 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:1.10.10.2790 945 980 2.3E-298 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 347 454 2.6E-33 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SUPERFAMILY SSF51230 1072 1146 8.64E-23 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:3.30.470.130 1 462 3.5E-194 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:1.10.472.90 820 944 2.3E-298 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SMART SM00878 347 454 7.3E-52 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:3.20.20.70 515 819 2.3E-298 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 9 1146 0.0 T 01-11-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Pfam PF02436 Conserved carboxylase domain 830 1030 8.2E-77 T 01-11-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Gene3D G3DSA:3.10.600.10 464 509 9.8E-6 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 115 2.3E-42 T 01-11-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 PIRSF PIRSF001594 2 1148 0.0 T 01-11-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SUPERFAMILY SSF56059 89 335 1.77E-68 T 01-11-2018 MLA2C4_20615 dfb32ffdbecfbcd081d385f0a545d0a2 1148 SUPERFAMILY SSF51569 527 838 2.75E-86 T 01-11-2018 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 Gene3D G3DSA:3.30.70.260 1 80 1.3E-29 T 01-11-2018 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 Pfam PF10369 Small subunit of acetolactate synthase 85 156 3.4E-26 T 01-11-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 Gene3D G3DSA:3.30.70.1150 84 164 1.5E-27 T 01-11-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 9.0E-29 T 01-11-2018 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 157 4.4E-59 T 01-11-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 SUPERFAMILY SSF55021 2 77 7.13E-19 T 01-11-2018 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 SUPERFAMILY SSF55021 77 157 6.56E-24 T 01-11-2018 MLA2C4_07395 5caf22c6faa643450eb7a1cb42b1f07d 169 Pfam PF01842 ACT domain 7 68 4.9E-14 T 01-11-2018 IPR002912 ACT domain MLA2C4_05420 1fe3c5ba82c077557af8ec3b69dba58c 974 SUPERFAMILY SSF52540 1 962 5.66E-15 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05420 1fe3c5ba82c077557af8ec3b69dba58c 974 Pfam PF13514 AAA domain 1 198 2.6E-27 T 01-11-2018 IPR038734 Uncharacterized protein YhaN, AAA domain MLA2C4_05420 1fe3c5ba82c077557af8ec3b69dba58c 974 Gene3D G3DSA:3.40.50.300 740 973 1.8E-18 T 01-11-2018 MLA2C4_05420 1fe3c5ba82c077557af8ec3b69dba58c 974 Gene3D G3DSA:3.40.50.300 1 263 4.8E-21 T 01-11-2018 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 SUPERFAMILY SSF52507 1 179 6.8E-60 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 Gene3D G3DSA:3.40.50.10300 186 401 5.8E-92 T 01-11-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 Gene3D G3DSA:3.40.50.1950 1 185 2.6E-59 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 Pfam PF02441 Flavoprotein 5 177 8.4E-45 T 01-11-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 366 1.5E-71 T 01-11-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 SUPERFAMILY SSF102645 183 396 4.58E-78 T 01-11-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MLA2C4_20220 0bd5ac98f6f2d7d8782d12280fe3b8a2 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 392 6.2E-152 T 01-11-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 SUPERFAMILY SSF103263 1 388 2.88E-151 T 01-11-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 Pfam PF01264 Chorismate synthase 1 364 7.7E-126 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 PIRSF PIRSF001456 1 385 2.1E-133 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 6.7E-132 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 Gene3D G3DSA:3.60.150.10 1 389 9.5E-158 T 01-11-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.983 T 01-11-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_07975 0ef7c25121e2e6a778cb13a364bf50da 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 01-11-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 515 1.2E-157 T 01-11-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 52 66 9.2E-7 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 9.2E-7 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 11 25 9.2E-7 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Gene3D G3DSA:3.40.50.620 203 395 4.4E-76 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 11 197 5.8E-84 T 01-11-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Pfam PF00117 Glutamine amidotransferase class-I 13 192 2.3E-46 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 8 515 55.572 T 01-11-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Gene3D G3DSA:3.40.50.880 7 202 2.7E-58 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Pfam PF02540 NAD synthase 212 285 5.2E-6 T 01-11-2018 IPR022310 NAD/GMP synthase MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 SUPERFAMILY SSF52317 6 230 5.43E-64 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 SUPERFAMILY SSF52402 190 408 1.23E-62 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Pfam PF00958 GMP synthase C terminal domain 423 514 1.8E-44 T 01-11-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00097 Anthranilate synthase component II signature 55 64 1.2E-5 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00097 Anthranilate synthase component II signature 170 183 1.2E-5 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00097 Anthranilate synthase component II signature 82 93 1.2E-5 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 55 64 6.8E-8 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 6.8E-8 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 6.8E-8 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 Gene3D G3DSA:3.30.300.10 396 515 1.7E-51 T 01-11-2018 MLA2C4_01590 d79789d7879cb930b7ec6aaee0c9c684 515 SUPERFAMILY SSF54810 395 515 4.05E-51 T 01-11-2018 MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 Pfam PF00797 N-acetyltransferase 23 255 1.6E-43 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 Gene3D G3DSA:3.30.2140.20 1 255 1.7E-77 T 01-11-2018 MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 SUPERFAMILY SSF54001 3 255 1.99E-63 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 2.2E-6 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 2.2E-6 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 2.2E-6 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_14415 8630a968d6b24fa2e41590cf099a7613 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 2.2E-6 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 SUPERFAMILY SSF46785 14 90 5.92E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 SMART SM00345 21 80 5.8E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 SUPERFAMILY SSF53383 112 480 1.63E-90 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 7.2E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 7.2E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 80 1.2E-16 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 Pfam PF00155 Aminotransferase class I and II 123 474 1.4E-34 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 Gene3D G3DSA:3.40.640.10 157 375 6.8E-104 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 Gene3D G3DSA:1.10.10.10 13 105 3.1E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10125 8dcd60bb4c909bb733016ebf77d5f96e 481 Gene3D G3DSA:3.90.1150.10 112 478 6.8E-104 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_10740 c134e8fa72373ffefb7ab0ce3088674c 127 SUPERFAMILY SSF54593 1 125 8.73E-19 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_10740 c134e8fa72373ffefb7ab0ce3088674c 127 Gene3D G3DSA:3.10.180.10 1 125 1.3E-21 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_10740 c134e8fa72373ffefb7ab0ce3088674c 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 120 2.0E-7 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_00720 8495325af0f263651361c510d44e0665 87 SUPERFAMILY SSF50249 7 84 5.57E-32 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_00720 8495325af0f263651361c510d44e0665 87 Gene3D G3DSA:2.40.50.140 6 86 1.2E-35 T 01-11-2018 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 Pfam PF00366 Ribosomal protein S17 12 79 2.0E-32 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 24.115 T 01-11-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.5E-35 T 01-11-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 01-11-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 1.0E-35 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.0E-11 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.0E-11 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00720 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.0E-11 T 01-11-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 SUPERFAMILY SSF51366 1 213 4.4E-82 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 PIRSF PIRSF001461 1 214 2.3E-101 T 01-11-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 1.4E-97 T 01-11-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 01-11-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 3.8E-93 T 01-11-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 Gene3D G3DSA:3.20.20.70 1 214 4.4E-95 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_20175 0bebc4eb26e8ebc06e677fda3fc9186a 214 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 01-11-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 Gene3D G3DSA:3.40.1390.20 3 129 1.5E-44 T 01-11-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 302 1.9E-120 T 01-11-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 SUPERFAMILY SSF75138 1 131 9.16E-42 T 01-11-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.745 T 01-11-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 1.3E-77 T 01-11-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 Gene3D G3DSA:3.40.50.300 130 309 1.1E-75 T 01-11-2018 MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 Pfam PF02603 HPr Serine kinase N terminus 4 127 9.8E-42 T 01-11-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 MLA2C4_26705 b287221b963b151f4ce05c7cb29ac685 309 SUPERFAMILY SSF53795 132 298 2.69E-42 T 01-11-2018 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.3E-17 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.3E-17 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.3E-17 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.3E-17 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Gene3D G3DSA:3.40.50.800 4 550 6.9E-258 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 2.0E-56 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 562 1.5E-244 T 01-11-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 PIRSF PIRSF001535 1 566 4.3E-269 T 01-11-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Pfam PF04073 Aminoacyl-tRNA editing domain 257 374 3.6E-28 T 01-11-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 SUPERFAMILY SSF55826 218 386 1.05E-33 T 01-11-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Pfam PF03129 Anticodon binding domain 472 563 1.2E-20 T 01-11-2018 IPR004154 Anticodon-binding MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Gene3D G3DSA:3.30.930.10 11 462 6.9E-258 T 01-11-2018 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 SUPERFAMILY SSF55681 9 475 1.87E-103 T 01-11-2018 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Gene3D G3DSA:3.90.960.10 240 386 6.9E-258 T 01-11-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 41.505 T 01-11-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MLA2C4_19965 bc5cd767b344c95f76ab8842013359a3 566 SUPERFAMILY SSF52954 460 565 1.15E-30 T 01-11-2018 MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 34 212 1.5E-59 T 01-11-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 288 39.314 T 01-11-2018 IPR023705 Nucleoid occlusion protein MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 Gene3D G3DSA:1.10.10.2830 114 228 2.8E-35 T 01-11-2018 MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 SUPERFAMILY SSF110849 36 173 3.98E-35 T 01-11-2018 IPR036086 ParB/Sulfiredoxin superfamily MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 Pfam PF02195 ParB-like nuclease domain 38 126 1.1E-26 T 01-11-2018 IPR003115 ParB/Sulfiredoxin MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 SMART SM00470 37 127 3.5E-34 T 01-11-2018 IPR003115 ParB/Sulfiredoxin MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 Gene3D G3DSA:3.90.1530.30 50 113 3.4E-25 T 01-11-2018 MLA2C4_28445 724be8cfddc5731920b2aa2fc8df3d2f 290 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 35 288 4.2E-115 T 01-11-2018 IPR023705 Nucleoid occlusion protein MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 494 3.7E-208 T 01-11-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 Gene3D G3DSA:1.10.238.260 279 392 2.0E-38 T 01-11-2018 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 SMART SM00917 368 499 5.5E-32 T 01-11-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 SUPERFAMILY SSF110921 395 496 4.45E-19 T 01-11-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 Gene3D G3DSA:3.30.160.270 393 499 1.4E-10 T 01-11-2018 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 01-11-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 SUPERFAMILY SSF51569 1 290 3.37E-91 T 01-11-2018 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 506 41.35 T 01-11-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 497 4.7E-36 T 01-11-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 01-11-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 Gene3D G3DSA:3.20.20.70 1 275 9.7E-108 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_07405 f3defa6b975db0f777944c486f0b3d1d 506 Pfam PF00682 HMGL-like 4 272 3.6E-91 T 01-11-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 Pfam PF04542 Sigma-70 region 2 62 131 2.1E-18 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 PIRSF PIRSF000770 2 239 3.7E-79 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 7 239 2.7E-137 T 01-11-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 Pfam PF04545 Sigma-70, region 4 180 233 3.7E-17 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 Gene3D G3DSA:1.20.120.1810 26 131 2.2E-25 T 01-11-2018 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 6.8E-35 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 SUPERFAMILY SSF88659 143 237 4.11E-22 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 SUPERFAMILY SSF88946 24 130 4.97E-35 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 Gene3D G3DSA:1.10.10.10 168 239 1.8E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 7.1E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 7.1E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 7.1E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20405 1383dccf4175940db280ed6d43740671 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 7.1E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 Gene3D G3DSA:3.90.1310.30 62 573 1.9E-220 T 01-11-2018 MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 SUPERFAMILY SSF56601 321 692 7.72E-70 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 Gene3D G3DSA:1.10.10.1230 87 196 1.9E-220 T 01-11-2018 MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 SUPERFAMILY SSF56519 56 320 1.7E-37 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 684 2.3E-68 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 Gene3D G3DSA:3.40.710.10 320 679 1.9E-220 T 01-11-2018 MLA2C4_14080 5d8885e6726e41189f6d0c7956c61657 708 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 305 6.2E-37 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_08115 8a8bf42b65b537487a85bb0c0895c99a 56 PIRSF PIRSF036698 1 56 5.5E-37 T 01-11-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA MLA2C4_08115 8a8bf42b65b537487a85bb0c0895c99a 56 Pfam PF14084 Protein of unknown function (DUF4264) 4 56 2.6E-24 T 01-11-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA MLA2C4_01890 2998937c837258ebb5b9f161a71b0571 392 Pfam PF02374 Anion-transporting ATPase 1 302 1.5E-97 T 01-11-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MLA2C4_01890 2998937c837258ebb5b9f161a71b0571 392 Gene3D G3DSA:2.60.40.790 317 389 3.2E-21 T 01-11-2018 IPR008978 HSP20-like chaperone MLA2C4_01890 2998937c837258ebb5b9f161a71b0571 392 SUPERFAMILY SSF49764 320 386 5.13E-6 T 01-11-2018 IPR008978 HSP20-like chaperone MLA2C4_01890 2998937c837258ebb5b9f161a71b0571 392 Gene3D G3DSA:3.40.50.300 1 314 1.3E-86 T 01-11-2018 MLA2C4_01890 2998937c837258ebb5b9f161a71b0571 392 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 6 301 2.1E-85 T 01-11-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 MLA2C4_01890 2998937c837258ebb5b9f161a71b0571 392 SUPERFAMILY SSF52540 1 296 3.83E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-17 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 Gene3D G3DSA:3.40.190.290 93 286 6.6E-41 T 01-11-2018 MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 SUPERFAMILY SSF53850 91 286 2.64E-34 T 01-11-2018 MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 Pfam PF03466 LysR substrate binding domain 88 283 1.8E-37 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 Gene3D G3DSA:1.10.10.10 1 92 7.4E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09735 22572b23a3ce6c471aeab567eda4db24 289 SUPERFAMILY SSF46785 1 112 1.26E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_01920 71c0b9ae92494184226256ab727798ea 301 Gene3D G3DSA:2.60.200.40 131 286 6.6E-44 T 01-11-2018 MLA2C4_01920 71c0b9ae92494184226256ab727798ea 301 SMART SM00046 4 126 6.3E-9 T 01-11-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MLA2C4_01920 71c0b9ae92494184226256ab727798ea 301 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 127 1.7E-38 T 01-11-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MLA2C4_01920 71c0b9ae92494184226256ab727798ea 301 SUPERFAMILY SSF111331 1 296 4.32E-89 T 01-11-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MLA2C4_01920 71c0b9ae92494184226256ab727798ea 301 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 2 294 4.5E-107 T 01-11-2018 IPR005218 Diacylglycerol/lipid kinase MLA2C4_01920 71c0b9ae92494184226256ab727798ea 301 Gene3D G3DSA:3.40.50.10330 1 130 2.0E-48 T 01-11-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 Pfam PF01593 Flavin containing amine oxidoreductase 34 475 1.6E-67 T 01-11-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 Gene3D G3DSA:1.10.405.10 122 225 3.2E-97 T 01-11-2018 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 SUPERFAMILY SSF54373 316 426 4.06E-32 T 01-11-2018 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 Gene3D G3DSA:3.90.660.10 24 415 3.2E-97 T 01-11-2018 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 PRINTS PR00757 Flavin-containing amine oxidase signature 407 426 5.9E-13 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 PRINTS PR00757 Flavin-containing amine oxidase signature 457 474 5.9E-13 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 PRINTS PR00757 Flavin-containing amine oxidase signature 320 339 5.9E-13 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 PRINTS PR00757 Flavin-containing amine oxidase signature 26 45 5.9E-13 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 Gene3D G3DSA:3.50.50.60 26 425 3.2E-97 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 Gene3D G3DSA:1.10.10.1620 432 478 6.5E-19 T 01-11-2018 MLA2C4_09775 51c88b14b22a5bc78f419408a4fd42f6 478 SUPERFAMILY SSF51905 22 477 1.12E-56 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_05570 16245f43fd9cbcf5406486e3a9dbbce8 185 SMART SM00347 37 137 2.4E-17 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_05570 16245f43fd9cbcf5406486e3a9dbbce8 185 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_05570 16245f43fd9cbcf5406486e3a9dbbce8 185 Gene3D G3DSA:1.10.10.10 2 167 6.7E-44 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05570 16245f43fd9cbcf5406486e3a9dbbce8 185 Pfam PF01047 MarR family 44 101 2.4E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_05570 16245f43fd9cbcf5406486e3a9dbbce8 185 SUPERFAMILY SSF46785 19 130 7.08E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05570 16245f43fd9cbcf5406486e3a9dbbce8 185 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 2 185 49.654 T 01-11-2018 IPR023488 HTH-type transcriptional regulator Hpr MLA2C4_13415 56497b05a2195af6dd829b0faab5dc60 399 SUPERFAMILY SSF51905 121 261 3.21E-21 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_13415 56497b05a2195af6dd829b0faab5dc60 399 Gene3D G3DSA:3.50.50.60 123 261 2.1E-90 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_13415 56497b05a2195af6dd829b0faab5dc60 399 Gene3D G3DSA:3.50.50.60 8 325 2.1E-90 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_13415 56497b05a2195af6dd829b0faab5dc60 399 SUPERFAMILY SSF51905 6 156 2.39E-23 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_13415 56497b05a2195af6dd829b0faab5dc60 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 127 1.6E-7 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 SMART SM00388 85 152 3.0E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 Gene3D G3DSA:1.10.287.130 77 156 1.2E-16 T 01-11-2018 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 Gene3D G3DSA:3.30.565.10 157 309 5.2E-36 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 203 307 3.0E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 SMART SM00387 198 310 6.5E-31 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 Pfam PF00512 His Kinase A (phospho-acceptor) domain 85 152 1.8E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 SUPERFAMILY SSF55874 143 307 2.1E-39 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 SUPERFAMILY SSF47384 73 153 3.73E-15 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 235 249 9.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 288 9.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 307 9.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23585 362a58bcff330ce1f499cecd74f376a8 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 263 9.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 SUPERFAMILY SSF82866 777 995 5.36E-49 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:1.20.1640.10 493 989 4.4E-255 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 SUPERFAMILY SSF82714 183 258 4.05E-9 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:3.30.70.1320 133 319 4.4E-255 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:3.30.2090.10 686 774 4.4E-255 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 SUPERFAMILY SSF82714 688 770 6.41E-9 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:3.30.70.1440 637 831 4.4E-255 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 SUPERFAMILY SSF82693 41 132 4.39E-16 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 SUPERFAMILY SSF82866 285 483 1.31E-36 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:3.30.2090.10 177 262 4.4E-255 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 323 346 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 456 479 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 350 371 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 378 402 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 PRINTS PR00702 Acriflavin resistance protein family signature 431 454 5.5E-37 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:3.30.70.1430 41 782 4.4E-255 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:3.30.70.1430 539 636 4.4E-255 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Gene3D G3DSA:1.20.1640.10 11 492 4.4E-255 T 01-11-2018 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 Pfam PF00873 AcrB/AcrD/AcrF family 5 992 5.0E-206 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_03780 0942d4d8f3ec632cee2a2d84bf1465a4 1014 SUPERFAMILY SSF82693 156 307 2.67E-10 T 01-11-2018 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.5E-35 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.5E-35 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.5E-35 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.5E-35 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 Gene3D G3DSA:3.40.50.300 4 281 1.5E-158 T 01-11-2018 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 SUPERFAMILY SSF81271 282 363 8.94E-37 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 Gene3D G3DSA:1.10.150.300 113 200 1.5E-158 T 01-11-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 Pfam PF01926 50S ribosome-binding GTPase 5 123 9.7E-24 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 SUPERFAMILY SSF52540 3 304 1.19E-89 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 1.1E-160 T 01-11-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.241 T 01-11-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 PIRSF PIRSF006641 1 366 4.0E-167 T 01-11-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 Gene3D G3DSA:3.10.20.30 48 364 1.5E-158 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_28415 433511af2c3cb1614890a27826b9cb33 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 9.4E-41 T 01-11-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 MLA2C4_21810 edd985100d182b0b5e78908075f43bec 48 Pfam PF14174 YycC-like protein 1 47 2.7E-28 T 01-11-2018 IPR025550 YycC-like protein MLA2C4_16670 1d7afa5863507e7dcb607ddada28d211 77 Pfam PF10842 Protein of unknown function (DUF2642) 14 75 2.7E-27 T 01-11-2018 IPR020139 Protein of unknown function DUF2642 MLA2C4_16670 1d7afa5863507e7dcb607ddada28d211 77 ProDom PD058323 YUZF BH2251 8 76 6.0E-34 T 01-11-2018 IPR020139 Protein of unknown function DUF2642 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 SUPERFAMILY SSF54909 67 137 5.36E-15 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 Gene3D G3DSA:1.10.10.10 1 50 7.8E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 SMART SM00344 3 109 9.3E-38 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 01-11-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 Gene3D G3DSA:3.30.70.920 51 140 6.8E-21 T 01-11-2018 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.4E-16 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.4E-16 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.4E-16 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 9.9E-18 T 01-11-2018 MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 Pfam PF01037 Lrp/AsnC ligand binding domain 70 136 4.4E-12 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_07220 2592871f86f5d59b532627d6487adf85 150 SUPERFAMILY SSF46785 2 62 8.08E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21260 b2b34560fbf39e880fd963a9f571765f 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 12 258 1.0E-49 T 01-11-2018 MLA2C4_21260 b2b34560fbf39e880fd963a9f571765f 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 10 258 7.3E-50 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_21260 b2b34560fbf39e880fd963a9f571765f 267 Gene3D G3DSA:3.40.50.1000 11 259 6.3E-55 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_21260 b2b34560fbf39e880fd963a9f571765f 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 10 237 6.1E-28 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_21260 b2b34560fbf39e880fd963a9f571765f 267 SUPERFAMILY SSF56784 6 258 1.55E-56 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_21260 b2b34560fbf39e880fd963a9f571765f 267 Gene3D G3DSA:3.30.1240.10 88 194 6.3E-55 T 01-11-2018 MLA2C4_09385 59378f8756fabaf5ec5b41681744b773 376 Pfam PF01385 Probable transposase 170 283 2.6E-14 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_09385 59378f8756fabaf5ec5b41681744b773 376 Pfam PF12323 Helix-turn-helix domain 1 45 1.1E-11 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_09385 59378f8756fabaf5ec5b41681744b773 376 Pfam PF07282 Putative transposase DNA-binding domain 300 372 1.0E-18 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_09385 59378f8756fabaf5ec5b41681744b773 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 250 324 1.2E-8 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_14455 4f59bef781b2fa65ea77e6934e42b0e3 492 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 12 474 8.9E-146 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_14455 4f59bef781b2fa65ea77e6934e42b0e3 492 PIRSF PIRSF005690 1 489 6.5E-159 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_10795 79d4d5e89226c7c40a1214eed5eeb43c 742 SMART SM00460 472 549 4.5E-20 T 01-11-2018 IPR002931 Transglutaminase-like MLA2C4_10795 79d4d5e89226c7c40a1214eed5eeb43c 742 Pfam PF13559 Domain of unknown function (DUF4129) 657 723 3.7E-5 T 01-11-2018 IPR025403 Domain of unknown function DUF4129 MLA2C4_10795 79d4d5e89226c7c40a1214eed5eeb43c 742 SUPERFAMILY SSF54001 359 664 2.94E-53 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_10795 79d4d5e89226c7c40a1214eed5eeb43c 742 Pfam PF01841 Transglutaminase-like superfamily 423 547 2.1E-26 T 01-11-2018 IPR002931 Transglutaminase-like MLA2C4_10795 79d4d5e89226c7c40a1214eed5eeb43c 742 Gene3D G3DSA:3.10.620.30 374 559 2.0E-24 T 01-11-2018 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 9.7E-25 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 9.7E-25 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 9.7E-25 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 9.7E-25 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 SUPERFAMILY SSF161070 4 487 4.58E-142 T 01-11-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 Pfam PF00209 Sodium:neurotransmitter symporter family 124 487 1.1E-77 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_21305 5108cfa058534da59beb9ca99e47846b 508 Pfam PF00209 Sodium:neurotransmitter symporter family 4 122 5.7E-38 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 SUPERFAMILY SSF88659 106 178 5.42E-13 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 Pfam PF04542 Sigma-70 region 2 24 94 1.7E-11 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 Pfam PF08281 Sigma-70, region 4 121 174 6.6E-15 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 Gene3D G3DSA:1.10.10.10 102 180 8.9E-16 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 SUPERFAMILY SSF88946 4 112 6.8E-18 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 Gene3D G3DSA:1.10.1740.10 5 90 2.4E-15 T 01-11-2018 MLA2C4_08930 6b449a6d09f0c60e0a36c13f4bebde9a 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 177 3.3E-27 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 SUPERFAMILY SSF52374 4 316 1.29E-113 T 01-11-2018 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 Gene3D G3DSA:1.10.10.350 390 485 8.4E-32 T 01-11-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 34.004 T 01-11-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 SUPERFAMILY SSF48163 298 483 1.7E-48 T 01-11-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 5.0E-123 T 01-11-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 Gene3D G3DSA:3.40.50.620 1 332 5.0E-142 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 2.8E-29 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.8E-29 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.8E-29 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 2.8E-29 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 2.8E-29 T 01-11-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00555 d96fa3b7d8c3570404bb5a7b2972e295 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 482 9.2E-191 T 01-11-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MLA2C4_26665 0d04537310bc86fce3d79cd0a44f41ea 293 SUPERFAMILY SSF52540 4 162 1.01E-12 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26665 0d04537310bc86fce3d79cd0a44f41ea 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 289 42.517 T 01-11-2018 IPR005337 RapZ-like family GO:0005524 MLA2C4_26665 0d04537310bc86fce3d79cd0a44f41ea 293 PIRSF PIRSF005052 7 292 5.8E-109 T 01-11-2018 IPR005337 RapZ-like family GO:0005524 MLA2C4_26665 0d04537310bc86fce3d79cd0a44f41ea 293 Gene3D G3DSA:3.40.50.300 2 175 5.7E-5 T 01-11-2018 MLA2C4_26665 0d04537310bc86fce3d79cd0a44f41ea 293 Pfam PF03668 P-loop ATPase protein family 7 290 1.2E-123 T 01-11-2018 IPR005337 RapZ-like family GO:0005524 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 295 5.2E-157 T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 SUPERFAMILY SSF51366 19 267 2.97E-69 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 PIRSF PIRSF029271 1 295 9.6E-155 T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 Gene3D G3DSA:3.20.20.70 2 295 9.0E-148 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 Pfam PF01680 SOR/SNZ family 8 213 2.7E-106 T 01-11-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00075 621ad26067e6e9216890f45a5d3af442 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 55.002 T 01-11-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_24110 1b071d0669aa3505026e4950f85be119 131 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 30 113 2.2E-29 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_24110 1b071d0669aa3505026e4950f85be119 131 PIRSF PIRSF021377 1 130 1.4E-54 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_24110 1b071d0669aa3505026e4950f85be119 131 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 2 122 3.4E-50 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 Gene3D G3DSA:3.90.1150.10 115 473 7.5E-98 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.2E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.2E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 Gene3D G3DSA:3.40.640.10 153 372 7.5E-98 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 Gene3D G3DSA:1.10.10.10 6 86 1.2E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 9.5E-14 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 SUPERFAMILY SSF53383 109 478 2.75E-84 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 Pfam PF00155 Aminotransferase class I and II 146 470 2.2E-29 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 SUPERFAMILY SSF46785 7 80 1.1E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_13880 ad0b3c627af6c206273dae7b16da3d61 482 SMART SM00345 17 76 3.6E-13 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_16500 5944232ac9357a1e41d92e9168dbabdd 214 Gene3D G3DSA:3.40.50.850 2 204 3.9E-47 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_16500 5944232ac9357a1e41d92e9168dbabdd 214 Pfam PF00857 Isochorismatase family 12 163 2.6E-24 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_16500 5944232ac9357a1e41d92e9168dbabdd 214 SUPERFAMILY SSF52499 3 204 4.19E-49 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 Pfam PF00271 Helicase conserved C-terminal domain 397 464 2.7E-6 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 SUPERFAMILY SSF52540 26 233 1.89E-27 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 SMART SM00487 69 253 1.8E-14 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 Gene3D G3DSA:3.40.50.300 62 241 4.2E-28 T 01-11-2018 MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 SUPERFAMILY SSF52540 87 491 4.34E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 Pfam PF04851 Type III restriction enzyme, res subunit 86 215 2.1E-11 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MLA2C4_12855 32383292ae1709cc8af04186bfb2c82c 525 SMART SM00490 324 466 9.7E-4 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Gene3D G3DSA:3.40.50.300 763 967 7.5E-49 T 01-11-2018 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Gene3D G3DSA:3.40.50.300 479 762 7.6E-60 T 01-11-2018 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1058 1231 3.9E-11 T 01-11-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 11 1239 20.1 T 01-11-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Gene3D G3DSA:3.40.50.300 6 211 1.8E-40 T 01-11-2018 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Gene3D G3DSA:3.40.50.300 352 478 3.7E-31 T 01-11-2018 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 SUPERFAMILY SSF52980 1018 1233 1.45E-39 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 465 7.5E-82 T 01-11-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Pfam PF13361 UvrD-like helicase C-terminal domain 476 889 1.2E-30 T 01-11-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 13 1238 0.0 T 01-11-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 SUPERFAMILY SSF52540 7 893 1.89E-116 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05995 594661ed80af534afa298eb9fac6f90f 1241 Gene3D G3DSA:3.90.320.10 998 1239 5.8E-80 T 01-11-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal MLA2C4_27375 fa5f9aa02955d87ea997b4ada95e06d7 236 Gene3D G3DSA:3.30.360.40 163 236 1.5E-27 T 01-11-2018 MLA2C4_27375 fa5f9aa02955d87ea997b4ada95e06d7 236 SUPERFAMILY SSF143842 32 233 7.72E-52 T 01-11-2018 IPR036209 YwmB-like superfamily MLA2C4_27375 fa5f9aa02955d87ea997b4ada95e06d7 236 Gene3D G3DSA:3.30.2030.10 32 162 7.7E-19 T 01-11-2018 MLA2C4_27375 fa5f9aa02955d87ea997b4ada95e06d7 236 Pfam PF08680 TATA-box binding 48 236 3.7E-46 T 01-11-2018 IPR014794 TATA-box binding MLA2C4_16555 8c9ac6f684fb132df57027b171d94658 68 Gene3D G3DSA:3.40.1350.10 7 61 1.1E-7 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MLA2C4_16555 8c9ac6f684fb132df57027b171d94658 68 SUPERFAMILY SSF52980 8 47 1.45E-5 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MLA2C4_16555 8c9ac6f684fb132df57027b171d94658 68 Pfam PF03838 Recombination protein U 6 52 5.4E-7 T 01-11-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PIRSF PIRSF001415 1 326 3.8E-155 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 SUPERFAMILY SSF51569 5 325 5.98E-145 T 01-11-2018 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 SMART SM01004 4 323 5.3E-242 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 322 2.3E-151 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 1.2E-59 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 1.2E-59 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 1.2E-59 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.2E-59 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 1.2E-59 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.2E-59 T 01-11-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 Gene3D G3DSA:3.20.20.70 2 324 8.6E-150 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_23260 ed29a9b64e6160a27a3093f75fe266d1 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 01-11-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MLA2C4_12295 cd082c1b99d4780edc6c41976beff204 428 SUPERFAMILY SSF103473 17 420 6.1E-33 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_12295 cd082c1b99d4780edc6c41976beff204 428 Gene3D G3DSA:1.20.1250.20 11 412 9.9E-31 T 01-11-2018 MLA2C4_12295 cd082c1b99d4780edc6c41976beff204 428 Pfam PF07690 Major Facilitator Superfamily 25 368 1.3E-20 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_27930 67ba839bf24f15c52136fa0b54835497 140 Gene3D G3DSA:1.10.10.2520 8 92 1.9E-10 T 01-11-2018 MLA2C4_27930 67ba839bf24f15c52136fa0b54835497 140 Pfam PF07486 Cell Wall Hydrolase 24 129 6.2E-18 T 01-11-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 MLA2C4_24480 7abd7772c6861c020982ba264529724f 550 Pfam PF01943 Polysaccharide biosynthesis protein 6 320 4.6E-45 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_24480 7abd7772c6861c020982ba264529724f 550 PIRSF PIRSF038958 1 537 1.3E-122 T 01-11-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type MLA2C4_24480 7abd7772c6861c020982ba264529724f 550 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 372 519 5.1E-30 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 152 1.3E-43 T 01-11-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 166 275 2.5E-24 T 01-11-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 Gene3D G3DSA:1.10.1040.10 166 296 1.0E-49 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 Gene3D G3DSA:3.40.50.720 1 165 1.4E-51 T 01-11-2018 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 234 246 - T 01-11-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 SUPERFAMILY SSF51735 1 152 6.26E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 155 183 6.5E-26 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 58 87 6.5E-26 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 230 257 6.5E-26 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 22 6.5E-26 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 297 6.4E-148 T 01-11-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 SUPERFAMILY SSF48179 164 296 2.79E-40 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_17725 8d5e3fbce7a13e3281ac7e88c5b9b1eb 297 SMART SM01350 166 297 2.9E-6 T 01-11-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 SUPERFAMILY SSF52540 77 375 2.55E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 372 2.4E-27 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Gene3D G3DSA:3.30.1360.120 1 123 6.7E-45 T 01-11-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Gene3D G3DSA:3.40.50.300 221 386 3.6E-107 T 01-11-2018 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Pfam PF12631 MnmE helical domain 126 455 6.4E-60 T 01-11-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 123 6.0E-39 T 01-11-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 SUPERFAMILY SSF116878 124 458 1.12E-50 T 01-11-2018 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Pfam PF01926 50S ribosome-binding GTPase 224 335 8.2E-26 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 458 34.091 T 01-11-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 458 1.7E-130 T 01-11-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MLA2C4_28460 f0a2afdd17eeb48e6969b6fa3908d2ec 458 Gene3D G3DSA:1.20.120.430 124 458 3.6E-107 T 01-11-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 MLA2C4_03335 3cff8b5c6aeccd7b745412f292646178 368 Pfam PF03845 Spore germination protein 7 319 1.4E-57 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_03335 3cff8b5c6aeccd7b745412f292646178 368 Gene3D G3DSA:1.20.1740.10 2 367 2.0E-10 T 01-11-2018 MLA2C4_03335 3cff8b5c6aeccd7b745412f292646178 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 360 4.9E-56 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Gene3D G3DSA:1.10.150.20 85 150 1.9E-19 T 01-11-2018 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SMART SM00481 338 417 1.5E-21 T 01-11-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Gene3D G3DSA:3.30.210.10 261 326 1.9E-18 T 01-11-2018 IPR037160 DNA polymerase, thumb domain superfamily MLA2C4_23655 e18c8691f84460f145424513ef809734 572 PIRSF PIRSF005047 3 572 5.0E-242 T 01-11-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SUPERFAMILY SSF47802 2 79 7.19E-20 T 01-11-2018 IPR027421 DNA polymerase lambda lyase domain superfamily MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SMART SM00278 90 109 56.0 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SMART SM00278 50 69 5.8 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SMART SM00278 125 144 6.8 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Pfam PF14520 Helix-hairpin-helix domain 92 145 2.5E-6 T 01-11-2018 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Pfam PF02811 PHP domain 339 466 3.5E-10 T 01-11-2018 IPR004013 PHP domain GO:0003824 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Pfam PF14791 DNA polymerase beta thumb 255 316 3.2E-19 T 01-11-2018 IPR029398 DNA polymerase beta, thumb domain MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Gene3D G3DSA:1.10.150.110 1 84 1.2E-19 T 01-11-2018 IPR027421 DNA polymerase lambda lyase domain superfamily MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SUPERFAMILY SSF89550 338 567 1.44E-56 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Gene3D G3DSA:3.30.460.10 154 260 4.3E-23 T 01-11-2018 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Pfam PF14716 Helix-hairpin-helix domain 6 71 8.7E-20 T 01-11-2018 IPR010996 DNA polymerase beta-like, N-terminal domain MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SMART SM00483 2 316 4.2E-84 T 01-11-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 Gene3D G3DSA:3.20.20.140 327 572 6.4E-78 T 01-11-2018 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SUPERFAMILY SSF81301 154 316 1.24E-45 T 01-11-2018 MLA2C4_23655 e18c8691f84460f145424513ef809734 572 SUPERFAMILY SSF158702 48 145 1.78E-8 T 01-11-2018 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 295 4.7E-88 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 Gene3D G3DSA:3.30.1490.20 109 175 1.7E-75 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 SUPERFAMILY SSF56059 94 293 6.27E-48 T 01-11-2018 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 Pfam PF07478 D-ala D-ala ligase C-terminus 104 293 9.7E-51 T 01-11-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 296 35.339 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 SUPERFAMILY SSF52440 1 94 5.56E-28 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 61 72 - T 01-11-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 PIRSF PIRSF039102 41 303 8.6E-100 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 PIRSF PIRSF039102 1 50 2.8E-11 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 Gene3D G3DSA:3.30.470.20 94 289 1.7E-75 T 01-11-2018 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 Gene3D G3DSA:3.40.50.20 1 82 2.6E-32 T 01-11-2018 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 239 266 - T 01-11-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 SMART SM01209 93 263 0.0022 T 01-11-2018 MLA2C4_13885 65076f864b5f7d1b9b504397db5cd6a3 304 Pfam PF01820 D-ala D-ala ligase N-terminus 2 84 6.5E-22 T 01-11-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Gene3D G3DSA:3.40.50.300 718 926 2.9E-44 T 01-11-2018 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 930 7.0E-269 T 01-11-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 1 932 28.127 T 01-11-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 SMART SM00479 4 172 1.5E-46 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 SUPERFAMILY SSF52540 273 894 5.02E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 SMART SM00487 255 523 0.0073 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Pfam PF13307 Helicase C-terminal domain 748 912 3.1E-41 T 01-11-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 167 2.2E-28 T 01-11-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Pfam PF00929 Exonuclease 6 163 1.2E-31 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Gene3D G3DSA:3.30.420.10 1 172 8.5E-51 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 SMART SM00491 766 900 1.9E-31 T 01-11-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Pfam PF04851 Type III restriction enzyme, res subunit 257 482 3.5E-6 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 SUPERFAMILY SSF53098 4 209 5.06E-54 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_08110 ab27bdb2ed378b306c7d9149047567e1 934 Gene3D G3DSA:3.40.50.300 257 521 1.8E-45 T 01-11-2018 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 642 5.8E-238 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 SUPERFAMILY SSF55681 247 536 8.09E-95 T 01-11-2018 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Gene3D G3DSA:3.30.54.20 135 191 1.3E-62 T 01-11-2018 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 SUPERFAMILY SSF52954 537 640 1.45E-31 T 01-11-2018 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 3.1E-16 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 SMART SM00863 174 223 1.2E-25 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Gene3D G3DSA:3.30.930.10 229 542 4.7E-116 T 01-11-2018 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 SUPERFAMILY SSF81271 5 64 5.89E-17 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Gene3D G3DSA:3.30.980.10 73 226 1.3E-62 T 01-11-2018 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Gene3D G3DSA:3.40.50.800 543 645 3.7E-34 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 SUPERFAMILY SSF55186 66 245 4.06E-64 T 01-11-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 645 35.112 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Gene3D G3DSA:3.10.20.30 3 65 6.4E-26 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 474 502 3.3E-47 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 335 363 3.3E-47 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 544 556 3.3E-47 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 517 530 3.3E-47 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 368 391 3.3E-47 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Pfam PF02824 TGS domain 5 64 5.3E-12 T 01-11-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 328 539 2.9E-34 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23775 94654cf8ecb96ed548157d7e61c09881 645 Pfam PF03129 Anticodon binding domain 551 640 6.5E-25 T 01-11-2018 IPR004154 Anticodon-binding MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 Gene3D G3DSA:3.30.1160.10 81 149 6.2E-27 T 01-11-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 TIGRFAM TIGR00673 cynS: cyanase 6 149 4.6E-45 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 Hamap MF_00535 Cyanate hydratase [cynS]. 1 149 66.305 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 SUPERFAMILY SSF55234 79 149 2.48E-22 T 01-11-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 Gene3D G3DSA:1.10.260.40 1 78 7.6E-28 T 01-11-2018 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 SUPERFAMILY SSF47413 1 75 2.43E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 Pfam PF02560 Cyanate lyase C-terminal domain 79 147 4.6E-27 T 01-11-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 PRINTS PR01693 Cyanase signature 134 144 2.9E-23 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 PRINTS PR01693 Cyanase signature 101 117 2.9E-23 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 PRINTS PR01693 Cyanase signature 14 29 2.9E-23 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 PRINTS PR01693 Cyanase signature 34 51 2.9E-23 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 PRINTS PR01693 Cyanase signature 83 97 2.9E-23 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 PIRSF PIRSF001263 1 149 7.1E-45 T 01-11-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_26470 a47d8bd26b6b67447e2b0992ab803bad 149 SMART SM01116 75 149 3.8E-31 T 01-11-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 MLA2C4_00820 81508eadadf4e8486d964d9e4190750f 280 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_00820 81508eadadf4e8486d964d9e4190750f 280 SMART SM00382 32 218 2.7E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00820 81508eadadf4e8486d964d9e4190750f 280 Pfam PF00005 ABC transporter 23 170 1.5E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_00820 81508eadadf4e8486d964d9e4190750f 280 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 274 6.5E-120 T 01-11-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 MLA2C4_00820 81508eadadf4e8486d964d9e4190750f 280 SUPERFAMILY SSF52540 6 232 2.48E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00820 81508eadadf4e8486d964d9e4190750f 280 Gene3D G3DSA:3.40.50.300 2 280 1.3E-80 T 01-11-2018 MLA2C4_02055 65cfc3c1fe00641e1192ddb0e4a7951e 335 SUPERFAMILY SSF81345 5 333 1.2E-78 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_02055 65cfc3c1fe00641e1192ddb0e4a7951e 335 Gene3D G3DSA:1.10.3470.10 6 335 7.0E-91 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_02055 65cfc3c1fe00641e1192ddb0e4a7951e 335 PRINTS PR00173 Glutamate-aspartate symporter signature 55 75 1.2E-7 T 01-11-2018 MLA2C4_02055 65cfc3c1fe00641e1192ddb0e4a7951e 335 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.2E-7 T 01-11-2018 MLA2C4_02055 65cfc3c1fe00641e1192ddb0e4a7951e 335 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 1.2E-7 T 01-11-2018 MLA2C4_02055 65cfc3c1fe00641e1192ddb0e4a7951e 335 Pfam PF01032 FecCD transport family 20 333 5.3E-88 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_06995 c7d2443873f7de5718642c37ab30b60d 361 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 9 359 4.4E-137 T 01-11-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 MLA2C4_06995 c7d2443873f7de5718642c37ab30b60d 361 SUPERFAMILY SSF53474 56 357 4.65E-35 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_06995 c7d2443873f7de5718642c37ab30b60d 361 Pfam PF00561 alpha/beta hydrolase fold 71 338 1.2E-18 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_06995 c7d2443873f7de5718642c37ab30b60d 361 Gene3D G3DSA:3.40.50.1820 52 360 1.9E-24 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_17815 891de28a6574bfa1262a01aab576b73c 499 Gene3D G3DSA:3.30.300.310 399 498 7.4E-31 T 01-11-2018 MLA2C4_17815 891de28a6574bfa1262a01aab576b73c 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_17815 891de28a6574bfa1262a01aab576b73c 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 486 1.3E-17 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_17815 891de28a6574bfa1262a01aab576b73c 499 SUPERFAMILY SSF56801 2 494 1.26E-135 T 01-11-2018 MLA2C4_17815 891de28a6574bfa1262a01aab576b73c 499 Gene3D G3DSA:3.40.50.12780 1 396 4.2E-106 T 01-11-2018 MLA2C4_17815 891de28a6574bfa1262a01aab576b73c 499 Pfam PF00501 AMP-binding enzyme 9 403 1.5E-95 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 90 6.0E-44 T 01-11-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 Gene3D G3DSA:2.40.40.20 1 123 2.2E-54 T 01-11-2018 MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 SUPERFAMILY SSF50692 1 120 4.47E-51 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 8.1E-57 T 01-11-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 Pfam PF02261 Aspartate decarboxylase 1 114 1.7E-53 T 01-11-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 73.171 T 01-11-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MLA2C4_08105 3c0c577527bee68e1f02c8cbdecba846 127 PIRSF PIRSF006246 1 126 2.6E-55 T 01-11-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Gene3D G3DSA:3.40.50.10810 582 824 2.3E-60 T 01-11-2018 IPR038718 SNF2-like, N-terminal domain superfamily MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Pfam PF00176 SNF2 family N-terminal domain 625 886 5.5E-49 T 01-11-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Gene3D G3DSA:3.40.50.300 825 1022 5.4E-85 T 01-11-2018 MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Gene3D G3DSA:1.20.120.850 836 1058 5.4E-85 T 01-11-2018 MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Pfam PF00271 Helicase conserved C-terminal domain 897 1008 3.7E-22 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 SMART SM00487 609 795 3.5E-29 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 SUPERFAMILY SSF52540 591 814 4.98E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Pfam PF04434 SWIM zinc finger 53 91 7.2E-5 T 01-11-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 Pfam PF08455 Bacterial SNF2 helicase associated 235 606 2.0E-83 T 01-11-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 SMART SM00490 926 1008 1.7E-24 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_09165 e5f2d128be9aa4e1badbe34ea4419fc7 1064 SUPERFAMILY SSF52540 816 1063 2.88E-68 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22615 cb37887776645d322f39b2f2d99e9e5f 189 SMART SM00471 14 141 4.7E-9 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_22615 cb37887776645d322f39b2f2d99e9e5f 189 Pfam PF01966 HD domain 18 130 7.2E-15 T 01-11-2018 IPR006674 HD domain MLA2C4_22615 cb37887776645d322f39b2f2d99e9e5f 189 TIGRFAM TIGR00277 HDIG: HDIG domain 15 109 2.2E-8 T 01-11-2018 IPR006675 HDIG domain MLA2C4_22615 cb37887776645d322f39b2f2d99e9e5f 189 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 1.1E-63 T 01-11-2018 IPR005249 Conserved hypothetical protein CHP00488 MLA2C4_22615 cb37887776645d322f39b2f2d99e9e5f 189 SUPERFAMILY SSF109604 5 181 8.79E-38 T 01-11-2018 MLA2C4_22615 cb37887776645d322f39b2f2d99e9e5f 189 Gene3D G3DSA:1.10.3210.10 1 186 2.3E-59 T 01-11-2018 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 SMART SM00387 417 525 8.6E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Gene3D G3DSA:3.30.450.20 33 169 1.4E-27 T 01-11-2018 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 SUPERFAMILY SSF55874 394 522 3.14E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Gene3D G3DSA:3.30.565.10 384 527 2.0E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 524 7.5E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 320 366 2.8E-9 T 01-11-2018 IPR039506 SpoOB, alpha-helical domain MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 SMART SM00091 218 283 9.7E-5 T 01-11-2018 IPR000014 PAS domain MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 SUPERFAMILY SSF55785 218 309 5.23E-8 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Gene3D G3DSA:3.30.450.20 204 312 9.9E-23 T 01-11-2018 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 7.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 470 7.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 7.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 484 7.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 SUPERFAMILY SSF103190 42 172 1.37E-25 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Pfam PF13188 PAS domain 223 274 1.8E-4 T 01-11-2018 IPR000014 PAS domain MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 Pfam PF17203 Single cache domain 3 40 170 4.0E-15 T 01-11-2018 IPR033463 Single cache domain 3 MLA2C4_04915 dfd650b70ce1e7585799ce9d6bf92cca 529 SUPERFAMILY SSF55890 324 370 2.22E-9 T 01-11-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 MLA2C4_17015 2a2d6dc239ac917ebc882846a798a754 354 Pfam PF02687 FtsX-like permease family 261 344 3.9E-6 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_08340 f8b08f34557398cdad055273e855efed 128 SUPERFAMILY SSF53098 2 122 3.29E-32 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_08340 f8b08f34557398cdad055273e855efed 128 Pfam PF13456 Reverse transcriptase-like 7 124 5.9E-20 T 01-11-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MLA2C4_08340 f8b08f34557398cdad055273e855efed 128 Gene3D G3DSA:3.30.420.10 2 128 1.7E-30 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_09485 a7d34f2a62368f835bf8839ee601a30d 283 Gene3D G3DSA:1.10.1780.10 1 138 2.4E-7 T 01-11-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MLA2C4_09485 a7d34f2a62368f835bf8839ee601a30d 283 SUPERFAMILY SSF81923 5 130 5.49E-7 T 01-11-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MLA2C4_09485 a7d34f2a62368f835bf8839ee601a30d 283 Gene3D G3DSA:3.40.630.30 151 273 4.1E-13 T 01-11-2018 MLA2C4_09485 a7d34f2a62368f835bf8839ee601a30d 283 Pfam PF00583 Acetyltransferase (GNAT) family 167 272 1.3E-6 T 01-11-2018 IPR000182 GNAT domain MLA2C4_09485 a7d34f2a62368f835bf8839ee601a30d 283 SUPERFAMILY SSF55729 158 272 2.88E-16 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 Gene3D G3DSA:3.30.9.10 102 343 2.2E-134 T 01-11-2018 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 SUPERFAMILY SSF54373 249 342 5.76E-11 T 01-11-2018 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 531 2.2E-21 T 01-11-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 SUPERFAMILY SSF51905 16 237 6.64E-33 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 8.5E-31 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 336 342 8.5E-31 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 366 378 8.5E-31 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 8.5E-31 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 8.5E-31 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 8.5E-31 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 Gene3D G3DSA:1.10.8.870 421 551 8.4E-39 T 01-11-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 371 381 - T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 Pfam PF01266 FAD dependent oxidoreductase 21 344 4.4E-51 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_05515 c4a9590e28e6b19474ff9c607a70de40 560 Gene3D G3DSA:3.50.50.60 18 379 2.2E-134 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_17340 e946a867e6784ec143a57f8ee310baa0 273 Gene3D G3DSA:3.10.20.490 173 273 4.0E-11 T 01-11-2018 MLA2C4_17340 e946a867e6784ec143a57f8ee310baa0 273 Pfam PF14478 Domain of unknown function (DUF4430) 201 271 5.4E-16 T 01-11-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 SMART SM00984 327 429 1.0E-38 T 01-11-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 SUPERFAMILY SSF52413 316 440 2.49E-29 T 01-11-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 SUPERFAMILY SSF48179 213 307 8.16E-34 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 327 427 1.9E-24 T 01-11-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 PIRSF PIRSF500134 16 447 2.2E-163 T 01-11-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 SUPERFAMILY SSF51735 16 203 2.03E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 Gene3D G3DSA:3.40.50.720 10 212 5.0E-68 T 01-11-2018 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 16 198 1.5E-59 T 01-11-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 213 305 2.1E-39 T 01-11-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 Gene3D G3DSA:3.40.50.720 244 454 1.2E-65 T 01-11-2018 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 16 425 2.4E-131 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 Gene3D G3DSA:1.20.5.100 213 243 2.7E-19 T 01-11-2018 MLA2C4_26900 08680574527d3adbfc2a0b245b46619f 456 PIRSF PIRSF000124 16 444 1.2E-150 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MLA2C4_19895 8614d4bed036111459626df8792bd529 413 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 4.6E-51 T 01-11-2018 IPR011765 Peptidase M16, N-terminal MLA2C4_19895 8614d4bed036111459626df8792bd529 413 SUPERFAMILY SSF63411 228 401 5.65E-46 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_19895 8614d4bed036111459626df8792bd529 413 Gene3D G3DSA:3.30.830.10 1 215 2.9E-82 T 01-11-2018 MLA2C4_19895 8614d4bed036111459626df8792bd529 413 SUPERFAMILY SSF63411 3 204 2.55E-64 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_19895 8614d4bed036111459626df8792bd529 413 Gene3D G3DSA:3.30.830.10 218 412 1.1E-55 T 01-11-2018 MLA2C4_19895 8614d4bed036111459626df8792bd529 413 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 01-11-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MLA2C4_19895 8614d4bed036111459626df8792bd529 413 Pfam PF05193 Peptidase M16 inactive domain 166 338 1.5E-41 T 01-11-2018 IPR007863 Peptidase M16, C-terminal MLA2C4_12030 1ff86fd38c01b391f432eba9677b02b6 283 Gene3D G3DSA:3.10.50.40 124 256 1.1E-34 T 01-11-2018 MLA2C4_12030 1ff86fd38c01b391f432eba9677b02b6 283 SUPERFAMILY SSF54534 127 222 1.11E-30 T 01-11-2018 MLA2C4_12030 1ff86fd38c01b391f432eba9677b02b6 283 SUPERFAMILY SSF109998 47 162 1.63E-12 T 01-11-2018 IPR027304 Trigger factor/SurA domain superfamily MLA2C4_12030 1ff86fd38c01b391f432eba9677b02b6 283 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 281 21.871 T 01-11-2018 IPR023059 Foldase protein PrsA GO:0003755 MLA2C4_12030 1ff86fd38c01b391f432eba9677b02b6 283 Pfam PF13616 PPIC-type PPIASE domain 131 224 1.0E-27 T 01-11-2018 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 507 648 5.0E-35 T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 Gene3D G3DSA:3.40.50.2300 1 104 1.3E-41 T 01-11-2018 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 SUPERFAMILY SSF52794 2 103 2.79E-37 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 508 633 3.6E-41 T 01-11-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 Gene3D G3DSA:3.40.930.10 497 649 1.1E-41 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 111 458 2.3E-98 T 01-11-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 SUPERFAMILY SSF55804 501 648 3.53E-37 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 Pfam PF02378 Phosphotransferase system, EIIC 128 403 1.1E-21 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 551 567 - T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 86 4.4E-31 T 01-11-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 MLA2C4_27215 77c604d53237d247bcf0c165154e6127 650 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 8.6E-18 T 01-11-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MLA2C4_27285 558873a18328a4457501f01b4eda9d17 314 SUPERFAMILY SSF51735 3 307 2.01E-79 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_27285 558873a18328a4457501f01b4eda9d17 314 Gene3D G3DSA:3.40.50.720 7 295 1.8E-113 T 01-11-2018 MLA2C4_27285 558873a18328a4457501f01b4eda9d17 314 Gene3D G3DSA:3.90.25.10 169 304 1.8E-113 T 01-11-2018 MLA2C4_27285 558873a18328a4457501f01b4eda9d17 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 238 4.3E-79 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_27285 558873a18328a4457501f01b4eda9d17 314 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 4 306 50.835 T 01-11-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 SUPERFAMILY SSF46785 17 61 4.45E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 SMART SM00382 103 252 4.8E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Gene3D G3DSA:3.40.50.510 535 668 2.2E-37 T 01-11-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Pfam PF00874 PRD domain 799 884 3.3E-14 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Pfam PF00874 PRD domain 443 528 2.3E-20 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 SUPERFAMILY SSF52540 98 322 3.99E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Pfam PF03610 PTS system fructose IIA component 541 653 6.4E-8 T 01-11-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 SUPERFAMILY SSF53062 539 660 5.76E-20 T 01-11-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Pfam PF00158 Sigma-54 interaction domain 83 244 5.2E-45 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 175 190 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Gene3D G3DSA:3.40.50.300 67 255 1.5E-39 T 01-11-2018 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 SUPERFAMILY SSF63520 792 885 1.1E-15 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Gene3D G3DSA:1.10.1790.10 791 887 5.1E-8 T 01-11-2018 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 Gene3D G3DSA:1.10.1790.10 433 530 1.4E-23 T 01-11-2018 MLA2C4_26915 7e1c03974c37e048f2b575934510c620 891 SUPERFAMILY SSF63520 428 528 4.45E-23 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SUPERFAMILY SSF52440 548 668 6.04E-49 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Pfam PF02142 MGS-like domain 950 1036 8.5E-19 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SMART SM01096 420 540 8.9E-64 T 01-11-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SUPERFAMILY SSF52440 1 127 2.01E-49 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-62 T 01-11-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SUPERFAMILY SSF48108 395 547 1.03E-48 T 01-11-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SMART SM01209 674 837 0.0054 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Gene3D G3DSA:3.30.470.20 120 401 3.0E-124 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SUPERFAMILY SSF56059 666 927 9.6E-102 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.133 T 01-11-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1064 13.47 T 01-11-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 01-11-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Gene3D G3DSA:3.40.50.20 1 116 1.7E-48 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Gene3D G3DSA:3.40.50.1380 930 1066 6.7E-37 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Gene3D G3DSA:3.40.50.20 547 655 9.6E-47 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Gene3D G3DSA:1.10.1030.10 404 546 1.3E-42 T 01-11-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 9.5E-41 T 01-11-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Gene3D G3DSA:3.30.470.20 659 929 4.2E-108 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.7E-81 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 3.7E-39 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SUPERFAMILY SSF52335 936 1068 5.49E-32 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SUPERFAMILY SSF56059 128 399 6.89E-109 T 01-11-2018 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_20315 f3213d5b9583aa281527377b37bf04b8 1072 SMART SM00851 949 1036 4.2E-26 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Gene3D G3DSA:2.40.50.140 96 180 3.9E-12 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SUPERFAMILY SSF50249 5 107 2.69E-19 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Gene3D G3DSA:2.40.50.140 3 95 3.1E-18 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Pfam PF00575 S1 RNA binding domain 100 168 8.5E-15 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Pfam PF00575 S1 RNA binding domain 271 343 1.5E-23 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Pfam PF00575 S1 RNA binding domain 15 82 4.2E-14 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Pfam PF00575 S1 RNA binding domain 186 257 9.2E-26 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 82 101 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 18 36 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 209 230 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 36 50 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 152 172 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 326 344 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 106 122 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 123 140 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 PRINTS PR00681 Ribosomal protein S1 signature 287 306 5.5E-56 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SMART SM00316 101 168 1.0E-9 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SMART SM00316 16 85 4.1E-14 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SMART SM00316 187 257 1.0E-28 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SMART SM00316 272 343 9.3E-26 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SUPERFAMILY SSF50249 259 347 2.54E-24 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Gene3D G3DSA:2.40.50.140 264 347 1.9E-26 T 01-11-2018 MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SUPERFAMILY SSF50249 186 270 7.86E-28 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 SUPERFAMILY SSF50249 88 170 4.03E-16 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_07885 ee7512bfdec22e48edf856c5faf87d5a 382 Gene3D G3DSA:2.40.50.140 184 263 3.2E-31 T 01-11-2018 MLA2C4_23960 be4e708dadab8dfb161ae5a19259790b 227 Gene3D G3DSA:3.60.15.10 1 227 5.1E-77 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_23960 be4e708dadab8dfb161ae5a19259790b 227 Pfam PF13483 Beta-lactamase superfamily domain 2 193 9.3E-29 T 01-11-2018 MLA2C4_23960 be4e708dadab8dfb161ae5a19259790b 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 38.474 T 01-11-2018 IPR022877 Protein of unknown funcion UPF0173 MLA2C4_23960 be4e708dadab8dfb161ae5a19259790b 227 SMART SM00849 7 193 1.9E-13 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_23960 be4e708dadab8dfb161ae5a19259790b 227 SUPERFAMILY SSF56281 1 220 7.99E-43 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 Gene3D G3DSA:3.40.50.10860 5 260 7.0E-99 T 01-11-2018 MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 6.2E-32 T 01-11-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 SUPERFAMILY SSF53223 3 101 2.07E-36 T 01-11-2018 MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 SUPERFAMILY SSF51735 102 274 1.45E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 275 7.8E-96 T 01-11-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 273 36.157 T 01-11-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 116 206 4.1E-12 T 01-11-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MLA2C4_22630 b3880b933863759bc5d2c24073665088 277 Gene3D G3DSA:3.40.50.720 101 241 7.0E-99 T 01-11-2018 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Pfam PF02743 Cache domain 48 264 2.0E-30 T 01-11-2018 IPR033479 Double Cache domain 1 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 SMART SM00283 363 659 8.2E-80 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 SMART SM00304 303 355 6.4E-17 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 SMART SM00304 586 656 63.0 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 430 610 6.2E-52 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Gene3D G3DSA:3.30.450.20 64 274 8.5E-40 T 01-11-2018 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Gene3D G3DSA:1.10.287.950 358 659 1.5E-70 T 01-11-2018 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 SUPERFAMILY SSF103190 94 191 2.79E-9 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Gene3D G3DSA:3.30.450.20 76 183 8.5E-40 T 01-11-2018 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Gene3D G3DSA:1.10.8.500 302 354 1.8E-12 T 01-11-2018 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 SUPERFAMILY SSF58104 323 659 3.27E-77 T 01-11-2018 MLA2C4_10230 c05e1f4d34e9cba4a6c1c21c34c5a6da 660 Pfam PF00672 HAMP domain 304 351 8.8E-16 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 Gene3D G3DSA:3.40.50.1000 6 185 7.1E-53 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 175 1.1E-14 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 1 214 47.976 T 01-11-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 1.4E-56 T 01-11-2018 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 Gene3D G3DSA:1.10.150.240 18 80 7.1E-53 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 51 179 1.9E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 1.0E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 1.0E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 1.0E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.0E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 SUPERFAMILY SSF56784 1 213 4.14E-59 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_26695 50d8010c730a030ccd7a30d895cdcfb8 216 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 74 181 4.8E-13 T 01-11-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MLA2C4_05480 5fc527d603f92dae6d4ca60ddd9329af 283 Gene3D G3DSA:1.20.1260.120 8 283 1.3E-125 T 01-11-2018 MLA2C4_05480 5fc527d603f92dae6d4ca60ddd9329af 283 SUPERFAMILY SSF158430 148 271 6.67E-39 T 01-11-2018 MLA2C4_05480 5fc527d603f92dae6d4ca60ddd9329af 283 Pfam PF11155 Domain of unknown function (DUF2935) 151 267 6.7E-32 T 01-11-2018 IPR021328 Protein of unknown function DUF2935 MLA2C4_05480 5fc527d603f92dae6d4ca60ddd9329af 283 Pfam PF11155 Domain of unknown function (DUF2935) 22 136 4.8E-32 T 01-11-2018 IPR021328 Protein of unknown function DUF2935 MLA2C4_05480 5fc527d603f92dae6d4ca60ddd9329af 283 SUPERFAMILY SSF158430 15 142 2.35E-39 T 01-11-2018 MLA2C4_12470 2ab66ef3eda3f1bde5521d97bae63e84 213 Pfam PF13238 AAA domain 4 142 8.0E-8 T 01-11-2018 MLA2C4_12470 2ab66ef3eda3f1bde5521d97bae63e84 213 Gene3D G3DSA:3.40.50.300 2 195 1.2E-14 T 01-11-2018 MLA2C4_12470 2ab66ef3eda3f1bde5521d97bae63e84 213 SUPERFAMILY SSF52540 3 157 7.48E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.354 T 01-11-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.4E-29 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.4E-29 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.4E-29 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.4E-29 T 01-11-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 2.9E-190 T 01-11-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 Gene3D G3DSA:3.40.50.620 1 305 1.3E-137 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 Pfam PF09190 DALR domain 353 413 1.6E-14 T 01-11-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 SUPERFAMILY SSF47323 317 464 9.48E-35 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 1.6E-137 T 01-11-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 Gene3D G3DSA:1.20.120.640 306 464 3.2E-34 T 01-11-2018 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 SMART SM00840 353 416 1.3E-14 T 01-11-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MLA2C4_00565 89187d42d1f44a71867631e3378bf885 465 SUPERFAMILY SSF52374 4 314 2.2E-104 T 01-11-2018 MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 119 138 8.8E-5 T 01-11-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 8.8E-5 T 01-11-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 216 234 8.8E-5 T 01-11-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 SUPERFAMILY SSF101801 257 325 2.09E-8 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 PIRSF PIRSF002888 2 328 2.9E-58 T 01-11-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 SUPERFAMILY SSF103039 47 234 3.92E-6 T 01-11-2018 IPR028976 CheC-like superfamily MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 258 325 7.7E-13 T 01-11-2018 IPR001543 Surface presentation of antigen (SpoA) MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 Gene3D G3DSA:3.40.1550.10 46 236 3.5E-36 T 01-11-2018 IPR028976 CheC-like superfamily MLA2C4_08690 3e180641a90c08e39779e11d3dead302 328 Pfam PF02154 Flagellar motor switch protein FliM 40 234 7.8E-24 T 01-11-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MLA2C4_21995 03b80b5b5e0133a9796905faf62aa1a1 352 Gene3D G3DSA:3.40.50.12110 13 125 1.7E-48 T 01-11-2018 MLA2C4_21995 03b80b5b5e0133a9796905faf62aa1a1 352 Gene3D G3DSA:3.80.30.30 126 352 5.9E-93 T 01-11-2018 MLA2C4_21995 03b80b5b5e0133a9796905faf62aa1a1 352 SUPERFAMILY SSF102114 95 244 7.06E-5 T 01-11-2018 MLA2C4_21995 03b80b5b5e0133a9796905faf62aa1a1 352 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 15 352 1.2E-161 T 01-11-2018 IPR023897 Spore photoproduct lyase GO:0003913 MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 Gene3D G3DSA:3.20.20.140 73 370 7.6E-171 T 01-11-2018 MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 TIGRFAM TIGR01224 hutI: imidazolonepropionase 33 409 8.4E-155 T 01-11-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 SUPERFAMILY SSF51338 2 416 2.72E-21 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 Pfam PF01979 Amidohydrolase family 69 411 8.3E-20 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 Gene3D G3DSA:2.30.40.10 7 408 7.6E-171 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 SUPERFAMILY SSF51556 72 370 4.29E-80 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_18965 07357d7c89b61e69b51246fd6caadb35 423 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 410 42.747 T 01-11-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_27920 7389dcf4883cc9eeade18b8d21168fa3 247 Gene3D G3DSA:3.30.70.1030 1 136 2.0E-55 T 01-11-2018 MLA2C4_27920 7389dcf4883cc9eeade18b8d21168fa3 247 Pfam PF06778 Chlorite dismutase 33 235 1.6E-76 T 01-11-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase MLA2C4_27920 7389dcf4883cc9eeade18b8d21168fa3 247 Gene3D G3DSA:3.30.70.1100 137 247 7.9E-48 T 01-11-2018 MLA2C4_27920 7389dcf4883cc9eeade18b8d21168fa3 247 SUPERFAMILY SSF54909 1 246 1.05E-94 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_27920 7389dcf4883cc9eeade18b8d21168fa3 247 Hamap MF_01442 Putative heme-dependent peroxidase . 1 247 57.558 T 01-11-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family MLA2C4_26405 0fcf8ac553e273d966c1347a0916590d 352 SUPERFAMILY SSF56219 42 352 3.93E-30 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_26405 0fcf8ac553e273d966c1347a0916590d 352 Gene3D G3DSA:3.60.10.10 49 352 1.5E-32 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_22825 0059ecdb2714cd522c49eaf84724ccd3 212 Pfam PF08241 Methyltransferase domain 50 143 2.0E-14 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_22825 0059ecdb2714cd522c49eaf84724ccd3 212 Gene3D G3DSA:3.40.50.150 24 212 5.7E-55 T 01-11-2018 MLA2C4_22825 0059ecdb2714cd522c49eaf84724ccd3 212 SUPERFAMILY SSF53335 8 199 3.23E-32 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_22825 0059ecdb2714cd522c49eaf84724ccd3 212 Hamap MF_02100 Uncharacterized methyltransferase . 2 212 45.744 T 01-11-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 01-11-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 605 7.2E-43 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 663 7.2E-43 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 7.2E-43 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 616 634 7.2E-43 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 01-11-2018 IPR004176 Clp, N-terminal MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 69 4.4E-15 T 01-11-2018 IPR004176 Clp, N-terminal MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Gene3D G3DSA:1.10.1780.10 1 150 9.8E-62 T 01-11-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 SMART SM00382 538 678 4.0E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 SMART SM00382 201 345 4.1E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Gene3D G3DSA:1.10.8.60 347 482 2.0E-52 T 01-11-2018 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 318 1.8E-13 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Gene3D G3DSA:1.10.8.60 715 811 4.1E-28 T 01-11-2018 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 793 1.5E-27 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 SMART SM01086 715 804 1.3E-38 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Gene3D G3DSA:3.40.50.300 152 344 3.9E-72 T 01-11-2018 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 SUPERFAMILY SSF52540 162 469 2.01E-77 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 SUPERFAMILY SSF81923 5 150 6.99E-33 T 01-11-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 537 709 2.1E-58 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Gene3D G3DSA:3.40.50.300 491 713 3.2E-91 T 01-11-2018 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 SUPERFAMILY SSF52540 487 804 8.26E-84 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 572 590 - T 01-11-2018 IPR028299 ClpA/B, conserved site 2 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Gene3D G3DSA:4.10.860.10 410 468 2.0E-52 T 01-11-2018 MLA2C4_00525 81598e247d1714ac3ed85e3581b06a6f 811 Pfam PF02151 UvrB/uvrC motif 419 452 3.9E-7 T 01-11-2018 IPR001943 UVR domain GO:0005515 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.2E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 1.2E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 1.2E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 1.2E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 188 9.0E-36 T 01-11-2018 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 Gene3D G3DSA:3.40.50.1000 4 197 8.0E-47 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 Gene3D G3DSA:1.10.150.520 16 92 8.0E-47 T 01-11-2018 MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 SUPERFAMILY SSF56784 1 216 1.09E-41 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_24900 0a3b935c589207bb9a1ce68798bdbf6d 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 186 7.9E-16 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 1.6E-44 T 01-11-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 SUPERFAMILY SSF55120 46 235 7.02E-42 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 SUPERFAMILY SSF55174 1 59 6.48E-12 T 01-11-2018 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 SMART SM00363 1 59 4.3E-7 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 01-11-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 Gene3D G3DSA:3.30.70.580 62 230 9.6E-55 T 01-11-2018 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 Gene3D G3DSA:3.30.70.1560 129 212 9.6E-55 T 01-11-2018 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 Gene3D G3DSA:3.10.290.10 1 58 1.1E-16 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 Pfam PF01479 S4 domain 1 45 3.7E-11 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24475 6432d48b91792bd3080e567ce0b0dc9e 242 Pfam PF00849 RNA pseudouridylate synthase 62 195 3.6E-18 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_10500 1d4ea928e1b123f2e0c47a66a8cd7940 405 SUPERFAMILY SSF103473 14 398 1.7E-27 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_10500 1d4ea928e1b123f2e0c47a66a8cd7940 405 Pfam PF07690 Major Facilitator Superfamily 15 356 3.5E-12 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_10500 1d4ea928e1b123f2e0c47a66a8cd7940 405 Gene3D G3DSA:1.20.1250.20 9 392 1.3E-22 T 01-11-2018 MLA2C4_22000 fe13e4810e118f4e57187b5e3d45a729 105 Gene3D G3DSA:1.10.10.10 1 105 1.0E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22000 fe13e4810e118f4e57187b5e3d45a729 105 SUPERFAMILY SSF46785 3 91 1.39E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22000 fe13e4810e118f4e57187b5e3d45a729 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 4.4E-22 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 9 483 2.9E-178 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 SUPERFAMILY SSF53187 13 482 1.6E-53 T 01-11-2018 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 Gene3D G3DSA:3.40.630.10 2 279 1.1E-54 T 01-11-2018 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 Gene3D G3DSA:3.40.630.10 344 487 2.5E-20 T 01-11-2018 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 452 474 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 136 153 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 160 178 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 102 120 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 430 446 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 207 224 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 365 383 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PRINTS PR00934 X-His dipeptidase (M25) signature 81 100 7.0E-49 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 PIRSF PIRSF016599 2 487 9.6E-190 T 01-11-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 Pfam PF07687 Peptidase dimerisation domain 213 291 7.3E-8 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_13295 8427054453975e1e42de63ec284e6799 489 Pfam PF01546 Peptidase family M20/M25/M40 74 480 6.8E-19 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_25020 8bec7f5f788fd7c89d08f4fd1bbca0fb 192 Gene3D G3DSA:2.40.40.60 61 157 9.4E-43 T 01-11-2018 MLA2C4_25020 8bec7f5f788fd7c89d08f4fd1bbca0fb 192 Pfam PF17294 Uncharacterised lipoprotein family 28 191 8.4E-52 T 01-11-2018 IPR035253 Putative lipoprotein, bacteria MLA2C4_25020 8bec7f5f788fd7c89d08f4fd1bbca0fb 192 Gene3D G3DSA:3.30.70.3060 32 175 9.4E-43 T 01-11-2018 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.5E-23 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 SMART SM00448 2 115 1.7E-24 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.4E-16 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.4E-16 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.4E-16 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 SMART SM00421 146 203 3.6E-29 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 Pfam PF00072 Response regulator receiver domain 4 115 1.2E-23 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 Gene3D G3DSA:3.40.50.12740 2 209 3.3E-75 T 01-11-2018 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 SUPERFAMILY SSF46894 139 208 1.67E-24 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_07600 fa7bd479fdbd39fa4b584f1492ecf670 210 SUPERFAMILY SSF52172 1 133 3.56E-32 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 SUPERFAMILY SSF51905 1 242 1.79E-41 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.1E-8 T 01-11-2018 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.1E-8 T 01-11-2018 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 Gene3D G3DSA:3.50.50.60 1 346 5.6E-96 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 4.5E-13 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.5E-13 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 4.5E-13 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 SUPERFAMILY SSF51905 161 316 1.49E-6 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 191 3.5E-40 T 01-11-2018 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PIRSF PIRSF000332 217 309 0.0016 T 01-11-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MLA2C4_17955 069725f6dbb0dc229fae39bb533c0ded 347 PIRSF PIRSF000332 2 194 3.3E-17 T 01-11-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 MLA2C4_06320 23b0048921548df3028f561c6a35471e 462 SUPERFAMILY SSF101967 148 280 2.48E-11 T 01-11-2018 MLA2C4_06320 23b0048921548df3028f561c6a35471e 462 Gene3D G3DSA:4.10.80.40 362 397 1.8E-47 T 01-11-2018 MLA2C4_06320 23b0048921548df3028f561c6a35471e 462 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 264 453 6.9E-45 T 01-11-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain MLA2C4_06320 23b0048921548df3028f561c6a35471e 462 Gene3D G3DSA:2.40.300.10 307 452 1.8E-47 T 01-11-2018 MLA2C4_06320 23b0048921548df3028f561c6a35471e 462 Gene3D G3DSA:2.150.10.10 130 286 6.4E-7 T 01-11-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MLA2C4_15925 ec378f3487c70afcd249ea3e7d125154 310 SMART SM00382 31 172 0.0099 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15925 ec378f3487c70afcd249ea3e7d125154 310 SUPERFAMILY SSF52540 2 282 3.73E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15925 ec378f3487c70afcd249ea3e7d125154 310 Gene3D G3DSA:3.40.50.300 15 181 1.6E-45 T 01-11-2018 MLA2C4_15925 ec378f3487c70afcd249ea3e7d125154 310 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 34 164 8.2E-61 T 01-11-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MLA2C4_15925 ec378f3487c70afcd249ea3e7d125154 310 Gene3D G3DSA:1.10.8.300 195 302 3.7E-30 T 01-11-2018 MLA2C4_15925 ec378f3487c70afcd249ea3e7d125154 310 PIRSF PIRSF002849 1 307 1.5E-126 T 01-11-2018 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.7E-21 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 01-11-2018 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 Gene3D G3DSA:1.10.260.40 3 59 1.5E-23 T 01-11-2018 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 Gene3D G3DSA:3.40.50.2300 156 282 2.2E-81 T 01-11-2018 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 SMART SM00354 1 71 9.9E-36 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 SUPERFAMILY SSF47413 2 59 8.04E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 Pfam PF13377 Periplasmic binding protein-like domain 166 322 2.0E-35 T 01-11-2018 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 SUPERFAMILY SSF53822 60 323 4.52E-81 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 Gene3D G3DSA:3.40.50.2300 62 302 2.2E-81 T 01-11-2018 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-7 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_03505 e74f710ed4985008e390e7a7fa21000d 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-7 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 01-11-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 SUPERFAMILY SSF53187 5 371 3.52E-65 T 01-11-2018 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 SUPERFAMILY SSF55031 180 285 4.84E-20 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 Gene3D G3DSA:3.30.70.360 177 288 2.8E-142 T 01-11-2018 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 368 4.5E-167 T 01-11-2018 IPR010162 Peptidase M20B, peptidase T-like MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 01-11-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 Pfam PF01546 Peptidase family M20/M25/M40 74 368 3.4E-24 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 Gene3D G3DSA:3.40.630.10 14 363 2.8E-142 T 01-11-2018 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 Pfam PF07687 Peptidase dimerisation domain 182 274 2.5E-15 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 PIRSF PIRSF001123 4 96 0.033 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 PIRSF PIRSF001123 258 372 2.5E-5 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_21690 b07eca18336fd7826be8b585f58ed149 372 PIRSF PIRSF001123 80 210 5.7E-5 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 SUPERFAMILY SSF52821 2 150 5.76E-40 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 Gene3D G3DSA:3.40.250.10 150 277 6.9E-33 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 Pfam PF00581 Rhodanese-like domain 5 125 2.2E-20 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 Pfam PF00581 Rhodanese-like domain 155 265 9.4E-15 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 SMART SM00450 3 129 1.1E-22 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 SMART SM00450 152 270 2.6E-18 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 SUPERFAMILY SSF52821 147 273 1.44E-32 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_08265 068ecce03267f22e38183a5888b5c706 277 Gene3D G3DSA:3.40.250.10 1 145 1.4E-46 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_27545 ddc15459ffdf9e7e15608b2f0d47968b 203 Gene3D G3DSA:2.30.110.10 1 203 6.6E-64 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 MLA2C4_27545 ddc15459ffdf9e7e15608b2f0d47968b 203 SUPERFAMILY SSF50475 3 199 6.38E-45 T 01-11-2018 MLA2C4_27545 ddc15459ffdf9e7e15608b2f0d47968b 203 SMART SM00903 20 176 9.2E-26 T 01-11-2018 IPR002563 Flavin reductase like domain GO:0010181 MLA2C4_27545 ddc15459ffdf9e7e15608b2f0d47968b 203 Pfam PF01613 Flavin reductase like domain 23 175 2.0E-23 T 01-11-2018 IPR002563 Flavin reductase like domain GO:0010181 MLA2C4_17525 752c4ff560a48478f4570481d2af6017 149 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_17525 752c4ff560a48478f4570481d2af6017 149 Gene3D G3DSA:3.90.79.10 1 147 8.8E-37 T 01-11-2018 MLA2C4_17525 752c4ff560a48478f4570481d2af6017 149 Pfam PF00293 NUDIX domain 23 142 1.2E-18 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_17525 752c4ff560a48478f4570481d2af6017 149 SUPERFAMILY SSF55811 1 146 2.3E-32 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_17525 752c4ff560a48478f4570481d2af6017 149 PRINTS PR00502 NUDIX hydrolase family signature 57 72 3.8E-5 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_17525 752c4ff560a48478f4570481d2af6017 149 PRINTS PR00502 NUDIX hydrolase family signature 43 57 3.8E-5 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 Gene3D G3DSA:1.10.579.10 289 475 6.1E-87 T 01-11-2018 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 SUPERFAMILY SSF52425 4 167 1.57E-48 T 01-11-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 PRINTS PR00147 DNA photolyase signature 136 152 4.9E-22 T 01-11-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 PRINTS PR00147 DNA photolyase signature 340 358 4.9E-22 T 01-11-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 PRINTS PR00147 DNA photolyase signature 320 336 4.9E-22 T 01-11-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 PRINTS PR00147 DNA photolyase signature 379 393 4.9E-22 T 01-11-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 SUPERFAMILY SSF48173 186 474 3.27E-114 T 01-11-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 Pfam PF00875 DNA photolyase 6 156 4.8E-42 T 01-11-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 Pfam PF03441 FAD binding domain of DNA photolyase 271 470 1.1E-88 T 01-11-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 MLA2C4_16625 f273960072931e93397d73cd8525096a 476 Gene3D G3DSA:3.40.50.620 6 197 4.0E-77 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_16625 f273960072931e93397d73cd8525096a 476 Gene3D G3DSA:1.25.40.80 127 282 4.0E-77 T 01-11-2018 MLA2C4_17230 7618285e815461dc942f1bb3362b0f5d 398 Gene3D G3DSA:1.20.1250.20 199 396 3.2E-24 T 01-11-2018 MLA2C4_17230 7618285e815461dc942f1bb3362b0f5d 398 Gene3D G3DSA:1.20.1250.20 2 198 1.6E-24 T 01-11-2018 MLA2C4_17230 7618285e815461dc942f1bb3362b0f5d 398 Pfam PF07690 Major Facilitator Superfamily 214 387 9.1E-23 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_17230 7618285e815461dc942f1bb3362b0f5d 398 SUPERFAMILY SSF103473 5 381 1.02E-52 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_14450 8365e5a7a28455e97e2baeec6f48ee26 386 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 218 373 4.2E-16 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_14450 8365e5a7a28455e97e2baeec6f48ee26 386 Gene3D G3DSA:3.30.300.210 234 378 2.9E-9 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_14450 8365e5a7a28455e97e2baeec6f48ee26 386 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 377 4.1E-90 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PIRSF PIRSF000126 2 258 2.0E-58 T 01-11-2018 MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 Pfam PF00106 short chain dehydrogenase 8 195 9.0E-62 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 SUPERFAMILY SSF51735 2 254 7.71E-73 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.1E-14 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.1E-14 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.1E-14 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 Gene3D G3DSA:3.40.50.720 1 263 3.7E-77 T 01-11-2018 MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.0E-30 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.0E-30 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.0E-30 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.0E-30 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21630 6a1d87363a8bff33673c359e853332b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.0E-30 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 66.946 T 01-11-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 PIRSF PIRSF001399 1 146 3.4E-63 T 01-11-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 142 9.5E-66 T 01-11-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 Pfam PF01220 Dehydroquinase class II 3 139 3.8E-62 T 01-11-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 Gene3D G3DSA:3.40.50.9100 1 146 1.7E-65 T 01-11-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 SUPERFAMILY SSF52304 3 144 5.1E-59 T 01-11-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 141 1.0E-76 T 01-11-2018 MLA2C4_21965 279ba5b89073608f7e137847c30ea7fe 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 01-11-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 01-11-2018 IPR000808 Mrp, conserved site GO:0005524 MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 113 344 5.3E-83 T 01-11-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 Gene3D G3DSA:3.40.50.300 105 331 2.4E-61 T 01-11-2018 MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 SUPERFAMILY SSF52540 112 346 9.91E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 Hamap MF_02040 Iron-sulfur cluster carrier protein. 105 346 31.891 T 01-11-2018 IPR019591 Mrp/NBP35 ATP-binding protein MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 SUPERFAMILY SSF117916 1 93 1.08E-20 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 Pfam PF01883 Iron-sulfur cluster assembly protein 5 69 8.1E-19 T 01-11-2018 IPR002744 MIP18 family-like MLA2C4_18495 3c6eb8da40ca71652018b1bdea0ce5cd 349 Gene3D G3DSA:3.30.300.130 1 95 3.2E-20 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_22255 c680d7f1ada51b856e6bb8bddae7178c 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22255 c680d7f1ada51b856e6bb8bddae7178c 387 PIRSF PIRSF001434 2 382 7.9E-141 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22255 c680d7f1ada51b856e6bb8bddae7178c 387 SUPERFAMILY SSF53383 16 379 8.86E-108 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22255 c680d7f1ada51b856e6bb8bddae7178c 387 Gene3D G3DSA:3.90.1150.10 247 381 4.3E-43 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22255 c680d7f1ada51b856e6bb8bddae7178c 387 Gene3D G3DSA:3.40.640.10 4 246 2.0E-88 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_22255 c680d7f1ada51b856e6bb8bddae7178c 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 378 4.1E-145 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 583 5.6E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 SUPERFAMILY SSF158472 307 357 3.01E-8 T 01-11-2018 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 SMART SM00304 306 358 4.0E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 SUPERFAMILY SSF55874 434 588 3.93E-39 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 381 444 2.1E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 Gene3D G3DSA:1.10.287.130 371 446 6.9E-20 T 01-11-2018 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 SUPERFAMILY SSF47384 366 444 3.34E-17 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 540 3.5E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 561 579 3.5E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 554 3.5E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 Gene3D G3DSA:3.30.565.10 447 601 4.1E-38 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 Gene3D G3DSA:1.20.1480.50 267 363 5.1E-12 T 01-11-2018 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 SMART SM00388 380 444 1.4E-17 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07710 bc5fdb7d3f001a1175ef4c71ff7747ed 603 SMART SM00387 489 600 1.5E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 SUPERFAMILY SSF64288 61 238 2.51E-51 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 Gene3D G3DSA:1.10.10.10 8 76 6.7E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 SMART SM00866 94 233 4.5E-39 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 SUPERFAMILY SSF46785 1 76 7.61E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 SMART SM00345 14 73 2.7E-21 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.5E-16 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 Pfam PF07702 UTRA domain 96 232 5.5E-38 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 Gene3D G3DSA:3.40.1410.10 77 239 2.9E-50 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 5.9E-10 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_09285 1546f7781e76ba99ccb482b6dd91a4f7 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 5.9E-10 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 Gene3D G3DSA:3.40.190.290 93 299 1.7E-58 T 01-11-2018 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 Pfam PF03466 LysR substrate binding domain 91 294 3.9E-50 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.1E-22 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 SUPERFAMILY SSF46785 5 89 5.28E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 SUPERFAMILY SSF53850 93 298 6.81E-48 T 01-11-2018 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.2E-11 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.2E-11 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.2E-11 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_12505 3d4376cb8991deb9115f7daf7173349f 300 Gene3D G3DSA:1.10.10.10 2 87 3.2E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 Gene3D G3DSA:3.40.50.2300 65 307 1.8E-72 T 01-11-2018 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.5E-18 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 Gene3D G3DSA:3.40.50.2300 159 288 1.8E-72 T 01-11-2018 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 SUPERFAMILY SSF47413 3 59 2.55E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 309 2.8E-31 T 01-11-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 Gene3D G3DSA:1.10.260.40 3 59 8.9E-23 T 01-11-2018 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.2E-5 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.2E-5 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 SUPERFAMILY SSF53822 60 330 2.36E-71 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_05785 fa82683b79856d3885dc3092e6db79a7 338 SMART SM00354 1 71 6.9E-32 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_09130 70efaac6c5bacdf124c9f87469e2d075 1040 Pfam PF13476 AAA domain 7 236 6.3E-14 T 01-11-2018 IPR038729 Rad50/SbcC-type AAA domain MLA2C4_09130 70efaac6c5bacdf124c9f87469e2d075 1040 SUPERFAMILY SSF52540 4 276 4.06E-11 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09130 70efaac6c5bacdf124c9f87469e2d075 1040 SUPERFAMILY SSF52540 5 1013 6.95E-15 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09130 70efaac6c5bacdf124c9f87469e2d075 1040 Gene3D G3DSA:3.40.50.300 797 1024 8.0E-13 T 01-11-2018 MLA2C4_09130 70efaac6c5bacdf124c9f87469e2d075 1040 Gene3D G3DSA:3.40.50.300 3 272 2.9E-16 T 01-11-2018 MLA2C4_23910 6e979a0e11de35dd9cc49f36d5dfde97 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 3.5E-16 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_23910 6e979a0e11de35dd9cc49f36d5dfde97 214 Gene3D G3DSA:1.10.10.10 2 72 1.5E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23910 6e979a0e11de35dd9cc49f36d5dfde97 214 SUPERFAMILY SSF46785 4 86 5.46E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23910 6e979a0e11de35dd9cc49f36d5dfde97 214 SMART SM00345 12 71 5.1E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_23910 6e979a0e11de35dd9cc49f36d5dfde97 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.8E-10 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_23910 6e979a0e11de35dd9cc49f36d5dfde97 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.8E-10 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 9.4E-83 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 3.0E-36 T 01-11-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 Gene3D G3DSA:3.40.50.720 2 165 3.4E-45 T 01-11-2018 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 Gene3D G3DSA:1.10.3730.10 166 273 7.8E-41 T 01-11-2018 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 SUPERFAMILY SSF48179 163 271 9.35E-35 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 25.793 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 4.0E-18 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 PIRSF PIRSF000193 3 271 5.8E-78 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_21640 d94973b8e6460d74f000f833a07e96e5 279 SUPERFAMILY SSF51735 5 162 7.06E-28 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_08070 7ed08ce6a7b3485916e729b0a92d3255 234 Gene3D G3DSA:3.40.50.10320 1 234 2.6E-101 T 01-11-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MLA2C4_08070 7ed08ce6a7b3485916e729b0a92d3255 234 SUPERFAMILY SSF102588 4 226 1.83E-60 T 01-11-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MLA2C4_08070 7ed08ce6a7b3485916e729b0a92d3255 234 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 224 3.1E-100 T 01-11-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 MLA2C4_08070 7ed08ce6a7b3485916e729b0a92d3255 234 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 124 2.4E-24 T 01-11-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MLA2C4_10575 909ee07bd45ede49ef69fa54ceba20ba 295 Pfam PF13673 Acetyltransferase (GNAT) domain 46 112 6.0E-7 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10575 909ee07bd45ede49ef69fa54ceba20ba 295 SUPERFAMILY SSF55729 6 284 1.19E-37 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10575 909ee07bd45ede49ef69fa54ceba20ba 295 Pfam PF00583 Acetyltransferase (GNAT) family 182 275 2.0E-16 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10575 909ee07bd45ede49ef69fa54ceba20ba 295 Gene3D G3DSA:3.40.630.30 1 123 2.1E-9 T 01-11-2018 MLA2C4_10575 909ee07bd45ede49ef69fa54ceba20ba 295 Gene3D G3DSA:3.40.630.30 124 285 4.0E-25 T 01-11-2018 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 38.887 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 1.9E-81 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Gene3D G3DSA:3.40.50.10990 204 374 1.2E-77 T 01-11-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 SUPERFAMILY SSF55821 2 201 2.24E-86 T 01-11-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 55.774 T 01-11-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.097 T 01-11-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Gene3D G3DSA:3.90.870.10 1 203 5.4E-91 T 01-11-2018 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 7.7E-86 T 01-11-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 PIRSF PIRSF001259 1 397 4.0E-190 T 01-11-2018 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 Pfam PF00925 GTP cyclohydrolase II 206 371 3.2E-76 T 01-11-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 208 395 5.0E-81 T 01-11-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MLA2C4_21520 ed0de0de15a00cb9d8acf9f54fccfa67 397 SUPERFAMILY SSF142695 203 374 8.11E-74 T 01-11-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MLA2C4_06965 0f763ae0de64b66598b7ff44570b517f 61 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 1.8E-22 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_06965 0f763ae0de64b66598b7ff44570b517f 61 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_06965 0f763ae0de64b66598b7ff44570b517f 61 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_06965 0f763ae0de64b66598b7ff44570b517f 61 Gene3D G3DSA:1.10.8.910 5 61 7.5E-29 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_08455 f73d65dff2ec0669f8d4d17aee622a50 194 Gene3D G3DSA:3.40.50.880 1 193 2.4E-43 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_08455 f73d65dff2ec0669f8d4d17aee622a50 194 Pfam PF01965 DJ-1/PfpI family 2 166 3.3E-28 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_08455 f73d65dff2ec0669f8d4d17aee622a50 194 SUPERFAMILY SSF52317 1 167 6.11E-35 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 4.1E-72 T 01-11-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 PIRSF PIRSF000149 1 333 1.5E-142 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 5.1E-141 T 01-11-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 01-11-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 SUPERFAMILY SSF51735 3 167 1.28E-67 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 6.5E-43 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 SUPERFAMILY SSF55347 151 313 4.17E-75 T 01-11-2018 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 Gene3D G3DSA:3.30.360.10 150 314 6.4E-161 T 01-11-2018 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 Gene3D G3DSA:3.40.50.720 3 328 6.4E-161 T 01-11-2018 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 SMART SM00846 2 151 3.6E-98 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 5.1E-40 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 5.1E-40 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 5.1E-40 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 5.1E-40 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26585 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 5.1E-40 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Pfam PF08279 HTH domain 6 60 1.8E-15 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Gene3D G3DSA:1.10.10.10 2 63 1.5E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 SUPERFAMILY SSF50037 282 325 1.56E-5 T 01-11-2018 IPR008988 Transcriptional repressor, C-terminal MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Pfam PF02237 Biotin protein ligase C terminal domain 280 324 7.5E-8 T 01-11-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 SUPERFAMILY SSF55681 72 276 3.64E-62 T 01-11-2018 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 326 38.65 T 01-11-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Gene3D G3DSA:2.30.30.100 280 326 3.5E-8 T 01-11-2018 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 SUPERFAMILY SSF46785 3 61 4.99E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Pfam PF03099 Biotin/lipoate A/B protein ligase family 91 214 1.8E-18 T 01-11-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 Gene3D G3DSA:3.30.930.10 68 278 6.4E-70 T 01-11-2018 MLA2C4_08085 b1e3b06b04e653508be58b433ea35be6 326 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 87 324 3.6E-70 T 01-11-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_12280 25d56a98661f792dbc5fbd8b71ac5acd 255 Gene3D G3DSA:3.40.50.300 3 253 2.9E-67 T 01-11-2018 MLA2C4_12280 25d56a98661f792dbc5fbd8b71ac5acd 255 Pfam PF00005 ABC transporter 26 174 1.8E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_12280 25d56a98661f792dbc5fbd8b71ac5acd 255 SMART SM00382 35 223 8.5E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_12280 25d56a98661f792dbc5fbd8b71ac5acd 255 SUPERFAMILY SSF52540 6 234 3.99E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 3.2E-27 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 418 1.9E-183 T 01-11-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 Gene3D G3DSA:3.40.1030.10 77 330 3.8E-155 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 SUPERFAMILY SSF52418 69 329 7.06E-94 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 SUPERFAMILY SSF47648 1 69 9.68E-23 T 01-11-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 Gene3D G3DSA:1.20.970.10 1 67 4.5E-29 T 01-11-2018 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 01-11-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 Gene3D G3DSA:3.90.1170.30 331 419 3.8E-155 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 Pfam PF00591 Glycosyl transferase family, a/b domain 77 306 6.6E-50 T 01-11-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 SUPERFAMILY SSF54680 331 432 3.27E-30 T 01-11-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 SMART SM00941 345 418 1.1E-32 T 01-11-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 3.2E-20 T 01-11-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_21380 5b25a7a5e0cfc9a0ddc3125238154eee 434 PIRSF PIRSF000478 1 432 4.3E-171 T 01-11-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 Gene3D G3DSA:1.10.150.20 46 89 4.6E-5 T 01-11-2018 MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 224 8.4E-83 T 01-11-2018 IPR001405 Uncharacterised protein family UPF0758 MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 Pfam PF04002 RadC-like JAB domain 104 223 3.9E-49 T 01-11-2018 IPR025657 RadC-like JAB domain MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 Gene3D G3DSA:3.40.140.10 101 225 2.2E-49 T 01-11-2018 MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 SUPERFAMILY SSF102712 150 192 5.23E-5 T 01-11-2018 MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 01-11-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MLA2C4_23215 275a1e1cd71c8d85afcd3ca5f4837e0c 225 SUPERFAMILY SSF47781 21 91 2.29E-8 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_03935 e517d0a911ad6fef9b0fccc83271cb88 333 SUPERFAMILY SSF53850 34 260 5.76E-39 T 01-11-2018 MLA2C4_03935 e517d0a911ad6fef9b0fccc83271cb88 333 Gene3D G3DSA:3.40.190.10 117 219 2.7E-95 T 01-11-2018 MLA2C4_03935 e517d0a911ad6fef9b0fccc83271cb88 333 Pfam PF09084 NMT1/THI5 like 44 259 4.5E-78 T 01-11-2018 IPR015168 SsuA/THI5-like MLA2C4_03935 e517d0a911ad6fef9b0fccc83271cb88 333 Gene3D G3DSA:3.40.190.10 37 312 2.7E-95 T 01-11-2018 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Gene3D G3DSA:3.30.980.50 658 768 3.5E-45 T 01-11-2018 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Gene3D G3DSA:1.10.390.20 520 657 1.8E-55 T 01-11-2018 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Pfam PF08453 Peptidase family M9 N-terminal 97 278 2.8E-56 T 01-11-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Gene3D G3DSA:1.10.1740.190 376 519 2.2E-60 T 01-11-2018 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Pfam PF00801 PKD domain 796 847 5.6E-15 T 01-11-2018 IPR000601 PKD domain MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 SMART SM00089 775 857 4.7E-26 T 01-11-2018 IPR022409 PKD/Chitinase domain MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Pfam PF01752 Collagenase 302 628 6.6E-83 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Gene3D G3DSA:2.60.40.10 769 855 3.1E-28 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 SUPERFAMILY SSF89260 863 970 6.15E-29 T 01-11-2018 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 SUPERFAMILY SSF49299 771 856 3.01E-23 T 01-11-2018 IPR035986 PKD domain superfamily MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 449 463 8.0E-32 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 529 544 8.0E-32 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 503 521 8.0E-32 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 163 181 8.0E-32 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 466 482 8.0E-32 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_18295 43e7ce761b63d2192c770a7730ba72f4 971 Gene3D G3DSA:2.60.120.380 856 971 1.4E-24 T 01-11-2018 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 PRINTS PR00046 Major sigma-70 factor signature 85 93 1.5E-11 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 PRINTS PR00046 Major sigma-70 factor signature 220 235 1.5E-11 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 PRINTS PR00046 Major sigma-70 factor signature 61 74 1.5E-11 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 PRINTS PR00046 Major sigma-70 factor signature 203 215 1.5E-11 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 PRINTS PR00046 Major sigma-70 factor signature 235 246 1.5E-11 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 Gene3D G3DSA:1.10.10.10 105 160 2.0E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 Pfam PF04542 Sigma-70 region 2 38 105 4.2E-17 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 Gene3D G3DSA:1.20.120.1810 2 104 2.0E-27 T 01-11-2018 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 Gene3D G3DSA:1.10.10.10 179 252 2.3E-12 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 250 1.5E-117 T 01-11-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 PIRSF PIRSF000770 7 252 2.5E-35 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 249 9.7E-39 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 1.5E-88 T 01-11-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 SUPERFAMILY SSF88659 109 184 5.67E-17 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 Pfam PF04545 Sigma-70, region 4 199 247 2.3E-15 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 SUPERFAMILY SSF88946 6 105 7.33E-34 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 Pfam PF04539 Sigma-70 region 3 115 184 1.5E-14 T 01-11-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MLA2C4_21310 6433b1801eac93669188a595e8e00da0 252 SUPERFAMILY SSF88659 171 250 3.18E-17 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_09865 d8a26f7138bfd6e41cfdd256f91e082a 467 PIRSF PIRSF006446 1 467 2.3E-179 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MLA2C4_09865 d8a26f7138bfd6e41cfdd256f91e082a 467 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 441 3.2E-170 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 01-11-2018 IPR014762 DNA mismatch repair, conserved site MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 SUPERFAMILY SSF54211 189 326 7.21E-38 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 SUPERFAMILY SSF118116 457 645 1.7E-54 T 01-11-2018 IPR037198 MutL, C-terminal domain superfamily MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 643 27.425 T 01-11-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 SUPERFAMILY SSF55874 3 212 6.16E-52 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 3.4E-99 T 01-11-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Gene3D G3DSA:2.30.42.20 462 645 2.7E-63 T 01-11-2018 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Gene3D G3DSA:3.30.230.10 214 325 1.0E-33 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Pfam PF08676 MutL C terminal dimerisation domain 461 603 5.2E-46 T 01-11-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Gene3D G3DSA:3.30.565.10 1 212 1.1E-63 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 4.0E-37 T 01-11-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 SMART SM00853 461 603 3.8E-52 T 01-11-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 SMART SM01340 208 326 1.8E-56 T 01-11-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 120 4.3E-12 T 01-11-2018 MLA2C4_19705 eacb3be239c95b549f7e99130d0ad67c 647 Gene3D G3DSA:3.30.1370.100 503 596 2.7E-63 T 01-11-2018 MLA2C4_06205 f6ea2b85988348ab16687b45d14499e2 126 Pfam PF13038 Domain of unknown function (DUF3899) 35 122 1.9E-21 T 01-11-2018 IPR025007 Domain of unknown function DUF3899 MLA2C4_02125 27e7c0c5c437f5b2a9bb44f53e9e85fe 210 Gene3D G3DSA:3.50.30.50 1 209 2.4E-65 T 01-11-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_02125 27e7c0c5c437f5b2a9bb44f53e9e85fe 210 SUPERFAMILY SSF102198 2 208 1.7E-59 T 01-11-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_02125 27e7c0c5c437f5b2a9bb44f53e9e85fe 210 Pfam PF04199 Putative cyclase 4 151 7.1E-27 T 01-11-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_05655 1ba9f9f6bb6f7eb6fe0d3ed3913504dc 158 SUPERFAMILY SSF103473 25 87 7.46E-5 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_05655 1ba9f9f6bb6f7eb6fe0d3ed3913504dc 158 Pfam PF03703 Bacterial PH domain 72 146 8.8E-14 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 Gene3D G3DSA:3.40.630.40 208 404 2.4E-60 T 01-11-2018 MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 SUPERFAMILY SSF53187 211 401 7.85E-54 T 01-11-2018 MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 Pfam PF00395 S-layer homology domain 90 130 4.8E-5 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 Pfam PF00395 S-layer homology domain 151 192 0.0052 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 Pfam PF00395 S-layer homology domain 28 71 1.7E-12 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 212 396 1.8E-49 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_09230 94cf38571ad21a2e1f2fabc9f79c4587 413 SMART SM00646 277 396 3.3E-41 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 01-11-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 Pfam PF00742 Homoserine dehydrogenase 138 316 7.1E-65 T 01-11-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 Gene3D G3DSA:3.40.50.720 5 338 1.1E-148 T 01-11-2018 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 SUPERFAMILY SSF55347 138 303 1.96E-53 T 01-11-2018 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 SUPERFAMILY SSF55021 349 415 3.88E-8 T 01-11-2018 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 Gene3D G3DSA:3.30.70.260 345 414 1.1E-148 T 01-11-2018 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 Gene3D G3DSA:3.30.360.10 137 344 1.1E-148 T 01-11-2018 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 2.1E-21 T 01-11-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 PIRSF PIRSF000098 2 427 3.6E-174 T 01-11-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_10010 5fb78d0de2936726138ee8c33268db4f 431 SUPERFAMILY SSF51735 1 159 3.38E-36 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_27980 54801d323e8baa87f3b53a58aedde418 305 Gene3D G3DSA:3.40.50.300 1 239 4.5E-63 T 01-11-2018 MLA2C4_27980 54801d323e8baa87f3b53a58aedde418 305 Pfam PF00005 ABC transporter 21 161 2.8E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_27980 54801d323e8baa87f3b53a58aedde418 305 SMART SM00382 29 218 2.4E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_27980 54801d323e8baa87f3b53a58aedde418 305 SUPERFAMILY SSF52540 3 225 3.86E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27980 54801d323e8baa87f3b53a58aedde418 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_22810 601df4a050afb495b5f66c36d701be83 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 376 3.7E-158 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22810 601df4a050afb495b5f66c36d701be83 377 PIRSF PIRSF001434 1 377 7.5E-149 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22810 601df4a050afb495b5f66c36d701be83 377 Gene3D G3DSA:3.40.640.10 1 245 4.6E-93 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_22810 601df4a050afb495b5f66c36d701be83 377 SUPERFAMILY SSF53383 16 376 6.25E-119 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22810 601df4a050afb495b5f66c36d701be83 377 Gene3D G3DSA:3.90.1150.10 246 377 6.9E-53 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22810 601df4a050afb495b5f66c36d701be83 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_06860 7f17ae998cd5bbe088c878b701082ba2 215 Pfam PF01569 PAP2 superfamily 92 202 2.9E-18 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_06860 7f17ae998cd5bbe088c878b701082ba2 215 Gene3D G3DSA:1.20.144.10 119 215 8.6E-23 T 01-11-2018 MLA2C4_06860 7f17ae998cd5bbe088c878b701082ba2 215 Gene3D G3DSA:1.20.144.10 3 118 5.9E-10 T 01-11-2018 MLA2C4_06860 7f17ae998cd5bbe088c878b701082ba2 215 SMART SM00014 87 199 2.3E-20 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_06860 7f17ae998cd5bbe088c878b701082ba2 215 SUPERFAMILY SSF48317 7 204 2.62E-34 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_24530 63df355a5ac53136e0a5e676f6d1cffe 159 SMART SM01058 1 111 4.3E-34 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_24530 63df355a5ac53136e0a5e676f6d1cffe 159 Gene3D G3DSA:1.20.58.1290 63 159 7.0E-29 T 01-11-2018 MLA2C4_24530 63df355a5ac53136e0a5e676f6d1cffe 159 Gene3D G3DSA:2.30.30.840 1 62 3.8E-25 T 01-11-2018 MLA2C4_24530 63df355a5ac53136e0a5e676f6d1cffe 159 Pfam PF02559 CarD-like/TRCF domain 2 110 1.1E-19 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_24530 63df355a5ac53136e0a5e676f6d1cffe 159 SUPERFAMILY SSF141259 2 65 3.14E-13 T 01-11-2018 IPR036101 CarD-like/TRCF domain superfamily MLA2C4_20530 79be61e1703a7610736780411b70b647 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 4.7E-52 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 4.7E-52 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 4.7E-52 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 4.7E-52 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 4.7E-52 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 Pfam PF01467 Cytidylyltransferase-like 9 134 2.9E-20 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.308 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 4.9E-62 T 01-11-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 Gene3D G3DSA:3.40.50.620 1 161 1.5E-59 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_20530 79be61e1703a7610736780411b70b647 163 SUPERFAMILY SSF52374 4 157 3.38E-44 T 01-11-2018 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 64 7.8E-18 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MLA2C4_20530 79be61e1703a7610736780411b70b647 163 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 4.0E-5 T 01-11-2018 MLA2C4_25300 a0e077382615c791b29896969c008912 240 Gene3D G3DSA:3.40.50.1820 13 239 1.3E-45 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_25300 a0e077382615c791b29896969c008912 240 Pfam PF01764 Lipase (class 3) 66 196 5.5E-30 T 01-11-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 MLA2C4_25300 a0e077382615c791b29896969c008912 240 SUPERFAMILY SSF53474 6 219 2.12E-36 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_04830 1bd2f295aa0744d5995610f7c526ee8f 262 SUPERFAMILY SSF52096 6 261 3.32E-63 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_04830 1bd2f295aa0744d5995610f7c526ee8f 262 Gene3D G3DSA:1.10.12.10 205 262 5.5E-19 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MLA2C4_04830 1bd2f295aa0744d5995610f7c526ee8f 262 Gene3D G3DSA:3.90.226.10 1 200 6.8E-51 T 01-11-2018 MLA2C4_04830 1bd2f295aa0744d5995610f7c526ee8f 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 9.6E-50 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 SUPERFAMILY SSF46785 3 83 2.31E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 Gene3D G3DSA:1.10.10.10 1 87 3.4E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 SMART SM00418 9 87 3.0E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 Pfam PF12840 Helix-turn-helix domain 9 67 1.7E-8 T 01-11-2018 MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 2.1E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 2.1E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_17830 9b57c16b51673baa7d809ba7c1f2dd26 87 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.1E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 SUPERFAMILY SSF103473 7 386 8.76E-57 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 Gene3D G3DSA:1.20.1720.10 9 388 2.4E-89 T 01-11-2018 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 Pfam PF07690 Major Facilitator Superfamily 20 350 1.6E-40 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 385 1.5E-68 T 01-11-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 1.3E-9 T 01-11-2018 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 1.3E-9 T 01-11-2018 MLA2C4_18000 ee9ef8b77db3ba255537ceb990dc1637 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 1.3E-9 T 01-11-2018 MLA2C4_07225 be6bab99069d3413ef7e9bd943a3bca8 163 SUPERFAMILY SSF69118 35 158 7.31E-22 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_07225 be6bab99069d3413ef7e9bd943a3bca8 163 Gene3D G3DSA:1.20.1290.10 94 159 4.5E-5 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_07225 be6bab99069d3413ef7e9bd943a3bca8 163 Gene3D G3DSA:1.20.1290.10 33 93 7.4E-7 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SUPERFAMILY SSF54980 400 478 6.83E-26 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SUPERFAMILY SSF54211 477 597 8.85E-44 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SMART SM00889 478 596 9.6E-74 T 01-11-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.2E-36 T 01-11-2018 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 114.194 T 01-11-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 3.9E-44 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SUPERFAMILY SSF50447 263 402 8.58E-37 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Gene3D G3DSA:3.40.50.300 1 291 7.4E-113 T 01-11-2018 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SUPERFAMILY SSF54980 598 688 1.39E-31 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Pfam PF00679 Elongation factor G C-terminus 598 684 1.8E-32 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SUPERFAMILY SSF52540 6 280 3.06E-112 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Pfam PF03764 Elongation factor G, domain IV 477 595 5.2E-48 T 01-11-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 2.6E-16 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Gene3D G3DSA:2.40.30.10 292 403 1.4E-46 T 01-11-2018 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Gene3D G3DSA:3.30.70.870 404 481 1.1E-33 T 01-11-2018 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Gene3D G3DSA:3.30.230.10 482 685 8.5E-96 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Gene3D G3DSA:3.30.70.240 602 672 8.5E-96 T 01-11-2018 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 SMART SM00838 598 685 4.3E-59 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 01-11-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 5.6E-71 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.7E-17 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.7E-17 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.7E-17 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.7E-17 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00655 9f265be67f63e5016dbbfaa64c013eb7 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.7E-17 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_01130 bf299a9e8ad9a630e3f529a6d0434e41 546 Gene3D G3DSA:3.10.105.10 295 517 8.6E-173 T 01-11-2018 MLA2C4_01130 bf299a9e8ad9a630e3f529a6d0434e41 546 Gene3D G3DSA:3.40.190.10 55 530 8.6E-173 T 01-11-2018 MLA2C4_01130 bf299a9e8ad9a630e3f529a6d0434e41 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 463 2.1E-74 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_01130 bf299a9e8ad9a630e3f529a6d0434e41 546 PIRSF PIRSF002741 2 546 1.6E-104 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_01130 bf299a9e8ad9a630e3f529a6d0434e41 546 SUPERFAMILY SSF53850 36 531 3.8E-120 T 01-11-2018 MLA2C4_01130 bf299a9e8ad9a630e3f529a6d0434e41 546 Gene3D G3DSA:3.90.76.10 74 195 8.6E-173 T 01-11-2018 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 SUPERFAMILY SSF57770 137 170 3.79E-8 T 01-11-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 SUPERFAMILY SSF47323 385 540 1.2E-37 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 Gene3D G3DSA:3.40.50.620 3 375 2.4E-148 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 287 302 2.7E-19 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 2.7E-19 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 85 96 2.7E-19 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 2.7E-19 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 380 391 2.7E-19 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 2.7E-19 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 Pfam PF08264 Anticodon-binding domain of tRNA 416 513 3.9E-8 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 Gene3D G3DSA:1.10.730.10 376 539 1.6E-38 T 01-11-2018 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 528 6.7E-159 T 01-11-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 Pfam PF09334 tRNA synthetases class I (M) 4 393 4.4E-139 T 01-11-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 SUPERFAMILY SSF52374 4 380 5.09E-94 T 01-11-2018 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 538 38.701 T 01-11-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 Gene3D G3DSA:2.20.28.20 137 170 2.4E-148 T 01-11-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_26225 e093cbf091e034bbb1c12b457b0f606c 544 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_12770 5f82cb807863d2fdc1b1febb67e4b7c3 182 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 176 14.158 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_12770 5f82cb807863d2fdc1b1febb67e4b7c3 182 Pfam PF02660 Glycerol-3-phosphate acyltransferase 13 178 2.3E-38 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_12770 5f82cb807863d2fdc1b1febb67e4b7c3 182 SMART SM01207 11 176 6.2E-48 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_28230 4b41faff112f3bfbb22c60df72157158 272 Gene3D G3DSA:3.20.20.70 18 270 3.6E-16 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_28230 4b41faff112f3bfbb22c60df72157158 272 SUPERFAMILY SSF51445 39 243 3.28E-20 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_28230 4b41faff112f3bfbb22c60df72157158 272 Pfam PF03537 Glycoside-hydrolase family GH114 51 218 5.3E-14 T 01-11-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 35 398 8.7E-100 T 01-11-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 409 175.788 T 01-11-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 Pfam PF01636 Phosphotransferase enzyme family 34 271 2.2E-12 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 SUPERFAMILY SSF56112 7 402 1.02E-83 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 Gene3D G3DSA:3.30.200.20 1 117 1.2E-35 T 01-11-2018 MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 Gene3D G3DSA:3.90.1200.10 119 405 2.1E-100 T 01-11-2018 MLA2C4_02035 541e4368412d420b1afad4a8a30bbfd6 409 PIRSF PIRSF031134 2 405 2.1E-161 T 01-11-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 Pfam PF00302 Chloramphenicol acetyltransferase 3 205 5.5E-88 T 01-11-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 ProSitePatterns PS00100 Chloramphenicol acetyltransferase active site. 186 196 - T 01-11-2018 IPR018372 Chloramphenicol acetyltransferase, active site GO:0008811 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 SUPERFAMILY SSF52777 1 211 2.0E-76 T 01-11-2018 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 9 204 1.0E-105 T 01-11-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 PIRSF PIRSF000440 1 214 6.2E-89 T 01-11-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 Gene3D G3DSA:3.30.559.10 2 208 2.8E-70 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_12400 df89112ffeabc8e78c80523b1aef9d06 216 SMART SM01059 1 205 4.7E-117 T 01-11-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 PRINTS PR00050 Cold shock protein signature 23 32 1.4E-19 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 PRINTS PR00050 Cold shock protein signature 3 18 1.4E-19 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 PRINTS PR00050 Cold shock protein signature 38 56 1.4E-19 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 SUPERFAMILY SSF50249 1 64 4.21E-25 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 6.0E-33 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 PIRSF PIRSF002599 1 65 1.5E-24 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 Gene3D G3DSA:2.40.50.140 1 65 1.8E-30 T 01-11-2018 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 SMART SM00357 2 65 3.3E-32 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_26855 68b15a896d5c4931d85a92d39b14f078 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 01-11-2018 IPR019844 Cold-shock conserved site MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 SMART SM00283 388 663 3.7E-64 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 SUPERFAMILY SSF58104 327 663 1.57E-70 T 01-11-2018 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 SMART SM00304 541 594 77.0 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 SMART SM00304 307 359 1.2E-14 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 460 596 6.0E-36 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Gene3D G3DSA:1.20.1480.50 277 365 2.7E-17 T 01-11-2018 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Gene3D G3DSA:3.30.450.20 188 275 1.6E-26 T 01-11-2018 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Pfam PF02743 Cache domain 40 268 2.0E-27 T 01-11-2018 IPR033479 Double Cache domain 1 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Gene3D G3DSA:3.30.450.20 94 187 1.6E-26 T 01-11-2018 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Gene3D G3DSA:1.10.287.950 366 663 5.9E-65 T 01-11-2018 MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 SUPERFAMILY SSF103190 99 198 1.39E-7 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_26070 f6dc6b1e08a9d32dfa969c699259c88d 666 Pfam PF00672 HAMP domain 307 354 2.7E-11 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 Gene3D G3DSA:3.40.50.1820 6 268 1.0E-68 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 SUPERFAMILY SSF53474 3 267 1.61E-57 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 19 267 2.4E-90 T 01-11-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 PRINTS PR00412 Epoxide hydrolase signature 104 117 2.9E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 PRINTS PR00412 Epoxide hydrolase signature 243 265 2.9E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 PRINTS PR00412 Epoxide hydrolase signature 25 43 2.9E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 Pfam PF00561 alpha/beta hydrolase fold 20 254 5.5E-23 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 267 37.242 T 01-11-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 5.0E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 5.0E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25265 10bb5acceff8e3184e71601b412074f7 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 5.0E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 SUPERFAMILY SSF51735 1 158 1.69E-35 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 Gene3D G3DSA:3.30.360.10 136 343 2.9E-147 T 01-11-2018 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 SUPERFAMILY SSF55347 137 302 1.24E-52 T 01-11-2018 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 Pfam PF01842 ACT domain 351 403 3.9E-8 T 01-11-2018 IPR002912 ACT domain MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 PIRSF PIRSF000098 1 429 6.9E-168 T 01-11-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 SUPERFAMILY SSF55021 348 414 4.58E-10 T 01-11-2018 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 Gene3D G3DSA:3.30.70.260 344 415 2.9E-147 T 01-11-2018 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 355 397 0.002 T 01-11-2018 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 01-11-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 Gene3D G3DSA:3.40.50.720 4 336 2.9E-147 T 01-11-2018 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 Pfam PF00742 Homoserine dehydrogenase 137 315 2.8E-65 T 01-11-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_28000 4099bed7804c48c52945af29b5f5d7ec 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.0E-22 T 01-11-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 Gene3D G3DSA:3.10.20.80 1 73 1.7E-34 T 01-11-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 SUPERFAMILY SSF54364 2 73 5.62E-30 T 01-11-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 78 163 2.2E-38 T 01-11-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 SUPERFAMILY SSF55200 77 166 2.75E-33 T 01-11-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 164 1.3E-76 T 01-11-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 ProSitePatterns PS00938 Initiation factor 3 signature. 53 66 - T 01-11-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 165 29.983 T 01-11-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 71 6.0E-34 T 01-11-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_23770 e8795d4602bcf3b5172a213913038cb5 166 Gene3D G3DSA:3.30.110.10 74 166 6.2E-38 T 01-11-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MLA2C4_04400 8a1aea69df480290911fc2fe7c058d3a 288 SUPERFAMILY SSF161098 70 272 4.06E-10 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_04400 8a1aea69df480290911fc2fe7c058d3a 288 Gene3D G3DSA:1.10.3720.10 67 280 1.3E-9 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_04400 8a1aea69df480290911fc2fe7c058d3a 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 284 5.8E-12 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_18040 85c128d282b2ac24d38baae45c3b29de 295 SUPERFAMILY SSF52540 3 222 3.25E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18040 85c128d282b2ac24d38baae45c3b29de 295 Gene3D G3DSA:3.40.50.300 2 257 5.9E-54 T 01-11-2018 MLA2C4_18040 85c128d282b2ac24d38baae45c3b29de 295 Pfam PF00005 ABC transporter 19 157 5.9E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18040 85c128d282b2ac24d38baae45c3b29de 295 SMART SM00382 28 205 1.4E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 Pfam PF07690 Major Facilitator Superfamily 103 494 6.7E-54 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 SUPERFAMILY SSF103473 87 593 3.66E-68 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 126 6.3E-12 T 01-11-2018 MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 193 213 6.3E-12 T 01-11-2018 MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 387 411 6.3E-12 T 01-11-2018 MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 223 247 6.3E-12 T 01-11-2018 MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 100 587 3.2E-137 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_23735 50994bc82adafe52cde2537f541f0576 599 Gene3D G3DSA:1.20.1720.10 99 307 8.3E-44 T 01-11-2018 MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 Gene3D G3DSA:1.20.120.420 1 148 2.4E-50 T 01-11-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 SUPERFAMILY SSF100950 2 342 1.09E-115 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 Pfam PF01008 Initiation factor 2 subunit family 49 335 8.5E-86 T 01-11-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 37.592 T 01-11-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 336 2.9E-121 T 01-11-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 Gene3D G3DSA:3.40.50.10470 149 352 6.1E-66 T 01-11-2018 MLA2C4_21090 b44cdc5406ef8a39647dce3992bc52e4 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 1.8E-140 T 01-11-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_13045 d7928403afb57baed76ae5855f209df3 167 TIGRFAM TIGR02126 phgtail_TP901_1: phage major tail protein, TP901-1 family 10 143 6.5E-42 T 01-11-2018 IPR011855 Phage major tail protein TP901-1 MLA2C4_13045 d7928403afb57baed76ae5855f209df3 167 Pfam PF06199 Phage tail tube protein 12 146 1.7E-28 T 01-11-2018 IPR011855 Phage major tail protein TP901-1 MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.9E-41 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-41 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.9E-41 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.9E-41 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.9E-41 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.9E-41 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 7.1E-66 T 01-11-2018 MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.9E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.9E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 SUPERFAMILY SSF51735 7 253 5.39E-84 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 Gene3D G3DSA:3.40.50.720 1 261 5.8E-88 T 01-11-2018 MLA2C4_24535 aa6c4dee21f99074a300b46b53937b6b 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 Gene3D G3DSA:3.40.1350.30 136 291 2.7E-117 T 01-11-2018 MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 390 421 - T 01-11-2018 IPR030390 RNA methyltransferase TrmA, active site MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 95 458 1.2E-18 T 01-11-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 Gene3D G3DSA:2.40.50.140 2 86 4.0E-24 T 01-11-2018 MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 Pfam PF01938 TRAM domain 10 65 1.2E-12 T 01-11-2018 IPR002792 TRAM domain MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 441 451 - T 01-11-2018 IPR030391 RNA methyltransferase TrmA, conserved site MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 SUPERFAMILY SSF50249 3 66 4.85E-16 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 Gene3D G3DSA:3.40.50.150 88 453 2.7E-117 T 01-11-2018 MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 451 3.3E-176 T 01-11-2018 MLA2C4_02545 7302ccdc01c0b755fa98f4f68ca9e939 459 SUPERFAMILY SSF53335 75 458 9.98E-83 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 SUPERFAMILY SSF46894 130 230 4.76E-32 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 Gene3D G3DSA:1.10.10.10 132 235 4.3E-40 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 SMART SM00448 4 114 1.7E-48 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 Pfam PF00072 Response regulator receiver domain 6 115 9.4E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 SUPERFAMILY SSF52172 1 123 5.69E-45 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 Gene3D G3DSA:3.40.50.2300 2 131 5.6E-42 T 01-11-2018 MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 9.2E-28 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_28350 9c39ac8ecead29d91cc71f14e8b27a47 235 SMART SM00862 153 229 1.6E-27 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_22975 50a1959f89a1d8223bfacf0d37f7d0a7 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.7E-60 T 01-11-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MLA2C4_22975 50a1959f89a1d8223bfacf0d37f7d0a7 146 SUPERFAMILY SSF69500 1 144 3.66E-60 T 01-11-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MLA2C4_22975 50a1959f89a1d8223bfacf0d37f7d0a7 146 Gene3D G3DSA:3.50.80.10 1 146 5.3E-60 T 01-11-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MLA2C4_22975 50a1959f89a1d8223bfacf0d37f7d0a7 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.432 T 01-11-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MLA2C4_22975 50a1959f89a1d8223bfacf0d37f7d0a7 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 1.3E-58 T 01-11-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MLA2C4_20940 d424413357870d7647ae4b7dc7ea19dc 144 Pfam PF14040 Deoxyribonuclease NucA/NucB 46 129 1.6E-10 T 01-11-2018 IPR029476 Deoxyribonuclease NucA/NucB MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 SUPERFAMILY SSF52096 29 281 6.63E-84 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 Pfam PF01039 Carboxyl transferase domain 62 242 4.7E-21 T 01-11-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 1.6E-38 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 1.6E-38 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 1.6E-38 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 1.6E-38 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 1.6E-38 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 39.067 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 Gene3D G3DSA:3.90.226.10 28 282 6.5E-89 T 01-11-2018 MLA2C4_23905 8240e7ed2280e15243f3f16b37bbcbcc 289 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 16 280 4.3E-130 T 01-11-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_20920 f145d534a107e6c0bc99419341a73b07 185 SUPERFAMILY SSF46785 3 170 2.27E-28 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_20920 f145d534a107e6c0bc99419341a73b07 185 Pfam PF03551 Transcriptional regulator PadR-like family 7 82 5.7E-9 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_20920 f145d534a107e6c0bc99419341a73b07 185 Gene3D G3DSA:1.10.10.10 1 89 3.2E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10315 7928cf50761ab3a3638a56829344975f 345 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 320 3.9E-87 T 01-11-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MLA2C4_10315 7928cf50761ab3a3638a56829344975f 345 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 66.863 T 01-11-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 MLA2C4_10315 7928cf50761ab3a3638a56829344975f 345 SUPERFAMILY SSF51395 3 334 1.86E-111 T 01-11-2018 MLA2C4_10315 7928cf50761ab3a3638a56829344975f 345 Gene3D G3DSA:3.20.20.70 2 338 6.7E-121 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_22625 5f3413c4e1de6e75afd4c035cfbd5cdc 97 SMART SM01103 2 85 1.6E-42 T 01-11-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MLA2C4_22625 5f3413c4e1de6e75afd4c035cfbd5cdc 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 97 6.0E-46 T 01-11-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MLA2C4_22625 5f3413c4e1de6e75afd4c035cfbd5cdc 97 SUPERFAMILY SSF75471 1 95 2.35E-31 T 01-11-2018 IPR035920 YhbY-like superfamily MLA2C4_22625 5f3413c4e1de6e75afd4c035cfbd5cdc 97 Gene3D G3DSA:3.30.110.60 1 97 1.2E-36 T 01-11-2018 IPR035920 YhbY-like superfamily MLA2C4_22625 5f3413c4e1de6e75afd4c035cfbd5cdc 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 97 8.3E-41 T 01-11-2018 IPR017924 RNA-binding protein YhbY GO:0003723 MLA2C4_22625 5f3413c4e1de6e75afd4c035cfbd5cdc 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 1.0E-21 T 01-11-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Gene3D G3DSA:3.40.1390.10 3 96 6.5E-27 T 01-11-2018 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Pfam PF01225 Mur ligase family, catalytic domain 22 93 1.0E-13 T 01-11-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Pfam PF08245 Mur ligase middle domain 106 311 5.4E-56 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 SUPERFAMILY SSF63418 1 97 1.12E-25 T 01-11-2018 IPR035911 MurE/MurF, N-terminal MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 SUPERFAMILY SSF53623 97 331 6.02E-76 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Gene3D G3DSA:3.90.190.20 337 491 3.8E-61 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Gene3D G3DSA:3.40.1190.10 97 336 1.0E-89 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 1.5E-22 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 SUPERFAMILY SSF53244 332 486 4.71E-50 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 483 36.673 T 01-11-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MLA2C4_20455 80e7a8246c5d4b999203cdfb962c5309 491 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 483 2.0E-171 T 01-11-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MLA2C4_16120 cd331a2fbd1637a98a0ecf637f2173be 253 Pfam PF08241 Methyltransferase domain 56 142 9.2E-8 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_16120 cd331a2fbd1637a98a0ecf637f2173be 253 Gene3D G3DSA:3.40.50.150 35 191 1.1E-13 T 01-11-2018 MLA2C4_16120 cd331a2fbd1637a98a0ecf637f2173be 253 SUPERFAMILY SSF53335 47 190 9.79E-17 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_19835 8e835866637202468d567a518073dab8 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.2E-9 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19835 8e835866637202468d567a518073dab8 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.2E-9 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19835 8e835866637202468d567a518073dab8 241 SUPERFAMILY SSF64288 63 239 3.14E-38 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_19835 8e835866637202468d567a518073dab8 241 Gene3D G3DSA:1.10.10.10 3 74 1.8E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19835 8e835866637202468d567a518073dab8 241 SMART SM00345 14 73 4.3E-21 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19835 8e835866637202468d567a518073dab8 241 SUPERFAMILY SSF46785 5 84 6.0E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19835 8e835866637202468d567a518073dab8 241 Gene3D G3DSA:3.40.1410.10 77 239 9.3E-31 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_19835 8e835866637202468d567a518073dab8 241 Pfam PF07702 UTRA domain 96 232 1.4E-31 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_19835 8e835866637202468d567a518073dab8 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 9.2E-22 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19835 8e835866637202468d567a518073dab8 241 SMART SM00866 95 233 3.2E-24 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 Pfam PF07702 UTRA domain 90 227 5.5E-37 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.3E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.3E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 SMART SM00345 8 67 4.3E-14 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 SMART SM00866 89 228 3.9E-32 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 Gene3D G3DSA:1.10.10.10 1 67 2.4E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 4 235 2.5E-103 T 01-11-2018 IPR012770 Trehalose operon transcriptional repressor MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 SUPERFAMILY SSF64288 55 235 1.18E-43 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 Gene3D G3DSA:3.40.1410.10 74 231 3.3E-33 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 SUPERFAMILY SSF46785 2 71 2.41E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03315 06c48e8613d2779420dbc26c4acda732 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 5.2E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_00995 f40ae892a34e1b8623e4ca0797890dc2 303 Pfam PF13800 Sigma factor regulator N-terminal 6 95 4.6E-24 T 01-11-2018 IPR029101 Sigma factor regulator, N-terminal MLA2C4_00995 f40ae892a34e1b8623e4ca0797890dc2 303 Pfam PF13791 Sigma factor regulator C-terminal 163 291 4.8E-17 T 01-11-2018 IPR025672 Sigma factor regulator C-terminal domain MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 SMART SM00841 129 184 3.2E-34 T 01-11-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 SUPERFAMILY SSF50249 65 129 6.43E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 SUPERFAMILY SSF50249 128 185 3.22E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 PIRSF PIRSF005901 1 185 1.1E-72 T 01-11-2018 IPR020599 Translation elongation factor P/YeiP MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Gene3D G3DSA:2.40.50.140 128 185 2.6E-27 T 01-11-2018 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 01-11-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.353 T 01-11-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 4.1E-28 T 01-11-2018 IPR013185 Translation elongation factor, KOW-like MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Gene3D G3DSA:2.40.50.140 64 127 3.0E-27 T 01-11-2018 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 SUPERFAMILY SSF50104 1 63 3.55E-22 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 SMART SM01185 67 121 8.5E-26 T 01-11-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.5E-22 T 01-11-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 4.4E-83 T 01-11-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.9E-26 T 01-11-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MLA2C4_21955 c824ca10e4429df2e0bd30448bed0a96 185 Gene3D G3DSA:2.30.30.30 1 62 1.1E-31 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 MLA2C4_06820 ef5319e2a90b440736415248e7d313ba 107 Pfam PF08671 Anti-repressor SinI 72 99 3.4E-15 T 01-11-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 MLA2C4_06820 ef5319e2a90b440736415248e7d313ba 107 SUPERFAMILY SSF47413 2 67 5.35E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_06820 ef5319e2a90b440736415248e7d313ba 107 Pfam PF01381 Helix-turn-helix 6 60 1.4E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_06820 ef5319e2a90b440736415248e7d313ba 107 SMART SM00530 5 61 2.1E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_06820 ef5319e2a90b440736415248e7d313ba 107 SUPERFAMILY SSF47406 72 105 3.14E-14 T 01-11-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 MLA2C4_06820 ef5319e2a90b440736415248e7d313ba 107 Gene3D G3DSA:1.10.260.40 1 107 7.4E-33 T 01-11-2018 MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 Gene3D G3DSA:3.90.660.20 41 408 1.0E-146 T 01-11-2018 MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 SUPERFAMILY SSF51905 3 459 3.45E-53 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 Gene3D G3DSA:3.50.50.60 6 450 1.0E-146 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 Pfam PF01593 Flavin containing amine oxidoreductase 12 459 3.9E-71 T 01-11-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 Gene3D G3DSA:1.10.3110.10 107 200 1.0E-146 T 01-11-2018 MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 463 1.2E-128 T 01-11-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MLA2C4_05715 e6ad6372faada739c8a887b8539155f4 473 SUPERFAMILY SSF54373 301 409 8.34E-35 T 01-11-2018 MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 Gene3D G3DSA:2.40.40.10 156 302 2.2E-8 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 SMART SM00287 82 144 1.7E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 SMART SM00287 23 79 3.4E-5 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 Gene3D G3DSA:2.30.30.40 19 82 5.5E-14 T 01-11-2018 MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 Gene3D G3DSA:2.30.30.40 83 142 3.5E-15 T 01-11-2018 MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 SUPERFAMILY SSF50685 248 299 1.67E-10 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 Pfam PF06725 3D domain 249 309 4.6E-20 T 01-11-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 Pfam PF08239 Bacterial SH3 domain 91 138 3.1E-10 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_19405 a549e226f1a0c835add04e62102c3929 310 Pfam PF08239 Bacterial SH3 domain 32 80 1.6E-9 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 Gene3D G3DSA:3.30.700.10 7 99 1.4E-8 T 01-11-2018 MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 1.5E-5 T 01-11-2018 IPR012902 Prokaryotic N-terminal methylation site MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 SUPERFAMILY SSF54523 7 90 1.1E-13 T 01-11-2018 MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 01-11-2018 IPR012902 Prokaryotic N-terminal methylation site MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 8.2E-11 T 01-11-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 8.2E-11 T 01-11-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 PIRSF PIRSF029928 1 97 4.8E-34 T 01-11-2018 IPR016940 ComG operon protein C GO:0030420 MLA2C4_22180 47df87da065524f7786759dc4a3c5d60 99 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 1.2E-6 T 01-11-2018 IPR012902 Prokaryotic N-terminal methylation site MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.2E-33 T 01-11-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 SUPERFAMILY SSF47336 2 77 1.09E-21 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.9E-15 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.155 T 01-11-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 Gene3D G3DSA:1.10.1200.10 1 77 2.0E-27 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 01-11-2018 IPR006162 Phosphopantetheine attachment site MLA2C4_20120 1ae876407cd1c445ecb71bd2b1272e28 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 77 2.0E-13 T 01-11-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MLA2C4_00625 3e8d4602e86684ccfb2d89b167bfcf91 199 Pfam PF05175 Methyltransferase small domain 28 195 5.2E-53 T 01-11-2018 IPR007848 Methyltransferase small domain GO:0008168 MLA2C4_00625 3e8d4602e86684ccfb2d89b167bfcf91 199 SUPERFAMILY SSF53335 12 197 8.67E-41 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_00625 3e8d4602e86684ccfb2d89b167bfcf91 199 Gene3D G3DSA:3.40.50.150 6 199 1.8E-49 T 01-11-2018 MLA2C4_05380 45165bc319a5d204ef4589d5739067d9 405 Pfam PF07730 Histidine kinase 199 265 5.2E-13 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_05380 45165bc319a5d204ef4589d5739067d9 405 SUPERFAMILY SSF55874 271 395 1.69E-15 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05380 45165bc319a5d204ef4589d5739067d9 405 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 396 1.3E-6 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05380 45165bc319a5d204ef4589d5739067d9 405 Gene3D G3DSA:3.30.565.10 264 402 2.0E-25 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05380 45165bc319a5d204ef4589d5739067d9 405 SMART SM00387 301 398 0.0015 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 Pfam PF02195 ParB-like nuclease domain 28 115 1.3E-28 T 01-11-2018 IPR003115 ParB/Sulfiredoxin MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 23 201 5.4E-62 T 01-11-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 Gene3D G3DSA:3.90.1530.30 40 102 1.2E-28 T 01-11-2018 MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 SUPERFAMILY SSF109709 108 219 1.41E-36 T 01-11-2018 MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 SMART SM00470 27 116 3.4E-36 T 01-11-2018 IPR003115 ParB/Sulfiredoxin MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 Pfam PF01381 Helix-turn-helix 133 166 2.4E-6 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 SUPERFAMILY SSF110849 27 118 1.8E-29 T 01-11-2018 IPR036086 ParB/Sulfiredoxin superfamily MLA2C4_28435 56b2c3ef438f117eaa08d9868a8612c1 285 Gene3D G3DSA:1.10.10.2830 103 232 1.1E-37 T 01-11-2018 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 Pfam PF13492 GAF domain 203 318 5.2E-10 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 Gene3D G3DSA:3.30.450.40 7 178 8.8E-22 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 SUPERFAMILY SSF55781 28 179 8.72E-19 T 01-11-2018 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 SMART SM00065 197 326 0.0091 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 SMART SM00065 25 176 0.0024 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 SUPERFAMILY SSF55781 185 344 3.93E-12 T 01-11-2018 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 Pfam PF07730 Histidine kinase 333 400 7.4E-21 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 Pfam PF13185 GAF domain 29 166 1.0E-12 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 Gene3D G3DSA:3.30.450.40 184 331 4.1E-15 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 Gene3D G3DSA:3.30.565.10 404 522 4.7E-23 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_28040 015497feb3c63f889c6750e7226c8a4d 523 SUPERFAMILY SSF55874 403 522 1.72E-11 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_04585 c902ce878fd425e690e65d805309ef77 179 Gene3D G3DSA:3.10.450.50 21 179 9.6E-53 T 01-11-2018 MLA2C4_04585 c902ce878fd425e690e65d805309ef77 179 SUPERFAMILY SSF54427 57 176 8.78E-29 T 01-11-2018 IPR032710 NTF2-like domain superfamily MLA2C4_04585 c902ce878fd425e690e65d805309ef77 179 Pfam PF07366 SnoaL-like polyketide cyclase 59 173 2.3E-30 T 01-11-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 SUPERFAMILY SSF55008 6 73 6.81E-12 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Pfam PF00403 Heavy-metal-associated domain 87 135 6.5E-10 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Pfam PF00403 Heavy-metal-associated domain 10 71 3.2E-11 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 ProSitePatterns PS01047 Heavy-metal-associated domain. 90 119 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 487 493 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Gene3D G3DSA:3.40.1110.10 496 607 2.7E-83 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Gene3D G3DSA:3.30.70.100 7 85 1.1E-10 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Gene3D G3DSA:3.30.70.100 86 172 8.9E-12 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 SUPERFAMILY SSF81653 286 383 8.11E-25 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Gene3D G3DSA:2.70.150.20 270 387 8.5E-32 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 485 499 4.1E-21 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 4.1E-21 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 698 4.1E-21 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 703 715 4.1E-21 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 633 4.1E-21 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 SUPERFAMILY SSF81665 234 773 1.57E-12 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 257 758 3.7E-78 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 234 782 8.4E-177 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Pfam PF00122 E1-E2 ATPase 284 464 1.2E-50 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 SUPERFAMILY SSF55008 85 159 9.29E-12 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 693 1.6E-35 T 01-11-2018 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 Gene3D G3DSA:3.40.50.1000 466 732 2.7E-83 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00941 Cadmium-transporting ATPase signature 349 365 2.3E-16 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00941 Cadmium-transporting ATPase signature 99 120 2.3E-16 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00941 Cadmium-transporting ATPase signature 196 213 2.3E-16 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00941 Cadmium-transporting ATPase signature 268 288 2.3E-16 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00941 Cadmium-transporting ATPase signature 368 382 2.3E-16 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 PRINTS PR00941 Cadmium-transporting ATPase signature 88 97 2.3E-16 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 SUPERFAMILY SSF56784 483 780 6.79E-62 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_03155 194e1eff87d30d820a9b51d475c2d692 788 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 234 784 7.7E-164 T 01-11-2018 MLA2C4_14175 1b60354f25f14d2c19890b75c26039b1 190 Pfam PF01965 DJ-1/PfpI family 1 164 4.5E-20 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_14175 1b60354f25f14d2c19890b75c26039b1 190 SUPERFAMILY SSF52317 1 178 1.03E-30 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_14175 1b60354f25f14d2c19890b75c26039b1 190 Gene3D G3DSA:3.40.50.880 1 187 2.3E-41 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:1.10.150.700 1092 1181 3.1E-36 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:1.10.150.700 1203 1282 4.3E-14 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:2.40.50.140 216 317 4.5E-35 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Pfam PF14579 Helix-hairpin-helix motif 1348 1424 2.0E-8 T 01-11-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 823 1232 2.9E-94 T 01-11-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:1.10.100.20 991 1038 6.6E-58 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:1.10.150.870 1284 1419 1.5E-51 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Pfam PF14480 DNA polymerase III polC-type N-terminus I 10 80 4.5E-19 T 01-11-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 205 3.8E-23 T 01-11-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 SUPERFAMILY SSF53098 417 873 6.32E-105 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 227 1433 0.0 T 01-11-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:3.20.20.140 552 798 1.5E-57 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:3.30.420.10 407 551 9.1E-45 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 SMART SM00481 332 399 2.1E-26 T 01-11-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 SUPERFAMILY SSF50249 236 317 1.14E-9 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 410 631 1.0E-64 T 01-11-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 SMART SM00479 417 583 2.8E-55 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Pfam PF02811 PHP domain 333 691 9.3E-52 T 01-11-2018 IPR004013 PHP domain GO:0003824 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1433 450.453 T 01-11-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 SUPERFAMILY SSF160975 1372 1412 6.28E-6 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Gene3D G3DSA:3.30.1900.20 969 1091 6.6E-58 T 01-11-2018 MLA2C4_19960 051b0dc7867ad4c55cbab6d4ae76af2b 1433 Pfam PF00929 Exonuclease 419 573 7.7E-42 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 42.009 T 01-11-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 Pfam PF12706 Beta-lactamase superfamily domain 203 271 6.9E-10 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 Gene3D G3DSA:3.60.15.10 1 305 1.9E-106 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 SMART SM00849 18 270 8.8E-4 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 303 5.2E-118 T 01-11-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 SUPERFAMILY SSF56281 2 305 2.83E-85 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21655 f083366dfa82d98a1a484d0ef282ebba 307 Pfam PF00753 Metallo-beta-lactamase superfamily 26 94 2.0E-9 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_13455 ee65ed5f1e5daba5fd79292442d1bcf0 322 Pfam PF08349 Protein of unknown function (DUF1722) 191 307 3.4E-41 T 01-11-2018 IPR013560 Domain of unknown function DUF1722 MLA2C4_13455 ee65ed5f1e5daba5fd79292442d1bcf0 322 Pfam PF04463 Protein of unknown function (DUF523) 9 149 2.3E-35 T 01-11-2018 IPR007553 Domain of unknown function DUF523 MLA2C4_13455 ee65ed5f1e5daba5fd79292442d1bcf0 322 PIRSF PIRSF037004 1 316 2.1E-124 T 01-11-2018 IPR017087 Uncharacterised conserved protein UCP037004 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 180 197 - T 01-11-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 5 354 7.7E-174 T 01-11-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 Gene3D G3DSA:3.30.420.40 5 356 1.8E-161 T 01-11-2018 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 Hamap MF_00542 Probable butyrate kinase [buk]. 1 367 174.006 T 01-11-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 Gene3D G3DSA:3.30.420.40 138 333 1.8E-161 T 01-11-2018 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 Pfam PF00871 Acetokinase family 6 350 1.6E-75 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 SUPERFAMILY SSF53067 118 348 8.64E-57 T 01-11-2018 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 SUPERFAMILY SSF53067 5 173 1.51E-74 T 01-11-2018 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 PIRSF PIRSF036458 2 357 4.3E-180 T 01-11-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 PRINTS PR00471 Acetate kinase family signature 298 314 2.0E-17 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 PRINTS PR00471 Acetate kinase family signature 180 201 2.0E-17 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 PRINTS PR00471 Acetate kinase family signature 6 17 2.0E-17 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 PRINTS PR00471 Acetate kinase family signature 275 288 2.0E-17 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_21775 2de3a43abc6917827a5e215146a968a9 367 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 01-11-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_15075 95e3f696d7b9c113be68c863695abe2d 333 Gene3D G3DSA:2.30.30.40 23 139 1.4E-46 T 01-11-2018 MLA2C4_15075 95e3f696d7b9c113be68c863695abe2d 333 Gene3D G3DSA:2.30.30.40 140 207 3.5E-36 T 01-11-2018 MLA2C4_15075 95e3f696d7b9c113be68c863695abe2d 333 SUPERFAMILY SSF54001 207 332 4.17E-40 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_15075 95e3f696d7b9c113be68c863695abe2d 333 Pfam PF00877 NlpC/P60 family 223 330 1.3E-26 T 01-11-2018 IPR000064 Endopeptidase, NLPC/P60 domain MLA2C4_15075 95e3f696d7b9c113be68c863695abe2d 333 Gene3D G3DSA:3.90.1720.10 208 333 1.0E-40 T 01-11-2018 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 Gene3D G3DSA:3.30.1360.60 1 77 8.1E-30 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 SUPERFAMILY SSF55604 6 78 1.7E-22 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 Gene3D G3DSA:2.70.70.10 471 626 3.9E-53 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 483 607 4.2E-48 T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 627 1.3E-226 T 01-11-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 SUPERFAMILY SSF51261 475 627 7.85E-53 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 Pfam PF02378 Phosphotransferase system, EIIC 103 397 1.2E-32 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 Pfam PF00367 phosphotransferase system, EIIB 8 41 1.5E-15 T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 484 604 5.6E-43 T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_05105 58783d5f0a981bdefe42514b8aab576a 630 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 546 558 - T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 2 163 1.4E-57 T 01-11-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 59 129 1.4E-5 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 27 137 5.5E-24 T 01-11-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 SUPERFAMILY SSF56784 14 147 1.21E-25 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 Pfam PF13242 HAD-hyrolase-like 90 135 6.9E-12 T 01-11-2018 MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 Pfam PF08282 haloacid dehalogenase-like hydrolase 29 84 7.9E-5 T 01-11-2018 MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 Gene3D G3DSA:3.40.50.1000 15 159 1.9E-24 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_22640 08148e046f2de4fec66563adedf79a89 170 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 35 135 8.2E-8 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 SUPERFAMILY SSF48334 21 284 3.14E-23 T 01-11-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 405 421 - T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 Gene3D G3DSA:1.10.1420.10 22 277 7.1E-7 T 01-11-2018 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 Gene3D G3DSA:3.40.50.300 288 552 6.8E-67 T 01-11-2018 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 Gene3D G3DSA:1.10.1420.10 113 222 7.1E-7 T 01-11-2018 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 SUPERFAMILY SSF52540 289 511 1.27E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 Pfam PF00488 MutS domain V 326 507 9.0E-32 T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 SMART SM00534 323 508 3.4E-53 T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 SMART SM00533 9 311 9.5E-21 T 01-11-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 PIRSF PIRSF005814 564 633 0.53 T 01-11-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MLA2C4_18125 1243148d5cfaffcb3d365490aa01acd4 633 PIRSF PIRSF005814 1 582 2.5E-208 T 01-11-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 88 6.3E-22 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 296 1.8E-103 T 01-11-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 SUPERFAMILY SSF56349 2 288 2.83E-63 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 Gene3D G3DSA:1.10.443.10 110 290 4.3E-70 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 Pfam PF00589 Phage integrase family 110 282 5.8E-56 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 Gene3D G3DSA:1.10.150.130 2 98 3.7E-23 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 62.799 T 01-11-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 59.077 T 01-11-2018 IPR023009 Tyrosine recombinase XerC/XerD MLA2C4_21400 2738fff6723a6040c3cb2cefc9127b36 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 7.4E-126 T 01-11-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 Pfam PF02634 FdhD/NarQ family 26 261 6.6E-78 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 Gene3D G3DSA:3.10.20.10 28 110 1.3E-14 T 01-11-2018 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 SUPERFAMILY SSF53927 6 261 2.5E-75 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 261 1.5E-70 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 Gene3D G3DSA:3.40.140.10 117 267 2.1E-46 T 01-11-2018 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 PIRSF PIRSF015626 2 265 2.5E-75 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_03120 c39bcb48e16e666ff650f44c3522651f 268 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 262 31.041 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 SMART SM00487 261 460 4.4E-25 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 SUPERFAMILY SSF52540 193 445 4.91E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 SMART SM00490 563 660 8.9E-8 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 Gene3D G3DSA:1.10.8.630 3 115 9.9E-27 T 01-11-2018 MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 SUPERFAMILY SSF52540 529 705 1.75E-35 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 TIGRFAM TIGR00595 priA: primosomal protein N' 289 797 8.9E-219 T 01-11-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 Pfam PF04851 Type III restriction enzyme, res subunit 264 428 4.5E-16 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 Pfam PF00271 Helicase conserved C-terminal domain 563 659 1.7E-7 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 800 24.976 T 01-11-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MLA2C4_20215 4792341e105738bd6335836732dd2fd2 801 Gene3D G3DSA:3.40.50.300 252 447 1.0E-76 T 01-11-2018 MLA2C4_09970 82c5637c7ae18d8c68b40d59f0824a35 305 SMART SM00382 31 235 3.9E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09970 82c5637c7ae18d8c68b40d59f0824a35 305 Gene3D G3DSA:3.40.50.300 2 239 1.6E-58 T 01-11-2018 MLA2C4_09970 82c5637c7ae18d8c68b40d59f0824a35 305 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_09970 82c5637c7ae18d8c68b40d59f0824a35 305 SUPERFAMILY SSF52540 4 231 5.75E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09970 82c5637c7ae18d8c68b40d59f0824a35 305 Pfam PF00005 ABC transporter 23 162 2.3E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 2 1306 0.0 T 01-11-2018 IPR023839 Firmicutes EssC, C-terminal MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 SUPERFAMILY SSF52540 444 705 2.68E-33 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 SUPERFAMILY SSF52540 798 1009 7.69E-18 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 Gene3D G3DSA:3.40.50.300 428 727 5.1E-83 T 01-11-2018 MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 SMART SM00382 822 1271 0.81 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 SMART SM00382 485 666 0.4 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 Pfam PF01580 FtsK/SpoIIIE family 479 669 4.5E-29 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 Pfam PF01580 FtsK/SpoIIIE family 800 994 4.2E-24 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 Pfam PF01580 FtsK/SpoIIIE family 1097 1242 2.2E-13 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 Gene3D G3DSA:3.40.50.300 1075 1312 3.5E-25 T 01-11-2018 MLA2C4_11040 f43975ed4af1489a9088952f9ebf771f 1335 Gene3D G3DSA:3.40.50.300 771 1066 5.7E-60 T 01-11-2018 MLA2C4_14600 fdf3963afaf4afaf1206c4bb03b2926a 306 Pfam PF00144 Beta-lactamase 37 282 3.4E-24 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_14600 fdf3963afaf4afaf1206c4bb03b2926a 306 Gene3D G3DSA:3.40.710.10 2 289 4.2E-63 T 01-11-2018 MLA2C4_14600 fdf3963afaf4afaf1206c4bb03b2926a 306 SUPERFAMILY SSF56601 5 298 1.63E-66 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 3.6E-22 T 01-11-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 Gene3D G3DSA:3.40.1280.10 74 243 2.2E-54 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 Gene3D G3DSA:3.30.1330.30 1 73 9.3E-12 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 SUPERFAMILY SSF55315 3 76 4.0E-18 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 242 6.0E-83 T 01-11-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 Pfam PF00588 SpoU rRNA Methylase family 96 236 1.8E-38 T 01-11-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 SMART SM00967 5 79 5.1E-22 T 01-11-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MLA2C4_00575 022de1c406627e9ca2109487beecc993 247 SUPERFAMILY SSF75217 67 243 6.54E-49 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 SUPERFAMILY SSF55874 243 407 3.8E-42 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 Gene3D G3DSA:3.30.565.10 257 410 5.3E-41 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 SUPERFAMILY SSF47384 178 254 2.35E-14 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 Pfam PF00512 His Kinase A (phospho-acceptor) domain 187 252 1.1E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 SMART SM00387 298 409 3.1E-35 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 SMART SM00388 186 253 1.3E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 408 1.9E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 Gene3D G3DSA:1.10.287.130 174 255 6.0E-18 T 01-11-2018 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 7.5E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 406 7.5E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 349 7.5E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03045 6ba9e49f30e49979a5481c82695655dc 411 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 363 7.5E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_18435 694381dcee87a2a23c1aac69184d3a7c 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 302 6.2E-64 T 01-11-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MLA2C4_18435 694381dcee87a2a23c1aac69184d3a7c 310 Gene3D G3DSA:3.90.245.10 1 310 9.1E-76 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_18435 694381dcee87a2a23c1aac69184d3a7c 310 SUPERFAMILY SSF53590 1 309 9.03E-80 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_21410 3fbeaf2c19136b65ce092dbf15583217 151 Gene3D G3DSA:3.30.1490.190 93 150 8.5E-18 T 01-11-2018 MLA2C4_21410 3fbeaf2c19136b65ce092dbf15583217 151 SUPERFAMILY SSF46785 6 142 6.12E-38 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21410 3fbeaf2c19136b65ce092dbf15583217 151 Gene3D G3DSA:1.10.10.10 1 88 5.8E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21410 3fbeaf2c19136b65ce092dbf15583217 151 Pfam PF01475 Ferric uptake regulator family 16 136 1.5E-38 T 01-11-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MLA2C4_05220 f9d0bfb1733a7132bb7dd2beaac0a257 36 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 11 33 2.7E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_05220 f9d0bfb1733a7132bb7dd2beaac0a257 36 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 3.6E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 Pfam PF00072 Response regulator receiver domain 6 115 7.9E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 1.6E-26 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 SUPERFAMILY SSF52172 1 189 1.99E-44 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 Gene3D G3DSA:1.10.10.10 131 232 9.5E-36 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 Gene3D G3DSA:3.40.50.2300 1 130 1.1E-40 T 01-11-2018 MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 SMART SM00448 4 114 3.3E-46 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_25245 827bf8a399db52f17c9762b8c06b3324 232 SMART SM00862 154 230 4.7E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_25585 d76104645a5ae4d2fa84890b33d5c4e7 247 Gene3D G3DSA:3.90.640.20 152 247 5.9E-26 T 01-11-2018 IPR037126 PdaC/RsiV-like superfamily MLA2C4_25585 d76104645a5ae4d2fa84890b33d5c4e7 247 Pfam PF13739 Domain of unknown function (DUF4163) 40 135 7.4E-23 T 01-11-2018 IPR025303 Deacetylase PdaC MLA2C4_25585 d76104645a5ae4d2fa84890b33d5c4e7 247 Pfam PF11738 Protein of unknown function (DUF3298) 154 228 2.2E-18 T 01-11-2018 IPR021729 Domain of unknown function DUF3298 MLA2C4_25585 d76104645a5ae4d2fa84890b33d5c4e7 247 Gene3D G3DSA:3.30.565.40 31 150 4.6E-27 T 01-11-2018 MLA2C4_07725 75dfb167641444a949f9f188b9578930 860 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 298 6.0E-19 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MLA2C4_07725 75dfb167641444a949f9f188b9578930 860 SUPERFAMILY SSF55729 657 834 3.6E-12 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_07725 75dfb167641444a949f9f188b9578930 860 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 547 837 5.0E-93 T 01-11-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal MLA2C4_07725 75dfb167641444a949f9f188b9578930 860 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 201 303 5.3E-16 T 01-11-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 SUPERFAMILY SSF54106 30 74 1.57E-10 T 01-11-2018 MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 SMART SM00257 31 74 1.0E-10 T 01-11-2018 IPR018392 LysM domain MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 SMART SM00257 98 141 9.3E-12 T 01-11-2018 IPR018392 LysM domain MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Pfam PF07486 Cell Wall Hydrolase 162 263 3.4E-23 T 01-11-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 SUPERFAMILY SSF54106 97 140 2.62E-11 T 01-11-2018 MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Pfam PF01476 LysM domain 99 140 2.7E-11 T 01-11-2018 IPR018392 LysM domain MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Pfam PF01476 LysM domain 32 74 8.4E-12 T 01-11-2018 IPR018392 LysM domain MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Gene3D G3DSA:2.40.10.420 233 265 1.8E-13 T 01-11-2018 MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Gene3D G3DSA:1.10.10.2520 149 229 1.2E-26 T 01-11-2018 MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Gene3D G3DSA:3.10.350.10 20 86 2.1E-16 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_19660 912993086aa9363947ddab9f853ea26f 265 Gene3D G3DSA:3.10.350.10 87 148 7.5E-15 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_10005 cf86bc1342aff1aa24a74dfec0f1eaee 212 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 16 212 2.2E-80 T 01-11-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent MLA2C4_10005 cf86bc1342aff1aa24a74dfec0f1eaee 212 SUPERFAMILY SSF50475 27 180 3.93E-19 T 01-11-2018 MLA2C4_10005 cf86bc1342aff1aa24a74dfec0f1eaee 212 Gene3D G3DSA:2.30.110.10 37 163 1.5E-23 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 MLA2C4_10005 cf86bc1342aff1aa24a74dfec0f1eaee 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 40 131 1.5E-12 T 01-11-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 357 6.9E-138 T 01-11-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 SUPERFAMILY SSF52402 7 244 2.05E-58 T 01-11-2018 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 Pfam PF03054 tRNA methyl transferase 9 357 2.3E-145 T 01-11-2018 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 358 40.384 T 01-11-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 Gene3D G3DSA:2.30.30.280 214 277 1.2E-22 T 01-11-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 Gene3D G3DSA:2.40.30.10 279 370 6.9E-30 T 01-11-2018 MLA2C4_22930 12e1572f4fbf982a4c572b0fc5a4bf7a 371 Gene3D G3DSA:3.40.50.620 1 213 4.7E-98 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_19745 81c04c342a3ba675e6d0197d487c04f1 86 Gene3D G3DSA:3.30.110.20 1 86 7.2E-35 T 01-11-2018 IPR036882 Alba-like domain superfamily GO:0003676 MLA2C4_19745 81c04c342a3ba675e6d0197d487c04f1 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 1.7E-38 T 01-11-2018 IPR007347 Sporulation stage V, protein S MLA2C4_19745 81c04c342a3ba675e6d0197d487c04f1 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 1.0E-40 T 01-11-2018 IPR007347 Sporulation stage V, protein S MLA2C4_15225 a975de60575299e18fb8f1e72d0faab0 256 Pfam PF12746 GNAT acetyltransferase 15 251 1.8E-84 T 01-11-2018 IPR027365 GNAT acetyltransferase YdfB-like MLA2C4_15225 a975de60575299e18fb8f1e72d0faab0 256 Gene3D G3DSA:3.40.630.110 6 115 7.5E-25 T 01-11-2018 MLA2C4_15225 a975de60575299e18fb8f1e72d0faab0 256 SUPERFAMILY SSF55729 98 254 1.22E-13 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15225 a975de60575299e18fb8f1e72d0faab0 256 Gene3D G3DSA:3.40.630.30 116 242 2.8E-46 T 01-11-2018 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 Pfam PF00561 alpha/beta hydrolase fold 24 132 1.0E-23 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 Gene3D G3DSA:3.40.50.1820 1 268 1.9E-64 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00412 Epoxide hydrolase signature 29 47 4.9E-9 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00412 Epoxide hydrolase signature 49 64 4.9E-9 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00412 Epoxide hydrolase signature 211 227 4.9E-9 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00412 Epoxide hydrolase signature 244 266 4.9E-9 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 SUPERFAMILY SSF53474 2 268 5.23E-59 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 6.8E-10 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 6.8E-10 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24855 322541f4c2452911a15f1bae605a403f 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 6.8E-10 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 Gene3D G3DSA:1.20.140.10 235 379 6.0E-59 T 01-11-2018 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 SUPERFAMILY SSF47203 227 378 9.67E-62 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 SUPERFAMILY SSF56645 2 242 1.24E-97 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 6.0E-29 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.2E-43 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 Gene3D G3DSA:2.40.110.10 121 234 2.2E-48 T 01-11-2018 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 Gene3D G3DSA:1.10.540.10 1 120 1.7E-47 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 9.6E-54 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 PIRSF PIRSF016578 4 376 1.8E-20 T 01-11-2018 MLA2C4_27655 2efb58118129663da144e0f5f5665085 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 Gene3D G3DSA:3.40.50.720 97 238 1.2E-23 T 01-11-2018 MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 Pfam PF02254 TrkA-N domain 118 238 9.0E-13 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 SUPERFAMILY SSF51735 115 251 2.36E-16 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 SUPERFAMILY SSF81324 14 136 1.96E-24 T 01-11-2018 MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 Pfam PF07885 Ion channel 21 97 8.9E-14 T 01-11-2018 IPR013099 Potassium channel domain MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 SUPERFAMILY SSF116726 282 329 3.4E-5 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_25485 bf0a039f3fce64ebaa7351ffbd7496da 331 Gene3D G3DSA:1.10.287.70 2 96 1.7E-20 T 01-11-2018 MLA2C4_02650 d5e1108d7d1e1497975195e589d3cabd 243 Pfam PF13353 4Fe-4S single cluster domain 15 146 7.0E-23 T 01-11-2018 MLA2C4_02650 d5e1108d7d1e1497975195e589d3cabd 243 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 01-11-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 MLA2C4_02650 d5e1108d7d1e1497975195e589d3cabd 243 SUPERFAMILY SSF102114 21 222 2.35E-28 T 01-11-2018 MLA2C4_02650 d5e1108d7d1e1497975195e589d3cabd 243 Gene3D G3DSA:3.20.20.70 1 243 7.5E-99 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_02650 d5e1108d7d1e1497975195e589d3cabd 243 Pfam PF04055 Radical SAM superfamily 23 184 7.7E-31 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_02650 d5e1108d7d1e1497975195e589d3cabd 243 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 241 2.0E-103 T 01-11-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 SUPERFAMILY SSF48179 205 298 3.06E-28 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 Gene3D G3DSA:3.40.50.720 2 202 1.3E-57 T 01-11-2018 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 406 9.8E-137 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 SMART SM00984 317 411 6.2E-30 T 01-11-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 410 8.1E-21 T 01-11-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 296 3.4E-26 T 01-11-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 PIRSF PIRSF000124 5 413 3.1E-67 T 01-11-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 PIRSF PIRSF500136 1 414 8.9E-152 T 01-11-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 Gene3D G3DSA:3.40.50.720 205 414 1.2E-55 T 01-11-2018 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 SUPERFAMILY SSF51735 6 195 6.73E-40 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 189 3.0E-40 T 01-11-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MLA2C4_02630 8d857a483e41601d9c824871bf3fb2cd 414 SUPERFAMILY SSF52413 312 410 9.02E-21 T 01-11-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 SMART SM00347 32 128 7.4E-23 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 Pfam PF01047 MarR family 37 93 1.5E-14 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 Gene3D G3DSA:1.10.10.10 3 139 8.9E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 4.3E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 4.3E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 4.3E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 4.3E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21360 94856de0f35e3bc01425835125b18553 139 SUPERFAMILY SSF46785 8 138 2.1E-28 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 PIRSF PIRSF000429 1 390 3.3E-125 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 01-11-2018 IPR020613 Thiolase, conserved site GO:0016747 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 Pfam PF00108 Thiolase, N-terminal domain 5 259 4.2E-69 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 SUPERFAMILY SSF53901 268 389 3.19E-44 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 01-11-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 Gene3D G3DSA:3.40.47.10 127 386 2.0E-144 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 SUPERFAMILY SSF53901 1 262 6.01E-68 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 7.8E-135 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 Pfam PF02803 Thiolase, C-terminal domain 268 388 9.7E-50 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 Gene3D G3DSA:3.40.47.10 6 273 2.0E-144 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_26035 607fe4b4a839178e198dc01d433596a4 390 ProSitePatterns PS00099 Thiolases active site. 371 384 - T 01-11-2018 IPR020610 Thiolase, active site GO:0016747 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 Gene3D G3DSA:3.20.19.10 664 901 4.8E-104 T 01-11-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 Pfam PF00330 Aconitase family (aconitate hydratase) 77 571 1.8E-176 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 SUPERFAMILY SSF53732 4 636 1.96E-227 T 01-11-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 Gene3D G3DSA:3.30.499.10 376 599 1.5E-101 T 01-11-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 Gene3D G3DSA:1.10.1440.20 600 660 1.9E-23 T 01-11-2018 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 Pfam PF00694 Aconitase C-terminal domain 701 828 1.2E-46 T 01-11-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 SUPERFAMILY SSF52016 640 898 8.04E-88 T 01-11-2018 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 01-11-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 Gene3D G3DSA:3.30.499.20 5 375 3.3E-158 T 01-11-2018 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 219 234 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 440 451 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 147 160 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 502 515 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 375 389 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 281 294 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 171 179 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 295 308 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_18805 f0661505969a40b546a17f00e4bca394 907 PRINTS PR00415 Aconitase family signature 205 218 1.3E-39 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 SUPERFAMILY SSF64288 65 239 3.3E-29 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 SMART SM00345 18 77 4.5E-14 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 SUPERFAMILY SSF46785 10 81 2.43E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.4E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.5E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.5E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 Gene3D G3DSA:3.40.1410.10 75 229 1.3E-25 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 Gene3D G3DSA:1.10.10.10 10 74 1.3E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 Pfam PF07702 UTRA domain 99 231 1.1E-21 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_25205 237b875a58bfd0a3493999dc34ad5b85 241 SMART SM00866 98 234 5.2E-16 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_14165 184e21a2a529743eb8b9f347a12c5f53 168 Pfam PF11385 Protein of unknown function (DUF3189) 3 150 8.8E-50 T 01-11-2018 IPR021525 Protein of unknown function DUF3189 MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 Pfam PF01546 Peptidase family M20/M25/M40 72 382 4.8E-32 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 Gene3D G3DSA:3.30.70.360 181 295 1.0E-137 T 01-11-2018 MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 Gene3D G3DSA:3.40.630.10 14 372 1.0E-137 T 01-11-2018 MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 SUPERFAMILY SSF53187 12 388 4.09E-80 T 01-11-2018 MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 Pfam PF07687 Peptidase dimerisation domain 186 279 4.2E-11 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 PIRSF PIRSF005962 6 389 2.2E-129 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 SUPERFAMILY SSF55031 181 298 2.62E-29 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_07285 c0ed0e8eb46f7edfe5d59a4288905457 389 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 374 1.1E-110 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 33.529 T 01-11-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 01-11-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 Gene3D G3DSA:3.65.10.10 23 231 4.3E-158 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 PIRSF PIRSF000505 1 429 2.4E-120 T 01-11-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 Gene3D G3DSA:3.65.10.10 13 424 4.3E-158 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 424 3.1E-129 T 01-11-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 01-11-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 428 7.0E-134 T 01-11-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MLA2C4_15550 a94de7a63865ed2e2bc50a497f649cd0 429 SUPERFAMILY SSF55205 11 427 1.54E-138 T 01-11-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 Pfam PF04055 Radical SAM superfamily 119 282 2.9E-17 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 SUPERFAMILY SSF102114 102 320 5.76E-14 T 01-11-2018 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 Gene3D G3DSA:3.20.20.70 80 343 7.0E-99 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 14 362 1.2E-158 T 01-11-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 358 71.913 T 01-11-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 Gene3D G3DSA:1.10.150.530 1 77 3.6E-21 T 01-11-2018 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 Pfam PF13394 4Fe-4S single cluster domain 124 221 1.4E-5 T 01-11-2018 MLA2C4_20195 a0afdf2651d78bf9657ba5def80dec37 362 PIRSF PIRSF006004 8 362 1.4E-134 T 01-11-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 MLA2C4_12955 03613b5c257da41b03dd2789321fa0b8 401 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 271 283 - T 01-11-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 MLA2C4_12955 03613b5c257da41b03dd2789321fa0b8 401 Pfam PF00069 Protein kinase domain 160 303 2.5E-29 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MLA2C4_12955 03613b5c257da41b03dd2789321fa0b8 401 SUPERFAMILY SSF56112 160 310 1.35E-34 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_12955 03613b5c257da41b03dd2789321fa0b8 401 Gene3D G3DSA:1.10.510.10 153 349 9.5E-37 T 01-11-2018 MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 SUPERFAMILY SSF46785 3 112 5.12E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 Gene3D G3DSA:3.40.190.290 92 288 1.5E-44 T 01-11-2018 MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.8E-7 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.8E-7 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.8E-7 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 7.9E-17 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 Pfam PF03466 LysR substrate binding domain 90 286 2.0E-36 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 Gene3D G3DSA:1.10.10.10 1 83 7.9E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25660 0effa2aa4d7adb3bb4b5591a5777f7c1 289 SUPERFAMILY SSF53850 91 286 1.78E-33 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF05031 Iron Transport-associated domain 43 158 1.9E-29 T 01-11-2018 IPR006635 NEAT domain MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 416 437 9.3 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 460 481 81.0 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 285 306 1.4 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 351 372 78.0 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 394 415 510.0 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 438 459 64.0 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 307 325 39.0 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00365 329 350 230.0 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Gene3D G3DSA:2.60.40.1850 34 162 2.2E-37 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF00395 S-layer homology domain 594 636 4.5E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF00395 S-layer homology domain 654 695 2.5E-9 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF00395 S-layer homology domain 714 757 3.6E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 PRINTS PR00019 Leucine-rich repeat signature 416 429 9.7E-5 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 PRINTS PR00019 Leucine-rich repeat signature 288 301 9.7E-5 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00369 416 437 190.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00369 438 461 12.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00369 329 352 66.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00369 307 328 75.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00369 285 305 25.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SUPERFAMILY SSF52058 216 492 3.74E-49 T 01-11-2018 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SMART SM00725 41 165 3.2E-14 T 01-11-2018 IPR006635 NEAT domain MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SUPERFAMILY SSF81296 497 569 9.33E-10 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 SUPERFAMILY SSF158911 45 161 9.42E-31 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Gene3D G3DSA:3.80.10.10 375 498 3.5E-25 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Gene3D G3DSA:3.80.10.10 176 374 7.3E-44 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF12799 Leucine Rich repeats (2 copies) 332 371 2.1E-7 T 01-11-2018 IPR025875 Leucine rich repeat 4 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF12799 Leucine Rich repeats (2 copies) 417 458 1.1E-7 T 01-11-2018 IPR025875 Leucine rich repeat 4 MLA2C4_07055 b069744b1cb86f4c75ada2db70b81756 766 Pfam PF12799 Leucine Rich repeats (2 copies) 287 327 2.9E-10 T 01-11-2018 IPR025875 Leucine rich repeat 4 MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 SUPERFAMILY SSF46785 5 86 2.45E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 Pfam PF12840 Helix-turn-helix domain 10 68 4.2E-11 T 01-11-2018 MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 7.6E-7 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 7.6E-7 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 7.6E-7 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 Gene3D G3DSA:1.10.10.10 3 90 2.6E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16210 a0a4655909271655f1bf371f8497d449 242 SMART SM00418 9 88 1.6E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_04115 12357b127fc65ed8a67f7c9544c76fb6 186 SUPERFAMILY SSF55469 8 182 9.82E-37 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_04115 12357b127fc65ed8a67f7c9544c76fb6 186 Gene3D G3DSA:3.40.109.10 1 186 2.4E-53 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_04115 12357b127fc65ed8a67f7c9544c76fb6 186 Pfam PF00881 Nitroreductase family 11 164 4.5E-29 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_04115 12357b127fc65ed8a67f7c9544c76fb6 186 PIRSF PIRSF000232 3 186 2.4E-37 T 01-11-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like MLA2C4_04290 e06168f8ffd76dc83e328879cf90444e 119 Pfam PF00581 Rhodanese-like domain 33 118 2.7E-15 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04290 e06168f8ffd76dc83e328879cf90444e 119 Gene3D G3DSA:3.40.250.10 25 119 2.2E-26 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04290 e06168f8ffd76dc83e328879cf90444e 119 SMART SM00450 30 119 2.1E-17 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04290 e06168f8ffd76dc83e328879cf90444e 119 SUPERFAMILY SSF52821 9 118 1.15E-28 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_12485 9e87026b19e7dda00276abe6734cf71b 296 SUPERFAMILY SSF46785 4 117 9.32E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12485 9e87026b19e7dda00276abe6734cf71b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 5.2E-18 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_12485 9e87026b19e7dda00276abe6734cf71b 296 Pfam PF03466 LysR substrate binding domain 95 294 5.0E-34 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_12485 9e87026b19e7dda00276abe6734cf71b 296 Gene3D G3DSA:1.10.10.10 9 96 2.0E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_12485 9e87026b19e7dda00276abe6734cf71b 296 Gene3D G3DSA:3.40.190.290 97 296 4.4E-29 T 01-11-2018 MLA2C4_12485 9e87026b19e7dda00276abe6734cf71b 296 SUPERFAMILY SSF53850 94 294 4.1E-33 T 01-11-2018 MLA2C4_14525 cb57f6b85d78cf7abccefae5504604af 305 SUPERFAMILY SSF103481 37 139 6.8E-14 T 01-11-2018 MLA2C4_14525 cb57f6b85d78cf7abccefae5504604af 305 SUPERFAMILY SSF103481 186 290 4.18E-16 T 01-11-2018 MLA2C4_14525 cb57f6b85d78cf7abccefae5504604af 305 Pfam PF00892 EamA-like transporter family 4 134 8.1E-17 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_14525 cb57f6b85d78cf7abccefae5504604af 305 Pfam PF00892 EamA-like transporter family 149 287 1.9E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 220 8.8E-25 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 Pfam PF00072 Response regulator receiver domain 3 113 4.3E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 Gene3D G3DSA:1.10.10.10 123 224 6.1E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 SUPERFAMILY SSF52172 1 178 4.53E-42 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 SMART SM00862 145 220 1.3E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 Gene3D G3DSA:3.40.50.2300 1 122 5.4E-41 T 01-11-2018 MLA2C4_16915 b3b153b6d103bafbb8cedd3cd042ccd6 224 SMART SM00448 1 112 1.3E-43 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_17580 a085e848a605eb869e9513a6497810b2 239 SUPERFAMILY SSF52317 14 215 4.74E-33 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_17580 a085e848a605eb869e9513a6497810b2 239 Gene3D G3DSA:3.40.50.880 1 236 1.7E-58 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_17580 a085e848a605eb869e9513a6497810b2 239 Pfam PF00117 Glutamine amidotransferase class-I 42 185 1.3E-16 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_04750 ee0929d63c04de4a143399c19587f7de 496 SMART SM00729 171 395 1.8E-45 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_04750 ee0929d63c04de4a143399c19587f7de 496 Pfam PF04055 Radical SAM superfamily 179 351 2.0E-16 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_04750 ee0929d63c04de4a143399c19587f7de 496 Gene3D G3DSA:3.80.30.20 133 486 5.7E-66 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe MLA2C4_04750 ee0929d63c04de4a143399c19587f7de 496 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 90 490 8.2E-148 T 01-11-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ MLA2C4_04750 ee0929d63c04de4a143399c19587f7de 496 SUPERFAMILY SSF102114 164 478 1.12E-69 T 01-11-2018 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 Gene3D G3DSA:1.10.10.10 1 73 1.8E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 SMART SM00345 13 72 4.8E-15 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 1.4E-15 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 SUPERFAMILY SSF53383 103 475 9.32E-93 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 Gene3D G3DSA:3.90.1150.10 109 473 1.6E-110 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 Pfam PF00155 Aminotransferase class I and II 117 465 1.5E-32 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 Gene3D G3DSA:3.40.640.10 149 369 1.6E-110 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 4.6E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 4.6E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_14225 a74b65dcc5a88f55c4166a67b1ade5b0 477 SUPERFAMILY SSF46785 3 80 5.75E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 Gene3D G3DSA:3.40.630.10 17 374 3.1E-148 T 01-11-2018 MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 SUPERFAMILY SSF55031 185 298 4.71E-32 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 377 5.1E-128 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 Gene3D G3DSA:3.30.70.360 183 297 3.1E-148 T 01-11-2018 MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 Pfam PF01546 Peptidase family M20/M25/M40 74 385 2.3E-29 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 Pfam PF07687 Peptidase dimerisation domain 187 279 1.3E-14 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 SUPERFAMILY SSF53187 3 389 7.23E-90 T 01-11-2018 MLA2C4_19455 9cec6ad85d98f115ebe0aad02341d14e 403 PIRSF PIRSF005962 1 392 3.0E-133 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 7 469 2.7E-201 T 01-11-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 Pfam PF02378 Phosphotransferase system, EIIC 112 412 4.3E-44 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 SUPERFAMILY SSF55604 8 83 3.27E-19 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 Pfam PF00367 phosphotransferase system, EIIB 11 43 8.6E-15 T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 Gene3D G3DSA:3.30.1360.60 2 80 1.0E-25 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 32 113 1.3E-15 T 01-11-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MLA2C4_03320 c5dd18daff1ddde286a85ad674b5a894 475 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_09530 0f41d586770e97f3c92b58c17aa93b57 441 SUPERFAMILY SSF51556 65 364 1.12E-94 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_09530 0f41d586770e97f3c92b58c17aa93b57 441 SUPERFAMILY SSF51338 10 439 3.56E-32 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_09530 0f41d586770e97f3c92b58c17aa93b57 441 Gene3D G3DSA:2.30.40.10 13 431 1.9E-147 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_09530 0f41d586770e97f3c92b58c17aa93b57 441 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 4 440 43.974 T 01-11-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 MLA2C4_09530 0f41d586770e97f3c92b58c17aa93b57 441 Gene3D G3DSA:3.20.20.140 66 358 1.9E-147 T 01-11-2018 MLA2C4_09530 0f41d586770e97f3c92b58c17aa93b57 441 Pfam PF01979 Amidohydrolase family 62 414 1.4E-73 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 SMART SM01400 10 126 1.4E-82 T 01-11-2018 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 317 51.753 T 01-11-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 5.6E-132 T 01-11-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 SUPERFAMILY SSF53271 75 309 4.88E-68 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 4.6E-25 T 01-11-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 01-11-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 Gene3D G3DSA:3.40.50.2020 153 293 1.3E-127 T 01-11-2018 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 Gene3D G3DSA:3.40.50.2020 13 305 1.3E-127 T 01-11-2018 MLA2C4_00285 6387e58d06a3a50db1ea517e5c8a24b1 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 1.5E-52 T 01-11-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 441 3.6E-27 T 01-11-2018 IPR000014 PAS domain MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 450 576 8.8E-18 T 01-11-2018 IPR000014 PAS domain MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SUPERFAMILY SSF55785 441 568 1.08E-19 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Pfam PF07694 5TMR of 5TMR-LYT 37 136 1.2E-6 T 01-11-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Gene3D G3DSA:1.10.287.130 571 648 9.8E-19 T 01-11-2018 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00387 691 798 1.1E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SUPERFAMILY SSF55874 644 797 3.41E-38 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Gene3D G3DSA:3.30.450.20 224 317 3.6E-11 T 01-11-2018 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Gene3D G3DSA:3.30.565.10 650 799 5.5E-41 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Gene3D G3DSA:3.30.450.20 318 438 8.4E-26 T 01-11-2018 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 729 743 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 782 795 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 747 757 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 776 1.7E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Pfam PF08448 PAS fold 332 437 3.5E-16 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Pfam PF08448 PAS fold 230 310 8.3E-6 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SUPERFAMILY SSF55785 217 316 2.93E-7 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Pfam PF13426 PAS domain 472 569 3.9E-9 T 01-11-2018 IPR000014 PAS domain MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SUPERFAMILY SSF55785 305 430 1.11E-22 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00086 393 435 3.5E-4 T 01-11-2018 IPR001610 PAC motif MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00086 530 570 4.4 T 01-11-2018 IPR001610 PAC motif MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00086 269 309 420.0 T 01-11-2018 IPR001610 PAC motif MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 694 795 1.3E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Gene3D G3DSA:3.30.450.20 439 568 5.3E-23 T 01-11-2018 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 Pfam PF00512 His Kinase A (phospho-acceptor) domain 587 645 1.5E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00388 585 649 4.6E-11 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00091 454 527 0.027 T 01-11-2018 IPR000014 PAS domain MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SMART SM00091 321 386 1.4E-5 T 01-11-2018 IPR000014 PAS domain MLA2C4_16365 78ddb98812af243236acf40f8febfe9a 801 SUPERFAMILY SSF47384 578 646 1.2E-11 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_12985 ac0a3fd15c706f58d36f8936eca4b2c0 142 SUPERFAMILY SSF46689 1 119 2.27E-64 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_12985 ac0a3fd15c706f58d36f8936eca4b2c0 142 Pfam PF13022 Helix-turn-helix of insertion element transposase 3 133 9.3E-49 T 01-11-2018 IPR024978 Homeodomain, phBC6A51-type MLA2C4_12985 ac0a3fd15c706f58d36f8936eca4b2c0 142 Gene3D G3DSA:1.10.10.60 10 108 4.5E-42 T 01-11-2018 MLA2C4_10850 4ef4014076296eeee2f309af33524973 378 SUPERFAMILY SSF56349 65 365 1.27E-69 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_10850 4ef4014076296eeee2f309af33524973 378 Gene3D G3DSA:1.10.150.130 64 159 3.1E-18 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_10850 4ef4014076296eeee2f309af33524973 378 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 77 120 8.2E-7 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_10850 4ef4014076296eeee2f309af33524973 378 Pfam PF00589 Phage integrase family 173 357 1.2E-29 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_10850 4ef4014076296eeee2f309af33524973 378 Gene3D G3DSA:1.10.443.10 160 373 2.6E-56 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_10850 4ef4014076296eeee2f309af33524973 378 Pfam PF14657 Arm DNA-binding domain 12 56 3.4E-15 T 01-11-2018 IPR028259 AP2-like integrase, N-terminal domain MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 SUPERFAMILY SSF46894 128 228 4.82E-30 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 2.4E-26 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 Pfam PF00072 Response regulator receiver domain 4 113 1.5E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 SUPERFAMILY SSF52172 1 130 1.12E-40 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 Gene3D G3DSA:1.10.10.10 130 229 5.0E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 Gene3D G3DSA:3.40.50.2300 1 129 4.8E-37 T 01-11-2018 MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 SMART SM00448 2 112 1.6E-41 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_24260 810aaac1ea6d4f71555db566bc6430dd 229 SMART SM00862 151 227 2.1E-27 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 SUPERFAMILY SSF52402 5 144 2.01E-35 T 01-11-2018 MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 Gene3D G3DSA:3.40.50.620 7 144 2.0E-42 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 Pfam PF00582 Universal stress protein family 5 144 1.6E-36 T 01-11-2018 IPR006016 UspA MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 PIRSF PIRSF006276 1 147 8.9E-22 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 PRINTS PR01438 Universal stress protein signature 5 23 7.3E-19 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 PRINTS PR01438 Universal stress protein signature 104 116 7.3E-19 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_24035 f7e568a2d76c750f0dfa76577908540e 152 PRINTS PR01438 Universal stress protein signature 122 144 7.3E-19 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_14565 28bb15ef6941d02d844870fbc57c776d 152 Gene3D G3DSA:3.40.630.30 2 137 2.2E-16 T 01-11-2018 MLA2C4_14565 28bb15ef6941d02d844870fbc57c776d 152 SUPERFAMILY SSF55729 17 136 5.23E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14565 28bb15ef6941d02d844870fbc57c776d 152 Pfam PF13508 Acetyltransferase (GNAT) domain 49 131 4.2E-10 T 01-11-2018 IPR000182 GNAT domain MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 Gene3D G3DSA:3.40.50.300 288 516 6.9E-42 T 01-11-2018 MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 Pfam PF00005 ABC transporter 20 191 1.9E-24 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 Pfam PF12848 ABC transporter 230 315 6.8E-21 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 SMART SM00382 28 236 1.4E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 SMART SM00382 349 513 1.2E-6 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 Gene3D G3DSA:3.40.50.300 3 285 3.6E-63 T 01-11-2018 MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 SUPERFAMILY SSF52540 316 508 5.16E-36 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 Pfam PF00005 ABC transporter 342 468 1.5E-19 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_28125 37eda899a7bd1c061d7dd19b519236ff 517 SUPERFAMILY SSF52540 4 232 1.55E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01885 0f7fade3b2e41f4b13c0fbb70ec47b49 63 Pfam PF13080 Protein of unknown function (DUF3926) 18 60 1.9E-25 T 01-11-2018 IPR025076 Protein of unknown function DUF3926 MLA2C4_09325 3b61bb616c90e41075f81f394ac177a2 422 Gene3D G3DSA:1.20.1250.20 18 418 1.8E-36 T 01-11-2018 MLA2C4_09325 3b61bb616c90e41075f81f394ac177a2 422 SUPERFAMILY SSF103473 20 419 5.75E-43 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_09325 3b61bb616c90e41075f81f394ac177a2 422 Pfam PF07690 Major Facilitator Superfamily 45 284 2.4E-14 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF00575 S1 RNA binding domain 620 691 8.9E-20 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SUPERFAMILY SSF54211 293 489 3.24E-48 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 692 0.0 T 01-11-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SUPERFAMILY SSF54211 8 144 6.07E-50 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SUPERFAMILY SSF55666 451 549 6.28E-29 T 01-11-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.181 T 01-11-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Gene3D G3DSA:3.30.230.70 1 230 2.5E-84 T 01-11-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SUPERFAMILY SSF54791 556 641 4.93E-24 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Gene3D G3DSA:2.40.50.140 623 693 1.0E-26 T 01-11-2018 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SUPERFAMILY SSF50249 621 703 6.86E-22 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 3.6E-18 T 01-11-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 2.3E-20 T 01-11-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Gene3D G3DSA:3.30.1370.10 551 622 6.8E-21 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 8.7E-15 T 01-11-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Gene3D G3DSA:3.30.230.70 235 550 9.2E-118 T 01-11-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SUPERFAMILY SSF55666 145 235 6.94E-30 T 01-11-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF00013 KH domain 557 615 1.4E-9 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 PIRSF PIRSF005499 2 712 3.6E-301 T 01-11-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF03725 3' exoribonuclease family, domain 2 460 528 1.4E-6 T 01-11-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.0E-16 T 01-11-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SMART SM00322 553 618 1.4E-12 T 01-11-2018 IPR004087 K Homology domain GO:0003676 MLA2C4_19905 87e03bf1ed46bbb8f00f47f563e440c0 712 SMART SM00316 621 691 1.7E-25 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_04700 8b81dee91990c0b50b44ab5fbebe4034 118 Gene3D G3DSA:1.20.1500.10 2 113 9.7E-35 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily MLA2C4_04700 8b81dee91990c0b50b44ab5fbebe4034 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 9.4E-23 T 01-11-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA MLA2C4_04700 8b81dee91990c0b50b44ab5fbebe4034 118 SUPERFAMILY SSF158622 4 113 1.7E-34 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily MLA2C4_04700 8b81dee91990c0b50b44ab5fbebe4034 118 Hamap MF_01526 UPF0342 protein . 2 113 18.816 T 01-11-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 SUPERFAMILY SSF55874 346 495 2.62E-37 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Gene3D G3DSA:3.30.450.20 74 173 4.7E-32 T 01-11-2018 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Pfam PF11346 Protein of unknown function (DUF3149) 1 38 8.4E-11 T 01-11-2018 IPR021494 Protein of unknown function DUF3149 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Gene3D G3DSA:3.30.565.10 350 497 1.1E-39 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 SUPERFAMILY SSF47384 274 345 2.35E-13 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 SMART SM00387 391 497 2.7E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Pfam PF02743 Cache domain 90 201 3.0E-12 T 01-11-2018 IPR033479 Double Cache domain 1 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 286 346 1.5E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 SMART SM00388 284 349 1.7E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Gene3D G3DSA:3.30.450.20 46 225 4.7E-32 T 01-11-2018 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Gene3D G3DSA:1.10.287.130 268 347 6.8E-16 T 01-11-2018 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 495 2.0E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 1.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 1.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 1.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07080 c9b675431ff2edf59ee2b2adf2ff6777 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 1.5E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 01-11-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 149 5.7E-20 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 76 88 5.7E-20 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 5.7E-20 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 ProSitePatterns PS00761 Signal peptidases I signature 3. 135 148 - T 01-11-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 171 1.6E-48 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 SUPERFAMILY SSF51306 27 176 1.44E-44 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 Gene3D G3DSA:2.10.109.10 37 169 7.1E-33 T 01-11-2018 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 ProSitePatterns PS00760 Signal peptidases I lysine active site. 78 90 - T 01-11-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MLA2C4_02475 11b8b14115beaaefedd013d5016976ca 178 Pfam PF00717 Peptidase S24-like 34 99 2.5E-17 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_08365 7a1c5a5fd840e2c5d4647b92da90f5da 82 Pfam PF10819 Protein of unknown function (DUF2564) 5 82 3.9E-35 T 01-11-2018 IPR020314 Uncharacterised protein family YpzA MLA2C4_08365 7a1c5a5fd840e2c5d4647b92da90f5da 82 ProDom PD062992 CYTOSOLIC YPZA BH2151 1 82 7.0E-42 T 01-11-2018 IPR020314 Uncharacterised protein family YpzA MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 SUPERFAMILY SSF100950 2 145 8.05E-45 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 216 4.1E-68 T 01-11-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 SUPERFAMILY SSF75445 125 203 4.58E-24 T 01-11-2018 MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 Gene3D G3DSA:3.40.50.1360 4 216 2.2E-82 T 01-11-2018 MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 Gene3D G3DSA:3.30.70.260 124 200 2.2E-82 T 01-11-2018 MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 220 32.696 T 01-11-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MLA2C4_14785 e0e499ebdc8e150913c7cda5c5cb4a3c 220 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 3 217 1.1E-89 T 01-11-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.146 T 01-11-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.2E-29 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.2E-29 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 1.2E-29 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 1.2E-29 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 453 4.7E-213 T 01-11-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 2.3E-70 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 2.3E-70 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 2.3E-70 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 2.3E-70 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 2.3E-70 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 2.3E-70 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 Gene3D G3DSA:1.20.200.10 120 448 5.0E-198 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 1.6E-23 T 01-11-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 Gene3D G3DSA:1.10.40.30 361 433 5.0E-198 T 01-11-2018 MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 Pfam PF00206 Lyase 7 301 3.8E-83 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 Gene3D G3DSA:1.10.275.10 26 230 5.0E-198 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_24055 d365d57a4690e4af3b65edc38b8a6781 463 SUPERFAMILY SSF48557 7 457 1.21E-153 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_15430 448bed75efa3d335cf0602f8e615ad62 282 Gene3D G3DSA:1.10.3720.10 74 264 1.6E-20 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_15430 448bed75efa3d335cf0602f8e615ad62 282 SUPERFAMILY SSF161098 76 255 8.63E-29 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_15430 448bed75efa3d335cf0602f8e615ad62 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 267 4.5E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.4E-12 T 01-11-2018 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.4E-12 T 01-11-2018 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.4E-12 T 01-11-2018 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.4E-12 T 01-11-2018 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 PIRSF PIRSF000194 1 161 7.2E-61 T 01-11-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 Pfam PF00186 Dihydrofolate reductase 3 160 5.7E-62 T 01-11-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 SUPERFAMILY SSF53597 1 160 1.44E-59 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 01-11-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 MLA2C4_11200 a1bf608db74803c23c55b1e46a9b9e1e 161 Gene3D G3DSA:3.40.430.10 1 161 1.5E-61 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 Gene3D G3DSA:3.30.2330.10 194 278 1.4E-32 T 01-11-2018 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 Gene3D G3DSA:3.60.70.12 3 193 2.5E-71 T 01-11-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 407 144.65 T 01-11-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 Pfam PF01960 ArgJ family 24 407 4.2E-149 T 01-11-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 SUPERFAMILY SSF56266 18 403 3.4E-140 T 01-11-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 34 407 0.0 T 01-11-2018 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 407 2.8E-156 T 01-11-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 MLA2C4_21615 cebcabe8d5c879da729762f7b70f48fd 407 Gene3D G3DSA:3.10.20.340 279 407 7.2E-49 T 01-11-2018 MLA2C4_19740 20e3c5f92a0da0e431a8c965021f7e75 307 Gene3D G3DSA:3.20.20.140 1 306 2.5E-106 T 01-11-2018 MLA2C4_19740 20e3c5f92a0da0e431a8c965021f7e75 307 SUPERFAMILY SSF51556 1 304 2.86E-75 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_19740 20e3c5f92a0da0e431a8c965021f7e75 307 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 305 3.0E-100 T 01-11-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 515 5.3E-270 T 01-11-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 541 661 1.4E-47 T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 366 9.7E-88 T 01-11-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 Gene3D G3DSA:2.70.70.10 527 687 8.9E-64 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 Pfam PF00367 phosphotransferase system, EIIB 442 475 3.4E-12 T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 453 470 - T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 540 663 2.2E-52 T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 Pfam PF02378 Phosphotransferase system, EIIC 13 355 3.7E-100 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 415 499 1.2E-19 T 01-11-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 Gene3D G3DSA:3.30.1360.60 436 516 6.9E-27 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 SUPERFAMILY SSF51261 535 683 2.09E-56 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 SUPERFAMILY SSF55604 442 513 6.41E-20 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_21180 05fd634a0a291ab4707c60584c32f466 687 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 603 615 - T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 SUPERFAMILY SSF51735 7 167 4.82E-49 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 163 1.1E-52 T 01-11-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 285 4.9E-36 T 01-11-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 Gene3D G3DSA:3.40.50.720 1 166 4.0E-50 T 01-11-2018 MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 Gene3D G3DSA:1.10.1040.10 167 291 4.1E-41 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 SUPERFAMILY SSF48179 167 289 1.08E-39 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_21140 99c5c34593da7e89504a641df9c3c613 292 PIRSF PIRSF000103 1 291 1.2E-68 T 01-11-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 Pfam PF00294 pfkB family carbohydrate kinase 23 287 2.1E-52 T 01-11-2018 IPR011611 Carbohydrate kinase PfkB MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 306 2.2E-92 T 01-11-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 PIRSF PIRSF000535 1 307 7.7E-98 T 01-11-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 Gene3D G3DSA:3.40.1190.20 1 307 2.4E-102 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 306 1.1E-100 T 01-11-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MLA2C4_09305 32a0b858ec51c9d83d9d737d44b87481 307 SUPERFAMILY SSF53613 1 285 7.64E-65 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_25540 bdc59908037410765ddfacfc086ea6ed 384 Pfam PF00155 Aminotransferase class I and II 70 378 7.0E-40 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_25540 bdc59908037410765ddfacfc086ea6ed 384 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 382 3.6E-143 T 01-11-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 MLA2C4_25540 bdc59908037410765ddfacfc086ea6ed 384 SUPERFAMILY SSF53383 1 382 1.93E-97 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_25540 bdc59908037410765ddfacfc086ea6ed 384 Gene3D G3DSA:3.40.640.10 63 286 2.4E-148 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_25540 bdc59908037410765ddfacfc086ea6ed 384 Gene3D G3DSA:3.90.1150.10 12 378 2.4E-148 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_16085 6c452688dc9be76cc2b97d2ba9e23643 265 Pfam PF13468 Glyoxalase-like domain 4 193 3.1E-45 T 01-11-2018 IPR025870 Glyoxalase-like domain MLA2C4_16085 6c452688dc9be76cc2b97d2ba9e23643 265 Gene3D G3DSA:3.10.180.10 1 159 5.7E-54 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_16085 6c452688dc9be76cc2b97d2ba9e23643 265 SUPERFAMILY SSF54593 169 242 8.07E-6 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_16085 6c452688dc9be76cc2b97d2ba9e23643 265 Gene3D G3DSA:3.10.180.10 166 252 6.4E-7 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_16085 6c452688dc9be76cc2b97d2ba9e23643 265 SUPERFAMILY SSF54593 2 148 1.2E-7 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_13595 3f76d5e52d7d899b2111ca4929cad85d 159 SUPERFAMILY SSF55961 2 152 1.43E-30 T 01-11-2018 MLA2C4_13595 3f76d5e52d7d899b2111ca4929cad85d 159 Gene3D G3DSA:3.30.530.20 2 158 8.9E-35 T 01-11-2018 IPR023393 START-like domain superfamily MLA2C4_13595 3f76d5e52d7d899b2111ca4929cad85d 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 132 1.0E-8 T 01-11-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 Gene3D G3DSA:1.10.40.30 406 461 6.0E-30 T 01-11-2018 MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 91.928 T 01-11-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 SUPERFAMILY SSF48557 3 458 2.65E-153 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 Gene3D G3DSA:1.10.275.10 1 136 2.6E-57 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 4.8E-34 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 4.8E-34 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 4.8E-34 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 4.8E-34 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 Pfam PF10415 Fumarase C C-terminus 406 458 4.7E-28 T 01-11-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 459 2.0E-234 T 01-11-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 Pfam PF00206 Lyase 11 340 2.3E-115 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_08975 baa369f1ecdfe656aae4418d417bd031 462 Gene3D G3DSA:1.20.200.10 137 404 3.0E-108 T 01-11-2018 MLA2C4_13725 9f4881586a4f515246a6815e2fd65278 362 Gene3D G3DSA:1.10.10.60 59 115 6.1E-10 T 01-11-2018 MLA2C4_13725 9f4881586a4f515246a6815e2fd65278 362 SUPERFAMILY SSF46689 2 52 1.25E-8 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_13725 9f4881586a4f515246a6815e2fd65278 362 SMART SM00342 19 101 4.7E-17 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_13725 9f4881586a4f515246a6815e2fd65278 362 Pfam PF12833 Helix-turn-helix domain 25 101 1.8E-15 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_13725 9f4881586a4f515246a6815e2fd65278 362 SUPERFAMILY SSF46689 56 103 7.17E-8 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_13725 9f4881586a4f515246a6815e2fd65278 362 Gene3D G3DSA:1.10.10.60 1 56 5.0E-15 T 01-11-2018 MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 Gene3D G3DSA:3.40.50.880 1 220 1.4E-76 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 4.5E-99 T 01-11-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 SMART SM01211 1 219 3.2E-139 T 01-11-2018 MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 SUPERFAMILY SSF52317 2 219 2.5E-78 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 202 2.4E-47 T 01-11-2018 MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 46.293 T 01-11-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01770 5aa13c84c3bda1060572b55a4d3eeb65 227 PIRSF PIRSF001586 1 222 1.8E-93 T 01-11-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_02915 1102dd70fdeda1620d56f4ec9f25d8aa 87 Gene3D G3DSA:1.10.1660.10 3 66 8.6E-14 T 01-11-2018 MLA2C4_02915 1102dd70fdeda1620d56f4ec9f25d8aa 87 Pfam PF13411 MerR HTH family regulatory protein 4 48 1.1E-10 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_02915 1102dd70fdeda1620d56f4ec9f25d8aa 87 SUPERFAMILY SSF46955 3 54 1.33E-12 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_15965 6a38991edf721188cc66f1c2930245dd 168 Gene3D G3DSA:3.90.79.10 1 154 2.2E-35 T 01-11-2018 MLA2C4_15965 6a38991edf721188cc66f1c2930245dd 168 Pfam PF00293 NUDIX domain 17 127 1.3E-13 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_15965 6a38991edf721188cc66f1c2930245dd 168 SUPERFAMILY SSF55811 15 150 2.03E-21 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_19360 c87fa2d739738eae958158dac3813f05 423 SUPERFAMILY SSF53383 60 398 1.27E-47 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_19360 c87fa2d739738eae958158dac3813f05 423 Gene3D G3DSA:3.40.640.10 58 271 4.5E-185 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_19360 c87fa2d739738eae958158dac3813f05 423 Gene3D G3DSA:3.90.1150.60 17 411 4.5E-185 T 01-11-2018 MLA2C4_19360 c87fa2d739738eae958158dac3813f05 423 Pfam PF06838 Methionine gamma-lyase 14 414 8.0E-211 T 01-11-2018 IPR009651 Putative methionine gamma-lyase MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Gene3D G3DSA:1.10.8.60 542 624 7.4E-22 T 01-11-2018 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Gene3D G3DSA:3.30.450.20 110 220 8.8E-22 T 01-11-2018 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Gene3D G3DSA:3.30.450.20 224 340 4.4E-17 T 01-11-2018 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Gene3D G3DSA:1.10.10.60 632 686 3.6E-13 T 01-11-2018 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SMART SM00382 389 533 2.2E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SUPERFAMILY SSF55785 121 215 1.05E-15 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Pfam PF02954 Bacterial regulatory protein, Fis family 643 682 1.6E-13 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 393 406 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 583 592 - T 01-11-2018 IPR025944 Sigma-54 interaction domain, conserved site MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 665 685 5.9E-8 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 665 5.9E-8 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SUPERFAMILY SSF46689 583 682 3.09E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 122 228 4.0E-14 T 01-11-2018 IPR000014 PAS domain MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 236 350 5.8E-17 T 01-11-2018 IPR000014 PAS domain MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SMART SM00091 118 184 3.7E-11 T 01-11-2018 IPR000014 PAS domain MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SMART SM00091 237 302 1.0E-6 T 01-11-2018 IPR000014 PAS domain MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SUPERFAMILY SSF52540 368 614 2.38E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 456 471 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Pfam PF00158 Sigma-54 interaction domain 369 537 1.2E-66 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SUPERFAMILY SSF51735 1 83 6.62E-12 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Gene3D G3DSA:3.40.50.300 356 541 4.3E-61 T 01-11-2018 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Gene3D G3DSA:3.40.50.720 1 92 1.5E-6 T 01-11-2018 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 SUPERFAMILY SSF55785 236 336 3.14E-15 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Pfam PF00989 PAS fold 239 340 1.2E-11 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_21795 074cbc9d1c7cf060ba0611a29c7aebf9 690 Pfam PF00989 PAS fold 120 219 1.0E-13 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_25200 bce069f13c0d9f754fb7ceb9ef927d67 441 PIRSF PIRSF002746 1 441 4.0E-145 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_25200 bce069f13c0d9f754fb7ceb9ef927d67 441 Pfam PF02447 GntP family permease 5 439 7.1E-146 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_25200 bce069f13c0d9f754fb7ceb9ef927d67 441 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 441 2.3E-138 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 357 1.6E-111 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 Pfam PF00155 Aminotransferase class I and II 30 352 1.2E-57 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 61.65 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 Gene3D G3DSA:3.90.1150.10 20 351 9.6E-114 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 Gene3D G3DSA:3.40.640.10 43 267 9.6E-114 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 01-11-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MLA2C4_07985 39ffe793768324fbc7695317ec2adcae 370 SUPERFAMILY SSF53383 14 358 1.79E-81 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 Gene3D G3DSA:3.40.50.300 270 492 1.5E-36 T 01-11-2018 MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 ProSitePatterns PS00211 ABC transporters family signature. 423 437 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 SMART SM00382 30 190 1.4E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 SMART SM00382 334 491 0.77 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 Pfam PF00005 ABC transporter 22 146 4.8E-15 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 SUPERFAMILY SSF52540 300 492 3.97E-33 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 SUPERFAMILY SSF52540 3 199 1.65E-33 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 Gene3D G3DSA:3.40.50.300 1 244 7.8E-38 T 01-11-2018 MLA2C4_18260 ef4d5e4b99bfc12fa440b3424f7c466b 492 Pfam PF00005 ABC transporter 327 451 6.3E-17 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_13340 ecbdb2fa7e0c5d2d770fa01eb4a3659b 275 Gene3D G3DSA:2.30.30.40 178 250 4.5E-6 T 01-11-2018 MLA2C4_07865 cce04c4a9fdb62d361c829a58136f8cf 176 Gene3D G3DSA:3.40.80.10 6 174 2.6E-45 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_07865 cce04c4a9fdb62d361c829a58136f8cf 176 SMART SM00644 15 151 1.2E-15 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_07865 cce04c4a9fdb62d361c829a58136f8cf 176 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 151 1.4E-19 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_07865 cce04c4a9fdb62d361c829a58136f8cf 176 SUPERFAMILY SSF55846 15 168 3.53E-34 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_26515 b6dccf990e3b5bf3f623272ebc41091d 395 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 215 380 4.6E-36 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_26515 b6dccf990e3b5bf3f623272ebc41091d 395 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 382 3.2E-88 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_26515 b6dccf990e3b5bf3f623272ebc41091d 395 Gene3D G3DSA:3.30.300.210 231 383 2.1E-39 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_21240 19782c74023e737533f52a0b5d579886 122 SUPERFAMILY SSF55729 6 97 1.8E-12 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21240 19782c74023e737533f52a0b5d579886 122 Pfam PF00583 Acetyltransferase (GNAT) family 35 97 2.1E-8 T 01-11-2018 IPR000182 GNAT domain MLA2C4_21240 19782c74023e737533f52a0b5d579886 122 Gene3D G3DSA:3.40.630.30 18 117 8.6E-12 T 01-11-2018 MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 SUPERFAMILY SSF52922 201 336 3.4E-42 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 Pfam PF02779 Transketolase, pyrimidine binding domain 4 192 1.1E-55 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 SUPERFAMILY SSF52518 2 216 7.36E-66 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 Pfam PF02780 Transketolase, C-terminal domain 206 328 2.3E-43 T 01-11-2018 IPR033248 Transketolase, C-terminal domain MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 Gene3D G3DSA:3.40.50.970 3 204 3.5E-82 T 01-11-2018 MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 Gene3D G3DSA:3.40.50.920 205 337 7.0E-49 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_14695 a5bebf649283b226da7db2bf73260e34 344 SMART SM00861 5 192 4.6E-62 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_07070 08639cda6dcf84a135912b9ee6bcf69a 256 Gene3D G3DSA:3.20.20.370 26 248 1.5E-75 T 01-11-2018 MLA2C4_07070 08639cda6dcf84a135912b9ee6bcf69a 256 Pfam PF04748 Divergent polysaccharide deacetylase 33 247 2.0E-71 T 01-11-2018 IPR006837 Divergent polysaccharide deacetylase MLA2C4_07070 08639cda6dcf84a135912b9ee6bcf69a 256 SUPERFAMILY SSF88713 30 247 1.11E-65 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 12 217 3.3E-23 T 01-11-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 Gene3D G3DSA:3.40.1080.10 6 172 1.7E-12 T 01-11-2018 MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 14 496 6.6E-224 T 01-11-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 SUPERFAMILY SSF100950 6 224 1.81E-61 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 Gene3D G3DSA:3.30.750.70 249 326 7.1E-7 T 01-11-2018 MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 SUPERFAMILY SSF100950 227 496 5.44E-85 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 321 465 5.1E-43 T 01-11-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain MLA2C4_09515 ec5384bbb8a8141d13ce7ddc1a003289 504 Gene3D G3DSA:3.40.1080.20 338 478 8.8E-41 T 01-11-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily MLA2C4_23785 ec3b141dff1f775631f9e61660a1a571 312 SMART SM00382 161 282 0.0075 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23785 ec3b141dff1f775631f9e61660a1a571 312 Pfam PF01695 IstB-like ATP binding protein 154 275 1.0E-12 T 01-11-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MLA2C4_23785 ec3b141dff1f775631f9e61660a1a571 312 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 2.3E-31 T 01-11-2018 IPR009928 Primosomal DnaI, N-terminal MLA2C4_23785 ec3b141dff1f775631f9e61660a1a571 312 Gene3D G3DSA:3.40.50.300 108 304 6.9E-54 T 01-11-2018 MLA2C4_23785 ec3b141dff1f775631f9e61660a1a571 312 SUPERFAMILY SSF52540 136 280 6.6E-19 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 Gene3D G3DSA:1.10.10.2520 144 223 9.8E-32 T 01-11-2018 MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 SUPERFAMILY SSF47090 34 100 2.62E-20 T 01-11-2018 IPR036365 PGBD-like superfamily MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 Pfam PF01471 Putative peptidoglycan binding domain 43 99 2.0E-17 T 01-11-2018 IPR002477 Peptidoglycan binding-like MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 Pfam PF07486 Cell Wall Hydrolase 160 258 1.6E-28 T 01-11-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 32 259 1.2E-101 T 01-11-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 Gene3D G3DSA:2.40.10.420 224 259 3.6E-23 T 01-11-2018 MLA2C4_14590 7abcb0806ec1c11509691033206701f6 259 Gene3D G3DSA:1.10.101.10 28 111 9.7E-22 T 01-11-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Gene3D G3DSA:3.30.110.30 403 476 7.1E-24 T 01-11-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 105 269 2.5E-19 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Gene3D G3DSA:3.30.930.10 3 284 7.6E-108 T 01-11-2018 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 SUPERFAMILY SSF55681 13 277 1.26E-80 T 01-11-2018 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 SUPERFAMILY SSF64586 404 476 9.61E-23 T 01-11-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 409 476 7.7E-23 T 01-11-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 SUPERFAMILY SSF52954 279 401 7.03E-34 T 01-11-2018 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 476 6.0E-189 T 01-11-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Gene3D G3DSA:3.40.50.800 285 400 1.4E-36 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 SMART SM00946 409 476 3.8E-31 T 01-11-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Hamap MF_01571 Proline--tRNA ligase [proS]. 9 476 44.929 T 01-11-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 4.1E-10 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 4.1E-10 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 147 158 4.1E-10 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 67 85 4.1E-10 T 01-11-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MLA2C4_02390 200f1c01c3301b915f654d252bb347f3 476 Pfam PF03129 Anticodon binding domain 291 381 7.1E-21 T 01-11-2018 IPR004154 Anticodon-binding MLA2C4_09635 a2ca4528c4996549fed9fa9be93e535e 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 9.6E-48 T 01-11-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 MLA2C4_09635 a2ca4528c4996549fed9fa9be93e535e 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 1.1E-18 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MLA2C4_09635 a2ca4528c4996549fed9fa9be93e535e 131 SUPERFAMILY SSF53927 2 130 3.68E-48 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_09635 a2ca4528c4996549fed9fa9be93e535e 131 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_09635 a2ca4528c4996549fed9fa9be93e535e 131 Gene3D G3DSA:3.40.140.10 1 131 2.1E-55 T 01-11-2018 MLA2C4_26620 6d9374df287699d931e58d8b82b2e39a 158 Gene3D G3DSA:1.20.1250.20 8 156 7.7E-6 T 01-11-2018 MLA2C4_26620 6d9374df287699d931e58d8b82b2e39a 158 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 13 152 4.2E-64 T 01-11-2018 IPR014203 Sporulation stage V, protein AC MLA2C4_26620 6d9374df287699d931e58d8b82b2e39a 158 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 31 148 3.3E-38 T 01-11-2018 IPR005562 SpoVA MLA2C4_14005 0a814582f10c1d4ff5e752d18700e0c9 333 Pfam PF12395 Protein of unknown function 224 329 6.7E-32 T 01-11-2018 IPR022123 Protein of unknown function DUF3658 MLA2C4_14005 0a814582f10c1d4ff5e752d18700e0c9 333 Pfam PF08874 Domain of unknown function (DUF1835) 66 186 1.5E-29 T 01-11-2018 IPR014973 Protein of unknown function DUF1835 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 SUPERFAMILY SSF101386 362 460 8.29E-23 T 01-11-2018 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 Gene3D G3DSA:1.10.287.1080 229 352 6.5E-46 T 01-11-2018 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 Gene3D G3DSA:1.10.287.1080 356 485 2.3E-44 T 01-11-2018 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 204 9.4E-25 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 392 451 8.7E-7 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 8.3E-29 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 PIRSF PIRSF002845 1 486 1.7E-239 T 01-11-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 SUPERFAMILY SSF101386 232 332 2.62E-25 T 01-11-2018 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 SUPERFAMILY SSF53790 3 263 3.05E-33 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 TIGRFAM TIGR00444 mazG: MazG family protein 239 482 5.0E-101 T 01-11-2018 IPR011551 NTP pyrophosphohydrolase MazG MLA2C4_00315 007bb465a44bd2a57de3855773186bf3 486 Gene3D G3DSA:3.40.1010.10 1 118 1.2E-8 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MLA2C4_28145 ba3641345264500822a37567d7c4e55c 323 Gene3D G3DSA:3.90.550.10 1 204 1.1E-36 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_28145 ba3641345264500822a37567d7c4e55c 323 Pfam PF00535 Glycosyl transferase family 2 6 166 7.1E-34 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_28145 ba3641345264500822a37567d7c4e55c 323 SUPERFAMILY SSF53448 2 225 9.38E-38 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 SUPERFAMILY SSF52540 328 573 2.62E-82 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 Pfam PF00664 ABC transporter transmembrane region 19 291 2.0E-51 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 SMART SM00382 362 554 2.0E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 SUPERFAMILY SSF90123 7 318 9.55E-75 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 Gene3D G3DSA:1.20.1560.10 2 319 1.5E-81 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 Pfam PF00005 ABC transporter 355 501 2.2E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 Gene3D G3DSA:3.40.50.300 328 579 2.4E-79 T 01-11-2018 MLA2C4_19145 f9db2062a42b1c4749d6c71e342046d2 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_02300 911a94810f881292814dc27d61cd0249 106 Pfam PF01910 Thiamine-binding protein 8 96 9.5E-30 T 01-11-2018 IPR002767 Thiamine-binding protein MLA2C4_02300 911a94810f881292814dc27d61cd0249 106 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 7 93 5.9E-16 T 01-11-2018 IPR002767 Thiamine-binding protein MLA2C4_02300 911a94810f881292814dc27d61cd0249 106 Gene3D G3DSA:3.30.70.930 1 106 3.6E-49 T 01-11-2018 IPR029756 MTH1187/YkoF-like MLA2C4_02300 911a94810f881292814dc27d61cd0249 106 SUPERFAMILY SSF89957 3 104 2.62E-32 T 01-11-2018 IPR029756 MTH1187/YkoF-like MLA2C4_15485 26b9eca664670045364c120a4fd688d2 138 SUPERFAMILY SSF55729 50 124 1.48E-13 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15485 26b9eca664670045364c120a4fd688d2 138 Pfam PF13673 Acetyltransferase (GNAT) domain 40 115 1.3E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_15485 26b9eca664670045364c120a4fd688d2 138 Gene3D G3DSA:3.40.630.30 3 120 1.3E-12 T 01-11-2018 MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 SMART SM01121 240 558 4.0E-185 T 01-11-2018 IPR033470 Uncharacterised protein, DhaK domain MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 Pfam PF02734 DAK2 domain 36 200 5.0E-40 T 01-11-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 SMART SM01120 36 201 5.3E-68 T 01-11-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 Pfam PF13684 Dihydroxyacetone kinase family 240 558 2.0E-121 T 01-11-2018 IPR033470 Uncharacterised protein, DhaK domain MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 Gene3D G3DSA:1.25.40.340 6 173 2.3E-10 T 01-11-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 SUPERFAMILY SSF101473 2 200 2.35E-44 T 01-11-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_20150 1891828a5f5119b77848dd6989224e29 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 558 1.9E-209 T 01-11-2018 IPR019986 DAK2 domain-containing protein YloV MLA2C4_20605 350ae0ec216aa7f434e1841595a1f99e 307 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 303 7.1E-91 T 01-11-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MLA2C4_20605 350ae0ec216aa7f434e1841595a1f99e 307 Gene3D G3DSA:1.10.357.140 34 187 6.2E-18 T 01-11-2018 MLA2C4_20605 350ae0ec216aa7f434e1841595a1f99e 307 Pfam PF01040 UbiA prenyltransferase family 41 290 7.5E-55 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MLA2C4_20605 350ae0ec216aa7f434e1841595a1f99e 307 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 01-11-2018 IPR030470 UbiA prenyltransferase conserved site MLA2C4_20605 350ae0ec216aa7f434e1841595a1f99e 307 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 22 306 17.965 T 01-11-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 SMART SM00382 257 401 2.4E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 261 274 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Pfam PF02954 Bacterial regulatory protein, Fis family 511 550 7.9E-10 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Gene3D G3DSA:1.10.8.60 410 489 5.1E-23 T 01-11-2018 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Pfam PF13596 PAS domain 101 201 1.5E-5 T 01-11-2018 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Gene3D G3DSA:3.30.450.20 90 201 2.1E-12 T 01-11-2018 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 324 339 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 516 533 3.2E-9 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 533 553 3.2E-9 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Pfam PF00158 Sigma-54 interaction domain 238 404 1.1E-70 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 451 460 - T 01-11-2018 IPR025944 Sigma-54 interaction domain, conserved site MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 SUPERFAMILY SSF52540 239 480 1.81E-70 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 SUPERFAMILY SSF46689 451 552 1.77E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 SUPERFAMILY SSF55785 94 201 2.62E-9 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Gene3D G3DSA:3.40.50.300 214 409 1.4E-66 T 01-11-2018 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 Gene3D G3DSA:1.10.10.60 490 553 5.4E-14 T 01-11-2018 MLA2C4_15000 1e2b6ae232d473a82524a281901225d4 553 SMART SM00091 98 163 0.0012 T 01-11-2018 IPR000014 PAS domain MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 SUPERFAMILY SSF53187 5 419 1.09E-64 T 01-11-2018 MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 Gene3D G3DSA:3.30.70.360 204 330 4.8E-141 T 01-11-2018 MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 Gene3D G3DSA:3.40.630.10 27 418 4.8E-141 T 01-11-2018 MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 Pfam PF01546 Peptidase family M20/M25/M40 97 415 3.2E-39 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 409 4.5E-117 T 01-11-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 Pfam PF07687 Peptidase dimerisation domain 202 311 2.9E-18 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_11480 4c991ca8583ee6dfcaac6ed893728861 422 SUPERFAMILY SSF55031 203 313 3.29E-14 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_27305 52c1b11065e7d915be32c05a0e6c5af1 233 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 30 231 3.0E-69 T 01-11-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MLA2C4_27305 52c1b11065e7d915be32c05a0e6c5af1 233 SUPERFAMILY SSF52540 50 226 5.58E-41 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27305 52c1b11065e7d915be32c05a0e6c5af1 233 Gene3D G3DSA:3.40.50.300 3 233 1.5E-77 T 01-11-2018 MLA2C4_27305 52c1b11065e7d915be32c05a0e6c5af1 233 Pfam PF13614 AAA domain 61 192 3.3E-15 T 01-11-2018 IPR025669 AAA domain MLA2C4_27120 5b08455a242cc1d522a4c475246726bc 163 Pfam PF12773 Double zinc ribbon 106 157 2.1E-6 T 01-11-2018 IPR025874 Double zinc ribbon MLA2C4_06805 50b304f5a4877a0056eb0204dd70d583 196 Pfam PF12389 Camelysin metallo-endopeptidase 2 193 2.0E-82 T 01-11-2018 IPR022121 Peptidase M73, camelysin MLA2C4_06805 50b304f5a4877a0056eb0204dd70d583 196 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 5.7E-13 T 01-11-2018 IPR023833 Signal peptide, camelysin MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 SMART SM00490 386 466 1.5E-20 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 SMART SM00487 56 235 8.5E-30 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 Gene3D G3DSA:3.40.50.300 270 552 2.3E-52 T 01-11-2018 MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 Gene3D G3DSA:3.40.50.10810 62 261 8.5E-42 T 01-11-2018 IPR038718 SNF2-like, N-terminal domain superfamily MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 Pfam PF00271 Helicase conserved C-terminal domain 360 466 1.9E-20 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 SUPERFAMILY SSF52540 168 518 1.78E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 Pfam PF00176 SNF2 family N-terminal domain 79 332 3.6E-36 T 01-11-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MLA2C4_22120 387dbe59e5e3a09ae25c2fd90427f727 560 SUPERFAMILY SSF52540 16 241 2.91E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 17 222 2.3E-57 T 01-11-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 SUPERFAMILY SSF63862 146 224 1.7E-15 T 01-11-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 SMART SM00983 154 220 1.9E-25 T 01-11-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 Gene3D G3DSA:3.40.50.10240 14 226 4.2E-73 T 01-11-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 34 140 1.1E-19 T 01-11-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 155 219 1.1E-17 T 01-11-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20170 c3e0c1b582d75caeaa5758d2a101b174 226 SUPERFAMILY SSF63999 12 143 2.22E-33 T 01-11-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 PIRSF PIRSF011572 1 257 1.0E-122 T 01-11-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 Gene3D G3DSA:3.30.450.40 1 159 7.1E-68 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 Gene3D G3DSA:1.10.10.10 160 259 6.9E-47 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 5.4E-124 T 01-11-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 149.326 T 01-11-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 Pfam PF06018 CodY GAF-like domain 2 178 3.2E-81 T 01-11-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 Pfam PF08222 CodY helix-turn-helix domain 197 257 1.5E-38 T 01-11-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal MLA2C4_20010 81ca06db1c987b799413bd48e3f5bc5b 259 SUPERFAMILY SSF46785 167 256 1.4E-42 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SMART SM00482 634 841 5.1E-118 T 01-11-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 TIGRFAM TIGR00593 pola: DNA polymerase I 5 877 0.0 T 01-11-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SUPERFAMILY SSF56672 471 877 6.34E-159 T 01-11-2018 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SUPERFAMILY SSF88723 2 169 1.42E-56 T 01-11-2018 IPR029060 PIN-like domain superfamily MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Gene3D G3DSA:3.30.420.10 298 490 5.1E-66 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 169 3.0E-54 T 01-11-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Pfam PF00476 DNA polymerase family A 499 875 3.6E-161 T 01-11-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Gene3D G3DSA:3.40.50.1010 5 278 5.3E-101 T 01-11-2018 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SMART SM00474 301 467 1.1E-12 T 01-11-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 265 4.2E-36 T 01-11-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 626 641 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 692 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 824 837 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 762 773 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 810 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 740 751 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 649 672 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 603 625 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 PRINTS PR00868 DNA-polymerase family A (pol I) signature 703 728 1.2E-81 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 ProSitePatterns PS00447 DNA polymerase family A signature. 703 722 - T 01-11-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Gene3D G3DSA:1.10.150.20 658 801 4.8E-110 T 01-11-2018 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Gene3D G3DSA:1.10.150.20 174 247 5.3E-101 T 01-11-2018 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SMART SM00475 3 262 1.7E-150 T 01-11-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SMART SM00279 173 208 5.0E-17 T 01-11-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SUPERFAMILY SSF47807 171 286 1.18E-33 T 01-11-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Gene3D G3DSA:1.20.1060.10 492 606 5.6E-45 T 01-11-2018 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 Gene3D G3DSA:3.30.70.370 612 873 4.8E-110 T 01-11-2018 MLA2C4_23830 ceea36fc9ef462eab7e0af78d8ed6cbe 877 SUPERFAMILY SSF53098 301 468 3.49E-45 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 Gene3D G3DSA:1.10.10.60 387 467 7.0E-17 T 01-11-2018 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 Gene3D G3DSA:3.30.450.20 9 133 4.0E-8 T 01-11-2018 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 SUPERFAMILY SSF46689 361 465 2.69E-14 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 Gene3D G3DSA:1.10.8.60 319 386 1.1E-22 T 01-11-2018 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 01-11-2018 IPR025944 Sigma-54 interaction domain, conserved site MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 Gene3D G3DSA:3.40.50.300 135 318 1.2E-60 T 01-11-2018 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 Pfam PF02954 Bacterial regulatory protein, Fis family 423 463 5.4E-13 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 2.0E-8 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 466 2.0E-8 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 SUPERFAMILY SSF55785 10 121 4.57E-7 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 Pfam PF00158 Sigma-54 interaction domain 149 314 1.6E-63 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 SMART SM00382 169 311 3.2E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02560 5159c59f1ca5d6331bc4eddfa4f4a066 467 SUPERFAMILY SSF52540 148 390 1.7E-64 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 Gene3D G3DSA:3.10.290.10 326 419 1.3E-31 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 Gene3D G3DSA:3.40.50.620 1 222 1.3E-91 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 Pfam PF01479 S4 domain 356 395 1.2E-8 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 SUPERFAMILY SSF55174 321 417 2.62E-23 T 01-11-2018 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 SMART SM00363 352 410 0.0074 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.458 T 01-11-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 3.9E-29 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 3.9E-29 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 3.9E-29 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 3.9E-29 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 Gene3D G3DSA:1.10.240.10 223 325 2.4E-38 T 01-11-2018 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 417 4.3E-131 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 SUPERFAMILY SSF52374 1 323 7.11E-112 T 01-11-2018 MLA2C4_26385 7257e0764e6d734f8421ad1f652312d6 419 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.2E-81 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 5.2E-40 T 01-11-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 5.2E-40 T 01-11-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 379 395 5.2E-40 T 01-11-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 5.2E-40 T 01-11-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 5.2E-40 T 01-11-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 SUPERFAMILY SSF55681 156 495 1.99E-122 T 01-11-2018 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 PIRSF PIRSF039101 2 499 3.1E-199 T 01-11-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 Gene3D G3DSA:2.40.50.140 9 149 1.5E-44 T 01-11-2018 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 Pfam PF01336 OB-fold nucleic acid binding domain 63 140 5.2E-15 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 Gene3D G3DSA:3.30.930.10 150 494 1.9E-136 T 01-11-2018 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 494 6.6E-82 T 01-11-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 8 497 3.2E-223 T 01-11-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 497 46.263 T 01-11-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MLA2C4_00430 fa9901b9f4b0b4e8625ab73c0d35997f 499 SUPERFAMILY SSF50249 8 149 3.18E-43 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 38.234 T 01-11-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 SUPERFAMILY SSF53067 124 253 1.62E-41 T 01-11-2018 MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 2.7E-87 T 01-11-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 SUPERFAMILY SSF53067 1 122 8.55E-40 T 01-11-2018 MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 Gene3D G3DSA:3.30.420.40 1 88 1.5E-36 T 01-11-2018 MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 Pfam PF03309 Type III pantothenate kinase 3 206 2.9E-75 T 01-11-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MLA2C4_00375 a1806eb73734657df70aa7b28217f30a 262 Gene3D G3DSA:3.30.420.40 89 262 3.2E-65 T 01-11-2018 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 SUPERFAMILY SSF102114 198 433 7.59E-65 T 01-11-2018 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 Pfam PF00919 Uncharacterized protein family UPF0004 67 168 1.2E-30 T 01-11-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 01-11-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 Gene3D G3DSA:3.40.50.12160 66 201 8.2E-35 T 01-11-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 74.176 T 01-11-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 SMART SM00729 211 429 3.8E-66 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 Pfam PF01938 TRAM domain 440 502 8.1E-13 T 01-11-2018 IPR002792 TRAM domain MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 1.6E-161 T 01-11-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 Pfam PF04055 Radical SAM superfamily 215 386 7.1E-33 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 502 2.9E-201 T 01-11-2018 MLA2C4_19725 ad70281ca1abb4f3319328aec6f69dbf 509 Gene3D G3DSA:3.80.30.20 210 443 5.1E-91 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 SUPERFAMILY SSF46785 7 57 7.26E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 SUPERFAMILY SSF54637 76 185 4.16E-26 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 Gene3D G3DSA:1.10.10.10 1 62 2.0E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 Gene3D G3DSA:3.10.129.10 70 189 2.8E-40 T 01-11-2018 MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 Hamap MF_01814 Transcription factor FapR [fapR]. 3 190 41.071 T 01-11-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 Pfam PF03061 Thioesterase superfamily 113 171 3.2E-6 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_20140 7616d0dd0558ed569e7fcca41719aaa5 197 PIRSF PIRSF037733 1 193 1.5E-84 T 01-11-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 MLA2C4_14035 7ebc41211a94dae2bb4e7c8033fc33d9 210 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 122 150 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_14035 7ebc41211a94dae2bb4e7c8033fc33d9 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 148 4.5E-11 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_14035 7ebc41211a94dae2bb4e7c8033fc33d9 210 SUPERFAMILY SSF51161 15 204 8.18E-45 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_14035 7ebc41211a94dae2bb4e7c8033fc33d9 210 Gene3D G3DSA:2.160.10.10 1 210 2.1E-78 T 01-11-2018 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 PIRSF PIRSF005578 1 268 1.5E-104 T 01-11-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 Pfam PF01728 FtsJ-like methyltransferase 62 244 2.5E-17 T 01-11-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 SMART SM00363 6 71 2.3E-8 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 SUPERFAMILY SSF55174 5 71 4.86E-13 T 01-11-2018 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 SUPERFAMILY SSF53335 55 246 9.97E-20 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 Gene3D G3DSA:3.10.290.10 2 64 1.3E-24 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 Pfam PF01479 S4 domain 6 48 1.6E-6 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 Gene3D G3DSA:3.40.50.150 65 279 3.7E-84 T 01-11-2018 MLA2C4_21845 0071100a06034bbd8a4d8e7c274e4a58 279 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 3.1E-93 T 01-11-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 MLA2C4_24710 ac262b6b03c851f3fb3a9a4b168b5ebe 277 Gene3D G3DSA:3.40.50.300 1 254 2.3E-49 T 01-11-2018 MLA2C4_24710 ac262b6b03c851f3fb3a9a4b168b5ebe 277 SMART SM00382 27 206 1.7E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_24710 ac262b6b03c851f3fb3a9a4b168b5ebe 277 Pfam PF00005 ABC transporter 18 151 8.8E-25 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_24710 ac262b6b03c851f3fb3a9a4b168b5ebe 277 SUPERFAMILY SSF52540 2 210 5.12E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03390 e705fef1c5dec75b08b365527cb7b917 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 7.3E-21 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03390 e705fef1c5dec75b08b365527cb7b917 218 Gene3D G3DSA:1.10.3720.10 2 217 1.5E-56 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03390 e705fef1c5dec75b08b365527cb7b917 218 SUPERFAMILY SSF161098 13 199 1.2E-45 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03390 e705fef1c5dec75b08b365527cb7b917 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 1.4E-26 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 Gene3D G3DSA:3.40.50.970 332 539 2.8E-81 T 01-11-2018 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 665 2.1E-300 T 01-11-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 1.2E-157 T 01-11-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 SMART SM00861 355 526 3.7E-66 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 01-11-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 01-11-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 Gene3D G3DSA:3.40.50.970 4 331 9.6E-127 T 01-11-2018 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 SUPERFAMILY SSF52518 342 528 4.75E-69 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 Gene3D G3DSA:3.40.50.920 541 666 4.8E-44 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 3.2E-43 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 Pfam PF02780 Transketolase, C-terminal domain 549 658 4.1E-13 T 01-11-2018 IPR033248 Transketolase, C-terminal domain MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 SUPERFAMILY SSF52518 4 326 6.45E-118 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_19160 9554e902bccd2b756568b61ca5de202b 666 SUPERFAMILY SSF52922 532 666 9.29E-42 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_09370 a54f6131a376e94bc471b85b3ad5b17c 544 Pfam PF01943 Polysaccharide biosynthesis protein 6 321 2.3E-44 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_09370 a54f6131a376e94bc471b85b3ad5b17c 544 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 377 523 3.2E-25 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MLA2C4_09370 a54f6131a376e94bc471b85b3ad5b17c 544 PIRSF PIRSF038958 1 541 2.3E-108 T 01-11-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type MLA2C4_14045 6911eeae592ddb28d0809d0a67106b53 165 Gene3D G3DSA:1.10.10.10 1 100 4.6E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14045 6911eeae592ddb28d0809d0a67106b53 165 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 2.0E-17 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_14045 6911eeae592ddb28d0809d0a67106b53 165 SUPERFAMILY SSF46785 4 163 2.59E-28 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19185 a7371470a72f3775d3bf81af717dac06 312 Gene3D G3DSA:3.40.190.10 131 247 1.5E-73 T 01-11-2018 MLA2C4_19185 a7371470a72f3775d3bf81af717dac06 312 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 6 271 2.0E-72 T 01-11-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 MLA2C4_19185 a7371470a72f3775d3bf81af717dac06 312 Gene3D G3DSA:3.40.190.10 48 279 1.5E-73 T 01-11-2018 MLA2C4_19185 a7371470a72f3775d3bf81af717dac06 312 SMART SM00062 43 289 0.0011 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_19185 a7371470a72f3775d3bf81af717dac06 312 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 48 298 1.2E-66 T 01-11-2018 MLA2C4_19185 a7371470a72f3775d3bf81af717dac06 312 SUPERFAMILY SSF53850 41 307 2.18E-51 T 01-11-2018 MLA2C4_06310 fdf9c4a2cde5664ca9bfda8eed5b8381 265 SUPERFAMILY SSF111331 7 261 4.58E-64 T 01-11-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MLA2C4_06310 fdf9c4a2cde5664ca9bfda8eed5b8381 265 Hamap MF_00361 NAD kinase [nadK]. 1 263 24.637 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MLA2C4_06310 fdf9c4a2cde5664ca9bfda8eed5b8381 265 Gene3D G3DSA:2.60.200.30 102 240 9.0E-97 T 01-11-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MLA2C4_06310 fdf9c4a2cde5664ca9bfda8eed5b8381 265 Gene3D G3DSA:3.40.50.10330 18 262 9.0E-97 T 01-11-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MLA2C4_06310 fdf9c4a2cde5664ca9bfda8eed5b8381 265 Pfam PF01513 ATP-NAD kinase 32 188 2.2E-25 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MLA2C4_20550 96749224c8b76453888acdb512de1367 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 116 1.7E-21 T 01-11-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA MLA2C4_20550 96749224c8b76453888acdb512de1367 149 Gene3D G3DSA:1.20.1500.10 5 127 2.6E-29 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily MLA2C4_20550 96749224c8b76453888acdb512de1367 149 SUPERFAMILY SSF158622 6 127 6.54E-33 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily MLA2C4_12990 aa647a3668d4f4a4c31177259d49fe1e 571 Gene3D G3DSA:3.40.50.300 43 290 7.2E-6 T 01-11-2018 MLA2C4_12990 aa647a3668d4f4a4c31177259d49fe1e 571 Pfam PF17289 Terminase RNaseH-like domain 407 552 1.4E-7 T 01-11-2018 IPR035421 Terminase, large subunit gp17-like MLA2C4_12990 aa647a3668d4f4a4c31177259d49fe1e 571 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 418 553 5.0E-17 T 01-11-2018 IPR006517 Archaeophage PsiM2, terminase large subunit MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 PIRSF PIRSF000193 4 267 3.5E-67 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 SUPERFAMILY SSF48179 164 265 6.29E-26 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 265 3.5E-67 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 3.8E-18 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 SUPERFAMILY SSF51735 6 158 2.87E-28 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 Gene3D G3DSA:3.40.50.720 3 164 1.5E-37 T 01-11-2018 MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 Gene3D G3DSA:1.10.3730.10 165 267 2.5E-30 T 01-11-2018 MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 265 2.3E-30 T 01-11-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_01140 7904d3b36214548ad688e18b1b8bcede 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 267 22.231 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_26305 62a8c38392fa301db4ea476ce0b12c14 107 Gene3D G3DSA:1.10.287.1080 2 102 5.6E-24 T 01-11-2018 MLA2C4_26305 62a8c38392fa301db4ea476ce0b12c14 107 SUPERFAMILY SSF101386 1 104 1.64E-24 T 01-11-2018 MLA2C4_26305 62a8c38392fa301db4ea476ce0b12c14 107 PIRSF PIRSF036521 1 107 1.4E-54 T 01-11-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related MLA2C4_26305 62a8c38392fa301db4ea476ce0b12c14 107 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 103 1.0E-11 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 SUPERFAMILY SSF46955 2 122 5.49E-27 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 Pfam PF13411 MerR HTH family regulatory protein 2 65 4.7E-19 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 5.6E-9 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 5.6E-9 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.6E-9 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 Gene3D G3DSA:1.10.1660.10 1 132 2.2E-31 T 01-11-2018 MLA2C4_24365 cd83157a4ce452bd56ef34e6201440f7 137 SMART SM00422 2 70 3.2E-22 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_10335 948ac2582cb6d70b0a8cb71eb7e0cc4c 138 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 1 138 42.9 T 01-11-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 MLA2C4_10335 948ac2582cb6d70b0a8cb71eb7e0cc4c 138 Gene3D G3DSA:3.10.180.10 1 135 1.9E-40 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_10335 948ac2582cb6d70b0a8cb71eb7e0cc4c 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 7.2E-15 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_10335 948ac2582cb6d70b0a8cb71eb7e0cc4c 138 SUPERFAMILY SSF54593 3 129 1.61E-27 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 SUPERFAMILY SSF81271 364 435 6.54E-10 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 SMART SM00471 38 150 4.6E-8 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 Gene3D G3DSA:3.10.20.30 370 444 1.7E-18 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 SUPERFAMILY SSF81301 201 327 4.41E-12 T 01-11-2018 MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 Pfam PF04607 Region found in RelA / SpoT proteins 240 314 2.5E-5 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 Pfam PF13328 HD domain 24 172 2.6E-35 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 Pfam PF02824 TGS domain 379 435 7.0E-9 T 01-11-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 Gene3D G3DSA:3.30.460.10 190 316 5.7E-9 T 01-11-2018 MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 Gene3D G3DSA:1.10.3210.10 1 188 3.7E-64 T 01-11-2018 MLA2C4_15035 7930a88ebdaa8206a06a2a1f02de39ad 466 SUPERFAMILY SSF109604 5 188 7.22E-58 T 01-11-2018 MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 SMART SM00387 215 327 2.7E-27 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 Gene3D G3DSA:3.30.565.10 192 338 1.3E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 324 3.7E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 3.7E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 305 3.7E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 3.7E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 SUPERFAMILY SSF55874 162 323 2.1E-34 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25170 02db1de7168b2256736d05f5a1b03e26 340 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 216 322 1.6E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_08495 e42304f16b9cbb71d56f72b40f5f656d 39 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 9 32 1.2E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_08495 e42304f16b9cbb71d56f72b40f5f656d 39 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 30 1.4E-9 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 Gene3D G3DSA:2.30.38.10 354 429 7.4E-31 T 01-11-2018 MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 Gene3D G3DSA:3.40.50.980 22 179 2.5E-54 T 01-11-2018 MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 1.8E-14 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 526 1.4E-248 T 01-11-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 SUPERFAMILY SSF56801 6 531 1.15E-139 T 01-11-2018 MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 Gene3D G3DSA:3.40.50.980 181 353 5.6E-60 T 01-11-2018 MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 Pfam PF00501 AMP-binding enzyme 32 435 5.4E-86 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_12200 a021a591522a949556d0cd9e763332d1 538 Gene3D G3DSA:3.30.300.310 431 533 4.3E-32 T 01-11-2018 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 117 156 - T 01-11-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 Gene3D G3DSA:3.30.70.360 187 382 4.0E-173 T 01-11-2018 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 SUPERFAMILY SSF55031 187 377 2.3E-54 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 Pfam PF01546 Peptidase family M20/M25/M40 87 464 1.9E-34 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 463 5.9E-174 T 01-11-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 Gene3D G3DSA:3.30.70.360 206 293 4.0E-173 T 01-11-2018 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 SUPERFAMILY SSF53187 5 467 7.14E-63 T 01-11-2018 MLA2C4_24465 9788ddcb12303c4fd9ccebbf71d41a26 468 Gene3D G3DSA:3.40.630.10 16 466 4.0E-173 T 01-11-2018 MLA2C4_18935 6491bf91cc77a30c086b5300022286a5 312 Gene3D G3DSA:3.10.180.10 67 210 1.5E-123 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18935 6491bf91cc77a30c086b5300022286a5 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 5.9E-33 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18935 6491bf91cc77a30c086b5300022286a5 312 SUPERFAMILY SSF54593 5 278 7.68E-48 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18935 6491bf91cc77a30c086b5300022286a5 312 Gene3D G3DSA:3.10.180.10 7 303 1.5E-123 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 Gene3D G3DSA:3.30.70.260 233 335 4.0E-26 T 01-11-2018 MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 SUPERFAMILY SSF55021 248 333 6.52E-18 T 01-11-2018 MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 SMART SM00382 30 218 1.8E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 Pfam PF09383 NIL domain 263 333 9.9E-17 T 01-11-2018 IPR018449 NIL domain MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 Pfam PF00005 ABC transporter 21 169 1.4E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 SUPERFAMILY SSF52540 1 240 4.43E-85 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 Gene3D G3DSA:3.40.50.300 1 232 6.7E-75 T 01-11-2018 MLA2C4_01020 2bce556e762ccfd01dab9f5b81ae19ce 346 SMART SM00930 260 335 4.8E-23 T 01-11-2018 IPR018449 NIL domain MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 Pfam PF00122 E1-E2 ATPase 136 316 2.7E-50 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 547 4.1E-42 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 470 2.7E-29 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 2.7E-29 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 2.7E-29 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 2.7E-29 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.7E-29 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 2.7E-29 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 85 388 1.7E-95 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 ProSitePatterns PS01229 Hypothetical cof family signature 2. 534 556 - T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 SUPERFAMILY SSF56784 335 633 6.87E-57 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 97 636 1.1E-120 T 01-11-2018 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 SUPERFAMILY SSF81653 138 235 1.83E-24 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 85 636 4.9E-186 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 SUPERFAMILY SSF81665 87 617 3.66E-17 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 Gene3D G3DSA:3.40.1110.10 347 466 1.7E-89 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 Gene3D G3DSA:3.40.50.1000 317 585 1.7E-89 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 108 611 6.7E-84 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00941 Cadmium-transporting ATPase signature 65 77 2.8E-13 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00941 Cadmium-transporting ATPase signature 220 234 2.8E-13 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00941 Cadmium-transporting ATPase signature 140 156 2.8E-13 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00941 Cadmium-transporting ATPase signature 201 217 2.8E-13 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 PRINTS PR00941 Cadmium-transporting ATPase signature 120 140 2.8E-13 T 01-11-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MLA2C4_02460 8b20452695eeac009aaaa4bbc54a6669 641 Gene3D G3DSA:2.70.150.20 129 240 5.9E-35 T 01-11-2018 MLA2C4_09705 46e7112c0dabdf8785b68736b4af9be3 139 SUPERFAMILY SSF54593 3 135 9.35E-28 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_09705 46e7112c0dabdf8785b68736b4af9be3 139 Gene3D G3DSA:3.10.180.10 2 134 1.1E-34 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_09705 46e7112c0dabdf8785b68736b4af9be3 139 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 119 3.7E-20 T 01-11-2018 MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 Gene3D G3DSA:3.40.47.10 1 254 2.6E-105 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 9.3E-40 T 01-11-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 SUPERFAMILY SSF53901 4 251 2.58E-77 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 2.6E-198 T 01-11-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 Gene3D G3DSA:3.40.47.10 256 400 3.7E-56 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 3.9E-62 T 01-11-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 PIRSF PIRSF000447 1 412 9.1E-184 T 01-11-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 SMART SM00825 Beta-ketoacyl synthase 6 412 7.3E-16 T 01-11-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MLA2C4_06185 7ac3042422f811ec234aab3e69ac0d7f 412 SUPERFAMILY SSF53901 214 411 5.6E-77 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Gene3D G3DSA:1.10.260.30 328 446 1.6E-44 T 01-11-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Gene3D G3DSA:3.40.50.300 91 286 9.0E-130 T 01-11-2018 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 SMART SM00962 101 297 4.1E-122 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Gene3D G3DSA:1.20.120.140 6 307 9.0E-130 T 01-11-2018 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 SMART SM00963 2 87 1.4E-33 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.3E-22 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Pfam PF02978 Signal peptide binding domain 329 427 8.7E-34 T 01-11-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 2.6E-190 T 01-11-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 SUPERFAMILY SSF47446 329 430 1.8E-37 T 01-11-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 445 35.877 T 01-11-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 SUPERFAMILY SSF52540 43 355 5.31E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 SMART SM00382 100 302 2.9E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_20095 290f8d50c6888b1f21cb5c7ac7a62a7f 449 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 6.8E-80 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 3 488 79.521 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 PIRSF PIRSF000110 1 490 2.8E-188 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 189 5.6E-61 T 01-11-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 Gene3D G3DSA:3.40.50.720 2 177 2.5E-59 T 01-11-2018 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 SUPERFAMILY SSF55347 184 487 3.6E-104 T 01-11-2018 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 SUPERFAMILY SSF51735 2 185 1.61E-62 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 487 3.6E-177 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 Gene3D G3DSA:3.30.360.10 178 489 2.3E-114 T 01-11-2018 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 486 3.8E-105 T 01-11-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 8.9E-43 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 8.9E-43 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 8.9E-43 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 8.9E-43 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_17730 328fd74f2fddb9bf1031a476900d35c0 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 8.9E-43 T 01-11-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MLA2C4_20370 026b502d9376495d4e9015dfcb14d8fe 255 SMART SM00363 179 241 2.0E-11 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_20370 026b502d9376495d4e9015dfcb14d8fe 255 Gene3D G3DSA:3.10.290.10 174 229 1.2E-10 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_20370 026b502d9376495d4e9015dfcb14d8fe 255 Gene3D G3DSA:3.30.1370.160 2 77 3.9E-27 T 01-11-2018 MLA2C4_20370 026b502d9376495d4e9015dfcb14d8fe 255 Pfam PF01479 S4 domain 180 224 4.5E-8 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_20370 026b502d9376495d4e9015dfcb14d8fe 255 SUPERFAMILY SSF55174 34 252 2.22E-38 T 01-11-2018 MLA2C4_20370 026b502d9376495d4e9015dfcb14d8fe 255 Gene3D G3DSA:3.30.70.330 78 163 6.1E-29 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MLA2C4_09710 cccd49ec4f47a548cea81f40ad7cbbe3 337 Pfam PF13524 Glycosyl transferases group 1 224 325 3.7E-21 T 01-11-2018 MLA2C4_09710 cccd49ec4f47a548cea81f40ad7cbbe3 337 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 88 160 2.8E-20 T 01-11-2018 IPR024542 Domain of unknown function DUF3880 MLA2C4_15370 e8aeccff9115dfa3029acc96ac98ef0a 290 SMART SM00382 28 206 3.1E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15370 e8aeccff9115dfa3029acc96ac98ef0a 290 Gene3D G3DSA:3.40.50.300 1 242 1.6E-42 T 01-11-2018 MLA2C4_15370 e8aeccff9115dfa3029acc96ac98ef0a 290 Pfam PF00005 ABC transporter 20 156 2.1E-20 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_15370 e8aeccff9115dfa3029acc96ac98ef0a 290 SUPERFAMILY SSF52540 3 221 2.76E-42 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15370 e8aeccff9115dfa3029acc96ac98ef0a 290 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_20085 55a3ea6a781956a5b176c020de2a6f73 75 Pfam PF13083 KH domain 2 74 7.6E-23 T 01-11-2018 MLA2C4_20085 55a3ea6a781956a5b176c020de2a6f73 75 Gene3D G3DSA:3.30.300.20 1 72 2.5E-6 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_20085 55a3ea6a781956a5b176c020de2a6f73 75 SUPERFAMILY SSF54814 15 58 1.96E-7 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MLA2C4_20085 55a3ea6a781956a5b176c020de2a6f73 75 Hamap MF_00088 UPF0109 protein . 1 75 21.45 T 01-11-2018 IPR020627 Uncharacterised protein family UPF0109 MLA2C4_28315 ac9550ffbc0b43caa76fa82e635130c0 167 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 9 167 2.3E-67 T 01-11-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MLA2C4_28315 ac9550ffbc0b43caa76fa82e635130c0 167 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 9 167 30.048 T 01-11-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MLA2C4_28315 ac9550ffbc0b43caa76fa82e635130c0 167 SUPERFAMILY SSF75217 10 165 5.56E-60 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases MLA2C4_28315 ac9550ffbc0b43caa76fa82e635130c0 167 Pfam PF02590 Predicted SPOUT methyltransferase 10 166 1.7E-56 T 01-11-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MLA2C4_28315 ac9550ffbc0b43caa76fa82e635130c0 167 PIRSF PIRSF004505 9 167 7.3E-52 T 01-11-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MLA2C4_28315 ac9550ffbc0b43caa76fa82e635130c0 167 Gene3D G3DSA:3.40.1280.10 9 167 7.4E-65 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MLA2C4_10630 5ffc4af5251d48b8bc56be5c3906cd91 123 Gene3D G3DSA:2.60.120.10 2 123 2.3E-9 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_10630 5ffc4af5251d48b8bc56be5c3906cd91 123 SUPERFAMILY SSF51182 16 97 3.96E-9 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 Pfam PF01546 Peptidase family M20/M25/M40 70 374 5.4E-34 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 SUPERFAMILY SSF53187 4 377 9.43E-83 T 01-11-2018 MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 Gene3D G3DSA:3.40.630.10 12 362 2.9E-136 T 01-11-2018 MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 SUPERFAMILY SSF55031 179 287 6.41E-31 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 PIRSF PIRSF005962 1 380 7.5E-129 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 Gene3D G3DSA:3.30.70.360 178 292 2.9E-136 T 01-11-2018 MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 Pfam PF07687 Peptidase dimerisation domain 179 274 1.0E-12 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_19065 0b84a99adb8522a35b7b2c401235316d 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 12 364 6.3E-120 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 1.8E-149 T 01-11-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 7.1E-27 T 01-11-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 Pfam PF01938 TRAM domain 391 427 3.3E-6 T 01-11-2018 IPR002792 TRAM domain MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 SMART SM00729 143 361 2.5E-58 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 Gene3D G3DSA:3.80.30.20 140 375 3.6E-85 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 9.8E-141 T 01-11-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 SUPERFAMILY SSF102114 119 365 1.31E-56 T 01-11-2018 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 01-11-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 Gene3D G3DSA:3.40.50.12160 3 134 4.2E-26 T 01-11-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MLA2C4_22510 e9ec12de36a49b485ade8723e75ace62 450 Pfam PF04055 Radical SAM superfamily 149 319 3.3E-27 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_22405 2237503a8bc1e4bc3776a5d942cd27f7 251 Pfam PF14181 YqfQ-like protein 35 251 1.3E-51 T 01-11-2018 IPR025571 YqfQ-like protein MLA2C4_12245 e1f794b8e3c9934ab90591a38481dca1 176 Pfam PF05163 DinB family 7 170 2.4E-30 T 01-11-2018 IPR007837 DNA damage-inducible protein DinB MLA2C4_12245 e1f794b8e3c9934ab90591a38481dca1 176 Gene3D G3DSA:1.20.120.450 1 169 6.7E-41 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_12245 e1f794b8e3c9934ab90591a38481dca1 176 SUPERFAMILY SSF109854 7 165 3.11E-28 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_18815 c1e75a815c6cd50b87c128d62de11ad2 241 Gene3D G3DSA:3.20.20.370 34 241 2.6E-71 T 01-11-2018 MLA2C4_18815 c1e75a815c6cd50b87c128d62de11ad2 241 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 46 237 1.9E-73 T 01-11-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB MLA2C4_18815 c1e75a815c6cd50b87c128d62de11ad2 241 SUPERFAMILY SSF88713 37 238 7.56E-66 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_18815 c1e75a815c6cd50b87c128d62de11ad2 241 Pfam PF01522 Polysaccharide deacetylase 46 166 1.7E-34 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 SUPERFAMILY SSF55021 178 279 8.33E-23 T 01-11-2018 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 Pfam PF00800 Prephenate dehydratase 4 185 1.5E-60 T 01-11-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 Gene3D G3DSA:3.40.190.10 84 173 2.5E-56 T 01-11-2018 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 Gene3D G3DSA:3.40.190.10 6 181 2.5E-56 T 01-11-2018 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 PIRSF PIRSF001500 1 282 3.0E-68 T 01-11-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 228 235 - T 01-11-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 SUPERFAMILY SSF53850 3 186 1.4E-54 T 01-11-2018 MLA2C4_23120 121f41fd551a1c36475f344a36d03cab 283 Gene3D G3DSA:3.30.70.260 193 282 7.4E-24 T 01-11-2018 MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 Gene3D G3DSA:1.10.10.10 1 144 5.4E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 5.3E-5 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 5.3E-5 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 SUPERFAMILY SSF46785 8 142 7.86E-28 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 Pfam PF12802 MarR family 35 92 1.6E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_13265 c2f94128dac475f5001072f5b33f3fa9 160 SMART SM00347 29 129 2.1E-16 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 775 859 1.69E-29 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1479 1563 3.73E-29 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.10 321 413 5.9E-15 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49401 169 303 3.35E-26 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49401 35 157 1.49E-19 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 951 1035 1.77E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1039 1123 1.96E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 2182 2266 3.53E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 421 506 2.55E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 687 771 1.75E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1567 1650 5.49E-24 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2627 2659 9.1E-5 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1280 34 313 5.1E-101 T 01-11-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 336 394 4.71E-7 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1303 1387 1.45E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1742 1826 1.67E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 863 947 1.63E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.740 160 312 5.1E-101 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 510 595 1.41E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1215 1299 3.92E-29 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 2358 2442 1.69E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1127 1211 4.71E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 599 683 1.59E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 424 505 3.3E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 953 1034 1.0E-21 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 2184 2265 3.5E-23 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1920 2001 3.8E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1041 1122 3.1E-24 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 601 682 3.3E-24 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 2008 2089 1.8E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1129 1210 1.9E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1832 1913 1.6E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1217 1298 2.6E-23 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 2272 2353 1.3E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 2096 2177 2.6E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1744 1825 5.8E-21 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1393 1474 4.0E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 513 594 1.0E-21 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 2448 2529 7.0E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 777 858 1.4E-23 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 2360 2441 6.7E-24 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 865 946 2.6E-20 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1656 1737 7.0E-23 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1481 1562 4.3E-23 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1569 1649 1.6E-17 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 689 770 1.0E-22 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05738 Cna protein B-type domain 1305 1386 2.8E-20 T 01-11-2018 IPR008454 Collagen-binding surface protein Cna-like, B-type domain MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1654 1738 1.28E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 2095 2182 4.1E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1655 1742 8.5E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1303 1391 1.5E-24 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 952 1039 2.6E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 420 511 8.1E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1128 1216 2.5E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 777 863 1.6E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 864 951 9.8E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1217 1302 4.3E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1919 2006 1.4E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 599 687 2.2E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 688 776 3.5E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 2447 2545 7.4E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 2271 2358 7.1E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1831 1918 2.7E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1480 1567 3.7E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1392 1479 1.5E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1743 1830 1.0E-24 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 512 598 2.2E-25 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 2183 2270 4.1E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 2359 2446 2.2E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1040 1127 1.6E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 2007 2094 3.4E-26 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Gene3D G3DSA:2.60.40.1140 1568 1654 8.5E-20 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 2094 2178 1.39E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 2006 2090 1.9E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1830 1914 2.35E-28 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1391 1475 2.35E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 Pfam PF05737 Collagen binding domain 171 297 6.0E-22 T 01-11-2018 IPR008456 Collagen binding domain GO:0005518 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 1919 2002 8.24E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 2446 2531 1.2E-27 T 01-11-2018 MLA2C4_27740 fc6dff666937132e8d9d713700231941 2660 SUPERFAMILY SSF49478 2270 2354 1.43E-27 T 01-11-2018 MLA2C4_17825 e65e7dd3f94e642536e163c5ac9fce7e 107 Pfam PF01638 HxlR-like helix-turn-helix 15 102 4.8E-38 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_17825 e65e7dd3f94e642536e163c5ac9fce7e 107 Gene3D G3DSA:1.10.10.10 1 106 2.7E-42 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17825 e65e7dd3f94e642536e163c5ac9fce7e 107 SUPERFAMILY SSF46785 4 103 2.27E-35 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 Gene3D G3DSA:1.10.10.10 1 73 4.9E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 269 2.4E-119 T 01-11-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 73 5.0E-31 T 01-11-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 Pfam PF00156 Phosphoribosyl transferase domain 107 264 2.8E-23 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 SUPERFAMILY SSF46785 2 74 2.99E-27 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 1.9E-32 T 01-11-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 SUPERFAMILY SSF53271 91 269 1.04E-40 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_00265 5497c2c8f2e23894f13af197b43749da 282 Gene3D G3DSA:3.40.50.2020 75 272 1.1E-57 T 01-11-2018 MLA2C4_19680 0afcc6806ce9ae006bcc84dc03ed7c63 927 Pfam PF00350 Dynamin family 380 516 1.5E-10 T 01-11-2018 IPR022812 Dynamin superfamily MLA2C4_19680 0afcc6806ce9ae006bcc84dc03ed7c63 927 SUPERFAMILY SSF52540 375 607 7.67E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19680 0afcc6806ce9ae006bcc84dc03ed7c63 927 Gene3D G3DSA:3.40.50.300 380 602 2.1E-24 T 01-11-2018 MLA2C4_19680 0afcc6806ce9ae006bcc84dc03ed7c63 927 Gene3D G3DSA:1.25.40.10 28 175 8.8E-11 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_19680 0afcc6806ce9ae006bcc84dc03ed7c63 927 SUPERFAMILY SSF48452 46 169 7.59E-12 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 Pfam PF00453 Ribosomal protein L20 3 109 8.1E-51 T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-13 T 01-11-2018 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.4E-51 T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 Gene3D G3DSA:1.10.1900.20 56 118 2.4E-29 T 01-11-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 SUPERFAMILY SSF74731 2 116 5.49E-51 T 01-11-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 Gene3D G3DSA:1.10.720.90 2 55 5.5E-27 T 01-11-2018 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.679 T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-41 T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-41 T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23760 98c71c86f2e2ceaa085ecd5af1facfa2 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-41 T 01-11-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_24150 2497c2058ea6ef57846252a934ba4b46 380 Gene3D G3DSA:3.40.640.10 13 255 1.4E-130 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_24150 2497c2058ea6ef57846252a934ba4b46 380 Gene3D G3DSA:3.90.1150.10 2 370 1.4E-130 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_24150 2497c2058ea6ef57846252a934ba4b46 380 PIRSF PIRSF005572 1 378 5.5E-115 T 01-11-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MLA2C4_24150 2497c2058ea6ef57846252a934ba4b46 380 Pfam PF00266 Aminotransferase class-V 2 364 4.1E-75 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_24150 2497c2058ea6ef57846252a934ba4b46 380 SUPERFAMILY SSF53383 1 372 1.65E-100 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_23635 a253a7979b72dc9afc80f21529ee4251 235 Pfam PF05031 Iron Transport-associated domain 31 146 1.0E-38 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23635 a253a7979b72dc9afc80f21529ee4251 235 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 205 233 2.4E-16 T 01-11-2018 IPR017502 Sortase B cell surface sorting signal MLA2C4_23635 a253a7979b72dc9afc80f21529ee4251 235 Gene3D G3DSA:2.60.40.1850 24 154 4.7E-45 T 01-11-2018 MLA2C4_23635 a253a7979b72dc9afc80f21529ee4251 235 SUPERFAMILY SSF158911 17 157 5.49E-44 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_23635 a253a7979b72dc9afc80f21529ee4251 235 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 1 234 4.1E-93 T 01-11-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 MLA2C4_23635 a253a7979b72dc9afc80f21529ee4251 235 SMART SM00725 32 153 1.5E-44 T 01-11-2018 IPR006635 NEAT domain MLA2C4_13370 13ab2530bbacf7643eed3fb9403f8127 286 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 26 254 3.7E-23 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_13370 13ab2530bbacf7643eed3fb9403f8127 286 SUPERFAMILY SSF56784 20 285 5.63E-29 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_13370 13ab2530bbacf7643eed3fb9403f8127 286 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 24 283 4.7E-23 T 01-11-2018 IPR006380 Sucrose-phosphatase-like, N-terminal MLA2C4_13370 13ab2530bbacf7643eed3fb9403f8127 286 Gene3D G3DSA:3.40.50.1000 143 286 1.5E-20 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_13370 13ab2530bbacf7643eed3fb9403f8127 286 Gene3D G3DSA:3.40.50.1000 4 142 3.2E-35 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_27540 262c1ec48e25ed34f3ea5705ff7a2d7b 128 Pfam PF07681 DoxX 5 93 1.0E-20 T 01-11-2018 IPR032808 DoxX family MLA2C4_00755 fa26a9fcf000bb97cd454396de6e4d85 120 Gene3D G3DSA:3.30.420.100 5 120 5.7E-48 T 01-11-2018 MLA2C4_00755 fa26a9fcf000bb97cd454396de6e4d85 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.937 T 01-11-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00755 fa26a9fcf000bb97cd454396de6e4d85 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.6E-49 T 01-11-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00755 fa26a9fcf000bb97cd454396de6e4d85 120 SUPERFAMILY SSF53137 7 118 3.49E-56 T 01-11-2018 MLA2C4_00755 fa26a9fcf000bb97cd454396de6e4d85 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 6.8E-53 T 01-11-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_09985 9817e5e89a247bc8e664dc940db7fe18 290 SUPERFAMILY SSF81301 1 134 1.01E-48 T 01-11-2018 MLA2C4_09985 9817e5e89a247bc8e664dc940db7fe18 290 Gene3D G3DSA:3.30.460.10 9 148 4.7E-56 T 01-11-2018 MLA2C4_09985 9817e5e89a247bc8e664dc940db7fe18 290 Gene3D G3DSA:1.20.120.330 149 288 6.4E-50 T 01-11-2018 MLA2C4_09985 9817e5e89a247bc8e664dc940db7fe18 290 Pfam PF04439 Streptomycin adenylyltransferase 1 279 4.3E-126 T 01-11-2018 IPR007530 Aminoglycoside 6-adenylyltransferase MLA2C4_09985 9817e5e89a247bc8e664dc940db7fe18 290 PIRSF PIRSF000812 1 285 2.2E-122 T 01-11-2018 IPR007530 Aminoglycoside 6-adenylyltransferase MLA2C4_09985 9817e5e89a247bc8e664dc940db7fe18 290 SUPERFAMILY SSF81631 137 280 3.3E-57 T 01-11-2018 MLA2C4_08490 b04c23d922004c209ef9bbb4ae2adc49 155 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 124 1.1E-8 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_08490 b04c23d922004c209ef9bbb4ae2adc49 155 SUPERFAMILY SSF54593 1 129 2.34E-22 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_08490 b04c23d922004c209ef9bbb4ae2adc49 155 Gene3D G3DSA:3.10.180.10 5 154 3.1E-25 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18940 ecc3d9c615e8080977ecb2c0063ddb55 492 Pfam PF00474 Sodium:solute symporter family 33 431 9.4E-109 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_18940 ecc3d9c615e8080977ecb2c0063ddb55 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 486 9.2E-224 T 01-11-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MLA2C4_18940 ecc3d9c615e8080977ecb2c0063ddb55 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 431 4.0E-101 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_18940 ecc3d9c615e8080977ecb2c0063ddb55 492 Gene3D G3DSA:1.20.1730.10 21 491 3.1E-103 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 Gene3D G3DSA:3.40.50.720 148 286 4.2E-113 T 01-11-2018 MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 Pfam PF00107 Zinc-binding dehydrogenase 174 297 1.4E-23 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 SUPERFAMILY SSF51735 137 305 1.01E-36 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 133 8.1E-30 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 01-11-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 Gene3D G3DSA:3.90.180.10 27 334 4.2E-113 T 01-11-2018 MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 SMART SM00829 9 335 9.0E-8 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_11330 a15d3eb31e9e591c2f5b21286752b0e4 345 SUPERFAMILY SSF50129 1 179 5.93E-48 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_27385 611e0a8358f4d2cb2107e1500755310c 504 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 7 483 17.154 T 01-11-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MLA2C4_27385 611e0a8358f4d2cb2107e1500755310c 504 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 481 3.1E-114 T 01-11-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MLA2C4_27385 611e0a8358f4d2cb2107e1500755310c 504 Pfam PF00361 Proton-conducting membrane transporter 127 425 4.6E-70 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_11995 861226951f9f50fc1d15c51f5867b287 83 Pfam PF13135 Protein of unknown function (DUF3947) 2 83 4.8E-44 T 01-11-2018 IPR025039 Protein of unknown function DUF3947 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Gene3D G3DSA:3.30.450.20 62 273 1.3E-35 T 01-11-2018 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 SUPERFAMILY SSF58104 323 659 1.83E-72 T 01-11-2018 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 1.2E-5 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 511 540 1.2E-5 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 SMART SM00283 384 659 2.3E-74 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Gene3D G3DSA:1.10.287.950 362 659 2.5E-70 T 01-11-2018 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 432 611 1.4E-44 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Gene3D G3DSA:3.30.450.20 72 183 1.3E-35 T 01-11-2018 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Gene3D G3DSA:1.10.8.500 302 355 1.5E-11 T 01-11-2018 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 SUPERFAMILY SSF103190 98 190 1.41E-12 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Pfam PF00672 HAMP domain 303 352 5.1E-14 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 Pfam PF02743 Cache domain 47 266 1.0E-28 T 01-11-2018 IPR033479 Double Cache domain 1 MLA2C4_03060 06af7b24c49a8489361e7bfa5a747814 660 SMART SM00304 303 355 7.6E-15 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26640 fd068f13aeae906bd0a7b517f92192be 289 Gene3D G3DSA:3.30.240.20 84 157 3.9E-24 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_26640 fd068f13aeae906bd0a7b517f92192be 289 Gene3D G3DSA:3.30.240.20 173 231 4.2E-13 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_26640 fd068f13aeae906bd0a7b517f92192be 289 Pfam PF04239 Protein of unknown function (DUF421) 92 206 1.9E-32 T 01-11-2018 IPR007353 Protein of unknown function DUF421 MLA2C4_26640 fd068f13aeae906bd0a7b517f92192be 289 Pfam PF07870 Protein of unknown function (DUF1657) 240 283 4.3E-15 T 01-11-2018 IPR012452 Protein of unknown function DUF1657 MLA2C4_03410 50621a5898f895f265b035dcf0e3ef33 161 Pfam PF01230 HIT domain 31 121 1.5E-18 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_03410 50621a5898f895f265b035dcf0e3ef33 161 SUPERFAMILY SSF54197 18 149 3.4E-32 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_03410 50621a5898f895f265b035dcf0e3ef33 161 Gene3D G3DSA:3.30.428.10 9 157 1.6E-32 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_03410 50621a5898f895f265b035dcf0e3ef33 161 PRINTS PR00332 Histidine triad family signature 21 37 2.0E-6 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_03410 50621a5898f895f265b035dcf0e3ef33 161 PRINTS PR00332 Histidine triad family signature 42 60 2.0E-6 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_03410 50621a5898f895f265b035dcf0e3ef33 161 PRINTS PR00332 Histidine triad family signature 107 117 2.0E-6 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_20500 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.023 T 01-11-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20500 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.8E-28 T 01-11-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20500 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 SUPERFAMILY SSF57829 1 55 5.31E-22 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MLA2C4_20500 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 Pfam PF01783 Ribosomal L32p protein family 2 57 4.9E-27 T 01-11-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_10220 e43c7e8aabeb5dc93aaaaa8afc4e77bd 175 Gene3D G3DSA:1.20.120.450 3 170 4.3E-41 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_10220 e43c7e8aabeb5dc93aaaaa8afc4e77bd 175 Pfam PF04978 Protein of unknown function (DUF664) 20 165 4.3E-13 T 01-11-2018 IPR007061 Protein of unknown function DUF664 MLA2C4_10220 e43c7e8aabeb5dc93aaaaa8afc4e77bd 175 SUPERFAMILY SSF109854 3 167 1.48E-38 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 SMART SM00052 635 881 3.3E-115 T 01-11-2018 IPR001633 EAL domain MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 461 623 2.8E-49 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 SMART SM00091 341 407 7.6E-4 T 01-11-2018 IPR000014 PAS domain MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Pfam PF00563 EAL domain 642 876 8.7E-73 T 01-11-2018 IPR001633 EAL domain MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Gene3D G3DSA:3.30.450.20 330 451 8.9E-18 T 01-11-2018 MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 SUPERFAMILY SSF141868 640 888 2.22E-86 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Gene3D G3DSA:3.20.20.450 639 890 1.6E-96 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 SUPERFAMILY SSF55785 335 451 2.09E-16 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Pfam PF00989 PAS fold 342 450 9.9E-9 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Pfam PF00990 Diguanylate cyclase, GGDEF domain 464 621 4.1E-55 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Pfam PF13321 Domain of unknown function (DUF4084) 1 304 2.6E-190 T 01-11-2018 IPR025152 Domain of unknown function DUF4084 MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 338 458 4.0E-12 T 01-11-2018 IPR000014 PAS domain MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 SUPERFAMILY SSF55073 469 627 8.63E-55 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 Gene3D G3DSA:3.30.70.270 458 638 1.5E-66 T 01-11-2018 MLA2C4_27690 214e1fc6b30be4397ae7064fd1edea56 892 SMART SM00267 453 625 9.7E-76 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27195 b20800df4c8caab5ae8de9c962f2dfd7 260 Pfam PF13057 Protein of unknown function (DUF3919) 37 254 1.2E-42 T 01-11-2018 IPR025031 Protein of unknown function DUF3919 MLA2C4_27795 07b05ab165139b62745fa1c49baceb26 290 SUPERFAMILY SSF52768 12 289 5.76E-87 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily MLA2C4_27795 07b05ab165139b62745fa1c49baceb26 290 TIGRFAM TIGR01230 agmatinase: agmatinase 10 286 1.5E-114 T 01-11-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 MLA2C4_27795 07b05ab165139b62745fa1c49baceb26 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 01-11-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MLA2C4_27795 07b05ab165139b62745fa1c49baceb26 290 Gene3D G3DSA:3.40.800.10 16 289 5.6E-95 T 01-11-2018 MLA2C4_27795 07b05ab165139b62745fa1c49baceb26 290 PIRSF PIRSF036979 1 290 2.5E-103 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_27795 07b05ab165139b62745fa1c49baceb26 290 Pfam PF00491 Arginase family 23 285 1.3E-79 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_04720 0db09c6577beec6b32b8fa093f504603 252 Pfam PF03306 Alpha-acetolactate decarboxylase 20 237 1.6E-88 T 01-11-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 MLA2C4_04720 0db09c6577beec6b32b8fa093f504603 252 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 18 249 3.1E-97 T 01-11-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 MLA2C4_04720 0db09c6577beec6b32b8fa093f504603 252 Gene3D G3DSA:3.30.1330.80 20 236 8.5E-87 T 01-11-2018 MLA2C4_04720 0db09c6577beec6b32b8fa093f504603 252 SUPERFAMILY SSF117856 18 249 6.8E-87 T 01-11-2018 MLA2C4_04720 0db09c6577beec6b32b8fa093f504603 252 PIRSF PIRSF001332 4 250 3.0E-104 T 01-11-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 MLA2C4_04720 0db09c6577beec6b32b8fa093f504603 252 Gene3D G3DSA:3.30.1330.80 95 217 8.5E-87 T 01-11-2018 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 Gene3D G3DSA:3.60.120.10 1 472 1.1E-172 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 471 4.4E-180 T 01-11-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 PRINTS PR00095 Anthranilate synthase component I signature 420 434 6.6E-24 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 PRINTS PR00095 Anthranilate synthase component I signature 405 419 6.6E-24 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 PRINTS PR00095 Anthranilate synthase component I signature 311 324 6.6E-24 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 PRINTS PR00095 Anthranilate synthase component I signature 325 338 6.6E-24 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 Pfam PF00425 chorismate binding enzyme 210 463 1.4E-101 T 01-11-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 SUPERFAMILY SSF56322 16 471 8.11E-159 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_06490 47eab4ae2b9c8c222e6205d4a69422b4 472 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 159 2.7E-35 T 01-11-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 Pfam PF00574 Clp protease 14 192 2.6E-83 T 01-11-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 42.486 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 Gene3D G3DSA:3.90.226.10 1 193 1.4E-77 T 01-11-2018 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 7.0E-50 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 7.0E-50 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 7.0E-50 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 7.0E-50 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 7.0E-50 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 SUPERFAMILY SSF52096 11 191 1.46E-68 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 8.0E-99 T 01-11-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MLA2C4_14770 a005eddacb44023fd3466118d44577f8 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 01-11-2018 IPR033135 ClpP, histidine active site MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.6E-46 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.6E-46 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.6E-46 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.6E-46 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.6E-46 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.6E-46 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 7.9E-74 T 01-11-2018 MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 244 9.2E-91 T 01-11-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 Gene3D G3DSA:3.40.50.720 2 246 1.1E-90 T 01-11-2018 MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.4E-14 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.4E-14 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.4E-14 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0067 T 01-11-2018 MLA2C4_18455 16f8e985a826239b18e295431306f35d 246 SUPERFAMILY SSF51735 5 244 9.07E-89 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 Gene3D G3DSA:3.30.70.890 151 257 1.3E-79 T 01-11-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 SUPERFAMILY SSF55060 156 280 6.08E-32 T 01-11-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 Gene3D G3DSA:3.30.230.10 6 150 1.3E-79 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 Hamap MF_00384 Homoserine kinase [thrB]. 6 290 30.759 T 01-11-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 Pfam PF00288 GHMP kinases N terminal domain 75 135 2.0E-13 T 01-11-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 TIGRFAM TIGR00191 thrB: homoserine kinase 4 291 2.3E-77 T 01-11-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 PIRSF PIRSF000676 1 292 5.4E-92 T 01-11-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 Pfam PF08544 GHMP kinases C terminal 196 272 1.2E-11 T 01-11-2018 IPR013750 GHMP kinase, C-terminal domain MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 PRINTS PR00958 Homoserine kinase signature 88 103 7.7E-40 T 01-11-2018 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 PRINTS PR00958 Homoserine kinase signature 11 26 7.7E-40 T 01-11-2018 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 PRINTS PR00958 Homoserine kinase signature 122 135 7.7E-40 T 01-11-2018 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 PRINTS PR00958 Homoserine kinase signature 160 177 7.7E-40 T 01-11-2018 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 PRINTS PR00958 Homoserine kinase signature 240 255 7.7E-40 T 01-11-2018 MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 SUPERFAMILY SSF54211 5 147 2.2E-29 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_10020 ddd4d211106f14e749f1b25f781b8603 300 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 81 92 - T 01-11-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 183 8.6E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 8.6E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 132 8.6E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 212 8.6E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 8.6E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 268 8.6E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 54 284 9.2E-58 T 01-11-2018 MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 180 208 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 132 2.5E-8 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 193 212 2.5E-8 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 181 2.5E-8 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 SUPERFAMILY SSF51735 43 286 7.77E-79 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_04055 456a7aa0b8fa2db12da6cb182ee5cd11 288 Gene3D G3DSA:3.40.50.720 2 284 3.0E-85 T 01-11-2018 MLA2C4_26690 4c45df056ca1d1c9bff00d909119700f 168 Gene3D G3DSA:2.160.10.10 22 167 9.4E-28 T 01-11-2018 MLA2C4_26690 4c45df056ca1d1c9bff00d909119700f 168 SUPERFAMILY SSF51161 9 158 9.15E-33 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_26690 4c45df056ca1d1c9bff00d909119700f 168 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 107 140 1.9E-9 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 SUPERFAMILY SSF55486 309 354 8.29E-6 T 01-11-2018 MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 SUPERFAMILY SSF49785 507 650 7.8E-38 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 Gene3D G3DSA:2.60.120.260 495 651 7.6E-46 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 Pfam PF00754 F5/8 type C domain 526 646 1.7E-24 T 01-11-2018 IPR000421 Coagulation factor 5/8 C-terminal domain MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 PIRSF PIRSF036597 574 638 6.4E-6 T 01-11-2018 IPR012045 Peptidase M6, unassigned InhA-related MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 PIRSF PIRSF036597 538 580 0.0061 T 01-11-2018 IPR012045 Peptidase M6, unassigned InhA-related MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 PIRSF PIRSF036597 5 543 3.1E-185 T 01-11-2018 IPR012045 Peptidase M6, unassigned InhA-related MLA2C4_10870 e7992e9da9509836c88d8d1b10571784 653 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 151 431 1.0E-58 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_27850 5e58273930ecd1df54b97cc282598bd1 270 SUPERFAMILY SSF52540 4 231 1.11E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27850 5e58273930ecd1df54b97cc282598bd1 270 Pfam PF00005 ABC transporter 20 167 2.1E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_27850 5e58273930ecd1df54b97cc282598bd1 270 Gene3D G3DSA:3.40.50.300 3 255 4.6E-68 T 01-11-2018 MLA2C4_27850 5e58273930ecd1df54b97cc282598bd1 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_27850 5e58273930ecd1df54b97cc282598bd1 270 SMART SM00382 28 217 1.2E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_18335 5cf3ec3e340478817401049b65cb2e4a 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 255 1.5E-53 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_18335 5cf3ec3e340478817401049b65cb2e4a 263 Gene3D G3DSA:3.40.190.10 39 253 5.3E-62 T 01-11-2018 MLA2C4_18335 5cf3ec3e340478817401049b65cb2e4a 263 SMART SM00062 35 257 2.6E-59 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_18335 5cf3ec3e340478817401049b65cb2e4a 263 Gene3D G3DSA:3.40.190.10 117 220 5.3E-62 T 01-11-2018 MLA2C4_18335 5cf3ec3e340478817401049b65cb2e4a 263 SUPERFAMILY SSF53850 1 257 1.41E-59 T 01-11-2018 MLA2C4_18335 5cf3ec3e340478817401049b65cb2e4a 263 SMART SM00079 35 256 0.0023 T 01-11-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 Pfam PF01207 Dihydrouridine synthase (Dus) 14 319 1.5E-110 T 01-11-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 322 4.7E-134 T 01-11-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 01-11-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 Gene3D G3DSA:1.10.1200.80 254 331 5.1E-19 T 01-11-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 SUPERFAMILY SSF51395 11 322 1.19E-89 T 01-11-2018 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 Gene3D G3DSA:3.20.20.70 7 250 1.2E-80 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_00425 8606a2e9924e0ef09e259882fb2c2457 332 PIRSF PIRSF006621 1 330 4.2E-106 T 01-11-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MLA2C4_26110 45afdb0b55faade3c2a17d9c998b768c 701 Pfam PF00589 Phage integrase family 364 542 2.5E-26 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_26110 45afdb0b55faade3c2a17d9c998b768c 701 SUPERFAMILY SSF56349 356 551 1.56E-34 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_26110 45afdb0b55faade3c2a17d9c998b768c 701 Gene3D G3DSA:1.10.443.10 357 554 6.0E-33 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 SMART SM00838 400 488 9.8E-5 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 SUPERFAMILY SSF52540 3 211 3.56E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 PRINTS PR00315 GTP-binding elongation factor signature 54 62 2.6E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.6E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.6E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 PRINTS PR00315 GTP-binding elongation factor signature 10 23 2.6E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.6E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Gene3D G3DSA:3.30.70.870 311 595 2.8E-128 T 01-11-2018 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Gene3D G3DSA:3.40.50.300 5 203 1.3E-66 T 01-11-2018 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 604 3.3E-290 T 01-11-2018 IPR006298 GTP-binding protein TypA GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Pfam PF03144 Elongation factor Tu domain 2 224 294 2.1E-12 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Pfam PF00679 Elongation factor G C-terminus 402 482 2.5E-25 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 SUPERFAMILY SSF50447 155 304 1.5E-31 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 3.4E-57 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Pfam PF14492 Elongation Factor G, domain II 333 382 3.8E-7 T 01-11-2018 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 155 1.3E-22 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Gene3D G3DSA:3.30.70.240 394 487 2.8E-128 T 01-11-2018 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Gene3D G3DSA:2.40.30.10 204 304 1.5E-33 T 01-11-2018 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 SUPERFAMILY SSF54980 307 392 4.32E-15 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 Gene3D G3DSA:2.40.50.250 488 604 2.8E-128 T 01-11-2018 MLA2C4_20665 0ce8bd8bd61f680c9d0b06b5057f90b2 614 SUPERFAMILY SSF54980 403 518 3.36E-29 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_27840 12268951df19ca2514339a90faaf4835 434 SMART SM00471 57 187 1.4E-10 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_27840 12268951df19ca2514339a90faaf4835 434 Pfam PF01966 HD domain 61 180 4.2E-16 T 01-11-2018 IPR006674 HD domain MLA2C4_27840 12268951df19ca2514339a90faaf4835 434 Gene3D G3DSA:1.20.1250.30 235 412 9.9E-166 T 01-11-2018 MLA2C4_27840 12268951df19ca2514339a90faaf4835 434 Gene3D G3DSA:1.10.3210.10 12 401 9.9E-166 T 01-11-2018 MLA2C4_27840 12268951df19ca2514339a90faaf4835 434 SUPERFAMILY SSF109604 3 413 2.05E-119 T 01-11-2018 MLA2C4_27675 006e474577c44ffa5c42737bf2c55286 703 SUPERFAMILY SSF103501 7 238 3.53E-15 T 01-11-2018 IPR036197 NarG-like superfamily MLA2C4_27675 006e474577c44ffa5c42737bf2c55286 703 SUPERFAMILY SSF46548 252 400 1.46E-20 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_27675 006e474577c44ffa5c42737bf2c55286 703 Pfam PF13183 4Fe-4S dicluster domain 274 384 2.6E-12 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_27675 006e474577c44ffa5c42737bf2c55286 703 Pfam PF02754 Cysteine-rich domain 460 543 1.0E-6 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_27675 006e474577c44ffa5c42737bf2c55286 703 Pfam PF02754 Cysteine-rich domain 582 669 1.3E-17 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_27675 006e474577c44ffa5c42737bf2c55286 703 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 372 383 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:1.20.1640.10 528 1026 4.9E-275 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:3.30.70.1430 581 674 4.9E-275 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Pfam PF00873 AcrB/AcrD/AcrF family 4 244 1.0E-43 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Pfam PF00873 AcrB/AcrD/AcrF family 278 1029 6.0E-172 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 SUPERFAMILY SSF82714 726 810 3.92E-8 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:3.30.2090.10 177 293 4.9E-275 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:3.30.70.1320 132 349 4.9E-275 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:1.20.1640.10 11 527 4.9E-275 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 489 512 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 353 376 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 380 401 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 PRINTS PR00702 Acriflavin resistance protein family signature 566 583 1.6E-48 T 01-11-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 SUPERFAMILY SSF82693 134 345 7.72E-17 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:3.30.2090.10 724 812 4.9E-275 T 01-11-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:3.30.70.1430 41 820 4.9E-275 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 SUPERFAMILY SSF82866 314 515 1.57E-43 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 SUPERFAMILY SSF82866 811 1035 5.75E-47 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 Gene3D G3DSA:3.30.70.1440 675 869 4.9E-275 T 01-11-2018 MLA2C4_28155 680f80dfacae642aba488899a54bab91 1038 SUPERFAMILY SSF82693 41 133 1.96E-21 T 01-11-2018 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 Gene3D G3DSA:3.40.50.1970 2 172 1.4E-58 T 01-11-2018 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 349 1.2E-110 T 01-11-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 Gene3D G3DSA:1.20.1090.10 173 358 1.7E-52 T 01-11-2018 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 359 64.711 T 01-11-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 Pfam PF01761 3-dehydroquinate synthase 68 323 5.3E-96 T 01-11-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 PIRSF PIRSF001455 3 361 1.8E-101 T 01-11-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MLA2C4_07980 e3f4d69b4d72007f569784adc653f9be 361 SUPERFAMILY SSF56796 7 356 5.5E-98 T 01-11-2018 MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 Gene3D G3DSA:3.40.1190.20 1 302 6.9E-113 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 PIRSF PIRSF000535 1 303 1.4E-93 T 01-11-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 1.0E-112 T 01-11-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 SUPERFAMILY SSF53613 1 282 6.24E-71 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 Pfam PF00294 pfkB family carbohydrate kinase 7 280 1.2E-53 T 01-11-2018 IPR011611 Carbohydrate kinase PfkB MLA2C4_19415 1d4cd8bfb87f25937628c40c958f0562 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 2.1E-115 T 01-11-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MLA2C4_03455 aa0aa489e2fe1137f3c250ea3376323e 140 SUPERFAMILY SSF52402 1 140 1.0E-30 T 01-11-2018 MLA2C4_03455 aa0aa489e2fe1137f3c250ea3376323e 140 PRINTS PR01438 Universal stress protein signature 2 20 2.8E-19 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_03455 aa0aa489e2fe1137f3c250ea3376323e 140 PRINTS PR01438 Universal stress protein signature 100 112 2.8E-19 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_03455 aa0aa489e2fe1137f3c250ea3376323e 140 PRINTS PR01438 Universal stress protein signature 118 140 2.8E-19 T 01-11-2018 IPR006015 Universal stress protein A MLA2C4_03455 aa0aa489e2fe1137f3c250ea3376323e 140 Pfam PF00582 Universal stress protein family 1 140 1.8E-28 T 01-11-2018 IPR006016 UspA MLA2C4_03455 aa0aa489e2fe1137f3c250ea3376323e 140 Gene3D G3DSA:3.40.50.620 1 140 1.7E-34 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_26765 96c8189a301b57a6ca6afca46c077500 65 SMART SM00530 6 61 1.0E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_26765 96c8189a301b57a6ca6afca46c077500 65 Gene3D G3DSA:1.10.260.40 3 65 4.5E-27 T 01-11-2018 MLA2C4_26765 96c8189a301b57a6ca6afca46c077500 65 Pfam PF01381 Helix-turn-helix 7 61 9.8E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_26765 96c8189a301b57a6ca6afca46c077500 65 SUPERFAMILY SSF47413 3 63 1.66E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 491 3.2E-85 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 SUPERFAMILY SSF53850 64 560 6.6E-124 T 01-11-2018 MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 PIRSF PIRSF002741 12 568 1.9E-115 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 Gene3D G3DSA:3.10.105.10 325 542 6.8E-128 T 01-11-2018 MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 115 137 - T 01-11-2018 IPR023765 Solute-binding protein family 5, conserved site MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 Gene3D G3DSA:3.40.190.10 80 556 6.8E-128 T 01-11-2018 MLA2C4_01295 fdecea998c0087b609a21f8d8ae932fd 575 Gene3D G3DSA:3.90.76.10 98 229 6.8E-128 T 01-11-2018 MLA2C4_06775 3b6ec6c5dc16c117cea3e5116d522a50 989 Pfam PF04851 Type III restriction enzyme, res subunit 9 246 1.0E-17 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MLA2C4_06775 3b6ec6c5dc16c117cea3e5116d522a50 989 SUPERFAMILY SSF52540 87 280 7.42E-14 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06775 3b6ec6c5dc16c117cea3e5116d522a50 989 SUPERFAMILY SSF52540 88 557 3.36E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06775 3b6ec6c5dc16c117cea3e5116d522a50 989 Gene3D G3DSA:3.40.50.300 74 257 4.3E-13 T 01-11-2018 MLA2C4_12590 871d4a4f9bd8527d49f661085b2f3548 125 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 6 124 5.1E-16 T 01-11-2018 IPR006524 Transcription activator, ArpU family MLA2C4_19615 16130183db6fc641bc42875de7e911f6 141 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 131 6.8E-62 T 01-11-2018 IPR019723 Uncharacterised protein, YfmQ MLA2C4_01175 a3c2719227043b436ab1d85a5747f241 322 Pfam PF00892 EamA-like transporter family 8 146 7.1E-20 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_01175 a3c2719227043b436ab1d85a5747f241 322 Pfam PF00892 EamA-like transporter family 163 296 5.0E-7 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 Gene3D G3DSA:3.20.20.80 1 469 2.4E-174 T 01-11-2018 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 01-11-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 Pfam PF00232 Glycosyl hydrolase family 1 2 466 8.7E-169 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 01-11-2018 IPR018120 Glycoside hydrolase family 1, active site MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 SUPERFAMILY SSF51445 1 467 3.77E-168 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 6.7E-18 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 6.7E-18 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 6.7E-18 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 6.7E-18 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_19645 9bdb4e44c1630908234dab77c45a8e1e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 6.7E-18 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_16440 c5c40e8b2180ae67c40ff8fc3eb35906 314 SMART SM00448 1 114 4.2E-20 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_16440 c5c40e8b2180ae67c40ff8fc3eb35906 314 Pfam PF00072 Response regulator receiver domain 4 114 2.1E-20 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_16440 c5c40e8b2180ae67c40ff8fc3eb35906 314 Gene3D G3DSA:3.40.50.2300 2 131 1.5E-22 T 01-11-2018 MLA2C4_16440 c5c40e8b2180ae67c40ff8fc3eb35906 314 Pfam PF08664 YcbB domain 166 302 2.2E-49 T 01-11-2018 IPR013972 YcbB domain MLA2C4_16440 c5c40e8b2180ae67c40ff8fc3eb35906 314 SUPERFAMILY SSF52172 5 135 6.97E-24 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_16770 86762251b29e09085a67d10739a3cf70 145 SUPERFAMILY SSF54593 1 120 5.37E-24 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_16770 86762251b29e09085a67d10739a3cf70 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 2.8E-17 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_16770 86762251b29e09085a67d10739a3cf70 145 Gene3D G3DSA:3.10.180.10 1 123 2.4E-49 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 6 302 2.2E-90 T 01-11-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 Pfam PF11858 Domain of unknown function (DUF3378) 5 78 1.4E-26 T 01-11-2018 IPR024568 Ribonuclease HIII, N-terminal MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 Gene3D G3DSA:3.30.420.10 95 312 3.3E-81 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 Pfam PF01351 Ribonuclease HII 98 302 6.6E-48 T 01-11-2018 IPR024567 Ribonuclease HII/HIII domain MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 PIRSF PIRSF037748 1 311 1.3E-121 T 01-11-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 SUPERFAMILY SSF53098 96 310 5.92E-53 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 Gene3D G3DSA:3.30.310.10 1 87 2.6E-28 T 01-11-2018 IPR012295 TBP domain superfamily MLA2C4_23670 e2049ea1a6e8ce8a43676be9416c013b 312 Hamap MF_00053 Ribonuclease HIII [rnhC]. 2 310 36.935 T 01-11-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.1E-11 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.1E-11 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.1E-11 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 SUPERFAMILY SSF46894 144 212 1.6E-18 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 SMART SM00448 3 116 1.2E-36 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 4.2E-19 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 Pfam PF00072 Response regulator receiver domain 5 116 5.0E-33 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 SMART SM00421 149 206 9.5E-20 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 SUPERFAMILY SSF52172 1 135 4.41E-38 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_05385 8524d309d7aa024c74a07b2fba896230 214 Gene3D G3DSA:3.40.50.12740 4 212 1.0E-66 T 01-11-2018 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 Pfam PF04055 Radical SAM superfamily 28 123 2.2E-11 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 235 36.167 T 01-11-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 PIRSF PIRSF000370 2 238 2.0E-52 T 01-11-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 Pfam PF13353 4Fe-4S single cluster domain 14 117 6.2E-10 T 01-11-2018 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 SUPERFAMILY SSF102114 26 163 2.22E-13 T 01-11-2018 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 Gene3D G3DSA:3.20.20.70 4 214 4.4E-31 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_07120 8bf552c97a0600cb2bd93bcf7c24135d 238 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 238 4.4E-121 T 01-11-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 Gene3D G3DSA:1.10.10.10 130 225 1.8E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 Pfam PF00072 Response regulator receiver domain 5 113 5.5E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 SUPERFAMILY SSF52172 3 182 2.78E-41 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 Gene3D G3DSA:3.40.50.2300 1 127 1.8E-38 T 01-11-2018 MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 SMART SM00448 3 113 7.9E-45 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 SMART SM00862 150 223 6.5E-27 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_18700 5b0e4ce7ef2a1cff0b114548d8d46a6c 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 7.2E-26 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09350 6a467b47a4ad06034306cdbd0da7ec44 403 Gene3D G3DSA:1.20.1250.20 14 199 3.4E-20 T 01-11-2018 MLA2C4_09350 6a467b47a4ad06034306cdbd0da7ec44 403 SUPERFAMILY SSF103473 12 395 9.81E-57 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_09350 6a467b47a4ad06034306cdbd0da7ec44 403 Gene3D G3DSA:1.20.1250.20 221 401 1.7E-25 T 01-11-2018 MLA2C4_09350 6a467b47a4ad06034306cdbd0da7ec44 403 Pfam PF07690 Major Facilitator Superfamily 23 361 1.7E-32 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 Gene3D G3DSA:3.20.20.110 122 414 2.3E-99 T 01-11-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 101 9.8E-5 T 01-11-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 SUPERFAMILY SSF54966 2 121 1.57E-29 T 01-11-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 SUPERFAMILY SSF51649 121 409 8.77E-77 T 01-11-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 406 61.997 T 01-11-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 127 403 2.5E-33 T 01-11-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 Gene3D G3DSA:3.30.70.150 1 121 4.9E-31 T 01-11-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 MLA2C4_21110 e64a861e27b4bd8aba95712919687163 414 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 406 6.6E-236 T 01-11-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 MLA2C4_23515 87de006fa3d3daa0865c7661dd17002d 257 SMART SM00893 21 211 9.6E-55 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MLA2C4_23515 87de006fa3d3daa0865c7661dd17002d 257 Pfam PF01012 Electron transfer flavoprotein domain 28 206 3.3E-48 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MLA2C4_23515 87de006fa3d3daa0865c7661dd17002d 257 Gene3D G3DSA:3.40.50.620 1 256 6.8E-83 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_23515 87de006fa3d3daa0865c7661dd17002d 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 01-11-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MLA2C4_23515 87de006fa3d3daa0865c7661dd17002d 257 PIRSF PIRSF000090 1 257 1.2E-75 T 01-11-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MLA2C4_23515 87de006fa3d3daa0865c7661dd17002d 257 SUPERFAMILY SSF52402 1 246 6.51E-75 T 01-11-2018 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 SUPERFAMILY SSF69055 288 379 6.28E-32 T 01-11-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 6.1E-171 T 01-11-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 128 1.4E-41 T 01-11-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 Pfam PF13288 DXP reductoisomerase C-terminal domain 257 374 4.1E-44 T 01-11-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 PIRSF PIRSF006205 1 380 7.6E-162 T 01-11-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 Gene3D G3DSA:3.40.50.720 1 146 6.7E-49 T 01-11-2018 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 SUPERFAMILY SSF51735 2 146 2.35E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 47.33 T 01-11-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 142 225 2.7E-42 T 01-11-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 Gene3D G3DSA:1.10.1740.10 299 380 6.7E-30 T 01-11-2018 MLA2C4_19975 41066531cb0e6e5b70b73fe7bea19d26 380 SUPERFAMILY SSF55347 122 260 9.81E-62 T 01-11-2018 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 Gene3D G3DSA:3.50.50.60 34 379 8.3E-45 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 457 468 4.2E-8 T 01-11-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 490 502 4.2E-8 T 01-11-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 478 490 4.2E-8 T 01-11-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 SUPERFAMILY SSF51905 30 385 1.49E-32 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 Gene3D G3DSA:2.102.10.10 406 508 1.5E-25 T 01-11-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 Pfam PF01266 FAD dependent oxidoreductase 33 376 1.4E-42 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 Pfam PF00355 Rieske [2Fe-2S] domain 423 504 3.6E-14 T 01-11-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 Gene3D G3DSA:3.30.9.10 126 337 8.3E-45 T 01-11-2018 MLA2C4_02145 10c2dd7f41dd41425f7a7040af61e1e0 508 SUPERFAMILY SSF50022 423 505 8.38E-25 T 01-11-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 SUPERFAMILY SSF54534 126 221 2.75E-33 T 01-11-2018 MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 Gene3D G3DSA:3.10.50.40 128 221 9.0E-39 T 01-11-2018 MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 Hamap MF_01145 Foldase protein PrsA [prsA]. 1 279 23.729 T 01-11-2018 IPR023059 Foldase protein PrsA GO:0003755 MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 SUPERFAMILY SSF109998 35 161 1.1E-19 T 01-11-2018 IPR027304 Trigger factor/SurA domain superfamily MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 Gene3D G3DSA:1.10.3120.10 20 127 9.3E-8 T 01-11-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 160 181 - T 01-11-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MLA2C4_05555 1d792dcc451402c9b86c9c96bf2b2054 288 Pfam PF13616 PPIC-type PPIASE domain 130 222 4.0E-28 T 01-11-2018 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 922 0.0 T 01-11-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Gene3D G3DSA:3.30.190.20 132 241 4.7E-256 T 01-11-2018 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Gene3D G3DSA:1.20.1580.10 691 828 1.0E-145 T 01-11-2018 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Gene3D G3DSA:1.10.8.280 286 403 4.7E-256 T 01-11-2018 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 SUPERFAMILY SSF52540 617 907 9.51E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Gene3D G3DSA:3.40.50.300 7 595 4.7E-256 T 01-11-2018 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Gene3D G3DSA:3.40.50.300 613 934 1.0E-145 T 01-11-2018 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.485 T 01-11-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Pfam PF00005 ABC transporter 622 858 4.0E-10 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 SUPERFAMILY SSF52540 13 569 2.16E-47 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26720 2705776c1e97e4ecc22b4f223ef740b5 956 Gene3D G3DSA:1.20.1580.10 92 492 4.7E-256 T 01-11-2018 MLA2C4_20020 b44bbf6df251141f6479d609f61183d6 180 PIRSF PIRSF039093 1 180 4.2E-85 T 01-11-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MLA2C4_20020 b44bbf6df251141f6479d609f61183d6 180 Gene3D G3DSA:3.60.20.10 2 180 2.3E-69 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_20020 b44bbf6df251141f6479d609f61183d6 180 Pfam PF00227 Proteasome subunit 5 178 3.7E-25 T 01-11-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 MLA2C4_20020 b44bbf6df251141f6479d609f61183d6 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.124 T 01-11-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MLA2C4_20020 b44bbf6df251141f6479d609f61183d6 180 SUPERFAMILY SSF56235 4 179 3.66E-59 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_20020 b44bbf6df251141f6479d609f61183d6 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 1.2E-84 T 01-11-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MLA2C4_25960 3999ae84873fe13d56eddc2dcd69ff43 114 SUPERFAMILY SSF110455 1 111 6.54E-34 T 01-11-2018 MLA2C4_25960 3999ae84873fe13d56eddc2dcd69ff43 114 SMART SM00493 5 79 4.0E-7 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_25960 3999ae84873fe13d56eddc2dcd69ff43 114 Gene3D G3DSA:3.40.1360.20 1 114 8.8E-43 T 01-11-2018 MLA2C4_25960 3999ae84873fe13d56eddc2dcd69ff43 114 Pfam PF01751 Toprim domain 7 75 9.1E-5 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 Gene3D G3DSA:1.10.10.10 215 309 2.3E-37 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 6.5E-37 T 01-11-2018 IPR039518 WhiA, LAGLIDADG-like domain MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 1.1E-136 T 01-11-2018 IPR033981 Sporulation regulator WhiA-like MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.804 T 01-11-2018 IPR003802 Sporulation regulator WhiA GO:0043937 MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 Gene3D G3DSA:3.10.28.10 1 214 1.6E-67 T 01-11-2018 IPR027434 Homing endonuclease MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.5E-35 T 01-11-2018 IPR023054 Sporulation regulator WhiA, C-terminal MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 SUPERFAMILY SSF55608 120 221 7.94E-20 T 01-11-2018 IPR027434 Homing endonuclease MLA2C4_26655 ee4098b04dc6835db53c267625517849 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 103 4.0E-37 T 01-11-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 Gene3D G3DSA:3.40.1280.10 71 249 1.7E-65 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 SUPERFAMILY SSF88697 1 67 1.34E-11 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 PIRSF PIRSF015601 1 248 4.0E-63 T 01-11-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 248 4.0E-70 T 01-11-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 Pfam PF04452 RNA methyltransferase 17 243 9.2E-73 T 01-11-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 SUPERFAMILY SSF75217 72 248 2.09E-56 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases MLA2C4_22515 59c47bb44ab8d95ebdf72481ef6c13ff 249 Gene3D G3DSA:2.40.240.20 1 69 2.9E-18 T 01-11-2018 MLA2C4_19175 917fc31c21223fdfcc0cd77d94d2cbf7 264 Gene3D G3DSA:1.10.3720.10 64 264 9.2E-32 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_19175 917fc31c21223fdfcc0cd77d94d2cbf7 264 SUPERFAMILY SSF161098 70 255 2.35E-33 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_19175 917fc31c21223fdfcc0cd77d94d2cbf7 264 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 17 264 3.6E-91 T 01-11-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 MLA2C4_19175 917fc31c21223fdfcc0cd77d94d2cbf7 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 260 5.1E-16 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 TIGRFAM TIGR00115 tig: trigger factor 14 421 7.4E-144 T 01-11-2018 IPR005215 Trigger factor GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 9.3E-43 T 01-11-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Gene3D G3DSA:3.10.50.40 151 248 5.4E-98 T 01-11-2018 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Gene3D G3DSA:1.10.3120.10 115 424 5.4E-98 T 01-11-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Hamap MF_00303 Trigger factor [tig]. 1 425 23.827 T 01-11-2018 IPR005215 Trigger factor GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 3.4E-49 T 01-11-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 PIRSF PIRSF003095 1 425 2.6E-139 T 01-11-2018 IPR005215 Trigger factor GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 SUPERFAMILY SSF54534 89 243 2.36E-37 T 01-11-2018 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 SUPERFAMILY SSF102735 1 128 4.32E-37 T 01-11-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 SUPERFAMILY SSF109998 250 424 1.57E-45 T 01-11-2018 IPR027304 Trigger factor/SurA domain superfamily MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 238 8.1E-14 T 01-11-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MLA2C4_23315 9a1097285751b0c584ccb0865c528c85 425 Gene3D G3DSA:3.30.70.1050 3 114 1.7E-28 T 01-11-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 SUPERFAMILY SSF52777 171 399 4.0E-80 T 01-11-2018 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 Gene3D G3DSA:4.10.320.10 112 161 1.7E-15 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 SUPERFAMILY SSF47005 116 158 1.24E-9 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 Pfam PF02817 e3 binding domain 119 154 9.8E-14 T 01-11-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 Gene3D G3DSA:3.30.559.10 162 397 1.6E-85 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 Pfam PF00364 Biotin-requiring enzyme 4 76 6.5E-17 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 Gene3D G3DSA:2.40.50.100 2 97 4.1E-23 T 01-11-2018 MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 SUPERFAMILY SSF51230 1 85 6.94E-22 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_14690 a7a47e4393def00b5e6e9ae3c466cc9f 399 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 170 398 8.7E-83 T 01-11-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 01-11-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 SUPERFAMILY SSF52833 1 158 5.61E-64 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 Pfam PF00255 Glutathione peroxidase 3 109 3.1E-44 T 01-11-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 PIRSF PIRSF000303 1 160 3.7E-68 T 01-11-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 Gene3D G3DSA:3.40.30.10 1 160 8.5E-73 T 01-11-2018 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 01-11-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.1E-21 T 01-11-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.1E-21 T 01-11-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MLA2C4_10790 94cae958dcd429b1affb46b2a009630d 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.1E-21 T 01-11-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 4.2E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 SMART SM00862 148 223 2.5E-20 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 SUPERFAMILY SSF52172 3 131 1.24E-26 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 Gene3D G3DSA:1.10.10.10 123 225 1.0E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 SMART SM00448 2 112 4.2E-20 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 SUPERFAMILY SSF46894 124 224 9.92E-28 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 Pfam PF00072 Response regulator receiver domain 4 112 5.0E-18 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_26505 0db966c76edf01bf5b560f558beb0c48 225 Gene3D G3DSA:3.40.50.2300 1 121 3.8E-27 T 01-11-2018 MLA2C4_21970 0891b82e3e6b3ed89a927bedc695ecb1 162 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 3 142 1.0E-73 T 01-11-2018 IPR024563 Uncharacterised protein family YqhR MLA2C4_21970 0891b82e3e6b3ed89a927bedc695ecb1 162 Pfam PF11085 Conserved membrane protein YqhR 10 151 3.2E-43 T 01-11-2018 IPR024563 Uncharacterised protein family YqhR MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 561 607 3.5E-9 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 402 446 9.5E-5 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 552 664 1.1E-9 T 01-11-2018 IPR026466 Fimbrial isopeptide formation D2 domain MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 689 802 4.3E-11 T 01-11-2018 IPR026466 Fimbrial isopeptide formation D2 domain MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 826 962 7.0E-13 T 01-11-2018 IPR026466 Fimbrial isopeptide formation D2 domain MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 390 515 5.6E-14 T 01-11-2018 IPR026466 Fimbrial isopeptide formation D2 domain MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 SUPERFAMILY SSF49401 568 671 1.37E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 Gene3D G3DSA:2.60.40.10 981 1078 1.2E-21 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 SUPERFAMILY SSF49401 703 811 3.48E-7 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1074 1105 4.4E-5 T 01-11-2018 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 SUPERFAMILY SSF49478 987 1054 2.16E-8 T 01-11-2018 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 Gene3D G3DSA:2.60.40.740 832 977 1.1E-17 T 01-11-2018 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 Gene3D G3DSA:2.60.40.740 391 537 3.4E-8 T 01-11-2018 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 Pfam PF01345 Domain of unknown function DUF11 555 659 8.1E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 Gene3D G3DSA:2.60.40.740 549 688 2.4E-11 T 01-11-2018 MLA2C4_08795 5b805c88abffdbb8a64225a3a08cd42d 1108 Gene3D G3DSA:2.60.40.740 689 831 3.0E-10 T 01-11-2018 MLA2C4_27985 65a4b9767b669a209abff8cd2dc8cec2 293 Gene3D G3DSA:3.40.50.1110 50 279 5.2E-35 T 01-11-2018 IPR036514 SGNH hydrolase superfamily MLA2C4_27985 65a4b9767b669a209abff8cd2dc8cec2 293 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 85 270 1.9E-22 T 01-11-2018 IPR013830 SGNH hydrolase-type esterase domain MLA2C4_27985 65a4b9767b669a209abff8cd2dc8cec2 293 SUPERFAMILY SSF52266 79 282 1.06E-36 T 01-11-2018 MLA2C4_22720 a85d6504308e07a2bcd2015beb722768 40 Pfam PF13215 Protein of unknown function (DUF4023) 1 38 1.2E-19 T 01-11-2018 IPR025097 Protein of unknown function DUF4023 MLA2C4_08645 22c4d503da686ac20dbde12d219c0a76 409 Pfam PF07559 Flagellar basal body protein FlaE 187 288 5.4E-6 T 01-11-2018 IPR011491 Flagellar hook protein FlgE MLA2C4_08645 22c4d503da686ac20dbde12d219c0a76 409 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 330 407 9.8E-16 T 01-11-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MLA2C4_08645 22c4d503da686ac20dbde12d219c0a76 409 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 390 1.7E-66 T 01-11-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G MLA2C4_08645 22c4d503da686ac20dbde12d219c0a76 409 SUPERFAMILY SSF117143 94 367 5.23E-52 T 01-11-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like MLA2C4_08645 22c4d503da686ac20dbde12d219c0a76 409 Pfam PF00460 Flagella basal body rod protein 5 35 4.3E-10 T 01-11-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MLA2C4_08645 22c4d503da686ac20dbde12d219c0a76 409 Gene3D G3DSA:2.60.98.20 181 290 1.3E-5 T 01-11-2018 IPR037058 Flagellar hook protein FlgE superfamily MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 Gene3D G3DSA:1.10.10.10 6 142 2.4E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 Pfam PF01047 MarR family 33 89 1.7E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 SMART SM00347 25 125 1.2E-25 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 2.3E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 2.3E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 2.3E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 2.3E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15945 4ee3e3118909054c384672abdd2e53f9 142 SUPERFAMILY SSF46785 21 140 5.12E-27 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08505 23619d91dacdd81489f0aa935b22ddd3 62 Pfam PF17209 Hfq protein 4 61 2.4E-18 T 01-11-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MLA2C4_08505 23619d91dacdd81489f0aa935b22ddd3 62 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 62 24.867 T 01-11-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MLA2C4_08505 23619d91dacdd81489f0aa935b22ddd3 62 Gene3D G3DSA:2.30.30.100 1 62 2.8E-20 T 01-11-2018 MLA2C4_08505 23619d91dacdd81489f0aa935b22ddd3 62 SUPERFAMILY SSF50182 3 61 3.74E-18 T 01-11-2018 IPR010920 LSM domain superfamily MLA2C4_08505 23619d91dacdd81489f0aa935b22ddd3 62 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 3 61 9.3E-21 T 01-11-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MLA2C4_16225 751c7386c68727d09e5e2b0ce170c2a4 403 SUPERFAMILY SSF53383 8 392 2.37E-110 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_16225 751c7386c68727d09e5e2b0ce170c2a4 403 Pfam PF00155 Aminotransferase class I and II 44 381 1.0E-62 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_16225 751c7386c68727d09e5e2b0ce170c2a4 403 Gene3D G3DSA:3.40.640.10 57 291 3.4E-147 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_16225 751c7386c68727d09e5e2b0ce170c2a4 403 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 01-11-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MLA2C4_16225 751c7386c68727d09e5e2b0ce170c2a4 403 Gene3D G3DSA:3.90.1150.10 37 384 3.4E-147 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 ProSitePatterns PS00760 Signal peptidases I lysine active site. 77 89 - T 01-11-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 Pfam PF00717 Peptidase S24-like 30 99 9.5E-19 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 166 3.5E-50 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 2.8E-17 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 87 2.8E-17 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 125 144 2.8E-17 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 Gene3D G3DSA:2.10.109.10 54 172 8.1E-35 T 01-11-2018 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 ProSitePatterns PS00761 Signal peptidases I signature 3. 130 143 - T 01-11-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 SUPERFAMILY SSF51306 25 172 6.63E-48 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_16140 dcc3b4deb0575ab818ccd66245294240 173 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 01-11-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 01-11-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 SMART SM01192 139 428 8.5E-227 T 01-11-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 Hamap MF_00318 Enolase [eno]. 2 414 46.348 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PRINTS PR00148 Enolase signature 366 383 1.5E-46 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PRINTS PR00148 Enolase signature 107 123 1.5E-46 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PRINTS PR00148 Enolase signature 314 325 1.5E-46 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PRINTS PR00148 Enolase signature 337 351 1.5E-46 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PRINTS PR00148 Enolase signature 37 51 1.5E-46 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PRINTS PR00148 Enolase signature 161 174 1.5E-46 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 SUPERFAMILY SSF51604 138 428 2.4E-133 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 PIRSF PIRSF001400 1 428 5.0E-198 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 Gene3D G3DSA:3.20.20.120 128 431 2.5E-139 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 Gene3D G3DSA:3.30.390.10 1 127 4.0E-60 T 01-11-2018 IPR029017 Enolase-like, N-terminal MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 1.2E-218 T 01-11-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 3.4E-142 T 01-11-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 SUPERFAMILY SSF54826 3 138 2.36E-61 T 01-11-2018 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 SMART SM01193 4 134 6.2E-103 T 01-11-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26565 be33188b4a85b192dfb152c5b695bebe 431 Pfam PF03952 Enolase, N-terminal domain 4 134 6.4E-63 T 01-11-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 SUPERFAMILY SSF51735 3 179 5.1E-60 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 Gene3D G3DSA:1.10.1040.10 190 336 4.2E-54 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.241 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 3.9E-57 T 01-11-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PIRSF PIRSF000114 1 333 8.9E-110 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 1.3E-55 T 01-11-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.4E-47 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 1.4E-47 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 1.4E-47 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 1.4E-47 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 1.4E-47 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 1.4E-47 T 01-11-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 SUPERFAMILY SSF48179 181 332 9.52E-59 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_07920 50a56f696d14ce67a0d09332000cda37 340 Gene3D G3DSA:3.40.50.720 1 188 2.9E-66 T 01-11-2018 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 411 4.8E-52 T 01-11-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 01-11-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 Gene3D G3DSA:3.90.110.10 170 441 1.4E-107 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 SUPERFAMILY SSF51735 3 167 7.04E-58 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 1.3E-48 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 Pfam PF02056 Family 4 glycosyl hydrolase 5 186 1.0E-70 T 01-11-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 Gene3D G3DSA:3.40.50.720 2 169 3.6E-73 T 01-11-2018 MLA2C4_26935 eb45e8f0027014cc73fa02a3f0327071 441 SUPERFAMILY SSF56327 172 438 7.56E-101 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Pfam PF13185 GAF domain 275 410 2.1E-10 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 563 5.1E-18 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Pfam PF05227 CHASE3 domain 46 172 2.8E-18 T 01-11-2018 IPR007891 CHASE3 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Gene3D G3DSA:3.30.450.40 246 412 6.2E-13 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SUPERFAMILY SSF55781 255 439 2.59E-22 T 01-11-2018 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SUPERFAMILY SSF52172 773 893 4.13E-37 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 610 731 6.8E-29 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SMART SM00388 495 563 4.2E-22 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SUPERFAMILY SSF55874 552 734 3.27E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Pfam PF00072 Response regulator receiver domain 778 888 2.9E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Gene3D G3DSA:3.40.50.12740 775 894 5.1E-40 T 01-11-2018 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Gene3D G3DSA:1.10.287.130 460 561 1.2E-24 T 01-11-2018 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Gene3D G3DSA:1.20.1440.210 50 169 4.1E-10 T 01-11-2018 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 Gene3D G3DSA:3.30.565.10 562 733 1.1E-46 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 712 1.7E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 731 1.7E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 673 1.7E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 687 1.7E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SMART SM00448 776 890 4.7E-37 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SMART SM00387 610 734 7.5E-37 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05340 1033d5048471715f5b1a790befd2bf9e 896 SUPERFAMILY SSF47384 481 564 2.55E-21 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 SUPERFAMILY SSF51735 2 185 5.33E-65 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 Gene3D G3DSA:3.40.50.720 1 188 1.1E-74 T 01-11-2018 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 9.6E-69 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 SUPERFAMILY SSF48179 185 283 1.11E-33 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 Gene3D G3DSA:1.10.1040.10 193 278 8.3E-36 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 01-11-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 7.0E-36 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MLA2C4_27665 6898b1d82f103bd4401d3572d5f81b71 283 PIRSF PIRSF000105 1 283 1.2E-95 T 01-11-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 MLA2C4_21720 c566a08b7eea18d612ced1ee0d0b357c 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 1.0E-29 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MLA2C4_21720 c566a08b7eea18d612ced1ee0d0b357c 219 SUPERFAMILY SSF161098 13 201 1.57E-44 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_21720 c566a08b7eea18d612ced1ee0d0b357c 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 1.8E-19 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_21720 c566a08b7eea18d612ced1ee0d0b357c 219 Gene3D G3DSA:1.10.3720.10 1 219 3.8E-57 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 2.5E-36 T 01-11-2018 IPR013332 Ketopantoate reductase, N-terminal domain MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 Gene3D G3DSA:1.10.1040.10 177 301 3.8E-31 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 Gene3D G3DSA:3.40.50.720 1 171 6.3E-51 T 01-11-2018 MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 177 300 3.2E-26 T 01-11-2018 IPR013752 Ketopantoate reductase, C-terminal domain MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 302 3.4E-71 T 01-11-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 SUPERFAMILY SSF51735 1 129 1.58E-15 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_09585 bf4078b34f158c76b014ce7e06ab644b 314 SUPERFAMILY SSF48179 177 301 1.09E-28 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 Gene3D G3DSA:3.30.420.40 1 252 1.7E-115 T 01-11-2018 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 SUPERFAMILY SSF53067 3 254 2.51E-99 T 01-11-2018 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 Gene3D G3DSA:3.30.420.40 253 496 6.9E-90 T 01-11-2018 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 1.5E-63 T 01-11-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.977 T 01-11-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 9.4E-92 T 01-11-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 493 2.6E-229 T 01-11-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 SUPERFAMILY SSF53067 254 491 3.89E-86 T 01-11-2018 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 PIRSF PIRSF000538 2 496 2.7E-183 T 01-11-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_05510 210ee960611bf5bfe430bc05984bb129 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 Gene3D G3DSA:3.40.640.10 62 284 1.0E-142 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.3E-17 T 01-11-2018 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.3E-17 T 01-11-2018 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.3E-17 T 01-11-2018 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.3E-17 T 01-11-2018 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.3E-17 T 01-11-2018 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 Pfam PF00155 Aminotransferase class I and II 31 385 1.4E-82 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 Gene3D G3DSA:3.90.1150.10 25 385 1.0E-142 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_08125 f5fe717d028189df98d1397fcca80515 395 SUPERFAMILY SSF53383 1 390 6.65E-120 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22290 57c543fc805780a1f97a478c2999e418 66 SUPERFAMILY SSF158379 1 61 1.7E-22 T 01-11-2018 IPR023164 YqgQ-like superfamily MLA2C4_22290 57c543fc805780a1f97a478c2999e418 66 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 4.0E-27 T 01-11-2018 IPR009256 Protein of unknown function DUF910 MLA2C4_22290 57c543fc805780a1f97a478c2999e418 66 Gene3D G3DSA:1.10.287.760 1 66 2.6E-26 T 01-11-2018 IPR023164 YqgQ-like superfamily MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 SUPERFAMILY SSF53659 3 344 4.32E-115 T 01-11-2018 MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 Gene3D G3DSA:3.40.718.10 1 352 8.3E-136 T 01-11-2018 MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 343 1.0E-138 T 01-11-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 SMART SM01329 4 340 3.5E-178 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 344 45.633 T 01-11-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 340 1.9E-124 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MLA2C4_07410 e501c81abee8f69280a305aa2cf68eda 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 235 254 - T 01-11-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MLA2C4_27685 097b3f8508ab3b39704123f48aa9003a 317 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 303 41.147 T 01-11-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 MLA2C4_27685 097b3f8508ab3b39704123f48aa9003a 317 SUPERFAMILY SSF51658 83 254 6.75E-16 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily MLA2C4_27685 097b3f8508ab3b39704123f48aa9003a 317 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 302 5.3E-101 T 01-11-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 MLA2C4_27685 097b3f8508ab3b39704123f48aa9003a 317 Pfam PF03851 UV-endonuclease UvdE 5 273 2.4E-119 T 01-11-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 MLA2C4_27685 097b3f8508ab3b39704123f48aa9003a 317 Gene3D G3DSA:3.20.20.150 2 307 1.2E-94 T 01-11-2018 MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 SUPERFAMILY SSF141868 654 902 9.42E-84 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 SUPERFAMILY SSF55073 484 640 1.73E-44 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 SMART SM00267 467 639 1.1E-51 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 476 637 3.5E-36 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 Gene3D G3DSA:3.30.450.20 344 472 1.2E-19 T 01-11-2018 MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 Pfam PF08448 PAS fold 365 468 5.7E-10 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 Gene3D G3DSA:3.30.70.270 473 651 1.5E-52 T 01-11-2018 MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 SMART SM00052 649 895 1.4E-109 T 01-11-2018 IPR001633 EAL domain MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 SMART SM00091 355 421 9.4E-7 T 01-11-2018 IPR000014 PAS domain MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 SUPERFAMILY SSF55785 346 465 2.62E-17 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 352 474 5.0E-18 T 01-11-2018 IPR000014 PAS domain MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 Gene3D G3DSA:3.20.20.450 652 904 5.4E-94 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 Pfam PF00563 EAL domain 655 890 2.5E-69 T 01-11-2018 IPR001633 EAL domain MLA2C4_19580 fb290b041592bf998b9b19b6f3b8022a 906 Pfam PF00990 Diguanylate cyclase, GGDEF domain 478 633 3.3E-43 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_28405 df5b8106a4340f8ada98d55d8026b640 173 Gene3D G3DSA:2.40.50.140 1 110 3.6E-46 T 01-11-2018 MLA2C4_28405 df5b8106a4340f8ada98d55d8026b640 173 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.567 T 01-11-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_28405 df5b8106a4340f8ada98d55d8026b640 173 SUPERFAMILY SSF50249 2 173 5.14E-58 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_28405 df5b8106a4340f8ada98d55d8026b640 173 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 173 4.2E-49 T 01-11-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_28405 df5b8106a4340f8ada98d55d8026b640 173 Pfam PF00436 Single-strand binding protein family 2 103 7.2E-39 T 01-11-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MLA2C4_28405 df5b8106a4340f8ada98d55d8026b640 173 PIRSF PIRSF002070 1 160 6.2E-41 T 01-11-2018 MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 Gene3D G3DSA:3.30.1300.10 178 277 1.3E-31 T 01-11-2018 MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 70 5.8E-8 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 5.3E-111 T 01-11-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 38.805 T 01-11-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 Pfam PF02569 Pantoate-beta-alanine ligase 2 277 2.3E-100 T 01-11-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 Gene3D G3DSA:3.40.50.620 1 177 1.8E-74 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_08100 d1dc0e01abda93545ba12f8c8561bafb 282 SUPERFAMILY SSF52374 1 279 2.95E-105 T 01-11-2018 MLA2C4_24875 71574eb650f367a2d5f2529d61fd6267 335 Gene3D G3DSA:3.40.190.10 28 129 6.6E-16 T 01-11-2018 MLA2C4_24875 71574eb650f367a2d5f2529d61fd6267 335 Pfam PF13379 NMT1-like family 31 264 6.0E-27 T 01-11-2018 MLA2C4_24875 71574eb650f367a2d5f2529d61fd6267 335 SUPERFAMILY SSF53850 32 260 9.06E-34 T 01-11-2018 MLA2C4_24875 71574eb650f367a2d5f2529d61fd6267 335 Gene3D G3DSA:3.40.190.10 145 334 7.9E-31 T 01-11-2018 MLA2C4_09750 83565b054bb75873a382b92e5c32b822 200 SUPERFAMILY SSF55469 7 200 7.98E-67 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_09750 83565b054bb75873a382b92e5c32b822 200 Pfam PF00881 Nitroreductase family 12 179 5.5E-23 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_09750 83565b054bb75873a382b92e5c32b822 200 Gene3D G3DSA:3.40.109.10 5 200 6.2E-80 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_09310 2e2833d523b5fa7eb9b5354a0ca8298e 313 Pfam PF00480 ROK family 6 303 4.4E-65 T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_09310 2e2833d523b5fa7eb9b5354a0ca8298e 313 Gene3D G3DSA:3.30.420.40 125 288 6.6E-88 T 01-11-2018 MLA2C4_09310 2e2833d523b5fa7eb9b5354a0ca8298e 313 Gene3D G3DSA:3.30.420.40 8 300 6.6E-88 T 01-11-2018 MLA2C4_09310 2e2833d523b5fa7eb9b5354a0ca8298e 313 ProSitePatterns PS01125 ROK family signature. 134 161 - T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_09310 2e2833d523b5fa7eb9b5354a0ca8298e 313 SUPERFAMILY SSF53067 4 307 6.22E-63 T 01-11-2018 MLA2C4_24870 3200ec0e67429852d60903b345d32066 98 Pfam PF13143 Protein of unknown function (DUF3986) 3 89 6.2E-33 T 01-11-2018 IPR025047 Protein of unknown function DUF3986 MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 Gene3D G3DSA:3.40.50.300 199 434 1.2E-86 T 01-11-2018 MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 Gene3D G3DSA:3.40.50.300 441 613 6.3E-57 T 01-11-2018 MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 SUPERFAMILY SSF52540 173 436 1.16E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 Pfam PF00271 Helicase conserved C-terminal domain 455 572 5.0E-20 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 SUPERFAMILY SSF50249 6 167 1.88E-26 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 Gene3D G3DSA:2.40.50.140 46 141 3.6E-9 T 01-11-2018 MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 SMART SM00487 253 442 2.9E-32 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 SMART SM00490 323 401 0.84 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 SMART SM00490 488 573 5.0E-22 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 Pfam PF17191 RecG wedge domain 12 163 3.9E-14 T 01-11-2018 IPR033454 RecG, wedge domain MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 6.8E-246 T 01-11-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 Pfam PF00270 DEAD/DEAH box helicase 260 415 2.5E-17 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_20145 0c5be12be4c908b5a17369ea09e1d7c7 682 SUPERFAMILY SSF52540 376 585 6.95E-42 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03145 fef7c92ff373e43e5bc6a65f2e682244 471 Gene3D G3DSA:1.20.1740.10 20 466 1.1E-129 T 01-11-2018 MLA2C4_03145 fef7c92ff373e43e5bc6a65f2e682244 471 Pfam PF13520 Amino acid permease 26 430 1.1E-64 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_03145 fef7c92ff373e43e5bc6a65f2e682244 471 PIRSF PIRSF006060 5 471 2.0E-92 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 4.6E-12 T 01-11-2018 IPR011096 FTP domain MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 390 406 2.4E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 411 422 2.4E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 481 497 2.4E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 Gene3D G3DSA:3.10.450.490 53 143 4.3E-6 T 01-11-2018 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 Gene3D G3DSA:1.10.390.10 404 566 4.3E-48 T 01-11-2018 IPR027268 Peptidase M4/M1, CTD superfamily MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 SUPERFAMILY SSF55486 246 566 8.42E-69 T 01-11-2018 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 402 566 5.2E-51 T 01-11-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 248 399 2.0E-34 T 01-11-2018 IPR013856 Peptidase M4 domain GO:0004222 MLA2C4_14495 bde777ecbe85947622e1079015eb4ad8 567 Gene3D G3DSA:3.10.170.10 247 403 5.4E-38 T 01-11-2018 MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 Gene3D G3DSA:3.40.50.720 1 258 1.5E-80 T 01-11-2018 MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 3.3E-110 T 01-11-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 5.1E-64 T 01-11-2018 MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 SUPERFAMILY SSF51735 4 257 1.5E-81 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.7E-11 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.7E-11 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 8.7E-11 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_21080 83ba655419de34a7bad741f5b647fd7d 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 1.8E-29 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 SMART SM00862 153 229 9.4E-29 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 Pfam PF00072 Response regulator receiver domain 6 115 1.4E-29 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 SMART SM00448 4 114 4.5E-44 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 Gene3D G3DSA:1.10.10.10 130 233 1.4E-36 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 SUPERFAMILY SSF52172 5 188 1.25E-40 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_01600 ce045518a03dcfe45f6ab074f86a4e43 233 Gene3D G3DSA:3.40.50.2300 2 129 2.1E-37 T 01-11-2018 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 PIRSF PIRSF001553 1 291 9.8E-134 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 1.9E-147 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 Pfam PF02629 CoA binding domain 6 99 1.4E-32 T 01-11-2018 IPR003781 CoA-binding GO:0048037 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 01-11-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 SMART SM00881 4 100 8.7E-37 T 01-11-2018 IPR003781 CoA-binding GO:0048037 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 Gene3D G3DSA:3.40.50.261 124 289 2.3E-71 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.8E-40 T 01-11-2018 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.8E-40 T 01-11-2018 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.8E-40 T 01-11-2018 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.8E-40 T 01-11-2018 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.943 T 01-11-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 Pfam PF00549 CoA-ligase 151 268 5.2E-18 T 01-11-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 01-11-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 Gene3D G3DSA:3.40.50.720 1 123 1.2E-52 T 01-11-2018 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 SUPERFAMILY SSF52210 123 287 9.03E-55 T 01-11-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MLA2C4_20045 36a9d133f07d823f73627e0431f160cf 300 SUPERFAMILY SSF51735 1 122 3.94E-44 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_00945 bc86f701b314b4f0f172b7f5cecc7f37 381 Gene3D G3DSA:3.90.1510.10 42 276 4.8E-140 T 01-11-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 MLA2C4_00945 bc86f701b314b4f0f172b7f5cecc7f37 381 Gene3D G3DSA:3.40.50.10350 2 362 4.8E-140 T 01-11-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold MLA2C4_00945 bc86f701b314b4f0f172b7f5cecc7f37 381 Pfam PF02595 Glycerate kinase family 3 374 3.3E-148 T 01-11-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MLA2C4_00945 bc86f701b314b4f0f172b7f5cecc7f37 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 1.7E-158 T 01-11-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MLA2C4_00945 bc86f701b314b4f0f172b7f5cecc7f37 381 PIRSF PIRSF006078 1 378 3.4E-141 T 01-11-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MLA2C4_00945 bc86f701b314b4f0f172b7f5cecc7f37 381 SUPERFAMILY SSF110738 2 375 9.55E-138 T 01-11-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 MLA2C4_08130 c550dcd5322e03eae88c3aa7eeec4021 235 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 200 1.2E-25 T 01-11-2018 IPR006343 DnaD domain MLA2C4_08130 c550dcd5322e03eae88c3aa7eeec4021 235 Pfam PF07261 Replication initiation and membrane attachment 131 201 6.1E-26 T 01-11-2018 IPR006343 DnaD domain MLA2C4_08130 c550dcd5322e03eae88c3aa7eeec4021 235 Gene3D G3DSA:1.10.10.10 1 115 1.6E-38 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08130 c550dcd5322e03eae88c3aa7eeec4021 235 SUPERFAMILY SSF158499 130 195 1.83E-19 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_08130 c550dcd5322e03eae88c3aa7eeec4021 235 Gene3D G3DSA:1.10.10.630 126 201 1.0E-31 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_08130 c550dcd5322e03eae88c3aa7eeec4021 235 SUPERFAMILY SSF46785 16 136 8.65E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23675 475cd9f75c30f1ececa5da21acf17f36 284 Pfam PF02517 CAAX protease self-immunity 134 217 5.2E-18 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_23340 2fc5917de875dd8f335005b10740a7f9 316 Gene3D G3DSA:1.10.287.850 1 97 7.4E-29 T 01-11-2018 MLA2C4_23340 2fc5917de875dd8f335005b10740a7f9 316 SUPERFAMILY SSF140453 3 92 3.01E-16 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_23340 2fc5917de875dd8f335005b10740a7f9 316 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 2.8E-23 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_23340 2fc5917de875dd8f335005b10740a7f9 316 Pfam PF06013 Proteins of 100 residues with WXG 3 88 1.1E-18 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_23340 2fc5917de875dd8f335005b10740a7f9 316 Pfam PF14449 Pre-toxin TG 127 187 5.2E-19 T 01-11-2018 IPR027797 Pre-toxin TG domain MLA2C4_06105 3829c0054ea091f3dda93fefd1a3ff88 163 Gene3D G3DSA:3.30.70.990 12 101 7.5E-63 T 01-11-2018 IPR035570 UPF0234, N-terminal MLA2C4_06105 3829c0054ea091f3dda93fefd1a3ff88 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.975 T 01-11-2018 IPR007551 Protein of unknown function DUF520 MLA2C4_06105 3829c0054ea091f3dda93fefd1a3ff88 163 SUPERFAMILY SSF89963 91 163 1.41E-25 T 01-11-2018 IPR036183 YajQ-like superfamily MLA2C4_06105 3829c0054ea091f3dda93fefd1a3ff88 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.8E-62 T 01-11-2018 IPR007551 Protein of unknown function DUF520 MLA2C4_06105 3829c0054ea091f3dda93fefd1a3ff88 163 SUPERFAMILY SSF89963 6 90 1.07E-30 T 01-11-2018 IPR036183 YajQ-like superfamily MLA2C4_06105 3829c0054ea091f3dda93fefd1a3ff88 163 Gene3D G3DSA:3.30.70.860 6 163 7.5E-63 T 01-11-2018 IPR035571 UPF0234-like, C-terminal MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 SUPERFAMILY SSF55874 412 578 7.6E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 577 3.5E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 534 3.5E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 558 3.5E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 520 3.5E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 SMART SM00387 469 580 1.5E-29 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 Gene3D G3DSA:1.10.287.130 281 417 1.3E-12 T 01-11-2018 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 SMART SM00388 355 423 6.1E-9 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 578 1.5E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 414 1.2E-8 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 SUPERFAMILY SSF47384 350 423 8.44E-12 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_05875 34ba90d3ab2eb8461594ed95feca479c 580 Gene3D G3DSA:3.30.565.10 428 580 3.4E-35 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 SUPERFAMILY SSF53623 106 315 8.5E-52 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 SUPERFAMILY SSF63418 5 103 2.09E-25 T 01-11-2018 IPR035911 MurE/MurF, N-terminal MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Gene3D G3DSA:3.40.1190.10 87 316 3.3E-69 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 458 35.987 T 01-11-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 320 398 1.2E-16 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Gene3D G3DSA:3.90.190.20 317 458 1.9E-41 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Gene3D G3DSA:3.40.1390.10 2 84 7.5E-24 T 01-11-2018 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 SUPERFAMILY SSF53244 319 457 1.76E-35 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 457 5.7E-139 T 01-11-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Pfam PF01225 Mur ligase family, catalytic domain 26 101 4.6E-11 T 01-11-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MLA2C4_01385 c5ac270c4cc4b9b910af37dcf8faebcf 458 Pfam PF08245 Mur ligase middle domain 111 298 1.9E-48 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 SUPERFAMILY SSF46689 18 88 4.14E-16 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 Gene3D G3DSA:1.10.10.60 17 59 3.7E-15 T 01-11-2018 MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 Gene3D G3DSA:1.10.357.10 61 205 1.6E-16 T 01-11-2018 MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.7E-7 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.7E-7 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 SUPERFAMILY SSF48498 92 203 1.08E-8 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_27650 cc2c1eb856fd472ef1e7035637a0ef7c 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 6.4E-13 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_08735 dd75323deac983566c61e276f6ff6bb3 257 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 134 1.2E-23 T 01-11-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G MLA2C4_08735 dd75323deac983566c61e276f6ff6bb3 257 Pfam PF00460 Flagella basal body rod protein 4 34 8.1E-7 T 01-11-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MLA2C4_08735 dd75323deac983566c61e276f6ff6bb3 257 SUPERFAMILY SSF117143 101 189 1.44E-12 T 01-11-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like MLA2C4_08735 dd75323deac983566c61e276f6ff6bb3 257 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 250 1.5E-10 T 01-11-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MLA2C4_05190 da9bba71e20d8071fab684517a4e34db 213 Gene3D G3DSA:3.40.50.360 1 213 1.0E-64 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_05190 da9bba71e20d8071fab684517a4e34db 213 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 210 27.097 T 01-11-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MLA2C4_05190 da9bba71e20d8071fab684517a4e34db 213 Pfam PF02525 Flavodoxin-like fold 3 205 2.4E-41 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_05190 da9bba71e20d8071fab684517a4e34db 213 SUPERFAMILY SSF52218 1 210 1.96E-45 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_19075 479c95b4a8de76b265dd519dfd25841b 303 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_19075 479c95b4a8de76b265dd519dfd25841b 303 Pfam PF00005 ABC transporter 24 164 1.2E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19075 479c95b4a8de76b265dd519dfd25841b 303 Gene3D G3DSA:3.40.50.300 1 253 1.0E-64 T 01-11-2018 MLA2C4_19075 479c95b4a8de76b265dd519dfd25841b 303 SMART SM00382 32 213 1.1E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19075 479c95b4a8de76b265dd519dfd25841b 303 SUPERFAMILY SSF52540 6 221 3.73E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 Gene3D G3DSA:1.10.10.10 1 91 6.6E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 SUPERFAMILY SSF53850 87 267 3.08E-23 T 01-11-2018 MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 Gene3D G3DSA:3.40.190.10 158 260 4.4E-25 T 01-11-2018 MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 Pfam PF03466 LysR substrate binding domain 89 266 5.9E-24 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 SUPERFAMILY SSF46785 1 86 1.24E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 Gene3D G3DSA:3.40.190.10 92 266 4.4E-25 T 01-11-2018 MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_24160 9dc42b1dd10981d43a3639c070cfdef7 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.0E-19 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 Gene3D G3DSA:3.50.50.60 209 498 1.3E-105 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 1.2E-39 T 01-11-2018 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 1.2E-39 T 01-11-2018 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 1.2E-39 T 01-11-2018 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 458 480 1.2E-39 T 01-11-2018 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 1.2E-39 T 01-11-2018 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 Gene3D G3DSA:3.40.30.80 2 198 6.7E-61 T 01-11-2018 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 508 5.3E-242 T 01-11-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 SUPERFAMILY SSF52833 103 194 1.55E-21 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 Pfam PF13192 Thioredoxin domain 125 193 1.5E-7 T 01-11-2018 IPR012336 Thioredoxin-like fold MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 01-11-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 Gene3D G3DSA:3.50.50.60 319 441 1.3E-105 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 483 6.9E-45 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 SUPERFAMILY SSF51905 194 504 3.27E-50 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 468 486 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 1.5E-64 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 PIRSF PIRSF000238 2 508 5.2E-258 T 01-11-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 MLA2C4_02025 fde1a835fc681f8e9075697bec4e173d 508 SUPERFAMILY SSF52833 2 100 1.7E-30 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_21805 28de21849a696c34c96bf88bb6d35297 242 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 233 1.9E-43 T 01-11-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MLA2C4_21805 28de21849a696c34c96bf88bb6d35297 242 SUPERFAMILY SSF51695 1 235 1.41E-73 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_21805 28de21849a696c34c96bf88bb6d35297 242 Gene3D G3DSA:3.20.20.190 1 239 3.5E-83 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_06735 8119e6a6f2662dd971c26263f41f4279 70 Pfam PF12728 Helix-turn-helix domain 11 54 3.3E-11 T 01-11-2018 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 SUPERFAMILY SSF48150 1 210 4.55E-75 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 Gene3D G3DSA:1.10.1670.10 16 205 4.6E-81 T 01-11-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.2E-4 T 01-11-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 PIRSF PIRSF001435 1 213 1.8E-59 T 01-11-2018 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.687 T 01-11-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 Pfam PF00633 Helix-hairpin-helix motif 101 128 1.6E-9 T 01-11-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 TIGRFAM TIGR01083 nth: endonuclease III 6 196 1.4E-86 T 01-11-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 8.4E-26 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 SMART SM00525 188 208 1.0E-4 T 01-11-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 01-11-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 Gene3D G3DSA:1.10.340.30 22 133 4.6E-81 T 01-11-2018 MLA2C4_08135 5d2531a31ad7923029ee556021eab71d 215 SMART SM00478 39 187 2.4E-69 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_24955 1ccc53e1c19c2bbecc9a8b2b73954522 78 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 1.6E-36 T 01-11-2018 IPR002696 Putative membrane protein insertion efficiency factor MLA2C4_24955 1ccc53e1c19c2bbecc9a8b2b73954522 78 Pfam PF01809 Haemolytic domain 2 68 4.8E-33 T 01-11-2018 IPR002696 Putative membrane protein insertion efficiency factor MLA2C4_24955 1ccc53e1c19c2bbecc9a8b2b73954522 78 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.387 T 01-11-2018 IPR002696 Putative membrane protein insertion efficiency factor MLA2C4_24955 1ccc53e1c19c2bbecc9a8b2b73954522 78 SMART SM01234 1 68 1.8E-50 T 01-11-2018 IPR002696 Putative membrane protein insertion efficiency factor MLA2C4_24955 1ccc53e1c19c2bbecc9a8b2b73954522 78 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 65 7.0E-24 T 01-11-2018 IPR002696 Putative membrane protein insertion efficiency factor MLA2C4_15060 43acdc122c936cb8ae36dc10f18cf482 154 SUPERFAMILY SSF47413 8 62 2.68E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_15060 43acdc122c936cb8ae36dc10f18cf482 154 SMART SM00530 13 67 8.6E-8 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_15060 43acdc122c936cb8ae36dc10f18cf482 154 Pfam PF01381 Helix-turn-helix 14 48 1.7E-8 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_15060 43acdc122c936cb8ae36dc10f18cf482 154 Gene3D G3DSA:1.10.260.40 2 67 4.9E-11 T 01-11-2018 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SMART SM00060 485 557 9.7E-12 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Gene3D G3DSA:3.10.50.10 338 421 1.3E-158 T 01-11-2018 IPR029070 Chitinase insertion domain superfamily MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SUPERFAMILY SSF49265 479 563 9.73E-15 T 01-11-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Gene3D G3DSA:3.20.20.80 41 450 1.3E-158 T 01-11-2018 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Pfam PF00553 Cellulose binding domain 580 673 1.7E-18 T 01-11-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SUPERFAMILY SSF54556 339 421 2.14E-22 T 01-11-2018 IPR029070 Chitinase insertion domain superfamily MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Pfam PF00041 Fibronectin type III domain 488 559 3.6E-9 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SMART SM00636 39 450 1.7E-161 T 01-11-2018 IPR011583 Chitinase II GO:0008061 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Gene3D G3DSA:2.60.40.10 483 567 6.6E-19 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SUPERFAMILY SSF49384 574 666 1.53E-21 T 01-11-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Gene3D G3DSA:2.60.40.290 579 674 7.4E-21 T 01-11-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 Pfam PF00704 Glycosyl hydrolases family 18 40 450 2.6E-100 T 01-11-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SUPERFAMILY SSF51445 34 451 2.01E-102 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 SMART SM00637 579 671 1.1E-28 T 01-11-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 MLA2C4_02330 3d6fca69aab0b0b1c7e3add45c87f802 674 ProSitePatterns PS01095 Chitinases family 18 active site. 201 209 - T 01-11-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MLA2C4_15155 2131bc9be75d272fe8de5f0e4e9aa746 152 Gene3D G3DSA:3.40.630.30 2 146 4.3E-30 T 01-11-2018 MLA2C4_15155 2131bc9be75d272fe8de5f0e4e9aa746 152 SUPERFAMILY SSF55729 12 136 2.09E-14 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15155 2131bc9be75d272fe8de5f0e4e9aa746 152 Pfam PF13673 Acetyltransferase (GNAT) domain 26 135 9.0E-10 T 01-11-2018 IPR000182 GNAT domain MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 12 255 2.1E-94 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 2.9E-41 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 2.9E-41 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 2.9E-41 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 2.9E-41 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 2.9E-41 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 2.9E-41 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 Gene3D G3DSA:3.40.1190.20 1 268 1.8E-98 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 Pfam PF02110 Hydroxyethylthiazole kinase family 12 253 3.3E-91 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 SUPERFAMILY SSF53613 11 266 7.64E-60 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 260 33.23 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02275 0b4c1f2a63f292aa4692d07c3c401323 268 PIRSF PIRSF000513 4 268 3.2E-96 T 01-11-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 Pfam PF09383 NIL domain 263 326 1.6E-19 T 01-11-2018 IPR018449 NIL domain MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 SMART SM00930 260 334 1.5E-27 T 01-11-2018 IPR018449 NIL domain MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 SUPERFAMILY SSF55021 250 328 2.63E-20 T 01-11-2018 MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 SMART SM00382 30 226 8.9E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 Gene3D G3DSA:3.30.70.260 233 336 5.7E-28 T 01-11-2018 MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 SUPERFAMILY SSF52540 1 240 1.04E-86 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 Gene3D G3DSA:3.40.50.300 1 232 1.5E-79 T 01-11-2018 MLA2C4_01865 ba4bc228cb176fc7096efe2e1f1e21d4 339 Pfam PF00005 ABC transporter 22 169 1.1E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 SMART SM00382 38 150 1.9E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Gene3D G3DSA:1.10.8.60 150 225 2.0E-16 T 01-11-2018 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 SUPERFAMILY SSF48019 238 420 1.87E-70 T 01-11-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 6.2E-15 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 SUPERFAMILY SSF52540 3 228 1.02E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Gene3D G3DSA:1.10.3710.10 332 427 1.1E-25 T 01-11-2018 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 3.2E-66 T 01-11-2018 IPR021886 MgsA AAA+ ATPase C-terminal MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Gene3D G3DSA:1.20.272.10 228 331 1.0E-40 T 01-11-2018 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Gene3D G3DSA:3.40.50.300 1 149 2.6E-40 T 01-11-2018 MLA2C4_22945 237c613399b515e12bb44d0c50e9a6ba 428 Pfam PF16193 AAA C-terminal domain 172 252 3.1E-24 T 01-11-2018 IPR032423 AAA C-terminal domain MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 SUPERFAMILY SSF46955 5 113 1.68E-25 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 1.3E-6 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 1.3E-6 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 1.3E-6 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 Pfam PF13411 MerR HTH family regulatory protein 5 70 4.9E-16 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 SMART SM00422 4 73 1.7E-26 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26740 bfc64ba64a7f6e8aff549350661eff4b 253 Gene3D G3DSA:1.10.1660.10 2 131 3.4E-32 T 01-11-2018 MLA2C4_08400 8f096b223f8671ba5278096e36fef4f6 516 Gene3D G3DSA:1.20.1730.10 21 474 2.2E-68 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily MLA2C4_08400 8f096b223f8671ba5278096e36fef4f6 516 Pfam PF00474 Sodium:solute symporter family 33 434 9.1E-126 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_08400 8f096b223f8671ba5278096e36fef4f6 516 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 416 436 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site MLA2C4_08400 8f096b223f8671ba5278096e36fef4f6 516 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site MLA2C4_08400 8f096b223f8671ba5278096e36fef4f6 516 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 1.3E-92 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_15100 7704087821f203eb544283340442550d 163 Gene3D G3DSA:1.25.40.20 3 162 1.4E-40 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_15100 7704087821f203eb544283340442550d 163 Pfam PF12796 Ankyrin repeats (3 copies) 9 100 1.2E-14 T 01-11-2018 IPR020683 Ankyrin repeat-containing domain MLA2C4_15100 7704087821f203eb544283340442550d 163 PRINTS PR01415 Ankyrin repeat signature 37 52 2.1E-6 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_15100 7704087821f203eb544283340442550d 163 PRINTS PR01415 Ankyrin repeat signature 87 101 2.1E-6 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_15100 7704087821f203eb544283340442550d 163 SMART SM00248 71 100 0.0024 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_15100 7704087821f203eb544283340442550d 163 SMART SM00248 104 133 0.012 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_15100 7704087821f203eb544283340442550d 163 SMART SM00248 36 65 7.1E-5 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_15100 7704087821f203eb544283340442550d 163 Pfam PF13606 Ankyrin repeat 105 129 9.5E-4 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_15100 7704087821f203eb544283340442550d 163 SUPERFAMILY SSF48403 8 158 2.19E-37 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 SMART SM00028 172 205 1.8 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 SMART SM00028 317 350 170.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 SMART SM00028 212 245 46.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 Pfam PF13374 Tetratricopeptide repeat 171 201 2.0E-4 T 01-11-2018 MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 Pfam PF13181 Tetratricopeptide repeat 214 244 0.18 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 SUPERFAMILY SSF48452 98 275 6.83E-13 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10925 0d90f8209cca3411801e84d5ce71fba4 357 Gene3D G3DSA:1.25.40.10 2 356 1.2E-89 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10940 0fc2ee99408324fc8cd8d38b3c40f8d3 215 SUPERFAMILY SSF109604 4 213 3.87E-76 T 01-11-2018 MLA2C4_10940 0fc2ee99408324fc8cd8d38b3c40f8d3 215 Gene3D G3DSA:1.20.58.1910 102 215 4.6E-49 T 01-11-2018 MLA2C4_10940 0fc2ee99408324fc8cd8d38b3c40f8d3 215 Pfam PF01966 HD domain 28 126 2.1E-9 T 01-11-2018 IPR006674 HD domain MLA2C4_10940 0fc2ee99408324fc8cd8d38b3c40f8d3 215 SMART SM00471 22 136 2.0E-8 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_10940 0fc2ee99408324fc8cd8d38b3c40f8d3 215 Gene3D G3DSA:1.10.472.50 1 99 8.6E-37 T 01-11-2018 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 Pfam PF00224 Pyruvate kinase, barrel domain 10 335 5.0E-115 T 01-11-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 SUPERFAMILY SSF50800 69 164 4.36E-26 T 01-11-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 10 337 7.4E-133 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 Gene3D G3DSA:3.20.20.60 10 336 3.8E-131 T 01-11-2018 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 Gene3D G3DSA:2.40.33.10 70 164 3.8E-131 T 01-11-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 58 74 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 214 240 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 266 290 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 310 326 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 183 197 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 291 309 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 PRINTS PR01050 Pyruvate kinase family signature 241 265 2.2E-57 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_17450 aa9f08f7f724216edbe5f5b2961d3342 356 SUPERFAMILY SSF51621 9 334 4.89E-85 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 Gene3D G3DSA:3.40.50.1100 57 387 1.9E-194 T 01-11-2018 MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 381 4.4E-45 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 Gene3D G3DSA:3.40.50.1100 13 209 1.9E-194 T 01-11-2018 MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 01-11-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 SUPERFAMILY SSF53686 6 392 7.86E-149 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 10 393 4.3E-198 T 01-11-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 394 54.054 T 01-11-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_06515 bb6bcf48242ca7e34a69a22837d1dacd 397 PIRSF PIRSF001413 1 397 4.4E-169 T 01-11-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 8.0E-44 T 01-11-2018 IPR000238 Ribosome-binding factor A GO:0006364 MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 SUPERFAMILY SSF89919 3 110 8.9E-37 T 01-11-2018 IPR023799 Ribosome-binding factor A domain superfamily MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 01-11-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 Pfam PF02033 Ribosome-binding factor A 4 107 1.5E-34 T 01-11-2018 IPR000238 Ribosome-binding factor A GO:0006364 MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 28.179 T 01-11-2018 IPR000238 Ribosome-binding factor A GO:0006364 MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 1.4E-43 T 01-11-2018 IPR000238 Ribosome-binding factor A GO:0006364 MLA2C4_19925 d8d128e84ffb2dd6140a3923e048c34a 118 Gene3D G3DSA:3.30.300.20 1 116 3.2E-40 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 Gene3D G3DSA:3.90.180.10 9 318 3.8E-96 T 01-11-2018 MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.0E-10 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 SUPERFAMILY SSF50129 1 144 1.67E-36 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 Gene3D G3DSA:3.40.50.720 123 265 3.8E-96 T 01-11-2018 MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 01-11-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 SMART SM00829 10 319 4.5E-24 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 SUPERFAMILY SSF51735 112 272 2.48E-39 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_18110 2cd90de1185a68ed36dd3dfde0bb05f6 321 Pfam PF00107 Zinc-binding dehydrogenase 151 259 5.8E-26 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_19810 c63dbb08748ae9c37250b483aa8f912b 424 Gene3D G3DSA:3.30.830.10 7 237 5.6E-63 T 01-11-2018 MLA2C4_19810 c63dbb08748ae9c37250b483aa8f912b 424 SUPERFAMILY SSF63411 243 411 1.6E-32 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_19810 c63dbb08748ae9c37250b483aa8f912b 424 SUPERFAMILY SSF63411 12 232 1.54E-25 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_19810 c63dbb08748ae9c37250b483aa8f912b 424 Gene3D G3DSA:3.30.830.10 238 424 2.5E-43 T 01-11-2018 MLA2C4_19810 c63dbb08748ae9c37250b483aa8f912b 424 Pfam PF05193 Peptidase M16 inactive domain 184 356 7.3E-28 T 01-11-2018 IPR007863 Peptidase M16, C-terminal MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 Pfam PF00155 Aminotransferase class I and II 31 347 1.6E-50 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 SUPERFAMILY SSF53383 5 343 7.51E-75 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 353 57.703 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 Gene3D G3DSA:3.90.1150.10 8 344 1.5E-106 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 Gene3D G3DSA:3.40.640.10 43 267 1.5E-106 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 01-11-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MLA2C4_15560 d5c1be79dbff8ffe20e33fddb3a3b6a5 366 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 351 2.1E-101 T 01-11-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MLA2C4_01875 37a21bcc48215cbe047fd219e2a3597d 280 SUPERFAMILY SSF53850 30 269 1.74E-83 T 01-11-2018 MLA2C4_01875 37a21bcc48215cbe047fd219e2a3597d 280 Gene3D G3DSA:3.40.190.10 108 218 9.7E-99 T 01-11-2018 MLA2C4_01875 37a21bcc48215cbe047fd219e2a3597d 280 Pfam PF03180 NLPA lipoprotein 31 266 4.5E-84 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_01875 37a21bcc48215cbe047fd219e2a3597d 280 PIRSF PIRSF002854 1 270 7.8E-104 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_01875 37a21bcc48215cbe047fd219e2a3597d 280 Gene3D G3DSA:3.40.190.10 32 260 9.7E-99 T 01-11-2018 MLA2C4_09300 beadf5dd282da9a3568ec9a4be285816 281 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 280 1.2E-98 T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_09300 beadf5dd282da9a3568ec9a4be285816 281 Pfam PF01116 Fructose-bisphosphate aldolase class-II 7 279 1.2E-100 T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_09300 beadf5dd282da9a3568ec9a4be285816 281 Gene3D G3DSA:3.20.20.70 1 281 1.0E-107 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_09300 beadf5dd282da9a3568ec9a4be285816 281 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 72 83 - T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_09300 beadf5dd282da9a3568ec9a4be285816 281 PIRSF PIRSF001359 1 281 2.4E-105 T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_09300 beadf5dd282da9a3568ec9a4be285816 281 SUPERFAMILY SSF51569 7 280 1.76E-97 T 01-11-2018 MLA2C4_27300 2bba74cbe4d24cf1d115b0a7b5adbef7 255 Gene3D G3DSA:3.20.20.140 1 255 3.5E-99 T 01-11-2018 MLA2C4_27300 2bba74cbe4d24cf1d115b0a7b5adbef7 255 SUPERFAMILY SSF89550 1 206 7.65E-16 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MLA2C4_27300 2bba74cbe4d24cf1d115b0a7b5adbef7 255 PIRSF PIRSF016557 1 255 8.7E-114 T 01-11-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 MLA2C4_02225 6205194878be0f1170c9e1b3f02ae4ef 106 Gene3D G3DSA:1.10.10.10 11 104 4.7E-16 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_02225 6205194878be0f1170c9e1b3f02ae4ef 106 Pfam PF03551 Transcriptional regulator PadR-like family 20 86 8.5E-13 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_02225 6205194878be0f1170c9e1b3f02ae4ef 106 SUPERFAMILY SSF46785 9 96 5.46E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_06600 cc802d6791786150f431375206c42ac1 69 SUPERFAMILY SSF47413 2 63 2.95E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_06600 cc802d6791786150f431375206c42ac1 69 Pfam PF01381 Helix-turn-helix 7 57 1.5E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_06600 cc802d6791786150f431375206c42ac1 69 SMART SM00530 4 59 2.6E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_06600 cc802d6791786150f431375206c42ac1 69 Gene3D G3DSA:1.10.260.40 1 65 6.6E-27 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 262 315 1.6E-18 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Gene3D G3DSA:3.40.50.740 323 782 1.6E-162 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 SUPERFAMILY SSF53706 255 788 8.64E-194 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 PIRSF PIRSF036643 1 968 0.0 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 SUPERFAMILY SSF54862 136 218 9.42E-17 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 SMART SM00926 261 315 3.3E-18 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 2.0E-21 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 78 1.2E-17 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 SMART SM00929 85 126 1.9E-12 T 01-11-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 1.5E-246 T 01-11-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 SUPERFAMILY SSF54292 5 128 6.29E-33 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Gene3D G3DSA:3.40.228.10 396 595 1.6E-162 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Pfam PF12838 4Fe-4S dicluster domain 150 208 2.3E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Gene3D G3DSA:3.10.20.740 5 126 1.6E-31 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Gene3D G3DSA:2.40.40.20 816 942 5.9E-27 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Pfam PF00384 Molybdopterin oxidoreductase 318 742 1.2E-87 T 01-11-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Gene3D G3DSA:3.30.70.20 130 212 2.6E-20 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 2.3E-10 T 01-11-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 Gene3D G3DSA:2.20.25.90 261 316 4.6E-19 T 01-11-2018 MLA2C4_18545 974cd36f744f8782be65e1c688173bd0 979 SUPERFAMILY SSF50692 789 936 8.14E-35 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MLA2C4_24140 f402253d877c096c70f68e3d50369c9f 65 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 39 53 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_24140 f402253d877c096c70f68e3d50369c9f 65 Gene3D G3DSA:1.10.8.910 6 65 4.6E-31 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_24140 f402253d877c096c70f68e3d50369c9f 65 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 60 1.1E-22 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_24140 f402253d877c096c70f68e3d50369c9f 65 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 21 30 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_11680 12c1dfa727276a3d6bff18de83511bc9 138 Pfam PF06356 Protein of unknown function (DUF1064) 2 115 3.1E-44 T 01-11-2018 IPR009414 Protein of unknown function DUF1064 MLA2C4_01260 8ae6b8ae0bb247951be11e310b974edd 397 SMART SM00387 298 388 1.2E-8 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_01260 8ae6b8ae0bb247951be11e310b974edd 397 Gene3D G3DSA:3.30.565.10 264 387 2.6E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01260 8ae6b8ae0bb247951be11e310b974edd 397 Pfam PF07730 Histidine kinase 194 259 7.1E-18 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_01260 8ae6b8ae0bb247951be11e310b974edd 397 SUPERFAMILY SSF55874 263 386 2.88E-21 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01260 8ae6b8ae0bb247951be11e310b974edd 397 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 301 387 1.3E-5 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_27280 2bd0941201ff9d06edad821794d2ff28 358 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 346 1.4E-172 T 01-11-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MLA2C4_27280 2bd0941201ff9d06edad821794d2ff28 358 Gene3D G3DSA:3.90.25.10 195 344 3.0E-167 T 01-11-2018 MLA2C4_27280 2bd0941201ff9d06edad821794d2ff28 358 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 349 55.027 T 01-11-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 MLA2C4_27280 2bd0941201ff9d06edad821794d2ff28 358 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 339 1.8E-155 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_27280 2bd0941201ff9d06edad821794d2ff28 358 Gene3D G3DSA:3.40.50.720 4 330 3.0E-167 T 01-11-2018 MLA2C4_27280 2bd0941201ff9d06edad821794d2ff28 358 SUPERFAMILY SSF51735 2 340 1.4E-80 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07560 84b89ccd322656ae2a1b3acd5297caa7 423 Pfam PF01551 Peptidase family M23 314 411 1.2E-29 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_07560 84b89ccd322656ae2a1b3acd5297caa7 423 Gene3D G3DSA:1.20.5.1160 33 115 1.0E-5 T 01-11-2018 MLA2C4_07560 84b89ccd322656ae2a1b3acd5297caa7 423 SUPERFAMILY SSF51261 235 421 6.8E-45 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_07560 84b89ccd322656ae2a1b3acd5297caa7 423 Gene3D G3DSA:2.70.70.10 244 422 1.0E-39 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_11225 430995df702834eac7e12240fd44ca2b 61 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 60 18.949 T 01-11-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MLA2C4_11225 430995df702834eac7e12240fd44ca2b 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.2E-6 T 01-11-2018 MLA2C4_11225 430995df702834eac7e12240fd44ca2b 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.2E-6 T 01-11-2018 MLA2C4_11225 430995df702834eac7e12240fd44ca2b 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.2E-6 T 01-11-2018 MLA2C4_11225 430995df702834eac7e12240fd44ca2b 61 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 7.1E-20 T 01-11-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MLA2C4_11225 430995df702834eac7e12240fd44ca2b 61 Pfam PF02416 mttA/Hcf106 family 5 56 5.5E-22 T 01-11-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 47.403 T 01-11-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 Gene3D G3DSA:3.40.50.720 1 149 2.5E-63 T 01-11-2018 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 Gene3D G3DSA:3.90.110.10 150 310 7.6E-62 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 PIRSF PIRSF000102 2 311 4.0E-106 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 8.8E-28 T 01-11-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 5.8E-31 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 5.8E-31 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 5.8E-31 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 5.8E-31 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 5.8E-31 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 4.4E-163 T 01-11-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 SUPERFAMILY SSF51735 2 147 3.8E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 2.3E-42 T 01-11-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_23855 4ca17366652c753665d7dd7161f251ef 312 SUPERFAMILY SSF56327 151 309 6.77E-52 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_07925 ab57391428cd0bb9a03ff2ba4bbc9527 83 Pfam PF14069 Stage VI sporulation protein F 6 77 6.8E-30 T 01-11-2018 IPR025942 Stage VI sporulation protein F MLA2C4_04230 3dd7563d4ea15400d8943e29cc075e45 564 Gene3D G3DSA:3.30.950.30 1 145 6.3E-27 T 01-11-2018 IPR038461 Schlafen, AAA domain superfamily MLA2C4_04230 3dd7563d4ea15400d8943e29cc075e45 564 Pfam PF04326 Putative DNA-binding domain 24 144 3.8E-12 T 01-11-2018 IPR007421 Schlafen, AAA domain GO:0005524 MLA2C4_04230 3dd7563d4ea15400d8943e29cc075e45 564 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 315 399 1.6E-16 T 01-11-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain MLA2C4_04230 3dd7563d4ea15400d8943e29cc075e45 564 Gene3D G3DSA:3.30.565.60 244 402 4.0E-32 T 01-11-2018 IPR038475 RecG, C-terminal domain superfamily MLA2C4_13785 1b5751172ffd74336e0e0f60c6549b08 233 Pfam PF13649 Methyltransferase domain 53 154 1.3E-12 T 01-11-2018 MLA2C4_13785 1b5751172ffd74336e0e0f60c6549b08 233 Gene3D G3DSA:3.40.50.150 38 233 2.6E-22 T 01-11-2018 MLA2C4_13785 1b5751172ffd74336e0e0f60c6549b08 233 SUPERFAMILY SSF53335 21 200 1.61E-23 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_17335 367fa00ea9676f4166b93b1154713602 292 Pfam PF02361 Cobalt transport protein 19 211 9.8E-10 T 01-11-2018 IPR003339 ABC/ECF transporter, transmembrane component MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 Gene3D G3DSA:3.40.50.300 3 321 1.2E-102 T 01-11-2018 MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 7.8E-20 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 SMART SM00382 41 233 8.6E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 Pfam PF00005 ABC transporter 33 184 6.1E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 3.1E-29 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01315 5d09212f6cb4943b8468b99e44c8c709 321 SUPERFAMILY SSF52540 40 318 3.01E-74 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19830 f2477e9bb24aa8f7d4f347856147b248 358 SUPERFAMILY SSF53822 51 278 5.5E-15 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_19830 f2477e9bb24aa8f7d4f347856147b248 358 Gene3D G3DSA:3.40.50.2300 144 340 1.9E-110 T 01-11-2018 MLA2C4_19830 f2477e9bb24aa8f7d4f347856147b248 358 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 39 345 3.5E-88 T 01-11-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 MLA2C4_19830 f2477e9bb24aa8f7d4f347856147b248 358 Gene3D G3DSA:3.40.50.2300 41 304 1.9E-110 T 01-11-2018 MLA2C4_28300 edc11267c5480d54cbd58a7102438695 292 Pfam PF13186 Iron-sulfur cluster-binding domain 219 284 4.4E-12 T 01-11-2018 IPR023885 4Fe4S-binding SPASM domain MLA2C4_28300 edc11267c5480d54cbd58a7102438695 292 SUPERFAMILY SSF102114 7 287 6.93E-36 T 01-11-2018 MLA2C4_28300 edc11267c5480d54cbd58a7102438695 292 Pfam PF13394 4Fe-4S single cluster domain 12 89 3.5E-5 T 01-11-2018 MLA2C4_28300 edc11267c5480d54cbd58a7102438695 292 Pfam PF04055 Radical SAM superfamily 10 113 6.0E-13 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_10455 3f389eaa362ea97f16c7b74fd330d850 175 Pfam PF07609 Protein of unknown function (DUF1572) 3 164 1.0E-75 T 01-11-2018 IPR011466 Protein of unknown function DUF1572 MLA2C4_10455 3f389eaa362ea97f16c7b74fd330d850 175 Gene3D G3DSA:1.20.120.450 9 150 8.7E-17 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_10455 3f389eaa362ea97f16c7b74fd330d850 175 SUPERFAMILY SSF109854 7 151 1.36E-20 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_24315 b228ca30b17a31b92f74dadf0208b038 338 Gene3D G3DSA:3.10.570.10 52 221 3.0E-57 T 01-11-2018 MLA2C4_24315 b228ca30b17a31b92f74dadf0208b038 338 Gene3D G3DSA:3.30.300.190 222 338 3.2E-39 T 01-11-2018 MLA2C4_24315 b228ca30b17a31b92f74dadf0208b038 338 PIRSF PIRSF012509 1 338 2.3E-91 T 01-11-2018 IPR011426 CamS sex pheromone cAM373 MLA2C4_24315 b228ca30b17a31b92f74dadf0208b038 338 Pfam PF07537 CamS sex pheromone cAM373 precursor 118 331 5.6E-47 T 01-11-2018 IPR011426 CamS sex pheromone cAM373 MLA2C4_24315 b228ca30b17a31b92f74dadf0208b038 338 Pfam PF07537 CamS sex pheromone cAM373 precursor 67 114 3.2E-7 T 01-11-2018 IPR011426 CamS sex pheromone cAM373 MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 50.091 T 01-11-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 01-11-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 Gene3D G3DSA:3.40.640.10 17 256 1.3E-90 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 Pfam PF00266 Aminotransferase class-V 4 348 2.3E-53 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 357 1.4E-158 T 01-11-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 Gene3D G3DSA:3.90.1150.10 257 359 2.1E-38 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 PIRSF PIRSF000525 1 360 4.6E-154 T 01-11-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MLA2C4_17115 4bb32ffbbb907e51bb0e01f96497f6b3 360 SUPERFAMILY SSF53383 1 356 4.7E-112 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 Gene3D G3DSA:3.10.290.10 1 54 8.4E-19 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 SUPERFAMILY SSF55120 58 222 3.36E-39 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 Pfam PF00849 RNA pseudouridylate synthase 61 187 6.2E-14 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 Pfam PF01479 S4 domain 2 46 1.5E-11 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 SMART SM00363 1 61 3.4E-10 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 96 110 - T 01-11-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 Gene3D G3DSA:3.30.70.1560 126 199 1.1E-53 T 01-11-2018 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 217 3.2E-47 T 01-11-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 Gene3D G3DSA:3.30.70.580 62 220 1.1E-53 T 01-11-2018 MLA2C4_12270 94abf995c2fa8397a47ff269616f82a3 235 SUPERFAMILY SSF55174 1 54 1.65E-12 T 01-11-2018 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 SUPERFAMILY SSF52540 138 434 3.36E-73 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 SUPERFAMILY SSF52540 5 167 9.82E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.959 T 01-11-2018 IPR016484 GTP-binding protein EngA GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Gene3D G3DSA:3.40.50.300 170 352 5.9E-56 T 01-11-2018 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Gene3D G3DSA:3.30.300.20 353 436 1.8E-35 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 2.7E-179 T 01-11-2018 IPR016484 GTP-binding protein EngA GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 339 6.8E-25 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 146 1.7E-23 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 4.6E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 4.6E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 5.0E-34 T 01-11-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Gene3D G3DSA:3.40.50.300 1 162 2.5E-46 T 01-11-2018 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 5.6E-26 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.1E-24 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_07915 892aaa54275a7d8b3ca8d9bced6c2fdd 436 PIRSF PIRSF006485 2 436 3.5E-172 T 01-11-2018 IPR016484 GTP-binding protein EngA GO:0005525 MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 Pfam PF00072 Response regulator receiver domain 5 113 2.5E-26 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 Gene3D G3DSA:1.10.10.10 131 229 1.1E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 SUPERFAMILY SSF52172 2 128 4.55E-40 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 SMART SM00448 3 113 3.2E-43 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 Gene3D G3DSA:3.40.50.2300 1 130 6.6E-38 T 01-11-2018 MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 6.0E-27 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 SUPERFAMILY SSF46894 128 228 3.68E-32 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_23590 b550ea643c9e56219a26d76d17ffc604 230 SMART SM00862 151 227 1.2E-27 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Gene3D G3DSA:2.30.30.40 57 120 2.0E-18 T 01-11-2018 MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Gene3D G3DSA:2.30.30.40 214 276 1.5E-15 T 01-11-2018 MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 SUPERFAMILY SSF50044 83 117 2.45E-5 T 01-11-2018 IPR036028 SH3-like domain superfamily GO:0005515 MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 SUPERFAMILY SSF54001 293 418 2.19E-31 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 SUPERFAMILY SSF50044 244 283 5.98E-5 T 01-11-2018 IPR036028 SH3-like domain superfamily GO:0005515 MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 SMART SM00287 57 118 9.1E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 SMART SM00287 213 274 1.3E-8 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 SMART SM00287 129 191 2.0E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Gene3D G3DSA:3.90.1720.10 277 416 2.4E-30 T 01-11-2018 MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Pfam PF08239 Bacterial SH3 domain 222 272 6.8E-14 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Pfam PF08239 Bacterial SH3 domain 66 115 3.4E-15 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Pfam PF08239 Bacterial SH3 domain 137 187 4.0E-16 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Pfam PF00877 NlpC/P60 family 313 416 6.0E-24 T 01-11-2018 IPR000064 Endopeptidase, NLPC/P60 domain MLA2C4_09920 12b81f3edc48f121c55d38089f36a774 420 Gene3D G3DSA:2.30.30.40 129 187 1.3E-20 T 01-11-2018 MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 SMART SM00418 3 81 3.1E-30 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 Gene3D G3DSA:1.10.10.10 1 87 5.9E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 4.0E-18 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 3.1E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 3.1E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 3.1E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_25160 4b863cf52f4df920fe4fbd8404d596d1 90 SUPERFAMILY SSF46785 3 80 1.3E-27 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_06830 4d7e13a1816a90ca027d22cc38309d2c 795 Pfam PF05547 Immune inhibitor A peptidase M6 150 791 0.0 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_06830 4d7e13a1816a90ca027d22cc38309d2c 795 SUPERFAMILY SSF55486 280 429 9.61E-17 T 01-11-2018 MLA2C4_06830 4d7e13a1816a90ca027d22cc38309d2c 795 PIRSF PIRSF007519 1 795 0.0 T 01-11-2018 IPR012300 Peptidase M6, InhA MLA2C4_06830 4d7e13a1816a90ca027d22cc38309d2c 795 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 183 492 5.3E-87 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_14245 f70cf082f6c8dddf3ee166853aaa65a3 148 SUPERFAMILY SSF55811 5 142 2.3E-24 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_14245 f70cf082f6c8dddf3ee166853aaa65a3 148 PRINTS PR00502 NUDIX hydrolase family signature 29 43 1.2E-6 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_14245 f70cf082f6c8dddf3ee166853aaa65a3 148 PRINTS PR00502 NUDIX hydrolase family signature 43 58 1.2E-6 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_14245 f70cf082f6c8dddf3ee166853aaa65a3 148 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_14245 f70cf082f6c8dddf3ee166853aaa65a3 148 Pfam PF00293 NUDIX domain 6 115 1.3E-16 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_14245 f70cf082f6c8dddf3ee166853aaa65a3 148 Gene3D G3DSA:3.90.79.10 1 138 1.8E-30 T 01-11-2018 MLA2C4_10390 af536eb0b37b7befc9a89e1cc6d96bd0 168 Gene3D G3DSA:3.10.129.10 1 168 8.0E-59 T 01-11-2018 MLA2C4_10390 af536eb0b37b7befc9a89e1cc6d96bd0 168 Pfam PF03061 Thioesterase superfamily 28 100 8.2E-13 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_10390 af536eb0b37b7befc9a89e1cc6d96bd0 168 SUPERFAMILY SSF54637 8 156 8.85E-44 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_03230 707a0b40144e5d24be9a5385cf7b39f5 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 7.2E-24 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_03230 707a0b40144e5d24be9a5385cf7b39f5 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.556 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_03230 707a0b40144e5d24be9a5385cf7b39f5 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 4.0E-26 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_03230 707a0b40144e5d24be9a5385cf7b39f5 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 5.5E-28 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 357 370 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 SUPERFAMILY SSF90123 2 315 2.88E-49 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 Pfam PF00005 ABC transporter 345 482 2.5E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 Pfam PF00664 ABC transporter transmembrane region 20 288 1.2E-22 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 Gene3D G3DSA:3.40.50.300 316 548 8.7E-64 T 01-11-2018 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 Gene3D G3DSA:1.20.1560.10 1 315 2.1E-45 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 SUPERFAMILY SSF52540 330 542 1.36E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18800 d55b59bca9a4c50fde82c32a7b8775ce 549 SMART SM00382 353 528 4.5E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_24660 f8c4380cbf0716511c882144d60f506b 165 Gene3D G3DSA:3.30.70.1450 85 161 2.3E-16 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_24660 f8c4380cbf0716511c882144d60f506b 165 SUPERFAMILY SSF116726 69 156 7.85E-16 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_24660 f8c4380cbf0716511c882144d60f506b 165 PIRSF PIRSF005028 1 162 1.0E-51 T 01-11-2018 IPR026278 Potassium/proton antiporter subunit KhtT MLA2C4_24660 f8c4380cbf0716511c882144d60f506b 165 Pfam PF02080 TrkA-C domain 89 158 1.2E-12 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 PRINTS PR00069 Aldo-keto reductase signature 161 190 5.1E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 PRINTS PR00069 Aldo-keto reductase signature 127 144 5.1E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 PRINTS PR00069 Aldo-keto reductase signature 198 222 5.1E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 PRINTS PR00069 Aldo-keto reductase signature 97 115 5.1E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 PRINTS PR00069 Aldo-keto reductase signature 41 65 5.1E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 PIRSF PIRSF000097 3 274 1.3E-91 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 Gene3D G3DSA:3.20.20.100 3 277 3.9E-123 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 Pfam PF00248 Aldo/keto reductase family 30 263 7.7E-52 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_01135 68a632a2a421a27754ef1fc184090e4a 277 SUPERFAMILY SSF51430 9 271 4.85E-95 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_08150 755385f95ca2795ee09266521a7bb1b6 200 TIGRFAM TIGR00648 recU: recombination protein U 29 196 1.2E-77 T 01-11-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 MLA2C4_08150 755385f95ca2795ee09266521a7bb1b6 200 SUPERFAMILY SSF52980 32 198 3.22E-67 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MLA2C4_08150 755385f95ca2795ee09266521a7bb1b6 200 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 200 101.546 T 01-11-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 MLA2C4_08150 755385f95ca2795ee09266521a7bb1b6 200 Pfam PF03838 Recombination protein U 30 195 1.9E-67 T 01-11-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 MLA2C4_08150 755385f95ca2795ee09266521a7bb1b6 200 Gene3D G3DSA:3.40.1350.10 33 200 1.1E-67 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MLA2C4_08150 755385f95ca2795ee09266521a7bb1b6 200 PIRSF PIRSF037785 22 200 2.7E-76 T 01-11-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 MLA2C4_04570 262f5acab85621d5cd438765b5f1800d 192 Gene3D G3DSA:1.10.357.10 1 190 8.7E-54 T 01-11-2018 MLA2C4_04570 262f5acab85621d5cd438765b5f1800d 192 SUPERFAMILY SSF46689 3 62 1.3E-14 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_04570 262f5acab85621d5cd438765b5f1800d 192 SUPERFAMILY SSF48498 77 184 5.34E-13 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_04570 262f5acab85621d5cd438765b5f1800d 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.8E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_04570 262f5acab85621d5cd438765b5f1800d 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.8E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_04570 262f5acab85621d5cd438765b5f1800d 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 48 2.4E-13 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_14475 d35fbee020a6084967791f6204548ab5 477 Pfam PF02687 FtsX-like permease family 342 469 9.1E-13 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 Gene3D G3DSA:2.40.50.140 284 349 3.1E-33 T 01-11-2018 MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 SMART SM00382 29 218 2.4E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 SUPERFAMILY SSF50331 237 365 1.46E-27 T 01-11-2018 IPR008995 Molybdate/tungstate binding, C-terminal MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 Pfam PF00005 ABC transporter 21 162 2.1E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 Gene3D G3DSA:3.40.50.300 1 239 6.8E-73 T 01-11-2018 MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 Pfam PF08402 TOBE domain 281 356 6.3E-6 T 01-11-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 SUPERFAMILY SSF52540 4 243 6.86E-85 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09255 3b717cc03bc602449718a3d9bc224ee1 367 Gene3D G3DSA:2.40.50.100 240 361 3.1E-33 T 01-11-2018 MLA2C4_18995 3ace828bb19fc2b87e3500051dde2d6a 217 Gene3D G3DSA:3.40.50.300 23 216 4.3E-11 T 01-11-2018 MLA2C4_18995 3ace828bb19fc2b87e3500051dde2d6a 217 Pfam PF13521 AAA domain 31 202 1.6E-10 T 01-11-2018 IPR038727 NadR/Ttd14, AAA domain MLA2C4_18995 3ace828bb19fc2b87e3500051dde2d6a 217 SUPERFAMILY SSF52540 27 214 2.03E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 Gene3D G3DSA:2.60.15.10 1 88 1.2E-32 T 01-11-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 130 7.7E-15 T 01-11-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 SUPERFAMILY SSF51344 2 83 3.01E-24 T 01-11-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 129 7.3E-38 T 01-11-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 2.0E-38 T 01-11-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 Gene3D G3DSA:1.20.5.440 89 133 1.5E-16 T 01-11-2018 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 7.5E-30 T 01-11-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.033 T 01-11-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27455 11dade4bef989d1e8015ac8a91736732 133 SUPERFAMILY SSF46604 87 131 5.23E-10 T 01-11-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_16300 d6946f9471fface8970e7d9baf4b7d40 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.6E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_16300 d6946f9471fface8970e7d9baf4b7d40 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.6E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_16300 d6946f9471fface8970e7d9baf4b7d40 205 Pfam PF14278 Transcriptional regulator C-terminal region 99 175 9.4E-22 T 01-11-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type MLA2C4_16300 d6946f9471fface8970e7d9baf4b7d40 205 Gene3D G3DSA:1.10.357.10 7 193 4.3E-53 T 01-11-2018 MLA2C4_16300 d6946f9471fface8970e7d9baf4b7d40 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 1.1E-9 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_16300 d6946f9471fface8970e7d9baf4b7d40 205 SUPERFAMILY SSF46689 8 71 1.44E-16 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 Gene3D G3DSA:3.40.50.10490 45 224 1.3E-79 T 01-11-2018 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 9.4E-27 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 9.4E-27 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 9.4E-27 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 9.4E-27 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 9.4E-27 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 9.4E-27 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 2 436 26.503 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 SUPERFAMILY SSF53697 6 448 2.64E-144 T 01-11-2018 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 Pfam PF00342 Phosphoglucose isomerase 77 297 6.8E-17 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 Pfam PF00342 Phosphoglucose isomerase 332 426 1.0E-4 T 01-11-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 Gene3D G3DSA:3.40.50.10490 1 44 5.9E-18 T 01-11-2018 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 01-11-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 Gene3D G3DSA:3.40.50.10490 225 418 2.8E-83 T 01-11-2018 MLA2C4_25495 15752f75d74c717c21f73a5e485768ec 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 01-11-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_06130 8aad0219007249329281a9b4085cb6d8 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 220 5.7E-58 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_06130 8aad0219007249329281a9b4085cb6d8 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 1.5E-18 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_06130 8aad0219007249329281a9b4085cb6d8 285 PIRSF PIRSF006483 1 285 6.2E-93 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_06130 8aad0219007249329281a9b4085cb6d8 285 Gene3D G3DSA:3.30.70.120 198 272 8.8E-19 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_12170 6e643f7ebba74afea84cc26fad6700dc 99 Gene3D G3DSA:1.10.10.10 4 98 1.4E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_12170 6e643f7ebba74afea84cc26fad6700dc 99 Pfam PF01022 Bacterial regulatory protein, arsR family 26 66 1.4E-11 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_12170 6e643f7ebba74afea84cc26fad6700dc 99 SUPERFAMILY SSF46785 14 86 2.38E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12170 6e643f7ebba74afea84cc26fad6700dc 99 SMART SM00418 19 97 2.8E-20 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 SUPERFAMILY SSF54292 2 111 3.13E-22 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 SUPERFAMILY SSF46548 113 238 2.44E-26 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 117 8.7E-29 T 01-11-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 233 1.2E-40 T 01-11-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 Gene3D G3DSA:3.10.20.30 1 111 1.1E-29 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 Pfam PF13183 4Fe-4S dicluster domain 150 225 4.2E-9 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_23480 f1adeede25b2b3a2ef9baec68f200b34 253 Gene3D G3DSA:1.10.1060.10 113 247 1.2E-28 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 443 2.1E-190 T 01-11-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Gene3D G3DSA:3.30.300.180 1 82 2.8E-31 T 01-11-2018 IPR038454 DnaA, N-terminal domain superfamily MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 SMART SM00760 355 424 2.2E-41 T 01-11-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Pfam PF00308 Bacterial dnaA protein 111 327 3.0E-108 T 01-11-2018 IPR013317 Chromosomal replication initiator protein DnaA MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 SUPERFAMILY SSF52540 111 323 2.35E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Gene3D G3DSA:1.10.1750.10 346 445 3.6E-35 T 01-11-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Pfam PF11638 DnaA N-terminal domain 6 66 2.6E-20 T 01-11-2018 IPR024633 DnaA N-terminal domain MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 358 424 5.1E-30 T 01-11-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 01-11-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 01-11-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 01-11-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 01-11-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 01-11-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 SUPERFAMILY SSF48295 342 446 1.33E-36 T 01-11-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Gene3D G3DSA:3.40.50.300 96 275 9.5E-56 T 01-11-2018 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 SMART SM00382 143 271 2.4E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.258 T 01-11-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 01-11-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MLA2C4_00005 352e5dc3b9f7093a45a4094f0a3f326e 446 Gene3D G3DSA:1.10.8.60 277 345 3.2E-30 T 01-11-2018 MLA2C4_08525 7b15e9b1f3d99f53a9d39fb34b25bfbc 122 Pfam PF00072 Response regulator receiver domain 5 116 3.6E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_08525 7b15e9b1f3d99f53a9d39fb34b25bfbc 122 Gene3D G3DSA:3.40.50.12740 4 122 1.2E-37 T 01-11-2018 MLA2C4_08525 7b15e9b1f3d99f53a9d39fb34b25bfbc 122 SUPERFAMILY SSF52172 4 120 6.97E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_08525 7b15e9b1f3d99f53a9d39fb34b25bfbc 122 SMART SM00448 3 116 8.1E-34 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09050 38312e8b91cbe217d5d550a8ea058956 415 Pfam PF04286 Protein of unknown function (DUF445) 40 415 5.6E-86 T 01-11-2018 IPR007383 Protein of unknown function DUF445 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 SUPERFAMILY SSF55811 236 358 1.82E-24 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 Gene3D G3DSA:1.10.1670.10 17 220 5.8E-89 T 01-11-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 Gene3D G3DSA:1.10.340.30 28 139 5.8E-89 T 01-11-2018 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 13 283 1.7E-109 T 01-11-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 SMART SM00525 198 218 0.0011 T 01-11-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 176 3.2E-21 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 Pfam PF14815 NUDIX domain 243 356 1.2E-18 T 01-11-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 Pfam PF00633 Helix-hairpin-helix motif 107 135 1.6E-5 T 01-11-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 SUPERFAMILY SSF48150 11 229 1.27E-75 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 199 215 - T 01-11-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 Gene3D G3DSA:3.90.79.10 237 363 1.2E-26 T 01-11-2018 MLA2C4_02710 a304d153b1dbc18e5e9acf7c6a1099ae 365 SMART SM00478 46 197 2.4E-56 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 Gene3D G3DSA:1.10.287.950 269 578 9.0E-55 T 01-11-2018 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 3.4E-16 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 3.4E-16 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 327 356 3.4E-16 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 13 38 3.4E-16 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 SMART SM00304 519 575 24.0 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 SMART SM00304 223 274 8.0E-6 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 SMART SM00283 303 578 2.2E-45 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 351 529 6.8E-34 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_02295 35c959e865ddc79e2d50467185fd9799 579 SUPERFAMILY SSF58104 250 578 1.31E-55 T 01-11-2018 MLA2C4_17415 80a1bcbcff0f4736c2bf95a2d6cc025f 385 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 263 336 1.4E-10 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_17415 80a1bcbcff0f4736c2bf95a2d6cc025f 385 Pfam PF12323 Helix-turn-helix domain 1 46 2.5E-16 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_17415 80a1bcbcff0f4736c2bf95a2d6cc025f 385 Pfam PF01385 Probable transposase 167 296 5.2E-14 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_17415 80a1bcbcff0f4736c2bf95a2d6cc025f 385 Pfam PF07282 Putative transposase DNA-binding domain 309 377 6.1E-21 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 150 202 1.2E-5 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 349 2.8E-10 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 134 156 2.3E-22 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 288 299 2.3E-22 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 68 82 2.3E-22 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 178 198 2.3E-22 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 Gene3D G3DSA:3.40.50.10860 12 345 5.9E-153 T 01-11-2018 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 17 132 1.2E-26 T 01-11-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 SMART SM00839 146 353 1.6E-69 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 SUPERFAMILY SSF53223 6 145 8.64E-48 T 01-11-2018 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 Gene3D G3DSA:3.40.50.720 136 338 5.9E-153 T 01-11-2018 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 PIRSF PIRSF000188 3 355 2.2E-166 T 01-11-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 SUPERFAMILY SSF51735 143 349 1.96E-58 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21780 8181fcf0f08c1761532ce39b2a836cec 366 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 76 89 - T 01-11-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 SUPERFAMILY SSF46894 137 231 2.21E-20 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 SUPERFAMILY SSF52172 13 170 1.42E-43 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 SMART SM00862 155 230 1.9E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 2.7E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 SMART SM00448 12 122 1.5E-42 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 Pfam PF00072 Response regulator receiver domain 14 122 1.6E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 Gene3D G3DSA:3.40.50.2300 6 135 2.6E-39 T 01-11-2018 MLA2C4_09935 49bdf509078fd878300acb0a4ef98cee 234 Gene3D G3DSA:1.10.10.10 136 234 9.8E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08450 5800293ac5c1e3e929c48fe7ad1103fe 244 PIRSF PIRSF005426 1 244 2.7E-91 T 01-11-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 MLA2C4_08450 5800293ac5c1e3e929c48fe7ad1103fe 244 Pfam PF00881 Nitroreductase family 10 161 6.3E-20 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_08450 5800293ac5c1e3e929c48fe7ad1103fe 244 Gene3D G3DSA:3.40.109.10 1 244 2.0E-74 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_08450 5800293ac5c1e3e929c48fe7ad1103fe 244 SUPERFAMILY SSF55469 1 243 7.98E-72 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 SUPERFAMILY SSF52335 1 127 5.1E-52 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 PIRSF PIRSF006614 1 131 1.0E-61 T 01-11-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 Pfam PF02142 MGS-like domain 15 107 4.2E-18 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 34.094 T 01-11-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 120 8.4E-58 T 01-11-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 SMART SM00851 14 107 8.4E-24 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 Gene3D G3DSA:3.40.50.1380 1 131 3.2E-56 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MLA2C4_08065 4abdd44cc15868725c96463d248f8285 131 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 61 - T 01-11-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 Pfam PF01641 SelR domain 183 301 3.6E-48 T 01-11-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 179 310 1.8E-64 T 01-11-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 Pfam PF01625 Peptide methionine sulfoxide reductase 10 159 2.7E-59 T 01-11-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 159 1.5E-60 T 01-11-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 Gene3D G3DSA:3.30.1060.10 1 166 1.6E-63 T 01-11-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 7 166 35.7 T 01-11-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 172 302 37.841 T 01-11-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 SUPERFAMILY SSF55068 3 171 7.59E-71 T 01-11-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 SUPERFAMILY SSF51316 178 317 8.89E-60 T 01-11-2018 IPR011057 Mss4-like superfamily MLA2C4_28160 a601722a7fccc8af6f790151a0b1564d 321 Gene3D G3DSA:2.170.150.20 177 319 6.7E-59 T 01-11-2018 MLA2C4_00355 8b7a62049744f175c17cadf8d50e1427 823 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 43 805 7.7E-254 T 01-11-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_00355 8b7a62049744f175c17cadf8d50e1427 823 SMART SM00332 602 803 2.9E-4 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_00355 8b7a62049744f175c17cadf8d50e1427 823 SMART SM00331 593 805 2.2E-50 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_00355 8b7a62049744f175c17cadf8d50e1427 823 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 620 805 5.2E-36 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_00355 8b7a62049744f175c17cadf8d50e1427 823 SUPERFAMILY SSF81606 594 806 1.44E-21 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_00355 8b7a62049744f175c17cadf8d50e1427 823 Gene3D G3DSA:3.60.40.10 587 823 9.3E-52 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SUPERFAMILY SSF47384 358 423 6.87E-13 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Pfam PF00989 PAS fold 113 198 2.3E-9 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 571 1.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 1.1E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Gene3D G3DSA:3.30.450.20 110 236 1.8E-14 T 01-11-2018 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SUPERFAMILY SSF55874 416 574 2.49E-40 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 572 7.2E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Pfam PF08448 PAS fold 245 348 7.2E-17 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SUPERFAMILY SSF55785 224 345 3.89E-14 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SMART SM00091 113 182 4.5E-6 T 01-11-2018 IPR000014 PAS domain MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SMART SM00091 239 305 1.1 T 01-11-2018 IPR000014 PAS domain MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SMART SM00387 467 574 3.2E-32 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Gene3D G3DSA:1.10.287.130 365 421 4.7E-16 T 01-11-2018 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Gene3D G3DSA:3.30.565.10 424 583 5.7E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SMART SM00388 362 425 2.4E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 SUPERFAMILY SSF55785 110 225 6.46E-14 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 423 1.5E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 Gene3D G3DSA:3.30.450.20 237 358 1.1E-15 T 01-11-2018 MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 240 353 2.5E-6 T 01-11-2018 IPR000014 PAS domain MLA2C4_14075 eaa056bab40a5887d58b1dc2336f7855 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 110 234 9.0E-12 T 01-11-2018 IPR000014 PAS domain MLA2C4_26020 d60767be17878e1b660490f362803a13 185 Pfam PF13305 WHG domain 85 157 1.6E-11 T 01-11-2018 IPR025996 WHG domain MLA2C4_26020 d60767be17878e1b660490f362803a13 185 SUPERFAMILY SSF48498 80 180 3.11E-25 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_26020 d60767be17878e1b660490f362803a13 185 Gene3D G3DSA:1.10.357.10 51 181 3.6E-35 T 01-11-2018 MLA2C4_26020 d60767be17878e1b660490f362803a13 185 Gene3D G3DSA:1.10.10.60 1 50 3.6E-24 T 01-11-2018 MLA2C4_26020 d60767be17878e1b660490f362803a13 185 SUPERFAMILY SSF46689 6 74 9.75E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 332 2.0E-41 T 01-11-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 3.2E-34 T 01-11-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 3.0E-118 T 01-11-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 Gene3D G3DSA:1.10.8.60 183 257 4.3E-31 T 01-11-2018 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 SUPERFAMILY SSF52540 21 253 1.0E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 175.537 T 01-11-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 6.0E-149 T 01-11-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 Gene3D G3DSA:1.10.10.10 258 333 7.8E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 SUPERFAMILY SSF46785 257 331 5.71E-26 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 SMART SM00382 52 183 5.3E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23045 89606a681ee27dd9c1dbde153709d921 333 Gene3D G3DSA:3.40.50.300 21 182 3.1E-41 T 01-11-2018 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 SUPERFAMILY SSF55136 135 294 1.36E-35 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 SMART SM00871 136 294 6.8E-34 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 Pfam PF12833 Helix-turn-helix domain 34 113 1.3E-19 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 65 108 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 SMART SM00342 28 112 1.2E-25 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 81 96 4.4E-8 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 96 112 4.4E-8 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 Gene3D G3DSA:3.20.80.10 137 295 1.7E-40 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 SUPERFAMILY SSF46689 65 115 1.39E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 Pfam PF14526 Integron-associated effector binding protein 139 293 7.4E-31 T 01-11-2018 IPR029441 Integron-associated effector binding protein MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 Gene3D G3DSA:1.10.10.60 62 120 6.3E-18 T 01-11-2018 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 Gene3D G3DSA:1.10.10.60 3 61 6.7E-16 T 01-11-2018 MLA2C4_16010 6415cefcddf03ee77699f8d4e2be274d 296 SUPERFAMILY SSF46689 12 62 5.73E-11 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 TIGRFAM TIGR00235 udk: uridine kinase 2 207 5.3E-91 T 01-11-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 SUPERFAMILY SSF52540 4 198 2.79E-50 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 Hamap MF_00551 Uridine kinase [udk]. 3 207 41.017 T 01-11-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 Gene3D G3DSA:3.40.50.300 2 211 9.1E-66 T 01-11-2018 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 8 193 1.9E-40 T 01-11-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 PRINTS PR00988 Uridine kinase signature 36 47 1.4E-36 T 01-11-2018 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 PRINTS PR00988 Uridine kinase signature 173 186 1.4E-36 T 01-11-2018 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 PRINTS PR00988 Uridine kinase signature 6 23 1.4E-36 T 01-11-2018 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 PRINTS PR00988 Uridine kinase signature 137 147 1.4E-36 T 01-11-2018 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 PRINTS PR00988 Uridine kinase signature 81 96 1.4E-36 T 01-11-2018 MLA2C4_22850 d22139416c49f7bb3c7772aad3fdbb82 212 PRINTS PR00988 Uridine kinase signature 151 162 1.4E-36 T 01-11-2018 MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 SUPERFAMILY SSF88659 101 166 1.72E-10 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 SUPERFAMILY SSF88946 22 81 3.1E-9 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 Pfam PF08281 Sigma-70, region 4 109 160 1.5E-12 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 Pfam PF04542 Sigma-70 region 2 24 83 1.4E-6 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 Gene3D G3DSA:1.10.10.10 104 165 2.0E-11 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 Gene3D G3DSA:1.10.1740.10 14 86 2.7E-8 T 01-11-2018 MLA2C4_14775 20949eb24b24e05f3ad2713ac5c1a57a 228 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 161 5.6E-16 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_06710 89ebec5f170faae83aab918319c13bfc 168 TIGRFAM TIGR00608 radc: DNA repair protein RadC 42 167 3.1E-40 T 01-11-2018 IPR001405 Uncharacterised protein family UPF0758 MLA2C4_06710 89ebec5f170faae83aab918319c13bfc 168 Pfam PF04002 RadC-like JAB domain 48 166 8.4E-41 T 01-11-2018 IPR025657 RadC-like JAB domain MLA2C4_06710 89ebec5f170faae83aab918319c13bfc 168 Gene3D G3DSA:3.40.140.10 43 168 7.5E-44 T 01-11-2018 MLA2C4_06970 8abcca2ddc3c8257e02ce85d23608451 147 SUPERFAMILY SSF54637 15 144 3.32E-40 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_06970 8abcca2ddc3c8257e02ce85d23608451 147 Pfam PF01575 MaoC like domain 25 126 1.9E-25 T 01-11-2018 IPR002539 MaoC-like dehydratase domain MLA2C4_06970 8abcca2ddc3c8257e02ce85d23608451 147 Gene3D G3DSA:3.10.129.10 5 147 1.6E-46 T 01-11-2018 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Pfam PF00175 Oxidoreductase NAD-binding domain 916 1026 1.8E-14 T 01-11-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 01-11-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Pfam PF00258 Flavodoxin 498 630 2.9E-27 T 01-11-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PIRSF PIRSF000209 2 1065 0.0 T 01-11-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 SUPERFAMILY SSF48264 5 456 2.49E-111 T 01-11-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 SUPERFAMILY SSF52343 903 1062 6.55E-46 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Gene3D G3DSA:2.40.30.10 681 893 2.3E-69 T 01-11-2018 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Pfam PF00667 FAD binding domain 677 883 2.2E-40 T 01-11-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Gene3D G3DSA:3.40.50.80 904 1064 5.0E-56 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Gene3D G3DSA:1.10.630.10 4 472 4.6E-172 T 01-11-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 SUPERFAMILY SSF52218 492 648 7.12E-42 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 878 887 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 944 953 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1011 1019 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 843 850 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 988 1004 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 957 968 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 709 719 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 915 934 1.8E-30 T 01-11-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 SUPERFAMILY SSF63380 676 899 1.58E-63 T 01-11-2018 IPR017938 Riboflavin synthase-like beta-barrel MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00369 Flavodoxin signature 575 585 5.1E-9 T 01-11-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00369 Flavodoxin signature 600 619 5.1E-9 T 01-11-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 PRINTS PR00369 Flavodoxin signature 497 510 5.1E-9 T 01-11-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Gene3D G3DSA:1.20.990.10 719 841 2.3E-69 T 01-11-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Pfam PF00067 Cytochrome P450 9 450 3.0E-88 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_16855 ea0710eb0bce036ee263fda3e2de73f9 1065 Gene3D G3DSA:3.40.50.360 494 644 3.0E-45 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Pfam PF02824 TGS domain 394 453 2.7E-20 T 01-11-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 SUPERFAMILY SSF81271 381 453 7.36E-22 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 SUPERFAMILY SSF55021 648 726 8.7E-11 T 01-11-2018 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 724 2.9E-259 T 01-11-2018 IPR004811 RelA/SpoT family GO:0015969 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 SMART SM00954 240 350 4.5E-69 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 SUPERFAMILY SSF81301 185 398 1.8E-67 T 01-11-2018 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Pfam PF13291 ACT domain 649 724 1.4E-20 T 01-11-2018 IPR002912 ACT domain MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 SUPERFAMILY SSF109604 10 196 2.86E-77 T 01-11-2018 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 SMART SM00471 46 158 1.3E-8 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 1.3E-39 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Gene3D G3DSA:3.10.20.30 387 459 6.7E-31 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Pfam PF13328 HD domain 31 180 1.0E-52 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Gene3D G3DSA:1.10.3210.10 1 196 9.5E-89 T 01-11-2018 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Gene3D G3DSA:3.30.460.10 198 330 2.1E-54 T 01-11-2018 MLA2C4_22980 57f54d3327defea1a29790e71646c492 727 Gene3D G3DSA:3.30.70.260 648 727 1.3E-16 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 SUPERFAMILY SSF51905 4 367 6.76E-55 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 01-11-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 SUPERFAMILY SSF55424 336 458 1.19E-37 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 5.1E-33 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 Gene3D G3DSA:3.50.50.60 146 265 3.0E-112 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PIRSF PIRSF000350 1 454 3.9E-87 T 01-11-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 Gene3D G3DSA:3.30.390.30 339 459 3.2E-40 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 Gene3D G3DSA:3.50.50.60 5 325 3.0E-112 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 7.8E-67 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.8E-37 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 1.8E-37 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.8E-37 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.8E-37 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 1.8E-37 T 01-11-2018 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 458 7.0E-169 T 01-11-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MLA2C4_14685 d53bce51fd6eed4f24dbf942d04bfa3a 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 321 2.0E-66 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 SMART SM00766 466 591 2.0E-21 T 01-11-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 SUPERFAMILY SSF56731 118 425 5.36E-105 T 01-11-2018 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Pfam PF10410 DnaB-helicase binding domain of primase 371 420 2.7E-6 T 01-11-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 PIRSF PIRSF002811 2 598 5.1E-187 T 01-11-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Gene3D G3DSA:3.90.580.10 1 102 4.5E-42 T 01-11-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Pfam PF13155 Toprim-like 265 349 8.1E-20 T 01-11-2018 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 SMART SM00400 36 90 3.7E-34 T 01-11-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Pfam PF01807 CHC2 zinc finger 6 98 1.0E-37 T 01-11-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 SMART SM00493 262 333 1.2E-18 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Gene3D G3DSA:3.90.980.10 114 243 5.2E-47 T 01-11-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 5.0E-152 T 01-11-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Gene3D G3DSA:3.40.1360.10 244 367 9.5E-41 T 01-11-2018 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Hamap MF_00974 DNA primase [dnaG]. 4 589 29.235 T 01-11-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Gene3D G3DSA:1.10.860.10 463 558 2.3E-21 T 01-11-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 SUPERFAMILY SSF57783 4 97 6.29E-36 T 01-11-2018 MLA2C4_22435 454a0da454b93edfd66c4c3aa9a089b6 598 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 8.8E-44 T 01-11-2018 IPR013264 DNA primase, catalytic core, N-terminal MLA2C4_07180 cea3c6f0bef318c051b07ba51d4c1a92 322 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 92 108 - T 01-11-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MLA2C4_07180 cea3c6f0bef318c051b07ba51d4c1a92 322 SUPERFAMILY SSF47240 2 318 1.03E-90 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_07180 cea3c6f0bef318c051b07ba51d4c1a92 322 Gene3D G3DSA:1.10.620.20 1 290 1.4E-111 T 01-11-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MLA2C4_07180 cea3c6f0bef318c051b07ba51d4c1a92 322 Pfam PF00268 Ribonucleotide reductase, small chain 4 281 5.2E-79 T 01-11-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MLA2C4_07180 cea3c6f0bef318c051b07ba51d4c1a92 322 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 1 320 1.6E-142 T 01-11-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MLA2C4_07180 cea3c6f0bef318c051b07ba51d4c1a92 322 PIRSF PIRSF000355 1 316 2.5E-84 T 01-11-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MLA2C4_06170 ed2e5116688927e6ef2b06c937ff2821 290 SUPERFAMILY SSF51735 12 230 1.53E-21 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_06170 ed2e5116688927e6ef2b06c937ff2821 290 Gene3D G3DSA:3.40.50.720 9 289 1.3E-20 T 01-11-2018 MLA2C4_06170 ed2e5116688927e6ef2b06c937ff2821 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 212 1.2E-5 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_18980 bbf2678bffd67a2124a113db52c0923b 146 Gene3D G3DSA:3.40.1510.10 1 146 1.8E-62 T 01-11-2018 IPR036482 Hut operon regulatory protein HutP superfamily MLA2C4_18980 bbf2678bffd67a2124a113db52c0923b 146 Pfam PF09021 HutP 9 144 4.2E-38 T 01-11-2018 IPR015111 Hut operon regulatory protein HutP MLA2C4_18980 bbf2678bffd67a2124a113db52c0923b 146 SUPERFAMILY SSF111064 7 146 2.09E-62 T 01-11-2018 IPR036482 Hut operon regulatory protein HutP superfamily MLA2C4_18980 bbf2678bffd67a2124a113db52c0923b 146 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 146 45.408 T 01-11-2018 IPR023552 Hut operon regulatory protein HutP, bacillales MLA2C4_27735 457487eb23d6dc64f04d6bd3c6e63283 466 Pfam PF04389 Peptidase family M28 246 446 6.4E-39 T 01-11-2018 IPR007484 Peptidase M28 MLA2C4_27735 457487eb23d6dc64f04d6bd3c6e63283 466 SUPERFAMILY SSF52025 127 228 1.96E-9 T 01-11-2018 MLA2C4_27735 457487eb23d6dc64f04d6bd3c6e63283 466 Gene3D G3DSA:3.40.630.10 64 443 1.5E-97 T 01-11-2018 MLA2C4_27735 457487eb23d6dc64f04d6bd3c6e63283 466 Pfam PF02225 PA domain 130 219 1.4E-9 T 01-11-2018 IPR003137 PA domain MLA2C4_27735 457487eb23d6dc64f04d6bd3c6e63283 466 Gene3D G3DSA:3.50.30.30 105 236 1.5E-97 T 01-11-2018 MLA2C4_27735 457487eb23d6dc64f04d6bd3c6e63283 466 SUPERFAMILY SSF53187 39 452 6.29E-55 T 01-11-2018 MLA2C4_00550 29b1bcf4d92fa6f1c81de0a46633316b 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.293 T 01-11-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MLA2C4_00550 29b1bcf4d92fa6f1c81de0a46633316b 158 Pfam PF02542 YgbB family 2 156 2.2E-67 T 01-11-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MLA2C4_00550 29b1bcf4d92fa6f1c81de0a46633316b 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 1.0E-73 T 01-11-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MLA2C4_00550 29b1bcf4d92fa6f1c81de0a46633316b 158 Gene3D G3DSA:3.30.1330.50 1 158 6.4E-70 T 01-11-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MLA2C4_00550 29b1bcf4d92fa6f1c81de0a46633316b 158 SUPERFAMILY SSF69765 1 157 1.83E-67 T 01-11-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MLA2C4_00550 29b1bcf4d92fa6f1c81de0a46633316b 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 01-11-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 PRINTS PR00956 Flagellar motor switch protein FliN signature 495 511 1.3E-7 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 PRINTS PR00956 Flagellar motor switch protein FliN signature 524 539 1.3E-7 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 PRINTS PR00956 Flagellar motor switch protein FliN signature 511 524 1.3E-7 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 PRINTS PR00956 Flagellar motor switch protein FliN signature 478 494 1.3E-7 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Gene3D G3DSA:3.40.1550.10 20 218 3.6E-44 T 01-11-2018 IPR028976 CheC-like superfamily MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Gene3D G3DSA:3.40.1550.10 242 437 4.1E-45 T 01-11-2018 IPR028976 CheC-like superfamily MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Pfam PF04509 CheC-like family 26 60 4.7E-11 T 01-11-2018 IPR007597 CheC-like protein GO:0016787 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Pfam PF04509 CheC-like family 345 380 3.5E-13 T 01-11-2018 IPR007597 CheC-like protein GO:0016787 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Pfam PF04509 CheC-like family 122 158 5.8E-15 T 01-11-2018 IPR007597 CheC-like protein GO:0016787 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Pfam PF04509 CheC-like family 247 282 9.4E-11 T 01-11-2018 IPR007597 CheC-like protein GO:0016787 MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 SUPERFAMILY SSF101801 476 546 2.09E-15 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 SUPERFAMILY SSF103039 20 211 4.05E-45 T 01-11-2018 IPR028976 CheC-like superfamily MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 SUPERFAMILY SSF103039 242 433 2.22E-45 T 01-11-2018 IPR028976 CheC-like superfamily MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Gene3D G3DSA:2.30.330.10 466 548 4.8E-18 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_08535 49a65378068fa32c6611768b0b0a0892 548 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 479 546 4.7E-17 T 01-11-2018 IPR001543 Surface presentation of antigen (SpoA) MLA2C4_11485 46b6ddde6e668f16337c63e759e7fb3b 281 SUPERFAMILY SSF55729 129 279 1.01E-19 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_11485 46b6ddde6e668f16337c63e759e7fb3b 281 Pfam PF13527 Acetyltransferase (GNAT) domain 130 241 3.4E-9 T 01-11-2018 MLA2C4_11485 46b6ddde6e668f16337c63e759e7fb3b 281 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 18 279 1.0E-103 T 01-11-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 MLA2C4_11485 46b6ddde6e668f16337c63e759e7fb3b 281 Gene3D G3DSA:3.40.630.30 121 275 7.5E-15 T 01-11-2018 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 Gene3D G3DSA:3.50.50.60 3 111 2.1E-24 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 Gene3D G3DSA:3.50.50.60 285 342 2.0E-11 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 SUPERFAMILY SSF51905 1 352 2.86E-37 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.7E-9 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 318 336 1.7E-9 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.0E-15 T 01-11-2018 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 1.0E-15 T 01-11-2018 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.0E-15 T 01-11-2018 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 330 1.0E-15 T 01-11-2018 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 342 5.2E-16 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 Gene3D G3DSA:3.50.50.60 112 169 2.1E-24 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_15015 41a82702c8ec05b7ddf6e34df777f5b6 411 Gene3D G3DSA:3.50.50.60 232 284 2.0E-11 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 431 2.9E-236 T 01-11-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 37.211 T 01-11-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 Pfam PF01134 Glucose inhibited division protein A 6 368 6.1E-117 T 01-11-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 SUPERFAMILY SSF51905 7 367 4.43E-29 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 Gene3D G3DSA:3.50.50.60 290 434 5.0E-54 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 Gene3D G3DSA:3.50.50.60 3 178 5.4E-57 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20030 1ac5d249df447ea2efe28992d98f3c34 434 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 01-11-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MLA2C4_10950 aa936f7bdfcab536cc361386c51e09e1 243 Pfam PF12811 Bax inhibitor 1 like 5 240 3.4E-71 T 01-11-2018 IPR010539 Protein of unknown function UCP009160 MLA2C4_10950 aa936f7bdfcab536cc361386c51e09e1 243 PIRSF PIRSF009160 1 243 5.2E-92 T 01-11-2018 IPR010539 Protein of unknown function UCP009160 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 Pfam PF00512 His Kinase A (phospho-acceptor) domain 405 469 6.4E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 515 622 7.4E-18 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 Gene3D G3DSA:1.10.287.130 396 474 3.3E-19 T 01-11-2018 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 SMART SM00304 337 389 1.2E-9 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 Gene3D G3DSA:3.30.565.10 475 624 1.5E-34 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 SUPERFAMILY SSF55874 459 622 2.36E-35 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 SUPERFAMILY SSF158472 338 388 4.05E-9 T 01-11-2018 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 SMART SM00388 404 469 1.5E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 Pfam PF00672 HAMP domain 338 385 5.9E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 Gene3D G3DSA:1.20.1480.50 298 395 7.3E-14 T 01-11-2018 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 SMART SM00387 513 624 8.7E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 578 1.3E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 621 1.3E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 564 1.3E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 603 1.3E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25045 7b33563b59b043c319b1c4a3cc640b0f 624 SUPERFAMILY SSF47384 390 469 3.34E-15 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 Gene3D G3DSA:3.40.50.1860 96 208 6.8E-102 T 01-11-2018 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 SUPERFAMILY SSF53681 112 264 1.47E-40 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 SUPERFAMILY SSF53681 6 108 9.81E-37 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 216 5.6E-44 T 01-11-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 01-11-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 255 1.1E-89 T 01-11-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 Hamap MF_00258 Glutamate racemase [murI]. 5 257 40.919 T 01-11-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 Gene3D G3DSA:3.40.50.1860 7 256 6.8E-102 T 01-11-2018 MLA2C4_23380 fa590fb52f29add2e4695d6e629d87e0 269 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 01-11-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_21550 26131cd02bfc742042ca0c406eb2290b 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 239 248 - T 01-11-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MLA2C4_21550 26131cd02bfc742042ca0c406eb2290b 395 Pfam PF00155 Aminotransferase class I and II 42 384 4.9E-68 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_21550 26131cd02bfc742042ca0c406eb2290b 395 Gene3D G3DSA:3.90.1150.10 39 381 2.5E-131 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_21550 26131cd02bfc742042ca0c406eb2290b 395 Gene3D G3DSA:3.40.640.10 57 292 2.5E-131 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_21550 26131cd02bfc742042ca0c406eb2290b 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 384 2.4E-138 T 01-11-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MLA2C4_21550 26131cd02bfc742042ca0c406eb2290b 395 SUPERFAMILY SSF53383 5 390 2.89E-109 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_09980 af78c3f9e808d652e140b5c30a8a9167 223 Gene3D G3DSA:3.40.50.150 2 223 5.5E-82 T 01-11-2018 MLA2C4_09980 af78c3f9e808d652e140b5c30a8a9167 223 SUPERFAMILY SSF53335 10 222 3.35E-41 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_09980 af78c3f9e808d652e140b5c30a8a9167 223 Pfam PF01596 O-methyltransferase 23 205 1.8E-44 T 01-11-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Pfam PF05192 MutS domain III 261 551 6.4E-44 T 01-11-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 SUPERFAMILY SSF52540 559 791 9.58E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Pfam PF01624 MutS domain I 5 115 1.4E-46 T 01-11-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Pfam PF05188 MutS domain II 125 243 9.4E-7 T 01-11-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Gene3D G3DSA:3.30.420.110 124 251 2.3E-11 T 01-11-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 PIRSF PIRSF037677 149 838 6.7E-129 T 01-11-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 PIRSF PIRSF037677 1 177 3.1E-30 T 01-11-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 681 697 - T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 887 0.0 T 01-11-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 881 25.504 T 01-11-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Gene3D G3DSA:3.40.50.300 560 871 1.6E-101 T 01-11-2018 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Pfam PF00488 MutS domain V 604 790 4.3E-84 T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Gene3D G3DSA:1.10.1420.10 256 551 6.1E-100 T 01-11-2018 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 SUPERFAMILY SSF55271 2 112 2.35E-42 T 01-11-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 SMART SM00533 274 583 7.0E-99 T 01-11-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 SUPERFAMILY SSF53150 114 270 1.44E-28 T 01-11-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 SMART SM00534 600 787 1.8E-117 T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Pfam PF05190 MutS family domain IV 419 510 9.7E-27 T 01-11-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 SUPERFAMILY SSF48334 257 556 1.7E-86 T 01-11-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Gene3D G3DSA:1.10.1420.10 391 527 6.1E-100 T 01-11-2018 MLA2C4_19710 3de419fbe7111da7a13ab7f84c0836e6 892 Gene3D G3DSA:3.40.1170.10 1 117 3.1E-48 T 01-11-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 SUPERFAMILY SSF103473 13 445 3.79E-37 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 156 168 - T 01-11-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 Gene3D G3DSA:1.20.1250.20 4 223 1.5E-68 T 01-11-2018 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 Gene3D G3DSA:1.20.1250.20 224 449 9.0E-56 T 01-11-2018 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 225 448 1.8E-42 T 01-11-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 212 1.5E-53 T 01-11-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 Pfam PF00854 POT family 224 416 5.8E-34 T 01-11-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MLA2C4_03235 783f740df60aea6c6273edbbe29bcf92 449 Pfam PF00854 POT family 94 201 4.3E-24 T 01-11-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MLA2C4_18645 c1b85eaa5d10cd5dd1c06501b7c6f36c 206 SUPERFAMILY SSF46689 15 94 6.16E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_18645 c1b85eaa5d10cd5dd1c06501b7c6f36c 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 70 6.7E-16 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_18645 c1b85eaa5d10cd5dd1c06501b7c6f36c 206 Gene3D G3DSA:1.10.357.10 11 202 1.1E-27 T 01-11-2018 MLA2C4_18645 c1b85eaa5d10cd5dd1c06501b7c6f36c 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.1E-9 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_18645 c1b85eaa5d10cd5dd1c06501b7c6f36c 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.1E-9 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_14955 21baa8f67f24cf53bc55ff92ed444a09 214 Gene3D G3DSA:1.10.3210.10 10 210 2.1E-7 T 01-11-2018 MLA2C4_14955 21baa8f67f24cf53bc55ff92ed444a09 214 SMART SM00471 21 161 6.6E-6 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_14955 21baa8f67f24cf53bc55ff92ed444a09 214 SUPERFAMILY SSF109604 11 150 4.11E-14 T 01-11-2018 MLA2C4_14955 21baa8f67f24cf53bc55ff92ed444a09 214 Pfam PF01966 HD domain 26 149 5.5E-7 T 01-11-2018 IPR006674 HD domain MLA2C4_12035 f90190c3183e3b76314365ea367fb23f 370 Pfam PF12323 Helix-turn-helix domain 1 48 2.1E-22 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_12035 f90190c3183e3b76314365ea367fb23f 370 Pfam PF01385 Probable transposase 168 280 1.3E-19 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_12035 f90190c3183e3b76314365ea367fb23f 370 Pfam PF07282 Putative transposase DNA-binding domain 294 361 1.3E-17 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_04515 32f375505d318e6e4dff88b5c56550ac 357 Gene3D G3DSA:3.20.20.70 1 236 2.7E-85 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_04515 32f375505d318e6e4dff88b5c56550ac 357 SUPERFAMILY SSF50891 242 350 6.45E-33 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_04515 32f375505d318e6e4dff88b5c56550ac 357 SUPERFAMILY SSF51445 1 234 1.9E-76 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_04515 32f375505d318e6e4dff88b5c56550ac 357 Pfam PF05913 Bacterial protein of unknown function (DUF871) 1 349 3.6E-120 T 01-11-2018 IPR008589 Protein of unknown function DUF871, prokaryotic MLA2C4_04515 32f375505d318e6e4dff88b5c56550ac 357 Gene3D G3DSA:2.40.100.10 243 356 4.7E-39 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_01910 f7bee6ce507a5eb488a8d1163f557d9c 485 ProSitePatterns PS00571 Amidases signature. 151 182 - T 01-11-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MLA2C4_01910 f7bee6ce507a5eb488a8d1163f557d9c 485 Pfam PF01425 Amidase 24 465 2.2E-162 T 01-11-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_01910 f7bee6ce507a5eb488a8d1163f557d9c 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 98.125 T 01-11-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_01910 f7bee6ce507a5eb488a8d1163f557d9c 485 SUPERFAMILY SSF75304 1 480 2.22E-167 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_01910 f7bee6ce507a5eb488a8d1163f557d9c 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.3E-203 T 01-11-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_01910 f7bee6ce507a5eb488a8d1163f557d9c 485 Gene3D G3DSA:3.90.1300.10 2 485 6.5E-200 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SMART SM00052 437 682 3.5E-114 T 01-11-2018 IPR001633 EAL domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 425 6.9E-27 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SUPERFAMILY SSF141868 442 688 1.02E-84 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SMART SM00091 19 88 30.0 T 01-11-2018 IPR000014 PAS domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SMART SM00091 147 213 5.2E-9 T 01-11-2018 IPR000014 PAS domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Gene3D G3DSA:3.30.70.270 266 439 1.5E-41 T 01-11-2018 MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SUPERFAMILY SSF55785 152 260 1.15E-17 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Pfam PF00563 EAL domain 443 677 8.9E-71 T 01-11-2018 IPR001633 EAL domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Gene3D G3DSA:3.20.20.450 440 689 2.1E-94 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Gene3D G3DSA:3.30.450.20 21 145 2.0E-13 T 01-11-2018 MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SMART SM00267 259 427 1.6E-40 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Pfam PF08448 PAS fold 26 135 8.8E-22 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Pfam PF08448 PAS fold 157 260 6.2E-10 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SUPERFAMILY SSF55073 276 427 6.51E-36 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Gene3D G3DSA:3.30.450.20 146 261 3.7E-17 T 01-11-2018 MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 422 1.5E-35 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 260 4.4E-18 T 01-11-2018 IPR000014 PAS domain MLA2C4_02945 56d5556b2561f75af0edd554ef8948c2 689 SUPERFAMILY SSF55785 24 135 6.98E-8 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 SUPERFAMILY SSF55979 1 127 1.17E-23 T 01-11-2018 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 252 9.1E-38 T 01-11-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 SMART SM00480 17 374 4.3E-169 T 01-11-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 PIRSF PIRSF000804 1 379 3.9E-117 T 01-11-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 Gene3D G3DSA:3.70.10.10 145 376 3.4E-135 T 01-11-2018 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 Gene3D G3DSA:3.10.150.10 1 251 3.4E-135 T 01-11-2018 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 1.0E-36 T 01-11-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 SUPERFAMILY SSF55979 133 252 1.14E-26 T 01-11-2018 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 255 377 6.5E-38 T 01-11-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 378 4.0E-125 T 01-11-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MLA2C4_00010 df4d2f35ed91349fb0683ed00b0fd49a 379 SUPERFAMILY SSF55979 255 378 2.13E-32 T 01-11-2018 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 199 219 6.4E-8 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 266 284 6.4E-8 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 Pfam PF16360 GTP-binding GTPase Middle Region 113 191 1.5E-30 T 01-11-2018 IPR032305 GTP-binding protein, middle domain MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 PIRSF PIRSF006809 1 414 5.0E-151 T 01-11-2018 IPR016496 GTPase HflX GO:0005525 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 Hamap MF_00900 GTPase HflX [hflX]. 26 384 46.161 T 01-11-2018 IPR016496 GTPase HflX GO:0005525 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 Pfam PF13167 GTP-binding GTPase N-terminal 24 111 8.1E-33 T 01-11-2018 IPR025121 GTPase HflX, N-terminal MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 Gene3D G3DSA:3.40.50.11060 18 137 1.0E-40 T 01-11-2018 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 SUPERFAMILY SSF52540 196 366 4.82E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 Gene3D G3DSA:3.40.50.300 198 363 2.1E-34 T 01-11-2018 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 6 354 2.0E-145 T 01-11-2018 IPR016496 GTPase HflX GO:0005525 MLA2C4_19365 4c9abf5a70744ae88d671645c69e08bb 424 Pfam PF01926 50S ribosome-binding GTPase 198 317 4.5E-19 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 SMART SM00382 363 555 8.7E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 Pfam PF00664 ABC transporter transmembrane region 21 292 4.9E-41 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 Pfam PF00005 ABC transporter 354 501 1.5E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 SUPERFAMILY SSF90123 8 325 1.14E-73 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 Gene3D G3DSA:3.40.50.300 328 584 3.3E-82 T 01-11-2018 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 Gene3D G3DSA:1.20.1560.10 3 320 9.8E-78 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_04645 419fd7069f67c74360f4f4a414c141fd 586 SUPERFAMILY SSF52540 328 573 2.17E-81 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_16895 a49b79bcd1bb5b2826cf19dda43eca6f 219 Gene3D G3DSA:1.10.510.10 31 181 6.2E-8 T 01-11-2018 MLA2C4_16895 a49b79bcd1bb5b2826cf19dda43eca6f 219 SUPERFAMILY SSF56112 37 187 3.84E-12 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_18865 329dbf48e222cb7209628136df089353 486 Gene3D G3DSA:3.30.300.310 384 483 2.6E-26 T 01-11-2018 MLA2C4_18865 329dbf48e222cb7209628136df089353 486 SUPERFAMILY SSF56801 10 480 7.46E-106 T 01-11-2018 MLA2C4_18865 329dbf48e222cb7209628136df089353 486 Pfam PF00501 AMP-binding enzyme 14 386 4.5E-61 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_18865 329dbf48e222cb7209628136df089353 486 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_18865 329dbf48e222cb7209628136df089353 486 Gene3D G3DSA:3.40.50.12780 3 379 7.5E-73 T 01-11-2018 MLA2C4_18865 329dbf48e222cb7209628136df089353 486 Pfam PF13193 AMP-binding enzyme C-terminal domain 397 468 1.7E-17 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_06570 e8e4bd4e91e33695152c790eae350fdb 196 Gene3D G3DSA:3.40.50.150 21 196 2.3E-29 T 01-11-2018 MLA2C4_06570 e8e4bd4e91e33695152c790eae350fdb 196 Pfam PF13649 Methyltransferase domain 49 145 1.5E-16 T 01-11-2018 MLA2C4_06570 e8e4bd4e91e33695152c790eae350fdb 196 SUPERFAMILY SSF53335 27 185 1.75E-29 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_19245 ed363653a7b86f2182335f1c0bf901e7 323 SUPERFAMILY SSF53795 117 183 2.84E-15 T 01-11-2018 MLA2C4_19245 ed363653a7b86f2182335f1c0bf901e7 323 Gene3D G3DSA:3.40.50.300 116 202 3.2E-11 T 01-11-2018 MLA2C4_06135 f715b5bf7b5ded0e0c6dcfe1bc9d61af 65 Pfam PF12758 Protein of unknown function (DUF3813) 1 61 1.3E-27 T 01-11-2018 IPR024217 Protein of unknown function DUF3813 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 SUPERFAMILY SSF50447 360 442 5.82E-25 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 2.9E-14 T 01-11-2018 IPR006847 Translation initiation factor IF-2, N-terminal MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 113 161 5.9E-16 T 01-11-2018 IPR006847 Translation initiation factor IF-2, N-terminal MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Gene3D G3DSA:2.40.30.10 360 477 2.5E-40 T 01-11-2018 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 190 347 4.0E-38 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Gene3D G3DSA:2.40.30.10 590 686 8.2E-36 T 01-11-2018 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Gene3D G3DSA:3.40.50.10050 482 589 6.0E-39 T 01-11-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 SUPERFAMILY SSF52540 176 360 1.67E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 686 17.514 T 01-11-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Pfam PF11987 Translation-initiation factor 2 473 578 1.5E-37 T 01-11-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 SUPERFAMILY SSF50447 589 686 2.08E-33 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Pfam PF00009 Elongation factor Tu GTP binding domain 193 348 3.3E-37 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 SUPERFAMILY SSF52156 467 595 1.96E-39 T 01-11-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 104 686 2.3E-279 T 01-11-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 ProSitePatterns PS01176 Initiation factor 2 signature. 639 661 - T 01-11-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Gene3D G3DSA:3.40.50.300 185 359 1.2E-75 T 01-11-2018 MLA2C4_19935 5bfbbdef01a25170c09d29cdea80ee93 686 Gene3D G3DSA:1.10.10.2480 1 88 4.9E-13 T 01-11-2018 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 01-11-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 01-11-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.0E-100 T 01-11-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 Gene3D G3DSA:3.20.20.140 1 255 5.1E-113 T 01-11-2018 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 Pfam PF01026 TatD related DNase 3 252 1.7E-88 T 01-11-2018 IPR001130 TatD family GO:0016788 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 PIRSF PIRSF005902 1 255 2.3E-91 T 01-11-2018 IPR001130 TatD family GO:0016788 MLA2C4_00230 6cf4d9d0c2d393d5c75826e28b465d14 255 SUPERFAMILY SSF51556 1 254 2.21E-98 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_05685 8d6a906f50ecabec336d4c77bb0cd68e 158 Pfam PF03703 Bacterial PH domain 72 147 7.4E-17 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 Gene3D G3DSA:1.10.1520.10 15 168 2.0E-49 T 01-11-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 Hamap MF_00104 Ribonuclease 3 [rnc]. 22 238 31.871 T 01-11-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 Pfam PF00035 Double-stranded RNA binding motif 175 241 1.6E-17 T 01-11-2018 IPR014720 Double-stranded RNA-binding domain MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 SUPERFAMILY SSF69065 15 177 1.31E-53 T 01-11-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 Pfam PF14622 Ribonuclease-III-like 32 160 1.6E-37 T 01-11-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 22 241 2.8E-81 T 01-11-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 SMART SM00535 34 169 4.2E-59 T 01-11-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 Gene3D G3DSA:3.30.160.20 173 244 4.2E-23 T 01-11-2018 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 ProSitePatterns PS00517 Ribonuclease III family signature. 58 66 - T 01-11-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 SMART SM00358 175 242 4.1E-22 T 01-11-2018 IPR014720 Double-stranded RNA-binding domain MLA2C4_20115 e58f4b96684b31b344737bfb42fd1676 245 SUPERFAMILY SSF54768 131 241 2.99E-24 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 SUPERFAMILY SSF81653 115 228 5.62E-30 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Pfam PF00689 Cation transporting ATPase, C-terminus 699 885 2.7E-51 T 01-11-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 219 356 2.7E-29 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 84 184 6.0E-21 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 584 701 1.5E-36 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 523 4.1E-43 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 544 4.1E-43 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 638 650 4.1E-43 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 633 4.1E-43 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 4.1E-43 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 4.1E-43 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Gene3D G3DSA:2.70.150.10 16 232 0.0 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Pfam PF00122 E1-E2 ATPase 112 309 1.3E-55 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Gene3D G3DSA:3.40.1110.10 339 519 0.0 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 628 1.4E-23 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 249 271 1.0E-8 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 322 343 1.0E-8 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Gene3D G3DSA:3.40.50.1000 326 659 0.0 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 SUPERFAMILY SSF81660 336 516 8.83E-52 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Gene3D G3DSA:1.20.1110.10 55 884 0.0 T 01-11-2018 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 SMART SM00831 3 77 3.2E-27 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 SUPERFAMILY SSF56784 327 718 1.32E-63 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 SUPERFAMILY SSF81665 2 887 9.55E-137 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_02435 53faf6822f78b108d867a7333e917bf2 888 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 72 6.8E-19 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 3.0E-11 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 3.0E-11 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 3.0E-11 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 Gene3D G3DSA:3.40.50.12740 2 200 2.7E-58 T 01-11-2018 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 4.3E-17 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 SMART SM00448 2 115 7.7E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 SMART SM00421 137 194 2.5E-21 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 SUPERFAMILY SSF46894 129 200 4.42E-19 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 Pfam PF00072 Response regulator receiver domain 4 115 1.5E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_27710 f2553db6fed348c2c3611f94f369c174 200 SUPERFAMILY SSF52172 1 128 1.57E-30 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 321 419 3.9E-20 T 01-11-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 SUPERFAMILY SSF51735 163 313 3.45E-32 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 Gene3D G3DSA:3.30.460.30 1 158 7.4E-52 T 01-11-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 Gene3D G3DSA:3.40.50.720 161 313 2.1E-43 T 01-11-2018 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 420 28.921 T 01-11-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 3.7E-146 T 01-11-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 SUPERFAMILY SSF69742 2 158 1.02E-44 T 01-11-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 01-11-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.3E-44 T 01-11-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 SUPERFAMILY SSF69075 317 420 1.44E-16 T 01-11-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 PIRSF PIRSF000445 1 434 1.1E-149 T 01-11-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MLA2C4_23280 8181d0386386e26455da7952432f7bc1 444 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 2.5E-44 T 01-11-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Pfam PF03717 Penicillin-binding Protein dimerisation domain 150 317 3.6E-36 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Gene3D G3DSA:3.40.710.10 331 661 3.5E-85 T 01-11-2018 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Gene3D G3DSA:3.30.1390.30 171 242 2.2E-51 T 01-11-2018 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Gene3D G3DSA:3.10.450.100 23 138 1.1E-28 T 01-11-2018 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 SUPERFAMILY SSF54427 27 141 2.02E-34 T 01-11-2018 IPR032710 NTF2-like domain superfamily MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Gene3D G3DSA:3.90.1310.10 150 327 2.2E-51 T 01-11-2018 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 SUPERFAMILY SSF56519 144 331 1.44E-43 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 SUPERFAMILY SSF56601 332 660 7.32E-82 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 24 142 4.2E-40 T 01-11-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 MLA2C4_11205 5ea843eb1df33bb82bbe1825ba75b1cf 661 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 658 1.4E-67 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_26330 4a82d63cf44a3d408f47b28df0e161f1 393 Pfam PF07670 Nucleoside recognition 91 189 1.4E-5 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_26330 4a82d63cf44a3d408f47b28df0e161f1 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 7.8E-57 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_26330 4a82d63cf44a3d408f47b28df0e161f1 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.9E-20 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_14280 554e7198908d6b36127210f90d548e4e 147 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_14280 554e7198908d6b36127210f90d548e4e 147 Gene3D G3DSA:3.90.79.10 1 139 1.2E-28 T 01-11-2018 MLA2C4_14280 554e7198908d6b36127210f90d548e4e 147 Pfam PF00293 NUDIX domain 7 117 1.2E-17 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_14280 554e7198908d6b36127210f90d548e4e 147 SUPERFAMILY SSF55811 5 125 1.9E-26 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_14280 554e7198908d6b36127210f90d548e4e 147 PRINTS PR00502 NUDIX hydrolase family signature 46 61 9.8E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_14280 554e7198908d6b36127210f90d548e4e 147 PRINTS PR00502 NUDIX hydrolase family signature 32 46 9.8E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 Pfam PF00072 Response regulator receiver domain 3 122 6.4E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 SUPERFAMILY SSF81606 179 376 6.8E-8 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 Gene3D G3DSA:3.40.50.2300 1 132 2.2E-37 T 01-11-2018 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 SMART SM00448 1 122 4.6E-35 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 SMART SM00331 163 377 2.9E-25 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 Gene3D G3DSA:3.60.40.10 134 378 2.5E-51 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 SUPERFAMILY SSF52172 2 142 7.12E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_05330 c7c4a53e04b6e19c7bef32219a3e103a 380 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 190 377 1.6E-38 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_09510 ea227db8d39657b919d21c4859eae5c6 214 Gene3D G3DSA:2.40.50.40 106 176 1.6E-31 T 01-11-2018 MLA2C4_09510 ea227db8d39657b919d21c4859eae5c6 214 SMART SM00850 116 213 9.4E-30 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_09510 ea227db8d39657b919d21c4859eae5c6 214 Gene3D G3DSA:2.20.25.10 177 214 2.3E-24 T 01-11-2018 MLA2C4_09510 ea227db8d39657b919d21c4859eae5c6 214 Pfam PF04397 LytTr DNA-binding domain 118 212 3.2E-27 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_09510 ea227db8d39657b919d21c4859eae5c6 214 PIRSF PIRSF036613 1 214 6.4E-139 T 01-11-2018 IPR012072 LytTR signal transduction protein, putative MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 SUPERFAMILY SSF53955 73 283 8.15E-74 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 638 2.6E-177 T 01-11-2018 MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 Gene3D G3DSA:3.40.710.10 325 649 3.7E-207 T 01-11-2018 MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 SUPERFAMILY SSF56601 245 653 6.61E-106 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 Pfam PF00912 Transglycosylase 84 260 1.7E-65 T 01-11-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 Gene3D G3DSA:1.10.3810.10 94 286 3.7E-207 T 01-11-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 Gene3D G3DSA:3.90.1310.20 79 535 3.7E-207 T 01-11-2018 MLA2C4_12090 3b99d1739c2a54578c334a38b29aa4ed 829 Pfam PF00905 Penicillin binding protein transpeptidase domain 350 635 2.7E-45 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_26440 020f38bf3ef232ab202ecb369f9b93d3 171 Gene3D G3DSA:3.40.630.30 4 171 5.3E-52 T 01-11-2018 MLA2C4_26440 020f38bf3ef232ab202ecb369f9b93d3 171 Pfam PF13302 Acetyltransferase (GNAT) domain 5 138 2.8E-23 T 01-11-2018 IPR000182 GNAT domain MLA2C4_26440 020f38bf3ef232ab202ecb369f9b93d3 171 SUPERFAMILY SSF55729 3 162 2.09E-42 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_20795 5a038ea9977f6e5577a99ef6785d6e71 221 SUPERFAMILY SSF116726 135 220 2.62E-21 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_20795 5a038ea9977f6e5577a99ef6785d6e71 221 Gene3D G3DSA:3.30.70.1450 141 218 3.3E-28 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_20795 5a038ea9977f6e5577a99ef6785d6e71 221 Pfam PF02080 TrkA-C domain 153 219 2.3E-17 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MLA2C4_20795 5a038ea9977f6e5577a99ef6785d6e71 221 Gene3D G3DSA:3.40.50.720 2 140 1.1E-38 T 01-11-2018 MLA2C4_20795 5a038ea9977f6e5577a99ef6785d6e71 221 Pfam PF02254 TrkA-N domain 8 123 1.2E-29 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MLA2C4_20795 5a038ea9977f6e5577a99ef6785d6e71 221 SUPERFAMILY SSF51735 7 137 1.64E-37 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_16355 1eb319c77ea41fec10bff666b65fe76c 125 SUPERFAMILY SSF47413 3 65 1.98E-15 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_16355 1eb319c77ea41fec10bff666b65fe76c 125 SMART SM00530 4 59 1.9E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_16355 1eb319c77ea41fec10bff666b65fe76c 125 Gene3D G3DSA:1.10.260.40 3 114 3.3E-20 T 01-11-2018 MLA2C4_16355 1eb319c77ea41fec10bff666b65fe76c 125 Pfam PF01381 Helix-turn-helix 6 59 8.9E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_21900 4579df530f5866ce3bf3d30ad71ea3ef 218 Gene3D G3DSA:3.30.300.270 102 217 2.1E-33 T 01-11-2018 IPR038503 Stage III sporulation protein AH-like superfamily MLA2C4_21900 4579df530f5866ce3bf3d30ad71ea3ef 218 Pfam PF12685 SpoIIIAH-like protein 5 205 2.3E-35 T 01-11-2018 IPR024232 Stage III sporulation protein AH-like MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 Gene3D G3DSA:3.30.450.40 56 178 1.0E-44 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 SMART SM00966 8 52 1.1E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 1.0E-44 T 01-11-2018 IPR039472 Sporulation stage V protein T, GAF domain MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 1.6E-92 T 01-11-2018 IPR014213 Sporulation stage V, protein T MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 01-11-2018 MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 PIRSF PIRSF026579 1 178 7.4E-95 T 01-11-2018 IPR014213 Sporulation stage V, protein T MLA2C4_00305 72eaf6832d65bb1b9c688e3aaa798ae6 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 Gene3D G3DSA:3.40.50.720 1 148 6.1E-50 T 01-11-2018 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 SUPERFAMILY SSF51735 3 148 8.67E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 381 1.2E-160 T 01-11-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 380 46.95 T 01-11-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 130 1.2E-42 T 01-11-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 SUPERFAMILY SSF55347 124 262 5.23E-58 T 01-11-2018 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 Gene3D G3DSA:1.10.1740.10 300 385 1.2E-30 T 01-11-2018 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 375 5.4E-42 T 01-11-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 7.2E-39 T 01-11-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 SUPERFAMILY SSF69055 289 382 8.89E-34 T 01-11-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_17570 0f76ac73b714bda6c4fa9e8b168779c6 385 PIRSF PIRSF006205 2 385 3.8E-163 T 01-11-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MLA2C4_22545 a8b4cc323364c62a7d922f6e23ffb609 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 367 3.7E-130 T 01-11-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 MLA2C4_22545 a8b4cc323364c62a7d922f6e23ffb609 379 SMART SM00729 2 223 1.6E-64 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_22545 a8b4cc323364c62a7d922f6e23ffb609 379 Pfam PF06969 HemN C-terminal domain 303 365 1.2E-16 T 01-11-2018 IPR010723 HemN, C-terminal MLA2C4_22545 a8b4cc323364c62a7d922f6e23ffb609 379 Pfam PF04055 Radical SAM superfamily 7 177 1.6E-25 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_22545 a8b4cc323364c62a7d922f6e23ffb609 379 SUPERFAMILY SSF102114 5 377 7.46E-120 T 01-11-2018 MLA2C4_22545 a8b4cc323364c62a7d922f6e23ffb609 379 Gene3D G3DSA:3.80.30.20 3 301 5.6E-104 T 01-11-2018 IPR023404 Radical SAM, alpha/beta horseshoe MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 257 7.9E-17 T 01-11-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 PIRSF PIRSF006816 1 259 2.1E-69 T 01-11-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 Gene3D G3DSA:3.40.50.80 103 215 4.4E-24 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 Gene3D G3DSA:2.10.240.10 216 259 1.3E-17 T 01-11-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 SUPERFAMILY SSF52343 95 258 1.57E-30 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 5.3E-8 T 01-11-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 112 131 5.3E-8 T 01-11-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 189 197 5.3E-8 T 01-11-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 Pfam PF00970 Oxidoreductase FAD-binding domain 8 98 1.3E-4 T 01-11-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 259 38.4 T 01-11-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 SUPERFAMILY SSF63380 1 100 4.84E-22 T 01-11-2018 IPR017938 Riboflavin synthase-like beta-barrel MLA2C4_20310 e620fe4ce132ff9c2b7136140cfb2965 259 Gene3D G3DSA:2.40.30.10 1 98 2.8E-30 T 01-11-2018 MLA2C4_23290 69306c1f1f509c79f1ae9392cbabd3de 138 SUPERFAMILY SSF82784 1 137 5.5E-43 T 01-11-2018 IPR036102 OsmC/Ohr superfamily MLA2C4_23290 69306c1f1f509c79f1ae9392cbabd3de 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 2.0E-56 T 01-11-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MLA2C4_23290 69306c1f1f509c79f1ae9392cbabd3de 138 Gene3D G3DSA:3.30.300.20 45 138 1.5E-35 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_23290 69306c1f1f509c79f1ae9392cbabd3de 138 Gene3D G3DSA:2.20.25.10 1 44 1.3E-18 T 01-11-2018 MLA2C4_23290 69306c1f1f509c79f1ae9392cbabd3de 138 Pfam PF02566 OsmC-like protein 40 135 1.1E-18 T 01-11-2018 IPR003718 OsmC/Ohr family MLA2C4_18070 165a1ef3e0b7423484dba0dd96f6de48 254 Pfam PF05675 Protein of unknown function (DUF817) 6 240 5.7E-104 T 01-11-2018 IPR008535 Protein of unknown function DUF817 MLA2C4_18070 165a1ef3e0b7423484dba0dd96f6de48 254 PIRSF PIRSF009141 1 254 2.9E-125 T 01-11-2018 IPR008535 Protein of unknown function DUF817 MLA2C4_14625 10c50113406576112ec3ef5ea7386235 145 SUPERFAMILY SSF55811 9 142 4.06E-30 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_14625 10c50113406576112ec3ef5ea7386235 145 PRINTS PR00502 NUDIX hydrolase family signature 45 59 1.8E-9 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_14625 10c50113406576112ec3ef5ea7386235 145 PRINTS PR00502 NUDIX hydrolase family signature 59 74 1.8E-9 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_14625 10c50113406576112ec3ef5ea7386235 145 Pfam PF00293 NUDIX domain 21 132 6.7E-18 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_14625 10c50113406576112ec3ef5ea7386235 145 Gene3D G3DSA:3.90.79.10 1 145 1.4E-46 T 01-11-2018 MLA2C4_14625 10c50113406576112ec3ef5ea7386235 145 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 Pfam PF00155 Aminotransferase class I and II 139 467 4.8E-33 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 SMART SM00345 17 76 1.2E-13 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 Gene3D G3DSA:1.10.10.10 1 86 2.6E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 Gene3D G3DSA:3.40.640.10 147 367 1.4E-98 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 SUPERFAMILY SSF46785 7 80 1.69E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 Gene3D G3DSA:3.90.1150.10 109 469 1.4E-98 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 SUPERFAMILY SSF53383 102 475 3.94E-88 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_14530 9d9dd433c9565ef70cda56428ac057dc 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.1E-14 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 2.1E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 409 2.1E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 2.1E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 2.1E-18 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 257 1.5E-10 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 SUPERFAMILY SSF55874 254 414 4.58E-37 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 Pfam PF13426 PAS domain 96 183 7.7E-8 T 01-11-2018 IPR000014 PAS domain MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 SMART SM00091 82 149 0.0017 T 01-11-2018 IPR000014 PAS domain MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 Gene3D G3DSA:1.10.287.130 200 257 1.2E-12 T 01-11-2018 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 Gene3D G3DSA:3.30.450.20 76 183 3.0E-12 T 01-11-2018 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 SMART SM00387 306 412 1.9E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 81 179 4.2E-6 T 01-11-2018 IPR000014 PAS domain MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 SUPERFAMILY SSF47384 187 258 1.0E-10 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 SUPERFAMILY SSF55785 78 182 2.27E-11 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 409 1.2E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 SMART SM00388 196 261 3.7E-8 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07690 9e3f54f069bbca22b6e028e553187cb9 422 Gene3D G3DSA:3.30.565.10 263 411 6.0E-39 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 1.6E-25 T 01-11-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 SUPERFAMILY SSF46785 5 78 6.28E-25 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 Gene3D G3DSA:3.30.1360.40 68 149 6.8E-31 T 01-11-2018 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 1.0E-28 T 01-11-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 1.0E-28 T 01-11-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 1.0E-28 T 01-11-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 1.0E-28 T 01-11-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 8.3E-53 T 01-11-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 SUPERFAMILY SSF55252 80 149 1.96E-22 T 01-11-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 Gene3D G3DSA:1.10.10.10 4 67 9.0E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 71.897 T 01-11-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 7.2E-31 T 01-11-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 MLA2C4_21840 559d6e6e30e6b761c0924a760fd97357 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 4.0E-31 T 01-11-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 SUPERFAMILY SSF81442 13 521 1.96E-181 T 01-11-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 191 210 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 425 446 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 7.3E-106 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 Gene3D G3DSA:1.20.210.10 2 527 3.8E-207 T 01-11-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 01-11-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 468 7.7E-148 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 Gene3D G3DSA:1.10.287.70 540 606 5.8E-5 T 01-11-2018 MLA2C4_20595 cef675f83c47253eac89570a221af01b 620 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 519 8.8E-207 T 01-11-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 PIRSF PIRSF000774 1 434 2.2E-134 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 413 420 - T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 Pfam PF04552 Sigma-54, DNA binding domain 274 432 1.8E-62 T 01-11-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 Pfam PF04963 Sigma-54 factor, core binding domain 78 261 2.5E-54 T 01-11-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 Gene3D G3DSA:1.10.10.1330 81 207 7.1E-25 T 01-11-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 321 340 - T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 Gene3D G3DSA:1.10.10.60 373 433 2.1E-23 T 01-11-2018 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 PRINTS PR00045 Sigma-54 factor signature 408 426 2.0E-26 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 PRINTS PR00045 Sigma-54 factor signature 147 164 2.0E-26 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 PRINTS PR00045 Sigma-54 factor signature 333 345 2.0E-26 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 PRINTS PR00045 Sigma-54 factor signature 349 360 2.0E-26 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 432 7.7E-139 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_26600 21449a38654e7369eb87b1c7807a236a 435 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 2.2E-13 T 01-11-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MLA2C4_03965 9304a5f9082829b8951f9e19c604604a 273 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 9 264 9.0E-110 T 01-11-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_03965 9304a5f9082829b8951f9e19c604604a 273 SUPERFAMILY SSF53613 4 267 1.45E-86 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_03965 9304a5f9082829b8951f9e19c604604a 273 Gene3D G3DSA:3.40.1190.20 1 272 7.1E-109 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_03965 9304a5f9082829b8951f9e19c604604a 273 Pfam PF08543 Phosphomethylpyrimidine kinase 16 262 5.2E-103 T 01-11-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 200 211 - T 01-11-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Gene3D G3DSA:2.60.40.4070 752 807 1.4E-6 T 01-11-2018 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 SUPERFAMILY SSF52025 381 473 1.44E-14 T 01-11-2018 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 237 247 - T 01-11-2018 IPR022398 Peptidase S8, subtilisin, His-active site MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Pfam PF02225 PA domain 384 467 9.0E-12 T 01-11-2018 IPR003137 PA domain MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Gene3D G3DSA:3.30.70.80 56 152 1.2E-5 T 01-11-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Pfam PF00082 Subtilase family 195 583 3.2E-65 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Pfam PF13860 FlgD Ig-like domain 765 800 5.0E-7 T 01-11-2018 IPR025965 FlgD Ig-like domain MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 5.4E-21 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 214 5.4E-21 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 PRINTS PR00723 Subtilisin serine protease family (S8) signature 528 544 5.4E-21 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Pfam PF05922 Peptidase inhibitor I9 64 158 4.9E-10 T 01-11-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 SUPERFAMILY SSF52743 172 592 2.62E-88 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 Gene3D G3DSA:3.50.30.30 358 486 1.1E-20 T 01-11-2018 MLA2C4_22730 f1546846e304a50a6d51bc1693b782a0 915 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 529 539 - T 01-11-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 Gene3D G3DSA:3.40.50.300 14 209 6.4E-30 T 01-11-2018 MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 PRINTS PR00988 Uridine kinase signature 187 200 6.0E-8 T 01-11-2018 MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 PRINTS PR00988 Uridine kinase signature 166 177 6.0E-8 T 01-11-2018 MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 PRINTS PR00988 Uridine kinase signature 18 35 6.0E-8 T 01-11-2018 MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 PRINTS PR00988 Uridine kinase signature 152 162 6.0E-8 T 01-11-2018 MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 SUPERFAMILY SSF52540 20 204 6.79E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_16755 967cbd930e0a23c49f1252a9e214eacc 218 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 20 201 6.4E-21 T 01-11-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 235 6.3E-20 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 293 306 6.3E-20 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 614 630 6.3E-20 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Pfam PF00082 Subtilase family 216 665 1.3E-66 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 615 625 - T 01-11-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Gene3D G3DSA:3.50.30.30 445 548 2.3E-33 T 01-11-2018 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 PIRSF PIRSF037844 1 1407 0.0 T 01-11-2018 IPR017292 Peptidase S8A, Vpr MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Gene3D G3DSA:2.60.40.4130 1231 1384 1.0E-13 T 01-11-2018 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 221 232 - T 01-11-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 SUPERFAMILY SSF52025 460 549 7.85E-17 T 01-11-2018 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Pfam PF06280 Fn3-like domain 737 809 7.4E-7 T 01-11-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Pfam PF02225 PA domain 462 537 8.9E-17 T 01-11-2018 IPR003137 PA domain MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Pfam PF05922 Peptidase inhibitor I9 87 183 2.3E-8 T 01-11-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Gene3D G3DSA:3.40.50.200 189 444 7.4E-54 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 Gene3D G3DSA:3.40.50.200 549 677 8.8E-34 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 297 307 - T 01-11-2018 IPR022398 Peptidase S8, subtilisin, His-active site MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 SUPERFAMILY SSF63446 1320 1375 2.22E-7 T 01-11-2018 IPR036439 Dockerin domain superfamily GO:0000272 MLA2C4_25335 3f14863cc45edc0b1ca796fcc3a3bfa8 1407 SUPERFAMILY SSF52743 200 674 3.8E-84 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_25075 15ff2d382f58207f4fc9a783356f0931 175 Pfam PF00156 Phosphoribosyl transferase domain 14 158 1.1E-24 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_25075 15ff2d382f58207f4fc9a783356f0931 175 SUPERFAMILY SSF53271 4 174 3.77E-52 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_25075 15ff2d382f58207f4fc9a783356f0931 175 Gene3D G3DSA:3.40.50.2020 1 175 9.9E-66 T 01-11-2018 MLA2C4_25075 15ff2d382f58207f4fc9a783356f0931 175 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 172 3.2E-64 T 01-11-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 MLA2C4_00270 eff2ebb4f386e13cf4151eb099424d5b 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 8.5E-56 T 01-11-2018 IPR006056 RidA family Reactome: R-HSA-8849175 MLA2C4_00270 eff2ebb4f386e13cf4151eb099424d5b 124 SUPERFAMILY SSF55298 2 123 3.61E-48 T 01-11-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MLA2C4_00270 eff2ebb4f386e13cf4151eb099424d5b 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 2.6E-47 T 01-11-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MLA2C4_00270 eff2ebb4f386e13cf4151eb099424d5b 124 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 01-11-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 MLA2C4_00270 eff2ebb4f386e13cf4151eb099424d5b 124 Gene3D G3DSA:3.30.1330.40 1 124 7.9E-55 T 01-11-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MLA2C4_23640 e5ab0c0aef4358defcac3d7b420684f3 441 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 418 9.5E-137 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_23640 e5ab0c0aef4358defcac3d7b420684f3 441 Pfam PF05525 Branched-chain amino acid transport protein 9 430 1.1E-143 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 PIRSF PIRSF002599 1 66 2.1E-24 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 SUPERFAMILY SSF50249 1 64 9.43E-26 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 Gene3D G3DSA:2.40.50.140 1 66 2.0E-31 T 01-11-2018 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.1E-30 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 01-11-2018 IPR019844 Cold-shock conserved site MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 PRINTS PR00050 Cold shock protein signature 39 57 4.3E-19 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 PRINTS PR00050 Cold shock protein signature 4 19 4.3E-19 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 PRINTS PR00050 Cold shock protein signature 24 33 4.3E-19 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_25290 69e6d21c7f3b10d0717291fc08814c51 66 SMART SM00357 3 66 2.4E-30 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_07230 e580c3b6216c1ce4fca5988c09d0bf61 184 Gene3D G3DSA:3.40.50.850 2 184 4.8E-54 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_07230 e580c3b6216c1ce4fca5988c09d0bf61 184 SUPERFAMILY SSF52499 3 182 4.84E-48 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_07230 e580c3b6216c1ce4fca5988c09d0bf61 184 Pfam PF00857 Isochorismatase family 6 178 1.1E-36 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_24585 70b4f63d774239c0848aa575dc52d6e3 924 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 16 35 2.3E-7 T 01-11-2018 IPR021201 Leader peptide, exosporium MLA2C4_24585 70b4f63d774239c0848aa575dc52d6e3 924 Pfam PF01391 Collagen triple helix repeat (20 copies) 84 141 2.9E-8 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_24585 70b4f63d774239c0848aa575dc52d6e3 924 Pfam PF01391 Collagen triple helix repeat (20 copies) 36 93 9.6E-9 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_08005 9192694ec1755a6cf8d247a5e815efba 170 SUPERFAMILY SSF50022 6 160 1.57E-30 T 01-11-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MLA2C4_08005 9192694ec1755a6cf8d247a5e815efba 170 Pfam PF00355 Rieske [2Fe-2S] domain 51 149 4.2E-14 T 01-11-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MLA2C4_08005 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 121 133 1.5E-5 T 01-11-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MLA2C4_08005 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 108 1.5E-5 T 01-11-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MLA2C4_08005 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 145 1.5E-5 T 01-11-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MLA2C4_08005 9192694ec1755a6cf8d247a5e815efba 170 Gene3D G3DSA:2.102.10.10 40 166 5.2E-27 T 01-11-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 01-11-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 Pfam PF00344 SecY translocase 68 415 2.5E-114 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 271 290 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 311 333 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 400 418 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 366 384 7.5E-102 T 01-11-2018 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 Gene3D G3DSA:1.10.3370.10 1 427 2.0E-161 T 01-11-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 431 29.711 T 01-11-2018 IPR026593 Protein translocase subunit SecY MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 SUPERFAMILY SSF103491 1 422 7.45E-130 T 01-11-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 PIRSF PIRSF004557 1 433 1.3E-130 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 01-11-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00775 86a02acaa74ed695199578ad9ebcd9b2 433 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 427 2.3E-147 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_18340 4ca04472b29731e2d6d6ff3df551c748 265 Pfam PF00005 ABC transporter 29 180 2.4E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18340 4ca04472b29731e2d6d6ff3df551c748 265 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_18340 4ca04472b29731e2d6d6ff3df551c748 265 PIRSF PIRSF039085 10 256 1.2E-109 T 01-11-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MLA2C4_18340 4ca04472b29731e2d6d6ff3df551c748 265 Gene3D G3DSA:3.40.50.300 11 263 2.0E-78 T 01-11-2018 MLA2C4_18340 4ca04472b29731e2d6d6ff3df551c748 265 SUPERFAMILY SSF52540 13 250 1.08E-78 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18340 4ca04472b29731e2d6d6ff3df551c748 265 SMART SM00382 38 234 4.5E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 260 6.3E-98 T 01-11-2018 IPR006222 Aminomethyltransferase, folate-binding domain MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 364 3.0E-145 T 01-11-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 358 3.4E-29 T 01-11-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Gene3D G3DSA:2.40.30.110 282 364 3.9E-32 T 01-11-2018 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Gene3D G3DSA:3.30.1360.120 6 237 6.2E-94 T 01-11-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Gene3D G3DSA:3.30.70.1400 53 138 6.2E-94 T 01-11-2018 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Gene3D G3DSA:4.10.1250.10 238 281 1.6E-18 T 01-11-2018 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 SUPERFAMILY SSF103025 4 283 9.89E-102 T 01-11-2018 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 364 48.7 T 01-11-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 PIRSF PIRSF006487 1 366 2.0E-109 T 01-11-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MLA2C4_22115 3350d5e0fbbef390eff57ea2d40a61c6 366 SUPERFAMILY SSF101790 275 364 3.92E-27 T 01-11-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 SUPERFAMILY SSF118215 6 402 9.94E-129 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 6.0E-126 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 01-11-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.2E-36 T 01-11-2018 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 Gene3D G3DSA:1.10.3860.10 1 419 5.5E-140 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_07565 6d6818bd7127ee9d0f32a16455cf1513 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 01-11-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MLA2C4_20205 bc19117572983909bec999a0902bf803 314 Pfam PF00551 Formyl transferase 3 180 2.8E-39 T 01-11-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 01-11-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 309 1.3E-113 T 01-11-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 SUPERFAMILY SSF53328 2 206 2.09E-67 T 01-11-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 7.5E-29 T 01-11-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 Gene3D G3DSA:3.40.50.170 1 206 1.1E-88 T 01-11-2018 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 35.635 T 01-11-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 SUPERFAMILY SSF50486 205 310 2.98E-32 T 01-11-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MLA2C4_20205 bc19117572983909bec999a0902bf803 314 Gene3D G3DSA:3.10.25.10 207 314 1.2E-42 T 01-11-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_22045 db1beabd68667c02443858742e7ca966 110 SUPERFAMILY SSF103481 5 99 1.03E-15 T 01-11-2018 MLA2C4_22045 db1beabd68667c02443858742e7ca966 110 Gene3D G3DSA:1.10.3730.20 1 105 6.3E-22 T 01-11-2018 MLA2C4_22045 db1beabd68667c02443858742e7ca966 110 Pfam PF00893 Small Multidrug Resistance protein 1 90 1.2E-20 T 01-11-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MLA2C4_09845 292b71f58aac50dde26b966a1df1d21f 135 Gene3D G3DSA:3.30.429.10 2 134 1.2E-37 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily MLA2C4_09845 292b71f58aac50dde26b966a1df1d21f 135 Pfam PF14552 Tautomerase enzyme 39 123 6.7E-21 T 01-11-2018 IPR037479 Tautomerase, MSAD family MLA2C4_09845 292b71f58aac50dde26b966a1df1d21f 135 SUPERFAMILY SSF55331 2 132 2.33E-34 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 13 602 7.2E-224 T 01-11-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 Pfam PF08439 Oligopeptidase F 120 189 2.4E-26 T 01-11-2018 IPR013647 Oligopeptidase F, N-terminal domain MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 Pfam PF01432 Peptidase family M3 211 591 8.4E-83 T 01-11-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 Gene3D G3DSA:1.10.1370.20 234 607 3.5E-144 T 01-11-2018 MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 SUPERFAMILY SSF55486 9 587 4.56E-142 T 01-11-2018 MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 Gene3D G3DSA:1.20.140.70 30 185 2.1E-59 T 01-11-2018 MLA2C4_06280 b6ceedefa8c62c4f2bd0623d11275533 608 Gene3D G3DSA:1.10.287.830 187 233 5.2E-22 T 01-11-2018 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 PIRSF PIRSF001394 11 524 5.5E-201 T 01-11-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 SUPERFAMILY SSF117457 335 505 9.02E-53 T 01-11-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 Pfam PF05681 Fumarate hydratase (Fumerase) 25 300 6.9E-71 T 01-11-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 Gene3D G3DSA:3.20.130.10 319 506 1.7E-65 T 01-11-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 24 299 1.9E-60 T 01-11-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 Pfam PF05683 Fumarase C-terminus 308 507 5.9E-64 T 01-11-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MLA2C4_02530 157844580a6360bdefe23c95ecf3c64c 525 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 344 505 1.3E-51 T 01-11-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 SUPERFAMILY SSF53383 10 414 7.62E-75 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 Hamap MF_01970 Kynureninase [kynU]. 3 412 39.94 T 01-11-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 Gene3D G3DSA:3.40.640.10 47 316 4.4E-142 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 Pfam PF00266 Aminotransferase class-V 84 373 1.3E-19 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 TIGRFAM TIGR01814 kynureninase: kynureninase 14 413 1.8E-121 T 01-11-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 Gene3D G3DSA:3.90.1150.10 17 412 4.4E-142 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_14615 af4718db47afe5fbf24f3cb6910e70bc 428 PIRSF PIRSF038800 6 420 7.3E-153 T 01-11-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MLA2C4_22735 4125a165e9746f27496011fa78e6261d 584 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 22 146 6.7E-11 T 01-11-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MLA2C4_22735 4125a165e9746f27496011fa78e6261d 584 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 201 290 5.9E-19 T 01-11-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MLA2C4_22735 4125a165e9746f27496011fa78e6261d 584 SUPERFAMILY SSF56534 10 332 8.37E-83 T 01-11-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 Pfam PF10397 Adenylosuccinate lyase C-terminus 352 429 3.1E-26 T 01-11-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 Gene3D G3DSA:1.10.275.10 1 94 3.5E-42 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 Gene3D G3DSA:1.10.40.30 351 435 2.9E-38 T 01-11-2018 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 Gene3D G3DSA:1.20.200.10 95 350 1.1E-106 T 01-11-2018 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 SMART SM00998 351 431 5.6E-41 T 01-11-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 2.0E-26 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00149 Fumarate lyase superfamily signature 263 279 2.0E-26 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00149 Fumarate lyase superfamily signature 90 108 2.0E-26 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00149 Fumarate lyase superfamily signature 218 245 2.0E-26 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 SUPERFAMILY SSF48557 3 429 9.27E-141 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 Pfam PF00206 Lyase 6 288 1.7E-75 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00145 Argininosuccinate lyase family signature 263 279 9.9E-10 T 01-11-2018 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00145 Argininosuccinate lyase family signature 89 111 9.9E-10 T 01-11-2018 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00145 Argininosuccinate lyase family signature 218 242 9.9E-10 T 01-11-2018 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 PRINTS PR00145 Argininosuccinate lyase family signature 130 150 9.9E-10 T 01-11-2018 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 ProSitePatterns PS00163 Fumarate lyases signature. 263 272 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MLA2C4_01755 4c5007c6d6eb4090e435da3be9c8b4ae 435 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 430 1.2E-182 T 01-11-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 Gene3D G3DSA:1.10.10.10 1 80 4.9E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 208 38.564 T 01-11-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 SUPERFAMILY SSF46785 7 78 5.9E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 Pfam PF02629 CoA binding domain 82 177 3.0E-30 T 01-11-2018 IPR003781 CoA-binding GO:0048037 MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 SUPERFAMILY SSF51735 82 206 5.57E-30 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 Pfam PF06971 Putative DNA-binding protein N-terminus 5 53 3.5E-18 T 01-11-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 Gene3D G3DSA:3.40.50.720 81 208 5.2E-45 T 01-11-2018 MLA2C4_01555 e854205260418ca8327bf09a4ca6ad1e 209 SMART SM00881 79 179 1.9E-19 T 01-11-2018 IPR003781 CoA-binding GO:0048037 MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 249 8.6E-55 T 01-11-2018 MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 6.4E-9 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 6.4E-9 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 6.4E-9 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.7E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 SUPERFAMILY SSF51735 3 250 2.97E-76 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 Gene3D G3DSA:3.40.50.720 1 252 3.2E-84 T 01-11-2018 MLA2C4_09435 a7f10f93a303db475289f0ea401b6c0b 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_24835 ff2cbd439218ee5fe3ba829d7f168349 301 Pfam PF00892 EamA-like transporter family 7 138 4.2E-28 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_24835 ff2cbd439218ee5fe3ba829d7f168349 301 Pfam PF00892 EamA-like transporter family 153 284 2.6E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_24835 ff2cbd439218ee5fe3ba829d7f168349 301 SUPERFAMILY SSF103481 39 142 3.66E-17 T 01-11-2018 MLA2C4_24835 ff2cbd439218ee5fe3ba829d7f168349 301 SUPERFAMILY SSF103481 201 286 1.26E-12 T 01-11-2018 MLA2C4_25650 dc1f3ccdbbce920cd909ad803eed6dc5 415 Gene3D G3DSA:1.20.1250.20 17 212 3.8E-23 T 01-11-2018 MLA2C4_25650 dc1f3ccdbbce920cd909ad803eed6dc5 415 SUPERFAMILY SSF103473 20 409 2.62E-40 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_25650 dc1f3ccdbbce920cd909ad803eed6dc5 415 Pfam PF07690 Major Facilitator Superfamily 27 364 2.3E-31 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_25650 dc1f3ccdbbce920cd909ad803eed6dc5 415 Gene3D G3DSA:1.20.1250.20 225 410 1.3E-9 T 01-11-2018 MLA2C4_11925 61733dbd578d0c3a4012edc5a1d69cf7 154 Pfam PF04471 Restriction endonuclease 42 152 1.0E-31 T 01-11-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 MLA2C4_11925 61733dbd578d0c3a4012edc5a1d69cf7 154 Gene3D G3DSA:3.40.1350.10 47 152 2.2E-8 T 01-11-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MLA2C4_11925 61733dbd578d0c3a4012edc5a1d69cf7 154 SUPERFAMILY SSF52980 47 153 7.29E-24 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 01-11-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 Gene3D G3DSA:3.30.1490.20 150 222 2.6E-29 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 348 41.496 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 SUPERFAMILY SSF52440 3 134 6.04E-35 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 290 318 - T 01-11-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 Gene3D G3DSA:3.40.50.20 1 123 7.0E-37 T 01-11-2018 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 Pfam PF01820 D-ala D-ala ligase N-terminus 5 124 9.0E-31 T 01-11-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 SUPERFAMILY SSF56059 135 350 9.02E-61 T 01-11-2018 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 Gene3D G3DSA:3.30.470.20 223 361 3.1E-50 T 01-11-2018 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 347 2.8E-115 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 Pfam PF07478 D-ala D-ala ligase C-terminus 143 344 3.8E-79 T 01-11-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_01380 0a8d2a8fc1e6ef0e3f39bbd863eb4ffa 361 PIRSF PIRSF039102 1 356 2.5E-116 T 01-11-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 643 56.073 T 01-11-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 SMART SM00437 242 510 1.6E-123 T 01-11-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 5.0E-36 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 5.0E-36 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 5.0E-36 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 5.0E-36 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 5.0E-36 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 1.3E-264 T 01-11-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Gene3D G3DSA:1.10.290.10 250 385 8.1E-168 T 01-11-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 SMART SM00493 3 103 7.7E-34 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Gene3D G3DSA:1.10.460.10 135 550 8.1E-168 T 01-11-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 SMART SM00436 104 192 3.0E-51 T 01-11-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Gene3D G3DSA:3.30.65.10 559 617 2.7E-14 T 01-11-2018 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Gene3D G3DSA:3.40.50.140 1 134 6.1E-54 T 01-11-2018 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Pfam PF01751 Toprim domain 5 113 4.4E-30 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 SUPERFAMILY SSF57783 576 613 2.72E-13 T 01-11-2018 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 656 1.3E-11 T 01-11-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 687 0.022 T 01-11-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 576 613 3.5E-14 T 01-11-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 SUPERFAMILY SSF56712 4 625 1.7E-201 T 01-11-2018 IPR023405 DNA topoisomerase, type IA, core domain MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 01-11-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Gene3D G3DSA:2.70.20.10 184 457 8.1E-168 T 01-11-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MLA2C4_20035 a4640bf002fba5f06e078b9c4f27573e 692 Pfam PF01131 DNA topoisomerase 128 547 8.2E-136 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 173 185 6.5E-21 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 217 6.5E-21 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 82 95 6.5E-21 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 120 6.5E-21 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 Gene3D G3DSA:3.90.230.10 17 264 1.1E-85 T 01-11-2018 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 Hamap MF_01974 Methionine aminopeptidase [map]. 17 264 35.774 T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 SUPERFAMILY SSF55920 14 262 2.62E-70 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 Pfam PF00557 Metallopeptidase family M24 27 254 1.3E-47 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_27730 5ad7d0f3f7290d79fa751ac92ad978e2 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 263 1.1E-89 T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_22320 1d19f721a07bbaeea5d7c29c831bc051 288 Gene3D G3DSA:1.10.3720.10 59 288 1.7E-33 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_22320 1d19f721a07bbaeea5d7c29c831bc051 288 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 23 287 3.0E-79 T 01-11-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MLA2C4_22320 1d19f721a07bbaeea5d7c29c831bc051 288 SUPERFAMILY SSF161098 19 284 1.23E-38 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_22320 1d19f721a07bbaeea5d7c29c831bc051 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 284 2.9E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 Gene3D G3DSA:2.40.10.10 59 169 3.0E-27 T 01-11-2018 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 SUPERFAMILY SSF50156 271 386 1.71E-19 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 Pfam PF13180 PDZ domain 289 386 3.5E-15 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 Gene3D G3DSA:2.30.42.10 292 390 1.1E-20 T 01-11-2018 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 SMART SM00228 289 377 4.2E-6 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 SUPERFAMILY SSF50494 69 286 3.29E-56 T 01-11-2018 IPR009003 Peptidase S1, PA clan MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 Pfam PF13365 Trypsin-like peptidase domain 104 251 1.8E-30 T 01-11-2018 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 Gene3D G3DSA:2.40.10.10 170 291 4.9E-38 T 01-11-2018 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 PRINTS PR00834 HtrA/DegQ protease family signature 178 202 7.0E-36 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 7.0E-36 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 7.0E-36 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 7.0E-36 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 PRINTS PR00834 HtrA/DegQ protease family signature 335 347 7.0E-36 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_28325 cca9655785cb5f98b67adec1dda641c0 391 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 7.0E-36 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_14790 8307bf88566cbb9158c1be4234608e8e 144 Pfam PF13673 Acetyltransferase (GNAT) domain 42 142 4.8E-19 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14790 8307bf88566cbb9158c1be4234608e8e 144 Gene3D G3DSA:3.40.630.30 2 142 4.0E-41 T 01-11-2018 MLA2C4_14790 8307bf88566cbb9158c1be4234608e8e 144 SUPERFAMILY SSF55729 9 143 1.29E-33 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21190 6176115c832569b9254bfbc4bbb29a1a 268 SUPERFAMILY SSF56784 1 254 1.05E-53 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_21190 6176115c832569b9254bfbc4bbb29a1a 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 232 1.5E-25 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_21190 6176115c832569b9254bfbc4bbb29a1a 268 Gene3D G3DSA:3.40.50.1000 5 257 1.5E-53 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_21190 6176115c832569b9254bfbc4bbb29a1a 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 5.8E-48 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_21190 6176115c832569b9254bfbc4bbb29a1a 268 Gene3D G3DSA:3.30.1240.10 82 188 1.5E-53 T 01-11-2018 MLA2C4_21190 6176115c832569b9254bfbc4bbb29a1a 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 257 1.5E-49 T 01-11-2018 MLA2C4_16750 aa9ad8597435a92ca380d96cc0aeaf23 327 Gene3D G3DSA:3.90.1200.10 116 298 6.0E-9 T 01-11-2018 MLA2C4_16750 aa9ad8597435a92ca380d96cc0aeaf23 327 SUPERFAMILY SSF56112 31 284 4.23E-22 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_16750 aa9ad8597435a92ca380d96cc0aeaf23 327 Pfam PF01636 Phosphotransferase enzyme family 63 254 4.0E-9 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 Pfam PF00890 FAD binding domain 5 369 1.2E-86 T 01-11-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 SUPERFAMILY SSF51905 3 390 1.09E-57 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 354 3.0E-5 T 01-11-2018 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.0E-5 T 01-11-2018 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 Pfam PF02910 Fumarate reductase flavoprotein C-term 412 494 5.2E-14 T 01-11-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 Gene3D G3DSA:1.20.58.100 396 507 3.2E-24 T 01-11-2018 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 Gene3D G3DSA:3.90.700.10 227 324 6.7E-136 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 Gene3D G3DSA:3.50.50.60 8 376 6.7E-136 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 490 1.7E-163 T 01-11-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 SUPERFAMILY SSF46977 410 495 5.76E-24 T 01-11-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23100 2f6e0f401f6dc22dc70df01caf7f3590 509 SUPERFAMILY SSF56425 219 329 1.24E-33 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_10300 4d049b725adb26f80a78c4fac8ed9944 156 Pfam PF00583 Acetyltransferase (GNAT) family 36 129 1.8E-17 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10300 4d049b725adb26f80a78c4fac8ed9944 156 Gene3D G3DSA:1.10.287.900 1 41 1.2E-5 T 01-11-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117|MetaCyc: PWY-6922 MLA2C4_10300 4d049b725adb26f80a78c4fac8ed9944 156 SUPERFAMILY SSF55729 1 142 6.62E-28 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10300 4d049b725adb26f80a78c4fac8ed9944 156 Gene3D G3DSA:3.40.630.30 45 146 3.2E-24 T 01-11-2018 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 Gene3D G3DSA:3.40.50.300 12 444 3.9E-208 T 01-11-2018 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 334 345 - T 01-11-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 Pfam PF01268 Formate--tetrahydrofolate ligase 8 562 9.6E-274 T 01-11-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 SUPERFAMILY SSF52540 10 560 1.16E-249 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 109 119 - T 01-11-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 Gene3D G3DSA:3.10.410.10 449 538 1.3E-36 T 01-11-2018 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 Gene3D G3DSA:3.30.1510.10 135 253 3.9E-208 T 01-11-2018 MLA2C4_10720 a5857d437fc5c1799d6d3533e2be9c8c 562 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 562 49.352 T 01-11-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MLA2C4_05130 8d3fe1c78ef4dcf1d5f03790f444dc86 34 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 33 4.9E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_05130 8d3fe1c78ef4dcf1d5f03790f444dc86 34 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 10 31 8.5E-13 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 Pfam PF02378 Phosphotransferase system, EIIC 9 339 1.1E-78 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 Gene3D G3DSA:3.30.1360.60 423 497 4.6E-25 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 436 453 - T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 SUPERFAMILY SSF55604 425 496 1.96E-19 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 Pfam PF00367 phosphotransferase system, EIIB 427 458 3.5E-13 T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 396 483 2.2E-20 T 01-11-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MLA2C4_02600 2462762e1c71c8fb86554ebeeef73887 497 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 494 2.2E-183 T 01-11-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 MLA2C4_18075 9ef63b25898b54a9f0effcc842e3ab44 345 Pfam PF13170 Protein of unknown function (DUF4003) 32 325 1.6E-102 T 01-11-2018 IPR025062 Protein of unknown function DUF4003 MLA2C4_28115 a9107c98c3c21545710b1c3b4d81994c 484 Pfam PF01943 Polysaccharide biosynthesis protein 6 271 1.9E-19 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 13 446 2.8E-152 T 01-11-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Gene3D G3DSA:3.40.50.970 381 580 8.8E-66 T 01-11-2018 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Gene3D G3DSA:3.40.50.970 1 175 3.6E-68 T 01-11-2018 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 SUPERFAMILY SSF52518 387 575 7.94E-33 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 PIRSF PIRSF004983 2 578 2.1E-214 T 01-11-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 5 571 35.99 T 01-11-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 SUPERFAMILY SSF52467 168 375 3.47E-9 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Pfam PF16582 Middle domain of thiamine pyrophosphate 222 403 2.8E-16 T 01-11-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 176 1.1E-37 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 SUPERFAMILY SSF52518 14 180 8.34E-35 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 438 553 3.6E-10 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_25270 aa2494a7dcd0f6a834d451b99c4220f7 584 Gene3D G3DSA:3.40.50.1220 200 380 6.0E-56 T 01-11-2018 MLA2C4_16975 e945adf3a8860a2c7feb502f8047ae6b 66 SMART SM00530 5 60 5.3E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_16975 e945adf3a8860a2c7feb502f8047ae6b 66 Pfam PF01381 Helix-turn-helix 10 59 1.2E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_16975 e945adf3a8860a2c7feb502f8047ae6b 66 Gene3D G3DSA:1.10.260.40 1 66 6.4E-28 T 01-11-2018 MLA2C4_16975 e945adf3a8860a2c7feb502f8047ae6b 66 SUPERFAMILY SSF47413 2 62 1.64E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_24195 44ce1192b19ceef7edf635d8a6060983 100 Pfam PF14154 Domain of unknown function (DUF4306) 6 92 1.2E-36 T 01-11-2018 IPR025440 Protein of unknown function DUF4306 MLA2C4_24195 44ce1192b19ceef7edf635d8a6060983 100 PIRSF PIRSF007103 1 100 2.9E-50 T 01-11-2018 IPR016508 Uncharacterised conserved protein UCP007103 MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 SUPERFAMILY SSF75138 72 185 3.01E-29 T 01-11-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 SUPERFAMILY SSF46785 5 54 1.91E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Pfam PF07085 DRTGG domain 76 178 4.1E-30 T 01-11-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Pfam PF03061 Thioesterase superfamily 352 425 7.3E-10 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 SUPERFAMILY SSF54637 335 436 3.44E-16 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Gene3D G3DSA:3.10.580.10 186 314 2.8E-26 T 01-11-2018 MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 SMART SM00116 259 307 5.0E-9 T 01-11-2018 IPR000644 CBS domain MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 SMART SM00116 200 248 0.078 T 01-11-2018 IPR000644 CBS domain MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Pfam PF00571 CBS domain 191 246 1.6E-6 T 01-11-2018 IPR000644 CBS domain MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Pfam PF00571 CBS domain 254 307 9.0E-10 T 01-11-2018 IPR000644 CBS domain MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Gene3D G3DSA:3.40.1390.20 71 178 4.5E-26 T 01-11-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Gene3D G3DSA:3.10.129.10 318 433 1.4E-9 T 01-11-2018 MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 SUPERFAMILY SSF54631 182 306 1.89E-31 T 01-11-2018 MLA2C4_23955 9f4350ace9749ccf0ff272f945bc210c 437 Gene3D G3DSA:1.10.10.10 5 70 3.4E-6 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_02675 634ceb812b83eee5e2b1bc1c8e6c0ddc 301 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 1.4E-17 T 01-11-2018 IPR013549 Domain of unknown function DUF1731 MLA2C4_02675 634ceb812b83eee5e2b1bc1c8e6c0ddc 301 SUPERFAMILY SSF51735 2 288 4.68E-43 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_02675 634ceb812b83eee5e2b1bc1c8e6c0ddc 301 Gene3D G3DSA:3.40.50.720 2 300 3.2E-73 T 01-11-2018 MLA2C4_02675 634ceb812b83eee5e2b1bc1c8e6c0ddc 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 2.8E-19 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_02675 634ceb812b83eee5e2b1bc1c8e6c0ddc 301 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 1.1E-108 T 01-11-2018 IPR010099 Epimerase family protein SDR39U1 MLA2C4_15585 f812c0b435088b539b76b7a3784753bc 359 SUPERFAMILY SSF52499 185 337 4.71E-47 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_15585 f812c0b435088b539b76b7a3784753bc 359 Gene3D G3DSA:3.40.630.30 1 173 4.4E-48 T 01-11-2018 MLA2C4_15585 f812c0b435088b539b76b7a3784753bc 359 Pfam PF00857 Isochorismatase family 187 327 3.6E-40 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_15585 f812c0b435088b539b76b7a3784753bc 359 Gene3D G3DSA:3.40.50.850 174 353 7.8E-49 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_15585 f812c0b435088b539b76b7a3784753bc 359 Pfam PF13523 Acetyltransferase (GNAT) domain 15 157 2.2E-29 T 01-11-2018 MLA2C4_15585 f812c0b435088b539b76b7a3784753bc 359 SUPERFAMILY SSF55729 3 176 2.3E-39 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_07445 661b66d4b82b534aaa817a12fb63ea2a 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 198 35.134 T 01-11-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MLA2C4_07445 661b66d4b82b534aaa817a12fb63ea2a 209 PIRSF PIRSF000495 1 201 4.5E-70 T 01-11-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MLA2C4_07445 661b66d4b82b534aaa817a12fb63ea2a 209 SUPERFAMILY SSF52317 2 198 4.03E-54 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_07445 661b66d4b82b534aaa817a12fb63ea2a 209 Pfam PF00117 Glutamine amidotransferase class-I 4 195 4.0E-20 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_07445 661b66d4b82b534aaa817a12fb63ea2a 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 196 4.1E-71 T 01-11-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MLA2C4_07445 661b66d4b82b534aaa817a12fb63ea2a 209 Gene3D G3DSA:3.40.50.880 1 207 3.0E-70 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 Pfam PF01381 Helix-turn-helix 31 83 9.7E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 SUPERFAMILY SSF51182 70 202 1.03E-24 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 SMART SM00530 30 85 3.6E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 Gene3D G3DSA:1.10.260.40 19 94 1.7E-18 T 01-11-2018 MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 SUPERFAMILY SSF47413 20 91 7.04E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 Gene3D G3DSA:2.60.120.10 110 204 9.6E-29 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_12565 9a240e5bbd6ce371b13851b5486dbc85 204 Pfam PF07883 Cupin domain 136 194 4.6E-11 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_08850 a15e1a671a778229e3782863cb3b298b 556 SUPERFAMILY SSF161098 294 551 1.12E-41 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_08850 a15e1a671a778229e3782863cb3b298b 556 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 369 552 1.4E-13 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_08850 a15e1a671a778229e3782863cb3b298b 556 SUPERFAMILY SSF161098 10 271 6.54E-39 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_08850 a15e1a671a778229e3782863cb3b298b 556 Gene3D G3DSA:1.10.3720.10 11 275 1.2E-44 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_08850 a15e1a671a778229e3782863cb3b298b 556 Gene3D G3DSA:1.10.3720.10 291 554 5.3E-39 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 144 4.2E-65 T 01-11-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 Gene3D G3DSA:3.30.1550.10 5 74 3.5E-34 T 01-11-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 2.0E-25 T 01-11-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 SUPERFAMILY SSF54747 6 75 1.96E-30 T 01-11-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 4.0E-16 T 01-11-2018 MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 SMART SM00649 12 143 2.3E-87 T 01-11-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 SUPERFAMILY SSF46906 70 143 4.06E-27 T 01-11-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.612 T 01-11-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 2.7E-31 T 01-11-2018 IPR020784 Ribosomal protein L11, N-terminal MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 Gene3D G3DSA:1.10.10.250 75 143 3.0E-29 T 01-11-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MLA2C4_00605 401d11e52da888da41d007a885365d4a 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 01-11-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_25840 f0457bf5a0b57c6857cf97bfa28f6d6c 102 Pfam PF06265 Protein of unknown function (DUF1027) 15 98 2.9E-38 T 01-11-2018 IPR009370 Protein of unknown function DUF1027 MLA2C4_25840 f0457bf5a0b57c6857cf97bfa28f6d6c 102 Gene3D G3DSA:3.50.4.20 1 102 7.4E-43 T 01-11-2018 IPR038141 YutD-like superfamily MLA2C4_25840 f0457bf5a0b57c6857cf97bfa28f6d6c 102 PIRSF PIRSF012565 1 102 6.7E-51 T 01-11-2018 IPR009370 Protein of unknown function DUF1027 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 42.734 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 Gene3D G3DSA:1.10.560.10 7 518 5.8E-236 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 SUPERFAMILY SSF48592 5 518 2.82E-80 T 01-11-2018 IPR027413 GroEL-like equatorial domain superfamily MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 6.7E-259 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 Gene3D G3DSA:3.30.260.10 137 408 5.8E-236 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 PRINTS PR00298 60kDa chaperonin signature 82 109 4.7E-73 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 PRINTS PR00298 60kDa chaperonin signature 348 373 4.7E-73 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 PRINTS PR00298 60kDa chaperonin signature 26 52 4.7E-73 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 PRINTS PR00298 60kDa chaperonin signature 396 417 4.7E-73 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 PRINTS PR00298 60kDa chaperonin signature 266 289 4.7E-73 T 01-11-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 SUPERFAMILY SSF52029 183 374 3.89E-86 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 3.7E-103 T 01-11-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 01-11-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 SUPERFAMILY SSF54849 136 204 1.03E-25 T 01-11-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MLA2C4_01575 12e36b9a0085e5b125c3f3901b711273 544 Gene3D G3DSA:3.50.7.10 171 377 5.8E-236 T 01-11-2018 IPR027409 GroEL-like apical domain superfamily MLA2C4_16930 7286ba415f7a431f0f1223b00e98fd1f 481 SUPERFAMILY SSF143985 221 340 1.05E-30 T 01-11-2018 IPR038054 L,D-transpeptidase central domain-like superfamily MLA2C4_16930 7286ba415f7a431f0f1223b00e98fd1f 481 Gene3D G3DSA:2.40.440.10 355 481 1.3E-35 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_16930 7286ba415f7a431f0f1223b00e98fd1f 481 Gene3D G3DSA:1.10.269.20 220 340 2.3E-18 T 01-11-2018 IPR038054 L,D-transpeptidase central domain-like superfamily MLA2C4_16930 7286ba415f7a431f0f1223b00e98fd1f 481 Pfam PF12229 Putative peptidoglycan binding domain 225 327 2.2E-11 T 01-11-2018 IPR022029 Putative peptidoglycan binding domain MLA2C4_16930 7286ba415f7a431f0f1223b00e98fd1f 481 SUPERFAMILY SSF141523 353 481 7.59E-29 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_16930 7286ba415f7a431f0f1223b00e98fd1f 481 Pfam PF03734 L,D-transpeptidase catalytic domain 356 480 1.2E-14 T 01-11-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MLA2C4_06560 96136a213a59bebd9d4fbabbcd55af71 162 Pfam PF00583 Acetyltransferase (GNAT) family 43 134 2.8E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_06560 96136a213a59bebd9d4fbabbcd55af71 162 SUPERFAMILY SSF55729 4 134 3.06E-14 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_06560 96136a213a59bebd9d4fbabbcd55af71 162 Gene3D G3DSA:3.40.630.30 3 141 3.9E-12 T 01-11-2018 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 PIRSF PIRSF002599 1 65 3.1E-24 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 SMART SM00357 2 65 1.7E-30 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 SUPERFAMILY SSF50249 1 64 4.63E-24 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 3 18 1.5E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 23 32 1.5E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 38 56 1.5E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 1.0E-30 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 01-11-2018 IPR019844 Cold-shock conserved site MLA2C4_08370 ed6a91e3e4f24ef594cc16cead55dd1e 65 Gene3D G3DSA:2.40.50.140 1 64 3.1E-30 T 01-11-2018 MLA2C4_18810 974ab69e4ec67ba63a10aef8c8486ede 49 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 49 4.3E-30 T 01-11-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 MLA2C4_18810 974ab69e4ec67ba63a10aef8c8486ede 49 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 49 22.044 T 01-11-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 MLA2C4_18810 974ab69e4ec67ba63a10aef8c8486ede 49 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 38 5.0E-13 T 01-11-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 MLA2C4_18810 974ab69e4ec67ba63a10aef8c8486ede 49 Pfam PF08175 Small acid-soluble spore protein O family 3 49 7.1E-25 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Gene3D G3DSA:2.60.40.2560 573 654 2.9E-13 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 01-11-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 SUPERFAMILY SSF54184 508 565 8.37E-5 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Pfam PF00069 Protein kinase domain 11 264 5.4E-55 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 SUPERFAMILY SSF56112 7 269 2.7E-84 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Gene3D G3DSA:3.30.10.20 366 432 8.1E-16 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Gene3D G3DSA:3.30.200.20 1 90 2.0E-33 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Gene3D G3DSA:3.30.10.20 433 501 2.2E-9 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 SMART SM00220 11 271 4.8E-68 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Gene3D G3DSA:1.10.510.10 92 279 2.4E-53 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Gene3D G3DSA:3.30.10.20 507 569 1.6E-16 T 01-11-2018 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 01-11-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Pfam PF03793 PASTA domain 369 431 3.4E-14 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Pfam PF03793 PASTA domain 438 499 5.2E-10 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 Pfam PF03793 PASTA domain 508 565 1.5E-14 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 SMART SM00740 365 432 5.5E-14 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 SMART SM00740 433 499 6.8E-4 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20185 3853f7aa96e6fa368ed2824e8d5f2ce6 657 SMART SM00740 500 566 2.8E-14 T 01-11-2018 IPR005543 PASTA domain MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 SUPERFAMILY SSF143437 4 174 4.01E-53 T 01-11-2018 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 Gene3D G3DSA:3.40.50.620 176 404 4.2E-84 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 163.927 T 01-11-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 176 371 3.7E-70 T 01-11-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 SMART SM00981 75 166 2.4E-19 T 01-11-2018 IPR004114 THUMP domain GO:0003723 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 373 1.7E-129 T 01-11-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 SUPERFAMILY SSF52402 176 380 6.62E-54 T 01-11-2018 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 Pfam PF02926 THUMP domain 35 163 1.0E-18 T 01-11-2018 IPR004114 THUMP domain GO:0003723 MLA2C4_24145 c8235bfb41b4b5c0e88917d6d326a200 404 Gene3D G3DSA:3.30.2130.30 1 175 3.1E-67 T 01-11-2018 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 262 8.5E-75 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 SUPERFAMILY SSF53927 5 262 3.61E-77 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 Pfam PF02634 FdhD/NarQ family 26 261 2.5E-80 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 PIRSF PIRSF015626 1 264 8.1E-79 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 Gene3D G3DSA:3.40.140.10 116 265 5.4E-48 T 01-11-2018 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 262 32.394 T 01-11-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MLA2C4_18530 f10e736fd0f41a764a5992b34708bfeb 265 Gene3D G3DSA:3.10.20.10 28 110 1.3E-13 T 01-11-2018 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Pfam PF01627 Hpt domain 4 103 5.0E-17 T 01-11-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Pfam PF07194 P2 response regulator binding domain 148 225 2.2E-20 T 01-11-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SUPERFAMILY SSF47384 287 347 3.3E-11 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Gene3D G3DSA:3.30.70.1110 144 226 4.2E-18 T 01-11-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SMART SM01231 286 346 2.8E-11 T 01-11-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Gene3D G3DSA:1.20.120.160 2 143 1.1E-35 T 01-11-2018 IPR036641 HPT domain superfamily GO:0000160 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Gene3D G3DSA:3.30.565.10 347 533 2.5E-60 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 533 1.8E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Pfam PF01584 CheW-like domain 539 670 1.8E-24 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Gene3D G3DSA:2.30.30.40 534 666 2.7E-36 T 01-11-2018 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Gene3D G3DSA:2.40.50.180 557 625 2.7E-36 T 01-11-2018 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SMART SM00387 391 534 6.0E-26 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_08530 de57ebd83880424d65387872875d7735 670 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 488 6.9E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 531 6.9E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 512 6.9E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 450 6.9E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SUPERFAMILY SSF50341 533 670 4.19E-30 T 01-11-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SUPERFAMILY SSF55874 348 532 8.25E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SUPERFAMILY SSF55052 147 225 2.88E-19 T 01-11-2018 IPR035891 CheY-binding domain of CheA MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Gene3D G3DSA:1.10.287.560 286 346 1.4E-11 T 01-11-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SMART SM00073 2 99 2.2E-30 T 01-11-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SMART SM00260 526 670 2.4E-29 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 287 344 5.7E-7 T 01-11-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MLA2C4_08530 de57ebd83880424d65387872875d7735 670 SUPERFAMILY SSF47226 3 123 5.23E-31 T 01-11-2018 IPR036641 HPT domain superfamily GO:0000160 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 Pfam PF13432 Tetratricopeptide repeat 156 217 3.8E-7 T 01-11-2018 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 Gene3D G3DSA:1.25.40.10 7 131 6.8E-13 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 SMART SM00028 88 121 67.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 SMART SM00028 21 54 34.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 SMART SM00028 184 217 0.0048 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 SUPERFAMILY SSF48452 152 319 4.17E-21 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 Gene3D G3DSA:1.25.40.10 151 326 2.2E-22 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_26685 f1fc0e93371cb85917c1f71b2c43cabc 503 SUPERFAMILY SSF48452 19 133 4.3E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_00685 e4f8ed7e0459f9ad9bdf9874e879add0 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 20.572 T 01-11-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00685 e4f8ed7e0459f9ad9bdf9874e879add0 96 SUPERFAMILY SSF54189 1 91 1.73E-30 T 01-11-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00685 e4f8ed7e0459f9ad9bdf9874e879add0 96 Pfam PF00276 Ribosomal protein L23 6 88 3.9E-31 T 01-11-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00685 e4f8ed7e0459f9ad9bdf9874e879add0 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 01-11-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00685 e4f8ed7e0459f9ad9bdf9874e879add0 96 Gene3D G3DSA:3.30.70.330 1 96 1.6E-31 T 01-11-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MLA2C4_08575 bbe55dc8a901b89bc4c1cc2361d7ad5b 287 SUPERFAMILY SSF64518 1 287 1.57E-48 T 01-11-2018 MLA2C4_08575 bbe55dc8a901b89bc4c1cc2361d7ad5b 287 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 176 4.2E-51 T 01-11-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 MLA2C4_08575 bbe55dc8a901b89bc4c1cc2361d7ad5b 287 Gene3D G3DSA:1.20.1330.10 39 234 1.2E-42 T 01-11-2018 MLA2C4_08575 bbe55dc8a901b89bc4c1cc2361d7ad5b 287 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 2.2E-10 T 01-11-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MLA2C4_08575 bbe55dc8a901b89bc4c1cc2361d7ad5b 287 Pfam PF00700 Bacterial flagellin C-terminal helical region 213 287 1.7E-5 T 01-11-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 Pfam PF00271 Helicase conserved C-terminal domain 311 408 3.5E-9 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 SMART SM00487 103 285 1.1E-15 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 Pfam PF04851 Type III restriction enzyme, res subunit 107 254 1.7E-9 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 Gene3D G3DSA:3.40.50.300 293 447 7.1E-21 T 01-11-2018 MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 SUPERFAMILY SSF52540 118 422 7.59E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 Gene3D G3DSA:3.40.50.300 108 271 1.1E-21 T 01-11-2018 MLA2C4_26865 d44e66fa1d91cf166a781380d885c9f3 449 SMART SM00490 329 410 7.9E-11 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.5 T 01-11-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 SUPERFAMILY SSF46946 2 120 8.37E-45 T 01-11-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 01-11-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 Gene3D G3DSA:1.10.8.50 1 71 7.3E-29 T 01-11-2018 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.9E-33 T 01-11-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 Gene3D G3DSA:4.10.910.10 72 121 6.3E-25 T 01-11-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.2E-52 T 01-11-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00800 63efbca3aa52f55d00d7b16236f64433 121 PIRSF PIRSF002134 1 121 2.0E-41 T 01-11-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 Gene3D G3DSA:3.50.50.60 117 240 4.9E-116 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 3.6E-121 T 01-11-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 1.7E-50 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 SUPERFAMILY SSF51905 4 302 1.13E-57 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 01-11-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.3E-37 T 01-11-2018 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.3E-37 T 01-11-2018 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.3E-37 T 01-11-2018 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.3E-37 T 01-11-2018 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.3E-37 T 01-11-2018 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 3.8E-71 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_26680 6cc975071d3c823a0c39727a3cb40d3d 318 Gene3D G3DSA:3.50.50.60 8 301 4.9E-116 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 Gene3D G3DSA:2.30.40.10 13 377 6.3E-124 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 Pfam PF01979 Amidohydrolase family 49 377 2.6E-24 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 42 376 4.2E-96 T 01-11-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 PIRSF PIRSF038994 11 383 3.9E-120 T 01-11-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 SUPERFAMILY SSF51338 1 383 5.4E-14 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 SUPERFAMILY SSF51556 53 350 6.81E-99 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_09295 bad991e0de3395e0fd959238a9436ac0 387 Gene3D G3DSA:3.20.20.140 53 350 6.3E-124 T 01-11-2018 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 Gene3D G3DSA:3.90.190.20 301 433 4.7E-35 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 Pfam PF08245 Mur ligase middle domain 47 273 5.1E-14 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 428 2.3E-129 T 01-11-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 Gene3D G3DSA:3.40.1190.10 3 299 2.1E-100 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 PIRSF PIRSF001563 1 433 3.7E-158 T 01-11-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 01-11-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 SUPERFAMILY SSF53244 301 431 4.94E-31 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 SUPERFAMILY SSF53623 3 299 1.01E-95 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 01-11-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MLA2C4_23235 2c8da55bb3f24badd9e9d8bd3bdcbfef 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 372 1.3E-11 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 36.991 T 01-11-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 1.1E-15 T 01-11-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 SUPERFAMILY SSF47648 1 67 1.44E-15 T 01-11-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 Pfam PF00591 Glycosyl transferase family, a/b domain 73 323 1.8E-90 T 01-11-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 330 1.2E-115 T 01-11-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 SUPERFAMILY SSF52418 73 337 5.1E-90 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 Gene3D G3DSA:1.20.970.10 3 67 4.0E-19 T 01-11-2018 MLA2C4_06500 25bee1ceac9857a342e6b0154f6ffa50 341 Gene3D G3DSA:3.40.1030.10 70 338 3.4E-102 T 01-11-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_24320 f5e61ec8fbb12b2ce96db666ab01fc93 108 SUPERFAMILY SSF52833 1 104 4.43E-9 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_24320 f5e61ec8fbb12b2ce96db666ab01fc93 108 Gene3D G3DSA:3.40.30.10 1 107 1.9E-39 T 01-11-2018 MLA2C4_24320 f5e61ec8fbb12b2ce96db666ab01fc93 108 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 5 104 8.1E-39 T 01-11-2018 IPR022551 Protein of unknown function DUF2847 MLA2C4_24320 f5e61ec8fbb12b2ce96db666ab01fc93 108 Pfam PF11009 Protein of unknown function (DUF2847) 5 103 7.8E-37 T 01-11-2018 IPR022551 Protein of unknown function DUF2847 MLA2C4_16965 189d715e0915cdb47f693d65c7c79b9c 513 Gene3D G3DSA:3.40.710.10 41 369 8.6E-78 T 01-11-2018 MLA2C4_16965 189d715e0915cdb47f693d65c7c79b9c 513 SUPERFAMILY SSF56601 46 378 1.82E-72 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_16965 189d715e0915cdb47f693d65c7c79b9c 513 Pfam PF00144 Beta-lactamase 61 375 1.7E-53 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 Pfam PF07687 Peptidase dimerisation domain 188 309 9.4E-31 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 Gene3D G3DSA:3.40.630.10 37 420 1.1E-91 T 01-11-2018 MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 SUPERFAMILY SSF55031 215 308 3.29E-11 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 Pfam PF01546 Peptidase family M20/M25/M40 86 417 2.7E-30 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 Gene3D G3DSA:3.30.70.360 191 333 1.1E-91 T 01-11-2018 MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 SUPERFAMILY SSF53187 6 420 4.02E-61 T 01-11-2018 MLA2C4_02575 3dbe97c66ec835b0ef4fb40004177c3f 424 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 411 9.3E-117 T 01-11-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase MLA2C4_19585 4c7a9c981c8effc52b6e3b46cf8ffcd7 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 138 2.8E-33 T 01-11-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_19585 4c7a9c981c8effc52b6e3b46cf8ffcd7 354 Gene3D G3DSA:3.40.50.2000 162 318 3.1E-85 T 01-11-2018 MLA2C4_19585 4c7a9c981c8effc52b6e3b46cf8ffcd7 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 353 26.265 T 01-11-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_19585 4c7a9c981c8effc52b6e3b46cf8ffcd7 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 334 1.3E-26 T 01-11-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MLA2C4_19585 4c7a9c981c8effc52b6e3b46cf8ffcd7 354 Gene3D G3DSA:3.40.50.2000 6 161 3.1E-85 T 01-11-2018 MLA2C4_19585 4c7a9c981c8effc52b6e3b46cf8ffcd7 354 SUPERFAMILY SSF53756 3 332 4.19E-87 T 01-11-2018 MLA2C4_04270 8153c40a009ee6dd60664e77fcd831da 87 Pfam PF02583 Metal-sensitive transcriptional repressor 4 84 1.4E-25 T 01-11-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MLA2C4_04270 8153c40a009ee6dd60664e77fcd831da 87 Gene3D G3DSA:1.20.58.1000 2 86 6.2E-24 T 01-11-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily MLA2C4_15795 3154cb21762de01672960f88b016b593 160 Pfam PF11188 Protein of unknown function (DUF2975) 31 160 2.4E-40 T 01-11-2018 IPR021354 Protein of unknown function DUF2975 MLA2C4_01630 5f1bed4d1abe8e69bef996d0074f2759 243 Gene3D G3DSA:3.40.30.10 1 209 4.1E-74 T 01-11-2018 MLA2C4_01630 5f1bed4d1abe8e69bef996d0074f2759 243 SUPERFAMILY SSF52833 1 212 1.17E-44 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_01630 5f1bed4d1abe8e69bef996d0074f2759 243 Pfam PF01323 DSBA-like thioredoxin domain 2 206 3.0E-42 T 01-11-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MLA2C4_09320 2f83cdeb91fdd6ec8a09de70dd60585d 277 Gene3D G3DSA:3.80.10.10 3 122 4.6E-13 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_09320 2f83cdeb91fdd6ec8a09de70dd60585d 277 Gene3D G3DSA:3.80.10.10 123 245 3.2E-11 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_09320 2f83cdeb91fdd6ec8a09de70dd60585d 277 SUPERFAMILY SSF52058 17 237 9.86E-23 T 01-11-2018 MLA2C4_09320 2f83cdeb91fdd6ec8a09de70dd60585d 277 Pfam PF13306 Leucine rich repeats (6 copies) 167 235 0.0098 T 01-11-2018 IPR026906 Leucine rich repeat 5 MLA2C4_09320 2f83cdeb91fdd6ec8a09de70dd60585d 277 Pfam PF13306 Leucine rich repeats (6 copies) 18 119 0.0036 T 01-11-2018 IPR026906 Leucine rich repeat 5 MLA2C4_24175 d4d3f28b8f74d208e151af616229acd5 159 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 01-11-2018 IPR000614 Free Met sulfoxide reductase conserved site MLA2C4_24175 d4d3f28b8f74d208e151af616229acd5 159 SUPERFAMILY SSF55781 10 156 2.58E-46 T 01-11-2018 MLA2C4_24175 d4d3f28b8f74d208e151af616229acd5 159 Pfam PF13185 GAF domain 50 154 6.1E-12 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_24175 d4d3f28b8f74d208e151af616229acd5 159 Gene3D G3DSA:3.30.450.40 3 159 2.2E-67 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_14350 028e0b83ebdd821d573be7df7c009bcc 175 Pfam PF13302 Acetyltransferase (GNAT) domain 3 143 1.5E-19 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14350 028e0b83ebdd821d573be7df7c009bcc 175 Gene3D G3DSA:3.40.630.30 1 170 1.1E-27 T 01-11-2018 MLA2C4_14350 028e0b83ebdd821d573be7df7c009bcc 175 SUPERFAMILY SSF55729 3 155 3.31E-29 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_07815 0a27d755ee848f5c17cab51cc7e88382 353 Pfam PF14493 Helix-turn-helix domain 257 344 6.5E-23 T 01-11-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MLA2C4_07815 0a27d755ee848f5c17cab51cc7e88382 353 PIRSF PIRSF021350 1 353 1.4E-131 T 01-11-2018 IPR008308 Uncharacterised conserved protein UCP021350 MLA2C4_23815 fb0002503e989ef5971af666d59fd904 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 29.672 T 01-11-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MLA2C4_23815 fb0002503e989ef5971af666d59fd904 200 Gene3D G3DSA:3.40.50.300 1 198 1.2E-79 T 01-11-2018 MLA2C4_23815 fb0002503e989ef5971af666d59fd904 200 Pfam PF01121 Dephospho-CoA kinase 4 182 2.2E-68 T 01-11-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MLA2C4_23815 fb0002503e989ef5971af666d59fd904 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 3.8E-69 T 01-11-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MLA2C4_23815 fb0002503e989ef5971af666d59fd904 200 SUPERFAMILY SSF52540 1 193 4.28E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 Gene3D G3DSA:3.30.70.100 2 99 3.7E-29 T 01-11-2018 MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 Gene3D G3DSA:3.40.250.10 104 253 3.2E-45 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 Pfam PF00581 Rhodanese-like domain 118 212 4.7E-11 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 269 39.316 T 01-11-2018 IPR020936 Uncharacterised protein family UPF0176 MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 SMART SM00450 117 218 1.6E-18 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 Pfam PF12368 Rhodanase C-terminal 224 290 2.0E-14 T 01-11-2018 IPR022111 Rhodanase, C-terminal MLA2C4_09575 962df20e7f8f3c0717831620ccf6041c 319 SUPERFAMILY SSF52821 90 248 4.12E-36 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_16045 94ddab2489c4b300574fe62ffc1e7ae2 146 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 9.0E-42 T 01-11-2018 IPR003791 Protein of unknown function UPF0178 MLA2C4_16045 94ddab2489c4b300574fe62ffc1e7ae2 146 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 146 28.45 T 01-11-2018 IPR003791 Protein of unknown function UPF0178 MLA2C4_16005 604018660562103f9fe6a073b03dd74e 313 Gene3D G3DSA:3.40.710.10 2 301 6.6E-69 T 01-11-2018 MLA2C4_16005 604018660562103f9fe6a073b03dd74e 313 SUPERFAMILY SSF56601 14 311 5.83E-71 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_16005 604018660562103f9fe6a073b03dd74e 313 Pfam PF00144 Beta-lactamase 22 290 7.5E-28 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_09085 54ac731369eca7bf4791bf9a4edb71a0 366 Pfam PF07730 Histidine kinase 177 243 6.6E-15 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_09085 54ac731369eca7bf4791bf9a4edb71a0 366 Gene3D G3DSA:3.30.565.10 249 365 5.3E-19 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09085 54ac731369eca7bf4791bf9a4edb71a0 366 SUPERFAMILY SSF55874 256 366 2.15E-11 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 Pfam PF06463 Molybdenum Cofactor Synthesis C 193 318 7.4E-37 T 01-11-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 Gene3D G3DSA:3.20.20.70 5 340 9.0E-104 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 Pfam PF04055 Radical SAM superfamily 20 185 6.5E-28 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 SUPERFAMILY SSF102114 9 310 9.68E-78 T 01-11-2018 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 8 340 2.1E-117 T 01-11-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 SMART SM00729 16 224 3.0E-9 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 Pfam PF13353 4Fe-4S single cluster domain 23 130 1.1E-8 T 01-11-2018 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 7 340 40.286 T 01-11-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18525 f362fac19a1cb76442301f63d415ebce 340 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 22 33 - T 01-11-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_20905 626fe5bbe68e807fef9a2d9828aa9a6a 375 Pfam PF01385 Probable transposase 169 275 7.8E-26 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_20905 626fe5bbe68e807fef9a2d9828aa9a6a 375 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 316 1.4E-13 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_20905 626fe5bbe68e807fef9a2d9828aa9a6a 375 Pfam PF07282 Putative transposase DNA-binding domain 289 359 1.6E-23 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_20905 626fe5bbe68e807fef9a2d9828aa9a6a 375 Pfam PF12323 Helix-turn-helix domain 4 48 4.4E-18 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 Pfam PF00072 Response regulator receiver domain 5 114 7.6E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 SMART SM00448 3 114 4.6E-48 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 SMART SM00862 156 232 2.8E-29 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 3.6E-30 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 SUPERFAMILY SSF52172 2 128 5.55E-44 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 SUPERFAMILY SSF46894 133 233 8.22E-31 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 Gene3D G3DSA:1.10.10.10 141 238 3.0E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23840 7479341b352a2c6345bcf65926fc72ce 239 Gene3D G3DSA:3.40.50.2300 1 140 3.5E-41 T 01-11-2018 MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 Gene3D G3DSA:1.10.10.10 127 221 1.3E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 219 2.1E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 SUPERFAMILY SSF52172 1 180 4.13E-45 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 Pfam PF00072 Response regulator receiver domain 6 114 8.9E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 SMART SM00862 148 219 6.7E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 SMART SM00448 4 114 2.0E-44 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_14435 e32f49b371c2e54aafc82d5ecaae517d 221 Gene3D G3DSA:3.40.50.2300 1 126 1.5E-41 T 01-11-2018 MLA2C4_13735 7be10d8f0d73ae1b68dffec258be769d 312 SUPERFAMILY SSF103481 47 141 1.83E-9 T 01-11-2018 MLA2C4_13735 7be10d8f0d73ae1b68dffec258be769d 312 SUPERFAMILY SSF103481 211 298 2.35E-14 T 01-11-2018 MLA2C4_13735 7be10d8f0d73ae1b68dffec258be769d 312 Pfam PF00892 EamA-like transporter family 152 294 7.7E-22 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_13735 7be10d8f0d73ae1b68dffec258be769d 312 Pfam PF00892 EamA-like transporter family 6 139 3.1E-21 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 SUPERFAMILY SSF46977 442 584 1.7E-45 T 01-11-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 SUPERFAMILY SSF51905 5 430 2.7E-65 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 5 578 2.2E-281 T 01-11-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 1.1E-6 T 01-11-2018 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.1E-6 T 01-11-2018 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 Pfam PF02910 Fumarate reductase flavoprotein C-term 451 578 5.0E-41 T 01-11-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 Gene3D G3DSA:3.90.700.10 257 366 7.3E-125 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 Gene3D G3DSA:3.50.50.60 6 402 7.3E-125 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 Gene3D G3DSA:1.20.58.100 422 538 6.6E-31 T 01-11-2018 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 38 47 - T 01-11-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 PIRSF PIRSF000171 1 239 8.1E-19 T 01-11-2018 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 PIRSF PIRSF000171 342 575 3.5E-13 T 01-11-2018 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 Pfam PF00890 FAD binding domain 5 391 6.5E-88 T 01-11-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 SUPERFAMILY SSF56425 230 352 3.14E-31 T 01-11-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.7E-9 T 01-11-2018 MLA2C4_23485 2d7f88ad53489fb1f3d8a803c0923979 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.7E-9 T 01-11-2018 MLA2C4_11005 1d75554bdc723d0b42933545f9058d87 503 SUPERFAMILY SSF55486 243 500 4.03E-40 T 01-11-2018 MLA2C4_11005 1d75554bdc723d0b42933545f9058d87 503 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 75 104 1.3E-6 T 01-11-2018 IPR011096 FTP domain MLA2C4_11005 1d75554bdc723d0b42933545f9058d87 503 Pfam PF02128 Fungalysin metallopeptidase (M36) 303 501 1.1E-13 T 01-11-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 MLA2C4_11005 1d75554bdc723d0b42933545f9058d87 503 Pfam PF03413 Peptidase propeptide and YPEB domain 122 192 1.9E-8 T 01-11-2018 IPR025711 PepSY domain MLA2C4_11005 1d75554bdc723d0b42933545f9058d87 503 Gene3D G3DSA:1.10.390.10 362 503 1.6E-9 T 01-11-2018 IPR027268 Peptidase M4/M1, CTD superfamily MLA2C4_02780 95bce14c979ec6816c9aedd5d4cad8d2 151 Pfam PF00578 AhpC/TSA family 4 131 1.2E-39 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_02780 95bce14c979ec6816c9aedd5d4cad8d2 151 PIRSF PIRSF000239 1 150 1.7E-28 T 01-11-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_02780 95bce14c979ec6816c9aedd5d4cad8d2 151 Gene3D G3DSA:3.40.30.10 2 151 3.2E-52 T 01-11-2018 MLA2C4_02780 95bce14c979ec6816c9aedd5d4cad8d2 151 SUPERFAMILY SSF52833 1 151 8.51E-54 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_04560 2c1c45c0fb05d394ac8c90f3b41bf478 114 SUPERFAMILY SSF103481 8 105 7.72E-13 T 01-11-2018 MLA2C4_04560 2c1c45c0fb05d394ac8c90f3b41bf478 114 Gene3D G3DSA:1.10.3730.20 3 108 4.2E-19 T 01-11-2018 MLA2C4_04560 2c1c45c0fb05d394ac8c90f3b41bf478 114 Pfam PF00893 Small Multidrug Resistance protein 5 93 1.1E-15 T 01-11-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MLA2C4_20225 ad213100113be6ef96f1db5d15e1a00c 70 SMART SM01409 8 61 4.7E-12 T 01-11-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MLA2C4_20225 ad213100113be6ef96f1db5d15e1a00c 70 Pfam PF01192 RNA polymerase Rpb6 9 60 1.4E-11 T 01-11-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MLA2C4_20225 ad213100113be6ef96f1db5d15e1a00c 70 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 3.7E-21 T 01-11-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_20225 ad213100113be6ef96f1db5d15e1a00c 70 SUPERFAMILY SSF63562 1 64 7.32E-19 T 01-11-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MLA2C4_20225 ad213100113be6ef96f1db5d15e1a00c 70 Gene3D G3DSA:3.90.940.10 1 68 1.0E-14 T 01-11-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MLA2C4_20225 ad213100113be6ef96f1db5d15e1a00c 70 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 12.74 T 01-11-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 Gene3D G3DSA:3.40.50.970 1 192 1.1E-80 T 01-11-2018 MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 SUPERFAMILY SSF52518 3 192 2.36E-66 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 SMART SM00861 4 179 1.9E-64 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 Gene3D G3DSA:3.40.50.920 193 325 4.7E-49 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 5.0E-40 T 01-11-2018 IPR033248 Transketolase, C-terminal domain MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 SUPERFAMILY SSF52922 188 325 3.01E-42 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_20755 9dc5b01ba9ea9414e329b8fbf117a9ec 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.3E-39 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_24225 17defd013e17a3b328cc8e7117faf695 572 SUPERFAMILY SSF56801 21 562 4.06E-162 T 01-11-2018 MLA2C4_24225 17defd013e17a3b328cc8e7117faf695 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_24225 17defd013e17a3b328cc8e7117faf695 572 Pfam PF00501 AMP-binding enzyme 55 462 1.6E-91 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_24225 17defd013e17a3b328cc8e7117faf695 572 Gene3D G3DSA:3.30.300.30 458 571 6.0E-28 T 01-11-2018 MLA2C4_24225 17defd013e17a3b328cc8e7117faf695 572 Gene3D G3DSA:3.40.50.12780 17 455 3.8E-122 T 01-11-2018 MLA2C4_24225 17defd013e17a3b328cc8e7117faf695 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 4.7E-24 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 SUPERFAMILY SSF103473 10 413 9.29E-39 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 Pfam PF07690 Major Facilitator Superfamily 25 377 8.1E-25 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 PRINTS PR01988 Putative bacilysin exporter bacE signature 151 172 4.4E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 PRINTS PR01988 Putative bacilysin exporter bacE signature 178 195 4.4E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 PRINTS PR01988 Putative bacilysin exporter bacE signature 59 77 4.4E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 PRINTS PR01988 Putative bacilysin exporter bacE signature 85 103 4.4E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 PRINTS PR01988 Putative bacilysin exporter bacE signature 370 393 4.4E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14185 bc33ddffb35de4792edf4b014037ee19 432 Gene3D G3DSA:1.20.1250.20 10 415 1.6E-34 T 01-11-2018 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 SUPERFAMILY SSF53850 89 291 1.19E-34 T 01-11-2018 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 Gene3D G3DSA:1.10.10.10 1 85 1.4E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 SUPERFAMILY SSF46785 1 86 1.8E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 Gene3D G3DSA:3.40.190.10 162 267 3.2E-65 T 01-11-2018 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.0E-22 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 Gene3D G3DSA:3.40.190.10 88 285 3.2E-65 T 01-11-2018 MLA2C4_19090 1d9218917dfc41e47a49be9931a9433f 301 Pfam PF03466 LysR substrate binding domain 87 291 1.6E-40 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_24570 ce681fe1ed3b1e84c72df1654f6adb47 161 Pfam PF01967 MoaC family 15 152 4.2E-53 T 01-11-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24570 ce681fe1ed3b1e84c72df1654f6adb47 161 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 9.1E-65 T 01-11-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24570 ce681fe1ed3b1e84c72df1654f6adb47 161 Gene3D G3DSA:3.30.70.640 1 161 1.2E-69 T 01-11-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24570 ce681fe1ed3b1e84c72df1654f6adb47 161 SUPERFAMILY SSF55040 11 157 1.31E-57 T 01-11-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24570 ce681fe1ed3b1e84c72df1654f6adb47 161 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.736 T 01-11-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_03195 dcd01afc7818a2f752c891ba98e585aa 337 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 100 247 2.0E-45 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_03195 dcd01afc7818a2f752c891ba98e585aa 337 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 100 248 5.0E-42 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_03195 dcd01afc7818a2f752c891ba98e585aa 337 Gene3D G3DSA:1.10.260.150 59 337 2.6E-87 T 01-11-2018 MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 SMART SM00448 2 112 2.0E-35 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 SMART SM00862 145 220 1.7E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 SUPERFAMILY SSF52172 1 168 6.79E-38 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 Gene3D G3DSA:3.40.50.2300 1 125 2.0E-33 T 01-11-2018 MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 Gene3D G3DSA:1.10.10.10 126 223 2.4E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 Pfam PF00072 Response regulator receiver domain 4 109 2.1E-26 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_17040 35c70f8a46a7c754da30e46ba77cdc83 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.6E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_01365 e1b491a6f465bc169b9ae3d0bcbb90e4 390 SUPERFAMILY SSF51182 5 382 4.82E-100 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_01365 e1b491a6f465bc169b9ae3d0bcbb90e4 390 Gene3D G3DSA:2.60.120.10 77 175 4.5E-8 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_01365 e1b491a6f465bc169b9ae3d0bcbb90e4 390 Gene3D G3DSA:2.60.120.10 267 360 1.5E-6 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_01365 e1b491a6f465bc169b9ae3d0bcbb90e4 390 Pfam PF04209 homogentisate 1,2-dioxygenase 98 382 5.3E-19 T 01-11-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 SUPERFAMILY SSF52540 103 322 4.56E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 Gene3D G3DSA:3.40.50.300 89 260 4.4E-47 T 01-11-2018 MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 Pfam PF03193 RsgA GTPase 86 261 5.3E-50 T 01-11-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 24 324 33.016 T 01-11-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 Gene3D G3DSA:1.10.40.50 263 333 1.6E-22 T 01-11-2018 MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 66 316 1.3E-50 T 01-11-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MLA2C4_10225 fe532983d40a49332ea3e49efc6909fc 349 SUPERFAMILY SSF50249 26 90 3.22E-8 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 SUPERFAMILY SSF55874 286 453 1.96E-43 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 SUPERFAMILY SSF47384 213 295 1.1E-16 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 454 1.6E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 SMART SM00304 174 229 9.6E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 Pfam PF00672 HAMP domain 177 225 5.6E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 295 1.9E-11 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 Gene3D G3DSA:3.30.565.10 302 457 1.1E-42 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 Gene3D G3DSA:1.10.287.130 178 298 6.4E-27 T 01-11-2018 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 SUPERFAMILY SSF158472 176 227 7.32E-5 T 01-11-2018 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 5.2E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 5.2E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 5.2E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 5.2E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 SMART SM00388 230 296 2.6E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_16920 747ccc7436bcfdb452650a8645049050 457 SMART SM00387 342 455 6.4E-34 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 SUPERFAMILY SSF56601 207 609 1.58E-96 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 Pfam PF00905 Penicillin binding protein transpeptidase domain 317 589 1.8E-35 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 Gene3D G3DSA:1.10.3810.10 61 249 3.8E-185 T 01-11-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 SUPERFAMILY SSF53955 40 244 1.43E-74 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 Pfam PF00912 Transglycosylase 51 225 1.3E-66 T 01-11-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 62 592 5.9E-172 T 01-11-2018 MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 Gene3D G3DSA:3.40.710.10 291 604 3.8E-185 T 01-11-2018 MLA2C4_05700 9d9ca34f96e00f06609f10dc8bed0d81 705 Gene3D G3DSA:3.90.1310.20 46 499 3.8E-185 T 01-11-2018 MLA2C4_04980 8c98dee87d28a0bb3b0d408634e54348 289 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 173 240 3.6E-18 T 01-11-2018 IPR006343 DnaD domain MLA2C4_04980 8c98dee87d28a0bb3b0d408634e54348 289 SUPERFAMILY SSF158499 172 233 2.35E-16 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_04980 8c98dee87d28a0bb3b0d408634e54348 289 Gene3D G3DSA:1.10.10.630 169 241 2.7E-19 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_04980 8c98dee87d28a0bb3b0d408634e54348 289 Pfam PF07261 Replication initiation and membrane attachment 173 241 2.4E-15 T 01-11-2018 IPR006343 DnaD domain MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 6.0E-26 T 01-11-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 SUPERFAMILY SSF55257 5 230 7.06E-33 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Gene3D G3DSA:3.30.1360.10 16 221 3.1E-91 T 01-11-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Gene3D G3DSA:2.170.120.12 50 170 3.1E-91 T 01-11-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.8 T 01-11-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 SMART SM00662 20 227 2.7E-108 T 01-11-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 4.0E-127 T 01-11-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 2.6E-25 T 01-11-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 SUPERFAMILY SSF47789 247 313 9.29E-25 T 01-11-2018 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Gene3D G3DSA:1.10.150.20 237 314 1.7E-34 T 01-11-2018 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 5.8E-24 T 01-11-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 SUPERFAMILY SSF56553 50 171 2.75E-45 T 01-11-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00810 fbbbec7f04c02bd99ca2745aba72d682 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 2.4E-29 T 01-11-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Pfam PF03793 PASTA domain 591 641 3.4E-7 T 01-11-2018 IPR005543 PASTA domain MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Pfam PF03793 PASTA domain 647 698 5.9E-6 T 01-11-2018 IPR005543 PASTA domain MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 SUPERFAMILY SSF56601 180 579 2.91E-89 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 207 1.5E-17 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 SMART SM00740 646 701 4.6 T 01-11-2018 IPR005543 PASTA domain MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 SMART SM00740 586 645 0.0092 T 01-11-2018 IPR005543 PASTA domain MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 SUPERFAMILY SSF54184 647 699 1.44E-11 T 01-11-2018 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Gene3D G3DSA:2.20.70.70 55 211 3.4E-37 T 01-11-2018 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Gene3D G3DSA:3.30.70.2110 77 151 3.4E-37 T 01-11-2018 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Gene3D G3DSA:3.40.710.10 222 574 1.9E-101 T 01-11-2018 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Pfam PF00905 Penicillin binding protein transpeptidase domain 257 565 1.8E-84 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 SUPERFAMILY SSF56519 56 228 9.16E-37 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 SUPERFAMILY SSF54184 587 642 3.27E-11 T 01-11-2018 MLA2C4_14140 739e13948c364dbf7cae26885986dcd8 712 Gene3D G3DSA:3.90.1310.10 58 195 3.4E-37 T 01-11-2018 MLA2C4_18020 70b686b18e683b3c5c95d965ffcba30c 116 Pfam PF08830 Protein of unknown function (DUF1806) 8 115 1.3E-54 T 01-11-2018 IPR014934 Protein of unknown function DUF1806 MLA2C4_18020 70b686b18e683b3c5c95d965ffcba30c 116 Gene3D G3DSA:2.70.180.10 2 116 9.2E-51 T 01-11-2018 IPR036492 Hypothetical protein YojF superfamily MLA2C4_18020 70b686b18e683b3c5c95d965ffcba30c 116 SUPERFAMILY SSF89442 8 116 4.97E-54 T 01-11-2018 IPR036492 Hypothetical protein YojF superfamily MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 SMART SM00857 11 160 2.5E-56 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 Pfam PF07508 Recombinase 181 278 3.7E-28 T 01-11-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 Pfam PF13408 Recombinase zinc beta ribbon domain 295 352 5.2E-13 T 01-11-2018 IPR025827 Recombinase zinc beta ribbon domain MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 ProSitePatterns PS00397 Site-specific recombinases active site. 14 22 - T 01-11-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 Gene3D G3DSA:1.10.10.2600 144 283 3.5E-22 T 01-11-2018 IPR038109 DNA-binding recombinase domain superfamily MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 Gene3D G3DSA:3.40.50.1390 8 142 6.5E-43 T 01-11-2018 MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 Pfam PF00239 Resolvase, N terminal domain 12 160 8.9E-41 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_04165 dd517762c8377a229e31e9b20a49eea0 483 SUPERFAMILY SSF53041 10 160 1.57E-37 T 01-11-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 6 443 2.3E-149 T 01-11-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 321 333 2.9E-31 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 2.9E-31 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 2.9E-31 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 387 2.9E-31 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 425 442 2.9E-31 T 01-11-2018 IPR023267 RNA (C5-cytosine) methyltransferase MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 441 5.7E-61 T 01-11-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 SUPERFAMILY SSF53335 136 443 3.35E-77 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 320 331 - T 01-11-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 SUPERFAMILY SSF48013 2 127 3.27E-39 T 01-11-2018 IPR035926 NusB-like superfamily MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 Gene3D G3DSA:3.40.50.150 142 442 2.2E-86 T 01-11-2018 MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 Pfam PF01029 NusB family 4 125 4.3E-32 T 01-11-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MLA2C4_20200 c9555723a459fbaa4483b50333de5c30 444 Gene3D G3DSA:1.10.940.10 1 140 6.9E-40 T 01-11-2018 IPR035926 NusB-like superfamily MLA2C4_02255 5d84ab2bce375ac22c7c887ee787843b 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_02255 5d84ab2bce375ac22c7c887ee787843b 299 Gene3D G3DSA:3.40.50.300 1 232 2.5E-62 T 01-11-2018 MLA2C4_02255 5d84ab2bce375ac22c7c887ee787843b 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 2.8E-18 T 01-11-2018 IPR025302 Domain of unknown function DUF4162 MLA2C4_02255 5d84ab2bce375ac22c7c887ee787843b 299 Pfam PF00005 ABC transporter 19 158 3.7E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_02255 5d84ab2bce375ac22c7c887ee787843b 299 SUPERFAMILY SSF52540 3 223 7.99E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02255 5d84ab2bce375ac22c7c887ee787843b 299 SMART SM00382 27 231 1.2E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 Pfam PF02421 Ferrous iron transport protein B 3 153 5.8E-59 T 01-11-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 SUPERFAMILY SSF52540 3 162 9.31E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 Gene3D G3DSA:3.40.50.300 1 167 7.9E-41 T 01-11-2018 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 628 3.9E-195 T 01-11-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 Pfam PF07664 Ferrous iron transport protein B C terminus 451 503 1.8E-18 T 01-11-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 Pfam PF07670 Nucleoside recognition 347 440 2.2E-15 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 Pfam PF07670 Nucleoside recognition 508 631 1.3E-33 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 50 65 5.5E-5 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_25030 346d237725444d5bc8fe4dd9aff587cc 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 5.5E-5 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_24560 2fbc23e9171a19a2c5de79e18b7cf9f4 171 SUPERFAMILY SSF52540 6 137 2.92E-18 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_24560 2fbc23e9171a19a2c5de79e18b7cf9f4 171 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 7 157 2.7E-32 T 01-11-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 MLA2C4_24560 2fbc23e9171a19a2c5de79e18b7cf9f4 171 Gene3D G3DSA:3.40.50.300 3 171 8.9E-53 T 01-11-2018 MLA2C4_24560 2fbc23e9171a19a2c5de79e18b7cf9f4 171 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 7 137 8.7E-35 T 01-11-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Pfam PF17170 6-bladed beta-propeller 180 254 3.3E-8 T 01-11-2018 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 SUPERFAMILY SSF101898 261 550 2.88E-38 T 01-11-2018 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Pfam PF01436 NHL repeat 74 101 1.2E-6 T 01-11-2018 IPR001258 NHL repeat GO:0005515 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Pfam PF01436 NHL repeat 121 148 3.6E-7 T 01-11-2018 IPR001258 NHL repeat GO:0005515 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Pfam PF01436 NHL repeat 414 441 2.2E-10 T 01-11-2018 IPR001258 NHL repeat GO:0005515 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 SUPERFAMILY SSF101898 27 289 2.3E-49 T 01-11-2018 MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Gene3D G3DSA:2.120.10.30 513 598 3.2E-19 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Gene3D G3DSA:2.120.10.30 65 157 7.4E-38 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Gene3D G3DSA:2.120.10.30 4 64 4.4E-7 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Gene3D G3DSA:2.120.10.30 358 443 1.8E-25 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Gene3D G3DSA:2.120.10.30 158 350 3.5E-48 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_09805 f46b3ed71086a1c40e7ce1822da08dde 598 Gene3D G3DSA:2.40.10.500 454 512 4.7E-9 T 01-11-2018 MLA2C4_25700 fcc2607e2d75ba2bea220700eb1e423c 117 Gene3D G3DSA:2.60.300.12 1 109 7.8E-34 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MLA2C4_25700 fcc2607e2d75ba2bea220700eb1e423c 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 1.4E-34 T 01-11-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MLA2C4_25700 fcc2607e2d75ba2bea220700eb1e423c 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 01-11-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MLA2C4_25700 fcc2607e2d75ba2bea220700eb1e423c 117 SUPERFAMILY SSF89360 1 95 8.04E-26 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MLA2C4_25700 fcc2607e2d75ba2bea220700eb1e423c 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 5.6E-19 T 01-11-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MLA2C4_25755 2a338c2b1e32fe6ecdd2bcb08d1628b3 102 SUPERFAMILY SSF52833 2 101 1.36E-40 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_25755 2a338c2b1e32fe6ecdd2bcb08d1628b3 102 Gene3D G3DSA:3.40.30.30 1 102 1.3E-38 T 01-11-2018 IPR038218 YuzD-like superfamily MLA2C4_25755 2a338c2b1e32fe6ecdd2bcb08d1628b3 102 Pfam PF07315 Protein of unknown function (DUF1462) 6 99 2.5E-41 T 01-11-2018 IPR009190 Protein of unknown function DUF1462 MLA2C4_25755 2a338c2b1e32fe6ecdd2bcb08d1628b3 102 PIRSF PIRSF010603 1 102 6.8E-48 T 01-11-2018 IPR009190 Protein of unknown function DUF1462 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Pfam PF00128 Alpha amylase, catalytic domain 258 342 2.1E-6 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Pfam PF00128 Alpha amylase, catalytic domain 376 575 1.4E-7 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Gene3D G3DSA:2.60.40.1180 623 712 4.2E-25 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 SMART SM00642 238 613 5.6E-7 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Gene3D G3DSA:2.60.40.2320 1 95 9.5E-34 T 01-11-2018 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 105 181 9.1E-15 T 01-11-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 SUPERFAMILY SSF51445 199 620 3.28E-119 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Gene3D G3DSA:3.20.20.80 202 622 2.1E-171 T 01-11-2018 MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 SUPERFAMILY SSF81296 98 200 6.4E-22 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 94 690 2.9E-267 T 01-11-2018 IPR011840 Pullulanase, type I MLA2C4_24455 150f791cc35cb20ae2bcadede35608c9 713 Gene3D G3DSA:2.60.40.10 96 201 3.8E-29 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 Pfam PF13646 HEAT repeats 267 351 2.7E-12 T 01-11-2018 MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 SMART SM00567 E-Z type HEAT repeats 279 308 17.0 T 01-11-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 SMART SM00567 E-Z type HEAT repeats 248 277 5.8 T 01-11-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 SMART SM00567 E-Z type HEAT repeats 310 339 3.4E-5 T 01-11-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 Pfam PF13769 Virulence factor 107 185 2.2E-28 T 01-11-2018 IPR025989 Virulence factor domain MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 SUPERFAMILY SSF48371 207 372 1.2E-30 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 Gene3D G3DSA:3.30.1370.70 1 92 1.5E-27 T 01-11-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 SUPERFAMILY SSF110836 3 88 7.98E-23 T 01-11-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 Gene3D G3DSA:1.25.10.10 192 374 8.3E-26 T 01-11-2018 IPR011989 Armadillo-like helical MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 86 8.7E-19 T 01-11-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal MLA2C4_10965 7ea8b2bb80b55f5e76db2bd7e5e0983b 375 SMART SM00932 4 90 3.8E-27 T 01-11-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal MLA2C4_11775 995357d8d700a9218e25cb3118a15e76 429 Gene3D G3DSA:3.40.50.300 5 232 6.8E-60 T 01-11-2018 MLA2C4_11775 995357d8d700a9218e25cb3118a15e76 429 Pfam PF04466 Phage terminase large subunit 19 230 5.4E-73 T 01-11-2018 IPR035412 Phage terminase large subunit, N-terminal MLA2C4_11775 995357d8d700a9218e25cb3118a15e76 429 Gene3D G3DSA:3.30.420.280 241 415 2.2E-34 T 01-11-2018 MLA2C4_11775 995357d8d700a9218e25cb3118a15e76 429 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 19 421 5.2E-89 T 01-11-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 MLA2C4_11775 995357d8d700a9218e25cb3118a15e76 429 Pfam PF17288 Terminase RNAseH like domain 268 409 4.8E-36 T 01-11-2018 IPR035413 Phage terminase large subunit, C-terminal MLA2C4_01825 b4cdd6ec1b06677ff0b74aea038f3315 229 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 8.2E-76 T 01-11-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 MLA2C4_01825 b4cdd6ec1b06677ff0b74aea038f3315 229 Pfam PF01884 PcrB family 2 226 4.9E-87 T 01-11-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 MLA2C4_01825 b4cdd6ec1b06677ff0b74aea038f3315 229 SUPERFAMILY SSF51395 6 223 6.59E-55 T 01-11-2018 MLA2C4_01825 b4cdd6ec1b06677ff0b74aea038f3315 229 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.021 T 01-11-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 MLA2C4_01825 b4cdd6ec1b06677ff0b74aea038f3315 229 Gene3D G3DSA:3.20.20.390 1 229 1.6E-98 T 01-11-2018 IPR038597 GGGP/HepGP synthase superfamily MLA2C4_10085 0b585bee867d7f4d5bf3cc22bbe1c22a 412 SUPERFAMILY SSF56801 97 405 4.06E-58 T 01-11-2018 MLA2C4_10085 0b585bee867d7f4d5bf3cc22bbe1c22a 412 ProSitePatterns PS00455 Putative AMP-binding domain signature. 107 118 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_10085 0b585bee867d7f4d5bf3cc22bbe1c22a 412 Gene3D G3DSA:3.30.300.30 313 409 1.6E-19 T 01-11-2018 MLA2C4_10085 0b585bee867d7f4d5bf3cc22bbe1c22a 412 Pfam PF00501 AMP-binding enzyme 56 279 2.8E-22 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_10085 0b585bee867d7f4d5bf3cc22bbe1c22a 412 Pfam PF13193 AMP-binding enzyme C-terminal domain 328 399 1.4E-11 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_10085 0b585bee867d7f4d5bf3cc22bbe1c22a 412 Gene3D G3DSA:3.40.50.12780 1 308 3.5E-29 T 01-11-2018 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 6.7E-32 T 01-11-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 SUPERFAMILY SSF54368 5 104 1.03E-34 T 01-11-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 01-11-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 SMART SM01230 105 354 5.2E-141 T 01-11-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 01-11-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 SUPERFAMILY SSF55931 105 442 2.65E-130 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.7E-140 T 01-11-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 3.2E-185 T 01-11-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 Gene3D G3DSA:3.10.20.70 2 107 1.6E-44 T 01-11-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 01-11-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MLA2C4_19350 61f36c15ad9428b93efba91b39622be7 444 Gene3D G3DSA:3.30.590.10 108 444 5.8E-147 T 01-11-2018 MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 01-11-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 SUPERFAMILY SSF54211 4 85 4.55E-29 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 40.273 T 01-11-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 Gene3D G3DSA:3.30.230.40 90 194 6.6E-37 T 01-11-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 8.5E-65 T 01-11-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 SUPERFAMILY SSF54211 87 178 4.86E-35 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 01-11-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MLA2C4_07440 0349f1637b01175c08b3fb5c8a9fe405 194 Gene3D G3DSA:3.30.230.40 1 89 4.2E-33 T 01-11-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MLA2C4_02415 440c2117c04dbd3b2dffe6186f9d7630 192 Pfam PF02342 TerD domain 1 188 2.6E-84 T 01-11-2018 IPR003325 TerD domain MLA2C4_02415 440c2117c04dbd3b2dffe6186f9d7630 192 Gene3D G3DSA:2.60.60.30 19 187 3.7E-72 T 01-11-2018 MLA2C4_20510 9388c090445619cf4fe80c7628e84a6b 408 Hamap MF_01539 UPF0348 protein . 1 399 39.314 T 01-11-2018 IPR008513 Uncharacterised protein family UPF0348 MLA2C4_20510 9388c090445619cf4fe80c7628e84a6b 408 Gene3D G3DSA:3.40.50.620 1 239 7.1E-39 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_20510 9388c090445619cf4fe80c7628e84a6b 408 Pfam PF05636 HIGH Nucleotidyl Transferase 1 382 1.2E-135 T 01-11-2018 IPR008513 Uncharacterised protein family UPF0348 MLA2C4_20510 9388c090445619cf4fe80c7628e84a6b 408 SUPERFAMILY SSF52374 5 233 2.43E-16 T 01-11-2018 MLA2C4_18725 13b193563c0812e62d835bd1b6dcaced 139 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 9.6E-30 T 01-11-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MLA2C4_18725 13b193563c0812e62d835bd1b6dcaced 139 Gene3D G3DSA:3.10.129.10 4 136 3.2E-33 T 01-11-2018 MLA2C4_18725 13b193563c0812e62d835bd1b6dcaced 139 Pfam PF03061 Thioesterase superfamily 18 102 7.6E-14 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_18725 13b193563c0812e62d835bd1b6dcaced 139 SUPERFAMILY SSF54637 2 133 3.09E-36 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_18725 13b193563c0812e62d835bd1b6dcaced 139 PIRSF PIRSF003230 1 135 6.8E-30 T 01-11-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 SUPERFAMILY SSF75625 1 238 1.83E-80 T 01-11-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.977 T 01-11-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 Gene3D G3DSA:1.10.10.200 2 79 3.7E-24 T 01-11-2018 IPR017856 Integrase-like, N-terminal MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 Pfam PF01709 Transcriptional regulator 4 235 3.9E-81 T 01-11-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.317 T 01-11-2018 IPR026562 Probable transcriptional regulatory protein YeeN MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 Gene3D G3DSA:3.30.70.980 127 203 4.7E-45 T 01-11-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 Gene3D G3DSA:3.30.70.980 83 234 4.7E-45 T 01-11-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_02890 277a1a4dd770cea253e990738698b6b8 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 1.5E-71 T 01-11-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03450 f9dd212eda740b56a68f971288ca6beb 483 Pfam PF00916 Sulfate permease family 14 139 7.2E-25 T 01-11-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MLA2C4_03450 f9dd212eda740b56a68f971288ca6beb 483 Pfam PF00916 Sulfate permease family 144 354 3.1E-32 T 01-11-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MLA2C4_03450 f9dd212eda740b56a68f971288ca6beb 483 Gene3D G3DSA:3.30.750.24 382 478 1.2E-26 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_03450 f9dd212eda740b56a68f971288ca6beb 483 SUPERFAMILY SSF52091 387 472 1.29E-9 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_23750 af07b4cd57164bbf2adc17830837a921 361 SUPERFAMILY SSF53187 8 355 1.89E-71 T 01-11-2018 MLA2C4_23750 af07b4cd57164bbf2adc17830837a921 361 Gene3D G3DSA:3.40.630.10 12 345 5.1E-136 T 01-11-2018 MLA2C4_23750 af07b4cd57164bbf2adc17830837a921 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 7.2E-118 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_23750 af07b4cd57164bbf2adc17830837a921 361 PIRSF PIRSF001123 4 361 1.5E-150 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_23750 af07b4cd57164bbf2adc17830837a921 361 SUPERFAMILY SSF101821 73 182 2.14E-34 T 01-11-2018 MLA2C4_23750 af07b4cd57164bbf2adc17830837a921 361 Gene3D G3DSA:2.40.30.40 77 164 5.1E-136 T 01-11-2018 IPR023367 Peptidase M42, domain 2 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 4.1E-39 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 4.1E-39 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 4.1E-39 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 4.1E-39 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 4.1E-39 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 151 4.9E-48 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 8.0E-81 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 32.877 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 Gene3D G3DSA:3.30.1360.80 1 157 6.6E-59 T 01-11-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 SUPERFAMILY SSF63411 4 152 1.74E-58 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_24950 fe6d3d15bc78938f5e83751d3104569f 157 PIRSF PIRSF006160 1 157 7.8E-59 T 01-11-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_17360 c599cfad06af6e19e143d8e953e260d4 152 Pfam PF10020 Uncharacterized protein conserved in bacteria (DUF2262) 9 152 9.9E-19 T 01-11-2018 IPR019260 Domain of unknown function DUF2262 MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 SMART SM00382 385 571 9.0E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 SUPERFAMILY SSF52540 349 596 2.72E-91 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 Pfam PF00005 ABC transporter 376 525 2.9E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 SUPERFAMILY SSF90123 31 343 1.57E-82 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 Pfam PF00664 ABC transporter transmembrane region 43 314 2.3E-55 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 Gene3D G3DSA:1.20.1560.10 10 346 1.7E-102 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 Gene3D G3DSA:3.40.50.300 356 598 4.9E-88 T 01-11-2018 MLA2C4_12525 37cd55f41c310571ece2f36c0e7fb4a2 598 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_24415 e80de77aafbf27fedd356fcfb6d2d555 104 SUPERFAMILY SSF52833 4 102 1.37E-26 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_24415 e80de77aafbf27fedd356fcfb6d2d555 104 Gene3D G3DSA:3.40.30.10 1 102 1.2E-23 T 01-11-2018 MLA2C4_24415 e80de77aafbf27fedd356fcfb6d2d555 104 Pfam PF00085 Thioredoxin 11 101 6.0E-17 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 MLA2C4_00015 f554f2aa3dc3c2baef92ddc78c0add9c 70 Pfam PF13275 S4 domain 4 68 2.8E-27 T 01-11-2018 MLA2C4_00015 f554f2aa3dc3c2baef92ddc78c0add9c 70 SUPERFAMILY SSF55174 2 65 3.87E-18 T 01-11-2018 MLA2C4_00015 f554f2aa3dc3c2baef92ddc78c0add9c 70 Gene3D G3DSA:3.10.290.10 1 68 6.1E-24 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_00015 f554f2aa3dc3c2baef92ddc78c0add9c 70 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 62 5.4E-32 T 01-11-2018 IPR014330 RNA-binding S4-related,YaaA MLA2C4_17190 db03c9f0e8c7d2990a3ff2cb849add12 414 Gene3D G3DSA:1.20.1250.20 21 405 2.1E-41 T 01-11-2018 MLA2C4_17190 db03c9f0e8c7d2990a3ff2cb849add12 414 SUPERFAMILY SSF103473 14 410 6.93E-53 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_17190 db03c9f0e8c7d2990a3ff2cb849add12 414 Pfam PF07690 Major Facilitator Superfamily 33 209 2.4E-24 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_17190 db03c9f0e8c7d2990a3ff2cb849add12 414 Pfam PF07690 Major Facilitator Superfamily 236 409 1.1E-12 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 Pfam PF08264 Anticodon-binding domain of tRNA 675 817 2.0E-30 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1026 13.898 T 01-11-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 Gene3D G3DSA:1.10.730.10 631 811 5.9E-50 T 01-11-2018 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 Gene3D G3DSA:3.40.50.620 14 615 1.7E-251 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_11000 8526cce333887880f73732207ae86936 1033 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 623 1.3E-191 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 SUPERFAMILY SSF52374 12 637 4.22E-137 T 01-11-2018 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 830 1.0E-289 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 SUPERFAMILY SSF47323 946 1014 2.35E-5 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 SUPERFAMILY SSF47323 645 878 6.17E-50 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 5.0E-30 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 382 397 5.0E-30 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 5.0E-30 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 5.0E-30 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 5.0E-30 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 Gene3D G3DSA:3.90.740.10 196 388 1.7E-251 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_11000 8526cce333887880f73732207ae86936 1033 SUPERFAMILY SSF50677 200 384 4.6E-51 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 Pfam PF00842 Alanine racemase, C-terminal domain 248 375 2.5E-47 T 01-11-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 Gene3D G3DSA:2.40.37.10 11 375 4.5E-133 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 33 49 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 358 371 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 207 234 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 281 296 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 302 319 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 69 87 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 264 279 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 130 142 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 PRINTS PR00992 Alanine racemase signature 164 175 2.0E-61 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 SUPERFAMILY SSF50621 243 382 1.46E-52 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 SMART SM01005 248 376 6.8E-71 T 01-11-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 SUPERFAMILY SSF51419 13 249 8.6E-66 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 Pfam PF01168 Alanine racemase, N-terminal domain 13 234 2.1E-66 T 01-11-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 01-11-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 Gene3D G3DSA:3.20.20.10 15 230 4.5E-133 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 Hamap MF_01201 Alanine racemase. 6 376 34.527 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_10565 cbc3996b6b9e5bbac08614c851201f20 391 TIGRFAM TIGR00492 alr: alanine racemase 7 375 1.6E-119 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_15260 4bd7a2b0211a6cc0c83a606163238758 578 SUPERFAMILY SSF53850 132 576 1.41E-65 T 01-11-2018 MLA2C4_15260 4bd7a2b0211a6cc0c83a606163238758 578 Gene3D G3DSA:3.10.105.10 357 547 8.0E-11 T 01-11-2018 MLA2C4_15260 4bd7a2b0211a6cc0c83a606163238758 578 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 179 498 3.1E-30 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_15260 4bd7a2b0211a6cc0c83a606163238758 578 Gene3D G3DSA:3.40.190.10 136 356 6.5E-35 T 01-11-2018 MLA2C4_15260 4bd7a2b0211a6cc0c83a606163238758 578 Pfam PF12793 Sugar transport-related sRNA regulator N-term 4 107 4.4E-23 T 01-11-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain MLA2C4_15260 4bd7a2b0211a6cc0c83a606163238758 578 PIRSF PIRSF002741 123 577 6.3E-36 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_05830 5745d1fdb6e105ee383cc18957fc1530 305 Pfam PF12146 Serine aminopeptidase, S33 32 187 6.5E-9 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_05830 5745d1fdb6e105ee383cc18957fc1530 305 Gene3D G3DSA:3.40.50.1820 12 287 3.3E-88 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05830 5745d1fdb6e105ee383cc18957fc1530 305 SUPERFAMILY SSF53474 3 305 4.55E-41 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05830 5745d1fdb6e105ee383cc18957fc1530 305 Gene3D G3DSA:1.10.10.800 143 228 3.3E-88 T 01-11-2018 MLA2C4_07620 8491c19087e8620cf45ec8f6ee06ae4c 258 Pfam PF08241 Methyltransferase domain 40 134 1.1E-27 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_07620 8491c19087e8620cf45ec8f6ee06ae4c 258 Gene3D G3DSA:3.40.50.150 2 257 2.0E-40 T 01-11-2018 MLA2C4_07620 8491c19087e8620cf45ec8f6ee06ae4c 258 SUPERFAMILY SSF53335 17 196 2.3E-38 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 Pfam PF01047 MarR family 36 94 2.8E-15 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 SUPERFAMILY SSF46785 7 139 2.38E-34 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 Gene3D G3DSA:1.10.10.10 2 144 1.7E-37 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.2E-5 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.2E-5 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.2E-5 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_23285 2128fc142ab2ad62b516a76a05b34234 150 SMART SM00347 29 127 3.1E-20 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_24600 b08046536e9c896890fe2b78f8b4954e 101 Gene3D G3DSA:3.40.250.10 4 100 1.1E-26 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_24600 b08046536e9c896890fe2b78f8b4954e 101 SMART SM00450 7 101 6.1E-11 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_24600 b08046536e9c896890fe2b78f8b4954e 101 Pfam PF00581 Rhodanese-like domain 8 97 1.6E-11 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_24600 b08046536e9c896890fe2b78f8b4954e 101 SUPERFAMILY SSF52821 3 97 4.45E-26 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04920 72f0f1d513aa8721154ee3fc279c8bee 225 SUPERFAMILY SSF52172 1 140 1.2E-27 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_04920 72f0f1d513aa8721154ee3fc279c8bee 225 Gene3D G3DSA:3.40.50.12740 2 207 4.1E-28 T 01-11-2018 MLA2C4_04920 72f0f1d513aa8721154ee3fc279c8bee 225 SMART SM00448 2 115 3.3E-18 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_04920 72f0f1d513aa8721154ee3fc279c8bee 225 Pfam PF00072 Response regulator receiver domain 4 115 1.6E-19 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_04920 72f0f1d513aa8721154ee3fc279c8bee 225 PIRSF PIRSF006171 1 224 1.4E-78 T 01-11-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 MLA2C4_24880 584b636c77af2a88d3a02604695926ae 254 SUPERFAMILY SSF52540 4 216 3.1E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_24880 584b636c77af2a88d3a02604695926ae 254 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_24880 584b636c77af2a88d3a02604695926ae 254 SMART SM00382 32 211 3.4E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_24880 584b636c77af2a88d3a02604695926ae 254 Gene3D G3DSA:3.40.50.300 3 235 3.6E-64 T 01-11-2018 MLA2C4_24880 584b636c77af2a88d3a02604695926ae 254 Pfam PF00005 ABC transporter 23 162 4.2E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 SUPERFAMILY SSF53800 2 305 1.08E-88 T 01-11-2018 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 Hamap MF_00323 Ferrochelatase [hemH]. 3 307 30.636 T 01-11-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 ProSitePatterns PS00534 Ferrochelatase signature. 177 195 - T 01-11-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 Gene3D G3DSA:3.40.50.1400 147 288 3.3E-110 T 01-11-2018 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 Pfam PF00762 Ferrochelatase 4 306 2.7E-82 T 01-11-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 TIGRFAM TIGR00109 hemH: ferrochelatase 2 307 7.1E-96 T 01-11-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_05710 49d721825be1ee59c8b8d058a7041ee1 311 Gene3D G3DSA:3.40.50.1400 7 303 3.3E-110 T 01-11-2018 MLA2C4_11395 e74c7e0ffd3bff2d6b48e140890d5203 185 Gene3D G3DSA:3.40.50.620 58 165 3.3E-6 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_11395 e74c7e0ffd3bff2d6b48e140890d5203 185 Pfam PF02698 DUF218 domain 38 175 9.3E-29 T 01-11-2018 IPR003848 Domain of unknown function DUF218 MLA2C4_26160 50ce06294502aa3640473b0c40e7a014 128 Pfam PF13074 Protein of unknown function (DUF3938) 25 126 1.7E-69 T 01-11-2018 IPR025070 Protein of unknown function DUF3938 MLA2C4_19170 f711f308a0db2f04fc328d7aeda5efcd 267 Gene3D G3DSA:1.10.3720.10 70 266 3.9E-37 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_19170 f711f308a0db2f04fc328d7aeda5efcd 267 SUPERFAMILY SSF161098 71 258 2.49E-38 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_19170 f711f308a0db2f04fc328d7aeda5efcd 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 263 2.2E-17 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_19170 f711f308a0db2f04fc328d7aeda5efcd 267 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 14 266 2.2E-90 T 01-11-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 363 3.2E-39 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Gene3D G3DSA:1.10.601.10 137 214 5.0E-51 T 01-11-2018 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Gene3D G3DSA:1.10.601.10 102 136 4.5E-11 T 01-11-2018 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Pfam PF04542 Sigma-70 region 2 142 211 3.7E-22 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Gene3D G3DSA:1.10.10.10 215 290 8.1E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 166 179 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Pfam PF04545 Sigma-70, region 4 310 363 5.2E-20 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Pfam PF03979 Sigma-70 factor, region 1.1 17 81 5.3E-16 T 01-11-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 138 374 1.1E-124 T 01-11-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Pfam PF00140 Sigma-70 factor, region 1.2 104 137 9.2E-18 T 01-11-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Pfam PF04539 Sigma-70 region 3 221 297 1.4E-31 T 01-11-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 SUPERFAMILY SSF88659 215 288 2.43E-22 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Gene3D G3DSA:1.10.220.120 15 75 3.2E-9 T 01-11-2018 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 PRINTS PR00046 Major sigma-70 factor signature 314 326 3.2E-32 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 PRINTS PR00046 Major sigma-70 factor signature 190 198 3.2E-32 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 PRINTS PR00046 Major sigma-70 factor signature 335 350 3.2E-32 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 PRINTS PR00046 Major sigma-70 factor signature 166 179 3.2E-32 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 PRINTS PR00046 Major sigma-70 factor signature 350 361 3.2E-32 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 11 375 34.002 T 01-11-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 Gene3D G3DSA:1.10.10.10 291 375 2.2E-36 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 SUPERFAMILY SSF88659 272 373 4.11E-30 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 335 361 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22430 b194e318c0423bdda54b628ad79f8e0f 375 SUPERFAMILY SSF88946 103 212 1.96E-54 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22550 eab22f3228eddce8fb2005e41dca74e8 124 SUPERFAMILY SSF46785 16 119 1.52E-33 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22550 eab22f3228eddce8fb2005e41dca74e8 124 Pfam PF01638 HxlR-like helix-turn-helix 28 117 2.0E-33 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_22550 eab22f3228eddce8fb2005e41dca74e8 124 Gene3D G3DSA:1.10.10.10 3 124 5.7E-39 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10550 d1852bd2b4bfa3f1ea2bd03c809d1428 196 SMART SM00855 2 150 2.3E-20 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_10550 d1852bd2b4bfa3f1ea2bd03c809d1428 196 SUPERFAMILY SSF53254 2 194 1.2E-47 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_10550 d1852bd2b4bfa3f1ea2bd03c809d1428 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 190 3.9E-45 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_10550 d1852bd2b4bfa3f1ea2bd03c809d1428 196 Gene3D G3DSA:3.40.50.1240 1 196 6.1E-48 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_10550 d1852bd2b4bfa3f1ea2bd03c809d1428 196 PIRSF PIRSF000709 1 176 5.6E-14 T 01-11-2018 MLA2C4_19900 28a7893e97f8713fbce210ae9a1792fd 299 SUPERFAMILY SSF88713 86 294 6.45E-64 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_19900 28a7893e97f8713fbce210ae9a1792fd 299 Gene3D G3DSA:3.20.20.370 60 297 1.7E-62 T 01-11-2018 MLA2C4_19900 28a7893e97f8713fbce210ae9a1792fd 299 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 27 294 5.9E-154 T 01-11-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY MLA2C4_19900 28a7893e97f8713fbce210ae9a1792fd 299 Pfam PF01522 Polysaccharide deacetylase 106 224 7.8E-31 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_22425 802d528e01f11cd3c5e833b7c1b6e870 118 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 47 114 1.7E-11 T 01-11-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_22425 802d528e01f11cd3c5e833b7c1b6e870 118 SUPERFAMILY SSF46626 5 116 3.99E-16 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_22425 802d528e01f11cd3c5e833b7c1b6e870 118 Gene3D G3DSA:1.10.760.10 49 118 1.0E-27 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_22425 802d528e01f11cd3c5e833b7c1b6e870 118 PIRSF PIRSF000025 1 118 1.6E-41 T 01-11-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 361 4.0E-133 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 PIRSF PIRSF001434 1 365 3.1E-122 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 Gene3D G3DSA:3.40.640.10 3 245 2.3E-87 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 Gene3D G3DSA:3.90.1150.10 279 369 6.8E-26 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 SUPERFAMILY SSF53383 17 361 6.52E-102 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22250 c33f3938f783d45480463c1275370e5b 370 Gene3D G3DSA:3.90.1150.10 246 278 5.1E-6 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 SUPERFAMILY SSF50249 50 114 3.31E-7 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Gene3D G3DSA:1.10.720.10 1 47 1.4E-20 T 01-11-2018 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 SMART SM00382 168 353 1.2E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 SMART SM00357 54 119 1.2E-19 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 223.235 T 01-11-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 SUPERFAMILY SSF52540 91 369 3.32E-65 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 SMART SM00959 7 49 1.0E-15 T 01-11-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Pfam PF07498 Rho termination factor, N-terminal domain 8 49 1.4E-15 T 01-11-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 SUPERFAMILY SSF68912 4 49 5.89E-11 T 01-11-2018 IPR036269 Rho termination factor, N-terminal domain superfamily MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Gene3D G3DSA:2.40.50.140 48 124 1.0E-29 T 01-11-2018 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 TIGRFAM TIGR00767 rho: transcription termination factor Rho 4 412 1.2E-204 T 01-11-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 361 2.5E-18 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Pfam PF07497 Rho termination factor, RNA-binding domain 53 126 1.6E-31 T 01-11-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MLA2C4_27610 82ce8a6527cae82fa6ff43e578cefb98 423 Gene3D G3DSA:3.40.50.300 131 413 2.0E-122 T 01-11-2018 MLA2C4_03765 29491bc36dd30de780397beb9003823b 296 SUPERFAMILY SSF161098 29 287 5.23E-36 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03765 29491bc36dd30de780397beb9003823b 296 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 14 293 5.5E-85 T 01-11-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MLA2C4_03765 29491bc36dd30de780397beb9003823b 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 293 8.1E-25 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03765 29491bc36dd30de780397beb9003823b 296 Gene3D G3DSA:1.10.3720.10 70 295 7.6E-34 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_04510 d83913712dd1158d68624713092d62d8 454 SUPERFAMILY SSF55604 7 82 4.45E-19 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_04510 d83913712dd1158d68624713092d62d8 454 Pfam PF02378 Phosphotransferase system, EIIC 121 389 1.5E-34 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_04510 d83913712dd1158d68624713092d62d8 454 Gene3D G3DSA:3.30.1360.60 1 78 2.3E-22 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_04510 d83913712dd1158d68624713092d62d8 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_04510 d83913712dd1158d68624713092d62d8 454 Pfam PF00367 phosphotransferase system, EIIB 9 42 5.9E-14 T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 Gene3D G3DSA:1.10.10.10 123 223 2.8E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03110 57f355580ade3279af12721d58707d34 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 3.9E-22 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 Pfam PF00072 Response regulator receiver domain 4 113 4.8E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 Gene3D G3DSA:3.40.50.2300 2 122 2.4E-39 T 01-11-2018 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 SMART SM00448 2 112 1.5E-41 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 SUPERFAMILY SSF46894 120 221 6.8E-26 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 SMART SM00862 143 220 3.5E-20 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_03110 57f355580ade3279af12721d58707d34 223 SUPERFAMILY SSF52172 1 120 4.98E-42 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_23710 3967e2936f9e5bb2811e6433b4b29252 69 Pfam PF14098 Small, acid-soluble spore protein I 3 67 2.8E-30 T 01-11-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 MLA2C4_23710 3967e2936f9e5bb2811e6433b4b29252 69 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 1.5E-36 T 01-11-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 MLA2C4_23710 3967e2936f9e5bb2811e6433b4b29252 69 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 22.058 T 01-11-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 MLA2C4_21440 c001784c363f7b86bcc5a70306d20571 304 Gene3D G3DSA:3.20.20.100 1 296 2.6E-106 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_21440 c001784c363f7b86bcc5a70306d20571 304 SUPERFAMILY SSF51430 1 297 1.44E-78 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_21440 c001784c363f7b86bcc5a70306d20571 304 Pfam PF00248 Aldo/keto reductase family 15 295 9.9E-66 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_21440 c001784c363f7b86bcc5a70306d20571 304 PRINTS PR00069 Aldo-keto reductase signature 37 61 7.0E-7 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21440 c001784c363f7b86bcc5a70306d20571 304 PRINTS PR00069 Aldo-keto reductase signature 103 121 7.0E-7 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21440 c001784c363f7b86bcc5a70306d20571 304 PRINTS PR00069 Aldo-keto reductase signature 134 151 7.0E-7 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_18350 197a8bfa3d9a3f3998e8419ec7e915f5 303 Pfam PF04294 VanW like protein 172 299 3.7E-45 T 01-11-2018 IPR007391 Vancomycin resistance VanW MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 3.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 376 3.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 362 3.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 3.3E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 SMART SM00387 311 423 4.3E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 Gene3D G3DSA:3.30.565.10 271 422 6.8E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 318 421 2.3E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09155 6dfbfb297facf9267c781285068d0b4d 429 SUPERFAMILY SSF55874 277 420 1.83E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_20450 11ecf97d516d03eee55600b363407924 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 59 4.3E-5 T 01-11-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20450 11ecf97d516d03eee55600b363407924 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 320 1.8E-120 T 01-11-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20450 11ecf97d516d03eee55600b363407924 324 Pfam PF00953 Glycosyl transferase family 4 83 248 1.0E-37 T 01-11-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MLA2C4_20450 11ecf97d516d03eee55600b363407924 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 01-11-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20450 11ecf97d516d03eee55600b363407924 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.192 T 01-11-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_17555 2c480c556a2b372e689cba937970e5ba 829 Pfam PF02687 FtsX-like permease family 274 367 4.3E-12 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_17555 2c480c556a2b372e689cba937970e5ba 829 Pfam PF12704 MacB-like periplasmic core domain 23 220 1.3E-8 T 01-11-2018 IPR025857 MacB-like periplasmic core domain MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 Gene3D G3DSA:3.40.50.880 1 195 3.0E-70 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 185 2.3E-91 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 2.3E-72 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.2 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 PIRSF PIRSF005639 1 191 8.3E-75 T 01-11-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 01-11-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 MLA2C4_00080 a1f79a763dbc5c53c47239c0b52e4223 196 SUPERFAMILY SSF52317 2 189 1.4E-53 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 766 3.2E-65 T 01-11-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 Pfam PF01368 DHH family 83 209 1.8E-9 T 01-11-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 Gene3D G3DSA:3.90.1640.30 57 318 2.5E-95 T 01-11-2018 MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 SUPERFAMILY SSF64182 57 452 3.66E-122 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 Pfam PF02272 DHHA1 domain 315 439 2.1E-20 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 29 562 4.2E-183 T 01-11-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MLA2C4_22990 e536a2203a41a03f75cfe2887d5854ae 779 Gene3D G3DSA:3.10.310.30 320 444 6.8E-35 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 Gene3D G3DSA:3.40.30.120 396 537 7.1E-36 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 Pfam PF01494 FAD binding domain 5 368 3.6E-98 T 01-11-2018 IPR002938 FAD-binding domain GO:0071949 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 SUPERFAMILY SSF51905 5 373 3.46E-52 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 Gene3D G3DSA:3.30.9.50 74 301 3.0E-106 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.9E-42 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 2.9E-42 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 355 371 2.9E-42 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 2.9E-42 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 2.9E-42 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 355 2.9E-42 T 01-11-2018 MLA2C4_18190 a1eb04e454aaf07b4ec73bcecf49472c 539 Gene3D G3DSA:3.50.50.60 7 363 3.0E-106 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 01-11-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 Gene3D G3DSA:3.40.50.1100 45 144 9.1E-119 T 01-11-2018 MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 SUPERFAMILY SSF53686 2 303 8.51E-100 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 1.1E-126 T 01-11-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 Gene3D G3DSA:3.40.50.1100 6 300 9.1E-119 T 01-11-2018 MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 4.0E-68 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_09355 af69eb4ed87f531ff72ed7eea0571fa0 305 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 2.9E-134 T 01-11-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MLA2C4_16405 dec66739adb4543b6f0dd211f330fd67 213 Gene3D G3DSA:3.40.1440.10 8 100 2.0E-12 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_16405 dec66739adb4543b6f0dd211f330fd67 213 SMART SM00465 20 121 0.0045 T 01-11-2018 IPR000305 GIY-YIG endonuclease MLA2C4_16405 dec66739adb4543b6f0dd211f330fd67 213 SUPERFAMILY SSF82771 21 82 6.54E-9 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 SUPERFAMILY SSF143865 5 253 4.18E-57 T 01-11-2018 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 Gene3D G3DSA:1.20.58.340 243 319 5.5E-30 T 01-11-2018 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 Gene3D G3DSA:3.30.460.20 6 129 1.3E-27 T 01-11-2018 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 10 319 2.1E-87 T 01-11-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 Gene3D G3DSA:1.20.58.340 130 241 1.0E-25 T 01-11-2018 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 SUPERFAMILY SSF144083 255 316 5.23E-21 T 01-11-2018 MLA2C4_21375 f6f00752cce076030ecd3ef5a0e69227 320 Pfam PF01544 CorA-like Mg2+ transporter protein 33 315 1.5E-74 T 01-11-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MLA2C4_24730 841bfc0ef1d9b17c66e1810c0ec42450 215 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_24730 841bfc0ef1d9b17c66e1810c0ec42450 215 SMART SM00382 29 210 7.7E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_24730 841bfc0ef1d9b17c66e1810c0ec42450 215 SUPERFAMILY SSF52540 3 207 1.05E-47 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_24730 841bfc0ef1d9b17c66e1810c0ec42450 215 Pfam PF00005 ABC transporter 20 160 3.4E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_24730 841bfc0ef1d9b17c66e1810c0ec42450 215 Gene3D G3DSA:3.40.50.300 2 213 2.1E-49 T 01-11-2018 MLA2C4_04860 68f772c2463d344d9597923618809662 317 Gene3D G3DSA:3.40.50.150 154 317 1.6E-20 T 01-11-2018 MLA2C4_04860 68f772c2463d344d9597923618809662 317 SUPERFAMILY SSF53335 157 255 9.49E-17 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_04860 68f772c2463d344d9597923618809662 317 Pfam PF01170 Putative RNA methylase family UPF0020 158 262 9.6E-7 T 01-11-2018 IPR000241 Putative RNA methylase domain MLA2C4_02455 4cfc784992684170e75487efc456c1bb 289 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 278 4.3E-55 T 01-11-2018 IPR017039 Virulence factor BrkB MLA2C4_02455 4cfc784992684170e75487efc456c1bb 289 Pfam PF03631 Virulence factor BrkB 26 277 1.5E-66 T 01-11-2018 IPR017039 Virulence factor BrkB MLA2C4_02455 4cfc784992684170e75487efc456c1bb 289 PIRSF PIRSF035875 1 289 1.8E-92 T 01-11-2018 IPR017039 Virulence factor BrkB MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 SMART SM00304 598 654 11.0 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 SMART SM00304 301 353 1.0E-14 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Pfam PF00672 HAMP domain 302 349 2.3E-15 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 609 1.6E-46 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 SMART SM00283 382 657 6.0E-79 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 SUPERFAMILY SSF58104 321 657 4.71E-74 T 01-11-2018 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Pfam PF02743 Cache domain 46 263 8.8E-27 T 01-11-2018 IPR033479 Double Cache domain 1 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Gene3D G3DSA:1.10.287.950 357 657 5.2E-70 T 01-11-2018 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 SUPERFAMILY SSF103190 90 188 4.32E-12 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Gene3D G3DSA:3.30.450.20 70 181 2.7E-37 T 01-11-2018 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Gene3D G3DSA:1.10.8.500 301 352 1.1E-9 T 01-11-2018 MLA2C4_02990 797dc3446fa815c53131b6749e3c08b9 658 Gene3D G3DSA:3.30.450.20 59 271 2.7E-37 T 01-11-2018 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 989 1.8E-52 T 01-11-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Gene3D G3DSA:1.10.40.90 363 405 4.5E-23 T 01-11-2018 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 5.9E-37 T 01-11-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Gene3D G3DSA:1.10.132.30 660 794 4.5E-59 T 01-11-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1180 0.0 T 01-11-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 760 5.4E-15 T 01-11-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF04998 RNA polymerase Rpb1, domain 5 994 1128 4.6E-14 T 01-11-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 383 3.6E-9 T 01-11-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF00623 RNA polymerase Rpb1, domain 2 381 474 2.5E-29 T 01-11-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 2.6E-89 T 01-11-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Gene3D G3DSA:1.10.150.390 1129 1190 4.2E-29 T 01-11-2018 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.718 T 01-11-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Gene3D G3DSA:1.10.1790.20 950 1127 1.8E-66 T 01-11-2018 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 SMART SM00663 224 503 8.3E-186 T 01-11-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Gene3D G3DSA:2.40.50.100 966 1028 1.8E-66 T 01-11-2018 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 SUPERFAMILY SSF64484 5 1180 0.0 T 01-11-2018 MLA2C4_00635 8e09cae487813b505c4c1ba6b3dfe5a1 1203 Gene3D G3DSA:1.10.274.100 479 659 1.6E-47 T 01-11-2018 MLA2C4_02580 c389eed9db2f77e7f04b3bc4db86b77f 217 Gene3D G3DSA:1.10.260.40 10 144 6.8E-14 T 01-11-2018 MLA2C4_02580 c389eed9db2f77e7f04b3bc4db86b77f 217 SUPERFAMILY SSF47413 7 76 2.28E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_02580 c389eed9db2f77e7f04b3bc4db86b77f 217 Pfam PF01381 Helix-turn-helix 14 68 8.4E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_02580 c389eed9db2f77e7f04b3bc4db86b77f 217 SMART SM00530 13 68 6.8E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_02580 c389eed9db2f77e7f04b3bc4db86b77f 217 Pfam PF06803 Protein of unknown function (DUF1232) 170 203 1.6E-11 T 01-11-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 MLA2C4_21015 af75ef846446e1e999fe676123572420 143 Pfam PF13162 Protein of unknown function (DUF3997) 28 132 8.2E-38 T 01-11-2018 IPR025059 Protein of unknown function DUF3997 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 01-11-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 SUPERFAMILY SSF102114 6 305 1.83E-82 T 01-11-2018 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 337 1.7E-120 T 01-11-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 316 4.9E-39 T 01-11-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 Pfam PF04055 Radical SAM superfamily 19 180 4.1E-30 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 Pfam PF13353 4Fe-4S single cluster domain 21 103 1.1E-6 T 01-11-2018 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 SMART SM00729 14 222 6.1E-15 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 337 41.183 T 01-11-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24580 42cb88cf4ea778b6c37ebe71116e66a2 337 Gene3D G3DSA:3.20.20.70 2 337 7.4E-107 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_10715 b3596cac750ed705d775184740e9f6da 226 SUPERFAMILY SSF53335 10 195 1.81E-39 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_10715 b3596cac750ed705d775184740e9f6da 226 Gene3D G3DSA:3.40.50.150 26 226 3.3E-62 T 01-11-2018 MLA2C4_10715 b3596cac750ed705d775184740e9f6da 226 Pfam PF08241 Methyltransferase domain 52 144 1.9E-22 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SUPERFAMILY SSF55073 151 304 1.1E-46 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 Pfam PF00563 EAL domain 319 553 5.8E-71 T 01-11-2018 IPR001633 EAL domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SMART SM00052 312 558 4.4E-99 T 01-11-2018 IPR001633 EAL domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SUPERFAMILY SSF141868 319 563 3.27E-85 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SMART SM00267 135 302 4.7E-56 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 Pfam PF00990 Diguanylate cyclase, GGDEF domain 146 297 2.9E-42 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 Gene3D G3DSA:3.30.450.20 12 144 2.0E-35 T 01-11-2018 MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 299 4.8E-36 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 Pfam PF13426 PAS domain 26 126 1.0E-15 T 01-11-2018 IPR000014 PAS domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SMART SM00091 14 83 0.0075 T 01-11-2018 IPR000014 PAS domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 Gene3D G3DSA:3.20.20.450 316 566 6.8E-92 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 135 6.9E-19 T 01-11-2018 IPR000014 PAS domain MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 Gene3D G3DSA:3.30.70.270 145 315 1.1E-56 T 01-11-2018 MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SUPERFAMILY SSF55785 26 125 6.63E-31 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_03305 7b853187e6ecb9cb1732c5828f02d567 567 SMART SM00086 86 128 7.5E-10 T 01-11-2018 IPR001610 PAC motif MLA2C4_00955 a8d1b07315fefbae2e02913f65e12e7b 273 Gene3D G3DSA:3.40.1700.10 101 254 2.2E-60 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MLA2C4_00955 a8d1b07315fefbae2e02913f65e12e7b 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 3 255 1.1E-95 T 01-11-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 MLA2C4_00955 a8d1b07315fefbae2e02913f65e12e7b 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 236 9.3E-44 T 01-11-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MLA2C4_00955 a8d1b07315fefbae2e02913f65e12e7b 273 SUPERFAMILY SSF143597 40 240 1.57E-69 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MLA2C4_00955 a8d1b07315fefbae2e02913f65e12e7b 273 PIRSF PIRSF004793 3 269 1.4E-98 T 01-11-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 MLA2C4_00955 a8d1b07315fefbae2e02913f65e12e7b 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 254 33.678 T 01-11-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 Gene3D G3DSA:1.10.390.10 427 590 6.4E-61 T 01-11-2018 IPR027268 Peptidase M4/M1, CTD superfamily MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 268 422 3.2E-45 T 01-11-2018 IPR013856 Peptidase M4 domain GO:0004222 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 SUPERFAMILY SSF55486 267 591 1.68E-89 T 01-11-2018 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 Pfam PF03413 Peptidase propeptide and YPEB domain 189 261 2.5E-11 T 01-11-2018 IPR025711 PepSY domain MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 425 590 4.4E-59 T 01-11-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 377 397 9.6E-26 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 413 429 9.6E-26 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 434 445 9.6E-26 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 505 521 9.6E-26 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 124 174 1.8E-13 T 01-11-2018 IPR011096 FTP domain MLA2C4_26250 b8d666abd7a935e3a163b95c0467399c 591 Gene3D G3DSA:3.10.170.10 267 426 6.2E-52 T 01-11-2018 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 4 201 1.2E-58 T 01-11-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Pfam PF07499 RuvA, C-terminal domain 158 200 5.1E-12 T 01-11-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Gene3D G3DSA:1.10.8.10 154 200 9.3E-9 T 01-11-2018 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Pfam PF14520 Helix-hairpin-helix domain 70 127 3.6E-15 T 01-11-2018 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Gene3D G3DSA:1.10.150.20 65 140 6.9E-24 T 01-11-2018 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 SUPERFAMILY SSF46929 158 200 4.32E-10 T 01-11-2018 IPR036267 RuvA, C-terminal domain superfamily MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 SUPERFAMILY SSF50249 1 61 1.09E-14 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 SMART SM00278 106 125 2.1 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 SMART SM00278 71 90 0.38 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 SUPERFAMILY SSF47781 63 135 1.6E-20 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 30.188 T 01-11-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Pfam PF01330 RuvA N terminal domain 2 60 1.4E-18 T 01-11-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MLA2C4_23050 df3a802bb61c165a3319c2b5a425f90d 205 Gene3D G3DSA:2.40.50.140 1 63 5.5E-16 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 24 692 0.0 T 01-11-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 5.4E-26 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 489 5.4E-26 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 5.4E-26 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 5.4E-26 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 321 335 5.4E-26 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 468 5.4E-26 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 SUPERFAMILY SSF81653 127 223 3.4E-22 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 SUPERFAMILY SSF56784 309 575 1.46E-41 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 Gene3D G3DSA:2.70.150.20 122 227 3.7E-27 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 SUPERFAMILY SSF81665 51 670 4.84E-13 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 Pfam PF00122 E1-E2 ATPase 125 300 1.0E-34 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 Gene3D G3DSA:3.40.1110.10 332 462 1.4E-45 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 Gene3D G3DSA:3.40.50.1000 463 580 1.0E-27 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 28 696 39.904 T 01-11-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 346 2.2E-32 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 384 617 4.2E-49 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 Pfam PF00702 haloacid dehalogenase-like hydrolase 317 546 2.6E-38 T 01-11-2018 MLA2C4_03995 d3b67005b76f4f839ca4871dfd887b33 696 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 323 329 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_23395 09ea3428a18c5c66991eef2e2a0c74b5 212 Gene3D G3DSA:1.10.357.10 13 179 9.1E-18 T 01-11-2018 MLA2C4_23395 09ea3428a18c5c66991eef2e2a0c74b5 212 SUPERFAMILY SSF46689 12 66 2.89E-10 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_23395 09ea3428a18c5c66991eef2e2a0c74b5 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 56 1.7E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 SMART SM00382 468 650 5.4E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 SMART SM00843 724 789 6.0E-40 T 01-11-2018 IPR018541 FtsK gamma domain MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 SUPERFAMILY SSF52540 406 701 1.58E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 Pfam PF09397 Ftsk gamma domain 727 786 2.5E-30 T 01-11-2018 IPR018541 FtsK gamma domain MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 Gene3D G3DSA:1.10.10.10 721 785 5.7E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 Gene3D G3DSA:3.40.50.300 430 715 1.4E-111 T 01-11-2018 MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 SUPERFAMILY SSF46785 725 787 5.98E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 Gene3D G3DSA:3.30.980.40 325 428 5.1E-38 T 01-11-2018 MLA2C4_19845 699a713c01a727ec3979290896be1a38 794 Pfam PF01580 FtsK/SpoIIIE family 433 629 3.2E-65 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 SMART SM00922 143 241 8.6E-25 T 01-11-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 SUPERFAMILY SSF51604 130 342 1.31E-63 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 127 1.6E-19 T 01-11-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 Gene3D G3DSA:3.20.20.120 119 333 2.4E-109 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 Gene3D G3DSA:3.30.390.10 9 118 2.4E-109 T 01-11-2018 IPR029017 Enolase-like, N-terminal MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 Pfam PF13378 Enolase C-terminal domain-like 146 329 1.3E-48 T 01-11-2018 IPR029065 Enolase C-terminal domain-like MLA2C4_15080 25178930d07dd115d0f2b0e9b8071da2 353 SUPERFAMILY SSF54826 4 128 2.0E-29 T 01-11-2018 MLA2C4_11640 2e0747bc7fc6958c89672da3c9d1d1ba 230 Gene3D G3DSA:3.40.50.300 8 216 6.5E-36 T 01-11-2018 MLA2C4_11640 2e0747bc7fc6958c89672da3c9d1d1ba 230 SUPERFAMILY SSF52540 95 200 2.2E-12 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11640 2e0747bc7fc6958c89672da3c9d1d1ba 230 Pfam PF01695 IstB-like ATP binding protein 96 193 2.9E-13 T 01-11-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 PIRSF PIRSF007165 1 178 4.2E-82 T 01-11-2018 IPR011188 Uncharacterised protein family UPF0302 MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 Pfam PF08858 IDEAL domain 139 175 1.7E-15 T 01-11-2018 IPR014957 IDEAL domain MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 Gene3D G3DSA:1.20.1440.290 1 123 2.4E-56 T 01-11-2018 IPR038091 UPF0302, N-terminal domain superfamily MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 SMART SM00914 139 175 6.7E-14 T 01-11-2018 IPR014957 IDEAL domain MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 Gene3D G3DSA:4.10.810.10 124 178 5.7E-26 T 01-11-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 Pfam PF08864 UPF0302 domain 9 113 5.7E-47 T 01-11-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal MLA2C4_07995 a1eba6edba7bad9463f1b4726455c7f5 178 Hamap MF_00760 UPF0302 protein . 2 178 33.249 T 01-11-2018 IPR011188 Uncharacterised protein family UPF0302 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SUPERFAMILY SSF46955 412 483 2.93E-17 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 805 1.1E-267 T 01-11-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 799 46.571 T 01-11-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Pfam PF03483 B3/4 domain 222 394 2.8E-67 T 01-11-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Gene3D G3DSA:2.40.50.140 40 161 1.2E-68 T 01-11-2018 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Gene3D G3DSA:3.30.930.10 495 699 4.7E-61 T 01-11-2018 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SUPERFAMILY SSF55681 475 695 4.67E-51 T 01-11-2018 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Pfam PF03147 Ferredoxin-fold anticodon binding domain 712 805 6.3E-31 T 01-11-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SUPERFAMILY SSF54991 708 805 2.09E-32 T 01-11-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Pfam PF01588 Putative tRNA binding domain 46 152 8.7E-27 T 01-11-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Gene3D G3DSA:3.50.40.10 204 405 5.9E-83 T 01-11-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SMART SM00896 712 805 4.0E-46 T 01-11-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SMART SM00874 411 479 1.3E-24 T 01-11-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Gene3D G3DSA:3.30.56.10 410 483 2.1E-23 T 01-11-2018 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Gene3D G3DSA:3.30.56.10 4 189 1.2E-68 T 01-11-2018 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SUPERFAMILY SSF56037 208 405 8.63E-72 T 01-11-2018 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Gene3D G3DSA:3.30.70.380 713 806 2.7E-32 T 01-11-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SUPERFAMILY SSF50249 36 199 5.39E-49 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 SMART SM00873 221 394 6.7E-92 T 01-11-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MLA2C4_23695 7f5ffec7238d5196d2ba8bc421f6a3fc 806 Pfam PF03484 tRNA synthetase B5 domain 414 479 5.1E-17 T 01-11-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MLA2C4_27615 a7609c4f982493499917170b10a4bb92 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 321 3.7E-155 T 01-11-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MLA2C4_27615 a7609c4f982493499917170b10a4bb92 321 SUPERFAMILY SSF56655 2 313 1.53E-112 T 01-11-2018 MLA2C4_27615 a7609c4f982493499917170b10a4bb92 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 310 1.1E-144 T 01-11-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MLA2C4_27615 a7609c4f982493499917170b10a4bb92 321 PIRSF PIRSF004532 1 321 1.0E-151 T 01-11-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MLA2C4_27615 a7609c4f982493499917170b10a4bb92 321 Gene3D G3DSA:3.30.540.10 7 310 7.8E-136 T 01-11-2018 MLA2C4_27615 a7609c4f982493499917170b10a4bb92 321 Gene3D G3DSA:3.40.190.90 122 284 7.8E-136 T 01-11-2018 MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 SUPERFAMILY SSF52540 2 212 5.43E-42 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 183 5.7E-56 T 01-11-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 Gene3D G3DSA:3.40.50.300 1 202 8.3E-73 T 01-11-2018 MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 SMART SM00833 221 315 1.2E-7 T 01-11-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 221 315 3.6E-22 T 01-11-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 SUPERFAMILY SSF90002 221 315 3.14E-25 T 01-11-2018 MLA2C4_10295 5ca73e7aa925fde36efe95210b037c3a 316 Gene3D G3DSA:3.30.1220.10 204 316 2.6E-35 T 01-11-2018 IPR036627 CobW-like, C-terminal domain superfamily MLA2C4_22855 51b292f5f5ea5533929da2ebf6b4c79e 426 Gene3D G3DSA:2.40.30.10 336 423 9.8E-40 T 01-11-2018 MLA2C4_22855 51b292f5f5ea5533929da2ebf6b4c79e 426 Pfam PF16325 Peptidase family U32 C-terminal domain 340 421 5.3E-27 T 01-11-2018 IPR032525 Peptidase family U32, C-terminal MLA2C4_22855 51b292f5f5ea5533929da2ebf6b4c79e 426 ProSitePatterns PS01276 Peptidase family U32 signature. 177 195 - T 01-11-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MLA2C4_22855 51b292f5f5ea5533929da2ebf6b4c79e 426 Pfam PF01136 Peptidase family U32 91 325 1.8E-84 T 01-11-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MLA2C4_23105 edd83b186963fd7e6c46b5ae696ea99d 380 Gene3D G3DSA:1.10.260.50 14 275 4.2E-122 T 01-11-2018 MLA2C4_23105 edd83b186963fd7e6c46b5ae696ea99d 380 PIRSF PIRSF005572 1 376 7.6E-117 T 01-11-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MLA2C4_23105 edd83b186963fd7e6c46b5ae696ea99d 380 Pfam PF00266 Aminotransferase class-V 3 361 1.8E-73 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_23105 edd83b186963fd7e6c46b5ae696ea99d 380 SUPERFAMILY SSF53383 2 370 2.21E-94 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_23105 edd83b186963fd7e6c46b5ae696ea99d 380 Gene3D G3DSA:3.90.1150.10 3 367 4.2E-122 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_23105 edd83b186963fd7e6c46b5ae696ea99d 380 Gene3D G3DSA:3.40.640.10 60 232 4.2E-122 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_15650 c882d2e30d004d51237225c90e51503f 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 4.2E-240 T 01-11-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MLA2C4_15650 c882d2e30d004d51237225c90e51503f 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 3.6E-217 T 01-11-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MLA2C4_15650 c882d2e30d004d51237225c90e51503f 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.205 T 01-11-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 MLA2C4_15650 c882d2e30d004d51237225c90e51503f 500 SUPERFAMILY SSF51905 4 274 5.18E-23 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 SUPERFAMILY SSF56784 1 267 1.58E-77 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 Gene3D G3DSA:3.40.50.1000 4 263 1.9E-88 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 1.6E-28 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 01-11-2018 MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 8.8E-72 T 01-11-2018 MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 Gene3D G3DSA:3.30.1240.10 87 191 1.9E-88 T 01-11-2018 MLA2C4_27960 ad646328c4461ba52b1eeb37b7b436ad 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 261 4.2E-69 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 SUPERFAMILY SSF51735 136 303 3.19E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 SMART SM01003 4 136 3.1E-78 T 01-11-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 5.0E-83 T 01-11-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 7.1E-47 T 01-11-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 SUPERFAMILY SSF52283 1 360 9.35E-69 T 01-11-2018 MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 01-11-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 SMART SM01002 148 297 6.6E-90 T 01-11-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.7E-181 T 01-11-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 Gene3D G3DSA:3.40.50.720 129 305 7.4E-141 T 01-11-2018 MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 PIRSF PIRSF000183 1 371 1.2E-192 T 01-11-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MLA2C4_24025 53a2685e361853e402fe4f2cbc72c363 377 Gene3D G3DSA:3.40.50.720 3 353 7.4E-141 T 01-11-2018 MLA2C4_08570 8346665e51dd7d08fcf1c85ebe00854c 432 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 383 427 2.8E-10 T 01-11-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MLA2C4_08570 8346665e51dd7d08fcf1c85ebe00854c 432 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 428 2.0E-80 T 01-11-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MLA2C4_08570 8346665e51dd7d08fcf1c85ebe00854c 432 SUPERFAMILY SSF64518 134 432 1.44E-15 T 01-11-2018 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 PIRSF PIRSF000429 1 362 3.3E-113 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 Gene3D G3DSA:3.40.47.10 5 244 3.9E-121 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 359 1.6E-114 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 SUPERFAMILY SSF53901 4 237 7.02E-52 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 Gene3D G3DSA:3.40.47.10 121 357 3.9E-121 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 SUPERFAMILY SSF53901 239 359 8.97E-37 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 ProSitePatterns PS00737 Thiolases signature 2. 307 323 - T 01-11-2018 IPR020613 Thiolase, conserved site GO:0016747 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 Pfam PF00108 Thiolase, N-terminal domain 5 230 1.5E-49 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 MLA2C4_18860 5dcfcefca117dad96b75e905a4aed6c9 363 Pfam PF02803 Thiolase, C-terminal domain 239 360 9.1E-38 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 MLA2C4_23030 09fe71fd1d2ac0b929f0a24e40b218dc 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 373 2.3E-184 T 01-11-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MLA2C4_23030 09fe71fd1d2ac0b929f0a24e40b218dc 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.288 T 01-11-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MLA2C4_23030 09fe71fd1d2ac0b929f0a24e40b218dc 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 373 2.5E-173 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MLA2C4_23030 09fe71fd1d2ac0b929f0a24e40b218dc 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 4.0E-92 T 01-11-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MLA2C4_23030 09fe71fd1d2ac0b929f0a24e40b218dc 379 Gene3D G3DSA:3.20.20.105 1 373 6.0E-170 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MLA2C4_23030 09fe71fd1d2ac0b929f0a24e40b218dc 379 SUPERFAMILY SSF51713 2 369 7.32E-161 T 01-11-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 Gene3D G3DSA:3.40.50.620 4 323 4.7E-140 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 Gene3D G3DSA:1.10.240.10 183 293 4.7E-140 T 01-11-2018 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 SUPERFAMILY SSF52374 3 324 5.63E-100 T 01-11-2018 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 42.864 T 01-11-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 Pfam PF00579 tRNA synthetases class I (W and Y) 3 277 2.0E-84 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 3.0E-29 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 3.0E-29 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 3.0E-29 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 3.0E-29 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_06200 338ee4635220d9cfea94d9f2456fe18a 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 324 5.7E-118 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 Gene3D G3DSA:3.40.605.10 39 502 1.8E-186 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 2.6E-249 T 01-11-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 SUPERFAMILY SSF53720 4 511 7.07E-154 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 74.215 T 01-11-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 Pfam PF00171 Aldehyde dehydrogenase family 50 510 6.7E-154 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 Gene3D G3DSA:3.40.309.10 289 479 1.8E-186 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 01-11-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MLA2C4_01850 612d391fed4e164a629701eabe599257 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 01-11-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MLA2C4_19780 5bb4c3dac63e113374cba8c6be7f7c05 192 PIRSF PIRSF000847 1 192 7.7E-52 T 01-11-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MLA2C4_19780 5bb4c3dac63e113374cba8c6be7f7c05 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MLA2C4_19780 5bb4c3dac63e113374cba8c6be7f7c05 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 1.3E-17 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MLA2C4_19780 5bb4c3dac63e113374cba8c6be7f7c05 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 187 6.0E-64 T 01-11-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MLA2C4_19780 5bb4c3dac63e113374cba8c6be7f7c05 192 Gene3D G3DSA:1.20.120.1760 3 187 3.1E-9 T 01-11-2018 MLA2C4_14855 64c50e8238d53b6496a614820aa06fb3 258 Pfam PF13354 Beta-lactamase enzyme family 29 219 1.1E-15 T 01-11-2018 MLA2C4_14855 64c50e8238d53b6496a614820aa06fb3 258 SUPERFAMILY SSF56601 1 248 3.43E-23 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_14855 64c50e8238d53b6496a614820aa06fb3 258 Gene3D G3DSA:3.40.710.10 1 251 8.8E-19 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 SUPERFAMILY SSF103473 1 524 1.83E-77 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 4.3E-11 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 4.3E-11 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 4.3E-11 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 4.3E-11 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 4.3E-11 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 Gene3D G3DSA:1.20.1720.10 12 199 6.1E-49 T 01-11-2018 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 510 1.9E-89 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 Pfam PF07690 Major Facilitator Superfamily 16 407 1.4E-54 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_03500 48c7ec72cf3d848fe8a34de420a8e3ac 537 Gene3D G3DSA:1.20.1250.20 254 425 9.4E-23 T 01-11-2018 MLA2C4_16480 d54d1539126a5b900837044529d6783a 443 Gene3D G3DSA:3.30.1870.10 104 175 3.6E-152 T 01-11-2018 MLA2C4_16480 d54d1539126a5b900837044529d6783a 443 PIRSF PIRSF036794 23 443 1.5E-159 T 01-11-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type MLA2C4_16480 d54d1539126a5b900837044529d6783a 443 Gene3D G3DSA:1.20.1440.30 176 302 3.6E-152 T 01-11-2018 MLA2C4_16480 d54d1539126a5b900837044529d6783a 443 SUPERFAMILY SSF159501 41 441 4.97E-116 T 01-11-2018 MLA2C4_16480 d54d1539126a5b900837044529d6783a 443 Gene3D G3DSA:3.40.1660.10 45 436 3.6E-152 T 01-11-2018 MLA2C4_16480 d54d1539126a5b900837044529d6783a 443 Pfam PF05139 Erythromycin esterase 102 435 2.0E-67 T 01-11-2018 IPR007815 Erythromycin esterase GO:0046677 MLA2C4_06865 14738e74edb37b9294fe2bea00e609f5 730 Gene3D G3DSA:1.20.1640.10 153 352 2.8E-11 T 01-11-2018 MLA2C4_06865 14738e74edb37b9294fe2bea00e609f5 730 Pfam PF03176 MMPL family 395 727 1.0E-38 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MLA2C4_06865 14738e74edb37b9294fe2bea00e609f5 730 Pfam PF03176 MMPL family 59 366 7.1E-48 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MLA2C4_06865 14738e74edb37b9294fe2bea00e609f5 730 SUPERFAMILY SSF82866 499 719 1.15E-32 T 01-11-2018 MLA2C4_06865 14738e74edb37b9294fe2bea00e609f5 730 SUPERFAMILY SSF82866 152 341 1.7E-31 T 01-11-2018 MLA2C4_21730 12ea0286bd37912864b2497429b9ec1f 144 Gene3D G3DSA:3.40.30.10 24 141 7.9E-53 T 01-11-2018 MLA2C4_21730 12ea0286bd37912864b2497429b9ec1f 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 141 1.5E-62 T 01-11-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family MLA2C4_21730 12ea0286bd37912864b2497429b9ec1f 144 Pfam PF06491 Disulphide isomerase 7 141 2.8E-61 T 01-11-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 199 1.8E-8 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 Gene3D G3DSA:3.40.50.1000 5 221 1.6E-70 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 1.3E-7 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.3E-7 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 1.3E-7 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 1.3E-7 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 1.7E-66 T 01-11-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 81 191 3.3E-17 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 SUPERFAMILY SSF56784 2 226 1.58E-47 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 2.7E-27 T 01-11-2018 MLA2C4_17495 a2d3ffcae9c3faaf7c48c29165aa169d 236 Gene3D G3DSA:1.10.150.240 16 100 1.6E-70 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 Pfam PF00501 AMP-binding enzyme 96 521 4.5E-75 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 530 608 2.8E-22 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 Gene3D G3DSA:3.40.50.12780 58 515 1.5E-90 T 01-11-2018 MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 84 1.5E-12 T 01-11-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 Gene3D G3DSA:3.30.300.30 517 642 2.3E-21 T 01-11-2018 MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 264 275 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_13490 f41b2f1c7500940885ead4beccc32339 646 SUPERFAMILY SSF56801 17 635 1.44E-153 T 01-11-2018 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 SUPERFAMILY SSF69336 1182 1474 2.09E-44 T 01-11-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Gene3D G3DSA:2.160.20.60 1197 1478 1.5E-59 T 01-11-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Gene3D G3DSA:3.60.20.10 24 535 0.0 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Pfam PF01645 Conserved region in glutamate synthase 791 1109 4.1E-100 T 01-11-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Pfam PF01493 GXGXG motif 1230 1402 3.2E-20 T 01-11-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Gene3D G3DSA:3.20.20.70 474 1166 0.0 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Gene3D G3DSA:3.20.20.70 425 776 0.0 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 SUPERFAMILY SSF56235 24 400 8.42E-78 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Pfam PF04898 Glutamate synthase central domain 449 729 2.4E-69 T 01-11-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 SUPERFAMILY SSF51395 448 1168 2.5E-160 T 01-11-2018 MLA2C4_02750 0bf3fe0dcf8a26a2ecec9c2c1ffa9987 1478 Pfam PF00310 Glutamine amidotransferases class-II 24 392 1.3E-49 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain MLA2C4_17170 9947b1c0e92155b840cbd631e13965d7 245 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 169 228 1.9E-18 T 01-11-2018 IPR006343 DnaD domain MLA2C4_17170 9947b1c0e92155b840cbd631e13965d7 245 Pfam PF07261 Replication initiation and membrane attachment 169 228 1.9E-12 T 01-11-2018 IPR006343 DnaD domain MLA2C4_17170 9947b1c0e92155b840cbd631e13965d7 245 Gene3D G3DSA:1.10.10.630 163 230 1.7E-13 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_17170 9947b1c0e92155b840cbd631e13965d7 245 SUPERFAMILY SSF158499 168 228 6.28E-16 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_08325 9b299da1237b250d45c0832d103fbaff 186 Pfam PF00857 Isochorismatase family 4 140 1.1E-22 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_08325 9b299da1237b250d45c0832d103fbaff 186 SUPERFAMILY SSF52499 2 174 5.1E-33 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_08325 9b299da1237b250d45c0832d103fbaff 186 Gene3D G3DSA:3.40.50.850 1 164 7.3E-32 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.864 T 01-11-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 SMART SM00861 316 481 2.6E-64 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 SUPERFAMILY SSF52518 5 378 1.0E-73 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 Pfam PF02780 Transketolase, C-terminal domain 493 615 4.3E-30 T 01-11-2018 IPR033248 Transketolase, C-terminal domain MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 1.8E-38 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 01-11-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 Gene3D G3DSA:3.40.50.920 493 627 1.5E-37 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 01-11-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 SUPERFAMILY SSF52922 490 623 1.22E-32 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 5.4E-295 T 01-11-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 1.5E-118 T 01-11-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 Gene3D G3DSA:3.40.50.970 314 489 8.4E-66 T 01-11-2018 MLA2C4_21850 4fac9dd238bf36f0e74eeba5a7d9bd5b 630 SUPERFAMILY SSF52518 317 502 6.81E-53 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_02340 73fa7655da1363d0698419327b746a42 104 Pfam PF00085 Thioredoxin 13 99 3.5E-5 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 MLA2C4_02340 73fa7655da1363d0698419327b746a42 104 SUPERFAMILY SSF52833 5 100 1.8E-15 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_02340 73fa7655da1363d0698419327b746a42 104 Gene3D G3DSA:3.40.30.10 1 104 2.2E-21 T 01-11-2018 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 SUPERFAMILY SSF52518 4 183 2.28E-62 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 Gene3D G3DSA:3.40.50.970 1 184 8.9E-71 T 01-11-2018 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 SUPERFAMILY SSF52518 368 561 2.09E-65 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 Gene3D G3DSA:3.40.50.970 361 539 1.0E-125 T 01-11-2018 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 Gene3D G3DSA:3.40.50.1220 200 360 1.0E-125 T 01-11-2018 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 333 6.6E-43 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 SUPERFAMILY SSF52467 191 360 2.36E-58 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 173 3.6E-58 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 01-11-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 539 3.6E-49 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_07390 c59f453ac7d227b5d84ae84eb9dc4553 566 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 11 561 2.1E-253 T 01-11-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 410 1.2E-151 T 01-11-2018 IPR008135 Competence-induced protein CinA MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 SUPERFAMILY SSF53218 1 205 5.23E-40 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 164 9.1E-33 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 Gene3D G3DSA:3.90.950.20 252 412 8.7E-48 T 01-11-2018 IPR036653 CinA-like, C-terminal MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 PIRSF PIRSF006728 1 412 4.5E-165 T 01-11-2018 IPR008135 Competence-induced protein CinA MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 Gene3D G3DSA:3.40.980.10 1 169 5.6E-49 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 Pfam PF00994 Probable molybdopterin binding domain 4 169 1.1E-35 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 Pfam PF02464 Competence-damaged protein 258 408 8.0E-50 T 01-11-2018 IPR008136 CinA, C-terminal MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 412 164.743 T 01-11-2018 IPR008135 Competence-induced protein CinA MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 265 409 1.1E-41 T 01-11-2018 IPR008136 CinA, C-terminal MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 SUPERFAMILY SSF142433 249 410 9.94E-46 T 01-11-2018 IPR036653 CinA-like, C-terminal MLA2C4_19775 7e0b161d541e4b9e13755187c215ae01 412 SMART SM00852 4 170 8.9E-41 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_09810 67a788cc0a487b629ff4bc9f01e23e4f 405 Gene3D G3DSA:3.40.50.2300 161 378 5.7E-113 T 01-11-2018 MLA2C4_09810 67a788cc0a487b629ff4bc9f01e23e4f 405 Pfam PF13458 Periplasmic binding protein 39 377 8.1E-71 T 01-11-2018 IPR028081 Leucine-binding protein domain MLA2C4_09810 67a788cc0a487b629ff4bc9f01e23e4f 405 SUPERFAMILY SSF53822 39 385 1.36E-80 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_09810 67a788cc0a487b629ff4bc9f01e23e4f 405 Gene3D G3DSA:3.40.50.2300 49 371 5.7E-113 T 01-11-2018 MLA2C4_24685 9c1a1b9af63f16b629b620e59f6de17a 340 Pfam PF04235 Protein of unknown function (DUF418) 165 333 3.0E-30 T 01-11-2018 IPR007349 Domain of unknown function DUF418 MLA2C4_24685 9c1a1b9af63f16b629b620e59f6de17a 340 Pfam PF07786 Protein of unknown function (DUF1624) 9 158 1.7E-6 T 01-11-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 01-11-2018 MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 SUPERFAMILY SSF56784 2 284 5.35E-69 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 ProSitePatterns PS01229 Hypothetical cof family signature 2. 232 254 - T 01-11-2018 MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 278 1.8E-57 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 Gene3D G3DSA:3.40.50.1000 2 275 2.2E-80 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 251 1.5E-26 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 Gene3D G3DSA:3.30.1240.10 80 207 2.2E-80 T 01-11-2018 MLA2C4_01320 95ba6511f9b429ac885853295da532a7 290 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 278 1.8E-66 T 01-11-2018 MLA2C4_05210 cc2b08ddbaf5d7dcfbca8530b9216548 183 Pfam PF11611 Domain of unknown function (DUF4352) 77 165 3.8E-8 T 01-11-2018 IPR029051 Domain of unknown function DUF4352 MLA2C4_05210 cc2b08ddbaf5d7dcfbca8530b9216548 183 Gene3D G3DSA:2.60.40.1240 65 177 5.4E-11 T 01-11-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily MLA2C4_17150 4d00e6ed3f2f86b89f230417edce674f 445 Gene3D G3DSA:3.40.1660.10 45 441 1.5E-136 T 01-11-2018 MLA2C4_17150 4d00e6ed3f2f86b89f230417edce674f 445 SUPERFAMILY SSF159501 36 444 4.45E-107 T 01-11-2018 MLA2C4_17150 4d00e6ed3f2f86b89f230417edce674f 445 Gene3D G3DSA:1.20.1440.30 175 302 1.5E-136 T 01-11-2018 MLA2C4_17150 4d00e6ed3f2f86b89f230417edce674f 445 PIRSF PIRSF036794 23 445 6.1E-144 T 01-11-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type MLA2C4_17150 4d00e6ed3f2f86b89f230417edce674f 445 Pfam PF05139 Erythromycin esterase 101 439 1.2E-62 T 01-11-2018 IPR007815 Erythromycin esterase GO:0046677 MLA2C4_17150 4d00e6ed3f2f86b89f230417edce674f 445 Gene3D G3DSA:3.30.1870.10 103 174 1.5E-136 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.3E-13 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.2E-7 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.2E-7 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.5E-87 T 01-11-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 Pfam PF00117 Glutamine amidotransferase class-I 4 186 1.6E-54 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 Gene3D G3DSA:3.40.50.880 1 188 4.7E-64 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 8.0E-36 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 8.0E-36 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 8.0E-36 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 8.0E-36 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 8.0E-36 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 8.0E-36 T 01-11-2018 MLA2C4_00395 bb042444a0271ed280bca7b39e1bbb24 195 SUPERFAMILY SSF52317 1 187 5.64E-57 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SUPERFAMILY SSF81296 457 531 3.08E-10 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SUPERFAMILY SSF52058 209 440 3.4E-38 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 683 704 60.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 356 377 4.8 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 659 682 280.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 637 658 200.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 422 443 270.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 332 355 530.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 727 748 290.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 288 309 1.1 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 310 331 34.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 615 636 17.0 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00365 378 399 0.37 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Gene3D G3DSA:2.60.40.1850 40 163 4.0E-36 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SUPERFAMILY SSF52058 567 797 2.04E-37 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Gene3D G3DSA:3.80.10.10 529 744 2.2E-44 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Gene3D G3DSA:3.80.10.10 174 348 4.4E-31 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 683 708 75.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 378 401 34.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 310 332 130.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 288 309 160.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 727 748 5.7 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 637 659 23.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 422 445 200.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00369 615 636 84.0 T 01-11-2018 IPR003591 Leucine-rich repeat, typical subtype MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SUPERFAMILY SSF158911 46 161 5.36E-29 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Pfam PF05031 Iron Transport-associated domain 44 161 2.8E-29 T 01-11-2018 IPR006635 NEAT domain MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Pfam PF12799 Leucine Rich repeats (2 copies) 708 745 1.6E-6 T 01-11-2018 IPR025875 Leucine rich repeat 4 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Pfam PF12799 Leucine Rich repeats (2 copies) 290 329 4.6E-7 T 01-11-2018 IPR025875 Leucine rich repeat 4 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1132 1163 4.4E-4 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 SMART SM00725 44 168 1.2E-15 T 01-11-2018 IPR006635 NEAT domain MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Gene3D G3DSA:2.60.40.1220 434 528 1.4E-16 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Gene3D G3DSA:2.60.40.1220 761 862 3.5E-12 T 01-11-2018 MLA2C4_02960 aa118978fae3b9d3d0c7bc8b2c5c0a25 1167 Gene3D G3DSA:3.80.10.10 349 402 1.5E-7 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_15715 4919aa747ea4d8fa542ba01fe2907228 108 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 78 2.7E-15 T 01-11-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MLA2C4_15715 4919aa747ea4d8fa542ba01fe2907228 108 Gene3D G3DSA:3.30.70.100 1 108 1.7E-48 T 01-11-2018 MLA2C4_15715 4919aa747ea4d8fa542ba01fe2907228 108 SUPERFAMILY SSF54909 1 99 4.36E-22 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 Gene3D G3DSA:3.40.710.10 315 669 1.8E-227 T 01-11-2018 MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 678 2.4E-68 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 SUPERFAMILY SSF56601 315 686 1.39E-69 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 Gene3D G3DSA:1.10.10.1230 89 191 1.8E-227 T 01-11-2018 MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 Gene3D G3DSA:3.90.1310.30 64 567 1.8E-227 T 01-11-2018 MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 SUPERFAMILY SSF56519 58 315 1.57E-35 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_22335 5f4a3c93a0eff5ec5091fec281e5bf71 708 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 301 2.3E-36 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_18870 06489d21a12e1e81f93c32733c57c5ce 191 Gene3D G3DSA:1.10.1760.20 1 178 1.3E-50 T 01-11-2018 MLA2C4_18870 06489d21a12e1e81f93c32733c57c5ce 191 PIRSF PIRSF016661 1 179 6.4E-48 T 01-11-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 MLA2C4_18870 06489d21a12e1e81f93c32733c57c5ce 191 Pfam PF02632 BioY family 29 171 5.6E-36 T 01-11-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 MLA2C4_11160 20a3d4065a9fa2d7159e72a1e6412deb 211 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 1.5E-34 T 01-11-2018 MLA2C4_11160 20a3d4065a9fa2d7159e72a1e6412deb 211 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 74 177 1.2E-12 T 01-11-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MLA2C4_11160 20a3d4065a9fa2d7159e72a1e6412deb 211 Gene3D G3DSA:3.40.50.1000 5 197 3.5E-38 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_11160 20a3d4065a9fa2d7159e72a1e6412deb 211 Gene3D G3DSA:1.10.150.240 16 80 3.5E-38 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_11160 20a3d4065a9fa2d7159e72a1e6412deb 211 SUPERFAMILY SSF56784 1 207 2.98E-44 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_11160 20a3d4065a9fa2d7159e72a1e6412deb 211 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 171 1.7E-6 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_09590 46eb07b79671b0bdf432eacf827afeed 608 Gene3D G3DSA:1.20.1740.10 21 467 2.6E-24 T 01-11-2018 MLA2C4_09590 46eb07b79671b0bdf432eacf827afeed 608 Pfam PF13520 Amino acid permease 29 444 1.3E-32 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_16340 582c596de7888c5dfdcfe5cc9973ad73 284 Gene3D G3DSA:1.20.1260.130 3 284 6.1E-105 T 01-11-2018 MLA2C4_16340 582c596de7888c5dfdcfe5cc9973ad73 284 SUPERFAMILY SSF47240 1 283 3.11E-90 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_16340 582c596de7888c5dfdcfe5cc9973ad73 284 Pfam PF05067 Manganese containing catalase 1 277 3.4E-68 T 01-11-2018 IPR007760 Manganese catalase MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 Pfam PF00005 ABC transporter 310 453 7.9E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 SUPERFAMILY SSF52540 6 233 5.33E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 SUPERFAMILY SSF52540 276 519 2.15E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 SMART SM00382 319 502 2.7E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 SMART SM00382 31 241 8.3E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 Gene3D G3DSA:3.40.50.300 277 526 2.0E-59 T 01-11-2018 MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 Pfam PF00005 ABC transporter 22 171 1.0E-26 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17330 9bb1728c9ae697d7afc8e5fa82e1dd98 551 Gene3D G3DSA:3.40.50.300 4 246 1.4E-65 T 01-11-2018 MLA2C4_15450 a0c2dd5ac7b87da98c5c2b976b44fe45 161 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_15450 a0c2dd5ac7b87da98c5c2b976b44fe45 161 SUPERFAMILY SSF55811 9 145 4.47E-27 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_15450 a0c2dd5ac7b87da98c5c2b976b44fe45 161 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.0E-4 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_15450 a0c2dd5ac7b87da98c5c2b976b44fe45 161 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.0E-4 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_15450 a0c2dd5ac7b87da98c5c2b976b44fe45 161 Gene3D G3DSA:3.90.79.10 13 158 2.6E-26 T 01-11-2018 MLA2C4_15450 a0c2dd5ac7b87da98c5c2b976b44fe45 161 Pfam PF00293 NUDIX domain 7 127 3.2E-17 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 2.1E-22 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 SMART SM00448 3 116 2.1E-37 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 Pfam PF00072 Response regulator receiver domain 6 116 3.1E-31 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 Gene3D G3DSA:3.40.50.12740 3 209 7.6E-75 T 01-11-2018 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 SUPERFAMILY SSF46894 143 209 4.76E-23 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 SMART SM00421 148 205 1.9E-26 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 SUPERFAMILY SSF52172 2 131 6.55E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.3E-16 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.3E-16 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_11320 f1ad3b519206dd9e7e700253d146c56c 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.3E-16 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_24980 ef9b1fe0a344196753e700c2b78decf2 272 SMART SM00894 230 266 2.3E-17 T 01-11-2018 IPR008613 Excalibur calcium-binding domain MLA2C4_24980 ef9b1fe0a344196753e700c2b78decf2 272 Pfam PF00395 S-layer homology domain 150 192 2.0E-8 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_24980 ef9b1fe0a344196753e700c2b78decf2 272 Pfam PF00395 S-layer homology domain 30 72 1.1E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_24980 ef9b1fe0a344196753e700c2b78decf2 272 Pfam PF00395 S-layer homology domain 90 134 2.3E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_24980 ef9b1fe0a344196753e700c2b78decf2 272 Pfam PF05901 Excalibur calcium-binding domain 231 266 7.9E-13 T 01-11-2018 IPR008613 Excalibur calcium-binding domain MLA2C4_06845 466ef48e5756af802cc5075a2d1306b3 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 267 1.1E-14 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_06845 466ef48e5756af802cc5075a2d1306b3 282 Gene3D G3DSA:1.10.3720.10 4 275 1.7E-55 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06845 466ef48e5756af802cc5075a2d1306b3 282 SUPERFAMILY SSF161098 3 270 9.35E-58 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_14055 d149fe28638223f024126a00004ade67 192 Gene3D G3DSA:2.60.120.10 46 190 1.5E-35 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_14055 d149fe28638223f024126a00004ade67 192 Pfam PF05995 Cysteine dioxygenase type I 44 171 3.9E-6 T 01-11-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 MLA2C4_14055 d149fe28638223f024126a00004ade67 192 SUPERFAMILY SSF51182 8 189 3.56E-34 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 PIRSF PIRSF004749 1 155 6.1E-48 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 Hamap MF_00163 Peptide deformylase [def]. 2 155 27.783 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 PRINTS PR01576 Peptide deformylase signature 119 148 3.4E-35 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 PRINTS PR01576 Peptide deformylase signature 100 118 3.4E-35 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 PRINTS PR01576 Peptide deformylase signature 88 99 3.4E-35 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 PRINTS PR01576 Peptide deformylase signature 33 62 3.4E-35 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 Gene3D G3DSA:3.90.45.10 1 156 8.3E-63 T 01-11-2018 IPR036821 Peptide deformylase superfamily MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 SUPERFAMILY SSF56420 1 148 3.27E-54 T 01-11-2018 IPR036821 Peptide deformylase superfamily MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 153 6.8E-53 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20210 265cec773c16a98211f63a2fdeeea257 156 Pfam PF01327 Polypeptide deformylase 4 148 3.8E-47 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_18370 05d1962c401bc514e1c5efedb4e03d39 281 Pfam PF00929 Exonuclease 23 174 4.9E-22 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_18370 05d1962c401bc514e1c5efedb4e03d39 281 SUPERFAMILY SSF53098 5 179 6.25E-28 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_18370 05d1962c401bc514e1c5efedb4e03d39 281 Gene3D G3DSA:3.30.420.10 2 230 1.2E-43 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_18370 05d1962c401bc514e1c5efedb4e03d39 281 SMART SM00479 6 183 2.4E-17 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_09545 18330296f008e6b7c68d9ea4e511fcbb 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 460 1.3E-78 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_09545 18330296f008e6b7c68d9ea4e511fcbb 542 Gene3D G3DSA:3.90.76.10 68 190 1.1E-175 T 01-11-2018 MLA2C4_09545 18330296f008e6b7c68d9ea4e511fcbb 542 Gene3D G3DSA:3.40.190.10 49 529 1.1E-175 T 01-11-2018 MLA2C4_09545 18330296f008e6b7c68d9ea4e511fcbb 542 SUPERFAMILY SSF53850 32 536 1.41E-128 T 01-11-2018 MLA2C4_09545 18330296f008e6b7c68d9ea4e511fcbb 542 PIRSF PIRSF002741 1 542 4.7E-112 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_09545 18330296f008e6b7c68d9ea4e511fcbb 542 Gene3D G3DSA:3.10.105.10 290 512 1.1E-175 T 01-11-2018 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 528 5.0E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 489 5.0E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 509 5.0E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 5.0E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 426 530 1.3E-13 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Gene3D G3DSA:3.30.565.10 376 526 2.5E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Gene3D G3DSA:3.30.450.20 200 312 1.1E-20 T 01-11-2018 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Gene3D G3DSA:3.30.450.20 31 165 9.6E-50 T 01-11-2018 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Pfam PF00989 PAS fold 217 284 1.5E-5 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 SMART SM00387 420 531 6.1E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 322 366 1.2E-8 T 01-11-2018 IPR039506 SpoOB, alpha-helical domain MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 Pfam PF17203 Single cache domain 3 38 168 4.8E-30 T 01-11-2018 IPR033463 Single cache domain 3 MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 SUPERFAMILY SSF55874 386 528 6.81E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 SUPERFAMILY SSF55785 208 309 6.09E-8 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 SUPERFAMILY SSF103190 37 167 5.49E-41 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_02995 ac9629c90e70a4253d5e37978a7a54fa 534 SUPERFAMILY SSF55890 323 408 1.83E-9 T 01-11-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 MLA2C4_12740 25d2d38848aeb643fd42e8bf3860e0a2 519 Gene3D G3DSA:2.60.40.10 420 519 1.3E-8 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_12740 25d2d38848aeb643fd42e8bf3860e0a2 519 Pfam PF02638 Glycosyl hydrolase-like 10 39 359 1.4E-108 T 01-11-2018 IPR003790 Glycosyl hydrolase-like 10 MLA2C4_12740 25d2d38848aeb643fd42e8bf3860e0a2 519 SUPERFAMILY SSF51445 66 327 2.15E-24 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_12740 25d2d38848aeb643fd42e8bf3860e0a2 519 Gene3D G3DSA:3.20.20.70 59 239 5.3E-6 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.024 T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 2.4E-103 T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 Gene3D G3DSA:3.90.230.10 1 248 4.3E-109 T 01-11-2018 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 SUPERFAMILY SSF55920 1 246 7.59E-93 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 Pfam PF00557 Metallopeptidase family M24 12 239 9.7E-58 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.5E-23 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 3.5E-23 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.5E-23 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_00785 39ace4112a1f09c2d5fdc48154a9bd60 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 3.5E-23 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_11610 1e764fd96bfa3e45c9d30c3af92ac8a4 72 Pfam PF09466 Hypothetical protein Yqai 1 69 4.1E-16 T 01-11-2018 IPR018474 Uncharacterised protein family YqaI MLA2C4_11610 1e764fd96bfa3e45c9d30c3af92ac8a4 72 Gene3D G3DSA:3.30.40.30 1 72 3.2E-28 T 01-11-2018 IPR023118 YqaI domain superfamily MLA2C4_11610 1e764fd96bfa3e45c9d30c3af92ac8a4 72 SUPERFAMILY SSF160713 1 69 5.89E-22 T 01-11-2018 IPR023118 YqaI domain superfamily MLA2C4_09815 f7c68e5d883d974fa1c50bda12fc1e90 257 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_09815 f7c68e5d883d974fa1c50bda12fc1e90 257 Pfam PF00005 ABC transporter 21 176 1.5E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09815 f7c68e5d883d974fa1c50bda12fc1e90 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 6.4E-9 T 01-11-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MLA2C4_09815 f7c68e5d883d974fa1c50bda12fc1e90 257 SUPERFAMILY SSF52540 3 246 8.54E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09815 f7c68e5d883d974fa1c50bda12fc1e90 257 Gene3D G3DSA:3.40.50.300 2 249 1.8E-58 T 01-11-2018 MLA2C4_09815 f7c68e5d883d974fa1c50bda12fc1e90 257 SMART SM00382 29 225 7.4E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23880 93f6a6cabd77c8d65cc4bd97f039961f 372 Pfam PF01594 AI-2E family transporter 12 354 1.5E-70 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like MLA2C4_23880 93f6a6cabd77c8d65cc4bd97f039961f 372 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 5.6E-126 T 01-11-2018 IPR014227 Putative transport protein YtvI-like MLA2C4_01080 7aedb55fc9a9d8c58ad7794c614a81e3 305 Gene3D G3DSA:1.10.3720.10 83 298 1.0E-16 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01080 7aedb55fc9a9d8c58ad7794c614a81e3 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 8.3E-41 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_01080 7aedb55fc9a9d8c58ad7794c614a81e3 305 SUPERFAMILY SSF161098 88 285 4.36E-16 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_05270 49959374e0895cb2936efd2b64a2a09c 302 Gene3D G3DSA:3.40.50.1820 7 299 4.8E-46 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05270 49959374e0895cb2936efd2b64a2a09c 302 Pfam PF00561 alpha/beta hydrolase fold 62 160 4.8E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_05270 49959374e0895cb2936efd2b64a2a09c 302 SUPERFAMILY SSF53474 42 297 2.16E-34 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 SMART SM00863 192 234 2.2E-8 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 Gene3D G3DSA:3.10.310.40 302 408 1.1E-11 T 01-11-2018 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 192 232 3.4E-7 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 Pfam PF01411 tRNA synthetases class II (A) 27 93 1.6E-7 T 01-11-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 SUPERFAMILY SSF55186 100 240 4.45E-34 T 01-11-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 SUPERFAMILY SSF50447 14 94 1.31E-16 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 Gene3D G3DSA:3.30.980.10 97 250 4.8E-41 T 01-11-2018 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 Gene3D G3DSA:2.40.30.130 12 96 5.5E-25 T 01-11-2018 MLA2C4_18845 3cf64437707b1013a56b202f8c1d028c 411 Pfam PF02272 DHHA1 domain 271 402 1.8E-11 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 Gene3D G3DSA:1.20.1530.20 3 396 1.3E-70 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 SUPERFAMILY SSF116726 538 608 5.62E-13 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 Pfam PF02254 TrkA-N domain 401 508 7.4E-9 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 Pfam PF02080 TrkA-C domain 542 608 2.0E-11 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 SUPERFAMILY SSF51735 396 539 1.47E-14 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 Gene3D G3DSA:3.30.70.1450 530 609 1.4E-18 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 Pfam PF00999 Sodium/hydrogen exchanger family 12 385 6.5E-74 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MLA2C4_03680 d68e506828022e0e36a55dfa025a27a6 609 Gene3D G3DSA:3.40.50.720 397 529 1.1E-15 T 01-11-2018 MLA2C4_19265 daad1927c575c87bd10e0701b5361524 231 Gene3D G3DSA:1.10.150.520 17 89 2.3E-41 T 01-11-2018 MLA2C4_19265 daad1927c575c87bd10e0701b5361524 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 3.2E-24 T 01-11-2018 MLA2C4_19265 daad1927c575c87bd10e0701b5361524 231 Gene3D G3DSA:3.40.50.1000 4 218 2.3E-41 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_19265 daad1927c575c87bd10e0701b5361524 231 SUPERFAMILY SSF56784 3 220 1.47E-31 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_19265 daad1927c575c87bd10e0701b5361524 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 183 1.8E-6 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 Gene3D G3DSA:1.20.1330.10 42 229 2.5E-40 T 01-11-2018 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 3.9E-37 T 01-11-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 Pfam PF00700 Bacterial flagellin C-terminal helical region 378 463 4.5E-23 T 01-11-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 Gene3D G3DSA:1.10.8.410 412 464 1.1E-18 T 01-11-2018 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 PRINTS PR00207 Flagellin signature 74 93 1.6E-18 T 01-11-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 PRINTS PR00207 Flagellin signature 35 52 1.6E-18 T 01-11-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 PRINTS PR00207 Flagellin signature 109 132 1.6E-18 T 01-11-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 Gene3D G3DSA:1.20.1330.10 363 409 3.5E-9 T 01-11-2018 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 SUPERFAMILY SSF64518 1 464 5.75E-93 T 01-11-2018 MLA2C4_08675 ee78592155ed5714a208c34bc4988997 464 Gene3D G3DSA:3.30.70.3070 238 362 3.5E-9 T 01-11-2018 MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 Pfam PF00072 Response regulator receiver domain 9 117 1.8E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 Gene3D G3DSA:1.10.10.10 132 236 4.5E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 Gene3D G3DSA:3.40.50.2300 4 131 9.7E-33 T 01-11-2018 MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 SUPERFAMILY SSF46894 136 232 5.95E-26 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 SMART SM00448 7 118 3.7E-38 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 4.9E-22 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 SUPERFAMILY SSF52172 3 126 2.28E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_09950 6834c31896cbb2b7ecf92dddb33c4468 237 SMART SM00862 155 231 2.8E-21 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_07455 182806d40cc04a0353a70129cb0a4c30 252 Pfam PF00977 Histidine biosynthesis protein 5 234 1.5E-90 T 01-11-2018 IPR006062 Histidine biosynthesis GO:0000105 MLA2C4_07455 182806d40cc04a0353a70129cb0a4c30 252 SUPERFAMILY SSF51366 1 251 2.83E-82 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_07455 182806d40cc04a0353a70129cb0a4c30 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 3.0E-114 T 01-11-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MLA2C4_07455 182806d40cc04a0353a70129cb0a4c30 252 Gene3D G3DSA:3.20.20.70 1 252 5.3E-108 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_07455 182806d40cc04a0353a70129cb0a4c30 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 49.028 T 01-11-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 SUPERFAMILY SSF55120 61 222 1.15E-41 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 SMART SM00363 1 57 1.8E-7 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 SUPERFAMILY SSF55174 1 54 3.53E-11 T 01-11-2018 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 218 4.6E-49 T 01-11-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 97 111 - T 01-11-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 Gene3D G3DSA:3.30.70.1560 127 200 5.9E-57 T 01-11-2018 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 Gene3D G3DSA:3.10.290.10 1 55 3.2E-17 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 Pfam PF01479 S4 domain 1 46 4.6E-6 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 Gene3D G3DSA:3.30.70.580 63 222 5.9E-57 T 01-11-2018 MLA2C4_23645 b107f536ce5b5f85bc85f74517c00c93 229 Pfam PF00849 RNA pseudouridylate synthase 62 185 3.9E-16 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06220 eb769846d14959ac835cf2e5323042cd 309 Gene3D G3DSA:1.10.3720.10 84 299 8.0E-19 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06220 eb769846d14959ac835cf2e5323042cd 309 SUPERFAMILY SSF161098 89 291 9.81E-16 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06220 eb769846d14959ac835cf2e5323042cd 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 7.2E-36 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_26120 15b73429d8c6d75f35ade83deda5ab73 414 Gene3D G3DSA:1.20.1250.20 222 406 6.1E-22 T 01-11-2018 MLA2C4_26120 15b73429d8c6d75f35ade83deda5ab73 414 Gene3D G3DSA:1.20.1250.20 27 221 2.2E-26 T 01-11-2018 MLA2C4_26120 15b73429d8c6d75f35ade83deda5ab73 414 Pfam PF07690 Major Facilitator Superfamily 32 364 5.7E-42 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_26120 15b73429d8c6d75f35ade83deda5ab73 414 SUPERFAMILY SSF103473 27 403 5.62E-61 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_23035 32091070944290646699ea4a711e6efe 350 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 3.8E-151 T 01-11-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MLA2C4_23035 32091070944290646699ea4a711e6efe 350 Gene3D G3DSA:3.40.1780.10 14 341 5.3E-137 T 01-11-2018 MLA2C4_23035 32091070944290646699ea4a711e6efe 350 Gene3D G3DSA:2.40.10.240 64 162 5.3E-137 T 01-11-2018 MLA2C4_23035 32091070944290646699ea4a711e6efe 350 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.477 T 01-11-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MLA2C4_23035 32091070944290646699ea4a711e6efe 350 Pfam PF02547 Queuosine biosynthesis protein 5 341 2.4E-143 T 01-11-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MLA2C4_23035 32091070944290646699ea4a711e6efe 350 SUPERFAMILY SSF111337 1 341 3.92E-141 T 01-11-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 Gene3D G3DSA:3.20.20.10 1 224 2.1E-71 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 PIRSF PIRSF004848 1 224 7.4E-65 T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 222 3.3E-50 T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 223 27.138 T 01-11-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 SUPERFAMILY SSF51419 2 222 5.09E-69 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_20385 1d4cf831235b450522cf4cd1886efc86 224 Pfam PF01168 Alanine racemase, N-terminal domain 12 222 4.3E-18 T 01-11-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_21295 1bab30a529e18b728c0c1d3615d38453 206 Gene3D G3DSA:2.60.480.10 1 97 8.9E-14 T 01-11-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily MLA2C4_21295 1bab30a529e18b728c0c1d3615d38453 206 Pfam PF12164 Stage V sporulation protein AA 2 88 1.6E-19 T 01-11-2018 IPR021997 Stage V sporulation protein AA MLA2C4_27635 adf4c826e1c41b7ab2a81a788e5e48df 174 SUPERFAMILY SSF53697 22 163 8.26E-5 T 01-11-2018 MLA2C4_27635 adf4c826e1c41b7ab2a81a788e5e48df 174 Gene3D G3DSA:3.40.50.10490 1 174 1.4E-59 T 01-11-2018 MLA2C4_27635 adf4c826e1c41b7ab2a81a788e5e48df 174 Pfam PF10740 Domain of unknown function (DUF2529) 1 171 1.7E-67 T 01-11-2018 IPR019676 Domain of unknown function (DUF2529) MLA2C4_07260 4690ec66d1cadcfeb92dd3ac9259f26a 391 Pfam PF04914 DltD protein 40 389 2.2E-122 T 01-11-2018 IPR006998 DltD MLA2C4_07260 4690ec66d1cadcfeb92dd3ac9259f26a 391 SUPERFAMILY SSF52266 270 389 2.56E-11 T 01-11-2018 MLA2C4_07260 4690ec66d1cadcfeb92dd3ac9259f26a 391 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 388 9.6E-131 T 01-11-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes MLA2C4_07260 4690ec66d1cadcfeb92dd3ac9259f26a 391 PIRSF PIRSF021438 1 391 2.1E-141 T 01-11-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 SUPERFAMILY SSF50249 554 659 4.16E-33 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 SUPERFAMILY SSF47323 363 573 9.32E-48 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 522 50.985 T 01-11-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 SUPERFAMILY SSF52374 5 360 5.9E-118 T 01-11-2018 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 530 660 7.1E-48 T 01-11-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Pfam PF01588 Putative tRNA binding domain 566 658 2.3E-27 T 01-11-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 523 3.8E-179 T 01-11-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 8.5E-34 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 361 372 8.5E-34 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 8.5E-34 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 8.5E-34 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 269 284 8.5E-34 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 PRINTS PR01041 Methionyl-tRNA synthetase signature 236 247 8.5E-34 T 01-11-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Gene3D G3DSA:3.40.50.620 8 344 3.3E-153 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Gene3D G3DSA:2.40.50.140 551 660 4.4E-36 T 01-11-2018 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Pfam PF09334 tRNA synthetases class I (M) 8 373 4.0E-120 T 01-11-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Gene3D G3DSA:1.10.730.10 351 521 8.7E-50 T 01-11-2018 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Gene3D G3DSA:2.170.220.10 119 238 3.3E-153 T 01-11-2018 MLA2C4_00225 9d43be4cbd095b8dd669dacfd68bdc20 660 Pfam PF08264 Anticodon-binding domain of tRNA 396 536 1.9E-8 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MLA2C4_22870 b1ca1294e59e736ea72ba71f538dd0a0 356 Gene3D G3DSA:1.10.8.1150 43 117 9.3E-24 T 01-11-2018 MLA2C4_22870 b1ca1294e59e736ea72ba71f538dd0a0 356 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 15 355 32.773 T 01-11-2018 IPR003770 Endolytic murein transglycosylase MLA2C4_22870 b1ca1294e59e736ea72ba71f538dd0a0 356 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 13 355 5.0E-99 T 01-11-2018 IPR003770 Endolytic murein transglycosylase MLA2C4_22870 b1ca1294e59e736ea72ba71f538dd0a0 356 Pfam PF02618 YceG-like family 49 349 8.5E-78 T 01-11-2018 IPR003770 Endolytic murein transglycosylase MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 299 43.266 T 01-11-2018 IPR033752 MetA family MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-146 T 01-11-2018 MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 Gene3D G3DSA:3.40.50.880 1 301 5.0E-130 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 PIRSF PIRSF000450 1 301 1.3E-146 T 01-11-2018 IPR033752 MetA family MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 2.0E-133 T 01-11-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 Pfam PF04204 Homoserine O-succinyltransferase 2 299 3.3E-141 T 01-11-2018 IPR033752 MetA family MLA2C4_28005 18f2b607c814b0ffa1b75f17b3fbb49c 301 SUPERFAMILY SSF52317 17 297 6.87E-104 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_27620 3cef8ee6f0c7878708ee206241d24e45 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.3E-170 T 01-11-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_27620 3cef8ee6f0c7878708ee206241d24e45 429 Gene3D G3DSA:3.65.10.10 21 229 1.8E-161 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MLA2C4_27620 3cef8ee6f0c7878708ee206241d24e45 429 SUPERFAMILY SSF55205 1 416 3.92E-134 T 01-11-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MLA2C4_27620 3cef8ee6f0c7878708ee206241d24e45 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 4.5E-92 T 01-11-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MLA2C4_27620 3cef8ee6f0c7878708ee206241d24e45 429 Gene3D G3DSA:3.65.10.10 6 413 1.8E-161 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MLA2C4_27620 3cef8ee6f0c7878708ee206241d24e45 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.501 T 01-11-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 Gene3D G3DSA:3.40.50.150 4 308 7.1E-107 T 01-11-2018 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.35 T 01-11-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 SUPERFAMILY SSF53335 4 309 1.95E-47 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 PIRSF PIRSF004486 1 310 5.9E-111 T 01-11-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 Pfam PF01795 MraW methylase family 2 310 2.3E-134 T 01-11-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 9.8E-130 T 01-11-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 Gene3D G3DSA:1.10.150.170 111 215 7.1E-107 T 01-11-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MLA2C4_20475 6eb887c46de452a067b6db9ffad3f273 310 SUPERFAMILY SSF81799 113 214 2.75E-36 T 01-11-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MLA2C4_27430 2ee1e55765aaa5fad2f35a6d200b58fd 172 SUPERFAMILY SSF56770 18 163 5.1E-67 T 01-11-2018 MLA2C4_27430 2ee1e55765aaa5fad2f35a6d200b58fd 172 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 20 161 7.4E-73 T 01-11-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27430 2ee1e55765aaa5fad2f35a6d200b58fd 172 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 10 160 43.172 T 01-11-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27430 2ee1e55765aaa5fad2f35a6d200b58fd 172 Gene3D G3DSA:3.40.50.12280 5 172 1.0E-77 T 01-11-2018 MLA2C4_27430 2ee1e55765aaa5fad2f35a6d200b58fd 172 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 3.4E-26 T 01-11-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 PRINTS PR01576 Peptide deformylase signature 121 139 5.8E-33 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 PRINTS PR01576 Peptide deformylase signature 47 76 5.8E-33 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 PRINTS PR01576 Peptide deformylase signature 140 169 5.8E-33 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 PRINTS PR01576 Peptide deformylase signature 108 119 5.8E-33 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 Gene3D G3DSA:3.90.45.10 1 184 8.9E-72 T 01-11-2018 IPR036821 Peptide deformylase superfamily MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 177 5.8E-51 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 Pfam PF01327 Polypeptide deformylase 4 171 9.2E-46 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 28.08 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 SUPERFAMILY SSF56420 2 178 1.83E-61 T 01-11-2018 IPR036821 Peptide deformylase superfamily MLA2C4_20770 573ca50b4a1cc6025d106f082ccfb703 184 PIRSF PIRSF004749 2 184 1.1E-47 T 01-11-2018 IPR023635 Peptide deformylase MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 01-11-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Gene3D G3DSA:3.40.50.300 967 1188 5.1E-54 T 01-11-2018 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Gene3D G3DSA:3.40.50.300 1 379 1.3E-54 T 01-11-2018 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Gene3D G3DSA:1.20.1060.20 495 680 9.2E-67 T 01-11-2018 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 SUPERFAMILY SSF52540 3 1164 2.16E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 638 8.1E-29 T 01-11-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 SUPERFAMILY SSF75553 484 687 1.31E-55 T 01-11-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 2.6E-65 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 SMART SM00968 519 638 8.9E-39 T 01-11-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Gene3D G3DSA:3.30.70.1620 579 667 9.2E-67 T 01-11-2018 MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 PIRSF PIRSF005719 1 1187 0.0 T 01-11-2018 IPR024704 Structural maintenance of chromosomes protein MLA2C4_20110 1c7623d92da4ed84285d4220e65f20b9 1189 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.308 T 01-11-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MLA2C4_26540 6431023162a045cb45bb8dea1a30c9ad 247 Pfam PF12146 Serine aminopeptidase, S33 17 229 5.4E-17 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_26540 6431023162a045cb45bb8dea1a30c9ad 247 PIRSF PIRSF017388 2 247 1.3E-94 T 01-11-2018 IPR012354 Esterase/lipase GO:0052689 MLA2C4_26540 6431023162a045cb45bb8dea1a30c9ad 247 Gene3D G3DSA:3.40.50.1820 1 247 4.7E-61 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_26540 6431023162a045cb45bb8dea1a30c9ad 247 SUPERFAMILY SSF53474 12 246 1.66E-35 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 SUPERFAMILY SSF46785 1 80 1.58E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 Gene3D G3DSA:3.40.190.10 93 286 5.8E-57 T 01-11-2018 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 Gene3D G3DSA:3.40.190.10 161 265 5.8E-57 T 01-11-2018 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-10 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-10 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-10 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 Pfam PF03466 LysR substrate binding domain 93 288 3.6E-37 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.7E-22 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 SUPERFAMILY SSF53850 91 290 1.15E-32 T 01-11-2018 MLA2C4_13825 3330cfb4e9dcc4528ff11d38fd4a3ff2 299 Gene3D G3DSA:1.10.10.10 1 83 3.7E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20700 1074832b9bfc242219f91cebaf0afe5f 276 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 24 238 3.0E-123 T 01-11-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 MLA2C4_20700 1074832b9bfc242219f91cebaf0afe5f 276 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 247 56.033 T 01-11-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 3.7E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 3.7E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 3.7E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 Pfam PF01047 MarR family 34 87 3.2E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 SUPERFAMILY SSF46785 5 138 4.75E-30 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 Gene3D G3DSA:1.10.10.10 1 138 2.5E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17245 f30aebc61071629daf06317e71621b2a 138 SMART SM00347 24 123 4.9E-22 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_15395 f8fbbe65e182c58811e32c31089d0994 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 1.3E-21 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_15395 f8fbbe65e182c58811e32c31089d0994 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 1.4E-25 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 SMART SM00448 5 115 5.1E-46 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 Gene3D G3DSA:1.10.10.10 136 237 2.6E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 9.1E-28 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 Gene3D G3DSA:3.40.50.2300 3 126 1.6E-40 T 01-11-2018 MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 Pfam PF00072 Response regulator receiver domain 7 115 2.3E-31 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 SMART SM00862 156 233 2.1E-28 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 SUPERFAMILY SSF52172 3 124 3.13E-42 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_07780 f417d896be3b7d954eb4e4a577461648 238 SUPERFAMILY SSF46894 133 234 1.91E-31 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_04940 91a6445b93f0d19205d68e16cff69103 796 Pfam PF13111 Protein of unknown function (DUF3962) 15 217 3.0E-53 T 01-11-2018 IPR025085 Domain of unknown function DUF3962 MLA2C4_04940 91a6445b93f0d19205d68e16cff69103 796 Pfam PF13032 Domain of unknown function (DUF3893) 648 769 6.4E-29 T 01-11-2018 IPR024996 Domain of unknown function DUF3893 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 Pfam PF12833 Helix-turn-helix domain 105 183 6.2E-21 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 SUPERFAMILY SSF57884 9 88 6.15E-31 T 01-11-2018 IPR035451 Ada-like domain superfamily MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 166 182 9.6E-6 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 151 166 9.6E-6 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 Gene3D G3DSA:1.10.10.60 133 189 3.1E-17 T 01-11-2018 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 Gene3D G3DSA:1.10.10.60 81 132 2.2E-17 T 01-11-2018 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 SMART SM00342 99 182 4.1E-28 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 SUPERFAMILY SSF46689 83 133 5.82E-11 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 PIRSF PIRSF000408 3 190 1.2E-84 T 01-11-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 178 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 Pfam PF02805 Metal binding domain of Ada 12 74 3.1E-30 T 01-11-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 SUPERFAMILY SSF46689 136 185 8.06E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_19535 04857f3f075810c87651d9a32db5a263 198 Gene3D G3DSA:3.40.10.10 2 76 3.6E-31 T 01-11-2018 IPR035451 Ada-like domain superfamily MLA2C4_22895 e99c285827b88795415cb5f1b2d281cb 114 Pfam PF14470 Bacterial PH domain 12 110 9.4E-13 T 01-11-2018 IPR039519 YokE-like, PH domain MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.6E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.6E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 8.6E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.6E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.6E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.6E-37 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 SUPERFAMILY SSF51735 2 250 1.36E-86 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 Gene3D G3DSA:3.40.50.720 1 254 1.5E-86 T 01-11-2018 MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.0E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-7 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20855 4040a3c4727d5808cc94136f8af5d6c9 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 7.1E-62 T 01-11-2018 MLA2C4_25220 3c55fdd765c1bd1b089d582067d0e695 367 Gene3D G3DSA:3.40.640.10 24 277 2.9E-48 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_25220 3c55fdd765c1bd1b089d582067d0e695 367 Pfam PF03841 L-seryl-tRNA selenium transferase 56 277 9.5E-13 T 01-11-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MLA2C4_25220 3c55fdd765c1bd1b089d582067d0e695 367 SUPERFAMILY SSF53383 10 362 3.21E-37 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_25220 3c55fdd765c1bd1b089d582067d0e695 367 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 6 364 2.9E-167 T 01-11-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 MLA2C4_14120 d245cb12a3fea3303c52fe7a9b0f350f 293 SUPERFAMILY SSF56112 51 286 1.71E-16 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_14120 d245cb12a3fea3303c52fe7a9b0f350f 293 Gene3D G3DSA:1.10.510.10 75 291 7.1E-13 T 01-11-2018 MLA2C4_14120 d245cb12a3fea3303c52fe7a9b0f350f 293 Pfam PF00069 Protein kinase domain 76 243 1.4E-6 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MLA2C4_10780 c5ef733e3325eb33a4c36237b910d28f 323 SMART SM00849 24 228 3.4E-22 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_10780 c5ef733e3325eb33a4c36237b910d28f 323 Gene3D G3DSA:3.60.15.10 8 271 1.1E-54 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_10780 c5ef733e3325eb33a4c36237b910d28f 323 SUPERFAMILY SSF56281 4 270 7.6E-47 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_10780 c5ef733e3325eb33a4c36237b910d28f 323 Pfam PF00753 Metallo-beta-lactamase superfamily 32 228 3.8E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 Gene3D G3DSA:3.40.50.300 254 511 3.8E-48 T 01-11-2018 MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 Pfam PF00005 ABC transporter 310 437 9.1E-24 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 SUPERFAMILY SSF52540 277 483 4.37E-41 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 SUPERFAMILY SSF52540 4 214 4.15E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 Gene3D G3DSA:3.40.50.300 83 229 1.2E-33 T 01-11-2018 MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 SMART SM00382 318 493 1.9E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 SMART SM00382 29 186 7.7E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 Pfam PF12848 ABC transporter 174 268 7.9E-10 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 Gene3D G3DSA:3.40.50.300 1 82 1.9E-15 T 01-11-2018 MLA2C4_13835 fefe43c95b0618950745defeb694988b 542 Pfam PF00005 ABC transporter 20 134 1.1E-20 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19235 2ee40aab574b5895877f10fa7336807d 157 Pfam PF13471 Transglutaminase-like superfamily 50 142 7.1E-19 T 01-11-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 SUPERFAMILY SSF51412 4 314 9.29E-94 T 01-11-2018 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.806 T 01-11-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 SMART SM01240 3 327 6.1E-119 T 01-11-2018 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 1.7E-205 T 01-11-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 01-11-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 Gene3D G3DSA:3.20.20.70 1 327 1.5E-111 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 9.5E-69 T 01-11-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 PIRSF PIRSF036500 1 326 7.2E-200 T 01-11-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 MLA2C4_28290 847af51eb6e490d5b639454c5ca20f79 327 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 204 224 - T 01-11-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 SUPERFAMILY SSF52440 1 113 3.09E-48 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 SUPERFAMILY SSF51246 331 440 1.88E-37 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 Gene3D G3DSA:3.30.470.130 1 445 1.5E-191 T 01-11-2018 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 3.4E-75 T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 01-11-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.5E-45 T 01-11-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 SUPERFAMILY SSF56059 83 353 3.89E-66 T 01-11-2018 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 SMART SM00878 336 439 4.9E-51 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_13465 dba85054675e23d55f2dc2d9b9e3637f 445 Pfam PF02785 Biotin carboxylase C-terminal domain 336 439 1.8E-34 T 01-11-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MLA2C4_21280 20ba25c08df640240a4a8df8b16bd19f 338 Gene3D G3DSA:3.40.47.40 1 338 6.2E-154 T 01-11-2018 IPR038369 Stage V sporulation AD superfamily MLA2C4_21280 20ba25c08df640240a4a8df8b16bd19f 338 PIRSF PIRSF011570 1 336 4.4E-163 T 01-11-2018 IPR010894 Stage V sporulation AD MLA2C4_21280 20ba25c08df640240a4a8df8b16bd19f 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 333 1.3E-160 T 01-11-2018 IPR010894 Stage V sporulation AD MLA2C4_21280 20ba25c08df640240a4a8df8b16bd19f 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 333 1.9E-155 T 01-11-2018 IPR010894 Stage V sporulation AD MLA2C4_21280 20ba25c08df640240a4a8df8b16bd19f 338 SUPERFAMILY SSF53901 57 286 1.46E-13 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 1 512 9.9E-125 T 01-11-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 SUPERFAMILY SSF48163 323 516 3.79E-18 T 01-11-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 29 38 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 Gene3D G3DSA:2.30.30.300 169 214 2.0E-99 T 01-11-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 1 517 28.929 T 01-11-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 SUPERFAMILY SSF52374 2 315 2.31E-59 T 01-11-2018 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 Gene3D G3DSA:1.10.10.350 424 516 1.6E-12 T 01-11-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 Pfam PF01921 tRNA synthetases class I (K) 1 355 5.8E-121 T 01-11-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 Gene3D G3DSA:1.10.10.860 272 319 1.4E-18 T 01-11-2018 MLA2C4_13795 012456b75eca1affd95a775653644f83 517 Gene3D G3DSA:3.40.50.620 3 271 2.0E-99 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_22710 6047575c79993f3451dca234dd343c16 200 Gene3D G3DSA:3.40.50.1240 1 199 5.2E-19 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_22710 6047575c79993f3451dca234dd343c16 200 SUPERFAMILY SSF53254 1 193 9.42E-19 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_22710 6047575c79993f3451dca234dd343c16 200 SMART SM00855 2 166 8.3E-6 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_22710 6047575c79993f3451dca234dd343c16 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 75 1.2E-8 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_25940 f6f0826ec5de2ca4aba10cebdcfa40a1 221 Gene3D G3DSA:1.10.3720.10 8 221 1.7E-45 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_25940 f6f0826ec5de2ca4aba10cebdcfa40a1 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 50 219 8.9E-23 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_25940 f6f0826ec5de2ca4aba10cebdcfa40a1 221 SUPERFAMILY SSF161098 10 212 1.96E-44 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01150 98c8c698e364df7e996cfc40b9b76dbf 224 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 220 6.0E-79 T 01-11-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MLA2C4_01150 98c8c698e364df7e996cfc40b9b76dbf 224 SUPERFAMILY SSF161098 6 217 1.19E-48 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01150 98c8c698e364df7e996cfc40b9b76dbf 224 Gene3D G3DSA:1.10.3720.10 1 223 3.1E-55 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01150 98c8c698e364df7e996cfc40b9b76dbf 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 222 2.0E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_25750 99f546a2c43b7ebe87adb9116f02f9e9 292 Pfam PF01909 Nucleotidyltransferase domain 52 105 2.5E-5 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MLA2C4_25750 99f546a2c43b7ebe87adb9116f02f9e9 292 SUPERFAMILY SSF81301 60 105 7.2E-7 T 01-11-2018 MLA2C4_25750 99f546a2c43b7ebe87adb9116f02f9e9 292 Gene3D G3DSA:3.30.460.10 31 136 1.3E-6 T 01-11-2018 MLA2C4_25750 99f546a2c43b7ebe87adb9116f02f9e9 292 Pfam PF13427 Domain of unknown function (DUF4111) 182 280 6.2E-7 T 01-11-2018 IPR025184 Domain of unknown function DUF4111 MLA2C4_15120 e3ac1b56739ae3e0ea74c15845396436 254 Gene3D G3DSA:3.40.50.150 38 233 1.8E-34 T 01-11-2018 MLA2C4_15120 e3ac1b56739ae3e0ea74c15845396436 254 SUPERFAMILY SSF53335 11 240 6.51E-32 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_15120 e3ac1b56739ae3e0ea74c15845396436 254 Pfam PF13649 Methyltransferase domain 41 136 5.2E-12 T 01-11-2018 MLA2C4_15120 e3ac1b56739ae3e0ea74c15845396436 254 Gene3D G3DSA:2.20.25.570 144 209 1.8E-34 T 01-11-2018 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 15.072 T 01-11-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 Pfam PF02609 Exonuclease VII small subunit 7 57 3.2E-20 T 01-11-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 PIRSF PIRSF006488 1 76 1.1E-19 T 01-11-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 SUPERFAMILY SSF116842 3 66 3.4E-21 T 01-11-2018 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 47 9.0E-20 T 01-11-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 Gene3D G3DSA:1.10.287.1040 1 75 7.4E-22 T 01-11-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 MLA2C4_21860 ef2c8d90885b437630c6543b6af4ceef 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 4.6E-22 T 01-11-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 Gene3D G3DSA:3.30.1240.10 80 181 4.0E-60 T 01-11-2018 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 252 2.8E-56 T 01-11-2018 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 01-11-2018 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 4.8E-48 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 225 1.6E-25 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 Gene3D G3DSA:3.40.50.1000 5 251 4.0E-60 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 ProSitePatterns PS01229 Hypothetical cof family signature 2. 206 228 - T 01-11-2018 MLA2C4_10555 6fd7d573449214be719a5725eca6111d 258 SUPERFAMILY SSF56784 2 256 2.58E-55 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 1.7E-127 T 01-11-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 41.908 T 01-11-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 SUPERFAMILY SSF51395 1 301 2.43E-88 T 01-11-2018 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 PIRSF PIRSF000164 1 303 8.7E-86 T 01-11-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Pfam PF01180 Dihydroorotate dehydrogenase 4 286 2.6E-96 T 01-11-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 01-11-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 01-11-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MLA2C4_20305 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Gene3D G3DSA:3.20.20.70 1 303 1.1E-100 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_06315 0e7e87d8f5529a323e91e1cc6ae95170 297 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 39 295 2.3E-77 T 01-11-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06315 0e7e87d8f5529a323e91e1cc6ae95170 297 Pfam PF00849 RNA pseudouridylate synthase 91 241 3.7E-31 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06315 0e7e87d8f5529a323e91e1cc6ae95170 297 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 01-11-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06315 0e7e87d8f5529a323e91e1cc6ae95170 297 Gene3D G3DSA:3.30.2350.10 83 297 2.0E-69 T 01-11-2018 MLA2C4_06315 0e7e87d8f5529a323e91e1cc6ae95170 297 SUPERFAMILY SSF55120 75 295 6.72E-73 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_26940 803ca60934f3730af729a0d210e15e6f 107 Gene3D G3DSA:1.20.58.280 1 106 1.5E-44 T 01-11-2018 MLA2C4_26940 803ca60934f3730af729a0d210e15e6f 107 SUPERFAMILY SSF46973 1 101 1.07E-37 T 01-11-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 MLA2C4_26940 803ca60934f3730af729a0d210e15e6f 107 PIRSF PIRSF000699 1 107 1.7E-41 T 01-11-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 MLA2C4_26940 803ca60934f3730af729a0d210e15e6f 107 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 100 3.5E-37 T 01-11-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 MLA2C4_11180 3b299a161ce46493240802810545ece5 427 Gene3D G3DSA:3.90.226.10 281 426 2.6E-11 T 01-11-2018 MLA2C4_11180 3b299a161ce46493240802810545ece5 427 Gene3D G3DSA:3.90.226.10 171 268 5.2E-8 T 01-11-2018 MLA2C4_11180 3b299a161ce46493240802810545ece5 427 Pfam PF03572 Peptidase family S41 183 402 1.4E-24 T 01-11-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MLA2C4_11180 3b299a161ce46493240802810545ece5 427 SUPERFAMILY SSF52096 101 421 1.66E-38 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_04910 b8b698336e9510c2c54b47f0d4681079 440 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_04910 b8b698336e9510c2c54b47f0d4681079 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 291 308 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_04910 b8b698336e9510c2c54b47f0d4681079 440 Pfam PF07690 Major Facilitator Superfamily 253 423 4.8E-12 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_04910 b8b698336e9510c2c54b47f0d4681079 440 Pfam PF00083 Sugar (and other) transporter 17 232 1.0E-27 T 01-11-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MLA2C4_04910 b8b698336e9510c2c54b47f0d4681079 440 Gene3D G3DSA:1.20.1250.20 13 431 2.3E-69 T 01-11-2018 MLA2C4_04910 b8b698336e9510c2c54b47f0d4681079 440 SUPERFAMILY SSF103473 13 420 4.19E-65 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 SMART SM00354 2 72 2.8E-29 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 Pfam PF13377 Periplasmic binding protein-like domain 175 336 1.8E-31 T 01-11-2018 MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 SUPERFAMILY SSF53822 61 338 1.93E-74 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 Gene3D G3DSA:3.40.50.2300 167 330 2.8E-92 T 01-11-2018 MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.7E-19 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 Gene3D G3DSA:1.10.260.40 1 60 6.0E-23 T 01-11-2018 MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 SUPERFAMILY SSF47413 2 60 1.48E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_20965 4d213cabc78b120ea1fe656435fb2161 343 Gene3D G3DSA:3.40.50.2300 76 328 2.8E-92 T 01-11-2018 MLA2C4_16130 926634ab30998f5ec28f395e1aa2124d 174 SUPERFAMILY SSF55811 5 116 4.87E-22 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_16130 926634ab30998f5ec28f395e1aa2124d 174 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_16130 926634ab30998f5ec28f395e1aa2124d 174 Pfam PF00293 NUDIX domain 7 109 1.5E-14 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_16130 926634ab30998f5ec28f395e1aa2124d 174 Gene3D G3DSA:3.90.79.10 2 159 3.3E-28 T 01-11-2018 MLA2C4_07125 05504bbfc30a7c8dee0d56221bf2dca0 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 71.9 T 01-11-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MLA2C4_07125 05504bbfc30a7c8dee0d56221bf2dca0 165 Gene3D G3DSA:3.30.1130.10 21 165 8.3E-69 T 01-11-2018 MLA2C4_07125 05504bbfc30a7c8dee0d56221bf2dca0 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 138 9.1E-57 T 01-11-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MLA2C4_07125 05504bbfc30a7c8dee0d56221bf2dca0 165 Pfam PF14489 QueF-like protein 62 140 1.2E-35 T 01-11-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MLA2C4_07125 05504bbfc30a7c8dee0d56221bf2dca0 165 SUPERFAMILY SSF55620 27 134 3.11E-28 T 01-11-2018 MLA2C4_07125 05504bbfc30a7c8dee0d56221bf2dca0 165 PIRSF PIRSF027377 8 147 1.0E-62 T 01-11-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MLA2C4_28410 0691c9408547b4a0ba64425c6c68b231 96 SUPERFAMILY SSF54995 1 95 1.57E-35 T 01-11-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28410 0691c9408547b4a0ba64425c6c68b231 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.4E-33 T 01-11-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28410 0691c9408547b4a0ba64425c6c68b231 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 24.045 T 01-11-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_28410 0691c9408547b4a0ba64425c6c68b231 96 Gene3D G3DSA:3.30.70.60 1 96 9.6E-37 T 01-11-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MLA2C4_28410 0691c9408547b4a0ba64425c6c68b231 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 01-11-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 MLA2C4_28410 0691c9408547b4a0ba64425c6c68b231 96 Pfam PF01250 Ribosomal protein S6 3 92 1.7E-30 T 01-11-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SUPERFAMILY SSF158911 730 860 1.02E-48 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Gene3D G3DSA:2.60.40.1850 553 681 1.2E-49 T 01-11-2018 MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SUPERFAMILY SSF158911 15 160 3.14E-49 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SMART SM00725 738 859 4.5E-43 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SMART SM00725 362 483 4.9E-43 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SMART SM00725 563 684 1.3E-45 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SMART SM00725 196 317 5.5E-31 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SMART SM00725 33 154 1.9E-44 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SUPERFAMILY SSF158911 185 323 1.83E-42 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SUPERFAMILY SSF158911 556 690 3.66E-48 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Pfam PF05031 Iron Transport-associated domain 32 147 1.0E-36 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Pfam PF05031 Iron Transport-associated domain 562 677 2.9E-37 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Pfam PF05031 Iron Transport-associated domain 361 476 1.2E-36 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Pfam PF05031 Iron Transport-associated domain 194 310 1.9E-32 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Pfam PF05031 Iron Transport-associated domain 737 853 1.3E-36 T 01-11-2018 IPR006635 NEAT domain MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 912 940 5.3E-13 T 01-11-2018 IPR017502 Sortase B cell surface sorting signal MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 SUPERFAMILY SSF158911 355 489 7.19E-47 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Gene3D G3DSA:2.60.40.1850 179 322 2.1E-43 T 01-11-2018 MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Gene3D G3DSA:2.60.40.1850 724 857 6.4E-50 T 01-11-2018 MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Gene3D G3DSA:2.60.40.1850 339 482 3.6E-49 T 01-11-2018 MLA2C4_23630 7cceb7100816e516fd29c3b28942421e 944 Gene3D G3DSA:2.60.40.1850 20 153 7.3E-48 T 01-11-2018 MLA2C4_05415 a0612192f5f0d1d6a1af3d184f6dd783 413 SUPERFAMILY SSF56300 5 300 6.79E-59 T 01-11-2018 MLA2C4_05415 a0612192f5f0d1d6a1af3d184f6dd783 413 Pfam PF00149 Calcineurin-like phosphoesterase 5 203 7.6E-17 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_05415 a0612192f5f0d1d6a1af3d184f6dd783 413 Gene3D G3DSA:3.60.21.10 2 255 7.5E-62 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_05415 a0612192f5f0d1d6a1af3d184f6dd783 413 PIRSF PIRSF033091 1 413 2.6E-162 T 01-11-2018 IPR014576 Predicted phosphoesterase, YhaO type MLA2C4_14715 15e7df403148647dc78525148b533f48 172 Gene3D G3DSA:3.30.460.10 6 172 1.2E-44 T 01-11-2018 MLA2C4_14715 15e7df403148647dc78525148b533f48 172 SUPERFAMILY SSF81301 10 168 2.42E-42 T 01-11-2018 MLA2C4_14715 15e7df403148647dc78525148b533f48 172 Pfam PF04229 GrpB protein 9 165 4.9E-41 T 01-11-2018 IPR007344 GrpB/Dephospho-CoA kinase MLA2C4_26945 60535391c0e6e2b0af52a07fcfc87c40 435 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 423 8.7E-137 T 01-11-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 MLA2C4_26945 60535391c0e6e2b0af52a07fcfc87c40 435 PIRSF PIRSF006351 1 432 2.2E-146 T 01-11-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_26945 60535391c0e6e2b0af52a07fcfc87c40 435 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 423 8.7E-137 T 01-11-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_26945 60535391c0e6e2b0af52a07fcfc87c40 435 Pfam PF02378 Phosphotransferase system, EIIC 29 349 1.3E-57 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 01-11-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 81 4.1E-30 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 SUPERFAMILY SSF55594 3 81 4.06E-28 T 01-11-2018 IPR035895 HPr-like superfamily MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.1E-21 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.1E-21 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.1E-21 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 Pfam PF00381 PTS HPr component phosphorylation site 3 82 6.6E-30 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_26650 ff14a40bccdb086a8051c164dc1f6892 82 Gene3D G3DSA:3.30.1340.10 1 82 2.0E-36 T 01-11-2018 IPR035895 HPr-like superfamily MLA2C4_15690 2981187c3a23c0b41d223a68e8029d3c 260 Pfam PF01791 DeoC/LacD family aldolase 19 227 7.4E-26 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_15690 2981187c3a23c0b41d223a68e8029d3c 260 SMART SM01133 18 228 2.9E-30 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_15690 2981187c3a23c0b41d223a68e8029d3c 260 SUPERFAMILY SSF51569 4 243 2.05E-61 T 01-11-2018 MLA2C4_15690 2981187c3a23c0b41d223a68e8029d3c 260 PIRSF PIRSF038992 1 257 2.6E-66 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_15690 2981187c3a23c0b41d223a68e8029d3c 260 Gene3D G3DSA:3.20.20.70 1 260 2.9E-78 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_07880 7a47ab6ae4905534ae4c48c95bdf16b5 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 217 9.1E-92 T 01-11-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MLA2C4_07880 7a47ab6ae4905534ae4c48c95bdf16b5 225 SUPERFAMILY SSF52540 5 220 1.91E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07880 7a47ab6ae4905534ae4c48c95bdf16b5 225 Pfam PF02224 Cytidylate kinase 7 219 1.0E-82 T 01-11-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MLA2C4_07880 7a47ab6ae4905534ae4c48c95bdf16b5 225 Gene3D G3DSA:3.40.50.300 1 221 8.0E-89 T 01-11-2018 MLA2C4_07880 7a47ab6ae4905534ae4c48c95bdf16b5 225 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.697 T 01-11-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MLA2C4_01155 0b8bc089c9172ac4424daabdb1ddac24 268 Gene3D G3DSA:3.40.190.10 122 227 1.0E-83 T 01-11-2018 MLA2C4_01155 0b8bc089c9172ac4424daabdb1ddac24 268 Pfam PF13531 Bacterial extracellular solute-binding protein 43 264 1.1E-48 T 01-11-2018 MLA2C4_01155 0b8bc089c9172ac4424daabdb1ddac24 268 SUPERFAMILY SSF53850 42 265 3.27E-67 T 01-11-2018 MLA2C4_01155 0b8bc089c9172ac4424daabdb1ddac24 268 Gene3D G3DSA:3.40.190.10 45 264 1.0E-83 T 01-11-2018 MLA2C4_01155 0b8bc089c9172ac4424daabdb1ddac24 268 PIRSF PIRSF004846 1 268 3.0E-90 T 01-11-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MLA2C4_01155 0b8bc089c9172ac4424daabdb1ddac24 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 48 263 6.4E-69 T 01-11-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 PIRSF PIRSF000149 1 334 1.9E-137 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 7.0E-69 T 01-11-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 8.9E-42 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 8.9E-42 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 8.9E-42 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 8.9E-42 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 8.9E-42 T 01-11-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 SUPERFAMILY SSF55347 151 313 4.46E-73 T 01-11-2018 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 01-11-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 7.8E-135 T 01-11-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 SUPERFAMILY SSF51735 3 167 8.85E-61 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 SMART SM00846 2 151 8.6E-86 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 101 4.7E-38 T 01-11-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 Gene3D G3DSA:3.30.360.10 150 314 2.0E-152 T 01-11-2018 MLA2C4_23810 dbfcde9dc6b8273667cc3697bc4f2082 342 Gene3D G3DSA:3.40.50.720 3 327 2.0E-152 T 01-11-2018 MLA2C4_03265 7515cab4a0a5bc714e68226c8305351e 396 Gene3D G3DSA:3.90.1150.10 38 387 2.0E-135 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_03265 7515cab4a0a5bc714e68226c8305351e 396 Pfam PF00155 Aminotransferase class I and II 43 384 2.6E-62 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_03265 7515cab4a0a5bc714e68226c8305351e 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 1.6E-191 T 01-11-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type MLA2C4_03265 7515cab4a0a5bc714e68226c8305351e 396 SUPERFAMILY SSF53383 8 394 1.5E-108 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_03265 7515cab4a0a5bc714e68226c8305351e 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 01-11-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MLA2C4_03265 7515cab4a0a5bc714e68226c8305351e 396 Gene3D G3DSA:3.40.640.10 58 294 2.0E-135 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 Gene3D G3DSA:3.30.160.660 412 551 9.0E-47 T 01-11-2018 MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 Gene3D G3DSA:1.10.490.140 274 605 9.0E-47 T 01-11-2018 MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 68 237 3.7E-43 T 01-11-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 266 649 6.3E-142 T 01-11-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 Gene3D G3DSA:3.40.50.720 25 189 5.3E-26 T 01-11-2018 MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 266 604 2.9E-88 T 01-11-2018 IPR003776 YcaO-like domain MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 Gene3D G3DSA:2.40.50.820 296 375 9.0E-47 T 01-11-2018 MLA2C4_06580 024cb69acc4c5b677b9b43a96cfb7453 649 SUPERFAMILY SSF69572 55 198 7.85E-7 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_21200 8aa9fd99b8db74708e4a039fde5cb65a 262 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 220 3.1E-21 T 01-11-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MLA2C4_21200 8aa9fd99b8db74708e4a039fde5cb65a 262 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 232 3.8E-72 T 01-11-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 MLA2C4_21200 8aa9fd99b8db74708e4a039fde5cb65a 262 Gene3D G3DSA:3.40.50.1360 1 232 1.2E-96 T 01-11-2018 MLA2C4_21200 8aa9fd99b8db74708e4a039fde5cb65a 262 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 234 39.836 T 01-11-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 MLA2C4_21200 8aa9fd99b8db74708e4a039fde5cb65a 262 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 113 131 - T 01-11-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 MLA2C4_21200 8aa9fd99b8db74708e4a039fde5cb65a 262 SUPERFAMILY SSF100950 1 232 5.12E-85 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_16605 95b8a0c2f40bd5108823c785674b1ff6 209 Pfam PF07081 Protein of unknown function (DUF1349) 22 201 5.0E-62 T 01-11-2018 IPR009784 Protein of unknown function DUF1349 MLA2C4_16605 95b8a0c2f40bd5108823c785674b1ff6 209 SUPERFAMILY SSF49899 5 201 5.94E-41 T 01-11-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MLA2C4_16605 95b8a0c2f40bd5108823c785674b1ff6 209 Gene3D G3DSA:2.60.120.200 17 207 5.8E-58 T 01-11-2018 MLA2C4_16605 95b8a0c2f40bd5108823c785674b1ff6 209 PIRSF PIRSF022704 10 208 1.9E-59 T 01-11-2018 IPR015987 Uncharacterised conserved protein UCP022704 MLA2C4_16450 39b089cbfb3face5f3d443ffb605e5a8 326 Pfam PF04960 Glutaminase 31 326 9.5E-108 T 01-11-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MLA2C4_16450 39b089cbfb3face5f3d443ffb605e5a8 326 Hamap MF_00313 Glutaminase [glsA]. 13 326 45.07 T 01-11-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MLA2C4_16450 39b089cbfb3face5f3d443ffb605e5a8 326 Gene3D G3DSA:1.10.1500.10 70 207 2.7E-123 T 01-11-2018 MLA2C4_16450 39b089cbfb3face5f3d443ffb605e5a8 326 SUPERFAMILY SSF56601 15 326 1.63E-119 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_16450 39b089cbfb3face5f3d443ffb605e5a8 326 TIGRFAM TIGR03814 Gln_ase: glutaminase A 17 326 7.5E-122 T 01-11-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MLA2C4_16450 39b089cbfb3face5f3d443ffb605e5a8 326 Gene3D G3DSA:3.40.710.10 44 326 2.7E-123 T 01-11-2018 MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 Gene3D G3DSA:1.20.120.420 3 147 2.7E-52 T 01-11-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 Gene3D G3DSA:3.40.50.10470 148 347 2.9E-66 T 01-11-2018 MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 33 335 2.0E-117 T 01-11-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 8 335 1.0E-137 T 01-11-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 SUPERFAMILY SSF100950 7 339 2.72E-122 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 4 346 39.303 T 01-11-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MLA2C4_02040 f4f25751643b8dc1c29b6d9a4d9b73a8 347 Pfam PF01008 Initiation factor 2 subunit family 46 335 7.5E-87 T 01-11-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MLA2C4_09330 3abb893b4af3234316f15b737ffefd30 327 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 235 324 8.1E-30 T 01-11-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_09330 3abb893b4af3234316f15b737ffefd30 327 SUPERFAMILY SSF53901 3 324 1.47E-60 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_09330 3abb893b4af3234316f15b737ffefd30 327 Gene3D G3DSA:3.40.47.10 2 327 1.3E-115 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_09330 3abb893b4af3234316f15b737ffefd30 327 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 324 63.772 T 01-11-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_09330 3abb893b4af3234316f15b737ffefd30 327 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 186 5.9E-30 T 01-11-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_09330 3abb893b4af3234316f15b737ffefd30 327 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 324 3.7E-109 T 01-11-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_12225 b306b39db2e8783f13bf9586d1f484e6 249 Gene3D G3DSA:3.90.470.20 33 233 2.4E-36 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_12225 b306b39db2e8783f13bf9586d1f484e6 249 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 121 206 3.2E-13 T 01-11-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_12225 b306b39db2e8783f13bf9586d1f484e6 249 Gene3D G3DSA:3.90.470.20 122 229 2.4E-36 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_12225 b306b39db2e8783f13bf9586d1f484e6 249 SUPERFAMILY SSF56214 121 234 2.79E-21 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_12225 b306b39db2e8783f13bf9586d1f484e6 249 SUPERFAMILY SSF56214 18 113 1.34E-16 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_01440 574e7f7a6114b939a5c362edadbe800e 154 Pfam PF17283 SprT-like zinc ribbon domain 114 150 2.3E-7 T 01-11-2018 IPR035240 SprT-like, zinc ribbon domain MLA2C4_01440 574e7f7a6114b939a5c362edadbe800e 154 SMART SM00731 6 150 1.1E-49 T 01-11-2018 IPR006640 SprT-like MLA2C4_01440 574e7f7a6114b939a5c362edadbe800e 154 Hamap MF_00745 Protein SprT-like. 6 150 40.882 T 01-11-2018 IPR023524 Uncharacterised protein family SprT-like MLA2C4_01440 574e7f7a6114b939a5c362edadbe800e 154 Pfam PF10263 SprT-like family 9 99 7.0E-12 T 01-11-2018 IPR006640 SprT-like MLA2C4_12230 8d432206961a1f519de7a2f4211ae13f 179 Gene3D G3DSA:3.40.1410.10 14 177 2.0E-23 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_12230 8d432206961a1f519de7a2f4211ae13f 179 SUPERFAMILY SSF64288 19 173 2.2E-27 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 01-11-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 229 6.9E-64 T 01-11-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 Gene3D G3DSA:3.20.20.70 1 237 1.5E-83 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 SMART SM00934 4 229 1.1E-91 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 228 1.1E-47 T 01-11-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 SUPERFAMILY SSF51366 4 233 5.24E-73 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_20300 8465d4885ba3b3c29909f2b9e827a9bc 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 39.82 T 01-11-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 SUPERFAMILY SSF53738 388 516 3.73E-6 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 Gene3D G3DSA:3.90.550.10 1 237 9.6E-72 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 Gene3D G3DSA:3.40.120.10 383 523 2.5E-15 T 01-11-2018 MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 297 1.2E-6 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 Gene3D G3DSA:2.160.10.10 238 379 3.3E-22 T 01-11-2018 MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 Pfam PF00483 Nucleotidyl transferase 2 230 1.2E-50 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 SUPERFAMILY SSF53448 1 278 9.1E-76 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 393 509 8.3E-10 T 01-11-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_22305 5796b7be633102c4a7d84fee2a07f668 784 SUPERFAMILY SSF51161 241 431 1.39E-27 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_11700 140182c1cc348f99b2620101a4175dfb 236 Pfam PF04542 Sigma-70 region 2 9 82 3.2E-9 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_11700 140182c1cc348f99b2620101a4175dfb 236 Gene3D G3DSA:1.20.140.160 88 226 2.1E-11 T 01-11-2018 MLA2C4_11700 140182c1cc348f99b2620101a4175dfb 236 SUPERFAMILY SSF88946 7 87 5.49E-17 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_11700 140182c1cc348f99b2620101a4175dfb 236 Gene3D G3DSA:1.20.120.1810 2 87 1.6E-13 T 01-11-2018 MLA2C4_11700 140182c1cc348f99b2620101a4175dfb 236 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 222 2.7E-21 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_11700 140182c1cc348f99b2620101a4175dfb 236 SUPERFAMILY SSF88659 147 223 5.23E-6 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 Gene3D G3DSA:3.40.50.720 1 166 2.2E-51 T 01-11-2018 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 5.8E-44 T 01-11-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 SMART SM01350 167 298 3.6E-6 T 01-11-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 1.8E-27 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 1.8E-27 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 16 1.8E-27 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 1.8E-27 T 01-11-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 298 4.4E-133 T 01-11-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 SUPERFAMILY SSF51735 1 153 9.86E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 SUPERFAMILY SSF48179 165 295 1.16E-40 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 276 9.7E-24 T 01-11-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MLA2C4_11365 9c7e3b8f630e3e8ddfb08b8b479aa851 298 Gene3D G3DSA:1.10.1040.10 167 297 4.1E-50 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SUPERFAMILY SSF50249 57 139 3.77E-17 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 TIGRFAM TIGR02063 RNase_R: ribonuclease R 11 712 7.6E-286 T 01-11-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 ProSitePatterns PS01175 Ribonuclease II family signature. 549 573 - T 01-11-2018 IPR022966 Ribonuclease II/R, conserved site MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SMART SM00357 75 137 4.1E-12 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SMART SM00357 139 206 0.086 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Gene3D G3DSA:2.40.50.140 633 740 1.7E-25 T 01-11-2018 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SUPERFAMILY SSF50249 630 710 1.96E-23 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Pfam PF00575 S1 RNA binding domain 629 711 1.1E-14 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SMART SM00316 630 712 3.8E-19 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 63 712 3.9E-249 T 01-11-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Hamap MF_01895 Ribonuclease R [rnr]. 27 712 60.866 T 01-11-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SUPERFAMILY SSF50249 130 229 2.71E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Gene3D G3DSA:2.40.50.140 139 207 1.1E-7 T 01-11-2018 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Gene3D G3DSA:2.40.50.140 61 138 6.4E-18 T 01-11-2018 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SUPERFAMILY SSF50249 212 629 3.77E-149 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Pfam PF08206 Ribonuclease B OB domain 151 205 4.7E-7 T 01-11-2018 IPR013223 Ribonuclease B, N-terminal OB domain MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Pfam PF08206 Ribonuclease B OB domain 76 136 3.5E-21 T 01-11-2018 IPR013223 Ribonuclease B, N-terminal OB domain MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 Pfam PF00773 RNB domain 252 580 3.3E-113 T 01-11-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MLA2C4_26535 6e3f8fd8cd5698915a8136524318b78d 812 SMART SM00955 252 582 8.6E-180 T 01-11-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 SUPERFAMILY SSF82708 148 204 3.4E-11 T 01-11-2018 IPR036867 R3H domain superfamily GO:0003676 MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 Pfam PF13083 KH domain 64 128 1.3E-14 T 01-11-2018 MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 Gene3D G3DSA:3.30.300.20 59 140 6.7E-24 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 Gene3D G3DSA:3.30.30.80 1 57 1.1E-18 T 01-11-2018 IPR038247 Jag, N-terminal domain superfamily MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 Gene3D G3DSA:3.30.1370.50 141 205 2.0E-25 T 01-11-2018 IPR036867 R3H domain superfamily GO:0003676 MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 SMART SM00393 126 205 1.2E-21 T 01-11-2018 IPR001374 R3H domain GO:0003676 MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 Pfam PF14804 Jag N-terminus 7 55 8.9E-20 T 01-11-2018 IPR032782 Jag, N-terminal MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 Pfam PF01424 R3H domain 145 203 3.6E-16 T 01-11-2018 IPR001374 R3H domain GO:0003676 MLA2C4_28465 d58682e894d419ff76bd840f82a344d8 205 SMART SM01245 5 57 6.2E-23 T 01-11-2018 IPR032782 Jag, N-terminal MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 Gene3D G3DSA:3.90.1150.10 258 391 2.8E-46 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 4 385 1.0E-168 T 01-11-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 SUPERFAMILY SSF53383 26 386 9.28E-119 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 Gene3D G3DSA:3.40.640.10 1 257 1.6E-95 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 PIRSF PIRSF001434 1 387 4.2E-144 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_24180 0b99048f0b406f9fa7d19ed8a5fcf2d9 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 384 2.3E-142 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_04260 f99f1e6d3da3e48c960629bec7ee412b 194 Pfam PF11579 Protein of unknown function (DUF3238) 1 193 6.4E-117 T 01-11-2018 IPR021631 Protein of unknown function DUF3238 MLA2C4_03070 993883c06406dac91978a74838f5fd04 235 Gene3D G3DSA:3.40.50.2300 1 138 3.5E-33 T 01-11-2018 MLA2C4_03070 993883c06406dac91978a74838f5fd04 235 Pfam PF00072 Response regulator receiver domain 4 115 7.3E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03070 993883c06406dac91978a74838f5fd04 235 PIRSF PIRSF006171 1 229 1.4E-82 T 01-11-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 MLA2C4_03070 993883c06406dac91978a74838f5fd04 235 SUPERFAMILY SSF52172 1 140 8.97E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_03070 993883c06406dac91978a74838f5fd04 235 SMART SM00448 2 115 9.3E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_04285 4a71ae2922685d0918230775e42f2afd 76 Pfam PF01206 Sulfurtransferase TusA 7 75 9.2E-25 T 01-11-2018 IPR001455 TusA-like domain MLA2C4_04285 4a71ae2922685d0918230775e42f2afd 76 SUPERFAMILY SSF64307 5 75 7.85E-26 T 01-11-2018 IPR036868 TusA-like domain superfamily MLA2C4_04285 4a71ae2922685d0918230775e42f2afd 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 01-11-2018 IPR001455 TusA-like domain MLA2C4_04285 4a71ae2922685d0918230775e42f2afd 76 Gene3D G3DSA:3.30.110.40 1 76 9.9E-30 T 01-11-2018 IPR036868 TusA-like domain superfamily MLA2C4_13520 b4e57e8033be5a5d050d4ccaafd85606 338 SUPERFAMILY SSF56601 4 284 1.82E-52 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13520 b4e57e8033be5a5d050d4ccaafd85606 338 Gene3D G3DSA:3.40.710.10 27 284 1.8E-65 T 01-11-2018 MLA2C4_13520 b4e57e8033be5a5d050d4ccaafd85606 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 114 131 1.9E-9 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_13520 b4e57e8033be5a5d050d4ccaafd85606 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 154 1.9E-9 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_13520 b4e57e8033be5a5d050d4ccaafd85606 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 1.9E-9 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_13520 b4e57e8033be5a5d050d4ccaafd85606 338 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 266 1.6E-53 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_09925 ada29713f52e27962d473d6f9ebc73c3 254 Pfam PF00561 alpha/beta hydrolase fold 11 238 1.1E-14 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_09925 ada29713f52e27962d473d6f9ebc73c3 254 SUPERFAMILY SSF53474 8 250 8.43E-38 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09925 ada29713f52e27962d473d6f9ebc73c3 254 Gene3D G3DSA:3.40.50.1820 1 251 1.3E-36 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_28080 d3788848f6ea3c3ef9f4f56e9a649948 246 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 4 246 63.414 T 01-11-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 MLA2C4_28080 d3788848f6ea3c3ef9f4f56e9a649948 246 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 62 236 3.8E-56 T 01-11-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 MLA2C4_28080 d3788848f6ea3c3ef9f4f56e9a649948 246 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 64 231 2.7E-61 T 01-11-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 MLA2C4_18475 6781c1219079f1db6640501584bc9305 313 TIGRFAM TIGR00688 rarD: protein RarD 9 266 1.3E-80 T 01-11-2018 IPR004626 RarD protein GO:0005887 MLA2C4_18475 6781c1219079f1db6640501584bc9305 313 SUPERFAMILY SSF103481 214 292 6.28E-7 T 01-11-2018 MLA2C4_18475 6781c1219079f1db6640501584bc9305 313 Pfam PF00892 EamA-like transporter family 10 150 3.7E-15 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_18475 6781c1219079f1db6640501584bc9305 313 SUPERFAMILY SSF103481 46 151 3.53E-11 T 01-11-2018 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.002 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 2.5E-72 T 01-11-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.9E-84 T 01-11-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.3E-42 T 01-11-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 01-11-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 Gene3D G3DSA:3.40.50.10860 8 276 6.5E-115 T 01-11-2018 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 SUPERFAMILY SSF51735 122 279 2.91E-55 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 SUPERFAMILY SSF53223 1 121 1.06E-40 T 01-11-2018 MLA2C4_21870 5125fa2755823483ce039aba5e1ad23a 286 Gene3D G3DSA:3.40.50.720 6 258 6.5E-115 T 01-11-2018 MLA2C4_00400 73a5c9e19008c53d512ce100448562e5 285 Gene3D G3DSA:3.30.470.10 1 124 3.7E-37 T 01-11-2018 MLA2C4_00400 73a5c9e19008c53d512ce100448562e5 285 Gene3D G3DSA:3.20.10.10 125 276 2.1E-45 T 01-11-2018 MLA2C4_00400 73a5c9e19008c53d512ce100448562e5 285 SUPERFAMILY SSF56752 1 272 7.46E-75 T 01-11-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MLA2C4_00400 73a5c9e19008c53d512ce100448562e5 285 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 01-11-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MLA2C4_00400 73a5c9e19008c53d512ce100448562e5 285 Pfam PF01063 Amino-transferase class IV 29 250 1.6E-54 T 01-11-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MLA2C4_07705 2199db3ca00f623493a9d4f1a49f1758 176 Gene3D G3DSA:1.10.443.10 5 176 3.1E-27 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_07705 2199db3ca00f623493a9d4f1a49f1758 176 Pfam PF00589 Phage integrase family 11 173 1.7E-22 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_07705 2199db3ca00f623493a9d4f1a49f1758 176 SUPERFAMILY SSF56349 8 175 7.95E-34 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_18035 6be9af45088ef7ce8ca0232e8f645a17 75 Pfam PF01166 TSC-22/dip/bun family 9 42 1.6E-6 T 01-11-2018 IPR000580 TSC-22 / Dip / Bun GO:0003700|GO:0006355 MLA2C4_18035 6be9af45088ef7ce8ca0232e8f645a17 75 SUPERFAMILY SSF58026 9 40 3.79E-5 T 01-11-2018 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 SUPERFAMILY SSF81296 41 209 4.48E-57 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 SUPERFAMILY SSF49265 219 403 1.57E-28 T 01-11-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 Gene3D G3DSA:2.10.10.20 408 455 1.2E-5 T 01-11-2018 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 SUPERFAMILY SSF51055 407 434 2.49E-5 T 01-11-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 Gene3D G3DSA:2.70.50.50 41 210 2.7E-66 T 01-11-2018 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 SMART SM00060 314 391 1.8E-7 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 SMART SM00060 220 293 1.1E-6 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 Gene3D G3DSA:2.60.40.10 218 304 1.3E-23 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 Gene3D G3DSA:2.60.40.10 312 402 5.4E-21 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 207 9.8E-39 T 01-11-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 SMART SM00495 409 455 0.001 T 01-11-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 MLA2C4_14795 b954df19ce04bd972a240d485ad8aa53 455 Pfam PF00041 Fibronectin type III domain 316 391 5.2E-9 T 01-11-2018 IPR003961 Fibronectin type III GO:0005515 MLA2C4_20760 eefe5e1f325049488f151981e9bf0e75 371 Gene3D G3DSA:3.40.50.970 5 371 2.6E-122 T 01-11-2018 MLA2C4_20760 eefe5e1f325049488f151981e9bf0e75 371 Pfam PF00676 Dehydrogenase E1 component 53 343 1.2E-102 T 01-11-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MLA2C4_20760 eefe5e1f325049488f151981e9bf0e75 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 364 2.6E-141 T 01-11-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MLA2C4_20760 eefe5e1f325049488f151981e9bf0e75 371 SUPERFAMILY SSF52518 18 366 3.54E-101 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_12145 03234256b35b5e72a20a24a1c737de49 351 SUPERFAMILY SSF52096 3 332 6.15E-59 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_12145 03234256b35b5e72a20a24a1c737de49 351 Pfam PF16113 Enoyl-CoA hydratase/isomerase 15 346 2.4E-118 T 01-11-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 MLA2C4_12145 03234256b35b5e72a20a24a1c737de49 351 Gene3D G3DSA:3.90.226.10 3 351 4.2E-115 T 01-11-2018 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 PRINTS PR00072 Malic enzyme signature 190 206 7.4E-9 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 PRINTS PR00072 Malic enzyme signature 80 102 7.4E-9 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 PRINTS PR00072 Malic enzyme signature 159 175 7.4E-9 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 01-11-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 SUPERFAMILY SSF53223 10 161 4.17E-55 T 01-11-2018 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 PIRSF PIRSF000106 20 398 1.9E-80 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 Gene3D G3DSA:3.40.50.720 161 398 9.2E-82 T 01-11-2018 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 SMART SM01274 18 151 3.1E-81 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 Pfam PF03949 Malic enzyme, NAD binding domain 165 385 3.0E-25 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 Pfam PF00390 Malic enzyme, N-terminal domain 20 151 1.6E-28 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 SUPERFAMILY SSF51735 163 393 6.25E-77 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 SMART SM00919 163 386 2.2E-123 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MLA2C4_03080 64ddb162ce00e13b1fda5e278b721d9e 399 Gene3D G3DSA:3.40.50.10380 1 160 7.5E-74 T 01-11-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 267 9.9E-89 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 Gene3D G3DSA:1.10.12.10 210 260 4.3E-29 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.811 T 01-11-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 1.7E-132 T 01-11-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 SUPERFAMILY SSF52096 7 267 1.99E-79 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_25260 4eacc364d2613f2c570cfac0cdbce44d 272 Gene3D G3DSA:3.90.226.10 1 209 9.5E-79 T 01-11-2018 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 SUPERFAMILY SSF46785 4 85 5.04E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 34 52 - T 01-11-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 Gene3D G3DSA:1.10.10.10 2 90 1.1E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 2.1E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.1E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 2.1E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.1E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 5.4E-18 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_27880 042751b96c302498b2f9c7b15cdb51b6 101 SMART SM00418 10 89 3.1E-30 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_17470 40ec8f69f5fb0e0094aabb76c90e8823 241 Gene3D G3DSA:3.40.50.300 1 239 2.3E-62 T 01-11-2018 MLA2C4_17470 40ec8f69f5fb0e0094aabb76c90e8823 241 SMART SM00382 27 211 3.4E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17470 40ec8f69f5fb0e0094aabb76c90e8823 241 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17470 40ec8f69f5fb0e0094aabb76c90e8823 241 Pfam PF00005 ABC transporter 19 161 2.1E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17470 40ec8f69f5fb0e0094aabb76c90e8823 241 SUPERFAMILY SSF52540 1 225 1.47E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28085 936a01700ce305a9d1a654e8e7459875 366 Gene3D G3DSA:3.40.50.2000 13 355 5.0E-68 T 01-11-2018 MLA2C4_28085 936a01700ce305a9d1a654e8e7459875 366 SUPERFAMILY SSF53756 13 364 6.81E-75 T 01-11-2018 MLA2C4_28085 936a01700ce305a9d1a654e8e7459875 366 Pfam PF13439 Glycosyltransferase Family 4 13 168 4.8E-19 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MLA2C4_28085 936a01700ce305a9d1a654e8e7459875 366 Gene3D G3DSA:3.40.50.2000 167 347 5.0E-68 T 01-11-2018 MLA2C4_28085 936a01700ce305a9d1a654e8e7459875 366 Pfam PF00534 Glycosyl transferases group 1 179 327 8.4E-31 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 SMART SM00926 261 315 6.8E-17 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Gene3D G3DSA:2.40.40.20 817 943 4.0E-27 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 SUPERFAMILY SSF50692 797 935 3.39E-33 T 01-11-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 SUPERFAMILY SSF54292 6 128 3.87E-29 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Gene3D G3DSA:3.10.20.740 5 127 7.5E-28 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Gene3D G3DSA:3.30.70.20 130 212 1.4E-19 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 2.1E-249 T 01-11-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Gene3D G3DSA:2.20.25.90 261 316 1.8E-18 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 78 1.7E-11 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 SUPERFAMILY SSF54862 136 219 1.76E-16 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Pfam PF00384 Molybdopterin oxidoreductase 318 741 4.6E-82 T 01-11-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Pfam PF12838 4Fe-4S dicluster domain 150 208 2.8E-6 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 266 283 - T 01-11-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Gene3D G3DSA:3.40.228.10 396 595 1.2E-161 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Gene3D G3DSA:3.40.50.740 323 782 1.2E-161 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 SUPERFAMILY SSF53706 255 775 1.57E-192 T 01-11-2018 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 263 315 2.0E-17 T 01-11-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 1.1E-10 T 01-11-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 SMART SM00929 85 126 4.5E-13 T 01-11-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 8.5E-20 T 01-11-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MLA2C4_03125 047f180fe587771913d108b67efbac1c 978 PIRSF PIRSF036643 1 968 0.0 T 01-11-2018 MLA2C4_21210 58e16d55a921595cd6e00e8c2110f4a7 300 SUPERFAMILY SSF56281 45 290 7.21E-47 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21210 58e16d55a921595cd6e00e8c2110f4a7 300 SMART SM00849 56 249 7.6E-5 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_21210 58e16d55a921595cd6e00e8c2110f4a7 300 Gene3D G3DSA:3.60.15.10 45 290 8.5E-68 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21210 58e16d55a921595cd6e00e8c2110f4a7 300 Pfam PF00753 Metallo-beta-lactamase superfamily 54 247 7.1E-12 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 214 230 - T 01-11-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 283 6.1E-97 T 01-11-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 Gene3D G3DSA:3.20.20.150 1 298 1.7E-102 T 01-11-2018 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 176 183 - T 01-11-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 01-11-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 286 40.735 T 01-11-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 Pfam PF01261 Xylose isomerase-like TIM barrel 22 238 8.6E-35 T 01-11-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 SMART SM00518 3 286 9.8E-121 T 01-11-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MLA2C4_22395 bc569d5cb016129d219f06a96fc6bdd1 298 SUPERFAMILY SSF51658 2 295 1.44E-99 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily MLA2C4_27295 e5a7619db4bfd0920a2deb5a8539f308 293 Gene3D G3DSA:3.90.550.10 1 292 8.8E-97 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_27295 e5a7619db4bfd0920a2deb5a8539f308 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 1.4E-121 T 01-11-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MLA2C4_27295 e5a7619db4bfd0920a2deb5a8539f308 293 SUPERFAMILY SSF53448 3 267 1.98E-70 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_27295 e5a7619db4bfd0920a2deb5a8539f308 293 Pfam PF00483 Nucleotidyl transferase 6 260 1.9E-35 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_12100 29f2d226ae5e9df964f166687b48fac3 381 Gene3D G3DSA:1.20.1250.20 4 369 3.4E-58 T 01-11-2018 MLA2C4_12100 29f2d226ae5e9df964f166687b48fac3 381 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_12100 29f2d226ae5e9df964f166687b48fac3 381 SUPERFAMILY SSF103473 7 377 1.83E-64 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_12100 29f2d226ae5e9df964f166687b48fac3 381 Pfam PF07690 Major Facilitator Superfamily 13 259 4.0E-37 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 Pfam PF01235 Sodium:alanine symporter family 52 448 8.4E-156 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 PRINTS PR00175 Sodium/alanine symporter signature 181 199 3.8E-51 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 PRINTS PR00175 Sodium/alanine symporter signature 345 367 3.8E-51 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 PRINTS PR00175 Sodium/alanine symporter signature 405 425 3.8E-51 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 PRINTS PR00175 Sodium/alanine symporter signature 91 113 3.8E-51 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 PRINTS PR00175 Sodium/alanine symporter signature 209 228 3.8E-51 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 PRINTS PR00175 Sodium/alanine symporter signature 300 318 3.8E-51 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_16460 107e607b51b3b3709100ca2e0368b318 474 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 436 2.0E-149 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_24270 fac6169d99b05956ddc4b20dc5ab32e7 118 Pfam PF12796 Ankyrin repeats (3 copies) 15 94 2.3E-11 T 01-11-2018 IPR020683 Ankyrin repeat-containing domain MLA2C4_24270 fac6169d99b05956ddc4b20dc5ab32e7 118 SUPERFAMILY SSF48403 22 118 2.8E-25 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_24270 fac6169d99b05956ddc4b20dc5ab32e7 118 SMART SM00248 30 59 36.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_24270 fac6169d99b05956ddc4b20dc5ab32e7 118 SMART SM00248 63 92 1.3E-5 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_24270 fac6169d99b05956ddc4b20dc5ab32e7 118 Gene3D G3DSA:1.25.40.20 12 118 2.5E-27 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 PIRSF PIRSF000460 3 801 7.5E-234 T 01-11-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 795 0.0 T 01-11-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 639 651 - T 01-11-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 SUPERFAMILY SSF53756 4 795 2.51E-301 T 01-11-2018 MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 Gene3D G3DSA:3.40.50.2000 461 788 0.0 T 01-11-2018 MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 Gene3D G3DSA:3.40.50.2000 15 795 0.0 T 01-11-2018 MLA2C4_25305 f19d4111ca32e30949fb1120d953611e 802 Pfam PF00343 Carbohydrate phosphorylase 93 795 0.0 T 01-11-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 SUPERFAMILY SSF54686 1 136 4.19E-58 T 01-11-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.6E-52 T 01-11-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.071 T 01-11-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.0E-62 T 01-11-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.6E-41 T 01-11-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.6E-41 T 01-11-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.6E-41 T 01-11-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.6E-41 T 01-11-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 01-11-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 01-11-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00710 86cccad083713518b98e2e0e0d699096 144 Gene3D G3DSA:3.90.1170.10 1 144 3.0E-55 T 01-11-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 Pfam PF01235 Sodium:alanine symporter family 49 459 1.0E-152 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 PRINTS PR00175 Sodium/alanine symporter signature 295 313 3.4E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 PRINTS PR00175 Sodium/alanine symporter signature 176 194 3.4E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 PRINTS PR00175 Sodium/alanine symporter signature 353 375 3.4E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 PRINTS PR00175 Sodium/alanine symporter signature 86 108 3.4E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 PRINTS PR00175 Sodium/alanine symporter signature 416 436 3.4E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 PRINTS PR00175 Sodium/alanine symporter signature 204 223 3.4E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_14970 8931c9384565149dcb8edc3d262febd2 496 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 447 1.3E-142 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 Pfam PF00318 Ribosomal protein S2 9 224 3.9E-102 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 01-11-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.0E-40 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.0E-40 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.0E-40 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.0E-40 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.0E-40 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.0E-40 T 01-11-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 Gene3D G3DSA:3.40.50.10490 10 215 1.3E-95 T 01-11-2018 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 SUPERFAMILY SSF52313 6 227 3.66E-100 T 01-11-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.8E-113 T 01-11-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 43.783 T 01-11-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 Gene3D G3DSA:1.10.287.610 97 152 1.3E-95 T 01-11-2018 MLA2C4_20005 3da42f77a941a2e1b2ff08736aec3b60 233 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 01-11-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 Gene3D G3DSA:3.40.50.1390 1 133 8.2E-28 T 01-11-2018 MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 SUPERFAMILY SSF53041 2 154 8.5E-27 T 01-11-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 Pfam PF07508 Recombinase 175 276 2.1E-23 T 01-11-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 SMART SM00857 3 154 5.3E-37 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 Pfam PF13408 Recombinase zinc beta ribbon domain 293 358 7.1E-8 T 01-11-2018 IPR025827 Recombinase zinc beta ribbon domain MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 Gene3D G3DSA:1.10.10.2600 142 281 1.0E-20 T 01-11-2018 IPR038109 DNA-binding recombinase domain superfamily MLA2C4_13175 89a99d084139f17b9e37500563c3831c 487 Pfam PF00239 Resolvase, N terminal domain 4 154 1.5E-27 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_15515 f3a300635ce8c4899525c6c652620be7 225 Pfam PF08713 DNA alkylation repair enzyme 6 189 1.2E-24 T 01-11-2018 IPR014825 DNA alkylation repair enzyme MLA2C4_15515 f3a300635ce8c4899525c6c652620be7 225 SUPERFAMILY SSF48371 1 222 3.45E-64 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_15515 f3a300635ce8c4899525c6c652620be7 225 Gene3D G3DSA:1.25.10.90 1 163 3.4E-6 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 SMART SM00155 138 165 5.8E-4 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 SMART SM00155 310 337 1.6E-5 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 PIRSF PIRSF000850 26 199 0.51 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 PIRSF PIRSF000850 228 308 1.3E-5 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 PIRSF PIRSF000850 297 372 4.6 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 23 395 4.6E-103 T 01-11-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 SUPERFAMILY SSF56024 190 377 2.18E-42 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 SUPERFAMILY SSF56024 24 228 9.64E-49 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 Gene3D G3DSA:3.30.870.10 38 224 5.5E-43 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 Gene3D G3DSA:3.30.870.10 225 370 2.3E-27 T 01-11-2018 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 Pfam PF13091 PLD-like domain 238 364 1.7E-28 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_27680 9f936f3454763d32c1248fb7af4e2ebf 397 Pfam PF13091 PLD-like domain 57 198 6.6E-16 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_12665 a99158222f626757d64258fcd21297ce 158 Pfam PF06695 Putative small multi-drug export protein 30 143 4.6E-13 T 01-11-2018 IPR009577 Putative small multi-drug export MLA2C4_23305 a1691850268106caab952576e31ba35c 556 SUPERFAMILY SSF52540 55 328 2.96E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23305 a1691850268106caab952576e31ba35c 556 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 266 3.9E-19 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 SUPERFAMILY SSF54211 351 532 2.12E-40 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_23305 a1691850268106caab952576e31ba35c 556 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 532 2.6E-280 T 01-11-2018 IPR014251 Sporulation protease LonB MLA2C4_23305 a1691850268106caab952576e31ba35c 556 Gene3D G3DSA:3.30.230.10 348 550 5.4E-49 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_23305 a1691850268106caab952576e31ba35c 556 Gene3D G3DSA:3.40.50.300 52 263 6.3E-31 T 01-11-2018 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 01-11-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 SMART SM00382 89 267 1.5E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23305 a1691850268106caab952576e31ba35c 556 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 350 533 2.6E-32 T 01-11-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 173 188 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 3.0E-32 T 01-11-2018 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 3.0E-32 T 01-11-2018 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 3.0E-32 T 01-11-2018 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 3.0E-32 T 01-11-2018 MLA2C4_23305 a1691850268106caab952576e31ba35c 556 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 3.0E-32 T 01-11-2018 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 453 5.4E-145 T 01-11-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Gene3D G3DSA:1.10.150.80 511 591 1.9E-25 T 01-11-2018 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SUPERFAMILY SSF46785 395 537 2.99E-35 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SMART SM00341 512 592 2.3E-21 T 01-11-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Gene3D G3DSA:1.10.10.10 334 510 1.8E-46 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Pfam PF00271 Helicase conserved C-terminal domain 219 323 4.8E-18 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Pfam PF14493 Helix-turn-helix domain 614 701 6.5E-26 T 01-11-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Pfam PF00270 DEAD/DEAH box helicase 21 181 4.9E-21 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Gene3D G3DSA:3.40.50.300 1 201 1.2E-75 T 01-11-2018 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SMART SM00487 14 211 8.0E-28 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SMART SM00490 243 324 1.3E-27 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Gene3D G3DSA:3.40.50.300 202 333 2.0E-40 T 01-11-2018 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SUPERFAMILY SSF47819 515 589 1.81E-24 T 01-11-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 5 583 3.4E-233 T 01-11-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SUPERFAMILY SSF52540 58 345 2.19E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Pfam PF09382 RQC domain 400 509 2.6E-31 T 01-11-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Pfam PF00570 HRDC domain 517 582 1.1E-22 T 01-11-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 Pfam PF16124 RecQ zinc-binding 336 396 4.1E-16 T 01-11-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MLA2C4_14895 cca32569904553081bd601edb7171c0d 705 SMART SM00956 404 507 2.1E-41 T 01-11-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 SUPERFAMILY SSF53720 4 485 1.23E-150 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 01-11-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 9 485 6.3E-181 T 01-11-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 3 485 74.217 T 01-11-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 Gene3D G3DSA:3.40.605.10 27 462 9.2E-151 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 Gene3D G3DSA:3.40.309.10 254 454 9.2E-151 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_12135 e942424eb2c50967833ca9cdb0bb8f45 486 Pfam PF00171 Aldehyde dehydrogenase family 17 481 1.5E-149 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_18165 e4d1f621a03bb05841eb55024549939c 396 Gene3D G3DSA:1.20.1250.20 2 193 3.9E-29 T 01-11-2018 MLA2C4_18165 e4d1f621a03bb05841eb55024549939c 396 Gene3D G3DSA:1.20.1250.20 203 396 5.6E-22 T 01-11-2018 MLA2C4_18165 e4d1f621a03bb05841eb55024549939c 396 Pfam PF07690 Major Facilitator Superfamily 20 360 1.5E-34 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_18165 e4d1f621a03bb05841eb55024549939c 396 SUPERFAMILY SSF103473 4 392 8.76E-57 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 Pfam PF07702 UTRA domain 95 234 1.6E-47 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 SMART SM00866 95 234 4.2E-51 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 SUPERFAMILY SSF46785 4 78 2.73E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 Gene3D G3DSA:1.10.10.10 8 74 3.5E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.1E-22 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 SUPERFAMILY SSF64288 62 241 3.14E-58 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.0E-9 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.0E-9 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 Gene3D G3DSA:3.40.1410.10 75 243 7.2E-59 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 10 236 5.3E-47 T 01-11-2018 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF MLA2C4_21195 eeb4947fdce1cdf5eb7530da0598e8e3 243 SMART SM00345 15 74 7.6E-24 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_12555 950511699e2fa7bf1384b356cd99fdfe 245 Gene3D G3DSA:3.40.630.40 3 165 9.5E-47 T 01-11-2018 MLA2C4_12555 950511699e2fa7bf1384b356cd99fdfe 245 SUPERFAMILY SSF53187 3 168 1.13E-36 T 01-11-2018 MLA2C4_12555 950511699e2fa7bf1384b356cd99fdfe 245 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 8 165 5.8E-28 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_12555 950511699e2fa7bf1384b356cd99fdfe 245 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 202 244 1.5E-23 T 01-11-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase MetaCyc: PWY-7883 MLA2C4_12555 950511699e2fa7bf1384b356cd99fdfe 245 Gene3D G3DSA:3.30.70.2030 166 245 4.3E-40 T 01-11-2018 MLA2C4_12555 950511699e2fa7bf1384b356cd99fdfe 245 SMART SM00646 65 167 2.0E-21 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_23860 062b5899b0937f8a76471d8222f4a731 430 SUPERFAMILY SSF53659 3 422 9.72E-142 T 01-11-2018 MLA2C4_23860 062b5899b0937f8a76471d8222f4a731 430 SMART SM01329 21 418 1.1E-185 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MLA2C4_23860 062b5899b0937f8a76471d8222f4a731 430 Gene3D G3DSA:3.40.718.10 1 423 7.8E-182 T 01-11-2018 MLA2C4_23860 062b5899b0937f8a76471d8222f4a731 430 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 423 5.5E-220 T 01-11-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MLA2C4_23860 062b5899b0937f8a76471d8222f4a731 430 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 9.8E-124 T 01-11-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MLA2C4_23860 062b5899b0937f8a76471d8222f4a731 430 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 01-11-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 2.2E-74 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 9.3E-35 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 Gene3D G3DSA:3.50.50.60 152 273 1.9E-126 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 Gene3D G3DSA:3.30.390.30 348 468 8.2E-43 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 4.6E-176 T 01-11-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 SUPERFAMILY SSF55424 346 468 1.15E-39 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 6.9E-42 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 6.9E-42 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 6.9E-42 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 6.9E-42 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 6.9E-42 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PIRSF PIRSF000350 3 459 1.6E-99 T 01-11-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 Gene3D G3DSA:3.50.50.60 13 335 1.9E-126 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 SUPERFAMILY SSF51905 8 340 1.18E-66 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 01-11-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 6.5E-76 T 01-11-2018 MLA2C4_20745 333ac707a4456dfee26c0896daef7b1f 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 6.5E-76 T 01-11-2018 MLA2C4_23155 bfd2f0dd8016b2e55c7fbdf7c02c46dc 182 Gene3D G3DSA:1.10.287.130 1 57 4.0E-20 T 01-11-2018 MLA2C4_23155 bfd2f0dd8016b2e55c7fbdf7c02c46dc 182 SMART SM01317 59 171 2.0E-61 T 01-11-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal MLA2C4_23155 bfd2f0dd8016b2e55c7fbdf7c02c46dc 182 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 5 55 6.2E-17 T 01-11-2018 IPR039506 SpoOB, alpha-helical domain MLA2C4_23155 bfd2f0dd8016b2e55c7fbdf7c02c46dc 182 Gene3D G3DSA:3.30.565.30 58 174 5.1E-31 T 01-11-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily MLA2C4_23155 bfd2f0dd8016b2e55c7fbdf7c02c46dc 182 SUPERFAMILY SSF55890 2 173 3.92E-62 T 01-11-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 MLA2C4_23155 bfd2f0dd8016b2e55c7fbdf7c02c46dc 182 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 60 169 2.5E-37 T 01-11-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal MLA2C4_27080 78964df313b4ccf83fec35e4a1b5ff9c 251 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 229 9.8E-5 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27080 78964df313b4ccf83fec35e4a1b5ff9c 251 SUPERFAMILY SSF55073 131 227 4.63E-6 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_27080 78964df313b4ccf83fec35e4a1b5ff9c 251 Gene3D G3DSA:3.30.70.270 112 243 4.0E-7 T 01-11-2018 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 7.4E-36 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 7.4E-36 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 7.4E-36 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 7.4E-36 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 7.4E-36 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 7.4E-36 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 Pfam PF00459 Inositol monophosphatase family 8 255 9.5E-64 T 01-11-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 Gene3D G3DSA:3.30.540.10 1 144 3.7E-45 T 01-11-2018 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 SUPERFAMILY SSF56655 5 262 1.7E-74 T 01-11-2018 MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 01-11-2018 IPR020583 Inositol monophosphatase, metal-binding site MLA2C4_20675 fa272c45eaf9865c67c37030c1346f1d 263 Gene3D G3DSA:3.40.190.80 146 263 3.8E-31 T 01-11-2018 MLA2C4_16015 a7313aa7098a38cb89738850fe4bc60b 169 Gene3D G3DSA:3.40.140.10 1 168 3.2E-38 T 01-11-2018 MLA2C4_16015 a7313aa7098a38cb89738850fe4bc60b 169 SUPERFAMILY SSF53927 3 122 1.05E-36 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_16015 a7313aa7098a38cb89738850fe4bc60b 169 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 105 8.4E-24 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MLA2C4_16015 a7313aa7098a38cb89738850fe4bc60b 169 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 95 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_25560 463f8675e554837a6076614c542e0b82 441 PRINTS PR00758 Arsenical pump membrane protein signature 286 310 1.5E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_25560 463f8675e554837a6076614c542e0b82 441 PRINTS PR00758 Arsenical pump membrane protein signature 378 403 1.5E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_25560 463f8675e554837a6076614c542e0b82 441 PRINTS PR00758 Arsenical pump membrane protein signature 110 134 1.5E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_25560 463f8675e554837a6076614c542e0b82 441 PRINTS PR00758 Arsenical pump membrane protein signature 227 252 1.5E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_25560 463f8675e554837a6076614c542e0b82 441 Pfam PF03600 Citrate transporter 24 382 5.2E-51 T 01-11-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MLA2C4_06655 008e7020ff3a40e1fdc8ad7f05245376 722 SUPERFAMILY SSF54814 666 721 6.54E-8 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MLA2C4_06655 008e7020ff3a40e1fdc8ad7f05245376 722 SUPERFAMILY SSF52540 81 254 5.14E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06655 008e7020ff3a40e1fdc8ad7f05245376 722 Pfam PF01926 50S ribosome-binding GTPase 102 207 2.9E-9 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_06655 008e7020ff3a40e1fdc8ad7f05245376 722 Gene3D G3DSA:3.30.300.20 658 722 7.1E-13 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_06655 008e7020ff3a40e1fdc8ad7f05245376 722 Gene3D G3DSA:3.40.50.300 6 315 1.0E-17 T 01-11-2018 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 SUPERFAMILY SSF50249 3 66 6.17E-24 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 Gene3D G3DSA:2.40.50.140 2 65 2.1E-28 T 01-11-2018 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 SMART SM00357 4 67 1.7E-27 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 PRINTS PR00050 Cold shock protein signature 40 58 3.0E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 PRINTS PR00050 Cold shock protein signature 5 20 3.0E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 PRINTS PR00050 Cold shock protein signature 25 34 3.0E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 01-11-2018 IPR019844 Cold-shock conserved site MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.2E-29 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_05950 a20e3bf76968c5a2466bab8267ccf4e5 67 PIRSF PIRSF002599 1 67 8.9E-25 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 SMART SM00490 254 335 1.3E-34 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 Pfam PF00271 Helicase conserved C-terminal domain 227 335 5.5E-29 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 522 47.363 T 01-11-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 SMART SM00487 21 218 6.1E-66 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 01-11-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 Gene3D G3DSA:3.40.50.300 211 433 6.2E-55 T 01-11-2018 MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 Pfam PF00270 DEAD/DEAH box helicase 26 190 1.1E-50 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 Gene3D G3DSA:3.40.50.300 1 207 3.5E-77 T 01-11-2018 MLA2C4_01390 2c827b11b56c69eb17128c4c05b8334b 527 SUPERFAMILY SSF52540 71 356 2.46E-75 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 SMART SM01274 16 149 2.6E-86 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 PIRSF PIRSF000106 37 408 6.4E-86 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 SUPERFAMILY SSF53223 7 159 1.58E-57 T 01-11-2018 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 SMART SM00919 161 385 2.0E-134 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 Gene3D G3DSA:3.40.50.10380 2 158 7.4E-75 T 01-11-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 SUPERFAMILY SSF51735 161 405 2.1E-83 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 PRINTS PR00072 Malic enzyme signature 157 173 1.5E-8 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 PRINTS PR00072 Malic enzyme signature 78 100 1.5E-8 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 PRINTS PR00072 Malic enzyme signature 188 204 1.5E-8 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 ProSitePatterns PS00331 Malic enzymes signature. 157 173 - T 01-11-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 Pfam PF00390 Malic enzyme, N-terminal domain 16 149 7.9E-31 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 Gene3D G3DSA:3.40.50.720 159 411 4.4E-88 T 01-11-2018 MLA2C4_23915 07d98dec99d682d3894bbf1905351d46 412 Pfam PF03949 Malic enzyme, NAD binding domain 163 384 1.4E-24 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 162 190 - T 01-11-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 SUPERFAMILY SSF52283 16 145 3.19E-31 T 01-11-2018 MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 122 301 3.1E-64 T 01-11-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 SUPERFAMILY SSF51735 114 302 1.14E-57 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 332 3.6E-30 T 01-11-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 Gene3D G3DSA:3.40.50.720 18 328 4.0E-115 T 01-11-2018 MLA2C4_25525 108289250ebeecb48b032e09ebb31aef 334 Gene3D G3DSA:3.40.50.720 111 301 4.0E-115 T 01-11-2018 MLA2C4_04185 3214da802b6dbf8b79840c12fc2e3047 504 Gene3D G3DSA:1.10.10.2600 138 286 8.6E-7 T 01-11-2018 IPR038109 DNA-binding recombinase domain superfamily MLA2C4_04185 3214da802b6dbf8b79840c12fc2e3047 504 Pfam PF07508 Recombinase 177 284 2.0E-8 T 01-11-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 MLA2C4_04185 3214da802b6dbf8b79840c12fc2e3047 504 SMART SM00857 4 154 9.5E-36 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_04185 3214da802b6dbf8b79840c12fc2e3047 504 Pfam PF00239 Resolvase, N terminal domain 5 145 3.4E-30 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_04185 3214da802b6dbf8b79840c12fc2e3047 504 Gene3D G3DSA:3.40.50.1390 2 136 5.7E-25 T 01-11-2018 MLA2C4_04185 3214da802b6dbf8b79840c12fc2e3047 504 SUPERFAMILY SSF53041 2 153 3.01E-27 T 01-11-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 SUPERFAMILY SSF140356 14 117 2.88E-39 T 01-11-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 SUPERFAMILY SSF56024 332 512 9.81E-57 T 01-11-2018 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Hamap MF_00347 Polyphosphate kinase [ppk]. 14 697 29.34 T 01-11-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 16 693 3.4E-285 T 01-11-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 SUPERFAMILY SSF143724 121 318 1.79E-60 T 01-11-2018 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 PIRSF PIRSF015589 2 702 4.6E-279 T 01-11-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Gene3D G3DSA:3.30.870.10 516 702 3.1E-72 T 01-11-2018 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Pfam PF13090 Polyphosphate kinase C-terminal domain 346 692 1.4E-155 T 01-11-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Pfam PF13089 Polyphosphate kinase N-terminal domain 17 122 3.5E-40 T 01-11-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Gene3D G3DSA:3.30.870.10 333 515 3.3E-74 T 01-11-2018 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 SUPERFAMILY SSF56024 516 698 2.47E-71 T 01-11-2018 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Gene3D G3DSA:3.30.1840.10 10 325 2.3E-111 T 01-11-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 MLA2C4_20875 b1ddd6536349e56e8d4ecf17ab85a754 702 Pfam PF02503 Polyphosphate kinase middle domain 132 337 2.7E-70 T 01-11-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 SUPERFAMILY SSF50104 2 113 3.51E-48 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 Pfam PF01245 Ribosomal protein L19 4 112 7.3E-53 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 114 32.171 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 PIRSF PIRSF002191 1 114 1.3E-50 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 3.9E-51 T 01-11-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 01-11-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20070 3a72cc94a8b0e7a34934c3d4c0964bc9 114 Gene3D G3DSA:2.30.30.790 10 114 5.8E-15 T 01-11-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_13470 254c5b4e0878bdae04ab76e996ccd8f6 71 Pfam PF00364 Biotin-requiring enzyme 9 70 1.8E-17 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_13470 254c5b4e0878bdae04ab76e996ccd8f6 71 Gene3D G3DSA:2.40.50.100 5 71 4.2E-25 T 01-11-2018 MLA2C4_13470 254c5b4e0878bdae04ab76e996ccd8f6 71 SUPERFAMILY SSF51230 3 71 7.07E-22 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 PIRSF PIRSF004911 3 401 3.3E-159 T 01-11-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 SUPERFAMILY SSF102114 114 355 6.41E-32 T 01-11-2018 MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 TIGRFAM TIGR00238 TIGR00238: KamA family protein 14 342 2.1E-146 T 01-11-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 21 427 3.6E-193 T 01-11-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 Pfam PF13353 4Fe-4S single cluster domain 127 199 7.9E-5 T 01-11-2018 MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 Gene3D G3DSA:2.40.50.600 349 414 1.2E-21 T 01-11-2018 MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 Pfam PF12544 Lysine-2,3-aminomutase 321 447 1.1E-61 T 01-11-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain MLA2C4_11495 b9d930cf51152573e49ae89494a50807 473 Gene3D G3DSA:3.20.20.70 63 348 2.9E-117 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 SUPERFAMILY SSF46689 5 62 1.23E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 SUPERFAMILY SSF48498 77 196 1.63E-27 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.6E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.6E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 Gene3D G3DSA:1.10.357.10 51 201 1.9E-52 T 01-11-2018 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.1E-13 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 Gene3D G3DSA:1.10.10.60 1 50 6.5E-24 T 01-11-2018 MLA2C4_18265 f678c4433a5610260a9b8e648c245105 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 50 193 1.7E-5 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 859 1007 9.1E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 1143 1273 8.7E-9 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 1347 1380 140.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 911 944 1.7E-5 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 123 156 150.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 189 222 350.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 1245 1278 320.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 733 766 0.21 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 664 697 0.63 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 1279 1312 0.079 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 767 800 400.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 563 596 49.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 597 630 21.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 1313 1346 33.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SMART SM00028 1011 1044 95.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:3.90.70.10 315 456 5.5E-14 T 01-11-2018 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SUPERFAMILY SSF48452 1141 1377 1.52E-18 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SUPERFAMILY SSF48452 123 245 8.85E-11 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 509 849 1.8E-39 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 1013 1142 2.6E-5 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SUPERFAMILY SSF48452 563 712 7.17E-23 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 194 300 2.3E-5 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Gene3D G3DSA:1.25.40.10 1274 1392 5.8E-15 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Pfam PF13181 Tetratricopeptide repeat 123 153 0.089 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Pfam PF13181 Tetratricopeptide repeat 914 943 3.4E-6 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Pfam PF13432 Tetratricopeptide repeat 738 786 0.0017 T 01-11-2018 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Pfam PF13432 Tetratricopeptide repeat 635 696 2.8E-5 T 01-11-2018 MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 Pfam PF13529 Peptidase_C39 like family 312 418 2.0E-15 T 01-11-2018 IPR039564 Peptidase C39-like MLA2C4_10995 3956a7dcf8436430962bb9353fbcb1aa 1400 SUPERFAMILY SSF48452 731 978 1.25E-16 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_21485 2937f4c382db6f7074442c16e3ad5da2 159 SUPERFAMILY SSF55729 37 126 4.18E-18 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21485 2937f4c382db6f7074442c16e3ad5da2 159 Pfam PF00583 Acetyltransferase (GNAT) family 33 118 7.6E-12 T 01-11-2018 IPR000182 GNAT domain MLA2C4_21485 2937f4c382db6f7074442c16e3ad5da2 159 Gene3D G3DSA:3.40.630.30 29 159 1.7E-21 T 01-11-2018 MLA2C4_09030 b931362febbb66a537ac75e73c0c1c57 184 ProSitePatterns PS00194 Thioredoxin family active site. 74 92 - T 01-11-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MLA2C4_09030 b931362febbb66a537ac75e73c0c1c57 184 Pfam PF00578 AhpC/TSA family 46 163 2.4E-26 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_09030 b931362febbb66a537ac75e73c0c1c57 184 SUPERFAMILY SSF52833 43 182 3.64E-44 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_09030 b931362febbb66a537ac75e73c0c1c57 184 Gene3D G3DSA:3.40.30.10 17 184 4.5E-45 T 01-11-2018 MLA2C4_28130 075f3215d1d7e8d2f3cbd76a69a49deb 487 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 137 285 7.8E-10 T 01-11-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 01-11-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 SMART SM00852 17 162 5.9E-34 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 PIRSF PIRSF006443 1 169 1.2E-69 T 01-11-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 Gene3D G3DSA:3.40.980.10 1 169 4.1E-53 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 1.2E-38 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 Pfam PF00994 Probable molybdopterin binding domain 18 161 5.7E-38 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_24795 be0cf15c06f2395f6acf683c401dbcf4 169 SUPERFAMILY SSF53218 8 165 7.98E-45 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_23250 de517c7f264a3b389cfbaed15c10c09d 325 SUPERFAMILY SSF54106 274 319 4.45E-10 T 01-11-2018 MLA2C4_23250 de517c7f264a3b389cfbaed15c10c09d 325 Pfam PF01476 LysM domain 276 318 1.1E-7 T 01-11-2018 IPR018392 LysM domain MLA2C4_23250 de517c7f264a3b389cfbaed15c10c09d 325 Gene3D G3DSA:3.10.350.10 263 325 6.4E-11 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_23250 de517c7f264a3b389cfbaed15c10c09d 325 SMART SM00257 275 318 9.9E-7 T 01-11-2018 IPR018392 LysM domain MLA2C4_23250 de517c7f264a3b389cfbaed15c10c09d 325 TIGRFAM TIGR02907 spore_VI_D: stage VI sporulation protein D 7 318 4.2E-125 T 01-11-2018 IPR014256 Sporulation stage VI, protein D MLA2C4_23475 88de719852c1e6994843d101d34687d6 148 Pfam PF03061 Thioesterase superfamily 33 118 7.4E-15 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_23475 88de719852c1e6994843d101d34687d6 148 SUPERFAMILY SSF54637 13 147 1.07E-33 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_23475 88de719852c1e6994843d101d34687d6 148 Gene3D G3DSA:3.10.129.10 7 148 7.6E-34 T 01-11-2018 MLA2C4_01420 4b682577e07d0a759bac6defa2d4c5e6 95 Gene3D G3DSA:1.10.1220.10 1 95 8.6E-33 T 01-11-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MLA2C4_21340 6a742840fe986d13ff4e2c0ff432b1d8 293 SUPERFAMILY SSF52540 2 219 8.56E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21340 6a742840fe986d13ff4e2c0ff432b1d8 293 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_21340 6a742840fe986d13ff4e2c0ff432b1d8 293 Pfam PF00005 ABC transporter 17 154 3.3E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_21340 6a742840fe986d13ff4e2c0ff432b1d8 293 Gene3D G3DSA:3.40.50.300 1 246 9.8E-52 T 01-11-2018 MLA2C4_21340 6a742840fe986d13ff4e2c0ff432b1d8 293 SMART SM00382 26 202 1.5E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 SUPERFAMILY SSF46589 16 100 1.2E-21 T 01-11-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 5.2E-112 T 01-11-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 5.4E-24 T 01-11-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 SUPERFAMILY SSF55681 93 342 1.59E-83 T 01-11-2018 MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 Gene3D G3DSA:3.30.930.10 8 343 4.2E-126 T 01-11-2018 MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 1.4E-115 T 01-11-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MLA2C4_23700 586e6c14062d8ab6fcf04ac55cb1284a 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.957 T 01-11-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 Gene3D G3DSA:3.30.750.80 74 181 4.3E-37 T 01-11-2018 MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 SUPERFAMILY SSF53335 81 393 4.59E-64 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 112 381 1.6E-30 T 01-11-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 SUPERFAMILY SSF88697 6 74 1.61E-20 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 SMART SM00359 5 90 7.5E-6 T 01-11-2018 IPR002478 PUA domain GO:0003723 MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 Gene3D G3DSA:2.30.130.10 5 73 1.1E-21 T 01-11-2018 IPR036974 PUA domain superfamily GO:0003723 MLA2C4_23600 8cb3980c192f93fa55b169eca3e66916 399 Gene3D G3DSA:3.40.50.150 182 398 1.7E-54 T 01-11-2018 MLA2C4_24410 d5b6ec33792c33fbc795eaf8ad6b7f58 270 Hamap MF_01548 UPF0354 protein . 3 264 48.419 T 01-11-2018 IPR010838 Protein of unknown unction DUF1444 MLA2C4_24410 d5b6ec33792c33fbc795eaf8ad6b7f58 270 PIRSF PIRSF012562 1 264 2.2E-138 T 01-11-2018 IPR010838 Protein of unknown unction DUF1444 MLA2C4_24410 d5b6ec33792c33fbc795eaf8ad6b7f58 270 Pfam PF07285 Protein of unknown function (DUF1444) 3 263 8.6E-122 T 01-11-2018 IPR010838 Protein of unknown unction DUF1444 MLA2C4_24990 2fb38cf55da92066b1d389cd0e835def 290 PIRSF PIRSF006483 1 289 9.2E-76 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_24990 2fb38cf55da92066b1d389cd0e835def 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 227 281 3.2E-19 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_24990 2fb38cf55da92066b1d389cd0e835def 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 221 7.3E-49 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_24990 2fb38cf55da92066b1d389cd0e835def 290 Gene3D G3DSA:3.30.70.120 199 273 5.4E-15 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_14160 d5a563ae355fd5b7d85f61fdcf7e2bbf 210 Pfam PF04892 VanZ like family 44 184 7.8E-24 T 01-11-2018 IPR006976 VanZ-like MLA2C4_02155 48601603c7186835d55f2afed0693273 252 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 31 127 1.6E-25 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MLA2C4_02155 48601603c7186835d55f2afed0693273 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 52 233 7.6E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_02155 48601603c7186835d55f2afed0693273 252 Gene3D G3DSA:1.10.3720.10 21 237 1.3E-55 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_02155 48601603c7186835d55f2afed0693273 252 SUPERFAMILY SSF161098 32 234 2.09E-45 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_16995 ccf6d219da249e2695864157ea082ab8 306 Pfam PF04072 Leucine carboxyl methyltransferase 13 207 1.0E-48 T 01-11-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MLA2C4_16995 ccf6d219da249e2695864157ea082ab8 306 Gene3D G3DSA:3.40.50.150 4 305 9.5E-48 T 01-11-2018 MLA2C4_16995 ccf6d219da249e2695864157ea082ab8 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 286 6.4E-44 T 01-11-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 MLA2C4_16995 ccf6d219da249e2695864157ea082ab8 306 SUPERFAMILY SSF53335 9 305 3.13E-62 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_18650 cc2d5c0444a1069032f7c9515c4a88ee 316 Gene3D G3DSA:1.10.10.10 1 62 2.4E-6 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18650 cc2d5c0444a1069032f7c9515c4a88ee 316 SUPERFAMILY SSF46785 1 60 2.0E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_18650 cc2d5c0444a1069032f7c9515c4a88ee 316 SMART SM00420 6 59 0.0038 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_18650 cc2d5c0444a1069032f7c9515c4a88ee 316 Pfam PF08279 HTH domain 6 58 8.8E-9 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_18650 cc2d5c0444a1069032f7c9515c4a88ee 316 Pfam PF13280 WYL domain 139 302 8.5E-18 T 01-11-2018 IPR026881 WYL domain MLA2C4_06815 6656ce4537426e0880a3f88112b64732 197 Pfam PF12389 Camelysin metallo-endopeptidase 2 194 4.4E-90 T 01-11-2018 IPR022121 Peptidase M73, camelysin MLA2C4_06815 6656ce4537426e0880a3f88112b64732 197 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 4.8E-14 T 01-11-2018 IPR023833 Signal peptide, camelysin MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 01-11-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 SMART SM01134 73 231 1.6E-62 T 01-11-2018 MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.9E-8 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.9E-8 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 SUPERFAMILY SSF100950 74 231 1.88E-36 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 5.4E-17 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 SMART SM00420 6 58 3.6E-18 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 SUPERFAMILY SSF46785 5 78 4.67E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 Gene3D G3DSA:1.10.10.10 8 66 4.7E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19420 64b017626db1a2aa1dc2d23a549e641f 250 Pfam PF00455 DeoR C terminal sensor domain 75 228 6.3E-47 T 01-11-2018 IPR014036 DeoR C-terminal sensor domain MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 SUPERFAMILY SSF52540 1049 1341 3.89E-49 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 Gene3D G3DSA:3.30.980.40 969 1072 6.6E-36 T 01-11-2018 MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 Gene3D G3DSA:1.10.10.10 1357 1424 4.8E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 SMART SM00843 1363 1428 3.5E-37 T 01-11-2018 IPR018541 FtsK gamma domain MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 SUPERFAMILY SSF46785 1364 1429 7.98E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 Gene3D G3DSA:3.40.50.300 1073 1352 7.1E-112 T 01-11-2018 MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 Pfam PF09397 Ftsk gamma domain 1365 1425 1.5E-27 T 01-11-2018 IPR018541 FtsK gamma domain MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 Pfam PF01580 FtsK/SpoIIIE family 1076 1208 6.4E-47 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_24390 c1a69907249674e2dab7abe76689c316 1438 Pfam PF01580 FtsK/SpoIIIE family 1217 1268 1.2E-15 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 SUPERFAMILY SSF52172 2 127 8.82E-41 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 SMART SM00862 153 229 1.1E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 Pfam PF00072 Response regulator receiver domain 5 114 4.3E-29 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 SMART SM00448 3 113 6.8E-42 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 Gene3D G3DSA:3.40.50.2300 1 132 3.5E-37 T 01-11-2018 MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 Gene3D G3DSA:1.10.10.10 134 231 1.3E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 SUPERFAMILY SSF46894 129 229 3.4E-29 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_13530 d05c3f591c4a436e16a63ad1979525a6 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 1.0E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 SUPERFAMILY SSF51569 1 289 8.9E-88 T 01-11-2018 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 9 291 5.3E-71 T 01-11-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 Gene3D G3DSA:3.20.20.70 1 294 2.3E-95 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 SMART SM01130 3 293 9.5E-105 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 Pfam PF00701 Dihydrodipicolinate synthetase family 4 291 8.2E-73 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 291 39.409 T 01-11-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 01-11-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 1.2E-20 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.2E-20 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.2E-20 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.2E-20 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_14980 4adfe2c3dbecf80f00e9dd650abe0479 298 PIRSF PIRSF001365 1 298 1.1E-98 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_07330 fb79062d95e00b1fe9bf3e707df97e3d 143 Pfam PF14184 Regulatory protein YrvL 15 140 5.4E-38 T 01-11-2018 IPR025912 Regulatory protein YrvL MLA2C4_07240 1f18bdedee057175af6322490a2db1b9 306 SUPERFAMILY SSF141986 141 294 4.32E-44 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_07240 1f18bdedee057175af6322490a2db1b9 306 Pfam PF02016 LD-carboxypeptidase 13 287 1.9E-81 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_07240 1f18bdedee057175af6322490a2db1b9 306 PIRSF PIRSF028757 1 301 1.4E-90 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_07240 1f18bdedee057175af6322490a2db1b9 306 Gene3D G3DSA:3.40.50.10740 1 152 3.5E-54 T 01-11-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal MLA2C4_07240 1f18bdedee057175af6322490a2db1b9 306 Gene3D G3DSA:3.50.30.60 163 295 6.8E-44 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_07240 1f18bdedee057175af6322490a2db1b9 306 SUPERFAMILY SSF52317 1 157 1.42E-50 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_11135 fb93912a2a4e938cb6f193921c65fdfb 175 SUPERFAMILY SSF56784 2 173 1.15E-36 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_11135 fb93912a2a4e938cb6f193921c65fdfb 175 Pfam PF13242 HAD-hyrolase-like 91 167 5.2E-17 T 01-11-2018 MLA2C4_11135 fb93912a2a4e938cb6f193921c65fdfb 175 Gene3D G3DSA:3.40.50.1000 5 175 3.3E-44 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_11135 fb93912a2a4e938cb6f193921c65fdfb 175 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 133 6.1E-26 T 01-11-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MLA2C4_11135 fb93912a2a4e938cb6f193921c65fdfb 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 138 1.2E-23 T 01-11-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MLA2C4_11135 fb93912a2a4e938cb6f193921c65fdfb 175 PIRSF PIRSF004682 1 172 6.1E-41 T 01-11-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MLA2C4_15160 5f745231154be3e231eae6350c901992 463 SUPERFAMILY SSF56784 197 455 8.27E-43 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_15160 5f745231154be3e231eae6350c901992 463 Gene3D G3DSA:3.40.50.1580 1 231 2.9E-63 T 01-11-2018 MLA2C4_15160 5f745231154be3e231eae6350c901992 463 Gene3D G3DSA:1.10.150.240 255 328 1.0E-30 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_15160 5f745231154be3e231eae6350c901992 463 Gene3D G3DSA:3.40.50.1000 244 444 1.0E-30 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_15160 5f745231154be3e231eae6350c901992 463 SUPERFAMILY SSF53167 3 229 3.4E-62 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MLA2C4_15160 5f745231154be3e231eae6350c901992 463 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 227 1.0E-52 T 01-11-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_15160 5f745231154be3e231eae6350c901992 463 Pfam PF01048 Phosphorylase superfamily 3 224 6.4E-51 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MLA2C4_15160 5f745231154be3e231eae6350c901992 463 Pfam PF13419 Haloacid dehalogenase-like hydrolase 244 424 5.6E-14 T 01-11-2018 MLA2C4_11325 40d52c1a3b9d9f8b4c18b229ff88a5ee 284 Pfam PF01380 SIS domain 130 258 6.0E-23 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_11325 40d52c1a3b9d9f8b4c18b229ff88a5ee 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 78 2.4E-21 T 01-11-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MLA2C4_11325 40d52c1a3b9d9f8b4c18b229ff88a5ee 284 Gene3D G3DSA:1.10.10.10 3 84 1.4E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_11325 40d52c1a3b9d9f8b4c18b229ff88a5ee 284 Gene3D G3DSA:3.40.50.10490 98 283 1.3E-51 T 01-11-2018 MLA2C4_11325 40d52c1a3b9d9f8b4c18b229ff88a5ee 284 SUPERFAMILY SSF53697 94 281 1.09E-45 T 01-11-2018 MLA2C4_11325 40d52c1a3b9d9f8b4c18b229ff88a5ee 284 SUPERFAMILY SSF46689 8 80 2.15E-20 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_13615 67a6a1f069f26e50db87b438c2c89e7f 483 SUPERFAMILY SSF56601 33 356 2.82E-72 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13615 67a6a1f069f26e50db87b438c2c89e7f 483 Gene3D G3DSA:3.40.710.10 26 365 1.8E-84 T 01-11-2018 MLA2C4_13615 67a6a1f069f26e50db87b438c2c89e7f 483 Pfam PF00144 Beta-lactamase 37 353 1.6E-58 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_01305 9bc6411e2757d4e5e80e13e0b69d568a 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 307 2.7E-30 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_01305 9bc6411e2757d4e5e80e13e0b69d568a 307 Gene3D G3DSA:1.10.3720.10 85 307 2.5E-23 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01305 9bc6411e2757d4e5e80e13e0b69d568a 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 73 2.2E-13 T 01-11-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MLA2C4_01305 9bc6411e2757d4e5e80e13e0b69d568a 307 SUPERFAMILY SSF161098 91 285 4.84E-23 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_07060 b322a22a2a25f909f4dd64e5b0bb5117 209 SUPERFAMILY SSF53639 7 204 5.69E-29 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MLA2C4_07060 b322a22a2a25f909f4dd64e5b0bb5117 209 SMART SM01007 9 196 3.3E-16 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal MLA2C4_07060 b322a22a2a25f909f4dd64e5b0bb5117 209 Gene3D G3DSA:3.40.225.10 8 209 3.4E-23 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MLA2C4_07060 b322a22a2a25f909f4dd64e5b0bb5117 209 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 193 4.2E-21 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal MLA2C4_07060 b322a22a2a25f909f4dd64e5b0bb5117 209 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 204 71.27 T 01-11-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 SUPERFAMILY SSF51338 1 424 4.96E-31 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 Gene3D G3DSA:2.30.40.10 7 419 1.4E-174 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 SUPERFAMILY SSF51556 54 367 9.04E-115 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 Pfam PF01979 Amidohydrolase family 51 419 7.9E-53 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 Gene3D G3DSA:3.20.20.140 54 366 1.4E-174 T 01-11-2018 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 423 45.866 T 01-11-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 01-11-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 01-11-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20325 b0b8ea737fa3539ebefda105a296f0c9 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 422 2.8E-154 T 01-11-2018 MLA2C4_03705 125cb6213445408dacab02b5d53bf66e 471 Gene3D G3DSA:1.20.1740.10 9 469 1.6E-68 T 01-11-2018 MLA2C4_03705 125cb6213445408dacab02b5d53bf66e 471 PIRSF PIRSF006060 1 469 6.8E-85 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_03705 125cb6213445408dacab02b5d53bf66e 471 Pfam PF00324 Amino acid permease 18 458 6.8E-128 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_03705 125cb6213445408dacab02b5d53bf66e 471 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_22020 335ae6fb42392a261d6243e4dde2dbf1 278 Gene3D G3DSA:3.30.930.10 4 278 4.1E-69 T 01-11-2018 MLA2C4_22020 335ae6fb42392a261d6243e4dde2dbf1 278 SUPERFAMILY SSF55681 5 278 2.98E-68 T 01-11-2018 MLA2C4_22020 335ae6fb42392a261d6243e4dde2dbf1 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.116 T 01-11-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MLA2C4_22020 335ae6fb42392a261d6243e4dde2dbf1 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 6.2E-28 T 01-11-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MLA2C4_02305 df07c59d205999070f0ec1f8cf6e491d 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 249 3.0E-25 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_02305 df07c59d205999070f0ec1f8cf6e491d 257 Gene3D G3DSA:1.10.3720.10 49 247 1.0E-23 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_02305 df07c59d205999070f0ec1f8cf6e491d 257 SUPERFAMILY SSF161098 53 237 1.2E-29 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 SMART SM00448 174 297 2.2E-20 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 SMART SM00260 13 149 1.1E-29 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 Gene3D G3DSA:2.30.30.40 19 143 2.9E-34 T 01-11-2018 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 Gene3D G3DSA:2.40.50.180 34 149 2.9E-34 T 01-11-2018 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 SUPERFAMILY SSF52172 173 300 1.99E-23 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 SUPERFAMILY SSF50341 7 150 1.57E-34 T 01-11-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 Pfam PF01584 CheW-like domain 18 149 2.4E-36 T 01-11-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 PIRSF PIRSF002867 1 302 1.4E-94 T 01-11-2018 IPR024181 Chemotaxis response regulator CheV MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 Gene3D G3DSA:3.40.50.2300 169 302 3.8E-24 T 01-11-2018 MLA2C4_08660 2b75a885e0b25f30b7b69ad1497f8fc8 302 Pfam PF00072 Response regulator receiver domain 176 296 4.2E-20 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 5.6E-118 T 01-11-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 3.2E-35 T 01-11-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 SUPERFAMILY SSF52540 183 433 6.2E-54 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 Gene3D G3DSA:3.40.50.300 167 448 2.5E-117 T 01-11-2018 MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 SUPERFAMILY SSF48024 8 119 5.1E-38 T 01-11-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 Gene3D G3DSA:1.10.860.10 1 166 3.0E-64 T 01-11-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MLA2C4_28380 0723a795f1acede097716294636b8d5d 449 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 442 4.2E-187 T 01-11-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 25 154 1.7E-6 T 01-11-2018 MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 Gene3D G3DSA:3.10.180.10 175 372 2.2E-83 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 179 326 4.3E-18 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 SUPERFAMILY SSF54593 12 359 1.63E-91 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 PIRSF PIRSF009283 7 372 8.6E-142 T 01-11-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 21 372 7.5E-147 T 01-11-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MLA2C4_01355 848905088898fe3ac60668d3c6eba6f4 372 Gene3D G3DSA:3.10.180.10 4 172 2.0E-54 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_28295 6d12823ce7a39f024459a84360f1328d 605 SUPERFAMILY SSF55486 10 584 1.52E-110 T 01-11-2018 MLA2C4_28295 6d12823ce7a39f024459a84360f1328d 605 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 11 601 1.6E-227 T 01-11-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 MLA2C4_28295 6d12823ce7a39f024459a84360f1328d 605 Pfam PF08439 Oligopeptidase F 118 187 4.0E-20 T 01-11-2018 IPR013647 Oligopeptidase F, N-terminal domain MLA2C4_28295 6d12823ce7a39f024459a84360f1328d 605 Pfam PF01432 Peptidase family M3 213 589 2.2E-38 T 01-11-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MLA2C4_28295 6d12823ce7a39f024459a84360f1328d 605 Gene3D G3DSA:1.10.1370.20 233 605 2.9E-119 T 01-11-2018 MLA2C4_28295 6d12823ce7a39f024459a84360f1328d 605 Gene3D G3DSA:1.20.140.70 28 183 2.0E-43 T 01-11-2018 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 Pfam PF00672 HAMP domain 217 264 3.4E-6 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 SMART SM00304 216 268 1.7E-6 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 525 1.4E-48 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 Gene3D G3DSA:1.10.287.950 242 572 8.6E-70 T 01-11-2018 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 59 74 3.7E-21 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 424 453 3.7E-21 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 422 3.7E-21 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 SUPERFAMILY SSF58104 236 571 1.27E-71 T 01-11-2018 MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 188 2.8E-15 T 01-11-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain MLA2C4_05910 c45e2046c3ecd292d976b2e9ca437233 575 SMART SM00283 297 572 1.4E-71 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Pfam PF00689 Cation transporting ATPase, C-terminus 716 881 1.6E-51 T 01-11-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 4.5E-18 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 664 689 4.5E-18 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 604 620 4.5E-18 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 4.5E-18 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 SUPERFAMILY SSF56784 322 736 1.41E-65 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Pfam PF00122 E1-E2 ATPase 111 304 9.0E-55 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Gene3D G3DSA:1.20.1110.10 54 877 0.0 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 646 4.7E-28 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 599 722 6.3E-38 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 345 2.4E-45 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 2.3E-16 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 SUPERFAMILY SSF81660 332 534 4.58E-57 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 9.5E-41 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 9.5E-41 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 9.5E-41 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 9.5E-41 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 9.5E-41 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 9.5E-41 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 SMART SM00831 2 76 1.0E-24 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Gene3D G3DSA:3.40.50.1000 321 677 0.0 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 SUPERFAMILY SSF81665 1 881 1.02E-135 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 53 881 2.6E-216 T 01-11-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Gene3D G3DSA:3.40.1110.10 334 537 0.0 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 Gene3D G3DSA:2.70.150.10 16 227 0.0 T 01-11-2018 MLA2C4_20245 c8ef297231fbf3a208647feeafde03f8 907 SUPERFAMILY SSF81653 114 224 2.09E-31 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_15385 2cea8bf4cbf7cd38a8627943155a2468 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 1.6E-25 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_15385 2cea8bf4cbf7cd38a8627943155a2468 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 3.5E-21 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_04795 5b908bccbe571f93ed05e1054134f1ff 833 Pfam PF00395 S-layer homology domain 156 197 4.6E-5 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04795 5b908bccbe571f93ed05e1054134f1ff 833 Pfam PF00395 S-layer homology domain 33 76 8.0E-12 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04795 5b908bccbe571f93ed05e1054134f1ff 833 Pfam PF00395 S-layer homology domain 95 135 2.4E-5 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04795 5b908bccbe571f93ed05e1054134f1ff 833 Gene3D G3DSA:2.60.40.1220 721 828 3.1E-7 T 01-11-2018 MLA2C4_04795 5b908bccbe571f93ed05e1054134f1ff 833 Gene3D G3DSA:2.60.40.1220 622 711 4.1E-6 T 01-11-2018 MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 SUPERFAMILY SSF141868 4 256 7.45E-42 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 Pfam PF10388 EAL-domain associated signalling protein domain 240 404 4.6E-80 T 01-11-2018 IPR018842 YkuI, C-terminal MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 SUPERFAMILY SSF103190 263 400 5.41E-43 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 Gene3D G3DSA:1.20.5.170 246 290 1.8E-13 T 01-11-2018 MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 Gene3D G3DSA:3.20.20.450 1 229 4.0E-59 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 SMART SM00052 3 241 2.1E-12 T 01-11-2018 IPR001633 EAL domain MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 Gene3D G3DSA:3.30.450.20 291 405 2.0E-43 T 01-11-2018 MLA2C4_20850 41ccfd0e2715ed9225716d0751f1536c 405 Pfam PF00563 EAL domain 12 233 4.1E-29 T 01-11-2018 IPR001633 EAL domain MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 SUPERFAMILY SSF53187 175 489 6.28E-114 T 01-11-2018 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 SUPERFAMILY SSF52949 10 175 5.06E-33 T 01-11-2018 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 340 347 - T 01-11-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 493 35.179 T 01-11-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 484 5.9E-117 T 01-11-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 PRINTS PR00481 Cytosol aminopeptidase signature 314 335 1.5E-50 T 01-11-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 PRINTS PR00481 Cytosol aminopeptidase signature 336 356 1.5E-50 T 01-11-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 PRINTS PR00481 Cytosol aminopeptidase signature 277 298 1.5E-50 T 01-11-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 PRINTS PR00481 Cytosol aminopeptidase signature 364 379 1.5E-50 T 01-11-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 PRINTS PR00481 Cytosol aminopeptidase signature 255 272 1.5E-50 T 01-11-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 Gene3D G3DSA:3.40.630.10 165 490 7.9E-126 T 01-11-2018 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 15 143 4.4E-28 T 01-11-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MLA2C4_25615 f8a606ca934e28c4cf135d69aa450219 494 Gene3D G3DSA:3.40.220.10 1 151 6.0E-35 T 01-11-2018 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 SUPERFAMILY SSF144052 3 408 5.89E-152 T 01-11-2018 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 2.4E-74 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 Pfam PF02073 Thermophilic metalloprotease (M29) 4 407 5.0E-177 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_01950 0637a8380c9f5cedf27b70a526018cb0 409 Gene3D G3DSA:3.40.1830.10 1 179 1.8E-70 T 01-11-2018 IPR035097 Peptidase M29, N-terminal MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 PIRSF PIRSF039088 1 501 5.8E-251 T 01-11-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Gene3D G3DSA:3.40.50.300 94 371 5.7E-128 T 01-11-2018 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Gene3D G3DSA:2.40.30.20 1 93 2.6E-37 T 01-11-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 4.5E-259 T 01-11-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 SUPERFAMILY SSF50615 10 94 7.46E-31 T 01-11-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 01-11-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.704 T 01-11-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 486 2.4E-46 T 01-11-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 SUPERFAMILY SSF52540 95 370 2.15E-99 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Gene3D G3DSA:1.20.150.20 372 499 5.1E-51 T 01-11-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.2E-20 T 01-11-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 2.3E-73 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27470 f64a3fd13f3afe6710dcad880281bbda 502 SUPERFAMILY SSF47917 372 500 2.46E-47 T 01-11-2018 MLA2C4_19025 488552ae3b903c300c27ac4bb40667a5 642 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 107 353 5.7E-41 T 01-11-2018 IPR000477 Reverse transcriptase domain MLA2C4_19025 488552ae3b903c300c27ac4bb40667a5 642 SUPERFAMILY SSF56672 53 360 5.27E-45 T 01-11-2018 MLA2C4_19025 488552ae3b903c300c27ac4bb40667a5 642 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 50 442 3.6E-109 T 01-11-2018 IPR030931 Group II intron reverse transcriptase/maturase MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 434 450 - T 01-11-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Gene3D G3DSA:3.30.413.10 389 527 1.2E-33 T 01-11-2018 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 PRINTS PR00397 Sirohaem Fe-binding site signature 434 452 2.7E-8 T 01-11-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 PRINTS PR00397 Sirohaem Fe-binding site signature 390 408 2.7E-8 T 01-11-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Gene3D G3DSA:3.30.413.10 127 307 1.8E-137 T 01-11-2018 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 SUPERFAMILY SSF55124 14 134 1.6E-29 T 01-11-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 313 375 5.0E-16 T 01-11-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 62 125 5.9E-19 T 01-11-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 SUPERFAMILY SSF56014 135 292 1.03E-40 T 01-11-2018 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Gene3D G3DSA:3.90.480.20 13 378 1.8E-137 T 01-11-2018 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 SUPERFAMILY SSF55124 270 401 3.05E-22 T 01-11-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 393 529 7.6E-11 T 01-11-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 135 290 1.3E-33 T 01-11-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MLA2C4_07525 a33922b034fa82341fc5ab67e991847a 540 SUPERFAMILY SSF56014 388 526 2.22E-32 T 01-11-2018 MLA2C4_20165 88b9a2b59d0bfaf1854e4c847f637a04 26 Pfam PF08183 Stage V sporulation protein family 1 25 2.1E-17 T 01-11-2018 IPR012609 Sporulation stage V, protein M MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 PRINTS PR01607 Apyrase family signature 251 274 9.8E-26 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 PRINTS PR01607 Apyrase family signature 465 484 9.8E-26 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 PRINTS PR01607 Apyrase family signature 277 297 9.8E-26 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 PRINTS PR01607 Apyrase family signature 394 417 9.8E-26 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 PRINTS PR01607 Apyrase family signature 36 54 9.8E-26 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 PRINTS PR01607 Apyrase family signature 222 239 9.8E-26 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 Gene3D G3DSA:3.60.21.10 34 341 4.6E-86 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 ProSitePatterns PS00786 5'-nucleotidase signature 2. 114 125 - T 01-11-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 Pfam PF00149 Calcineurin-like phosphoesterase 41 269 3.0E-13 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 SUPERFAMILY SSF56300 33 341 5.93E-82 T 01-11-2018 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 SUPERFAMILY SSF55816 339 527 1.7E-57 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 Gene3D G3DSA:3.90.780.10 344 528 4.3E-59 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21460 d2e3da7102696f0feea7a26495e5c75c 529 Pfam PF02872 5'-nucleotidase, C-terminal domain 342 490 5.2E-49 T 01-11-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_03270 abeb81a21fb36295b9f3cd21af4fb08a 321 SUPERFAMILY SSF51735 1 313 5.28E-55 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_03270 abeb81a21fb36295b9f3cd21af4fb08a 321 Gene3D G3DSA:3.40.50.720 1 317 2.7E-104 T 01-11-2018 MLA2C4_03270 abeb81a21fb36295b9f3cd21af4fb08a 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 240 4.9E-27 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_08815 58013513f477d2a9d7688071c3ee5990 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.2E-27 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_08815 58013513f477d2a9d7688071c3ee5990 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.744 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_08815 58013513f477d2a9d7688071c3ee5990 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 6.0E-22 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_08815 58013513f477d2a9d7688071c3ee5990 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 1.0E-25 T 01-11-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 MLA2C4_09020 f85e97b3229ae2b8f74206036c9d88e1 270 Gene3D G3DSA:3.30.2010.10 87 157 5.6E-7 T 01-11-2018 MLA2C4_09020 f85e97b3229ae2b8f74206036c9d88e1 270 Pfam PF05569 BlaR1 peptidase M56 57 232 2.2E-12 T 01-11-2018 IPR008756 Peptidase M56 MLA2C4_11410 a8bba12c4d4af4bebd4f24bf76070f29 475 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 9 474 7.9E-172 T 01-11-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 MLA2C4_11410 a8bba12c4d4af4bebd4f24bf76070f29 475 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 10 474 2.5E-178 T 01-11-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 MLA2C4_11410 a8bba12c4d4af4bebd4f24bf76070f29 475 Gene3D G3DSA:1.20.1740.10 7 462 2.0E-65 T 01-11-2018 MLA2C4_11410 a8bba12c4d4af4bebd4f24bf76070f29 475 PIRSF PIRSF006060 4 451 1.8E-59 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_11410 a8bba12c4d4af4bebd4f24bf76070f29 475 Pfam PF13520 Amino acid permease 12 414 3.8E-68 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 Pfam PF01205 Uncharacterized protein family UPF0029 19 122 4.3E-33 T 01-11-2018 IPR001498 Impact, N-terminal MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 SUPERFAMILY SSF54980 135 200 7.12E-11 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 01-11-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 Gene3D G3DSA:3.30.230.30 2 133 4.7E-51 T 01-11-2018 IPR036956 Impact, N-terminal domain superfamily MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.7E-18 T 01-11-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 SUPERFAMILY SSF54211 3 131 6.07E-44 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_26885 98ab0be0f561af7b264a10251778ab5f 211 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 201 1.4E-77 T 01-11-2018 IPR015796 Impact family, bacterial/archaeal MLA2C4_22105 39430dc75953b44c2938ae770a09782a 491 SUPERFAMILY SSF53383 12 483 2.88E-112 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22105 39430dc75953b44c2938ae770a09782a 491 Pfam PF02347 Glycine cleavage system P-protein 51 300 4.0E-10 T 01-11-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MLA2C4_22105 39430dc75953b44c2938ae770a09782a 491 Gene3D G3DSA:3.40.640.10 86 323 2.8E-57 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_22105 39430dc75953b44c2938ae770a09782a 491 Gene3D G3DSA:3.90.1150.10 338 470 3.1E-47 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22105 39430dc75953b44c2938ae770a09782a 491 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.631 T 01-11-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 Gene3D G3DSA:3.40.1360.20 1 119 1.0E-25 T 01-11-2018 MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 SMART SM00493 4 77 1.0E-6 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 178 32.804 T 01-11-2018 IPR004466 Ribonuclease M5 GO:0043822 MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 Pfam PF13331 Domain of unknown function (DUF4093) 93 175 2.4E-27 T 01-11-2018 IPR025156 Ribonuclease M5, C-terminal domain MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 175 2.3E-64 T 01-11-2018 IPR004466 Ribonuclease M5 GO:0043822 MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 Pfam PF13662 Toprim domain 4 70 4.7E-7 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_00235 e8c46799106f74c1c8f00b3b0aa7243e 185 SUPERFAMILY SSF110455 1 114 4.18E-36 T 01-11-2018 MLA2C4_15425 2a734281a8c4fc75b33c2b46536e0ddf 370 SUPERFAMILY SSF51679 1 349 2.49E-100 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_15425 2a734281a8c4fc75b33c2b46536e0ddf 370 Gene3D G3DSA:3.20.20.30 1 358 6.2E-146 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_15425 2a734281a8c4fc75b33c2b46536e0ddf 370 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 370 76.884 T 01-11-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 MLA2C4_15425 2a734281a8c4fc75b33c2b46536e0ddf 370 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 1.6E-189 T 01-11-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 MLA2C4_15425 2a734281a8c4fc75b33c2b46536e0ddf 370 Pfam PF00296 Luciferase-like monooxygenase 1 323 1.4E-91 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 Pfam PF01979 Amidohydrolase family 53 361 2.0E-22 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 370 9.2E-102 T 01-11-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 Gene3D G3DSA:2.30.40.10 11 373 7.3E-129 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 SUPERFAMILY SSF51338 5 376 6.79E-13 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 Gene3D G3DSA:3.20.20.140 57 347 7.3E-129 T 01-11-2018 MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 SUPERFAMILY SSF51556 57 346 6.96E-93 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_21205 ba55321103982b09026b028cf35c95a9 380 PIRSF PIRSF038994 1 378 9.5E-116 T 01-11-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 Gene3D G3DSA:3.40.50.720 129 305 1.2E-140 T 01-11-2018 MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 Gene3D G3DSA:3.40.50.720 3 353 1.2E-140 T 01-11-2018 MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 PIRSF PIRSF000183 1 371 1.1E-191 T 01-11-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 SMART SM01003 4 136 1.4E-76 T 01-11-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 3.0E-180 T 01-11-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.9E-46 T 01-11-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 SMART SM01002 148 297 4.2E-90 T 01-11-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 01-11-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.8E-83 T 01-11-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 SUPERFAMILY SSF51735 136 303 2.05E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_03140 23da3934655a563067d93a1c7f9cac9f 377 SUPERFAMILY SSF52283 1 360 6.38E-67 T 01-11-2018 MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 339 2.9E-139 T 01-11-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 SUPERFAMILY SSF50129 12 139 4.11E-30 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 SMART SM00829 5 336 1.9E-11 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 Pfam PF13602 Zinc-binding dehydrogenase 196 336 9.9E-18 T 01-11-2018 MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 Gene3D G3DSA:3.90.180.10 26 335 1.7E-105 T 01-11-2018 MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 SUPERFAMILY SSF51735 117 288 2.45E-33 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 93 2.9E-6 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_17990 4274e7a2e205b02a8a614405882699a1 339 Gene3D G3DSA:3.40.50.720 128 277 1.7E-105 T 01-11-2018 MLA2C4_25935 213adcea54515aa70d52f99a5f24f914 270 Gene3D G3DSA:3.40.190.10 32 266 2.0E-95 T 01-11-2018 MLA2C4_25935 213adcea54515aa70d52f99a5f24f914 270 Gene3D G3DSA:3.40.190.10 111 219 2.0E-95 T 01-11-2018 MLA2C4_25935 213adcea54515aa70d52f99a5f24f914 270 SUPERFAMILY SSF53850 29 269 1.8E-78 T 01-11-2018 MLA2C4_25935 213adcea54515aa70d52f99a5f24f914 270 PIRSF PIRSF002854 1 270 1.9E-100 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_25935 213adcea54515aa70d52f99a5f24f914 270 Pfam PF03180 NLPA lipoprotein 30 268 2.0E-86 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_14500 67878eaa26b630a5eb098351e0486aea 321 Gene3D G3DSA:1.10.10.1320 11 54 1.5E-5 T 01-11-2018 MLA2C4_14500 67878eaa26b630a5eb098351e0486aea 321 Pfam PF13786 Domain of unknown function (DUF4179) 99 197 5.0E-9 T 01-11-2018 IPR025436 Domain of unknown function DUF4179 MLA2C4_14500 67878eaa26b630a5eb098351e0486aea 321 Pfam PF13490 Putative zinc-finger 10 36 3.8E-7 T 01-11-2018 IPR027383 Putative zinc-finger MLA2C4_00335 2b569c2f273bfead631d3deaa5385b2d 119 Pfam PF04977 Septum formation initiator 44 118 3.2E-18 T 01-11-2018 IPR007060 Septum formation initiator FtsL/DivIC MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 SMART SM00849 20 215 3.7E-26 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 Pfam PF00753 Metallo-beta-lactamase superfamily 20 166 1.0E-14 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 Gene3D G3DSA:3.60.15.10 12 444 1.8E-183 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 SUPERFAMILY SSF56281 9 426 2.41E-98 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 Gene3D G3DSA:3.40.50.10710 207 357 1.8E-183 T 01-11-2018 MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 409 1.8E-10 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 01-11-2018 IPR001587 Ribonuclease J, conserved site MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 555 3.2E-198 T 01-11-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 PIRSF PIRSF004803 1 557 2.0E-241 T 01-11-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 Hamap MF_01491 Ribonuclease J [rnj]. 3 557 46.658 T 01-11-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MLA2C4_08420 59e715332284718e8b42ae44e1fde74a 557 Gene3D G3DSA:3.10.20.580 451 557 2.5E-34 T 01-11-2018 MLA2C4_00185 e28bb68dba330de60aecdeb5b61e7ebf 208 Pfam PF02223 Thymidylate kinase 8 198 7.4E-50 T 01-11-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 MLA2C4_00185 e28bb68dba330de60aecdeb5b61e7ebf 208 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 30.651 T 01-11-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MLA2C4_00185 e28bb68dba330de60aecdeb5b61e7ebf 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 1.1E-59 T 01-11-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MLA2C4_00185 e28bb68dba330de60aecdeb5b61e7ebf 208 Gene3D G3DSA:3.40.50.300 1 207 3.0E-65 T 01-11-2018 MLA2C4_00185 e28bb68dba330de60aecdeb5b61e7ebf 208 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 01-11-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MLA2C4_00185 e28bb68dba330de60aecdeb5b61e7ebf 208 SUPERFAMILY SSF52540 1 206 3.49E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Pfam PF02272 DHHA1 domain 736 875 2.5E-30 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Gene3D G3DSA:3.30.980.10 565 700 7.0E-51 T 01-11-2018 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Gene3D G3DSA:3.10.310.40 768 877 4.8E-37 T 01-11-2018 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Pfam PF01411 tRNA synthetases class II (A) 8 558 4.0E-212 T 01-11-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Gene3D G3DSA:2.40.30.130 466 555 3.7E-10 T 01-11-2018 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 699 2.0E-16 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 SMART SM00863 656 699 8.1E-19 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Gene3D G3DSA:3.30.54.20 627 680 7.0E-51 T 01-11-2018 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Gene3D G3DSA:3.30.930.10 4 242 2.4E-94 T 01-11-2018 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 SUPERFAMILY SSF50447 457 555 7.77E-17 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 184.783 T 01-11-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 SUPERFAMILY SSF101353 246 439 3.4E-68 T 01-11-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 858 0.0 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 SUPERFAMILY SSF55186 555 720 5.23E-51 T 01-11-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 SUPERFAMILY SSF55681 5 245 1.32E-88 T 01-11-2018 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 8.8E-32 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 8.8E-32 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 301 314 8.8E-32 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 8.8E-32 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MLA2C4_22890 1af35b899dbed374ca45e629f40f5d5a 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 277 293 8.8E-32 T 01-11-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 SUPERFAMILY SSF51905 3 316 4.24E-46 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 294 9.3E-64 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.9E-26 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 5.9E-26 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 5.9E-26 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 5.9E-26 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 5.9E-26 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 430 6.7E-15 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 Gene3D G3DSA:3.50.50.60 114 440 6.5E-162 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 SUPERFAMILY SSF55424 323 443 5.84E-34 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 9.8E-19 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 9.8E-19 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 9.8E-19 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 402 9.8E-19 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 9.8E-19 T 01-11-2018 MLA2C4_06555 b52471510b2ce0e959a6eeaf7cc9c3f0 444 Gene3D G3DSA:3.50.50.60 3 340 6.5E-162 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 SUPERFAMILY SSF51726 5 391 1.57E-99 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 Gene3D G3DSA:3.20.20.210 7 523 0.0 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 Gene3D G3DSA:3.20.20.210 388 755 0.0 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 PIRSF PIRSF000382 2 762 0.0 T 01-11-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 757 34.483 T 01-11-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 313 5.1E-122 T 01-11-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 756 0.0 T 01-11-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 SUPERFAMILY SSF51726 395 754 7.06E-110 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MLA2C4_20930 22fbb57e1f32fbe43ea2e61c7f982e35 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 4.0E-149 T 01-11-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 SUPERFAMILY SSF103473 26 414 6.54E-51 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 Pfam PF07690 Major Facilitator Superfamily 30 367 3.4E-38 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 2.0E-8 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 185 202 2.0E-8 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 29 51 2.0E-8 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 388 411 2.0E-8 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 158 179 2.0E-8 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_09240 71a4d44e55adcfb240205ad9e7091daa 420 Gene3D G3DSA:1.20.1250.20 25 413 4.7E-45 T 01-11-2018 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 Gene3D G3DSA:3.40.50.1820 2 279 7.4E-36 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00412 Epoxide hydrolase signature 257 279 1.8E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00412 Epoxide hydrolase signature 40 55 1.8E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.8E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00412 Epoxide hydrolase signature 85 98 1.8E-5 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 Pfam PF00561 alpha/beta hydrolase fold 16 130 4.4E-15 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 SUPERFAMILY SSF53474 3 277 1.77E-33 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 5.3E-7 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 5.3E-7 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 5.3E-7 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_08905 505b4eaccbc1ad79b6a99dc09a466896 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 5.3E-7 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_26975 ec1d12e1feaf999a7834a8ac571f1dcd 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 431 7.3E-177 T 01-11-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 MLA2C4_26975 ec1d12e1feaf999a7834a8ac571f1dcd 433 PIRSF PIRSF006351 1 433 1.5E-150 T 01-11-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_26975 ec1d12e1feaf999a7834a8ac571f1dcd 433 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 9 431 7.3E-177 T 01-11-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_26975 ec1d12e1feaf999a7834a8ac571f1dcd 433 Pfam PF02378 Phosphotransferase system, EIIC 26 356 3.3E-71 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_12475 282f6656aac3118f2f17c86cd68cf6ba 253 SUPERFAMILY SSF52768 27 224 3.24E-24 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily MLA2C4_12475 282f6656aac3118f2f17c86cd68cf6ba 253 Pfam PF00491 Arginase family 20 218 8.6E-13 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_12475 282f6656aac3118f2f17c86cd68cf6ba 253 PIRSF PIRSF036979 11 226 1.3E-10 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_12475 282f6656aac3118f2f17c86cd68cf6ba 253 Gene3D G3DSA:3.40.800.10 3 229 3.8E-14 T 01-11-2018 MLA2C4_21475 b9ab32ea888bcb05b36c8a616252ae96 439 Pfam PF03553 Na+/H+ antiporter family 151 433 5.4E-69 T 01-11-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MLA2C4_21475 b9ab32ea888bcb05b36c8a616252ae96 439 PRINTS PR00173 Glutamate-aspartate symporter signature 372 391 9.5E-5 T 01-11-2018 MLA2C4_21475 b9ab32ea888bcb05b36c8a616252ae96 439 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 9.5E-5 T 01-11-2018 MLA2C4_21475 b9ab32ea888bcb05b36c8a616252ae96 439 Pfam PF13726 Na+-H+ antiporter family 2 88 3.7E-33 T 01-11-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 Gene3D G3DSA:1.20.1250.20 258 479 1.1E-19 T 01-11-2018 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 Gene3D G3DSA:1.20.1720.10 5 215 1.5E-57 T 01-11-2018 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 SUPERFAMILY SSF103473 2 472 4.19E-71 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 8 32 3.2E-6 T 01-11-2018 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 3.2E-6 T 01-11-2018 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 67 89 3.2E-6 T 01-11-2018 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 3.2E-6 T 01-11-2018 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 414 3.8E-69 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_24490 c1f3645c21f920d6ff4502e2ae533ed6 479 Pfam PF07690 Major Facilitator Superfamily 9 402 7.0E-60 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_04580 312eb2415b352214c53ba08426d71c71 112 SUPERFAMILY SSF46785 13 109 3.94E-34 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_04580 312eb2415b352214c53ba08426d71c71 112 Gene3D G3DSA:1.10.10.10 14 111 5.5E-38 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04580 312eb2415b352214c53ba08426d71c71 112 Pfam PF01638 HxlR-like helix-turn-helix 26 109 6.1E-28 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_09905 50f77ae795612331731c49c4a87810ba 317 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 61 296 5.6E-67 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_09905 50f77ae795612331731c49c4a87810ba 317 SUPERFAMILY SSF56601 8 313 4.68E-68 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_09905 50f77ae795612331731c49c4a87810ba 317 Gene3D G3DSA:3.40.710.10 40 314 3.1E-84 T 01-11-2018 MLA2C4_09905 50f77ae795612331731c49c4a87810ba 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 171 184 9.5E-15 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_09905 50f77ae795612331731c49c4a87810ba 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 91 102 9.5E-15 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_09905 50f77ae795612331731c49c4a87810ba 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 161 9.5E-15 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_05565 eb79daadfc10f214142c0db746dd1e03 111 ProDom PD073069 YHAI 3D-STRUCTURE 11 100 4.0E-44 T 01-11-2018 IPR015058 Protein of unknown function DUF1878 MLA2C4_05565 eb79daadfc10f214142c0db746dd1e03 111 Gene3D G3DSA:1.10.3750.10 1 111 2.9E-34 T 01-11-2018 IPR035945 YhaI-like superfamily MLA2C4_05565 eb79daadfc10f214142c0db746dd1e03 111 Pfam PF08963 Protein of unknown function (DUF1878) 2 108 1.6E-42 T 01-11-2018 IPR015058 Protein of unknown function DUF1878 MLA2C4_05565 eb79daadfc10f214142c0db746dd1e03 111 SUPERFAMILY SSF109915 1 110 1.03E-47 T 01-11-2018 IPR035945 YhaI-like superfamily MLA2C4_02030 412d226f80e22b3919f7badfda5b5689 187 SUPERFAMILY SSF52833 1 187 9.78E-55 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_02030 412d226f80e22b3919f7badfda5b5689 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 2.7E-105 T 01-11-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MLA2C4_02030 412d226f80e22b3919f7badfda5b5689 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 7.1E-5 T 01-11-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_02030 412d226f80e22b3919f7badfda5b5689 187 PIRSF PIRSF000239 1 187 1.5E-49 T 01-11-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_02030 412d226f80e22b3919f7badfda5b5689 187 Gene3D G3DSA:3.40.30.10 1 186 2.0E-59 T 01-11-2018 MLA2C4_02030 412d226f80e22b3919f7badfda5b5689 187 Pfam PF00578 AhpC/TSA family 4 133 3.6E-32 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_22665 976a9d55217c4cfea7af25be283886ba 499 Pfam PF16244 Domain of unknown function (DUF4901) 11 239 5.8E-104 T 01-11-2018 IPR032599 Protein of unknown function DUF4901 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 SMART SM00642 33 421 2.6E-69 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 SUPERFAMILY SSF51445 34 412 1.7E-103 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 PIRSF PIRSF001021 7 513 4.0E-234 T 01-11-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 Pfam PF00128 Alpha amylase, catalytic domain 64 402 3.2E-24 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 Gene3D G3DSA:3.20.20.80 34 398 6.0E-166 T 01-11-2018 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 Gene3D G3DSA:2.60.40.1180 427 513 8.1E-35 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 Pfam PF09154 Domain of unknown function (DUF1939) 465 510 5.2E-7 T 01-11-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 Gene3D G3DSA:2.40.30.140 132 235 6.0E-166 T 01-11-2018 MLA2C4_18140 b6c48f277a72539f1f2aee3b1794f821 513 SUPERFAMILY SSF51011 424 513 5.61E-35 T 01-11-2018 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 PIRSF PIRSF000804 1 376 2.3E-94 T 01-11-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 Gene3D G3DSA:3.10.150.10 1 247 1.2E-109 T 01-11-2018 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 Gene3D G3DSA:3.70.10.10 144 373 1.2E-109 T 01-11-2018 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 SMART SM00480 17 371 1.8E-106 T 01-11-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 SUPERFAMILY SSF55979 251 374 8.59E-23 T 01-11-2018 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 1.3E-90 T 01-11-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 SUPERFAMILY SSF55979 131 248 2.03E-28 T 01-11-2018 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 135 248 4.8E-33 T 01-11-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 SUPERFAMILY SSF55979 1 126 3.64E-22 T 01-11-2018 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 374 7.6E-25 T 01-11-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MLA2C4_14285 a4a507ea7708124349812f7e1b237597 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 126 8.8E-26 T 01-11-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 01-11-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PIRSF PIRSF000724 1 394 2.2E-159 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 SUPERFAMILY SSF53748 1 393 9.3E-164 T 01-11-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 3.8E-97 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.086 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 Gene3D G3DSA:3.40.50.1260 177 381 2.3E-88 T 01-11-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 Pfam PF00162 Phosphoglycerate kinase 6 383 2.2E-166 T 01-11-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26580 3bfd1e77f9b79409a843f053668967d2 394 Gene3D G3DSA:3.40.50.1260 1 170 2.6E-76 T 01-11-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 PRINTS PR00116 Arginase signature 254 268 2.5E-40 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 PRINTS PR00116 Arginase signature 117 144 2.5E-40 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 PRINTS PR00116 Arginase signature 94 109 2.5E-40 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 PRINTS PR00116 Arginase signature 219 248 2.5E-40 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 PRINTS PR00116 Arginase signature 171 189 2.5E-40 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 PIRSF PIRSF036979 1 294 3.0E-40 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 Gene3D G3DSA:3.40.800.10 2 297 4.4E-114 T 01-11-2018 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 SUPERFAMILY SSF52768 4 293 5.22E-93 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 TIGRFAM TIGR01229 rocF_arginase: arginase 6 296 3.1E-105 T 01-11-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 ProSitePatterns PS01053 Arginase family signature. 222 243 - T 01-11-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MLA2C4_00950 725629eee6fa2982132a303323b764bf 297 Pfam PF00491 Arginase family 4 292 1.2E-79 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_26495 9c30dff6b3c0a83081c090accb7da96f 338 SUPERFAMILY SSF81345 17 330 1.16E-65 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_26495 9c30dff6b3c0a83081c090accb7da96f 338 Gene3D G3DSA:1.10.3470.10 16 333 4.7E-62 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_26495 9c30dff6b3c0a83081c090accb7da96f 338 Pfam PF01032 FecCD transport family 36 330 3.2E-65 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 Pfam PF02872 5'-nucleotidase, C-terminal domain 284 421 3.5E-13 T 01-11-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 Gene3D G3DSA:3.60.21.10 1 273 6.2E-47 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 SUPERFAMILY SSF55816 282 456 1.29E-24 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 Pfam PF00149 Calcineurin-like phosphoesterase 3 200 1.0E-7 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 SUPERFAMILY SSF56300 1 247 9.22E-56 T 01-11-2018 MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 Gene3D G3DSA:3.90.780.10 277 461 9.6E-13 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_25895 7952c657c3eea24cad977a281ebb91b6 463 PIRSF PIRSF036361 1 459 8.6E-161 T 01-11-2018 IPR011240 Phosphoesterase-related protein YunD MLA2C4_03260 3990ca7fadff9a33cbcc0cb533d58e63 243 Pfam PF13649 Methyltransferase domain 49 140 5.8E-13 T 01-11-2018 MLA2C4_03260 3990ca7fadff9a33cbcc0cb533d58e63 243 SUPERFAMILY SSF53335 17 243 7.11E-34 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_03260 3990ca7fadff9a33cbcc0cb533d58e63 243 Gene3D G3DSA:3.40.50.150 31 243 4.1E-53 T 01-11-2018 MLA2C4_13770 95176c3f89ba8117574f8d0eaa4896c5 210 Pfam PF08241 Methyltransferase domain 40 133 3.7E-18 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_13770 95176c3f89ba8117574f8d0eaa4896c5 210 SUPERFAMILY SSF53335 2 192 7.45E-35 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_13770 95176c3f89ba8117574f8d0eaa4896c5 210 Gene3D G3DSA:3.40.50.150 22 208 7.6E-30 T 01-11-2018 MLA2C4_03275 e3469afe38f4c515b92a00de57cf2bfb 140 SUPERFAMILY SSF55811 6 116 9.07E-28 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_03275 e3469afe38f4c515b92a00de57cf2bfb 140 Pfam PF00293 NUDIX domain 5 114 3.1E-20 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_03275 e3469afe38f4c515b92a00de57cf2bfb 140 Gene3D G3DSA:3.90.79.10 2 128 1.1E-28 T 01-11-2018 MLA2C4_03275 e3469afe38f4c515b92a00de57cf2bfb 140 PRINTS PR00502 NUDIX hydrolase family signature 30 44 6.6E-9 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_03275 e3469afe38f4c515b92a00de57cf2bfb 140 PRINTS PR00502 NUDIX hydrolase family signature 44 59 6.6E-9 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_03275 e3469afe38f4c515b92a00de57cf2bfb 140 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_05360 845c218d6f3057aef1bed45b85d493c9 103 Pfam PF01906 Putative heavy-metal-binding 1 103 6.2E-38 T 01-11-2018 IPR002765 Uncharacterised protein family UPF0145 MLA2C4_05360 845c218d6f3057aef1bed45b85d493c9 103 Gene3D G3DSA:3.30.110.70 1 103 6.3E-44 T 01-11-2018 MLA2C4_05360 845c218d6f3057aef1bed45b85d493c9 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.629 T 01-11-2018 IPR002765 Uncharacterised protein family UPF0145 MLA2C4_05360 845c218d6f3057aef1bed45b85d493c9 103 SUPERFAMILY SSF117782 1 103 1.28E-36 T 01-11-2018 IPR035439 UPF0145 domain superfamily MLA2C4_02695 d86aec1ac7eedd8b6bd45289cb61032d 52 Pfam PF08176 Small acid-soluble spore protein K family 1 48 6.4E-25 T 01-11-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 MLA2C4_02695 d86aec1ac7eedd8b6bd45289cb61032d 52 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 50 16.381 T 01-11-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 MLA2C4_02695 d86aec1ac7eedd8b6bd45289cb61032d 52 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 17 48 1.9E-22 T 01-11-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 SUPERFAMILY SSF47384 259 343 5.89E-18 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 SUPERFAMILY SSF55874 348 498 5.89E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 Gene3D G3DSA:3.30.565.10 347 499 3.1E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 Gene3D G3DSA:1.20.1480.50 198 271 3.3E-8 T 01-11-2018 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 341 2.3E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 SMART SM00388 276 343 2.8E-16 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 1.1E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 1.1E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 SUPERFAMILY SSF158472 221 266 2.09E-6 T 01-11-2018 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 SMART SM00304 216 268 3.9E-7 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 SMART SM00387 389 500 1.3E-25 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 Gene3D G3DSA:1.10.287.130 272 343 1.9E-20 T 01-11-2018 MLA2C4_01605 aa0a3d3dcca180dd1d24500a5381ac7b 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 390 497 1.8E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_26490 d196d4531ba3b2ec814b159ce1a69ce9 354 Gene3D G3DSA:1.10.3470.10 34 353 5.6E-49 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_26490 d196d4531ba3b2ec814b159ce1a69ce9 354 Pfam PF01032 FecCD transport family 69 350 4.5E-42 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_26490 d196d4531ba3b2ec814b159ce1a69ce9 354 SUPERFAMILY SSF81345 30 350 2.35E-54 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_23165 f1f7182d9219f726be3e1feb102e90e3 114 Pfam PF04327 Cysteine protease Prp 1 105 2.6E-25 T 01-11-2018 IPR007422 Cysteine protease Prp MLA2C4_23165 f1f7182d9219f726be3e1feb102e90e3 114 Gene3D G3DSA:3.30.70.1490 1 112 2.4E-33 T 01-11-2018 IPR036764 Cysteine protease Prp superfamily MLA2C4_23165 f1f7182d9219f726be3e1feb102e90e3 114 SUPERFAMILY SSF118010 1 110 2.62E-30 T 01-11-2018 IPR036764 Cysteine protease Prp superfamily MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 496 5.9E-137 T 01-11-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 Pfam PF00361 Proton-conducting membrane transporter 139 437 5.7E-67 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 3.7E-34 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 3.7E-34 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 3.7E-34 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 3.7E-34 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27390 c48a0bf477b144aebbec44467612df09 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 3.7E-34 T 01-11-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_26400 a4c6159ff91927505198d3443c07135b 500 Pfam PF13295 Domain of unknown function (DUF4077) 2 173 4.7E-85 T 01-11-2018 IPR025278 Domain of unknown function DUF4077 MLA2C4_26400 a4c6159ff91927505198d3443c07135b 500 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 298 455 2.4E-30 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26400 a4c6159ff91927505198d3443c07135b 500 SMART SM00283 227 485 4.3E-33 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26400 a4c6159ff91927505198d3443c07135b 500 Gene3D G3DSA:1.10.287.950 179 500 1.4E-48 T 01-11-2018 MLA2C4_26400 a4c6159ff91927505198d3443c07135b 500 SUPERFAMILY SSF58104 206 496 1.26E-52 T 01-11-2018 MLA2C4_13345 1b4c2d02023d9fadc94ae89733bb8230 588 SUPERFAMILY SSF56519 34 216 1.09E-29 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_13345 1b4c2d02023d9fadc94ae89733bb8230 588 Pfam PF03717 Penicillin-binding Protein dimerisation domain 39 205 1.0E-29 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_13345 1b4c2d02023d9fadc94ae89733bb8230 588 Gene3D G3DSA:3.90.1310.30 32 213 5.8E-30 T 01-11-2018 MLA2C4_13345 1b4c2d02023d9fadc94ae89733bb8230 588 Gene3D G3DSA:3.40.710.10 214 583 1.3E-69 T 01-11-2018 MLA2C4_13345 1b4c2d02023d9fadc94ae89733bb8230 588 SUPERFAMILY SSF56601 171 574 3.3E-58 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13345 1b4c2d02023d9fadc94ae89733bb8230 588 Pfam PF00905 Penicillin binding protein transpeptidase domain 243 569 2.0E-45 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_21785 b6f06d25bd659799516223292aaa8611 299 PIRSF PIRSF000428 1 299 6.0E-83 T 01-11-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_21785 b6f06d25bd659799516223292aaa8611 299 SUPERFAMILY SSF53659 4 297 3.93E-62 T 01-11-2018 MLA2C4_21785 b6f06d25bd659799516223292aaa8611 299 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 3 296 8.1E-130 T 01-11-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 MLA2C4_21785 b6f06d25bd659799516223292aaa8611 299 Pfam PF01515 Phosphate acetyl/butaryl transferase 80 294 2.4E-51 T 01-11-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_21785 b6f06d25bd659799516223292aaa8611 299 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 79 3.0E-5 T 01-11-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_21785 b6f06d25bd659799516223292aaa8611 299 Gene3D G3DSA:3.40.718.10 2 299 7.7E-107 T 01-11-2018 MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 3.8E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 SMART SM00862 148 221 5.2E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 Pfam PF00072 Response regulator receiver domain 3 111 9.2E-31 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 SUPERFAMILY SSF52172 1 170 6.83E-41 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 Gene3D G3DSA:1.10.10.10 127 223 1.2E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 Gene3D G3DSA:3.40.50.2300 1 126 5.7E-38 T 01-11-2018 MLA2C4_27205 8eaceb8e0a39418bcaa3e0387fafb4be 223 SMART SM00448 1 111 4.8E-45 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 Gene3D G3DSA:3.30.465.10 348 439 4.6E-19 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 Pfam PF03471 Transporter associated domain 356 429 2.6E-18 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 Pfam PF00571 CBS domain 288 338 5.1E-7 T 01-11-2018 IPR000644 CBS domain MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 Gene3D G3DSA:3.10.580.10 195 347 1.0E-50 T 01-11-2018 MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 SUPERFAMILY SSF56176 352 437 5.18E-19 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 SMART SM01091 354 431 7.8E-22 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 Pfam PF01595 Domain of unknown function DUF21 9 201 5.5E-50 T 01-11-2018 IPR002550 CNNM, transmembrane domain MLA2C4_17655 f092440b55448c525e0896180e14ff9e 442 SUPERFAMILY SSF54631 204 341 1.52E-30 T 01-11-2018 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 Gene3D G3DSA:2.40.110.10 120 233 1.5E-45 T 01-11-2018 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 SUPERFAMILY SSF56645 1 239 2.62E-86 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 6.7E-55 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 3.3E-26 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 5.5E-38 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 PIRSF PIRSF016578 6 366 6.7E-22 T 01-11-2018 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 Gene3D G3DSA:1.10.540.10 1 118 2.8E-44 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 Gene3D G3DSA:1.20.140.10 234 376 7.6E-59 T 01-11-2018 MLA2C4_27660 66614d6ac42525be19d9f91ae0c020c4 376 SUPERFAMILY SSF47203 226 376 4.99E-62 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 Gene3D G3DSA:1.10.260.40 3 58 9.5E-23 T 01-11-2018 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 01-11-2018 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 SUPERFAMILY SSF47413 2 59 3.62E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 SMART SM00354 1 71 2.4E-26 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 SUPERFAMILY SSF53822 58 286 9.64E-35 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 Gene3D G3DSA:3.40.50.2300 62 281 3.1E-36 T 01-11-2018 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 Pfam PF13377 Periplasmic binding protein-like domain 154 281 1.2E-8 T 01-11-2018 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.0E-20 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.8E-7 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.8E-7 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_21480 6448ff3f9408fe36821a6d0c5656defa 287 Gene3D G3DSA:3.40.50.2300 142 267 3.1E-36 T 01-11-2018 MLA2C4_22590 05c384b9122c5917843b692841131e9a 185 Gene3D G3DSA:3.40.140.10 2 146 1.6E-46 T 01-11-2018 MLA2C4_22590 05c384b9122c5917843b692841131e9a 185 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_22590 05c384b9122c5917843b692841131e9a 185 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 151 6.5E-91 T 01-11-2018 IPR013404 Competence operon E, ComEB MLA2C4_22590 05c384b9122c5917843b692841131e9a 185 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.1E-28 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MLA2C4_22590 05c384b9122c5917843b692841131e9a 185 SUPERFAMILY SSF53927 7 143 1.77E-40 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_22590 05c384b9122c5917843b692841131e9a 185 PIRSF PIRSF006019 1 151 1.4E-58 T 01-11-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 Pfam PF00571 CBS domain 294 329 0.0064 T 01-11-2018 IPR000644 CBS domain MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 Pfam PF00571 CBS domain 337 390 1.4E-4 T 01-11-2018 IPR000644 CBS domain MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 394 1.2E-151 T 01-11-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 SUPERFAMILY SSF52540 44 271 1.05E-76 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 SMART SM00382 54 243 5.3E-19 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 SUPERFAMILY SSF54631 282 397 6.82E-21 T 01-11-2018 MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 Gene3D G3DSA:3.40.50.300 32 287 4.2E-77 T 01-11-2018 MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 SMART SM00116 283 331 0.33 T 01-11-2018 IPR000644 CBS domain MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 SMART SM00116 343 390 0.0032 T 01-11-2018 IPR000644 CBS domain MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 Pfam PF00005 ABC transporter 46 193 1.4E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_14760 b9d63418a5ff7d0ee3d8ca46dbd57e40 401 Gene3D G3DSA:3.10.580.10 288 396 9.6E-14 T 01-11-2018 MLA2C4_01790 d76a3f21918216c7eb99bc2ff95e085a 195 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 32.311 T 01-11-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MLA2C4_01790 d76a3f21918216c7eb99bc2ff95e085a 195 Gene3D G3DSA:3.40.50.170 1 195 1.6E-75 T 01-11-2018 MLA2C4_01790 d76a3f21918216c7eb99bc2ff95e085a 195 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 01-11-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_01790 d76a3f21918216c7eb99bc2ff95e085a 195 SUPERFAMILY SSF53328 3 187 3.4E-62 T 01-11-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_01790 d76a3f21918216c7eb99bc2ff95e085a 195 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 188 5.5E-73 T 01-11-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MLA2C4_01790 d76a3f21918216c7eb99bc2ff95e085a 195 Pfam PF00551 Formyl transferase 3 182 1.2E-61 T 01-11-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MLA2C4_26475 624607654913213e220e7f9931ed08a7 426 Pfam PF00860 Permease family 12 392 4.3E-66 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_17465 8f33c007958889078b8f15134217affd 552 Pfam PF16949 Putative ATP-binding cassette 69 449 7.0E-15 T 01-11-2018 IPR031599 Putative ATP-binding cassette MLA2C4_25790 b1e9f3f8dc223c08143f047d4bc7d034 262 Pfam PF00005 ABC transporter 23 171 2.1E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_25790 b1e9f3f8dc223c08143f047d4bc7d034 262 SMART SM00382 32 220 6.4E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25790 b1e9f3f8dc223c08143f047d4bc7d034 262 SUPERFAMILY SSF52540 3 226 1.46E-71 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25790 b1e9f3f8dc223c08143f047d4bc7d034 262 Gene3D G3DSA:3.40.50.300 1 254 7.2E-69 T 01-11-2018 MLA2C4_25790 b1e9f3f8dc223c08143f047d4bc7d034 262 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 Pfam PF11563 Protoglobin 32 186 2.8E-38 T 01-11-2018 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 209 238 2.7E-5 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 322 351 2.7E-5 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 SUPERFAMILY SSF58104 145 425 1.7E-50 T 01-11-2018 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 240 421 2.0E-35 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 Gene3D G3DSA:1.10.287.950 176 432 1.1E-48 T 01-11-2018 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 SUPERFAMILY SSF46458 15 178 1.68E-36 T 01-11-2018 IPR009050 Globin-like superfamily MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 Gene3D G3DSA:1.10.490.10 24 175 1.4E-36 T 01-11-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MLA2C4_28100 7c904c931aae0511c94228ff5bda99c2 433 SMART SM00283 195 428 2.2E-22 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 Pfam PF03705 CheR methyltransferase, all-alpha domain 21 70 7.8E-12 T 01-11-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 SUPERFAMILY SSF53335 85 268 3.39E-42 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 SMART SM00138 19 282 1.9E-37 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 PRINTS PR00996 Glutamate methyltransferase family signature 78 90 6.4E-25 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 6.4E-25 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 6.4E-25 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 PRINTS PR00996 Glutamate methyltransferase family signature 41 54 6.4E-25 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 PRINTS PR00996 Glutamate methyltransferase family signature 146 162 6.4E-25 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 PRINTS PR00996 Glutamate methyltransferase family signature 114 134 6.4E-25 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 SUPERFAMILY SSF47757 13 87 9.81E-9 T 01-11-2018 MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 Pfam PF01739 CheR methyltransferase, SAM binding domain 85 263 5.2E-40 T 01-11-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MLA2C4_05335 5f4ff2d81e44ba19ad46a4a6356ad0e3 285 Gene3D G3DSA:3.40.50.150 84 284 4.2E-57 T 01-11-2018 MLA2C4_11915 5a45b4dd3db6e462a281bdd911a9610c 267 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 223 266 7.0E-19 T 01-11-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase MetaCyc: PWY-7883 MLA2C4_11915 5a45b4dd3db6e462a281bdd911a9610c 267 Gene3D G3DSA:3.20.20.80 2 189 6.4E-72 T 01-11-2018 MLA2C4_11915 5a45b4dd3db6e462a281bdd911a9610c 267 Pfam PF01183 Glycosyl hydrolases family 25 6 169 3.1E-24 T 01-11-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 MLA2C4_11915 5a45b4dd3db6e462a281bdd911a9610c 267 Gene3D G3DSA:3.30.70.2030 190 267 8.6E-34 T 01-11-2018 MLA2C4_11915 5a45b4dd3db6e462a281bdd911a9610c 267 SUPERFAMILY SSF51445 5 186 3.0E-42 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 44.764 T 01-11-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 493 5.4E-215 T 01-11-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 01-11-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 Pfam PF00221 Aromatic amino acid lyase 9 466 8.4E-196 T 01-11-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 Gene3D G3DSA:1.20.200.10 196 500 3.2E-123 T 01-11-2018 MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 Gene3D G3DSA:1.10.275.10 1 195 1.2E-68 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_18975 20c12c1267797f0d0adc22251bbc898c 505 SUPERFAMILY SSF48557 1 493 2.59E-194 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_28020 cf0feab1c160cdc7baea107613b80dd2 231 SUPERFAMILY SSF56784 3 229 1.43E-44 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_28020 cf0feab1c160cdc7baea107613b80dd2 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 94 194 4.3E-12 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_28020 cf0feab1c160cdc7baea107613b80dd2 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 1.3E-23 T 01-11-2018 MLA2C4_28020 cf0feab1c160cdc7baea107613b80dd2 231 Gene3D G3DSA:1.10.150.240 17 100 2.8E-77 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_28020 cf0feab1c160cdc7baea107613b80dd2 231 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 226 8.1E-84 T 01-11-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 MLA2C4_28020 cf0feab1c160cdc7baea107613b80dd2 231 Gene3D G3DSA:3.40.50.1000 6 223 2.8E-77 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_18945 f54479e5a2a5a28ae33c51beccad6a77 522 PIRSF PIRSF006429 1 522 3.6E-151 T 01-11-2018 IPR024188 Glutamate synthase large subunit-like protein MLA2C4_18945 f54479e5a2a5a28ae33c51beccad6a77 522 Pfam PF01645 Conserved region in glutamate synthase 140 491 1.6E-77 T 01-11-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MLA2C4_18945 f54479e5a2a5a28ae33c51beccad6a77 522 SUPERFAMILY SSF51395 7 518 3.61E-92 T 01-11-2018 MLA2C4_18945 f54479e5a2a5a28ae33c51beccad6a77 522 Gene3D G3DSA:3.20.20.70 129 518 3.5E-85 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_18945 f54479e5a2a5a28ae33c51beccad6a77 522 PIRSF PIRSF500060 1 522 4.9E-203 T 01-11-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 311 7.0E-112 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 Gene3D G3DSA:3.30.420.40 132 298 1.9E-126 T 01-11-2018 MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 2.4E-50 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.4E-50 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 2.4E-50 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.4E-50 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.4E-50 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 2.4E-50 T 01-11-2018 IPR017861 Kae1/TsaD family MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 SUPERFAMILY SSF53067 105 313 3.76E-46 T 01-11-2018 MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 336 66.559 T 01-11-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 Pfam PF00814 Glycoprotease family 27 311 2.0E-108 T 01-11-2018 IPR000905 Gcp-like domain MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 1.1E-136 T 01-11-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 SUPERFAMILY SSF53067 6 126 3.3E-33 T 01-11-2018 MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 01-11-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 MLA2C4_01545 7368d8777fd4f52a7f4f6004f1d31cb6 338 Gene3D G3DSA:3.30.420.40 7 320 1.9E-126 T 01-11-2018 MLA2C4_10110 0eb2e0fa7c165f6a7bf33d931d6fc2e2 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_10110 0eb2e0fa7c165f6a7bf33d931d6fc2e2 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_10110 0eb2e0fa7c165f6a7bf33d931d6fc2e2 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 9 62 1.6E-21 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_10110 0eb2e0fa7c165f6a7bf33d931d6fc2e2 68 Gene3D G3DSA:1.10.8.910 8 67 4.9E-30 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_05840 a42f77f162e53e61676760ef49bb6c46 325 Pfam PF01966 HD domain 49 116 1.6E-8 T 01-11-2018 IPR006674 HD domain MLA2C4_05840 a42f77f162e53e61676760ef49bb6c46 325 SUPERFAMILY SSF109604 3 259 3.14E-46 T 01-11-2018 MLA2C4_05840 a42f77f162e53e61676760ef49bb6c46 325 SMART SM00471 45 159 3.7E-7 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_05840 a42f77f162e53e61676760ef49bb6c46 325 Gene3D G3DSA:1.10.3210.10 2 256 4.4E-42 T 01-11-2018 MLA2C4_16315 24b68915fda3b91c5efdd6738f55f71f 285 SUPERFAMILY SSF56281 26 254 1.02E-41 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_16315 24b68915fda3b91c5efdd6738f55f71f 285 Gene3D G3DSA:3.60.15.10 16 270 1.4E-37 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_16315 24b68915fda3b91c5efdd6738f55f71f 285 SMART SM00849 38 248 3.5E-33 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_16315 24b68915fda3b91c5efdd6738f55f71f 285 Pfam PF00753 Metallo-beta-lactamase superfamily 38 248 1.2E-32 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Gene3D G3DSA:3.10.196.10 880 1131 2.7E-56 T 01-11-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 SMART SM01018 618 701 8.7E-38 T 01-11-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 906 1131 4.7E-51 T 01-11-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Pfam PF00809 Pterin binding enzyme 334 567 2.3E-40 T 01-11-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Gene3D G3DSA:3.20.20.330 1 314 5.5E-111 T 01-11-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Pfam PF02310 B12 binding domain 707 796 2.4E-21 T 01-11-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 TIGRFAM TIGR02082 metH: methionine synthase 8 1131 0.0 T 01-11-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 SUPERFAMILY SSF47644 617 700 1.44E-23 T 01-11-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 SUPERFAMILY SSF51717 331 597 5.76E-80 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Gene3D G3DSA:1.10.288.10 885 941 2.7E-56 T 01-11-2018 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Pfam PF02574 Homocysteine S-methyltransferase 13 299 7.5E-77 T 01-11-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Gene3D G3DSA:1.10.1240.10 610 698 1.7E-26 T 01-11-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Gene3D G3DSA:3.40.50.280 703 853 5.6E-47 T 01-11-2018 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Pfam PF02607 B12 binding domain 621 694 3.5E-22 T 01-11-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 SUPERFAMILY SSF82282 2 373 1.96E-111 T 01-11-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 SUPERFAMILY SSF56507 866 1131 2.49E-82 T 01-11-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 Gene3D G3DSA:3.20.20.20 315 609 2.5E-106 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 PIRSF PIRSF000381 1 1132 0.0 T 01-11-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22240 af3c1b8baa83cfaf09c8cb0af814ff42 1132 SUPERFAMILY SSF52242 702 847 4.71E-39 T 01-11-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 SUPERFAMILY SSF158911 44 163 1.57E-30 T 01-11-2018 IPR037250 NEAT domain superfamily MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 SMART SM00725 42 166 1.9E-20 T 01-11-2018 IPR006635 NEAT domain MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 Pfam PF00395 S-layer homology domain 290 330 1.4E-6 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 Pfam PF00395 S-layer homology domain 227 269 2.7E-12 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 Pfam PF00395 S-layer homology domain 169 209 1.7E-8 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 Gene3D G3DSA:2.60.40.1850 36 163 4.0E-36 T 01-11-2018 MLA2C4_05820 059ad02c48bd40f2338d6bd2281826b4 341 Pfam PF05031 Iron Transport-associated domain 41 159 6.1E-30 T 01-11-2018 IPR006635 NEAT domain MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 PIRSF PIRSF000524 1 363 1.9E-53 T 01-11-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 3 363 7.8E-200 T 01-11-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 365 202.604 T 01-11-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 Gene3D G3DSA:3.40.640.10 17 263 2.3E-113 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 SUPERFAMILY SSF53383 4 360 1.66E-85 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 7 359 1.6E-153 T 01-11-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 Gene3D G3DSA:3.90.1150.10 9 353 2.3E-113 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_07040 b4ff15426eeed723d95909ee151c35e9 365 Pfam PF00266 Aminotransferase class-V 33 305 9.9E-28 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_07555 f560eb9643134fb577fed70b9c104c1a 451 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 1.6E-24 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_07555 f560eb9643134fb577fed70b9c104c1a 451 Pfam PF00209 Sodium:neurotransmitter symporter family 149 446 4.8E-29 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_07555 f560eb9643134fb577fed70b9c104c1a 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 7.8E-11 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_07555 f560eb9643134fb577fed70b9c104c1a 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 297 316 7.8E-11 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_07555 f560eb9643134fb577fed70b9c104c1a 451 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 7.8E-11 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_07555 f560eb9643134fb577fed70b9c104c1a 451 SUPERFAMILY SSF161070 6 444 2.22E-129 T 01-11-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MLA2C4_21230 d91235549e8ed06e4c6212e7b7b79bed 31 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 28 3.2E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_21230 d91235549e8ed06e4c6212e7b7b79bed 31 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 7 30 1.4E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_01010 6852a028cc7de785d51f601609727715 258 Gene3D G3DSA:3.40.50.720 2 258 2.3E-65 T 01-11-2018 MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 8.4E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 8.4E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 8.4E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 8.4E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.4E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 8.4E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 SUPERFAMILY SSF51735 6 256 1.38E-62 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 2.6E-6 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 2.6E-6 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 2.6E-6 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_01010 6852a028cc7de785d51f601609727715 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 256 2.1E-42 T 01-11-2018 MLA2C4_01010 6852a028cc7de785d51f601609727715 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_14805 efa2f093690bdac4f87f6a58d19bc993 225 Pfam PF03781 Sulfatase-modifying factor enzyme 1 11 223 1.2E-38 T 01-11-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MLA2C4_14805 efa2f093690bdac4f87f6a58d19bc993 225 Gene3D G3DSA:3.90.1580.10 3 224 3.8E-68 T 01-11-2018 MLA2C4_14805 efa2f093690bdac4f87f6a58d19bc993 225 SUPERFAMILY SSF56436 9 224 8.71E-55 T 01-11-2018 IPR016187 C-type lectin fold MLA2C4_12810 cc64646f96857879612580daeba11788 518 Gene3D G3DSA:3.40.50.300 4 285 4.2E-20 T 01-11-2018 MLA2C4_12810 cc64646f96857879612580daeba11788 518 SUPERFAMILY SSF52540 5 341 6.99E-12 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12810 cc64646f96857879612580daeba11788 518 Pfam PF13476 AAA domain 8 297 2.9E-21 T 01-11-2018 IPR038729 Rad50/SbcC-type AAA domain MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 Pfam PF11870 Domain of unknown function (DUF3390) 384 466 1.3E-16 T 01-11-2018 IPR024569 4Fe-4S binding protein, C-terminal MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 311 322 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 Gene3D G3DSA:3.40.50.10420 119 293 8.3E-15 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 SUPERFAMILY SSF100950 63 294 1.05E-41 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 Gene3D G3DSA:1.10.1060.10 302 390 8.3E-7 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 SUPERFAMILY SSF46548 269 398 9.24E-20 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 Pfam PF02589 LUD domain 69 293 2.4E-56 T 01-11-2018 IPR003741 LUD domain MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 452 1.9E-179 T 01-11-2018 IPR004452 4Fe-4S binding protein GO:0019516 MLA2C4_17060 1942fc55c9f607afc53825cf9aa0809e 470 Pfam PF13183 4Fe-4S dicluster domain 308 375 4.1E-11 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_01530 33a0dd1448f1a62f7d8a796db6dd388b 157 SUPERFAMILY SSF52540 26 120 3.68E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01530 33a0dd1448f1a62f7d8a796db6dd388b 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 11 135 7.0E-40 T 01-11-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MLA2C4_01530 33a0dd1448f1a62f7d8a796db6dd388b 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 131 8.4E-38 T 01-11-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MLA2C4_01530 33a0dd1448f1a62f7d8a796db6dd388b 157 Gene3D G3DSA:3.40.50.300 2 148 4.2E-41 T 01-11-2018 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 SMART SM00382 108 269 5.0E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 SMART SM00994 10 49 6.2E-24 T 01-11-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 SUPERFAMILY SSF57716 11 46 1.57E-11 T 01-11-2018 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Gene3D G3DSA:1.10.8.60 310 416 6.4E-37 T 01-11-2018 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.657 T 01-11-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 406 5.6E-213 T 01-11-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Pfam PF06689 ClpX C4-type zinc finger 12 48 4.8E-20 T 01-11-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Gene3D G3DSA:3.30.50.30 3 50 1.4E-21 T 01-11-2018 IPR038366 Zinc finger, ClpX C4-type superfamily MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 SUPERFAMILY SSF52540 59 395 7.55E-79 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 4.1E-51 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 1.1E-17 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 SMART SM01086 311 405 3.8E-33 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_23310 9d7693b93f8821a7bffb4c63f9272762 419 Gene3D G3DSA:3.40.50.300 53 309 1.2E-106 T 01-11-2018 MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 Pfam PF13537 Glutamine amidotransferase domain 48 169 1.4E-46 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 PIRSF PIRSF001589 1 606 1.3E-137 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 533 5.2E-157 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 SUPERFAMILY SSF52402 230 583 3.72E-68 T 01-11-2018 MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 SUPERFAMILY SSF56235 1 226 3.95E-66 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 Gene3D G3DSA:3.60.20.10 2 184 1.1E-64 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_08925 0f2453f953971a168982e1c5aad74217 607 Pfam PF00733 Asparagine synthase 243 599 1.4E-91 T 01-11-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 SUPERFAMILY SSF49503 179 351 2.09E-29 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 Gene3D G3DSA:2.60.40.420 28 364 3.5E-92 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 Gene3D G3DSA:2.60.40.420 377 518 5.0E-40 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 ProSitePatterns PS00080 Multicopper oxidases signature 2. 491 502 - T 01-11-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 SUPERFAMILY SSF49503 382 505 8.06E-36 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 SUPERFAMILY SSF49503 57 175 1.81E-37 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 Pfam PF07731 Multicopper oxidase 397 507 5.9E-29 T 01-11-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 Pfam PF00394 Multicopper oxidase 181 343 8.7E-16 T 01-11-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 ProSitePatterns PS00079 Multicopper oxidases signature 1. 486 506 - T 01-11-2018 IPR033138 Multicopper oxidases, conserved site MLA2C4_09660 458ee6cd271df56eb2f23bd2a1df460d 526 Pfam PF07732 Multicopper oxidase 65 175 4.2E-36 T 01-11-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 Gene3D G3DSA:3.40.50.300 526 691 7.8E-55 T 01-11-2018 MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 Pfam PF13361 UvrD-like helicase C-terminal domain 524 618 3.9E-7 T 01-11-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 Pfam PF00580 UvrD/REP helicase N-terminal domain 257 506 1.7E-10 T 01-11-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 Gene3D G3DSA:3.40.50.300 358 524 8.4E-10 T 01-11-2018 MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 SUPERFAMILY SSF52540 175 682 3.16E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 Gene3D G3DSA:3.40.50.300 171 321 1.5E-11 T 01-11-2018 MLA2C4_14880 65d66a4e7487898e3e93bd3c3ec2183c 691 Pfam PF13538 UvrD-like helicase C-terminal domain 630 677 4.4E-10 T 01-11-2018 IPR027785 UvrD-like helicase C-terminal domain MLA2C4_04385 2c82e4bd421cc7cff29c20eb8ff6d320 224 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_04385 2c82e4bd421cc7cff29c20eb8ff6d320 224 Pfam PF00005 ABC transporter 21 169 4.1E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_04385 2c82e4bd421cc7cff29c20eb8ff6d320 224 Gene3D G3DSA:3.40.50.300 1 223 2.4E-68 T 01-11-2018 MLA2C4_04385 2c82e4bd421cc7cff29c20eb8ff6d320 224 SMART SM00382 30 217 1.6E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_04385 2c82e4bd421cc7cff29c20eb8ff6d320 224 SUPERFAMILY SSF52540 1 221 1.87E-74 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15150 58fb469e3162db6cd8279168fe18a0c7 165 SUPERFAMILY SSF109854 14 156 1.83E-16 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_15150 58fb469e3162db6cd8279168fe18a0c7 165 Pfam PF12867 DinB superfamily 18 154 4.5E-11 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_15150 58fb469e3162db6cd8279168fe18a0c7 165 Gene3D G3DSA:1.20.120.450 11 163 9.2E-25 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 Pfam PF01497 Periplasmic binding protein 55 297 4.0E-31 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 301 314 3.1E-6 T 01-11-2018 MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 104 119 3.1E-6 T 01-11-2018 MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 72 90 3.1E-6 T 01-11-2018 MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 Gene3D G3DSA:3.40.50.1980 31 140 1.2E-29 T 01-11-2018 MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 SUPERFAMILY SSF53807 37 315 1.14E-55 T 01-11-2018 MLA2C4_23545 3d7ec0c2966dffa53e11577ecd663f1b 324 Gene3D G3DSA:3.40.50.1980 144 324 2.5E-36 T 01-11-2018 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 4.7E-40 T 01-11-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 SUPERFAMILY SSF51735 3 160 2.43E-33 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 3.0E-17 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 Gene3D G3DSA:1.10.3730.10 165 266 1.4E-39 T 01-11-2018 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 26.854 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 2.3E-85 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 SUPERFAMILY SSF48179 161 268 3.74E-39 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 PIRSF PIRSF000193 2 268 7.2E-83 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_16415 ff693faeedc9b70911fc49cc7db6f3a8 272 Gene3D G3DSA:3.40.50.720 1 164 5.2E-49 T 01-11-2018 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 56 1.8E-15 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 SUPERFAMILY SSF46689 1 72 2.05E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-7 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-7 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 Gene3D G3DSA:1.10.10.60 7 55 4.4E-19 T 01-11-2018 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 Pfam PF08360 QacR-like protein, C-terminal region 62 192 9.8E-61 T 01-11-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 Gene3D G3DSA:1.10.357.10 56 193 7.4E-42 T 01-11-2018 MLA2C4_02355 318fc911769f90655c9ab1f53b4e38fb 193 SUPERFAMILY SSF48498 78 191 1.3E-38 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 SUPERFAMILY SSF56194 197 300 4.97E-38 T 01-11-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 301 90.224 T 01-11-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 Pfam PF01565 FAD binding domain 35 163 1.2E-22 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 Gene3D G3DSA:3.30.43.10 1 88 5.7E-25 T 01-11-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 Gene3D G3DSA:3.90.78.10 217 301 1.5E-34 T 01-11-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 SUPERFAMILY SSF56176 14 193 9.0E-41 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 2.4E-97 T 01-11-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 203 299 2.2E-29 T 01-11-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_20430 4411fc14974f22edcc164902e2945dd7 301 Gene3D G3DSA:3.30.465.10 89 216 2.1E-44 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_00590 849d63ab795def0b3a69ab0f13ed22ed 48 Gene3D G3DSA:2.20.28.120 1 48 4.5E-18 T 01-11-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00590 849d63ab795def0b3a69ab0f13ed22ed 48 Pfam PF00471 Ribosomal protein L33 3 48 7.6E-18 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00590 849d63ab795def0b3a69ab0f13ed22ed 48 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 48 6.2E-16 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00590 849d63ab795def0b3a69ab0f13ed22ed 48 SUPERFAMILY SSF57829 1 48 3.97E-15 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MLA2C4_00590 849d63ab795def0b3a69ab0f13ed22ed 48 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 48 17.553 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 Gene3D G3DSA:3.90.1150.10 6 395 9.9E-185 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 Pfam PF00266 Aminotransferase class-V 23 391 1.6E-164 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 PIRSF PIRSF005572 20 404 6.0E-56 T 01-11-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 01-11-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 SUPERFAMILY SSF53383 2 398 1.43E-133 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 4.4E-192 T 01-11-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MLA2C4_25915 725589aa4c2127a836fd8aace93e0b33 406 Gene3D G3DSA:3.40.640.10 34 294 9.9E-185 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_01940 65d4d0fb1932dafcd931354579488526 483 Gene3D G3DSA:3.40.309.10 261 451 2.6E-182 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_01940 65d4d0fb1932dafcd931354579488526 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 01-11-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MLA2C4_01940 65d4d0fb1932dafcd931354579488526 483 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 477 5.1E-203 T 01-11-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 MLA2C4_01940 65d4d0fb1932dafcd931354579488526 483 Gene3D G3DSA:3.40.605.10 21 474 2.6E-182 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_01940 65d4d0fb1932dafcd931354579488526 483 Pfam PF00171 Aldehyde dehydrogenase family 25 478 1.2E-172 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_01940 65d4d0fb1932dafcd931354579488526 483 SUPERFAMILY SSF53720 12 482 3.4E-173 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_18405 2da73c6843dc90e330158ae629b815ac 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 94 122 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_18405 2da73c6843dc90e330158ae629b815ac 185 SUPERFAMILY SSF51161 28 175 1.8E-44 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_18405 2da73c6843dc90e330158ae629b815ac 185 Gene3D G3DSA:2.160.10.10 2 183 3.8E-60 T 01-11-2018 MLA2C4_18405 2da73c6843dc90e330158ae629b815ac 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 86 120 1.2E-7 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_11650 fd67779e169bf9e881e1fe85bbca3ebb 168 Pfam PF08864 UPF0302 domain 8 112 2.1E-31 T 01-11-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal MLA2C4_11650 fd67779e169bf9e881e1fe85bbca3ebb 168 Gene3D G3DSA:1.20.1440.290 1 120 3.4E-37 T 01-11-2018 IPR038091 UPF0302, N-terminal domain superfamily MLA2C4_11650 fd67779e169bf9e881e1fe85bbca3ebb 168 PIRSF PIRSF007165 1 168 1.4E-38 T 01-11-2018 IPR011188 Uncharacterised protein family UPF0302 MLA2C4_24470 5a5ff035210b73ca8a5bc1968ae86d6c 73 SMART SM00420 11 56 8.0E-4 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_24470 5a5ff035210b73ca8a5bc1968ae86d6c 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 50 8.6E-11 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_24470 5a5ff035210b73ca8a5bc1968ae86d6c 73 SUPERFAMILY SSF46785 10 58 5.17E-9 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_24470 5a5ff035210b73ca8a5bc1968ae86d6c 73 Gene3D G3DSA:1.10.10.10 10 71 1.5E-6 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_06260 ba829c3c61412f5eb6a9d7819dd76b0c 224 Pfam PF03741 Integral membrane protein TerC family 11 181 1.1E-43 T 01-11-2018 IPR005496 Integral membrane protein TerC GO:0016021 MLA2C4_06260 ba829c3c61412f5eb6a9d7819dd76b0c 224 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 182 5.7E-70 T 01-11-2018 IPR022301 Integral membrane protein YjbE MLA2C4_15580 1acfeaf94048f2c622dd4c5a20069b15 145 Pfam PF10710 Protein of unknown function (DUF2512) 4 135 5.4E-42 T 01-11-2018 IPR019649 Protein of unknown function DUF2512 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 SUPERFAMILY SSF47384 113 196 1.79E-16 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 247 351 3.7E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 Gene3D G3DSA:1.10.287.130 125 201 5.1E-18 T 01-11-2018 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 SUPERFAMILY SSF55874 186 351 1.96E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 SMART SM00388 130 197 1.4E-11 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 Pfam PF00512 His Kinase A (phospho-acceptor) domain 130 191 8.8E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 SUPERFAMILY SSF158472 72 121 5.1E-10 T 01-11-2018 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 SMART SM00387 242 353 1.9E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 307 1.0E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 350 1.0E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 PRINTS PR00344 Bacterial sensor protein C-terminal signature 314 332 1.0E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 Gene3D G3DSA:3.30.565.10 202 354 3.8E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 Pfam PF00672 HAMP domain 71 118 8.3E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 Gene3D G3DSA:1.20.1480.50 29 124 2.2E-15 T 01-11-2018 MLA2C4_09560 299e916112b9016dc221a083bba61df3 355 SMART SM00304 70 122 9.3E-11 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26500 c8a2213b13fc930871c902a56ea5574f 337 Gene3D G3DSA:3.40.50.1980 54 323 1.0E-69 T 01-11-2018 MLA2C4_26500 c8a2213b13fc930871c902a56ea5574f 337 SUPERFAMILY SSF53807 44 321 1.65E-51 T 01-11-2018 MLA2C4_26500 c8a2213b13fc930871c902a56ea5574f 337 Pfam PF01497 Periplasmic binding protein 63 314 5.0E-35 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_26500 c8a2213b13fc930871c902a56ea5574f 337 Gene3D G3DSA:3.40.50.12260 202 312 1.0E-69 T 01-11-2018 MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 Gene3D G3DSA:1.20.5.1170 118 144 2.0E-20 T 01-11-2018 MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 Pfam PF01230 HIT domain 16 110 3.4E-27 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 Gene3D G3DSA:3.30.428.10 1 117 2.0E-40 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 ProSitePatterns PS00892 HIT domain signature. 90 108 - T 01-11-2018 IPR019808 Histidine triad, conserved site MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 SUPERFAMILY SSF54197 6 140 5.26E-47 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 PRINTS PR00332 Histidine triad family signature 97 107 1.9E-17 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 PRINTS PR00332 Histidine triad family signature 30 48 1.9E-17 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_05580 be9a188fe617930cb2df18e76c196f0a 144 PRINTS PR00332 Histidine triad family signature 9 25 1.9E-17 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_10975 5fa67e14b30b8025ecc727cb8545bf0a 144 Gene3D G3DSA:3.40.30.10 25 144 1.0E-51 T 01-11-2018 MLA2C4_10975 5fa67e14b30b8025ecc727cb8545bf0a 144 Pfam PF06491 Disulphide isomerase 8 144 6.9E-61 T 01-11-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family MLA2C4_10975 5fa67e14b30b8025ecc727cb8545bf0a 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 5.5E-64 T 01-11-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 287 1.4E-68 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 SUPERFAMILY SSF160240 209 287 3.4E-21 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 Pfam PF01545 Cation efflux family 14 205 3.4E-50 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 Gene3D G3DSA:3.30.70.1350 206 287 7.1E-17 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 285 9.7E-19 T 01-11-2018 IPR027470 Cation efflux protein, cytoplasmic domain MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 SUPERFAMILY SSF161111 7 207 7.32E-54 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily MLA2C4_11545 cd40a02895b28e942e985ea89d6efbd8 293 Gene3D G3DSA:1.20.1510.10 9 205 1.7E-57 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 Gene3D G3DSA:3.30.70.580 1 105 1.5E-34 T 01-11-2018 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 SUPERFAMILY SSF55120 2 247 2.3E-84 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 240 8.6E-68 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 Pfam PF01416 tRNA pseudouridine synthase 8 104 1.0E-8 T 01-11-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 Pfam PF01416 tRNA pseudouridine synthase 144 246 2.2E-34 T 01-11-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.878 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 Gene3D G3DSA:3.30.70.660 107 244 3.0E-49 T 01-11-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 MLA2C4_00835 d5a074e888a4a16db77418dc1dfa4eed 247 PIRSF PIRSF001430 1 247 5.1E-84 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_09120 7f9ef53cf30ef212cf1e0fba05a7db02 436 SUPERFAMILY SSF50494 17 187 1.91E-11 T 01-11-2018 IPR009003 Peptidase S1, PA clan MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 SUPERFAMILY SSF55785 7 112 8.55E-13 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Gene3D G3DSA:3.40.50.300 137 321 1.3E-60 T 01-11-2018 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 SUPERFAMILY SSF46689 364 455 2.58E-18 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Gene3D G3DSA:1.10.8.60 322 388 9.0E-26 T 01-11-2018 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 SUPERFAMILY SSF52540 152 394 1.46E-64 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 SMART SM00382 172 315 1.3E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Gene3D G3DSA:3.30.450.20 4 117 3.2E-13 T 01-11-2018 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Pfam PF02954 Bacterial regulatory protein, Fis family 414 454 5.0E-14 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Gene3D G3DSA:1.10.10.60 389 457 7.9E-16 T 01-11-2018 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 120 1.1E-6 T 01-11-2018 IPR000014 PAS domain MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Pfam PF00158 Sigma-54 interaction domain 152 317 1.3E-62 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 364 373 - T 01-11-2018 IPR025944 Sigma-54 interaction domain, conserved site MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 Pfam PF08448 PAS fold 16 117 3.5E-6 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 176 189 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 2.9E-10 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_11490 29beb15af63023f3cc61199136a174a1 459 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 457 2.9E-10 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Gene3D G3DSA:3.30.930.10 226 533 1.1E-134 T 01-11-2018 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Gene3D G3DSA:3.40.50.800 534 639 1.1E-32 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 70 637 35.304 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 222 2.3E-15 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 SUPERFAMILY SSF81271 6 65 6.54E-16 T 01-11-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 SMART SM00863 173 222 2.1E-23 T 01-11-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 530 6.0E-42 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Gene3D G3DSA:3.30.54.20 134 190 2.1E-63 T 01-11-2018 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Gene3D G3DSA:3.10.20.30 3 66 5.4E-25 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 SUPERFAMILY SSF52954 529 637 1.37E-32 T 01-11-2018 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 332 360 4.7E-53 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 365 388 4.7E-53 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 4.7E-53 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 4.7E-53 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 4.7E-53 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 SUPERFAMILY SSF55681 246 528 2.21E-97 T 01-11-2018 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 SUPERFAMILY SSF55186 67 244 1.1E-64 T 01-11-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Pfam PF03129 Anticodon binding domain 543 633 8.7E-21 T 01-11-2018 IPR004154 Anticodon-binding MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Gene3D G3DSA:3.30.980.10 73 225 2.1E-63 T 01-11-2018 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 76 634 1.7E-235 T 01-11-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MLA2C4_12275 75439ddc4dba5ddcf419698df3e460e9 639 Pfam PF02824 TGS domain 7 65 2.3E-13 T 01-11-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MLA2C4_20395 2fade3680a1485c53fd636bc146779b1 92 Gene3D G3DSA:2.30.30.240 1 77 1.3E-12 T 01-11-2018 MLA2C4_20395 2fade3680a1485c53fd636bc146779b1 92 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 75 9.4E-27 T 01-11-2018 IPR014238 Sporulation protein YlmC/YmxH MLA2C4_20395 2fade3680a1485c53fd636bc146779b1 92 Pfam PF05239 PRC-barrel domain 1 76 4.5E-14 T 01-11-2018 IPR027275 PRC-barrel domain MLA2C4_20395 2fade3680a1485c53fd636bc146779b1 92 SUPERFAMILY SSF50346 1 74 1.07E-14 T 01-11-2018 IPR011033 PRC-barrel-like superfamily MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 Gene3D G3DSA:1.10.1660.10 1 113 1.3E-24 T 01-11-2018 MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 SUPERFAMILY SSF55136 119 269 2.79E-19 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 Pfam PF14526 Integron-associated effector binding protein 121 268 1.2E-15 T 01-11-2018 IPR029441 Integron-associated effector binding protein MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 Gene3D G3DSA:3.20.80.10 114 269 1.4E-23 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 SMART SM00871 118 269 2.1E-25 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 SUPERFAMILY SSF46955 2 105 2.16E-22 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.5E-13 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_13620 f99b13305e32e2b5b33d5821f61f4d41 269 SMART SM00422 2 72 1.1E-15 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 1.6E-5 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 1.6E-5 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 SUPERFAMILY SSF46785 6 62 3.11E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 SMART SM00420 8 60 4.6E-11 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 Gene3D G3DSA:1.10.10.10 1 56 2.6E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 3.9E-12 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 Pfam PF00455 DeoR C terminal sensor domain 77 240 1.1E-42 T 01-11-2018 IPR014036 DeoR C-terminal sensor domain MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 SUPERFAMILY SSF100950 75 241 8.37E-32 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_07050 7e9694efc1b3ae46dc9603735c920504 260 SMART SM01134 75 241 2.6E-57 T 01-11-2018 MLA2C4_12570 30cc91774824b324d47ad0ecf456be8a 125 SUPERFAMILY SSF159121 27 124 1.57E-28 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_12570 30cc91774824b324d47ad0ecf456be8a 125 Pfam PF06486 Protein of unknown function (DUF1093) 28 112 6.0E-18 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_12570 30cc91774824b324d47ad0ecf456be8a 125 Gene3D G3DSA:2.40.50.480 23 125 2.3E-36 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 SUPERFAMILY SSF52402 16 197 6.47E-51 T 01-11-2018 MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 42.598 T 01-11-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 232 5.1E-88 T 01-11-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 43 231 1.6E-71 T 01-11-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 37 209 1.3E-49 T 01-11-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 Gene3D G3DSA:3.40.50.620 5 234 5.1E-74 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_07510 78ad7c5460cca326619243214c462c9e 234 PIRSF PIRSF000857 3 234 2.6E-88 T 01-11-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 SUPERFAMILY SSF53850 98 289 5.79E-27 T 01-11-2018 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 Gene3D G3DSA:1.10.10.10 4 90 4.6E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 1.2E-15 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 Gene3D G3DSA:3.40.190.290 91 290 3.2E-63 T 01-11-2018 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 SUPERFAMILY SSF46785 8 120 8.84E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.8E-6 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.8E-6 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.8E-6 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_20815 2c14eb87862bd7f83350cedfcb92c7d0 294 Pfam PF03466 LysR substrate binding domain 97 289 1.3E-31 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_15070 100311f474a537f0ca89a80827c3e5c6 540 PIRSF PIRSF002741 1 540 9.0E-97 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_15070 100311f474a537f0ca89a80827c3e5c6 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 459 2.1E-75 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_15070 100311f474a537f0ca89a80827c3e5c6 540 Gene3D G3DSA:3.90.76.10 68 189 8.7E-174 T 01-11-2018 MLA2C4_15070 100311f474a537f0ca89a80827c3e5c6 540 Gene3D G3DSA:3.40.190.10 49 528 8.7E-174 T 01-11-2018 MLA2C4_15070 100311f474a537f0ca89a80827c3e5c6 540 Gene3D G3DSA:3.10.105.10 289 511 8.7E-174 T 01-11-2018 MLA2C4_15070 100311f474a537f0ca89a80827c3e5c6 540 SUPERFAMILY SSF53850 35 530 1.05E-120 T 01-11-2018 MLA2C4_23400 8833c4d9f21394c6444c932dba8c6217 220 SUPERFAMILY SSF52317 1 215 1.46E-63 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_23400 8833c4d9f21394c6444c932dba8c6217 220 Gene3D G3DSA:3.40.50.880 1 219 3.2E-70 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_23400 8833c4d9f21394c6444c932dba8c6217 220 Pfam PF01965 DJ-1/PfpI family 26 213 1.8E-15 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 SMART SM00387 294 400 9.8E-26 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 Pfam PF00512 His Kinase A (phospho-acceptor) domain 188 248 1.8E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 Gene3D G3DSA:3.30.565.10 247 399 7.4E-35 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 SUPERFAMILY SSF55874 244 398 1.7E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 398 1.5E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 SMART SM00388 186 252 1.8E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 SUPERFAMILY SSF47384 182 250 5.3E-14 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 Pfam PF07694 5TMR of 5TMR-LYT 14 164 6.6E-12 T 01-11-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 Gene3D G3DSA:1.10.287.130 176 246 1.2E-17 T 01-11-2018 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 1.0E-14 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 345 1.0E-14 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 359 1.0E-14 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 1.0E-14 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07105 e17f869f64908823f9038c46a584fb8c 402 Gene3D G3DSA:1.10.1760.20 19 175 6.1E-6 T 01-11-2018 MLA2C4_13075 132d1aedf4d36fca2a13b9259e35258b 499 Gene3D G3DSA:2.40.30.200 2 135 3.2E-36 T 01-11-2018 IPR038675 Streptococcus phage 7201 Orf34, N-terminal domain superfamily MLA2C4_13075 132d1aedf4d36fca2a13b9259e35258b 499 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 4 133 1.9E-22 T 01-11-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal MLA2C4_13075 132d1aedf4d36fca2a13b9259e35258b 499 Pfam PF05709 Phage tail protein 24 499 4.1E-50 T 01-11-2018 IPR008841 Siphovirus-type tail component MLA2C4_05010 ef7fd32e8cece622291cbf53d6f81aeb 261 SUPERFAMILY SSF46785 2 97 3.11E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05010 ef7fd32e8cece622291cbf53d6f81aeb 261 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 228 5.1E-7 T 01-11-2018 IPR021586 Transcription regulator TrmB, C-terminal MLA2C4_05010 ef7fd32e8cece622291cbf53d6f81aeb 261 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 76 1.9E-23 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal MLA2C4_05010 ef7fd32e8cece622291cbf53d6f81aeb 261 Gene3D G3DSA:1.10.10.10 2 102 2.5E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15725 c9efd0190e9608f10ea3eced775d2706 347 SMART SM00418 269 343 9.3E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_15725 c9efd0190e9608f10ea3eced775d2706 347 Gene3D G3DSA:1.10.10.10 265 344 1.0E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15725 c9efd0190e9608f10ea3eced775d2706 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 271 286 3.7E-6 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_15725 c9efd0190e9608f10ea3eced775d2706 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 303 318 3.7E-6 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_15725 c9efd0190e9608f10ea3eced775d2706 347 Pfam PF01022 Bacterial regulatory protein, arsR family 276 320 4.7E-13 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_15725 c9efd0190e9608f10ea3eced775d2706 347 SUPERFAMILY SSF46785 268 345 6.07E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_25345 630eae691dd6194b3cf79bfc10787f86 342 Gene3D G3DSA:2.60.40.1630 71 216 4.2E-10 T 01-11-2018 MLA2C4_25345 630eae691dd6194b3cf79bfc10787f86 342 Pfam PF13786 Domain of unknown function (DUF4179) 37 128 1.1E-13 T 01-11-2018 IPR025436 Domain of unknown function DUF4179 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Gene3D G3DSA:1.10.287.110 1 110 6.0E-38 T 01-11-2018 IPR036869 Chaperone J-domain superfamily MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Pfam PF01556 DnaJ C terminal domain 119 336 1.7E-43 T 01-11-2018 IPR002939 Chaperone DnaJ, C-terminal MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Gene3D G3DSA:2.10.230.10 146 210 9.1E-36 T 01-11-2018 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Gene3D G3DSA:2.60.260.20 116 252 9.1E-36 T 01-11-2018 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Gene3D G3DSA:2.60.260.20 256 336 1.8E-30 T 01-11-2018 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 PRINTS PR00625 DnaJ domain signature 41 61 5.3E-31 T 01-11-2018 IPR001623 DnaJ domain MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 PRINTS PR00625 DnaJ domain signature 61 80 5.3E-31 T 01-11-2018 IPR001623 DnaJ domain MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 PRINTS PR00625 DnaJ domain signature 25 40 5.3E-31 T 01-11-2018 IPR001623 DnaJ domain MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 PRINTS PR00625 DnaJ domain signature 7 25 5.3E-31 T 01-11-2018 IPR001623 DnaJ domain MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 5.1E-142 T 01-11-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Pfam PF00226 DnaJ domain 5 66 1.7E-27 T 01-11-2018 IPR001623 DnaJ domain MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 SUPERFAMILY SSF49493 261 347 5.62E-25 T 01-11-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 SMART SM00271 4 61 1.5E-30 T 01-11-2018 IPR001623 DnaJ domain MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 SUPERFAMILY SSF49493 113 266 1.02E-19 T 01-11-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Pfam PF00684 DnaJ central domain 146 210 1.2E-13 T 01-11-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 01-11-2018 IPR018253 DnaJ domain, conserved site MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 SUPERFAMILY SSF57938 133 214 1.83E-18 T 01-11-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 367 41.508 T 01-11-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MLA2C4_22525 10b7143b5e8e5c729ade4433e4ffec3f 371 SUPERFAMILY SSF46565 1 104 1.83E-37 T 01-11-2018 IPR036869 Chaperone J-domain superfamily MLA2C4_25080 524d878c7c13d9414e59a40d427a9063 300 SUPERFAMILY SSF111331 6 297 5.49E-76 T 01-11-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MLA2C4_25080 524d878c7c13d9414e59a40d427a9063 300 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 130 4.8E-35 T 01-11-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MLA2C4_25080 524d878c7c13d9414e59a40d427a9063 300 Gene3D G3DSA:2.60.200.40 129 281 4.7E-102 T 01-11-2018 MLA2C4_25080 524d878c7c13d9414e59a40d427a9063 300 Gene3D G3DSA:3.40.50.10330 10 128 4.7E-102 T 01-11-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MLA2C4_25080 524d878c7c13d9414e59a40d427a9063 300 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 7 293 1.6E-80 T 01-11-2018 IPR005218 Diacylglycerol/lipid kinase MLA2C4_25080 524d878c7c13d9414e59a40d427a9063 300 SMART SM00046 8 134 4.5E-15 T 01-11-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 327 6.0E-120 T 01-11-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 SUPERFAMILY SSF53774 1 330 6.41E-102 T 01-11-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 SMART SM00870 3 315 5.9E-119 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 PIRSF PIRSF001220 1 325 8.5E-94 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 Pfam PF00710 Asparaginase, N-terminal 3 187 7.2E-66 T 01-11-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 Gene3D G3DSA:3.40.50.1170 1 199 2.4E-70 T 01-11-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 3.2E-16 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 PRINTS PR00139 Asparaginase/glutaminase family signature 252 270 3.2E-16 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 3.2E-16 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 01-11-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 01-11-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 Gene3D G3DSA:3.40.50.40 200 333 1.1E-35 T 01-11-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MLA2C4_16350 b40c2fb0180973ff41266df5b6923dd6 334 PIRSF PIRSF500176 1 324 1.3E-103 T 01-11-2018 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 122 201 9.8E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 201 3.5E-26 T 01-11-2018 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 SUPERFAMILY SSF56784 1 232 1.68E-42 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 167 1.1E-6 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 1.1E-6 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 1.1E-6 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 Gene3D G3DSA:1.10.150.240 19 106 2.4E-29 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_01925 b3927e048079cc9e7a396aa3e2c6bf97 248 Gene3D G3DSA:3.40.50.1000 7 227 2.4E-29 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 Gene3D G3DSA:3.60.21.10 35 341 2.7E-81 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 ProSitePatterns PS00786 5'-nucleotidase signature 2. 114 125 - T 01-11-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 SUPERFAMILY SSF55816 339 528 5.62E-56 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 Gene3D G3DSA:3.90.780.10 345 528 5.9E-59 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 SUPERFAMILY SSF56300 33 341 3.8E-77 T 01-11-2018 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 Pfam PF00149 Calcineurin-like phosphoesterase 41 269 5.4E-11 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 Pfam PF02872 5'-nucleotidase, C-terminal domain 342 490 6.0E-47 T 01-11-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 PRINTS PR01607 Apyrase family signature 36 54 5.5E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 PRINTS PR01607 Apyrase family signature 222 239 5.5E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 PRINTS PR01607 Apyrase family signature 394 417 5.5E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 PRINTS PR01607 Apyrase family signature 251 274 5.5E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 PRINTS PR01607 Apyrase family signature 465 484 5.5E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_16485 fcc370ffc3c50f01005448ef561e2853 529 PRINTS PR01607 Apyrase family signature 277 297 5.5E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_07790 2bd8fab0b3cacf7bd56153733373be5c 193 Gene3D G3DSA:1.20.1200.10 12 193 5.5E-73 T 01-11-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MLA2C4_07790 2bd8fab0b3cacf7bd56153733373be5c 193 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 177 3.9E-64 T 01-11-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MLA2C4_07790 2bd8fab0b3cacf7bd56153733373be5c 193 SUPERFAMILY SSF89028 1 178 5.69E-64 T 01-11-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MLA2C4_07790 2bd8fab0b3cacf7bd56153733373be5c 193 Pfam PF01923 Cobalamin adenosyltransferase 4 166 1.7E-57 T 01-11-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MLA2C4_07790 2bd8fab0b3cacf7bd56153733373be5c 193 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 179 1.0E-89 T 01-11-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MLA2C4_06475 bf9ead03b6cde33e32a5beb6a135728e 132 Gene3D G3DSA:2.60.40.1080 38 125 4.0E-17 T 01-11-2018 MLA2C4_06475 bf9ead03b6cde33e32a5beb6a135728e 132 SUPERFAMILY SSF49373 39 122 1.18E-8 T 01-11-2018 IPR008964 Invasin/intimin cell-adhesion fragments MLA2C4_06475 bf9ead03b6cde33e32a5beb6a135728e 132 Pfam PF02368 Bacterial Ig-like domain (group 2) 44 115 2.7E-6 T 01-11-2018 IPR003343 Bacterial Ig-like, group 2 MLA2C4_06475 bf9ead03b6cde33e32a5beb6a135728e 132 SMART SM00635 41 121 0.0031 T 01-11-2018 IPR003343 Bacterial Ig-like, group 2 MLA2C4_23025 b61ab1eaf99d9880c9414758b4ff9cfc 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 84 1.5E-29 T 01-11-2018 IPR003849 Preprotein translocase YajC MLA2C4_23025 b61ab1eaf99d9880c9414758b4ff9cfc 86 Pfam PF02699 Preprotein translocase subunit 7 81 8.4E-30 T 01-11-2018 IPR003849 Preprotein translocase YajC MLA2C4_23025 b61ab1eaf99d9880c9414758b4ff9cfc 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 5 25 6.3E-15 T 01-11-2018 IPR003849 Preprotein translocase YajC MLA2C4_23025 b61ab1eaf99d9880c9414758b4ff9cfc 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 6.3E-15 T 01-11-2018 IPR003849 Preprotein translocase YajC MLA2C4_23025 b61ab1eaf99d9880c9414758b4ff9cfc 86 SMART SM01323 3 84 3.2E-41 T 01-11-2018 IPR003849 Preprotein translocase YajC MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 Pfam PF00072 Response regulator receiver domain 4 114 1.1E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.2E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 SMART SM00448 2 113 5.0E-39 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 Gene3D G3DSA:1.10.10.10 127 228 1.9E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 SMART SM00862 148 224 6.3E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 Gene3D G3DSA:3.40.50.2300 1 126 3.0E-35 T 01-11-2018 MLA2C4_10045 f4ddad51cc1d8f051aa7196e81246442 229 SUPERFAMILY SSF52172 1 169 1.46E-40 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_13375 ccc06757e33c7bdb514dda5f28880388 349 Gene3D G3DSA:3.40.50.720 1 116 1.1E-32 T 01-11-2018 MLA2C4_13375 ccc06757e33c7bdb514dda5f28880388 349 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 117 1.3E-25 T 01-11-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MLA2C4_13375 ccc06757e33c7bdb514dda5f28880388 349 SUPERFAMILY SSF51735 2 147 1.75E-44 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_13375 ccc06757e33c7bdb514dda5f28880388 349 Gene3D G3DSA:3.30.360.10 117 347 8.1E-37 T 01-11-2018 MLA2C4_13375 ccc06757e33c7bdb514dda5f28880388 349 SUPERFAMILY SSF55347 125 296 7.52E-21 T 01-11-2018 MLA2C4_13375 ccc06757e33c7bdb514dda5f28880388 349 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 129 239 1.2E-17 T 01-11-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 Gene3D G3DSA:3.90.1640.10 317 531 9.1E-50 T 01-11-2018 MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 Pfam PF02272 DHHA1 domain 518 644 1.4E-11 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 SMART SM00267 132 299 3.0E-5 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 SUPERFAMILY SSF64182 339 641 5.49E-70 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 PIRSF PIRSF026583 1 657 2.0E-277 T 01-11-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 Pfam PF01368 DHH family 339 496 1.4E-22 T 01-11-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 Gene3D G3DSA:3.10.310.30 532 652 2.9E-7 T 01-11-2018 MLA2C4_28390 7d9fd35ae2a93b8f25b7333c6058fbdc 657 Gene3D G3DSA:3.30.450.20 53 161 8.1E-32 T 01-11-2018 MLA2C4_13235 2305db09f78ce17dfec1de9a08583847 406 SUPERFAMILY SSF103473 4 399 6.41E-37 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_13235 2305db09f78ce17dfec1de9a08583847 406 Gene3D G3DSA:1.20.1250.20 2 399 1.3E-38 T 01-11-2018 MLA2C4_13235 2305db09f78ce17dfec1de9a08583847 406 Pfam PF07690 Major Facilitator Superfamily 9 363 4.5E-24 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_01855 dd94e579f9a21b5a5e693052e0e202ff 187 SUPERFAMILY SSF52499 2 180 2.62E-53 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_01855 dd94e579f9a21b5a5e693052e0e202ff 187 Gene3D G3DSA:3.40.50.850 1 186 3.2E-51 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_01855 dd94e579f9a21b5a5e693052e0e202ff 187 Pfam PF00857 Isochorismatase family 3 175 1.5E-33 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_04500 12579687969dd0c34d50527afcd3f1fd 287 Pfam PF01380 SIS domain 130 259 2.1E-23 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_04500 12579687969dd0c34d50527afcd3f1fd 287 Gene3D G3DSA:3.40.50.10490 98 280 1.3E-44 T 01-11-2018 MLA2C4_04500 12579687969dd0c34d50527afcd3f1fd 287 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 77 1.3E-15 T 01-11-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MLA2C4_04500 12579687969dd0c34d50527afcd3f1fd 287 SUPERFAMILY SSF46689 5 77 4.66E-18 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_04500 12579687969dd0c34d50527afcd3f1fd 287 Gene3D G3DSA:1.10.10.10 2 79 3.0E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04500 12579687969dd0c34d50527afcd3f1fd 287 SUPERFAMILY SSF53697 96 282 6.15E-43 T 01-11-2018 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 SUPERFAMILY SSF52540 53 294 9.91E-40 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 194 211 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 91 106 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 143 162 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 271 283 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 211 230 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 129 143 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 173 185 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 PRINTS PR00819 CbxX/CfqX superfamily signature 51 65 1.6E-58 T 01-11-2018 IPR000641 CbxX/CfqX GO:0005524 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 48 309 7.7E-134 T 01-11-2018 IPR014232 Sporulation stage V, protein K MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 SMART SM00382 88 226 3.8E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 Gene3D G3DSA:3.40.50.300 26 223 2.1E-58 T 01-11-2018 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 Gene3D G3DSA:1.10.8.60 224 314 4.1E-18 T 01-11-2018 MLA2C4_19375 e97eaf0b918b2d2652e762dfd8ca3b7f 318 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 92 222 1.0E-19 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_14220 37ebeb07f4085c5d3368fcee859c6261 176 Pfam PF14091 Domain of unknown function (DUF4269) 21 168 1.0E-59 T 01-11-2018 IPR025365 Protein of unknown function DUF4269 MLA2C4_15345 026160df7e3c6fcf162eb2df50437188 132 Gene3D G3DSA:3.10.129.10 1 131 4.9E-32 T 01-11-2018 MLA2C4_15345 026160df7e3c6fcf162eb2df50437188 132 Pfam PF07977 FabA-like domain 7 123 1.9E-14 T 01-11-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_15345 026160df7e3c6fcf162eb2df50437188 132 SUPERFAMILY SSF54637 3 125 8.34E-29 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 Pfam PF01381 Helix-turn-helix 20 72 5.4E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 SUPERFAMILY SSF47413 12 76 7.88E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 SMART SM00530 19 74 2.9E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 Pfam PF07883 Cupin domain 126 182 4.8E-11 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 Gene3D G3DSA:2.60.120.10 98 190 1.5E-22 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 SUPERFAMILY SSF51182 68 186 3.53E-17 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_23425 bd5c11c8182edc78bf319736cec168ed 190 Gene3D G3DSA:1.10.260.40 6 81 1.4E-18 T 01-11-2018 MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 Gene3D G3DSA:1.10.1740.10 1 115 1.9E-18 T 01-11-2018 MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 177 3.1E-28 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 Gene3D G3DSA:1.10.10.10 120 181 1.4E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 SUPERFAMILY SSF88946 8 98 2.51E-21 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 Pfam PF04542 Sigma-70 region 2 25 91 1.2E-11 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 SUPERFAMILY SSF88659 113 176 1.1E-16 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_10755 492e7b3ddadb0651fff435f6c223c583 192 Pfam PF08281 Sigma-70, region 4 122 174 1.0E-16 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_15800 784e86f45ecc8e81fb7c6540222ca787 71 SUPERFAMILY SSF47413 1 68 1.35E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_15800 784e86f45ecc8e81fb7c6540222ca787 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 1.8E-24 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_15800 784e86f45ecc8e81fb7c6540222ca787 71 Gene3D G3DSA:1.10.260.40 1 71 2.0E-10 T 01-11-2018 MLA2C4_15800 784e86f45ecc8e81fb7c6540222ca787 71 SMART SM00530 6 62 1.7E-6 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_16740 c2623cb312fccb0c176ec2703a256a1c 331 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 85 157 2.0E-20 T 01-11-2018 IPR024542 Domain of unknown function DUF3880 MLA2C4_16740 c2623cb312fccb0c176ec2703a256a1c 331 Pfam PF13524 Glycosyl transferases group 1 216 321 5.0E-23 T 01-11-2018 MLA2C4_00825 388567632df03889ace59fe891202e67 293 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 1.7E-122 T 01-11-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 MLA2C4_00825 388567632df03889ace59fe891202e67 293 SMART SM00382 32 223 3.7E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00825 388567632df03889ace59fe891202e67 293 Gene3D G3DSA:3.40.50.300 2 287 1.3E-75 T 01-11-2018 MLA2C4_00825 388567632df03889ace59fe891202e67 293 SUPERFAMILY SSF52540 19 237 1.01E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00825 388567632df03889ace59fe891202e67 293 Pfam PF00005 ABC transporter 24 174 1.9E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_00825 388567632df03889ace59fe891202e67 293 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_13865 a8ca2f4d7be8665a7b3e154dcdee1bf7 113 Pfam PF13053 Protein of unknown function (DUF3914) 1 89 1.9E-51 T 01-11-2018 IPR025025 Protein of unknown function DUF3914 MLA2C4_09505 81339433ce575e76af3c2aaeaf5b8e83 201 SUPERFAMILY SSF141571 23 199 2.45E-46 T 01-11-2018 MLA2C4_09505 81339433ce575e76af3c2aaeaf5b8e83 201 Pfam PF00805 Pentapeptide repeats (8 copies) 113 151 6.7E-10 T 01-11-2018 IPR001646 Pentapeptide repeat MLA2C4_09505 81339433ce575e76af3c2aaeaf5b8e83 201 Pfam PF00805 Pentapeptide repeats (8 copies) 154 184 0.0035 T 01-11-2018 IPR001646 Pentapeptide repeat MLA2C4_09505 81339433ce575e76af3c2aaeaf5b8e83 201 Gene3D G3DSA:2.160.20.100 3 201 4.3E-53 T 01-11-2018 MLA2C4_09505 81339433ce575e76af3c2aaeaf5b8e83 201 Pfam PF13599 Pentapeptide repeats (9 copies) 13 79 6.2E-7 T 01-11-2018 IPR001646 Pentapeptide repeat MLA2C4_28240 c380942dff2ae0cb76392c9edf37ceb4 306 Gene3D G3DSA:1.25.40.10 102 277 1.3E-7 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_28240 c380942dff2ae0cb76392c9edf37ceb4 306 SUPERFAMILY SSF48452 207 273 1.33E-5 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_06055 eb88fce93874f86646e0bf21e63702e8 122 Hamap MF_01536 UPF0344 protein . 1 121 16.871 T 01-11-2018 IPR010899 Protein of unknown function UPF0344 MLA2C4_06055 eb88fce93874f86646e0bf21e63702e8 122 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 121 4.0E-59 T 01-11-2018 IPR010899 Protein of unknown function UPF0344 MLA2C4_06055 eb88fce93874f86646e0bf21e63702e8 122 Pfam PF07457 Protein of unknown function (DUF1516) 2 111 3.8E-33 T 01-11-2018 IPR010899 Protein of unknown function UPF0344 MLA2C4_24245 7574aedb111abf78628055334e6f83e4 290 SUPERFAMILY SSF53474 9 282 3.33E-44 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24245 7574aedb111abf78628055334e6f83e4 290 Pfam PF00561 alpha/beta hydrolase fold 55 270 1.5E-18 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24245 7574aedb111abf78628055334e6f83e4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.0E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24245 7574aedb111abf78628055334e6f83e4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.0E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24245 7574aedb111abf78628055334e6f83e4 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 228 242 1.0E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 Pfam PF00158 Sigma-54 interaction domain 149 315 3.2E-66 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 SUPERFAMILY SSF55785 11 111 9.77E-13 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 SMART SM00382 168 312 1.5E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 Gene3D G3DSA:1.10.10.60 385 449 1.2E-5 T 01-11-2018 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 Gene3D G3DSA:1.10.8.60 320 384 9.0E-20 T 01-11-2018 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 SUPERFAMILY SSF52540 148 389 7.98E-65 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 Gene3D G3DSA:3.30.450.20 3 124 2.0E-15 T 01-11-2018 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 Gene3D G3DSA:3.40.50.300 133 319 1.5E-65 T 01-11-2018 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 124 5.0E-8 T 01-11-2018 IPR000014 PAS domain MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 SUPERFAMILY SSF46689 401 446 1.25E-6 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_01935 1a5f2e7c9d73ee3326fd2cf696ca5423 455 Pfam PF13426 PAS domain 23 117 4.1E-9 T 01-11-2018 IPR000014 PAS domain MLA2C4_01765 860dc9f928f1e3257506a5989358732a 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 1.0E-34 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01765 860dc9f928f1e3257506a5989358732a 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 21.182 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01765 860dc9f928f1e3257506a5989358732a 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 1.9E-31 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01765 860dc9f928f1e3257506a5989358732a 84 Gene3D G3DSA:3.30.1280.10 1 84 4.4E-36 T 01-11-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01765 860dc9f928f1e3257506a5989358732a 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 2.6E-31 T 01-11-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01765 860dc9f928f1e3257506a5989358732a 84 SUPERFAMILY SSF82697 1 80 1.48E-28 T 01-11-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 SUPERFAMILY SSF52540 5 254 9.8E-69 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 Gene3D G3DSA:3.40.50.300 3 326 1.3E-101 T 01-11-2018 MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 Pfam PF00005 ABC transporter 26 183 4.5E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 3.8E-28 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 2.2E-16 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01310 7e6417811ae56e5b1d84fcea4deaef12 326 SMART SM00382 34 233 2.6E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19440 5b2ee4d9058473421bf88eea55140d26 464 Gene3D G3DSA:1.20.1740.10 3 462 3.5E-73 T 01-11-2018 MLA2C4_19440 5b2ee4d9058473421bf88eea55140d26 464 PIRSF PIRSF006060 2 462 9.7E-79 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_19440 5b2ee4d9058473421bf88eea55140d26 464 Pfam PF00324 Amino acid permease 13 450 1.4E-118 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_19440 5b2ee4d9058473421bf88eea55140d26 464 TIGRFAM TIGR01773 GABAperm: GABA permease 4 447 4.8E-207 T 01-11-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 MLA2C4_19440 5b2ee4d9058473421bf88eea55140d26 464 ProSitePatterns PS00218 Amino acid permeases signature. 38 68 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_07165 aabcf2b4f3752b1287e3b4b02cac39fb 119 TIGRFAM TIGR00333 nrdI: nrdI protein 3 117 1.1E-39 T 01-11-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MLA2C4_07165 aabcf2b4f3752b1287e3b4b02cac39fb 119 PIRSF PIRSF005087 1 119 3.5E-41 T 01-11-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MLA2C4_07165 aabcf2b4f3752b1287e3b4b02cac39fb 119 Hamap MF_00128 Protein NrdI [nrdI]. 1 119 26.587 T 01-11-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial MLA2C4_07165 aabcf2b4f3752b1287e3b4b02cac39fb 119 Pfam PF07972 NrdI Flavodoxin like 3 110 4.9E-32 T 01-11-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MLA2C4_07165 aabcf2b4f3752b1287e3b4b02cac39fb 119 Gene3D G3DSA:3.40.50.360 1 119 5.3E-44 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_07165 aabcf2b4f3752b1287e3b4b02cac39fb 119 SUPERFAMILY SSF52218 2 117 8.38E-25 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 SUPERFAMILY SSF46955 2 104 2.78E-23 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 SMART SM00422 2 72 7.9E-14 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 SUPERFAMILY SSF55136 134 265 2.44E-12 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 Gene3D G3DSA:1.10.1660.10 1 122 1.3E-23 T 01-11-2018 MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.3E-13 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 Gene3D G3DSA:3.20.80.10 123 265 3.0E-17 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 Pfam PF06445 GyrI-like small molecule binding domain 198 265 6.8E-9 T 01-11-2018 IPR029442 GyrI-like small molecule binding domain MLA2C4_14190 28ea5270390cda57a374b8b20bd33cf0 265 SMART SM00871 123 265 1.6E-14 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 Gene3D G3DSA:3.50.30.80 374 523 1.1E-52 T 01-11-2018 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 SUPERFAMILY SSF143975 1 373 1.02E-139 T 01-11-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 01-11-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 Pfam PF00920 Dehydratase family 31 549 3.0E-227 T 01-11-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 01-11-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 552 4.7E-253 T 01-11-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 SUPERFAMILY SSF52016 374 552 2.82E-60 T 01-11-2018 MLA2C4_09460 fea4b8de6e35f32ee22f1e31f389d9dc 557 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 47.143 T 01-11-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 SUPERFAMILY SSF52540 201 758 1.82E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Gene3D G3DSA:3.40.50.300 605 775 1.6E-56 T 01-11-2018 MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Pfam PF13361 UvrD-like helicase C-terminal domain 602 689 2.8E-6 T 01-11-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Pfam PF13538 UvrD-like helicase C-terminal domain 706 753 6.3E-8 T 01-11-2018 IPR027785 UvrD-like helicase C-terminal domain MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Gene3D G3DSA:3.40.50.300 200 344 5.3E-9 T 01-11-2018 MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Gene3D G3DSA:1.10.10.160 482 516 2.1E-8 T 01-11-2018 IPR013986 DExx box DNA helicase domain superfamily MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Pfam PF13245 AAA domain 214 579 4.9E-11 T 01-11-2018 MLA2C4_05545 d0fee229b6455f0e89d4a2b9cc98ed63 776 Gene3D G3DSA:3.40.50.300 517 581 2.1E-8 T 01-11-2018 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 SUPERFAMILY SSF53649 2 508 2.09E-74 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 Gene3D G3DSA:3.40.1450.10 76 311 1.3E-237 T 01-11-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 SUPERFAMILY SSF64158 76 309 1.83E-92 T 01-11-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 Gene3D G3DSA:3.40.720.10 4 506 1.3E-237 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 3 508 7.8E-212 T 01-11-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 3 509 49.883 T 01-11-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 81 298 8.8E-85 T 01-11-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 Pfam PF01676 Metalloenzyme superfamily 3 497 5.8E-77 T 01-11-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 MLA2C4_26570 e0f7276bd842ea5fa9138cf7fdfe3830 509 PIRSF PIRSF001492 1 509 3.1E-206 T 01-11-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MLA2C4_15460 d909d94d2cbbf1a377579e9427d521c1 157 SUPERFAMILY SSF48452 17 129 1.48E-13 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_15460 d909d94d2cbbf1a377579e9427d521c1 157 Pfam PF12688 Tetratrico peptide repeat 36 151 1.2E-14 T 01-11-2018 MLA2C4_15460 d909d94d2cbbf1a377579e9427d521c1 157 SMART SM00028 34 67 160.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_15460 d909d94d2cbbf1a377579e9427d521c1 157 SMART SM00028 71 104 0.0064 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_15460 d909d94d2cbbf1a377579e9427d521c1 157 Gene3D G3DSA:1.25.40.10 45 150 7.3E-19 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.7E-9 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.7E-9 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.7E-9 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 Gene3D G3DSA:1.10.1660.10 1 121 5.3E-26 T 01-11-2018 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 SMART SM00422 1 69 2.1E-18 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 Pfam PF13411 MerR HTH family regulatory protein 2 68 3.7E-16 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_26780 7916b03edfe4fbda4a056c9950b7aa54 122 SUPERFAMILY SSF46955 1 116 1.54E-22 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 SUPERFAMILY SSF55681 104 460 2.11E-100 T 01-11-2018 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 457 1.5E-89 T 01-11-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 SUPERFAMILY SSF50249 13 102 1.31E-19 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 Gene3D G3DSA:3.30.930.10 106 461 1.8E-117 T 01-11-2018 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 378 394 2.9E-12 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 418 432 2.9E-12 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 217 2.9E-12 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 221 234 2.9E-12 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 463 46.397 T 01-11-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 Pfam PF01336 OB-fold nucleic acid binding domain 21 97 1.4E-10 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 Gene3D G3DSA:2.40.50.140 2 105 2.4E-22 T 01-11-2018 MLA2C4_23690 e452c81dd4185a582d0998b28dc08e97 463 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 463 1.6E-191 T 01-11-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 Gene3D G3DSA:1.10.10.10 1 84 4.9E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 Gene3D G3DSA:3.30.450.40 104 333 1.4E-57 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 SUPERFAMILY SSF55781 71 336 7.45E-67 T 01-11-2018 MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 32.685 T 01-11-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 PIRSF PIRSF005485 1 338 8.6E-125 T 01-11-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 Pfam PF01628 HrcA protein C terminal domain 104 322 7.4E-63 T 01-11-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 SUPERFAMILY SSF46785 1 82 3.24E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 332 7.7E-113 T 01-11-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 MLA2C4_22540 87c40d1a2150b2fe704b0aaf48337967 338 Gene3D G3DSA:3.30.390.60 128 229 1.4E-57 T 01-11-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily MLA2C4_12450 83e981063e6fd0b7efb5a02504a6c7dd 183 Gene3D G3DSA:3.40.630.30 2 182 4.1E-42 T 01-11-2018 MLA2C4_12450 83e981063e6fd0b7efb5a02504a6c7dd 183 SUPERFAMILY SSF55729 3 174 1.23E-44 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12450 83e981063e6fd0b7efb5a02504a6c7dd 183 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 3.2E-25 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10175 d929430370c91c1a1df9193292ee2f54 95 Gene3D G3DSA:2.10.260.10 1 54 4.4E-25 T 01-11-2018 MLA2C4_10175 d929430370c91c1a1df9193292ee2f54 95 SMART SM00966 8 51 4.4E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_10175 d929430370c91c1a1df9193292ee2f54 95 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 49 1.7E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_10175 d929430370c91c1a1df9193292ee2f54 95 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 48 1.6E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_10175 d929430370c91c1a1df9193292ee2f54 95 SUPERFAMILY SSF89447 1 51 4.84E-16 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily MLA2C4_25035 e02f341fc605feeeba982b630b9cff99 75 Pfam PF04023 FeoA domain 1 73 5.3E-15 T 01-11-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MLA2C4_25035 e02f341fc605feeeba982b630b9cff99 75 SUPERFAMILY SSF50037 3 73 7.32E-15 T 01-11-2018 IPR008988 Transcriptional repressor, C-terminal MLA2C4_25035 e02f341fc605feeeba982b630b9cff99 75 Gene3D G3DSA:2.30.30.90 1 75 2.0E-17 T 01-11-2018 IPR038157 Ferrous iron transporter, core domain MLA2C4_25035 e02f341fc605feeeba982b630b9cff99 75 SMART SM00899 1 74 2.1E-17 T 01-11-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MLA2C4_20250 295e240864079a2c7aa403ee9566f553 569 Gene3D G3DSA:1.10.8.50 168 235 2.3E-26 T 01-11-2018 MLA2C4_20250 295e240864079a2c7aa403ee9566f553 569 Gene3D G3DSA:3.40.970.40 243 290 1.8E-17 T 01-11-2018 MLA2C4_20250 295e240864079a2c7aa403ee9566f553 569 Gene3D G3DSA:2.30.310.10 1 167 1.2E-67 T 01-11-2018 MLA2C4_20250 295e240864079a2c7aa403ee9566f553 569 Pfam PF05670 Domain of unknown function (DUF814) 455 538 2.6E-27 T 01-11-2018 IPR008532 Domain of unknown function DUF814 MLA2C4_20250 295e240864079a2c7aa403ee9566f553 569 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 1.7E-162 T 01-11-2018 MLA2C4_03650 c766bc6d680de6ed2cfdb682d7f97fe3 463 PIRSF PIRSF006060 1 461 3.8E-74 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_03650 c766bc6d680de6ed2cfdb682d7f97fe3 463 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_03650 c766bc6d680de6ed2cfdb682d7f97fe3 463 Pfam PF00324 Amino acid permease 18 448 2.5E-119 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_03650 c766bc6d680de6ed2cfdb682d7f97fe3 463 Gene3D G3DSA:1.20.1740.10 10 460 1.8E-66 T 01-11-2018 MLA2C4_25155 1c2570115b30433824744f437fa25d4a 211 Pfam PF13630 SdpI/YhfL protein family 133 200 1.1E-22 T 01-11-2018 IPR025962 SdpI/YhfL protein family MLA2C4_25155 1c2570115b30433824744f437fa25d4a 211 PIRSF PIRSF038959 1 211 4.2E-52 T 01-11-2018 IPR026272 Immunity protein SdpI MLA2C4_25155 1c2570115b30433824744f437fa25d4a 211 Pfam PF07853 Protein of unknown function (DUF1648) 9 56 3.7E-14 T 01-11-2018 IPR012867 Domain of unknown function DUF1648 MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 Pfam PF02565 Recombination protein O C terminal 82 238 7.8E-34 T 01-11-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 Gene3D G3DSA:3.30.60.100 146 185 1.0E-15 T 01-11-2018 MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 Pfam PF11967 Recombination protein O N terminal 1 77 6.5E-26 T 01-11-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 Gene3D G3DSA:1.20.1440.120 88 225 1.0E-15 T 01-11-2018 MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 SUPERFAMILY SSF50249 1 77 8.39E-20 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 SUPERFAMILY SSF57863 80 231 1.57E-44 T 01-11-2018 IPR037278 ARFGAP/RecO-like zinc finger MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 Gene3D G3DSA:2.40.50.140 2 81 5.0E-16 T 01-11-2018 MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 1.0E-75 T 01-11-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MLA2C4_22450 767a68246f447a708d0eef53706805fd 248 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 28.82 T 01-11-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MLA2C4_07460 079736ca07d466496e8e859d4c7269b4 101 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 101 28.637 T 01-11-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MLA2C4_07460 079736ca07d466496e8e859d4c7269b4 101 SUPERFAMILY SSF141734 6 99 1.06E-44 T 01-11-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MLA2C4_07460 079736ca07d466496e8e859d4c7269b4 101 Gene3D G3DSA:3.10.20.400 1 88 1.4E-38 T 01-11-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MLA2C4_07460 079736ca07d466496e8e859d4c7269b4 101 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 47 101 4.0E-27 T 01-11-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MLA2C4_07460 079736ca07d466496e8e859d4c7269b4 101 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 24 97 2.7E-35 T 01-11-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 Pfam PF01726 LexA DNA binding domain 1 65 1.3E-30 T 01-11-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 TIGRFAM TIGR00498 lexA: repressor LexA 1 205 1.2E-79 T 01-11-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 Pfam PF00717 Peptidase S24-like 123 187 6.5E-17 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 SUPERFAMILY SSF46785 3 70 2.09E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 SUPERFAMILY SSF51306 82 204 1.66E-36 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 Gene3D G3DSA:1.10.10.10 3 68 3.0E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 Gene3D G3DSA:2.10.109.10 88 205 1.5E-41 T 01-11-2018 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 131 142 2.7E-12 T 01-11-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 160 172 2.7E-12 T 01-11-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 120 130 2.7E-12 T 01-11-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MLA2C4_19205 e45f34e62aa789324452bd0e76c03a49 206 Hamap MF_00015 LexA repressor [lexA]. 3 205 35.65 T 01-11-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 Pfam PF13411 MerR HTH family regulatory protein 7 76 2.0E-16 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 SUPERFAMILY SSF55136 124 274 7.5E-44 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 Gene3D G3DSA:3.20.80.10 198 276 3.9E-14 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 SUPERFAMILY SSF46955 6 113 3.0E-25 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 SMART SM00871 123 274 2.9E-11 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 Pfam PF06445 GyrI-like small molecule binding domain 162 273 9.6E-12 T 01-11-2018 IPR029442 GyrI-like small molecule binding domain MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 Gene3D G3DSA:1.10.1660.10 4 141 4.4E-29 T 01-11-2018 MLA2C4_08425 fda9bac9a677e0895c4ba43928ca5c63 281 SMART SM00422 7 77 4.9E-14 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_02660 7a709ad24e2dc08321e66efb4ec7f60c 39 Pfam PF14152 YfhE-like protein 2 37 5.0E-20 T 01-11-2018 IPR025437 YfhE-like protein MLA2C4_25630 132b75285f146210c9a47627e78594e7 168 Pfam PF00293 NUDIX domain 9 117 1.5E-16 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_25630 132b75285f146210c9a47627e78594e7 168 SUPERFAMILY SSF55811 6 129 3.79E-26 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_25630 132b75285f146210c9a47627e78594e7 168 PRINTS PR00502 NUDIX hydrolase family signature 36 50 2.7E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_25630 132b75285f146210c9a47627e78594e7 168 PRINTS PR00502 NUDIX hydrolase family signature 50 65 2.7E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_25630 132b75285f146210c9a47627e78594e7 168 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_25630 132b75285f146210c9a47627e78594e7 168 Gene3D G3DSA:3.90.79.10 7 147 6.0E-25 T 01-11-2018 MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 PIRSF PIRSF000139 5 441 8.3E-161 T 01-11-2018 MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 SUPERFAMILY SSF46548 9 105 2.27E-19 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 Pfam PF13183 4Fe-4S dicluster domain 22 91 2.0E-12 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 Pfam PF02754 Cysteine-rich domain 328 413 6.8E-14 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 Pfam PF02754 Cysteine-rich domain 197 277 1.4E-19 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 Gene3D G3DSA:1.10.1060.10 2 112 2.7E-8 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_06890 9092e5a3b0728a0c41c170f5bc0221aa 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_04160 bc690548fec906db24d9a2305f343d00 517 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 7 477 9.5E-129 T 01-11-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MLA2C4_04160 bc690548fec906db24d9a2305f343d00 517 Gene3D G3DSA:3.90.1640.30 25 286 8.9E-76 T 01-11-2018 MLA2C4_04160 bc690548fec906db24d9a2305f343d00 517 Pfam PF02272 DHHA1 domain 287 394 3.6E-10 T 01-11-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MLA2C4_04160 bc690548fec906db24d9a2305f343d00 517 Gene3D G3DSA:3.10.310.30 289 411 1.0E-27 T 01-11-2018 MLA2C4_04160 bc690548fec906db24d9a2305f343d00 517 Pfam PF01368 DHH family 52 181 1.8E-11 T 01-11-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_04160 bc690548fec906db24d9a2305f343d00 517 SUPERFAMILY SSF64182 27 407 5.89E-90 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily MLA2C4_14810 44d7f2a6022dda1d6e015117ae053bfe 172 Gene3D G3DSA:3.40.50.300 1 169 1.1E-17 T 01-11-2018 MLA2C4_14810 44d7f2a6022dda1d6e015117ae053bfe 172 SUPERFAMILY SSF52540 1 99 9.72E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_16765 a434609d1ddb35ef89639120e3abfddb 346 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 4 333 1.6E-142 T 01-11-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MLA2C4_16765 a434609d1ddb35ef89639120e3abfddb 346 PIRSF PIRSF005508 1 346 1.6E-140 T 01-11-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MLA2C4_16765 a434609d1ddb35ef89639120e3abfddb 346 Gene3D G3DSA:1.20.1530.20 1 339 4.6E-27 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_16765 a434609d1ddb35ef89639120e3abfddb 346 Pfam PF01758 Sodium Bile acid symporter family 49 245 6.8E-68 T 01-11-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MLA2C4_24015 6243c98a78eebdcac866d6baa3190062 87 Pfam PF12844 Helix-turn-helix domain 21 80 1.7E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_24015 6243c98a78eebdcac866d6baa3190062 87 Gene3D G3DSA:1.10.260.40 17 81 2.6E-25 T 01-11-2018 MLA2C4_24015 6243c98a78eebdcac866d6baa3190062 87 SMART SM00530 21 76 4.5E-11 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_24015 6243c98a78eebdcac866d6baa3190062 87 SUPERFAMILY SSF47413 18 80 3.66E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_01580 f62b0bca69c4882f060195317ba6b50b 409 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 88 1.4E-22 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_01580 f62b0bca69c4882f060195317ba6b50b 409 Pfam PF06013 Proteins of 100 residues with WXG 3 88 5.4E-19 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_01580 f62b0bca69c4882f060195317ba6b50b 409 Gene3D G3DSA:1.10.287.850 1 96 1.4E-25 T 01-11-2018 MLA2C4_01580 f62b0bca69c4882f060195317ba6b50b 409 SUPERFAMILY SSF140453 3 90 4.32E-17 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_01580 f62b0bca69c4882f060195317ba6b50b 409 PIRSF PIRSF038601 1 408 2.5E-186 T 01-11-2018 IPR024696 Uncharacterised conserved protein, UCP038601 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 10 465 1.1E-178 T 01-11-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 Gene3D G3DSA:3.20.140.10 11 470 5.4E-205 T 01-11-2018 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 336 6.5E-13 T 01-11-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 Gene3D G3DSA:3.20.20.70 151 318 5.4E-205 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 SUPERFAMILY SSF54675 5 138 3.36E-48 T 01-11-2018 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 PIRSF PIRSF000484 3 480 2.4E-158 T 01-11-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MLA2C4_03160 4eee8aa2c5b0f5bdc6be9f4cfdaccf86 487 SUPERFAMILY SSF51690 139 478 1.91E-132 T 01-11-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MLA2C4_25330 a6bb5ce6f892ce44761960fb0cb13b3e 201 Pfam PF12389 Camelysin metallo-endopeptidase 2 199 2.5E-83 T 01-11-2018 IPR022121 Peptidase M73, camelysin MLA2C4_25330 a6bb5ce6f892ce44761960fb0cb13b3e 201 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 44 1.9E-10 T 01-11-2018 IPR023833 Signal peptide, camelysin MLA2C4_12765 b82189f42d3e42466802852903f4d0b0 299 Gene3D G3DSA:3.30.420.40 5 285 3.8E-63 T 01-11-2018 MLA2C4_12765 b82189f42d3e42466802852903f4d0b0 299 SUPERFAMILY SSF53067 1 105 1.02E-19 T 01-11-2018 MLA2C4_12765 b82189f42d3e42466802852903f4d0b0 299 SUPERFAMILY SSF53067 110 296 6.57E-40 T 01-11-2018 MLA2C4_12765 b82189f42d3e42466802852903f4d0b0 299 Gene3D G3DSA:3.30.420.40 109 279 3.8E-63 T 01-11-2018 MLA2C4_12765 b82189f42d3e42466802852903f4d0b0 299 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 284 1.3E-20 T 01-11-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 Gene3D G3DSA:1.10.10.10 1 89 6.9E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.9E-18 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-8 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 SUPERFAMILY SSF53850 87 295 3.39E-43 T 01-11-2018 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 Pfam PF03466 LysR substrate binding domain 87 292 1.5E-47 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 Gene3D G3DSA:3.40.190.10 165 266 1.0E-41 T 01-11-2018 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 Gene3D G3DSA:3.40.190.10 90 288 1.0E-41 T 01-11-2018 MLA2C4_18105 020e70313d7df7be721881bc42690dda 297 SUPERFAMILY SSF46785 1 84 6.81E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_09780 a0bdbf811f703216fbc844d5ba6bc6a6 330 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 29 207 3.5E-45 T 01-11-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MLA2C4_09780 a0bdbf811f703216fbc844d5ba6bc6a6 330 SUPERFAMILY SSF52540 18 286 2.12E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09780 a0bdbf811f703216fbc844d5ba6bc6a6 330 Gene3D G3DSA:3.40.50.300 24 222 2.2E-50 T 01-11-2018 MLA2C4_09780 a0bdbf811f703216fbc844d5ba6bc6a6 330 Gene3D G3DSA:3.30.1220.10 223 326 1.2E-10 T 01-11-2018 IPR036627 CobW-like, C-terminal domain superfamily MLA2C4_09780 a0bdbf811f703216fbc844d5ba6bc6a6 330 SMART SM00833 241 326 4.5E-18 T 01-11-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MLA2C4_09780 a0bdbf811f703216fbc844d5ba6bc6a6 330 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 241 324 2.5E-15 T 01-11-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 Pfam PF04545 Sigma-70, region 4 104 152 3.3E-7 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 Gene3D G3DSA:1.20.140.160 71 155 3.5E-8 T 01-11-2018 MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 SUPERFAMILY SSF88946 7 72 3.27E-11 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 Pfam PF04542 Sigma-70 region 2 25 74 9.6E-10 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 SUPERFAMILY SSF88659 93 155 6.54E-12 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 Gene3D G3DSA:1.10.1740.10 7 70 4.0E-7 T 01-11-2018 MLA2C4_27160 40709ec3202397d110ead175e62e0052 156 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 153 9.6E-20 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 SMART SM00287 286 347 1.5E-7 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 SMART SM00287 202 264 4.9E-11 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 SMART SM00287 371 432 4.7E-14 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 SMART SM00287 46 107 1.2E-8 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 SMART SM00287 118 179 9.7E-13 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Pfam PF08239 Bacterial SH3 domain 295 344 9.3E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Pfam PF08239 Bacterial SH3 domain 127 177 3.4E-14 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Pfam PF08239 Bacterial SH3 domain 210 260 1.2E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Pfam PF08239 Bacterial SH3 domain 54 105 6.0E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Pfam PF08239 Bacterial SH3 domain 379 430 1.1E-13 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 SUPERFAMILY SSF54001 461 581 5.23E-32 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Pfam PF00877 NlpC/P60 family 478 579 4.1E-25 T 01-11-2018 IPR000064 Endopeptidase, NLPC/P60 domain MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Gene3D G3DSA:2.30.30.40 373 429 4.1E-18 T 01-11-2018 MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Gene3D G3DSA:2.30.30.40 120 186 1.4E-15 T 01-11-2018 MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Gene3D G3DSA:2.30.30.40 286 344 1.4E-15 T 01-11-2018 MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Gene3D G3DSA:2.30.30.40 203 260 1.1E-17 T 01-11-2018 MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Gene3D G3DSA:3.90.1720.10 430 577 7.9E-34 T 01-11-2018 MLA2C4_27070 350a8d285b15eb644e509696115e961c 583 Gene3D G3DSA:2.30.30.40 36 107 1.2E-16 T 01-11-2018 MLA2C4_22620 a31bb9f08a6d5fc3bb81abcdcaf4663c 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 4.3E-56 T 01-11-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MLA2C4_22620 a31bb9f08a6d5fc3bb81abcdcaf4663c 189 SUPERFAMILY SSF52374 3 187 1.78E-50 T 01-11-2018 MLA2C4_22620 a31bb9f08a6d5fc3bb81abcdcaf4663c 189 Pfam PF01467 Cytidylyltransferase-like 6 162 9.6E-32 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MLA2C4_22620 a31bb9f08a6d5fc3bb81abcdcaf4663c 189 Gene3D G3DSA:3.40.50.620 1 188 1.8E-64 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_22620 a31bb9f08a6d5fc3bb81abcdcaf4663c 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 31.086 T 01-11-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MLA2C4_22620 a31bb9f08a6d5fc3bb81abcdcaf4663c 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 1.8E-11 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MLA2C4_06505 71a595b32071ee7605e04cf04360ef99 253 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 251 33.058 T 01-11-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MLA2C4_06505 71a595b32071ee7605e04cf04360ef99 253 SUPERFAMILY SSF51366 3 248 2.83E-75 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_06505 71a595b32071ee7605e04cf04360ef99 253 Gene3D G3DSA:3.20.20.70 1 251 3.8E-92 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_06505 71a595b32071ee7605e04cf04360ef99 253 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 44 62 - T 01-11-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MLA2C4_06505 71a595b32071ee7605e04cf04360ef99 253 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 246 1.6E-82 T 01-11-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 Gene3D G3DSA:3.40.50.970 359 553 5.2E-58 T 01-11-2018 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 SUPERFAMILY SSF52467 169 340 1.35E-37 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 Gene3D G3DSA:3.40.50.970 1 187 1.4E-81 T 01-11-2018 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 SUPERFAMILY SSF52518 8 183 5.4E-45 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 SUPERFAMILY SSF52518 368 555 3.93E-42 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 205 322 1.6E-27 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 538 3.0E-18 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 PIRSF PIRSF036565 3 561 3.1E-220 T 01-11-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 182 3.2E-36 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MLA2C4_13260 2a021175d2e411095cd934e7674fadd0 561 Gene3D G3DSA:3.40.50.1220 192 350 1.8E-50 T 01-11-2018 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.7E-22 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 Gene3D G3DSA:1.10.10.10 1 90 2.2E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 SUPERFAMILY SSF53850 91 286 1.45E-28 T 01-11-2018 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.3E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.3E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.3E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 Gene3D G3DSA:3.40.190.290 91 289 6.1E-30 T 01-11-2018 MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 SUPERFAMILY SSF46785 1 85 5.44E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_16515 80ff32ce426cf27e4b5e602d2a68446c 292 Pfam PF03466 LysR substrate binding domain 91 284 1.4E-29 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_14370 169632514c55b4b60bcd6099125274a6 126 Pfam PF01541 GIY-YIG catalytic domain 45 119 7.1E-12 T 01-11-2018 IPR000305 GIY-YIG endonuclease MLA2C4_14370 169632514c55b4b60bcd6099125274a6 126 SMART SM00465 45 124 9.6E-15 T 01-11-2018 IPR000305 GIY-YIG endonuclease MLA2C4_14370 169632514c55b4b60bcd6099125274a6 126 Gene3D G3DSA:3.40.1440.10 39 124 1.8E-13 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_14370 169632514c55b4b60bcd6099125274a6 126 SUPERFAMILY SSF82771 44 122 2.22E-13 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_14370 169632514c55b4b60bcd6099125274a6 126 PIRSF PIRSF026568 1 126 5.3E-81 T 01-11-2018 IPR014527 Excinuclease GIY-YIG catalytic domain-containing uncharacterised conserved protein MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 111 6.1E-10 T 01-11-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 192 209 2.9E-6 T 01-11-2018 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 87 99 2.9E-6 T 01-11-2018 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 2.9E-6 T 01-11-2018 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 Gene3D G3DSA:2.60.40.420 117 282 1.1E-40 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 SUPERFAMILY SSF81464 19 120 8.67E-23 T 01-11-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 PIRSF PIRSF000292 2 291 3.3E-103 T 01-11-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 Gene3D G3DSA:1.10.287.90 29 116 1.6E-29 T 01-11-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 16 241 5.4E-91 T 01-11-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 MLA2C4_03700 577356b5e16189a2b35ca38fe1aaf1f4 291 SUPERFAMILY SSF49503 128 274 3.18E-42 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 SMART SM00422 2 71 1.7E-23 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 Gene3D G3DSA:1.10.1660.10 1 139 6.3E-33 T 01-11-2018 MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 4.1E-5 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 4.1E-5 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 4.1E-5 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 SUPERFAMILY SSF46955 3 105 3.44E-27 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_17375 7213f1d42b47ae73707c389fefe45f16 252 Pfam PF13411 MerR HTH family regulatory protein 4 69 3.2E-20 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 201 2.4E-40 T 01-11-2018 IPR003111 Lon, substrate-binding domain MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 01-11-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 SUPERFAMILY SSF52540 314 588 4.95E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 SMART SM00464 10 202 1.5E-68 T 01-11-2018 IPR003111 Lon, substrate-binding domain MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 3.9E-24 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 SUPERFAMILY SSF54211 595 770 1.4E-55 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Gene3D G3DSA:1.10.8.60 492 584 3.6E-33 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 SUPERFAMILY SSF88697 11 201 1.42E-44 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Gene3D G3DSA:3.30.230.10 593 776 1.3E-84 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 SMART SM00382 348 493 1.0E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Gene3D G3DSA:3.40.50.300 314 491 1.6E-69 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 5.4E-98 T 01-11-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Gene3D G3DSA:1.20.58.1480 120 245 2.9E-41 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 01-11-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 6.3E-53 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 6.3E-53 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 6.3E-53 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 6.3E-53 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 6.3E-53 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 PIRSF PIRSF001174 1 775 0.0 T 01-11-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Gene3D G3DSA:2.30.130.40 5 117 5.8E-30 T 01-11-2018 MLA2C4_23300 fb03bf10ee6a820e73a7385e5fae47f8 776 Hamap MF_01973 Lon protease [lon]. 11 772 72.764 T 01-11-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 629 8.8E-30 T 01-11-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Pfam PF01751 Toprim domain 423 523 9.3E-16 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 SUPERFAMILY SSF55874 7 219 1.57E-69 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 SUPERFAMILY SSF56719 398 633 2.88E-85 T 01-11-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 6 638 48.512 T 01-11-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 176 1.2E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 72 85 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 114 128 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 572 588 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 424 438 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 508 525 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 528 540 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 37 52 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 490 506 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR00418 DNA topoisomerase II family signature 268 281 2.2E-69 T 01-11-2018 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 7 642 0.0 T 01-11-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Gene3D G3DSA:3.40.50.670 410 642 5.0E-101 T 01-11-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 SUPERFAMILY SSF54211 222 392 8.54E-55 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Gene3D G3DSA:3.30.230.10 221 402 2.6E-73 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Gene3D G3DSA:3.30.565.10 5 220 3.3E-87 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 SMART SM00433 37 633 0.0 T 01-11-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 Pfam PF00204 DNA gyrase B 222 392 1.7E-58 T 01-11-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 474 483 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 609 625 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 182 197 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 593 605 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 376 396 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 8 18 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 362 376 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 221 243 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 312 328 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 PRINTS PR01159 DNA gyrase subunit B signature 197 210 2.2E-60 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 01-11-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18685 1a2c17fc46ea21574dc85d4db02e3f6d 654 SMART SM00387 33 177 2.7E-25 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.4E-8 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.4E-8 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.4E-8 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 SUPERFAMILY SSF54909 64 137 1.02E-8 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 SMART SM00344 2 109 4.2E-28 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 Pfam PF01037 Lrp/AsnC ligand binding domain 75 135 6.6E-6 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 SUPERFAMILY SSF46785 2 60 8.2E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 Gene3D G3DSA:1.10.10.10 1 51 2.6E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 Gene3D G3DSA:3.30.70.920 52 142 2.8E-13 T 01-11-2018 MLA2C4_26455 c55d87427b24cf01fa7452431371b53a 142 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 9.7E-15 T 01-11-2018 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Gene3D G3DSA:3.40.50.300 397 569 0.0 T 01-11-2018 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Pfam PF07516 SecA Wing and Scaffold domain 567 776 1.9E-64 T 01-11-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 SUPERFAMILY SSF81886 570 823 3.92E-80 T 01-11-2018 IPR036266 SecA, Wing/Scaffold superfamily MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Gene3D G3DSA:1.10.1200.230 620 703 0.0 T 01-11-2018 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 99 113 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 115 125 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 168 188 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 61 85 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 393 406 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 319 341 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 PRINTS PR00906 SecA protein signature 356 373 3.1E-72 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Gene3D G3DSA:1.10.3060.10 570 775 0.0 T 01-11-2018 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 SUPERFAMILY SSF81767 225 348 9.29E-48 T 01-11-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 779 19.646 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 SMART SM00957 5 382 3.7E-287 T 01-11-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 01-11-2018 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 ProSitePatterns PS01312 SecA family signature. 480 495 - T 01-11-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Pfam PF01043 SecA preprotein cross-linking domain 230 338 6.4E-41 T 01-11-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Pfam PF00271 Helicase conserved C-terminal domain 419 529 5.0E-5 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Pfam PF07517 SecA DEAD-like domain 6 382 2.2E-130 T 01-11-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 499 4.3E-242 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Pfam PF02810 SEC-C motif 815 832 4.6E-8 T 01-11-2018 IPR004027 SEC-C motif MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 01-11-2018 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 SMART SM00958 226 338 5.3E-65 T 01-11-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 SUPERFAMILY SSF52540 5 395 5.18E-85 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26840 b5d44b60e28dcf9d8811bb3039e265da 835 SUPERFAMILY SSF52540 398 568 2.37E-50 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_16725 8d96b3558f5e01d99ea56915ce9eea5d 210 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 206 1.1E-50 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_16725 8d96b3558f5e01d99ea56915ce9eea5d 210 SMART SM01207 12 198 2.3E-71 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_16725 8d96b3558f5e01d99ea56915ce9eea5d 210 Pfam PF02660 Glycerol-3-phosphate acyltransferase 13 197 2.6E-50 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_16725 8d96b3558f5e01d99ea56915ce9eea5d 210 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 9 206 18.718 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_19395 485f227976628295bb947ccf52108c97 317 Pfam PF01715 IPP transferase 42 286 1.7E-84 T 01-11-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MLA2C4_19395 485f227976628295bb947ccf52108c97 317 SUPERFAMILY SSF52540 11 266 2.46E-5 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19395 485f227976628295bb947ccf52108c97 317 Gene3D G3DSA:3.40.50.300 13 291 2.5E-107 T 01-11-2018 MLA2C4_19395 485f227976628295bb947ccf52108c97 317 Gene3D G3DSA:1.10.20.140 116 188 2.5E-107 T 01-11-2018 MLA2C4_19395 485f227976628295bb947ccf52108c97 317 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 303 30.546 T 01-11-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MLA2C4_19395 485f227976628295bb947ccf52108c97 317 SUPERFAMILY SSF52540 10 163 1.03E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19395 485f227976628295bb947ccf52108c97 317 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 294 4.5E-115 T 01-11-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MLA2C4_02020 88cab7b50394de57787a9ce05f7d856a 202 Pfam PF13679 Methyltransferase domain 43 102 2.6E-7 T 01-11-2018 IPR025714 Methyltransferase domain MLA2C4_02020 88cab7b50394de57787a9ce05f7d856a 202 Gene3D G3DSA:3.40.50.150 24 182 5.3E-16 T 01-11-2018 MLA2C4_02020 88cab7b50394de57787a9ce05f7d856a 202 SUPERFAMILY SSF53335 4 140 1.28E-17 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 SUPERFAMILY SSF51182 54 171 4.9E-21 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 SUPERFAMILY SSF47413 1 67 2.53E-16 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 Pfam PF12844 Helix-turn-helix domain 4 62 3.3E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 Pfam PF07883 Cupin domain 102 169 8.0E-13 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 SMART SM00530 6 61 5.0E-13 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 Gene3D G3DSA:1.10.260.40 1 68 7.4E-17 T 01-11-2018 MLA2C4_22755 b43115ce80af9bb646185bbbe4c612c2 181 Gene3D G3DSA:2.60.120.10 69 171 3.3E-14 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_25590 d276a3058325d3b403309c9b5e332232 197 Pfam PF02632 BioY family 36 180 4.7E-29 T 01-11-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 MLA2C4_25590 d276a3058325d3b403309c9b5e332232 197 PIRSF PIRSF016661 1 190 4.0E-41 T 01-11-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 MLA2C4_25590 d276a3058325d3b403309c9b5e332232 197 Gene3D G3DSA:1.10.1760.20 1 187 1.2E-42 T 01-11-2018 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 657 44.926 T 01-11-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 SUPERFAMILY SSF52540 4 414 6.85E-143 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Gene3D G3DSA:3.40.50.300 1 243 3.0E-83 T 01-11-2018 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Gene3D G3DSA:3.40.50.300 414 595 2.5E-53 T 01-11-2018 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 SUPERFAMILY SSF52540 32 593 3.38E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 SUPERFAMILY SSF46600 613 656 7.19E-10 T 01-11-2018 IPR036876 UVR domain superfamily MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 SMART SM00487 9 425 5.3E-25 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Pfam PF12344 Ultra-violet resistance protein B 551 592 1.4E-22 T 01-11-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Pfam PF02151 UvrB/uvrC motif 622 656 4.8E-9 T 01-11-2018 IPR001943 UVR domain GO:0005515 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Pfam PF00271 Helicase conserved C-terminal domain 440 544 6.0E-19 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 SMART SM00490 459 545 2.9E-20 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Gene3D G3DSA:3.40.50.300 263 413 2.3E-54 T 01-11-2018 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 655 0.0 T 01-11-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Gene3D G3DSA:4.10.860.10 604 657 1.0E-5 T 01-11-2018 MLA2C4_26725 cd8fba1e32cb8301fe3b2c3cbb286017 658 Pfam PF04851 Type III restriction enzyme, res subunit 16 115 5.0E-10 T 01-11-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 SMART SM00448 1 111 3.9E-42 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 Pfam PF00072 Response regulator receiver domain 4 112 1.8E-26 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 2.4E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 SUPERFAMILY SSF52172 1 124 1.07E-39 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 Gene3D G3DSA:3.40.50.2300 1 127 7.3E-37 T 01-11-2018 MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 SUPERFAMILY SSF46894 123 221 7.09E-25 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 Gene3D G3DSA:1.10.10.10 128 223 9.7E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03040 3f13dc0feb75f639afac4c02c5ffdfea 223 SMART SM00862 145 220 2.4E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_04775 c5d54f48cffb3ddf4bd6d106c1c06f58 293 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 39 161 4.4E-37 T 01-11-2018 IPR030910 SLAP domain, Bacillus-type MLA2C4_04775 c5d54f48cffb3ddf4bd6d106c1c06f58 293 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 168 290 1.8E-43 T 01-11-2018 IPR030910 SLAP domain, Bacillus-type MLA2C4_04775 c5d54f48cffb3ddf4bd6d106c1c06f58 293 TIGRFAM TIGR04399 acc_Sec_SLAP: accessory Sec system S-layer assembly protein 4 292 6.1E-128 T 01-11-2018 IPR030911 Accessory Sec system S-layer assembly protein MLA2C4_08345 f87fd86a0c204982645d239116a01cf2 290 Pfam PF01263 Aldose 1-epimerase 2 285 1.4E-33 T 01-11-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MLA2C4_08345 f87fd86a0c204982645d239116a01cf2 290 Gene3D G3DSA:2.70.98.10 2 290 5.4E-107 T 01-11-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MLA2C4_08345 f87fd86a0c204982645d239116a01cf2 290 SUPERFAMILY SSF74650 4 289 2.32E-56 T 01-11-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MLA2C4_04625 4b328b82c792c6d65b48679ba0175da0 474 PIRSF PIRSF006060 1 474 7.8E-57 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_04625 4b328b82c792c6d65b48679ba0175da0 474 Pfam PF13520 Amino acid permease 7 430 2.3E-54 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_04625 4b328b82c792c6d65b48679ba0175da0 474 Gene3D G3DSA:1.20.1740.10 1 474 3.1E-65 T 01-11-2018 MLA2C4_24420 ec426061f0a7848d55f4284ff1bcb253 169 Gene3D G3DSA:3.90.950.10 1 168 1.4E-49 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MLA2C4_24420 ec426061f0a7848d55f4284ff1bcb253 169 SUPERFAMILY SSF52972 1 165 2.49E-48 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MLA2C4_24420 ec426061f0a7848d55f4284ff1bcb253 169 Pfam PF01931 Protein of unknown function DUF84 6 156 9.7E-45 T 01-11-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.8E-19 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-7 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-7 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-7 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 Gene3D G3DSA:3.40.190.290 92 291 3.0E-33 T 01-11-2018 MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 Pfam PF03466 LysR substrate binding domain 87 290 9.2E-31 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 Gene3D G3DSA:1.10.10.10 1 91 3.2E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 SUPERFAMILY SSF46785 1 87 1.03E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17440 03c4c29eead180d43328f51e0432a47e 291 SUPERFAMILY SSF53850 83 289 8.61E-27 T 01-11-2018 MLA2C4_02885 a39abe1766b6a1d96f0ee639bf65f0b9 106 Pfam PF13024 Protein of unknown function (DUF3884) 20 96 2.3E-27 T 01-11-2018 IPR024979 Protein of unknown function DUF3884 MLA2C4_00130 0bd1fda7263131dcdadb07d500241796 109 Gene3D G3DSA:3.30.1310.10 3 109 5.8E-40 T 01-11-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MLA2C4_00130 0bd1fda7263131dcdadb07d500241796 109 SUPERFAMILY SSF82607 13 106 1.05E-33 T 01-11-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MLA2C4_00130 0bd1fda7263131dcdadb07d500241796 109 PIRSF PIRSF004555 5 109 1.8E-39 T 01-11-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MLA2C4_00130 0bd1fda7263131dcdadb07d500241796 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 23.388 T 01-11-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MLA2C4_00130 0bd1fda7263131dcdadb07d500241796 109 Pfam PF02575 YbaB/EbfC DNA-binding family 13 103 2.6E-34 T 01-11-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MLA2C4_00130 0bd1fda7263131dcdadb07d500241796 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 108 1.6E-32 T 01-11-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MLA2C4_08810 781e5bfdab2b6d12a7580e54dbfce4ea 273 Gene3D G3DSA:2.40.260.10 32 239 4.5E-59 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_08810 781e5bfdab2b6d12a7580e54dbfce4ea 273 Pfam PF04203 Sortase family 99 224 1.3E-25 T 01-11-2018 IPR005754 Sortase family MLA2C4_08810 781e5bfdab2b6d12a7580e54dbfce4ea 273 TIGRFAM TIGR01076 sortase_fam: sortase 97 228 7.4E-44 T 01-11-2018 IPR005754 Sortase family MLA2C4_08810 781e5bfdab2b6d12a7580e54dbfce4ea 273 SUPERFAMILY SSF63817 89 226 3.14E-39 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_17055 2a4043cdf94dba3c5e28225cc893760e 230 Gene3D G3DSA:3.40.50.10420 41 228 2.7E-39 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MLA2C4_17055 2a4043cdf94dba3c5e28225cc893760e 230 SUPERFAMILY SSF100950 42 228 4.6E-41 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_17055 2a4043cdf94dba3c5e28225cc893760e 230 Pfam PF02589 LUD domain 48 228 2.9E-36 T 01-11-2018 IPR003741 LUD domain MLA2C4_03710 e01315929dfa165bb3c0a215149cff86 236 Pfam PF13529 Peptidase_C39 like family 48 207 1.5E-41 T 01-11-2018 IPR039564 Peptidase C39-like MLA2C4_03710 e01315929dfa165bb3c0a215149cff86 236 Gene3D G3DSA:3.90.70.10 41 236 6.2E-80 T 01-11-2018 MLA2C4_03710 e01315929dfa165bb3c0a215149cff86 236 SUPERFAMILY SSF54001 115 205 5.61E-6 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_03710 e01315929dfa165bb3c0a215149cff86 236 PIRSF PIRSF032442 24 236 1.5E-73 T 01-11-2018 IPR016997 Uncharacterised conserved protein UCP032442 MLA2C4_02090 9096fc07430af9737d1289e6f3e739c7 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 4.6E-19 T 01-11-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MLA2C4_02090 9096fc07430af9737d1289e6f3e739c7 76 Pfam PF12728 Helix-turn-helix domain 2 50 2.4E-10 T 01-11-2018 MLA2C4_16020 f00d685fc720b04e85224ef8a3830f09 156 Gene3D G3DSA:3.40.630.30 1 156 9.1E-42 T 01-11-2018 MLA2C4_16020 f00d685fc720b04e85224ef8a3830f09 156 Pfam PF00583 Acetyltransferase (GNAT) family 23 124 5.0E-16 T 01-11-2018 IPR000182 GNAT domain MLA2C4_16020 f00d685fc720b04e85224ef8a3830f09 156 SUPERFAMILY SSF55729 1 154 3.76E-22 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_16020 f00d685fc720b04e85224ef8a3830f09 156 PIRSF PIRSF037663 1 156 1.9E-75 T 01-11-2018 IPR017255 Acetyltransferase, GNAT, predicted MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 PIRSF PIRSF037847 9 180 1.8E-67 T 01-11-2018 IPR026043 Transcription repressor NadR MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 Gene3D G3DSA:3.30.1340.20 75 180 1.4E-37 T 01-11-2018 IPR035922 3H domain superfamily MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 Gene3D G3DSA:1.10.10.10 1 69 2.0E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 Pfam PF08279 HTH domain 14 66 2.4E-15 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 SUPERFAMILY SSF75500 77 179 1.44E-37 T 01-11-2018 IPR035922 3H domain superfamily MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 Pfam PF02829 3H domain 82 178 9.1E-36 T 01-11-2018 IPR004173 3H domain GO:0036094 MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 SUPERFAMILY SSF46785 10 69 3.76E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23110 b55cb1a8778c2286c0363c860f10752e 180 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 85 179 1.0E-50 T 01-11-2018 IPR004173 3H domain GO:0036094 MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 PIRSF PIRSF000094 1 256 3.2E-103 T 01-11-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-12 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-12 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-12 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.4E-12 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.5E-87 T 01-11-2018 MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 Gene3D G3DSA:3.40.50.720 1 256 2.1E-61 T 01-11-2018 MLA2C4_06395 6eb5ebf4c57038968b38ce8fadd6354e 256 SUPERFAMILY SSF51735 5 254 9.74E-68 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_28440 cdfe98e972f19360ff6ca23abfd8f9b2 253 Pfam PF13614 AAA domain 2 178 9.9E-75 T 01-11-2018 IPR025669 AAA domain MLA2C4_28440 cdfe98e972f19360ff6ca23abfd8f9b2 253 SUPERFAMILY SSF52540 1 250 1.96E-71 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28440 cdfe98e972f19360ff6ca23abfd8f9b2 253 PIRSF PIRSF009320 2 85 8.0E-15 T 01-11-2018 MLA2C4_28440 cdfe98e972f19360ff6ca23abfd8f9b2 253 PIRSF PIRSF009320 55 251 7.0E-9 T 01-11-2018 MLA2C4_28440 cdfe98e972f19360ff6ca23abfd8f9b2 253 Gene3D G3DSA:3.40.50.300 1 252 8.7E-84 T 01-11-2018 MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Gene3D G3DSA:3.30.1330.10 392 565 4.9E-62 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 710 6.2E-14 T 01-11-2018 IPR010918 PurM-like, C-terminal domain MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 359 2.4E-34 T 01-11-2018 IPR010918 PurM-like, C-terminal domain MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 3.4E-26 T 01-11-2018 IPR016188 PurM-like, N-terminal domain MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 1.1E-25 T 01-11-2018 IPR016188 PurM-like, N-terminal domain MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 0.0 T 01-11-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 PIRSF PIRSF001587 8 739 0.0 T 01-11-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 SUPERFAMILY SSF55326 18 201 1.94E-53 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 SUPERFAMILY SSF56042 205 430 1.14E-56 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Gene3D G3DSA:3.90.650.10 34 362 2.8E-136 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Gene3D G3DSA:3.30.1330.10 49 197 2.8E-136 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 SUPERFAMILY SSF56042 571 738 2.09E-38 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 SUPERFAMILY SSF55326 401 570 1.83E-57 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Gene3D G3DSA:3.90.650.10 569 739 6.9E-41 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily MLA2C4_01775 5b1128f22bd2c0ab02b20208b49109a5 739 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 739 330.844 T 01-11-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 MLA2C4_00410 78e961e100020d01afb253cbc9a6bd52 120 SMART SM00905 4 117 6.5E-47 T 01-11-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MLA2C4_00410 78e961e100020d01afb253cbc9a6bd52 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 6.4E-42 T 01-11-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MLA2C4_00410 78e961e100020d01afb253cbc9a6bd52 120 TIGRFAM TIGR00526 folB_dom: FolB domain 2 119 1.8E-36 T 01-11-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MLA2C4_00410 78e961e100020d01afb253cbc9a6bd52 120 SUPERFAMILY SSF55620 2 119 1.0E-38 T 01-11-2018 MLA2C4_00410 78e961e100020d01afb253cbc9a6bd52 120 Gene3D G3DSA:3.30.1130.10 1 120 2.1E-45 T 01-11-2018 MLA2C4_00410 78e961e100020d01afb253cbc9a6bd52 120 Pfam PF02152 Dihydroneopterin aldolase 4 116 4.8E-35 T 01-11-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MLA2C4_15980 181106eacf997973a10d369fd7510dd4 290 SMART SM00382 28 207 1.8E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15980 181106eacf997973a10d369fd7510dd4 290 Gene3D G3DSA:3.40.50.300 1 224 2.1E-45 T 01-11-2018 MLA2C4_15980 181106eacf997973a10d369fd7510dd4 290 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_15980 181106eacf997973a10d369fd7510dd4 290 SUPERFAMILY SSF52540 3 220 3.95E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15980 181106eacf997973a10d369fd7510dd4 290 Pfam PF00005 ABC transporter 20 158 3.0E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 Gene3D G3DSA:3.40.50.720 138 263 8.7E-113 T 01-11-2018 MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 SUPERFAMILY SSF51735 116 292 1.02E-32 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 Gene3D G3DSA:3.90.180.10 11 315 8.7E-113 T 01-11-2018 MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 SMART SM00829 13 321 1.7E-8 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 SUPERFAMILY SSF50129 5 147 2.59E-32 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 3.9E-7 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_05375 8d9a6c4a2a7e0199fb20ecbc84c21217 323 Pfam PF00107 Zinc-binding dehydrogenase 154 258 1.1E-14 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_24435 38421204f5767636d4ea7f9542a9b647 284 Gene3D G3DSA:3.60.15.10 4 269 5.7E-87 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_24435 38421204f5767636d4ea7f9542a9b647 284 Pfam PF00753 Metallo-beta-lactamase superfamily 55 232 1.0E-16 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_24435 38421204f5767636d4ea7f9542a9b647 284 SMART SM00849 50 257 3.7E-20 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_24435 38421204f5767636d4ea7f9542a9b647 284 SUPERFAMILY SSF56281 3 263 8.12E-47 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 34 52 - T 01-11-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 Gene3D G3DSA:1.10.10.10 2 90 6.9E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 SMART SM00418 10 89 3.5E-31 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.3E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 2.3E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 2.3E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.3E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 1.5E-18 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16775 2b9778f4f476a2c6a745e18a0c6f8e4b 101 SUPERFAMILY SSF46785 5 85 3.95E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 01-11-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 SMART SM00382 148 411 7.9E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 SUPERFAMILY SSF52540 82 354 6.67E-90 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 Gene3D G3DSA:3.40.50.300 82 350 2.0E-116 T 01-11-2018 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 SUPERFAMILY SSF50615 2 79 7.85E-28 T 01-11-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 Gene3D G3DSA:2.40.10.170 2 80 9.8E-33 T 01-11-2018 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 349 2.6E-68 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 SUPERFAMILY SSF47917 352 467 1.12E-52 T 01-11-2018 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 Gene3D G3DSA:1.10.1140.10 352 469 1.4E-56 T 01-11-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 5.3E-26 T 01-11-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 467 3.8E-259 T 01-11-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MLA2C4_27460 c24b27405b68ec5d3bf94c27e9c50cec 469 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 467 57.948 T 01-11-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 449 735 25.65 T 01-11-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Gene3D G3DSA:3.30.70.3400 35 123 4.4E-23 T 01-11-2018 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 SUPERFAMILY SSF82866 213 415 2.88E-38 T 01-11-2018 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 192 402 1.9E-51 T 01-11-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 559 721 2.9E-48 T 01-11-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Gene3D G3DSA:1.20.1640.10 557 753 6.7E-11 T 01-11-2018 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Pfam PF07549 SecD/SecF GG Motif 471 497 4.9E-7 T 01-11-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Pfam PF07549 SecD/SecF GG Motif 30 51 0.017 T 01-11-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 478 724 2.6E-67 T 01-11-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 PRINTS PR01755 Bacterial translocase SecF protein signature 476 491 3.6E-22 T 01-11-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 PRINTS PR01755 Bacterial translocase SecF protein signature 672 687 3.6E-22 T 01-11-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 PRINTS PR01755 Bacterial translocase SecF protein signature 636 654 3.6E-22 T 01-11-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 PRINTS PR01755 Bacterial translocase SecF protein signature 588 602 3.6E-22 T 01-11-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 SUPERFAMILY SSF82866 557 737 4.71E-37 T 01-11-2018 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Gene3D G3DSA:1.20.1640.10 229 425 2.6E-10 T 01-11-2018 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Pfam PF02355 Protein export membrane protein 555 733 8.3E-63 T 01-11-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Pfam PF02355 Protein export membrane protein 242 410 2.9E-14 T 01-11-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 409 1.6E-99 T 01-11-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MLA2C4_23000 4b8ec1af67c114e03288a49b18615841 754 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 423 32.575 T 01-11-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 161 2.2E-18 T 01-11-2018 IPR016188 PurM-like, N-terminal domain MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 333 5.8E-143 T 01-11-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 Gene3D G3DSA:3.90.650.10 168 346 4.8E-77 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 Gene3D G3DSA:3.30.1330.10 1 167 1.0E-71 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 SUPERFAMILY SSF55326 3 167 9.57E-53 T 01-11-2018 IPR036921 PurM-like, N-terminal domain superfamily MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 48.525 T 01-11-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 338 7.4E-38 T 01-11-2018 IPR010918 PurM-like, C-terminal domain MLA2C4_01785 677cfd5dd2b247701a808066cc3a0d99 346 SUPERFAMILY SSF56042 168 338 5.38E-59 T 01-11-2018 IPR036676 PurM-like, C-terminal domain superfamily MLA2C4_15900 45ad2ae2b028a9dcecf0ad89f66cf239 584 Gene3D G3DSA:3.20.20.140 82 325 2.6E-81 T 01-11-2018 MLA2C4_15900 45ad2ae2b028a9dcecf0ad89f66cf239 584 SUPERFAMILY SSF51338 21 366 1.34E-14 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_15900 45ad2ae2b028a9dcecf0ad89f66cf239 584 Pfam PF13382 Adenine deaminase C-terminal domain 410 571 1.6E-38 T 01-11-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MLA2C4_15900 45ad2ae2b028a9dcecf0ad89f66cf239 584 Gene3D G3DSA:2.30.40.10 21 360 2.6E-81 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_15900 45ad2ae2b028a9dcecf0ad89f66cf239 584 Pfam PF01979 Amidohydrolase family 78 361 1.9E-20 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_15900 45ad2ae2b028a9dcecf0ad89f66cf239 584 SUPERFAMILY SSF51556 83 327 1.09E-10 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 Pfam PF00082 Subtilase family 48 295 1.8E-56 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 Gene3D G3DSA:3.40.50.200 10 315 2.2E-112 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 256 266 - T 01-11-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 94 104 - T 01-11-2018 IPR022398 Peptidase S8, subtilisin, His-active site MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 SUPERFAMILY SSF52743 30 314 2.49E-83 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 53 64 - T 01-11-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 PRINTS PR00723 Subtilisin serine protease family (S8) signature 48 67 4.1E-22 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 PRINTS PR00723 Subtilisin serine protease family (S8) signature 90 103 4.1E-22 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_10180 d2c9c97669905df2336122ea8ade57d3 316 PRINTS PR00723 Subtilisin serine protease family (S8) signature 255 271 4.1E-22 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 353 1.6E-42 T 01-11-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 SUPERFAMILY SSF53756 2 362 1.01E-109 T 01-11-2018 MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 357 1.9E-100 T 01-11-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 3.4E-47 T 01-11-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 Gene3D G3DSA:3.40.50.2000 1 176 1.1E-61 T 01-11-2018 MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 Gene3D G3DSA:3.40.50.2000 177 346 4.5E-50 T 01-11-2018 MLA2C4_20435 24f98ecadec6a2569e86f4e6ee648478 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 34.889 T 01-11-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 16 432 2.3E-133 T 01-11-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 Gene3D G3DSA:2.40.50.140 6 95 2.1E-20 T 01-11-2018 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 199 212 5.4E-22 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 5.4E-22 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 5.4E-22 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 347 363 5.4E-22 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 SUPERFAMILY SSF50249 11 101 1.28E-19 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 Gene3D G3DSA:3.30.930.10 96 432 4.5E-103 T 01-11-2018 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 5 432 40.057 T 01-11-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 SUPERFAMILY SSF55681 89 430 6.33E-85 T 01-11-2018 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 425 1.4E-82 T 01-11-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_11020 fb9a0fa21aa137687bee7d4aa933517e 432 Pfam PF01336 OB-fold nucleic acid binding domain 21 93 1.3E-9 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MLA2C4_17670 9d66ee56369abd7843011de95833343b 255 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 255 3.4E-145 T 01-11-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 MLA2C4_17670 9d66ee56369abd7843011de95833343b 255 Gene3D G3DSA:3.90.550.10 1 255 2.2E-71 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_17670 9d66ee56369abd7843011de95833343b 255 Pfam PF00483 Nucleotidyl transferase 2 227 1.7E-19 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_17670 9d66ee56369abd7843011de95833343b 255 SUPERFAMILY SSF53448 1 255 2.29E-66 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 PIRSF PIRSF002131 1 129 4.2E-54 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 SUPERFAMILY SSF53137 14 129 3.86E-50 T 01-11-2018 MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 Pfam PF00411 Ribosomal protein S11 19 128 1.4E-51 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.0E-59 T 01-11-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 01-11-2018 IPR018102 Ribosomal S11, conserved site MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 Gene3D G3DSA:3.30.420.80 1 129 1.8E-55 T 01-11-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00805 01af3b4a61a994c42ec31f1cbad3bf40 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.407 T 01-11-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 SMART SM00347 32 129 2.5E-15 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 Gene3D G3DSA:1.10.10.10 21 145 3.5E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.5E-7 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 3.5E-7 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.5E-7 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 Pfam PF01047 MarR family 51 93 3.4E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_16800 3d9e96340ede7e16806f5209568d615f 148 SUPERFAMILY SSF46785 36 146 1.58E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 1.9E-22 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 Gene3D G3DSA:3.40.50.2300 1 125 6.5E-41 T 01-11-2018 MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 Pfam PF00072 Response regulator receiver domain 4 113 2.8E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 Gene3D G3DSA:1.10.10.10 126 225 1.8E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 SMART SM00862 143 220 2.4E-21 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 SUPERFAMILY SSF52172 2 170 1.71E-43 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_03440 3745797efaa5515f07e2898b957c6586 225 SMART SM00448 2 112 2.5E-44 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_22355 0905d7863345f4b3523eec83fb938d5f 252 Pfam PF06691 Protein of unknown function (DUF1189) 4 243 7.8E-67 T 01-11-2018 IPR009574 Protein of unknown function DUF1189 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 SMART SM00304 81 133 0.001 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 SMART SM00388 141 208 2.9E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 SMART SM00387 253 364 7.0E-31 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 Gene3D G3DSA:3.30.565.10 208 366 2.9E-35 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 Gene3D G3DSA:1.10.287.130 137 207 8.0E-16 T 01-11-2018 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 6.5E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 6.5E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 6.5E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 Gene3D G3DSA:1.20.1480.50 48 136 6.5E-6 T 01-11-2018 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 206 2.6E-11 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 SUPERFAMILY SSF47384 127 208 3.53E-15 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 SUPERFAMILY SSF55874 197 362 1.07E-38 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 SUPERFAMILY SSF158472 89 132 1.57E-5 T 01-11-2018 MLA2C4_25240 9ea0b41dd6d38fe077e939dba1e7c47a 368 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 363 6.4E-19 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 Pfam PF03418 Germination protease 17 366 4.7E-196 T 01-11-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 Hamap MF_00626 Germination protease [gpr]. 1 367 167.076 T 01-11-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 Gene3D G3DSA:3.40.50.1450 1 367 1.9E-131 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 PIRSF PIRSF019549 3 367 1.6E-191 T 01-11-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 367 0.0 T 01-11-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 SUPERFAMILY SSF53163 3 367 1.18E-132 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily MLA2C4_22565 d2e8ce9fbd123e2d5139d7bdb698896c 367 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 367 3.1E-186 T 01-11-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 SUPERFAMILY SSF51735 3 246 7.23E-95 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 Gene3D G3DSA:3.40.50.720 1 246 3.1E-93 T 01-11-2018 MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.3E-49 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.3E-49 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 6.3E-49 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.3E-49 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.3E-49 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.3E-49 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 3.1E-72 T 01-11-2018 MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 4.0E-5 T 01-11-2018 MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.6E-15 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.6E-15 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.6E-15 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_20125 46968c69df255d405c0d90df5b548f60 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 4.6E-108 T 01-11-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_02955 36f17f48fc02b54041af55a95d92a690 391 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 387 31.464 T 01-11-2018 IPR006698 Uncharacterised protein family UPF0229 MLA2C4_02955 36f17f48fc02b54041af55a95d92a690 391 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 10 382 2.0E-181 T 01-11-2018 IPR014230 Sporulation protein YhbH MLA2C4_02955 36f17f48fc02b54041af55a95d92a690 391 Pfam PF04285 Protein of unknown function (DUF444) 11 186 3.2E-35 T 01-11-2018 IPR006698 Uncharacterised protein family UPF0229 MLA2C4_02955 36f17f48fc02b54041af55a95d92a690 391 Pfam PF04285 Protein of unknown function (DUF444) 192 385 2.3E-68 T 01-11-2018 IPR006698 Uncharacterised protein family UPF0229 MLA2C4_01190 e322e40e1b8de606d2ec3013f79799c7 201 Pfam PF01553 Acyltransferase 18 141 6.5E-26 T 01-11-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MLA2C4_01190 e322e40e1b8de606d2ec3013f79799c7 201 SUPERFAMILY SSF69593 16 193 5.36E-40 T 01-11-2018 MLA2C4_01190 e322e40e1b8de606d2ec3013f79799c7 201 SMART SM00563 33 144 2.7E-28 T 01-11-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 Gene3D G3DSA:3.40.50.300 328 572 3.5E-75 T 01-11-2018 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 Pfam PF00664 ABC transporter transmembrane region 26 280 8.0E-12 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 SUPERFAMILY SSF90123 4 309 5.36E-43 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 Pfam PF00005 ABC transporter 355 500 7.0E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 Gene3D G3DSA:1.20.1560.10 3 314 2.3E-33 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 SMART SM00382 364 547 7.3E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 3 531 3.4E-204 T 01-11-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 MLA2C4_09880 8fe73bd34be61bd08cc2122954efe44a 574 SUPERFAMILY SSF52540 331 570 8.4E-70 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19230 c397039ca0051bccc478fb53e4eaae87 395 Pfam PF14907 Uncharacterised nucleotidyltransferase 41 289 2.7E-66 T 01-11-2018 IPR039498 Uncharacterised nucleotidyltransferase MLA2C4_03610 33c060c4ab90cb0999b74496176fac31 72 SUPERFAMILY SSF47413 3 67 2.06E-16 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_03610 33c060c4ab90cb0999b74496176fac31 72 SMART SM00530 6 61 2.6E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_03610 33c060c4ab90cb0999b74496176fac31 72 Gene3D G3DSA:1.10.260.40 2 67 2.7E-23 T 01-11-2018 MLA2C4_03610 33c060c4ab90cb0999b74496176fac31 72 Pfam PF01381 Helix-turn-helix 7 60 1.8E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_24970 414be6e08bddf9dfd3bed09533700fb1 342 PIRSF PIRSF000267 1 342 1.8E-128 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_24970 414be6e08bddf9dfd3bed09533700fb1 342 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 213 3.8E-53 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_24970 414be6e08bddf9dfd3bed09533700fb1 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 329 8.9E-91 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Gene3D G3DSA:3.30.1480.10 1 124 3.6E-48 T 01-11-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SMART SM00322 229 292 0.031 T 01-11-2018 IPR004087 K Homology domain GO:0003676 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SMART SM00322 300 368 0.25 T 01-11-2018 IPR004087 K Homology domain GO:0003676 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Gene3D G3DSA:3.30.300.20 277 367 1.3E-32 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SUPERFAMILY SSF50249 132 198 1.23E-18 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Pfam PF00575 S1 RNA binding domain 133 195 1.4E-10 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 1.0E-127 T 01-11-2018 IPR010213 Transcription termination factor NusA GO:0003723 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SMART SM00316 133 199 9.3E-10 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SUPERFAMILY SSF54814 278 342 8.5E-17 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Gene3D G3DSA:3.30.300.20 198 276 3.5E-33 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Pfam PF13184 NusA-like KH domain 229 296 2.5E-26 T 01-11-2018 IPR025249 KH domain, NusA-like GO:0003723 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 367 30.5 T 01-11-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SUPERFAMILY SSF54814 199 277 8.5E-30 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 SUPERFAMILY SSF69705 1 126 4.58E-43 T 01-11-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Pfam PF08529 NusA N-terminal domain 4 123 2.6E-43 T 01-11-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MLA2C4_19950 266a196df61f2ce62562d164315146eb 368 Gene3D G3DSA:2.40.50.140 136 197 9.7E-24 T 01-11-2018 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 Pfam PF10415 Fumarase C C-terminus 414 467 1.1E-20 T 01-11-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 ProSitePatterns PS00163 Fumarate lyases signature. 323 332 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 Gene3D G3DSA:1.20.200.10 146 413 5.5E-114 T 01-11-2018 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 Pfam PF00206 Lyase 19 348 1.3E-109 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 Gene3D G3DSA:1.10.275.10 12 145 2.7E-57 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00145 Argininosuccinate lyase family signature 140 162 2.6E-7 T 01-11-2018 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00145 Argininosuccinate lyase family signature 181 201 2.6E-7 T 01-11-2018 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00145 Argininosuccinate lyase family signature 323 339 2.6E-7 T 01-11-2018 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 PRINTS PR00149 Fumarate lyase superfamily signature 323 339 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 Gene3D G3DSA:1.10.40.30 414 465 2.3E-22 T 01-11-2018 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 SUPERFAMILY SSF48557 12 468 8.64E-148 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_09145 ce3a229df1fb77e419ce069d48ed7cbb 479 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 12 473 1.5E-233 T 01-11-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 Gene3D G3DSA:3.40.50.2300 61 302 2.3E-61 T 01-11-2018 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 SMART SM00354 1 71 4.7E-28 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 SUPERFAMILY SSF53822 61 325 1.26E-59 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.3E-5 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.3E-5 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 Gene3D G3DSA:3.40.50.2300 158 285 2.3E-61 T 01-11-2018 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 Pfam PF13377 Periplasmic binding protein-like domain 167 325 5.6E-27 T 01-11-2018 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 SUPERFAMILY SSF47413 1 59 5.98E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 Gene3D G3DSA:1.10.260.40 1 59 8.8E-21 T 01-11-2018 MLA2C4_22035 a178da3dfdac4ededb2d63b4dbe47b96 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 4.0E-19 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 SUPERFAMILY SSF52172 383 547 3.98E-33 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 Pfam PF00072 Response regulator receiver domain 386 496 1.2E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 SMART SM00448 383 496 4.8E-29 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 534 548 1.3E-8 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 564 576 1.3E-8 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 548 564 1.3E-8 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 Gene3D G3DSA:3.30.565.10 248 379 6.7E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 Pfam PF00196 Bacterial regulatory proteins, luxR family 534 588 6.9E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 Pfam PF07730 Histidine kinase 184 245 7.2E-13 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 SUPERFAMILY SSF46894 527 594 6.46E-18 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 Gene3D G3DSA:3.40.50.12740 383 594 3.7E-62 T 01-11-2018 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 SMART SM00421 531 588 1.1E-18 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 SUPERFAMILY SSF55874 252 373 2.88E-16 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_17160 31ee6ae7467f568c0eef9e7e15f89e2f 595 PIRSF PIRSF037435 1 595 0.0 T 01-11-2018 IPR017206 Signal transduction histidine kinase, hybrid-type, BC3207, predicted MLA2C4_05915 3dcd083ffeab7d8d5a29826687ecfeee 302 SUPERFAMILY SSF103481 187 287 5.75E-12 T 01-11-2018 MLA2C4_05915 3dcd083ffeab7d8d5a29826687ecfeee 302 Pfam PF00892 EamA-like transporter family 153 284 4.4E-21 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_05915 3dcd083ffeab7d8d5a29826687ecfeee 302 Pfam PF00892 EamA-like transporter family 9 138 9.2E-16 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_05915 3dcd083ffeab7d8d5a29826687ecfeee 302 SUPERFAMILY SSF103481 40 140 1.7E-12 T 01-11-2018 MLA2C4_12835 346b883abd2d4b92c9490371695c8a21 352 Pfam PF00149 Calcineurin-like phosphoesterase 26 221 8.4E-12 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_12835 346b883abd2d4b92c9490371695c8a21 352 SUPERFAMILY SSF56300 26 276 2.11E-29 T 01-11-2018 MLA2C4_12835 346b883abd2d4b92c9490371695c8a21 352 Gene3D G3DSA:3.60.21.10 24 272 2.5E-25 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 Gene3D G3DSA:1.10.10.60 149 184 8.5E-7 T 01-11-2018 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 SMART SM00857 2 136 3.6E-53 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 SUPERFAMILY SSF53041 1 133 1.57E-42 T 01-11-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 Pfam PF02796 Helix-turn-helix domain of resolvase 139 182 9.2E-7 T 01-11-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 Gene3D G3DSA:3.40.50.1390 1 125 1.6E-44 T 01-11-2018 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 SUPERFAMILY SSF46689 139 182 6.57E-8 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 01-11-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MLA2C4_12970 50f4ddf829f0a807b6d56fe56c1a67f5 187 Pfam PF00239 Resolvase, N terminal domain 3 134 9.0E-41 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 116 3.5E-30 T 01-11-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 SUPERFAMILY SSF56214 1 115 1.57E-34 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 Gene3D G3DSA:3.90.470.20 1 119 9.6E-41 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 109 1.5E-20 T 01-11-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 115 2.0E-54 T 01-11-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 118 6.3E-38 T 01-11-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MLA2C4_01405 454232cdfd1822673437d62558bf101b 119 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 25.328 T 01-11-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MLA2C4_01165 cd5e9f17d6b93d1e2128c84eb75cecf2 33 Pfam PF13134 Protein of unknown function (DUF3948) 1 32 5.8E-18 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 SUPERFAMILY SSF75217 1 242 4.24E-105 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 Gene3D G3DSA:1.10.1270.20 166 244 1.1E-34 T 01-11-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 4.7E-74 T 01-11-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 PIRSF PIRSF000386 1 244 2.9E-107 T 01-11-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 Gene3D G3DSA:3.40.1280.10 1 165 4.7E-71 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 244 115.399 T 01-11-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MLA2C4_20075 063edb2dcdab3192b98638be73be1898 244 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 229 3.2E-104 T 01-11-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MLA2C4_09345 9597cce9c4fd2e098d2ab715eb53a3e7 546 PIRSF PIRSF002741 1 546 4.4E-102 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_09345 9597cce9c4fd2e098d2ab715eb53a3e7 546 SUPERFAMILY SSF53850 39 541 5.25E-124 T 01-11-2018 MLA2C4_09345 9597cce9c4fd2e098d2ab715eb53a3e7 546 Gene3D G3DSA:3.10.105.10 294 517 1.4E-178 T 01-11-2018 MLA2C4_09345 9597cce9c4fd2e098d2ab715eb53a3e7 546 Gene3D G3DSA:3.90.76.10 73 194 1.4E-178 T 01-11-2018 MLA2C4_09345 9597cce9c4fd2e098d2ab715eb53a3e7 546 Gene3D G3DSA:3.40.190.10 54 533 1.4E-178 T 01-11-2018 MLA2C4_09345 9597cce9c4fd2e098d2ab715eb53a3e7 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 464 3.4E-75 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_14095 c03a7b3ce62f9734fd0a5fe0567e560c 182 Pfam PF07155 ECF-type riboflavin transporter, S component 3 170 2.5E-35 T 01-11-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 MLA2C4_14095 c03a7b3ce62f9734fd0a5fe0567e560c 182 Gene3D G3DSA:1.10.1760.20 1 174 4.9E-17 T 01-11-2018 MLA2C4_14095 c03a7b3ce62f9734fd0a5fe0567e560c 182 Hamap MF_01572 UPF0397 protein . 2 181 21.242 T 01-11-2018 IPR022914 Protein of unknown function UPF0397 MLA2C4_01050 91043379943fbff1c708fb49538a6efe 572 Pfam PF13139 Domain of unknown function (DUF3981) 13 126 1.1E-73 T 01-11-2018 IPR025043 Domain of unknown function DUF3981 MLA2C4_27015 bfacf839afb19d6c69f1d0e010e3d620 451 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 437 1.8E-116 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MLA2C4_27015 bfacf839afb19d6c69f1d0e010e3d620 451 PIRSF PIRSF006446 1 451 3.5E-107 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MLA2C4_02670 45ab0b3070fefeb95092642f8c83e3bb 376 Pfam PF01979 Amidohydrolase family 52 368 2.1E-18 T 01-11-2018 IPR006680 Amidohydrolase-related GO:0016787 MLA2C4_02670 45ab0b3070fefeb95092642f8c83e3bb 376 Gene3D G3DSA:2.30.40.10 6 366 2.5E-104 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_02670 45ab0b3070fefeb95092642f8c83e3bb 376 SUPERFAMILY SSF51556 54 336 1.23E-42 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_02670 45ab0b3070fefeb95092642f8c83e3bb 376 SUPERFAMILY SSF51338 3 371 3.43E-21 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_02670 45ab0b3070fefeb95092642f8c83e3bb 376 Gene3D G3DSA:3.20.20.140 55 332 2.5E-104 T 01-11-2018 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 Pfam PF01739 CheR methyltransferase, SAM binding domain 70 245 3.6E-55 T 01-11-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 SUPERFAMILY SSF53335 70 243 6.72E-44 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 Gene3D G3DSA:3.40.50.150 69 260 1.0E-59 T 01-11-2018 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 56 6.7E-8 T 01-11-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 SUPERFAMILY SSF47757 4 69 2.62E-9 T 01-11-2018 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 SMART SM00138 4 258 3.9E-76 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 PRINTS PR00996 Glutamate methyltransferase family signature 218 241 2.6E-36 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 PRINTS PR00996 Glutamate methyltransferase family signature 26 39 2.6E-36 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 PRINTS PR00996 Glutamate methyltransferase family signature 63 75 2.6E-36 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 PRINTS PR00996 Glutamate methyltransferase family signature 199 213 2.6E-36 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 PRINTS PR00996 Glutamate methyltransferase family signature 133 149 2.6E-36 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_08550 17a7696ed205ba20f62873845b487c4e 260 PRINTS PR00996 Glutamate methyltransferase family signature 101 121 2.6E-36 T 01-11-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MLA2C4_05845 f353088dc5f6f20d3952e4cc3de1db68 110 Pfam PF01638 HxlR-like helix-turn-helix 20 106 5.4E-34 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_05845 f353088dc5f6f20d3952e4cc3de1db68 110 Gene3D G3DSA:1.10.10.10 10 110 3.4E-43 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05845 f353088dc5f6f20d3952e4cc3de1db68 110 SUPERFAMILY SSF46785 11 105 4.69E-36 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_09090 d706470b92433fdb696b61839ee27c3b 312 SUPERFAMILY SSF52540 3 222 1.03E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09090 d706470b92433fdb696b61839ee27c3b 312 Pfam PF13732 Domain of unknown function (DUF4162) 216 304 9.9E-7 T 01-11-2018 IPR025302 Domain of unknown function DUF4162 MLA2C4_09090 d706470b92433fdb696b61839ee27c3b 312 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_09090 d706470b92433fdb696b61839ee27c3b 312 SMART SM00382 28 210 1.3E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09090 d706470b92433fdb696b61839ee27c3b 312 Pfam PF00005 ABC transporter 19 162 3.0E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09090 d706470b92433fdb696b61839ee27c3b 312 Gene3D G3DSA:3.40.50.300 1 240 9.4E-72 T 01-11-2018 MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 Pfam PF00557 Metallopeptidase family M24 136 338 5.1E-70 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 Gene3D G3DSA:3.90.230.10 127 354 1.3E-86 T 01-11-2018 MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 128 2.9E-25 T 01-11-2018 IPR000587 Creatinase, N-terminal GO:0016787 MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 224 7.6E-7 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 306 318 7.6E-7 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 Gene3D G3DSA:3.40.350.10 2 126 2.4E-35 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 SUPERFAMILY SSF53092 1 126 9.68E-28 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 284 296 - T 01-11-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MLA2C4_20265 dbf1adcad54010c91a451ee4a4bcd72b 356 SUPERFAMILY SSF55920 85 348 9.29E-84 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_06660 134745756d55560f7131e32d28978ea4 579 Pfam PF01926 50S ribosome-binding GTPase 53 185 1.1E-11 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_06660 134745756d55560f7131e32d28978ea4 579 SUPERFAMILY SSF52540 30 216 1.51E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06660 134745756d55560f7131e32d28978ea4 579 Gene3D G3DSA:3.40.50.300 3 268 4.9E-24 T 01-11-2018 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 208 59.759 T 01-11-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 Pfam PF01634 ATP phosphoribosyltransferase 53 204 1.3E-51 T 01-11-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 SUPERFAMILY SSF53850 3 206 8.07E-67 T 01-11-2018 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 184 7.4E-64 T 01-11-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 Gene3D G3DSA:3.40.190.10 94 176 1.6E-76 T 01-11-2018 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 Gene3D G3DSA:3.40.190.10 6 196 1.6E-76 T 01-11-2018 MLA2C4_07430 4421e8bd82b05986904c95252918360f 211 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 01-11-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 342 47.14 T 01-11-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 01-11-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 01-11-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 340 2.0E-125 T 01-11-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 6.2E-124 T 01-11-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 Gene3D G3DSA:3.20.20.210 2 347 5.6E-143 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MLA2C4_05705 1cdebe4192383fb345fe03ea375efac3 348 SUPERFAMILY SSF51726 4 343 1.83E-104 T 01-11-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 SUPERFAMILY SSF52009 465 583 6.93E-31 T 01-11-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Gene3D G3DSA:3.50.30.10 474 585 1.9E-34 T 01-11-2018 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Gene3D G3DSA:3.20.20.60 2 333 9.1E-196 T 01-11-2018 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 5.6E-156 T 01-11-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Gene3D G3DSA:3.40.1380.20 334 468 9.1E-196 T 01-11-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 9.4E-190 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Gene3D G3DSA:2.40.33.10 70 166 9.1E-196 T 01-11-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 01-11-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 SUPERFAMILY SSF50800 70 165 7.33E-27 T 01-11-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 267 291 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 215 241 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 242 266 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 59 75 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 311 327 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 184 198 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 PRINTS PR01050 Pyruvate kinase family signature 292 310 8.3E-80 T 01-11-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 SUPERFAMILY SSF51621 1 340 8.72E-104 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 470 8.2E-36 T 01-11-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 504 575 2.2E-21 T 01-11-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MLA2C4_23890 98bec07b3c0efd3d0bb9ad1dfbcddc12 585 SUPERFAMILY SSF52935 321 473 3.4E-42 T 01-11-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MLA2C4_10610 3e906c95b00920fe1c5cae1bbdcc06c4 208 Pfam PF07853 Protein of unknown function (DUF1648) 9 53 1.3E-8 T 01-11-2018 IPR012867 Domain of unknown function DUF1648 MLA2C4_10610 3e906c95b00920fe1c5cae1bbdcc06c4 208 PIRSF PIRSF038959 1 203 9.3E-62 T 01-11-2018 IPR026272 Immunity protein SdpI MLA2C4_25195 25f925ef8d7c483544c6095289cb63b3 63 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 19 38 6.3E-10 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_25195 25f925ef8d7c483544c6095289cb63b3 63 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 19 40 1.1E-9 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_22790 1f8aea056916f72f692a55d18098c378 315 SUPERFAMILY SSF53807 42 309 9.03E-58 T 01-11-2018 MLA2C4_22790 1f8aea056916f72f692a55d18098c378 315 Gene3D G3DSA:3.40.50.1980 141 312 1.2E-49 T 01-11-2018 MLA2C4_22790 1f8aea056916f72f692a55d18098c378 315 Pfam PF01497 Periplasmic binding protein 76 289 1.6E-34 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_22790 1f8aea056916f72f692a55d18098c378 315 Gene3D G3DSA:3.40.50.1980 35 132 1.6E-15 T 01-11-2018 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 Gene3D G3DSA:3.30.70.920 53 137 8.9E-16 T 01-11-2018 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.7E-10 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.7E-10 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.7E-10 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 6.4E-16 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 SUPERFAMILY SSF54909 66 133 1.06E-12 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 Pfam PF01037 Lrp/AsnC ligand binding domain 81 130 4.6E-9 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 Gene3D G3DSA:1.10.10.10 1 52 8.6E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 SMART SM00344 1 105 2.6E-25 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_11350 9da0d57bcfaf4b23cad1651cb0c233c7 145 SUPERFAMILY SSF46785 1 59 6.75E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12140 7dbb58c1c2a5588880f51c1cad9fb47b 210 PIRSF PIRSF006324 1 209 4.5E-62 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_12140 7dbb58c1c2a5588880f51c1cad9fb47b 210 Pfam PF01810 LysE type translocator 14 206 6.5E-38 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 Gene3D G3DSA:3.40.50.720 2 147 1.9E-59 T 01-11-2018 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 01-11-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 Gene3D G3DSA:3.90.110.10 148 313 9.7E-63 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 1.2E-49 T 01-11-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 SUPERFAMILY SSF51735 4 145 1.56E-56 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 47.88 T 01-11-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 6.0E-49 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 6.0E-49 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 6.0E-49 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 6.0E-49 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 6.0E-49 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 SUPERFAMILY SSF56327 146 312 9.66E-58 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 2.1E-37 T 01-11-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 PIRSF PIRSF000102 2 313 1.1E-114 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_09770 0952bd071901ff799328c78d4f930de1 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 6.3E-134 T 01-11-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 Gene3D G3DSA:1.10.357.10 53 191 1.5E-18 T 01-11-2018 MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 SUPERFAMILY SSF46689 2 67 8.25E-16 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 51 4.1E-13 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 Gene3D G3DSA:1.10.10.60 1 52 7.4E-16 T 01-11-2018 MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 SUPERFAMILY SSF48498 80 192 8.45E-5 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.2E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_22040 be9f2a8d0dc694f1788562e6f5a91807 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.2E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23490 5ff55492d2a7ae7643a61bdaded4a901 208 SUPERFAMILY SSF81343 4 203 7.85E-63 T 01-11-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23490 5ff55492d2a7ae7643a61bdaded4a901 208 PIRSF PIRSF000170 1 204 6.8E-105 T 01-11-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute MLA2C4_23490 5ff55492d2a7ae7643a61bdaded4a901 208 Gene3D G3DSA:1.20.1300.10 1 208 9.0E-48 T 01-11-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23490 5ff55492d2a7ae7643a61bdaded4a901 208 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 190 1.3E-12 T 01-11-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MLA2C4_23490 5ff55492d2a7ae7643a61bdaded4a901 208 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 5 200 1.7E-55 T 01-11-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 Pfam PF13091 PLD-like domain 167 309 3.2E-11 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 Pfam PF13091 PLD-like domain 356 481 9.4E-29 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 Pfam PF13396 Phospholipase_D-nuclease N-terminal 57 93 1.6E-8 T 01-11-2018 IPR027379 Cardiolipin synthase N-terminal MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 Gene3D G3DSA:3.30.870.10 343 486 3.0E-30 T 01-11-2018 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 SUPERFAMILY SSF56024 301 500 6.06E-51 T 01-11-2018 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 43 514 1.4E-186 T 01-11-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 SMART SM00155 427 454 8.1E-7 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 SMART SM00155 249 276 5.7E-5 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 Gene3D G3DSA:3.30.870.10 145 332 8.6E-47 T 01-11-2018 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 SUPERFAMILY SSF56024 143 344 4.91E-50 T 01-11-2018 MLA2C4_06270 561da5ef694e39ebdd382c20899c170a 514 Hamap MF_01916 Cardiolipin synthase. 45 514 43.907 T 01-11-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 SMART SM00904 185 311 5.9E-62 T 01-11-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 Pfam PF06574 FAD synthetase 18 169 1.1E-46 T 01-11-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 SUPERFAMILY SSF82114 176 314 2.62E-47 T 01-11-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 PIRSF PIRSF004491 2 317 7.4E-105 T 01-11-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 57 3.8E-7 T 01-11-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 SUPERFAMILY SSF52374 19 178 2.82E-28 T 01-11-2018 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 310 9.6E-95 T 01-11-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 Gene3D G3DSA:2.40.30.30 188 323 1.2E-44 T 01-11-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 Gene3D G3DSA:3.40.50.620 5 187 5.1E-52 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_19915 07dfee8e929c2fbe3da871e8be2a9cd6 323 Pfam PF01687 Riboflavin kinase 186 310 3.7E-38 T 01-11-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MLA2C4_12705 6d6240109d1cd7eae8aa79703a1b1884 210 Pfam PF00190 Cupin 32 154 1.3E-10 T 01-11-2018 IPR006045 Cupin 1 GO:0045735 MLA2C4_12705 6d6240109d1cd7eae8aa79703a1b1884 210 SMART SM00835 21 158 1.2E-15 T 01-11-2018 IPR006045 Cupin 1 GO:0045735 MLA2C4_12705 6d6240109d1cd7eae8aa79703a1b1884 210 SUPERFAMILY SSF51182 30 172 2.05E-27 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_12705 6d6240109d1cd7eae8aa79703a1b1884 210 Gene3D G3DSA:2.60.120.10 2 173 7.1E-26 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_27715 3f2a92ea9a6a9fb8dcbc1e268a636308 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 282 330 9.8E-7 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_27715 3f2a92ea9a6a9fb8dcbc1e268a636308 376 Gene3D G3DSA:3.30.565.10 242 365 2.6E-29 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_27715 3f2a92ea9a6a9fb8dcbc1e268a636308 376 Pfam PF07730 Histidine kinase 178 241 1.0E-19 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_27715 3f2a92ea9a6a9fb8dcbc1e268a636308 376 SUPERFAMILY SSF55874 251 365 6.16E-12 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Pfam PF00702 haloacid dehalogenase-like hydrolase 369 655 1.1E-19 T 01-11-2018 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Gene3D G3DSA:1.20.1110.10 679 796 6.3E-78 T 01-11-2018 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 SUPERFAMILY SSF81660 341 545 5.01E-42 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 17 900 0.0 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Pfam PF00690 Cation transporter/ATPase, N-terminus 30 95 2.1E-17 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 375 381 - T 01-11-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Gene3D G3DSA:2.70.150.10 43 278 2.6E-81 T 01-11-2018 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Pfam PF00122 E1-E2 ATPase 154 353 7.6E-46 T 01-11-2018 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 274 391 1.0E-19 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 608 730 1.3E-28 T 01-11-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 SUPERFAMILY SSF81665 29 898 5.75E-103 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 717 728 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 699 714 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 303 322 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 854 875 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 286 302 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 804 825 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 407 420 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 749 762 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 PRINTS PR01836 Magnesium-transporting ATPase signature 769 785 3.6E-82 T 01-11-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 SUPERFAMILY SSF81653 154 273 7.06E-28 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Gene3D G3DSA:3.40.50.1000 549 678 6.3E-78 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Gene3D G3DSA:3.40.50.1000 371 382 2.6E-81 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 SUPERFAMILY SSF56784 533 683 1.6E-35 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Gene3D G3DSA:1.20.1110.10 69 370 2.6E-81 T 01-11-2018 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 SMART SM00831 27 100 1.1E-21 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_21670 8c586aab6d769f4c336626bbf8c16ba1 901 Gene3D G3DSA:3.40.1110.10 425 548 6.3E-78 T 01-11-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 SUPERFAMILY SSF56801 4 501 1.15E-125 T 01-11-2018 MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 Hamap MF_00593 D-alanine--D-alanyl carrier protein ligase [dltA]. 1 504 244.827 T 01-11-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 Gene3D G3DSA:3.40.50.12780 1 397 1.8E-153 T 01-11-2018 MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 Gene3D G3DSA:3.30.300.30 398 504 3.4E-32 T 01-11-2018 MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 492 1.6E-8 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 503 4.0E-214 T 01-11-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 428 7.0E-106 T 01-11-2018 IPR010071 Amino acid adenylation domain MLA2C4_07275 f435f9956a88dce1a9735e5e514eb1c4 504 Pfam PF00501 AMP-binding enzyme 8 404 2.0E-84 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 SUPERFAMILY SSF53067 3 252 4.4E-54 T 01-11-2018 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 Gene3D G3DSA:3.30.420.40 1 244 2.0E-59 T 01-11-2018 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 SUPERFAMILY SSF53067 251 501 3.99E-50 T 01-11-2018 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 249 2.1E-49 T 01-11-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 Gene3D G3DSA:3.30.420.40 245 509 3.4E-55 T 01-11-2018 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 PIRSF PIRSF000538 1 508 1.1E-123 T 01-11-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_15680 5c9e64d8e3f97bdac147a538919b672a 520 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 289 456 4.9E-18 T 01-11-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.5E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.5E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 SMART SM00866 90 227 1.2E-31 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 SMART SM00345 8 67 5.8E-14 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 Gene3D G3DSA:1.10.10.10 1 67 2.7E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 Gene3D G3DSA:3.40.1410.10 74 228 3.9E-39 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 SUPERFAMILY SSF64288 77 229 6.44E-40 T 01-11-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 SUPERFAMILY SSF46785 4 71 1.95E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 Pfam PF07702 UTRA domain 92 226 1.1E-32 T 01-11-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MLA2C4_19640 e17279e5b4498bbcb272f187b5c8283c 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.4E-16 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 Gene3D G3DSA:1.10.287.40 1 105 8.2E-27 T 01-11-2018 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 SUPERFAMILY SSF46589 1 113 7.85E-32 T 01-11-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 PIRSF PIRSF001529 1 424 1.2E-192 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 9.8E-34 T 01-11-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 3.9E-183 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 Gene3D G3DSA:3.30.930.10 106 424 3.7E-131 T 01-11-2018 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 6.1E-32 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 6.1E-32 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 6.1E-32 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 6.1E-32 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 6.1E-32 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 SUPERFAMILY SSF55681 117 423 4.33E-107 T 01-11-2018 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 1.1E-39 T 01-11-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_00085 8eae9250581d7e6727fcca6b6e43a78d 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.375 T 01-11-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MLA2C4_22190 aef73b33ed0b511124b627465a0f7af1 347 SUPERFAMILY SSF52540 4 286 7.22E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22190 aef73b33ed0b511124b627465a0f7af1 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 01-11-2018 IPR001482 Type II/IV secretion system protein MLA2C4_22190 aef73b33ed0b511124b627465a0f7af1 347 Gene3D G3DSA:3.30.450.90 2 108 2.2E-28 T 01-11-2018 MLA2C4_22190 aef73b33ed0b511124b627465a0f7af1 347 SMART SM00382 136 260 1.3E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_22190 aef73b33ed0b511124b627465a0f7af1 347 Gene3D G3DSA:3.40.50.300 111 337 2.0E-67 T 01-11-2018 MLA2C4_22190 aef73b33ed0b511124b627465a0f7af1 347 Pfam PF00437 Type II/IV secretion system protein 13 275 1.3E-71 T 01-11-2018 IPR001482 Type II/IV secretion system protein MLA2C4_25805 a426e0dd2971205148f2510334270868 254 Pfam PF13242 HAD-hyrolase-like 177 249 1.1E-21 T 01-11-2018 MLA2C4_25805 a426e0dd2971205148f2510334270868 254 Gene3D G3DSA:3.40.50.1000 4 240 5.5E-89 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_25805 a426e0dd2971205148f2510334270868 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 226 4.1E-42 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MLA2C4_25805 a426e0dd2971205148f2510334270868 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 2 250 6.5E-125 T 01-11-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 MLA2C4_25805 a426e0dd2971205148f2510334270868 254 Gene3D G3DSA:3.40.50.1000 82 177 5.5E-89 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_25805 a426e0dd2971205148f2510334270868 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 2.6E-27 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MLA2C4_25805 a426e0dd2971205148f2510334270868 254 PIRSF PIRSF000915 1 113 2.5E-26 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MLA2C4_25805 a426e0dd2971205148f2510334270868 254 PIRSF PIRSF000915 108 253 1.6E-34 T 01-11-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA MLA2C4_25805 a426e0dd2971205148f2510334270868 254 SUPERFAMILY SSF56784 1 251 1.68E-76 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_12510 e19769475b841540f0efc2e6b9902918 228 Pfam PF03473 MOSC domain 53 162 1.5E-24 T 01-11-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MLA2C4_12510 e19769475b841540f0efc2e6b9902918 228 Pfam PF03475 3-alpha domain 173 214 2.2E-13 T 01-11-2018 IPR005163 3-alpha domain MLA2C4_12510 e19769475b841540f0efc2e6b9902918 228 SUPERFAMILY SSF50800 4 218 6.28E-73 T 01-11-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MLA2C4_12510 e19769475b841540f0efc2e6b9902918 228 Gene3D G3DSA:2.40.33.20 1 228 6.0E-76 T 01-11-2018 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 2.2E-38 T 01-11-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 SUPERFAMILY SSF51735 4 145 2.14E-57 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 48.458 T 01-11-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 01-11-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 Gene3D G3DSA:3.40.50.720 2 147 1.2E-59 T 01-11-2018 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 PIRSF PIRSF000102 2 313 3.9E-117 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 3.8E-49 T 01-11-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 Gene3D G3DSA:3.90.110.10 148 313 8.0E-65 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 9.3E-50 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 9.3E-50 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 9.3E-50 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 9.3E-50 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 9.3E-50 T 01-11-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 SUPERFAMILY SSF56327 146 312 5.91E-59 T 01-11-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MLA2C4_25340 5d3f2c8658befd43f2b3171fc3fd9050 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 4.6E-136 T 01-11-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 Gene3D G3DSA:3.10.560.10 49 145 5.0E-10 T 01-11-2018 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 Pfam PF10531 SLBB domain 64 113 1.3E-11 T 01-11-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 SMART SM00278 146 165 0.097 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 SMART SM00278 176 195 8.1 T 01-11-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 Pfam PF12836 Helix-hairpin-helix motif 135 196 8.9E-22 T 01-11-2018 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 136 198 1.5E-24 T 01-11-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 Gene3D G3DSA:1.10.150.310 146 199 4.8E-14 T 01-11-2018 MLA2C4_22595 5a6d7c224982103103e561fc6b7f7b04 199 SUPERFAMILY SSF47781 126 198 6.34E-27 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_11470 117301d76aa716da1e97e7bc1104d8b4 232 Gene3D G3DSA:3.40.1080.10 9 224 1.4E-76 T 01-11-2018 MLA2C4_11470 117301d76aa716da1e97e7bc1104d8b4 232 Pfam PF01144 Coenzyme A transferase 13 220 4.6E-65 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MLA2C4_11470 117301d76aa716da1e97e7bc1104d8b4 232 SUPERFAMILY SSF100950 10 224 2.63E-74 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_11470 117301d76aa716da1e97e7bc1104d8b4 232 SMART SM00882 11 222 9.3E-68 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MLA2C4_11470 117301d76aa716da1e97e7bc1104d8b4 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 12 222 3.1E-61 T 01-11-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 SUPERFAMILY SSF55874 294 459 4.58E-47 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 Gene3D G3DSA:1.10.287.130 234 304 5.2E-24 T 01-11-2018 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 Gene3D G3DSA:3.30.565.10 309 464 2.7E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 458 9.9E-27 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 Gene3D G3DSA:1.10.8.500 186 233 1.2E-10 T 01-11-2018 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 SUPERFAMILY SSF47384 221 304 1.67E-20 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 SMART SM00304 185 237 8.3E-13 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 303 3.0E-20 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 SMART SM00388 238 304 3.7E-21 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 SUPERFAMILY SSF158472 186 233 9.02E-12 T 01-11-2018 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 Pfam PF00672 HAMP domain 187 233 6.7E-14 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 4.1E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 4.1E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 4.1E-13 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_06915 39d686049e6cd36a083cadbffb411cac 466 SMART SM00387 349 461 9.1E-37 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_12375 2c8d55a2dec81331f4a1c4c54ce8628a 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_12375 2c8d55a2dec81331f4a1c4c54ce8628a 146 Gene3D G3DSA:1.10.10.10 1 142 1.2E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_12375 2c8d55a2dec81331f4a1c4c54ce8628a 146 Pfam PF13463 Winged helix DNA-binding domain 41 97 1.8E-7 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_12375 2c8d55a2dec81331f4a1c4c54ce8628a 146 SUPERFAMILY SSF46785 27 144 1.37E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12375 2c8d55a2dec81331f4a1c4c54ce8628a 146 SMART SM00347 24 125 1.3E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 SUPERFAMILY SSF51735 4 155 4.64E-36 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 128 3.4E-32 T 01-11-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 Gene3D G3DSA:3.40.50.720 5 263 7.5E-74 T 01-11-2018 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 3.9E-85 T 01-11-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 Gene3D G3DSA:3.30.360.10 130 235 7.5E-74 T 01-11-2018 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 PIRSF PIRSF000161 2 266 4.9E-68 T 01-11-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 SUPERFAMILY SSF55347 129 237 4.14E-38 T 01-11-2018 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 01-11-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 264 4.5E-32 T 01-11-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_08060 3bec75ef856b6f2cb2d0d4dc4e2c7f0e 266 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 266 29.743 T 01-11-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_04370 524f3ea4f48ccf1723eeb657bbcb736c 361 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 358 8.8E-142 T 01-11-2018 IPR008589 Protein of unknown function DUF871, prokaryotic MLA2C4_04370 524f3ea4f48ccf1723eeb657bbcb736c 361 SUPERFAMILY SSF51445 2 243 6.7E-93 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_04370 524f3ea4f48ccf1723eeb657bbcb736c 361 Gene3D G3DSA:3.20.20.70 1 242 3.6E-98 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_04370 524f3ea4f48ccf1723eeb657bbcb736c 361 Gene3D G3DSA:2.40.100.10 243 361 1.1E-44 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_04370 524f3ea4f48ccf1723eeb657bbcb736c 361 SUPERFAMILY SSF50891 246 360 1.93E-36 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 SUPERFAMILY SSF49478 626 694 1.02E-7 T 01-11-2018 MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 45 327 1.3E-20 T 01-11-2018 IPR026588 Choice-of-anchor A domain MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 713 743 2.4E-4 T 01-11-2018 MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 SUPERFAMILY SSF49478 532 600 2.35E-8 T 01-11-2018 MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 Gene3D G3DSA:2.60.40.10 526 618 4.6E-22 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 Gene3D G3DSA:2.60.40.10 620 719 9.7E-23 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 SUPERFAMILY SSF49478 343 412 1.14E-7 T 01-11-2018 MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 SUPERFAMILY SSF49478 438 505 3.22E-8 T 01-11-2018 MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 Gene3D G3DSA:2.60.40.10 431 524 8.4E-22 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13585 f497b8e924f29f21ab55f461f28c6a52 746 Gene3D G3DSA:2.60.40.10 337 430 1.5E-23 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_23530 2ff911d9f71f1496f935203452163518 561 Gene3D G3DSA:3.40.50.12780 12 447 2.3E-135 T 01-11-2018 MLA2C4_23530 2ff911d9f71f1496f935203452163518 561 Pfam PF00501 AMP-binding enzyme 29 456 1.8E-119 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_23530 2ff911d9f71f1496f935203452163518 561 SUPERFAMILY SSF56801 16 551 6.41E-163 T 01-11-2018 MLA2C4_23530 2ff911d9f71f1496f935203452163518 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 209 220 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_23530 2ff911d9f71f1496f935203452163518 561 Gene3D G3DSA:3.30.300.310 453 557 2.7E-32 T 01-11-2018 MLA2C4_23530 2ff911d9f71f1496f935203452163518 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 541 1.6E-20 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_10420 5b541ef4882dd89b3ca0629b106c8240 206 Gene3D G3DSA:3.40.50.720 1 206 7.7E-39 T 01-11-2018 MLA2C4_10420 5b541ef4882dd89b3ca0629b106c8240 206 SUPERFAMILY SSF51735 1 204 3.26E-29 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_10420 5b541ef4882dd89b3ca0629b106c8240 206 Pfam PF13460 NAD(P)H-binding 7 191 3.6E-36 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_27420 39957167f6e36376c09fcb76f545fa23 366 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 3 366 47.008 T 01-11-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27420 39957167f6e36376c09fcb76f545fa23 366 Gene3D G3DSA:1.10.645.20 4 366 9.2E-152 T 01-11-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27420 39957167f6e36376c09fcb76f545fa23 366 SUPERFAMILY SSF56762 16 365 1.44E-118 T 01-11-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27420 39957167f6e36376c09fcb76f545fa23 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 291 365 2.9E-25 T 01-11-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27420 39957167f6e36376c09fcb76f545fa23 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 291 1.5E-68 T 01-11-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 Pfam PF00293 NUDIX domain 28 96 9.2E-14 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 Gene3D G3DSA:3.90.79.10 1 157 1.2E-46 T 01-11-2018 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.4E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.4E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 SUPERFAMILY SSF55811 27 110 5.15E-22 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_24910 8bf4b4c4a58fe6f6461dccf56b8c3e33 159 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 157 4.4E-75 T 01-11-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 ProSitePatterns PS00942 glpT family of transporters signature. 155 171 - T 01-11-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 37 421 1.6E-154 T 01-11-2018 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 SUPERFAMILY SSF103473 13 440 1.96E-79 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 PIRSF PIRSF002808 7 449 5.3E-164 T 01-11-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 5 442 1.5E-226 T 01-11-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 Pfam PF07690 Major Facilitator Superfamily 36 402 6.9E-50 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 Gene3D G3DSA:1.20.1250.20 244 448 8.8E-55 T 01-11-2018 MLA2C4_03490 32fa8ae855346649b4123e83b2d512ab 449 Gene3D G3DSA:1.20.1250.20 20 229 1.4E-56 T 01-11-2018 MLA2C4_23790 5136d019c849920ab16bfc97dc5ac2ee 468 Pfam PF07261 Replication initiation and membrane attachment 326 391 2.3E-9 T 01-11-2018 IPR006343 DnaD domain MLA2C4_03205 7019d52c0403914e058317fa5d6c0828 128 Gene3D G3DSA:3.10.180.10 8 127 4.1E-32 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_03205 7019d52c0403914e058317fa5d6c0828 128 SUPERFAMILY SSF54593 1 127 2.42E-31 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_03205 7019d52c0403914e058317fa5d6c0828 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 125 1.0E-18 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_04635 79c08f49751967e17bf13c9c11122cab 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 01-11-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MLA2C4_04635 79c08f49751967e17bf13c9c11122cab 479 Pfam PF00171 Aldehyde dehydrogenase family 15 472 6.9E-157 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_04635 79c08f49751967e17bf13c9c11122cab 479 Gene3D G3DSA:3.40.605.10 23 255 8.1E-159 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_04635 79c08f49751967e17bf13c9c11122cab 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 01-11-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MLA2C4_04635 79c08f49751967e17bf13c9c11122cab 479 SUPERFAMILY SSF53720 5 477 2.88E-151 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_04635 79c08f49751967e17bf13c9c11122cab 479 Gene3D G3DSA:3.40.309.10 258 437 8.1E-159 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 SUPERFAMILY SSF88659 102 158 3.36E-12 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 Pfam PF04542 Sigma-70 region 2 28 74 8.9E-7 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 SUPERFAMILY SSF88946 15 84 3.53E-10 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 Pfam PF08281 Sigma-70, region 4 115 154 1.4E-12 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 Gene3D G3DSA:1.10.1740.10 4 78 3.0E-12 T 01-11-2018 MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 158 1.8E-18 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_01000 9473c0fe6be7bf2200000c48bb90618d 163 Gene3D G3DSA:1.10.10.10 100 159 2.3E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03945 add8ebc397ce54161f69acbc9354917d 369 SUPERFAMILY SSF54373 226 310 1.96E-18 T 01-11-2018 MLA2C4_03945 add8ebc397ce54161f69acbc9354917d 369 Gene3D G3DSA:3.30.9.10 92 311 1.2E-109 T 01-11-2018 MLA2C4_03945 add8ebc397ce54161f69acbc9354917d 369 Gene3D G3DSA:3.50.50.60 6 352 1.2E-109 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_03945 add8ebc397ce54161f69acbc9354917d 369 SUPERFAMILY SSF51905 4 361 1.49E-52 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_03945 add8ebc397ce54161f69acbc9354917d 369 Pfam PF01266 FAD dependent oxidoreductase 6 351 4.4E-74 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_03945 add8ebc397ce54161f69acbc9354917d 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 356 5.8E-129 T 01-11-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 MLA2C4_16240 316a51a06c0f8932d9ecf16c0c531785 354 Pfam PF01757 Acyltransferase family 6 346 3.5E-28 T 01-11-2018 IPR002656 Acyltransferase 3 GO:0016747 MLA2C4_26545 05bb7761fd20c194a9c85684f58ea8b8 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 2.0E-25 T 01-11-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MLA2C4_26545 05bb7761fd20c194a9c85684f58ea8b8 77 Pfam PF03840 Preprotein translocase SecG subunit 4 75 3.9E-24 T 01-11-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MLA2C4_26545 05bb7761fd20c194a9c85684f58ea8b8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 1.0E-11 T 01-11-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MLA2C4_26545 05bb7761fd20c194a9c85684f58ea8b8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.0E-11 T 01-11-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MLA2C4_26545 05bb7761fd20c194a9c85684f58ea8b8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.0E-11 T 01-11-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MLA2C4_03540 3e8c21e1722629fa836c1c7612640f11 801 Pfam PF05547 Immune inhibitor A peptidase M6 155 797 0.0 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_03540 3e8c21e1722629fa836c1c7612640f11 801 PIRSF PIRSF007519 1 801 0.0 T 01-11-2018 IPR012300 Peptidase M6, InhA MLA2C4_03540 3e8c21e1722629fa836c1c7612640f11 801 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 190 499 1.1E-84 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_03540 3e8c21e1722629fa836c1c7612640f11 801 SUPERFAMILY SSF55486 268 437 2.45E-17 T 01-11-2018 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Gene3D G3DSA:1.10.268.10 367 455 1.1E-194 T 01-11-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Gene3D G3DSA:2.120.10.90 498 807 8.0E-98 T 01-11-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 SUPERFAMILY SSF56719 29 483 1.31E-167 T 01-11-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 SMART SM00434 9 462 9.5E-259 T 01-11-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Gene3D G3DSA:3.90.199.10 30 483 1.1E-194 T 01-11-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 6 744 0.0 T 01-11-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 5 803 33.941 T 01-11-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 517 1.5 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 753 5.0E-5 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 597 1.5E-4 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 696 8.7E-5 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 607 650 3.8E-6 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 SUPERFAMILY SSF101904 498 803 2.49E-90 T 01-11-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 469 6.7E-150 T 01-11-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_18680 9c97c6e19e8a5c57de9a71b1cb9d172c 807 Gene3D G3DSA:3.30.1360.40 234 330 1.1E-194 T 01-11-2018 MLA2C4_09260 d52b61392f5224b03b17ff118842cf40 287 Pfam PF13556 PucR C-terminal helix-turn-helix domain 225 281 5.5E-17 T 01-11-2018 IPR025736 PucR C-terminal helix-turn-helix domain MLA2C4_09260 d52b61392f5224b03b17ff118842cf40 287 SUPERFAMILY SSF46689 227 260 1.47E-6 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_09260 d52b61392f5224b03b17ff118842cf40 287 Gene3D G3DSA:1.10.10.2840 174 286 1.1E-14 T 01-11-2018 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 SUPERFAMILY SSF51230 3 96 1.15E-26 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 01-11-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 Gene3D G3DSA:4.10.320.10 111 164 7.4E-16 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 Gene3D G3DSA:3.30.559.10 190 437 6.3E-94 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 Pfam PF02817 e3 binding domain 120 154 4.0E-13 T 01-11-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 Gene3D G3DSA:2.40.50.100 1 103 6.2E-28 T 01-11-2018 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 Pfam PF00364 Biotin-requiring enzyme 5 77 1.6E-22 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 SUPERFAMILY SSF52777 208 428 4.45E-81 T 01-11-2018 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 SUPERFAMILY SSF47005 113 158 2.09E-12 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_21755 78ce044d11abb9158fdea07e9899a547 437 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 207 430 7.3E-79 T 01-11-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 SUPERFAMILY SSF53383 3 377 3.03E-124 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 Pfam PF00202 Aminotransferase class-III 14 378 1.5E-122 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 Gene3D G3DSA:3.40.640.10 48 287 3.5E-140 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 PIRSF PIRSF000521 11 115 2.0E-7 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 PIRSF PIRSF000521 108 150 0.022 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 PIRSF PIRSF000521 153 381 3.2E-40 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 Gene3D G3DSA:3.90.1150.10 18 370 3.5E-140 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 378 3.4E-152 T 01-11-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MLA2C4_21605 a0c1d8eda1c5a072b27075e1d2a9df81 386 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 4 381 69.67 T 01-11-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 9.7E-35 T 01-11-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 SMART SM01383 42 118 7.0E-48 T 01-11-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.412 T 01-11-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 Gene3D G3DSA:4.10.950.10 197 276 2.7E-38 T 01-11-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 SUPERFAMILY SSF50104 126 273 9.03E-62 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 Gene3D G3DSA:2.30.30.30 118 196 1.3E-34 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 Gene3D G3DSA:2.40.50.140 1 114 4.3E-49 T 01-11-2018 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 PIRSF PIRSF002158 3 276 3.5E-100 T 01-11-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 SMART SM01382 124 253 9.4E-94 T 01-11-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 4.6E-141 T 01-11-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 8.0E-58 T 01-11-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 01-11-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00690 dfd27e44c899db7aacf9fdb89ea997ea 276 SUPERFAMILY SSF50249 3 125 5.14E-51 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_18765 1d1a418d75083ad321f32bfe2bc86a3e 127 SUPERFAMILY SSF51735 48 118 8.99E-10 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_18765 1d1a418d75083ad321f32bfe2bc86a3e 127 Gene3D G3DSA:3.40.50.720 22 127 4.2E-20 T 01-11-2018 MLA2C4_18765 1d1a418d75083ad321f32bfe2bc86a3e 127 Pfam PF07993 Male sterility protein 51 122 4.8E-15 T 01-11-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MLA2C4_06750 3fb830766492e3a020e5abbafdf3bded 1000 Pfam PF00271 Helicase conserved C-terminal domain 755 830 2.2E-6 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_06750 3fb830766492e3a020e5abbafdf3bded 1000 SUPERFAMILY SSF52540 364 839 8.21E-19 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06750 3fb830766492e3a020e5abbafdf3bded 1000 SMART SM00490 737 831 0.0048 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_06750 3fb830766492e3a020e5abbafdf3bded 1000 Gene3D G3DSA:3.40.50.300 687 868 4.7E-9 T 01-11-2018 MLA2C4_09900 cc91b81108bcf161073e1d4bcc232c1d 333 Gene3D G3DSA:3.50.30.60 165 333 5.6E-65 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_09900 cc91b81108bcf161073e1d4bcc232c1d 333 SUPERFAMILY SSF52317 1 164 3.39E-47 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_09900 cc91b81108bcf161073e1d4bcc232c1d 333 SUPERFAMILY SSF141986 176 325 1.15E-41 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_09900 cc91b81108bcf161073e1d4bcc232c1d 333 PIRSF PIRSF028757 1 332 1.6E-89 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_09900 cc91b81108bcf161073e1d4bcc232c1d 333 Gene3D G3DSA:3.40.50.10740 1 164 2.5E-65 T 01-11-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal MLA2C4_09900 cc91b81108bcf161073e1d4bcc232c1d 333 Pfam PF02016 LD-carboxypeptidase 13 317 4.1E-73 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_03515 d2068f9ab3ab7891e8c78c663c3d5308 131 Gene3D G3DSA:3.40.1650.10 8 127 1.1E-37 T 01-11-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MLA2C4_03515 d2068f9ab3ab7891e8c78c663c3d5308 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 4.4E-48 T 01-11-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MLA2C4_03515 d2068f9ab3ab7891e8c78c663c3d5308 131 SUPERFAMILY SSF102546 1 131 2.62E-45 T 01-11-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MLA2C4_03515 d2068f9ab3ab7891e8c78c663c3d5308 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 32.605 T 01-11-2018 IPR023064 D-ribose pyranase GO:0016872 MLA2C4_03585 9ce685fd225df77df8fc7ed0c5b7695f 383 Pfam PF04892 VanZ like family 49 194 4.5E-23 T 01-11-2018 IPR006976 VanZ-like MLA2C4_03585 9ce685fd225df77df8fc7ed0c5b7695f 383 PIRSF PIRSF031578 1 383 4.1E-152 T 01-11-2018 IPR021192 Uncharacterised conserved protein UCP031578, VanZ/RDD-type MLA2C4_03585 9ce685fd225df77df8fc7ed0c5b7695f 383 Pfam PF06271 RDD family 215 369 1.7E-11 T 01-11-2018 IPR010432 RDD MLA2C4_13145 6545c293563dc26993fc9b58142d847d 66 SMART SM00530 6 61 2.9E-11 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_13145 6545c293563dc26993fc9b58142d847d 66 Gene3D G3DSA:1.10.260.40 3 66 1.5E-12 T 01-11-2018 MLA2C4_13145 6545c293563dc26993fc9b58142d847d 66 SUPERFAMILY SSF47413 1 64 6.48E-13 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_13145 6545c293563dc26993fc9b58142d847d 66 Pfam PF01381 Helix-turn-helix 13 61 2.3E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_26995 e03dddb505dd6258dc7de2f61214e7e2 126 SUPERFAMILY SSF54593 1 125 7.15E-19 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_26995 e03dddb505dd6258dc7de2f61214e7e2 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 116 1.7E-7 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_26995 e03dddb505dd6258dc7de2f61214e7e2 126 Gene3D G3DSA:3.10.180.10 1 125 1.2E-19 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 Gene3D G3DSA:1.10.287.130 207 299 3.9E-17 T 01-11-2018 MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 SMART SM00388 235 301 1.1E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 299 3.3E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 SMART SM00387 347 461 4.5E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 458 1.7E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 Gene3D G3DSA:3.30.565.10 316 463 3.5E-26 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 SUPERFAMILY SSF55874 291 459 8.91E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 SUPERFAMILY SSF47384 221 299 1.77E-15 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 2.5E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 2.5E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09945 fe7fa2d47e9501dcba5abc0eb22b3a14 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 2.5E-8 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 67 146 3.9E-34 T 01-11-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 117 123 - T 01-11-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 63 5.5E-5 T 01-11-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 SUPERFAMILY SSF53155 1 71 1.47E-17 T 01-11-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 69 148 1.3E-31 T 01-11-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 40.912 T 01-11-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 Gene3D G3DSA:3.30.160.70 1 62 1.7E-12 T 01-11-2018 MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 Gene3D G3DSA:1.10.10.10 66 149 1.2E-34 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10320 89a3fd26f5bc37889170295b128f44a5 150 SUPERFAMILY SSF46767 66 148 4.05E-31 T 01-11-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Gene3D G3DSA:3.40.50.670 405 640 2.7E-110 T 01-11-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 118 132 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 426 440 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 274 287 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 530 542 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 492 508 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 572 588 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR00418 DNA topoisomerase II family signature 510 527 1.0E-71 T 01-11-2018 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 640 101.778 T 01-11-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 366 380 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 318 334 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 380 400 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 476 485 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 PRINTS PR01159 DNA gyrase subunit B signature 226 248 1.1E-75 T 01-11-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 SMART SM00433 40 633 0.0 T 01-11-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 SMART SM00387 36 180 3.6E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Pfam PF00204 DNA gyrase B 227 396 9.7E-65 T 01-11-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 SUPERFAMILY SSF55874 11 219 1.96E-72 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Pfam PF01751 Toprim domain 425 536 2.5E-19 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Gene3D G3DSA:3.30.565.10 7 225 3.0E-91 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 SUPERFAMILY SSF54211 227 397 2.09E-63 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 179 9.3E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 01-11-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 7.8E-30 T 01-11-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 640 0.0 T 01-11-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 Gene3D G3DSA:3.30.230.10 226 404 3.7E-74 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_00025 140ae4f054ccb452193ce61e284a82f8 640 SUPERFAMILY SSF56719 400 632 1.2E-91 T 01-11-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 Gene3D G3DSA:3.30.70.660 107 244 2.6E-46 T 01-11-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 6.8E-63 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.942 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 SUPERFAMILY SSF55120 1 245 9.06E-79 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 Pfam PF01416 tRNA pseudouridine synthase 9 105 2.9E-10 T 01-11-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 4.7E-27 T 01-11-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 Gene3D G3DSA:3.30.70.580 1 106 2.0E-35 T 01-11-2018 MLA2C4_02550 5c9f144a74609ac063a73820c9c8b65f 245 PIRSF PIRSF001430 1 245 1.0E-81 T 01-11-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_27865 eb368bb98909980f7f9be92b10eec3e9 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 1.1E-10 T 01-11-2018 IPR009910 Protein of unknown function DUF1450 MLA2C4_27865 eb368bb98909980f7f9be92b10eec3e9 74 Hamap MF_01863 UPF0741 protein . 1 74 28.66 T 01-11-2018 IPR020880 Protein of unknown function UPF0741 MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 Pfam PF09339 IclR helix-turn-helix domain 7 55 9.0E-11 T 01-11-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 SUPERFAMILY SSF55781 60 248 1.5E-45 T 01-11-2018 MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 SMART SM00346 4 92 4.6E-22 T 01-11-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 Gene3D G3DSA:1.10.10.10 4 75 1.6E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 Pfam PF01614 Bacterial transcriptional regulator 120 244 1.8E-33 T 01-11-2018 IPR014757 Transcription regulator IclR, C-terminal MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 Gene3D G3DSA:3.30.450.40 76 249 4.8E-50 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_16190 b30c583e4de02a9ce7d747bda84aa70c 250 SUPERFAMILY SSF46785 6 75 1.13E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_14550 34d8988c8846b2e220a669062c288d53 389 SUPERFAMILY SSF53067 6 189 2.07E-5 T 01-11-2018 MLA2C4_14550 34d8988c8846b2e220a669062c288d53 389 SUPERFAMILY SSF53067 213 367 1.52E-12 T 01-11-2018 MLA2C4_14550 34d8988c8846b2e220a669062c288d53 389 Gene3D G3DSA:3.30.420.40 6 212 5.4E-12 T 01-11-2018 MLA2C4_14550 34d8988c8846b2e220a669062c288d53 389 Gene3D G3DSA:3.30.420.40 213 344 9.5E-11 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 1.4E-37 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 1.4E-37 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 1.4E-37 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 1.4E-37 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 1.4E-37 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 Gene3D G3DSA:3.40.50.880 164 360 9.4E-36 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 SMART SM01097 1 131 5.0E-89 T 01-11-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 8.0E-12 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 8.0E-12 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 326 339 8.0E-12 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 Pfam PF00117 Glutamine amidotransferase class-I 173 349 4.3E-47 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 3.0E-52 T 01-11-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 352 6.0E-147 T 01-11-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 SUPERFAMILY SSF52021 1 145 1.02E-57 T 01-11-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 SUPERFAMILY SSF52317 140 354 3.48E-58 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 355 48.788 T 01-11-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00097 Anthranilate synthase component II signature 213 222 6.0E-7 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00097 Anthranilate synthase component II signature 326 339 6.0E-7 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 PRINTS PR00097 Anthranilate synthase component II signature 240 251 6.0E-7 T 01-11-2018 MLA2C4_20320 f32b978daab2237b9a6b2eab5e9efc3d 365 Gene3D G3DSA:3.50.30.20 1 148 3.1E-56 T 01-11-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MLA2C4_18025 d4bd04c5731310d76930ac1041ac6944 441 Pfam PF03600 Citrate transporter 26 382 1.6E-50 T 01-11-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MLA2C4_18025 d4bd04c5731310d76930ac1041ac6944 441 PRINTS PR00758 Arsenical pump membrane protein signature 411 435 1.9E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_18025 d4bd04c5731310d76930ac1041ac6944 441 PRINTS PR00758 Arsenical pump membrane protein signature 227 252 1.9E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_18025 d4bd04c5731310d76930ac1041ac6944 441 PRINTS PR00758 Arsenical pump membrane protein signature 378 403 1.9E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_18025 d4bd04c5731310d76930ac1041ac6944 441 PRINTS PR00758 Arsenical pump membrane protein signature 286 310 1.9E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_18025 d4bd04c5731310d76930ac1041ac6944 441 PRINTS PR00758 Arsenical pump membrane protein signature 110 134 1.9E-10 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_10030 04930193710066c95280ea7d5e0c183b 767 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 397 722 2.7E-139 T 01-11-2018 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 MLA2C4_11400 3249866d35313ac4ba54801b49590216 333 SMART SM00382 45 232 1.8E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_11400 3249866d35313ac4ba54801b49590216 333 Pfam PF00005 ABC transporter 37 182 5.0E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_11400 3249866d35313ac4ba54801b49590216 333 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 32 316 1.3E-103 T 01-11-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 MLA2C4_11400 3249866d35313ac4ba54801b49590216 333 SUPERFAMILY SSF52540 19 260 1.16E-78 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11400 3249866d35313ac4ba54801b49590216 333 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_11400 3249866d35313ac4ba54801b49590216 333 Gene3D G3DSA:3.40.50.300 17 280 7.8E-79 T 01-11-2018 MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 98 5.6E-5 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 Gene3D G3DSA:3.40.50.720 145 251 2.0E-87 T 01-11-2018 MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 SUPERFAMILY SSF50129 1 161 2.28E-29 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 SMART SM00829 10 299 7.5E-10 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 Gene3D G3DSA:3.90.180.10 14 297 2.0E-87 T 01-11-2018 MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 Pfam PF00107 Zinc-binding dehydrogenase 166 256 3.5E-15 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_01030 c1d4479ba5e0235ac2d8897eea486f12 302 SUPERFAMILY SSF51735 127 253 4.46E-31 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Pfam PF00005 ABC transporter 334 469 1.4E-22 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 SUPERFAMILY SSF52540 4 240 1.63E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Gene3D G3DSA:1.10.287.380 551 629 1.8E-11 T 01-11-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 SMART SM00382 343 514 4.7E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 SMART SM00382 28 231 1.3E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Gene3D G3DSA:3.40.50.300 282 550 5.4E-63 T 01-11-2018 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Gene3D G3DSA:3.40.50.300 1 281 1.4E-73 T 01-11-2018 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Pfam PF16326 ABC transporter C-terminal domain 559 624 1.3E-17 T 01-11-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Pfam PF00005 ABC transporter 20 187 9.2E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 SUPERFAMILY SSF52540 313 516 1.57E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10945 ed09f12b0c75f542a06a5514ea8bccce 631 Pfam PF12848 ABC transporter 226 302 1.2E-16 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_22110 853c358ca5ee897595620f3b64847b24 447 Gene3D G3DSA:3.40.640.10 84 349 6.2E-169 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_22110 853c358ca5ee897595620f3b64847b24 447 Pfam PF02347 Glycine cleavage system P-protein 3 442 2.1E-163 T 01-11-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MLA2C4_22110 853c358ca5ee897595620f3b64847b24 447 PIRSF PIRSF006815 3 447 1.4E-192 T 01-11-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 MLA2C4_22110 853c358ca5ee897595620f3b64847b24 447 SUPERFAMILY SSF53383 3 445 5.46E-120 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22110 853c358ca5ee897595620f3b64847b24 447 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 51.694 T 01-11-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 MLA2C4_22110 853c358ca5ee897595620f3b64847b24 447 Gene3D G3DSA:3.90.1150.10 73 442 6.2E-169 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 111 3.1E-6 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 Pfam PF07724 AAA domain (Cdc48 subfamily) 191 349 3.5E-41 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 463 43.6 T 01-11-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 355 425 5.4E-7 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 Gene3D G3DSA:1.10.8.10 114 204 5.9E-5 T 01-11-2018 MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 Gene3D G3DSA:1.10.8.60 355 460 1.2E-39 T 01-11-2018 MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 SMART SM00382 50 352 1.1E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 SUPERFAMILY SSF52540 6 460 9.08E-88 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 SMART SM01086 355 449 3.2E-23 T 01-11-2018 IPR019489 Clp ATPase, C-terminal MLA2C4_20015 74caf6b4ba43dd15a6b9e3e18fb4fc2f 463 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 463 8.5E-210 T 01-11-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 PIRSF PIRSF001359 1 285 5.9E-125 T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 3.1E-113 T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 SUPERFAMILY SSF51569 1 285 5.71E-105 T 01-11-2018 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 4.7E-105 T 01-11-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 1.7E-129 T 01-11-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MLA2C4_27625 70f03a7a2527c9c9b5ecfdc6a29f896b 285 Gene3D G3DSA:3.20.20.70 1 285 4.6E-115 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 Gene3D G3DSA:2.30.30.40 60 124 3.6E-18 T 01-11-2018 MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 SUPERFAMILY SSF50685 401 443 4.88E-8 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 SMART SM00287 124 187 5.8E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 SMART SM00287 64 121 3.8E-8 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 Pfam PF08239 Bacterial SH3 domain 133 183 4.5E-9 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 Pfam PF08239 Bacterial SH3 domain 73 123 1.1E-12 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 Pfam PF06725 3D domain 404 463 2.7E-19 T 01-11-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MLA2C4_04375 d0c5e507c04b7bae28bbb118b1629c9b 463 Gene3D G3DSA:2.30.30.40 125 184 3.9E-14 T 01-11-2018 MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 Gene3D G3DSA:2.60.40.10 166 269 2.2E-16 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 Gene3D G3DSA:2.60.40.10 408 514 1.4E-20 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 518 548 1.0E-5 T 01-11-2018 MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 Gene3D G3DSA:2.60.40.740 270 407 1.2E-33 T 01-11-2018 MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 Gene3D G3DSA:2.60.40.10 23 162 4.5E-26 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 SUPERFAMILY SSF49478 171 242 8.63E-5 T 01-11-2018 MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 SUPERFAMILY SSF49478 420 479 3.92E-5 T 01-11-2018 MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 Pfam PF00746 LPXTG cell wall anchor motif 519 548 4.6E-5 T 01-11-2018 IPR019948 Gram-positive LPXTG cell wall anchor MLA2C4_08800 ffaf694b215cae4affda64eeadd28baf 553 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 263 384 2.3E-24 T 01-11-2018 IPR026466 Fimbrial isopeptide formation D2 domain MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 Gene3D G3DSA:1.10.287.130 182 259 3.0E-5 T 01-11-2018 MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 404 2.3E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 Gene3D G3DSA:3.30.565.10 260 406 2.4E-41 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 3.0E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 385 3.0E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 3.0E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 404 3.0E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 SMART SM00387 302 406 7.5E-29 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_24845 c8aba90d0de885fdf3ac69532c05549e 406 SUPERFAMILY SSF55874 258 405 3.67E-36 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 Gene3D G3DSA:1.10.60.40 328 413 5.9E-148 T 01-11-2018 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 Pfam PF00245 Alkaline phosphatase 44 450 2.9E-133 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 SMART SM00098 45 454 3.3E-197 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 Gene3D G3DSA:3.40.720.10 48 444 5.9E-148 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 ProSitePatterns PS00123 Alkaline phosphatase active site. 99 107 - T 01-11-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 PRINTS PR00113 Alkaline phosphatase signature 252 281 6.7E-45 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 PRINTS PR00113 Alkaline phosphatase signature 99 114 6.7E-45 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 PRINTS PR00113 Alkaline phosphatase signature 44 64 6.7E-45 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 PRINTS PR00113 Alkaline phosphatase signature 136 156 6.7E-45 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 PRINTS PR00113 Alkaline phosphatase signature 186 196 6.7E-45 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_22685 de38214e5bd26de93beb73b7da3620eb 461 SUPERFAMILY SSF53649 39 452 2.47E-130 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 Gene3D G3DSA:3.40.50.2000 167 313 8.4E-24 T 01-11-2018 MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 Gene3D G3DSA:3.40.50.2000 109 166 8.4E-24 T 01-11-2018 MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 Pfam PF00535 Glycosyl transferase family 2 370 514 5.8E-25 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 SUPERFAMILY SSF53756 7 363 1.15E-42 T 01-11-2018 MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 Pfam PF00534 Glycosyl transferases group 1 181 334 1.9E-13 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 SUPERFAMILY SSF53448 368 610 7.22E-41 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_01675 7cd7228d326a58cbb85bb4c060a1ad9a 643 Gene3D G3DSA:3.90.550.10 336 639 2.1E-43 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 Pfam PF00394 Multicopper oxidase 220 341 4.1E-6 T 01-11-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 SUPERFAMILY SSF49503 250 337 6.65E-13 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 Gene3D G3DSA:2.60.40.420 394 532 7.1E-38 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 Pfam PF07732 Multicopper oxidase 82 188 3.2E-37 T 01-11-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 ProSitePatterns PS00080 Multicopper oxidases signature 2. 507 518 - T 01-11-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 SUPERFAMILY SSF49503 398 522 3.87E-36 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 Pfam PF07731 Multicopper oxidase 420 522 1.1E-25 T 01-11-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 ProSitePatterns PS00079 Multicopper oxidases signature 1. 502 522 - T 01-11-2018 IPR033138 Multicopper oxidases, conserved site MLA2C4_09415 14c395fab7992cae95a2f6f1a8d9b10b 542 SUPERFAMILY SSF49503 62 188 1.4E-36 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 SUPERFAMILY SSF50249 1 63 1.09E-15 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 Gene3D G3DSA:3.40.50.300 62 225 4.4E-46 T 01-11-2018 MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 290 39.808 T 01-11-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 Gene3D G3DSA:1.10.40.50 226 293 3.1E-24 T 01-11-2018 MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 Gene3D G3DSA:2.40.50.140 1 61 7.3E-26 T 01-11-2018 MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 2.4E-87 T 01-11-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 Pfam PF03193 RsgA GTPase 59 225 8.1E-62 T 01-11-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 Pfam PF16745 RsgA N-terminal domain 3 56 1.2E-24 T 01-11-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal MLA2C4_20180 b997dcb0e37e14c0decfb162cf4cc881 293 SUPERFAMILY SSF52540 64 291 1.07E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 395 1.5E-165 T 01-11-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 SUPERFAMILY SSF53383 3 395 1.32E-125 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 Gene3D G3DSA:3.40.640.10 58 306 2.4E-156 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 68.432 T 01-11-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 Pfam PF00202 Aminotransferase class-III 15 395 1.7E-134 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 PIRSF PIRSF000521 175 396 4.4E-31 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 PIRSF PIRSF000521 2 160 2.1E-8 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_06050 61cba36a4dfeb7f005712c0dcd8fcd03 396 Gene3D G3DSA:3.90.1150.10 23 385 2.4E-156 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22300 913a3a66222b921a0141cea94d9abfd9 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.663 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22300 913a3a66222b921a0141cea94d9abfd9 49 SUPERFAMILY SSF57829 1 49 9.16E-18 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MLA2C4_22300 913a3a66222b921a0141cea94d9abfd9 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.3E-18 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22300 913a3a66222b921a0141cea94d9abfd9 49 Gene3D G3DSA:2.20.28.120 1 49 1.4E-22 T 01-11-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22300 913a3a66222b921a0141cea94d9abfd9 49 Pfam PF00471 Ribosomal protein L33 3 49 1.9E-20 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22300 913a3a66222b921a0141cea94d9abfd9 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 01-11-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 TIGRFAM TIGR01753 flav_short: flavodoxin 4 143 4.5E-46 T 01-11-2018 IPR010087 Flavodoxin, short chain GO:0010181 MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 Pfam PF00258 Flavodoxin 6 134 1.4E-28 T 01-11-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 SUPERFAMILY SSF52218 3 146 1.84E-39 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 PRINTS PR00369 Flavodoxin signature 5 18 4.6E-5 T 01-11-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 PRINTS PR00369 Flavodoxin signature 82 92 4.6E-5 T 01-11-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 PRINTS PR00369 Flavodoxin signature 53 64 4.6E-5 T 01-11-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MLA2C4_18385 27a0b636716898277f39d3e73a6dc283 147 Gene3D G3DSA:3.40.50.360 2 146 1.7E-37 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_11140 0f2c4d7aa96b2db315784feabf7ddadf 143 Gene3D G3DSA:3.40.630.30 2 143 2.0E-29 T 01-11-2018 MLA2C4_11140 0f2c4d7aa96b2db315784feabf7ddadf 143 Pfam PF00583 Acetyltransferase (GNAT) family 44 132 8.2E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_11140 0f2c4d7aa96b2db315784feabf7ddadf 143 SUPERFAMILY SSF55729 1 139 9.62E-27 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_23275 5d739f84072e20dbeebbea20ca75befe 277 Pfam PF01578 Cytochrome C assembly protein 71 270 8.6E-29 T 01-11-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 SUPERFAMILY SSF53474 2 293 1.27E-39 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 Gene3D G3DSA:3.40.50.1820 1 293 6.0E-43 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 4.7E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 4.7E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 4.7E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 PRINTS PR00412 Epoxide hydrolase signature 49 64 6.4E-7 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 PRINTS PR00412 Epoxide hydrolase signature 95 108 6.4E-7 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 PRINTS PR00412 Epoxide hydrolase signature 270 292 6.4E-7 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16735 1bf3aaaed9056a05c890ac282c32eb5e 294 Pfam PF12697 Alpha/beta hydrolase family 26 287 5.5E-19 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_23685 79c3d67f9716037abf00732ccf7c9c7d 44 Pfam PF14115 YuzL-like protein 4 43 1.7E-14 T 01-11-2018 IPR025625 YuzL-like protein MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 SUPERFAMILY SSF56601 1 264 2.32E-65 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 267 346 4.4E-6 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 58 69 2.5E-15 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 133 146 2.5E-15 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 106 123 2.5E-15 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 27 249 8.2E-67 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 Gene3D G3DSA:2.30.140.30 266 349 8.6E-9 T 01-11-2018 MLA2C4_07745 88336a4dcbab53189f10ae93e43e513f 374 Gene3D G3DSA:3.40.710.10 30 265 2.9E-86 T 01-11-2018 MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 218 294 9.2E-18 T 01-11-2018 IPR027470 Cation efflux protein, cytoplasmic domain MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 SUPERFAMILY SSF160240 218 295 5.75E-17 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 SUPERFAMILY SSF161111 7 214 1.7E-52 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 Gene3D G3DSA:1.20.1510.10 12 213 7.5E-62 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 294 5.4E-75 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 Gene3D G3DSA:3.30.70.1350 222 293 7.9E-15 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MLA2C4_22995 c47af7fb2afe4f697a56d57d48b5918c 297 Pfam PF01545 Cation efflux family 15 209 2.4E-45 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_14765 a0e190bbf13870341e9215a95355ef02 285 SUPERFAMILY SSF53850 26 284 2.81E-82 T 01-11-2018 MLA2C4_14765 a0e190bbf13870341e9215a95355ef02 285 Gene3D G3DSA:3.40.190.100 112 219 1.5E-93 T 01-11-2018 MLA2C4_14765 a0e190bbf13870341e9215a95355ef02 285 Gene3D G3DSA:3.40.190.10 32 283 1.5E-93 T 01-11-2018 MLA2C4_14765 a0e190bbf13870341e9215a95355ef02 285 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 274 1.0E-68 T 01-11-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MLA2C4_24440 48557712d2c59a080da70c838ecb9bcc 217 Gene3D G3DSA:3.40.50.150 1 213 5.8E-71 T 01-11-2018 MLA2C4_24440 48557712d2c59a080da70c838ecb9bcc 217 Pfam PF02390 Putative methyltransferase 39 206 1.5E-50 T 01-11-2018 MLA2C4_24440 48557712d2c59a080da70c838ecb9bcc 217 SUPERFAMILY SSF53335 25 209 1.17E-30 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_24440 48557712d2c59a080da70c838ecb9bcc 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.316 T 01-11-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MLA2C4_24440 48557712d2c59a080da70c838ecb9bcc 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 210 1.5E-62 T 01-11-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 SUPERFAMILY SSF46689 3 64 4.71E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.8E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.8E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 SUPERFAMILY SSF48498 81 188 7.12E-14 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 Gene3D G3DSA:1.10.357.10 71 191 7.3E-16 T 01-11-2018 MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 Gene3D G3DSA:1.10.10.60 1 65 2.3E-22 T 01-11-2018 MLA2C4_17370 9429fdb3274457e29aa3e192034219ba 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 2.3E-12 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_00855 68f3192017c1dc7235f958a056531555 237 SUPERFAMILY SSF53187 40 231 2.32E-51 T 01-11-2018 MLA2C4_00855 68f3192017c1dc7235f958a056531555 237 SMART SM00646 115 226 1.1E-30 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_00855 68f3192017c1dc7235f958a056531555 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 40 228 1.9E-83 T 01-11-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 MLA2C4_00855 68f3192017c1dc7235f958a056531555 237 Gene3D G3DSA:3.40.630.40 38 235 1.3E-53 T 01-11-2018 MLA2C4_00855 68f3192017c1dc7235f958a056531555 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 42 226 1.4E-46 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 Pfam PF00106 short chain dehydrogenase 3 193 5.8E-32 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 SUPERFAMILY SSF51735 2 226 9.04E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 Gene3D G3DSA:3.40.50.720 1 235 6.4E-41 T 01-11-2018 MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.2E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.2E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.2E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.2E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_04550 8d9617f6a0dcee6879b0f3c0d8c32098 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.2E-13 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17010 06f53323767709359c21f493e188ca67 223 Pfam PF00005 ABC transporter 24 173 9.9E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17010 06f53323767709359c21f493e188ca67 223 SUPERFAMILY SSF52540 4 222 4.39E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17010 06f53323767709359c21f493e188ca67 223 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17010 06f53323767709359c21f493e188ca67 223 Gene3D G3DSA:3.40.50.300 1 223 7.7E-70 T 01-11-2018 MLA2C4_17010 06f53323767709359c21f493e188ca67 223 SMART SM00382 33 220 1.3E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_12980 1ca4671ef9c225281afc9a5835763d97 213 Pfam PF13365 Trypsin-like peptidase domain 20 174 1.9E-14 T 01-11-2018 MLA2C4_12980 1ca4671ef9c225281afc9a5835763d97 213 Gene3D G3DSA:2.40.10.10 6 91 3.1E-6 T 01-11-2018 MLA2C4_12980 1ca4671ef9c225281afc9a5835763d97 213 Gene3D G3DSA:2.40.10.10 92 190 1.9E-8 T 01-11-2018 MLA2C4_12980 1ca4671ef9c225281afc9a5835763d97 213 SUPERFAMILY SSF50494 14 186 1.55E-23 T 01-11-2018 IPR009003 Peptidase S1, PA clan MLA2C4_21070 462c83132c181be1f3218b7dabe4d96c 255 SUPERFAMILY SSF158560 1 85 1.15E-17 T 01-11-2018 MLA2C4_17770 f30d37055568c33d0c7307d826ce6dff 131 Pfam PF03960 ArsC family 31 113 8.5E-23 T 01-11-2018 IPR006660 Arsenate reductase-like MLA2C4_17770 f30d37055568c33d0c7307d826ce6dff 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 36.999 T 01-11-2018 IPR023731 Regulatory protein Spx GO:0045892 MLA2C4_17770 f30d37055568c33d0c7307d826ce6dff 131 SUPERFAMILY SSF52833 1 125 7.66E-39 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_17770 f30d37055568c33d0c7307d826ce6dff 131 Gene3D G3DSA:3.40.30.10 1 120 1.5E-45 T 01-11-2018 MLA2C4_17770 f30d37055568c33d0c7307d826ce6dff 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 114 8.6E-37 T 01-11-2018 IPR006504 Transcriptional regulator Spx/MgsR MLA2C4_27480 babb0804708ac71a456fdbdeba815ba5 168 Hamap MF_01398 ATP synthase subunit b [atpF]. 9 146 13.228 T 01-11-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MLA2C4_27480 babb0804708ac71a456fdbdeba815ba5 168 Pfam PF00430 ATP synthase B/B' CF(0) 14 145 4.4E-37 T 01-11-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MLA2C4_27480 babb0804708ac71a456fdbdeba815ba5 168 SUPERFAMILY SSF81573 71 129 2.09E-7 T 01-11-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily MLA2C4_27480 babb0804708ac71a456fdbdeba815ba5 168 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 21 164 3.1E-39 T 01-11-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MLA2C4_04535 d4a83abb2181abf343d9bf7d39594205 303 SUPERFAMILY SSF103481 189 286 6.15E-16 T 01-11-2018 MLA2C4_04535 d4a83abb2181abf343d9bf7d39594205 303 Pfam PF00892 EamA-like transporter family 152 284 2.0E-29 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_04535 d4a83abb2181abf343d9bf7d39594205 303 Pfam PF00892 EamA-like transporter family 5 137 5.5E-29 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_04535 d4a83abb2181abf343d9bf7d39594205 303 SUPERFAMILY SSF103481 38 141 2.35E-18 T 01-11-2018 MLA2C4_08025 65a717c848a69e768a3310b40d1ed8ec 228 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 18 217 8.6E-42 T 01-11-2018 IPR010178 Integral membrane protein 1906 MLA2C4_08025 65a717c848a69e768a3310b40d1ed8ec 228 Pfam PF07314 Protein of unknown function (DUF1461) 19 190 2.5E-45 T 01-11-2018 IPR010178 Integral membrane protein 1906 MLA2C4_01240 c5b3ea2814870493005bdb0568ba07f1 177 SUPERFAMILY SSF53955 36 125 2.2E-11 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_01240 c5b3ea2814870493005bdb0568ba07f1 177 Gene3D G3DSA:1.10.530.10 30 171 8.2E-9 T 01-11-2018 MLA2C4_01240 c5b3ea2814870493005bdb0568ba07f1 177 Pfam PF01464 Transglycosylase SLT domain 46 126 1.2E-7 T 01-11-2018 IPR008258 Transglycosylase SLT domain 1 MLA2C4_04870 4961a22bd8f97430a65bba8eda98c661 153 Gene3D G3DSA:3.10.180.10 5 129 9.4E-21 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_04870 4961a22bd8f97430a65bba8eda98c661 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 126 7.3E-6 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_04870 4961a22bd8f97430a65bba8eda98c661 153 SUPERFAMILY SSF54593 9 130 4.34E-16 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15575 88d11d9422397ddf6445e1fdee665f7f 1180 Pfam PF13212 Domain of unknown function (DUF4020) 981 1156 1.8E-56 T 01-11-2018 IPR025093 Domain of unknown function DUF4020 MLA2C4_15575 88d11d9422397ddf6445e1fdee665f7f 1180 Pfam PF13289 SIR2-like domain 120 246 1.0E-16 T 01-11-2018 IPR039444 SIR2-like domain MLA2C4_15575 88d11d9422397ddf6445e1fdee665f7f 1180 SUPERFAMILY SSF52467 22 216 3.05E-14 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_25510 ad12ccd985686434a99f4abade899f3d 114 PRINTS PR00681 Ribosomal protein S1 signature 60 78 6.8E-12 T 01-11-2018 MLA2C4_25510 ad12ccd985686434a99f4abade899f3d 114 PRINTS PR00681 Ribosomal protein S1 signature 21 40 6.8E-12 T 01-11-2018 MLA2C4_25510 ad12ccd985686434a99f4abade899f3d 114 Pfam PF00575 S1 RNA binding domain 7 77 2.9E-20 T 01-11-2018 IPR003029 S1 domain GO:0003676 MLA2C4_25510 ad12ccd985686434a99f4abade899f3d 114 Gene3D G3DSA:2.40.50.140 2 85 4.8E-31 T 01-11-2018 MLA2C4_25510 ad12ccd985686434a99f4abade899f3d 114 SMART SM00316 6 77 3.4E-25 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_25510 ad12ccd985686434a99f4abade899f3d 114 SUPERFAMILY SSF50249 4 89 6.99E-25 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 370 1.1E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 SUPERFAMILY SSF47384 151 222 1.8E-11 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 Gene3D G3DSA:3.30.565.10 226 372 5.5E-34 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 6.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 6.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 6.5E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 SMART SM00387 266 372 9.2E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 Gene3D G3DSA:1.10.287.130 165 220 1.2E-10 T 01-11-2018 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 Pfam PF00512 His Kinase A (phospho-acceptor) domain 163 222 2.7E-10 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 SMART SM00388 162 224 3.3E-10 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 Gene3D G3DSA:1.10.490.70 6 159 4.2E-53 T 01-11-2018 IPR038284 Histidine kinase, N-terminal domain superfamily MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 SUPERFAMILY SSF55874 221 369 5.24E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_11455 3dd54154074896a84b1f97f21e8d70ca 372 Pfam PF09385 Histidine kinase N terminal 11 139 1.8E-49 T 01-11-2018 IPR018984 Histidine kinase, N-terminal MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 Gene3D G3DSA:3.40.50.720 5 224 3.1E-52 T 01-11-2018 MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 SUPERFAMILY SSF51735 7 211 2.77E-50 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.8E-10 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.8E-10 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.8E-10 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 Pfam PF00106 short chain dehydrogenase 8 192 1.4E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.9E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.9E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.9E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12070 565bfff61dde074d152788f6b9bfdf3c 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.9E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 SMART SM00418 9 87 8.6E-20 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 Gene3D G3DSA:1.10.10.10 2 107 5.2E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 Pfam PF12840 Helix-turn-helix domain 9 67 1.2E-11 T 01-11-2018 MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.8E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.8E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.8E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_24500 a3eb8bb90b11f16dd601f90237261427 107 SUPERFAMILY SSF46785 8 93 3.91E-25 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_24000 7298e31bbc28dab93fbb29ebbbc10a20 262 Pfam PF12746 GNAT acetyltransferase 19 254 3.3E-58 T 01-11-2018 IPR027365 GNAT acetyltransferase YdfB-like MLA2C4_24000 7298e31bbc28dab93fbb29ebbbc10a20 262 SUPERFAMILY SSF55729 130 246 7.15E-16 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_24000 7298e31bbc28dab93fbb29ebbbc10a20 262 Gene3D G3DSA:3.40.630.30 114 246 1.0E-37 T 01-11-2018 MLA2C4_14620 da57cff1fe712e24d5fc8fb8e7bf5f0f 203 SUPERFAMILY SSF48498 88 202 4.0E-26 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_14620 da57cff1fe712e24d5fc8fb8e7bf5f0f 203 Gene3D G3DSA:1.10.10.60 3 62 8.0E-13 T 01-11-2018 MLA2C4_14620 da57cff1fe712e24d5fc8fb8e7bf5f0f 203 Gene3D G3DSA:1.10.357.10 63 203 6.6E-30 T 01-11-2018 MLA2C4_14620 da57cff1fe712e24d5fc8fb8e7bf5f0f 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 4.3E-10 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_14620 da57cff1fe712e24d5fc8fb8e7bf5f0f 203 SUPERFAMILY SSF46689 8 80 1.64E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_11280 ffff7b656751ff6e4b9872103c28f6a4 320 Gene3D G3DSA:3.40.50.1980 39 144 7.3E-33 T 01-11-2018 MLA2C4_11280 ffff7b656751ff6e4b9872103c28f6a4 320 Pfam PF01497 Periplasmic binding protein 58 294 1.3E-30 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_11280 ffff7b656751ff6e4b9872103c28f6a4 320 SUPERFAMILY SSF53807 41 314 4.91E-66 T 01-11-2018 MLA2C4_11280 ffff7b656751ff6e4b9872103c28f6a4 320 Gene3D G3DSA:3.40.50.1980 145 320 8.0E-66 T 01-11-2018 MLA2C4_14800 36b770eab3869628673df931135247ef 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 395 3.0E-113 T 01-11-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 MLA2C4_14800 36b770eab3869628673df931135247ef 397 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 228 375 2.0E-23 T 01-11-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 MLA2C4_14800 36b770eab3869628673df931135247ef 397 SUPERFAMILY SSF53756 3 394 3.14E-77 T 01-11-2018 MLA2C4_14800 36b770eab3869628673df931135247ef 397 Gene3D G3DSA:3.40.50.2000 5 391 8.6E-121 T 01-11-2018 MLA2C4_14800 36b770eab3869628673df931135247ef 397 Gene3D G3DSA:3.40.50.2000 217 380 8.6E-121 T 01-11-2018 MLA2C4_19260 fafb9adcab9136e0947079c3de516e5c 387 Gene3D G3DSA:3.40.640.10 1 254 9.7E-87 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_19260 fafb9adcab9136e0947079c3de516e5c 387 PIRSF PIRSF000390 5 387 6.8E-108 T 01-11-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MLA2C4_19260 fafb9adcab9136e0947079c3de516e5c 387 SUPERFAMILY SSF53383 14 383 6.95E-102 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_19260 fafb9adcab9136e0947079c3de516e5c 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 379 1.0E-97 T 01-11-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MLA2C4_19260 fafb9adcab9136e0947079c3de516e5c 387 Gene3D G3DSA:3.90.1150.10 256 387 4.7E-38 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 PIRSF PIRSF000446 1 311 2.2E-117 T 01-11-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 SUPERFAMILY SSF52151 4 307 4.19E-80 T 01-11-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 1.2E-50 T 01-11-2018 IPR020801 Polyketide synthase, acyl transferase domain MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 Pfam PF00698 Acyl transferase domain 6 282 2.3E-43 T 01-11-2018 IPR014043 Acyl transferase MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 Gene3D G3DSA:3.30.70.250 126 199 4.6E-98 T 01-11-2018 MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 SUPERFAMILY SSF55048 128 193 4.84E-14 T 01-11-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 6.7E-113 T 01-11-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MLA2C4_20130 03f710b7fb36d6f69ac84c608196edf0 314 Gene3D G3DSA:3.40.366.10 6 285 4.6E-98 T 01-11-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 MLA2C4_02240 04b99523a9bea5968a245181d1795bb1 411 Pfam PF00202 Aminotransferase class-III 21 407 2.2E-59 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_02240 04b99523a9bea5968a245181d1795bb1 411 Gene3D G3DSA:3.90.1150.10 22 406 2.3E-78 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_02240 04b99523a9bea5968a245181d1795bb1 411 Gene3D G3DSA:3.40.640.10 55 321 2.3E-78 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_02240 04b99523a9bea5968a245181d1795bb1 411 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 268 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_02240 04b99523a9bea5968a245181d1795bb1 411 SUPERFAMILY SSF53383 13 407 3.93E-74 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 Pfam PF13444 Acetyltransferase (GNAT) domain 20 112 1.2E-10 T 01-11-2018 MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 Gene3D G3DSA:3.40.630.30 3 163 1.5E-17 T 01-11-2018 MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 SUPERFAMILY SSF55729 5 162 3.12E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 Gene3D G3DSA:3.40.640.10 192 424 9.3E-75 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 Pfam PF00266 Aminotransferase class-V 201 480 1.7E-14 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 SUPERFAMILY SSF53383 182 519 6.29E-57 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_12775 5d9810dd0e269ca01b140063f3660ff3 527 Gene3D G3DSA:3.90.1150.10 184 517 9.3E-75 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_23205 624447980f56568e1bfdaf2dfc6de0b2 283 Gene3D G3DSA:2.40.10.350 186 261 3.3E-30 T 01-11-2018 MLA2C4_23205 624447980f56568e1bfdaf2dfc6de0b2 283 Pfam PF04085 rod shape-determining protein MreC 123 273 1.1E-43 T 01-11-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MLA2C4_23205 624447980f56568e1bfdaf2dfc6de0b2 283 PIRSF PIRSF038471 2 283 1.1E-63 T 01-11-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MLA2C4_23205 624447980f56568e1bfdaf2dfc6de0b2 283 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 7 276 3.8E-60 T 01-11-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MLA2C4_23205 624447980f56568e1bfdaf2dfc6de0b2 283 Gene3D G3DSA:2.40.10.340 114 185 1.1E-24 T 01-11-2018 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 356 398 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 SUPERFAMILY SSF46689 304 353 1.52E-6 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 Gene3D G3DSA:1.10.10.60 353 406 2.8E-17 T 01-11-2018 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 SMART SM00342 319 402 2.7E-29 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 Pfam PF12833 Helix-turn-helix domain 325 403 6.0E-20 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 Gene3D G3DSA:1.10.10.60 299 352 1.9E-12 T 01-11-2018 MLA2C4_13570 333b5e30af11931c7327be23889d1cd3 408 SUPERFAMILY SSF46689 356 406 1.12E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 Pfam PF07690 Major Facilitator Superfamily 15 406 4.1E-58 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 487 6.6E-88 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 Gene3D G3DSA:1.20.1250.20 263 498 3.7E-20 T 01-11-2018 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 SUPERFAMILY SSF103473 9 503 4.01E-79 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 8.4E-6 T 01-11-2018 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 355 375 8.4E-6 T 01-11-2018 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 8.4E-6 T 01-11-2018 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 8.4E-6 T 01-11-2018 MLA2C4_15240 ad18861b1d17972e607d4d184585a908 511 Gene3D G3DSA:1.20.1720.10 12 214 2.5E-55 T 01-11-2018 MLA2C4_25905 37e9095b37896162a880fc2e2ae442c7 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 8.2E-76 T 01-11-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MLA2C4_25905 37e9095b37896162a880fc2e2ae442c7 465 SUPERFAMILY SSF101960 32 462 1.03E-139 T 01-11-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily MLA2C4_25905 37e9095b37896162a880fc2e2ae442c7 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 1.3E-231 T 01-11-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MLA2C4_18395 da3f6e6fa13f6ac24f686f91995ae8e6 131 Gene3D G3DSA:3.90.79.10 1 128 1.5E-23 T 01-11-2018 MLA2C4_18395 da3f6e6fa13f6ac24f686f91995ae8e6 131 Pfam PF00293 NUDIX domain 3 116 8.8E-15 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_18395 da3f6e6fa13f6ac24f686f91995ae8e6 131 SUPERFAMILY SSF55811 7 122 2.03E-23 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_18395 da3f6e6fa13f6ac24f686f91995ae8e6 131 PRINTS PR00502 NUDIX hydrolase family signature 29 43 1.2E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_18395 da3f6e6fa13f6ac24f686f91995ae8e6 131 PRINTS PR00502 NUDIX hydrolase family signature 43 58 1.2E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 Pfam PF01259 SAICAR synthetase 7 232 1.6E-67 T 01-11-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 01-11-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 Gene3D G3DSA:3.30.470.20 85 221 2.6E-96 T 01-11-2018 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 Gene3D G3DSA:3.30.200.20 7 232 2.6E-96 T 01-11-2018 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 34.159 T 01-11-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 SUPERFAMILY SSF56104 1 236 6.21E-85 T 01-11-2018 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 01-11-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01760 0c053c74966b7d6ccf73e2413069267e 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 236 4.1E-78 T 01-11-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 SMART SM00382 33 232 1.7E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 Gene3D G3DSA:3.40.50.300 1 335 3.3E-95 T 01-11-2018 MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 Pfam PF00005 ABC transporter 25 182 2.3E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 2.2E-17 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.0E-23 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01090 352608389a5976e4598a3cb6ca3b64bf 336 SUPERFAMILY SSF52540 4 254 4.95E-65 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 7.9E-54 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 Gene3D G3DSA:2.40.150.20 1 122 4.4E-53 T 01-11-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.791 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 SMART SM01374 1 122 1.9E-86 T 01-11-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 SUPERFAMILY SSF50193 1 122 3.01E-50 T 01-11-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.8E-57 T 01-11-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MLA2C4_00725 1eb48b86857d2cdaf3958ecbace7a682 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 01-11-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 PRINTS PR00421 Thioredoxin family signature 28 37 7.7E-7 T 01-11-2018 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 PRINTS PR00421 Thioredoxin family signature 20 28 7.7E-7 T 01-11-2018 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 PRINTS PR00421 Thioredoxin family signature 68 79 7.7E-7 T 01-11-2018 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 3.4E-37 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 SUPERFAMILY SSF52833 3 103 2.03E-35 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 01-11-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 Gene3D G3DSA:3.40.30.10 1 104 1.4E-34 T 01-11-2018 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 PIRSF PIRSF000077 1 104 1.2E-40 T 01-11-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MLA2C4_23505 d6c2fa8c35f2921db86f13895c0e19b1 104 Pfam PF00085 Thioredoxin 4 103 5.2E-30 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 MLA2C4_07110 bc4765b9334bdd8338620d5174ecbcf1 220 PIRSF PIRSF006293 2 218 7.5E-78 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MLA2C4_07110 bc4765b9334bdd8338620d5174ecbcf1 220 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 9.8E-86 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MLA2C4_07110 bc4765b9334bdd8338620d5174ecbcf1 220 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 3.2E-84 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MLA2C4_07110 bc4765b9334bdd8338620d5174ecbcf1 220 SUPERFAMILY SSF52402 3 211 1.08E-69 T 01-11-2018 MLA2C4_07110 bc4765b9334bdd8338620d5174ecbcf1 220 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 217 52.325 T 01-11-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MLA2C4_07110 bc4765b9334bdd8338620d5174ecbcf1 220 Gene3D G3DSA:3.40.50.620 1 218 8.6E-75 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_08190 81dc89481ccda2340690d9bc892a4a54 112 Pfam PF05103 DivIVA protein 8 91 4.2E-20 T 01-11-2018 IPR007793 DivIVA family MLA2C4_08190 81dc89481ccda2340690d9bc892a4a54 112 PIRSF PIRSF029938 1 112 6.2E-49 T 01-11-2018 IPR011229 Cell cycle protein GpsB MLA2C4_08190 81dc89481ccda2340690d9bc892a4a54 112 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 108 23.638 T 01-11-2018 IPR011229 Cell cycle protein GpsB MLA2C4_08190 81dc89481ccda2340690d9bc892a4a54 112 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 4.0E-16 T 01-11-2018 IPR019933 DivIVA domain MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 200 3.0E-9 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Gene3D G3DSA:3.30.70.250 1 84 1.4E-37 T 01-11-2018 MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 SUPERFAMILY SSF51161 88 226 1.7E-51 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 2.8E-117 T 01-11-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 1.1E-35 T 01-11-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Gene3D G3DSA:2.160.10.10 85 236 4.3E-52 T 01-11-2018 MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 46.388 T 01-11-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 5.5E-10 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_20810 c697f9bec6c8cae5fa44dd8fd165d479 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 119 2.5E-5 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 Pfam PF01012 Electron transfer flavoprotein domain 5 179 3.6E-43 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 SMART SM00893 5 195 3.2E-45 T 01-11-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 01-11-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 Gene3D G3DSA:3.40.50.620 1 194 3.4E-54 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 SUPERFAMILY SSF52467 198 317 1.5E-48 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 Gene3D G3DSA:3.40.50.1220 195 325 3.5E-57 T 01-11-2018 MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 PIRSF PIRSF000089 1 323 7.4E-113 T 01-11-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 SUPERFAMILY SSF52402 4 191 4.67E-50 T 01-11-2018 MLA2C4_23510 3e2403f758e9d8eef6d3bb0b602231ea 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 1.4E-35 T 01-11-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 117 1.7E-19 T 01-11-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 3.1E-15 T 01-11-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 3.1E-15 T 01-11-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 34 53 3.1E-15 T 01-11-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 3.1E-15 T 01-11-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 Pfam PF00361 Proton-conducting membrane transporter 130 419 3.5E-91 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 612 2.6E-202 T 01-11-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 5.1E-60 T 01-11-2018 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 5.1E-60 T 01-11-2018 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 5.1E-60 T 01-11-2018 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 5.1E-60 T 01-11-2018 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 5.1E-60 T 01-11-2018 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 5.1E-60 T 01-11-2018 MLA2C4_27395 3fc3a4ef5dca36551df587e441544431 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 5.1E-60 T 01-11-2018 MLA2C4_17045 52a70f0b60cb39ead14df0e34c35b815 279 Gene3D G3DSA:3.30.70.120 188 263 9.7E-23 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_17045 52a70f0b60cb39ead14df0e34c35b815 279 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 2.9E-60 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_17045 52a70f0b60cb39ead14df0e34c35b815 279 PIRSF PIRSF006483 1 278 6.7E-82 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_17045 52a70f0b60cb39ead14df0e34c35b815 279 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 4.9E-22 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_07250 efdb19d9be85f1335a9012514f4b4cb3 385 Pfam PF01385 Probable transposase 168 296 2.8E-13 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_07250 efdb19d9be85f1335a9012514f4b4cb3 385 Pfam PF12323 Helix-turn-helix domain 1 46 6.1E-17 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_07250 efdb19d9be85f1335a9012514f4b4cb3 385 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 267 336 2.4E-9 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_07250 efdb19d9be85f1335a9012514f4b4cb3 385 Pfam PF07282 Putative transposase DNA-binding domain 309 377 2.4E-22 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_06235 67d756f065a5e22c083328dd1c902e02 311 Pfam PF00005 ABC transporter 29 181 9.2E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_06235 67d756f065a5e22c083328dd1c902e02 311 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_06235 67d756f065a5e22c083328dd1c902e02 311 Gene3D G3DSA:3.40.50.300 6 310 6.6E-95 T 01-11-2018 MLA2C4_06235 67d756f065a5e22c083328dd1c902e02 311 SMART SM00382 37 231 4.1E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_06235 67d756f065a5e22c083328dd1c902e02 311 SUPERFAMILY SSF52540 8 253 4.6E-77 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06235 67d756f065a5e22c083328dd1c902e02 311 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 272 1.2E-6 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_27190 7a229616dd656706dc8535ca4b538f87 344 Gene3D G3DSA:3.40.190.10 142 262 4.9E-71 T 01-11-2018 MLA2C4_27190 7a229616dd656706dc8535ca4b538f87 344 Gene3D G3DSA:3.40.190.10 45 314 4.9E-71 T 01-11-2018 MLA2C4_27190 7a229616dd656706dc8535ca4b538f87 344 SUPERFAMILY SSF53850 42 307 9.83E-52 T 01-11-2018 MLA2C4_27190 7a229616dd656706dc8535ca4b538f87 344 Pfam PF13343 Bacterial extracellular solute-binding protein 88 329 9.4E-53 T 01-11-2018 MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 Pfam PF00202 Aminotransferase class-III 36 402 5.4E-72 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 Gene3D G3DSA:3.90.1150.10 9 423 1.5E-171 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 Gene3D G3DSA:3.40.640.10 72 320 1.5E-171 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 95.505 T 01-11-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 SUPERFAMILY SSF53383 2 426 1.75E-124 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 426 1.5E-168 T 01-11-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MLA2C4_02755 263a35683229dd499e3f1a10835916c2 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_17290 6122b8c29ed5aa0fa4fbd4cde2e21d52 448 Pfam PF02667 Short chain fatty acid transporter 4 447 2.3E-164 T 01-11-2018 IPR006160 Short chain fatty acid transporter AtoE MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Gene3D G3DSA:1.20.58.1950 226 277 3.9E-24 T 01-11-2018 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 ProSitePatterns PS00654 PRD domain signature. 102 114 - T 01-11-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Gene3D G3DSA:1.20.890.100 170 224 4.4E-21 T 01-11-2018 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Pfam PF03123 CAT RNA binding domain 6 60 8.4E-24 T 01-11-2018 IPR004341 CAT RNA-binding domain GO:0003723 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 SUPERFAMILY SSF50151 6 57 3.53E-17 T 01-11-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Pfam PF00874 PRD domain 80 166 2.0E-24 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Pfam PF00874 PRD domain 185 275 1.5E-21 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 SUPERFAMILY SSF63520 181 277 9.16E-25 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 SMART SM01061 5 63 1.0E-27 T 01-11-2018 IPR004341 CAT RNA-binding domain GO:0003723 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Gene3D G3DSA:2.30.24.10 1 70 7.8E-26 T 01-11-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 SUPERFAMILY SSF63520 60 171 5.75E-31 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_21185 007dc0f2702a803ba20395b9d8030ddf 282 Gene3D G3DSA:1.10.1790.10 71 169 6.2E-32 T 01-11-2018 MLA2C4_24575 c4148eccf50941421fb889709d2395c0 337 Pfam PF00899 ThiF family 5 240 1.4E-63 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MLA2C4_24575 c4148eccf50941421fb889709d2395c0 337 SUPERFAMILY SSF69572 3 329 1.57E-88 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_24575 c4148eccf50941421fb889709d2395c0 337 Gene3D G3DSA:3.40.50.720 1 248 4.1E-76 T 01-11-2018 MLA2C4_20630 2e94554acaefca9fd28bedcad429be9b 95 Gene3D G3DSA:1.10.287.750 3 93 3.8E-38 T 01-11-2018 IPR036270 UPF0358 superfamily MLA2C4_20630 2e94554acaefca9fd28bedcad429be9b 95 SUPERFAMILY SSF140404 6 84 4.18E-37 T 01-11-2018 IPR036270 UPF0358 superfamily MLA2C4_20630 2e94554acaefca9fd28bedcad429be9b 95 Hamap MF_01560 UPF0358 protein . 3 93 27.869 T 01-11-2018 IPR009983 Uncharacterised protein family UPF0358 MLA2C4_20630 2e94554acaefca9fd28bedcad429be9b 95 Pfam PF07408 Protein of unknown function (DUF1507) 9 91 7.7E-42 T 01-11-2018 IPR009983 Uncharacterised protein family UPF0358 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 271 8.2E-26 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 8.2E-26 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 8.2E-26 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 297 8.2E-26 T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 310 80.893 T 01-11-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 Gene3D G3DSA:3.40.50.1370 13 305 4.3E-130 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 4.6E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 4.6E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 4.6E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 288 299 4.6E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 4.6E-30 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 Gene3D G3DSA:3.40.50.1370 138 296 4.3E-130 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 148 3.8E-50 T 01-11-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 SUPERFAMILY SSF53671 9 312 5.5E-107 T 01-11-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 309 3.5E-129 T 01-11-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 01-11-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MLA2C4_21600 3fe22891f37176047e6744e661c4311a 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 307 3.2E-55 T 01-11-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 121 176 8.8E-30 T 01-11-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 Gene3D G3DSA:3.30.505.50 134 180 2.5E-27 T 01-11-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 180 25.332 T 01-11-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 3.1E-32 T 01-11-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 1.4E-34 T 01-11-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 SUPERFAMILY SSF69754 2 103 8.37E-37 T 01-11-2018 IPR036567 Ribosome hibernation promotion factor-like MLA2C4_26850 26196f2773fe1a57fad7580012654ce0 180 Gene3D G3DSA:3.30.160.100 1 95 4.6E-35 T 01-11-2018 IPR036567 Ribosome hibernation promotion factor-like MLA2C4_07450 0a4c6985c64e56cb904cd4d4de142253 239 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 231 1.4E-86 T 01-11-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MLA2C4_07450 0a4c6985c64e56cb904cd4d4de142253 239 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 36.386 T 01-11-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MLA2C4_07450 0a4c6985c64e56cb904cd4d4de142253 239 SUPERFAMILY SSF51366 1 235 4.04E-73 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_07450 0a4c6985c64e56cb904cd4d4de142253 239 Pfam PF00977 Histidine biosynthesis protein 2 227 4.7E-79 T 01-11-2018 IPR006062 Histidine biosynthesis GO:0000105 MLA2C4_07450 0a4c6985c64e56cb904cd4d4de142253 239 Gene3D G3DSA:3.20.20.70 3 238 1.0E-86 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_26355 4c1c023492012be59fddd6777d30b1cc 309 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 91 127 2.0E-11 T 01-11-2018 IPR023849 Uncharacterised domain CHP03934, TQXA MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 01-11-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 SMART SM00493 80 165 5.0E-18 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 Pfam PF13662 Toprim domain 80 171 2.2E-26 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 Gene3D G3DSA:3.40.1360.10 77 198 5.2E-50 T 01-11-2018 MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 SUPERFAMILY SSF111304 1 198 7.59E-79 T 01-11-2018 IPR023627 Recombination protein RecR MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 110.715 T 01-11-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 Pfam PF02132 RecR protein 40 78 1.3E-15 T 01-11-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 1.1E-89 T 01-11-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MLA2C4_00135 afe8522e188a776f0963e6f685da783b 198 Gene3D G3DSA:1.10.8.420 1 53 1.6E-20 T 01-11-2018 MLA2C4_22570 5205a0ea67acec0e9230c87a8ccc9cd6 85 Pfam PF01649 Ribosomal protein S20 2 84 1.4E-25 T 01-11-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_22570 5205a0ea67acec0e9230c87a8ccc9cd6 85 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.821 T 01-11-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_22570 5205a0ea67acec0e9230c87a8ccc9cd6 85 SUPERFAMILY SSF46992 3 85 3.4E-28 T 01-11-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_22570 5205a0ea67acec0e9230c87a8ccc9cd6 85 Gene3D G3DSA:1.20.58.110 1 85 1.9E-28 T 01-11-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_22570 5205a0ea67acec0e9230c87a8ccc9cd6 85 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 1.0E-28 T 01-11-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_22570 5205a0ea67acec0e9230c87a8ccc9cd6 85 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 84 6.0E-33 T 01-11-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20340 2f1f86eb43ca61078d5e1821eceb14d1 180 Pfam PF00156 Phosphoribosyl transferase domain 8 163 1.1E-20 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_20340 2f1f86eb43ca61078d5e1821eceb14d1 180 Gene3D G3DSA:3.40.50.2020 1 180 7.2E-63 T 01-11-2018 MLA2C4_20340 2f1f86eb43ca61078d5e1821eceb14d1 180 SUPERFAMILY SSF53271 6 174 3.15E-44 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_20340 2f1f86eb43ca61078d5e1821eceb14d1 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 39.353 T 01-11-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 Gene3D G3DSA:3.40.50.720 24 301 1.0E-73 T 01-11-2018 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 94 272 5.2E-42 T 01-11-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 304 3.2E-19 T 01-11-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 Gene3D G3DSA:3.30.70.260 306 389 1.0E-19 T 01-11-2018 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 138 165 - T 01-11-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 SUPERFAMILY SSF51735 83 273 7.48E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 SUPERFAMILY SSF55021 307 389 6.47E-16 T 01-11-2018 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 SUPERFAMILY SSF52283 21 105 6.99E-21 T 01-11-2018 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 Gene3D G3DSA:3.40.50.720 84 276 1.0E-73 T 01-11-2018 MLA2C4_17110 487c787c53345648eadd6810f4e24953 390 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 01-11-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MLA2C4_18500 5d0028bd851a4bc2e074bb849e83d5a2 78 Pfam PF02597 ThiS family 4 78 1.2E-18 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MLA2C4_18500 5d0028bd851a4bc2e074bb849e83d5a2 78 SUPERFAMILY SSF54285 1 78 1.32E-16 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MLA2C4_18500 5d0028bd851a4bc2e074bb849e83d5a2 78 Gene3D G3DSA:3.10.20.30 1 78 5.1E-20 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_18500 5d0028bd851a4bc2e074bb849e83d5a2 78 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 78 1.3E-22 T 01-11-2018 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 196 222 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 PIRSF PIRSF000770 2 237 1.4E-92 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 Gene3D G3DSA:1.10.10.10 159 235 1.5E-14 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 211 222 7.6E-14 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 77 90 7.6E-14 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 196 211 7.6E-14 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 175 187 7.6E-14 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 Gene3D G3DSA:1.20.120.1810 19 119 4.2E-24 T 01-11-2018 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 222 1.6E-30 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 Pfam PF04545 Sigma-70, region 4 172 222 2.9E-16 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 Pfam PF04542 Sigma-70 region 2 53 120 1.9E-17 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 SUPERFAMILY SSF88946 10 118 8.9E-34 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 SUPERFAMILY SSF88659 138 223 2.24E-19 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_22655 27dce26354d3e86b8e4f9c675754002d 237 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 3 226 1.1E-112 T 01-11-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_22330 487eae6f7638cfeeaee234dbcf314c3c 305 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 13 288 5.0E-83 T 01-11-2018 IPR011862 Phosphate binding protein GO:0042301 MLA2C4_22330 487eae6f7638cfeeaee234dbcf314c3c 305 Pfam PF12849 PBP superfamily domain 27 272 3.1E-25 T 01-11-2018 IPR024370 PBP domain MLA2C4_22330 487eae6f7638cfeeaee234dbcf314c3c 305 SUPERFAMILY SSF53850 23 303 1.37E-66 T 01-11-2018 MLA2C4_22330 487eae6f7638cfeeaee234dbcf314c3c 305 Gene3D G3DSA:3.40.190.10 34 286 1.3E-80 T 01-11-2018 MLA2C4_22330 487eae6f7638cfeeaee234dbcf314c3c 305 Gene3D G3DSA:3.40.190.10 113 249 1.3E-80 T 01-11-2018 MLA2C4_05295 d41c76d47fdf3176d143745d21c946ec 66 Pfam PF05532 CsbD-like 8 60 1.5E-14 T 01-11-2018 IPR008462 CsbD-like domain MLA2C4_05295 d41c76d47fdf3176d143745d21c946ec 66 SUPERFAMILY SSF69047 7 63 1.7E-11 T 01-11-2018 IPR036629 YjbJ superfamily MLA2C4_05295 d41c76d47fdf3176d143745d21c946ec 66 Gene3D G3DSA:1.10.1470.10 7 65 1.9E-7 T 01-11-2018 IPR036629 YjbJ superfamily MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 SUPERFAMILY SSF55973 125 246 6.28E-53 T 01-11-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Gene3D G3DSA:3.30.300.10 7 247 3.6E-181 T 01-11-2018 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 01-11-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 1.4E-185 T 01-11-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 PIRSF PIRSF000497 1 398 1.7E-177 T 01-11-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Gene3D G3DSA:3.30.300.10 13 284 3.6E-181 T 01-11-2018 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Gene3D G3DSA:3.30.300.10 104 389 3.6E-181 T 01-11-2018 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 SUPERFAMILY SSF55973 5 111 2.28E-47 T 01-11-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 SUPERFAMILY SSF55973 247 397 2.32E-70 T 01-11-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 6.7E-70 T 01-11-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 1.1E-49 T 01-11-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 58.779 T 01-11-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 7.2E-44 T 01-11-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_24810 32cc05fd7f0dc50950c88a71b87b8219 399 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 01-11-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 4.6E-65 T 01-11-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 3.5E-142 T 01-11-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 Gene3D G3DSA:1.10.3730.40 182 333 4.6E-69 T 01-11-2018 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 SUPERFAMILY SSF51735 3 182 9.69E-74 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 45.583 T 01-11-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 Gene3D G3DSA:3.40.50.720 1 181 1.4E-79 T 01-11-2018 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 PIRSF PIRSF000116 1 205 1.0E-40 T 01-11-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 PIRSF PIRSF000116 201 331 4.9E-13 T 01-11-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 SUPERFAMILY SSF48179 183 328 5.78E-69 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_07400 3547e86f93d4381c47a5d38f73eb332d 336 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 2.2E-78 T 01-11-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_00205 5b74d7fb834c0c1a04375ca370e7ceea 246 SUPERFAMILY SSF53335 13 197 1.79E-29 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_00205 5b74d7fb834c0c1a04375ca370e7ceea 246 Gene3D G3DSA:3.40.50.150 7 246 1.4E-70 T 01-11-2018 MLA2C4_00205 5b74d7fb834c0c1a04375ca370e7ceea 246 Pfam PF05175 Methyltransferase small domain 33 143 1.5E-7 T 01-11-2018 IPR007848 Methyltransferase small domain GO:0008168 MLA2C4_17710 ff0fd25244a2fffccf55d5354f5665b6 353 Pfam PF10282 Lactonase, 7-bladed beta-propeller 10 350 4.0E-133 T 01-11-2018 IPR019405 Lactonase, 7-bladed beta propeller MLA2C4_17710 ff0fd25244a2fffccf55d5354f5665b6 353 Gene3D G3DSA:2.130.10.10 8 353 2.4E-127 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MLA2C4_17710 ff0fd25244a2fffccf55d5354f5665b6 353 SUPERFAMILY SSF51004 17 352 1.7E-51 T 01-11-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily MLA2C4_03750 ec3a14ccab6714d637c938bf63695425 240 Pfam PF02421 Ferrous iron transport protein B 5 157 9.9E-61 T 01-11-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 MLA2C4_03750 ec3a14ccab6714d637c938bf63695425 240 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 7.9E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_03750 ec3a14ccab6714d637c938bf63695425 240 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 7.9E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_03750 ec3a14ccab6714d637c938bf63695425 240 Gene3D G3DSA:3.40.50.300 2 193 8.6E-44 T 01-11-2018 MLA2C4_03750 ec3a14ccab6714d637c938bf63695425 240 SUPERFAMILY SSF52540 5 209 1.2E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09275 5c55051fb4b1e51353da78c6a90ee639 277 SUPERFAMILY SSF161098 12 277 8.32E-76 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_09275 5c55051fb4b1e51353da78c6a90ee639 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 263 4.4E-20 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_09275 5c55051fb4b1e51353da78c6a90ee639 277 Gene3D G3DSA:1.10.3720.10 8 269 2.7E-69 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_27965 1264c56d640e91d40931ddafaeeb423b 97 Pfam PF12823 Domain of unknown function (DUF3817) 7 93 8.3E-21 T 01-11-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MLA2C4_27965 1264c56d640e91d40931ddafaeeb423b 97 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 10 92 1.4E-26 T 01-11-2018 IPR023845 Domain of unknown function DUF3817, transmembrane MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 Pfam PF00072 Response regulator receiver domain 5 109 8.8E-8 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 SMART SM00850 136 237 1.6E-31 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 Gene3D G3DSA:2.40.50.1020 130 238 7.0E-15 T 01-11-2018 MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 Pfam PF04397 LytTr DNA-binding domain 138 236 6.1E-28 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 Gene3D G3DSA:3.40.50.2300 1 129 1.3E-12 T 01-11-2018 MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 SUPERFAMILY SSF52172 1 169 1.27E-15 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_28070 7d909fd23a24abe13992d27bff8ad603 238 SMART SM00448 1 112 9.0E-4 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 Gene3D G3DSA:1.10.357.10 1 188 1.8E-37 T 01-11-2018 MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 50 3.5E-12 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 5.8E-9 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 5.8E-9 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 Pfam PF16925 Bacterial transcriptional repressor C-terminal 77 187 1.1E-8 T 01-11-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 SUPERFAMILY SSF48498 76 188 4.71E-15 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_16810 dd732f409db159b9b2ec00556fd723fa 188 SUPERFAMILY SSF46689 3 69 9.23E-16 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 Gene3D G3DSA:3.30.870.10 133 333 1.1E-46 T 01-11-2018 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 36 509 1.0E-146 T 01-11-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 Gene3D G3DSA:3.30.870.10 336 485 1.4E-27 T 01-11-2018 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 Pfam PF13091 PLD-like domain 351 476 7.6E-26 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 Pfam PF13091 PLD-like domain 155 298 3.2E-15 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 SUPERFAMILY SSF56024 100 338 3.77E-51 T 01-11-2018 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 Hamap MF_01916 Cardiolipin synthase. 33 509 41.093 T 01-11-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 SUPERFAMILY SSF56024 290 493 1.91E-44 T 01-11-2018 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 SMART SM00155 238 265 3.2E-6 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 SMART SM00155 422 449 2.4E-7 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_03290 ec7589c5e23b5089dee9be0000a9657f 509 Pfam PF13396 Phospholipase_D-nuclease N-terminal 39 81 2.0E-9 T 01-11-2018 IPR027379 Cardiolipin synthase N-terminal MLA2C4_25695 a22775f6af0f6f498d69d1fafcaf5242 187 Pfam PF13302 Acetyltransferase (GNAT) domain 40 160 4.9E-23 T 01-11-2018 IPR000182 GNAT domain MLA2C4_25695 a22775f6af0f6f498d69d1fafcaf5242 187 SUPERFAMILY SSF55729 10 186 5.21E-38 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_25695 a22775f6af0f6f498d69d1fafcaf5242 187 Gene3D G3DSA:3.40.630.30 7 186 3.2E-39 T 01-11-2018 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 Pfam PF00365 Phosphofructokinase 3 275 4.0E-115 T 01-11-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 3.9E-90 T 01-11-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 Gene3D G3DSA:3.40.50.460 142 251 3.6E-121 T 01-11-2018 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 PIRSF PIRSF000532 1 319 6.9E-125 T 01-11-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 50.11 T 01-11-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 SUPERFAMILY SSF53784 1 316 9.68E-121 T 01-11-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 1.3E-141 T 01-11-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 Gene3D G3DSA:3.40.50.450 3 278 3.6E-121 T 01-11-2018 MLA2C4_23895 698695ed5de9dc49310e5edf791eec95 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 01-11-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 01-11-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 SMART SM00845 325 472 6.0E-77 T 01-11-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 Pfam PF02637 GatB domain 325 472 6.6E-56 T 01-11-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 472 9.3E-182 T 01-11-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 SUPERFAMILY SSF55931 4 293 4.9E-122 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 Gene3D G3DSA:1.10.150.380 297 410 5.0E-37 T 01-11-2018 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 Gene3D G3DSA:1.10.10.410 412 475 6.1E-26 T 01-11-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 SUPERFAMILY SSF89095 294 400 1.31E-35 T 01-11-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 Pfam PF02934 GatB/GatE catalytic domain 6 285 3.5E-112 T 01-11-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 MLA2C4_01915 5f61453e25d33d7c400b53d51b4144cf 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 473 39.118 T 01-11-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 SUPERFAMILY SSF47781 252 345 1.59E-12 T 01-11-2018 IPR010994 RuvA domain 2-like MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 137 1.4E-26 T 01-11-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 Gene3D G3DSA:1.20.1260.110 144 289 1.4E-45 T 01-11-2018 IPR038331 DisA, linker domain superfamily MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 Gene3D G3DSA:3.40.1700.10 8 143 2.3E-56 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 6 354 45.01 T 01-11-2018 IPR023763 DNA integrity scanning protein, DisA MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 SUPERFAMILY SSF143597 17 143 2.88E-28 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 281 8.5E-51 T 01-11-2018 IPR018906 DNA integrity scanning, DisA, linker region MLA2C4_00535 d7fbb8169a18f7926db37af301ac7380 357 Gene3D G3DSA:1.10.150.20 290 351 3.1E-21 T 01-11-2018 MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 195 1.2E-8 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 Gene3D G3DSA:1.10.150.240 21 98 1.1E-115 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 201 1.0E-7 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 2 254 5.0E-117 T 01-11-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 1.2E-16 T 01-11-2018 MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 SUPERFAMILY SSF56784 2 255 1.24E-64 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 Gene3D G3DSA:3.40.50.1000 3 253 1.1E-115 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_07035 a70f0551dd945c4af7ba8656dd526657 264 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 264 131.792 T 01-11-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 MLA2C4_16100 a97f7c5b3dbd4f64e8e58f92cb947402 488 Gene3D G3DSA:1.20.1740.10 20 483 5.3E-61 T 01-11-2018 MLA2C4_16100 a97f7c5b3dbd4f64e8e58f92cb947402 488 PIRSF PIRSF006060 2 481 1.2E-84 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_16100 a97f7c5b3dbd4f64e8e58f92cb947402 488 Pfam PF00324 Amino acid permease 29 478 1.0E-135 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_16100 a97f7c5b3dbd4f64e8e58f92cb947402 488 ProSitePatterns PS00218 Amino acid permeases signature. 54 85 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.739 T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 TIGRFAM TIGR00077 lspA: signal peptidase II 2 151 3.9E-47 T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 1.3E-18 T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.3E-18 T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 1.3E-18 T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 Pfam PF01252 Signal peptidase (SPase) II 6 144 6.8E-40 T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_20350 13002576d84af35a182e2e058892bc9d 152 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 01-11-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MLA2C4_13850 10ede112a0287e0a993d7fa3e283e194 256 Pfam PF00005 ABC transporter 24 170 2.8E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_13850 10ede112a0287e0a993d7fa3e283e194 256 SMART SM00382 31 226 1.9E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13850 10ede112a0287e0a993d7fa3e283e194 256 Gene3D G3DSA:3.40.50.300 1 245 6.7E-65 T 01-11-2018 MLA2C4_13850 10ede112a0287e0a993d7fa3e283e194 256 SUPERFAMILY SSF52540 3 224 7.1E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08440 0dcf244896fd3d0ebd1d2912365fe8a3 194 Pfam PF02698 DUF218 domain 43 183 1.3E-30 T 01-11-2018 IPR003848 Domain of unknown function DUF218 MLA2C4_15360 4fb55318406c5af6f27b1f28731203a0 159 PIRSF PIRSF021441 1 159 2.6E-55 T 01-11-2018 IPR031306 CcdC protein MLA2C4_15360 4fb55318406c5af6f27b1f28731203a0 159 Pfam PF07301 Protein of unknown function (DUF1453) 7 150 1.2E-44 T 01-11-2018 IPR009916 Protein of unknown function DUF1453 MLA2C4_10690 66b6f213c5b736c6f617b6fda32d05ad 141 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 2 125 1.1E-48 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_10690 66b6f213c5b736c6f617b6fda32d05ad 141 PIRSF PIRSF021377 1 140 4.3E-53 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_10690 66b6f213c5b736c6f617b6fda32d05ad 141 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 30 116 1.4E-26 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 PIRSF PIRSF002599 1 66 2.3E-24 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 SUPERFAMILY SSF50249 1 64 7.46E-26 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 5.1E-30 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 PRINTS PR00050 Cold shock protein signature 24 33 1.8E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 PRINTS PR00050 Cold shock protein signature 39 57 1.8E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 01-11-2018 IPR019844 Cold-shock conserved site MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 SMART SM00357 3 66 1.1E-30 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_18375 dabdaa7ae00e3d09b6afd78923bfde9a 66 Gene3D G3DSA:2.40.50.140 1 66 6.8E-31 T 01-11-2018 MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 SUPERFAMILY SSF52821 250 354 8.91E-11 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 Gene3D G3DSA:3.40.250.10 266 368 5.6E-16 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 Pfam PF00581 Rhodanese-like domain 276 338 8.1E-5 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 Pfam PF00581 Rhodanese-like domain 383 466 4.3E-14 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 Pfam PF00753 Metallo-beta-lactamase superfamily 13 176 1.3E-8 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 SUPERFAMILY SSF56281 5 262 7.14E-47 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 SUPERFAMILY SSF52821 368 473 6.42E-30 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 Gene3D G3DSA:3.40.250.10 379 476 1.8E-25 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 SMART SM00849 12 199 5.2E-21 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 Gene3D G3DSA:3.60.15.10 1 262 9.0E-79 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 SMART SM00450 371 470 9.3E-21 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_13420 c565384b31e15d14532e65c065f51b43 478 SMART SM00450 272 359 9.3 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_12055 184d18b09ebef7d50a04eae6d91c3079 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 2.8E-24 T 01-11-2018 IPR019618 Spore germination protein GerPA/GerPF MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 Gene3D G3DSA:3.40.630.10 11 352 5.6E-75 T 01-11-2018 MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 Pfam PF01546 Peptidase family M20/M25/M40 66 363 2.9E-21 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 Gene3D G3DSA:3.30.70.360 166 277 5.6E-75 T 01-11-2018 MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 SUPERFAMILY SSF53187 5 369 1.85E-61 T 01-11-2018 MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 Pfam PF07687 Peptidase dimerisation domain 174 259 4.2E-7 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 PIRSF PIRSF005962 1 371 3.0E-86 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 352 5.7E-81 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_02015 7eb02493d3729226b6b7ab98a3b53558 371 SUPERFAMILY SSF55031 170 277 3.29E-18 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_02140 9016ece58ee2e954966658625f8bedee 433 SUPERFAMILY SSF103473 10 431 1.31E-81 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_02140 9016ece58ee2e954966658625f8bedee 433 Gene3D G3DSA:1.20.1250.20 21 433 3.6E-78 T 01-11-2018 MLA2C4_02140 9016ece58ee2e954966658625f8bedee 433 Pfam PF07690 Major Facilitator Superfamily 29 305 5.1E-35 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_11240 96943fb3b3d66c96a03ef526b6d9bd35 280 Gene3D G3DSA:3.30.1180.10 153 279 5.2E-37 T 01-11-2018 MLA2C4_11240 96943fb3b3d66c96a03ef526b6d9bd35 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 8.5E-104 T 01-11-2018 IPR003797 DegV MLA2C4_11240 96943fb3b3d66c96a03ef526b6d9bd35 280 SUPERFAMILY SSF82549 1 279 2.49E-94 T 01-11-2018 MLA2C4_11240 96943fb3b3d66c96a03ef526b6d9bd35 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 7.3E-94 T 01-11-2018 IPR003797 DegV MLA2C4_11240 96943fb3b3d66c96a03ef526b6d9bd35 280 Gene3D G3DSA:3.40.50.10170 1 152 5.7E-54 T 01-11-2018 MLA2C4_12185 879570ceefe52eadc61c01211b41b70f 400 Pfam PF07690 Major Facilitator Superfamily 216 392 2.2E-17 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_12185 879570ceefe52eadc61c01211b41b70f 400 Gene3D G3DSA:1.20.1250.20 1 396 1.7E-46 T 01-11-2018 MLA2C4_12185 879570ceefe52eadc61c01211b41b70f 400 SUPERFAMILY SSF103473 8 393 1.44E-48 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 SUPERFAMILY SSF55846 235 393 1.01E-43 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 Pfam PF00395 S-layer homology domain 402 441 3.1E-5 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 Pfam PF00395 S-layer homology domain 457 499 3.5E-8 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 Pfam PF00395 S-layer homology domain 520 560 8.4E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 252 375 6.7E-21 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 Gene3D G3DSA:3.40.80.10 228 391 1.6E-46 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_19120 c6b46f5e40a253155b97335eedd2af4e 575 SMART SM00644 242 387 6.5E-22 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 SUPERFAMILY SSF58104 489 726 3.14E-6 T 01-11-2018 MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 230 1.4E-6 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 665 692 5.8E-8 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 693 720 3.7E-8 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 645 671 3.0E-4 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 623 650 9.8E-6 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 567 594 1.8E-4 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 595 622 2.0E-8 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 Pfam PF12698 ABC-2 family transporter protein 24 170 7.1E-15 T 01-11-2018 MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 Pfam PF12698 ABC-2 family transporter protein 766 953 3.2E-16 T 01-11-2018 MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 760 963 1.1E-66 T 01-11-2018 IPR017501 Phage infection protein, YhgE, C-terminal MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.1E-60 T 01-11-2018 IPR017500 Phage infection protein, YhgE, N-terminal MLA2C4_05755 1a4bc129c81b9ce5468a536f0fa9d775 978 SUPERFAMILY SSF58104 243 466 5.75E-5 T 01-11-2018 MLA2C4_10365 8973e163f1eb48146ccc1906103e3d96 200 Pfam PF09335 SNARE associated Golgi protein 30 156 1.3E-24 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_06450 f70759e021a9c902841962db448768c8 303 Pfam PF00892 EamA-like transporter family 149 282 1.8E-15 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_06450 f70759e021a9c902841962db448768c8 303 Pfam PF00892 EamA-like transporter family 13 136 3.2E-14 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_06450 f70759e021a9c902841962db448768c8 303 SUPERFAMILY SSF103481 185 286 6.15E-13 T 01-11-2018 MLA2C4_06450 f70759e021a9c902841962db448768c8 303 SUPERFAMILY SSF103481 38 140 1.24E-14 T 01-11-2018 MLA2C4_00190 cc3dc1a467041822cb80c43a13df9561 327 SUPERFAMILY SSF52540 11 203 3.86E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00190 cc3dc1a467041822cb80c43a13df9561 327 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 198 3.8E-62 T 01-11-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_00190 cc3dc1a467041822cb80c43a13df9561 327 Gene3D G3DSA:3.40.50.300 10 169 6.3E-52 T 01-11-2018 MLA2C4_00190 cc3dc1a467041822cb80c43a13df9561 327 Pfam PF13177 DNA polymerase III, delta subunit 13 170 2.1E-56 T 01-11-2018 MLA2C4_04710 0a2e7d8bf0cf5643f529b9fdff6b9d2e 186 Pfam PF08006 Protein of unknown function (DUF1700) 1 184 4.1E-65 T 01-11-2018 IPR012963 Protein of unknown function DUF1700 MLA2C4_17790 4b726e5e9f5245a706e99263d27f8856 279 SUPERFAMILY SSF56112 13 226 1.41E-21 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_17790 4b726e5e9f5245a706e99263d27f8856 279 Gene3D G3DSA:3.90.1200.10 90 265 3.6E-12 T 01-11-2018 MLA2C4_17790 4b726e5e9f5245a706e99263d27f8856 279 Pfam PF01636 Phosphotransferase enzyme family 163 224 3.1E-5 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 Gene3D G3DSA:3.40.190.10 37 252 9.7E-71 T 01-11-2018 MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 SMART SM00062 37 255 1.1E-65 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 253 1.6E-68 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 SMART SM00079 37 254 9.7E-4 T 01-11-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 Gene3D G3DSA:3.40.190.10 121 217 9.7E-71 T 01-11-2018 MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 SUPERFAMILY SSF53850 1 255 1.05E-69 T 01-11-2018 MLA2C4_02160 a0294a8e3a1246b92ed719097246433e 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 01-11-2018 IPR018313 Solute-binding protein family 3, conserved site MLA2C4_02595 2fe92c2b00f46f272a2e282bee683fd4 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 1.2E-124 T 01-11-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MLA2C4_02595 2fe92c2b00f46f272a2e282bee683fd4 309 SUPERFAMILY SSF56601 6 309 1.63E-113 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_02595 2fe92c2b00f46f272a2e282bee683fd4 309 Gene3D G3DSA:3.40.710.10 3 309 1.5E-110 T 01-11-2018 MLA2C4_02595 2fe92c2b00f46f272a2e282bee683fd4 309 Pfam PF04960 Glutaminase 23 309 1.5E-111 T 01-11-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MLA2C4_02595 2fe92c2b00f46f272a2e282bee683fd4 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 47.133 T 01-11-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MLA2C4_21735 46f5cac284f992459e817cbed611be33 135 PIRSF PIRSF021328 1 135 2.6E-45 T 01-11-2018 IPR016787 Uncharacterised conserved protein UCP021328 MLA2C4_21735 46f5cac284f992459e817cbed611be33 135 Pfam PF11208 Protein of unknown function (DUF2992) 3 135 9.8E-38 T 01-11-2018 IPR016787 Uncharacterised conserved protein UCP021328 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 01-11-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 Gene3D G3DSA:3.30.360.10 155 318 1.3E-87 T 01-11-2018 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 SUPERFAMILY SSF51735 3 176 1.7E-13 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 Pfam PF00742 Homoserine dehydrogenase 158 334 2.1E-50 T 01-11-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 Gene3D G3DSA:3.40.50.720 6 326 1.3E-87 T 01-11-2018 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 PIRSF PIRSF036497 1 342 3.1E-104 T 01-11-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 SUPERFAMILY SSF55347 155 317 8.5E-42 T 01-11-2018 MLA2C4_13875 5ea812d548734b02b5d8784f533f565d 347 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 146 1.1E-6 T 01-11-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 Pfam PF05977 Transmembrane secretion effector 12 350 9.7E-26 T 01-11-2018 IPR010290 Transmembrane secretion effector MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 80 98 4.3E-12 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 253 270 4.3E-12 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 169 186 4.3E-12 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 17 39 4.3E-12 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 PRINTS PR01988 Putative bacilysin exporter bacE signature 142 163 4.3E-12 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 Gene3D G3DSA:1.20.1250.20 10 392 2.7E-29 T 01-11-2018 MLA2C4_08485 f58b4bfab1bb37252358255cc9790d62 404 SUPERFAMILY SSF103473 12 396 1.44E-38 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 SUPERFAMILY SSF52172 1 130 1.99E-32 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 2.4E-15 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 SMART SM00421 149 206 2.7E-17 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 SUPERFAMILY SSF46894 149 207 6.46E-16 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.9E-10 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.9E-10 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.9E-10 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 Gene3D G3DSA:3.40.50.12740 3 211 1.8E-59 T 01-11-2018 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 Pfam PF00072 Response regulator receiver domain 5 116 2.5E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09080 263c2f62378f63ddb91b55ef256391e9 212 SMART SM00448 3 115 4.0E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03090 0a4e8e001e338b39c87cd9d0335a485e 308 SUPERFAMILY SSF103481 43 148 9.94E-9 T 01-11-2018 MLA2C4_03090 0a4e8e001e338b39c87cd9d0335a485e 308 SUPERFAMILY SSF103481 193 297 9.16E-15 T 01-11-2018 MLA2C4_03090 0a4e8e001e338b39c87cd9d0335a485e 308 Pfam PF00892 EamA-like transporter family 159 293 7.2E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_03090 0a4e8e001e338b39c87cd9d0335a485e 308 Pfam PF00892 EamA-like transporter family 7 146 1.3E-16 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 PIRSF PIRSF003128 1 571 9.1E-185 T 01-11-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 SUPERFAMILY SSF52540 4 521 4.59E-28 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 Gene3D G3DSA:3.40.50.300 1 270 7.0E-49 T 01-11-2018 MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 521 3.6E-14 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 1.1E-188 T 01-11-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 Gene3D G3DSA:3.40.50.300 302 567 1.5E-49 T 01-11-2018 MLA2C4_21835 edbe5917bb4ca54a957cb6ea2c125531 579 SUPERFAMILY SSF52540 2 218 2.23E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12785 071f17964d385e5da901580389eeba55 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_12785 071f17964d385e5da901580389eeba55 156 SUPERFAMILY SSF46785 6 147 2.98E-25 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12785 071f17964d385e5da901580389eeba55 156 Gene3D G3DSA:1.10.10.10 1 145 1.6E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_12785 071f17964d385e5da901580389eeba55 156 Pfam PF01047 MarR family 36 91 6.2E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_12785 071f17964d385e5da901580389eeba55 156 SMART SM00347 26 129 4.0E-15 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_10480 fbfbdb90f41aab29716b60544f307cc4 246 SUPERFAMILY SSF55166 91 236 1.33E-36 T 01-11-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MLA2C4_10480 fbfbdb90f41aab29716b60544f307cc4 246 Gene3D G3DSA:3.30.1380.10 36 246 9.6E-76 T 01-11-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MLA2C4_10480 fbfbdb90f41aab29716b60544f307cc4 246 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 99 227 1.5E-45 T 01-11-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MLA2C4_19930 4c75c647d9016c3331619cb84082a880 93 Pfam PF04456 Protein of unknown function (DUF503) 3 87 1.3E-29 T 01-11-2018 IPR007546 Protein of unknown function DUF503 MLA2C4_19930 4c75c647d9016c3331619cb84082a880 93 SUPERFAMILY SSF103007 1 93 6.93E-32 T 01-11-2018 IPR036746 TT1725-like superfamily MLA2C4_19930 4c75c647d9016c3331619cb84082a880 93 Gene3D G3DSA:3.30.70.1120 1 93 9.7E-24 T 01-11-2018 IPR036746 TT1725-like superfamily MLA2C4_06180 d7d017a84d7d93ddaa2e63f373df0f06 310 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 72.942 T 01-11-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_06180 d7d017a84d7d93ddaa2e63f373df0f06 310 Gene3D G3DSA:3.40.47.10 1 310 3.2E-134 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_06180 d7d017a84d7d93ddaa2e63f373df0f06 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 308 1.8E-36 T 01-11-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_06180 d7d017a84d7d93ddaa2e63f373df0f06 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 9.5E-32 T 01-11-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_06180 d7d017a84d7d93ddaa2e63f373df0f06 310 SUPERFAMILY SSF53901 3 308 2.89E-72 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_06180 d7d017a84d7d93ddaa2e63f373df0f06 310 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 308 1.5E-133 T 01-11-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_07200 20fcd134a09aac65dcd35f09c4d34d4d 300 Gene3D G3DSA:3.40.50.300 3 242 1.4E-62 T 01-11-2018 MLA2C4_07200 20fcd134a09aac65dcd35f09c4d34d4d 300 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_07200 20fcd134a09aac65dcd35f09c4d34d4d 300 SUPERFAMILY SSF52540 2 236 2.05E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07200 20fcd134a09aac65dcd35f09c4d34d4d 300 Pfam PF00005 ABC transporter 22 163 9.9E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_07200 20fcd134a09aac65dcd35f09c4d34d4d 300 SMART SM00382 30 212 1.1E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 SUPERFAMILY SSF47973 1 149 5.89E-61 T 01-11-2018 IPR036823 Ribosomal protein S7 domain superfamily MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 PIRSF PIRSF002122 5 156 1.5E-59 T 01-11-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.7E-70 T 01-11-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 Gene3D G3DSA:1.10.455.10 2 156 4.3E-64 T 01-11-2018 IPR036823 Ribosomal protein S7 domain superfamily MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.0E-66 T 01-11-2018 IPR023798 Ribosomal protein S7 domain MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 01-11-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00650 bd1f6f5df6c6c43bbfb25063d7a22d1b 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.472 T 01-11-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_03075 db9ab1909c26f4d37fb2d61cd88bcedc 448 PIRSF PIRSF005348 13 448 9.6E-171 T 01-11-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 MLA2C4_03075 db9ab1909c26f4d37fb2d61cd88bcedc 448 Pfam PF03390 2-hydroxycarboxylate transporter family 32 442 3.8E-161 T 01-11-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 4.3E-5 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 4.3E-5 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.3E-5 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 Gene3D G3DSA:1.10.1660.10 1 129 5.5E-24 T 01-11-2018 MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.3E-15 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 SUPERFAMILY SSF46955 2 108 4.03E-21 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_17660 c0c095a58c7b95ee2fbb5a61b7c63b9e 135 SMART SM00422 2 70 1.1E-19 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_08805 7de38765f385c62df7b30fc9971928f8 266 TIGRFAM TIGR01076 sortase_fam: sortase 98 231 1.0E-52 T 01-11-2018 IPR005754 Sortase family MLA2C4_08805 7de38765f385c62df7b30fc9971928f8 266 SUPERFAMILY SSF63817 60 227 5.89E-47 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_08805 7de38765f385c62df7b30fc9971928f8 266 Pfam PF04203 Sortase family 100 225 1.4E-25 T 01-11-2018 IPR005754 Sortase family MLA2C4_08805 7de38765f385c62df7b30fc9971928f8 266 Gene3D G3DSA:2.40.260.10 29 239 1.7E-66 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_13545 b0490192b7654840567a00f3469ce62f 245 Pfam PF01048 Phosphorylase superfamily 12 234 5.2E-38 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MLA2C4_13545 b0490192b7654840567a00f3469ce62f 245 SUPERFAMILY SSF53167 10 235 1.44E-48 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MLA2C4_13545 b0490192b7654840567a00f3469ce62f 245 Gene3D G3DSA:3.40.50.1580 2 242 3.4E-44 T 01-11-2018 MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 Gene3D G3DSA:3.40.50.300 1 285 1.5E-135 T 01-11-2018 MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 Pfam PF06418 CTP synthase N-terminus 3 267 8.1E-131 T 01-11-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 4.4E-264 T 01-11-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 Pfam PF00117 Glutamine amidotransferase class-I 302 526 3.1E-60 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 SUPERFAMILY SSF52540 1 269 2.8E-127 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 Gene3D G3DSA:3.40.50.880 286 535 1.7E-102 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 SUPERFAMILY SSF52317 289 533 1.01E-83 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_27640 5b6ee9c45a7c3d4fd5d29c4eb8fa478b 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 52.993 T 01-11-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MLA2C4_07840 e0a854800d4c670794c67adbf414c00f 291 SMART SM00422 8 77 2.6E-10 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_07840 e0a854800d4c670794c67adbf414c00f 291 Pfam PF13411 MerR HTH family regulatory protein 8 75 1.3E-14 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_07840 e0a854800d4c670794c67adbf414c00f 291 SUPERFAMILY SSF46955 8 85 3.16E-15 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_07840 e0a854800d4c670794c67adbf414c00f 291 Gene3D G3DSA:1.10.1660.10 3 75 1.4E-22 T 01-11-2018 MLA2C4_11420 29bc0ba27970f8faa295c09c406a6312 606 SUPERFAMILY SSF52540 276 447 1.88E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11420 29bc0ba27970f8faa295c09c406a6312 606 Gene3D G3DSA:3.40.50.300 264 447 5.7E-16 T 01-11-2018 MLA2C4_11420 29bc0ba27970f8faa295c09c406a6312 606 Pfam PF07728 AAA domain (dynein-related subfamily) 282 434 1.3E-7 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MLA2C4_25295 651f9d238434aca278ad61c90476ecf3 260 Gene3D G3DSA:3.60.160.10 1 248 2.2E-104 T 01-11-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily MLA2C4_25295 651f9d238434aca278ad61c90476ecf3 260 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 4.3E-70 T 01-11-2018 IPR002838 Mitochondrial biogenesis protein AIM24 MLA2C4_25295 651f9d238434aca278ad61c90476ecf3 260 SUPERFAMILY SSF51219 6 243 4.45E-84 T 01-11-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily MLA2C4_25295 651f9d238434aca278ad61c90476ecf3 260 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 7 232 1.8E-34 T 01-11-2018 IPR002838 Mitochondrial biogenesis protein AIM24 MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 Gene3D G3DSA:2.60.40.10 34 172 3.9E-24 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 Pfam PF00746 LPXTG cell wall anchor motif 529 559 3.3E-4 T 01-11-2018 IPR019948 Gram-positive LPXTG cell wall anchor MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 SUPERFAMILY SSF49478 428 489 2.0E-6 T 01-11-2018 MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 529 559 1.5E-6 T 01-11-2018 MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 Gene3D G3DSA:2.60.40.10 173 278 4.1E-41 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 Gene3D G3DSA:2.60.40.10 420 525 1.9E-25 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 Gene3D G3DSA:2.60.40.740 279 419 4.7E-36 T 01-11-2018 MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 278 398 2.8E-22 T 01-11-2018 IPR026466 Fimbrial isopeptide formation D2 domain MLA2C4_13575 e04ed3887731b9dc803f6e85a938824f 563 SUPERFAMILY SSF49478 181 246 1.22E-8 T 01-11-2018 MLA2C4_10625 d015b0b38666385378032379560fee93 161 SUPERFAMILY SSF55729 1 149 8.35E-35 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10625 d015b0b38666385378032379560fee93 161 Pfam PF00583 Acetyltransferase (GNAT) family 41 137 8.4E-19 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10625 d015b0b38666385378032379560fee93 161 Gene3D G3DSA:3.40.630.30 1 160 9.2E-46 T 01-11-2018 MLA2C4_04435 8fe3f8dee80319284c684682f9377543 259 Pfam PF11155 Domain of unknown function (DUF2935) 8 114 3.9E-21 T 01-11-2018 IPR021328 Protein of unknown function DUF2935 MLA2C4_04435 8fe3f8dee80319284c684682f9377543 259 Pfam PF11155 Domain of unknown function (DUF2935) 127 245 5.3E-27 T 01-11-2018 IPR021328 Protein of unknown function DUF2935 MLA2C4_04435 8fe3f8dee80319284c684682f9377543 259 SUPERFAMILY SSF158430 4 123 8.37E-36 T 01-11-2018 MLA2C4_04435 8fe3f8dee80319284c684682f9377543 259 SUPERFAMILY SSF158430 125 258 5.89E-42 T 01-11-2018 MLA2C4_04435 8fe3f8dee80319284c684682f9377543 259 Gene3D G3DSA:1.20.1260.120 1 259 2.4E-104 T 01-11-2018 MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 6.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 6.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 6.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 SUPERFAMILY SSF46785 5 135 5.0E-30 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 Gene3D G3DSA:1.10.10.10 1 136 4.2E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 Pfam PF01047 MarR family 36 85 3.2E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_26260 25b913750c5f77c8c8ff1bc0f87a10f3 136 SMART SM00347 28 125 1.5E-18 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_13760 6e64b0e242f9c3e1f887925e53705bfb 308 Gene3D G3DSA:3.90.180.10 1 94 3.3E-13 T 01-11-2018 MLA2C4_13760 6e64b0e242f9c3e1f887925e53705bfb 308 SUPERFAMILY SSF51735 116 253 8.21E-15 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_13760 6e64b0e242f9c3e1f887925e53705bfb 308 Gene3D G3DSA:3.90.180.10 99 293 1.1E-19 T 01-11-2018 MLA2C4_13760 6e64b0e242f9c3e1f887925e53705bfb 308 SUPERFAMILY SSF50129 6 146 3.35E-22 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_13760 6e64b0e242f9c3e1f887925e53705bfb 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 1.4E-5 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_13760 6e64b0e242f9c3e1f887925e53705bfb 308 Gene3D G3DSA:3.40.50.720 125 250 1.1E-19 T 01-11-2018 MLA2C4_23185 81f7a7ac818e368266e6096997a5ec60 248 SUPERFAMILY SSF51261 102 244 1.2E-21 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_23185 81f7a7ac818e368266e6096997a5ec60 248 Gene3D G3DSA:2.70.70.10 117 246 2.1E-22 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_23185 81f7a7ac818e368266e6096997a5ec60 248 Pfam PF01551 Peptidase family M23 148 241 1.5E-21 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_13535 45e3dee604f33e335531fdb6b1dad691 202 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 30 188 3.0E-22 T 01-11-2018 IPR005249 Conserved hypothetical protein CHP00488 MLA2C4_13535 45e3dee604f33e335531fdb6b1dad691 202 Pfam PF01966 HD domain 31 144 8.2E-14 T 01-11-2018 IPR006674 HD domain MLA2C4_13535 45e3dee604f33e335531fdb6b1dad691 202 SUPERFAMILY SSF109604 8 157 7.01E-23 T 01-11-2018 MLA2C4_13535 45e3dee604f33e335531fdb6b1dad691 202 Gene3D G3DSA:1.10.3210.10 15 199 1.2E-39 T 01-11-2018 MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 Gene3D G3DSA:3.40.50.1100 22 434 5.5E-202 T 01-11-2018 MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 Gene3D G3DSA:3.40.50.1100 114 236 5.5E-202 T 01-11-2018 MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 10 434 3.4E-227 T 01-11-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 446 262.088 T 01-11-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 SUPERFAMILY SSF53686 49 432 6.86E-59 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 106 120 - T 01-11-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MLA2C4_09045 c4ecaf2b1eb20ac7ba6e4d8138e42cb8 446 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 395 6.4E-57 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_03990 1b1a776e4eb2b3ae9b6020f5d627ea62 555 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 554 32.388 T 01-11-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MLA2C4_03990 1b1a776e4eb2b3ae9b6020f5d627ea62 555 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 3 554 4.8E-202 T 01-11-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MLA2C4_03990 1b1a776e4eb2b3ae9b6020f5d627ea62 555 PIRSF PIRSF001294 1 555 1.1E-233 T 01-11-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MLA2C4_03990 1b1a776e4eb2b3ae9b6020f5d627ea62 555 Pfam PF03814 Potassium-transporting ATPase A subunit 8 552 2.3E-227 T 01-11-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MLA2C4_09180 43157b04323eb5bf50b804ba6871c8ee 327 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 12 319 4.7E-104 T 01-11-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MLA2C4_09180 43157b04323eb5bf50b804ba6871c8ee 327 PIRSF PIRSF001555 1 327 7.5E-162 T 01-11-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MLA2C4_09180 43157b04323eb5bf50b804ba6871c8ee 327 SUPERFAMILY SSF55681 8 320 7.69E-88 T 01-11-2018 MLA2C4_09180 43157b04323eb5bf50b804ba6871c8ee 327 Gene3D G3DSA:3.30.930.10 5 323 3.0E-142 T 01-11-2018 MLA2C4_09180 43157b04323eb5bf50b804ba6871c8ee 327 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 4 323 50.471 T 01-11-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MLA2C4_09180 43157b04323eb5bf50b804ba6871c8ee 327 Pfam PF03590 Aspartate-ammonia ligase 12 237 2.2E-106 T 01-11-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 Gene3D G3DSA:1.10.287.990 120 182 1.9E-24 T 01-11-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 103 183 3.7E-28 T 01-11-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 SUPERFAMILY SSF46609 99 183 1.31E-31 T 01-11-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 SUPERFAMILY SSF54719 182 296 3.14E-42 T 01-11-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 190 292 3.6E-36 T 01-11-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 259 266 - T 01-11-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 Gene3D G3DSA:2.40.500.20 183 302 1.7E-45 T 01-11-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 PRINTS PR01703 Manganese superoxide dismutase signature 106 117 2.0E-21 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 PRINTS PR01703 Manganese superoxide dismutase signature 257 269 2.0E-21 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 PRINTS PR01703 Manganese superoxide dismutase signature 219 227 2.0E-21 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 PRINTS PR01703 Manganese superoxide dismutase signature 166 179 2.0E-21 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_07740 7ddb2e635f3fc05f641993670de68f53 304 PRINTS PR01703 Manganese superoxide dismutase signature 127 140 2.0E-21 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_21555 85bf75d5fd16863f10c5f47a64108703 242 Gene3D G3DSA:3.40.50.300 2 221 1.4E-61 T 01-11-2018 MLA2C4_21555 85bf75d5fd16863f10c5f47a64108703 242 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 221 30.0 T 01-11-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MLA2C4_21555 85bf75d5fd16863f10c5f47a64108703 242 PIRSF PIRSF006755 1 230 1.6E-61 T 01-11-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MLA2C4_21555 85bf75d5fd16863f10c5f47a64108703 242 SUPERFAMILY SSF52540 1 206 2.58E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21555 85bf75d5fd16863f10c5f47a64108703 242 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 172 4.1E-52 T 01-11-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MLA2C4_21555 85bf75d5fd16863f10c5f47a64108703 242 Pfam PF13500 AAA domain 4 203 1.8E-45 T 01-11-2018 MLA2C4_21075 c34a38cb7df769ded5e9ab202f08b9b1 110 Gene3D G3DSA:1.10.10.10 1 110 9.5E-37 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21075 c34a38cb7df769ded5e9ab202f08b9b1 110 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 1.7E-23 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_21075 c34a38cb7df769ded5e9ab202f08b9b1 110 SUPERFAMILY SSF46785 11 105 1.34E-26 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 81 91 - T 01-11-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 1.8E-18 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.8E-18 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 1.8E-18 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 Gene3D G3DSA:3.40.50.40 209 322 2.9E-31 T 01-11-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 SMART SM00870 3 318 5.9E-143 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 Pfam PF00710 Asparaginase, N-terminal 3 191 2.7E-60 T 01-11-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 PIRSF PIRSF500176 1 324 1.8E-93 T 01-11-2018 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 SUPERFAMILY SSF53774 2 322 3.27E-103 T 01-11-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 01-11-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 Gene3D G3DSA:3.40.50.1170 1 208 1.5E-66 T 01-11-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MLA2C4_07875 9b6347777d67dc21c4acc3abfebea281 324 PIRSF PIRSF001220 1 324 5.2E-98 T 01-11-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 8.6E-16 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 SUPERFAMILY SSF55874 310 477 3.01E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 SMART SM00387 367 480 1.5E-34 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 SMART SM00388 254 321 5.3E-17 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 Gene3D G3DSA:1.10.287.130 250 320 3.5E-20 T 01-11-2018 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 478 1.5E-25 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 Gene3D G3DSA:3.30.565.10 326 478 4.0E-43 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 SMART SM00304 194 246 2.4E-13 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 7.4E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 7.4E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 7.4E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 477 7.4E-17 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 Pfam PF00672 HAMP domain 194 242 3.6E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 SUPERFAMILY SSF47384 241 321 3.73E-18 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 Gene3D G3DSA:1.20.1480.50 158 249 1.1E-16 T 01-11-2018 MLA2C4_24265 9948ec99f9c16a009306bfd4e2511b23 484 SUPERFAMILY SSF158472 194 245 1.57E-11 T 01-11-2018 MLA2C4_17755 24eb84260052f6282cbcc96c2c65f7f0 111 Pfam PF08858 IDEAL domain 74 100 2.5E-7 T 01-11-2018 IPR014957 IDEAL domain MLA2C4_17755 24eb84260052f6282cbcc96c2c65f7f0 111 Gene3D G3DSA:4.10.810.10 70 108 5.1E-6 T 01-11-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 MLA2C4_17755 24eb84260052f6282cbcc96c2c65f7f0 111 SMART SM00914 65 100 3.8E-8 T 01-11-2018 IPR014957 IDEAL domain MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 38.685 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 SUPERFAMILY SSF54782 219 302 8.89E-22 T 01-11-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 SUPERFAMILY SSF53850 2 217 1.17E-81 T 01-11-2018 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 8.4E-18 T 01-11-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 5.2E-49 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 5.2E-49 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 5.2E-49 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 5.2E-49 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 5.2E-49 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 PIRSF PIRSF001438 1 309 9.2E-121 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 Gene3D G3DSA:3.40.190.10 4 209 4.0E-84 T 01-11-2018 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 01-11-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 Gene3D G3DSA:3.40.190.10 101 201 4.0E-84 T 01-11-2018 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 3.7E-111 T 01-11-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 6.3E-79 T 01-11-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23270 46165dce5d02b266099e3f87325c9750 309 Gene3D G3DSA:3.30.160.40 220 303 9.4E-27 T 01-11-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_00245 ddfd6e0f194e009023e8b25216be93b6 287 PIRSF PIRSF011575 2 286 6.2E-110 T 01-11-2018 IPR008764 Peptidase U57, YabG MLA2C4_00245 ddfd6e0f194e009023e8b25216be93b6 287 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 282 1.5E-138 T 01-11-2018 IPR008764 Peptidase U57, YabG MLA2C4_00245 ddfd6e0f194e009023e8b25216be93b6 287 Pfam PF05582 YabG peptidase U57 5 281 7.2E-112 T 01-11-2018 IPR008764 Peptidase U57, YabG MLA2C4_00245 ddfd6e0f194e009023e8b25216be93b6 287 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 3 276 7.0E-160 T 01-11-2018 IPR008764 Peptidase U57, YabG MLA2C4_03370 e4f63718d835a109b86c5fa0b6651de5 323 Gene3D G3DSA:3.90.1200.10 122 316 2.3E-20 T 01-11-2018 MLA2C4_03370 e4f63718d835a109b86c5fa0b6651de5 323 SUPERFAMILY SSF56112 11 311 3.68E-46 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_03370 e4f63718d835a109b86c5fa0b6651de5 323 Pfam PF01636 Phosphotransferase enzyme family 31 257 7.6E-26 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_06345 756c00f102bc489aac5b609b36d73dc4 281 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 8 280 4.5E-111 T 01-11-2018 IPR008884 Macrocin-O-methyltransferase MLA2C4_06345 756c00f102bc489aac5b609b36d73dc4 281 SUPERFAMILY SSF53335 79 270 1.54E-8 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_27260 1328fdcee7b1e9bc86754b3ef22788f7 364 Pfam PF00534 Glycosyl transferases group 1 173 342 2.6E-28 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_27260 1328fdcee7b1e9bc86754b3ef22788f7 364 Gene3D G3DSA:3.40.50.2000 53 359 5.8E-44 T 01-11-2018 MLA2C4_27260 1328fdcee7b1e9bc86754b3ef22788f7 364 SUPERFAMILY SSF53756 50 362 5.38E-53 T 01-11-2018 MLA2C4_27260 1328fdcee7b1e9bc86754b3ef22788f7 364 Gene3D G3DSA:3.40.50.2000 166 348 5.8E-44 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 SUPERFAMILY SSF53067 197 368 1.46E-41 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 434 30.479 T 01-11-2018 IPR020823 Cell division protein FtsA MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Gene3D G3DSA:3.90.640.10 233 298 1.2E-107 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Gene3D G3DSA:3.30.420.40 10 354 1.2E-107 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 1.1E-120 T 01-11-2018 IPR020823 Cell division protein FtsA MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Gene3D G3DSA:3.30.420.40 195 349 1.2E-107 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Gene3D G3DSA:3.30.1490.110 83 167 1.2E-107 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 370 435 1.3E-8 T 01-11-2018 IPR021873 Cell division protein FtsA, C-terminal MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 PIRSF PIRSF003101 1 434 1.3E-144 T 01-11-2018 IPR020823 Cell division protein FtsA MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Pfam PF14450 Cell division protein FtsA 205 366 2.9E-22 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Pfam PF14450 Cell division protein FtsA 9 188 4.5E-10 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 SUPERFAMILY SSF53067 6 192 8.43E-57 T 01-11-2018 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 Pfam PF02491 SHS2 domain inserted in FTSA 83 160 5.9E-24 T 01-11-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 206 219 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MLA2C4_20420 3ab0c2b0326a4ef15ae452d8251f2a77 435 SMART SM00842 7 194 2.2E-92 T 01-11-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MLA2C4_18380 830e9005a415da4c69b848c1bc583694 299 Gene3D G3DSA:2.130.10.10 6 139 6.0E-9 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MLA2C4_18380 830e9005a415da4c69b848c1bc583694 299 SUPERFAMILY SSF69322 52 291 8.89E-7 T 01-11-2018 MLA2C4_18380 830e9005a415da4c69b848c1bc583694 299 SUPERFAMILY SSF110296 7 120 6.28E-16 T 01-11-2018 MLA2C4_23130 90cd42d0228173113d42f0d7b1436b6a 640 PIRSF PIRSF018968 1 640 5.7E-125 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_23130 90cd42d0228173113d42f0d7b1436b6a 640 Pfam PF02687 FtsX-like permease family 86 181 3.8E-8 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 SUPERFAMILY SSF50249 3 65 7.42E-16 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 383 456 9.4E-13 T 01-11-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 Pfam PF01938 TRAM domain 12 64 5.1E-10 T 01-11-2018 IPR002792 TRAM domain MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 Gene3D G3DSA:2.40.50.140 3 85 1.9E-20 T 01-11-2018 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 01-11-2018 IPR030391 RNA methyltransferase TrmA, conserved site MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 22 450 5.0E-188 T 01-11-2018 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 Gene3D G3DSA:3.40.1350.30 134 289 1.6E-127 T 01-11-2018 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 Gene3D G3DSA:3.40.50.150 87 452 1.6E-127 T 01-11-2018 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 Pfam PF02475 Met-10+ like-protein 211 360 8.4E-9 T 01-11-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 SUPERFAMILY SSF53335 74 455 9.62E-90 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_01970 9d19b771523fe8965b92e035b0b3b198 458 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 01-11-2018 IPR030390 RNA methyltransferase TrmA, active site MLA2C4_06980 e6e0c01bb1ee344115f12ab65f996d9e 150 TIGRFAM TIGR02719 repress_PhaQ: poly-beta-hydroxybutyrate-responsive repressor 4 141 8.1E-86 T 01-11-2018 IPR014091 Transcriptional repressor poly-beta-hydroxybutyrate-responsive MLA2C4_06980 e6e0c01bb1ee344115f12ab65f996d9e 150 Pfam PF03551 Transcriptional regulator PadR-like family 32 103 2.8E-18 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_06980 e6e0c01bb1ee344115f12ab65f996d9e 150 SUPERFAMILY SSF46785 15 121 8.44E-26 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_06980 e6e0c01bb1ee344115f12ab65f996d9e 150 Gene3D G3DSA:1.10.10.10 15 127 1.1E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21415 21495ff2380602ecc63c892070e724f0 215 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 206 1.1E-80 T 01-11-2018 IPR014196 Stage II sporulation protein M MLA2C4_21415 21495ff2380602ecc63c892070e724f0 215 PIRSF PIRSF038973 2 213 3.3E-70 T 01-11-2018 IPR014196 Stage II sporulation protein M MLA2C4_21415 21495ff2380602ecc63c892070e724f0 215 Pfam PF01944 Stage II sporulation protein M 26 202 1.6E-21 T 01-11-2018 IPR002798 Stage II sporulation protein M-like MLA2C4_28235 14896acd676ac8013633a11cf5990904 407 SUPERFAMILY SSF55781 153 298 1.45E-9 T 01-11-2018 MLA2C4_28235 14896acd676ac8013633a11cf5990904 407 Gene3D G3DSA:3.30.450.40 143 300 3.7E-8 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_11125 1b0e288a27ffb749d3174cdbbab2cda7 157 Pfam PF01980 Uncharacterised protein family UPF0066 23 130 7.3E-31 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain MLA2C4_11125 1b0e288a27ffb749d3174cdbbab2cda7 157 Gene3D G3DSA:2.40.30.70 2 132 4.1E-33 T 01-11-2018 IPR036414 YaeB, N-terminal domain superfamily MLA2C4_11125 1b0e288a27ffb749d3174cdbbab2cda7 157 SUPERFAMILY SSF118196 1 151 4.18E-46 T 01-11-2018 IPR036413 YaeB-like superfamily MLA2C4_11125 1b0e288a27ffb749d3174cdbbab2cda7 157 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 130 3.4E-27 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain MLA2C4_16425 d9ba7fdf1c00005c81862bc0b5244221 363 Gene3D G3DSA:1.20.1740.10 5 360 9.2E-15 T 01-11-2018 MLA2C4_16425 d9ba7fdf1c00005c81862bc0b5244221 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 360 5.9E-85 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_16425 d9ba7fdf1c00005c81862bc0b5244221 363 Pfam PF03845 Spore germination protein 8 329 5.1E-115 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 Gene3D G3DSA:3.30.565.10 312 462 4.1E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 Gene3D G3DSA:1.20.1480.50 153 241 1.8E-9 T 01-11-2018 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 SUPERFAMILY SSF47384 234 310 1.24E-14 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 462 9.2E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 SMART SM00304 187 239 2.3E-7 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 SMART SM00387 356 464 7.0E-18 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 Gene3D G3DSA:1.10.287.130 242 311 3.3E-15 T 01-11-2018 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 SUPERFAMILY SSF158472 188 235 2.09E-7 T 01-11-2018 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 Pfam PF00672 HAMP domain 188 234 1.2E-7 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 309 2.5E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 SMART SM00388 247 312 6.6E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_27200 c5ad32db0e11e3a3c7c756554e221130 476 SUPERFAMILY SSF55874 316 460 3.01E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_25555 5933daad4ee208a2608fa0a57c5ea869 207 Gene3D G3DSA:3.30.420.10 2 197 3.3E-39 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_25555 5933daad4ee208a2608fa0a57c5ea869 207 Pfam PF00929 Exonuclease 8 173 2.1E-22 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_25555 5933daad4ee208a2608fa0a57c5ea869 207 SUPERFAMILY SSF53098 4 178 4.26E-30 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_25555 5933daad4ee208a2608fa0a57c5ea869 207 SMART SM00479 5 182 1.6E-31 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_03360 0466c0476ee1af201abf86e81ef999a1 199 Pfam PF12389 Camelysin metallo-endopeptidase 2 198 6.3E-89 T 01-11-2018 IPR022121 Peptidase M73, camelysin MLA2C4_03360 0466c0476ee1af201abf86e81ef999a1 199 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 44 3.6E-13 T 01-11-2018 IPR023833 Signal peptide, camelysin MLA2C4_20690 8881d79f56838da7916ec71330a279b1 89 SUPERFAMILY SSF158504 4 86 9.55E-35 T 01-11-2018 IPR023324 BH2638-like superfamily MLA2C4_20690 8881d79f56838da7916ec71330a279b1 89 Gene3D G3DSA:1.10.220.80 12 89 2.1E-30 T 01-11-2018 IPR023324 BH2638-like superfamily MLA2C4_20690 8881d79f56838da7916ec71330a279b1 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 86 3.0E-41 T 01-11-2018 IPR007920 Protein of unknown function UPF0223 MLA2C4_20690 8881d79f56838da7916ec71330a279b1 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 86 3.7E-38 T 01-11-2018 IPR007920 Protein of unknown function UPF0223 MLA2C4_20690 8881d79f56838da7916ec71330a279b1 89 Hamap MF_01041 UPF0223 protein . 1 88 27.212 T 01-11-2018 IPR007920 Protein of unknown function UPF0223 MLA2C4_20690 8881d79f56838da7916ec71330a279b1 89 PIRSF PIRSF037260 1 89 3.7E-40 T 01-11-2018 IPR007920 Protein of unknown function UPF0223 MLA2C4_22370 57beeaea6042ecec0a352efd5cbe3ccd 137 SUPERFAMILY SSF46785 5 133 1.63E-32 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22370 57beeaea6042ecec0a352efd5cbe3ccd 137 Pfam PF01475 Ferric uptake regulator family 13 129 5.9E-28 T 01-11-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MLA2C4_22370 57beeaea6042ecec0a352efd5cbe3ccd 137 Gene3D G3DSA:3.30.1490.190 87 137 5.3E-14 T 01-11-2018 MLA2C4_22370 57beeaea6042ecec0a352efd5cbe3ccd 137 Gene3D G3DSA:1.10.10.10 1 83 3.4E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 330 1.1E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 SMART SM00387 376 487 5.5E-37 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 Gene3D G3DSA:1.10.287.130 270 327 4.1E-14 T 01-11-2018 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 SUPERFAMILY SSF47384 249 332 4.71E-16 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 Gene3D G3DSA:3.30.565.10 335 487 1.9E-46 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 SUPERFAMILY SSF158472 212 260 9.94E-7 T 01-11-2018 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 SMART SM00388 265 331 1.9E-16 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 SMART SM00304 212 264 1.2E-4 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 4.2E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 4.2E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 4.2E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 441 4.2E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 SUPERFAMILY SSF55874 321 486 4.58E-46 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 486 4.0E-26 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03105 9368632cfb3cb9b48e92169b8b1d36fa 487 Gene3D G3DSA:1.20.1480.50 178 269 1.1E-11 T 01-11-2018 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 01-11-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 SMART SM01209 101 293 8.2E-135 T 01-11-2018 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Gene3D G3DSA:3.30.1490.20 119 188 2.9E-29 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 SUPERFAMILY SSF52440 1 101 4.03E-35 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Gene3D G3DSA:3.90.600.10 325 423 2.0E-33 T 01-11-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 9.2E-172 T 01-11-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 SUPERFAMILY SSF51246 324 416 3.92E-29 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Gene3D G3DSA:3.40.50.20 2 93 8.2E-37 T 01-11-2018 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.1E-35 T 01-11-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 414 1.8E-27 T 01-11-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Gene3D G3DSA:3.30.470.20 189 324 8.5E-57 T 01-11-2018 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 6.0E-85 T 01-11-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 SMART SM01210 325 416 9.6E-46 T 01-11-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 42.688 T 01-11-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MLA2C4_01800 0f58dd1cdbf6da69462ae1f8706fb4fa 423 SUPERFAMILY SSF56059 102 314 6.01E-64 T 01-11-2018 MLA2C4_23520 51f015971666a71330126e59b8d69e42 258 Gene3D G3DSA:3.90.226.10 1 258 7.4E-94 T 01-11-2018 MLA2C4_23520 51f015971666a71330126e59b8d69e42 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MLA2C4_23520 51f015971666a71330126e59b8d69e42 258 SUPERFAMILY SSF52096 2 258 1.63E-83 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_23520 51f015971666a71330126e59b8d69e42 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 1.7E-65 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 Pfam PF08281 Sigma-70, region 4 115 167 1.9E-17 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 SUPERFAMILY SSF88946 7 108 6.67E-18 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 SUPERFAMILY SSF88659 108 172 3.55E-17 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 Gene3D G3DSA:1.10.10.10 110 178 5.6E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 Gene3D G3DSA:1.10.1740.10 7 89 2.1E-14 T 01-11-2018 MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 171 2.9E-24 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_24210 86468f92f01c64bb0225e8198b3ba03b 181 Pfam PF04542 Sigma-70 region 2 29 92 4.2E-9 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_26465 ecd87496d1f3426ef80a11395f8e50cc 193 Pfam PF00484 Carbonic anhydrase 32 177 3.7E-12 T 01-11-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MLA2C4_26465 ecd87496d1f3426ef80a11395f8e50cc 193 Gene3D G3DSA:3.40.1050.10 1 183 5.4E-43 T 01-11-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MLA2C4_26465 ecd87496d1f3426ef80a11395f8e50cc 193 SMART SM00947 25 182 6.0E-26 T 01-11-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MLA2C4_26465 ecd87496d1f3426ef80a11395f8e50cc 193 SUPERFAMILY SSF53056 3 181 4.06E-35 T 01-11-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 SUPERFAMILY SSF63520 189 286 1.44E-15 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Pfam PF05043 Mga helix-turn-helix domain 89 169 6.1E-11 T 01-11-2018 IPR007737 Mga helix-turn-helix domain MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 SUPERFAMILY SSF55804 505 645 9.55E-34 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Pfam PF00874 PRD domain 211 286 5.0E-15 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Pfam PF00874 PRD domain 313 401 1.6E-20 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 SUPERFAMILY SSF63520 303 403 6.54E-23 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Pfam PF08279 HTH domain 7 64 5.4E-12 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Gene3D G3DSA:1.10.1790.10 191 290 6.5E-13 T 01-11-2018 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 508 644 4.6E-32 T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Gene3D G3DSA:3.40.930.10 505 645 4.0E-32 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Gene3D G3DSA:1.10.1790.10 304 403 8.9E-21 T 01-11-2018 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Gene3D G3DSA:1.10.10.10 1 157 6.0E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 SUPERFAMILY SSF52794 411 495 1.31E-6 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_04345 75e10ac7856600e71cc308381eaae9c2 646 Gene3D G3DSA:3.40.50.2300 412 502 1.4E-8 T 01-11-2018 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 SUPERFAMILY SSF51419 14 250 1.06E-62 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 Gene3D G3DSA:2.40.37.10 11 373 5.8E-135 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 Gene3D G3DSA:3.20.20.10 16 229 5.8E-135 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 SMART SM01005 249 374 3.2E-67 T 01-11-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 33 49 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 69 87 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 356 369 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 207 234 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 164 175 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 282 297 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 265 280 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 129 141 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 PRINTS PR00992 Alanine racemase signature 302 319 1.9E-64 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 Pfam PF00842 Alanine racemase, C-terminal domain 249 372 5.1E-41 T 01-11-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 Pfam PF01168 Alanine racemase, N-terminal domain 14 234 8.1E-65 T 01-11-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 01-11-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 SUPERFAMILY SSF50621 244 385 2.58E-49 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 Hamap MF_01201 Alanine racemase. 7 374 34.139 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_01415 358f8af1b51592a07fdef7ab7186c698 389 TIGRFAM TIGR00492 alr: alanine racemase 8 374 1.9E-116 T 01-11-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 SUPERFAMILY SSF52540 670 917 1.02E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 SMART SM00490 780 863 1.5E-24 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 SMART SM00487 447 637 1.2E-30 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 Pfam PF00176 SNF2 family N-terminal domain 470 735 9.1E-58 T 01-11-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 Gene3D G3DSA:3.40.50.10810 430 664 3.2E-71 T 01-11-2018 IPR038718 SNF2-like, N-terminal domain superfamily MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 Pfam PF00271 Helicase conserved C-terminal domain 752 863 1.1E-22 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 Pfam PF12419 SNF2 Helicase protein 270 398 7.0E-34 T 01-11-2018 IPR022138 Helicase SWF/SNF-related MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 Gene3D G3DSA:3.40.50.300 675 877 9.9E-90 T 01-11-2018 MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 Gene3D G3DSA:1.20.120.850 689 912 9.9E-90 T 01-11-2018 MLA2C4_27130 b82981f01ca1f0bf7a513aad03dd63dd 918 SUPERFAMILY SSF52540 425 665 2.06E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01100 8ad364c6b19c37dfd279be3e14cd3e3b 529 PIRSF PIRSF002741 1 524 1.8E-110 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_01100 8ad364c6b19c37dfd279be3e14cd3e3b 529 Gene3D G3DSA:3.40.190.10 46 516 2.1E-147 T 01-11-2018 MLA2C4_01100 8ad364c6b19c37dfd279be3e14cd3e3b 529 Gene3D G3DSA:3.10.105.10 288 503 2.1E-147 T 01-11-2018 MLA2C4_01100 8ad364c6b19c37dfd279be3e14cd3e3b 529 SUPERFAMILY SSF53850 28 517 6.88E-124 T 01-11-2018 MLA2C4_01100 8ad364c6b19c37dfd279be3e14cd3e3b 529 Gene3D G3DSA:3.90.76.10 66 188 2.1E-147 T 01-11-2018 MLA2C4_01100 8ad364c6b19c37dfd279be3e14cd3e3b 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 452 1.1E-81 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_21395 e83c2adf0e5cb17fe49e08820bc91314 247 Pfam PF13115 YtkA-like 30 113 4.0E-15 T 01-11-2018 IPR032693 YtkA-like domain MLA2C4_21395 e83c2adf0e5cb17fe49e08820bc91314 247 Pfam PF13115 YtkA-like 159 230 1.1E-10 T 01-11-2018 IPR032693 YtkA-like domain MLA2C4_27210 c96c89489ef931b84a1730b0b5bd36df 314 Gene3D G3DSA:2.60.120.10 1 225 1.0E-94 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_27210 c96c89489ef931b84a1730b0b5bd36df 314 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 99 312 2.0E-52 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MLA2C4_27210 c96c89489ef931b84a1730b0b5bd36df 314 SUPERFAMILY SSF51182 1 313 5.14E-106 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_27210 c96c89489ef931b84a1730b0b5bd36df 314 Pfam PF01238 Phosphomannose isomerase type I 8 195 1.0E-41 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MLA2C4_27210 c96c89489ef931b84a1730b0b5bd36df 314 PIRSF PIRSF036894 2 314 6.4E-132 T 01-11-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 MLA2C4_27210 c96c89489ef931b84a1730b0b5bd36df 314 Gene3D G3DSA:2.60.120.10 227 314 6.9E-25 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_18910 a4841ca766218cb3d98bfa39bef32791 273 SMART SM00332 3 271 0.0016 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_18910 a4841ca766218cb3d98bfa39bef32791 273 Pfam PF13672 Protein phosphatase 2C 20 227 3.1E-15 T 01-11-2018 MLA2C4_18910 a4841ca766218cb3d98bfa39bef32791 273 Gene3D G3DSA:3.60.40.10 5 273 9.1E-22 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_18910 a4841ca766218cb3d98bfa39bef32791 273 SUPERFAMILY SSF81606 8 273 1.29E-19 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_24090 522ec98021ef0574fa4266966c4d0b01 137 SUPERFAMILY SSF55811 3 122 7.85E-16 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_24090 522ec98021ef0574fa4266966c4d0b01 137 Pfam PF00293 NUDIX domain 8 123 3.1E-9 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_24090 522ec98021ef0574fa4266966c4d0b01 137 Gene3D G3DSA:3.90.79.10 3 137 3.2E-19 T 01-11-2018 MLA2C4_24090 522ec98021ef0574fa4266966c4d0b01 137 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 27 53 - T 01-11-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 Pfam PF01037 Lrp/AsnC ligand binding domain 78 147 3.0E-20 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 SUPERFAMILY SSF54909 69 156 2.41E-18 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 Gene3D G3DSA:1.10.10.10 2 61 1.2E-18 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.8E-13 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.8E-13 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.8E-13 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 1.2E-13 T 01-11-2018 MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 SUPERFAMILY SSF46785 8 69 1.06E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 SMART SM00344 9 118 4.2E-39 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_04540 4c56114c00ef8c51d7f9ee1f9ce703ac 164 Gene3D G3DSA:3.30.70.920 62 152 7.6E-24 T 01-11-2018 MLA2C4_16275 965607df0a2b4f36aeb8b7bcb908f41b 194 SUPERFAMILY SSF53254 1 180 2.1E-27 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_16275 965607df0a2b4f36aeb8b7bcb908f41b 194 Gene3D G3DSA:3.40.50.1240 1 185 4.0E-27 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_16275 965607df0a2b4f36aeb8b7bcb908f41b 194 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 161 2.2E-24 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_22745 7b162827b8602e6c66c04cee7584c3fe 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 124 3.2E-12 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_22745 7b162827b8602e6c66c04cee7584c3fe 285 SUPERFAMILY SSF54593 2 156 2.42E-36 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_22745 7b162827b8602e6c66c04cee7584c3fe 285 SUPERFAMILY SSF54593 167 279 3.58E-21 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_22745 7b162827b8602e6c66c04cee7584c3fe 285 Gene3D G3DSA:3.10.180.10 11 146 6.0E-25 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_22745 7b162827b8602e6c66c04cee7584c3fe 285 Gene3D G3DSA:3.10.180.10 166 284 1.6E-19 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_26075 04da45c67ba274bdfee2574409b14e76 252 Pfam PF11495 Archaeal transcriptional regulator TrmB 102 222 7.8E-6 T 01-11-2018 IPR021586 Transcription regulator TrmB, C-terminal MLA2C4_26075 04da45c67ba274bdfee2574409b14e76 252 Gene3D G3DSA:1.10.10.10 1 95 1.4E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26075 04da45c67ba274bdfee2574409b14e76 252 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 70 8.1E-21 T 01-11-2018 IPR002831 Transcription regulator TrmB, N-terminal MLA2C4_26075 04da45c67ba274bdfee2574409b14e76 252 SUPERFAMILY SSF46785 1 87 2.59E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12345 b69c78c895de4e60ad2c762715334ab2 200 Gene3D G3DSA:1.10.3800.10 31 171 6.1E-84 T 01-11-2018 MLA2C4_12345 b69c78c895de4e60ad2c762715334ab2 200 Gene3D G3DSA:3.20.170.10 5 195 6.1E-84 T 01-11-2018 MLA2C4_12345 b69c78c895de4e60ad2c762715334ab2 200 Pfam PF10386 Protein of unknown function (DUF2441) 31 171 1.3E-64 T 01-11-2018 IPR018840 Protein of unknown function DUF2441 MLA2C4_12345 b69c78c895de4e60ad2c762715334ab2 200 SUPERFAMILY SSF56399 3 195 2.04E-60 T 01-11-2018 MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 SUPERFAMILY SSF47413 1 59 8.06E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 SUPERFAMILY SSF53822 60 329 2.78E-67 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 Gene3D G3DSA:3.40.50.2300 62 302 3.3E-62 T 01-11-2018 MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.8E-18 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 306 4.1E-34 T 01-11-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 SMART SM00354 1 71 7.0E-29 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 Gene3D G3DSA:3.40.50.2300 159 288 3.3E-62 T 01-11-2018 MLA2C4_13360 3fefa152369ab9ec098899ff1cc0c0bd 329 Gene3D G3DSA:1.10.260.40 3 59 2.2E-21 T 01-11-2018 MLA2C4_15185 5d448444f7a22344a6d7ba8211590d13 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 283 1.1E-82 T 01-11-2018 IPR003797 DegV MLA2C4_15185 5d448444f7a22344a6d7ba8211590d13 286 Gene3D G3DSA:3.40.50.10170 1 154 2.0E-44 T 01-11-2018 MLA2C4_15185 5d448444f7a22344a6d7ba8211590d13 286 SUPERFAMILY SSF82549 1 284 3.92E-89 T 01-11-2018 MLA2C4_15185 5d448444f7a22344a6d7ba8211590d13 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 281 2.1E-95 T 01-11-2018 IPR003797 DegV MLA2C4_15185 5d448444f7a22344a6d7ba8211590d13 286 Gene3D G3DSA:3.30.1180.10 157 285 4.9E-48 T 01-11-2018 MLA2C4_21740 7d791e9d8e148eeb5b02a57692b06846 154 Pfam PF00293 NUDIX domain 20 145 1.9E-23 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_21740 7d791e9d8e148eeb5b02a57692b06846 154 Gene3D G3DSA:3.90.79.10 1 151 8.7E-39 T 01-11-2018 MLA2C4_21740 7d791e9d8e148eeb5b02a57692b06846 154 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_21740 7d791e9d8e148eeb5b02a57692b06846 154 SUPERFAMILY SSF55811 1 148 4.6E-33 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_21740 7d791e9d8e148eeb5b02a57692b06846 154 PRINTS PR00502 NUDIX hydrolase family signature 58 73 2.3E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_21740 7d791e9d8e148eeb5b02a57692b06846 154 PRINTS PR00502 NUDIX hydrolase family signature 44 58 2.3E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_11850 f55e9d1626cab69748e1deb18982cc8c 1139 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 224 561 5.2E-84 T 01-11-2018 IPR010090 Phage tail tape measure protein MLA2C4_11850 f55e9d1626cab69748e1deb18982cc8c 1139 SUPERFAMILY SSF57997 82 197 2.29E-6 T 01-11-2018 MLA2C4_11850 f55e9d1626cab69748e1deb18982cc8c 1139 Pfam PF10145 Phage-related minor tail protein 263 461 3.8E-47 T 01-11-2018 IPR010090 Phage tail tape measure protein MLA2C4_11850 f55e9d1626cab69748e1deb18982cc8c 1139 Gene3D G3DSA:1.20.5.340 101 196 2.1E-6 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 Gene3D G3DSA:3.50.50.100 1 355 2.3E-78 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 3.8E-7 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 3.8E-7 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.8E-7 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 289 1.2E-39 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 SUPERFAMILY SSF51905 1 308 2.09E-29 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.8E-9 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.8E-9 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.8E-9 T 01-11-2018 MLA2C4_25715 38bcea8ba97c7601409f29f91fcbf77f 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 7.8E-9 T 01-11-2018 MLA2C4_17780 a48c6f8a50f0feaa74c88edd1274e652 274 Gene3D G3DSA:3.60.15.10 43 273 3.8E-13 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_17780 a48c6f8a50f0feaa74c88edd1274e652 274 Pfam PF00753 Metallo-beta-lactamase superfamily 76 201 1.6E-5 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_17780 a48c6f8a50f0feaa74c88edd1274e652 274 SMART SM00849 75 239 2.0E-8 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_17780 a48c6f8a50f0feaa74c88edd1274e652 274 SUPERFAMILY SSF56281 56 243 1.62E-26 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 SMART SM00347 29 129 3.2E-19 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 Pfam PF01047 MarR family 39 93 3.7E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 9.0E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 9.0E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 9.0E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 9.0E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 Gene3D G3DSA:1.10.10.10 1 143 2.9E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21585 5196212888a209ddfff73806a7ee5303 148 SUPERFAMILY SSF46785 28 143 5.17E-27 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 SMART SM01060 8 391 3.7E-278 T 01-11-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 01-11-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PRINTS PR00067 Catalase signature 124 142 1.9E-76 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PRINTS PR00067 Catalase signature 321 347 1.9E-76 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PRINTS PR00067 Catalase signature 84 102 1.9E-76 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PRINTS PR00067 Catalase signature 21 44 1.9E-76 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PRINTS PR00067 Catalase signature 105 122 1.9E-76 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PRINTS PR00067 Catalase signature 289 316 1.9E-76 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 Pfam PF00199 Catalase 8 387 1.0E-190 T 01-11-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 Pfam PF06628 Catalase-related immune-responsive 413 475 7.6E-18 T 01-11-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 Gene3D G3DSA:2.40.180.10 1 487 2.7E-228 T 01-11-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 01-11-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 SUPERFAMILY SSF56634 3 483 1.96E-210 T 01-11-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_06075 82b890edfea470e5e4af1fb7842270ec 488 PIRSF PIRSF038928 1 481 3.5E-200 T 01-11-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 Pfam PF00206 Lyase 44 307 4.3E-42 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 Pfam PF14698 Argininosuccinate lyase C-terminal 374 446 1.2E-12 T 01-11-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 Gene3D G3DSA:1.10.275.10 42 237 1.9E-128 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 TIGRFAM TIGR00838 argH: argininosuccinate lyase 31 471 6.5E-99 T 01-11-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 Gene3D G3DSA:1.10.40.30 370 448 1.9E-128 T 01-11-2018 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 SUPERFAMILY SSF48557 35 470 2.36E-95 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 5.4E-18 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 5.4E-18 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 5.4E-18 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 5.4E-18 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 Gene3D G3DSA:1.20.200.10 127 466 1.9E-128 T 01-11-2018 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 3.0E-27 T 01-11-2018 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 3.0E-27 T 01-11-2018 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 3.0E-27 T 01-11-2018 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 3.0E-27 T 01-11-2018 MLA2C4_18425 5c3e6b63aab8414fa6a164718d27688b 502 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 3.0E-27 T 01-11-2018 MLA2C4_07520 edaa0305c86f0e2d6c7792a133e28b16 197 Gene3D G3DSA:3.40.50.300 1 197 3.5E-85 T 01-11-2018 MLA2C4_07520 edaa0305c86f0e2d6c7792a133e28b16 197 SUPERFAMILY SSF52540 23 193 2.38E-41 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07520 edaa0305c86f0e2d6c7792a133e28b16 197 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 23 195 38.88 T 01-11-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MLA2C4_07520 edaa0305c86f0e2d6c7792a133e28b16 197 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 191 1.1E-86 T 01-11-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MLA2C4_07520 edaa0305c86f0e2d6c7792a133e28b16 197 Pfam PF01583 Adenylylsulphate kinase 25 177 2.3E-74 T 01-11-2018 MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 Gene3D G3DSA:3.40.190.290 91 283 4.7E-37 T 01-11-2018 MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 Gene3D G3DSA:1.10.10.10 1 90 6.0E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.1E-18 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 Pfam PF03466 LysR substrate binding domain 88 281 7.9E-40 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 SUPERFAMILY SSF53850 88 282 4.93E-35 T 01-11-2018 MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 SUPERFAMILY SSF46785 1 110 1.36E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18170 d4b2d54c6a968d58d04fe4fc3070a21f 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_19990 b68d996f6ce6a17c030a278924b05ae3 185 Gene3D G3DSA:1.10.132.20 12 182 1.8E-71 T 01-11-2018 MLA2C4_19990 b68d996f6ce6a17c030a278924b05ae3 185 Pfam PF01765 Ribosome recycling factor 21 183 3.3E-65 T 01-11-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MLA2C4_19990 b68d996f6ce6a17c030a278924b05ae3 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.2E-77 T 01-11-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MLA2C4_19990 b68d996f6ce6a17c030a278924b05ae3 185 Gene3D G3DSA:3.30.1360.40 31 105 1.8E-71 T 01-11-2018 MLA2C4_19990 b68d996f6ce6a17c030a278924b05ae3 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.238 T 01-11-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MLA2C4_19990 b68d996f6ce6a17c030a278924b05ae3 185 SUPERFAMILY SSF55194 5 184 2.35E-71 T 01-11-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 Gene3D G3DSA:3.40.47.10 126 388 2.7E-166 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 Pfam PF00108 Thiolase, N-terminal domain 4 261 1.3E-88 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 Gene3D G3DSA:3.40.47.10 5 274 2.7E-166 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 7.2E-47 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 9.7E-147 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 SUPERFAMILY SSF53901 3 268 1.4E-84 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 PIRSF PIRSF000429 1 391 1.9E-132 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 SUPERFAMILY SSF53901 269 389 1.28E-40 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_21040 74bf9b49aae539138374bd86cb6f7a4f 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 01-11-2018 IPR020610 Thiolase, active site GO:0016747 MLA2C4_12620 7a1471645c1a21b188d8dfb450a7f799 401 Pfam PF06013 Proteins of 100 residues with WXG 3 88 3.1E-13 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_12620 7a1471645c1a21b188d8dfb450a7f799 401 PIRSF PIRSF038601 1 401 1.1E-231 T 01-11-2018 IPR024696 Uncharacterised conserved protein, UCP038601 MLA2C4_12620 7a1471645c1a21b188d8dfb450a7f799 401 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 90 1.8E-21 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_12620 7a1471645c1a21b188d8dfb450a7f799 401 SUPERFAMILY SSF140453 3 93 4.45E-13 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_12620 7a1471645c1a21b188d8dfb450a7f799 401 Gene3D G3DSA:1.10.287.850 1 94 4.7E-28 T 01-11-2018 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 SUPERFAMILY SSF55021 260 346 6.87E-14 T 01-11-2018 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 SUPERFAMILY SSF53633 3 246 1.7E-68 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 Pfam PF00696 Amino acid kinase family 2 235 2.2E-47 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 Gene3D G3DSA:3.40.1160.10 1 254 7.3E-85 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 PIRSF PIRSF000726 1 67 2.3E-9 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 PIRSF PIRSF000726 61 409 1.9E-95 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 59 401 2.1E-96 T 01-11-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 SUPERFAMILY SSF55021 335 404 3.44E-17 T 01-11-2018 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 Pfam PF13840 ACT domain 336 398 8.4E-22 T 01-11-2018 IPR027795 CASTOR, ACT domain MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 Gene3D G3DSA:3.30.2130.10 255 409 8.2E-37 T 01-11-2018 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 6.6E-139 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_19870 6225c1227f3db4a28becd7c93dffab75 410 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 01-11-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 Gene3D G3DSA:3.40.1190.20 2 293 1.4E-90 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 PRINTS PR00990 Ribokinase signature 33 52 6.9E-33 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 PRINTS PR00990 Ribokinase signature 172 187 6.9E-33 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 PRINTS PR00990 Ribokinase signature 104 117 6.9E-33 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 PRINTS PR00990 Ribokinase signature 209 220 6.9E-33 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 PRINTS PR00990 Ribokinase signature 6 27 6.9E-33 T 01-11-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 291 7.0E-100 T 01-11-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 SUPERFAMILY SSF53613 4 292 1.17E-76 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 Pfam PF00294 pfkB family carbohydrate kinase 1 286 3.5E-69 T 01-11-2018 IPR011611 Carbohydrate kinase PfkB MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 01-11-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MLA2C4_03510 9724d79e07c184e833eca4b9e887b620 298 Hamap MF_01987 Ribokinase [rbsK]. 2 293 24.785 T 01-11-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MLA2C4_08650 29d46e25c5965645cd89497c7a035168 111 Pfam PF13107 Protein of unknown function (DUF3964) 2 108 2.3E-57 T 01-11-2018 IPR025082 Protein of unknown function DUF3964 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 316 1.9E-158 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 146 2.2E-65 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 SUPERFAMILY SSF52096 5 313 2.49E-103 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 132 148 7.3E-47 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 167 180 7.3E-47 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 86 97 7.3E-47 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 195 204 7.3E-47 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 151 164 7.3E-47 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 111 129 7.3E-47 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 3 314 49.622 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_23900 4155ab7de8aa97adca81258e8cddc761 324 Gene3D G3DSA:3.90.226.10 1 315 8.0E-123 T 01-11-2018 MLA2C4_21335 b75c5167a71c267291e12729a9356ad1 139 SUPERFAMILY SSF46785 6 78 1.31E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21335 b75c5167a71c267291e12729a9356ad1 139 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 4.6E-16 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_21335 b75c5167a71c267291e12729a9356ad1 139 Gene3D G3DSA:1.10.10.10 9 133 8.6E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21335 b75c5167a71c267291e12729a9356ad1 139 SMART SM00345 17 76 9.1E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 Pfam PF00344 SecY translocase 68 414 4.4E-110 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PIRSF PIRSF004557 1 434 2.4E-124 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 Gene3D G3DSA:1.10.3370.10 1 426 5.0E-155 T 01-11-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 1.5E-96 T 01-11-2018 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 3.8E-143 T 01-11-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 28.525 T 01-11-2018 IPR026593 Protein translocase subunit SecY MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 SUPERFAMILY SSF103491 1 421 1.28E-124 T 01-11-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_14515 5b5a8e42e42c9cff774020cfe30705a1 434 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 01-11-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_16690 fef8a5cca665e4bef259f4a99ce4fbb5 302 SUPERFAMILY SSF47240 3 296 2.77E-69 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_16690 fef8a5cca665e4bef259f4a99ce4fbb5 302 Pfam PF03405 Fatty acid desaturase 10 293 4.4E-49 T 01-11-2018 IPR005067 Fatty acid desaturase, type 2 GO:0006631|GO:0045300|GO:0055114 MLA2C4_16690 fef8a5cca665e4bef259f4a99ce4fbb5 302 Gene3D G3DSA:1.10.620.20 1 268 1.6E-82 T 01-11-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-19 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 Gene3D G3DSA:3.40.50.2300 2 123 1.1E-28 T 01-11-2018 MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 SMART SM00862 150 225 1.2E-21 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 Gene3D G3DSA:1.10.10.10 125 227 1.3E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 SUPERFAMILY SSF52172 1 125 7.26E-34 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 SMART SM00448 2 112 1.9E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 SUPERFAMILY SSF46894 128 226 3.97E-26 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_23145 7bd2b5913adc7ec262a30d81c1bd554e 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 1.2E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09410 f65097210152b4f35e4d8fb8e58c050d 178 SUPERFAMILY SSF55068 4 166 5.1E-71 T 01-11-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_09410 f65097210152b4f35e4d8fb8e58c050d 178 Gene3D G3DSA:3.30.1060.10 1 166 2.5E-65 T 01-11-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_09410 f65097210152b4f35e4d8fb8e58c050d 178 Pfam PF01625 Peptide methionine sulfoxide reductase 9 159 4.4E-60 T 01-11-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_09410 f65097210152b4f35e4d8fb8e58c050d 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 165 36.539 T 01-11-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_09410 f65097210152b4f35e4d8fb8e58c050d 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 158 7.8E-63 T 01-11-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MLA2C4_06900 9dceafb7505164c81e0ce7549ec7afc2 371 SUPERFAMILY SSF46689 259 335 2.87E-5 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_06900 9dceafb7505164c81e0ce7549ec7afc2 371 Pfam PF13556 PucR C-terminal helix-turn-helix domain 301 358 2.7E-19 T 01-11-2018 IPR025736 PucR C-terminal helix-turn-helix domain MLA2C4_06900 9dceafb7505164c81e0ce7549ec7afc2 371 Gene3D G3DSA:1.10.10.2840 242 363 7.1E-21 T 01-11-2018 MLA2C4_06900 9dceafb7505164c81e0ce7549ec7afc2 371 Pfam PF05651 Putative sugar diacid recognition 5 135 6.6E-49 T 01-11-2018 IPR008599 Putative sugar diacid recognition MLA2C4_09850 1a1e1eb922e2bc224cf6d5894b693707 107 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 101 2.7E-18 T 01-11-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MLA2C4_09850 1a1e1eb922e2bc224cf6d5894b693707 107 SUPERFAMILY SSF69118 11 103 9.5E-26 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_09850 1a1e1eb922e2bc224cf6d5894b693707 107 Gene3D G3DSA:1.20.1290.10 5 107 6.1E-29 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_08290 8ec347353b9bf305db235a73c97e34a6 412 SUPERFAMILY SSF52440 165 277 1.7E-6 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_08290 8ec347353b9bf305db235a73c97e34a6 412 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 19 405 1.2E-67 T 01-11-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MLA2C4_08290 8ec347353b9bf305db235a73c97e34a6 412 SUPERFAMILY SSF56059 3 403 5.65E-42 T 01-11-2018 MLA2C4_08290 8ec347353b9bf305db235a73c97e34a6 412 Gene3D G3DSA:3.30.1490.330 291 357 2.5E-8 T 01-11-2018 MLA2C4_23170 65e6247d9676c5236b8a8603944bdd40 102 SUPERFAMILY SSF141091 1 101 9.94E-39 T 01-11-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23170 65e6247d9676c5236b8a8603944bdd40 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 7.4E-40 T 01-11-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23170 65e6247d9676c5236b8a8603944bdd40 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.476 T 01-11-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23170 65e6247d9676c5236b8a8603944bdd40 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.6E-40 T 01-11-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23170 65e6247d9676c5236b8a8603944bdd40 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 01-11-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_23665 0015350430c9d142b74f50e3dfb2b701 89 Hamap MF_02013 Cell division protein ZapA [zapA]. 3 87 28.685 T 01-11-2018 IPR023688 Cell division protein ZapA, firmicutes GO:0051301 MLA2C4_23665 0015350430c9d142b74f50e3dfb2b701 89 SUPERFAMILY SSF102829 10 85 4.97E-21 T 01-11-2018 IPR036192 Cell division protein ZapA-like superfamily MLA2C4_23665 0015350430c9d142b74f50e3dfb2b701 89 Pfam PF05164 Cell division protein ZapA 11 83 1.8E-18 T 01-11-2018 IPR007838 Cell division protein ZapA-like MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 Gene3D G3DSA:2.30.42.10 310 412 2.6E-23 T 01-11-2018 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 SUPERFAMILY SSF50156 288 403 3.81E-17 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 SMART SM00228 307 395 1.7E-7 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 SUPERFAMILY SSF50494 84 304 2.14E-58 T 01-11-2018 IPR009003 Peptidase S1, PA clan MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 Gene3D G3DSA:2.40.10.10 189 309 3.1E-40 T 01-11-2018 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 Pfam PF13180 PDZ domain 307 400 4.6E-17 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 Gene3D G3DSA:2.40.10.10 72 187 1.2E-25 T 01-11-2018 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 Pfam PF13365 Trypsin-like peptidase domain 124 269 1.3E-31 T 01-11-2018 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 PRINTS PR00834 HtrA/DegQ protease family signature 136 148 2.3E-43 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 2.3E-43 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 PRINTS PR00834 HtrA/DegQ protease family signature 157 177 2.3E-43 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 PRINTS PR00834 HtrA/DegQ protease family signature 262 279 2.3E-43 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 PRINTS PR00834 HtrA/DegQ protease family signature 352 364 2.3E-43 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_18695 6bc698b23b0608e412552b03383ab639 413 PRINTS PR00834 HtrA/DegQ protease family signature 198 222 2.3E-43 T 01-11-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MLA2C4_03055 007162774900d739fd1cda520acf9ad7 248 PIRSF PIRSF032442 2 246 1.1E-81 T 01-11-2018 IPR016997 Uncharacterised conserved protein UCP032442 MLA2C4_03055 007162774900d739fd1cda520acf9ad7 248 Pfam PF13529 Peptidase_C39 like family 57 216 4.8E-42 T 01-11-2018 IPR039564 Peptidase C39-like MLA2C4_03055 007162774900d739fd1cda520acf9ad7 248 Gene3D G3DSA:3.90.70.10 50 248 8.3E-86 T 01-11-2018 MLA2C4_07965 e46e1fd3e888dea8ed06e4d13a4e3bac 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 01-11-2018 IPR033749 Polyprenyl synthetase, conserved site MLA2C4_07965 e46e1fd3e888dea8ed06e4d13a4e3bac 320 SUPERFAMILY SSF48576 7 319 6.56E-84 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily MLA2C4_07965 e46e1fd3e888dea8ed06e4d13a4e3bac 320 Pfam PF00348 Polyprenyl synthetase 31 271 7.7E-64 T 01-11-2018 IPR000092 Polyprenyl synthetase GO:0008299 MLA2C4_07965 e46e1fd3e888dea8ed06e4d13a4e3bac 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 9.8E-173 T 01-11-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 MLA2C4_07965 e46e1fd3e888dea8ed06e4d13a4e3bac 320 Gene3D G3DSA:1.10.600.10 7 320 4.1E-97 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily MLA2C4_07965 e46e1fd3e888dea8ed06e4d13a4e3bac 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 01-11-2018 IPR033749 Polyprenyl synthetase, conserved site MLA2C4_22840 a380bf3c1e1bf84f61281e14004e09fc 584 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 575 1.7E-45 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_22840 a380bf3c1e1bf84f61281e14004e09fc 584 Gene3D G3DSA:3.90.1310.30 50 234 3.2E-13 T 01-11-2018 MLA2C4_22840 a380bf3c1e1bf84f61281e14004e09fc 584 SUPERFAMILY SSF56601 188 580 1.07E-53 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_22840 a380bf3c1e1bf84f61281e14004e09fc 584 Gene3D G3DSA:3.40.710.10 240 584 5.7E-64 T 01-11-2018 MLA2C4_22840 a380bf3c1e1bf84f61281e14004e09fc 584 SUPERFAMILY SSF56519 50 234 1.31E-20 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 SMART SM00382 328 472 3.7E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Gene3D G3DSA:1.10.10.60 556 616 9.1E-12 T 01-11-2018 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Gene3D G3DSA:1.10.8.60 481 552 1.4E-14 T 01-11-2018 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Pfam PF02954 Bacterial regulatory protein, Fis family 574 614 2.9E-12 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Gene3D G3DSA:3.40.50.300 303 480 6.5E-62 T 01-11-2018 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 SUPERFAMILY SSF52540 307 544 1.22E-64 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 SUPERFAMILY SSF46689 573 616 5.73E-9 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Gene3D G3DSA:3.30.450.40 18 203 7.8E-61 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Pfam PF00158 Sigma-54 interaction domain 308 475 2.8E-67 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 Pfam PF01590 GAF domain 106 201 2.1E-7 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 395 410 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 517 526 - T 01-11-2018 IPR025944 Sigma-54 interaction domain, conserved site MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 580 597 6.2E-8 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 597 616 6.2E-8 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_14650 d510b3ee2d25c154f7f642a5e32cd817 616 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 332 345 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 Gene3D G3DSA:3.40.50.300 1 239 8.7E-76 T 01-11-2018 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 Pfam PF00005 ABC transporter 21 162 2.0E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 SMART SM00382 29 212 4.5E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 Gene3D G3DSA:2.40.50.100 240 363 8.0E-36 T 01-11-2018 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 Gene3D G3DSA:2.40.50.140 304 349 8.0E-36 T 01-11-2018 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 SUPERFAMILY SSF52540 4 243 2.26E-85 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 Pfam PF08402 TOBE domain 282 357 1.3E-8 T 01-11-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MLA2C4_20995 256c344b8b2b557f4ecb84ee414c8358 366 SUPERFAMILY SSF50331 237 365 4.13E-28 T 01-11-2018 IPR008995 Molybdate/tungstate binding, C-terminal MLA2C4_07750 15c82c7fcf473e1ea180d5fab9aba5b8 198 Pfam PF07670 Nucleoside recognition 43 150 8.2E-10 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_19730 b0f91f88f3a65e52746ca94b37f2df5a 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 1.5E-32 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_19730 b0f91f88f3a65e52746ca94b37f2df5a 288 SUPERFAMILY SSF52518 12 286 1.26E-79 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_19730 b0f91f88f3a65e52746ca94b37f2df5a 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 274 5.2E-97 T 01-11-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate MLA2C4_19730 b0f91f88f3a65e52746ca94b37f2df5a 288 Gene3D G3DSA:3.40.50.970 63 239 1.6E-30 T 01-11-2018 MLA2C4_19730 b0f91f88f3a65e52746ca94b37f2df5a 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 1.4E-22 T 01-11-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal MLA2C4_24770 b0a36ac0c80c4f6b6d8772729c337144 267 Gene3D G3DSA:3.40.50.1820 1 260 2.7E-50 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24770 b0a36ac0c80c4f6b6d8772729c337144 267 SUPERFAMILY SSF53474 3 254 2.03E-34 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24770 b0a36ac0c80c4f6b6d8772729c337144 267 Pfam PF12146 Serine aminopeptidase, S33 8 242 2.2E-58 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_16505 751b79d202bfb9bbaa21eb7cee36a966 197 Pfam PF03992 Antibiotic biosynthesis monooxygenase 22 90 1.2E-5 T 01-11-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MLA2C4_16505 751b79d202bfb9bbaa21eb7cee36a966 197 SUPERFAMILY SSF54909 13 113 4.09E-16 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_16505 751b79d202bfb9bbaa21eb7cee36a966 197 Gene3D G3DSA:3.30.70.100 20 116 9.2E-8 T 01-11-2018 MLA2C4_07320 d9c770199b84c97900f8eac4c75d6b2c 263 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 8 255 1.4E-87 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_07320 d9c770199b84c97900f8eac4c75d6b2c 263 Pfam PF02673 Bacitracin resistance protein BacA 8 257 1.7E-82 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_07320 d9c770199b84c97900f8eac4c75d6b2c 263 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 262 17.588 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 6.0E-26 T 01-11-2018 IPR000587 Creatinase, N-terminal GO:0016787 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 Gene3D G3DSA:3.90.230.10 126 353 1.4E-88 T 01-11-2018 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 Gene3D G3DSA:3.40.350.10 1 125 3.4E-36 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 01-11-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 SUPERFAMILY SSF55920 83 348 1.57E-84 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 Pfam PF00557 Metallopeptidase family M24 136 336 7.1E-68 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 6.3E-7 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 6.3E-7 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 185 198 6.3E-7 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_21960 4ffb2397b4be0f5c22870f7a568311ce 353 SUPERFAMILY SSF53092 2 125 5.75E-23 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 PIRSF PIRSF000477 1 271 7.6E-123 T 01-11-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 SUPERFAMILY SSF53167 4 271 1.44E-102 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 268 3.2E-121 T 01-11-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 269 3.0E-113 T 01-11-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 Gene3D G3DSA:3.40.50.1580 1 272 1.8E-119 T 01-11-2018 MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 01-11-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 MLA2C4_21385 a757c2b42b3f50048a1ec89781c187fe 273 Pfam PF01048 Phosphorylase superfamily 23 268 7.2E-61 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Gene3D G3DSA:3.40.50.300 8 305 1.7E-48 T 01-11-2018 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 SMART SM00382 343 538 0.4 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 SMART SM00382 20 294 0.17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Gene3D G3DSA:1.10.8.280 680 794 3.0E-12 T 01-11-2018 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Pfam PF00005 ABC transporter 337 488 5.8E-7 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Gene3D G3DSA:1.20.1580.10 120 150 1.7E-48 T 01-11-2018 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 SUPERFAMILY SSF52540 337 534 1.21E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 SUPERFAMILY SSF52540 10 299 5.24E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Gene3D G3DSA:3.40.50.300 409 535 1.0E-26 T 01-11-2018 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Gene3D G3DSA:1.20.1580.10 655 840 3.0E-12 T 01-11-2018 MLA2C4_13600 b25562710e721937cebcacf89c735ce6 1056 Gene3D G3DSA:3.40.50.300 331 405 1.3E-9 T 01-11-2018 MLA2C4_09225 f37c992df7488cbc726c7bd3f89fc7dc 161 Pfam PF00293 NUDIX domain 14 129 1.2E-16 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_09225 f37c992df7488cbc726c7bd3f89fc7dc 161 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_09225 f37c992df7488cbc726c7bd3f89fc7dc 161 Gene3D G3DSA:3.90.79.10 9 157 2.7E-30 T 01-11-2018 MLA2C4_09225 f37c992df7488cbc726c7bd3f89fc7dc 161 SUPERFAMILY SSF55811 10 136 4.6E-28 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 297 1.0E-66 T 01-11-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 3.2E-15 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 3.2E-15 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 3.2E-15 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 3.2E-15 T 01-11-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 388 5.0E-16 T 01-11-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 Gene3D G3DSA:3.20.20.10 38 297 3.2E-157 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 SUPERFAMILY SSF51419 30 299 1.25E-83 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 236 250 - T 01-11-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 SUPERFAMILY SSF50621 273 431 6.91E-51 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 429 1.3E-154 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.4E-25 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.4E-25 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.4E-25 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.4E-25 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 39.846 T 01-11-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_07500 bbb7c1b8e81ab80eff47df5670930a13 438 Gene3D G3DSA:2.40.37.10 17 427 3.2E-157 T 01-11-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 SUPERFAMILY SSF88659 102 158 5.05E-9 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 Pfam PF04542 Sigma-70 region 2 6 71 2.4E-12 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 Gene3D G3DSA:1.10.1740.10 1 74 2.0E-10 T 01-11-2018 MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 285 3.2E-119 T 01-11-2018 IPR014303 RNA polymerase sigma-70, ECF type MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 SUPERFAMILY SSF54427 169 284 2.43E-8 T 01-11-2018 IPR032710 NTF2-like domain superfamily MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 158 4.8E-22 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 Pfam PF08281 Sigma-70, region 4 106 156 5.7E-11 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 Gene3D G3DSA:1.10.10.10 109 160 5.9E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_12720 35bfd4925b6f9ded75b30c1e98a66967 289 SUPERFAMILY SSF88946 4 87 3.1E-15 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 3.5E-32 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 9 470 3.8E-233 T 01-11-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 Gene3D G3DSA:1.20.200.10 143 410 5.8E-114 T 01-11-2018 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 2.5E-7 T 01-11-2018 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 2.5E-7 T 01-11-2018 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 PRINTS PR00145 Argininosuccinate lyase family signature 137 159 2.5E-7 T 01-11-2018 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 SUPERFAMILY SSF48557 7 463 2.04E-148 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 Gene3D G3DSA:1.10.275.10 9 142 1.3E-56 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 Gene3D G3DSA:1.10.40.30 411 462 2.3E-22 T 01-11-2018 MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 Pfam PF00206 Lyase 17 345 1.1E-109 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_16345 f8378da31e2676ad0acd4e156efc78cd 476 Pfam PF10415 Fumarase C C-terminus 411 464 1.1E-20 T 01-11-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:3.40.50.300 1 203 4.7E-71 T 01-11-2018 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 60.149 T 01-11-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF50447 203 300 1.3E-30 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 3.4E-15 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 4.6E-60 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 9.2E-18 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:2.40.30.10 206 335 1.1E-52 T 01-11-2018 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF52540 6 219 9.26E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.4E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.4E-24 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:2.40.30.10 339 394 9.6E-27 T 01-11-2018 MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 3.7E-32 T 01-11-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF50465 303 395 1.35E-34 T 01-11-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MLA2C4_00660 1783a9623dddb36694ba8a0db44dcb95 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.4E-230 T 01-11-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 Pfam PF00390 Malic enzyme, N-terminal domain 82 264 2.4E-73 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 Gene3D G3DSA:3.40.50.720 272 568 6.1E-111 T 01-11-2018 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 150 179 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 301 317 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 245 263 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 410 426 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 270 286 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 186 208 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PRINTS PR00072 Malic enzyme signature 88 112 7.9E-71 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 Gene3D G3DSA:3.40.50.10380 16 271 5.3E-108 T 01-11-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 SMART SM01274 82 264 2.5E-99 T 01-11-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 ProSitePatterns PS00331 Malic enzymes signature. 270 286 - T 01-11-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 SUPERFAMILY SSF53223 4 273 1.87E-107 T 01-11-2018 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 SMART SM00919 274 532 3.3E-129 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 Pfam PF03949 Malic enzyme, NAD binding domain 274 531 1.3E-107 T 01-11-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 PIRSF PIRSF000106 2 565 1.5E-230 T 01-11-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MLA2C4_09150 a72650a3104437c987b0cf67ea9b5a0e 570 SUPERFAMILY SSF51735 274 564 5.51E-97 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_01225 2ca963b64ba05609f0c78afb529b33da 254 Gene3D G3DSA:3.20.20.140 1 253 1.9E-60 T 01-11-2018 MLA2C4_01225 2ca963b64ba05609f0c78afb529b33da 254 Pfam PF01026 TatD related DNase 4 251 1.3E-46 T 01-11-2018 IPR001130 TatD family GO:0016788 MLA2C4_01225 2ca963b64ba05609f0c78afb529b33da 254 PIRSF PIRSF005902 1 254 2.5E-57 T 01-11-2018 IPR001130 TatD family GO:0016788 MLA2C4_01225 2ca963b64ba05609f0c78afb529b33da 254 SUPERFAMILY SSF51556 3 251 5.6E-53 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 Gene3D G3DSA:3.90.76.10 91 223 1.1E-125 T 01-11-2018 MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 Gene3D G3DSA:3.40.190.10 73 548 1.1E-125 T 01-11-2018 MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 Gene3D G3DSA:3.10.105.10 317 534 1.1E-125 T 01-11-2018 MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 102 484 2.4E-81 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 PIRSF PIRSF002741 3 559 2.9E-109 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 SUPERFAMILY SSF53850 58 556 2.17E-122 T 01-11-2018 MLA2C4_01290 2061c3a20c21388a8e7e4d41adabbd95 567 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 108 130 - T 01-11-2018 IPR023765 Solute-binding protein family 5, conserved site MLA2C4_15865 5d98289216165151fddee5d21c76faea 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 32 162 5.6E-62 T 01-11-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MLA2C4_15865 5d98289216165151fddee5d21c76faea 309 PIRSF PIRSF002849 1 305 4.3E-125 T 01-11-2018 MLA2C4_15865 5d98289216165151fddee5d21c76faea 309 Gene3D G3DSA:3.40.50.300 13 179 6.3E-46 T 01-11-2018 MLA2C4_15865 5d98289216165151fddee5d21c76faea 309 Gene3D G3DSA:1.10.8.300 193 300 7.1E-32 T 01-11-2018 MLA2C4_15865 5d98289216165151fddee5d21c76faea 309 SUPERFAMILY SSF52540 3 271 2.16E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06175 90cc4cc3a0059f5bba42dd4585f4abbf 58 Pfam PF10815 ComZ 3 57 1.7E-32 T 01-11-2018 IPR024558 ComZ MLA2C4_06175 90cc4cc3a0059f5bba42dd4585f4abbf 58 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 1 58 3.0E-26 T 01-11-2018 IPR024558 ComZ MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 SUPERFAMILY SSF53901 296 417 7.77E-39 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 Gene3D G3DSA:3.40.47.10 151 415 9.6E-149 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 ProSitePatterns PS00737 Thiolases signature 2. 364 380 - T 01-11-2018 IPR020613 Thiolase, conserved site GO:0016747 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 Pfam PF02803 Thiolase, C-terminal domain 296 416 4.1E-45 T 01-11-2018 IPR020617 Thiolase, C-terminal GO:0016747 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 SUPERFAMILY SSF53901 29 294 3.29E-85 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 Gene3D G3DSA:3.40.47.10 30 301 9.6E-149 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 Pfam PF00108 Thiolase, N-terminal domain 30 288 1.3E-98 T 01-11-2018 IPR020616 Thiolase, N-terminal GO:0016747 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 109 127 - T 01-11-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 31 416 1.3E-141 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 PIRSF PIRSF000429 23 418 1.8E-124 T 01-11-2018 IPR002155 Thiolase GO:0016747 MLA2C4_27670 81314feb471488c5f1ef03e8ee4d5f89 418 ProSitePatterns PS00099 Thiolases active site. 399 412 - T 01-11-2018 IPR020610 Thiolase, active site GO:0016747 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 34.894 T 01-11-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Gene3D G3DSA:3.30.1360.30 277 421 7.3E-196 T 01-11-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 559 1.2E-111 T 01-11-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 SUPERFAMILY SSF50249 4 108 4.38E-32 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 SUPERFAMILY SSF55681 113 585 1.73E-109 T 01-11-2018 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 1.1E-17 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 586 2.4E-261 T 01-11-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Gene3D G3DSA:2.40.50.140 1 110 3.4E-34 T 01-11-2018 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 SUPERFAMILY SSF55261 294 421 7.52E-45 T 01-11-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 6.1E-27 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 6.1E-27 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 6.1E-27 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 6.1E-27 T 01-11-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Pfam PF02938 GAD domain 313 407 2.1E-32 T 01-11-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MLA2C4_22965 3cddb872df4c4de232090bf727d8e295 591 Gene3D G3DSA:3.30.930.10 121 584 7.3E-196 T 01-11-2018 MLA2C4_04590 d05530b35c2b26e663ac3d7c5e2196d8 182 SUPERFAMILY SSF52218 1 180 8.95E-43 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_04590 d05530b35c2b26e663ac3d7c5e2196d8 182 Pfam PF02525 Flavodoxin-like fold 2 176 7.7E-37 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_04590 d05530b35c2b26e663ac3d7c5e2196d8 182 Gene3D G3DSA:3.40.50.360 1 181 5.7E-55 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_10470 a8f94bf535086d906b2241ac61feb795 384 SUPERFAMILY SSF53187 233 377 2.86E-10 T 01-11-2018 MLA2C4_10470 a8f94bf535086d906b2241ac61feb795 384 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 97 372 1.7E-69 T 01-11-2018 IPR010897 Sporulation stage II, protein P MLA2C4_10470 a8f94bf535086d906b2241ac61feb795 384 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 173 377 1.3E-72 T 01-11-2018 IPR010897 Sporulation stage II, protein P MLA2C4_03245 f4e15b971ec4fd339b3b7f27694be500 334 Pfam PF01032 FecCD transport family 20 329 5.8E-92 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_03245 f4e15b971ec4fd339b3b7f27694be500 334 Gene3D G3DSA:1.10.3470.10 6 333 9.0E-93 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_03245 f4e15b971ec4fd339b3b7f27694be500 334 SUPERFAMILY SSF81345 5 329 1.7E-80 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 SUPERFAMILY SSF88659 114 190 1.92E-15 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.6E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.6E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.6E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 1.6E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 1.6E-12 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.2E-157 T 01-11-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 255 8.9E-35 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 Gene3D G3DSA:1.20.140.160 113 258 5.2E-24 T 01-11-2018 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 Gene3D G3DSA:1.10.601.10 11 110 5.1E-27 T 01-11-2018 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PIRSF PIRSF000770 159 259 5.9E-15 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PIRSF PIRSF000770 115 157 0.37 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 PIRSF PIRSF000770 15 123 4.3E-18 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.5E-84 T 01-11-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 SUPERFAMILY SSF88659 175 258 8.04E-17 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 Pfam PF04542 Sigma-70 region 2 42 110 2.4E-17 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 SUPERFAMILY SSF88946 6 110 2.75E-33 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_20400 33972a883238293f706c4d9c1cea5e1d 259 Pfam PF04545 Sigma-70, region 4 207 253 1.7E-13 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_02785 b01c9df8aa378fa7b44685cf107b2d82 144 Pfam PF01475 Ferric uptake regulator family 18 135 1.1E-40 T 01-11-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MLA2C4_02785 b01c9df8aa378fa7b44685cf107b2d82 144 SUPERFAMILY SSF46785 10 140 1.84E-43 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_02785 b01c9df8aa378fa7b44685cf107b2d82 144 Gene3D G3DSA:3.30.1490.190 90 144 8.1E-24 T 01-11-2018 MLA2C4_02785 b01c9df8aa378fa7b44685cf107b2d82 144 Gene3D G3DSA:1.10.10.10 3 89 1.2E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10105 6d883cafcc6d5e0f2313d7cebd719567 280 SUPERFAMILY SSF51658 1 259 4.01E-43 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily MLA2C4_10105 6d883cafcc6d5e0f2313d7cebd719567 280 Pfam PF01261 Xylose isomerase-like TIM barrel 22 233 1.5E-26 T 01-11-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MLA2C4_10105 6d883cafcc6d5e0f2313d7cebd719567 280 Gene3D G3DSA:3.20.20.150 1 280 3.8E-80 T 01-11-2018 MLA2C4_15860 19048372030c315a8b5f3c2f4e82d02e 105 Gene3D G3DSA:1.10.10.10 4 103 2.3E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15860 19048372030c315a8b5f3c2f4e82d02e 105 Pfam PF03551 Transcriptional regulator PadR-like family 23 86 3.6E-14 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_15860 19048372030c315a8b5f3c2f4e82d02e 105 SUPERFAMILY SSF46785 10 100 1.26E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 Pfam PF00849 RNA pseudouridylate synthase 62 196 7.4E-24 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 9.8E-51 T 01-11-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 Gene3D G3DSA:3.30.70.580 64 223 1.7E-56 T 01-11-2018 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 Pfam PF01479 S4 domain 2 48 3.1E-17 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 SMART SM00363 2 59 1.5E-16 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 SUPERFAMILY SSF55120 61 230 7.2E-44 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 Gene3D G3DSA:3.10.290.10 1 63 2.6E-23 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 01-11-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 SUPERFAMILY SSF55174 2 67 2.35E-17 T 01-11-2018 MLA2C4_07760 387653beeadc70714a6728de76cb6809 242 Gene3D G3DSA:3.30.70.1560 123 215 1.7E-56 T 01-11-2018 MLA2C4_26395 b136558333efb20c73ccf4fc0328195e 131 SMART SM00317 2 117 2.8E-8 T 01-11-2018 IPR001214 SET domain GO:0005515 MLA2C4_26395 b136558333efb20c73ccf4fc0328195e 131 Gene3D G3DSA:2.170.270.10 1 114 6.9E-30 T 01-11-2018 MLA2C4_26395 b136558333efb20c73ccf4fc0328195e 131 PIRSF PIRSF022536 1 131 7.7E-32 T 01-11-2018 IPR009207 Histone methyltransferase, PBCV type putative KEGG: 00310+2.1.1.43 MLA2C4_26395 b136558333efb20c73ccf4fc0328195e 131 Pfam PF00856 SET domain 16 111 3.6E-15 T 01-11-2018 IPR001214 SET domain GO:0005515 MLA2C4_26395 b136558333efb20c73ccf4fc0328195e 131 SUPERFAMILY SSF82199 12 113 7.33E-23 T 01-11-2018 MLA2C4_24135 3c89b50b7e72ba48135d3409a4259948 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_24135 3c89b50b7e72ba48135d3409a4259948 528 Gene3D G3DSA:3.40.50.12780 8 420 5.1E-112 T 01-11-2018 MLA2C4_24135 3c89b50b7e72ba48135d3409a4259948 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 512 2.8E-23 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_24135 3c89b50b7e72ba48135d3409a4259948 528 Pfam PF00501 AMP-binding enzyme 25 424 2.2E-81 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_24135 3c89b50b7e72ba48135d3409a4259948 528 SUPERFAMILY SSF56801 25 524 2.09E-140 T 01-11-2018 MLA2C4_24135 3c89b50b7e72ba48135d3409a4259948 528 Gene3D G3DSA:3.30.300.310 421 525 4.8E-29 T 01-11-2018 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.8E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.8E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.8E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.8E-14 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 SUPERFAMILY SSF54980 408 503 1.25E-27 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Pfam PF00679 Elongation factor G C-terminus 408 495 1.9E-25 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 314.162 T 01-11-2018 IPR006297 Elongation factor 4 GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Gene3D G3DSA:3.40.50.300 9 194 9.0E-75 T 01-11-2018 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 SUPERFAMILY SSF52540 6 238 1.7E-55 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 1.4E-19 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 3.7E-53 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 SUPERFAMILY SSF54980 301 379 1.58E-18 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Gene3D G3DSA:3.30.70.3380 377 488 3.9E-44 T 01-11-2018 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.5E-12 T 01-11-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Gene3D G3DSA:3.30.70.2570 489 563 1.0E-35 T 01-11-2018 IPR038363 LepA, C-terminal domain superfamily MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 3.1E-52 T 01-11-2018 IPR013842 GTP-binding protein LepA, C-terminal MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Gene3D G3DSA:2.40.30.10 195 294 1.7E-36 T 01-11-2018 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 Gene3D G3DSA:3.30.70.870 295 376 4.6E-35 T 01-11-2018 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 01-11-2018 IPR006297 Elongation factor 4 GO:0005525 MLA2C4_22555 5ee9ee0643dbd7f3c6d86ee2d66f5584 607 SMART SM00838 410 495 1.4E-4 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_25925 3af33323bc1c2083dd68bc18b5a127d8 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_25925 3af33323bc1c2083dd68bc18b5a127d8 261 SMART SM00382 30 225 2.2E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25925 3af33323bc1c2083dd68bc18b5a127d8 261 Pfam PF00005 ABC transporter 21 173 1.6E-21 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_25925 3af33323bc1c2083dd68bc18b5a127d8 261 SUPERFAMILY SSF52540 6 233 6.36E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25925 3af33323bc1c2083dd68bc18b5a127d8 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 3.8E-113 T 01-11-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 MLA2C4_25925 3af33323bc1c2083dd68bc18b5a127d8 261 Gene3D G3DSA:3.40.50.300 5 250 4.4E-55 T 01-11-2018 MLA2C4_01595 1c49f136d435b60381b0cb98488782c4 441 Pfam PF00860 Permease family 17 402 1.9E-42 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_01595 1c49f136d435b60381b0cb98488782c4 441 PIRSF PIRSF005353 1 441 3.5E-172 T 01-11-2018 IPR026033 Purine permease PbuG-like MLA2C4_04600 011e95b43d4577856455d2f574c9b6f6 579 SUPERFAMILY SSF53850 125 575 1.61E-83 T 01-11-2018 MLA2C4_04600 011e95b43d4577856455d2f574c9b6f6 579 Gene3D G3DSA:3.40.190.10 126 323 2.4E-47 T 01-11-2018 MLA2C4_04600 011e95b43d4577856455d2f574c9b6f6 579 Gene3D G3DSA:3.10.105.10 340 545 6.7E-19 T 01-11-2018 MLA2C4_04600 011e95b43d4577856455d2f574c9b6f6 579 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 168 489 6.5E-45 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_04600 011e95b43d4577856455d2f574c9b6f6 579 PIRSF PIRSF002741 97 577 4.5E-54 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_04600 011e95b43d4577856455d2f574c9b6f6 579 Pfam PF12793 Sugar transport-related sRNA regulator N-term 3 116 1.1E-30 T 01-11-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Gene3D G3DSA:1.10.287.130 318 377 1.7E-5 T 01-11-2018 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 SUPERFAMILY SSF103190 40 171 2.04E-40 T 01-11-2018 IPR029151 Periplasmic sensor-like domain superfamily MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Pfam PF17203 Single cache domain 3 39 173 5.8E-23 T 01-11-2018 IPR033463 Single cache domain 3 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 SMART SM00387 422 529 6.8E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 329 374 3.8E-11 T 01-11-2018 IPR039506 SpoOB, alpha-helical domain MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 SUPERFAMILY SSF55785 215 314 1.12E-7 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Pfam PF00989 PAS fold 216 315 7.9E-8 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 6.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 526 6.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 6.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Gene3D G3DSA:3.30.450.20 33 174 4.4E-46 T 01-11-2018 MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 527 8.2E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Gene3D G3DSA:3.30.565.10 393 531 1.3E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 SUPERFAMILY SSF55874 397 526 2.6E-26 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03065 1f436149451c903989d0960dafae44b8 532 Gene3D G3DSA:3.30.450.20 201 317 9.4E-23 T 01-11-2018 MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 Gene3D G3DSA:3.40.50.300 1 237 5.7E-56 T 01-11-2018 MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 Gene3D G3DSA:3.40.50.300 251 494 1.2E-41 T 01-11-2018 MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 SMART SM00382 29 218 1.8E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 Pfam PF00005 ABC transporter 21 169 2.1E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 Pfam PF00005 ABC transporter 274 429 7.7E-18 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 SUPERFAMILY SSF52540 256 489 8.84E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 SUPERFAMILY SSF52540 3 225 1.77E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19825 f62d5142bb997cacc56db2b60fcce114 510 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_13855 fa210027d88d2563cde8306235c8dbdf 643 Pfam PF02687 FtsX-like permease family 90 181 1.2E-9 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_13855 fa210027d88d2563cde8306235c8dbdf 643 PIRSF PIRSF018968 1 641 4.3E-125 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_09390 db12cc76c51c58ce1977c2b38f0ea6fd 228 Pfam PF04239 Protein of unknown function (DUF421) 88 205 3.3E-32 T 01-11-2018 IPR007353 Protein of unknown function DUF421 MLA2C4_09390 db12cc76c51c58ce1977c2b38f0ea6fd 228 Gene3D G3DSA:3.30.240.20 170 228 4.3E-19 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_09390 db12cc76c51c58ce1977c2b38f0ea6fd 228 Gene3D G3DSA:3.30.240.20 80 156 1.5E-25 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_03255 bc25e041d8fadd51cc3973a4a1369c84 273 SMART SM00382 29 249 6.4E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_03255 bc25e041d8fadd51cc3973a4a1369c84 273 Pfam PF00005 ABC transporter 21 168 2.1E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03255 bc25e041d8fadd51cc3973a4a1369c84 273 SUPERFAMILY SSF52540 4 232 3.41E-63 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03255 bc25e041d8fadd51cc3973a4a1369c84 273 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_03255 bc25e041d8fadd51cc3973a4a1369c84 273 Gene3D G3DSA:3.40.50.300 1 252 7.9E-70 T 01-11-2018 MLA2C4_26185 18b68c7de5e6971089a707ca813ae30d 73 SMART SM00530 6 61 4.7E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_26185 18b68c7de5e6971089a707ca813ae30d 73 Pfam PF01381 Helix-turn-helix 7 61 3.8E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_26185 18b68c7de5e6971089a707ca813ae30d 73 Gene3D G3DSA:1.10.260.40 2 66 5.9E-24 T 01-11-2018 MLA2C4_26185 18b68c7de5e6971089a707ca813ae30d 73 SUPERFAMILY SSF47413 1 69 5.09E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_20890 1bef3bcfbabffb640aedd8bde49a0fb3 220 SUPERFAMILY SSF140423 21 211 1.83E-58 T 01-11-2018 IPR036785 YkyA-like superfamily MLA2C4_20890 1bef3bcfbabffb640aedd8bde49a0fb3 220 Gene3D G3DSA:1.20.120.570 13 209 4.8E-41 T 01-11-2018 IPR036785 YkyA-like superfamily MLA2C4_20890 1bef3bcfbabffb640aedd8bde49a0fb3 220 Pfam PF10368 Putative cell-wall binding lipoprotein 13 213 6.0E-65 T 01-11-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like MLA2C4_04815 1341e6f6999b7ee5a7a662d9e333eb61 485 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 75 371 2.4E-31 T 01-11-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MLA2C4_04815 1341e6f6999b7ee5a7a662d9e333eb61 485 PIRSF PIRSF016636 1 485 1.7E-149 T 01-11-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MLA2C4_04815 1341e6f6999b7ee5a7a662d9e333eb61 485 PIRSF PIRSF500217 1 485 1.5E-145 T 01-11-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MLA2C4_26930 1ec1f85b2ce325a7fab01bc6dddd92e1 234 Gene3D G3DSA:3.20.20.370 2 234 1.6E-79 T 01-11-2018 MLA2C4_26930 1ec1f85b2ce325a7fab01bc6dddd92e1 234 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 2 234 41.035 T 01-11-2018 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 MLA2C4_26930 1ec1f85b2ce325a7fab01bc6dddd92e1 234 Pfam PF04794 YdjC-like protein 3 228 3.7E-61 T 01-11-2018 IPR006879 Carbohydrate deacetylase YdjC-like MLA2C4_26930 1ec1f85b2ce325a7fab01bc6dddd92e1 234 SUPERFAMILY SSF88713 1 229 4.45E-73 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 SUPERFAMILY SSF81333 2 71 6.28E-21 T 01-11-2018 IPR035921 F/V-ATP synthase subunit C superfamily MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Gene3D G3DSA:1.20.20.10 1 72 1.0E-28 T 01-11-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Hamap MF_01396 ATP synthase subunit c [atpH]. 5 70 16.107 T 01-11-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Pfam PF00137 ATP synthase subunit C 6 68 2.1E-15 T 01-11-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 7 26 1.4E-20 T 01-11-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 45 70 1.4E-20 T 01-11-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 28 43 1.4E-20 T 01-11-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 ProSitePatterns PS00605 ATP synthase c subunit signature. 35 56 - T 01-11-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27485 cf1e8b5bebfc95161e321eb0aabaf5f3 72 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 16 70 8.9E-24 T 01-11-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Gene3D G3DSA:3.40.1190.10 91 292 7.0E-54 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Pfam PF01225 Mur ligase family, catalytic domain 4 101 3.7E-23 T 01-11-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Pfam PF08245 Mur ligase middle domain 106 275 5.3E-24 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 425 1.7E-135 T 01-11-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 SUPERFAMILY SSF53244 294 428 2.01E-35 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Gene3D G3DSA:3.90.190.20 293 436 1.1E-40 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 SUPERFAMILY SSF53623 87 293 1.09E-58 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 378 3.4E-18 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 SUPERFAMILY SSF51984 4 88 2.09E-20 T 01-11-2018 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 35.357 T 01-11-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_24380 fcc5d88154c16b5f6e7ae8cdfc6b9208 436 Gene3D G3DSA:3.40.50.720 3 89 9.2E-21 T 01-11-2018 MLA2C4_05045 913990b3502e7d5eb747efed59238279 113 SUPERFAMILY SSF46785 9 95 1.23E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05045 913990b3502e7d5eb747efed59238279 113 Gene3D G3DSA:1.10.10.10 1 111 1.7E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05045 913990b3502e7d5eb747efed59238279 113 Pfam PF03551 Transcriptional regulator PadR-like family 12 84 2.0E-15 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_27350 364c1aa13a6c58d8e92a63e0ac3d5840 280 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_27350 364c1aa13a6c58d8e92a63e0ac3d5840 280 Gene3D G3DSA:3.40.50.300 2 241 3.5E-65 T 01-11-2018 MLA2C4_27350 364c1aa13a6c58d8e92a63e0ac3d5840 280 Pfam PF00005 ABC transporter 20 160 3.0E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_27350 364c1aa13a6c58d8e92a63e0ac3d5840 280 SUPERFAMILY SSF52540 4 226 2.41E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27350 364c1aa13a6c58d8e92a63e0ac3d5840 280 SMART SM00382 29 216 2.5E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17000 6223c24698cece7f226d281dcc0f58a2 193 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 104 188 9.668 T 01-11-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 MLA2C4_17000 6223c24698cece7f226d281dcc0f58a2 193 SUPERFAMILY SSF52540 2 185 1.77E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17000 6223c24698cece7f226d281dcc0f58a2 193 Pfam PF13671 AAA domain 5 144 3.0E-11 T 01-11-2018 MLA2C4_17000 6223c24698cece7f226d281dcc0f58a2 193 Gene3D G3DSA:3.40.50.300 3 190 7.0E-12 T 01-11-2018 MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 Gene3D G3DSA:1.10.486.10 387 550 1.9E-130 T 01-11-2018 MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 275 1.7E-87 T 01-11-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 Gene3D G3DSA:3.40.50.300 284 637 1.9E-130 T 01-11-2018 MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 Pfam PF13361 UvrD-like helicase C-terminal domain 281 619 1.2E-74 T 01-11-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 Gene3D G3DSA:1.10.10.160 115 191 6.6E-110 T 01-11-2018 IPR013986 DExx box DNA helicase domain superfamily MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 SUPERFAMILY SSF52540 6 646 1.47E-187 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 7 744 0.0 T 01-11-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 MLA2C4_01830 30eebb20ac0263a4557ce6035f5aeb75 747 Gene3D G3DSA:3.40.50.300 11 278 6.6E-110 T 01-11-2018 MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 SUPERFAMILY SSF52540 2 352 9.46E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 348 6.8E-21 T 01-11-2018 IPR003395 RecF/RecN/SMC, N-terminal MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 375 104.824 T 01-11-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 Gene3D G3DSA:3.40.50.300 6 345 1.8E-113 T 01-11-2018 MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 Gene3D G3DSA:1.20.1050.90 119 311 1.8E-113 T 01-11-2018 MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 01-11-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 366 3.5E-132 T 01-11-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MLA2C4_00020 232471a9c14d0151a3d5af35bd3476fd 375 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 01-11-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MLA2C4_16655 1840fcbe29955135d4295b4ce90b8b38 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 1.5E-12 T 01-11-2018 MLA2C4_16655 1840fcbe29955135d4295b4ce90b8b38 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 1.5E-12 T 01-11-2018 MLA2C4_16655 1840fcbe29955135d4295b4ce90b8b38 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 71 96 1.5E-12 T 01-11-2018 MLA2C4_16655 1840fcbe29955135d4295b4ce90b8b38 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 301 313 1.5E-12 T 01-11-2018 MLA2C4_16655 1840fcbe29955135d4295b4ce90b8b38 510 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 109 1.3E-7 T 01-11-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_16655 1840fcbe29955135d4295b4ce90b8b38 510 Pfam PF00361 Proton-conducting membrane transporter 122 402 2.8E-58 T 01-11-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 2.2E-14 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 657 1.3E-9 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 711 757 5.4E-15 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 597 6.0E-12 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 509 552 7.5E-13 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 761 805 1.8E-13 T 01-11-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 808 0.0 T 01-11-2018 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 809 25.182 T 01-11-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 473 6.5E-161 T 01-11-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Gene3D G3DSA:1.10.268.10 371 460 6.6E-219 T 01-11-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 SMART SM00434 13 466 6.7E-294 T 01-11-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Gene3D G3DSA:2.120.10.90 498 808 8.0E-133 T 01-11-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Gene3D G3DSA:3.30.1360.40 238 334 6.6E-219 T 01-11-2018 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 Gene3D G3DSA:3.90.199.10 34 487 6.6E-219 T 01-11-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 SUPERFAMILY SSF56719 32 488 2.88E-183 T 01-11-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MLA2C4_00030 5bd50c1da5ca32b99708c46e5aa7e03e 823 SUPERFAMILY SSF101904 501 821 2.88E-115 T 01-11-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.2E-69 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 Gene3D G3DSA:3.30.390.30 353 473 5.7E-46 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 7.9E-178 T 01-11-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-36 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.7E-36 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.7E-36 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.7E-36 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.7E-36 T 01-11-2018 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 Gene3D G3DSA:3.50.50.60 163 285 6.3E-113 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 SUPERFAMILY SSF55424 350 472 3.09E-41 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 PIRSF PIRSF000350 1 470 7.6E-86 T 01-11-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 8.3E-38 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 SUPERFAMILY SSF51905 1 377 4.19E-59 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 2.5E-61 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 01-11-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MLA2C4_21770 0c96872365c88442d4e4cb118bce4e49 473 Gene3D G3DSA:3.50.50.60 5 341 6.3E-113 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_00595 09c64c0a9923ff194d6313c7382bc600 59 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 57 2.7E-21 T 01-11-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00595 09c64c0a9923ff194d6313c7382bc600 59 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 4 59 5.6E-23 T 01-11-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MLA2C4_00595 09c64c0a9923ff194d6313c7382bc600 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 56 12.607 T 01-11-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00595 09c64c0a9923ff194d6313c7382bc600 59 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 6 34 - T 01-11-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MLA2C4_00595 09c64c0a9923ff194d6313c7382bc600 59 Gene3D G3DSA:1.20.5.1030 1 57 2.2E-19 T 01-11-2018 IPR038379 SecE superfamily MLA2C4_27240 c3220ff3fc240823043f3531833f52d0 314 Gene3D G3DSA:2.60.120.10 1 225 1.9E-90 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_27240 c3220ff3fc240823043f3531833f52d0 314 Pfam PF01238 Phosphomannose isomerase type I 5 313 8.2E-42 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MLA2C4_27240 c3220ff3fc240823043f3531833f52d0 314 SUPERFAMILY SSF51182 2 312 3.93E-100 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_27240 c3220ff3fc240823043f3531833f52d0 314 Gene3D G3DSA:2.60.120.10 228 314 1.6E-26 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_27240 c3220ff3fc240823043f3531833f52d0 314 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 100 313 4.3E-54 T 01-11-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 MLA2C4_27240 c3220ff3fc240823043f3531833f52d0 314 PIRSF PIRSF036894 2 314 3.1E-126 T 01-11-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 MLA2C4_28030 29822fda93da1df2754c3cca242fc443 208 SUPERFAMILY SSF52218 1 208 1.19E-46 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_28030 29822fda93da1df2754c3cca242fc443 208 Gene3D G3DSA:3.40.50.360 1 208 1.8E-59 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_28030 29822fda93da1df2754c3cca242fc443 208 Pfam PF02525 Flavodoxin-like fold 3 203 1.2E-40 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_28030 29822fda93da1df2754c3cca242fc443 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.735 T 01-11-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MLA2C4_26610 f3fdfc9550caf4be237100dfb01aa128 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 9.0E-22 T 01-11-2018 IPR012452 Protein of unknown function DUF1657 MLA2C4_08170 0ff87b5d4274546787b3267aa2cc34d8 63 Pfam PF14178 YppF-like protein 1 58 3.2E-28 T 01-11-2018 IPR025553 YppF-like protein MLA2C4_08170 0ff87b5d4274546787b3267aa2cc34d8 63 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 58 8.0E-7 T 01-11-2018 MLA2C4_15465 3bba54d2c11f32b395ac3608a92d3558 229 Gene3D G3DSA:3.40.50.10300 2 223 8.2E-51 T 01-11-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MLA2C4_15465 3bba54d2c11f32b395ac3608a92d3558 229 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 1 182 5.8E-30 T 01-11-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MLA2C4_15465 3bba54d2c11f32b395ac3608a92d3558 229 SUPERFAMILY SSF102645 2 222 4.84E-43 T 01-11-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 SUPERFAMILY SSF53254 3 202 3.4E-59 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 SMART SM00855 4 158 2.4E-19 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 01-11-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 PIRSF PIRSF000709 1 176 2.1E-22 T 01-11-2018 MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 Gene3D G3DSA:3.40.50.1240 2 203 1.3E-67 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 PRINTS PR00991 6-phosphofructo-2-kinase family signature 86 102 6.1E-5 T 01-11-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|Reactome: R-HSA-70171 MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 PRINTS PR00991 6-phosphofructo-2-kinase family signature 5 27 6.1E-5 T 01-11-2018 IPR003094 Fructose-2,6-bisphosphatase GO:0003824|GO:0005524|GO:0006003 KEGG: 00051+2.7.1.105+3.1.3.46|Reactome: R-HSA-70171 MLA2C4_10345 4db0c7725203522236a0d8b0faba6a68 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 5.9E-60 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_05075 4e85b4947652fe6d3bd78d5058e010f5 291 SUPERFAMILY SSF140453 5 92 3.92E-9 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_05075 4e85b4947652fe6d3bd78d5058e010f5 291 Pfam PF06013 Proteins of 100 residues with WXG 6 90 3.4E-10 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_05075 4e85b4947652fe6d3bd78d5058e010f5 291 Gene3D G3DSA:1.10.287.850 2 92 2.6E-24 T 01-11-2018 MLA2C4_05075 4e85b4947652fe6d3bd78d5058e010f5 291 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 92 8.2E-18 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 PIRSF PIRSF004803 1 555 7.5E-249 T 01-11-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 407 3.0E-9 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 SMART SM00849 21 215 4.9E-26 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 Gene3D G3DSA:3.40.50.10710 207 357 4.1E-194 T 01-11-2018 MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 Gene3D G3DSA:3.60.15.10 12 442 4.1E-194 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 Gene3D G3DSA:3.10.20.580 449 555 3.7E-40 T 01-11-2018 MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 1.7E-15 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 01-11-2018 IPR001587 Ribonuclease J, conserved site MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 48.253 T 01-11-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 SUPERFAMILY SSF56281 11 423 2.03E-96 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_20790 c3e1b2f6ea388a911b447de4ffe3b245 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 2.1E-232 T 01-11-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 MLA2C4_07190 3c39451bc4e4411664412bba99bb017e 232 Pfam PF00005 ABC transporter 21 155 3.3E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_07190 3c39451bc4e4411664412bba99bb017e 232 SUPERFAMILY SSF52540 4 215 1.16E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07190 3c39451bc4e4411664412bba99bb017e 232 Gene3D G3DSA:3.40.50.300 1 231 5.0E-48 T 01-11-2018 MLA2C4_07190 3c39451bc4e4411664412bba99bb017e 232 SMART SM00382 29 204 1.0E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_08625 7084307fb50aed4f3afb8203e446c4a5 434 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 353 2.8E-62 T 01-11-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_08625 7084307fb50aed4f3afb8203e446c4a5 434 SUPERFAMILY SSF52540 93 358 1.51E-80 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08625 7084307fb50aed4f3afb8203e446c4a5 434 SMART SM00382 157 337 3.3E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_08625 7084307fb50aed4f3afb8203e446c4a5 434 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 3 433 9.4E-145 T 01-11-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_08625 7084307fb50aed4f3afb8203e446c4a5 434 Gene3D G3DSA:3.40.50.12240 17 434 5.3E-121 T 01-11-2018 MLA2C4_21865 f18f8f3c2497e81e85e2b769315250b2 452 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 441 30.308 T 01-11-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_21865 f18f8f3c2497e81e85e2b769315250b2 452 Pfam PF13742 OB-fold nucleic acid binding domain 6 101 7.7E-33 T 01-11-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MLA2C4_21865 f18f8f3c2497e81e85e2b769315250b2 452 Pfam PF02601 Exonuclease VII, large subunit 124 438 9.4E-99 T 01-11-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MLA2C4_21865 f18f8f3c2497e81e85e2b769315250b2 452 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 351 3.6E-140 T 01-11-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 SUPERFAMILY SSF53756 3 476 3.11E-135 T 01-11-2018 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 474 2.7E-180 T 01-11-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 Gene3D G3DSA:3.40.50.2000 3 472 5.1E-186 T 01-11-2018 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 Pfam PF00534 Glycosyl transferases group 1 287 437 2.4E-19 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 46.848 T 01-11-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 Pfam PF08323 Starch synthase catalytic domain 2 237 1.4E-83 T 01-11-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MLA2C4_25310 f375ecab7c7fce32af9cc55bd4b4bb84 476 Gene3D G3DSA:3.40.50.2000 250 458 5.1E-186 T 01-11-2018 MLA2C4_04455 b94ae245f3e19b32efc97a76fe91fad8 122 Pfam PF13157 Protein of unknown function (DUF3992) 23 117 7.5E-37 T 01-11-2018 IPR025055 Protein of unknown function DUF3992 MLA2C4_04105 9ae0a2018552f823c2a8816f1a123b13 505 PIRSF PIRSF005690 6 496 2.5E-133 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_04105 9ae0a2018552f823c2a8816f1a123b13 505 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 25 481 4.0E-146 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 SMART SM00448 4 119 1.3E-31 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 153 263 2.0E-59 T 01-11-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 Gene3D G3DSA:1.10.10.10 145 264 2.2E-55 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 Gene3D G3DSA:3.40.50.2300 1 132 1.7E-32 T 01-11-2018 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 SUPERFAMILY SSF46894 148 262 1.02E-48 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 Pfam PF00072 Response regulator receiver domain 6 119 3.5E-27 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 PIRSF PIRSF002937 1 264 6.8E-133 T 01-11-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 SUPERFAMILY SSF52172 2 127 2.56E-32 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 154 257 1.2E-45 T 01-11-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 MLA2C4_21820 4882d8129c0cd783c30f78b9d4a0310f 264 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 264 3.8E-138 T 01-11-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 MLA2C4_24785 3c740f987bff5a4510aff9cbe38fcd81 380 Gene3D G3DSA:3.40.50.2000 1 195 1.0E-27 T 01-11-2018 MLA2C4_24785 3c740f987bff5a4510aff9cbe38fcd81 380 Pfam PF13439 Glycosyltransferase Family 4 14 177 1.4E-22 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MLA2C4_24785 3c740f987bff5a4510aff9cbe38fcd81 380 Gene3D G3DSA:3.40.50.2000 196 354 3.3E-38 T 01-11-2018 MLA2C4_24785 3c740f987bff5a4510aff9cbe38fcd81 380 Pfam PF00534 Glycosyl transferases group 1 189 347 6.0E-32 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_24785 3c740f987bff5a4510aff9cbe38fcd81 380 SUPERFAMILY SSF53756 2 372 5.65E-79 T 01-11-2018 MLA2C4_04340 c9c2b5b3baeb5eb6b819bdb65e8c36c6 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 358 5.7E-147 T 01-11-2018 IPR008589 Protein of unknown function DUF871, prokaryotic MLA2C4_04340 c9c2b5b3baeb5eb6b819bdb65e8c36c6 362 Gene3D G3DSA:2.40.100.10 242 359 1.1E-42 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_04340 c9c2b5b3baeb5eb6b819bdb65e8c36c6 362 SUPERFAMILY SSF51445 1 242 2.11E-95 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_04340 c9c2b5b3baeb5eb6b819bdb65e8c36c6 362 Gene3D G3DSA:3.20.20.70 1 241 3.7E-93 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_04340 c9c2b5b3baeb5eb6b819bdb65e8c36c6 362 SUPERFAMILY SSF50891 246 358 1.63E-40 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 23 427 2.7E-169 T 01-11-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 Gene3D G3DSA:1.20.1270.20 27 111 2.6E-29 T 01-11-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 SUPERFAMILY SSF56821 1 427 1.04E-149 T 01-11-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 Pfam PF03063 Prismane/CO dehydrogenase family 80 424 4.4E-105 T 01-11-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 428 16.586 T 01-11-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 Pfam PF03063 Prismane/CO dehydrogenase family 1 79 3.7E-14 T 01-11-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 Gene3D G3DSA:3.40.50.2030 257 427 2.7E-56 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_17910 b609caca7f3cae562acc79ef349412d8 428 Gene3D G3DSA:3.40.50.2030 113 256 4.2E-60 T 01-11-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MLA2C4_18715 c42cd06886c5c73019fb3df5eb1e9de6 198 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 191 1.2E-62 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_18715 c42cd06886c5c73019fb3df5eb1e9de6 198 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 192 20.259 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_18715 c42cd06886c5c73019fb3df5eb1e9de6 198 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 183 5.3E-52 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_18715 c42cd06886c5c73019fb3df5eb1e9de6 198 SMART SM01207 9 184 3.6E-82 T 01-11-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MLA2C4_01345 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_01330 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_01340 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_01325 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_01335 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_00770 ea76950521717caeb5e61bd310cc1305 146 Gene3D G3DSA:3.100.10.10 66 146 1.1E-28 T 01-11-2018 MLA2C4_00770 ea76950521717caeb5e61bd310cc1305 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.747 T 01-11-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MLA2C4_00770 ea76950521717caeb5e61bd310cc1305 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 01-11-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00770 ea76950521717caeb5e61bd310cc1305 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 5.3E-38 T 01-11-2018 IPR021131 Ribosomal protein L18e/L15P MLA2C4_00770 ea76950521717caeb5e61bd310cc1305 146 SUPERFAMILY SSF52080 4 144 2.75E-50 T 01-11-2018 IPR036227 Ribosomal L18e/L15P superfamily MLA2C4_00770 ea76950521717caeb5e61bd310cc1305 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 3.0E-56 T 01-11-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20735 6403e3734255905887dc96967c141720 464 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 90 342 7.4E-24 T 01-11-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MLA2C4_20735 6403e3734255905887dc96967c141720 464 PIRSF PIRSF500217 1 464 1.8E-151 T 01-11-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MLA2C4_20735 6403e3734255905887dc96967c141720 464 PIRSF PIRSF016636 1 464 2.2E-145 T 01-11-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MLA2C4_02640 18b8e9abd85fc475a91020618f679622 515 Gene3D G3DSA:3.90.550.10 263 460 3.7E-22 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02640 18b8e9abd85fc475a91020618f679622 515 Pfam PF00535 Glycosyl transferase family 2 274 389 1.8E-14 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_02640 18b8e9abd85fc475a91020618f679622 515 Pfam PF00535 Glycosyl transferase family 2 6 120 2.5E-16 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_02640 18b8e9abd85fc475a91020618f679622 515 SUPERFAMILY SSF53448 272 433 4.74E-20 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02640 18b8e9abd85fc475a91020618f679622 515 SUPERFAMILY SSF53448 3 163 4.78E-23 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02640 18b8e9abd85fc475a91020618f679622 515 Gene3D G3DSA:3.90.550.10 1 230 1.3E-25 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_09195 6a5a617520299363b3348eebc587e1f4 151 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 133 2.3E-6 T 01-11-2018 MLA2C4_09195 6a5a617520299363b3348eebc587e1f4 151 SUPERFAMILY SSF54593 3 146 8.17E-33 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_09195 6a5a617520299363b3348eebc587e1f4 151 Gene3D G3DSA:3.10.180.10 1 151 6.3E-62 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_12895 e77895104c6da1e3497d6c9ad4305764 174 Pfam PF08761 dUTPase 3 64 3.4E-8 T 01-11-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 MLA2C4_12895 e77895104c6da1e3497d6c9ad4305764 174 Pfam PF08761 dUTPase 76 174 7.3E-14 T 01-11-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 MLA2C4_12895 e77895104c6da1e3497d6c9ad4305764 174 SUPERFAMILY SSF101386 2 174 1.11E-28 T 01-11-2018 MLA2C4_12895 e77895104c6da1e3497d6c9ad4305764 174 PIRSF PIRSF030140 1 174 3.8E-31 T 01-11-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 MLA2C4_15635 0962ab6f479b4a0f33206f8ceb3ca5d2 534 SUPERFAMILY SSF56801 6 520 3.66E-138 T 01-11-2018 MLA2C4_15635 0962ab6f479b4a0f33206f8ceb3ca5d2 534 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 504 2.5E-13 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_15635 0962ab6f479b4a0f33206f8ceb3ca5d2 534 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_15635 0962ab6f479b4a0f33206f8ceb3ca5d2 534 Pfam PF00501 AMP-binding enzyme 14 422 3.4E-96 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_15635 0962ab6f479b4a0f33206f8ceb3ca5d2 534 Gene3D G3DSA:3.40.50.12780 4 418 2.4E-106 T 01-11-2018 MLA2C4_15635 0962ab6f479b4a0f33206f8ceb3ca5d2 534 Gene3D G3DSA:3.30.300.310 419 518 2.8E-24 T 01-11-2018 MLA2C4_00520 3070d6f8989a15fea808e0aac5998c0f 354 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 54 253 5.6E-75 T 01-11-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 MLA2C4_00520 3070d6f8989a15fea808e0aac5998c0f 354 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 350 38.743 T 01-11-2018 IPR023660 Protein arginine kinase GO:0016775 MLA2C4_00520 3070d6f8989a15fea808e0aac5998c0f 354 Gene3D G3DSA:3.30.590.10 8 263 1.4E-73 T 01-11-2018 MLA2C4_00520 3070d6f8989a15fea808e0aac5998c0f 354 SUPERFAMILY SSF55931 5 268 5.89E-89 T 01-11-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MLA2C4_00520 3070d6f8989a15fea808e0aac5998c0f 354 ProSitePatterns PS00112 Phosphagen kinase active site signature. 167 173 - T 01-11-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 MLA2C4_07845 2959026bfc15df6d51a95f454cc64b1a 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 90 4.1E-27 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_07845 2959026bfc15df6d51a95f454cc64b1a 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 101 191 4.6E-15 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_07845 2959026bfc15df6d51a95f454cc64b1a 202 PIRSF PIRSF029008 1 197 1.5E-64 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_07845 2959026bfc15df6d51a95f454cc64b1a 202 Gene3D G3DSA:3.30.70.1950 104 196 4.2E-27 T 01-11-2018 IPR038471 MecA, C-terminal domain superfamily MLA2C4_07845 2959026bfc15df6d51a95f454cc64b1a 202 Hamap MF_01124 Adapter protein MecA [mecA]. 1 195 24.833 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_02940 f3c6741e84332a8d90c3fe1a0ff39b96 162 Pfam PF00588 SpoU rRNA Methylase family 3 145 3.3E-36 T 01-11-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MLA2C4_02940 f3c6741e84332a8d90c3fe1a0ff39b96 162 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.881 T 01-11-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MLA2C4_02940 f3c6741e84332a8d90c3fe1a0ff39b96 162 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 2.4E-67 T 01-11-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MLA2C4_02940 f3c6741e84332a8d90c3fe1a0ff39b96 162 Gene3D G3DSA:3.40.1280.10 1 162 8.9E-75 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MLA2C4_02940 f3c6741e84332a8d90c3fe1a0ff39b96 162 PIRSF PIRSF029256 2 157 7.5E-69 T 01-11-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MLA2C4_02940 f3c6741e84332a8d90c3fe1a0ff39b96 162 SUPERFAMILY SSF75217 3 155 5.3E-46 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases MLA2C4_20685 ae9ee70334b61e73a28e21d257db1773 208 PIRSF PIRSF021332 1 208 6.7E-95 T 01-11-2018 IPR009403 Protein of unknown function UPF0637 MLA2C4_20685 ae9ee70334b61e73a28e21d257db1773 208 Gene3D G3DSA:3.30.930.20 1 208 1.6E-86 T 01-11-2018 MLA2C4_20685 ae9ee70334b61e73a28e21d257db1773 208 SUPERFAMILY SSF142913 3 206 4.97E-83 T 01-11-2018 MLA2C4_20685 ae9ee70334b61e73a28e21d257db1773 208 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 2.2E-85 T 01-11-2018 IPR009403 Protein of unknown function UPF0637 MLA2C4_20685 ae9ee70334b61e73a28e21d257db1773 208 Hamap MF_01851 UPF0637 protein . 5 205 39.554 T 01-11-2018 IPR009403 Protein of unknown function UPF0637 MLA2C4_07735 9a3b9230d6d5a96a7c9e8a28e64697d4 163 Pfam PF13047 Protein of unknown function (DUF3907) 10 157 2.0E-63 T 01-11-2018 IPR025013 Protein of unknown function DUF3907 MLA2C4_13100 ccd5536f8ddc3603cac6cffdabca94af 354 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 49 167 1.2E-11 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_13100 ccd5536f8ddc3603cac6cffdabca94af 354 SMART SM00644 34 168 1.4E-21 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_13100 ccd5536f8ddc3603cac6cffdabca94af 354 SUPERFAMILY SSF55846 34 186 1.44E-32 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_13100 ccd5536f8ddc3603cac6cffdabca94af 354 Gene3D G3DSA:3.40.80.10 22 200 2.4E-53 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_13100 ccd5536f8ddc3603cac6cffdabca94af 354 Gene3D G3DSA:2.30.30.40 221 278 5.2E-7 T 01-11-2018 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 SUPERFAMILY SSF56176 4 217 6.07E-66 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 Gene3D G3DSA:1.10.45.10 418 457 1.2E-8 T 01-11-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 SUPERFAMILY SSF55103 220 457 1.64E-62 T 01-11-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 4.3E-57 T 01-11-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 Gene3D G3DSA:3.30.465.40 5 237 1.9E-72 T 01-11-2018 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 Gene3D G3DSA:3.30.70.2740 336 417 1.6E-10 T 01-11-2018 MLA2C4_18240 40f7ab1c9911a59f6888fd4b621e92b2 463 Pfam PF01565 FAD binding domain 43 180 1.0E-40 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MLA2C4_21125 6d4de38e5c476d04c2f4f6d009e88681 170 Gene3D G3DSA:2.60.120.10 1 170 6.6E-61 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_21125 6d4de38e5c476d04c2f4f6d009e88681 170 SUPERFAMILY SSF51182 8 170 8.17E-32 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_21125 6d4de38e5c476d04c2f4f6d009e88681 170 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 170 26.869 T 01-11-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 MLA2C4_21125 6d4de38e5c476d04c2f4f6d009e88681 170 Pfam PF03079 ARD/ARD' family 3 168 9.8E-44 T 01-11-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 MLA2C4_18990 c9b703854e5ac38affa043718eb7f3a4 190 SUPERFAMILY SSF52317 1 163 2.66E-32 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_18990 c9b703854e5ac38affa043718eb7f3a4 190 Pfam PF01965 DJ-1/PfpI family 2 155 3.4E-28 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_18990 c9b703854e5ac38affa043718eb7f3a4 190 Gene3D G3DSA:3.40.50.880 1 183 7.1E-39 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_27835 0fa20371b0cadb220649bb6efea18fe0 61 Pfam PF01361 Tautomerase enzyme 2 60 8.3E-25 T 01-11-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 MLA2C4_27835 0fa20371b0cadb220649bb6efea18fe0 61 Gene3D G3DSA:3.30.429.10 1 60 3.4E-28 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily MLA2C4_27835 0fa20371b0cadb220649bb6efea18fe0 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 2.3E-27 T 01-11-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 MLA2C4_27835 0fa20371b0cadb220649bb6efea18fe0 61 SUPERFAMILY SSF55331 2 60 3.93E-20 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily MLA2C4_15960 5fc3595a6c5c18a518a5191098663132 219 SUPERFAMILY SSF53474 11 192 3.09E-6 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_15960 5fc3595a6c5c18a518a5191098663132 219 PIRSF PIRSF033634 1 214 1.8E-73 T 01-11-2018 IPR017018 Uncharacterised conserved protein UCP033634 MLA2C4_15960 5fc3595a6c5c18a518a5191098663132 219 Gene3D G3DSA:3.40.50.1820 9 199 7.3E-6 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24790 1f1a73b707a106cc3593a4bacbe747e6 200 Gene3D G3DSA:3.90.550.10 7 200 1.2E-49 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_24790 1f1a73b707a106cc3593a4bacbe747e6 200 SUPERFAMILY SSF53448 1 193 3.22E-30 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_24790 1f1a73b707a106cc3593a4bacbe747e6 200 Pfam PF12804 MobA-like NTP transferase domain 6 155 9.6E-31 T 01-11-2018 IPR025877 MobA-like NTP transferase MLA2C4_24790 1f1a73b707a106cc3593a4bacbe747e6 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 2 193 23.68 T 01-11-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MLA2C4_26300 53e77fe3f854062b11e6946c799741c8 192 Gene3D G3DSA:3.40.50.450 1 191 2.9E-77 T 01-11-2018 MLA2C4_26300 53e77fe3f854062b11e6946c799741c8 192 SUPERFAMILY SSF102405 1 179 1.53E-58 T 01-11-2018 MLA2C4_26300 53e77fe3f854062b11e6946c799741c8 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 179 4.3E-62 T 01-11-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MLA2C4_26300 53e77fe3f854062b11e6946c799741c8 192 Pfam PF03641 Possible lysine decarboxylase 46 175 2.8E-41 T 01-11-2018 IPR031100 LOG family MLA2C4_13115 c638d8f68849be915ef7fd50b8c847e6 431 Pfam PF00534 Glycosyl transferases group 1 221 346 1.2E-8 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_13115 c638d8f68849be915ef7fd50b8c847e6 431 Gene3D G3DSA:3.40.50.2000 103 198 2.0E-13 T 01-11-2018 MLA2C4_13115 c638d8f68849be915ef7fd50b8c847e6 431 Gene3D G3DSA:3.40.50.2000 199 340 2.0E-13 T 01-11-2018 MLA2C4_13115 c638d8f68849be915ef7fd50b8c847e6 431 SUPERFAMILY SSF53756 1 345 1.82E-14 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 1.3E-30 T 01-11-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 613 7.8E-24 T 01-11-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:3.90.1110.10 154 264 4.6E-7 T 01-11-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 6.5E-27 T 01-11-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 373 409 4.7E-6 T 01-11-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 ProSitePatterns PS01166 RNA polymerases beta chain signature. 921 933 - T 01-11-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:3.90.1100.10 20 153 3.7E-56 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:3.90.1800.10 1056 1108 1.1E-10 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:2.40.270.10 751 789 3.3E-6 T 01-11-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF04560 RNA polymerase Rpb2, domain 7 1070 1145 1.3E-27 T 01-11-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:2.40.50.150 790 929 2.8E-60 T 01-11-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 SUPERFAMILY SSF64484 13 1156 0.0 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:3.90.1100.10 600 670 1.3E-19 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:3.90.1100.10 389 589 4.6E-75 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1146 12.597 T 01-11-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF00562 RNA polymerase Rpb2, domain 6 675 1068 2.7E-162 T 01-11-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:2.40.270.10 981 1046 1.6E-24 T 01-11-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Gene3D G3DSA:2.40.50.100 671 750 4.8E-26 T 01-11-2018 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 Pfam PF04563 RNA polymerase beta subunit 28 453 5.6E-31 T 01-11-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_00630 4b491da8977c8e9624d66d347aa19ca1 1177 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 895 0.0 T 01-11-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_26060 2c0a7993a6343d7165ab47d887a6eec5 81 ProDom PD065427 YUSU IG COIL COILED BH3491 1 80 2.0E-40 T 01-11-2018 IPR020393 Uncharacterised protein family YusU MLA2C4_26060 2c0a7993a6343d7165ab47d887a6eec5 81 Pfam PF10835 Protein of unknown function (DUF2573) 3 80 6.2E-41 T 01-11-2018 IPR020393 Uncharacterised protein family YusU MLA2C4_06215 3c617ebb970ffb9d2b60f007b5cfb0af 543 PIRSF PIRSF002741 1 543 1.2E-104 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_06215 3c617ebb970ffb9d2b60f007b5cfb0af 543 Gene3D G3DSA:3.40.190.10 53 530 2.9E-177 T 01-11-2018 MLA2C4_06215 3c617ebb970ffb9d2b60f007b5cfb0af 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 464 3.2E-74 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_06215 3c617ebb970ffb9d2b60f007b5cfb0af 543 SUPERFAMILY SSF53850 36 538 3.8E-122 T 01-11-2018 MLA2C4_06215 3c617ebb970ffb9d2b60f007b5cfb0af 543 Gene3D G3DSA:3.90.76.10 72 194 2.9E-177 T 01-11-2018 MLA2C4_06215 3c617ebb970ffb9d2b60f007b5cfb0af 543 Gene3D G3DSA:3.10.105.10 294 514 2.9E-177 T 01-11-2018 MLA2C4_24105 64f3f17dec1e11816c027e495c180329 166 Pfam PF08534 Redoxin 19 159 8.8E-24 T 01-11-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MLA2C4_24105 64f3f17dec1e11816c027e495c180329 166 SUPERFAMILY SSF52833 3 160 2.62E-43 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_24105 64f3f17dec1e11816c027e495c180329 166 Gene3D G3DSA:3.40.30.10 1 165 1.4E-47 T 01-11-2018 MLA2C4_24105 64f3f17dec1e11816c027e495c180329 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 01-11-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 MLA2C4_24105 64f3f17dec1e11816c027e495c180329 166 Hamap MF_00269 Thiol peroxidase [tpx]. 3 163 38.429 T 01-11-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 SUPERFAMILY SSF53067 7 253 4.44E-72 T 01-11-2018 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 Gene3D G3DSA:3.30.420.40 5 251 2.4E-84 T 01-11-2018 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 SUPERFAMILY SSF53067 252 501 2.02E-69 T 01-11-2018 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 250 1.4E-70 T 01-11-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 Gene3D G3DSA:3.30.420.40 252 512 2.4E-89 T 01-11-2018 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 510 6.5E-198 T 01-11-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 454 1.2E-38 T 01-11-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MLA2C4_11355 0c6bf67063f9f7a5a02ea7543ae7fdac 512 PIRSF PIRSF000538 5 505 1.0E-151 T 01-11-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 Gene3D G3DSA:3.40.50.720 109 249 1.2E-39 T 01-11-2018 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 Pfam PF02254 TrkA-N domain 110 222 6.7E-34 T 01-11-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 Pfam PF02080 TrkA-C domain 257 326 1.9E-14 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 SUPERFAMILY SSF51735 106 244 1.83E-36 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 Pfam PF07885 Ion channel 12 86 1.1E-15 T 01-11-2018 IPR013099 Potassium channel domain MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 SUPERFAMILY SSF81324 4 129 2.62E-27 T 01-11-2018 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 Gene3D G3DSA:3.30.70.1450 253 329 1.9E-18 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 Gene3D G3DSA:1.10.287.70 1 108 3.2E-23 T 01-11-2018 MLA2C4_27950 b721f89797fb82943f26da317a90fe28 330 SUPERFAMILY SSF116726 251 326 4.45E-19 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 795 886 5.47E-7 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 1983 2073 2.04E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1841 1936 4.8E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 388 483 1.7E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 257 351 1.7E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1444 1539 2.3E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1048 1142 3.6E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 652 746 1.1E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 784 878 9.2E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 916 1010 7.8E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1973 2067 4.5E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 126 211 2.5E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 4 80 4.3E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 521 615 4.1E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1312 1408 6.2E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1180 1275 6.8E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1708 1793 1.0E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Pfam PF01345 Domain of unknown function DUF11 1577 1663 1.4E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 780 911 2.2E-8 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 1586 1677 9.69E-6 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 1719 1810 1.91E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 1301 1440 1.2E-6 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 1961 2115 9.4E-7 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 515 645 5.5E-5 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 1 114 2.4E-6 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 646 760 1.3E-5 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 1826 1960 1.4E-6 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 381 514 6.4E-8 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 250 380 8.2E-9 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 912 1046 2.5E-8 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 8 95 6.46E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 925 1018 3.73E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 138 228 1.19E-6 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 1570 1705 3.6E-7 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 1174 1300 1.1E-8 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 Gene3D G3DSA:2.60.40.740 122 249 8.9E-8 T 01-11-2018 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1709 1761 3.3E-22 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 389 440 1.2E-22 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 653 705 2.2E-23 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1313 1365 1.1E-22 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 917 968 1.0E-21 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1181 1232 9.0E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 521 572 7.4E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3 48 7.4E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 128 179 9.2E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1973 2025 1.3E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1049 1101 6.3E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1577 1628 3.1E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 785 837 1.1E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1841 1893 7.8E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 258 309 1.4E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1445 1496 2.9E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 268 359 1.59E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 663 752 7.45E-6 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19020 bddc51d85529a1352d62de00bd250fc4 2121 SUPERFAMILY SSF49401 526 621 6.21E-6 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_14270 a1763ad32998fece79350ffd4ca0ca7c 138 Pfam PF00583 Acetyltransferase (GNAT) family 28 116 1.1E-15 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14270 a1763ad32998fece79350ffd4ca0ca7c 138 Gene3D G3DSA:3.40.630.30 35 138 2.5E-29 T 01-11-2018 MLA2C4_14270 a1763ad32998fece79350ffd4ca0ca7c 138 SUPERFAMILY SSF55729 5 138 1.16E-31 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 Gene3D G3DSA:3.30.420.40 2 194 5.0E-77 T 01-11-2018 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PIRSF PIRSF000722 1 396 3.8E-154 T 01-11-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 SUPERFAMILY SSF53067 1 194 2.91E-74 T 01-11-2018 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 Pfam PF00871 Acetokinase family 3 388 3.7E-172 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 01-11-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 SUPERFAMILY SSF53067 156 393 2.5E-93 T 01-11-2018 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 393 6.6E-179 T 01-11-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 01-11-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PRINTS PR00471 Acetate kinase family signature 172 185 3.7E-47 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PRINTS PR00471 Acetate kinase family signature 202 223 3.7E-47 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PRINTS PR00471 Acetate kinase family signature 299 312 3.7E-47 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PRINTS PR00471 Acetate kinase family signature 321 337 3.7E-47 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PRINTS PR00471 Acetate kinase family signature 4 15 3.7E-47 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 PRINTS PR00471 Acetate kinase family signature 375 387 3.7E-47 T 01-11-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 197.354 T 01-11-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MLA2C4_24095 ad8e00af73d017de7ce4f4060ac92a18 397 Gene3D G3DSA:3.30.420.40 195 396 2.8E-81 T 01-11-2018 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 Gene3D G3DSA:1.20.1250.20 2 390 1.0E-34 T 01-11-2018 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 SUPERFAMILY SSF103473 3 391 7.98E-44 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 6 28 3.1E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 292 315 3.1E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 69 87 3.1E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 157 174 3.1E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 PRINTS PR01988 Putative bacilysin exporter bacE signature 130 151 3.1E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_08475 19f5ea46682067b7ddfae08f2f70c98a 406 Pfam PF07690 Major Facilitator Superfamily 8 351 6.8E-27 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_14655 a370161d53357155e9b3f8c9f8d3a070 112 Pfam PF07978 NIPSNAP 8 76 5.4E-7 T 01-11-2018 IPR012577 NIPSNAP MLA2C4_14655 a370161d53357155e9b3f8c9f8d3a070 112 SUPERFAMILY SSF54909 1 79 2.15E-10 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_14655 a370161d53357155e9b3f8c9f8d3a070 112 Gene3D G3DSA:3.30.70.100 1 101 6.5E-8 T 01-11-2018 MLA2C4_23755 bd115941304d5ecbc9e98918118487fe 163 PIRSF PIRSF030140 1 163 2.0E-59 T 01-11-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 MLA2C4_23755 bd115941304d5ecbc9e98918118487fe 163 Gene3D G3DSA:1.10.4010.10 1 163 8.6E-15 T 01-11-2018 MLA2C4_23755 bd115941304d5ecbc9e98918118487fe 163 Pfam PF08761 dUTPase 2 163 2.7E-52 T 01-11-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 MLA2C4_23755 bd115941304d5ecbc9e98918118487fe 163 SUPERFAMILY SSF101386 1 163 9.38E-49 T 01-11-2018 MLA2C4_24250 219a942f8f0a86eab81f9fec92185a87 137 Gene3D G3DSA:3.10.180.10 2 127 2.3E-12 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_24250 219a942f8f0a86eab81f9fec92185a87 137 SUPERFAMILY SSF54593 5 129 6.6E-14 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_02540 0d5202d8b0201bda5e4ceba7a8fd02a5 287 SMART SM00478 127 286 2.6E-11 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_02540 0d5202d8b0201bda5e4ceba7a8fd02a5 287 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 261 2.8E-15 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_02540 0d5202d8b0201bda5e4ceba7a8fd02a5 287 SUPERFAMILY SSF48150 113 284 1.24E-35 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MLA2C4_02540 0d5202d8b0201bda5e4ceba7a8fd02a5 287 Gene3D G3DSA:1.10.340.30 115 234 1.9E-46 T 01-11-2018 MLA2C4_02540 0d5202d8b0201bda5e4ceba7a8fd02a5 287 Gene3D G3DSA:1.10.1670.40 235 284 1.9E-46 T 01-11-2018 MLA2C4_04740 93bf71349d288afc8fbbbe5de89b1c70 807 SUPERFAMILY SSF49478 445 508 7.45E-10 T 01-11-2018 MLA2C4_04740 93bf71349d288afc8fbbbe5de89b1c70 807 Gene3D G3DSA:2.60.40.10 344 434 1.6E-22 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_04740 93bf71349d288afc8fbbbe5de89b1c70 807 Gene3D G3DSA:2.60.40.10 435 528 7.8E-21 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_04740 93bf71349d288afc8fbbbe5de89b1c70 807 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 50 331 1.8E-21 T 01-11-2018 IPR026588 Choice-of-anchor A domain MLA2C4_04740 93bf71349d288afc8fbbbe5de89b1c70 807 SUPERFAMILY SSF49478 355 422 1.49E-9 T 01-11-2018 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 PRINTS PR00113 Alkaline phosphatase signature 142 162 1.6E-32 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 PRINTS PR00113 Alkaline phosphatase signature 263 292 1.6E-32 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 PRINTS PR00113 Alkaline phosphatase signature 186 196 1.6E-32 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 PRINTS PR00113 Alkaline phosphatase signature 44 64 1.6E-32 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 Gene3D G3DSA:3.40.720.10 45 446 9.4E-126 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 SUPERFAMILY SSF53649 28 475 3.82E-117 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 Gene3D G3DSA:1.10.1200.140 381 443 9.4E-126 T 01-11-2018 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 SMART SM00098 45 469 2.9E-84 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_15790 1b4eee5b91b5eae10f72faaa722616e7 557 Pfam PF00245 Alkaline phosphatase 45 466 2.5E-91 T 01-11-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 Pfam PF00664 ABC transporter transmembrane region 72 298 4.5E-10 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 Gene3D G3DSA:3.40.50.300 347 597 1.7E-83 T 01-11-2018 MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 SUPERFAMILY SSF52540 346 594 1.55E-81 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 SUPERFAMILY SSF90123 23 323 3.53E-27 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 SMART SM00382 383 569 1.5E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 Pfam PF00005 ABC transporter 374 523 1.7E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19225 dc41b5efa1ded7ec1c94162146836d32 599 Gene3D G3DSA:1.20.1560.10 9 331 2.4E-21 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_10375 87ab510ca771da3310f80950817c44c2 313 Gene3D G3DSA:3.30.460.20 4 132 7.3E-26 T 01-11-2018 MLA2C4_10375 87ab510ca771da3310f80950817c44c2 313 SUPERFAMILY SSF144083 249 310 2.62E-15 T 01-11-2018 MLA2C4_10375 87ab510ca771da3310f80950817c44c2 313 Pfam PF01544 CorA-like Mg2+ transporter protein 21 311 3.2E-65 T 01-11-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MLA2C4_10375 87ab510ca771da3310f80950817c44c2 313 Gene3D G3DSA:1.20.58.340 133 255 5.3E-30 T 01-11-2018 MLA2C4_10375 87ab510ca771da3310f80950817c44c2 313 Gene3D G3DSA:1.20.58.340 257 313 4.3E-12 T 01-11-2018 MLA2C4_10375 87ab510ca771da3310f80950817c44c2 313 SUPERFAMILY SSF143865 1 248 5.75E-57 T 01-11-2018 MLA2C4_08075 5496ae29a7504c13daf39a407b4228dc 381 Gene3D G3DSA:3.40.50.2000 22 369 4.3E-140 T 01-11-2018 MLA2C4_08075 5496ae29a7504c13daf39a407b4228dc 381 Pfam PF00534 Glycosyl transferases group 1 187 349 1.8E-43 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_08075 5496ae29a7504c13daf39a407b4228dc 381 Gene3D G3DSA:3.40.50.2000 175 356 4.3E-140 T 01-11-2018 MLA2C4_08075 5496ae29a7504c13daf39a407b4228dc 381 SUPERFAMILY SSF53756 8 375 9.42E-93 T 01-11-2018 MLA2C4_08075 5496ae29a7504c13daf39a407b4228dc 381 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 373 2.9E-181 T 01-11-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 MLA2C4_08075 5496ae29a7504c13daf39a407b4228dc 381 Pfam PF13439 Glycosyltransferase Family 4 13 177 1.5E-25 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MLA2C4_22390 79fc9858db4dd74315119093ff223267 84 Pfam PF11116 Protein of unknown function (DUF2624) 1 82 4.0E-32 T 01-11-2018 IPR020277 Protein of unknown function DUF2624 MLA2C4_22390 79fc9858db4dd74315119093ff223267 84 ProDom PD060869 YQFT IG BH1387 1 68 1.0E-30 T 01-11-2018 IPR020277 Protein of unknown function DUF2624 MLA2C4_11635 94bf859518fafed7f2cf325be9660bff 322 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 214 271 5.4E-16 T 01-11-2018 IPR006343 DnaD domain MLA2C4_11635 94bf859518fafed7f2cf325be9660bff 322 Pfam PF07261 Replication initiation and membrane attachment 214 273 4.5E-11 T 01-11-2018 IPR006343 DnaD domain MLA2C4_11635 94bf859518fafed7f2cf325be9660bff 322 Gene3D G3DSA:1.10.10.630 203 272 1.1E-11 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_11635 94bf859518fafed7f2cf325be9660bff 322 SUPERFAMILY SSF158499 209 267 2.48E-12 T 01-11-2018 IPR034829 DnaD-like domain superfamily MLA2C4_13320 c8d6c4b417a9ace05863efa62b3bfbad 378 Pfam PF01757 Acyltransferase family 19 359 4.0E-35 T 01-11-2018 IPR002656 Acyltransferase 3 GO:0016747 MLA2C4_18480 4bc4bf96154f4ade573f81da32a50a58 82 Pfam PF06961 Protein of unknown function (DUF1294) 10 64 8.6E-27 T 01-11-2018 IPR010718 Protein of unknown function DUF1294 MLA2C4_18480 4bc4bf96154f4ade573f81da32a50a58 82 PIRSF PIRSF002599 2 81 1.3E-11 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_00275 81c42d38392e09b446576aa9242ccc05 97 SUPERFAMILY SSF160537 1 86 1.23E-33 T 01-11-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 MLA2C4_00275 81c42d38392e09b446576aa9242ccc05 97 Pfam PF04026 SpoVG 1 81 3.3E-36 T 01-11-2018 IPR007170 Stage V sporulation protein G GO:0030435 MLA2C4_00275 81c42d38392e09b446576aa9242ccc05 97 Gene3D G3DSA:3.30.1120.40 1 97 7.4E-40 T 01-11-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 MLA2C4_00275 81c42d38392e09b446576aa9242ccc05 97 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 95 28.389 T 01-11-2018 IPR007170 Stage V sporulation protein G GO:0030435 MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 PIRSF PIRSF000441 1 218 3.7E-87 T 01-11-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 Gene3D G3DSA:1.10.3130.10 1 66 2.1E-25 T 01-11-2018 MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 6.3E-80 T 01-11-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 Gene3D G3DSA:2.160.10.10 67 183 2.4E-37 T 01-11-2018 MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.4E-4 T 01-11-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 2.8E-6 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.0E-8 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 SUPERFAMILY SSF51161 2 168 1.8E-57 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_00560 9f5f945d7ec04d899908b30920c70b72 221 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_20505 47945022c55090b7a638ce5b68caddaa 166 Pfam PF02620 Uncharacterized ACR, COG1399 56 163 5.2E-22 T 01-11-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 Pfam PF01472 PUA domain 277 348 6.9E-21 T 01-11-2018 IPR002478 PUA domain GO:0003723 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 Gene3D G3DSA:2.30.130.10 266 366 1.4E-27 T 01-11-2018 IPR036974 PUA domain superfamily GO:0003723 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 Pfam PF00696 Amino acid kinase family 4 232 1.7E-40 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 Gene3D G3DSA:3.40.1160.10 1 263 1.0E-76 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 1.2E-50 T 01-11-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 1.2E-50 T 01-11-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 1.2E-50 T 01-11-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 1.2E-50 T 01-11-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 1.2E-50 T 01-11-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 SUPERFAMILY SSF53633 4 254 1.27E-62 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 PIRSF PIRSF000729 1 367 2.4E-144 T 01-11-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 365 2.8E-135 T 01-11-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 SMART SM00359 277 357 5.0E-17 T 01-11-2018 IPR002478 PUA domain GO:0003723 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 260 35.712 T 01-11-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MLA2C4_15740 b00ae2402700026028faf8a65cef1b48 367 SUPERFAMILY SSF88697 277 365 1.49E-19 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_03035 67d8702881a5327b87ae25e6101b6cd0 234 SUPERFAMILY SSF56300 3 215 7.18E-39 T 01-11-2018 MLA2C4_03035 67d8702881a5327b87ae25e6101b6cd0 234 Gene3D G3DSA:3.60.21.10 1 234 8.1E-60 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_03035 67d8702881a5327b87ae25e6101b6cd0 234 Pfam PF00149 Calcineurin-like phosphoesterase 3 207 7.8E-17 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 Gene3D G3DSA:3.90.1230.10 193 298 1.2E-147 T 01-11-2018 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 SUPERFAMILY SSF56512 3 355 1.28E-166 T 01-11-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 PIRSF PIRSF037219 1 356 2.6E-190 T 01-11-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 Gene3D G3DSA:3.90.340.10 6 353 1.2E-147 T 01-11-2018 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 Pfam PF02898 Nitric oxide synthase, oxygenase domain 4 355 3.8E-164 T 01-11-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 Gene3D G3DSA:3.90.440.10 82 192 1.2E-147 T 01-11-2018 MLA2C4_28200 d6d51881bc8047bd7b5a9ccf68a9c72c 356 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 65 72 - T 01-11-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 303 3.2E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 Gene3D G3DSA:1.20.1480.50 147 238 1.4E-16 T 01-11-2018 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 SUPERFAMILY SSF55874 307 452 1.44E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 Gene3D G3DSA:1.10.287.130 239 305 4.8E-12 T 01-11-2018 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 SMART SM00387 349 457 1.6E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 SMART SM00388 243 305 3.9E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 Pfam PF00672 HAMP domain 185 232 9.1E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.6E-5 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.6E-5 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 SUPERFAMILY SSF158472 185 233 1.44E-8 T 01-11-2018 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 SMART SM00304 184 235 6.7E-9 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 SUPERFAMILY SSF47384 228 304 1.02E-13 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 441 1.5E-14 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_15135 c99e0c2301e1f5c4a55f8e2855e8e31b 458 Gene3D G3DSA:3.30.565.10 307 458 6.4E-30 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_20575 dc5335af0abd510a2a9e2bf0c77593f4 121 Gene3D G3DSA:3.30.310.100 1 121 2.4E-46 T 01-11-2018 IPR036491 YugN-like superfamily MLA2C4_20575 dc5335af0abd510a2a9e2bf0c77593f4 121 SUPERFAMILY SSF160755 1 114 6.02E-39 T 01-11-2018 IPR036491 YugN-like superfamily MLA2C4_20575 dc5335af0abd510a2a9e2bf0c77593f4 121 Pfam PF08868 YugN-like family 6 90 1.7E-13 T 01-11-2018 IPR014967 Uncharacterised protein family, YugN-like MLA2C4_04605 b4659f3832326914a32f69b6689d42b0 418 SUPERFAMILY SSF103473 8 401 4.01E-48 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_04605 b4659f3832326914a32f69b6689d42b0 418 Pfam PF07690 Major Facilitator Superfamily 267 402 2.2E-12 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_04605 b4659f3832326914a32f69b6689d42b0 418 Pfam PF07690 Major Facilitator Superfamily 15 244 8.5E-27 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_04605 b4659f3832326914a32f69b6689d42b0 418 Gene3D G3DSA:1.20.1250.20 6 405 6.2E-45 T 01-11-2018 MLA2C4_21800 7a31640f93d5c8310aa43bef30db9585 77 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 1.1E-29 T 01-11-2018 IPR020138 Uncharacterised protein family YqzF MLA2C4_21800 7a31640f93d5c8310aa43bef30db9585 77 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 7.0E-33 T 01-11-2018 IPR020138 Uncharacterised protein family YqzF MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Gene3D G3DSA:1.10.1040.10 208 333 2.0E-18 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Gene3D G3DSA:1.10.1040.10 359 472 1.4E-7 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Gene3D G3DSA:3.40.50.720 1 207 6.0E-66 T 01-11-2018 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 SUPERFAMILY SSF48179 356 458 1.36E-19 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Pfam PF00378 Enoyl-CoA hydratase/isomerase 489 621 1.2E-11 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 204 9.3E-44 T 01-11-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 SUPERFAMILY SSF48179 205 324 1.11E-20 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 207 304 9.5E-10 T 01-11-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 SUPERFAMILY SSF51735 1 205 1.22E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 SUPERFAMILY SSF52096 482 790 2.84E-38 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_26040 8b962045917b1bff4f7d7e313128d69b 793 Gene3D G3DSA:3.90.226.10 484 670 4.7E-28 T 01-11-2018 MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 425 2.0E-200 T 01-11-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 Pfam PF00202 Aminotransferase class-III 35 394 2.0E-76 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 SUPERFAMILY SSF53383 4 426 1.35E-131 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 Gene3D G3DSA:3.40.640.10 72 319 5.0E-184 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 Gene3D G3DSA:3.90.1150.10 10 421 5.0E-184 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_23255 7db78c27d1098eeb925bcdeaac0cf0f0 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 106.465 T 01-11-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 Gene3D G3DSA:3.40.190.10 134 341 4.0E-112 T 01-11-2018 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 Pfam PF13416 Bacterial extracellular solute-binding protein 45 311 4.5E-43 T 01-11-2018 IPR006059 Bacterial extracellular solute-binding protein MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 Gene3D G3DSA:3.40.190.10 32 311 4.0E-112 T 01-11-2018 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PIRSF PIRSF019574 1 348 7.2E-108 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 91 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 293 319 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 50 71 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 106 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 2.0E-49 T 01-11-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MLA2C4_06855 e3af04aa1e4f9299aa9981faff4b9d1c 349 SUPERFAMILY SSF53850 28 345 2.17E-90 T 01-11-2018 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 Pfam PF13181 Tetratricopeptide repeat 141 170 0.0039 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 Pfam PF13414 TPR repeat 49 82 3.9E-8 T 01-11-2018 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 Gene3D G3DSA:1.25.40.10 23 210 4.2E-52 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SMART SM00028 35 68 0.0021 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SMART SM00028 103 136 0.62 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SMART SM00028 69 102 0.024 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SMART SM00028 137 170 0.061 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SMART SM00028 171 204 3.3E-6 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SMART SM00028 1 34 15.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 Pfam PF07719 Tetratricopeptide repeat 8 34 1.4E-5 T 01-11-2018 IPR013105 Tetratricopeptide repeat 2 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 Pfam PF13176 Tetratricopeptide repeat 108 138 0.024 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 SUPERFAMILY SSF48452 8 212 1.18E-40 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_22925 64e87cc1502a91550f9e7bb669e41279 219 Pfam PF00515 Tetratricopeptide repeat 171 204 8.9E-8 T 01-11-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 MLA2C4_25810 f5f4c20c63a64ebdb4a0a445f4939385 210 Pfam PF01022 Bacterial regulatory protein, arsR family 10 52 2.3E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_25810 f5f4c20c63a64ebdb4a0a445f4939385 210 Gene3D G3DSA:1.10.10.10 4 89 3.2E-14 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25810 f5f4c20c63a64ebdb4a0a445f4939385 210 SUPERFAMILY SSF46785 7 188 1.33E-34 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_09235 342f152a2e32ca4d57f3cb2486eba361 470 Gene3D G3DSA:1.10.530.10 246 361 5.9E-18 T 01-11-2018 MLA2C4_09235 342f152a2e32ca4d57f3cb2486eba361 470 Pfam PF00395 S-layer homology domain 151 194 1.2E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_09235 342f152a2e32ca4d57f3cb2486eba361 470 Pfam PF00395 S-layer homology domain 31 73 2.4E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_09235 342f152a2e32ca4d57f3cb2486eba361 470 Pfam PF00395 S-layer homology domain 91 134 1.0E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_09235 342f152a2e32ca4d57f3cb2486eba361 470 SMART SM00047 236 363 6.3E-6 T 01-11-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MLA2C4_09235 342f152a2e32ca4d57f3cb2486eba361 470 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 249 360 4.0E-18 T 01-11-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MLA2C4_16175 152a215692976a37e81abdbcaf978d27 253 Pfam PF03746 LamB/YcsF family 4 242 4.0E-105 T 01-11-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MLA2C4_16175 152a215692976a37e81abdbcaf978d27 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 247 47.711 T 01-11-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MLA2C4_16175 152a215692976a37e81abdbcaf978d27 253 SUPERFAMILY SSF88713 4 251 2.67E-102 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_16175 152a215692976a37e81abdbcaf978d27 253 Gene3D G3DSA:3.20.20.370 3 253 2.8E-106 T 01-11-2018 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Pfam PF01434 Peptidase family M41 392 601 2.3E-87 T 01-11-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 SUPERFAMILY SSF140990 412 603 7.46E-73 T 01-11-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Gene3D G3DSA:1.10.8.60 332 409 3.8E-30 T 01-11-2018 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Pfam PF06480 FtsH Extracellular 9 103 4.1E-12 T 01-11-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 602 5.6E-247 T 01-11-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 SUPERFAMILY SSF52540 154 402 7.57E-75 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 330 3.5E-46 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Gene3D G3DSA:3.40.50.300 148 331 1.1E-71 T 01-11-2018 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 01-11-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Gene3D G3DSA:1.20.58.760 412 610 6.3E-75 T 01-11-2018 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 610 38.772 T 01-11-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MLA2C4_00370 1c64d8748ab15c5fdbdbe88d60a4076b 633 SMART SM00382 194 333 3.6E-26 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 SUPERFAMILY SSF48179 182 328 6.46E-71 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 176 6.0E-77 T 01-11-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 Gene3D G3DSA:1.10.3730.40 181 335 1.5E-71 T 01-11-2018 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 SUPERFAMILY SSF51735 1 181 2.6E-73 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 325 6.2E-141 T 01-11-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 PIRSF PIRSF000116 2 204 3.0E-43 T 01-11-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 PIRSF PIRSF000116 200 330 8.8E-15 T 01-11-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 Gene3D G3DSA:3.40.50.720 1 180 2.1E-79 T 01-11-2018 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 327 44.685 T 01-11-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_09455 f720206dc7093c7ef7c49d51d3ab8846 335 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 182 325 4.5E-67 T 01-11-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MLA2C4_22875 fe0831f529ab518afbb80cb24f845182 92 Pfam PF06949 Protein of unknown function (DUF1292) 11 87 1.9E-16 T 01-11-2018 IPR009711 Uncharacterised protein family UPF0473 MLA2C4_22875 fe0831f529ab518afbb80cb24f845182 92 Hamap MF_01448 UPF0473 protein . 2 88 19.409 T 01-11-2018 IPR009711 Uncharacterised protein family UPF0473 MLA2C4_13730 8572117279e2395b25fb4e5fcc454234 563 Gene3D G3DSA:1.10.1370.30 7 562 2.1E-154 T 01-11-2018 MLA2C4_13730 8572117279e2395b25fb4e5fcc454234 563 Pfam PF01432 Peptidase family M3 163 549 6.6E-44 T 01-11-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MLA2C4_13730 8572117279e2395b25fb4e5fcc454234 563 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 560 2.7E-216 T 01-11-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related MLA2C4_13730 8572117279e2395b25fb4e5fcc454234 563 SUPERFAMILY SSF55486 32 550 9.04E-83 T 01-11-2018 MLA2C4_03635 f914f603639652a1cccb82713d50381b 433 Pfam PF05525 Branched-chain amino acid transport protein 6 426 6.0E-141 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_03635 f914f603639652a1cccb82713d50381b 433 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 414 1.2E-124 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_10075 7c279b9156c0bf3e9c73e2e6a86fd4b1 602 Gene3D G3DSA:1.10.510.40 407 551 1.9E-12 T 01-11-2018 MLA2C4_10075 7c279b9156c0bf3e9c73e2e6a86fd4b1 602 Pfam PF04183 IucA / IucC family 153 387 1.9E-53 T 01-11-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 MLA2C4_10075 7c279b9156c0bf3e9c73e2e6a86fd4b1 602 Pfam PF06276 Ferric iron reductase FhuF-like transporter 419 578 8.2E-40 T 01-11-2018 IPR022770 Ferric iron reductase FhuF domain MLA2C4_01410 0d1838222a5a64e36dfbc23cb624b56c 316 Gene3D G3DSA:2.50.20.10 2 195 2.2E-11 T 01-11-2018 MLA2C4_01410 0d1838222a5a64e36dfbc23cb624b56c 316 SUPERFAMILY SSF89392 7 184 1.22E-16 T 01-11-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MLA2C4_07065 b7ac177b8c3d3e43387e20ccd2b6fc02 207 SUPERFAMILY SSF54631 2 124 2.53E-20 T 01-11-2018 MLA2C4_07065 b7ac177b8c3d3e43387e20ccd2b6fc02 207 PIRSF PIRSF035040 1 207 1.5E-89 T 01-11-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type MLA2C4_07065 b7ac177b8c3d3e43387e20ccd2b6fc02 207 Pfam PF00571 CBS domain 13 59 1.3E-5 T 01-11-2018 IPR000644 CBS domain MLA2C4_07065 b7ac177b8c3d3e43387e20ccd2b6fc02 207 Gene3D G3DSA:3.10.580.10 1 127 5.9E-21 T 01-11-2018 MLA2C4_19940 86f7f133c7d631bfdd451c53748c37a7 103 Gene3D G3DSA:3.30.1330.30 1 98 1.5E-37 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_19940 86f7f133c7d631bfdd451c53748c37a7 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 93 9.7E-17 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 MLA2C4_19940 86f7f133c7d631bfdd451c53748c37a7 103 SUPERFAMILY SSF55315 3 98 3.26E-26 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_02905 0497460e085d54dcc13745327ecf75df 216 Gene3D G3DSA:3.40.30.10 28 216 3.7E-50 T 01-11-2018 MLA2C4_02905 0497460e085d54dcc13745327ecf75df 216 Pfam PF13462 Thioredoxin 44 212 2.1E-36 T 01-11-2018 IPR012336 Thioredoxin-like fold MLA2C4_02905 0497460e085d54dcc13745327ecf75df 216 SUPERFAMILY SSF52833 41 211 2.74E-35 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_20640 b3aeb93aab0c42221b668c132f6426ca 442 Gene3D G3DSA:3.40.50.300 231 441 4.5E-69 T 01-11-2018 MLA2C4_20640 b3aeb93aab0c42221b668c132f6426ca 442 Pfam PF13638 PIN domain 5 147 3.6E-32 T 01-11-2018 IPR002716 PIN domain MLA2C4_20640 b3aeb93aab0c42221b668c132f6426ca 442 Pfam PF02562 PhoH-like protein 233 437 5.3E-53 T 01-11-2018 IPR003714 PhoH-like protein GO:0005524 MLA2C4_20640 b3aeb93aab0c42221b668c132f6426ca 442 SUPERFAMILY SSF52540 26 420 3.82E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20640 b3aeb93aab0c42221b668c132f6426ca 442 Gene3D G3DSA:3.40.50.1010 2 149 8.7E-20 T 01-11-2018 MLA2C4_20640 b3aeb93aab0c42221b668c132f6426ca 442 SMART SM00670 3 135 4.8E-18 T 01-11-2018 IPR002716 PIN domain MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 Gene3D G3DSA:3.90.1150.150 279 362 1.0E-108 T 01-11-2018 MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 300 8.7E-75 T 01-11-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 Gene3D G3DSA:3.40.640.10 48 278 1.0E-108 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 397 453 5.4E-13 T 01-11-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 SUPERFAMILY SSF55904 331 464 3.01E-27 T 01-11-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 Gene3D G3DSA:3.90.100.10 372 471 4.3E-21 T 01-11-2018 MLA2C4_00180 15f3d1795eaf8f433afb9eba9f709cd7 473 SUPERFAMILY SSF53383 7 362 1.9E-81 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_10485 295d7f13f954c2b783d987dede149e4f 148 PRINTS PR00502 NUDIX hydrolase family signature 36 50 5.8E-6 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_10485 295d7f13f954c2b783d987dede149e4f 148 PRINTS PR00502 NUDIX hydrolase family signature 50 65 5.8E-6 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_10485 295d7f13f954c2b783d987dede149e4f 148 Pfam PF00293 NUDIX domain 6 139 1.4E-15 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_10485 295d7f13f954c2b783d987dede149e4f 148 SUPERFAMILY SSF55811 8 132 2.98E-17 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_10485 295d7f13f954c2b783d987dede149e4f 148 Gene3D G3DSA:3.90.79.10 2 139 3.2E-17 T 01-11-2018 MLA2C4_10485 295d7f13f954c2b783d987dede149e4f 148 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_06575 2d605d54b4bdd73049f7a68837954aea 513 SUPERFAMILY SSF55469 314 506 8.7E-10 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_06575 2d605d54b4bdd73049f7a68837954aea 513 Pfam PF00881 Nitroreductase family 410 499 4.0E-8 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_06575 2d605d54b4bdd73049f7a68837954aea 513 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 59 227 4.7E-54 T 01-11-2018 IPR020051 SagB-type dehydrogenase domain MLA2C4_06575 2d605d54b4bdd73049f7a68837954aea 513 Gene3D G3DSA:3.40.109.10 285 502 3.6E-23 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_06575 2d605d54b4bdd73049f7a68837954aea 513 Gene3D G3DSA:3.40.109.10 22 284 3.6E-52 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_17265 355cce4fb59690d0dcd0caeae5d15652 301 Pfam PF13732 Domain of unknown function (DUF4162) 212 298 3.1E-7 T 01-11-2018 IPR025302 Domain of unknown function DUF4162 MLA2C4_17265 355cce4fb59690d0dcd0caeae5d15652 301 SMART SM00382 27 205 3.4E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17265 355cce4fb59690d0dcd0caeae5d15652 301 Pfam PF00005 ABC transporter 19 157 2.1E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17265 355cce4fb59690d0dcd0caeae5d15652 301 SUPERFAMILY SSF52540 3 219 1.81E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17265 355cce4fb59690d0dcd0caeae5d15652 301 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17265 355cce4fb59690d0dcd0caeae5d15652 301 Gene3D G3DSA:3.40.50.300 1 233 4.2E-66 T 01-11-2018 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 Pfam PF12833 Helix-turn-helix domain 326 404 3.0E-21 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 357 399 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 SUPERFAMILY SSF46689 306 354 4.48E-7 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 SMART SM00342 320 403 1.8E-31 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 SUPERFAMILY SSF46689 357 406 2.91E-13 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 Gene3D G3DSA:1.10.10.60 301 353 6.3E-16 T 01-11-2018 MLA2C4_16390 a1d5558275de4cc46826e3052c80f4a0 409 Gene3D G3DSA:1.10.10.60 354 407 4.9E-18 T 01-11-2018 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 107 130 - T 01-11-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 489 3.2E-158 T 01-11-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 SUPERFAMILY SSF53623 100 333 1.96E-68 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Gene3D G3DSA:3.90.190.20 339 492 9.2E-64 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 421 1.3E-23 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Pfam PF01225 Mur ligase family, catalytic domain 22 84 2.0E-6 T 01-11-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 SUPERFAMILY SSF63418 3 100 3.92E-21 T 01-11-2018 IPR035911 MurE/MurF, N-terminal MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Gene3D G3DSA:3.40.1190.10 100 338 2.2E-85 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 489 35.25 T 01-11-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Pfam PF08245 Mur ligase middle domain 109 315 4.3E-54 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 SUPERFAMILY SSF53244 335 490 2.75E-51 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_13775 50a09842c159e2f237362ed24042a3bc 493 Gene3D G3DSA:3.40.1390.10 2 98 1.4E-27 T 01-11-2018 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 SUPERFAMILY SSF51569 1 212 4.5E-78 T 01-11-2018 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 01-11-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 Hamap MF_00494 Probable transaldolase [tal]. 1 214 48.361 T 01-11-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 211 2.0E-55 T 01-11-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 01-11-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 Gene3D G3DSA:3.20.20.70 1 215 1.3E-89 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_03535 50a42ae7fb0ab484f66adbaac425ef3c 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 2.8E-102 T 01-11-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MLA2C4_14830 a5346b861217fd48415103b2b9f4fd25 461 Pfam PF00395 S-layer homology domain 28 70 5.2E-14 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_14830 a5346b861217fd48415103b2b9f4fd25 461 Pfam PF00395 S-layer homology domain 146 189 2.2E-15 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_14830 a5346b861217fd48415103b2b9f4fd25 461 SUPERFAMILY SSF56281 207 459 4.72E-55 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_14830 a5346b861217fd48415103b2b9f4fd25 461 Pfam PF00753 Metallo-beta-lactamase superfamily 218 414 1.9E-15 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_14830 a5346b861217fd48415103b2b9f4fd25 461 Gene3D G3DSA:3.60.15.10 208 458 1.4E-73 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_14830 a5346b861217fd48415103b2b9f4fd25 461 SMART SM00849 220 415 7.0E-8 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_00310 268f69f7aad6befa751124d3afccd92b 533 PIRSF PIRSF038958 4 526 3.8E-86 T 01-11-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type MLA2C4_00310 268f69f7aad6befa751124d3afccd92b 533 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 510 1.3E-28 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MLA2C4_00310 268f69f7aad6befa751124d3afccd92b 533 Pfam PF01943 Polysaccharide biosynthesis protein 9 307 4.1E-39 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 SUPERFAMILY SSF48029 115 326 3.01E-48 T 01-11-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 Pfam PF01706 FliG C-terminal domain 218 324 7.3E-30 T 01-11-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 114 137 2.4E-41 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 195 220 2.4E-41 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 5 21 2.4E-41 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 226 246 2.4E-41 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 273 299 2.4E-41 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 34 60 2.4E-41 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 Gene3D G3DSA:1.10.220.30 2 87 3.7E-17 T 01-11-2018 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 Gene3D G3DSA:1.10.220.30 102 194 7.2E-22 T 01-11-2018 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 2 333 1.0E-67 T 01-11-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 Pfam PF14841 FliG middle domain 118 186 2.6E-18 T 01-11-2018 IPR032779 Flagellar motor switch protein FliG, middle domain MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 Pfam PF14842 FliG N-terminal domain 5 101 2.5E-17 T 01-11-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 Gene3D G3DSA:1.10.220.30 196 334 2.1E-35 T 01-11-2018 MLA2C4_08615 7abc3023cb87e2b4b2a309ce2d0a8597 334 SUPERFAMILY SSF48029 8 112 7.32E-16 T 01-11-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MLA2C4_10165 ac6deec5b46ed1311772f887c688897c 272 Gene3D G3DSA:3.40.50.620 1 272 3.5E-90 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_10165 ac6deec5b46ed1311772f887c688897c 272 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 266 49.263 T 01-11-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 MLA2C4_10165 ac6deec5b46ed1311772f887c688897c 272 Pfam PF02540 NAD synthase 23 263 4.6E-76 T 01-11-2018 IPR022310 NAD/GMP synthase MLA2C4_10165 ac6deec5b46ed1311772f887c688897c 272 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 272 3.5E-81 T 01-11-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MLA2C4_10165 ac6deec5b46ed1311772f887c688897c 272 SUPERFAMILY SSF52402 3 271 3.93E-82 T 01-11-2018 MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 SUPERFAMILY SSF64182 1 307 1.01E-87 T 01-11-2018 IPR038763 DHH phosphoesterase superfamily MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 Gene3D G3DSA:3.10.310.20 190 309 1.0E-37 T 01-11-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 Gene3D G3DSA:3.90.1640.10 1 188 9.3E-83 T 01-11-2018 MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 Pfam PF02833 DHHA2 domain 183 306 6.4E-22 T 01-11-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 Pfam PF01368 DHH family 3 146 1.3E-31 T 01-11-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 SMART SM01131 181 307 9.1E-54 T 01-11-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_14940 839976c3fc213e4c85c30f0d7c303c1a 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 46.699 T 01-11-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MLA2C4_06255 59038877d1194df950fb301fd0153a94 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.166 T 01-11-2018 IPR023731 Regulatory protein Spx GO:0045892 MLA2C4_06255 59038877d1194df950fb301fd0153a94 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 8.9E-35 T 01-11-2018 IPR006504 Transcriptional regulator Spx/MgsR MLA2C4_06255 59038877d1194df950fb301fd0153a94 131 SUPERFAMILY SSF52833 1 129 3.3E-38 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_06255 59038877d1194df950fb301fd0153a94 131 Pfam PF03960 ArsC family 5 113 9.4E-21 T 01-11-2018 IPR006660 Arsenate reductase-like MLA2C4_06255 59038877d1194df950fb301fd0153a94 131 Gene3D G3DSA:3.40.30.10 1 131 6.4E-45 T 01-11-2018 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 Pfam PF04542 Sigma-70 region 2 18 81 9.7E-13 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 SUPERFAMILY SSF88659 102 169 5.89E-14 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 Pfam PF08281 Sigma-70, region 4 114 164 3.1E-14 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 Gene3D G3DSA:1.10.1740.10 3 80 2.2E-20 T 01-11-2018 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 39 70 - T 01-11-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 167 6.0E-31 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 SUPERFAMILY SSF88946 10 92 5.89E-19 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_13335 edbfd1511a9bde779c6ef6484fad743e 177 Gene3D G3DSA:1.10.10.10 93 171 1.9E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Pfam PF00989 PAS fold 271 319 6.6E-8 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SUPERFAMILY SSF158472 211 259 2.09E-10 T 01-11-2018 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SUPERFAMILY SSF55785 257 374 2.62E-11 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Gene3D G3DSA:1.10.287.130 208 280 1.7E-11 T 01-11-2018 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SMART SM00304 210 262 2.9E-12 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 495 604 6.2E-29 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SUPERFAMILY SSF47384 368 448 1.2E-19 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Gene3D G3DSA:3.30.450.20 281 373 5.4E-22 T 01-11-2018 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Gene3D G3DSA:1.10.287.130 374 453 3.8E-29 T 01-11-2018 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SMART SM00387 494 606 4.9E-42 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Gene3D G3DSA:3.30.565.10 454 612 3.5E-49 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Pfam PF00512 His Kinase A (phospho-acceptor) domain 383 448 6.9E-18 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 1.1E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 545 1.1E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 1.1E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 559 1.1E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 382 1.6E-6 T 01-11-2018 IPR000014 PAS domain MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Pfam PF00672 HAMP domain 211 259 1.8E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SUPERFAMILY SSF55874 438 608 3.89E-49 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SMART SM00388 382 449 6.2E-20 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 SMART SM00091 269 335 6.2E-7 T 01-11-2018 IPR000014 PAS domain MLA2C4_28345 89b819683281a1ab4d39e3da08485351 613 Gene3D G3DSA:3.30.450.20 32 188 2.6E-39 T 01-11-2018 MLA2C4_14965 8fe4ead9bd77f4a0a9e3229e4dc5acb8 121 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 110 3.5E-20 T 01-11-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MLA2C4_14965 8fe4ead9bd77f4a0a9e3229e4dc5acb8 121 SUPERFAMILY SSF69118 9 116 2.49E-27 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_14965 8fe4ead9bd77f4a0a9e3229e4dc5acb8 121 Gene3D G3DSA:1.20.1290.10 1 117 7.1E-28 T 01-11-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MLA2C4_09290 74cc0509aa4ba16914cb47784dc271ce 395 Gene3D G3DSA:3.40.50.10490 2 199 4.4E-56 T 01-11-2018 MLA2C4_09290 74cc0509aa4ba16914cb47784dc271ce 395 Gene3D G3DSA:3.40.50.10490 206 385 1.2E-66 T 01-11-2018 MLA2C4_09290 74cc0509aa4ba16914cb47784dc271ce 395 SUPERFAMILY SSF53697 17 381 6.34E-52 T 01-11-2018 MLA2C4_09290 74cc0509aa4ba16914cb47784dc271ce 395 Pfam PF01380 SIS domain 56 192 4.3E-11 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_09290 74cc0509aa4ba16914cb47784dc271ce 395 Pfam PF01380 SIS domain 232 340 1.2E-8 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_07825 7134f30b88ed6bde32a2628b61069dec 187 Pfam PF02517 CAAX protease self-immunity 97 179 3.8E-11 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_12025 c0ac0fcd64fdef5c734ca92e6f7c6818 335 Pfam PF01183 Glycosyl hydrolases family 25 5 168 5.5E-21 T 01-11-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 MLA2C4_12025 c0ac0fcd64fdef5c734ca92e6f7c6818 335 Gene3D G3DSA:3.20.20.80 2 191 3.6E-69 T 01-11-2018 MLA2C4_12025 c0ac0fcd64fdef5c734ca92e6f7c6818 335 SUPERFAMILY SSF51445 4 187 1.21E-38 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_10450 892d4ab95cdb3ced7f5c352ad56ac9fb 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 8.3E-47 T 01-11-2018 IPR008231 Probable chaperone CsaA MLA2C4_10450 892d4ab95cdb3ced7f5c352ad56ac9fb 109 SUPERFAMILY SSF50249 2 108 7.71E-30 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_10450 892d4ab95cdb3ced7f5c352ad56ac9fb 109 Pfam PF01588 Putative tRNA binding domain 12 107 5.2E-15 T 01-11-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MLA2C4_10450 892d4ab95cdb3ced7f5c352ad56ac9fb 109 Gene3D G3DSA:2.40.50.140 1 109 1.9E-28 T 01-11-2018 MLA2C4_06040 cdcab48a8b13bfbd3d7f972d155f41e1 300 Gene3D G3DSA:3.90.850.10 86 300 3.7E-87 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MLA2C4_06040 cdcab48a8b13bfbd3d7f972d155f41e1 300 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 92 299 2.6E-70 T 01-11-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MLA2C4_06040 cdcab48a8b13bfbd3d7f972d155f41e1 300 SUPERFAMILY SSF56529 80 299 5.63E-75 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MLA2C4_07045 3456b0ed483a19fe3ca9931c45220e5e 394 Gene3D G3DSA:3.40.50.720 1 109 1.7E-8 T 01-11-2018 MLA2C4_07045 3456b0ed483a19fe3ca9931c45220e5e 394 SUPERFAMILY SSF51735 2 157 7.9E-13 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07045 3456b0ed483a19fe3ca9931c45220e5e 394 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 125 378 9.5E-20 T 01-11-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 MLA2C4_07045 3456b0ed483a19fe3ca9931c45220e5e 394 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 110 9.4E-14 T 01-11-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MLA2C4_07045 3456b0ed483a19fe3ca9931c45220e5e 394 Gene3D G3DSA:3.40.50.720 324 393 3.6E-9 T 01-11-2018 MLA2C4_07045 3456b0ed483a19fe3ca9931c45220e5e 394 Gene3D G3DSA:3.30.360.10 127 317 1.0E-40 T 01-11-2018 MLA2C4_09535 65c73ad55fda0c8e51b7ba5bf3ffe66d 462 Gene3D G3DSA:3.40.50.1820 171 436 1.2E-33 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09535 65c73ad55fda0c8e51b7ba5bf3ffe66d 462 SUPERFAMILY SSF53474 149 459 7.28E-32 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09535 65c73ad55fda0c8e51b7ba5bf3ffe66d 462 Pfam PF12697 Alpha/beta hydrolase family 194 426 4.7E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_26430 8961993d5cb1733fc75984ad48b7e03a 397 SUPERFAMILY SSF103473 1 394 3.53E-46 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_26430 8961993d5cb1733fc75984ad48b7e03a 397 Gene3D G3DSA:1.20.1250.20 2 393 4.6E-42 T 01-11-2018 MLA2C4_26430 8961993d5cb1733fc75984ad48b7e03a 397 Pfam PF07690 Major Facilitator Superfamily 14 358 2.3E-34 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 SUPERFAMILY SSF50677 202 392 1.26E-65 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 SUPERFAMILY SSF52374 1 639 3.9E-156 T 01-11-2018 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Gene3D G3DSA:3.40.50.620 24 620 8.8E-267 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Pfam PF06827 Zinc finger found in FPG and IleRS 885 914 1.1E-7 T 01-11-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 831 0.0 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Gene3D G3DSA:3.90.740.10 193 397 8.8E-267 T 01-11-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Pfam PF08264 Anticodon-binding domain of tRNA 676 829 2.9E-31 T 01-11-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 6.8E-33 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 6.8E-33 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 6.8E-33 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 6.8E-33 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 6.8E-33 T 01-11-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 21.182 T 01-11-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 1.3E-223 T 01-11-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 Gene3D G3DSA:1.10.730.20 631 918 1.6E-102 T 01-11-2018 MLA2C4_20360 649d257c8b32c30d4d4f104d4e2659e5 921 SUPERFAMILY SSF47323 643 917 5.05E-81 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_28215 d1d05253b344fe4938c40bfbff578fc3 295 Gene3D G3DSA:3.40.50.720 2 295 4.9E-31 T 01-11-2018 MLA2C4_28215 d1d05253b344fe4938c40bfbff578fc3 295 SUPERFAMILY SSF51735 7 292 1.07E-33 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_28215 d1d05253b344fe4938c40bfbff578fc3 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 203 2.4E-9 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 4.3E-148 T 01-11-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 7.2E-65 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 Gene3D G3DSA:3.40.50.720 3 273 2.7E-146 T 01-11-2018 MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 Gene3D G3DSA:3.90.25.10 193 328 2.7E-146 T 01-11-2018 MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 SUPERFAMILY SSF51735 1 335 2.25E-96 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 1.7E-5 T 01-11-2018 MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 1.7E-5 T 01-11-2018 MLA2C4_28260 1e584d7a967054597d6cf2e523119454 338 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 1.7E-5 T 01-11-2018 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 Gene3D G3DSA:3.40.50.720 2 331 1.1E-129 T 01-11-2018 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 SUPERFAMILY SSF55347 149 313 2.55E-54 T 01-11-2018 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 SUPERFAMILY SSF51735 2 177 1.13E-49 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 SMART SM00859 2 141 4.2E-53 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 141 2.5E-35 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 344 9.1E-140 T 01-11-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 01-11-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 316 1.4E-27 T 01-11-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 44.92 T 01-11-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21620 fd0fde3b667ea7291d80a42b655237c8 345 Gene3D G3DSA:3.30.360.10 147 313 1.1E-129 T 01-11-2018 MLA2C4_11185 2ba2511ac7fc3893bb25bbe66503f14d 485 SUPERFAMILY SSF56601 8 344 7.66E-85 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_11185 2ba2511ac7fc3893bb25bbe66503f14d 485 Pfam PF11954 Domain of unknown function (DUF3471) 385 481 5.6E-20 T 01-11-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal MLA2C4_11185 2ba2511ac7fc3893bb25bbe66503f14d 485 Pfam PF00144 Beta-lactamase 13 337 4.1E-61 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_11185 2ba2511ac7fc3893bb25bbe66503f14d 485 Gene3D G3DSA:2.40.128.600 381 466 1.1E-6 T 01-11-2018 MLA2C4_11185 2ba2511ac7fc3893bb25bbe66503f14d 485 Gene3D G3DSA:3.40.710.10 2 346 2.8E-92 T 01-11-2018 MLA2C4_15540 bfa7058f04486f31f1900dd622213d7d 1038 SUPERFAMILY SSF82866 140 337 6.15E-31 T 01-11-2018 MLA2C4_15540 bfa7058f04486f31f1900dd622213d7d 1038 Gene3D G3DSA:1.20.1640.10 156 339 2.5E-7 T 01-11-2018 MLA2C4_15540 bfa7058f04486f31f1900dd622213d7d 1038 SUPERFAMILY SSF82866 861 1026 3.4E-23 T 01-11-2018 MLA2C4_15540 bfa7058f04486f31f1900dd622213d7d 1038 Pfam PF03176 MMPL family 732 1028 1.7E-39 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MLA2C4_15540 bfa7058f04486f31f1900dd622213d7d 1038 Pfam PF03176 MMPL family 42 366 1.5E-58 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MLA2C4_15540 bfa7058f04486f31f1900dd622213d7d 1038 SUPERFAMILY SSF58104 485 615 5.49E-5 T 01-11-2018 MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 30 99 1.4E-16 T 01-11-2018 IPR001543 Surface presentation of antigen (SpoA) MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 76 91 1.4E-10 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 63 76 1.4E-10 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 30 46 1.4E-10 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 47 63 1.4E-10 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 Gene3D G3DSA:2.30.330.10 17 110 1.3E-18 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 27 102 8.7E-25 T 01-11-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 MLA2C4_08695 f86b6c1b5325790eba8d5a6c8ba7dd98 119 SUPERFAMILY SSF101801 27 103 5.49E-17 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 Gene3D G3DSA:2.60.40.1430 404 512 3.2E-47 T 01-11-2018 IPR038700 Thiol-activated cytolysin, C-terminal domain superfamily MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 ProSitePatterns PS00481 Thiol-activated cytolysins signature. 470 481 - T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 Gene3D G3DSA:3.90.840.10 51 386 3.9E-139 T 01-11-2018 IPR036363 Thiol-activated cytolysin, alpha-beta domain superfamily GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 SUPERFAMILY SSF56978 46 511 7.06E-204 T 01-11-2018 IPR036359 Thiol-activated cytolysin superfamily GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 Pfam PF01289 Thiol-activated cytolysin 51 402 6.7E-145 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 Pfam PF17440 Thiol-activated cytolysin beta sandwich domain 407 506 1.2E-39 T 01-11-2018 IPR035390 Thiol-activated cytolysin C-terminal MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 Gene3D G3DSA:3.40.30.40 192 362 3.9E-139 T 01-11-2018 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 Gene3D G3DSA:3.30.1040.20 67 398 3.9E-139 T 01-11-2018 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 116 132 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 190 205 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 271 294 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 324 341 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 428 444 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 486 506 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 372 399 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 411 428 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 132 150 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 58 75 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_26480 a91e20be6367af4ab15f20abba627268 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 88 110 2.3E-103 T 01-11-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 MLA2C4_22085 3b2fb307a014a590f9dee456a31aa1d1 290 Gene3D G3DSA:3.40.50.300 1 226 3.4E-51 T 01-11-2018 MLA2C4_22085 3b2fb307a014a590f9dee456a31aa1d1 290 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_22085 3b2fb307a014a590f9dee456a31aa1d1 290 SUPERFAMILY SSF52540 2 218 1.46E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22085 3b2fb307a014a590f9dee456a31aa1d1 290 Pfam PF00005 ABC transporter 16 155 1.1E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_22085 3b2fb307a014a590f9dee456a31aa1d1 290 SMART SM00382 25 204 2.7E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_11585 0f8c17f9afe0ee5b6d06702b70581900 64 Pfam PF12844 Helix-turn-helix domain 5 63 3.3E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_11585 0f8c17f9afe0ee5b6d06702b70581900 64 SUPERFAMILY SSF47413 4 63 4.22E-10 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_11585 0f8c17f9afe0ee5b6d06702b70581900 64 Gene3D G3DSA:1.10.260.40 4 64 1.2E-11 T 01-11-2018 MLA2C4_11585 0f8c17f9afe0ee5b6d06702b70581900 64 SMART SM00530 6 62 1.1E-8 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 Pfam PF00625 Guanylate kinase 8 184 1.3E-53 T 01-11-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 188 37.169 T 01-11-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 3.1E-74 T 01-11-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 01-11-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 SMART SM00072 5 188 1.1E-79 T 01-11-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 Gene3D G3DSA:3.40.50.300 10 184 1.4E-68 T 01-11-2018 MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 SUPERFAMILY SSF52540 3 192 8.04E-70 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20230 159570803c20cef18f1cbbcb9c0d1b93 205 Gene3D G3DSA:3.30.63.10 38 97 1.4E-68 T 01-11-2018 MLA2C4_15175 de8a016f6b638d5419779191b4c6c178 422 Pfam PF13520 Amino acid permease 10 390 1.1E-37 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_15175 de8a016f6b638d5419779191b4c6c178 422 PIRSF PIRSF006060 1 416 1.4E-58 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_15175 de8a016f6b638d5419779191b4c6c178 422 Gene3D G3DSA:1.20.1740.10 4 422 1.5E-62 T 01-11-2018 MLA2C4_20710 6008bc9fbdd0165d8e7e6eedc3bde92e 42 Pfam PF13790 SR1 protein 1 37 2.8E-16 T 01-11-2018 IPR025236 SR1 protein MLA2C4_19880 0e3b6f919ad2d5986fb0d1a8ef2a06a3 199 Pfam PF02441 Flavoprotein 6 160 1.5E-18 T 01-11-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MLA2C4_19880 0e3b6f919ad2d5986fb0d1a8ef2a06a3 199 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 7.1E-106 T 01-11-2018 IPR014214 Dipicolinic acid synthetase, subunit B MLA2C4_19880 0e3b6f919ad2d5986fb0d1a8ef2a06a3 199 Gene3D G3DSA:3.40.50.1950 1 199 1.1E-60 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MLA2C4_19880 0e3b6f919ad2d5986fb0d1a8ef2a06a3 199 PIRSF PIRSF001390 1 195 7.2E-81 T 01-11-2018 IPR014214 Dipicolinic acid synthetase, subunit B MLA2C4_19880 0e3b6f919ad2d5986fb0d1a8ef2a06a3 199 SUPERFAMILY SSF52507 3 180 1.96E-31 T 01-11-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 Pfam PF01565 FAD binding domain 41 180 1.0E-42 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 456 3.4E-74 T 01-11-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 Gene3D G3DSA:3.30.465.40 3 237 4.5E-78 T 01-11-2018 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 1.8E-180 T 01-11-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 SUPERFAMILY SSF55103 220 460 1.8E-70 T 01-11-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 Gene3D G3DSA:3.30.70.2740 336 417 2.0E-14 T 01-11-2018 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 SUPERFAMILY SSF56176 5 217 4.49E-76 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_06895 b299b7b41130f56f986723ee9f9c4885 470 Gene3D G3DSA:1.10.45.10 418 457 2.5E-11 T 01-11-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MLA2C4_03900 08325e731c4d7013333b8e65d0c3735b 139 Pfam PF00571 CBS domain 4 54 5.4E-11 T 01-11-2018 IPR000644 CBS domain MLA2C4_03900 08325e731c4d7013333b8e65d0c3735b 139 Pfam PF00571 CBS domain 69 118 1.1E-12 T 01-11-2018 IPR000644 CBS domain MLA2C4_03900 08325e731c4d7013333b8e65d0c3735b 139 Gene3D G3DSA:3.10.580.10 1 138 2.1E-36 T 01-11-2018 MLA2C4_03900 08325e731c4d7013333b8e65d0c3735b 139 SMART SM00116 11 58 1.6E-4 T 01-11-2018 IPR000644 CBS domain MLA2C4_03900 08325e731c4d7013333b8e65d0c3735b 139 SMART SM00116 75 122 2.0E-11 T 01-11-2018 IPR000644 CBS domain MLA2C4_03900 08325e731c4d7013333b8e65d0c3735b 139 SUPERFAMILY SSF54631 1 117 1.89E-33 T 01-11-2018 MLA2C4_17540 f6226b47145dae90eac998b7ad95e4de 489 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 328 406 2.7E-19 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_17540 f6226b47145dae90eac998b7ad95e4de 489 Pfam PF07282 Putative transposase DNA-binding domain 380 459 2.8E-6 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_17540 f6226b47145dae90eac998b7ad95e4de 489 Pfam PF01385 Probable transposase 247 359 6.2E-18 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Gene3D G3DSA:3.40.50.10730 140 352 3.2E-97 T 01-11-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Pfam PF17391 Urocanase N-terminal domain 8 134 2.0E-63 T 01-11-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Pfam PF17392 Urocanase C-terminal domain 348 542 9.9E-96 T 01-11-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 PIRSF PIRSF001423 1 552 4.9E-303 T 01-11-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Gene3D G3DSA:3.40.1770.10 353 552 6.9E-94 T 01-11-2018 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Gene3D G3DSA:3.40.1770.10 2 139 1.6E-64 T 01-11-2018 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 SUPERFAMILY SSF111326 5 551 4.32E-266 T 01-11-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 550 0.0 T 01-11-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 01-11-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Hamap MF_00577 Urocanate hydratase [hutU]. 5 552 51.597 T 01-11-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_18970 49aece1e53d51b2fa2637d18e24da62c 552 Pfam PF01175 Urocanase Rossmann-like domain 137 345 3.3E-92 T 01-11-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MLA2C4_21545 dbd32529801453c63121b19f1dd795db 246 Gene3D G3DSA:3.40.50.1820 3 232 1.0E-32 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_21545 dbd32529801453c63121b19f1dd795db 246 SUPERFAMILY SSF53474 6 232 5.72E-29 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_21545 dbd32529801453c63121b19f1dd795db 246 Pfam PF12146 Serine aminopeptidase, S33 43 215 3.7E-10 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_06670 04e16153cc0f1539a1f3064d36a903bb 747 SUPERFAMILY SSF52540 406 624 3.49E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06670 04e16153cc0f1539a1f3064d36a903bb 747 Pfam PF07728 AAA domain (dynein-related subfamily) 431 599 7.8E-9 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 SUPERFAMILY SSF89260 503 612 3.92E-32 T 01-11-2018 MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 SUPERFAMILY SSF52743 180 460 1.03E-35 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 Gene3D G3DSA:2.60.120.380 501 613 4.2E-25 T 01-11-2018 MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 PRINTS PR00723 Subtilisin serine protease family (S8) signature 421 437 6.5E-9 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 PRINTS PR00723 Subtilisin serine protease family (S8) signature 234 247 6.5E-9 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 6.5E-9 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 Gene3D G3DSA:3.40.50.200 164 500 1.0E-34 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 534 599 6.1E-6 T 01-11-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 422 432 - T 01-11-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MLA2C4_19655 e8b4c4b50942e5776fc6e2dc2720bdcf 613 Pfam PF00082 Subtilase family 214 467 5.5E-17 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MLA2C4_10285 6a60839ffd9e6f632c38949b2cde3a34 194 Gene3D G3DSA:3.40.630.30 10 185 8.8E-41 T 01-11-2018 MLA2C4_10285 6a60839ffd9e6f632c38949b2cde3a34 194 SUPERFAMILY SSF55729 10 185 2.76E-40 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10285 6a60839ffd9e6f632c38949b2cde3a34 194 Pfam PF13302 Acetyltransferase (GNAT) domain 16 159 7.6E-25 T 01-11-2018 IPR000182 GNAT domain MLA2C4_19380 ab1b8ca862a5954210087677e788881c 321 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 11 83 3.5E-7 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_19380 ab1b8ca862a5954210087677e788881c 321 Pfam PF00589 Phage integrase family 150 312 4.8E-9 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_19380 ab1b8ca862a5954210087677e788881c 321 Gene3D G3DSA:1.10.443.10 110 316 4.4E-16 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_19380 ab1b8ca862a5954210087677e788881c 321 SUPERFAMILY SSF56349 117 316 1.5E-19 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_19380 ab1b8ca862a5954210087677e788881c 321 Gene3D G3DSA:1.10.150.130 6 101 4.0E-11 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_19380 ab1b8ca862a5954210087677e788881c 321 SUPERFAMILY SSF47823 15 110 1.22E-6 T 01-11-2018 MLA2C4_26320 4c41643a03c2196cc5bca4cda3ac9efb 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 3.5E-21 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_26320 4c41643a03c2196cc5bca4cda3ac9efb 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 2.2E-57 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_26520 2e4acd1b94493daacd6e393610d42887 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 2 360 7.3E-65 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_26520 2e4acd1b94493daacd6e393610d42887 362 Pfam PF03845 Spore germination protein 2 324 2.5E-58 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_25140 ab66bb58e43842bb089cb2d7dc389718 649 PIRSF PIRSF018968 1 649 1.9E-127 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_25140 ab66bb58e43842bb089cb2d7dc389718 649 Pfam PF02687 FtsX-like permease family 85 170 2.5E-9 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 SUPERFAMILY SSF55129 3 59 4.06E-21 T 01-11-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 55 7.5E-21 T 01-11-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 6.4E-27 T 01-11-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 01-11-2018 IPR018038 Ribosomal protein L30, conserved site MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 Gene3D G3DSA:3.30.1390.20 1 59 2.6E-27 T 01-11-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.989 T 01-11-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00765 d8c77e279dee38be63ece5fbb1c5080f 60 PIRSF PIRSF002211 1 60 2.7E-29 T 01-11-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_04875 b5c787d7868b344859bd2c395141d40a 350 PIRSF PIRSF029792 17 350 1.9E-135 T 01-11-2018 IPR008794 Proline racemase family MLA2C4_04875 b5c787d7868b344859bd2c395141d40a 350 Gene3D G3DSA:3.10.310.10 162 326 8.4E-128 T 01-11-2018 MLA2C4_04875 b5c787d7868b344859bd2c395141d40a 350 SUPERFAMILY SSF54506 17 347 8.41E-108 T 01-11-2018 MLA2C4_04875 b5c787d7868b344859bd2c395141d40a 350 Gene3D G3DSA:3.10.310.10 24 349 8.4E-128 T 01-11-2018 MLA2C4_04875 b5c787d7868b344859bd2c395141d40a 350 Pfam PF05544 Proline racemase 26 347 2.4E-104 T 01-11-2018 IPR008794 Proline racemase family MLA2C4_16805 97f2a5917a20bb47363fda38f3980fe1 618 Gene3D G3DSA:3.40.50.720 1 313 2.1E-41 T 01-11-2018 MLA2C4_16805 97f2a5917a20bb47363fda38f3980fe1 618 SUPERFAMILY SSF51735 1 294 4.87E-32 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_16805 97f2a5917a20bb47363fda38f3980fe1 618 Pfam PF12697 Alpha/beta hydrolase family 382 607 1.5E-10 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16805 97f2a5917a20bb47363fda38f3980fe1 618 Gene3D G3DSA:3.40.50.1820 350 615 6.6E-22 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16805 97f2a5917a20bb47363fda38f3980fe1 618 SUPERFAMILY SSF53474 373 611 7.71E-21 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16805 97f2a5917a20bb47363fda38f3980fe1 618 Pfam PF07993 Male sterility protein 6 239 5.1E-41 T 01-11-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MLA2C4_14330 03f0a2b2aa6dace7b121b82f70f7861a 283 SUPERFAMILY SSF52151 2 274 7.32E-47 T 01-11-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MLA2C4_14330 03f0a2b2aa6dace7b121b82f70f7861a 283 Pfam PF01734 Patatin-like phospholipase 6 170 3.2E-20 T 01-11-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MLA2C4_14330 03f0a2b2aa6dace7b121b82f70f7861a 283 Gene3D G3DSA:3.40.1090.10 1 91 7.4E-15 T 01-11-2018 MLA2C4_18920 23a3ae8dccada6f12a2156e1fdb01eba 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 118 2.2E-7 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18920 23a3ae8dccada6f12a2156e1fdb01eba 123 SUPERFAMILY SSF54593 5 122 2.01E-21 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18920 23a3ae8dccada6f12a2156e1fdb01eba 123 Gene3D G3DSA:3.10.180.10 9 123 1.5E-33 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_10195 bc64aa259e4067738702cefe4b90597b 311 Pfam PF00248 Aldo/keto reductase family 15 309 4.8E-75 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_10195 bc64aa259e4067738702cefe4b90597b 311 SUPERFAMILY SSF51430 1 310 2.75E-94 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_10195 bc64aa259e4067738702cefe4b90597b 311 PRINTS PR00069 Aldo-keto reductase signature 44 68 1.1E-9 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_10195 bc64aa259e4067738702cefe4b90597b 311 PRINTS PR00069 Aldo-keto reductase signature 109 127 1.1E-9 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_10195 bc64aa259e4067738702cefe4b90597b 311 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.1E-9 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_10195 bc64aa259e4067738702cefe4b90597b 311 Gene3D G3DSA:3.20.20.100 1 311 2.4E-107 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 511 3.0E-245 T 01-11-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 PIRSF PIRSF000414 1 511 7.8E-217 T 01-11-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 Gene3D G3DSA:3.40.140.20 378 511 1.3E-57 T 01-11-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 SUPERFAMILY SSF52335 2 194 1.33E-69 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 Pfam PF02142 MGS-like domain 14 129 3.8E-26 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 511 45.994 T 01-11-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 SMART SM00851 14 129 8.4E-55 T 01-11-2018 IPR011607 Methylglyoxal synthase-like domain MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 Gene3D G3DSA:3.40.50.1380 1 198 1.5E-87 T 01-11-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 444 2.5E-124 T 01-11-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 SMART SM00798 134 446 6.4E-202 T 01-11-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 Gene3D G3DSA:3.40.140.20 203 360 1.3E-61 T 01-11-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MLA2C4_01795 4497add3d4a6941d77a17cdfe5b70cb6 511 SUPERFAMILY SSF53927 206 511 1.5E-130 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_13550 6bcc0f0db3642b89b0ae8c429e9e8109 211 Gene3D G3DSA:3.40.50.720 2 210 7.7E-40 T 01-11-2018 MLA2C4_13550 6bcc0f0db3642b89b0ae8c429e9e8109 211 Pfam PF13460 NAD(P)H-binding 11 199 4.0E-35 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_13550 6bcc0f0db3642b89b0ae8c429e9e8109 211 SUPERFAMILY SSF51735 5 210 1.18E-31 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_20590 c92d344d815567a364a5a78e7d73aecc 207 Gene3D G3DSA:1.20.120.80 21 206 9.3E-53 T 01-11-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20590 c92d344d815567a364a5a78e7d73aecc 207 SUPERFAMILY SSF81452 21 204 3.01E-56 T 01-11-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20590 c92d344d815567a364a5a78e7d73aecc 207 Pfam PF00510 Cytochrome c oxidase subunit III 28 204 8.0E-20 T 01-11-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_13305 65a5adacd99e8ca706cfaf9c0272f0be 219 Gene3D G3DSA:2.160.10.10 3 218 2.4E-64 T 01-11-2018 MLA2C4_13305 65a5adacd99e8ca706cfaf9c0272f0be 219 SUPERFAMILY SSF51161 33 212 8.04E-43 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_13305 65a5adacd99e8ca706cfaf9c0272f0be 219 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 1.1E-10 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_13305 65a5adacd99e8ca706cfaf9c0272f0be 219 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 Pfam PF00571 CBS domain 77 128 4.0E-9 T 01-11-2018 IPR000644 CBS domain MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 Pfam PF00571 CBS domain 3 56 5.5E-16 T 01-11-2018 IPR000644 CBS domain MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 Pfam PF01842 ACT domain 139 199 3.9E-10 T 01-11-2018 IPR002912 ACT domain MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 SUPERFAMILY SSF54631 1 127 1.11E-30 T 01-11-2018 MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 140 205 0.004 T 01-11-2018 MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 Gene3D G3DSA:3.30.70.260 133 204 3.4E-7 T 01-11-2018 MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 SUPERFAMILY SSF55021 137 206 4.84E-11 T 01-11-2018 MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 SMART SM00116 81 128 3.2E-9 T 01-11-2018 IPR000644 CBS domain MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 SMART SM00116 10 58 1.6E-12 T 01-11-2018 IPR000644 CBS domain MLA2C4_24235 1867fdbbe6c52fdb51da4fefee8b0f0d 214 Gene3D G3DSA:3.10.580.10 1 132 1.6E-33 T 01-11-2018 MLA2C4_27050 50d269208b784a20e29079ec7efa56e8 121 Pfam PF06803 Protein of unknown function (DUF1232) 45 80 2.8E-13 T 01-11-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 MLA2C4_27050 50d269208b784a20e29079ec7efa56e8 121 PIRSF PIRSF031804 1 110 7.6E-43 T 01-11-2018 IPR016983 Uncharacterised conserved protein UCP031804 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 5.2E-39 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 1.2E-25 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 2.3E-56 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 Gene3D G3DSA:1.20.140.10 235 380 2.7E-58 T 01-11-2018 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 SUPERFAMILY SSF56645 2 243 1.01E-87 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 PIRSF PIRSF016578 2 378 3.9E-23 T 01-11-2018 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 Gene3D G3DSA:2.40.110.10 122 234 4.3E-41 T 01-11-2018 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 SUPERFAMILY SSF47203 229 378 4.49E-61 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MLA2C4_13460 c0016e20ac23b5e48c8cc979b482ea3f 381 Gene3D G3DSA:1.10.540.10 1 120 1.0E-45 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MLA2C4_03395 a54e30584c2d083b03f1aa2e82af3390 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 212 1.1E-18 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03395 a54e30584c2d083b03f1aa2e82af3390 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 5.2E-28 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MLA2C4_03395 a54e30584c2d083b03f1aa2e82af3390 214 Gene3D G3DSA:1.10.3720.10 10 214 8.9E-51 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03395 a54e30584c2d083b03f1aa2e82af3390 214 SUPERFAMILY SSF161098 15 209 1.09E-43 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 Pfam PF13538 UvrD-like helicase C-terminal domain 1037 1082 5.3E-14 T 01-11-2018 IPR027785 UvrD-like helicase C-terminal domain MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 SUPERFAMILY SSF52540 626 1090 1.07E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 Gene3D G3DSA:3.40.50.300 797 1088 8.8E-62 T 01-11-2018 MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 Gene3D G3DSA:3.40.50.300 616 796 8.8E-62 T 01-11-2018 MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 Pfam PF13604 AAA domain 624 799 1.2E-27 T 01-11-2018 MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 SMART SM00382 632 800 0.0015 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_06745 1a1cada3d6539346f8fb7643ee1341a0 1251 Gene3D G3DSA:2.30.30.940 925 1037 8.8E-62 T 01-11-2018 MLA2C4_04175 db980c1ee21e12148bccb57669d4473c 115 SUPERFAMILY SSF47413 3 59 2.33E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_04175 db980c1ee21e12148bccb57669d4473c 115 Pfam PF12844 Helix-turn-helix domain 6 59 2.5E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_04175 db980c1ee21e12148bccb57669d4473c 115 Gene3D G3DSA:1.10.260.40 2 105 3.1E-12 T 01-11-2018 MLA2C4_04175 db980c1ee21e12148bccb57669d4473c 115 SMART SM00530 8 64 6.4E-8 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_21525 de5c271037d1bac6d71c9acb9f211c66 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 152 31.566 T 01-11-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21525 de5c271037d1bac6d71c9acb9f211c66 153 SUPERFAMILY SSF52121 2 152 5.1E-64 T 01-11-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21525 de5c271037d1bac6d71c9acb9f211c66 153 Gene3D G3DSA:3.40.50.960 1 153 1.2E-67 T 01-11-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21525 de5c271037d1bac6d71c9acb9f211c66 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 11 149 1.7E-60 T 01-11-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21525 de5c271037d1bac6d71c9acb9f211c66 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 147 5.1E-60 T 01-11-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_01015 1290b9044bd452669918a4608cda567d 222 SUPERFAMILY SSF161098 13 206 3.01E-43 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01015 1290b9044bd452669918a4608cda567d 222 Gene3D G3DSA:1.10.3720.10 9 222 1.1E-48 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01015 1290b9044bd452669918a4608cda567d 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 205 2.7E-22 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_25725 9c92d9f6e4dec3ba1b2750af19ad1c8e 219 Pfam PF00005 ABC transporter 18 156 1.4E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_25725 9c92d9f6e4dec3ba1b2750af19ad1c8e 219 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_25725 9c92d9f6e4dec3ba1b2750af19ad1c8e 219 SMART SM00382 22 205 1.3E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25725 9c92d9f6e4dec3ba1b2750af19ad1c8e 219 Gene3D G3DSA:3.40.50.300 5 219 2.7E-56 T 01-11-2018 MLA2C4_25725 9c92d9f6e4dec3ba1b2750af19ad1c8e 219 SUPERFAMILY SSF52540 1 211 8.71E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26280 876f4f56f974bf28913873b8dfb7d0ae 165 PIRSF PIRSF005028 1 162 8.7E-56 T 01-11-2018 IPR026278 Potassium/proton antiporter subunit KhtT MLA2C4_26280 876f4f56f974bf28913873b8dfb7d0ae 165 Pfam PF02080 TrkA-C domain 89 158 1.9E-15 T 01-11-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MLA2C4_26280 876f4f56f974bf28913873b8dfb7d0ae 165 Gene3D G3DSA:3.30.70.1450 83 161 6.1E-19 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_26280 876f4f56f974bf28913873b8dfb7d0ae 165 SUPERFAMILY SSF116726 77 157 4.71E-17 T 01-11-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.561 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 Pfam PF01016 Ribosomal L27 protein 10 89 5.4E-34 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 5.0E-17 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 01-11-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 1.8E-37 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 1.8E-37 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 1.8E-37 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.7E-39 T 01-11-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 SUPERFAMILY SSF110324 10 91 1.6E-31 T 01-11-2018 MLA2C4_23160 b64a514b5f6a2a0cda12989078f57a28 96 Gene3D G3DSA:2.40.50.100 28 93 1.2E-25 T 01-11-2018 MLA2C4_16570 381804dbdbd912de09aaad6a1c33ca1e 316 Gene3D G3DSA:1.20.58.340 120 241 6.8E-7 T 01-11-2018 MLA2C4_16570 381804dbdbd912de09aaad6a1c33ca1e 316 SUPERFAMILY SSF143865 73 223 8.63E-9 T 01-11-2018 MLA2C4_16570 381804dbdbd912de09aaad6a1c33ca1e 316 Pfam PF01544 CorA-like Mg2+ transporter protein 11 295 8.0E-37 T 01-11-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MLA2C4_16570 381804dbdbd912de09aaad6a1c33ca1e 316 SUPERFAMILY SSF144083 236 297 2.22E-17 T 01-11-2018 MLA2C4_16570 381804dbdbd912de09aaad6a1c33ca1e 316 Gene3D G3DSA:1.20.58.340 243 300 2.6E-14 T 01-11-2018 MLA2C4_00985 42734d64cafd2e11a7157955cdae0d96 188 Pfam PF14066 Protein of unknown function (DUF4256) 16 188 6.2E-92 T 01-11-2018 IPR025352 Protein of unknown function DUF4256 MLA2C4_15775 908095c9954ae0823bb10b277752c61d 395 Gene3D G3DSA:3.90.1860.10 5 394 1.3E-72 T 01-11-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MLA2C4_15775 908095c9954ae0823bb10b277752c61d 395 Pfam PF01139 tRNA-splicing ligase RtcB 38 393 1.3E-66 T 01-11-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MLA2C4_15775 908095c9954ae0823bb10b277752c61d 395 SUPERFAMILY SSF103365 5 394 6.8E-107 T 01-11-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 SUPERFAMILY SSF53720 27 425 2.75E-83 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PIRSF PIRSF000099 2 428 5.4E-184 T 01-11-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 425 43.375 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 Gene3D G3DSA:3.40.50.1980 30 229 6.8E-128 T 01-11-2018 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 318 343 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 359 377 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 1.4E-90 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 424 2.3E-169 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 Gene3D G3DSA:3.40.50.1980 231 347 6.8E-128 T 01-11-2018 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 01-11-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_07435 83a852932d07e29f417c441a63febc2b 429 Pfam PF00815 Histidinol dehydrogenase 26 425 1.1E-175 T 01-11-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MLA2C4_15405 f59502991c05acf6b55252b4b91c9e7a 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 6.5E-22 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_15405 f59502991c05acf6b55252b4b91c9e7a 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 1.2E-26 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_07715 7a12acca1493d548e7fe4599846ebb5e 235 Gene3D G3DSA:3.40.50.1580 1 235 5.6E-80 T 01-11-2018 MLA2C4_07715 7a12acca1493d548e7fe4599846ebb5e 235 SUPERFAMILY SSF53167 2 233 1.83E-94 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MLA2C4_07715 7a12acca1493d548e7fe4599846ebb5e 235 Pfam PF01048 Phosphorylase superfamily 16 222 1.8E-43 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MLA2C4_07715 7a12acca1493d548e7fe4599846ebb5e 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 4.8E-109 T 01-11-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MLA2C4_07715 7a12acca1493d548e7fe4599846ebb5e 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 49.249 T 01-11-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MLA2C4_07715 7a12acca1493d548e7fe4599846ebb5e 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 01-11-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MLA2C4_27575 d9161e504122b09379507acab10c2dbe 287 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 37 162 4.2E-47 T 01-11-2018 IPR014202 Sporulation stage II, protein R MLA2C4_27575 d9161e504122b09379507acab10c2dbe 287 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 3 168 6.4E-60 T 01-11-2018 IPR014202 Sporulation stage II, protein R MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.581 T 01-11-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 SUPERFAMILY SSF75620 8 351 3.4E-133 T 01-11-2018 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 353 5.5E-170 T 01-11-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 Pfam PF03462 PCRF domain 9 202 3.5E-73 T 01-11-2018 IPR005139 Peptide chain release factor GO:0006415 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 Gene3D G3DSA:3.30.160.20 209 295 8.4E-96 T 01-11-2018 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 01-11-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 Pfam PF00472 RF-1 domain 210 319 4.2E-40 T 01-11-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 Gene3D G3DSA:1.20.58.410 2 101 1.4E-6 T 01-11-2018 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 SMART SM00937 62 177 1.4E-63 T 01-11-2018 IPR005139 Peptide chain release factor GO:0006415 MLA2C4_27585 c892da6625f4ccecae116e213bf6408d 355 Gene3D G3DSA:3.30.70.1660 110 340 8.4E-96 T 01-11-2018 MLA2C4_02790 6202ae9e9c59b7719efb215c0c2b775f 118 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 4 115 6.0E-62 T 01-11-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 MLA2C4_02790 6202ae9e9c59b7719efb215c0c2b775f 118 Pfam PF11023 Zinc-ribbon containing domain 4 114 2.1E-59 T 01-11-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 MLA2C4_02790 6202ae9e9c59b7719efb215c0c2b775f 118 Hamap MF_01502 UPF0295 protein . 2 116 37.732 T 01-11-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 MLA2C4_04300 b575ad1a942bb4145cba563707af29b5 159 Gene3D G3DSA:3.40.1260.10 1 159 3.0E-65 T 01-11-2018 IPR027396 DsrEFH-like MLA2C4_04300 b575ad1a942bb4145cba563707af29b5 159 SUPERFAMILY SSF75169 5 157 3.01E-23 T 01-11-2018 IPR027396 DsrEFH-like MLA2C4_04300 b575ad1a942bb4145cba563707af29b5 159 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 158 3.0E-67 T 01-11-2018 IPR032836 DsrE2-like family MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 Pfam PF00717 Peptidase S24-like 35 102 2.7E-19 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 01-11-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 Gene3D G3DSA:2.10.109.10 58 182 3.2E-46 T 01-11-2018 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 2.4E-19 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 2.4E-19 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 2.4E-19 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 01-11-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 1.6E-56 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 01-11-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MLA2C4_20065 8e9d319cf90943c1787c8da323abf9db 183 SUPERFAMILY SSF51306 26 181 2.41E-51 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_19100 772a74c3d5624cedf2af8d344a7085ba 225 Pfam PF04172 LrgB-like family 10 222 8.4E-70 T 01-11-2018 IPR007300 CidB/LrgB family MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 783 18.12 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Pfam PF07516 SecA Wing and Scaffold domain 573 778 8.4E-43 T 01-11-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 ProSitePatterns PS01312 SecA family signature. 481 496 - T 01-11-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Gene3D G3DSA:1.10.1200.230 622 706 0.0 T 01-11-2018 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 SUPERFAMILY SSF52540 3 396 5.66E-76 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 TIGRFAM TIGR04397 SecA2_Bac_anthr: accessory Sec system translocase SecA2 5 780 0.0 T 01-11-2018 IPR030908 Protein translocase subunit SecA 2, Bacillus anthracis-type MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Gene3D G3DSA:3.40.50.300 15 397 0.0 T 01-11-2018 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Pfam PF07517 SecA DEAD-like domain 6 383 7.6E-122 T 01-11-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 SUPERFAMILY SSF81767 230 349 6.93E-41 T 01-11-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 497 1.0E-212 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Pfam PF01043 SecA preprotein cross-linking domain 232 339 8.4E-32 T 01-11-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Gene3D G3DSA:1.10.3060.10 572 778 0.0 T 01-11-2018 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 SUPERFAMILY SSF52540 397 566 2.76E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 SMART SM00958 227 339 2.0E-53 T 01-11-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 SMART SM00957 5 383 1.0E-249 T 01-11-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 394 407 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 169 189 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 116 126 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 357 374 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 62 86 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 100 114 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 PRINTS PR00906 SecA protein signature 320 342 5.0E-64 T 01-11-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Gene3D G3DSA:3.40.50.300 398 571 0.0 T 01-11-2018 MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 SUPERFAMILY SSF81886 574 781 4.97E-52 T 01-11-2018 IPR036266 SecA, Wing/Scaffold superfamily MLA2C4_04780 507827382e74c100979afd0de5a44c43 788 Gene3D G3DSA:3.90.1440.10 228 349 0.0 T 01-11-2018 MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 Gene3D G3DSA:3.10.350.10 158 204 5.8E-15 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 SUPERFAMILY SSF54106 160 203 1.31E-10 T 01-11-2018 MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 Pfam PF01476 LysM domain 162 203 6.1E-13 T 01-11-2018 IPR018392 LysM domain MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 SMART SM00257 161 204 8.9E-11 T 01-11-2018 IPR018392 LysM domain MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 SUPERFAMILY SSF51261 24 149 4.34E-41 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 Pfam PF01551 Peptidase family M23 46 139 2.1E-27 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_07795 ebb99d79e1cec5cadcb1582193a436eb 204 Gene3D G3DSA:2.70.70.10 15 150 6.4E-38 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_08830 982ed44171b43ef9b6cf481f25b9fdb0 174 Pfam PF14346 Domain of unknown function (DUF4398) 12 119 5.1E-15 T 01-11-2018 IPR025511 Domain of unknown function DUF4398 MLA2C4_08830 982ed44171b43ef9b6cf481f25b9fdb0 174 SUPERFAMILY SSF48452 20 96 6.7E-5 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 24.895 T 01-11-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 SUPERFAMILY SSF50346 100 170 1.82E-21 T 01-11-2018 IPR011033 PRC-barrel-like superfamily MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 Gene3D G3DSA:2.40.30.60 5 93 4.9E-22 T 01-11-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 Pfam PF01782 RimM N-terminal domain 7 91 1.9E-23 T 01-11-2018 IPR002676 RimM, N-terminal GO:0006364 MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 170 5.3E-54 T 01-11-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 SUPERFAMILY SSF50447 3 92 3.8E-22 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 Gene3D G3DSA:2.30.30.240 95 171 1.0E-21 T 01-11-2018 MLA2C4_20080 fadc9cadc7b0811f0f43978225b62d4d 171 Pfam PF05239 PRC-barrel domain 97 170 1.1E-14 T 01-11-2018 IPR027275 PRC-barrel domain MLA2C4_20765 a1a826a08741bcaaaa1f8849db5130ef 48 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 22 45 2.4E-13 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_20765 a1a826a08741bcaaaa1f8849db5130ef 48 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 26 47 2.3E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 SUPERFAMILY SSF55174 321 417 1.96E-24 T 01-11-2018 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 Gene3D G3DSA:1.10.240.10 223 325 1.2E-39 T 01-11-2018 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 SUPERFAMILY SSF52374 2 323 1.5E-107 T 01-11-2018 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 Gene3D G3DSA:3.40.50.620 1 222 5.4E-89 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 3.2E-87 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 46.768 T 01-11-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 Gene3D G3DSA:3.10.290.10 326 418 3.6E-35 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 7.6E-32 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 7.6E-32 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 7.6E-32 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 7.6E-32 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 Pfam PF01479 S4 domain 356 399 3.8E-8 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 417 2.8E-139 T 01-11-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MLA2C4_24200 de2c79d9c46565ce94c870cf608adb08 418 SMART SM00363 353 414 2.4E-8 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_14935 b7b00914ce9b420acaeaf7f80e485a2f 548 Gene3D G3DSA:1.10.1370.30 2 548 1.2E-121 T 01-11-2018 MLA2C4_14935 b7b00914ce9b420acaeaf7f80e485a2f 548 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 3 548 7.7E-221 T 01-11-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related MLA2C4_14935 b7b00914ce9b420acaeaf7f80e485a2f 548 SUPERFAMILY SSF55486 62 518 1.47E-65 T 01-11-2018 MLA2C4_14935 b7b00914ce9b420acaeaf7f80e485a2f 548 Pfam PF01432 Peptidase family M3 155 518 4.4E-27 T 01-11-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MLA2C4_23940 eafd33e34d86593800eab262903b517d 98 Pfam PF14007 YtpI-like protein 5 90 1.2E-34 T 01-11-2018 IPR025618 YtpI-like protein MLA2C4_24395 1a97a5a6ac9bbd8520ee2cac2eab1d66 312 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 106 305 1.7E-43 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_24395 1a97a5a6ac9bbd8520ee2cac2eab1d66 312 SUPERFAMILY SSF53187 104 307 2.7E-36 T 01-11-2018 MLA2C4_24395 1a97a5a6ac9bbd8520ee2cac2eab1d66 312 SMART SM00646 186 305 4.2E-12 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_24395 1a97a5a6ac9bbd8520ee2cac2eab1d66 312 Gene3D G3DSA:3.40.630.40 103 312 7.7E-46 T 01-11-2018 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 Pfam PF07650 KH domain 37 109 1.8E-20 T 01-11-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 Gene3D G3DSA:3.30.300.20 17 106 7.4E-32 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 SMART SM00322 59 124 3.2E-7 T 01-11-2018 IPR004087 K Homology domain GO:0003676 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 SUPERFAMILY SSF54821 107 205 2.88E-37 T 01-11-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.6E-39 T 01-11-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 SUPERFAMILY SSF54814 2 105 1.6E-37 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 01-11-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 2.1E-94 T 01-11-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 Gene3D G3DSA:3.30.1140.32 107 207 2.4E-39 T 01-11-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00705 c3d5b5c1a19fbfed677affcc1946120c 219 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.308 T 01-11-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 250 2.6E-72 T 01-11-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 Gene3D G3DSA:3.30.420.40 2 251 1.6E-79 T 01-11-2018 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 SUPERFAMILY SSF53067 5 252 5.27E-69 T 01-11-2018 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 454 3.3E-36 T 01-11-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 Gene3D G3DSA:3.30.420.40 252 512 7.1E-89 T 01-11-2018 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 SUPERFAMILY SSF53067 253 501 1.24E-68 T 01-11-2018 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 6 510 4.5E-245 T 01-11-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 PIRSF PIRSF000538 4 506 1.2E-141 T 01-11-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_17715 8c5670e7194f8dddc7fe314b298abad6 513 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 01-11-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MLA2C4_18010 3e85f0fc644ded1282308d9ac2a58c68 142 SUPERFAMILY SSF53927 4 132 6.48E-25 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_18010 3e85f0fc644ded1282308d9ac2a58c68 142 Gene3D G3DSA:3.40.140.10 1 142 2.0E-31 T 01-11-2018 MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 6.6E-42 T 01-11-2018 IPR033248 Transketolase, C-terminal domain MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 SUPERFAMILY SSF52922 188 325 4.58E-41 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 6.5E-52 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 Gene3D G3DSA:3.40.50.920 193 327 1.1E-43 T 01-11-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 SMART SM00861 4 179 1.7E-69 T 01-11-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 SUPERFAMILY SSF52518 2 204 7.5E-74 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_21760 eb90277a0f6aea627771235826ab5c2c 327 Gene3D G3DSA:3.40.50.970 1 192 6.4E-92 T 01-11-2018 MLA2C4_27890 9b9ba0ebb3532ab40c384b03b5532d36 346 Gene3D G3DSA:1.20.1530.20 1 339 2.5E-28 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_27890 9b9ba0ebb3532ab40c384b03b5532d36 346 PIRSF PIRSF005508 1 346 5.8E-141 T 01-11-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MLA2C4_27890 9b9ba0ebb3532ab40c384b03b5532d36 346 Pfam PF01758 Sodium Bile acid symporter family 49 245 7.0E-67 T 01-11-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MLA2C4_27890 9b9ba0ebb3532ab40c384b03b5532d36 346 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 4 333 1.2E-142 T 01-11-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Gene3D G3DSA:3.40.50.300 246 430 3.9E-68 T 01-11-2018 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 283 296 - T 01-11-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Pfam PF02954 Bacterial regulatory protein, Fis family 536 576 1.5E-14 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SUPERFAMILY SSF55785 121 215 1.15E-7 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Gene3D G3DSA:3.30.450.20 13 109 2.5E-9 T 01-11-2018 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Gene3D G3DSA:3.30.450.20 110 222 9.1E-11 T 01-11-2018 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 559 579 1.2E-10 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 542 559 1.2E-10 T 01-11-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Pfam PF00158 Sigma-54 interaction domain 259 426 2.7E-70 T 01-11-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 346 361 - T 01-11-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Pfam PF13426 PAS domain 131 222 8.2E-4 T 01-11-2018 IPR000014 PAS domain MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Pfam PF00989 PAS fold 15 93 2.8E-6 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SMART SM00382 279 424 3.5E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 473 482 - T 01-11-2018 IPR025944 Sigma-54 interaction domain, conserved site MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SUPERFAMILY SSF55785 12 75 2.09E-8 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Gene3D G3DSA:1.10.10.60 498 579 1.1E-17 T 01-11-2018 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 Gene3D G3DSA:1.10.8.60 431 497 1.5E-19 T 01-11-2018 MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SMART SM00091 10 76 0.0012 T 01-11-2018 IPR000014 PAS domain MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SMART SM00091 120 187 4.8 T 01-11-2018 IPR000014 PAS domain MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SUPERFAMILY SSF52540 259 504 1.43E-70 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15640 2d914bac4a4c9adea1b269c733c22db2 579 SUPERFAMILY SSF46689 473 578 7.53E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 413 2.7E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 SMART SM00387 309 415 1.0E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 SUPERFAMILY SSF55874 258 415 6.02E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 Pfam PF07694 5TMR of 5TMR-LYT 22 178 3.2E-25 T 01-11-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 Gene3D G3DSA:3.30.565.10 267 412 1.3E-58 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 Gene3D G3DSA:1.10.287.130 207 266 1.3E-58 T 01-11-2018 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 SMART SM00388 203 269 8.1E-19 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 SUPERFAMILY SSF47384 199 270 3.53E-16 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 8.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 8.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 8.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 8.2E-12 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14115 61d959f85098df1beb1c53de2fe5b452 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 266 1.1E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 SUPERFAMILY SSF56801 2 509 2.09E-163 T 01-11-2018 MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 Gene3D G3DSA:3.30.300.310 410 510 6.4E-34 T 01-11-2018 MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 Gene3D G3DSA:3.40.50.12780 1 407 7.2E-129 T 01-11-2018 MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 PRINTS PR00154 AMP-binding signature 164 175 6.5E-5 T 01-11-2018 IPR020459 AMP-binding MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 PRINTS PR00154 AMP-binding signature 176 184 6.5E-5 T 01-11-2018 IPR020459 AMP-binding MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 497 6.4E-20 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_05810 e29d581acc557b1b5a33a0be4f9f763b 510 Pfam PF00501 AMP-binding enzyme 8 414 2.1E-116 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_14240 313504e9b72628774912e0b360b0c696 152 Gene3D G3DSA:3.40.630.30 48 150 3.1E-21 T 01-11-2018 MLA2C4_14240 313504e9b72628774912e0b360b0c696 152 Pfam PF00583 Acetyltransferase (GNAT) family 48 135 5.5E-12 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14240 313504e9b72628774912e0b360b0c696 152 SUPERFAMILY SSF55729 3 147 2.93E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 88 99 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 320 335 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 194 216 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 342 351 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 351 362 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 134 150 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 151 166 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 PRINTS PR00359 B-class P450 signature 292 319 1.0E-41 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 Pfam PF00067 Cytochrome P450 3 373 6.9E-38 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 01-11-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 SUPERFAMILY SSF48264 22 382 1.22E-84 T 01-11-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14050 b9eadb139f965e01820afb5abdd626bc 404 Gene3D G3DSA:1.10.630.10 4 404 3.7E-109 T 01-11-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_15380 8c780ae60f965b471a5cf66c861d8251 194 Pfam PF16107 Domain of unknown function (DUF4825) 40 131 2.5E-13 T 01-11-2018 IPR032250 Domain of unknown function DUF4825 MLA2C4_25190 5f8ecd59a63d8f9a81a851fee1dca35f 657 Pfam PF02687 FtsX-like permease family 87 172 2.4E-8 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_25190 5f8ecd59a63d8f9a81a851fee1dca35f 657 PIRSF PIRSF018968 1 655 2.0E-122 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_28120 2e4a3dd96bb0d404076f8740fa831769 273 SUPERFAMILY SSF53448 3 231 1.61E-41 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_28120 2e4a3dd96bb0d404076f8740fa831769 273 Gene3D G3DSA:3.90.550.10 1 213 3.7E-38 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_28120 2e4a3dd96bb0d404076f8740fa831769 273 Pfam PF00535 Glycosyl transferase family 2 4 121 1.8E-20 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_12165 7a3b90e8455f76f7b57d7e4887c6c77a 1029 Gene3D G3DSA:3.40.50.300 751 1028 3.1E-27 T 01-11-2018 MLA2C4_12165 7a3b90e8455f76f7b57d7e4887c6c77a 1029 SUPERFAMILY SSF52540 26 1012 1.2E-24 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12165 7a3b90e8455f76f7b57d7e4887c6c77a 1029 Gene3D G3DSA:3.40.50.300 1 323 3.3E-40 T 01-11-2018 MLA2C4_12165 7a3b90e8455f76f7b57d7e4887c6c77a 1029 Pfam PF13558 Putative exonuclease SbcCD, C subunit 924 985 2.0E-13 T 01-11-2018 MLA2C4_12165 7a3b90e8455f76f7b57d7e4887c6c77a 1029 Pfam PF13555 P-loop containing region of AAA domain 16 56 2.4E-6 T 01-11-2018 MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 Gene3D G3DSA:1.10.357.10 52 190 7.6E-20 T 01-11-2018 MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 3.2E-16 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 SUPERFAMILY SSF46689 4 77 3.2E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 SUPERFAMILY SSF48498 76 189 4.14E-14 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 Gene3D G3DSA:1.10.10.60 4 51 2.8E-17 T 01-11-2018 MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.5E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05750 4f0b789c89e1d9a321a072ed17302fc0 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.5E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_10580 c96033d9af5c73db74b067f66943e5b6 292 SUPERFAMILY SSF56112 9 274 1.22E-10 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_23220 e4b0a10e1395ac8f2a97bc8e6454d3a0 191 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 8.6E-66 T 01-11-2018 IPR003697 Maf-like protein GO:0047429 MLA2C4_23220 e4b0a10e1395ac8f2a97bc8e6454d3a0 191 Hamap MF_00528 Septum formation protein Maf [maf]. 3 188 33.669 T 01-11-2018 IPR003697 Maf-like protein GO:0047429 MLA2C4_23220 e4b0a10e1395ac8f2a97bc8e6454d3a0 191 PIRSF PIRSF006305 1 190 1.3E-64 T 01-11-2018 IPR003697 Maf-like protein GO:0047429 MLA2C4_23220 e4b0a10e1395ac8f2a97bc8e6454d3a0 191 SUPERFAMILY SSF52972 2 183 1.63E-63 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MLA2C4_23220 e4b0a10e1395ac8f2a97bc8e6454d3a0 191 Pfam PF02545 Maf-like protein 3 183 2.2E-61 T 01-11-2018 IPR003697 Maf-like protein GO:0047429 MLA2C4_23220 e4b0a10e1395ac8f2a97bc8e6454d3a0 191 Gene3D G3DSA:3.90.950.10 1 188 2.3E-75 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MLA2C4_00200 ac9e99357d1c6dbdac86b390444e2580 117 Hamap MF_01159 Initiation-control protein YabA. 1 116 24.973 T 01-11-2018 IPR010377 Initiation control protein YabA GO:0006260 MLA2C4_00200 ac9e99357d1c6dbdac86b390444e2580 117 PIRSF PIRSF021439 1 117 1.9E-42 T 01-11-2018 IPR010377 Initiation control protein YabA GO:0006260 MLA2C4_00200 ac9e99357d1c6dbdac86b390444e2580 117 Pfam PF06156 Initiation control protein YabA 2 112 1.4E-37 T 01-11-2018 IPR010377 Initiation control protein YabA GO:0006260 MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 80 6.6E-31 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 12 28 6.6E-24 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 37 52 6.6E-24 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 52 69 6.6E-24 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 Gene3D G3DSA:3.30.1340.10 1 87 5.9E-35 T 01-11-2018 IPR035895 HPr-like superfamily MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 SUPERFAMILY SSF55594 3 82 5.89E-27 T 01-11-2018 IPR035895 HPr-like superfamily MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 01-11-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 Pfam PF00381 PTS HPr component phosphorylation site 2 81 2.2E-28 T 01-11-2018 IPR000032 Phosphocarrier protein HPr-like MLA2C4_21175 48008f36b23ef60c873996270d2019b1 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 12 19 - T 01-11-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MLA2C4_11380 360c4c7d0f674eefc3eb59b16c312565 178 Pfam PF03358 NADPH-dependent FMN reductase 1 136 5.2E-32 T 01-11-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MLA2C4_11380 360c4c7d0f674eefc3eb59b16c312565 178 Gene3D G3DSA:3.40.50.360 1 169 6.3E-43 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_11380 360c4c7d0f674eefc3eb59b16c312565 178 SUPERFAMILY SSF52218 1 160 1.37E-37 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 PIRSF PIRSF001338 1 161 2.3E-68 T 01-11-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 157 2.1E-67 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 SMART SM01001 3 154 3.6E-105 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 Pfam PF00731 AIR carboxylase 5 150 2.9E-66 T 01-11-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 Gene3D G3DSA:3.40.50.7700 1 161 5.0E-76 T 01-11-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 SUPERFAMILY SSF52255 4 158 2.49E-68 T 01-11-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MLA2C4_01745 ac4cc4d397f637c3ada25c4f8cfe077a 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.345 T 01-11-2018 IPR033747 Class I PurE MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 Pfam PF00171 Aldehyde dehydrogenase family 4 427 4.5E-89 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 208 215 - T 01-11-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 Gene3D G3DSA:3.40.309.10 212 407 5.7E-174 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 236 247 - T 01-11-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 SUPERFAMILY SSF53720 4 434 3.4E-122 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 PIRSF PIRSF036492 1 455 1.7E-185 T 01-11-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 MLA2C4_06835 d2b2bac3f09bef315a69ccb84b06729a 455 Gene3D G3DSA:3.40.605.10 12 427 5.7E-174 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_25685 c0c790c39a13be08175add5bd88e337b 212 SUPERFAMILY SSF53335 22 211 8.11E-39 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_25685 c0c790c39a13be08175add5bd88e337b 212 Pfam PF01596 O-methyltransferase 18 209 9.0E-49 T 01-11-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MLA2C4_25685 c0c790c39a13be08175add5bd88e337b 212 Gene3D G3DSA:3.40.50.150 1 210 4.7E-62 T 01-11-2018 MLA2C4_19625 0316119c6b77540b95544bda3e9be843 118 Pfam PF03788 LrgA family 18 109 2.0E-23 T 01-11-2018 IPR005538 LrgA/CidA family GO:0016021 MLA2C4_19625 0316119c6b77540b95544bda3e9be843 118 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 118 22.772 T 01-11-2018 IPR023760 Holin-like protein CidA GO:0016021 MLA2C4_09720 e42f6eb725171b003445b36fb653a887 549 Gene3D G3DSA:2.60.40.10 452 537 2.6E-5 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_09720 e42f6eb725171b003445b36fb653a887 549 Pfam PF04234 CopC domain 30 127 9.7E-20 T 01-11-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MLA2C4_09720 e42f6eb725171b003445b36fb653a887 549 SUPERFAMILY SSF81296 29 127 3.64E-20 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_09720 e42f6eb725171b003445b36fb653a887 549 Pfam PF13115 YtkA-like 448 529 5.2E-14 T 01-11-2018 IPR032693 YtkA-like domain MLA2C4_09720 e42f6eb725171b003445b36fb653a887 549 Gene3D G3DSA:2.60.40.1220 30 133 9.1E-23 T 01-11-2018 MLA2C4_09720 e42f6eb725171b003445b36fb653a887 549 Pfam PF05425 Copper resistance protein D 336 426 1.4E-16 T 01-11-2018 IPR008457 Copper resistance protein D GO:0016021 MLA2C4_21065 e41a828e9942c3447b9a7b0cdea1511a 253 SUPERFAMILY SSF158560 2 74 4.32E-18 T 01-11-2018 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 151 9.3E-11 T 01-11-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 1.8E-129 T 01-11-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 Gene3D G3DSA:3.30.390.50 243 329 3.1E-30 T 01-11-2018 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 SUPERFAMILY SSF82649 243 329 1.41E-26 T 01-11-2018 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 SUPERFAMILY SSF55681 2 241 9.23E-82 T 01-11-2018 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 327 2.9E-29 T 01-11-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 MLA2C4_05800 9f6df81330ab3b08720ecaeac207d0d7 329 Gene3D G3DSA:3.30.930.10 3 242 8.0E-79 T 01-11-2018 MLA2C4_00325 0a7ffd76d5ee965197b478dc5d522a0d 102 Pfam PF07873 YabP family 19 84 2.2E-20 T 01-11-2018 IPR022476 Sporulation protein YabP/YqfC MLA2C4_00325 0a7ffd76d5ee965197b478dc5d522a0d 102 PIRSF PIRSF011576 1 102 8.2E-60 T 01-11-2018 IPR012504 Sporulation protein YabP MLA2C4_00325 0a7ffd76d5ee965197b478dc5d522a0d 102 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 19 102 1.6E-35 T 01-11-2018 IPR012504 Sporulation protein YabP MLA2C4_00325 0a7ffd76d5ee965197b478dc5d522a0d 102 Gene3D G3DSA:2.60.40.2000 27 84 1.9E-24 T 01-11-2018 IPR038705 YabP superfamily MLA2C4_00325 0a7ffd76d5ee965197b478dc5d522a0d 102 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 18 102 9.0E-43 T 01-11-2018 IPR012504 Sporulation protein YabP MLA2C4_06885 536bb69d0230a1cbf791924705fe7ef9 275 Gene3D G3DSA:3.40.33.10 13 274 3.1E-67 T 01-11-2018 IPR035940 CAP superfamily MLA2C4_06885 536bb69d0230a1cbf791924705fe7ef9 275 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 152 273 3.7E-62 T 01-11-2018 IPR014258 CAP domain, YkwD-like MLA2C4_06885 536bb69d0230a1cbf791924705fe7ef9 275 Pfam PF00188 Cysteine-rich secretory protein family 160 272 1.4E-24 T 01-11-2018 IPR014044 CAP domain MLA2C4_06885 536bb69d0230a1cbf791924705fe7ef9 275 SUPERFAMILY SSF55797 151 272 2.88E-28 T 01-11-2018 IPR035940 CAP superfamily MLA2C4_27510 9dee88e226f49d03980f1c8ac34b68ff 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 2.4E-75 T 01-11-2018 MLA2C4_27510 9dee88e226f49d03980f1c8ac34b68ff 209 Gene3D G3DSA:3.40.50.2020 1 209 5.1E-83 T 01-11-2018 MLA2C4_27510 9dee88e226f49d03980f1c8ac34b68ff 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.3E-92 T 01-11-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MLA2C4_27510 9dee88e226f49d03980f1c8ac34b68ff 209 SUPERFAMILY SSF53271 4 207 9.96E-73 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_27510 9dee88e226f49d03980f1c8ac34b68ff 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.969 T 01-11-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 282 36.17 T 01-11-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 Pfam PF08544 GHMP kinases C terminal 204 272 3.5E-8 T 01-11-2018 IPR013750 GHMP kinase, C-terminal domain MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 SUPERFAMILY SSF55060 164 284 2.05E-32 T 01-11-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 288 3.5E-109 T 01-11-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 Gene3D G3DSA:3.30.230.10 1 162 6.8E-62 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 Gene3D G3DSA:3.30.70.890 165 287 1.1E-28 T 01-11-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 Pfam PF00288 GHMP kinases N terminal domain 90 147 2.8E-13 T 01-11-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 SUPERFAMILY SSF54211 6 160 9.87E-48 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_00260 1e0ba06e2d5e5e4df189dccb1e5ae348 292 PIRSF PIRSF010376 5 290 9.8E-99 T 01-11-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MLA2C4_22520 7297a5ce3d96542c10df7e86d471e11b 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 1.1E-94 T 01-11-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MLA2C4_22520 7297a5ce3d96542c10df7e86d471e11b 312 SUPERFAMILY SSF53335 63 309 1.18E-46 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_22520 7297a5ce3d96542c10df7e86d471e11b 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 310 3.9E-106 T 01-11-2018 MLA2C4_22520 7297a5ce3d96542c10df7e86d471e11b 312 PIRSF PIRSF000401 1 312 6.5E-120 T 01-11-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MLA2C4_22520 7297a5ce3d96542c10df7e86d471e11b 312 Gene3D G3DSA:3.40.50.150 116 311 7.9E-63 T 01-11-2018 MLA2C4_22520 7297a5ce3d96542c10df7e86d471e11b 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 37.245 T 01-11-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 Pfam PF13354 Beta-lactamase enzyme family 79 284 4.7E-34 T 01-11-2018 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 SUPERFAMILY SSF56601 57 308 8.0E-74 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 01-11-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 58 82 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 227 242 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 244 259 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 129 154 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 165 189 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 89 106 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 PRINTS PR00118 Beta-lactamase class A signature 191 216 1.4E-68 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_13355 766860c3c5fcb4c4b38dfe05b2e1d848 312 Gene3D G3DSA:3.40.710.10 42 311 1.2E-82 T 01-11-2018 MLA2C4_15785 c70d92f3f6e4810abc045ced62ad16d4 794 SUPERFAMILY SSF55486 261 428 8.35E-17 T 01-11-2018 MLA2C4_15785 c70d92f3f6e4810abc045ced62ad16d4 794 Pfam PF05547 Immune inhibitor A peptidase M6 147 790 1.4E-298 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_15785 c70d92f3f6e4810abc045ced62ad16d4 794 PIRSF PIRSF007519 1 794 0.0 T 01-11-2018 IPR012300 Peptidase M6, InhA MLA2C4_15785 c70d92f3f6e4810abc045ced62ad16d4 794 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 182 491 5.1E-89 T 01-11-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 SMART SM00533 9 315 6.3E-35 T 01-11-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 SMART SM00534 328 513 2.6E-76 T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 786 2.0E-272 T 01-11-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Gene3D G3DSA:1.10.1420.10 18 281 1.3E-10 T 01-11-2018 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 SUPERFAMILY SSF48334 17 287 1.44E-30 T 01-11-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Gene3D G3DSA:3.40.50.300 293 601 2.7E-82 T 01-11-2018 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 SUPERFAMILY SSF52540 292 514 2.4E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 SMART SM00463 708 786 9.2E-19 T 01-11-2018 IPR002625 Smr domain MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 PIRSF PIRSF005814 1 786 6.5E-278 T 01-11-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 SUPERFAMILY SSF160443 709 780 1.26E-9 T 01-11-2018 IPR036063 Smr domain superfamily MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Pfam PF01713 Smr domain 711 786 1.2E-19 T 01-11-2018 IPR002625 Smr domain MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Gene3D G3DSA:1.10.1420.10 138 259 1.3E-10 T 01-11-2018 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 785 22.082 T 01-11-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Gene3D G3DSA:3.30.1370.110 699 786 1.7E-23 T 01-11-2018 MLA2C4_23650 b2b18aef26c9f860be354bb339aa54ca 786 Pfam PF00488 MutS domain V 331 512 6.1E-35 T 01-11-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 Gene3D G3DSA:1.10.287.130 251 325 2.5E-15 T 01-11-2018 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 SMART SM00387 369 481 7.3E-18 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 SUPERFAMILY SSF55874 314 480 4.71E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 SMART SM00304 184 236 1.7E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 323 2.6E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 Gene3D G3DSA:1.20.1480.50 150 243 1.3E-11 T 01-11-2018 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 SMART SM00388 258 324 6.0E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 467 7.1E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 1.2E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 1.2E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 1.2E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 Gene3D G3DSA:3.30.565.10 329 481 5.1E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 SUPERFAMILY SSF47384 244 324 6.08E-14 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 SUPERFAMILY SSF158472 184 233 9.94E-10 T 01-11-2018 MLA2C4_14440 4afbd630aca018556ced1a232547f56e 481 Pfam PF00672 HAMP domain 184 233 7.2E-9 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_19600 53e4bba3506f73219a99aa84b6277561 328 Pfam PF02719 Polysaccharide biosynthesis protein 6 279 8.1E-106 T 01-11-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MLA2C4_19600 53e4bba3506f73219a99aa84b6277561 328 Gene3D G3DSA:3.90.25.30 164 318 7.9E-121 T 01-11-2018 MLA2C4_19600 53e4bba3506f73219a99aa84b6277561 328 Gene3D G3DSA:3.40.50.720 3 306 7.9E-121 T 01-11-2018 MLA2C4_19600 53e4bba3506f73219a99aa84b6277561 328 SUPERFAMILY SSF51735 1 258 2.59E-57 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_01215 5b295294fa7c089e68674658ea2914c8 278 PIRSF PIRSF006483 1 278 2.8E-88 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_01215 5b295294fa7c089e68674658ea2914c8 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 212 7.6E-65 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_01215 5b295294fa7c089e68674658ea2914c8 278 Gene3D G3DSA:3.30.70.120 189 265 1.7E-25 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_01215 5b295294fa7c089e68674658ea2914c8 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 272 1.7E-22 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_03595 7bb24003ded5eabc6d368a4142483289 270 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 270 17.3 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_03595 7bb24003ded5eabc6d368a4142483289 270 Pfam PF02673 Bacitracin resistance protein BacA 11 265 4.6E-76 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_05425 64392a73252120f590b10f019119c70d 314 Pfam PF01966 HD domain 161 278 2.0E-10 T 01-11-2018 IPR006674 HD domain MLA2C4_05425 64392a73252120f590b10f019119c70d 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 61.913 T 01-11-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 MLA2C4_05425 64392a73252120f590b10f019119c70d 314 SMART SM00471 156 288 2.3E-6 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_05425 64392a73252120f590b10f019119c70d 314 Gene3D G3DSA:1.10.3210.10 121 297 8.5E-12 T 01-11-2018 MLA2C4_05425 64392a73252120f590b10f019119c70d 314 SUPERFAMILY SSF109604 137 280 7.99E-16 T 01-11-2018 MLA2C4_05425 64392a73252120f590b10f019119c70d 314 Pfam PF01336 OB-fold nucleic acid binding domain 28 89 2.4E-6 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MLA2C4_05425 64392a73252120f590b10f019119c70d 314 Gene3D G3DSA:2.40.50.140 13 101 1.5E-5 T 01-11-2018 MLA2C4_05425 64392a73252120f590b10f019119c70d 314 SUPERFAMILY SSF50249 31 92 3.03E-5 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_04685 5031202f9b6d4feb1647b032ea1edffb 486 SUPERFAMILY SSF56059 214 420 5.74E-12 T 01-11-2018 MLA2C4_04685 5031202f9b6d4feb1647b032ea1edffb 486 Pfam PF14398 YheC/D like ATP-grasp 188 442 1.4E-83 T 01-11-2018 IPR026838 Endospore coat-associated protein YheC/D MLA2C4_04685 5031202f9b6d4feb1647b032ea1edffb 486 Gene3D G3DSA:3.30.470.20 311 435 1.2E-6 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 307 1.5E-59 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 434 1.0E-14 T 01-11-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 SUPERFAMILY SSF51905 1 319 7.08E-43 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 Gene3D G3DSA:3.40.250.10 453 554 1.1E-25 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 4 443 6.4E-196 T 01-11-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 Gene3D G3DSA:3.50.50.60 116 439 2.3E-183 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 Gene3D G3DSA:3.50.50.60 4 324 2.3E-183 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 Pfam PF00581 Rhodanese-like domain 463 544 5.1E-9 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 2.9E-14 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 2.9E-14 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.9E-14 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 2.9E-14 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 SMART SM00450 454 550 8.2E-15 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 1.1E-22 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.1E-22 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.1E-22 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.1E-22 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-22 T 01-11-2018 MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 SUPERFAMILY SSF52821 437 544 3.29E-24 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04265 57388d7f840b022034b4155e55ccbdf6 554 SUPERFAMILY SSF55424 326 448 5.33E-33 T 01-11-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Gene3D G3DSA:1.20.1270.10 477 578 1.1E-23 T 01-11-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 SUPERFAMILY SSF100920 354 510 2.88E-60 T 01-11-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Gene3D G3DSA:3.30.420.40 158 337 2.1E-151 T 01-11-2018 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 607 36.833 T 01-11-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 SUPERFAMILY SSF100934 477 575 5.36E-11 T 01-11-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Gene3D G3DSA:3.90.640.10 198 279 2.1E-151 T 01-11-2018 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Gene3D G3DSA:2.60.34.10 348 476 3.4E-57 T 01-11-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 2.8E-281 T 01-11-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.3E-80 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Gene3D G3DSA:3.30.420.40 5 346 2.1E-151 T 01-11-2018 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 SUPERFAMILY SSF53067 161 352 2.22E-66 T 01-11-2018 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 01-11-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 Pfam PF00012 Hsp70 protein 76 573 1.1E-216 T 01-11-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MLA2C4_22530 d6649b88264b036bf07eb1b444edc687 611 SUPERFAMILY SSF53067 1 157 6.31E-58 T 01-11-2018 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 3.1E-65 T 01-11-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.208 T 01-11-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 Pfam PF00467 KOW motif 129 158 4.0E-5 T 01-11-2018 IPR005824 KOW MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 01-11-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 Gene3D G3DSA:3.30.70.940 1 118 2.4E-44 T 01-11-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.1E-20 T 01-11-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.1E-20 T 01-11-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.1E-20 T 01-11-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 Pfam PF02357 Transcription termination factor nusG 3 109 1.0E-28 T 01-11-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 Gene3D G3DSA:2.30.30.30 119 177 9.8E-24 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 SMART SM00738 2 113 4.4E-51 T 01-11-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 SUPERFAMILY SSF50104 121 177 1.35E-18 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily MLA2C4_00600 e624392e043dda55457abed19b2a25d8 177 SUPERFAMILY SSF82679 2 114 3.53E-40 T 01-11-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MLA2C4_11115 ad98cff0548584657011e89dd49d1a6c 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 379 2.7E-126 T 01-11-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MLA2C4_11115 ad98cff0548584657011e89dd49d1a6c 400 Gene3D G3DSA:1.20.1090.10 187 389 1.8E-64 T 01-11-2018 MLA2C4_11115 ad98cff0548584657011e89dd49d1a6c 400 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MLA2C4_11115 ad98cff0548584657011e89dd49d1a6c 400 Gene3D G3DSA:3.40.50.1970 1 185 2.6E-62 T 01-11-2018 MLA2C4_11115 ad98cff0548584657011e89dd49d1a6c 400 SUPERFAMILY SSF56796 5 388 7.59E-125 T 01-11-2018 MLA2C4_16650 7f038a19c00bb0bd67636c103fd20e2a 874 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 30 860 5.2E-271 T 01-11-2018 IPR018752 Uncharacterised protein family UPF0753 MLA2C4_16650 7f038a19c00bb0bd67636c103fd20e2a 874 Hamap MF_01871 UPF0753 protein . 25 874 24.341 T 01-11-2018 IPR018752 Uncharacterised protein family UPF0753 MLA2C4_25210 325889b429a8ab2069a698d493a2b7d4 338 Gene3D G3DSA:3.40.1190.20 2 338 5.9E-100 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_25210 325889b429a8ab2069a698d493a2b7d4 338 SUPERFAMILY SSF53613 1 328 7.48E-62 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_25210 325889b429a8ab2069a698d493a2b7d4 338 Pfam PF00294 pfkB family carbohydrate kinase 3 317 1.4E-31 T 01-11-2018 IPR011611 Carbohydrate kinase PfkB MLA2C4_10845 8267ac4f49282dc59f09f9018386ced9 90 Gene3D G3DSA:3.30.110.20 1 88 1.1E-33 T 01-11-2018 IPR036882 Alba-like domain superfamily GO:0003676 MLA2C4_10845 8267ac4f49282dc59f09f9018386ced9 90 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 4 87 1.0E-39 T 01-11-2018 IPR007347 Sporulation stage V, protein S MLA2C4_10845 8267ac4f49282dc59f09f9018386ced9 90 Pfam PF04232 Stage V sporulation protein S (SpoVS) 4 84 8.2E-39 T 01-11-2018 IPR007347 Sporulation stage V, protein S MLA2C4_15955 28db7c980ac72547d206761497121961 647 Pfam PF03764 Elongation factor G, domain IV 445 538 2.0E-12 T 01-11-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 Gene3D G3DSA:3.30.70.870 348 421 1.6E-7 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 Gene3D G3DSA:3.30.70.240 544 614 2.8E-19 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 SMART SM00889 423 538 1.2E-5 T 01-11-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 SUPERFAMILY SSF50447 226 339 5.59E-20 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_15955 28db7c980ac72547d206761497121961 647 Pfam PF14492 Elongation Factor G, domain II 347 420 1.1E-7 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 Gene3D G3DSA:3.40.50.300 1 252 4.6E-79 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 Gene3D G3DSA:3.30.230.10 448 616 2.8E-19 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_15955 28db7c980ac72547d206761497121961 647 SUPERFAMILY SSF52540 4 242 8.28E-76 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15955 28db7c980ac72547d206761497121961 647 Pfam PF00679 Elongation factor G C-terminus 541 620 9.5E-10 T 01-11-2018 IPR000640 Elongation factor EFG, domain V-like MLA2C4_15955 28db7c980ac72547d206761497121961 647 Gene3D G3DSA:2.40.30.10 253 347 1.2E-14 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 SUPERFAMILY SSF54980 541 620 6.23E-9 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_15955 28db7c980ac72547d206761497121961 647 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 154 2.0E-34 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 SUPERFAMILY SSF54211 444 538 1.1E-12 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.0E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.0E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.0E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.0E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.0E-16 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 SUPERFAMILY SSF54980 347 424 1.69E-12 T 01-11-2018 IPR035647 EF-G domain III/V-like MLA2C4_15955 28db7c980ac72547d206761497121961 647 Pfam PF00009 Elongation factor Tu GTP binding domain 3 242 5.7E-61 T 01-11-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MLA2C4_15955 28db7c980ac72547d206761497121961 647 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 01-11-2018 IPR031157 Tr-type G domain, conserved site MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 476 498 3.8E-36 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 510 527 3.8E-36 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 270 296 3.8E-36 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 3.8E-36 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 216 238 3.8E-36 T 01-11-2018 MLA2C4_15955 28db7c980ac72547d206761497121961 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 461 475 3.8E-36 T 01-11-2018 MLA2C4_20190 8cfb83814430fd1b5934713fca0fb9d6 250 SMART SM00332 1 240 1.3E-22 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_20190 8cfb83814430fd1b5934713fca0fb9d6 250 Gene3D G3DSA:3.60.40.10 1 243 2.9E-70 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_20190 8cfb83814430fd1b5934713fca0fb9d6 250 SUPERFAMILY SSF81606 2 241 4.84E-64 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_20190 8cfb83814430fd1b5934713fca0fb9d6 250 SMART SM00331 7 242 1.7E-43 T 01-11-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_20190 8cfb83814430fd1b5934713fca0fb9d6 250 Pfam PF13672 Protein phosphatase 2C 12 204 2.9E-21 T 01-11-2018 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Gene3D G3DSA:3.30.310.50 370 448 8.8E-31 T 01-11-2018 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 1.9E-15 T 01-11-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 1.5E-35 T 01-11-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 2.6E-43 T 01-11-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 SUPERFAMILY SSF55957 357 446 1.31E-26 T 01-11-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 SUPERFAMILY SSF53738 257 365 1.88E-33 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.545 T 01-11-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 SUPERFAMILY SSF53738 3 180 4.71E-46 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Gene3D G3DSA:3.40.120.10 256 339 1.9E-74 T 01-11-2018 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.3E-12 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 2.3E-12 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 2.3E-12 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Gene3D G3DSA:3.40.120.10 3 155 5.9E-62 T 01-11-2018 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 6.2E-16 T 01-11-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 SUPERFAMILY SSF53738 158 256 6.28E-26 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.5E-188 T 01-11-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 Gene3D G3DSA:3.40.120.10 173 362 1.9E-74 T 01-11-2018 MLA2C4_00965 2c6fe3076c56d86e2bed790a7cede559 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 01-11-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_26460 96540d506adec48a533718c4c8011193 143 SUPERFAMILY SSF54909 70 141 1.29E-12 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_26460 96540d506adec48a533718c4c8011193 143 SUPERFAMILY SSF46785 6 67 2.28E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26460 96540d506adec48a533718c4c8011193 143 Gene3D G3DSA:1.10.10.10 5 57 4.3E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26460 96540d506adec48a533718c4c8011193 143 Pfam PF01037 Lrp/AsnC ligand binding domain 82 128 6.3E-9 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_26460 96540d506adec48a533718c4c8011193 143 Gene3D G3DSA:3.30.70.920 58 143 6.8E-17 T 01-11-2018 MLA2C4_26460 96540d506adec48a533718c4c8011193 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 7.4E-10 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_26460 96540d506adec48a533718c4c8011193 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 7.4E-10 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_26460 96540d506adec48a533718c4c8011193 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 7.4E-10 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_26460 96540d506adec48a533718c4c8011193 143 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 8.3E-13 T 01-11-2018 MLA2C4_26460 96540d506adec48a533718c4c8011193 143 SMART SM00344 8 114 4.6E-28 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_20705 24449481e848fb9894bfad374df9a7a6 42 Pfam PF13790 SR1 protein 1 38 1.4E-16 T 01-11-2018 IPR025236 SR1 protein MLA2C4_05690 6d0601b94db66db4c9b52ee61be509a6 472 PIRSF PIRSF026631 1 472 8.9E-141 T 01-11-2018 IPR014529 Uncharacterised conserved protein UCP026631 MLA2C4_05690 6d0601b94db66db4c9b52ee61be509a6 472 Pfam PF03703 Bacterial PH domain 391 464 9.0E-11 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_05690 6d0601b94db66db4c9b52ee61be509a6 472 Pfam PF03703 Bacterial PH domain 238 321 2.7E-12 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_05690 6d0601b94db66db4c9b52ee61be509a6 472 Pfam PF03703 Bacterial PH domain 59 136 9.5E-16 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_12265 6b7ebe4ae5d66cff39f08c82840144e5 206 SUPERFAMILY SSF54909 107 181 8.78E-10 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_12265 6b7ebe4ae5d66cff39f08c82840144e5 206 Pfam PF16291 Domain of unknown function (DUF4937 2 87 1.6E-33 T 01-11-2018 IPR032555 Domain of unknown function DUF4937 MLA2C4_12265 6b7ebe4ae5d66cff39f08c82840144e5 206 SUPERFAMILY SSF54909 1 93 1.86E-14 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_12265 6b7ebe4ae5d66cff39f08c82840144e5 206 Gene3D G3DSA:3.30.70.100 40 175 1.4E-10 T 01-11-2018 MLA2C4_22690 2395fb5fcffd6c934109ac72689d0d76 277 Pfam PF13673 Acetyltransferase (GNAT) domain 42 123 3.7E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_22690 2395fb5fcffd6c934109ac72689d0d76 277 Gene3D G3DSA:3.40.630.30 5 163 4.4E-16 T 01-11-2018 MLA2C4_22690 2395fb5fcffd6c934109ac72689d0d76 277 SUPERFAMILY SSF55729 5 256 1.36E-31 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_02520 96ad6f0e6ef86532c17846b23ae8e779 375 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 370 4.2E-192 T 01-11-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB MLA2C4_02520 96ad6f0e6ef86532c17846b23ae8e779 375 Gene3D G3DSA:3.20.20.70 28 341 5.7E-22 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_02520 96ad6f0e6ef86532c17846b23ae8e779 375 Pfam PF13353 4Fe-4S single cluster domain 41 119 8.9E-7 T 01-11-2018 MLA2C4_02520 96ad6f0e6ef86532c17846b23ae8e779 375 SUPERFAMILY SSF102114 34 329 9.03E-26 T 01-11-2018 MLA2C4_02520 96ad6f0e6ef86532c17846b23ae8e779 375 Pfam PF08756 YfkB-like domain 221 370 7.0E-75 T 01-11-2018 IPR014866 YfkB-like domain MLA2C4_02520 96ad6f0e6ef86532c17846b23ae8e779 375 Pfam PF04055 Radical SAM superfamily 37 175 1.7E-10 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_22465 5beafefb33939a5bc06e187b25725ebd 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 2.5E-48 T 01-11-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 MLA2C4_22465 5beafefb33939a5bc06e187b25725ebd 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 98 8.3E-17 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MLA2C4_22465 5beafefb33939a5bc06e187b25725ebd 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_22465 5beafefb33939a5bc06e187b25725ebd 132 Gene3D G3DSA:3.40.140.10 1 132 8.9E-63 T 01-11-2018 MLA2C4_22465 5beafefb33939a5bc06e187b25725ebd 132 SUPERFAMILY SSF53927 3 130 4.35E-49 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 SMART SM00388 234 300 3.5E-18 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 Gene3D G3DSA:1.20.1480.50 146 233 1.0E-17 T 01-11-2018 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 SMART SM00387 345 457 4.1E-40 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 Gene3D G3DSA:1.10.287.130 234 298 1.1E-18 T 01-11-2018 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 SMART SM00304 181 233 8.9E-9 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 SUPERFAMILY SSF47384 218 301 1.94E-18 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 1.0E-16 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.0E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.0E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 1.0E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 1.0E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 SUPERFAMILY SSF158472 181 229 1.57E-10 T 01-11-2018 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 Gene3D G3DSA:3.30.565.10 299 460 8.1E-47 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 Pfam PF00672 HAMP domain 181 228 1.0E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 SUPERFAMILY SSF55874 290 455 8.64E-48 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03435 818a8794eb3bfa4a03a5e3f6694f9c90 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 454 1.9E-30 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05530 3fbc9155201b012b848fb096eeb1d77a 135 Pfam PF03551 Transcriptional regulator PadR-like family 48 116 3.8E-15 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_05530 3fbc9155201b012b848fb096eeb1d77a 135 SUPERFAMILY SSF46785 44 123 2.55E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05530 3fbc9155201b012b848fb096eeb1d77a 135 Gene3D G3DSA:1.10.10.10 23 135 9.0E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 SUPERFAMILY SSF52518 14 192 2.27E-62 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 206 340 8.8E-43 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 Gene3D G3DSA:3.40.50.970 8 191 1.5E-73 T 01-11-2018 MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 17 566 7.9E-251 T 01-11-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 SUPERFAMILY SSF52518 373 566 7.04E-69 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 SUPERFAMILY SSF52467 201 365 1.0E-60 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 17 182 1.7E-58 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 Gene3D G3DSA:3.40.50.970 365 571 2.1E-70 T 01-11-2018 MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 543 7.6E-52 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_09445 7fabf907e9f0a907f87a7bf245365e0a 571 Gene3D G3DSA:3.40.50.1220 200 363 3.5E-60 T 01-11-2018 MLA2C4_06875 2e3436251db79d33f94b829066f9a48b 307 Pfam PF00849 RNA pseudouridylate synthase 93 245 4.1E-32 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06875 2e3436251db79d33f94b829066f9a48b 307 SUPERFAMILY SSF55120 78 301 4.8E-64 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06875 2e3436251db79d33f94b829066f9a48b 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 301 1.1E-73 T 01-11-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06875 2e3436251db79d33f94b829066f9a48b 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 01-11-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_06875 2e3436251db79d33f94b829066f9a48b 307 Gene3D G3DSA:3.30.2350.10 85 306 6.4E-63 T 01-11-2018 MLA2C4_00415 7da2806ac119c5b6fb0430a9e32a818c 171 SUPERFAMILY SSF55083 4 149 1.18E-53 T 01-11-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MLA2C4_00415 7da2806ac119c5b6fb0430a9e32a818c 171 Gene3D G3DSA:3.30.70.560 2 170 4.5E-58 T 01-11-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MLA2C4_00415 7da2806ac119c5b6fb0430a9e32a818c 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 5.1E-48 T 01-11-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MLA2C4_00415 7da2806ac119c5b6fb0430a9e32a818c 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 01-11-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MLA2C4_00415 7da2806ac119c5b6fb0430a9e32a818c 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 6.9E-40 T 01-11-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MLA2C4_19450 93fc86e55ec5471576c3d9a12eec0a57 360 ProSitePatterns PS01095 Chitinases family 18 active site. 137 145 - T 01-11-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MLA2C4_19450 93fc86e55ec5471576c3d9a12eec0a57 360 SUPERFAMILY SSF51445 33 347 9.04E-58 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_19450 93fc86e55ec5471576c3d9a12eec0a57 360 SMART SM00636 34 338 4.6E-7 T 01-11-2018 IPR011583 Chitinase II GO:0008061 MLA2C4_19450 93fc86e55ec5471576c3d9a12eec0a57 360 Pfam PF00704 Glycosyl hydrolases family 18 36 338 1.1E-28 T 01-11-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 MLA2C4_19450 93fc86e55ec5471576c3d9a12eec0a57 360 Gene3D G3DSA:3.20.20.80 28 360 4.5E-109 T 01-11-2018 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 Gene3D G3DSA:3.40.710.10 30 307 1.4E-91 T 01-11-2018 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 307 409 5.2E-13 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 SUPERFAMILY SSF69189 299 388 1.96E-16 T 01-11-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 Gene3D G3DSA:2.60.410.10 308 409 5.9E-14 T 01-11-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 SUPERFAMILY SSF56601 4 307 5.31E-80 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 SMART SM00936 307 409 1.3E-13 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 4.0E-13 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 4.0E-13 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 4.0E-13 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_13315 7696ed604c6a42d2df0a3bcc96fa5357 437 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 36 287 2.1E-85 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 Gene3D G3DSA:3.90.180.10 4 364 1.7E-125 T 01-11-2018 MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 7.7E-11 T 01-11-2018 IPR027399 Alcohol dehydrogenase GroES-associated MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 SUPERFAMILY SSF50129 1 176 8.37E-61 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 01-11-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 Gene3D G3DSA:3.40.50.720 168 337 1.7E-125 T 01-11-2018 MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 SUPERFAMILY SSF51735 155 339 2.63E-49 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 3.1E-30 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_16335 9567ff9f2407e53f5df5fe3fc06f5d5a 377 Pfam PF00107 Zinc-binding dehydrogenase 188 255 3.1E-10 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 01-11-2018 IPR019926 Ribosomal protein L3, conserved site MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.709 T 01-11-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 SUPERFAMILY SSF50447 1 208 4.15E-83 T 01-11-2018 IPR009000 Translation protein, beta-barrel domain superfamily MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 Gene3D G3DSA:2.40.50.620 33 97 4.7E-16 T 01-11-2018 MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 Gene3D G3DSA:2.40.30.10 133 209 1.2E-17 T 01-11-2018 MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 Pfam PF00297 Ribosomal protein L3 99 181 1.9E-17 T 01-11-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00675 ec879859a6ca8ca9fa4844a9f1adb622 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 7.4E-89 T 01-11-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 Pfam PF13541 Subunit ChlI of Mg-chelatase 363 430 1.4E-8 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 45.42 T 01-11-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 SUPERFAMILY SSF54211 255 456 5.69E-44 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 SUPERFAMILY SSF52540 68 293 5.24E-50 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 Gene3D G3DSA:3.30.230.10 284 457 1.0E-20 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 Pfam PF13481 AAA domain 60 222 1.7E-17 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 SMART SM00382 90 244 1.5E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 Gene3D G3DSA:3.40.50.300 64 283 4.2E-44 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 8.8E-212 T 01-11-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 322 345 6.2E-94 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 82 110 6.2E-94 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 213 241 6.2E-94 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 248 274 6.2E-94 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 10 34 6.2E-94 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 124 141 6.2E-94 T 01-11-2018 MLA2C4_00530 c3e7b930479d3ddc00d90219f01c0911 458 PRINTS PR01874 DNA repair protein radA signature 174 198 6.2E-94 T 01-11-2018 MLA2C4_22675 76c6f82a121b3cc44cda563c91b0e62f 216 Gene3D G3DSA:1.10.287.860 156 208 6.4E-22 T 01-11-2018 MLA2C4_22675 76c6f82a121b3cc44cda563c91b0e62f 216 Gene3D G3DSA:3.30.460.10 1 155 4.0E-49 T 01-11-2018 MLA2C4_22675 76c6f82a121b3cc44cda563c91b0e62f 216 SUPERFAMILY SSF81301 11 202 4.74E-56 T 01-11-2018 MLA2C4_22675 76c6f82a121b3cc44cda563c91b0e62f 216 SMART SM00954 50 173 8.2E-46 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_22675 76c6f82a121b3cc44cda563c91b0e62f 216 Pfam PF04607 Region found in RelA / SpoT proteins 50 171 5.0E-38 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_21120 80a1321b81db3f6ffe5678584d128860 212 SMART SM01007 9 195 3.1E-39 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal MLA2C4_21120 80a1321b81db3f6ffe5678584d128860 212 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 11 199 4.6E-62 T 01-11-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 MLA2C4_21120 80a1321b81db3f6ffe5678584d128860 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 193 1.0E-38 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal MLA2C4_21120 80a1321b81db3f6ffe5678584d128860 212 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 203 99.773 T 01-11-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 MLA2C4_21120 80a1321b81db3f6ffe5678584d128860 212 SUPERFAMILY SSF53639 5 201 5.49E-44 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MLA2C4_21120 80a1321b81db3f6ffe5678584d128860 212 Gene3D G3DSA:3.40.225.10 7 206 6.0E-48 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 359 43.977 T 01-11-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 361 4.5E-134 T 01-11-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 SUPERFAMILY SSF56059 106 304 5.13E-65 T 01-11-2018 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 Gene3D G3DSA:3.40.50.20 1 115 8.4E-51 T 01-11-2018 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 SUPERFAMILY SSF52440 8 93 1.87E-27 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 Pfam PF02222 ATP-grasp domain 115 284 4.1E-61 T 01-11-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 6 74 3.0E-6 T 01-11-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 Gene3D G3DSA:3.30.470.20 185 374 1.9E-85 T 01-11-2018 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 Gene3D G3DSA:3.30.1490.20 116 184 4.4E-30 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_01750 5ac4ad5e84b48019ad63f425abbc2d9f 383 SUPERFAMILY SSF51246 308 376 9.42E-17 T 01-11-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MLA2C4_04085 599cd77cca75a4b9d50680db8de7739d 82 Pfam PF14148 YhdB-like protein 3 71 3.1E-37 T 01-11-2018 IPR025431 YhdB-like protein MLA2C4_11475 0345aa42137e1b10eb2312de5fabdc53 220 Pfam PF01144 Coenzyme A transferase 10 202 3.5E-36 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MLA2C4_11475 0345aa42137e1b10eb2312de5fabdc53 220 Gene3D G3DSA:3.40.1080.10 5 217 2.4E-89 T 01-11-2018 MLA2C4_11475 0345aa42137e1b10eb2312de5fabdc53 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 212 2.1E-98 T 01-11-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MLA2C4_11475 0345aa42137e1b10eb2312de5fabdc53 220 SMART SM00882 9 205 3.3E-61 T 01-11-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MLA2C4_11475 0345aa42137e1b10eb2312de5fabdc53 220 SUPERFAMILY SSF100950 6 215 6.98E-67 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 Gene3D G3DSA:2.70.240.10 29 317 5.8E-96 T 01-11-2018 MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 SUPERFAMILY SSF56959 36 326 4.58E-91 T 01-11-2018 IPR036435 Leukocidin/porin MspA superfamily MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 Pfam PF07968 Leukocidin/Hemolysin toxin family 62 313 1.7E-77 T 01-11-2018 IPR016183 Leukocidin/Hemolysin toxin GO:0005576|GO:0051715 MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 66 85 1.3E-5 T 01-11-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 126 147 1.3E-5 T 01-11-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 249 266 1.3E-5 T 01-11-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 MLA2C4_18270 58e7c8cee86ea16dff4b15e25ba30a25 412 TIGRFAM TIGR01002 hlyII: beta-channel forming cytolysin 5 318 8.4E-124 T 01-11-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 MLA2C4_11220 d2ef7f0275250764c98989d6340c6e7a 218 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 14 214 5.9E-74 T 01-11-2018 IPR005744 Hly-III GO:0016021|GO:0019835 MLA2C4_11220 d2ef7f0275250764c98989d6340c6e7a 218 Pfam PF03006 Haemolysin-III related 13 206 1.8E-42 T 01-11-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MLA2C4_01960 0a4969c6fbaa048eb834fc30035bd2db 367 Pfam PF01522 Polysaccharide deacetylase 203 324 1.6E-15 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_01960 0a4969c6fbaa048eb834fc30035bd2db 367 Gene3D G3DSA:2.60.40.3760 50 146 1.5E-37 T 01-11-2018 MLA2C4_01960 0a4969c6fbaa048eb834fc30035bd2db 367 Gene3D G3DSA:3.20.20.370 147 367 1.2E-58 T 01-11-2018 MLA2C4_01960 0a4969c6fbaa048eb834fc30035bd2db 367 SUPERFAMILY SSF88713 169 344 6.12E-27 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_21235 67acb92ce97c4769741b6a08f7cacb7f 172 Gene3D G3DSA:1.20.58.500 4 100 4.6E-15 T 01-11-2018 MLA2C4_21235 67acb92ce97c4769741b6a08f7cacb7f 172 Pfam PF03745 Domain of unknown function (DUF309) 6 66 3.6E-22 T 01-11-2018 IPR005500 Protein of unknown function DUF309 MLA2C4_21235 67acb92ce97c4769741b6a08f7cacb7f 172 SUPERFAMILY SSF140663 1 129 3.4E-36 T 01-11-2018 IPR023203 TTHA0068-like superfamily MLA2C4_17530 70c490b42f8c0bb13012f2882a7810ea 126 SUPERFAMILY SSF54593 1 125 8.32E-27 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_17530 70c490b42f8c0bb13012f2882a7810ea 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 2.8E-15 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_17530 70c490b42f8c0bb13012f2882a7810ea 126 Gene3D G3DSA:3.10.180.10 1 126 2.8E-37 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_24370 5eb1f56fc36d22dc1c61ebb0904ba033 114 Pfam PF03551 Transcriptional regulator PadR-like family 20 90 5.2E-22 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_24370 5eb1f56fc36d22dc1c61ebb0904ba033 114 SUPERFAMILY SSF46785 4 99 7.55E-25 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_24370 5eb1f56fc36d22dc1c61ebb0904ba033 114 Gene3D G3DSA:1.10.10.10 6 114 1.7E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14170 5c8f6ca6c34a84be92e0904110ae2b54 268 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 268 4.2E-53 T 01-11-2018 IPR003797 DegV MLA2C4_14170 5c8f6ca6c34a84be92e0904110ae2b54 268 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 7 268 1.1E-57 T 01-11-2018 IPR003797 DegV MLA2C4_14170 5c8f6ca6c34a84be92e0904110ae2b54 268 SUPERFAMILY SSF82549 1 268 3.14E-62 T 01-11-2018 MLA2C4_14170 5c8f6ca6c34a84be92e0904110ae2b54 268 Gene3D G3DSA:3.40.50.10170 1 147 2.1E-32 T 01-11-2018 MLA2C4_14170 5c8f6ca6c34a84be92e0904110ae2b54 268 Gene3D G3DSA:3.30.1180.10 149 268 1.4E-21 T 01-11-2018 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 Gene3D G3DSA:3.40.440.10 5 252 7.4E-109 T 01-11-2018 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 01-11-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.0E-184 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 SMART SM00788 3 422 2.0E-293 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 01-11-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 SUPERFAMILY SSF52540 1 427 2.23E-176 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 2.3E-192 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 Gene3D G3DSA:3.90.170.10 265 429 1.2E-71 T 01-11-2018 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 211.05 T 01-11-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MLA2C4_28375 0593a8c95d3b89fb42296ffd98a065c7 429 Gene3D G3DSA:1.10.300.10 100 199 7.4E-109 T 01-11-2018 MLA2C4_01700 ed7c814bfb8a32dfa8a7c3f1dc61c1c9 319 Pfam PF01619 Proline dehydrogenase 55 296 1.1E-16 T 01-11-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MLA2C4_01700 ed7c814bfb8a32dfa8a7c3f1dc61c1c9 319 SUPERFAMILY SSF51730 45 304 1.29E-54 T 01-11-2018 IPR029041 FAD-linked oxidoreductase-like MLA2C4_01700 ed7c814bfb8a32dfa8a7c3f1dc61c1c9 319 Gene3D G3DSA:3.20.20.530 28 309 3.4E-65 T 01-11-2018 MLA2C4_01700 ed7c814bfb8a32dfa8a7c3f1dc61c1c9 319 PIRSF PIRSF000196 9 310 2.4E-99 T 01-11-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 MLA2C4_26105 2df557d2a77247831310cde5a1fbb0ab 126 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 21 123 3.0E-52 T 01-11-2018 MLA2C4_16535 17a9403f1d5292792fd1ab99125b25b4 99 Pfam PF01022 Bacterial regulatory protein, arsR family 26 66 1.4E-11 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_16535 17a9403f1d5292792fd1ab99125b25b4 99 SUPERFAMILY SSF46785 14 85 8.67E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_16535 17a9403f1d5292792fd1ab99125b25b4 99 Gene3D G3DSA:1.10.10.10 4 98 5.0E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16535 17a9403f1d5292792fd1ab99125b25b4 99 SMART SM00418 19 97 1.1E-19 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 SUPERFAMILY SSF56601 1 287 4.39E-85 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 Gene3D G3DSA:2.60.410.10 287 377 1.5E-19 T 01-11-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 SMART SM00936 287 378 2.7E-21 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 Gene3D G3DSA:3.40.710.10 17 285 7.1E-99 T 01-11-2018 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 287 377 5.7E-20 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 1.3E-17 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 1.3E-17 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.3E-17 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 267 4.8E-90 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_21325 77568c9bdb5f2a6672bb3d236a0a9522 396 SUPERFAMILY SSF69189 279 376 2.94E-20 T 01-11-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_22605 642baf6bc95a9e7b48170f541b5ddfaf 249 Pfam PF13649 Methyltransferase domain 40 135 3.6E-19 T 01-11-2018 MLA2C4_22605 642baf6bc95a9e7b48170f541b5ddfaf 249 SUPERFAMILY SSF53335 3 247 6.96E-53 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_22605 642baf6bc95a9e7b48170f541b5ddfaf 249 Gene3D G3DSA:2.20.25.110 143 206 1.1E-87 T 01-11-2018 MLA2C4_22605 642baf6bc95a9e7b48170f541b5ddfaf 249 Gene3D G3DSA:3.40.50.150 5 245 1.1E-87 T 01-11-2018 MLA2C4_15825 252d1aca7e3596ffb0c0c0fe9c3e3dff 244 Gene3D G3DSA:3.40.50.2300 1 138 4.0E-39 T 01-11-2018 MLA2C4_15825 252d1aca7e3596ffb0c0c0fe9c3e3dff 244 SUPERFAMILY SSF52172 1 176 3.42E-6 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_15825 252d1aca7e3596ffb0c0c0fe9c3e3dff 244 Pfam PF00072 Response regulator receiver domain 3 114 2.2E-8 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_15825 252d1aca7e3596ffb0c0c0fe9c3e3dff 244 SMART SM00850 148 241 2.2E-18 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_15825 252d1aca7e3596ffb0c0c0fe9c3e3dff 244 Pfam PF04397 LytTr DNA-binding domain 150 240 6.7E-20 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_15825 252d1aca7e3596ffb0c0c0fe9c3e3dff 244 Gene3D G3DSA:2.40.50.1020 139 244 1.8E-28 T 01-11-2018 MLA2C4_24275 aab32f28c4571fa291067919a015563d 308 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 4.2E-26 T 01-11-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MLA2C4_24275 aab32f28c4571fa291067919a015563d 308 SUPERFAMILY SSF51735 4 138 5.31E-40 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_24275 aab32f28c4571fa291067919a015563d 308 Gene3D G3DSA:3.40.50.720 1 120 4.6E-31 T 01-11-2018 MLA2C4_24275 aab32f28c4571fa291067919a015563d 308 SUPERFAMILY SSF55347 126 266 2.45E-42 T 01-11-2018 MLA2C4_24275 aab32f28c4571fa291067919a015563d 308 Gene3D G3DSA:3.30.360.10 121 308 1.6E-51 T 01-11-2018 MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 SUPERFAMILY SSF46689 3 70 3.64E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 Gene3D G3DSA:1.10.357.10 1 204 2.9E-38 T 01-11-2018 MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.8E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.8E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 SUPERFAMILY SSF48498 77 160 4.52E-8 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_24170 728f938f63876fda178eb0642bb19403 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 4.9E-16 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_25125 ff751a507cc3ff705cd07b66136f05ef 192 SUPERFAMILY SSF53335 5 168 5.92E-26 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_25125 ff751a507cc3ff705cd07b66136f05ef 192 Gene3D G3DSA:3.40.50.150 14 186 5.0E-19 T 01-11-2018 MLA2C4_25125 ff751a507cc3ff705cd07b66136f05ef 192 Pfam PF00398 Ribosomal RNA adenine dimethylase 25 147 4.8E-11 T 01-11-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MLA2C4_20240 30bcfd18345fe08a11d7fdc2386ce10f 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 3.6E-41 T 01-11-2018 IPR013527 YicC-like, N-terminal MLA2C4_20240 30bcfd18345fe08a11d7fdc2386ce10f 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 8.0E-88 T 01-11-2018 IPR005229 Conserved hypothetical protein CHP00255 MLA2C4_20240 30bcfd18345fe08a11d7fdc2386ce10f 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 6.4E-38 T 01-11-2018 IPR013551 Domain of unknown function DUF1732 MLA2C4_04765 95ff26e86c8e1796353652d21c76a7a2 492 Gene3D G3DSA:3.30.750.24 387 477 1.7E-11 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_04765 95ff26e86c8e1796353652d21c76a7a2 492 SUPERFAMILY SSF52091 397 478 3.14E-12 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_04765 95ff26e86c8e1796353652d21c76a7a2 492 Pfam PF01740 STAS domain 402 490 5.4E-8 T 01-11-2018 IPR002645 STAS domain MLA2C4_04765 95ff26e86c8e1796353652d21c76a7a2 492 Pfam PF00916 Sulfate permease family 139 359 1.4E-38 T 01-11-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MLA2C4_04765 95ff26e86c8e1796353652d21c76a7a2 492 Pfam PF00916 Sulfate permease family 8 134 1.9E-25 T 01-11-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MLA2C4_27885 e325f2f2af15a96353af58f43cc5feb7 145 SUPERFAMILY SSF54593 1 120 1.29E-22 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_27885 e325f2f2af15a96353af58f43cc5feb7 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 1.0E-15 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_27885 e325f2f2af15a96353af58f43cc5feb7 145 Gene3D G3DSA:3.10.180.10 1 123 4.1E-48 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 Gene3D G3DSA:3.20.20.100 1 279 1.2E-125 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 Pfam PF00248 Aldo/keto reductase family 29 265 6.1E-48 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 1.2E-51 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 1.2E-51 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.2E-51 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.2E-51 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 1.2E-51 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 SUPERFAMILY SSF51430 5 274 1.57E-94 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PIRSF PIRSF000097 119 276 1.5E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_26360 4ed30e9239c2196a6090fbb77680d3cc 279 PIRSF PIRSF000097 1 124 4.7E-42 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_10960 1166a8c3e5a8a74c6a7ab2e3d1c11f32 111 Gene3D G3DSA:2.40.50.140 1 110 3.2E-40 T 01-11-2018 MLA2C4_10960 1166a8c3e5a8a74c6a7ab2e3d1c11f32 111 SUPERFAMILY SSF50249 1 109 4.11E-39 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_10960 1166a8c3e5a8a74c6a7ab2e3d1c11f32 111 PIRSF PIRSF002070 1 111 4.2E-34 T 01-11-2018 MLA2C4_10960 1166a8c3e5a8a74c6a7ab2e3d1c11f32 111 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 30.447 T 01-11-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_10960 1166a8c3e5a8a74c6a7ab2e3d1c11f32 111 Pfam PF00436 Single-strand binding protein family 2 103 1.2E-32 T 01-11-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MLA2C4_10960 1166a8c3e5a8a74c6a7ab2e3d1c11f32 111 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 106 9.1E-31 T 01-11-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_01840 f76fa621a11e7279d957998e3b8b4e71 397 PIRSF PIRSF012509 1 397 9.1E-147 T 01-11-2018 IPR011426 CamS sex pheromone cAM373 MLA2C4_01840 f76fa621a11e7279d957998e3b8b4e71 397 Gene3D G3DSA:3.10.570.10 53 397 3.8E-120 T 01-11-2018 MLA2C4_01840 f76fa621a11e7279d957998e3b8b4e71 397 Pfam PF07537 CamS sex pheromone cAM373 precursor 57 389 4.9E-113 T 01-11-2018 IPR011426 CamS sex pheromone cAM373 MLA2C4_15730 ee3d75a02b41a7e68b0a5510ac582d41 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 395 1.5E-47 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_15730 ee3d75a02b41a7e68b0a5510ac582d41 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 79 1.5E-18 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 Gene3D G3DSA:1.20.1250.20 209 398 1.6E-33 T 01-11-2018 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 SUPERFAMILY SSF103473 5 392 8.72E-73 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 Gene3D G3DSA:1.20.1250.20 2 208 6.7E-43 T 01-11-2018 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 Pfam PF07690 Major Facilitator Superfamily 12 295 2.3E-39 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 PRINTS PR01035 Tetracycline resistance protein signature 340 363 2.2E-7 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 PRINTS PR01035 Tetracycline resistance protein signature 106 127 2.2E-7 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 PRINTS PR01035 Tetracycline resistance protein signature 279 300 2.2E-7 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 PRINTS PR01035 Tetracycline resistance protein signature 17 33 2.2E-7 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 PRINTS PR01035 Tetracycline resistance protein signature 136 158 2.2E-7 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_09490 7caa6842300937dc45645ee9186ae228 404 PRINTS PR01035 Tetracycline resistance protein signature 79 103 2.2E-7 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 PRINTS PR01035 Tetracycline resistance protein signature 18 34 1.6E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 PRINTS PR01035 Tetracycline resistance protein signature 167 187 1.6E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 PRINTS PR01035 Tetracycline resistance protein signature 282 303 1.6E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 PRINTS PR01035 Tetracycline resistance protein signature 339 362 1.6E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 PRINTS PR01035 Tetracycline resistance protein signature 139 161 1.6E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 Gene3D G3DSA:1.20.1250.20 3 397 3.0E-65 T 01-11-2018 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 SUPERFAMILY SSF103473 8 400 3.92E-65 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 Pfam PF07690 Major Facilitator Superfamily 283 405 6.1E-16 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 Pfam PF07690 Major Facilitator Superfamily 17 275 3.5E-39 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_10115 c7831f538b4e74e7f6be1f032c3e618a 409 ProSitePatterns PS00217 Sugar transport proteins signature 2. 315 340 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_17895 d2e5292372d236228a41bd2fadd96ac2 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17895 d2e5292372d236228a41bd2fadd96ac2 253 Pfam PF00005 ABC transporter 21 162 9.0E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17895 d2e5292372d236228a41bd2fadd96ac2 253 SUPERFAMILY SSF52540 5 223 3.44E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17895 d2e5292372d236228a41bd2fadd96ac2 253 Gene3D G3DSA:3.40.50.300 1 236 1.6E-64 T 01-11-2018 MLA2C4_17895 d2e5292372d236228a41bd2fadd96ac2 253 SMART SM00382 30 219 1.3E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02385 4e1e53fbf77bbb82bb8779e41cbef5f2 97 Pfam PF14150 YesK-like protein 10 90 2.2E-32 T 01-11-2018 IPR025434 YesK-like protein MLA2C4_02895 1ad4086f8e6ebe06b650c2d960504dcc 153 SUPERFAMILY SSF55811 4 140 3.93E-29 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_02895 1ad4086f8e6ebe06b650c2d960504dcc 153 Pfam PF00293 NUDIX domain 8 112 1.2E-20 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_02895 1ad4086f8e6ebe06b650c2d960504dcc 153 Gene3D G3DSA:3.90.79.10 3 136 1.7E-29 T 01-11-2018 MLA2C4_02895 1ad4086f8e6ebe06b650c2d960504dcc 153 PRINTS PR00502 NUDIX hydrolase family signature 35 49 2.2E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_02895 1ad4086f8e6ebe06b650c2d960504dcc 153 PRINTS PR00502 NUDIX hydrolase family signature 49 64 2.2E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_02895 1ad4086f8e6ebe06b650c2d960504dcc 153 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 SUPERFAMILY SSF51306 27 182 4.45E-51 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 01-11-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 7.0E-20 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 7.0E-20 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 7.0E-20 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 Gene3D G3DSA:2.10.109.10 59 182 3.5E-44 T 01-11-2018 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 01-11-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 2.7E-51 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 01-11-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MLA2C4_16195 877f91a7506724d26ef1bbde6241bf3b 183 Pfam PF00717 Peptidase S24-like 36 103 8.2E-18 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_05205 decd8a2eaff710c16fc08f99175dc4eb 116 Gene3D G3DSA:2.30.30.40 50 111 2.1E-6 T 01-11-2018 MLA2C4_05205 decd8a2eaff710c16fc08f99175dc4eb 116 Pfam PF08239 Bacterial SH3 domain 51 111 2.5E-6 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_04000 18e2afda71b48e80e197693a926cf402 193 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 191 33.116 T 01-11-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MLA2C4_04000 18e2afda71b48e80e197693a926cf402 193 Pfam PF02669 K+-transporting ATPase, c chain 10 189 3.1E-71 T 01-11-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MLA2C4_04000 18e2afda71b48e80e197693a926cf402 193 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 8 191 8.7E-59 T 01-11-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MLA2C4_04000 18e2afda71b48e80e197693a926cf402 193 PIRSF PIRSF001296 4 193 1.9E-77 T 01-11-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MLA2C4_26420 7a89a39a4e47c463bc8b6c3b2a8e7db1 79 Pfam PF13135 Protein of unknown function (DUF3947) 2 79 2.0E-28 T 01-11-2018 IPR025039 Protein of unknown function DUF3947 MLA2C4_18785 66c9f6eda08d24ec93e3ab8054381b22 237 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 100 201 2.5E-12 T 01-11-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_18785 66c9f6eda08d24ec93e3ab8054381b22 237 Gene3D G3DSA:3.90.470.20 100 202 1.3E-47 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_18785 66c9f6eda08d24ec93e3ab8054381b22 237 SUPERFAMILY SSF56214 26 92 5.02E-11 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_18785 66c9f6eda08d24ec93e3ab8054381b22 237 Gene3D G3DSA:3.90.470.20 19 204 1.3E-47 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_18785 66c9f6eda08d24ec93e3ab8054381b22 237 SUPERFAMILY SSF56214 100 213 1.74E-19 T 01-11-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Pfam PF00704 Glycosyl hydrolases family 18 187 410 7.6E-24 T 01-11-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Pfam PF01476 LysM domain 54 97 2.4E-10 T 01-11-2018 IPR018392 LysM domain MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Pfam PF01476 LysM domain 5 47 1.5E-9 T 01-11-2018 IPR018392 LysM domain MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 SUPERFAMILY SSF51445 130 427 3.86E-46 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 SMART SM00257 53 97 9.1E-11 T 01-11-2018 IPR018392 LysM domain MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 SMART SM00257 4 48 1.0E-8 T 01-11-2018 IPR018392 LysM domain MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Gene3D G3DSA:3.10.350.10 2 51 1.1E-11 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 SUPERFAMILY SSF54106 54 97 2.35E-10 T 01-11-2018 MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Gene3D G3DSA:3.10.50.10 324 383 3.5E-120 T 01-11-2018 IPR029070 Chitinase insertion domain superfamily MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 SUPERFAMILY SSF54106 4 48 6.02E-8 T 01-11-2018 MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 SMART SM00636 104 412 1.2E-28 T 01-11-2018 IPR011583 Chitinase II GO:0008061 MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Gene3D G3DSA:3.10.350.10 52 104 1.0E-14 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_18730 8db77f6a0efbd27ed3e166cf52c36439 430 Gene3D G3DSA:3.20.20.80 132 419 3.5E-120 T 01-11-2018 MLA2C4_00790 655b431335a7bd76b1d6c7d3440f8898 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.9E-29 T 01-11-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MLA2C4_00790 655b431335a7bd76b1d6c7d3440f8898 72 Gene3D G3DSA:2.40.50.140 1 72 6.1E-38 T 01-11-2018 MLA2C4_00790 655b431335a7bd76b1d6c7d3440f8898 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.88 T 01-11-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MLA2C4_00790 655b431335a7bd76b1d6c7d3440f8898 72 SMART SM00316 4 72 6.8E-6 T 01-11-2018 IPR022967 RNA-binding domain, S1 MLA2C4_00790 655b431335a7bd76b1d6c7d3440f8898 72 SUPERFAMILY SSF50249 1 71 7.89E-29 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_00790 655b431335a7bd76b1d6c7d3440f8898 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 4.4E-39 T 01-11-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MLA2C4_04050 8f0129f8183cb4bd9662fdfff0fc21e5 433 Pfam PF00860 Permease family 14 394 1.2E-61 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_04050 8f0129f8183cb4bd9662fdfff0fc21e5 433 PIRSF PIRSF005353 1 433 8.2E-159 T 01-11-2018 IPR026033 Purine permease PbuG-like MLA2C4_22310 52e2bab829806c0b401d416552a41239 218 PIRSF PIRSF003107 1 218 3.6E-62 T 01-11-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MLA2C4_22310 52e2bab829806c0b401d416552a41239 218 Pfam PF01895 PhoU domain 18 105 7.0E-22 T 01-11-2018 IPR026022 PhoU domain MLA2C4_22310 52e2bab829806c0b401d416552a41239 218 Pfam PF01895 PhoU domain 120 204 7.6E-19 T 01-11-2018 IPR026022 PhoU domain MLA2C4_22310 52e2bab829806c0b401d416552a41239 218 Gene3D G3DSA:1.20.58.220 2 218 2.3E-71 T 01-11-2018 IPR038078 PhoU-like domain superfamily MLA2C4_22310 52e2bab829806c0b401d416552a41239 218 SUPERFAMILY SSF109755 3 215 1.78E-64 T 01-11-2018 MLA2C4_22310 52e2bab829806c0b401d416552a41239 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 213 1.7E-70 T 01-11-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 Pfam PF13840 ACT domain 334 396 1.7E-11 T 01-11-2018 IPR027795 CASTOR, ACT domain MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 SUPERFAMILY SSF55021 250 323 3.15E-13 T 01-11-2018 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 Gene3D G3DSA:3.30.70.260 255 398 5.4E-46 T 01-11-2018 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 399 9.6E-144 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 Gene3D G3DSA:3.40.1160.10 1 254 2.2E-89 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 399 7.8E-119 T 01-11-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 01-11-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 Pfam PF00696 Amino acid kinase family 3 226 9.0E-52 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 PIRSF PIRSF000726 53 405 7.2E-129 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 PIRSF PIRSF000726 1 61 3.6E-19 T 01-11-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 SUPERFAMILY SSF55021 325 400 2.32E-20 T 01-11-2018 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 Gene3D G3DSA:3.30.70.260 260 335 5.4E-46 T 01-11-2018 MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 SUPERFAMILY SSF53633 3 243 9.82E-73 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_09200 7938578e00ca5e5a660ed30904e3a266 409 Pfam PF01842 ACT domain 272 324 8.2E-8 T 01-11-2018 IPR002912 ACT domain MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 6.9E-135 T 01-11-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 01-11-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 Gene3D G3DSA:3.40.50.150 15 234 3.7E-66 T 01-11-2018 MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 SUPERFAMILY SSF53335 3 229 7.91E-50 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.569 T 01-11-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 01-11-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.5E-102 T 01-11-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MLA2C4_07960 47b8db68e51f0eafaed2aeeed2e5387d 237 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 3.3E-81 T 01-11-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MLA2C4_09440 81abeeb68a99c14dc5198c7d270ce255 299 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 01-11-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MLA2C4_09440 81abeeb68a99c14dc5198c7d270ce255 299 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 287 1.0E-103 T 01-11-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 MLA2C4_09440 81abeeb68a99c14dc5198c7d270ce255 299 Gene3D G3DSA:3.30.470.10 1 126 9.5E-47 T 01-11-2018 MLA2C4_09440 81abeeb68a99c14dc5198c7d270ce255 299 Gene3D G3DSA:3.20.10.10 127 288 7.0E-59 T 01-11-2018 MLA2C4_09440 81abeeb68a99c14dc5198c7d270ce255 299 Pfam PF01063 Amino-transferase class IV 32 258 8.0E-59 T 01-11-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MLA2C4_09440 81abeeb68a99c14dc5198c7d270ce255 299 SUPERFAMILY SSF56752 3 286 1.83E-93 T 01-11-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MLA2C4_26125 c5e1a187ca6c9d980ba83b7393b207ba 437 Gene3D G3DSA:1.20.1740.10 3 437 7.1E-94 T 01-11-2018 MLA2C4_26125 c5e1a187ca6c9d980ba83b7393b207ba 437 PIRSF PIRSF006060 1 436 7.1E-81 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_26125 c5e1a187ca6c9d980ba83b7393b207ba 437 Pfam PF13520 Amino acid permease 11 406 6.4E-61 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Gene3D G3DSA:3.40.50.11180 36 326 3.8E-64 T 01-11-2018 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Pfam PF03461 TRCF domain 1025 1117 2.6E-26 T 01-11-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Pfam PF00270 DEAD/DEAH box helicase 625 784 9.7E-18 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SUPERFAMILY SSF52540 802 1008 8.11E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Pfam PF00271 Helicase conserved C-terminal domain 828 929 2.0E-17 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Gene3D G3DSA:3.40.50.300 498 1008 1.2E-246 T 01-11-2018 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Gene3D G3DSA:3.90.1150.50 1020 1175 4.1E-40 T 01-11-2018 IPR037235 TRCF-like, C-terminal domain MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1098 0.0 T 01-11-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SUPERFAMILY SSF52540 377 490 4.19E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SUPERFAMILY SSF52540 13 367 8.21E-92 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 27 1118 28.913 T 01-11-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SUPERFAMILY SSF141259 490 568 1.7E-26 T 01-11-2018 IPR036101 CarD-like/TRCF domain superfamily MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Gene3D G3DSA:3.30.2060.10 140 225 3.8E-64 T 01-11-2018 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Pfam PF02559 CarD-like/TRCF domain 500 595 7.0E-32 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SUPERFAMILY SSF52540 543 803 1.32E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SMART SM00490 846 930 2.7E-19 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Gene3D G3DSA:2.30.30.840 503 561 1.2E-246 T 01-11-2018 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SMART SM00487 620 810 6.6E-36 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SMART SM01058 499 596 5.8E-50 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 Gene3D G3DSA:3.40.50.300 562 801 1.2E-246 T 01-11-2018 MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SUPERFAMILY SSF143517 1015 1168 6.67E-35 T 01-11-2018 IPR037235 TRCF-like, C-terminal domain MLA2C4_00300 9d5b9fef1129bea91e420570ceb46801 1176 SMART SM00982 1024 1124 1.1E-38 T 01-11-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 Pfam PF07690 Major Facilitator Superfamily 27 417 3.0E-44 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 1.1E-5 T 01-11-2018 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 311 335 1.1E-5 T 01-11-2018 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.1E-5 T 01-11-2018 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 Gene3D G3DSA:1.20.1250.20 270 483 4.8E-20 T 01-11-2018 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 Gene3D G3DSA:1.20.1720.10 23 236 2.4E-34 T 01-11-2018 MLA2C4_05030 16c6a512558d90713718db90753e3531 491 SUPERFAMILY SSF103473 16 480 1.27E-60 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_05030 16c6a512558d90713718db90753e3531 491 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 440 2.1E-100 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_15445 a004f655d669671a1b6737a3c8917d37 170 Pfam PF04167 Protein of unknown function (DUF402) 65 129 3.5E-14 T 01-11-2018 IPR007295 Domain of unknown function DUF402 MLA2C4_15445 a004f655d669671a1b6737a3c8917d37 170 Gene3D G3DSA:2.40.380.10 7 167 1.5E-7 T 01-11-2018 IPR035930 FomD-like superfamily MLA2C4_15445 a004f655d669671a1b6737a3c8917d37 170 SUPERFAMILY SSF159234 22 153 1.23E-27 T 01-11-2018 IPR035930 FomD-like superfamily MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 Gene3D G3DSA:3.40.630.30 131 282 4.7E-65 T 01-11-2018 MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 Gene3D G3DSA:3.40.630.30 1 130 1.2E-56 T 01-11-2018 MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 Pfam PF13527 Acetyltransferase (GNAT) domain 4 127 1.9E-36 T 01-11-2018 MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 SUPERFAMILY SSF55729 1 280 6.79E-73 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 SUPERFAMILY SSF55718 281 386 5.89E-26 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 Pfam PF13530 Sterol carrier protein domain 175 382 3.4E-52 T 01-11-2018 IPR025559 Enhanced intracellular survival protein domain MLA2C4_15545 1c6418fa5a517958d19358e18dc7e8ac 386 Gene3D G3DSA:3.30.1050.10 283 376 8.8E-26 T 01-11-2018 IPR036527 SCP2 sterol-binding domain superfamily MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 SUPERFAMILY SSF52540 45 680 2.8E-129 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Gene3D G3DSA:3.40.50.300 319 674 3.5E-72 T 01-11-2018 MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 51 154 5.0E-24 T 01-11-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 155 309 2.4E-35 T 01-11-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Gene3D G3DSA:3.40.50.300 51 309 1.1E-79 T 01-11-2018 MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Gene3D G3DSA:1.10.486.10 421 578 3.5E-72 T 01-11-2018 MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Gene3D G3DSA:1.10.10.160 150 226 1.1E-79 T 01-11-2018 IPR013986 DExx box DNA helicase domain superfamily MLA2C4_06430 99a519fe71fdf106eec1f08ef0bdd33a 688 Pfam PF13361 UvrD-like helicase C-terminal domain 314 659 3.9E-43 T 01-11-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 PIRSF PIRSF006294 3 527 2.1E-246 T 01-11-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 SUPERFAMILY SSF53795 213 524 3.2E-137 T 01-11-2018 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 Gene3D G3DSA:2.170.8.10 38 330 3.6E-227 T 01-11-2018 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 Gene3D G3DSA:3.90.228.20 214 513 3.6E-227 T 01-11-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 17 526 8.3E-249 T 01-11-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 SUPERFAMILY SSF68923 8 212 2.96E-81 T 01-11-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 01-11-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 20 481 4.1E-229 T 01-11-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 Gene3D G3DSA:3.40.449.10 28 213 3.6E-227 T 01-11-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MLA2C4_24815 083c9ba63b0e1bfa6375fa943346cc6e 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 528 56.242 T 01-11-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MLA2C4_22055 ec35eee4344c6ee47415e748c64e73e9 85 Pfam PF13126 Protein of unknown function (DUF3975) 1 80 9.4E-47 T 01-11-2018 IPR025015 Protein of unknown function DUF3975 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 SUPERFAMILY SSF47729 1 90 1.91E-34 T 01-11-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 Gene3D G3DSA:4.10.520.10 1 90 6.7E-40 T 01-11-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 01-11-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.0E-21 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.0E-21 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.0E-21 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.5E-36 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_12235 e451f3e12d629bfd6d18cc618421f556 90 SMART SM00411 1 90 1.8E-48 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 PIRSF PIRSF002401 1 375 5.4E-142 T 01-11-2018 IPR035101 GTP-binding protein, Obg-type MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.2E-22 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 6.2E-25 T 01-11-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Pfam PF01018 GTP1/OBG 3 157 1.2E-59 T 01-11-2018 IPR006169 GTP1/OBG domain MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 SUPERFAMILY SSF82051 1 157 2.22E-54 T 01-11-2018 IPR036726 GTP1/OBG domain superfamily MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Gene3D G3DSA:2.70.210.12 1 157 9.5E-60 T 01-11-2018 IPR036726 GTP1/OBG domain superfamily MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Gene3D G3DSA:3.40.50.300 158 340 2.9E-61 T 01-11-2018 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 01-11-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.4E-34 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.4E-34 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.4E-34 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.4E-34 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 2.2E-26 T 01-11-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Gene3D G3DSA:2.40.240.60 357 428 3.1E-18 T 01-11-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 6.1E-14 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 SUPERFAMILY SSF52540 160 332 7.19E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 1.7E-142 T 01-11-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 SUPERFAMILY SSF102741 357 428 1.83E-23 T 01-11-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily MLA2C4_23150 b34bf6244b592c5d451fe41bb34c0124 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 47.842 T 01-11-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 1.2E-109 T 01-11-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 SUPERFAMILY SSF54814 181 297 1.23E-43 T 01-11-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 Gene3D G3DSA:3.30.300.20 186 300 6.8E-44 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_22460 94979fe045970635affed0cafb29667f 301 Pfam PF07650 KH domain 208 285 2.1E-21 T 01-11-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 4.0E-31 T 01-11-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 SUPERFAMILY SSF52540 11 206 1.08E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22460 94979fe045970635affed0cafb29667f 301 Gene3D G3DSA:3.40.50.300 4 185 1.8E-51 T 01-11-2018 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 Hamap MF_00367 GTPase Era [era]. 6 296 39.488 T 01-11-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 3.0E-5 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 3.0E-5 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_22460 94979fe045970635affed0cafb29667f 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 7.0E-26 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 Pfam PF00013 KH domain 213 267 3.4E-6 T 01-11-2018 IPR004088 K Homology domain, type 1 GO:0003723 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 Hamap MF_00335 Ribonuclease Y [rny]. 5 520 25.868 T 01-11-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 SUPERFAMILY SSF109604 316 467 1.59E-30 T 01-11-2018 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 Pfam PF01966 HD domain 337 428 4.1E-19 T 01-11-2018 IPR006674 HD domain MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 SUPERFAMILY SSF54791 208 304 3.42E-16 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 Pfam PF12072 Domain of unknown function (DUF3552) 6 205 4.6E-77 T 01-11-2018 IPR022711 Ribonuclease Y, N-terminal MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 SMART SM00471 332 438 4.7E-14 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 SMART SM00322 208 275 1.1E-6 T 01-11-2018 IPR004087 K Homology domain GO:0003676 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 520 3.1E-246 T 01-11-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 TIGRFAM TIGR00277 HDIG: HDIG domain 332 409 3.1E-26 T 01-11-2018 IPR006675 HDIG domain MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 Gene3D G3DSA:1.10.3210.10 318 472 2.6E-19 T 01-11-2018 MLA2C4_19755 23c572e6181b3bbb2944fc3b405ba00d 520 Gene3D G3DSA:3.30.1370.10 207 303 1.1E-8 T 01-11-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 Gene3D G3DSA:3.40.50.1820 309 412 1.2E-6 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 Gene3D G3DSA:2.60.120.260 425 596 1.0E-43 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 SMART SM00939 381 595 6.3E-44 T 01-11-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 SUPERFAMILY SSF49785 445 597 9.35E-38 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 Gene3D G3DSA:3.40.50.1820 75 291 5.9E-66 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 90 369 5.0E-74 T 01-11-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 76 86 8.1E-6 T 01-11-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 110 126 8.1E-6 T 01-11-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 94 103 8.1E-6 T 01-11-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 SUPERFAMILY SSF53474 57 416 7.92E-83 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_15130 390d2f82e881d965c41ecf56b00d6c30 598 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 393 592 2.8E-31 T 01-11-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 MLA2C4_15105 aec027d356e62dcc4e175aa2e87f15ac 143 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 108 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_15105 aec027d356e62dcc4e175aa2e87f15ac 143 SUPERFAMILY SSF53927 9 140 1.07E-24 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_15105 aec027d356e62dcc4e175aa2e87f15ac 143 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 11 117 1.0E-7 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MLA2C4_15105 aec027d356e62dcc4e175aa2e87f15ac 143 Gene3D G3DSA:3.40.140.10 10 143 4.3E-29 T 01-11-2018 MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 SMART SM00642 11 411 2.5E-153 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 Pfam PF00128 Alpha amylase, catalytic domain 26 369 8.6E-125 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 SUPERFAMILY SSF51445 3 469 2.32E-153 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 SUPERFAMILY SSF51011 472 550 1.92E-18 T 01-11-2018 MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 Gene3D G3DSA:2.60.40.1180 473 553 4.1E-23 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 Gene3D G3DSA:3.90.400.10 103 167 2.1E-187 T 01-11-2018 MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 Pfam PF16657 Maltogenic Amylase, C-terminal domain 472 545 4.8E-7 T 01-11-2018 IPR032091 Maltogenic Amylase, C-terminal MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 4 550 4.8E-273 T 01-11-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 MLA2C4_03325 e204f76b9e084603643a55e3ed8a5362 553 Gene3D G3DSA:3.20.20.80 4 464 2.1E-187 T 01-11-2018 MLA2C4_25930 d219f425648c2966a38ff15191031f3d 268 PIRSF PIRSF002854 1 267 2.3E-99 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_25930 d219f425648c2966a38ff15191031f3d 268 SUPERFAMILY SSF53850 27 266 2.94E-80 T 01-11-2018 MLA2C4_25930 d219f425648c2966a38ff15191031f3d 268 Pfam PF03180 NLPA lipoprotein 28 266 8.8E-89 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_25930 d219f425648c2966a38ff15191031f3d 268 Gene3D G3DSA:3.40.190.10 109 217 3.1E-97 T 01-11-2018 MLA2C4_25930 d219f425648c2966a38ff15191031f3d 268 Gene3D G3DSA:3.40.190.10 30 263 3.1E-97 T 01-11-2018 MLA2C4_19305 083336cffa22e0c8dace2eee1a30f591 399 Gene3D G3DSA:3.40.50.2000 227 388 7.7E-35 T 01-11-2018 MLA2C4_19305 083336cffa22e0c8dace2eee1a30f591 399 Pfam PF00534 Glycosyl transferases group 1 229 382 5.7E-28 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_19305 083336cffa22e0c8dace2eee1a30f591 399 SUPERFAMILY SSF53756 1 398 5.89E-53 T 01-11-2018 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 418 1.6E-18 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 Gene3D G3DSA:3.30.565.10 274 423 1.3E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 SUPERFAMILY SSF55874 263 419 2.36E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 SMART SM00388 209 273 3.8E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 Gene3D G3DSA:1.10.287.130 212 270 2.1E-17 T 01-11-2018 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 270 8.9E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 SMART SM00387 314 421 4.8E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 SUPERFAMILY SSF47384 202 271 6.28E-13 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 1.1E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 1.1E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_20950 1f16de278a11444ba0ac858dcc2f4978 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 1.1E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Pfam PF03717 Penicillin-binding Protein dimerisation domain 144 311 2.0E-33 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 SUPERFAMILY SSF56601 326 654 2.82E-77 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 SUPERFAMILY SSF54427 27 135 1.2E-31 T 01-11-2018 IPR032710 NTF2-like domain superfamily MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Gene3D G3DSA:3.90.1310.10 146 321 4.3E-51 T 01-11-2018 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Gene3D G3DSA:3.40.710.10 325 655 3.1E-81 T 01-11-2018 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Gene3D G3DSA:3.30.1390.30 165 236 4.3E-51 T 01-11-2018 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Gene3D G3DSA:3.10.450.100 23 132 9.2E-35 T 01-11-2018 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 24 136 2.5E-30 T 01-11-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 Pfam PF00905 Penicillin binding protein transpeptidase domain 345 652 1.5E-62 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_13330 798b8a085bd5f6a2059afa0c8c45ac31 655 SUPERFAMILY SSF56519 139 325 8.37E-39 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 SUPERFAMILY SSF50156 128 213 3.02E-16 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 Gene3D G3DSA:2.30.42.10 123 217 1.2E-26 T 01-11-2018 MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 SMART SM00228 120 187 0.0012 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 Pfam PF13180 PDZ domain 128 194 3.9E-15 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 SUPERFAMILY SSF54211 229 334 2.28E-22 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 Gene3D G3DSA:3.30.230.10 218 341 3.1E-19 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_20515 eccef5a099eebc3e34c8eb9696337612 341 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 233 331 5.0E-11 T 01-11-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MLA2C4_13645 c454baf4cc5ab572fcf85dfad9de231a 320 Pfam PF08279 HTH domain 8 60 1.1E-13 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_13645 c454baf4cc5ab572fcf85dfad9de231a 320 SUPERFAMILY SSF46785 4 60 5.45E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_13645 c454baf4cc5ab572fcf85dfad9de231a 320 Gene3D G3DSA:1.10.10.10 3 63 1.1E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_13645 c454baf4cc5ab572fcf85dfad9de231a 320 Pfam PF13280 WYL domain 139 314 9.8E-29 T 01-11-2018 IPR026881 WYL domain MLA2C4_22245 c789fdd169adbc2ef92498c956e209c8 610 Pfam PF02574 Homocysteine S-methyltransferase 12 280 2.2E-50 T 01-11-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MLA2C4_22245 c789fdd169adbc2ef92498c956e209c8 610 Gene3D G3DSA:3.20.20.330 1 292 1.7E-82 T 01-11-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MLA2C4_22245 c789fdd169adbc2ef92498c956e209c8 610 Gene3D G3DSA:3.20.20.220 309 598 2.9E-56 T 01-11-2018 MLA2C4_22245 c789fdd169adbc2ef92498c956e209c8 610 SUPERFAMILY SSF51730 316 600 5.49E-71 T 01-11-2018 IPR029041 FAD-linked oxidoreductase-like MLA2C4_22245 c789fdd169adbc2ef92498c956e209c8 610 SUPERFAMILY SSF82282 3 360 4.84E-93 T 01-11-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MLA2C4_22245 c789fdd169adbc2ef92498c956e209c8 610 Pfam PF02219 Methylenetetrahydrofolate reductase 316 575 7.4E-31 T 01-11-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MLA2C4_27915 9c318cb2e4b3c25224267bf7ffd8d131 323 Gene3D G3DSA:3.40.50.10950 19 319 6.3E-134 T 01-11-2018 MLA2C4_27915 9c318cb2e4b3c25224267bf7ffd8d131 323 SUPERFAMILY SSF53659 5 322 4.93E-93 T 01-11-2018 MLA2C4_27915 9c318cb2e4b3c25224267bf7ffd8d131 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 8.0E-127 T 01-11-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_27915 9c318cb2e4b3c25224267bf7ffd8d131 323 PIRSF PIRSF000428 1 323 1.7E-110 T 01-11-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_27915 9c318cb2e4b3c25224267bf7ffd8d131 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 319 1.4E-128 T 01-11-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MLA2C4_27915 9c318cb2e4b3c25224267bf7ffd8d131 323 Gene3D G3DSA:3.40.50.10750 142 295 6.3E-134 T 01-11-2018 MLA2C4_22260 eabba62e86cf5834f5f8509eb2057890 170 Gene3D G3DSA:3.40.50.850 5 168 7.7E-36 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_22260 eabba62e86cf5834f5f8509eb2057890 170 SUPERFAMILY SSF52499 7 166 6.15E-38 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_22260 eabba62e86cf5834f5f8509eb2057890 170 Pfam PF00857 Isochorismatase family 7 143 3.8E-30 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_10265 5aeba7fc762120717e284697908a7a85 333 Pfam PF00296 Luciferase-like monooxygenase 3 301 2.1E-32 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MLA2C4_10265 5aeba7fc762120717e284697908a7a85 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 330 2.2E-125 T 01-11-2018 IPR019949 Luciferase family oxidoreductase, group 1 MLA2C4_10265 5aeba7fc762120717e284697908a7a85 333 SUPERFAMILY SSF51679 2 329 5.3E-72 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_10265 5aeba7fc762120717e284697908a7a85 333 Gene3D G3DSA:3.20.20.30 1 333 3.4E-98 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 Gene3D G3DSA:1.10.286.20 193 239 5.1E-42 T 01-11-2018 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 01-11-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 Gene3D G3DSA:1.10.8.10 1 55 9.7E-29 T 01-11-2018 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 01-11-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 SUPERFAMILY SSF54713 55 144 6.8E-22 T 01-11-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 SUPERFAMILY SSF54713 151 293 2.62E-52 T 01-11-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 SUPERFAMILY SSF46934 1 55 1.22E-21 T 01-11-2018 IPR009060 UBA-like superfamily GO:0005515 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 Gene3D G3DSA:3.30.479.20 56 146 1.7E-23 T 01-11-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 Gene3D G3DSA:3.30.479.20 155 273 5.1E-42 T 01-11-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 2.3E-118 T 01-11-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 83.252 T 01-11-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_20000 154ad5f19464815cb36acb8edd2d7354 295 Pfam PF00889 Elongation factor TS 70 274 6.1E-75 T 01-11-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 MLA2C4_22315 fbefa0390da64292d45fcd2bcf76a076 271 SUPERFAMILY SSF52540 20 258 3.87E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22315 fbefa0390da64292d45fcd2bcf76a076 271 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 271 3.4E-126 T 01-11-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MLA2C4_22315 fbefa0390da64292d45fcd2bcf76a076 271 Gene3D G3DSA:3.40.50.300 22 267 7.4E-63 T 01-11-2018 MLA2C4_22315 fbefa0390da64292d45fcd2bcf76a076 271 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_22315 fbefa0390da64292d45fcd2bcf76a076 271 SMART SM00382 49 258 7.2E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_22315 fbefa0390da64292d45fcd2bcf76a076 271 Pfam PF00005 ABC transporter 40 196 3.2E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_07030 b555847e4347cc442bef413156131610 585 Gene3D G3DSA:1.10.3720.10 312 576 1.0E-32 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_07030 b555847e4347cc442bef413156131610 585 Gene3D G3DSA:1.10.3720.10 28 292 5.9E-56 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_07030 b555847e4347cc442bef413156131610 585 SUPERFAMILY SSF161098 23 289 3.83E-50 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_07030 b555847e4347cc442bef413156131610 585 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 397 574 4.9E-10 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_07030 b555847e4347cc442bef413156131610 585 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 287 5.8E-11 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_07030 b555847e4347cc442bef413156131610 585 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 25 585 6.5E-251 T 01-11-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative MLA2C4_07030 b555847e4347cc442bef413156131610 585 SUPERFAMILY SSF161098 312 570 2.8E-34 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_17865 33c252d19dce6d5bc32fb044c55acb67 196 SUPERFAMILY SSF48498 77 191 1.78E-19 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_17865 33c252d19dce6d5bc32fb044c55acb67 196 SUPERFAMILY SSF46689 6 81 6.16E-14 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_17865 33c252d19dce6d5bc32fb044c55acb67 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 5.9E-11 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17865 33c252d19dce6d5bc32fb044c55acb67 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.1E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17865 33c252d19dce6d5bc32fb044c55acb67 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.1E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17865 33c252d19dce6d5bc32fb044c55acb67 196 Gene3D G3DSA:1.10.357.10 1 195 1.2E-48 T 01-11-2018 MLA2C4_03690 0fb6d4dbb6beb323dfc340447a7aefa2 200 SUPERFAMILY SSF81452 18 197 2.35E-53 T 01-11-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03690 0fb6d4dbb6beb323dfc340447a7aefa2 200 Gene3D G3DSA:1.20.120.80 14 199 1.3E-53 T 01-11-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03690 0fb6d4dbb6beb323dfc340447a7aefa2 200 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 11 199 3.5E-104 T 01-11-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 MLA2C4_03690 0fb6d4dbb6beb323dfc340447a7aefa2 200 Pfam PF00510 Cytochrome c oxidase subunit III 22 197 1.8E-14 T 01-11-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 Gene3D G3DSA:3.30.470.20 185 314 1.7E-45 T 01-11-2018 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 SUPERFAMILY SSF52009 768 866 5.62E-27 T 01-11-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 SUPERFAMILY SSF56059 1 342 2.12E-94 T 01-11-2018 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 315 4.0E-94 T 01-11-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 Gene3D G3DSA:3.30.1490.20 1 184 6.0E-70 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 Pfam PF00391 PEP-utilising enzyme, mobile domain 792 863 1.6E-21 T 01-11-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MLA2C4_16305 97af8fc1cd75e22ac2ef70e10dab385e 868 Gene3D G3DSA:3.50.30.10 765 868 9.7E-32 T 01-11-2018 MLA2C4_18915 065b0e41abe56053acd0052760a072e6 269 PIRSF PIRSF006483 1 269 7.9E-88 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_18915 065b0e41abe56053acd0052760a072e6 269 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 4 204 1.4E-61 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_18915 065b0e41abe56053acd0052760a072e6 269 Gene3D G3DSA:3.30.70.120 181 257 6.5E-22 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_18915 065b0e41abe56053acd0052760a072e6 269 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 210 264 3.6E-22 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_23125 9ca9f756aedc94dceafa828453db2569 637 PIRSF PIRSF018968 1 636 5.3E-99 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_23125 9ca9f756aedc94dceafa828453db2569 637 Pfam PF02687 FtsX-like permease family 84 178 6.1E-9 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_00545 9be959f3ea8590d2c3948868a9a81ea5 226 SUPERFAMILY SSF53448 2 221 1.01E-61 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_00545 9be959f3ea8590d2c3948868a9a81ea5 226 Gene3D G3DSA:3.90.550.10 1 225 6.7E-82 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_00545 9be959f3ea8590d2c3948868a9a81ea5 226 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 99 106 - T 01-11-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MLA2C4_00545 9be959f3ea8590d2c3948868a9a81ea5 226 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 221 44.872 T 01-11-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MLA2C4_00545 9be959f3ea8590d2c3948868a9a81ea5 226 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 220 1.3E-75 T 01-11-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MLA2C4_00545 9be959f3ea8590d2c3948868a9a81ea5 226 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 221 1.2E-76 T 01-11-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 SUPERFAMILY SSF50129 1 148 5.33E-38 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 Gene3D G3DSA:3.40.50.720 124 300 1.6E-108 T 01-11-2018 MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 SUPERFAMILY SSF51735 116 296 2.15E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 Pfam PF13602 Zinc-binding dehydrogenase 186 329 1.3E-35 T 01-11-2018 MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 SMART SM00829 11 329 4.3E-27 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 01-11-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 Gene3D G3DSA:3.90.180.10 16 329 1.6E-108 T 01-11-2018 MLA2C4_18200 9918990565c0ae5d35ca3f8e840d36ba 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 90 2.6E-10 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_21875 ccd1842bc2666f20aa03303e0c732747 130 Pfam PF01029 NusB family 4 127 1.8E-40 T 01-11-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MLA2C4_21875 ccd1842bc2666f20aa03303e0c732747 130 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 130 22.881 T 01-11-2018 IPR011605 NusB antitermination factor GO:0006353 MLA2C4_21875 ccd1842bc2666f20aa03303e0c732747 130 Gene3D G3DSA:1.10.940.10 1 130 1.0E-46 T 01-11-2018 IPR035926 NusB-like superfamily MLA2C4_21875 ccd1842bc2666f20aa03303e0c732747 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 129 1.8E-45 T 01-11-2018 IPR011605 NusB antitermination factor GO:0006353 MLA2C4_21875 ccd1842bc2666f20aa03303e0c732747 130 SUPERFAMILY SSF48013 3 126 5.76E-40 T 01-11-2018 IPR035926 NusB-like superfamily MLA2C4_27875 1429014db57257a395f5ae3c7d91ec6d 281 Pfam PF03099 Biotin/lipoate A/B protein ligase family 75 182 4.2E-13 T 01-11-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MLA2C4_27875 1429014db57257a395f5ae3c7d91ec6d 281 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 278 51.655 T 01-11-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 MLA2C4_27875 1429014db57257a395f5ae3c7d91ec6d 281 Gene3D G3DSA:3.30.930.10 5 280 2.8E-79 T 01-11-2018 MLA2C4_27875 1429014db57257a395f5ae3c7d91ec6d 281 SUPERFAMILY SSF55681 7 266 3.31E-69 T 01-11-2018 MLA2C4_23055 5000e2059aac43d4013bf4cf44feb403 314 SUPERFAMILY SSF53807 38 305 1.1E-59 T 01-11-2018 MLA2C4_23055 5000e2059aac43d4013bf4cf44feb403 314 Gene3D G3DSA:3.40.50.1980 35 158 3.5E-30 T 01-11-2018 MLA2C4_23055 5000e2059aac43d4013bf4cf44feb403 314 Gene3D G3DSA:3.40.50.1980 160 314 7.4E-34 T 01-11-2018 MLA2C4_23055 5000e2059aac43d4013bf4cf44feb403 314 Pfam PF01497 Periplasmic binding protein 60 284 4.1E-31 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 195 426 9.2E-80 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 106 120 3.8E-30 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 228 248 3.8E-30 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 186 208 3.8E-30 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 3.8E-30 T 01-11-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 PIRSF PIRSF000185 7 428 8.2E-177 T 01-11-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 SUPERFAMILY SSF51735 195 427 1.69E-79 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 Gene3D G3DSA:3.40.50.720 195 428 1.7E-87 T 01-11-2018 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 51 177 2.1E-54 T 01-11-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 SMART SM00839 197 426 1.2E-97 T 01-11-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 SUPERFAMILY SSF53223 18 197 4.8E-66 T 01-11-2018 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 Gene3D G3DSA:3.40.50.10860 47 182 3.1E-63 T 01-11-2018 MLA2C4_07850 c8578bb412782b8dbba21c0711fbfd18 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 114 127 - T 01-11-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MLA2C4_15695 3358aea8519e276a4293c795b9465d52 167 Gene3D G3DSA:3.40.630.30 2 165 4.6E-29 T 01-11-2018 MLA2C4_15695 3358aea8519e276a4293c795b9465d52 167 SUPERFAMILY SSF55729 9 149 5.32E-27 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15695 3358aea8519e276a4293c795b9465d52 167 Pfam PF13302 Acetyltransferase (GNAT) domain 41 148 2.4E-18 T 01-11-2018 IPR000182 GNAT domain MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 Gene3D G3DSA:1.20.1560.10 1 316 1.2E-90 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 SUPERFAMILY SSF52540 324 571 1.93E-83 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 SMART SM00382 361 547 1.5E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 Gene3D G3DSA:3.40.50.300 331 580 3.1E-83 T 01-11-2018 MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 Pfam PF00005 ABC transporter 352 501 2.1E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 SUPERFAMILY SSF90123 5 318 2.75E-72 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_12520 78bddaf26c67aa12acd35a61a6ab4a4d 584 Pfam PF00664 ABC transporter transmembrane region 19 289 3.1E-45 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Pfam PF01751 Toprim domain 3 138 1.3E-9 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Gene3D G3DSA:2.70.20.10 219 481 2.4E-157 T 01-11-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 SMART SM00493 1 130 4.2E-14 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 01-11-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Gene3D G3DSA:1.10.290.10 282 411 2.4E-157 T 01-11-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Gene3D G3DSA:1.10.460.10 164 596 2.4E-157 T 01-11-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Gene3D G3DSA:3.40.50.140 1 157 2.6E-50 T 01-11-2018 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 1.9E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 1.9E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 1.9E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 1.9E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 1.9E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Pfam PF13342 C-terminal repeat of topoisomerase 656 713 1.1E-16 T 01-11-2018 IPR025589 Topoisomerase C-terminal repeat MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 711 6.4E-191 T 01-11-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 SUPERFAMILY SSF56712 1 600 4.97E-177 T 01-11-2018 IPR023405 DNA topoisomerase, type IA, core domain MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 SMART SM00437 273 551 3.6E-84 T 01-11-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 Pfam PF01131 DNA topoisomerase 158 586 8.5E-127 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_09675 423162f506e8f19aabe4be383dc3da9f 714 SMART SM00436 130 225 3.9E-34 T 01-11-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MLA2C4_18665 54daa1492db8a42449c4d8de66cf3744 626 Pfam PF00589 Phage integrase family 307 486 8.8E-15 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_18665 54daa1492db8a42449c4d8de66cf3744 626 Gene3D G3DSA:1.10.443.10 284 501 1.4E-20 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_18665 54daa1492db8a42449c4d8de66cf3744 626 SUPERFAMILY SSF56349 158 492 5.3E-22 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 4.9E-29 T 01-11-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 197 2.3E-37 T 01-11-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 Gene3D G3DSA:1.10.287.990 21 91 3.3E-31 T 01-11-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 SUPERFAMILY SSF46609 3 92 3.67E-35 T 01-11-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 PIRSF PIRSF000349 1 208 3.4E-77 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 SUPERFAMILY SSF54719 94 204 3.01E-42 T 01-11-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 01-11-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 3.9E-23 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 3.9E-23 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.9E-23 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.9E-23 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 3.9E-23 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_28210 3047e7f44798a66fcab9a1a031a340e5 208 Gene3D G3DSA:2.40.500.20 92 208 2.8E-49 T 01-11-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 179 208 5.7E-7 T 01-11-2018 MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 21 46 6.5E-6 T 01-11-2018 MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 217 246 5.4E-9 T 01-11-2018 MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 141 170 5.9E-6 T 01-11-2018 MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 Gene3D G3DSA:2.130.10.30 17 213 5.7E-39 T 01-11-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 21 31 - T 01-11-2018 IPR000408 Regulator of chromosome condensation, RCC1 MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 Gene3D G3DSA:2.130.10.30 214 300 5.4E-16 T 01-11-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 SUPERFAMILY SSF50985 70 298 4.51E-49 T 01-11-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II MLA2C4_09400 8f9d994dea4dd325774582be139d3542 300 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 220 230 - T 01-11-2018 IPR000408 Regulator of chromosome condensation, RCC1 MLA2C4_22200 c36f074d993619b879c315d4b175e1f6 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 73 1.7E-37 T 01-11-2018 IPR020254 Protein of unknown function DUF2626 MLA2C4_22200 c36f074d993619b879c315d4b175e1f6 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 80 5.0E-38 T 01-11-2018 IPR020254 Protein of unknown function DUF2626 MLA2C4_19890 eaf4b2e052f8802b73075947343031da 83 Gene3D G3DSA:2.30.30.240 1 77 3.7E-8 T 01-11-2018 MLA2C4_19890 eaf4b2e052f8802b73075947343031da 83 Pfam PF05239 PRC-barrel domain 1 77 1.6E-12 T 01-11-2018 IPR027275 PRC-barrel domain MLA2C4_19890 eaf4b2e052f8802b73075947343031da 83 SUPERFAMILY SSF50346 1 74 4.97E-12 T 01-11-2018 IPR011033 PRC-barrel-like superfamily MLA2C4_19890 eaf4b2e052f8802b73075947343031da 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 2.7E-30 T 01-11-2018 IPR014238 Sporulation protein YlmC/YmxH MLA2C4_23460 4cb4d08b16eaadea217dd144d01b99ad 262 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 8 61 2.5E-21 T 01-11-2018 IPR025713 Motility protein B, N-terminal domain MLA2C4_23460 4cb4d08b16eaadea217dd144d01b99ad 262 Gene3D G3DSA:3.30.1330.60 89 260 3.8E-46 T 01-11-2018 IPR036737 OmpA-like domain superfamily MLA2C4_23460 4cb4d08b16eaadea217dd144d01b99ad 262 SUPERFAMILY SSF103088 135 257 6.8E-29 T 01-11-2018 IPR036737 OmpA-like domain superfamily MLA2C4_23460 4cb4d08b16eaadea217dd144d01b99ad 262 Pfam PF00691 OmpA family 148 248 3.4E-16 T 01-11-2018 IPR006665 OmpA-like domain MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 SUPERFAMILY SSF48600 5 88 2.29E-21 T 01-11-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 SUPERFAMILY SSF51569 57 352 1.1E-101 T 01-11-2018 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 1.3E-43 T 01-11-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 Gene3D G3DSA:3.20.20.70 93 356 3.1E-101 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 Gene3D G3DSA:1.20.59.10 8 92 6.0E-29 T 01-11-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 Pfam PF01817 Chorismate mutase type II 10 87 1.3E-18 T 01-11-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 Pfam PF00793 DAHP synthetase I family 110 351 1.3E-81 T 01-11-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 9.1E-123 T 01-11-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MLA2C4_15570 a4d948969ff82e39615b681e97fb23c5 358 SMART SM00830 10 89 5.1E-24 T 01-11-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MLA2C4_13435 b017ace53d117623081c276e8874dba6 241 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_13435 b017ace53d117623081c276e8874dba6 241 Pfam PF00005 ABC transporter 21 162 5.1E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_13435 b017ace53d117623081c276e8874dba6 241 SMART SM00382 30 209 2.3E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13435 b017ace53d117623081c276e8874dba6 241 Gene3D G3DSA:3.40.50.300 1 237 1.5E-65 T 01-11-2018 MLA2C4_13435 b017ace53d117623081c276e8874dba6 241 SUPERFAMILY SSF52540 4 223 6.55E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_18955 e59dfa44dc8dc77f7c7b8948eb6bae44 158 SUPERFAMILY SSF141259 7 64 1.31E-11 T 01-11-2018 IPR036101 CarD-like/TRCF domain superfamily MLA2C4_18955 e59dfa44dc8dc77f7c7b8948eb6bae44 158 Gene3D G3DSA:2.30.30.840 2 66 2.3E-25 T 01-11-2018 MLA2C4_18955 e59dfa44dc8dc77f7c7b8948eb6bae44 158 Gene3D G3DSA:1.20.58.1290 67 158 1.5E-27 T 01-11-2018 MLA2C4_18955 e59dfa44dc8dc77f7c7b8948eb6bae44 158 SMART SM01058 6 116 4.5E-32 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_18955 e59dfa44dc8dc77f7c7b8948eb6bae44 158 Pfam PF02559 CarD-like/TRCF domain 7 115 2.3E-17 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_06740 99ea0e779cd255a714582611922a8325 386 Pfam PF00589 Phage integrase family 178 357 3.2E-31 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_06740 99ea0e779cd255a714582611922a8325 386 SUPERFAMILY SSF56349 70 365 5.59E-74 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_06740 99ea0e779cd255a714582611922a8325 386 Gene3D G3DSA:1.10.443.10 171 371 3.1E-60 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_06740 99ea0e779cd255a714582611922a8325 386 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 70 123 1.0E-11 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_06740 99ea0e779cd255a714582611922a8325 386 Gene3D G3DSA:1.10.150.130 59 170 2.2E-24 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_06740 99ea0e779cd255a714582611922a8325 386 Pfam PF14657 Arm DNA-binding domain 14 54 9.1E-10 T 01-11-2018 IPR028259 AP2-like integrase, N-terminal domain MLA2C4_23065 877b39471989be33a268a0c071e2130b 309 Pfam PF00892 EamA-like transporter family 155 290 2.0E-22 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_23065 877b39471989be33a268a0c071e2130b 309 Pfam PF00892 EamA-like transporter family 7 141 1.5E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_23065 877b39471989be33a268a0c071e2130b 309 SUPERFAMILY SSF103481 192 295 3.27E-13 T 01-11-2018 MLA2C4_23065 877b39471989be33a268a0c071e2130b 309 SUPERFAMILY SSF103481 40 144 6.54E-14 T 01-11-2018 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Gene3D G3DSA:3.90.105.10 26 183 8.1E-118 T 01-11-2018 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 SMART SM00852 189 327 4.3E-38 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 7.5E-18 T 01-11-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Gene3D G3DSA:2.170.190.11 50 150 8.1E-118 T 01-11-2018 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Gene3D G3DSA:3.40.980.10 184 336 8.1E-118 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 SUPERFAMILY SSF53218 186 329 2.88E-40 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 SUPERFAMILY SSF63867 338 412 1.31E-16 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 4.3E-33 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 9.6E-40 T 01-11-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Pfam PF00994 Probable molybdopterin binding domain 189 326 8.5E-26 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 SUPERFAMILY SSF63882 9 184 8.37E-51 T 01-11-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_24565 b00f7da9d4a44b6512f61847fcf1a23d 429 Gene3D G3DSA:2.40.340.10 337 406 8.1E-118 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_08445 135f3d33136ea3e9aa827dbf31345dfd 105 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 105 4.0E-53 T 01-11-2018 MLA2C4_08445 135f3d33136ea3e9aa827dbf31345dfd 105 Pfam PF09685 Domain of unknown function (DUF4870) 6 101 4.2E-7 T 01-11-2018 IPR019109 Protein of unknown function DUF4870 MLA2C4_17835 71669c609cadf675ef2d59da4d804944 457 Pfam PF12791 Anti-sigma factor N-terminus 7 52 8.1E-13 T 01-11-2018 IPR024449 Anti-sigma factor RsgI, N-terminal MLA2C4_08430 6753564458212eafa36c2ba26eab6314 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 416 9.8E-52 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_08430 6753564458212eafa36c2ba26eab6314 451 Pfam PF01554 MatE 22 183 5.5E-28 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_08430 6753564458212eafa36c2ba26eab6314 451 Pfam PF01554 MatE 255 404 3.3E-17 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_08430 6753564458212eafa36c2ba26eab6314 451 PIRSF PIRSF006603 1 440 2.2E-73 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_26660 bb68f0dca1388e59300ded257ecb40e2 317 Gene3D G3DSA:3.40.50.12300 3 316 9.2E-130 T 01-11-2018 IPR038136 Gluconeogenesis factor superfamily MLA2C4_26660 bb68f0dca1388e59300ded257ecb40e2 317 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 316 1.1E-124 T 01-11-2018 IPR010119 Gluconeogenesis factor MLA2C4_26660 bb68f0dca1388e59300ded257ecb40e2 317 Pfam PF01933 Uncharacterised protein family UPF0052 9 294 7.2E-105 T 01-11-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 MLA2C4_26660 bb68f0dca1388e59300ded257ecb40e2 317 Hamap MF_00973 Gluconeogenesis factor. 5 317 34.151 T 01-11-2018 IPR010119 Gluconeogenesis factor MLA2C4_26660 bb68f0dca1388e59300ded257ecb40e2 317 SUPERFAMILY SSF142338 6 314 2.62E-107 T 01-11-2018 MLA2C4_16385 3ee7b6a7587df9ee40d8d3865f4951ac 439 Gene3D G3DSA:1.20.1170.10 40 323 1.5E-70 T 01-11-2018 MLA2C4_16385 3ee7b6a7587df9ee40d8d3865f4951ac 439 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 36 206 6.5E-51 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_16385 3ee7b6a7587df9ee40d8d3865f4951ac 439 SUPERFAMILY SSF58100 20 264 7.85E-44 T 01-11-2018 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 467 577 1.1E-27 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Gene3D G3DSA:1.10.8.500 184 234 3.1E-11 T 01-11-2018 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SMART SM00387 466 579 2.7E-40 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 521 531 3.1E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 576 3.1E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 517 3.1E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 539 557 3.1E-19 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Pfam PF00672 HAMP domain 186 232 2.5E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SUPERFAMILY SSF55874 409 576 9.17E-48 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SMART SM00388 353 420 5.4E-19 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SUPERFAMILY SSF55785 232 345 7.91E-8 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Gene3D G3DSA:3.30.565.10 427 578 8.5E-45 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SUPERFAMILY SSF158472 186 233 2.09E-9 T 01-11-2018 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Gene3D G3DSA:3.30.450.20 235 344 6.7E-18 T 01-11-2018 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SUPERFAMILY SSF47384 337 421 4.51E-21 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SMART SM00304 185 237 4.7E-11 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 SMART SM00091 244 313 4.1E-4 T 01-11-2018 IPR000014 PAS domain MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Gene3D G3DSA:1.10.287.130 345 425 1.0E-25 T 01-11-2018 MLA2C4_07785 629fe993a5bcae173fc4e6f2de7a5e4b 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 420 1.2E-17 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_14520 bccf324190169b789572e1be4c5a99ef 345 Pfam PF11638 DnaA N-terminal domain 94 153 4.2E-9 T 01-11-2018 IPR024633 DnaA N-terminal domain MLA2C4_14520 bccf324190169b789572e1be4c5a99ef 345 Pfam PF11638 DnaA N-terminal domain 5 58 1.2E-14 T 01-11-2018 IPR024633 DnaA N-terminal domain MLA2C4_14520 bccf324190169b789572e1be4c5a99ef 345 Pfam PF11638 DnaA N-terminal domain 192 253 2.3E-14 T 01-11-2018 IPR024633 DnaA N-terminal domain MLA2C4_14520 bccf324190169b789572e1be4c5a99ef 345 Gene3D G3DSA:3.30.300.180 1 76 5.0E-23 T 01-11-2018 IPR038454 DnaA, N-terminal domain superfamily MLA2C4_14520 bccf324190169b789572e1be4c5a99ef 345 Gene3D G3DSA:3.30.300.180 87 168 6.3E-18 T 01-11-2018 IPR038454 DnaA, N-terminal domain superfamily MLA2C4_14520 bccf324190169b789572e1be4c5a99ef 345 Gene3D G3DSA:3.30.300.180 186 267 1.9E-20 T 01-11-2018 IPR038454 DnaA, N-terminal domain superfamily MLA2C4_08785 edce85d79b890c1ae1c263a71caad400 111 SUPERFAMILY SSF54909 4 106 2.9E-31 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_08785 edce85d79b890c1ae1c263a71caad400 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 32 83 1.5E-7 T 01-11-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MLA2C4_08785 edce85d79b890c1ae1c263a71caad400 111 Gene3D G3DSA:3.30.70.100 9 101 4.8E-37 T 01-11-2018 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 6.7E-22 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 6.7E-22 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 6.7E-22 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 6.7E-22 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.752 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 01-11-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 7.1E-37 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 Gene3D G3DSA:4.10.640.10 2 77 1.5E-31 T 01-11-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 Pfam PF01084 Ribosomal protein S18 23 72 1.4E-28 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 SUPERFAMILY SSF46911 5 75 7.59E-31 T 01-11-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28400 57c05a7bc3bd3c4dbcb0f11f420a63d6 77 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 77 9.0E-24 T 01-11-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_26510 dedb85657684baf4d5e4633fc92c42ec 531 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 43 505 1.1E-194 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_26510 dedb85657684baf4d5e4633fc92c42ec 531 PIRSF PIRSF005690 28 521 3.2E-183 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 SUPERFAMILY SSF53244 310 449 1.74E-42 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 377 1.6E-10 T 01-11-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 SUPERFAMILY SSF51984 10 100 2.09E-17 T 01-11-2018 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 Gene3D G3DSA:3.90.190.20 315 448 1.9E-41 T 01-11-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 447 2.2E-134 T 01-11-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 Gene3D G3DSA:3.40.50.720 10 95 1.1E-27 T 01-11-2018 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 Pfam PF08245 Mur ligase middle domain 117 290 1.3E-31 T 01-11-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 449 35.332 T 01-11-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 SUPERFAMILY SSF53623 103 308 6.41E-50 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_20445 4aa27327ccb9994a2905bec6039a140b 450 Gene3D G3DSA:3.40.1190.10 102 308 3.9E-63 T 01-11-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MLA2C4_02200 62f9c98725f63702a66571799c9f5967 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 254 4.2E-9 T 01-11-2018 IPR005135 Endonuclease/exonuclease/phosphatase MLA2C4_02200 62f9c98725f63702a66571799c9f5967 263 SUPERFAMILY SSF56219 1 261 4.19E-36 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_02200 62f9c98725f63702a66571799c9f5967 263 Gene3D G3DSA:3.60.10.10 1 262 2.6E-77 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_03670 124fa5b2f05d34f847c77dafcaff0b85 145 Pfam PF00583 Acetyltransferase (GNAT) family 34 123 2.1E-7 T 01-11-2018 IPR000182 GNAT domain MLA2C4_03670 124fa5b2f05d34f847c77dafcaff0b85 145 Gene3D G3DSA:3.40.630.30 1 145 2.8E-30 T 01-11-2018 MLA2C4_03670 124fa5b2f05d34f847c77dafcaff0b85 145 SUPERFAMILY SSF55729 24 133 3.24E-15 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_07765 0a65b145a8ead9cd27dd7d54c59eec09 173 Gene3D G3DSA:3.40.30.10 28 173 2.3E-52 T 01-11-2018 MLA2C4_07765 0a65b145a8ead9cd27dd7d54c59eec09 173 Hamap MF_01319 Thiol-disulfide oxidoreductase ResA [resA]. 1 173 46.563 T 01-11-2018 IPR023555 Thiol-disulphide oxidoreductase ResA GO:0005886|GO:0015036|GO:0017004 MLA2C4_07765 0a65b145a8ead9cd27dd7d54c59eec09 173 Pfam PF00578 AhpC/TSA family 37 152 1.3E-37 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_07765 0a65b145a8ead9cd27dd7d54c59eec09 173 SUPERFAMILY SSF52833 8 170 2.67E-46 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 Pfam PF12727 PBP superfamily domain 90 273 2.5E-53 T 01-11-2018 IPR024370 PBP domain MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 Pfam PF12728 Helix-turn-helix domain 6 53 5.6E-16 T 01-11-2018 MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 Gene3D G3DSA:1.10.1660.10 4 55 1.3E-10 T 01-11-2018 MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 53 2.3E-19 T 01-11-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 SUPERFAMILY SSF46955 6 53 4.03E-6 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 SUPERFAMILY SSF53850 137 293 1.09E-19 T 01-11-2018 MLA2C4_01160 39188f4c1e5649bddacbad43c40e2833 306 Gene3D G3DSA:3.40.190.10 159 259 4.4E-9 T 01-11-2018 MLA2C4_13300 fb4761a34305387523ccf32e67cd3e5a 156 Pfam PF16723 Domain of unknown function (DUF5065) 2 156 2.4E-55 T 01-11-2018 IPR031998 Protein of unknown function DUF5065 MLA2C4_13300 fb4761a34305387523ccf32e67cd3e5a 156 Gene3D G3DSA:2.60.40.3720 37 156 1.4E-63 T 01-11-2018 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 PIRSF PIRSF036692 1 219 6.6E-107 T 01-11-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 Gene3D G3DSA:3.30.70.260 147 219 6.4E-16 T 01-11-2018 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 Gene3D G3DSA:3.30.1330.90 13 90 2.8E-20 T 01-11-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 SUPERFAMILY SSF143548 19 137 3.01E-32 T 01-11-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 SUPERFAMILY SSF55021 136 217 6.87E-17 T 01-11-2018 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 Pfam PF03315 Serine dehydratase beta chain 5 131 5.5E-16 T 01-11-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 Pfam PF01842 ACT domain 149 208 7.4E-12 T 01-11-2018 IPR002912 ACT domain MLA2C4_21650 9ef7ebaa2f5e26623e4cf61baa8318e0 219 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 5.9E-80 T 01-11-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MLA2C4_25920 161826b23fea5fb0eb56bfcb211ecd33 430 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 147 420 3.0E-75 T 01-11-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MLA2C4_25920 161826b23fea5fb0eb56bfcb211ecd33 430 SUPERFAMILY SSF101960 11 429 1.57E-117 T 01-11-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily MLA2C4_25920 161826b23fea5fb0eb56bfcb211ecd33 430 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 404 1.2E-61 T 01-11-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MLA2C4_07420 049c6e4c4703c40cfef91a0cde3c95b5 193 Pfam PF00694 Aconitase C-terminal domain 1 123 2.2E-36 T 01-11-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MLA2C4_07420 049c6e4c4703c40cfef91a0cde3c95b5 193 SUPERFAMILY SSF52016 1 186 1.1E-59 T 01-11-2018 MLA2C4_07420 049c6e4c4703c40cfef91a0cde3c95b5 193 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 193 40.077 T 01-11-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MLA2C4_07420 049c6e4c4703c40cfef91a0cde3c95b5 193 Gene3D G3DSA:3.20.19.10 1 171 6.6E-77 T 01-11-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MLA2C4_07420 049c6e4c4703c40cfef91a0cde3c95b5 193 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 183 1.9E-74 T 01-11-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MLA2C4_23715 c0905b1d14ad787c014dc452e2f3f941 185 Gene3D G3DSA:1.10.3210.10 4 184 2.9E-14 T 01-11-2018 MLA2C4_23715 c0905b1d14ad787c014dc452e2f3f941 185 SUPERFAMILY SSF109604 19 137 1.41E-17 T 01-11-2018 MLA2C4_23715 c0905b1d14ad787c014dc452e2f3f941 185 Pfam PF01966 HD domain 26 135 1.1E-10 T 01-11-2018 IPR006674 HD domain MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 Gene3D G3DSA:3.40.50.2300 151 325 4.6E-41 T 01-11-2018 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 Gene3D G3DSA:1.10.260.40 1 58 2.5E-21 T 01-11-2018 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 Gene3D G3DSA:3.40.50.2300 59 150 5.8E-17 T 01-11-2018 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 01-11-2018 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-6 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-6 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 SUPERFAMILY SSF47413 1 60 5.55E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 SUPERFAMILY SSF53822 61 325 8.35E-60 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 Pfam PF13377 Periplasmic binding protein-like domain 167 325 9.4E-32 T 01-11-2018 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.2E-19 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_01205 49a46a9b883c9b84a0c3735c87297065 325 SMART SM00354 1 71 5.4E-33 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_17600 91ed98b633c40222aa76c5812d0e9fa8 158 Gene3D G3DSA:3.40.630.30 2 135 4.0E-18 T 01-11-2018 MLA2C4_17600 91ed98b633c40222aa76c5812d0e9fa8 158 SUPERFAMILY SSF55729 36 139 2.44E-18 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_17600 91ed98b633c40222aa76c5812d0e9fa8 158 Pfam PF13673 Acetyltransferase (GNAT) domain 50 148 8.3E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_05315 865bd1fc2776b4559b96ad32a79125d5 160 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 156 40.511 T 01-11-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 MLA2C4_05315 865bd1fc2776b4559b96ad32a79125d5 160 Gene3D G3DSA:3.30.565.10 5 150 2.2E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05315 865bd1fc2776b4559b96ad32a79125d5 160 SUPERFAMILY SSF55874 31 135 1.83E-13 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05315 865bd1fc2776b4559b96ad32a79125d5 160 Pfam PF13581 Histidine kinase-like ATPase domain 12 140 4.1E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05315 865bd1fc2776b4559b96ad32a79125d5 160 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 157 1.0E-70 T 01-11-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 MLA2C4_20570 89b3355dea283b8eaece65b4d55023a8 344 Gene3D G3DSA:3.40.33.10 26 344 8.9E-102 T 01-11-2018 IPR035940 CAP superfamily MLA2C4_20570 89b3355dea283b8eaece65b4d55023a8 344 Pfam PF14504 CAP-associated N-terminal 60 199 2.0E-47 T 01-11-2018 IPR029410 CAP-associated domain MLA2C4_20570 89b3355dea283b8eaece65b4d55023a8 344 SUPERFAMILY SSF55797 223 341 2.35E-22 T 01-11-2018 IPR035940 CAP superfamily MLA2C4_20570 89b3355dea283b8eaece65b4d55023a8 344 Pfam PF00188 Cysteine-rich secretory protein family 230 334 1.5E-16 T 01-11-2018 IPR014044 CAP domain MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 SUPERFAMILY SSF55174 2 200 1.19E-67 T 01-11-2018 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 SMART SM01390 3 91 6.9E-47 T 01-11-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 01-11-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 Gene3D G3DSA:1.10.1050.10 6 200 2.6E-75 T 01-11-2018 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 1.3E-29 T 01-11-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 SMART SM00363 92 156 2.6E-21 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 Gene3D G3DSA:3.10.290.10 91 185 2.6E-75 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 Pfam PF01479 S4 domain 93 139 9.5E-21 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 35.826 T 01-11-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_24185 f959645834458f6b46cdf49f1bf151d0 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 6.0E-84 T 01-11-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_27810 2b9965e8a89b3a42507238c8d976b6da 135 SUPERFAMILY SSF46955 1 121 6.59E-26 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_27810 2b9965e8a89b3a42507238c8d976b6da 135 Gene3D G3DSA:1.10.1660.10 1 132 1.6E-31 T 01-11-2018 MLA2C4_27810 2b9965e8a89b3a42507238c8d976b6da 135 Pfam PF13411 MerR HTH family regulatory protein 2 70 8.7E-20 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_27810 2b9965e8a89b3a42507238c8d976b6da 135 SMART SM00422 2 72 7.6E-31 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_22780 ac7e44c703bac3a7a645fa8eeacb460d 272 Pfam PF00005 ABC transporter 18 165 2.8E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_22780 ac7e44c703bac3a7a645fa8eeacb460d 272 SUPERFAMILY SSF52540 2 227 8.42E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22780 ac7e44c703bac3a7a645fa8eeacb460d 272 Gene3D G3DSA:3.40.50.300 2 250 8.0E-65 T 01-11-2018 MLA2C4_22780 ac7e44c703bac3a7a645fa8eeacb460d 272 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_22780 ac7e44c703bac3a7a645fa8eeacb460d 272 SMART SM00382 26 215 8.5E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 Pfam PF00557 Metallopeptidase family M24 179 391 2.4E-55 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 Gene3D G3DSA:3.90.230.10 172 427 8.7E-91 T 01-11-2018 MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 122 8.0E-31 T 01-11-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 SMART SM01011 1 137 8.2E-37 T 01-11-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 SUPERFAMILY SSF53092 2 172 3.92E-37 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 Gene3D G3DSA:3.40.350.10 1 171 4.6E-66 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_09655 204b8b657574089762d23c84ba31939e 427 SUPERFAMILY SSF55920 173 415 3.53E-67 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_10640 5fb88bfd64ed591717391189ba792339 274 Pfam PF01636 Phosphotransferase enzyme family 11 238 2.4E-19 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_10640 5fb88bfd64ed591717391189ba792339 274 Gene3D G3DSA:3.90.1200.10 80 274 1.2E-57 T 01-11-2018 MLA2C4_10640 5fb88bfd64ed591717391189ba792339 274 Gene3D G3DSA:3.30.200.20 1 79 7.9E-22 T 01-11-2018 MLA2C4_10640 5fb88bfd64ed591717391189ba792339 274 SUPERFAMILY SSF56112 10 245 3.4E-30 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_21715 1dccc54f256dc46a19400d175dd7e3ae 240 Pfam PF00005 ABC transporter 17 165 3.1E-39 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_21715 1dccc54f256dc46a19400d175dd7e3ae 240 SUPERFAMILY SSF52540 1 235 1.09E-80 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21715 1dccc54f256dc46a19400d175dd7e3ae 240 Gene3D G3DSA:3.40.50.300 1 240 6.0E-81 T 01-11-2018 MLA2C4_21715 1dccc54f256dc46a19400d175dd7e3ae 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_21715 1dccc54f256dc46a19400d175dd7e3ae 240 PIRSF PIRSF039085 1 240 4.8E-115 T 01-11-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MLA2C4_21715 1dccc54f256dc46a19400d175dd7e3ae 240 SMART SM00382 26 213 3.6E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 181 35.483 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 SUPERFAMILY SSF46785 1 81 4.41E-16 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 Gene3D G3DSA:1.10.10.10 2 83 3.4E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 SUPERFAMILY SSF46785 87 159 7.07E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 168 9.9E-57 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 PIRSF PIRSF019345 1 184 6.6E-56 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 184 2.4E-52 T 01-11-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MLA2C4_21215 6b1a31fe476701cfc60efe24ee8d1ad9 190 Gene3D G3DSA:1.10.10.10 84 179 6.8E-38 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09615 26af750d48e92142d8591e74646a9211 315 SUPERFAMILY SSF88659 11 47 1.9E-7 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_09615 26af750d48e92142d8591e74646a9211 315 SUPERFAMILY SSF100950 56 312 1.54E-74 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_09615 26af750d48e92142d8591e74646a9211 315 Gene3D G3DSA:1.10.10.60 1 52 2.7E-22 T 01-11-2018 MLA2C4_09615 26af750d48e92142d8591e74646a9211 315 Pfam PF04545 Sigma-70, region 4 14 47 1.4E-6 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_09615 26af750d48e92142d8591e74646a9211 315 Gene3D G3DSA:3.40.50.1360 53 311 5.8E-84 T 01-11-2018 MLA2C4_09615 26af750d48e92142d8591e74646a9211 315 Pfam PF04198 Putative sugar-binding domain 57 310 3.3E-77 T 01-11-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MLA2C4_19150 80c2c40e562b422bb0cf1e02d08fabe4 73 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 5.4E-30 T 01-11-2018 IPR005359 Protein with unknown function UPF0154 MLA2C4_19150 80c2c40e562b422bb0cf1e02d08fabe4 73 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 41 3.0E-5 T 01-11-2018 IPR005359 Protein with unknown function UPF0154 MLA2C4_19150 80c2c40e562b422bb0cf1e02d08fabe4 73 Hamap MF_00363 UPF0154 protein . 2 72 21.847 T 01-11-2018 IPR005359 Protein with unknown function UPF0154 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 SMART SM00345 18 77 2.0E-21 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.5E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.5E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 Pfam PF00155 Aminotransferase class I and II 106 459 1.6E-27 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 Gene3D G3DSA:1.10.10.10 4 88 3.2E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 SUPERFAMILY SSF46785 10 81 1.87E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 Gene3D G3DSA:3.40.640.10 93 459 6.2E-118 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 2.2E-19 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_01695 a6f7469732be4b92d30c28a616ce499d 470 SUPERFAMILY SSF53383 82 465 2.81E-85 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_05400 0a718e731bbb1f5b266fc402aecfbfb1 46 Pfam PF11121 Protein of unknown function (DUF2639) 2 39 1.1E-20 T 01-11-2018 IPR022580 Protein of unknown function DUF2639 MLA2C4_05400 0a718e731bbb1f5b266fc402aecfbfb1 46 ProDom PD049467 YFLJ 1 43 3.0E-17 T 01-11-2018 IPR022580 Protein of unknown function DUF2639 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.7E-20 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 Gene3D G3DSA:1.10.10.10 1 87 8.5E-27 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 SUPERFAMILY SSF46785 1 85 1.27E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-10 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-10 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-10 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 SUPERFAMILY SSF53850 99 292 1.01E-37 T 01-11-2018 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 Gene3D G3DSA:3.40.190.290 92 293 4.9E-51 T 01-11-2018 MLA2C4_27005 d121cb55982d55c89f90c6ead0628a40 294 Pfam PF03466 LysR substrate binding domain 98 288 1.3E-40 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 1.1E-52 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 01-11-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 SUPERFAMILY SSF53790 1 247 5.63E-84 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 Gene3D G3DSA:3.40.1010.10 1 117 3.5E-45 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 7.1E-102 T 01-11-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 Gene3D G3DSA:3.30.950.10 118 257 6.5E-51 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MLA2C4_07535 329b5fd6643334005941184e93a01aa3 258 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 01-11-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MLA2C4_19110 aefdd4e447335332da51d9dbdecb274c 68 Pfam PF13043 Domain of unknown function (DUF3903) 25 64 3.7E-29 T 01-11-2018 IPR025000 Protein of unknown function DUF3903 MLA2C4_26230 76a8955977439bac5ef7a11c9113aa0d 272 SUPERFAMILY SSF53335 10 239 1.26E-28 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_26230 76a8955977439bac5ef7a11c9113aa0d 272 Gene3D G3DSA:3.40.50.150 40 262 5.3E-26 T 01-11-2018 MLA2C4_26230 76a8955977439bac5ef7a11c9113aa0d 272 Pfam PF08241 Methyltransferase domain 66 155 7.6E-12 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_23535 f3f63061d305826683b15ae512e6898e 294 SUPERFAMILY SSF49842 202 273 7.87E-5 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_23535 f3f63061d305826683b15ae512e6898e 294 Pfam PF01391 Collagen triple helix repeat (20 copies) 37 92 1.5E-8 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 260 8.6E-17 T 01-11-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 SUPERFAMILY SSF51735 2 157 1.43E-21 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 PIRSF PIRSF000193 1 265 1.4E-64 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 Gene3D G3DSA:1.10.3730.10 161 262 1.1E-16 T 01-11-2018 MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 SUPERFAMILY SSF48179 159 262 1.17E-19 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 Gene3D G3DSA:3.40.50.720 1 160 2.2E-30 T 01-11-2018 MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 2.1E-15 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MLA2C4_22600 1785605bb6a5a2b58fc340d5aa916088 275 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_23245 e7b7ba2edcd73d889413a5bd151a7eb4 341 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 9 320 5.5E-134 T 01-11-2018 IPR014253 Spore coat protein YsxE MLA2C4_23245 e7b7ba2edcd73d889413a5bd151a7eb4 341 Gene3D G3DSA:3.30.200.20 3 95 7.4E-15 T 01-11-2018 MLA2C4_23245 e7b7ba2edcd73d889413a5bd151a7eb4 341 Pfam PF01636 Phosphotransferase enzyme family 34 245 1.6E-8 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_23245 e7b7ba2edcd73d889413a5bd151a7eb4 341 SUPERFAMILY SSF56112 12 302 2.19E-21 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_23245 e7b7ba2edcd73d889413a5bd151a7eb4 341 Gene3D G3DSA:3.90.1200.10 99 325 3.8E-22 T 01-11-2018 MLA2C4_26150 01f335dddf799a22a75e2eb6c000cdc7 297 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 32 232 8.1E-59 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_26150 01f335dddf799a22a75e2eb6c000cdc7 297 PIRSF PIRSF006483 13 297 7.3E-98 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_26150 01f335dddf799a22a75e2eb6c000cdc7 297 Gene3D G3DSA:3.30.70.120 206 285 3.0E-19 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_26150 01f335dddf799a22a75e2eb6c000cdc7 297 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 238 292 8.4E-22 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 SMART SM00481 4 71 1.4E-22 T 01-11-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Gene3D G3DSA:3.20.20.140 1 260 2.3E-85 T 01-11-2018 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Pfam PF02811 PHP domain 5 164 3.6E-37 T 01-11-2018 IPR004013 PHP domain GO:0003824 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 983 0.0 T 01-11-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Gene3D G3DSA:1.10.10.1600 415 491 5.8E-23 T 01-11-2018 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Gene3D G3DSA:1.10.150.870 753 848 1.7E-5 T 01-11-2018 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 SUPERFAMILY SSF89550 2 254 1.16E-16 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 283 705 1.0E-173 T 01-11-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Pfam PF01336 OB-fold nucleic acid binding domain 956 1021 5.0E-8 T 01-11-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MLA2C4_23920 668a031ea604a29822a238b657a712b8 1108 Pfam PF14579 Helix-hairpin-helix motif 778 865 1.0E-18 T 01-11-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 1.2E-29 T 01-11-2018 IPR020069 Ribosomal protein L9, C-terminal MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.983 T 01-11-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.1E-50 T 01-11-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 Gene3D G3DSA:3.10.430.100 60 148 7.3E-32 T 01-11-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 SUPERFAMILY SSF55653 57 147 6.93E-28 T 01-11-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 1.0E-21 T 01-11-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 01-11-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 SUPERFAMILY SSF55658 1 56 6.98E-18 T 01-11-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MLA2C4_28385 e5434c08ba39ab420e6b5ed3749a4d0f 148 Gene3D G3DSA:3.40.5.10 1 52 8.1E-25 T 01-11-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22420 15e92be24bf27f4fa9c90042242fe7f3 235 Gene3D G3DSA:3.40.50.150 1 163 7.8E-53 T 01-11-2018 MLA2C4_22420 15e92be24bf27f4fa9c90042242fe7f3 235 PIRSF PIRSF018637 4 235 1.7E-82 T 01-11-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 MLA2C4_22420 15e92be24bf27f4fa9c90042242fe7f3 235 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 231 7.5E-72 T 01-11-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 MLA2C4_22420 15e92be24bf27f4fa9c90042242fe7f3 235 SUPERFAMILY SSF53335 10 105 1.71E-7 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_09335 f2f8e320c1fa2b6d4010c7a1656b8cd1 184 SUPERFAMILY SSF50242 28 182 9.61E-26 T 01-11-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 Gene3D G3DSA:3.40.50.1100 15 315 2.6E-110 T 01-11-2018 MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 Gene3D G3DSA:3.40.50.1100 57 156 2.6E-110 T 01-11-2018 MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 TIGRFAM TIGR02079 THD1: threonine dehydratase 13 420 1.1E-194 T 01-11-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 314 2.6E-76 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 Gene3D G3DSA:3.40.1020.10 316 420 7.4E-10 T 01-11-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 SUPERFAMILY SSF53686 11 363 1.07E-101 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 327 418 4.7E-26 T 01-11-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MLA2C4_09465 9a061fadcf433a7fddea62f00815dc42 420 SUPERFAMILY SSF55021 337 415 9.61E-11 T 01-11-2018 MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 474 1.1E-21 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 10 483 49.649 T 01-11-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 Gene3D G3DSA:3.30.300.310 390 487 1.4E-35 T 01-11-2018 MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 SUPERFAMILY SSF56801 7 486 8.63E-139 T 01-11-2018 MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 Pfam PF00501 AMP-binding enzyme 16 392 8.6E-90 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 35 480 6.1E-147 T 01-11-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 MLA2C4_25255 dfea62ae7715a6444f9f9771e7a672d2 487 Gene3D G3DSA:3.40.50.12780 5 389 3.2E-122 T 01-11-2018 MLA2C4_12285 7e0757324322abb54de37b0280c1b5a0 627 PIRSF PIRSF018968 1 622 6.8E-61 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_12285 7e0757324322abb54de37b0280c1b5a0 627 Pfam PF02687 FtsX-like permease family 84 179 2.3E-9 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 SMART SM00829 10 322 5.5E-62 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.9E-10 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 Gene3D G3DSA:3.40.50.720 122 267 1.5E-102 T 01-11-2018 MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 SUPERFAMILY SSF51735 111 272 4.57E-45 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 01-11-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 Pfam PF00107 Zinc-binding dehydrogenase 150 278 1.6E-31 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 SUPERFAMILY SSF50129 1 144 2.13E-38 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_10750 d28adfe4ca90ae009554a1e0b1a39a0e 328 Gene3D G3DSA:3.90.180.10 10 318 1.5E-102 T 01-11-2018 MLA2C4_03755 ed2dc6ad339ac24532dc0b2dd992146e 85 Pfam PF04023 FeoA domain 8 76 4.5E-19 T 01-11-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MLA2C4_03755 ed2dc6ad339ac24532dc0b2dd992146e 85 SUPERFAMILY SSF50037 10 76 1.08E-18 T 01-11-2018 IPR008988 Transcriptional repressor, C-terminal MLA2C4_03755 ed2dc6ad339ac24532dc0b2dd992146e 85 Gene3D G3DSA:2.30.30.90 4 79 1.3E-23 T 01-11-2018 IPR038157 Ferrous iron transporter, core domain MLA2C4_03755 ed2dc6ad339ac24532dc0b2dd992146e 85 SMART SM00899 7 79 3.4E-20 T 01-11-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 11 290 3.5E-66 T 01-11-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 SUPERFAMILY SSF48239 296 614 1.13E-83 T 01-11-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 SUPERFAMILY SSF48239 37 293 1.05E-40 T 01-11-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 13 611 1.4E-115 T 01-11-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 Gene3D G3DSA:1.50.10.20 16 611 1.7E-187 T 01-11-2018 MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 Gene3D G3DSA:1.50.10.20 32 298 1.7E-187 T 01-11-2018 MLA2C4_18465 f2fb3a96090eeca65365d2eeade8a266 617 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 300 612 1.9E-96 T 01-11-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 MLA2C4_02585 b7ef54699c65119b1f03c3cdddc1a228 203 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 8 201 4.3E-45 T 01-11-2018 IPR014205 Sporulation protein YtaF MLA2C4_02585 b7ef54699c65119b1f03c3cdddc1a228 203 Pfam PF02659 Putative manganese efflux pump 41 200 1.1E-12 T 01-11-2018 IPR003810 Putative manganese efflux pump MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 SMART SM00387 295 403 6.9E-17 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 SUPERFAMILY SSF47384 185 248 4.51E-9 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 400 6.8E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 6.8E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 6.8E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 361 6.8E-7 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 401 2.3E-15 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 SUPERFAMILY SSF55874 254 401 9.17E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 SMART SM00388 191 253 0.0095 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 Gene3D G3DSA:3.30.565.10 254 404 9.0E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_24850 ef10f4cbedf2408b48cd7413fd670f5c 418 Gene3D G3DSA:1.10.287.130 194 249 2.8E-9 T 01-11-2018 MLA2C4_02565 144cd4100f3ef1de9a5d0d9dcd42cfca 84 Pfam PF00364 Biotin-requiring enzyme 10 73 6.3E-5 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_02565 144cd4100f3ef1de9a5d0d9dcd42cfca 84 Gene3D G3DSA:2.40.50.100 5 76 3.8E-8 T 01-11-2018 MLA2C4_02565 144cd4100f3ef1de9a5d0d9dcd42cfca 84 SUPERFAMILY SSF51230 7 74 3.0E-7 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_20295 96437a71b7f71bb96b428828d7d57fae 210 Pfam PF00156 Phosphoribosyl transferase domain 44 155 4.1E-19 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_20295 96437a71b7f71bb96b428828d7d57fae 210 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 210 30.084 T 01-11-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_20295 96437a71b7f71bb96b428828d7d57fae 210 Gene3D G3DSA:3.40.50.2020 1 210 9.8E-68 T 01-11-2018 MLA2C4_20295 96437a71b7f71bb96b428828d7d57fae 210 SUPERFAMILY SSF53271 9 204 1.44E-51 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_20295 96437a71b7f71bb96b428828d7d57fae 210 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 8 175 9.7E-50 T 01-11-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MLA2C4_21695 5ec4cb1704610ec74fb9a5ac2c50c798 181 SUPERFAMILY SSF55729 1 179 3.0E-39 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21695 5ec4cb1704610ec74fb9a5ac2c50c798 181 Gene3D G3DSA:3.40.630.30 3 181 8.5E-42 T 01-11-2018 MLA2C4_21695 5ec4cb1704610ec74fb9a5ac2c50c798 181 Pfam PF13302 Acetyltransferase (GNAT) domain 9 155 1.0E-18 T 01-11-2018 IPR000182 GNAT domain MLA2C4_07140 773ee8231fc407a8c18f7cd31330f527 200 Gene3D G3DSA:3.40.50.1240 1 195 1.3E-5 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_07140 773ee8231fc407a8c18f7cd31330f527 200 SUPERFAMILY SSF53254 54 189 2.78E-14 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_18565 100e5fa9df8b9c0ca70d3c761a601e99 699 Gene3D G3DSA:3.40.50.410 32 201 1.3E-8 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily MLA2C4_18565 100e5fa9df8b9c0ca70d3c761a601e99 699 SUPERFAMILY SSF53300 34 178 8.49E-8 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily MLA2C4_01780 0a166f2442677e910363676432ea8413 471 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 456 1.2E-168 T 01-11-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MLA2C4_01780 0a166f2442677e910363676432ea8413 471 SUPERFAMILY SSF56235 12 239 1.97E-71 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_01780 0a166f2442677e910363676432ea8413 471 Gene3D G3DSA:3.60.20.10 12 457 9.4E-168 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_01780 0a166f2442677e910363676432ea8413 471 Pfam PF00156 Phosphoribosyl transferase domain 268 381 5.0E-8 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_01780 0a166f2442677e910363676432ea8413 471 PIRSF PIRSF000485 8 471 1.0E-185 T 01-11-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MLA2C4_01780 0a166f2442677e910363676432ea8413 471 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 455 47.598 T 01-11-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MLA2C4_01780 0a166f2442677e910363676432ea8413 471 SUPERFAMILY SSF53271 246 463 2.36E-77 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_01780 0a166f2442677e910363676432ea8413 471 Gene3D G3DSA:3.40.50.2020 270 434 9.4E-168 T 01-11-2018 MLA2C4_01780 0a166f2442677e910363676432ea8413 471 Pfam PF13537 Glutamine amidotransferase domain 93 208 8.0E-22 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain MLA2C4_02535 a5fef2c0e29fe83e53579d5f62cd9ea9 260 Gene3D G3DSA:3.20.20.370 19 260 5.8E-98 T 01-11-2018 MLA2C4_02535 a5fef2c0e29fe83e53579d5f62cd9ea9 260 SUPERFAMILY SSF88713 45 255 3.34E-66 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_02535 a5fef2c0e29fe83e53579d5f62cd9ea9 260 Pfam PF01522 Polysaccharide deacetylase 64 185 1.2E-34 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_02535 a5fef2c0e29fe83e53579d5f62cd9ea9 260 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 32 254 3.3E-115 T 01-11-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 Pfam PF00107 Zinc-binding dehydrogenase 164 277 4.7E-17 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 SUPERFAMILY SSF51735 121 294 2.25E-35 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 Gene3D G3DSA:3.90.180.10 23 329 3.0E-118 T 01-11-2018 MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 331 1.8E-139 T 01-11-2018 IPR014188 Acrylyl-CoA reductase AcuI MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 92 1.6E-5 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 SMART SM00829 12 329 1.3E-7 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 Gene3D G3DSA:3.40.50.720 131 299 3.0E-118 T 01-11-2018 MLA2C4_04320 2cbaf8b3ec0cd368e3545a18ae95c6b7 332 SUPERFAMILY SSF50129 6 150 1.49E-40 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_25880 18ffc2e1113e8180641f099e18a513bb 327 Pfam PF01551 Peptidase family M23 203 301 2.0E-19 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_25880 18ffc2e1113e8180641f099e18a513bb 327 SUPERFAMILY SSF51261 114 314 4.45E-36 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_25880 18ffc2e1113e8180641f099e18a513bb 327 Gene3D G3DSA:2.70.70.10 113 326 8.3E-57 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 01-11-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 289 6.5E-110 T 01-11-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 SUPERFAMILY SSF51569 2 289 2.72E-103 T 01-11-2018 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 4.9E-33 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 4.9E-33 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 4.9E-33 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 4.9E-33 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 63.319 T 01-11-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 SMART SM01130 3 291 2.7E-138 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 PIRSF PIRSF001365 1 292 5.4E-98 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 Gene3D G3DSA:3.20.20.70 1 292 4.2E-125 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 7.6E-108 T 01-11-2018 IPR002220 DapA-like GO:0016829 MLA2C4_19865 aa03ccd487ceed731aa590f136707346 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 01-11-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MLA2C4_00515 0f2d457525480c59c4b87afa83f216c0 182 PIRSF PIRSF015034 1 182 3.1E-62 T 01-11-2018 IPR025542 YacH protein MLA2C4_00515 0f2d457525480c59c4b87afa83f216c0 182 SUPERFAMILY SSF46600 138 175 2.09E-6 T 01-11-2018 IPR036876 UVR domain superfamily MLA2C4_00515 0f2d457525480c59c4b87afa83f216c0 182 Pfam PF02151 UvrB/uvrC motif 139 174 4.7E-7 T 01-11-2018 IPR001943 UVR domain GO:0005515 MLA2C4_18585 4578a414f05b647de0b168f6ae8cbde6 239 Pfam PF13649 Methyltransferase domain 41 133 2.5E-17 T 01-11-2018 MLA2C4_18585 4578a414f05b647de0b168f6ae8cbde6 239 SUPERFAMILY SSF53335 12 237 6.63E-35 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_18585 4578a414f05b647de0b168f6ae8cbde6 239 Gene3D G3DSA:3.40.50.150 4 222 9.8E-36 T 01-11-2018 MLA2C4_17125 c0a4640c173ec5c99c9d80361bea112a 355 Gene3D G3DSA:3.20.20.80 28 355 2.1E-43 T 01-11-2018 MLA2C4_17125 c0a4640c173ec5c99c9d80361bea112a 355 SUPERFAMILY SSF51445 51 330 4.53E-15 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 SUPERFAMILY SSF47203 240 380 4.35E-23 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 Gene3D G3DSA:2.40.110.10 124 228 3.1E-19 T 01-11-2018 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 SUPERFAMILY SSF56645 4 220 8.12E-39 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 Gene3D G3DSA:1.20.140.10 240 379 1.8E-25 T 01-11-2018 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 217 1.3E-16 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 360 1.1E-12 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 PIRSF PIRSF016578 139 381 2.6E-15 T 01-11-2018 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 PIRSF PIRSF016578 2 111 1.1E-11 T 01-11-2018 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 Gene3D G3DSA:1.10.540.10 5 123 7.6E-20 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MLA2C4_16250 d859ad744f134d95cd171980ad15b9e5 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 95 1.1E-8 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 Gene3D G3DSA:1.10.340.30 126 250 2.3E-42 T 01-11-2018 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 234 258 - T 01-11-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 54 133 2.9E-6 T 01-11-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 SUPERFAMILY SSF48150 116 302 1.22E-45 T 01-11-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 SMART SM00478 138 303 1.0E-26 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 Gene3D G3DSA:1.10.1670.40 106 301 2.3E-42 T 01-11-2018 MLA2C4_19545 489f37e1dd5284aebb2e6cffc1517a1a 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 137 286 9.5E-15 T 01-11-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MLA2C4_19805 4e9a79695057f7b112c11cbf410f5f12 428 Gene3D G3DSA:3.30.830.10 7 237 2.1E-61 T 01-11-2018 MLA2C4_19805 4e9a79695057f7b112c11cbf410f5f12 428 Pfam PF05193 Peptidase M16 inactive domain 181 361 7.9E-20 T 01-11-2018 IPR007863 Peptidase M16, C-terminal MLA2C4_19805 4e9a79695057f7b112c11cbf410f5f12 428 SUPERFAMILY SSF63411 13 219 6.98E-42 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_19805 4e9a79695057f7b112c11cbf410f5f12 428 Gene3D G3DSA:3.30.830.10 238 426 7.4E-46 T 01-11-2018 MLA2C4_19805 4e9a79695057f7b112c11cbf410f5f12 428 SUPERFAMILY SSF63411 243 426 1.5E-20 T 01-11-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MLA2C4_19805 4e9a79695057f7b112c11cbf410f5f12 428 Pfam PF00675 Insulinase (Peptidase family M16) 63 150 5.7E-16 T 01-11-2018 IPR011765 Peptidase M16, N-terminal MLA2C4_23365 d6d32624533c8106abf23713f8c80554 202 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 197 50.095 T 01-11-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 MLA2C4_23365 d6d32624533c8106abf23713f8c80554 202 Gene3D G3DSA:3.90.950.10 1 200 2.0E-79 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MLA2C4_23365 d6d32624533c8106abf23713f8c80554 202 SUPERFAMILY SSF52972 1 196 1.36E-71 T 01-11-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MLA2C4_23365 d6d32624533c8106abf23713f8c80554 202 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 194 2.3E-63 T 01-11-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MLA2C4_23365 d6d32624533c8106abf23713f8c80554 202 Pfam PF01725 Ham1 family 4 193 9.0E-61 T 01-11-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 Pfam PF00005 ABC transporter 23 125 8.3E-13 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 SUPERFAMILY SSF52540 4 196 1.22E-38 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 Gene3D G3DSA:3.40.50.300 87 207 7.8E-31 T 01-11-2018 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 Pfam PF00005 ABC transporter 304 428 1.1E-19 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 SUPERFAMILY SSF52540 274 486 1.48E-42 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 SMART SM00382 312 473 2.1E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 SMART SM00382 28 177 2.4E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 Gene3D G3DSA:3.40.50.300 2 84 6.8E-14 T 01-11-2018 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 Gene3D G3DSA:3.40.50.300 279 491 2.4E-53 T 01-11-2018 MLA2C4_26790 20089dd8dbfa834d785f92db2984ff91 544 Pfam PF12848 ABC transporter 164 268 3.1E-6 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_07290 770e49504348c35d044e10a5216f2d4d 148 TIGRFAM TIGR01753 flav_short: flavodoxin 6 144 5.2E-45 T 01-11-2018 IPR010087 Flavodoxin, short chain GO:0010181 MLA2C4_07290 770e49504348c35d044e10a5216f2d4d 148 Gene3D G3DSA:3.40.50.360 1 147 9.6E-35 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_07290 770e49504348c35d044e10a5216f2d4d 148 Pfam PF00258 Flavodoxin 7 138 1.2E-26 T 01-11-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MLA2C4_07290 770e49504348c35d044e10a5216f2d4d 148 SUPERFAMILY SSF52218 3 147 2.8E-39 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 Gene3D G3DSA:1.10.357.10 10 200 6.4E-36 T 01-11-2018 MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 SUPERFAMILY SSF48498 97 200 4.14E-10 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.9E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.9E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 3.0E-13 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 SUPERFAMILY SSF46689 13 91 9.23E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_09785 6139ccb681abacf4be5e63c5a59942e5 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 Pfam PF04055 Radical SAM superfamily 64 223 9.3E-16 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 SUPERFAMILY SSF102114 20 287 7.98E-66 T 01-11-2018 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 PIRSF PIRSF005963 1 298 1.8E-136 T 01-11-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 146.414 T 01-11-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 5 45 1.9E-10 T 01-11-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 SMART SM00729 57 265 2.6E-15 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 Gene3D G3DSA:3.20.20.70 18 268 5.4E-26 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_25875 fad7fad30f537e0ff593351e93d1f656 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 2 292 2.9E-121 T 01-11-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MLA2C4_05725 9be733fffedb961e6d5781ba15d66a7b 788 Gene3D G3DSA:3.60.10.10 491 783 8.8E-42 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_05725 9be733fffedb961e6d5781ba15d66a7b 788 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 156 222 1.4E-18 T 01-11-2018 MLA2C4_05725 9be733fffedb961e6d5781ba15d66a7b 788 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 494 775 1.7E-8 T 01-11-2018 IPR005135 Endonuclease/exonuclease/phosphatase MLA2C4_05725 9be733fffedb961e6d5781ba15d66a7b 788 SUPERFAMILY SSF56219 486 786 2.49E-31 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_03000 48da00171282c4be6f6aea874a6895b8 230 Pfam PF00072 Response regulator receiver domain 7 117 1.6E-23 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03000 48da00171282c4be6f6aea874a6895b8 230 SUPERFAMILY SSF52172 5 151 6.55E-34 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_03000 48da00171282c4be6f6aea874a6895b8 230 PIRSF PIRSF006171 3 230 9.3E-83 T 01-11-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 MLA2C4_03000 48da00171282c4be6f6aea874a6895b8 230 Gene3D G3DSA:3.40.50.2300 2 148 5.6E-29 T 01-11-2018 MLA2C4_03000 48da00171282c4be6f6aea874a6895b8 230 SMART SM00448 5 118 4.8E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_27910 43d12aefa3a422f63c300f6f6404004f 410 Gene3D G3DSA:1.10.150.130 41 155 2.0E-12 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_27910 43d12aefa3a422f63c300f6f6404004f 410 SUPERFAMILY SSF56349 44 391 4.12E-33 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_27910 43d12aefa3a422f63c300f6f6404004f 410 Pfam PF00589 Phage integrase family 198 384 6.4E-21 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_27910 43d12aefa3a422f63c300f6f6404004f 410 Gene3D G3DSA:1.10.443.10 188 407 3.0E-36 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 SMART SM00418 16 93 1.7E-12 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 Gene3D G3DSA:1.10.10.10 3 94 5.7E-15 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 SUPERFAMILY SSF46785 2 93 6.25E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 4.4E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 4.4E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 4.4E-10 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_10190 4064e7e90a81962a69e15cdc7652fc92 102 Pfam PF12840 Helix-turn-helix domain 17 69 1.3E-6 T 01-11-2018 MLA2C4_18185 36752665e9606c99cbda47d2c010e8b4 314 SUPERFAMILY SSF51695 36 311 5.23E-73 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_18185 36752665e9606c99cbda47d2c010e8b4 314 Gene3D G3DSA:3.20.20.190 23 314 3.2E-127 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_18185 36752665e9606c99cbda47d2c010e8b4 314 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 305 2.3E-50 T 01-11-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MLA2C4_06025 19b16c1dc56e712699e9d9065427cecb 68 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 68 3.0E-21 T 01-11-2018 IPR024255 Spore germination GerPB MLA2C4_06025 19b16c1dc56e712699e9d9065427cecb 68 Pfam PF10803 Spore germination GerPB 1 48 5.4E-24 T 01-11-2018 IPR024255 Spore germination GerPB MLA2C4_17220 510b3d3665d7538a1167428125c3d3fa 136 Pfam PF14106 Domain of unknown function (DUF4279) 7 131 9.7E-31 T 01-11-2018 IPR025459 Protein of unknown function DUF4279 MLA2C4_22765 65fe957b7a07163cae215e151a05d069 152 Pfam PF13508 Acetyltransferase (GNAT) domain 57 128 7.3E-10 T 01-11-2018 IPR000182 GNAT domain MLA2C4_22765 65fe957b7a07163cae215e151a05d069 152 SUPERFAMILY SSF55729 20 130 2.79E-19 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_22765 65fe957b7a07163cae215e151a05d069 152 Gene3D G3DSA:3.40.630.30 13 139 6.8E-23 T 01-11-2018 MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 Pfam PF08274 PhnA Zinc-Ribbon 3 31 3.0E-17 T 01-11-2018 IPR013987 PhnA protein, N-terminal MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 Pfam PF03831 PhnA domain 46 113 6.5E-34 T 01-11-2018 IPR013988 PhnA protein, C-terminal MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 Gene3D G3DSA:2.20.25.10 1 42 1.2E-20 T 01-11-2018 MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 SUPERFAMILY SSF82057 41 113 6.87E-29 T 01-11-2018 MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 SUPERFAMILY SSF57783 3 36 1.07E-14 T 01-11-2018 MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 Gene3D G3DSA:2.30.30.40 43 113 3.1E-35 T 01-11-2018 MLA2C4_25735 3077fa09ce377e7f5fc9d62d0136dc43 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 113 1.0E-51 T 01-11-2018 IPR004624 PhnA protein MLA2C4_02465 accf230ba8f401026a77971603b08480 316 SUPERFAMILY SSF103481 54 157 1.01E-12 T 01-11-2018 MLA2C4_02465 accf230ba8f401026a77971603b08480 316 SUPERFAMILY SSF103481 213 304 1.96E-10 T 01-11-2018 MLA2C4_02465 accf230ba8f401026a77971603b08480 316 Pfam PF00892 EamA-like transporter family 14 154 4.3E-16 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_02465 accf230ba8f401026a77971603b08480 316 Pfam PF00892 EamA-like transporter family 167 301 1.3E-16 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_04785 6446644d5cccf8d497ada4d871f0ae18 506 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 494 6.6E-23 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MLA2C4_04785 6446644d5cccf8d497ada4d871f0ae18 506 PIRSF PIRSF038958 1 506 5.9E-84 T 01-11-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type MLA2C4_04785 6446644d5cccf8d497ada4d871f0ae18 506 Pfam PF01943 Polysaccharide biosynthesis protein 6 299 3.0E-29 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 SUPERFAMILY SSF52788 1 148 3.53E-47 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 6.7E-42 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 Gene3D G3DSA:3.40.50.2300 1 154 5.9E-60 T 01-11-2018 MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 SMART SM00226 2 147 1.5E-53 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 5.4E-17 T 01-11-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 5.4E-17 T 01-11-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MLA2C4_02445 bba2b73811565b885e0b943efc76302f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 5.4E-17 T 01-11-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MLA2C4_19425 1f982b6c2e218adced8413a42136a188 387 Gene3D G3DSA:3.40.50.1970 1 184 2.7E-55 T 01-11-2018 MLA2C4_19425 1f982b6c2e218adced8413a42136a188 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MLA2C4_19425 1f982b6c2e218adced8413a42136a188 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 378 6.7E-100 T 01-11-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MLA2C4_19425 1f982b6c2e218adced8413a42136a188 387 SUPERFAMILY SSF56796 1 385 1.24E-117 T 01-11-2018 MLA2C4_19425 1f982b6c2e218adced8413a42136a188 387 Gene3D G3DSA:1.20.1090.10 185 386 2.8E-46 T 01-11-2018 MLA2C4_19425 1f982b6c2e218adced8413a42136a188 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 SUPERFAMILY SSF53067 9 129 1.38E-27 T 01-11-2018 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 SUPERFAMILY SSF53067 132 307 1.65E-40 T 01-11-2018 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 Gene3D G3DSA:3.30.420.40 2 112 3.3E-23 T 01-11-2018 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 Pfam PF02541 Ppx/GppA phosphatase family 22 307 3.8E-49 T 01-11-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 9 305 2.1E-93 T 01-11-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 Gene3D G3DSA:3.30.420.150 113 303 1.0E-53 T 01-11-2018 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 Gene3D G3DSA:1.10.3210.10 328 509 5.4E-27 T 01-11-2018 MLA2C4_20880 7a32df426e39d47b33e740b572d4db4c 512 SUPERFAMILY SSF109604 316 509 1.82E-24 T 01-11-2018 MLA2C4_25730 2d05609bb221311de1bba2ff2f3217e7 265 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 251 3.4E-84 T 01-11-2018 IPR005226 UPF0014 family MLA2C4_25730 2d05609bb221311de1bba2ff2f3217e7 265 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 257 4.7E-56 T 01-11-2018 IPR005226 UPF0014 family MLA2C4_27135 3fbb84d37c03829f71ba1d1de4893b88 161 PIRSF PIRSF019083 1 161 3.4E-54 T 01-11-2018 IPR016747 Phosphotransbutyrylase MLA2C4_27135 3fbb84d37c03829f71ba1d1de4893b88 161 Pfam PF04892 VanZ like family 7 154 5.9E-23 T 01-11-2018 IPR006976 VanZ-like MLA2C4_23135 31c753629b21c745cf5f8dc4e6efc744 258 Pfam PF00005 ABC transporter 24 172 2.5E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_23135 31c753629b21c745cf5f8dc4e6efc744 258 SMART SM00382 33 221 1.1E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23135 31c753629b21c745cf5f8dc4e6efc744 258 Gene3D G3DSA:3.40.50.300 1 252 2.2E-66 T 01-11-2018 MLA2C4_23135 31c753629b21c745cf5f8dc4e6efc744 258 SUPERFAMILY SSF52540 3 225 1.98E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 Gene3D G3DSA:2.40.500.20 92 203 7.4E-51 T 01-11-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 SUPERFAMILY SSF54719 90 201 3.14E-47 T 01-11-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 SUPERFAMILY SSF46609 2 92 4.45E-38 T 01-11-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 PIRSF PIRSF000349 1 203 2.3E-85 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 5.6E-33 T 01-11-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.2E-27 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 1.2E-27 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 1.2E-27 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.2E-27 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 1.2E-27 T 01-11-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 01-11-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 Gene3D G3DSA:1.10.287.990 21 91 2.4E-32 T 01-11-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_22345 4f00058fdcbb234ec8de03747b5b9a2f 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 198 9.4E-42 T 01-11-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MLA2C4_00745 3a58915a4d26a51e2837a10f56cbee63 132 Gene3D G3DSA:3.30.1370.30 4 74 2.8E-34 T 01-11-2018 MLA2C4_00745 3a58915a4d26a51e2837a10f56cbee63 132 Gene3D G3DSA:3.30.1490.10 75 132 9.9E-26 T 01-11-2018 MLA2C4_00745 3a58915a4d26a51e2837a10f56cbee63 132 SUPERFAMILY SSF56047 2 132 3.27E-49 T 01-11-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00745 3a58915a4d26a51e2837a10f56cbee63 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.966 T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00745 3a58915a4d26a51e2837a10f56cbee63 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00745 3a58915a4d26a51e2837a10f56cbee63 132 Pfam PF00410 Ribosomal protein S8 5 132 3.9E-54 T 01-11-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 01-11-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 Gene3D G3DSA:2.30.140.10 1 52 1.2E-24 T 01-11-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 SUPERFAMILY SSF53335 3 274 1.83E-88 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 42.126 T 01-11-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 Gene3D G3DSA:3.40.50.150 53 274 1.8E-77 T 01-11-2018 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 3.6E-120 T 01-11-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 Pfam PF01564 Spermine/spermidine synthase domain 58 236 5.1E-68 T 01-11-2018 MLA2C4_27800 d1c1af3f3fe1f21aef1c70053d144582 275 Pfam PF17284 Spermidine synthase tetramerisation domain 3 55 7.2E-20 T 01-11-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_16375 30bafecede741fde3de5eb03ef509298 375 SUPERFAMILY SSF58100 33 369 1.36E-102 T 01-11-2018 MLA2C4_16375 30bafecede741fde3de5eb03ef509298 375 Gene3D G3DSA:1.20.1170.10 39 375 7.4E-132 T 01-11-2018 MLA2C4_16375 30bafecede741fde3de5eb03ef509298 375 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 46 223 1.5E-59 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_20160 27b590500fc863f27e79ec28caedbc1d 62 Gene3D G3DSA:2.30.170.40 19 62 6.8E-18 T 01-11-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20160 27b590500fc863f27e79ec28caedbc1d 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.58 T 01-11-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20160 27b590500fc863f27e79ec28caedbc1d 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 6.8E-23 T 01-11-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20160 27b590500fc863f27e79ec28caedbc1d 62 Pfam PF00830 Ribosomal L28 family 3 58 2.0E-20 T 01-11-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20160 27b590500fc863f27e79ec28caedbc1d 62 SUPERFAMILY SSF143800 1 60 3.73E-23 T 01-11-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 Gene3D G3DSA:3.40.50.300 285 514 3.7E-42 T 01-11-2018 MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 SUPERFAMILY SSF52540 4 242 7.5E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 Pfam PF00005 ABC transporter 338 466 5.1E-21 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 Pfam PF12848 ABC transporter 228 309 3.5E-22 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 Gene3D G3DSA:3.40.50.300 4 281 1.0E-62 T 01-11-2018 MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 SUPERFAMILY SSF52540 303 512 2.13E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 SMART SM00382 345 511 7.8E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 SMART SM00382 28 233 1.8E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26435 71bf52b34e71c6a466298e7419210d59 515 Pfam PF00005 ABC transporter 20 188 2.0E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_08055 f389e79249984082cc93aa592b96c5a1 113 PIRSF PIRSF029904 1 111 1.1E-56 T 01-11-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD MLA2C4_08055 f389e79249984082cc93aa592b96c5a1 113 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 4.8E-20 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MLA2C4_08055 f389e79249984082cc93aa592b96c5a1 113 SUPERFAMILY SSF101386 4 104 1.96E-28 T 01-11-2018 MLA2C4_08055 f389e79249984082cc93aa592b96c5a1 113 Gene3D G3DSA:1.10.287.1080 2 113 3.1E-35 T 01-11-2018 MLA2C4_24120 f8d6d08d21dde659f12e0dca32ad0b1e 267 Hamap MF_00361 NAD kinase [nadK]. 5 264 20.248 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MLA2C4_24120 f8d6d08d21dde659f12e0dca32ad0b1e 267 Gene3D G3DSA:2.60.200.30 109 245 1.1E-71 T 01-11-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MLA2C4_24120 f8d6d08d21dde659f12e0dca32ad0b1e 267 Gene3D G3DSA:3.40.50.10330 39 267 1.1E-71 T 01-11-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MLA2C4_24120 f8d6d08d21dde659f12e0dca32ad0b1e 267 Pfam PF01513 ATP-NAD kinase 39 252 1.8E-16 T 01-11-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MLA2C4_24120 f8d6d08d21dde659f12e0dca32ad0b1e 267 SUPERFAMILY SSF111331 6 266 3.6E-56 T 01-11-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MLA2C4_25570 d7ad4162cad89e8f1c4e04a1a2538fd5 237 SUPERFAMILY SSF48371 12 222 6.28E-58 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_25570 d7ad4162cad89e8f1c4e04a1a2538fd5 237 Gene3D G3DSA:1.25.10.90 1 237 1.1E-104 T 01-11-2018 MLA2C4_25570 d7ad4162cad89e8f1c4e04a1a2538fd5 237 Pfam PF08713 DNA alkylation repair enzyme 8 221 4.8E-71 T 01-11-2018 IPR014825 DNA alkylation repair enzyme MLA2C4_15610 dfcb0d5a83db7f484f5690651fd8a89a 253 SUPERFAMILY SSF53448 16 197 1.69E-33 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_15610 dfcb0d5a83db7f484f5690651fd8a89a 253 Pfam PF00535 Glycosyl transferase family 2 19 123 3.1E-20 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_15610 dfcb0d5a83db7f484f5690651fd8a89a 253 Gene3D G3DSA:3.90.550.10 2 212 2.7E-33 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_15610 dfcb0d5a83db7f484f5690651fd8a89a 253 Pfam PF02709 N-terminal domain of galactosyltransferase 153 195 1.5E-5 T 01-11-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 MLA2C4_12725 5382188c01058986c6f1961577fa0ea5 194 Gene3D G3DSA:3.40.50.150 4 194 1.9E-45 T 01-11-2018 MLA2C4_12725 5382188c01058986c6f1961577fa0ea5 194 Pfam PF01596 O-methyltransferase 27 183 2.4E-23 T 01-11-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MLA2C4_12725 5382188c01058986c6f1961577fa0ea5 194 SUPERFAMILY SSF53335 24 193 3.8E-31 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_09990 b3ec6181ed835f2c4ec07cc4f7223fd6 276 SUPERFAMILY SSF88713 40 269 2.45E-66 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_09990 b3ec6181ed835f2c4ec07cc4f7223fd6 276 Pfam PF01522 Polysaccharide deacetylase 80 197 1.5E-33 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_09990 b3ec6181ed835f2c4ec07cc4f7223fd6 276 Gene3D G3DSA:3.20.20.370 62 276 3.9E-90 T 01-11-2018 MLA2C4_11805 14cea3f6927fe879c0521a67a8df0ebd 330 Gene3D G3DSA:3.90.1690.10 152 319 8.3E-7 T 01-11-2018 MLA2C4_11805 14cea3f6927fe879c0521a67a8df0ebd 330 Pfam PF03864 Phage major capsid protein E 9 317 2.2E-19 T 01-11-2018 IPR005564 Major capsid protein GpE MLA2C4_08480 73359f01adb63b05e72e19e30e14d0b3 149 SUPERFAMILY SSF46785 1 90 3.39E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08480 73359f01adb63b05e72e19e30e14d0b3 149 Pfam PF12840 Helix-turn-helix domain 14 67 1.1E-9 T 01-11-2018 MLA2C4_08480 73359f01adb63b05e72e19e30e14d0b3 149 SMART SM00418 13 91 0.0093 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_08480 73359f01adb63b05e72e19e30e14d0b3 149 Gene3D G3DSA:1.10.10.10 3 84 8.6E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_02065 f9f80766971d2ddc629b4d604030b4b0 305 Gene3D G3DSA:3.40.50.1980 137 305 3.2E-58 T 01-11-2018 MLA2C4_02065 f9f80766971d2ddc629b4d604030b4b0 305 Pfam PF01497 Periplasmic binding protein 72 278 1.4E-29 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_02065 f9f80766971d2ddc629b4d604030b4b0 305 Gene3D G3DSA:3.40.50.1980 48 136 1.0E-24 T 01-11-2018 MLA2C4_02065 f9f80766971d2ddc629b4d604030b4b0 305 SUPERFAMILY SSF53807 39 298 2.51E-52 T 01-11-2018 MLA2C4_07010 317595c1cb5aab51fa790635403da21e 111 Pfam PF13045 Protein of unknown function (DUF3905) 9 91 7.6E-47 T 01-11-2018 IPR024999 Protein of unknown function DUF3905 MLA2C4_11170 db31ce28a91878e935dd539c76f516f6 309 SUPERFAMILY SSF56112 9 259 2.77E-37 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_11170 db31ce28a91878e935dd539c76f516f6 309 Gene3D G3DSA:3.90.1200.10 99 287 2.8E-24 T 01-11-2018 MLA2C4_11170 db31ce28a91878e935dd539c76f516f6 309 Pfam PF01636 Phosphotransferase enzyme family 20 240 6.2E-24 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_14885 f1a0f2201e4d6b6562aa3674c0f95879 247 Gene3D G3DSA:3.40.50.150 22 236 4.1E-21 T 01-11-2018 MLA2C4_14885 f1a0f2201e4d6b6562aa3674c0f95879 247 Pfam PF13489 Methyltransferase domain 40 211 9.7E-13 T 01-11-2018 MLA2C4_14885 f1a0f2201e4d6b6562aa3674c0f95879 247 SUPERFAMILY SSF53335 17 229 7.67E-26 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 Pfam PF02445 Quinolinate synthetase A protein 29 366 7.5E-107 T 01-11-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 Gene3D G3DSA:3.40.50.10800 112 366 5.5E-82 T 01-11-2018 MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 Gene3D G3DSA:3.40.50.10800 29 348 5.5E-82 T 01-11-2018 MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 Gene3D G3DSA:3.40.50.10800 230 315 5.5E-82 T 01-11-2018 MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 21 366 5.3E-116 T 01-11-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 SUPERFAMILY SSF142754 34 366 6.41E-98 T 01-11-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MLA2C4_23090 0ee8be78a2fca89b50549fe3220061dd 368 Hamap MF_00569 Quinolinate synthase A [nadA]. 22 367 56.864 T 01-11-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MLA2C4_10080 16dca8cee7ea101d6dc4d9a44290d2e6 612 Gene3D G3DSA:1.10.510.40 380 599 2.0E-55 T 01-11-2018 MLA2C4_10080 16dca8cee7ea101d6dc4d9a44290d2e6 612 Pfam PF06276 Ferric iron reductase FhuF-like transporter 411 581 4.3E-31 T 01-11-2018 IPR022770 Ferric iron reductase FhuF domain MLA2C4_10080 16dca8cee7ea101d6dc4d9a44290d2e6 612 Gene3D G3DSA:1.10.274.90 3 138 1.0E-5 T 01-11-2018 MLA2C4_10080 16dca8cee7ea101d6dc4d9a44290d2e6 612 Pfam PF04183 IucA / IucC family 149 390 5.7E-74 T 01-11-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 MLA2C4_27245 0c20ae5580c9dcbd29cab9e750ba232f 355 Gene3D G3DSA:3.40.50.2000 222 337 1.5E-9 T 01-11-2018 MLA2C4_27245 0c20ae5580c9dcbd29cab9e750ba232f 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 245 322 3.8E-5 T 01-11-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MLA2C4_27245 0c20ae5580c9dcbd29cab9e750ba232f 355 SUPERFAMILY SSF53756 5 293 6.91E-11 T 01-11-2018 MLA2C4_00420 7f842916e45203f5abaa9a4fa665c646 67 SUPERFAMILY SSF47413 4 65 1.02E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_00420 7f842916e45203f5abaa9a4fa665c646 67 SMART SM00530 9 64 3.6E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_00420 7f842916e45203f5abaa9a4fa665c646 67 Gene3D G3DSA:1.10.260.40 2 67 5.9E-19 T 01-11-2018 MLA2C4_00420 7f842916e45203f5abaa9a4fa665c646 67 Pfam PF01381 Helix-turn-helix 10 64 1.6E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 Gene3D G3DSA:3.40.800.20 2 348 4.9E-101 T 01-11-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 6.5E-17 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 6.5E-17 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 6.5E-17 T 01-11-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 Pfam PF00850 Histone deacetylase domain 20 314 4.9E-77 T 01-11-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 349 368 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 272 288 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 311 330 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 14 34 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 332 348 1.5E-42 T 01-11-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 MLA2C4_24240 ba42bd2b951814bbe6e2562b65b264c2 388 SUPERFAMILY SSF52768 3 365 1.44E-106 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily MLA2C4_20625 8421a9000617f606dbe993251f966a6b 393 Pfam PF01098 Cell cycle protein 13 369 4.5E-107 T 01-11-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20625 8421a9000617f606dbe993251f966a6b 393 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 326 350 - T 01-11-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20625 8421a9000617f606dbe993251f966a6b 393 PRINTS PR00173 Glutamate-aspartate symporter signature 40 65 8.7E-5 T 01-11-2018 MLA2C4_20625 8421a9000617f606dbe993251f966a6b 393 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 8.7E-5 T 01-11-2018 MLA2C4_20625 8421a9000617f606dbe993251f966a6b 393 PRINTS PR00173 Glutamate-aspartate symporter signature 156 175 8.7E-5 T 01-11-2018 MLA2C4_20625 8421a9000617f606dbe993251f966a6b 393 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 8.7E-5 T 01-11-2018 MLA2C4_25545 aa0f59fc4855649553f7093bb0967d9f 179 Gene3D G3DSA:2.60.40.200 24 175 2.9E-48 T 01-11-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MLA2C4_25545 aa0f59fc4855649553f7093bb0967d9f 179 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 34 169 1.0E-36 T 01-11-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MLA2C4_25545 aa0f59fc4855649553f7093bb0967d9f 179 SUPERFAMILY SSF49329 30 169 4.32E-39 T 01-11-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MLA2C4_12010 39a077dfcd0b9a9f908771cb302fec0d 178 Gene3D G3DSA:2.60.120.40 35 173 2.5E-11 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_12010 39a077dfcd0b9a9f908771cb302fec0d 178 SUPERFAMILY SSF49842 38 170 4.97E-20 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_12010 39a077dfcd0b9a9f908771cb302fec0d 178 Pfam PF00386 C1q domain 39 160 5.5E-6 T 01-11-2018 IPR001073 C1q domain MLA2C4_04080 f9dc0b659889f84a06bc1fd7c094bcf8 139 Pfam PF02600 Disulfide bond formation protein DsbB 10 111 1.8E-11 T 01-11-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 MLA2C4_04080 f9dc0b659889f84a06bc1fd7c094bcf8 139 PIRSF PIRSF036659 1 139 1.8E-59 T 01-11-2018 IPR012187 Disulphide bond formation protein BdbC MLA2C4_04080 f9dc0b659889f84a06bc1fd7c094bcf8 139 Gene3D G3DSA:1.20.1550.10 3 114 1.3E-11 T 01-11-2018 IPR023380 DsbB-like superfamily MLA2C4_04080 f9dc0b659889f84a06bc1fd7c094bcf8 139 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 4 139 24.638 T 01-11-2018 IPR012187 Disulphide bond formation protein BdbC MLA2C4_04080 f9dc0b659889f84a06bc1fd7c094bcf8 139 SUPERFAMILY SSF158442 12 135 2.48E-29 T 01-11-2018 IPR023380 DsbB-like superfamily MLA2C4_03530 685de4d4fc4034bd84c1b623d7bdbbb6 308 Gene3D G3DSA:3.40.50.2300 139 273 5.2E-93 T 01-11-2018 MLA2C4_03530 685de4d4fc4034bd84c1b623d7bdbbb6 308 Gene3D G3DSA:3.40.50.2300 44 292 5.2E-93 T 01-11-2018 MLA2C4_03530 685de4d4fc4034bd84c1b623d7bdbbb6 308 Pfam PF13407 Periplasmic binding protein domain 41 292 3.4E-67 T 01-11-2018 IPR025997 Periplasmic binding protein MLA2C4_03530 685de4d4fc4034bd84c1b623d7bdbbb6 308 SUPERFAMILY SSF53822 33 307 5.41E-92 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 SUPERFAMILY SSF52374 5 328 4.29E-81 T 01-11-2018 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 Pfam PF00579 tRNA synthetases class I (W and Y) 5 281 2.8E-55 T 01-11-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 328 4.4E-83 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 Gene3D G3DSA:1.10.240.10 196 296 4.5E-110 T 01-11-2018 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 Gene3D G3DSA:3.40.50.620 6 327 4.5E-110 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 6.4E-12 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 6.4E-12 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_17565 23cb31674d55481b03b492cea16536af 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 6.4E-12 T 01-11-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MLA2C4_11845 d66a8ee70bd43f81cc555b34e38123e9 152 Gene3D G3DSA:3.30.2220.30 19 138 3.6E-8 T 01-11-2018 IPR038559 Clostridium phage phiCD119, XkdN superfamily MLA2C4_11845 d66a8ee70bd43f81cc555b34e38123e9 152 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 15 151 2.6E-17 T 01-11-2018 IPR014986 Clostridium phage phiCD119, XkdN MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 01-11-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 215 2.3E-38 T 01-11-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 212 2.2E-38 T 01-11-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 SUPERFAMILY SSF53681 1 112 1.1E-26 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 Gene3D G3DSA:3.40.50.1860 2 210 9.2E-51 T 01-11-2018 MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 Gene3D G3DSA:3.40.50.1860 105 204 9.2E-51 T 01-11-2018 MLA2C4_24720 415545f6bcf7bdcdaf5ab015c46cb4d3 225 SUPERFAMILY SSF53681 116 216 2.45E-18 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_14395 78ca26c97404936d805eb9fa1c6e5692 149 Pfam PF00293 NUDIX domain 26 131 1.1E-10 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_14395 78ca26c97404936d805eb9fa1c6e5692 149 Gene3D G3DSA:3.90.79.10 1 148 9.2E-34 T 01-11-2018 MLA2C4_14395 78ca26c97404936d805eb9fa1c6e5692 149 SUPERFAMILY SSF55811 3 146 2.17E-18 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_19650 59207d34a0380723e6b23f8a4aec5b77 328 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 59 194 3.4E-15 T 01-11-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MLA2C4_19650 59207d34a0380723e6b23f8a4aec5b77 328 SMART SM00148 50 194 2.2E-59 T 01-11-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MLA2C4_19650 59207d34a0380723e6b23f8a4aec5b77 328 Gene3D G3DSA:3.20.20.190 32 328 4.6E-122 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_19650 59207d34a0380723e6b23f8a4aec5b77 328 SUPERFAMILY SSF51695 33 324 2.72E-63 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 Gene3D G3DSA:3.40.50.1860 4 222 1.8E-86 T 01-11-2018 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 Gene3D G3DSA:3.40.50.1860 104 214 1.8E-86 T 01-11-2018 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 SUPERFAMILY SSF53681 1 114 7.19E-37 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 9.1E-75 T 01-11-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 01-11-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 SUPERFAMILY SSF53681 118 228 1.05E-33 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 6.4E-61 T 01-11-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_11120 55e92683f38ba26812f3a649b03aa84b 232 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 192 202 - T 01-11-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_08520 b3b1d530275c4e3882c69f200fba8ad3 225 SUPERFAMILY SSF103088 107 223 7.06E-31 T 01-11-2018 IPR036737 OmpA-like domain superfamily MLA2C4_08520 b3b1d530275c4e3882c69f200fba8ad3 225 Gene3D G3DSA:3.30.1330.60 75 224 1.1E-42 T 01-11-2018 IPR036737 OmpA-like domain superfamily MLA2C4_08520 b3b1d530275c4e3882c69f200fba8ad3 225 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 6 50 7.6E-13 T 01-11-2018 IPR025713 Motility protein B, N-terminal domain MLA2C4_08520 b3b1d530275c4e3882c69f200fba8ad3 225 Pfam PF00691 OmpA family 119 217 7.3E-18 T 01-11-2018 IPR006665 OmpA-like domain MLA2C4_23740 a0f08bb61ad225de16216b4d17979866 217 Gene3D G3DSA:2.40.30.170 105 217 8.5E-35 T 01-11-2018 MLA2C4_23740 a0f08bb61ad225de16216b4d17979866 217 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 205 217 4.2E-5 T 01-11-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MLA2C4_23740 a0f08bb61ad225de16216b4d17979866 217 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 134 158 4.2E-5 T 01-11-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MLA2C4_23740 a0f08bb61ad225de16216b4d17979866 217 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 86 165 2.3E-13 T 01-11-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 Pfam PF01546 Peptidase family M20/M25/M40 72 384 4.5E-32 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 375 9.4E-119 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 Gene3D G3DSA:3.30.70.360 181 295 5.0E-141 T 01-11-2018 MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 Pfam PF07687 Peptidase dimerisation domain 186 283 1.4E-15 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 PIRSF PIRSF005962 2 391 3.1E-136 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 SUPERFAMILY SSF53187 11 388 3.43E-82 T 01-11-2018 MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 Gene3D G3DSA:3.40.630.10 14 372 5.0E-141 T 01-11-2018 MLA2C4_03715 c4880621e799a98a99a42f0c64de7b35 391 SUPERFAMILY SSF55031 184 295 3.27E-31 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 SUPERFAMILY SSF52540 3 159 1.39E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 Gene3D G3DSA:3.40.50.300 1 165 5.1E-52 T 01-11-2018 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 PRINTS PR01100 Shikimate kinase family signature 4 19 1.5E-21 T 01-11-2018 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 PRINTS PR01100 Shikimate kinase family signature 28 41 1.5E-21 T 01-11-2018 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 PRINTS PR01100 Shikimate kinase family signature 94 111 1.5E-21 T 01-11-2018 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 PRINTS PR01100 Shikimate kinase family signature 56 64 1.5E-21 T 01-11-2018 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 PRINTS PR01100 Shikimate kinase family signature 73 82 1.5E-21 T 01-11-2018 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 Hamap MF_00109 Shikimate kinase [aroK]. 1 164 25.792 T 01-11-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MLA2C4_22150 3bf0e08ffb8454301a40aaf173b90189 165 Pfam PF01202 Shikimate kinase 10 163 1.4E-48 T 01-11-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MLA2C4_09610 f26821bef4b280081ec0a8d91db1bb30 208 PIRSF PIRSF006324 1 208 6.7E-59 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_09610 f26821bef4b280081ec0a8d91db1bb30 208 Pfam PF01810 LysE type translocator 14 206 1.1E-38 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_19855 25b83d225677097805ebfa5d1f483cd0 249 SUPERFAMILY SSF52096 44 230 2.57E-36 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_19855 25b83d225677097805ebfa5d1f483cd0 249 Pfam PF00574 Clp protease 46 222 5.2E-34 T 01-11-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MLA2C4_19855 25b83d225677097805ebfa5d1f483cd0 249 Gene3D G3DSA:3.90.226.10 46 223 2.0E-29 T 01-11-2018 MLA2C4_13290 b61dc7ee6f719ea3fa132f0632f99b76 326 Pfam PF06013 Proteins of 100 residues with WXG 3 87 1.1E-14 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_13290 b61dc7ee6f719ea3fa132f0632f99b76 326 Gene3D G3DSA:1.10.287.850 1 94 2.4E-28 T 01-11-2018 MLA2C4_13290 b61dc7ee6f719ea3fa132f0632f99b76 326 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 3.1E-17 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_13290 b61dc7ee6f719ea3fa132f0632f99b76 326 SUPERFAMILY SSF140453 3 93 2.88E-11 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_26670 3e162f3621902e7f561b36351ae7a61c 152 Gene3D G3DSA:3.90.79.10 1 152 1.7E-41 T 01-11-2018 MLA2C4_26670 3e162f3621902e7f561b36351ae7a61c 152 PRINTS PR00502 NUDIX hydrolase family signature 26 40 9.1E-6 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_26670 3e162f3621902e7f561b36351ae7a61c 152 PRINTS PR00502 NUDIX hydrolase family signature 40 55 9.1E-6 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_26670 3e162f3621902e7f561b36351ae7a61c 152 Pfam PF00293 NUDIX domain 4 124 1.5E-16 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_26670 3e162f3621902e7f561b36351ae7a61c 152 SUPERFAMILY SSF55811 3 128 3.01E-29 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 SUPERFAMILY SSF48019 214 333 1.63E-26 T 01-11-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 333 6.9E-101 T 01-11-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 Gene3D G3DSA:1.20.272.10 211 335 1.9E-40 T 01-11-2018 MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 Gene3D G3DSA:3.40.50.300 1 140 2.9E-40 T 01-11-2018 MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 Gene3D G3DSA:1.10.8.60 141 210 5.4E-11 T 01-11-2018 MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 SUPERFAMILY SSF52540 9 210 1.1E-28 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22575 ae464933e365b4013d52a80785ebf17e 336 Pfam PF06144 DNA polymerase III, delta subunit 17 191 4.4E-47 T 01-11-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MLA2C4_25285 4acb343de858433849473713026f077e 243 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 87 114 2.3E-10 T 01-11-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MLA2C4_25285 4acb343de858433849473713026f077e 243 SUPERFAMILY SSF57716 89 117 4.99E-6 T 01-11-2018 MLA2C4_25285 4acb343de858433849473713026f077e 243 SUPERFAMILY SSF109635 2 88 2.22E-15 T 01-11-2018 IPR037187 DksA, N-terminal domain superfamily MLA2C4_25285 4acb343de858433849473713026f077e 243 Gene3D G3DSA:1.20.120.910 1 126 1.2E-34 T 01-11-2018 MLA2C4_25285 4acb343de858433849473713026f077e 243 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 160 8.9E-67 T 01-11-2018 IPR014240 Regulatory protein, YteA family MLA2C4_05140 b0f804d0b90f0e3c04003423b8cfb874 103 Gene3D G3DSA:1.10.10.10 2 103 9.9E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05140 b0f804d0b90f0e3c04003423b8cfb874 103 SUPERFAMILY SSF46785 5 101 6.98E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05140 b0f804d0b90f0e3c04003423b8cfb874 103 SMART SM00418 5 101 2.2E-4 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 Gene3D G3DSA:3.90.105.10 420 477 2.0E-18 T 01-11-2018 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 369 3.9E-113 T 01-11-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 403 460 8.9E-10 T 01-11-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 SUPERFAMILY SSF55904 342 485 1.7E-38 T 01-11-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 SUPERFAMILY SSF53383 6 385 2.02E-96 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 01-11-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 Gene3D G3DSA:3.90.1150.10 310 406 3.4E-6 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_20695 6fa5e6ec98f5bcb617ad1651143300e1 490 Gene3D G3DSA:3.40.640.10 6 282 3.8E-94 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_22340 05abd8173a5dd25fa67f54feaa47b6f8 425 SUPERFAMILY SSF103473 13 340 6.67E-28 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_22340 05abd8173a5dd25fa67f54feaa47b6f8 425 Pfam PF07690 Major Facilitator Superfamily 20 337 1.4E-19 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_22340 05abd8173a5dd25fa67f54feaa47b6f8 425 Gene3D G3DSA:1.20.1250.20 10 341 8.5E-26 T 01-11-2018 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 Pfam PF01345 Domain of unknown function DUF11 279 374 7.7E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 Pfam PF01345 Domain of unknown function DUF11 146 240 1.1E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 Pfam PF01345 Domain of unknown function DUF11 29 103 1.8E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 146 198 1.1E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 29 66 5.5E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 279 331 1.3E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 SUPERFAMILY SSF49401 280 378 2.34E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_19030 9b09de0b2e241972ceddac8a7b5cb1a1 429 Gene3D G3DSA:2.60.40.740 272 404 1.6E-6 T 01-11-2018 MLA2C4_19500 0032c4c90a3de80fdece20b25ec1a897 272 Pfam PF00756 Putative esterase 26 254 1.8E-22 T 01-11-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MLA2C4_19500 0032c4c90a3de80fdece20b25ec1a897 272 Gene3D G3DSA:3.40.50.1820 14 272 1.6E-85 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_19500 0032c4c90a3de80fdece20b25ec1a897 272 SUPERFAMILY SSF53474 5 269 1.61E-61 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_01300 7d16825c26645a90ae0ad499ddf94190 318 Gene3D G3DSA:1.10.3720.10 82 311 1.6E-21 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01300 7d16825c26645a90ae0ad499ddf94190 318 SUPERFAMILY SSF161098 89 299 5.36E-17 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01300 7d16825c26645a90ae0ad499ddf94190 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 316 2.5E-40 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 300 310 - T 01-11-2018 IPR022398 Peptidase S8, subtilisin, His-active site MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Pfam PF02225 PA domain 460 540 2.7E-17 T 01-11-2018 IPR003137 PA domain MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 224 235 - T 01-11-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Pfam PF00082 Subtilase family 219 668 4.8E-66 T 01-11-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 PIRSF PIRSF037844 1 1413 0.0 T 01-11-2018 IPR017292 Peptidase S8A, Vpr MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 SUPERFAMILY SSF49384 1078 1188 5.23E-8 T 01-11-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Gene3D G3DSA:3.40.50.200 552 696 1.4E-26 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Pfam PF00963 Cohesin domain 1078 1143 1.1E-4 T 01-11-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 SUPERFAMILY SSF52743 204 678 3.27E-85 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 296 309 4.1E-21 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 617 633 4.1E-21 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 219 238 4.1E-21 T 01-11-2018 IPR015500 Peptidase S8, subtilisin-related MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Gene3D G3DSA:2.60.40.680 1072 1207 7.3E-6 T 01-11-2018 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 SUPERFAMILY SSF52025 458 530 1.7E-19 T 01-11-2018 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 SUPERFAMILY SSF63446 1326 1381 9.03E-8 T 01-11-2018 IPR036439 Dockerin domain superfamily GO:0000272 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Gene3D G3DSA:3.40.50.200 192 441 5.3E-54 T 01-11-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Gene3D G3DSA:2.60.40.1120 1220 1327 1.3E-5 T 01-11-2018 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Gene3D G3DSA:3.50.30.30 443 551 2.2E-33 T 01-11-2018 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Gene3D G3DSA:1.10.1330.10 1328 1385 6.5E-9 T 01-11-2018 MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 618 628 - T 01-11-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MLA2C4_03355 52464c518cc22ca46eb115812015e2e2 1413 Pfam PF05922 Peptidase inhibitor I9 84 185 9.0E-10 T 01-11-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MLA2C4_16150 5f6c174b78b311e1c15960f5c3f68cbb 242 Gene3D G3DSA:3.30.1600.10 31 165 1.3E-71 T 01-11-2018 IPR026591 Sirtuin, catalytic core small domain superfamily MLA2C4_16150 5f6c174b78b311e1c15960f5c3f68cbb 242 SUPERFAMILY SSF52467 3 238 6.07E-76 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_16150 5f6c174b78b311e1c15960f5c3f68cbb 242 Pfam PF02146 Sir2 family 22 193 3.7E-51 T 01-11-2018 IPR003000 Sirtuin family GO:0070403 MLA2C4_16150 5f6c174b78b311e1c15960f5c3f68cbb 242 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 6 239 62.474 T 01-11-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 MLA2C4_16150 5f6c174b78b311e1c15960f5c3f68cbb 242 Gene3D G3DSA:3.40.50.1220 13 236 1.3E-71 T 01-11-2018 MLA2C4_24780 88b911289a02a4a24fb32e6c9001215f 177 SMART SM00014 61 169 4.8E-13 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_24780 88b911289a02a4a24fb32e6c9001215f 177 SUPERFAMILY SSF48317 9 174 3.01E-39 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_24780 88b911289a02a4a24fb32e6c9001215f 177 Gene3D G3DSA:1.20.144.10 11 97 1.2E-6 T 01-11-2018 MLA2C4_24780 88b911289a02a4a24fb32e6c9001215f 177 Gene3D G3DSA:1.20.144.10 98 177 8.9E-17 T 01-11-2018 MLA2C4_24780 88b911289a02a4a24fb32e6c9001215f 177 Pfam PF01569 PAP2 superfamily 62 172 7.2E-22 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_19520 c3b16f8bf71db575dae9924944cb0c26 321 Gene3D G3DSA:3.40.50.1980 43 167 1.8E-31 T 01-11-2018 MLA2C4_19520 c3b16f8bf71db575dae9924944cb0c26 321 Pfam PF01497 Periplasmic binding protein 64 292 1.4E-34 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_19520 c3b16f8bf71db575dae9924944cb0c26 321 Gene3D G3DSA:3.40.50.1980 168 321 1.5E-41 T 01-11-2018 MLA2C4_19520 c3b16f8bf71db575dae9924944cb0c26 321 SUPERFAMILY SSF53807 50 314 9.03E-59 T 01-11-2018 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Hamap MF_01252 Flavohemoprotein [hmp]. 1 401 58.558 T 01-11-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Pfam PF00042 Globin 7 103 3.3E-10 T 01-11-2018 IPR000971 Globin GO:0020037 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Pfam PF00175 Oxidoreductase NAD-binding domain 269 376 2.3E-17 T 01-11-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Gene3D G3DSA:3.40.50.80 259 401 2.7E-34 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 SUPERFAMILY SSF52343 262 397 5.89E-37 T 01-11-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Gene3D G3DSA:2.40.30.10 149 258 2.4E-38 T 01-11-2018 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 SUPERFAMILY SSF63380 149 259 5.11E-31 T 01-11-2018 IPR017938 Riboflavin synthase-like beta-barrel MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Pfam PF00970 Oxidoreductase FAD-binding domain 156 257 5.6E-10 T 01-11-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 Gene3D G3DSA:1.10.490.10 1 143 1.8E-55 T 01-11-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 SUPERFAMILY SSF46458 2 141 3.49E-41 T 01-11-2018 IPR009050 Globin-like superfamily MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 363 371 1.5E-9 T 01-11-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 268 287 1.5E-9 T 01-11-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MLA2C4_07645 486cf3041ccc4a78d007d90ac55eb40a 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 1.5E-9 T 01-11-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 Gene3D G3DSA:2.40.290.10 2 180 2.1E-16 T 01-11-2018 IPR016194 SPOC-like, C-terminal domain superfamily MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 SMART SM00559 53 182 2.3E-23 T 01-11-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 255 29.173 T 01-11-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 258 6.3E-75 T 01-11-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 PIRSF PIRSF006493 1 270 8.0E-78 T 01-11-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 193 1.2E-31 T 01-11-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 MLA2C4_04440 e9947743d742ff9b6ea311ab4c05794b 270 SUPERFAMILY SSF100939 2 260 1.84E-39 T 01-11-2018 IPR016194 SPOC-like, C-terminal domain superfamily MLA2C4_06445 db83c8f896fecb22033135f0bfbc969c 243 Gene3D G3DSA:3.40.50.1820 1 241 2.9E-49 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_06445 db83c8f896fecb22033135f0bfbc969c 243 Pfam PF00756 Putative esterase 15 238 2.6E-49 T 01-11-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MLA2C4_06445 db83c8f896fecb22033135f0bfbc969c 243 SUPERFAMILY SSF53474 4 239 1.19E-36 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_22090 5baec6cf125f5bfaf71ea1873ae6150d 124 SMART SM00345 17 76 4.1E-14 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_22090 5baec6cf125f5bfaf71ea1873ae6150d 124 Gene3D G3DSA:1.10.10.10 10 124 7.6E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22090 5baec6cf125f5bfaf71ea1873ae6150d 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 4.9E-15 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_22090 5baec6cf125f5bfaf71ea1873ae6150d 124 SUPERFAMILY SSF46785 6 80 1.13E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 SUPERFAMILY SSF53448 8 162 1.13E-24 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 Gene3D G3DSA:1.25.40.10 266 365 5.8E-15 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 Pfam PF13176 Tetratricopeptide repeat 235 263 0.034 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 Gene3D G3DSA:3.90.550.10 2 168 9.8E-25 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 Gene3D G3DSA:1.25.40.10 186 264 3.3E-7 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 SUPERFAMILY SSF48452 196 347 1.44E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_06355 80f14b96cd05d2c504701a701612a7ab 366 Pfam PF00535 Glycosyl transferase family 2 10 147 7.3E-18 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_03240 c87234b501d8b8a6e789751e24b255a4 321 Pfam PF01497 Periplasmic binding protein 61 295 2.2E-36 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_03240 c87234b501d8b8a6e789751e24b255a4 321 Gene3D G3DSA:3.40.50.1980 148 321 6.9E-73 T 01-11-2018 MLA2C4_03240 c87234b501d8b8a6e789751e24b255a4 321 Gene3D G3DSA:3.40.50.1980 41 147 1.7E-38 T 01-11-2018 MLA2C4_03240 c87234b501d8b8a6e789751e24b255a4 321 SUPERFAMILY SSF53807 43 315 5.69E-72 T 01-11-2018 MLA2C4_23745 35f46f404ede0d1591ab90ae70ce8e51 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 2.4E-10 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23745 35f46f404ede0d1591ab90ae70ce8e51 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.3E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23745 35f46f404ede0d1591ab90ae70ce8e51 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.3E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_23745 35f46f404ede0d1591ab90ae70ce8e51 205 SUPERFAMILY SSF46689 9 76 9.98E-18 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_23745 35f46f404ede0d1591ab90ae70ce8e51 205 Pfam PF14278 Transcriptional regulator C-terminal region 95 173 4.3E-15 T 01-11-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type MLA2C4_23745 35f46f404ede0d1591ab90ae70ce8e51 205 Gene3D G3DSA:1.10.357.10 6 197 9.0E-47 T 01-11-2018 MLA2C4_22155 3e1c1af165fd86368d556a9567f42886 216 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 114 211 1.2E-17 T 01-11-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MLA2C4_22155 3e1c1af165fd86368d556a9567f42886 216 Gene3D G3DSA:2.60.120.620 20 212 6.7E-68 T 01-11-2018 MLA2C4_22155 3e1c1af165fd86368d556a9567f42886 216 SMART SM00702 39 211 9.8E-43 T 01-11-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 Pfam PF07690 Major Facilitator Superfamily 23 270 2.8E-34 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 89 113 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 355 378 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 146 168 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 263 283 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 28 44 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 58 77 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 116 137 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 PRINTS PR01035 Tetracycline resistance protein signature 174 194 3.0E-39 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 SUPERFAMILY SSF103473 15 402 2.88E-61 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_12790 3c4b236aa8935c3f46cd6bc9e557075b 409 Gene3D G3DSA:1.20.1250.20 12 403 4.6E-65 T 01-11-2018 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 182 2.6E-45 T 01-11-2018 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 3 182 4.5E-18 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 Gene3D G3DSA:3.40.50.1000 2 200 2.4E-53 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 SUPERFAMILY SSF56784 1 213 5.29E-52 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 2.7E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 142 2.7E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.7E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 164 2.7E-10 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 Gene3D G3DSA:1.10.150.240 14 82 2.4E-53 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_21985 20c32431ab427c6322e5073b99aec769 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 174 1.1E-5 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_10805 ee6650fe5cbb3782b6d86a5cdb8ef665 320 Gene3D G3DSA:3.40.50.300 22 188 1.3E-45 T 01-11-2018 MLA2C4_10805 ee6650fe5cbb3782b6d86a5cdb8ef665 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 3.5E-64 T 01-11-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MLA2C4_10805 ee6650fe5cbb3782b6d86a5cdb8ef665 320 SUPERFAMILY SSF52540 9 285 2.89E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10805 ee6650fe5cbb3782b6d86a5cdb8ef665 320 PIRSF PIRSF002849 1 315 1.2E-135 T 01-11-2018 MLA2C4_10805 ee6650fe5cbb3782b6d86a5cdb8ef665 320 Gene3D G3DSA:1.10.8.300 202 310 2.0E-37 T 01-11-2018 MLA2C4_20915 3bae415a712fbbcf4332d9a30a327e14 513 Gene3D G3DSA:1.20.1720.10 17 223 1.6E-53 T 01-11-2018 MLA2C4_20915 3bae415a712fbbcf4332d9a30a327e14 513 Pfam PF07690 Major Facilitator Superfamily 20 411 6.2E-52 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_20915 3bae415a712fbbcf4332d9a30a327e14 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 491 2.1E-79 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_20915 3bae415a712fbbcf4332d9a30a327e14 513 SUPERFAMILY SSF103473 12 498 5.1E-75 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_16780 3ba41c54201ceb6021c01d7b29861825 169 Gene3D G3DSA:1.20.120.450 23 168 6.0E-32 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_16780 3ba41c54201ceb6021c01d7b29861825 169 SUPERFAMILY SSF109854 14 164 5.65E-36 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_16780 3ba41c54201ceb6021c01d7b29861825 169 Pfam PF12867 DinB superfamily 34 163 2.0E-19 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_18420 7d666cd74a433882a4daa4265bbb27e0 277 SUPERFAMILY SSF55729 141 267 2.52E-15 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_18420 7d666cd74a433882a4daa4265bbb27e0 277 Pfam PF08445 FR47-like protein 211 271 4.2E-9 T 01-11-2018 IPR013653 FR47-like GO:0016747 MLA2C4_18420 7d666cd74a433882a4daa4265bbb27e0 277 Gene3D G3DSA:3.40.630.30 138 273 4.6E-14 T 01-11-2018 MLA2C4_16760 ebababfe5430f2383cab96c8bac396b9 134 SUPERFAMILY SSF52788 4 129 9.81E-45 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MLA2C4_16760 ebababfe5430f2383cab96c8bac396b9 134 Gene3D G3DSA:3.40.50.2300 2 132 1.3E-53 T 01-11-2018 MLA2C4_16760 ebababfe5430f2383cab96c8bac396b9 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 129 6.3E-25 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_16760 ebababfe5430f2383cab96c8bac396b9 134 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 129 1.4E-64 T 01-11-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 MLA2C4_16760 ebababfe5430f2383cab96c8bac396b9 134 SMART SM00226 5 132 5.8E-57 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_16760 ebababfe5430f2383cab96c8bac396b9 134 Hamap MF_01624 Arsenate reductase [arsC]. 2 132 48.947 T 01-11-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 MLA2C4_10635 4402d9fbdf3a23c2698e27d31094e04d 142 Pfam PF00583 Acetyltransferase (GNAT) family 42 132 4.1E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10635 4402d9fbdf3a23c2698e27d31094e04d 142 SUPERFAMILY SSF55729 1 136 2.96E-20 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10635 4402d9fbdf3a23c2698e27d31094e04d 142 Gene3D G3DSA:3.40.630.30 1 140 2.3E-22 T 01-11-2018 MLA2C4_23265 be104a6b0804f25a1f48977dd567d223 250 SUPERFAMILY SSF69618 6 247 4.32E-60 T 01-11-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23265 be104a6b0804f25a1f48977dd567d223 250 Gene3D G3DSA:3.40.50.10090 145 249 3.8E-22 T 01-11-2018 MLA2C4_23265 be104a6b0804f25a1f48977dd567d223 250 Pfam PF02602 Uroporphyrinogen-III synthase HemD 21 243 9.3E-59 T 01-11-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MLA2C4_23265 be104a6b0804f25a1f48977dd567d223 250 Gene3D G3DSA:3.40.50.10090 3 125 4.7E-23 T 01-11-2018 MLA2C4_05175 99a98e76945a7d256f077ff5684159f2 188 Pfam PF14278 Transcriptional regulator C-terminal region 78 157 8.3E-15 T 01-11-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type MLA2C4_05175 99a98e76945a7d256f077ff5684159f2 188 SUPERFAMILY SSF46689 5 63 6.67E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05175 99a98e76945a7d256f077ff5684159f2 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 54 1.6E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05175 99a98e76945a7d256f077ff5684159f2 188 TIGRFAM TIGR02366 DHAK_reg: probable dihydroxyacetone kinase regulator 4 179 1.2E-78 T 01-11-2018 IPR012738 Transcription regulator DhaS MLA2C4_05175 99a98e76945a7d256f077ff5684159f2 188 Gene3D G3DSA:1.10.357.10 1 187 4.6E-52 T 01-11-2018 MLA2C4_04350 364f1cdd9259a42b35293fccd43304f2 106 Gene3D G3DSA:1.20.58.280 1 104 2.7E-38 T 01-11-2018 MLA2C4_04350 364f1cdd9259a42b35293fccd43304f2 106 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 98 1.6E-35 T 01-11-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 MLA2C4_04350 364f1cdd9259a42b35293fccd43304f2 106 PIRSF PIRSF000699 1 105 2.3E-37 T 01-11-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 MLA2C4_04350 364f1cdd9259a42b35293fccd43304f2 106 SUPERFAMILY SSF46973 5 99 1.83E-34 T 01-11-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 SUPERFAMILY SSF103473 9 463 6.02E-72 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 Pfam PF07690 Major Facilitator Superfamily 17 406 1.6E-48 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 416 6.6E-99 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 Gene3D G3DSA:1.20.1720.10 12 221 7.5E-51 T 01-11-2018 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 2.5E-5 T 01-11-2018 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 2.5E-5 T 01-11-2018 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 2.5E-5 T 01-11-2018 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 2.5E-5 T 01-11-2018 MLA2C4_12220 efb73557648e666b043d9c41746baf3c 479 Gene3D G3DSA:1.20.1250.20 256 466 1.9E-22 T 01-11-2018 MLA2C4_21855 b0b51c99db1e0914e0c51f911ab7496d 297 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 01-11-2018 IPR033749 Polyprenyl synthetase, conserved site MLA2C4_21855 b0b51c99db1e0914e0c51f911ab7496d 297 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 99 - T 01-11-2018 IPR033749 Polyprenyl synthetase, conserved site MLA2C4_21855 b0b51c99db1e0914e0c51f911ab7496d 297 Pfam PF00348 Polyprenyl synthetase 33 272 8.3E-59 T 01-11-2018 IPR000092 Polyprenyl synthetase GO:0008299 MLA2C4_21855 b0b51c99db1e0914e0c51f911ab7496d 297 Gene3D G3DSA:1.10.600.10 2 297 1.5E-104 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily MLA2C4_21855 b0b51c99db1e0914e0c51f911ab7496d 297 SUPERFAMILY SSF48576 9 276 1.35E-85 T 01-11-2018 IPR008949 Isoprenoid synthase domain superfamily MLA2C4_03775 97cb504eb9faeb25bff729bbb8a02c95 174 Gene3D G3DSA:3.40.50.300 2 173 1.4E-20 T 01-11-2018 MLA2C4_03775 97cb504eb9faeb25bff729bbb8a02c95 174 Pfam PF13671 AAA domain 6 135 6.7E-11 T 01-11-2018 MLA2C4_03775 97cb504eb9faeb25bff729bbb8a02c95 174 SUPERFAMILY SSF52540 5 172 4.96E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11580 f53610051f3fc46cc1a21c51af729d1a 118 Gene3D G3DSA:1.10.260.40 3 118 4.3E-26 T 01-11-2018 MLA2C4_11580 f53610051f3fc46cc1a21c51af729d1a 118 SUPERFAMILY SSF47413 1 69 1.34E-20 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_11580 f53610051f3fc46cc1a21c51af729d1a 118 Pfam PF01381 Helix-turn-helix 10 62 2.6E-18 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_11580 f53610051f3fc46cc1a21c51af729d1a 118 SMART SM00530 7 62 8.9E-19 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_25580 8eb58cf4411b1dc42d4605a1505182ec 127 Pfam PF03061 Thioesterase superfamily 35 113 3.6E-13 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_25580 8eb58cf4411b1dc42d4605a1505182ec 127 Gene3D G3DSA:3.10.129.10 1 127 2.5E-51 T 01-11-2018 MLA2C4_25580 8eb58cf4411b1dc42d4605a1505182ec 127 SUPERFAMILY SSF54637 5 125 9.05E-29 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_25580 8eb58cf4411b1dc42d4605a1505182ec 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 5 120 4.3E-35 T 01-11-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Pfam PF16736 Single Cache-like 33 149 9.5E-29 T 01-11-2018 IPR031967 PhoR, single Cache-like domain MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SUPERFAMILY SSF55874 416 582 3.41E-52 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SUPERFAMILY SSF47384 346 427 8.63E-22 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 426 2.6E-19 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 242 360 2.4E-10 T 01-11-2018 IPR000014 PAS domain MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SMART SM00388 360 427 2.8E-22 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Gene3D G3DSA:3.30.565.10 433 586 3.7E-50 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SMART SM00304 185 237 3.8E-5 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 582 7.4E-31 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Gene3D G3DSA:3.30.450.20 234 356 2.8E-17 T 01-11-2018 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SMART SM00387 472 584 1.6E-46 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 4.5E-21 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 4.5E-21 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 4.5E-21 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 4.5E-21 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Pfam PF00989 PAS fold 245 351 1.1E-12 T 01-11-2018 IPR013767 PAS fold GO:0006355 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SMART SM00091 244 311 4.2E-7 T 01-11-2018 IPR000014 PAS domain MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SUPERFAMILY SSF55785 233 352 3.05E-11 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Gene3D G3DSA:1.10.8.500 185 233 1.1E-5 T 01-11-2018 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 SUPERFAMILY SSF158472 188 235 1.7E-7 T 01-11-2018 MLA2C4_23835 1b8b85620d8ec058973a7c1eb0ce2ed0 587 Gene3D G3DSA:1.10.287.130 357 427 1.1E-26 T 01-11-2018 MLA2C4_16070 b08b8e9f796b37d765e89d129cc874f8 222 Gene3D G3DSA:3.40.50.300 2 210 2.7E-48 T 01-11-2018 MLA2C4_16070 b08b8e9f796b37d765e89d129cc874f8 222 SUPERFAMILY SSF52540 10 210 5.83E-25 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_16070 b08b8e9f796b37d765e89d129cc874f8 222 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 25 208 3.5E-10 T 01-11-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 Gene3D G3DSA:1.10.860.10 1 140 2.4E-33 T 01-11-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 SUPERFAMILY SSF48024 3 102 1.15E-21 T 01-11-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 Pfam PF00772 DnaB-like helicase N terminal domain 4 99 4.8E-21 T 01-11-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 3 426 2.3E-126 T 01-11-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 Pfam PF03796 DnaB-like helicase C terminal domain 168 425 8.9E-93 T 01-11-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 SUPERFAMILY SSF52540 166 420 9.25E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04985 cbfd9293599c51cee95aec9a1ffc17bf 429 Gene3D G3DSA:3.40.50.300 145 428 3.8E-102 T 01-11-2018 MLA2C4_19565 58e710483cb178dcbe735260ab1082be 202 SUPERFAMILY SSF53254 1 181 9.64E-28 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_19565 58e710483cb178dcbe735260ab1082be 202 Gene3D G3DSA:3.40.50.1240 1 187 1.1E-28 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_19565 58e710483cb178dcbe735260ab1082be 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 181 2.6E-25 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_19565 58e710483cb178dcbe735260ab1082be 202 PIRSF PIRSF000709 2 178 2.0E-6 T 01-11-2018 MLA2C4_14030 3c861532ec5051d698892bc3a0573503 427 SUPERFAMILY SSF103473 19 406 6.67E-47 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_14030 3c861532ec5051d698892bc3a0573503 427 Gene3D G3DSA:1.20.1250.20 16 405 6.8E-38 T 01-11-2018 MLA2C4_14030 3c861532ec5051d698892bc3a0573503 427 Pfam PF07690 Major Facilitator Superfamily 30 242 8.3E-20 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 5.4E-185 T 01-11-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Gene3D G3DSA:3.90.550.10 1 252 1.0E-77 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 SUPERFAMILY SSF53448 5 307 2.7E-66 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Pfam PF00483 Nucleotidyl transferase 6 210 2.0E-25 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.786 T 01-11-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Gene3D G3DSA:2.160.10.10 253 439 8.1E-54 T 01-11-2018 MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 2.1E-6 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 2.1E-7 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 301 6.4E-9 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_00280 9baf493cf43c51fe46282e5d08ee65da 459 SUPERFAMILY SSF51161 254 446 1.82E-51 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_19575 3ec5d20de0617f547ad28b2de033fc37 129 Gene3D G3DSA:3.10.180.10 2 128 2.4E-48 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_19575 3ec5d20de0617f547ad28b2de033fc37 129 SUPERFAMILY SSF54593 6 125 1.05E-17 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_19575 3ec5d20de0617f547ad28b2de033fc37 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 122 4.3E-6 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18305 ed58029a31591fb7ae8b273bfa2ed6f4 170 SUPERFAMILY SSF55729 12 155 1.63E-18 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_18305 ed58029a31591fb7ae8b273bfa2ed6f4 170 Gene3D G3DSA:3.40.630.30 28 151 1.7E-22 T 01-11-2018 MLA2C4_18305 ed58029a31591fb7ae8b273bfa2ed6f4 170 Pfam PF13302 Acetyltransferase (GNAT) domain 19 150 5.0E-12 T 01-11-2018 IPR000182 GNAT domain MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 Gene3D G3DSA:3.40.50.12740 2 210 1.4E-73 T 01-11-2018 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.3E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.3E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.3E-14 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 SUPERFAMILY SSF46894 138 210 1.02E-22 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 SMART SM00421 147 204 1.0E-24 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 SUPERFAMILY SSF52172 1 133 1.99E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 SMART SM00448 2 115 1.9E-33 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 Pfam PF00072 Response regulator receiver domain 4 116 1.9E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03350 5ad8dd7a4b77b69e004a232f6eac0858 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.9E-21 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 Gene3D G3DSA:3.40.50.2300 1 121 6.1E-36 T 01-11-2018 MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 Pfam PF00072 Response regulator receiver domain 3 111 1.1E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 Gene3D G3DSA:1.10.10.10 122 215 2.5E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 SMART SM00448 1 111 2.0E-38 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 SMART SM00862 139 210 1.4E-21 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 SUPERFAMILY SSF52172 1 169 7.39E-38 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_15140 c5cb0668e2b9f0cc9321651b7f2f6ec7 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 140 210 1.9E-21 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_08095 f80d054575b65c20c0a03250f632053e 278 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 259 3.0E-114 T 01-11-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MLA2C4_08095 f80d054575b65c20c0a03250f632053e 278 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 1.4E-119 T 01-11-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MLA2C4_08095 f80d054575b65c20c0a03250f632053e 278 PIRSF PIRSF000388 1 266 5.4E-111 T 01-11-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MLA2C4_08095 f80d054575b65c20c0a03250f632053e 278 Gene3D G3DSA:3.20.20.60 2 273 2.1E-119 T 01-11-2018 MLA2C4_08095 f80d054575b65c20c0a03250f632053e 278 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 43.647 T 01-11-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MLA2C4_08095 f80d054575b65c20c0a03250f632053e 278 SUPERFAMILY SSF51621 3 263 3.85E-109 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MLA2C4_01670 6a3ba9c2ae99441d60f97dcf814489a3 258 Pfam PF13489 Methyltransferase domain 60 219 6.6E-11 T 01-11-2018 MLA2C4_01670 6a3ba9c2ae99441d60f97dcf814489a3 258 SUPERFAMILY SSF53335 17 201 4.18E-18 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_01670 6a3ba9c2ae99441d60f97dcf814489a3 258 Gene3D G3DSA:3.40.50.150 43 253 3.3E-16 T 01-11-2018 MLA2C4_22960 939422cc6232ada2da4d496b7e91cf45 255 SUPERFAMILY SSF69572 4 241 9.29E-63 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_22960 939422cc6232ada2da4d496b7e91cf45 255 Gene3D G3DSA:3.40.50.720 1 255 4.1E-82 T 01-11-2018 MLA2C4_22960 939422cc6232ada2da4d496b7e91cf45 255 Pfam PF00899 ThiF family 6 158 1.5E-37 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 SUPERFAMILY SSF49478 561 627 3.49E-7 T 01-11-2018 MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 Gene3D G3DSA:2.60.40.10 555 686 9.1E-20 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 89 128 2.7E-12 T 01-11-2018 IPR023849 Uncharacterised domain CHP03934, TQXA MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 Gene3D G3DSA:2.60.40.10 461 554 5.4E-20 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 Gene3D G3DSA:2.60.40.10 366 460 6.7E-21 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 Gene3D G3DSA:2.60.40.10 281 365 1.0E-15 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 SUPERFAMILY SSF49478 379 445 2.59E-7 T 01-11-2018 MLA2C4_26080 5b1f542823d39b07bc89b2c151d2e89b 718 SUPERFAMILY SSF49478 470 536 2.98E-7 T 01-11-2018 MLA2C4_16835 84a70094f5c2814b007368215cca482e 123 Pfam PF06993 Protein of unknown function (DUF1304) 11 120 9.9E-40 T 01-11-2018 IPR009732 Protein of unknown function DUF1304 MLA2C4_11450 3e0ddb87fc02ecaffc6cb1ea3b0ace04 130 PIRSF PIRSF034303 1 130 1.5E-48 T 01-11-2018 IPR012543 Protein of unknown function DUF1694 MLA2C4_11450 3e0ddb87fc02ecaffc6cb1ea3b0ace04 130 Pfam PF07997 Protein of unknown function (DUF1694) 4 119 2.2E-37 T 01-11-2018 IPR012543 Protein of unknown function DUF1694 MLA2C4_11450 3e0ddb87fc02ecaffc6cb1ea3b0ace04 130 Gene3D G3DSA:3.30.1330.30 1 130 1.8E-44 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_11450 3e0ddb87fc02ecaffc6cb1ea3b0ace04 130 SUPERFAMILY SSF160515 4 127 4.58E-39 T 01-11-2018 MLA2C4_12390 59d911e81f7b11303e54ecc7da1c015f 743 SUPERFAMILY SSF82866 541 728 1.83E-28 T 01-11-2018 MLA2C4_12390 59d911e81f7b11303e54ecc7da1c015f 743 Gene3D G3DSA:1.20.1640.10 184 362 7.6E-7 T 01-11-2018 MLA2C4_12390 59d911e81f7b11303e54ecc7da1c015f 743 Pfam PF03176 MMPL family 496 730 2.0E-46 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MLA2C4_12390 59d911e81f7b11303e54ecc7da1c015f 743 Pfam PF03176 MMPL family 51 405 7.3E-62 T 01-11-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MLA2C4_12390 59d911e81f7b11303e54ecc7da1c015f 743 SUPERFAMILY SSF82866 174 360 2.62E-29 T 01-11-2018 MLA2C4_23450 2bf5bb35e389c28706326b54b307e9cc 294 SUPERFAMILY SSF52540 3 226 7.03E-56 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23450 2bf5bb35e389c28706326b54b307e9cc 294 Gene3D G3DSA:3.40.50.300 1 233 1.3E-58 T 01-11-2018 MLA2C4_23450 2bf5bb35e389c28706326b54b307e9cc 294 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_23450 2bf5bb35e389c28706326b54b307e9cc 294 Pfam PF00005 ABC transporter 19 157 3.3E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_23450 2bf5bb35e389c28706326b54b307e9cc 294 SMART SM00382 27 205 1.6E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23450 2bf5bb35e389c28706326b54b307e9cc 294 Pfam PF13732 Domain of unknown function (DUF4162) 211 291 1.8E-14 T 01-11-2018 IPR025302 Domain of unknown function DUF4162 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 Pfam PF07690 Major Facilitator Superfamily 18 411 1.9E-52 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 Gene3D G3DSA:1.20.1720.10 14 247 6.2E-38 T 01-11-2018 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 Gene3D G3DSA:1.20.1250.20 262 487 4.4E-23 T 01-11-2018 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 7.2E-11 T 01-11-2018 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 7.2E-11 T 01-11-2018 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 304 328 7.2E-11 T 01-11-2018 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 7.2E-11 T 01-11-2018 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 450 4.2E-120 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_16860 73fb675b923a8478b15c64f60e3a7879 492 SUPERFAMILY SSF103473 7 479 9.55E-67 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_09565 e6051fe250a9075ea46ef26b0ed00d54 313 Gene3D G3DSA:2.70.70.10 127 285 5.3E-21 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_09565 e6051fe250a9075ea46ef26b0ed00d54 313 SUPERFAMILY SSF51261 146 252 3.14E-17 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_09565 e6051fe250a9075ea46ef26b0ed00d54 313 Pfam PF01551 Peptidase family M23 158 250 1.7E-15 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_23550 44372629544095f9cbbaae6a7840aacd 678 Gene3D G3DSA:1.10.3470.10 8 336 1.3E-87 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_23550 44372629544095f9cbbaae6a7840aacd 678 Gene3D G3DSA:1.10.3470.10 353 677 1.2E-90 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_23550 44372629544095f9cbbaae6a7840aacd 678 SUPERFAMILY SSF81345 352 672 1.22E-79 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_23550 44372629544095f9cbbaae6a7840aacd 678 Pfam PF01032 FecCD transport family 20 329 5.6E-88 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_23550 44372629544095f9cbbaae6a7840aacd 678 Pfam PF01032 FecCD transport family 364 672 1.7E-88 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_23550 44372629544095f9cbbaae6a7840aacd 678 SUPERFAMILY SSF81345 5 329 7.19E-72 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_03745 ae6f0b4e1626521d626f5e9baccaffd5 466 Pfam PF07670 Nucleoside recognition 309 434 8.9E-18 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_03745 ae6f0b4e1626521d626f5e9baccaffd5 466 Pfam PF07670 Nucleoside recognition 139 228 4.0E-9 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_03745 ae6f0b4e1626521d626f5e9baccaffd5 466 Pfam PF07664 Ferrous iron transport protein B C terminus 251 300 2.9E-14 T 01-11-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 MLA2C4_00615 8daf4223f968760f527dcb7373fa85a1 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.479 T 01-11-2018 IPR022973 Ribosomal protein L10 MLA2C4_00615 8daf4223f968760f527dcb7373fa85a1 166 Gene3D G3DSA:3.30.70.1730 1 165 2.6E-43 T 01-11-2018 MLA2C4_00615 8daf4223f968760f527dcb7373fa85a1 166 Pfam PF00466 Ribosomal protein L10 6 100 3.9E-30 T 01-11-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MLA2C4_00615 8daf4223f968760f527dcb7373fa85a1 166 SUPERFAMILY SSF160369 5 160 3.53E-55 T 01-11-2018 MLA2C4_00615 8daf4223f968760f527dcb7373fa85a1 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 26 143 0.006 T 01-11-2018 MLA2C4_00615 8daf4223f968760f527dcb7373fa85a1 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 01-11-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 Gene3D G3DSA:3.90.230.10 1 248 5.2E-98 T 01-11-2018 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 3.3E-18 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.3E-18 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.3E-18 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 3.3E-18 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 SUPERFAMILY SSF55920 3 246 4.71E-79 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 37.471 T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 Pfam PF00557 Metallopeptidase family M24 12 239 5.8E-51 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 247 2.8E-87 T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_08225 251a568edfc3cb7565f76c8ed5dfd64f 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 01-11-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_11105 e7c0f4f93e0b5770a9c0406095945ec0 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 176 1.6E-5 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_11105 e7c0f4f93e0b5770a9c0406095945ec0 220 Gene3D G3DSA:1.10.150.240 16 82 4.8E-66 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_11105 e7c0f4f93e0b5770a9c0406095945ec0 220 Gene3D G3DSA:3.40.50.1000 5 204 4.8E-66 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_11105 e7c0f4f93e0b5770a9c0406095945ec0 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 6.2E-29 T 01-11-2018 MLA2C4_11105 e7c0f4f93e0b5770a9c0406095945ec0 220 SUPERFAMILY SSF56784 3 213 4.76E-54 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 Gene3D G3DSA:3.30.1360.60 466 545 4.5E-25 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 2 545 0.0 T 01-11-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199 MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 SUPERFAMILY SSF55604 469 544 2.09E-19 T 01-11-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 Pfam PF02378 Phosphotransferase system, EIIC 13 377 2.8E-56 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 437 529 1.9E-16 T 01-11-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 482 499 - T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_02195 4ee53c9b46e638deeca20efbd498a529 545 Pfam PF00367 phosphotransferase system, EIIB 472 499 4.0E-14 T 01-11-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 Gene3D G3DSA:2.30.30.40 84 141 7.4E-14 T 01-11-2018 MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 Pfam PF06725 3D domain 236 296 6.1E-21 T 01-11-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 Pfam PF08239 Bacterial SH3 domain 91 138 7.7E-8 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 Pfam PF08239 Bacterial SH3 domain 32 80 7.1E-11 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 Gene3D G3DSA:2.30.30.40 19 83 2.1E-15 T 01-11-2018 MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 SUPERFAMILY SSF50685 234 286 6.28E-11 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 Gene3D G3DSA:2.40.40.10 142 290 1.5E-9 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 SMART SM00287 85 144 4.0E-7 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_27100 8e6c4124ef05de15838b2a18e8d9c87a 296 SMART SM00287 23 84 1.4E-8 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_07650 38a6fccad3d6411259c27f72da5ca0d0 170 SUPERFAMILY SSF51206 3 113 5.5E-18 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like MLA2C4_07650 38a6fccad3d6411259c27f72da5ca0d0 170 Gene3D G3DSA:1.10.10.10 118 169 2.0E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_07650 38a6fccad3d6411259c27f72da5ca0d0 170 SUPERFAMILY SSF46785 120 163 7.26E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_07650 38a6fccad3d6411259c27f72da5ca0d0 170 Pfam PF00027 Cyclic nucleotide-binding domain 3 72 1.0E-10 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_07650 38a6fccad3d6411259c27f72da5ca0d0 170 Gene3D G3DSA:2.60.120.10 1 115 3.7E-16 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_21105 0f2eef741da8d68a97ff349496c9474e 392 Gene3D G3DSA:3.90.1150.10 30 384 1.3E-114 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_21105 0f2eef741da8d68a97ff349496c9474e 392 Pfam PF00155 Aminotransferase class I and II 34 384 3.3E-69 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_21105 0f2eef741da8d68a97ff349496c9474e 392 Gene3D G3DSA:3.40.640.10 45 286 1.3E-114 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_21105 0f2eef741da8d68a97ff349496c9474e 392 SUPERFAMILY SSF53383 6 387 5.57E-104 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Gene3D G3DSA:2.30.40.20 29 82 1.1E-60 T 01-11-2018 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 SUPERFAMILY SSF56672 6 242 6.85E-81 T 01-11-2018 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 SUPERFAMILY SSF100879 249 349 8.79E-24 T 01-11-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Gene3D G3DSA:3.30.1490.100 250 358 7.8E-23 T 01-11-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Hamap MF_01113 DNA polymerase IV [dinB]. 9 361 37.563 T 01-11-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Pfam PF00817 impB/mucB/samB family 15 162 1.9E-49 T 01-11-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Gene3D G3DSA:3.30.70.270 12 172 1.1E-60 T 01-11-2018 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Pfam PF11798 IMS family HHH motif 176 205 8.7E-8 T 01-11-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 351 1.9E-17 T 01-11-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MLA2C4_21680 e1209e7dc27bba49b588622303e2c192 412 Gene3D G3DSA:1.10.150.20 177 244 4.4E-15 T 01-11-2018 MLA2C4_14975 a08c6c894d2ff760bc0fef5cf336ffd4 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 01-11-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MLA2C4_14975 a08c6c894d2ff760bc0fef5cf336ffd4 494 SUPERFAMILY SSF53720 12 492 2.75E-182 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_14975 a08c6c894d2ff760bc0fef5cf336ffd4 494 Pfam PF00171 Aldehyde dehydrogenase family 33 489 3.5E-187 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_14975 a08c6c894d2ff760bc0fef5cf336ffd4 494 Gene3D G3DSA:3.40.605.10 24 487 1.2E-208 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_14975 a08c6c894d2ff760bc0fef5cf336ffd4 494 Gene3D G3DSA:3.40.309.10 270 459 1.2E-208 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 Pfam PF00912 Transglycosylase 61 234 2.0E-61 T 01-11-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 SUPERFAMILY SSF56601 216 657 1.74E-120 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 Pfam PF00905 Penicillin binding protein transpeptidase domain 325 598 5.7E-33 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 Gene3D G3DSA:1.10.3810.10 61 256 2.6E-74 T 01-11-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 Gene3D G3DSA:3.40.710.10 257 663 2.2E-115 T 01-11-2018 MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 70 603 4.5E-182 T 01-11-2018 MLA2C4_27820 d9d3ee3b9616975ca5538ad94dfdcf2f 683 SUPERFAMILY SSF53955 47 261 1.35E-74 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 Gene3D G3DSA:3.40.50.720 1 127 3.2E-38 T 01-11-2018 MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 Pfam PF13241 Putative NAD(P)-binding 4 112 3.1E-26 T 01-11-2018 MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 SUPERFAMILY SSF75615 106 189 1.01E-20 T 01-11-2018 MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 Gene3D G3DSA:1.10.8.610 128 201 7.1E-24 T 01-11-2018 MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 Pfam PF14824 Sirohaem biosynthesis protein central 116 142 1.3E-9 T 01-11-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 187 3.4E-39 T 01-11-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MLA2C4_07545 f63fc656fa9ee6da3bb5d95fa5491b4a 205 SUPERFAMILY SSF51735 1 106 2.56E-18 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 141 1.1E-39 T 01-11-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 350 28.945 T 01-11-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 Gene3D G3DSA:3.40.50.2000 175 337 5.5E-40 T 01-11-2018 MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 SUPERFAMILY SSF53756 2 349 6.28E-96 T 01-11-2018 MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 349 7.4E-84 T 01-11-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 187 340 2.8E-31 T 01-11-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MLA2C4_22235 6545742d0ef5413bde775bfb5eaf6e34 352 Gene3D G3DSA:3.40.50.2000 1 174 1.6E-60 T 01-11-2018 MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 Pfam PF00825 Ribonuclease P 1 107 2.4E-36 T 01-11-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 SUPERFAMILY SSF54211 1 109 2.78E-34 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 108 2.6E-33 T 01-11-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 01-11-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 Gene3D G3DSA:3.30.230.10 1 114 7.2E-38 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 20.459 T 01-11-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MLA2C4_28475 58e6dc054304d3edcfd48efb9b681d2f 115 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 114 2.0E-56 T 01-11-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MLA2C4_02165 7d4dd3b41db4f3d55aaea990cd77c062 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_02165 7d4dd3b41db4f3d55aaea990cd77c062 240 Gene3D G3DSA:3.40.50.300 1 239 1.1E-77 T 01-11-2018 MLA2C4_02165 7d4dd3b41db4f3d55aaea990cd77c062 240 PIRSF PIRSF039085 1 240 2.9E-116 T 01-11-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MLA2C4_02165 7d4dd3b41db4f3d55aaea990cd77c062 240 SUPERFAMILY SSF52540 1 235 4.28E-79 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02165 7d4dd3b41db4f3d55aaea990cd77c062 240 Pfam PF00005 ABC transporter 17 165 4.8E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_02165 7d4dd3b41db4f3d55aaea990cd77c062 240 SMART SM00382 26 213 7.9E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_05310 7fb52d528a003bc2253f0640b8be490c 112 Gene3D G3DSA:3.30.750.24 2 111 6.3E-27 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_05310 7fb52d528a003bc2253f0640b8be490c 112 Pfam PF01740 STAS domain 15 102 5.5E-17 T 01-11-2018 IPR002645 STAS domain MLA2C4_05310 7fb52d528a003bc2253f0640b8be490c 112 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 106 1.1E-28 T 01-11-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MLA2C4_05310 7fb52d528a003bc2253f0640b8be490c 112 SUPERFAMILY SSF52091 6 107 1.96E-24 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 SMART SM00382 29 212 9.2E-20 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 Pfam PF00005 ABC transporter 23 162 2.2E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 Pfam PF08402 TOBE domain 248 325 2.5E-8 T 01-11-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 SUPERFAMILY SSF50331 241 326 3.57E-7 T 01-11-2018 IPR008995 Molybdate/tungstate binding, C-terminal MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 SUPERFAMILY SSF52540 4 240 1.05E-86 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06840 67b46207636d9bc1a8dc0df57586b016 327 Gene3D G3DSA:3.40.50.300 1 239 3.8E-78 T 01-11-2018 MLA2C4_15505 2e7fa48548340cc64f58c47f28396119 181 Pfam PF13302 Acetyltransferase (GNAT) domain 7 145 1.6E-23 T 01-11-2018 IPR000182 GNAT domain MLA2C4_15505 2e7fa48548340cc64f58c47f28396119 181 Gene3D G3DSA:3.40.630.30 3 180 5.3E-40 T 01-11-2018 MLA2C4_15505 2e7fa48548340cc64f58c47f28396119 181 SUPERFAMILY SSF55729 6 171 1.8E-37 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 SUPERFAMILY SSF50331 244 324 6.29E-6 T 01-11-2018 IPR008995 Molybdate/tungstate binding, C-terminal MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 Gene3D G3DSA:3.40.50.300 2 303 4.3E-82 T 01-11-2018 MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 SMART SM00382 29 212 5.2E-21 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 2 248 1.8E-139 T 01-11-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 Pfam PF08402 TOBE domain 249 324 9.6E-7 T 01-11-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 Pfam PF00005 ABC transporter 20 162 7.3E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_07025 40e181741fed5bfc4c7a0882243baba4 333 SUPERFAMILY SSF52540 5 241 3.55E-88 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 4.0E-35 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 4.0E-35 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 147 175 4.0E-35 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 4.0E-35 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 219 2.7E-56 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 ProSitePatterns PS01218 TatC family signature. 147 166 - T 01-11-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 214 1.6E-51 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_11230 246b90a38f00e00705d76e66da7bc1c6 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 231 15.499 T 01-11-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MLA2C4_14375 c70ba798c83995e51543559c4b915efd 187 SUPERFAMILY SSF55729 6 175 4.38E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14375 c70ba798c83995e51543559c4b915efd 187 Gene3D G3DSA:3.40.630.30 2 155 7.2E-16 T 01-11-2018 MLA2C4_14375 c70ba798c83995e51543559c4b915efd 187 Pfam PF00583 Acetyltransferase (GNAT) family 54 154 8.6E-9 T 01-11-2018 IPR000182 GNAT domain MLA2C4_24505 5331758f19cd36d78a4851b90587c118 143 Gene3D G3DSA:3.30.530.20 1 143 5.5E-43 T 01-11-2018 IPR023393 START-like domain superfamily MLA2C4_24505 5331758f19cd36d78a4851b90587c118 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 142 1.6E-12 T 01-11-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MLA2C4_24505 5331758f19cd36d78a4851b90587c118 143 SUPERFAMILY SSF55961 3 143 8.36E-43 T 01-11-2018 MLA2C4_19345 d60b2971f6d8e37f3f0a0727bff8437d 246 Pfam PF02706 Chain length determinant protein 4 61 2.5E-12 T 01-11-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 Pfam PF04545 Sigma-70, region 4 205 252 3.0E-14 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 Pfam PF04542 Sigma-70 region 2 35 104 5.0E-17 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 Gene3D G3DSA:1.20.120.1810 1 103 3.3E-19 T 01-11-2018 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 2 255 3.5E-143 T 01-11-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 253 1.1E-86 T 01-11-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 SUPERFAMILY SSF88659 182 253 4.3E-13 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 SUPERFAMILY SSF88946 12 104 6.28E-28 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 Gene3D G3DSA:1.20.140.160 107 254 2.7E-31 T 01-11-2018 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 253 4.0E-33 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 SUPERFAMILY SSF88659 108 178 2.27E-15 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 Pfam PF04539 Sigma-70 region 3 117 188 5.9E-15 T 01-11-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 PRINTS PR00046 Major sigma-70 factor signature 224 239 3.3E-7 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 PRINTS PR00046 Major sigma-70 factor signature 59 72 3.3E-7 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 PRINTS PR00046 Major sigma-70 factor signature 207 219 3.3E-7 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05320 658cfa752da040633cc71cb77f338290 258 PRINTS PR00046 Major sigma-70 factor signature 239 250 3.3E-7 T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_01565 9146e2cde2aa956628111ba37c3f6cc7 249 Pfam PF02517 CAAX protease self-immunity 131 216 2.0E-17 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_17560 9738f3df3ad690eeaefb1a8e0656c6c4 252 Pfam PF00005 ABC transporter 25 174 6.0E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_17560 9738f3df3ad690eeaefb1a8e0656c6c4 252 SMART SM00382 34 223 2.3E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17560 9738f3df3ad690eeaefb1a8e0656c6c4 252 SUPERFAMILY SSF52540 5 230 4.09E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17560 9738f3df3ad690eeaefb1a8e0656c6c4 252 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_17560 9738f3df3ad690eeaefb1a8e0656c6c4 252 Gene3D G3DSA:3.40.50.300 3 239 8.8E-64 T 01-11-2018 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 25 175 2.2E-58 T 01-11-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 37 68 - T 01-11-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 SUPERFAMILY SSF54534 101 174 3.66E-21 T 01-11-2018 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 Pfam PF03449 Transcription elongation factor, N-terminal 25 94 1.3E-32 T 01-11-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 Hamap MF_00105 Transcription elongation factor GreA [greA]. 22 175 32.697 T 01-11-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 Gene3D G3DSA:3.10.50.30 96 175 6.3E-26 T 01-11-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 Gene3D G3DSA:1.10.287.180 21 95 2.2E-32 T 01-11-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 102 175 1.4E-26 T 01-11-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 140 156 - T 01-11-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 PIRSF PIRSF006092 18 175 1.7E-52 T 01-11-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MLA2C4_22845 2fdd8c8acc7e60cecd4c40288d03e92a 175 SUPERFAMILY SSF46557 22 95 1.96E-27 T 01-11-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MLA2C4_26415 392a548a31179891db5e350a3fa60ac7 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 112 6.3E-24 T 01-11-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MLA2C4_26415 392a548a31179891db5e350a3fa60ac7 118 TIGRFAM TIGR00494 crcB: protein CrcB 5 114 1.3E-23 T 01-11-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MLA2C4_26415 392a548a31179891db5e350a3fa60ac7 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 19.262 T 01-11-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 01-11-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 SUPERFAMILY SSF143034 2 62 1.57E-21 T 01-11-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 Gene3D G3DSA:2.40.50.530 1 63 2.9E-21 T 01-11-2018 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 Pfam PF01632 Ribosomal protein L35 2 62 1.8E-24 T 01-11-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 2.8E-25 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-20 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-20 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-20 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MLA2C4_23765 37c3724aa41534736ba1c5a70cff8550 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.5 T 01-11-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MLA2C4_19270 2a8aa36586f3694ee1e81effece7b35d 325 Gene3D G3DSA:3.30.470.20 192 312 7.4E-39 T 01-11-2018 MLA2C4_19270 2a8aa36586f3694ee1e81effece7b35d 325 Gene3D G3DSA:3.40.50.20 2 122 8.9E-38 T 01-11-2018 MLA2C4_19270 2a8aa36586f3694ee1e81effece7b35d 325 SUPERFAMILY SSF56059 119 301 5.89E-32 T 01-11-2018 MLA2C4_19270 2a8aa36586f3694ee1e81effece7b35d 325 Pfam PF02655 ATP-grasp domain 117 275 4.7E-25 T 01-11-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 MLA2C4_19270 2a8aa36586f3694ee1e81effece7b35d 325 Gene3D G3DSA:3.30.1490.20 136 184 2.4E-7 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 209 1.8E-76 T 01-11-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 SUPERFAMILY SSF160467 2 102 1.57E-16 T 01-11-2018 MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 Gene3D G3DSA:2.40.100.10 96 237 6.3E-59 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 220 3.6E-71 T 01-11-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 SUPERFAMILY SSF50891 98 227 6.07E-47 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 SMART SM00796 1 211 1.1E-97 T 01-11-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MLA2C4_16185 84105697fbbc3d99aebaebafed178114 237 Gene3D G3DSA:3.30.1360.40 1 94 2.3E-25 T 01-11-2018 MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 SUPERFAMILY SSF53335 144 361 4.17E-39 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 Gene3D G3DSA:3.30.2130.30 8 246 1.1E-121 T 01-11-2018 MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 01-11-2018 IPR000241 Putative RNA methylase domain MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 Pfam PF02926 THUMP domain 20 154 1.7E-16 T 01-11-2018 IPR004114 THUMP domain GO:0003723 MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 Gene3D G3DSA:3.40.50.150 161 365 1.1E-121 T 01-11-2018 MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 1.1E-64 T 01-11-2018 IPR000241 Putative RNA methylase domain MLA2C4_08200 6190b900967bdf62d6c5188839782a67 379 SMART SM00981 57 155 2.5E-8 T 01-11-2018 IPR004114 THUMP domain GO:0003723 MLA2C4_10170 6f46a7523a0846a3c08744855876c6ff 626 Pfam PF02687 FtsX-like permease family 84 177 9.7E-8 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_10170 6f46a7523a0846a3c08744855876c6ff 626 PIRSF PIRSF018968 1 623 1.8E-135 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_02985 343b4d2ac6752fbea68660c0956a5cd0 524 Gene3D G3DSA:3.30.479.30 77 193 1.4E-36 T 01-11-2018 MLA2C4_02985 343b4d2ac6752fbea68660c0956a5cd0 524 Pfam PF01145 SPFH domain / Band 7 family 28 220 5.7E-23 T 01-11-2018 IPR001107 Band 7 domain MLA2C4_02985 343b4d2ac6752fbea68660c0956a5cd0 524 SMART SM00244 34 203 0.0021 T 01-11-2018 IPR001107 Band 7 domain MLA2C4_02985 343b4d2ac6752fbea68660c0956a5cd0 524 Pfam PF15975 Flotillin 378 471 6.9E-14 T 01-11-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 MLA2C4_02985 343b4d2ac6752fbea68660c0956a5cd0 524 SUPERFAMILY SSF117892 68 210 1.24E-33 T 01-11-2018 IPR036013 Band 7/SPFH domain superfamily MLA2C4_16470 04ed9c77d2a628ffe94181cbbbb427d5 385 Gene3D G3DSA:3.40.710.10 47 385 4.5E-133 T 01-11-2018 MLA2C4_16470 04ed9c77d2a628ffe94181cbbbb427d5 385 Pfam PF00144 Beta-lactamase 62 378 6.8E-65 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_16470 04ed9c77d2a628ffe94181cbbbb427d5 385 SUPERFAMILY SSF56601 60 375 7.92E-79 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_05720 af3e55fae8238fa8972c6d2e423b671c 450 Pfam PF13218 Protein of unknown function (DUF4026) 17 339 1.4E-160 T 01-11-2018 IPR025102 Protein of unknown function DUF4026 MLA2C4_05720 af3e55fae8238fa8972c6d2e423b671c 450 Pfam PF10077 Uncharacterized protein conserved in bacteria (DUF2314) 348 436 2.1E-9 T 01-11-2018 IPR018756 Domain of unknown function DUF2314 MLA2C4_12395 7e78732c5093f44a7773d16e68954914 60 Pfam PF13213 Protein of unknown function (DUF4021) 9 54 2.9E-28 T 01-11-2018 IPR025094 Protein of unknown function DUF4021 MLA2C4_16495 3cc0284a5c1e13e177b5d4c880c2d82c 214 Pfam PF00857 Isochorismatase family 14 165 1.6E-21 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_16495 3cc0284a5c1e13e177b5d4c880c2d82c 214 SUPERFAMILY SSF52499 4 203 4.58E-53 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_16495 3cc0284a5c1e13e177b5d4c880c2d82c 214 Gene3D G3DSA:3.40.50.850 1 208 1.4E-51 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_19465 e635eb72eb87ae2d06fe0df259a4ac99 271 Pfam PF01226 Formate/nitrite transporter 9 248 3.3E-76 T 01-11-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_19465 e635eb72eb87ae2d06fe0df259a4ac99 271 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 161 171 - T 01-11-2018 IPR024002 Formate/nitrite transporter, conserved site MLA2C4_19465 e635eb72eb87ae2d06fe0df259a4ac99 271 Gene3D G3DSA:1.20.1080.10 4 262 5.4E-82 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_22670 f7494e3d6521a36c9d2f9b8d25e7de14 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 5.6E-21 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22670 f7494e3d6521a36c9d2f9b8d25e7de14 49 Pfam PF00471 Ribosomal protein L33 3 49 3.6E-23 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22670 f7494e3d6521a36c9d2f9b8d25e7de14 49 SUPERFAMILY SSF57829 1 49 1.83E-19 T 01-11-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MLA2C4_22670 f7494e3d6521a36c9d2f9b8d25e7de14 49 Gene3D G3DSA:2.20.28.120 1 49 1.3E-24 T 01-11-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22670 f7494e3d6521a36c9d2f9b8d25e7de14 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 01-11-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_22670 f7494e3d6521a36c9d2f9b8d25e7de14 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.619 T 01-11-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 Gene3D G3DSA:1.20.272.10 242 361 3.3E-9 T 01-11-2018 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 Pfam PF13177 DNA polymerase III, delta subunit 20 178 9.6E-47 T 01-11-2018 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 6.2E-148 T 01-11-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 Gene3D G3DSA:3.40.50.300 13 177 1.2E-108 T 01-11-2018 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 360 1.2E-13 T 01-11-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 SMART SM00382 37 185 2.2E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 7.1E-6 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 7.1E-6 T 01-11-2018 IPR001270 ClpA/B family GO:0005524 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 SUPERFAMILY SSF48019 244 360 1.79E-28 T 01-11-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 SUPERFAMILY SSF52540 31 223 8.3E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00125 243916c57b058ffcee0026b182b34fa7 562 Gene3D G3DSA:1.10.8.60 8 238 1.2E-108 T 01-11-2018 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 Gene3D G3DSA:3.90.550.10 95 313 1.5E-83 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 Pfam PF03552 Cellulose synthase 277 393 5.0E-7 T 01-11-2018 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 SUPERFAMILY SSF141371 530 625 9.81E-10 T 01-11-2018 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 SUPERFAMILY SSF53448 95 385 3.42E-54 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 Gene3D G3DSA:2.40.10.220 525 628 3.2E-8 T 01-11-2018 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 SUPERFAMILY SSF141371 663 740 6.67E-9 T 01-11-2018 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 PRINTS PR01439 Cellulose synthase subunit A signature 112 131 5.0E-16 T 01-11-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 PRINTS PR01439 Cellulose synthase subunit A signature 353 379 5.0E-16 T 01-11-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 PRINTS PR01439 Cellulose synthase subunit A signature 193 217 5.0E-16 T 01-11-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 PRINTS PR01439 Cellulose synthase subunit A signature 462 486 5.0E-16 T 01-11-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 PRINTS PR01439 Cellulose synthase subunit A signature 498 519 5.0E-16 T 01-11-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 PRINTS PR01439 Cellulose synthase subunit A signature 30 50 5.0E-16 T 01-11-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 Pfam PF07238 PilZ domain 660 740 3.4E-8 T 01-11-2018 IPR009875 PilZ domain GO:0035438 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 Pfam PF07238 PilZ domain 527 623 4.5E-8 T 01-11-2018 IPR009875 PilZ domain GO:0035438 MLA2C4_08790 9f8edd923334f6a3f63ace2158c148bf 741 Pfam PF00535 Glycosyl transferase family 2 106 276 1.6E-34 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_17515 e03e12a96c737de26ac5351cc6ff4b7b 240 Gene3D G3DSA:3.40.630.30 97 239 1.2E-10 T 01-11-2018 MLA2C4_17515 e03e12a96c737de26ac5351cc6ff4b7b 240 SUPERFAMILY SSF55729 112 238 4.43E-13 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 SUPERFAMILY SSF54752 65 123 1.44E-21 T 01-11-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 PRINTS PR00142 RecA protein signature 94 111 1.3E-36 T 01-11-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 PRINTS PR00142 RecA protein signature 40 69 1.3E-36 T 01-11-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 PRINTS PR00142 RecA protein signature 7 35 1.3E-36 T 01-11-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 Gene3D G3DSA:3.30.250.10 65 140 1.4E-27 T 01-11-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 ProSitePatterns PS00321 recA signature. 10 18 - T 01-11-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 Pfam PF00154 recA bacterial DNA recombination protein 2 65 1.7E-28 T 01-11-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 Gene3D G3DSA:3.40.50.300 1 64 3.9E-15 T 01-11-2018 MLA2C4_19760 2cdc8d287e81eb67e6260810594e162d 141 SUPERFAMILY SSF52540 4 64 8.06E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 436 50.636 T 01-11-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 SUPERFAMILY SSF52540 73 360 2.11E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 Gene3D G3DSA:3.40.50.300 2 218 6.9E-68 T 01-11-2018 MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 Pfam PF00271 Helicase conserved C-terminal domain 233 341 7.0E-25 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 SMART SM00490 260 341 6.0E-29 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 Gene3D G3DSA:3.40.50.300 219 436 4.3E-46 T 01-11-2018 MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 Pfam PF00270 DEAD/DEAH box helicase 28 196 3.4E-42 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_22400 72e6101a023312830288d9340484ddf9 436 SMART SM00487 23 224 3.0E-53 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_26115 34ebc5ca32e9573f314fe4d8d4dc013e 372 Pfam PF00589 Phage integrase family 173 352 5.6E-30 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_26115 34ebc5ca32e9573f314fe4d8d4dc013e 372 Gene3D G3DSA:1.10.150.130 26 131 3.4E-15 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_26115 34ebc5ca32e9573f314fe4d8d4dc013e 372 SUPERFAMILY SSF56349 29 360 3.24E-42 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_26115 34ebc5ca32e9573f314fe4d8d4dc013e 372 Gene3D G3DSA:1.10.443.10 165 371 1.1E-42 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_26115 34ebc5ca32e9573f314fe4d8d4dc013e 372 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 29 120 3.7E-7 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_19330 bc49c9b7b175cb398811225b2d386088 385 SUPERFAMILY SSF53756 19 370 6.63E-75 T 01-11-2018 MLA2C4_19330 bc49c9b7b175cb398811225b2d386088 385 Pfam PF00534 Glycosyl transferases group 1 185 350 1.6E-42 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_19330 bc49c9b7b175cb398811225b2d386088 385 Gene3D G3DSA:3.40.50.2000 172 357 2.3E-78 T 01-11-2018 MLA2C4_19330 bc49c9b7b175cb398811225b2d386088 385 Pfam PF13439 Glycosyltransferase Family 4 25 176 9.7E-17 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MLA2C4_19330 bc49c9b7b175cb398811225b2d386088 385 Gene3D G3DSA:3.40.50.2000 27 370 2.3E-78 T 01-11-2018 MLA2C4_18560 16b799505ddf1e73c500037174567239 1120 SUPERFAMILY SSF52490 5 166 2.22E-7 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MLA2C4_18560 16b799505ddf1e73c500037174567239 1120 Pfam PF13809 Tubulin like 8 345 1.5E-74 T 01-11-2018 IPR025904 Tubulin-like MLA2C4_18560 16b799505ddf1e73c500037174567239 1120 Gene3D G3DSA:3.40.50.1440 8 218 4.6E-11 T 01-11-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MLA2C4_06955 3cd6dde24be7639bfb68194668aa9141 264 Pfam PF03741 Integral membrane protein TerC family 16 208 6.2E-52 T 01-11-2018 IPR005496 Integral membrane protein TerC GO:0016021 MLA2C4_06955 3cd6dde24be7639bfb68194668aa9141 264 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 249 1.8E-92 T 01-11-2018 IPR022493 Integral membrane YkoY MLA2C4_06955 3cd6dde24be7639bfb68194668aa9141 264 SUPERFAMILY SSF103473 11 246 1.19E-7 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_06955 3cd6dde24be7639bfb68194668aa9141 264 Gene3D G3DSA:1.20.1250.20 5 249 2.8E-7 T 01-11-2018 MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.2E-18 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 SUPERFAMILY SSF46689 6 66 3.3E-19 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 Gene3D G3DSA:1.10.357.10 2 204 1.6E-59 T 01-11-2018 MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 SUPERFAMILY SSF48498 84 196 2.67E-9 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-10 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_13230 fe7bc8389441162b2608c8601dfeffdd 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-10 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 Pfam PF00107 Zinc-binding dehydrogenase 182 309 4.0E-29 T 01-11-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 Gene3D G3DSA:3.40.50.720 159 295 4.0E-114 T 01-11-2018 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 SMART SM00829 8 347 5.7E-6 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 68 82 - T 01-11-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 Gene3D G3DSA:3.90.180.10 9 334 4.0E-114 T 01-11-2018 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 141 1.1E-35 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 3.6E-6 T 01-11-2018 IPR027399 Alcohol dehydrogenase GroES-associated MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 SUPERFAMILY SSF50129 1 181 1.54E-58 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_03555 467d390c3585b41592860e79bc98b549 350 SUPERFAMILY SSF51735 146 313 6.97E-43 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_14725 dee55aeed6ad1dd7944a2763ae1c29c0 146 Gene3D G3DSA:3.90.79.10 2 144 5.8E-23 T 01-11-2018 MLA2C4_14725 dee55aeed6ad1dd7944a2763ae1c29c0 146 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_14725 dee55aeed6ad1dd7944a2763ae1c29c0 146 SUPERFAMILY SSF55811 3 125 8.8E-20 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_14725 dee55aeed6ad1dd7944a2763ae1c29c0 146 Pfam PF00293 NUDIX domain 8 121 1.1E-10 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_14725 dee55aeed6ad1dd7944a2763ae1c29c0 146 PRINTS PR00502 NUDIX hydrolase family signature 45 60 4.9E-5 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_14725 dee55aeed6ad1dd7944a2763ae1c29c0 146 PRINTS PR00502 NUDIX hydrolase family signature 31 45 4.9E-5 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_16290 549ccbea374a117a40a21cb0cc83ba49 144 SUPERFAMILY SSF47240 10 139 3.77E-29 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_16290 549ccbea374a117a40a21cb0cc83ba49 144 Gene3D G3DSA:1.20.5.420 93 138 1.6E-9 T 01-11-2018 MLA2C4_16290 549ccbea374a117a40a21cb0cc83ba49 144 Pfam PF02915 Rubrerythrin 92 140 3.5E-5 T 01-11-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 MLA2C4_16290 549ccbea374a117a40a21cb0cc83ba49 144 Gene3D G3DSA:1.20.1260.10 9 92 5.9E-7 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_26635 4ab3c6171b838c6e3faa80b8f575378f 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 8.0E-18 T 01-11-2018 IPR012452 Protein of unknown function DUF1657 MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 SUPERFAMILY SSF55031 178 283 1.27E-23 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 Pfam PF07687 Peptidase dimerisation domain 182 271 1.2E-9 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 Gene3D G3DSA:3.40.630.10 26 370 4.7E-136 T 01-11-2018 MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 350 1.0E-70 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 Gene3D G3DSA:3.30.70.360 175 292 4.7E-136 T 01-11-2018 MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 SUPERFAMILY SSF53187 11 384 1.82E-59 T 01-11-2018 MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 PIRSF PIRSF037226 3 401 8.9E-177 T 01-11-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted MLA2C4_16815 4d9cefe8f821cd6b7cb995260c7ad11f 401 Pfam PF01546 Peptidase family M20/M25/M40 89 354 9.3E-9 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PRINTS PR00069 Aldo-keto reductase signature 157 186 4.0E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PRINTS PR00069 Aldo-keto reductase signature 195 219 4.0E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.0E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.0E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PRINTS PR00069 Aldo-keto reductase signature 123 140 4.0E-52 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 SUPERFAMILY SSF51430 5 266 1.31E-95 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PIRSF PIRSF000097 113 273 2.4E-55 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 PIRSF PIRSF000097 2 116 8.5E-44 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 Gene3D G3DSA:3.20.20.100 1 274 5.2E-123 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 Pfam PF00248 Aldo/keto reductase family 24 192 1.9E-40 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 Pfam PF00248 Aldo/keto reductase family 200 259 4.1E-8 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_21445 1c4c998903f76541a604c00905713c09 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 01-11-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MLA2C4_20090 e8b4fd42a7bab738b66bda14ed8e2e08 90 SUPERFAMILY SSF54565 2 86 2.62E-35 T 01-11-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20090 e8b4fd42a7bab738b66bda14ed8e2e08 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.0E-35 T 01-11-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20090 e8b4fd42a7bab738b66bda14ed8e2e08 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 01-11-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_20090 e8b4fd42a7bab738b66bda14ed8e2e08 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.217 T 01-11-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20090 e8b4fd42a7bab738b66bda14ed8e2e08 90 Pfam PF00886 Ribosomal protein S16 9 67 1.2E-26 T 01-11-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_20090 e8b4fd42a7bab738b66bda14ed8e2e08 90 Gene3D G3DSA:3.30.1320.10 1 90 1.4E-37 T 01-11-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_23015 9d6b3b10b4dc7b93abf9e25d8f57e0d6 215 Gene3D G3DSA:3.30.240.20 158 215 2.8E-13 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_23015 9d6b3b10b4dc7b93abf9e25d8f57e0d6 215 Pfam PF04239 Protein of unknown function (DUF421) 88 193 1.1E-35 T 01-11-2018 IPR007353 Protein of unknown function DUF421 MLA2C4_23015 9d6b3b10b4dc7b93abf9e25d8f57e0d6 215 Gene3D G3DSA:3.30.240.20 80 153 1.4E-27 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 SUPERFAMILY SSF63380 1 89 4.93E-27 T 01-11-2018 IPR017938 Riboflavin synthase-like beta-barrel MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 Gene3D G3DSA:2.40.30.20 1 88 3.7E-32 T 01-11-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 3.3E-77 T 01-11-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 Pfam PF00677 Lumazine binding domain 3 86 2.8E-24 T 01-11-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 Pfam PF00677 Lumazine binding domain 99 183 2.3E-20 T 01-11-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 PIRSF PIRSF000498 1 209 1.0E-75 T 01-11-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 Gene3D G3DSA:2.40.30.20 101 202 3.0E-31 T 01-11-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MLA2C4_21515 5977930b4cb80532efafe0f7d5a02113 214 SUPERFAMILY SSF63380 92 196 4.93E-31 T 01-11-2018 IPR017938 Riboflavin synthase-like beta-barrel MLA2C4_04190 4882f55bc1db86b055a28c077ccfb3ef 542 SUPERFAMILY SSF53041 48 194 3.01E-21 T 01-11-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MLA2C4_04190 4882f55bc1db86b055a28c077ccfb3ef 542 Pfam PF07508 Recombinase 218 316 6.6E-15 T 01-11-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 MLA2C4_04190 4882f55bc1db86b055a28c077ccfb3ef 542 Gene3D G3DSA:3.40.50.1390 46 176 1.4E-16 T 01-11-2018 MLA2C4_04190 4882f55bc1db86b055a28c077ccfb3ef 542 Gene3D G3DSA:1.10.10.2600 178 319 2.6E-12 T 01-11-2018 IPR038109 DNA-binding recombinase domain superfamily MLA2C4_04190 4882f55bc1db86b055a28c077ccfb3ef 542 SMART SM00857 49 194 1.3E-26 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_04190 4882f55bc1db86b055a28c077ccfb3ef 542 Pfam PF00239 Resolvase, N terminal domain 50 194 2.6E-23 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 PIRSF PIRSF000368 1 150 8.6E-55 T 01-11-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 SUPERFAMILY SSF102114 22 101 6.67E-11 T 01-11-2018 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 149 1.0E-49 T 01-11-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 Pfam PF13353 4Fe-4S single cluster domain 12 146 2.0E-37 T 01-11-2018 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 Gene3D G3DSA:3.20.20.70 1 150 3.1E-36 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 Pfam PF04055 Radical SAM superfamily 20 118 2.1E-10 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_18705 f5ee91af6913a5f18dea59ee256ea1de 150 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 01-11-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 MLA2C4_00680 9449923bc88e8a1500a28c380f65608d 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 38.224 T 01-11-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00680 9449923bc88e8a1500a28c380f65608d 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 6.9E-84 T 01-11-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00680 9449923bc88e8a1500a28c380f65608d 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 7.6E-74 T 01-11-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MLA2C4_00680 9449923bc88e8a1500a28c380f65608d 207 SUPERFAMILY SSF52166 1 206 4.71E-86 T 01-11-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00680 9449923bc88e8a1500a28c380f65608d 207 Gene3D G3DSA:3.40.1370.10 2 207 2.2E-85 T 01-11-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_27330 d69c0f238782bf8e7990db638dfeb0a3 90 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 1.2E-45 T 01-11-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID MLA2C4_27330 d69c0f238782bf8e7990db638dfeb0a3 90 Pfam PF12116 Stage III sporulation protein D 2 82 2.7E-41 T 01-11-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID MLA2C4_27330 d69c0f238782bf8e7990db638dfeb0a3 90 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 01-11-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MLA2C4_27330 d69c0f238782bf8e7990db638dfeb0a3 90 Gene3D G3DSA:1.10.10.60 1 90 6.8E-43 T 01-11-2018 MLA2C4_00250 d984a6c4fcf36bb50e61e3d9e767fbe6 86 Pfam PF06257 Biofilm formation stimulator VEG 4 74 1.1E-29 T 01-11-2018 IPR009366 Protein Veg GO:0006355 MLA2C4_00250 d984a6c4fcf36bb50e61e3d9e767fbe6 86 PIRSF PIRSF037257 1 85 1.1E-35 T 01-11-2018 IPR009366 Protein Veg GO:0006355 MLA2C4_00250 d984a6c4fcf36bb50e61e3d9e767fbe6 86 Gene3D G3DSA:2.30.30.100 1 78 1.4E-25 T 01-11-2018 MLA2C4_09315 e8b6a35d537905b2a0f5960f0f890d85 270 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 17 236 2.2E-86 T 01-11-2018 IPR022488 Polyphosphate kinase-2-related MLA2C4_09315 e8b6a35d537905b2a0f5960f0f890d85 270 PIRSF PIRSF028756 2 265 1.1E-77 T 01-11-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 MLA2C4_09315 e8b6a35d537905b2a0f5960f0f890d85 270 Gene3D G3DSA:3.40.50.300 1 239 1.9E-98 T 01-11-2018 MLA2C4_09315 e8b6a35d537905b2a0f5960f0f890d85 270 SUPERFAMILY SSF52540 48 241 1.3E-26 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25865 12e47fcd26e41680a563f9fe1bb66836 184 Gene3D G3DSA:3.40.50.1240 1 175 1.9E-23 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_25865 12e47fcd26e41680a563f9fe1bb66836 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 13 170 3.8E-18 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_25865 12e47fcd26e41680a563f9fe1bb66836 184 SUPERFAMILY SSF53254 1 174 1.48E-27 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_24670 28106166bba4769cd91aab81909967ff 619 Pfam PF02687 FtsX-like permease family 84 179 1.7E-9 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_24670 28106166bba4769cd91aab81909967ff 619 PIRSF PIRSF018968 1 617 9.2E-61 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 Gene3D G3DSA:3.90.20.20 1 131 1.1E-25 T 01-11-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 Pfam PF01025 GrpE 25 188 6.2E-55 T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 PRINTS PR00773 GrpE protein signature 58 74 1.3E-30 T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 PRINTS PR00773 GrpE protein signature 86 101 1.3E-30 T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 PRINTS PR00773 GrpE protein signature 140 155 1.3E-30 T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 PRINTS PR00773 GrpE protein signature 167 186 1.3E-30 T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 SUPERFAMILY SSF58014 38 132 9.02E-26 T 01-11-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 SUPERFAMILY SSF51064 133 188 5.36E-19 T 01-11-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 ProSitePatterns PS01071 grpE protein signature. 143 186 - T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 Gene3D G3DSA:2.30.22.10 132 188 3.4E-25 T 01-11-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MLA2C4_22535 d5b196c263938b496fd536a4ad22347d 188 Hamap MF_01151 Protein GrpE [grpE]. 2 188 21.302 T 01-11-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 404 568 1.9E-49 T 01-11-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 86 133 6.4E-12 T 01-11-2018 IPR011096 FTP domain MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Gene3D G3DSA:2.60.40.10 666 742 8.9E-31 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Gene3D G3DSA:2.60.40.10 749 824 4.3E-23 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Gene3D G3DSA:2.60.40.10 583 657 8.8E-26 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 SUPERFAMILY SSF55486 248 568 2.2E-66 T 01-11-2018 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Gene3D G3DSA:3.10.170.10 247 405 1.4E-35 T 01-11-2018 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Pfam PF16403 Domain of unknown function (DUF5011) 673 739 2.9E-15 T 01-11-2018 IPR032179 Domain of unknown function DUF5011 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Pfam PF16403 Domain of unknown function (DUF5011) 755 817 3.7E-13 T 01-11-2018 IPR032179 Domain of unknown function DUF5011 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Pfam PF16403 Domain of unknown function (DUF5011) 591 656 4.8E-15 T 01-11-2018 IPR032179 Domain of unknown function DUF5011 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 854 887 1.4E-4 T 01-11-2018 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 249 401 3.4E-31 T 01-11-2018 IPR013856 Peptidase M4 domain GO:0004222 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 Gene3D G3DSA:1.10.390.10 406 568 7.8E-47 T 01-11-2018 IPR027268 Peptidase M4/M1, CTD superfamily MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 392 408 1.0E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 483 499 1.0E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 363 383 1.0E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_13565 926e79f8d1a82836e2c4816105bdd9a4 888 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 413 424 1.0E-14 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_07900 f63c9c405a496de4ae6de7fc3975fc30 203 PIRSF PIRSF036710 1 203 2.0E-93 T 01-11-2018 IPR014617 Predicted membrane protein, Bacillus YphA type MLA2C4_18850 c694247c8c55997316b709dc6765df91 147 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.8E-9 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_18850 c694247c8c55997316b709dc6765df91 147 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.8E-9 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_18850 c694247c8c55997316b709dc6765df91 147 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_18850 c694247c8c55997316b709dc6765df91 147 Gene3D G3DSA:3.90.79.10 6 146 8.6E-44 T 01-11-2018 MLA2C4_18850 c694247c8c55997316b709dc6765df91 147 Pfam PF00293 NUDIX domain 7 122 4.2E-19 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_18850 c694247c8c55997316b709dc6765df91 147 SUPERFAMILY SSF55811 9 126 1.49E-25 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-39 T 01-11-2018 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 Gene3D G3DSA:1.10.287.10 2 89 2.3E-37 T 01-11-2018 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.161 T 01-11-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 SUPERFAMILY SSF47060 3 89 1.44E-36 T 01-11-2018 IPR009068 S15/NS1, RNA-binding MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 01-11-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 Pfam PF00312 Ribosomal protein S15 8 88 7.0E-38 T 01-11-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 SMART SM01387 8 88 2.1E-52 T 01-11-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_19910 e18d850046a6aade4438a2c3be2ebd28 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 3.1E-42 T 01-11-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_18950 899a50dc96b9435630e4e69def46bb23 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 30 359 1.9E-89 T 01-11-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MLA2C4_18950 899a50dc96b9435630e4e69def46bb23 375 Gene3D G3DSA:3.20.20.70 21 373 6.2E-118 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_18950 899a50dc96b9435630e4e69def46bb23 375 SUPERFAMILY SSF51395 25 367 1.32E-110 T 01-11-2018 MLA2C4_26575 3768da9876c48ba3179f5180b0bcb488 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 01-11-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26575 3768da9876c48ba3179f5180b0bcb488 251 Gene3D G3DSA:3.20.20.70 2 250 1.2E-101 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_26575 3768da9876c48ba3179f5180b0bcb488 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 59.432 T 01-11-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26575 3768da9876c48ba3179f5180b0bcb488 251 Pfam PF00121 Triosephosphate isomerase 5 246 1.7E-91 T 01-11-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26575 3768da9876c48ba3179f5180b0bcb488 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 8.1E-61 T 01-11-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_26575 3768da9876c48ba3179f5180b0bcb488 251 SUPERFAMILY SSF51351 1 249 1.83E-92 T 01-11-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MLA2C4_28250 9f6914065297f2675401982a6c5436c2 473 Pfam PF11997 Domain of unknown function (DUF3492) 1 255 6.7E-72 T 01-11-2018 IPR022622 Domain of unknown function DUF3492 MLA2C4_28250 9f6914065297f2675401982a6c5436c2 473 Pfam PF00534 Glycosyl transferases group 1 276 445 3.9E-28 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_28250 9f6914065297f2675401982a6c5436c2 473 SUPERFAMILY SSF53756 2 464 4.93E-59 T 01-11-2018 MLA2C4_28250 9f6914065297f2675401982a6c5436c2 473 Gene3D G3DSA:3.40.50.2000 272 450 2.9E-36 T 01-11-2018 MLA2C4_19920 d18d60079de0ee5b838420cde837bdb5 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 299 19.024 T 01-11-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_19920 d18d60079de0ee5b838420cde837bdb5 307 Gene3D G3DSA:3.30.2350.10 1 244 3.2E-90 T 01-11-2018 MLA2C4_19920 d18d60079de0ee5b838420cde837bdb5 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 4.9E-10 T 01-11-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MLA2C4_19920 d18d60079de0ee5b838420cde837bdb5 307 SUPERFAMILY SSF55120 1 221 6.08E-79 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_19920 d18d60079de0ee5b838420cde837bdb5 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 5.8E-82 T 01-11-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_19920 d18d60079de0ee5b838420cde837bdb5 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 5.7E-57 T 01-11-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MLA2C4_13710 ce9d9b0332e285cd30c97bdb1a132b98 266 Gene3D G3DSA:3.40.50.300 8 255 3.2E-57 T 01-11-2018 MLA2C4_13710 ce9d9b0332e285cd30c97bdb1a132b98 266 SUPERFAMILY SSF52540 18 238 1.2E-53 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13710 ce9d9b0332e285cd30c97bdb1a132b98 266 SMART SM00382 44 227 6.0E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13710 ce9d9b0332e285cd30c97bdb1a132b98 266 Pfam PF00005 ABC transporter 36 178 3.9E-22 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18770 68f3a6d65227b045d670568bbeb23fd0 67 Pfam PF00550 Phosphopantetheine attachment site 21 57 5.2E-6 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_18770 68f3a6d65227b045d670568bbeb23fd0 67 SUPERFAMILY SSF47336 11 65 4.84E-10 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_18770 68f3a6d65227b045d670568bbeb23fd0 67 Gene3D G3DSA:1.10.1200.10 3 67 8.0E-11 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 SUPERFAMILY SSF51905 2 458 2.1E-43 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 Pfam PF01593 Flavin containing amine oxidoreductase 13 458 6.0E-44 T 01-11-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 Gene3D G3DSA:1.10.3110.10 106 199 1.2E-113 T 01-11-2018 MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 Gene3D G3DSA:3.50.50.60 5 449 1.2E-113 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 SUPERFAMILY SSF54373 300 407 2.35E-19 T 01-11-2018 MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 459 8.0E-83 T 01-11-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MLA2C4_12440 1e64528c196cef41ff09ce3e17a8c23e 466 Gene3D G3DSA:3.90.660.20 40 407 1.2E-113 T 01-11-2018 MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 356 477 8.8E-12 T 01-11-2018 IPR000014 PAS domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 Gene3D G3DSA:3.20.20.450 656 905 2.9E-94 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 Gene3D G3DSA:3.30.450.20 341 480 3.8E-16 T 01-11-2018 MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 Pfam PF13426 PAS domain 368 469 6.2E-8 T 01-11-2018 IPR000014 PAS domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 SMART SM00091 358 424 5.9E-7 T 01-11-2018 IPR000014 PAS domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 Pfam PF00563 EAL domain 658 893 1.2E-68 T 01-11-2018 IPR001633 EAL domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 SMART SM00052 652 898 1.3E-110 T 01-11-2018 IPR001633 EAL domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 Gene3D G3DSA:3.30.70.270 481 655 2.1E-55 T 01-11-2018 MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 480 641 2.0E-38 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 Pfam PF00990 Diguanylate cyclase, GGDEF domain 482 637 1.6E-46 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 SMART SM00267 471 642 7.3E-64 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 SUPERFAMILY SSF55073 488 644 1.96E-48 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 SUPERFAMILY SSF55785 350 469 1.13E-12 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_18255 b3dcc4b4c897292167e478b81ef96e82 906 SUPERFAMILY SSF141868 657 904 7.98E-86 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_07570 e046345488f58ac3e108955c9a9228a0 172 Gene3D G3DSA:2.40.380.10 67 167 6.0E-10 T 01-11-2018 IPR035930 FomD-like superfamily MLA2C4_07570 e046345488f58ac3e108955c9a9228a0 172 SUPERFAMILY SSF159234 1 166 1.31E-37 T 01-11-2018 IPR035930 FomD-like superfamily MLA2C4_07570 e046345488f58ac3e108955c9a9228a0 172 Pfam PF04167 Protein of unknown function (DUF402) 59 125 7.4E-17 T 01-11-2018 IPR007295 Domain of unknown function DUF402 MLA2C4_08040 e8ca86be1e83785313f296cfe5b09b31 213 SMART SM00987 25 204 1.7E-21 T 01-11-2018 MLA2C4_08040 e8ca86be1e83785313f296cfe5b09b31 213 Gene3D G3DSA:3.40.470.10 6 212 8.2E-49 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_08040 e8ca86be1e83785313f296cfe5b09b31 213 SMART SM00986 25 204 1.7E-21 T 01-11-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_08040 e8ca86be1e83785313f296cfe5b09b31 213 SUPERFAMILY SSF52141 10 210 2.35E-40 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_08040 e8ca86be1e83785313f296cfe5b09b31 213 Pfam PF03167 Uracil DNA glycosylase superfamily 26 203 6.2E-41 T 01-11-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 Gene3D G3DSA:3.20.20.80 1 109 9.1E-51 T 01-11-2018 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 SUPERFAMILY SSF51445 3 473 9.16E-157 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 SUPERFAMILY SSF51011 476 553 2.49E-17 T 01-11-2018 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 Gene3D G3DSA:3.20.20.80 171 476 4.1E-118 T 01-11-2018 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 Pfam PF00128 Alpha amylase, catalytic domain 28 373 1.4E-116 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 Gene3D G3DSA:2.60.40.1180 477 554 8.3E-22 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 Gene3D G3DSA:3.90.400.10 110 170 6.6E-35 T 01-11-2018 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 SMART SM00642 13 415 4.9E-164 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_02190 3bac9b8e9c310e47c7a4c5abe1516070 554 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 548 1.6E-8 T 01-11-2018 IPR032091 Maltogenic Amylase, C-terminal MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 Gene3D G3DSA:1.10.1790.10 64 167 1.6E-36 T 01-11-2018 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 Gene3D G3DSA:2.30.24.10 1 55 7.3E-25 T 01-11-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 SUPERFAMILY SSF63520 58 166 1.57E-29 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 SMART SM01061 1 59 4.5E-30 T 01-11-2018 IPR004341 CAT RNA-binding domain GO:0003723 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 Gene3D G3DSA:1.10.1790.10 169 278 3.5E-40 T 01-11-2018 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 SUPERFAMILY SSF63520 172 274 1.31E-28 T 01-11-2018 IPR036634 PRD domain superfamily GO:0006355 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 Pfam PF00874 PRD domain 181 273 5.5E-19 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 Pfam PF00874 PRD domain 76 163 6.7E-22 T 01-11-2018 IPR011608 PRD domain GO:0006355 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 Pfam PF03123 CAT RNA binding domain 1 55 5.6E-25 T 01-11-2018 IPR004341 CAT RNA-binding domain GO:0003723 MLA2C4_05100 ab33325517bf103e030056ee1af32fbf 282 SUPERFAMILY SSF50151 1 53 1.31E-18 T 01-11-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 MLA2C4_01975 c5691baea4d562c436c7fc26867fe065 329 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 01-11-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MLA2C4_01975 c5691baea4d562c436c7fc26867fe065 329 SUPERFAMILY SSF51395 13 319 9.53E-58 T 01-11-2018 MLA2C4_01975 c5691baea4d562c436c7fc26867fe065 329 PIRSF PIRSF006621 1 328 4.4E-82 T 01-11-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MLA2C4_01975 c5691baea4d562c436c7fc26867fe065 329 Pfam PF01207 Dihydrouridine synthase (Dus) 15 318 1.5E-48 T 01-11-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MLA2C4_01975 c5691baea4d562c436c7fc26867fe065 329 Gene3D G3DSA:3.20.20.70 13 247 4.3E-60 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_14570 f93f859ddac32721904527b4b04ccc81 165 SUPERFAMILY SSF55729 8 151 2.98E-14 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14570 f93f859ddac32721904527b4b04ccc81 165 Pfam PF00583 Acetyltransferase (GNAT) family 33 142 4.7E-9 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14570 f93f859ddac32721904527b4b04ccc81 165 Gene3D G3DSA:3.40.630.30 2 163 6.3E-16 T 01-11-2018 MLA2C4_14340 448a1141fba133b6ec10db8b83eb3d80 157 Gene3D G3DSA:3.40.630.30 1 156 5.7E-18 T 01-11-2018 MLA2C4_14340 448a1141fba133b6ec10db8b83eb3d80 157 SUPERFAMILY SSF55729 1 143 7.5E-20 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14340 448a1141fba133b6ec10db8b83eb3d80 157 Pfam PF13673 Acetyltransferase (GNAT) domain 41 145 3.1E-9 T 01-11-2018 IPR000182 GNAT domain MLA2C4_16745 0c87fba67f12390e2cd85b060d9f8977 199 Pfam PF01965 DJ-1/PfpI family 1 174 1.8E-24 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_16745 0c87fba67f12390e2cd85b060d9f8977 199 SUPERFAMILY SSF52317 1 191 5.18E-36 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_16745 0c87fba67f12390e2cd85b060d9f8977 199 Gene3D G3DSA:3.40.50.880 1 197 7.1E-50 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 SUPERFAMILY SSF52540 309 754 2.02E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Gene3D G3DSA:3.40.50.300 556 701 6.7E-46 T 01-11-2018 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Gene3D G3DSA:3.40.50.300 282 429 1.8E-29 T 01-11-2018 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1171 0.0 T 01-11-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Pfam PF13361 UvrD-like helicase C-terminal domain 300 670 5.3E-10 T 01-11-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1170 67.286 T 01-11-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Gene3D G3DSA:3.40.50.300 1 133 4.6E-34 T 01-11-2018 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Gene3D G3DSA:3.40.50.300 135 278 4.5E-33 T 01-11-2018 MLA2C4_05990 0aee441066dfaf93a71ee479934c2105 1171 Pfam PF12705 PD-(D/E)XK nuclease superfamily 795 1139 4.8E-55 T 01-11-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MLA2C4_14205 3a247278b3799b58a9b78787b4db610f 266 SUPERFAMILY SSF55729 79 258 2.4E-19 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14205 3a247278b3799b58a9b78787b4db610f 266 Gene3D G3DSA:3.40.630.30 45 258 3.6E-24 T 01-11-2018 MLA2C4_14205 3a247278b3799b58a9b78787b4db610f 266 Pfam PF13673 Acetyltransferase (GNAT) domain 149 261 3.9E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 Gene3D G3DSA:3.30.499.20 3 283 5.2E-101 T 01-11-2018 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 456 57.291 T 01-11-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 SUPERFAMILY SSF53732 2 454 1.44E-163 T 01-11-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 Pfam PF00330 Aconitase family (aconitate hydratase) 7 447 2.8E-154 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 ProSitePatterns PS00450 Aconitase family signature 1. 329 345 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 ProSitePatterns PS01244 Aconitase family signature 2. 389 402 - T 01-11-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 194 207 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 118 131 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 132 147 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 333 344 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 107 115 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 208 221 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 389 402 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 81 94 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 PRINTS PR00415 Aconitase family signature 283 297 1.3E-44 T 01-11-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 Gene3D G3DSA:3.30.499.10 317 462 5.0E-50 T 01-11-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MLA2C4_07415 db59e39e770388ac5d7b0a4684e46e79 464 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 454 1.4E-214 T 01-11-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MLA2C4_00220 5acdf31ff9e6bcdd39bafe3f6143e986 94 SMART SM00966 8 51 6.6E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_00220 5acdf31ff9e6bcdd39bafe3f6143e986 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 4.6E-11 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_00220 5acdf31ff9e6bcdd39bafe3f6143e986 94 SUPERFAMILY SSF89447 1 52 1.23E-16 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily MLA2C4_00220 5acdf31ff9e6bcdd39bafe3f6143e986 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 8.8E-12 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_00220 5acdf31ff9e6bcdd39bafe3f6143e986 94 Gene3D G3DSA:2.10.260.10 1 51 1.4E-26 T 01-11-2018 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 Gene3D G3DSA:1.10.3860.10 1 397 5.1E-81 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 SUPERFAMILY SSF118215 7 392 6.93E-84 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 Pfam PF00375 Sodium:dicarboxylate symporter family 10 392 8.8E-96 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 PRINTS PR00173 Glutamate-aspartate symporter signature 182 201 1.2E-15 T 01-11-2018 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 PRINTS PR00173 Glutamate-aspartate symporter signature 135 157 1.2E-15 T 01-11-2018 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.2E-15 T 01-11-2018 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 PRINTS PR00173 Glutamate-aspartate symporter signature 284 310 1.2E-15 T 01-11-2018 MLA2C4_26985 338e051f54c315ced97f1bf343b7ca11 405 PRINTS PR00173 Glutamate-aspartate symporter signature 347 367 1.2E-15 T 01-11-2018 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 Gene3D G3DSA:4.10.520.10 15 104 1.4E-41 T 01-11-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 Pfam PF00216 Bacterial DNA-binding protein 15 104 3.4E-38 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 SMART SM00411 15 104 8.2E-53 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 PRINTS PR01727 Prokaryotic integration host factor signature 88 102 2.2E-22 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 PRINTS PR01727 Prokaryotic integration host factor signature 54 69 2.2E-22 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 PRINTS PR01727 Prokaryotic integration host factor signature 72 85 2.2E-22 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 SUPERFAMILY SSF47729 15 104 7.51E-36 T 01-11-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MLA2C4_07945 1dfd26f5d1560f03cc9a37b50cbf71b3 104 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 60 79 - T 01-11-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MLA2C4_27775 4830d55f897b4ce7300fb328d77a55c1 145 Pfam PF09148 Domain of unknown function (DUF1934) 13 139 1.2E-28 T 01-11-2018 IPR015231 Protein of unknown function DUF1934 MLA2C4_27775 4830d55f897b4ce7300fb328d77a55c1 145 SUPERFAMILY SSF50814 7 143 2.08E-37 T 01-11-2018 IPR012674 Calycin MLA2C4_27775 4830d55f897b4ce7300fb328d77a55c1 145 Gene3D G3DSA:2.40.128.20 2 145 1.3E-41 T 01-11-2018 IPR012674 Calycin MLA2C4_04755 2ee129524fa3ceca9a7eae1d7df0c706 518 SUPERFAMILY SSF56801 3 514 1.27E-147 T 01-11-2018 MLA2C4_04755 2ee129524fa3ceca9a7eae1d7df0c706 518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_04755 2ee129524fa3ceca9a7eae1d7df0c706 518 Gene3D G3DSA:3.30.300.310 415 517 4.8E-34 T 01-11-2018 MLA2C4_04755 2ee129524fa3ceca9a7eae1d7df0c706 518 Pfam PF00501 AMP-binding enzyme 12 418 1.3E-99 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_04755 2ee129524fa3ceca9a7eae1d7df0c706 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 503 2.1E-20 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_04755 2ee129524fa3ceca9a7eae1d7df0c706 518 Gene3D G3DSA:3.40.50.12780 7 414 8.4E-113 T 01-11-2018 MLA2C4_09600 ada6b29d178e4af99df65e26966dc42b 402 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 54 231 2.9E-66 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_09600 ada6b29d178e4af99df65e26966dc42b 402 Gene3D G3DSA:1.20.1170.10 59 397 1.8E-121 T 01-11-2018 MLA2C4_09600 ada6b29d178e4af99df65e26966dc42b 402 SUPERFAMILY SSF58100 45 390 3.14E-97 T 01-11-2018 MLA2C4_19335 47c2ea484ed8a50d9ce99c02278b70d1 608 SUPERFAMILY SSF51735 276 539 4.81E-55 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_19335 47c2ea484ed8a50d9ce99c02278b70d1 608 Pfam PF13727 CoA-binding domain 76 233 6.5E-12 T 01-11-2018 MLA2C4_19335 47c2ea484ed8a50d9ce99c02278b70d1 608 Gene3D G3DSA:3.40.50.720 133 259 9.3E-36 T 01-11-2018 MLA2C4_19335 47c2ea484ed8a50d9ce99c02278b70d1 608 Pfam PF02719 Polysaccharide biosynthesis protein 278 561 8.2E-124 T 01-11-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MLA2C4_19335 47c2ea484ed8a50d9ce99c02278b70d1 608 Gene3D G3DSA:3.40.50.720 273 602 9.7E-119 T 01-11-2018 MLA2C4_19335 47c2ea484ed8a50d9ce99c02278b70d1 608 SUPERFAMILY SSF53335 99 302 9.47E-16 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_08210 1c6cbbcff016cbb5ea1efd5d5b375ea8 645 SUPERFAMILY SSF52540 53 622 6.89E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08210 1c6cbbcff016cbb5ea1efd5d5b375ea8 645 SMART SM00491 503 627 4.4E-8 T 01-11-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MLA2C4_08210 1c6cbbcff016cbb5ea1efd5d5b375ea8 645 Gene3D G3DSA:3.40.50.300 38 320 2.3E-28 T 01-11-2018 MLA2C4_08210 1c6cbbcff016cbb5ea1efd5d5b375ea8 645 Pfam PF13307 Helicase C-terminal domain 488 621 5.6E-25 T 01-11-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MLA2C4_08210 1c6cbbcff016cbb5ea1efd5d5b375ea8 645 Gene3D G3DSA:3.40.50.300 463 633 3.8E-27 T 01-11-2018 MLA2C4_02290 410c592b2f23160eff5c16a7daa0972c 437 PIRSF PIRSF004539 1 437 1.7E-192 T 01-11-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MLA2C4_02290 410c592b2f23160eff5c16a7daa0972c 437 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 369 1.6E-158 T 01-11-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MLA2C4_02290 410c592b2f23160eff5c16a7daa0972c 437 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 436 7.7E-173 T 01-11-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MLA2C4_22325 c49b9bf1f8a61e77236d1903b8c2c6ae 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 2.1E-18 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_22325 c49b9bf1f8a61e77236d1903b8c2c6ae 316 Gene3D G3DSA:1.10.3720.10 88 315 5.7E-35 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_22325 c49b9bf1f8a61e77236d1903b8c2c6ae 316 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 32 312 2.6E-80 T 01-11-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MLA2C4_22325 c49b9bf1f8a61e77236d1903b8c2c6ae 316 SUPERFAMILY SSF161098 35 308 1.44E-34 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 403 565 2.0E-64 T 01-11-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Gene3D G3DSA:3.10.450.40 142 225 1.0E-5 T 01-11-2018 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 SUPERFAMILY SSF55486 256 565 2.2E-104 T 01-11-2018 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 84 134 4.0E-14 T 01-11-2018 IPR011096 FTP domain MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Gene3D G3DSA:3.10.450.490 62 141 5.9E-6 T 01-11-2018 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Gene3D G3DSA:1.10.390.10 405 565 2.5E-74 T 01-11-2018 IPR027268 Peptidase M4/M1, CTD superfamily MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 257 400 2.1E-52 T 01-11-2018 IPR013856 Peptidase M4 domain GO:0004222 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 355 375 4.9E-31 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 391 407 4.9E-31 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 480 496 4.9E-31 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 412 423 4.9E-31 T 01-11-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Pfam PF03413 Peptidase propeptide and YPEB domain 151 220 1.4E-8 T 01-11-2018 IPR025711 PepSY domain MLA2C4_03170 835d519ebc986e6d320ce76de95d67c6 566 Gene3D G3DSA:3.10.170.10 255 404 2.7E-66 T 01-11-2018 MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 243 2.6E-23 T 01-11-2018 IPR005135 Endonuclease/exonuclease/phosphatase MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 SUPERFAMILY SSF56219 2 251 7.33E-81 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 Gene3D G3DSA:3.60.10.10 1 251 1.3E-98 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 01-11-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 3.5E-102 T 01-11-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 250 1.1E-100 T 01-11-2018 MLA2C4_19530 57811dc6a92b1cd7d2c40cf82bc5b76f 252 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 211 222 - T 01-11-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 MLA2C4_15110 f4837fd4ab84ad95ff85e4efe3e80dbb 76 SUPERFAMILY SSF46785 14 75 8.73E-7 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 Pfam PF00589 Phage integrase family 111 285 1.9E-51 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 299 1.1E-101 T 01-11-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 90 1.1E-23 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 SUPERFAMILY SSF56349 3 293 9.71E-60 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 Gene3D G3DSA:1.10.150.130 3 98 1.7E-26 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 299 57.495 T 01-11-2018 IPR023009 Tyrosine recombinase XerC/XerD MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 9 299 1.5E-110 T 01-11-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 MLA2C4_20025 9f35720c85f862b599fb0d0c115e6898 299 Gene3D G3DSA:1.10.443.10 111 293 6.1E-63 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 SUPERFAMILY SSF54570 3 83 9.02E-35 T 01-11-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 8.0E-47 T 01-11-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.013 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 PIRSF PIRSF002144 1 92 3.7E-32 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 01-11-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.3E-25 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.3E-25 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.3E-25 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 Pfam PF00203 Ribosomal protein S19 3 83 4.0E-36 T 01-11-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00695 1905e41a7c02e04d00ea435ec0fe19c1 92 Gene3D G3DSA:3.30.860.10 1 92 1.3E-40 T 01-11-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 Pfam PF01165 Ribosomal protein S21 5 57 5.2E-21 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 9.0E-16 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 9.0E-16 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 9.0E-16 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 9.0E-16 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 1.6E-21 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 Gene3D G3DSA:1.20.5.1150 16 56 3.1E-18 T 01-11-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.633 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 1.0E-8 T 01-11-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_22505 26ae892bde23897c189a91b0a25be68e 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 01-11-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_17145 68b8003613b7cef75f8eb5846d980077 292 Pfam PF02517 CAAX protease self-immunity 152 247 9.3E-10 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_23565 bbf4859c0399cb0fb777c00680402813 238 Pfam PF12730 ABC-2 family transporter protein 5 148 2.6E-7 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_22275 455c05d45501b92c0586bb5dede00ed0 209 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 7.4E-33 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_22275 455c05d45501b92c0586bb5dede00ed0 209 SMART SM00849 12 192 4.9E-42 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_22275 455c05d45501b92c0586bb5dede00ed0 209 Gene3D G3DSA:3.60.15.10 1 209 5.4E-64 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_22275 455c05d45501b92c0586bb5dede00ed0 209 SUPERFAMILY SSF56281 1 209 2.88E-53 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21675 af42fd75affcffdcc55f46140512c383 233 Gene3D G3DSA:3.30.70.260 139 231 4.3E-15 T 01-11-2018 MLA2C4_21675 af42fd75affcffdcc55f46140512c383 233 Pfam PF02308 MgtC family 10 129 1.1E-36 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_21675 af42fd75affcffdcc55f46140512c383 233 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.2E-45 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_21675 af42fd75affcffdcc55f46140512c383 233 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.2E-45 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_21675 af42fd75affcffdcc55f46140512c383 233 PRINTS PR01837 MgtC/SapB protein signature 58 80 3.2E-45 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_21675 af42fd75affcffdcc55f46140512c383 233 PRINTS PR01837 MgtC/SapB protein signature 85 109 3.2E-45 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 SUPERFAMILY SSF53474 39 286 2.7E-56 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 Pfam PF00561 alpha/beta hydrolase fold 206 273 3.9E-7 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 Pfam PF00561 alpha/beta hydrolase fold 65 164 5.4E-23 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 Gene3D G3DSA:3.40.50.1820 32 290 6.1E-55 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 105 2.1E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 2.1E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_05470 789eada85cb5930d2ef443b65c60aeda 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 2.1E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_05595 761f36f5975a9365c1c3e22fa4db3e40 235 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 234 2.0E-117 T 01-11-2018 MLA2C4_05595 761f36f5975a9365c1c3e22fa4db3e40 235 Pfam PF12787 EcsC protein family 7 232 3.9E-77 T 01-11-2018 IPR024787 EcsC protein MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 90 103 1.2E-15 T 01-11-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 107 121 1.2E-15 T 01-11-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 135 1.2E-15 T 01-11-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 SUPERFAMILY SSF51230 84 160 2.62E-23 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 Gene3D G3DSA:2.40.50.100 83 160 1.6E-28 T 01-11-2018 MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 Pfam PF00364 Biotin-requiring enzyme 87 158 3.7E-22 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_21890 be78f9c4a18b3e3c3712709fc4ea152e 162 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 161 1.8E-53 T 01-11-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 SUPERFAMILY SSF52540 296 529 3.39E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 SUPERFAMILY SSF52540 2 255 1.49E-48 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 Gene3D G3DSA:3.40.50.300 1 280 2.7E-59 T 01-11-2018 MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 SMART SM00382 26 228 2.1E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 SMART SM00382 344 513 3.0 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 Pfam PF00005 ABC transporter 335 468 2.5E-15 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 Pfam PF12848 ABC transporter 224 300 1.8E-19 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 Gene3D G3DSA:3.40.50.300 287 541 8.2E-44 T 01-11-2018 MLA2C4_15535 10b60280fa6402627c7f95ffac0b6281 541 Pfam PF00005 ABC transporter 18 184 1.5E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_16260 5e737d8769ad146eded4729f6469a3c6 195 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 1.5E-18 T 01-11-2018 IPR000182 GNAT domain MLA2C4_16260 5e737d8769ad146eded4729f6469a3c6 195 Gene3D G3DSA:3.40.630.30 1 189 1.1E-43 T 01-11-2018 MLA2C4_16260 5e737d8769ad146eded4729f6469a3c6 195 SUPERFAMILY SSF55729 2 173 1.51E-38 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10280 26624089828b943242638940f69bedfb 487 Gene3D G3DSA:1.10.10.1620 442 487 3.4E-20 T 01-11-2018 MLA2C4_10280 26624089828b943242638940f69bedfb 487 Gene3D G3DSA:1.10.405.10 125 235 2.2E-96 T 01-11-2018 MLA2C4_10280 26624089828b943242638940f69bedfb 487 SUPERFAMILY SSF54373 326 436 1.18E-30 T 01-11-2018 MLA2C4_10280 26624089828b943242638940f69bedfb 487 SUPERFAMILY SSF51905 27 486 1.6E-59 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_10280 26624089828b943242638940f69bedfb 487 PRINTS PR00757 Flavin-containing amine oxidase signature 330 349 3.2E-8 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_10280 26624089828b943242638940f69bedfb 487 PRINTS PR00757 Flavin-containing amine oxidase signature 30 49 3.2E-8 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_10280 26624089828b943242638940f69bedfb 487 PRINTS PR00757 Flavin-containing amine oxidase signature 467 484 3.2E-8 T 01-11-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 MLA2C4_10280 26624089828b943242638940f69bedfb 487 Gene3D G3DSA:3.50.50.60 30 433 2.2E-96 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_10280 26624089828b943242638940f69bedfb 487 Gene3D G3DSA:3.90.660.10 6 425 2.2E-96 T 01-11-2018 MLA2C4_10280 26624089828b943242638940f69bedfb 487 Pfam PF01593 Flavin containing amine oxidoreductase 38 485 2.1E-77 T 01-11-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MLA2C4_02680 440f5894704075b5c90e42f25f08a5cb 270 Gene3D G3DSA:1.10.10.10 220 270 5.0E-11 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_02680 440f5894704075b5c90e42f25f08a5cb 270 Gene3D G3DSA:1.10.10.10 157 219 1.9E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_02680 440f5894704075b5c90e42f25f08a5cb 270 Gene3D G3DSA:1.10.10.2800 1 111 5.7E-33 T 01-11-2018 MLA2C4_02680 440f5894704075b5c90e42f25f08a5cb 270 Pfam PF02631 RecX family 88 210 5.9E-27 T 01-11-2018 IPR003783 Regulatory protein RecX GO:0006282 MLA2C4_02680 440f5894704075b5c90e42f25f08a5cb 270 Gene3D G3DSA:1.10.10.10 112 156 2.8E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_02680 440f5894704075b5c90e42f25f08a5cb 270 Hamap MF_01114 Regulatory protein RecX [recX]. 46 213 15.968 T 01-11-2018 IPR003783 Regulatory protein RecX GO:0006282 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 92 111 1.1E-44 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 72 92 1.1E-44 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 180 200 1.1E-44 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 225 250 1.1E-44 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 201 222 1.1E-44 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 53 72 1.1E-44 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 Pfam PF00813 FliP family 55 245 8.7E-57 T 01-11-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 173 185 1.9E-6 T 01-11-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 123 137 1.9E-6 T 01-11-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 111 123 1.9E-6 T 01-11-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MLA2C4_08705 3004ad96cd9d6a7b5a9bb2aa44246361 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 51 60 1.9E-6 T 01-11-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MLA2C4_21535 4efc758185a834957793a24167945057 332 Pfam PF04055 Radical SAM superfamily 70 226 3.4E-14 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_21535 4efc758185a834957793a24167945057 332 SMART SM00876 237 327 2.9E-35 T 01-11-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MLA2C4_21535 4efc758185a834957793a24167945057 332 SUPERFAMILY SSF102114 23 328 3.14E-73 T 01-11-2018 MLA2C4_21535 4efc758185a834957793a24167945057 332 Gene3D G3DSA:3.20.20.70 21 330 1.2E-107 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_21535 4efc758185a834957793a24167945057 332 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 237 326 1.6E-14 T 01-11-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MLA2C4_21535 4efc758185a834957793a24167945057 332 SMART SM00729 61 269 2.9E-34 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_21535 4efc758185a834957793a24167945057 332 PIRSF PIRSF001619 4 332 8.7E-125 T 01-11-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MLA2C4_21535 4efc758185a834957793a24167945057 332 TIGRFAM TIGR00433 bioB: biotin synthase 33 326 3.9E-121 T 01-11-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MLA2C4_21535 4efc758185a834957793a24167945057 332 Hamap MF_01694 Biotin synthase [bioB]. 21 328 40.466 T 01-11-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MLA2C4_16330 d71454c22c44dcf117407a5643649add 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 5.7E-23 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_16330 d71454c22c44dcf117407a5643649add 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_16330 d71454c22c44dcf117407a5643649add 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_16330 d71454c22c44dcf117407a5643649add 70 Gene3D G3DSA:1.10.8.910 10 70 1.5E-31 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_08965 ada4b8c028486626dff75be623aea3f3 219 SUPERFAMILY SSF53335 20 191 9.14E-15 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_08965 ada4b8c028486626dff75be623aea3f3 219 Pfam PF13578 Methyltransferase domain 45 161 2.4E-24 T 01-11-2018 MLA2C4_08965 ada4b8c028486626dff75be623aea3f3 219 Gene3D G3DSA:3.40.50.150 20 198 1.8E-17 T 01-11-2018 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 44.369 T 01-11-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 5.4E-107 T 01-11-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 Gene3D G3DSA:3.20.190.10 1 135 6.3E-41 T 01-11-2018 IPR035937 MutM-like, N-terminal MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 Gene3D G3DSA:1.10.8.50 136 275 7.8E-49 T 01-11-2018 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 SUPERFAMILY SSF46946 134 223 5.36E-29 T 01-11-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 6.6E-34 T 01-11-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 SMART SM00898 2 118 8.7E-51 T 01-11-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 01-11-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 SUPERFAMILY SSF57716 222 274 1.49E-17 T 01-11-2018 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 SUPERFAMILY SSF81624 2 139 1.44E-42 T 01-11-2018 IPR035937 MutM-like, N-terminal MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 Pfam PF06827 Zinc finger found in FPG and IleRS 246 275 2.4E-10 T 01-11-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 SMART SM01232 134 226 1.2E-44 T 01-11-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MLA2C4_23825 f39fbb6fca3710515a75a8db15c1a04a 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 224 1.0E-28 T 01-11-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MLA2C4_20135 ffe8bc68c99014fdb253a6fe49159828 330 SUPERFAMILY SSF53659 1 326 4.52E-106 T 01-11-2018 MLA2C4_20135 ffe8bc68c99014fdb253a6fe49159828 330 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 330 153.355 T 01-11-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MLA2C4_20135 ffe8bc68c99014fdb253a6fe49159828 330 PIRSF PIRSF002465 1 329 1.8E-130 T 01-11-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MLA2C4_20135 ffe8bc68c99014fdb253a6fe49159828 330 Pfam PF02504 Fatty acid synthesis protein 1 317 1.3E-127 T 01-11-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 MLA2C4_20135 ffe8bc68c99014fdb253a6fe49159828 330 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 326 8.6E-136 T 01-11-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MLA2C4_20135 ffe8bc68c99014fdb253a6fe49159828 330 Gene3D G3DSA:3.40.718.10 1 329 1.5E-138 T 01-11-2018 MLA2C4_09725 80521ed2a88f1c0d040e3ef0faa7d32d 206 Gene3D G3DSA:2.60.40.2230 25 168 4.3E-33 T 01-11-2018 IPR038507 YcnI-like superfamily MLA2C4_09725 80521ed2a88f1c0d040e3ef0faa7d32d 206 Pfam PF07987 Domain of unkown function (DUF1775) 28 148 9.2E-20 T 01-11-2018 IPR012533 YcnI-like MLA2C4_20470 2d451e22fd1f98e6fe983dbd1393434e 120 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 38 118 2.2E-24 T 01-11-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MLA2C4_20470 2d451e22fd1f98e6fe983dbd1393434e 120 Hamap MF_00910 Cell division protein FtsL [ftsL]. 38 120 13.453 T 01-11-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MLA2C4_20470 2d451e22fd1f98e6fe983dbd1393434e 120 Pfam PF04977 Septum formation initiator 45 111 4.9E-14 T 01-11-2018 IPR007060 Septum formation initiator FtsL/DivIC MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 Gene3D G3DSA:1.10.10.10 135 228 1.7E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 SMART SM00448 3 113 7.5E-42 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 2.8E-25 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 SMART SM00862 152 225 1.7E-23 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 Pfam PF00072 Response regulator receiver domain 5 112 3.6E-29 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 Gene3D G3DSA:3.40.50.2300 1 134 7.1E-38 T 01-11-2018 MLA2C4_25050 29a743c2b6bf84c6e3f2c960d1742c90 229 SUPERFAMILY SSF52172 3 178 6.45E-41 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_26025 387f640f12b19b09158080de839926f0 240 Pfam PF00753 Metallo-beta-lactamase superfamily 18 212 1.2E-28 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_26025 387f640f12b19b09158080de839926f0 240 SUPERFAMILY SSF56281 6 227 1.27E-43 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_26025 387f640f12b19b09158080de839926f0 240 Gene3D G3DSA:3.60.15.10 5 239 9.0E-40 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_26025 387f640f12b19b09158080de839926f0 240 SMART SM00849 20 212 1.7E-34 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_28010 4d256f5aa9d2efb94d8024243f79d3b6 433 Gene3D G3DSA:3.40.640.10 7 287 1.4E-89 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_28010 4d256f5aa9d2efb94d8024243f79d3b6 433 SUPERFAMILY SSF53383 24 422 5.63E-111 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_28010 4d256f5aa9d2efb94d8024243f79d3b6 433 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 422 1.9E-126 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_28010 4d256f5aa9d2efb94d8024243f79d3b6 433 PIRSF PIRSF001434 3 424 6.4E-123 T 01-11-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MLA2C4_28010 4d256f5aa9d2efb94d8024243f79d3b6 433 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 422 6.2E-182 T 01-11-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 MLA2C4_28010 4d256f5aa9d2efb94d8024243f79d3b6 433 Gene3D G3DSA:3.90.1150.10 291 432 6.5E-51 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 SUPERFAMILY SSF109604 500 651 7.22E-13 T 01-11-2018 MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 SMART SM00471 497 653 3.8E-10 T 01-11-2018 IPR003607 HD/PDEase domain MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 Pfam PF07697 7TM-HD extracellular 51 270 3.8E-34 T 01-11-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 Pfam PF07698 7TM receptor with intracellular HD hydrolase 277 476 1.8E-43 T 01-11-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 Pfam PF01966 HD domain 501 643 5.1E-17 T 01-11-2018 IPR006674 HD domain MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 TIGRFAM TIGR00277 HDIG: HDIG domain 498 596 2.4E-26 T 01-11-2018 IPR006675 HDIG domain MLA2C4_22480 3f7f92a923c0012d2da981a4355e6a37 714 Gene3D G3DSA:1.10.3210.10 473 670 1.6E-24 T 01-11-2018 MLA2C4_04790 25ad3c6a22f8865397f5ea57e3cae1d4 367 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 2 306 1.1E-105 T 01-11-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB MLA2C4_04790 25ad3c6a22f8865397f5ea57e3cae1d4 367 SUPERFAMILY SSF53756 13 285 1.48E-8 T 01-11-2018 MLA2C4_04790 25ad3c6a22f8865397f5ea57e3cae1d4 367 Pfam PF04230 Polysaccharide pyruvyl transferase 13 288 4.3E-55 T 01-11-2018 IPR007345 Polysaccharide pyruvyl transferase MLA2C4_17350 16901aa34b41c49de00145aadf257eef 159 Gene3D G3DSA:3.50.30.40 1 159 1.2E-58 T 01-11-2018 MLA2C4_17350 16901aa34b41c49de00145aadf257eef 159 Pfam PF03737 Aldolase/RraA 4 152 2.2E-41 T 01-11-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MLA2C4_17350 16901aa34b41c49de00145aadf257eef 159 SUPERFAMILY SSF89562 3 157 1.31E-42 T 01-11-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MLA2C4_17350 16901aa34b41c49de00145aadf257eef 159 TIGRFAM TIGR01935 NOT-MenG: RraA family 4 153 3.5E-54 T 01-11-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 SMART SM00963 22 103 4.5E-26 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 SUPERFAMILY SSF47364 18 96 1.14E-22 T 01-11-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 SMART SM00962 120 321 5.3E-123 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 SUPERFAMILY SSF52540 117 319 1.81E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 Gene3D G3DSA:3.40.50.300 107 309 4.0E-117 T 01-11-2018 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 6.0E-82 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 4.3E-119 T 01-11-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 SMART SM00382 119 297 4.6E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.077 T 01-11-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 Gene3D G3DSA:1.20.120.140 20 318 4.0E-117 T 01-11-2018 MLA2C4_20105 68dfad27ad0194d51004ed2cd6237109 329 Pfam PF02881 SRP54-type protein, helical bundle domain 34 99 6.4E-15 T 01-11-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.669 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 PRINTS PR00094 Adenylate kinase signature 177 191 4.1E-33 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 PRINTS PR00094 Adenylate kinase signature 4 17 4.1E-33 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 PRINTS PR00094 Adenylate kinase signature 81 97 4.1E-33 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 PRINTS PR00094 Adenylate kinase signature 160 175 4.1E-33 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 PRINTS PR00094 Adenylate kinase signature 32 46 4.1E-33 T 01-11-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 SUPERFAMILY SSF52540 1 212 8.84E-44 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 2.9E-17 T 01-11-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 Pfam PF00406 Adenylate kinase 5 189 4.7E-60 T 01-11-2018 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 3.4E-78 T 01-11-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 Gene3D G3DSA:3.40.50.300 1 212 2.7E-80 T 01-11-2018 MLA2C4_00780 bd98344da79b50d3ed206c783afebbf4 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 01-11-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MLA2C4_09685 cebc4249dcae98566d5363686b52f45d 406 Pfam PF07690 Major Facilitator Superfamily 24 358 2.1E-33 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_09685 cebc4249dcae98566d5363686b52f45d 406 Gene3D G3DSA:1.20.1250.20 16 404 1.4E-36 T 01-11-2018 MLA2C4_09685 cebc4249dcae98566d5363686b52f45d 406 SUPERFAMILY SSF103473 18 403 1.83E-45 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_21750 5b4d10d2dafbe9967529539041a35114 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 342 366 - T 01-11-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_21750 5b4d10d2dafbe9967529539041a35114 392 Pfam PF01098 Cell cycle protein 15 383 5.5E-86 T 01-11-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 PIRSF PIRSF001357 1 223 2.0E-80 T 01-11-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 Gene3D G3DSA:3.20.20.70 1 218 1.2E-96 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 SMART SM01133 2 214 1.2E-105 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 Pfam PF01791 DeoC/LacD family aldolase 4 205 9.3E-23 T 01-11-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.457 T 01-11-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 SUPERFAMILY SSF51569 1 214 1.88E-83 T 01-11-2018 MLA2C4_09620 70d5390cf15b4fc9276c1c4cdfe294cb 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 1.9E-93 T 01-11-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MLA2C4_07265 4d0fdb155fca348888af3f62e1a658ba 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 5 77 1.4E-35 T 01-11-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 MLA2C4_07265 4d0fdb155fca348888af3f62e1a658ba 79 Hamap MF_00565 D-alanyl carrier protein [dltC]. 1 79 45.497 T 01-11-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 MLA2C4_07265 4d0fdb155fca348888af3f62e1a658ba 79 SUPERFAMILY SSF47336 2 77 2.36E-13 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_07265 4d0fdb155fca348888af3f62e1a658ba 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 9.6E-9 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_07265 4d0fdb155fca348888af3f62e1a658ba 79 Gene3D G3DSA:1.10.1200.10 2 79 1.5E-21 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_16420 b1acd76498d51715ee2859536ab0e473 397 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 11 393 1.4E-95 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_16420 b1acd76498d51715ee2859536ab0e473 397 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 224 391 7.0E-37 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_16420 b1acd76498d51715ee2859536ab0e473 397 Gene3D G3DSA:3.30.300.210 240 394 1.4E-42 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 SUPERFAMILY SSF51905 6 380 1.77E-54 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 Gene3D G3DSA:3.30.9.50 42 274 1.3E-69 T 01-11-2018 MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.5E-14 T 01-11-2018 MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.5E-14 T 01-11-2018 MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.5E-14 T 01-11-2018 MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.5E-14 T 01-11-2018 MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 Pfam PF01494 FAD binding domain 6 343 2.5E-20 T 01-11-2018 IPR002938 FAD-binding domain GO:0071949 MLA2C4_04995 2e005dc77202f81c1bfbd56d8d4fe44e 399 Gene3D G3DSA:3.50.50.60 9 345 1.3E-69 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_11655 816740daac823d1b349f25cb8ca84ebd 95 SMART SM00966 8 51 2.0E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_11655 816740daac823d1b349f25cb8ca84ebd 95 SUPERFAMILY SSF89447 1 53 8.37E-16 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily MLA2C4_11655 816740daac823d1b349f25cb8ca84ebd 95 Gene3D G3DSA:2.10.260.10 1 51 5.2E-23 T 01-11-2018 MLA2C4_11655 816740daac823d1b349f25cb8ca84ebd 95 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 47 1.1E-10 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_11655 816740daac823d1b349f25cb8ca84ebd 95 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 46 9.6E-13 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_25515 05162286233fe645959dd87915779670 396 Gene3D G3DSA:3.90.1150.10 25 379 2.1E-130 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_25515 05162286233fe645959dd87915779670 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MLA2C4_25515 05162286233fe645959dd87915779670 396 SUPERFAMILY SSF53383 8 385 1.75E-117 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_25515 05162286233fe645959dd87915779670 396 Gene3D G3DSA:3.40.640.10 61 282 2.1E-130 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_25515 05162286233fe645959dd87915779670 396 Pfam PF00155 Aminotransferase class I and II 30 378 1.9E-70 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_05025 482b61b09a104991a6bb86b1832d79dc 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 64 6.0E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05025 482b61b09a104991a6bb86b1832d79dc 191 Gene3D G3DSA:1.10.357.10 9 181 2.2E-30 T 01-11-2018 MLA2C4_05025 482b61b09a104991a6bb86b1832d79dc 191 SUPERFAMILY SSF46689 10 75 1.65E-11 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_22865 f0b87ae3731140b2e924ffb170de5187 213 SUPERFAMILY SSF53335 3 212 1.46E-45 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_22865 f0b87ae3731140b2e924ffb170de5187 213 Gene3D G3DSA:3.40.50.150 1 212 6.2E-64 T 01-11-2018 MLA2C4_22865 f0b87ae3731140b2e924ffb170de5187 213 Pfam PF01596 O-methyltransferase 41 211 4.9E-35 T 01-11-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 MLA2C4_00795 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 01-11-2018 MLA2C4_00795 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 01-11-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00795 7daf4c47f7f7eb87b15e0b26d32f1de9 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.2E-24 T 01-11-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00795 7daf4c47f7f7eb87b15e0b26d32f1de9 37 SUPERFAMILY SSF57840 1 37 6.41E-17 T 01-11-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00795 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Pfam PF00444 Ribosomal protein L36 1 37 5.7E-19 T 01-11-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00795 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.778 T 01-11-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_16125 be2052c2dd94c15ef69d4ec9537b26a0 285 PIRSF PIRSF016184 1 281 1.8E-81 T 01-11-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MLA2C4_16125 be2052c2dd94c15ef69d4ec9537b26a0 285 Pfam PF02567 Phenazine biosynthesis-like protein 9 273 2.1E-55 T 01-11-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MLA2C4_16125 be2052c2dd94c15ef69d4ec9537b26a0 285 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 281 6.1E-57 T 01-11-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MLA2C4_16125 be2052c2dd94c15ef69d4ec9537b26a0 285 Gene3D G3DSA:3.10.310.10 1 125 1.2E-32 T 01-11-2018 MLA2C4_16125 be2052c2dd94c15ef69d4ec9537b26a0 285 Gene3D G3DSA:3.10.310.10 129 270 2.0E-43 T 01-11-2018 MLA2C4_16125 be2052c2dd94c15ef69d4ec9537b26a0 285 SUPERFAMILY SSF54506 1 277 2.62E-70 T 01-11-2018 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SMART SM00248 71 99 1700.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SMART SM00248 136 165 0.2 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SMART SM00248 241 271 420.0 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SMART SM00248 169 199 0.042 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SMART SM00248 103 132 0.001 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SMART SM00248 203 237 3.1 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 SUPERFAMILY SSF48403 74 266 8.63E-49 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 Pfam PF12796 Ankyrin repeats (3 copies) 143 238 1.4E-14 T 01-11-2018 IPR020683 Ankyrin repeat-containing domain MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 Gene3D G3DSA:1.25.40.20 71 267 1.5E-52 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 Pfam PF00023 Ankyrin repeat 103 134 0.022 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 PRINTS PR01415 Ankyrin repeat signature 170 185 3.6E-7 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_03030 e0424c0fc1452c14828d817fb69685ee 278 PRINTS PR01415 Ankyrin repeat signature 224 238 3.6E-7 T 01-11-2018 IPR002110 Ankyrin repeat GO:0005515 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Gene3D G3DSA:3.40.50.300 327 746 3.0E-140 T 01-11-2018 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Gene3D G3DSA:2.30.30.940 598 677 3.0E-140 T 01-11-2018 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Pfam PF13538 UvrD-like helicase C-terminal domain 676 724 3.7E-16 T 01-11-2018 IPR027785 UvrD-like helicase C-terminal domain MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 20 750 3.0E-246 T 01-11-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 753 29.566 T 01-11-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Gene3D G3DSA:3.40.50.300 512 740 3.0E-140 T 01-11-2018 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Gene3D G3DSA:1.10.10.2220 198 307 1.2E-14 T 01-11-2018 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 SUPERFAMILY SSF52540 334 730 1.48E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Pfam PF13604 AAA domain 341 548 2.4E-49 T 01-11-2018 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Gene3D G3DSA:1.10.150.20 94 157 3.6E-5 T 01-11-2018 MLA2C4_22920 e376d9e4c418a80e3816dc675f06f661 778 Pfam PF14490 Helix-hairpin-helix containing domain 156 247 1.6E-28 T 01-11-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain MLA2C4_02045 cb949e3f879ce0afbd9bc472a8221600 213 SMART SM01007 8 184 4.7E-59 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal MLA2C4_02045 cb949e3f879ce0afbd9bc472a8221600 213 Gene3D G3DSA:3.40.225.10 1 213 3.4E-74 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MLA2C4_02045 cb949e3f879ce0afbd9bc472a8221600 213 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 184 1.4E-43 T 01-11-2018 IPR001303 Class II aldolase/adducin N-terminal MLA2C4_02045 cb949e3f879ce0afbd9bc472a8221600 213 SUPERFAMILY SSF53639 2 212 1.22E-62 T 01-11-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MLA2C4_01270 9c7a56d3fa16ee9f3f58b79e4db24f4a 310 Gene3D G3DSA:3.40.50.300 1 230 1.5E-71 T 01-11-2018 MLA2C4_01270 9c7a56d3fa16ee9f3f58b79e4db24f4a 310 SMART SM00382 26 208 1.6E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01270 9c7a56d3fa16ee9f3f58b79e4db24f4a 310 Pfam PF00005 ABC transporter 17 160 1.3E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01270 9c7a56d3fa16ee9f3f58b79e4db24f4a 310 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01270 9c7a56d3fa16ee9f3f58b79e4db24f4a 310 SUPERFAMILY SSF52540 2 225 1.7E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22490 1af136947f2ae784732882668c45e7de 399 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 387 3.2E-150 T 01-11-2018 IPR010690 Putative stage IV sporulation YqfD MLA2C4_22490 1af136947f2ae784732882668c45e7de 399 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 385 3.5E-120 T 01-11-2018 IPR010690 Putative stage IV sporulation YqfD MLA2C4_22490 1af136947f2ae784732882668c45e7de 399 PIRSF PIRSF029895 1 398 3.6E-172 T 01-11-2018 IPR010690 Putative stage IV sporulation YqfD MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 SUPERFAMILY SSF51445 7 199 5.58E-56 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 SMART SM00641 9 113 1.3E-11 T 01-11-2018 IPR018077 Glycoside hydrolase, family 25 subgroup MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 Pfam PF08239 Bacterial SH3 domain 235 270 2.2E-7 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 Gene3D G3DSA:3.20.20.80 1 211 3.0E-63 T 01-11-2018 MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 SMART SM00287 287 344 0.18 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 SMART SM00287 226 283 0.0023 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 Pfam PF01183 Glycosyl hydrolases family 25 12 190 6.2E-53 T 01-11-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 Gene3D G3DSA:2.30.30.40 281 342 1.3E-6 T 01-11-2018 MLA2C4_19135 eadfa32a7d52bf5c8443307e54534108 349 Gene3D G3DSA:2.30.30.40 218 277 1.5E-9 T 01-11-2018 MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 SMART SM00347 22 124 1.6E-23 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 Pfam PF01047 MarR family 31 89 1.3E-14 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 SUPERFAMILY SSF46785 17 136 1.62E-28 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 Gene3D G3DSA:1.10.10.10 11 157 1.8E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 9.8E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 9.8E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 9.8E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_01895 89f445781c9e13faaf497a230ec79cdb 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 9.8E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_00095 bc3eda49e8350ca3cff9b60fa523084d 130 Pfam PF04545 Sigma-70, region 4 83 115 4.7E-7 T 01-11-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MLA2C4_00095 bc3eda49e8350ca3cff9b60fa523084d 130 Pfam PF12677 Domain of unknown function (DUF3797) 1 54 2.7E-25 T 01-11-2018 IPR024256 Domain of unknown function DUF3797 MLA2C4_11285 bb21e324d4faf0c4102ddabb8bc17f72 291 SUPERFAMILY SSF56752 4 282 3.92E-80 T 01-11-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MLA2C4_11285 bb21e324d4faf0c4102ddabb8bc17f72 291 Gene3D G3DSA:3.30.470.10 1 126 3.3E-33 T 01-11-2018 MLA2C4_11285 bb21e324d4faf0c4102ddabb8bc17f72 291 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 01-11-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MLA2C4_11285 bb21e324d4faf0c4102ddabb8bc17f72 291 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 9 284 1.3E-93 T 01-11-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 MLA2C4_11285 bb21e324d4faf0c4102ddabb8bc17f72 291 Gene3D G3DSA:3.20.10.10 129 286 1.7E-56 T 01-11-2018 MLA2C4_11285 bb21e324d4faf0c4102ddabb8bc17f72 291 Pfam PF01063 Amino-transferase class IV 37 259 1.7E-52 T 01-11-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MLA2C4_01170 36953d77134b918994fa7a0904174bfe 288 SUPERFAMILY SSF53850 88 282 5.19E-33 T 01-11-2018 MLA2C4_01170 36953d77134b918994fa7a0904174bfe 288 Gene3D G3DSA:1.10.10.10 1 88 1.7E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_01170 36953d77134b918994fa7a0904174bfe 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.0E-21 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_01170 36953d77134b918994fa7a0904174bfe 288 SUPERFAMILY SSF46785 1 101 1.71E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_01170 36953d77134b918994fa7a0904174bfe 288 Pfam PF03466 LysR substrate binding domain 86 282 4.2E-39 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_01170 36953d77134b918994fa7a0904174bfe 288 Gene3D G3DSA:3.40.190.290 90 286 5.2E-35 T 01-11-2018 MLA2C4_13505 4cab01236d4fd42ce5a5333dc1161bf8 186 SUPERFAMILY SSF52540 3 162 1.43E-20 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13505 4cab01236d4fd42ce5a5333dc1161bf8 186 Gene3D G3DSA:3.40.50.300 1 180 7.7E-25 T 01-11-2018 MLA2C4_13505 4cab01236d4fd42ce5a5333dc1161bf8 186 Pfam PF13238 AAA domain 8 129 9.4E-8 T 01-11-2018 MLA2C4_10150 36b806b2c4d7c790100a62872fd6babd 386 SMART SM00460 179 235 5.3E-7 T 01-11-2018 IPR002931 Transglutaminase-like MLA2C4_10150 36b806b2c4d7c790100a62872fd6babd 386 Pfam PF01841 Transglutaminase-like superfamily 140 232 1.2E-13 T 01-11-2018 IPR002931 Transglutaminase-like MLA2C4_10150 36b806b2c4d7c790100a62872fd6babd 386 SUPERFAMILY SSF54001 132 270 2.73E-24 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_10150 36b806b2c4d7c790100a62872fd6babd 386 Gene3D G3DSA:3.10.620.30 90 250 1.9E-21 T 01-11-2018 MLA2C4_19475 07b62aa82906218df01261e0c50eb71a 159 SUPERFAMILY SSF55729 4 155 9.12E-34 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_19475 07b62aa82906218df01261e0c50eb71a 159 Gene3D G3DSA:3.40.630.30 1 157 1.5E-36 T 01-11-2018 MLA2C4_19475 07b62aa82906218df01261e0c50eb71a 159 Pfam PF13673 Acetyltransferase (GNAT) domain 31 153 1.4E-18 T 01-11-2018 IPR000182 GNAT domain MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 Gene3D G3DSA:1.10.260.50 15 278 1.0E-141 T 01-11-2018 MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 PIRSF PIRSF005572 1 381 9.0E-123 T 01-11-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 Gene3D G3DSA:3.90.1150.10 4 368 1.0E-141 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 SUPERFAMILY SSF53383 3 374 1.46E-103 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 01-11-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 Pfam PF00266 Aminotransferase class-V 4 366 4.3E-83 T 01-11-2018 IPR000192 Aminotransferase class V domain MLA2C4_22935 9f78a073917b43dc297484be47b422f2 381 Gene3D G3DSA:3.40.640.10 61 235 1.0E-141 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_15830 42ab8b612db724dbb26da0c0d0afdb3e 192 SUPERFAMILY SSF56784 3 168 6.64E-29 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_15830 42ab8b612db724dbb26da0c0d0afdb3e 192 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 3 158 4.6E-7 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_15830 42ab8b612db724dbb26da0c0d0afdb3e 192 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 163 5.7E-18 T 01-11-2018 MLA2C4_15830 42ab8b612db724dbb26da0c0d0afdb3e 192 Gene3D G3DSA:3.40.50.1000 3 159 2.5E-30 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_15830 42ab8b612db724dbb26da0c0d0afdb3e 192 Gene3D G3DSA:1.10.150.240 13 73 2.5E-30 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_14085 fcae75c3b2255558bf19d4542b003157 392 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 275 369 5.5E-14 T 01-11-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 MLA2C4_14085 fcae75c3b2255558bf19d4542b003157 392 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 391 3.6E-93 T 01-11-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 MLA2C4_14085 fcae75c3b2255558bf19d4542b003157 392 Gene3D G3DSA:3.40.50.2000 7 386 5.6E-101 T 01-11-2018 MLA2C4_14085 fcae75c3b2255558bf19d4542b003157 392 Gene3D G3DSA:3.40.50.2000 212 375 5.6E-101 T 01-11-2018 MLA2C4_14085 fcae75c3b2255558bf19d4542b003157 392 SUPERFAMILY SSF53756 3 389 1.37E-73 T 01-11-2018 MLA2C4_03465 18781eb944ed22b080f64a03498344b1 592 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 110 499 6.9E-87 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_03465 18781eb944ed22b080f64a03498344b1 592 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 110 132 - T 01-11-2018 IPR023765 Solute-binding protein family 5, conserved site MLA2C4_03465 18781eb944ed22b080f64a03498344b1 592 PIRSF PIRSF002741 4 586 2.1E-93 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_03465 18781eb944ed22b080f64a03498344b1 592 Gene3D G3DSA:3.10.105.10 318 552 6.4E-81 T 01-11-2018 MLA2C4_03465 18781eb944ed22b080f64a03498344b1 592 Gene3D G3DSA:3.40.190.10 31 317 1.1E-53 T 01-11-2018 MLA2C4_03465 18781eb944ed22b080f64a03498344b1 592 SUPERFAMILY SSF53850 57 581 6.33E-116 T 01-11-2018 MLA2C4_11870 cd911a641d441662a85a2106d55ed751 153 Pfam PF10934 Protein of unknown function (DUF2634) 32 128 2.1E-14 T 01-11-2018 IPR020288 Protein of unknown function DUF2634 MLA2C4_11870 cd911a641d441662a85a2106d55ed751 153 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 52 147 1.0E-8 T 01-11-2018 IPR020288 Protein of unknown function DUF2634 MLA2C4_01945 1a2cf7ba381240631eeafd89b8e03086 107 Pfam PF00893 Small Multidrug Resistance protein 3 93 3.4E-25 T 01-11-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MLA2C4_01945 1a2cf7ba381240631eeafd89b8e03086 107 Gene3D G3DSA:1.10.3730.20 1 107 2.5E-32 T 01-11-2018 MLA2C4_01945 1a2cf7ba381240631eeafd89b8e03086 107 SUPERFAMILY SSF103481 6 105 1.83E-17 T 01-11-2018 MLA2C4_18750 06d3ed5bfbf95046478cb07b2b462ae7 315 SUPERFAMILY SSF53098 8 173 9.42E-55 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_18750 06d3ed5bfbf95046478cb07b2b462ae7 315 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 10 196 3.3E-30 T 01-11-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_18750 06d3ed5bfbf95046478cb07b2b462ae7 315 SMART SM00479 9 174 6.3E-50 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_18750 06d3ed5bfbf95046478cb07b2b462ae7 315 Gene3D G3DSA:3.30.420.10 7 179 4.4E-53 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_18750 06d3ed5bfbf95046478cb07b2b462ae7 315 Pfam PF00929 Exonuclease 11 165 2.0E-35 T 01-11-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MLA2C4_05790 0126f2093e87cd5e090d1adf16a37846 42 Pfam PF14149 YhfH-like protein 3 38 3.6E-21 T 01-11-2018 IPR025432 YhfH-like protein MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 Gene3D G3DSA:3.40.50.300 256 481 6.4E-47 T 01-11-2018 MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 Pfam PF00005 ABC transporter 268 419 4.5E-25 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 SMART SM00382 275 468 6.2E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 SMART SM00382 31 219 1.7E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 SUPERFAMILY SSF52540 6 223 2.22E-56 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 SUPERFAMILY SSF52540 264 477 1.07E-47 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 Pfam PF00005 ABC transporter 22 165 5.9E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_15670 f9228dff672556ba8f33d7d1ada1b8e2 493 Gene3D G3DSA:3.40.50.300 2 229 1.4E-57 T 01-11-2018 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 Gene3D G3DSA:3.30.559.10 184 427 1.1E-90 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 SUPERFAMILY SSF52777 190 426 3.69E-88 T 01-11-2018 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 Gene3D G3DSA:4.10.320.10 97 164 2.7E-20 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 Gene3D G3DSA:2.40.50.100 2 81 2.1E-25 T 01-11-2018 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 SUPERFAMILY SSF51230 3 93 1.2E-25 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 01-11-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 Pfam PF00364 Biotin-requiring enzyme 4 75 1.2E-22 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 199 426 9.5E-89 T 01-11-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 SUPERFAMILY SSF47005 119 161 1.31E-12 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_20750 57c23467523e8d97d0fae7c1ebf18ea0 429 Pfam PF02817 e3 binding domain 122 156 1.1E-15 T 01-11-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_16510 c9a561f30aa82522a4fa135a43b55c76 611 Gene3D G3DSA:3.10.310.70 81 204 1.0E-81 T 01-11-2018 MLA2C4_16510 c9a561f30aa82522a4fa135a43b55c76 611 SUPERFAMILY SSF51556 61 494 9.83E-43 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_16510 c9a561f30aa82522a4fa135a43b55c76 611 Gene3D G3DSA:2.30.40.10 10 509 1.0E-81 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_16510 c9a561f30aa82522a4fa135a43b55c76 611 Pfam PF07969 Amidohydrolase family 52 534 5.9E-106 T 01-11-2018 IPR013108 Amidohydrolase 3 MLA2C4_16510 c9a561f30aa82522a4fa135a43b55c76 611 SUPERFAMILY SSF51338 3 538 3.38E-18 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_16510 c9a561f30aa82522a4fa135a43b55c76 611 Gene3D G3DSA:3.20.20.140 62 493 1.0E-81 T 01-11-2018 MLA2C4_01995 ce936b040b936f04f66ae5d77514081c 231 SUPERFAMILY SSF55729 18 166 5.41E-10 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_01995 ce936b040b936f04f66ae5d77514081c 231 Gene3D G3DSA:3.40.630.30 18 174 1.4E-5 T 01-11-2018 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 SMART SM00421 160 209 0.0091 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 Pfam PF04542 Sigma-70 region 2 36 105 5.5E-12 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 SUPERFAMILY SSF88659 123 210 1.57E-11 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 PIRSF PIRSF002939 5 216 3.4E-111 T 01-11-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 01-11-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 Pfam PF08281 Sigma-70, region 4 162 205 1.1E-9 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 2.9E-117 T 01-11-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 SUPERFAMILY SSF88946 17 105 9.03E-22 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_00585 a6727c7cfbd4d74359595b6d82480aed 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 4.3E-27 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 Pfam PF13489 Methyltransferase domain 94 236 2.0E-14 T 01-11-2018 MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 Pfam PF08421 Putative zinc binding domain 6 67 2.1E-22 T 01-11-2018 IPR013630 Methyltransferase putative zinc binding domain MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 Gene3D G3DSA:3.40.50.150 60 254 4.8E-45 T 01-11-2018 MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 Pfam PF08484 C-methyltransferase C-terminal domain 243 400 3.4E-61 T 01-11-2018 IPR013691 C-methyltransferase MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 Gene3D G3DSA:2.20.25.520 1 57 2.4E-20 T 01-11-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 Gene3D G3DSA:3.40.50.720 308 407 5.5E-41 T 01-11-2018 MLA2C4_17680 353b0dac76c048721ce06103a3baec79 407 SUPERFAMILY SSF53335 70 250 1.25E-23 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_27895 9dfcf154791da5203d483d6fd5775e9d 134 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 129 1.3E-63 T 01-11-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 MLA2C4_27895 9dfcf154791da5203d483d6fd5775e9d 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 129 7.5E-26 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_27895 9dfcf154791da5203d483d6fd5775e9d 134 Hamap MF_01624 Arsenate reductase [arsC]. 2 132 47.474 T 01-11-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 MLA2C4_27895 9dfcf154791da5203d483d6fd5775e9d 134 Gene3D G3DSA:3.40.50.2300 2 132 6.8E-53 T 01-11-2018 MLA2C4_27895 9dfcf154791da5203d483d6fd5775e9d 134 SMART SM00226 5 132 8.0E-55 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_27895 9dfcf154791da5203d483d6fd5775e9d 134 SUPERFAMILY SSF52788 4 130 3.79E-44 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MLA2C4_17345 2cbe2031b1c525c7024bda434a00ca6e 601 Gene3D G3DSA:1.50.10.20 296 506 8.2E-22 T 01-11-2018 MLA2C4_17345 2cbe2031b1c525c7024bda434a00ca6e 601 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 567 599 7.7E-5 T 01-11-2018 MLA2C4_17345 2cbe2031b1c525c7024bda434a00ca6e 601 SUPERFAMILY SSF81853 298 500 9.15E-26 T 01-11-2018 MLA2C4_17345 2cbe2031b1c525c7024bda434a00ca6e 601 Gene3D G3DSA:3.10.20.490 32 131 1.2E-14 T 01-11-2018 MLA2C4_17345 2cbe2031b1c525c7024bda434a00ca6e 601 Pfam PF14478 Domain of unknown function (DUF4430) 60 129 1.1E-16 T 01-11-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 MLA2C4_19325 170ba7a2563526105859cabbec85e7cc 369 SUPERFAMILY SSF53756 6 332 3.45E-57 T 01-11-2018 MLA2C4_19325 170ba7a2563526105859cabbec85e7cc 369 Pfam PF00534 Glycosyl transferases group 1 184 309 8.4E-25 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_19325 170ba7a2563526105859cabbec85e7cc 369 Pfam PF13439 Glycosyltransferase Family 4 17 175 1.6E-11 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MLA2C4_19325 170ba7a2563526105859cabbec85e7cc 369 Gene3D G3DSA:3.40.50.2000 171 302 2.0E-48 T 01-11-2018 MLA2C4_19325 170ba7a2563526105859cabbec85e7cc 369 Gene3D G3DSA:3.40.50.2000 17 170 2.0E-48 T 01-11-2018 MLA2C4_06000 b938fa26d542c1d2c2e311760fe73956 95 Gene3D G3DSA:1.10.150.20 39 95 1.7E-15 T 01-11-2018 MLA2C4_06000 b938fa26d542c1d2c2e311760fe73956 95 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 42 95 4.0E-5 T 01-11-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_06000 b938fa26d542c1d2c2e311760fe73956 95 SUPERFAMILY SSF47789 42 95 7.46E-14 T 01-11-2018 MLA2C4_06000 b938fa26d542c1d2c2e311760fe73956 95 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 42 89 1.2E-8 T 01-11-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MLA2C4_11370 fb382cebd106261e08c7736c3503280f 406 SUPERFAMILY SSF48452 215 340 3.6E-7 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_11370 fb382cebd106261e08c7736c3503280f 406 SUPERFAMILY SSF53448 15 114 1.69E-15 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_11370 fb382cebd106261e08c7736c3503280f 406 Gene3D G3DSA:1.25.40.10 178 341 4.7E-10 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_11370 fb382cebd106261e08c7736c3503280f 406 Gene3D G3DSA:3.90.550.10 1 114 3.0E-13 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_11370 fb382cebd106261e08c7736c3503280f 406 Pfam PF00535 Glycosyl transferase family 2 17 109 6.0E-8 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 01-11-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 Gene3D G3DSA:3.20.20.70 1 221 7.7E-84 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 6.4E-80 T 01-11-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 SUPERFAMILY SSF51569 1 219 1.05E-72 T 01-11-2018 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 Hamap MF_00494 Probable transaldolase [tal]. 1 221 45.222 T 01-11-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 216 3.5E-56 T 01-11-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MLA2C4_17720 1d9d25b2f8ef518a3c01ee96e7860b12 222 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 01-11-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MLA2C4_04295 bffb7e55065c862b733ab7cc474d7ab2 98 SUPERFAMILY SSF52821 2 94 3.27E-29 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04295 bffb7e55065c862b733ab7cc474d7ab2 98 Pfam PF00581 Rhodanese-like domain 5 94 6.2E-14 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04295 bffb7e55065c862b733ab7cc474d7ab2 98 Gene3D G3DSA:3.40.250.10 1 97 2.1E-29 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04295 bffb7e55065c862b733ab7cc474d7ab2 98 SMART SM00450 5 97 2.2E-17 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 Gene3D G3DSA:1.10.3860.10 1 419 8.5E-136 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 PRINTS PR00173 Glutamate-aspartate symporter signature 219 238 1.0E-37 T 01-11-2018 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 01-11-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 SUPERFAMILY SSF118215 6 402 1.83E-125 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_09140 a0480354e4608ff5840bcef0be37fe7a 423 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 1.1E-125 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Gene3D G3DSA:3.40.50.10490 243 439 7.8E-65 T 01-11-2018 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Gene3D G3DSA:3.60.20.10 2 239 1.4E-71 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Gene3D G3DSA:3.40.50.10490 444 600 1.5E-60 T 01-11-2018 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 1.3E-225 T 01-11-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.393 T 01-11-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Pfam PF13522 Glutamine amidotransferase domain 62 192 8.3E-19 T 01-11-2018 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 SUPERFAMILY SSF53697 244 600 1.3E-93 T 01-11-2018 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Pfam PF01380 SIS domain 457 582 6.5E-17 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 Pfam PF01380 SIS domain 287 413 2.7E-32 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_00975 90d8aab6d42f31ad4c51d2c7467805b5 600 SUPERFAMILY SSF56235 2 234 6.26E-64 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 Gene3D G3DSA:3.40.30.60 352 496 5.2E-36 T 01-11-2018 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 Gene3D G3DSA:1.10.490.80 590 687 1.7E-5 T 01-11-2018 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 161 9.4E-44 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 173 190 9.4E-44 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 224 238 9.4E-44 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 63 82 9.4E-44 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 124 140 9.4E-44 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 26 39 9.4E-44 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 PIRSF PIRSF005419 4 688 3.1E-182 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 Gene3D G3DSA:1.10.8.540 497 586 1.1E-13 T 01-11-2018 MLA2C4_08725 3476d47a605ea95488becaa9c72d541e 688 Pfam PF00771 FHIPEP family 20 679 6.7E-199 T 01-11-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MLA2C4_19370 b95179c43c82adff3913d6b8cac1f2f5 207 Pfam PF03458 UPF0126 domain 5 78 1.4E-19 T 01-11-2018 IPR005115 Uncharacterised domain UPF0126 MLA2C4_19370 b95179c43c82adff3913d6b8cac1f2f5 207 Pfam PF03458 UPF0126 domain 92 160 1.6E-17 T 01-11-2018 IPR005115 Uncharacterised domain UPF0126 MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PIRSF PIRSF000126 3 238 1.4E-63 T 01-11-2018 MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.3E-15 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.3E-15 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.3E-15 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 Gene3D G3DSA:3.40.50.720 3 236 3.5E-74 T 01-11-2018 MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 Pfam PF00106 short chain dehydrogenase 8 196 1.8E-66 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 SUPERFAMILY SSF51735 5 225 1.8E-72 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.2E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_09975 4c9f1996cbc0564ef2abb470bca32c5f 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-33 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_13870 0845f43c58f03102f4dfd92776c65e98 413 Pfam PF05057 Putative serine esterase (DUF676) 129 200 9.0E-5 T 01-11-2018 IPR007751 Domain of unknown function DUF676, lipase-like MLA2C4_13870 0845f43c58f03102f4dfd92776c65e98 413 Gene3D G3DSA:3.40.50.1820 24 413 1.0E-147 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_13870 0845f43c58f03102f4dfd92776c65e98 413 SUPERFAMILY SSF53474 31 388 4.5E-45 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 SUPERFAMILY SSF53092 1 136 9.42E-37 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 Gene3D G3DSA:3.90.230.10 137 362 6.6E-84 T 01-11-2018 MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 138 9.7E-29 T 01-11-2018 IPR000587 Creatinase, N-terminal GO:0016787 MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 4.1E-9 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 4.1E-9 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 4.1E-9 T 01-11-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 SUPERFAMILY SSF55920 137 363 1.57E-81 T 01-11-2018 IPR036005 Creatinase/aminopeptidase-like MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 01-11-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 Pfam PF00557 Metallopeptidase family M24 147 348 3.6E-65 T 01-11-2018 IPR000994 Peptidase M24 MLA2C4_23965 9ca71698c4861a726d31e331136abeb3 365 Gene3D G3DSA:3.40.350.10 2 136 5.0E-42 T 01-11-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 SMART SM00739 2 29 4.8E-4 T 01-11-2018 IPR005824 KOW MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 4.7E-33 T 01-11-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.631 T 01-11-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 Pfam PF00467 KOW motif 5 36 2.8E-6 T 01-11-2018 IPR005824 KOW MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 Gene3D G3DSA:2.30.30.30 1 100 4.8E-44 T 01-11-2018 IPR014722 Ribosomal protein L2, domain 2 MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 SUPERFAMILY SSF50104 1 99 4.51E-40 T 01-11-2018 IPR008991 Translation protein SH3-like domain superfamily MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 6.9E-42 T 01-11-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00730 3ce190eb303703cbd6d7df30c31f0e97 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 01-11-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_01400 84e39dbdc268405f36976d6641923576 190 Gene3D G3DSA:1.20.1540.10 8 180 9.5E-34 T 01-11-2018 IPR035952 Rhomboid-like superfamily MLA2C4_01400 84e39dbdc268405f36976d6641923576 190 SUPERFAMILY SSF144091 13 183 4.84E-37 T 01-11-2018 MLA2C4_01400 84e39dbdc268405f36976d6641923576 190 Pfam PF01694 Rhomboid family 43 183 3.2E-30 T 01-11-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MLA2C4_08600 8b21f3dbe033c57da24719078095fbd7 137 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 2 136 6.6E-39 T 01-11-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 MLA2C4_08600 8b21f3dbe033c57da24719078095fbd7 137 Pfam PF00460 Flagella basal body rod protein 5 32 4.9E-5 T 01-11-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MLA2C4_08600 8b21f3dbe033c57da24719078095fbd7 137 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 89 130 1.3E-10 T 01-11-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MLA2C4_08010 61a3c4ca03785def2693a12e00d6f10e 224 PIRSF PIRSF000032 2 224 9.2E-103 T 01-11-2018 MLA2C4_08010 61a3c4ca03785def2693a12e00d6f10e 224 Gene3D G3DSA:1.20.810.10 1 224 3.1E-89 T 01-11-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 MLA2C4_08010 61a3c4ca03785def2693a12e00d6f10e 224 SUPERFAMILY SSF81342 6 224 1.01E-61 T 01-11-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MLA2C4_08010 61a3c4ca03785def2693a12e00d6f10e 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 5.1E-49 T 01-11-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 Gene3D G3DSA:3.60.20.10 257 774 3.1E-170 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 Gene3D G3DSA:1.10.1400.10 551 683 3.1E-170 T 01-11-2018 MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 Gene3D G3DSA:1.10.439.10 32 193 1.1E-56 T 01-11-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 Pfam PF01804 Penicillin amidase 58 786 2.1E-227 T 01-11-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 SUPERFAMILY SSF56235 54 789 5.4E-231 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 Gene3D G3DSA:2.30.120.10 329 402 3.1E-170 T 01-11-2018 MLA2C4_17165 a6b4bcb4aa35661ddcd51bca76e1d562 796 PIRSF PIRSF001227 15 794 1.1E-210 T 01-11-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 MLA2C4_22985 e1b75ecd9ab42c3144a5510e894b6372 170 Gene3D G3DSA:3.40.50.2020 1 169 8.3E-59 T 01-11-2018 MLA2C4_22985 e1b75ecd9ab42c3144a5510e894b6372 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 167 2.0E-67 T 01-11-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MLA2C4_22985 e1b75ecd9ab42c3144a5510e894b6372 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.38 T 01-11-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MLA2C4_22985 e1b75ecd9ab42c3144a5510e894b6372 170 Pfam PF00156 Phosphoribosyl transferase domain 33 148 1.3E-14 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_22985 e1b75ecd9ab42c3144a5510e894b6372 170 SUPERFAMILY SSF53271 3 163 5.11E-48 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_26135 38a034466e6017f09996b1f38de9f59e 319 SUPERFAMILY SSF47473 190 282 3.36E-6 T 01-11-2018 IPR011992 EF-hand domain pair MLA2C4_02395 77f84d0c91b5b823600f4576c80f6568 350 PRINTS PR01228 Eggshell protein signature 94 109 2.0E-5 T 01-11-2018 MLA2C4_02395 77f84d0c91b5b823600f4576c80f6568 350 PRINTS PR01228 Eggshell protein signature 8 24 2.0E-5 T 01-11-2018 MLA2C4_02395 77f84d0c91b5b823600f4576c80f6568 350 PRINTS PR01228 Eggshell protein signature 122 132 2.0E-5 T 01-11-2018 MLA2C4_02395 77f84d0c91b5b823600f4576c80f6568 350 PRINTS PR01228 Eggshell protein signature 168 186 2.0E-5 T 01-11-2018 MLA2C4_02395 77f84d0c91b5b823600f4576c80f6568 350 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 317 348 5.7E-4 T 01-11-2018 MLA2C4_26895 f32be3d5fce60c2a00293f9b1cedc80a 371 Gene3D G3DSA:3.40.50.2000 192 352 1.0E-161 T 01-11-2018 MLA2C4_26895 f32be3d5fce60c2a00293f9b1cedc80a 371 SUPERFAMILY SSF53756 4 369 1.26E-139 T 01-11-2018 MLA2C4_26895 f32be3d5fce60c2a00293f9b1cedc80a 371 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 365 1.2E-120 T 01-11-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_26895 f32be3d5fce60c2a00293f9b1cedc80a 371 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 5.7E-167 T 01-11-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MLA2C4_26895 f32be3d5fce60c2a00293f9b1cedc80a 371 Gene3D G3DSA:3.40.50.2000 7 363 1.0E-161 T 01-11-2018 MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 236 7.9E-30 T 01-11-2018 MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 SUPERFAMILY SSF51735 7 237 2.5E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 Gene3D G3DSA:3.40.50.720 4 237 1.9E-41 T 01-11-2018 MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 2.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_13680 862ebb42eff2dbb83ea299a741bbc68b 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19105 b96f43b612cf15b0a3a06303d5111b4f 137 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_19105 b96f43b612cf15b0a3a06303d5111b4f 137 Gene3D G3DSA:3.90.79.10 5 137 2.8E-27 T 01-11-2018 MLA2C4_19105 b96f43b612cf15b0a3a06303d5111b4f 137 Pfam PF00293 NUDIX domain 6 120 6.8E-18 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_19105 b96f43b612cf15b0a3a06303d5111b4f 137 SUPERFAMILY SSF55811 5 132 3.38E-29 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_19105 b96f43b612cf15b0a3a06303d5111b4f 137 PRINTS PR00502 NUDIX hydrolase family signature 46 61 1.2E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_19105 b96f43b612cf15b0a3a06303d5111b4f 137 PRINTS PR00502 NUDIX hydrolase family signature 32 46 1.2E-7 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_12625 a36463c8880dd3c6ac7007aea4405685 194 Pfam PF04471 Restriction endonuclease 69 174 2.5E-15 T 01-11-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 MLA2C4_12625 a36463c8880dd3c6ac7007aea4405685 194 SUPERFAMILY SSF52980 70 177 8.04E-15 T 01-11-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MLA2C4_09740 16486c9133ead4fa5632e776e93d2e3a 143 Pfam PF02082 Transcriptional regulator 1 81 1.6E-23 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_09740 16486c9133ead4fa5632e776e93d2e3a 143 Gene3D G3DSA:1.10.10.10 1 143 2.0E-60 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09740 16486c9133ead4fa5632e776e93d2e3a 143 SUPERFAMILY SSF46785 2 137 1.09E-33 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21425 8335a2f3b3b8eb812a21cdc251974f7f 179 PRINTS PR00502 NUDIX hydrolase family signature 72 86 3.5E-5 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_21425 8335a2f3b3b8eb812a21cdc251974f7f 179 PRINTS PR00502 NUDIX hydrolase family signature 86 101 3.5E-5 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_21425 8335a2f3b3b8eb812a21cdc251974f7f 179 Pfam PF00293 NUDIX domain 43 166 1.4E-22 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_21425 8335a2f3b3b8eb812a21cdc251974f7f 179 Gene3D G3DSA:3.90.79.10 4 179 1.2E-54 T 01-11-2018 MLA2C4_21425 8335a2f3b3b8eb812a21cdc251974f7f 179 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_21425 8335a2f3b3b8eb812a21cdc251974f7f 179 SUPERFAMILY SSF55811 8 178 6.5E-51 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 226 7.1E-58 T 01-11-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 243 460 1.4E-44 T 01-11-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 SUPERFAMILY SSF103473 10 458 4.19E-46 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 Gene3D G3DSA:1.20.1250.20 2 237 2.4E-78 T 01-11-2018 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 Gene3D G3DSA:1.20.1250.20 238 461 3.4E-59 T 01-11-2018 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 154 166 - T 01-11-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 Pfam PF00854 POT family 245 428 8.9E-37 T 01-11-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MLA2C4_03630 0841df44d43ea7fabdb802e95485c2a6 461 Pfam PF00854 POT family 92 212 2.7E-29 T 01-11-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MLA2C4_15170 13fe6f3e3feddce3def3ff5ccc9ad9f4 529 SUPERFAMILY SSF55486 60 528 1.02E-71 T 01-11-2018 MLA2C4_15170 13fe6f3e3feddce3def3ff5ccc9ad9f4 529 Pfam PF01432 Peptidase family M3 262 515 1.7E-10 T 01-11-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MLA2C4_15170 13fe6f3e3feddce3def3ff5ccc9ad9f4 529 Gene3D G3DSA:1.10.1370.20 159 529 8.4E-93 T 01-11-2018 MLA2C4_20785 0acdb1ae92ddac97831c545406a80f6a 70 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 6.8E-28 T 01-11-2018 IPR009907 Protein of unknown function DUF1447 MLA2C4_20785 0acdb1ae92ddac97831c545406a80f6a 70 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 1.0E-31 T 01-11-2018 IPR009907 Protein of unknown function DUF1447 MLA2C4_20785 0acdb1ae92ddac97831c545406a80f6a 70 Gene3D G3DSA:3.10.20.730 1 58 1.4E-26 T 01-11-2018 MLA2C4_20785 0acdb1ae92ddac97831c545406a80f6a 70 Hamap MF_01553 UPF0356 protein . 1 69 22.792 T 01-11-2018 IPR009907 Protein of unknown function DUF1447 MLA2C4_13365 c8253cf53bef254c0ffe76530380a9ab 441 PIRSF PIRSF000390 47 441 8.5E-109 T 01-11-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MLA2C4_13365 c8253cf53bef254c0ffe76530380a9ab 441 Gene3D G3DSA:3.90.1150.10 316 441 3.5E-27 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_13365 c8253cf53bef254c0ffe76530380a9ab 441 SUPERFAMILY SSF53383 86 439 6.61E-89 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_13365 c8253cf53bef254c0ffe76530380a9ab 441 Gene3D G3DSA:3.40.640.10 1 314 1.7E-101 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_13365 c8253cf53bef254c0ffe76530380a9ab 441 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 87 435 4.6E-105 T 01-11-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 Pfam PF00270 DEAD/DEAH box helicase 22 186 1.0E-42 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 Gene3D G3DSA:3.40.50.300 204 386 1.4E-42 T 01-11-2018 MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 SMART SM00490 248 329 3.7E-31 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 SMART SM00487 17 213 7.1E-51 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 Pfam PF00271 Helicase conserved C-terminal domain 232 329 2.3E-26 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 SUPERFAMILY SSF52540 66 347 1.05E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10730 ecccc1d1d458e6b8912308b17d3091c7 389 Gene3D G3DSA:3.40.50.300 3 202 5.3E-62 T 01-11-2018 MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 78 617 1.0E-183 T 01-11-2018 MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 Gene3D G3DSA:1.10.3810.10 59 256 1.5E-74 T 01-11-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 Pfam PF00905 Penicillin binding protein transpeptidase domain 336 613 3.4E-39 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 SUPERFAMILY SSF56601 222 627 4.08E-112 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 Pfam PF00912 Transglycosylase 69 240 2.0E-61 T 01-11-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 SUPERFAMILY SSF53955 55 262 4.78E-73 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_07675 7004e68298e4fe14b1cb85ff7b040d01 680 Gene3D G3DSA:3.40.710.10 268 618 2.2E-124 T 01-11-2018 MLA2C4_15675 f575fb3af745cfd28e7747aa3ae24e07 310 Gene3D G3DSA:3.40.50.1360 58 310 5.6E-68 T 01-11-2018 MLA2C4_15675 f575fb3af745cfd28e7747aa3ae24e07 310 Pfam PF04198 Putative sugar-binding domain 62 304 5.1E-63 T 01-11-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MLA2C4_15675 f575fb3af745cfd28e7747aa3ae24e07 310 Gene3D G3DSA:1.10.10.10 1 54 2.1E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15675 f575fb3af745cfd28e7747aa3ae24e07 310 SUPERFAMILY SSF100950 62 306 9.77E-61 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_25225 938d978e1d9e305735d4c58d76d2c100 366 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 4 364 4.0E-174 T 01-11-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 MLA2C4_25225 938d978e1d9e305735d4c58d76d2c100 366 Gene3D G3DSA:2.30.40.10 7 361 8.7E-115 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_25225 938d978e1d9e305735d4c58d76d2c100 366 Gene3D G3DSA:3.20.20.140 52 316 8.7E-115 T 01-11-2018 MLA2C4_25225 938d978e1d9e305735d4c58d76d2c100 366 SUPERFAMILY SSF51556 52 316 3.96E-66 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_25225 938d978e1d9e305735d4c58d76d2c100 366 PIRSF PIRSF039004 1 366 3.1E-137 T 01-11-2018 IPR020043 Deacetylase Atu3266-like GO:0019213 MLA2C4_25225 938d978e1d9e305735d4c58d76d2c100 366 SUPERFAMILY SSF51338 5 363 3.93E-13 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_26730 b3fac9f0cc4bf355186debf85fca5d2e 143 Pfam PF14275 Domain of unknown function (DUF4362) 30 122 4.2E-34 T 01-11-2018 IPR025372 Protein of unknown function DUF4362 MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 SMART SM00382 358 544 6.1E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 SUPERFAMILY SSF52540 322 569 1.55E-92 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 Gene3D G3DSA:1.20.1560.10 1 315 5.5E-84 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 Pfam PF00005 ABC transporter 349 498 2.6E-37 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 Gene3D G3DSA:3.40.50.300 318 570 2.3E-92 T 01-11-2018 MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 Pfam PF00664 ABC transporter transmembrane region 17 286 1.5E-56 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 SUPERFAMILY SSF90123 3 316 3.01E-80 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_26800 ffc3ab61780b3ec0c8adfe6e6d61ab21 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_28450 abf10f51a400df5d7bef82582a410b4e 239 Pfam PF02527 rRNA small subunit methyltransferase G 21 203 2.7E-57 T 01-11-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MLA2C4_28450 abf10f51a400df5d7bef82582a410b4e 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.401 T 01-11-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MLA2C4_28450 abf10f51a400df5d7bef82582a410b4e 239 Gene3D G3DSA:3.40.50.150 1 239 7.4E-88 T 01-11-2018 MLA2C4_28450 abf10f51a400df5d7bef82582a410b4e 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 216 1.1E-51 T 01-11-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MLA2C4_28450 abf10f51a400df5d7bef82582a410b4e 239 SUPERFAMILY SSF53335 1 237 1.95E-49 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_28450 abf10f51a400df5d7bef82582a410b4e 239 PIRSF PIRSF003078 1 220 1.1E-59 T 01-11-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MLA2C4_05825 026add882011c82a6b3b63b5de436d91 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 59 1.4E-5 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05825 026add882011c82a6b3b63b5de436d91 181 SUPERFAMILY SSF46689 5 72 2.26E-14 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05825 026add882011c82a6b3b63b5de436d91 181 Gene3D G3DSA:1.10.357.10 5 174 6.4E-39 T 01-11-2018 MLA2C4_05825 026add882011c82a6b3b63b5de436d91 181 Pfam PF14278 Transcriptional regulator C-terminal region 88 157 1.8E-12 T 01-11-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type MLA2C4_06275 87d73beb411020a5ee1cfacea3d58095 414 Pfam PF06054 Competence protein CoiA-like family 4 251 1.5E-62 T 01-11-2018 IPR010330 Competence-induced protein CoiA-like MLA2C4_06275 87d73beb411020a5ee1cfacea3d58095 414 PIRSF PIRSF007487 4 387 1.1E-103 T 01-11-2018 IPR021176 Competence-induced protein CoiA MLA2C4_17505 b1623a529328c4ca32af513c21363ef9 340 Gene3D G3DSA:3.90.190.10 89 337 1.1E-60 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like MLA2C4_17505 b1623a529328c4ca32af513c21363ef9 340 Pfam PF13350 Tyrosine phosphatase family 88 338 4.0E-66 T 01-11-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type MLA2C4_17505 b1623a529328c4ca32af513c21363ef9 340 SUPERFAMILY SSF52799 88 337 1.02E-54 T 01-11-2018 IPR029021 Protein-tyrosine phosphatase-like MLA2C4_11950 31f5253c7aa19a173e61571cd8e9b382 396 Pfam PF01580 FtsK/SpoIIIE family 132 244 7.4E-16 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_11950 31f5253c7aa19a173e61571cd8e9b382 396 SUPERFAMILY SSF52540 128 371 2.83E-13 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11950 31f5253c7aa19a173e61571cd8e9b382 396 Gene3D G3DSA:3.40.50.300 112 382 1.1E-45 T 01-11-2018 MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 Pfam PF00005 ABC transporter 338 464 4.6E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 SUPERFAMILY SSF52540 3 259 6.53E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 SMART SM00382 28 233 2.1E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 SMART SM00382 345 510 2.0E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 Pfam PF12848 ABC transporter 228 303 2.6E-20 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 Pfam PF00005 ABC transporter 21 189 7.0E-23 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 SUPERFAMILY SSF52540 310 506 3.23E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 Gene3D G3DSA:3.40.50.300 2 285 1.9E-61 T 01-11-2018 MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 Gene3D G3DSA:3.40.50.300 286 514 3.3E-49 T 01-11-2018 MLA2C4_02325 938a3a5e633e88c1f03c6bd05af74730 514 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_20440 ad0984b197a72f8e102e291a16a10311 363 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 6 359 7.6E-174 T 01-11-2018 IPR013438 Sporulation stage V, protein E MLA2C4_20440 ad0984b197a72f8e102e291a16a10311 363 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 319 343 - T 01-11-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20440 ad0984b197a72f8e102e291a16a10311 363 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 6 360 2.4E-131 T 01-11-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_20440 ad0984b197a72f8e102e291a16a10311 363 Pfam PF01098 Cell cycle protein 9 362 6.9E-126 T 01-11-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_06060 be6761067db2a1abd7f37a54a6031e0f 184 Pfam PF10949 Protein of unknown function (DUF2777) 3 182 6.6E-71 T 01-11-2018 IPR024488 Protein of unknown function DUF2777 MLA2C4_06060 be6761067db2a1abd7f37a54a6031e0f 184 ProDom PD106196 YISN IG BH1722 3 177 4.0E-98 T 01-11-2018 IPR024488 Protein of unknown function DUF2777 MLA2C4_11345 6963416eaad758f6b5bb77a509d20d8d 193 Pfam PF01965 DJ-1/PfpI family 2 176 3.6E-30 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_11345 6963416eaad758f6b5bb77a509d20d8d 193 Gene3D G3DSA:3.40.50.880 1 191 3.4E-43 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_11345 6963416eaad758f6b5bb77a509d20d8d 193 SUPERFAMILY SSF52317 1 191 1.31E-40 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_24050 ed0e4a7226727d21ba3cd41118cd68bf 176 SUPERFAMILY SSF109854 10 175 2.9E-11 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_24050 ed0e4a7226727d21ba3cd41118cd68bf 176 Gene3D G3DSA:1.20.120.450 2 176 2.3E-14 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_24050 ed0e4a7226727d21ba3cd41118cd68bf 176 Pfam PF12867 DinB superfamily 13 172 7.1E-11 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_03985 dde25b5494d890b8f106b8beabb79350 26 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 26 6.0E-8 T 01-11-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 MLA2C4_03985 dde25b5494d890b8f106b8beabb79350 26 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 3 26 1.7E-8 T 01-11-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 MLA2C4_04670 2e064e7eb1ffd31a5af2835f05099060 244 Gene3D G3DSA:3.40.50.300 1 243 3.2E-80 T 01-11-2018 MLA2C4_04670 2e064e7eb1ffd31a5af2835f05099060 244 Pfam PF00005 ABC transporter 17 169 1.5E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_04670 2e064e7eb1ffd31a5af2835f05099060 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_04670 2e064e7eb1ffd31a5af2835f05099060 244 PIRSF PIRSF039085 1 244 6.7E-117 T 01-11-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MLA2C4_04670 2e064e7eb1ffd31a5af2835f05099060 244 SMART SM00382 26 217 2.0E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_04670 2e064e7eb1ffd31a5af2835f05099060 244 SUPERFAMILY SSF52540 1 239 5.45E-82 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05455 14a8b5ee17a118802cb76d5edef4c020 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 124 2.0E-11 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_05455 14a8b5ee17a118802cb76d5edef4c020 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 172 264 5.1E-6 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_05455 14a8b5ee17a118802cb76d5edef4c020 325 SUPERFAMILY SSF54593 3 303 1.81E-45 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_05455 14a8b5ee17a118802cb76d5edef4c020 325 Gene3D G3DSA:3.10.180.10 66 217 5.1E-109 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_05455 14a8b5ee17a118802cb76d5edef4c020 325 Gene3D G3DSA:3.10.180.10 5 309 5.1E-109 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 Gene3D G3DSA:3.50.50.60 7 298 5.3E-52 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 SUPERFAMILY SSF51905 6 323 1.34E-39 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 294 5.3E-101 T 01-11-2018 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 Gene3D G3DSA:3.50.50.60 136 253 5.3E-52 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 323 1.4E-139 T 01-11-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 4.8E-12 T 01-11-2018 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 4.8E-12 T 01-11-2018 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.8E-12 T 01-11-2018 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 4.8E-12 T 01-11-2018 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 290 308 9.7E-15 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 9.7E-15 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 9.7E-15 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_07870 1f5b22a589d7d7c78f4169cb9487eb87 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 9.7E-15 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 2.7E-32 T 01-11-2018 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 449 464 2.7E-32 T 01-11-2018 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 2.7E-32 T 01-11-2018 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 2.7E-32 T 01-11-2018 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:3.50.30.10 7 234 4.9E-82 T 01-11-2018 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF47831 25 144 1.12E-37 T 01-11-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 PIRSF PIRSF000732 1 570 1.8E-226 T 01-11-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 568 1.7E-255 T 01-11-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF52009 126 247 3.66E-38 T 01-11-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 9.6E-24 T 01-11-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 8.5E-34 T 01-11-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF51621 251 551 1.73E-111 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:3.20.20.60 235 570 2.7E-126 T 01-11-2018 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 542 4.1E-126 T 01-11-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 449 467 - T 01-11-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 01-11-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MLA2C4_21170 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:1.10.274.10 24 147 4.9E-82 T 01-11-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MLA2C4_09215 3b80c8ed0bf4919a27e2b04098f471d9 203 Pfam PF13761 Domain of unknown function (DUF4166) 16 199 1.3E-59 T 01-11-2018 IPR025311 Domain of unknown function DUF4166 MLA2C4_14305 c07b658618ff97d41a25fb9811247eab 127 Gene3D G3DSA:3.10.28.10 1 107 1.3E-12 T 01-11-2018 IPR027434 Homing endonuclease MLA2C4_14305 c07b658618ff97d41a25fb9811247eab 127 Pfam PF14528 LAGLIDADG-like domain 40 108 1.3E-7 T 01-11-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 MLA2C4_14305 c07b658618ff97d41a25fb9811247eab 127 SUPERFAMILY SSF55608 32 123 4.16E-15 T 01-11-2018 IPR027434 Homing endonuclease MLA2C4_03960 8b89529a154e720e231423d8b2cc375d 339 Gene3D G3DSA:3.40.50.720 2 250 1.2E-73 T 01-11-2018 MLA2C4_03960 8b89529a154e720e231423d8b2cc375d 339 Pfam PF00899 ThiF family 5 241 2.6E-58 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MLA2C4_03960 8b89529a154e720e231423d8b2cc375d 339 SUPERFAMILY SSF69572 2 330 3.14E-86 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_06285 f88a4c3d1b058f02553fac5491d5ec1d 297 Pfam PF13743 Thioredoxin 25 219 2.7E-73 T 01-11-2018 MLA2C4_06285 f88a4c3d1b058f02553fac5491d5ec1d 297 Gene3D G3DSA:3.40.30.10 27 215 1.1E-23 T 01-11-2018 MLA2C4_06285 f88a4c3d1b058f02553fac5491d5ec1d 297 SUPERFAMILY SSF52833 22 227 1.17E-23 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_06285 f88a4c3d1b058f02553fac5491d5ec1d 297 Gene3D G3DSA:1.10.472.60 62 188 1.1E-23 T 01-11-2018 MLA2C4_21570 bf92920ff83ea3c62f86616a7191140d 457 Pfam PF03553 Na+/H+ antiporter family 154 444 2.9E-57 T 01-11-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MLA2C4_21570 bf92920ff83ea3c62f86616a7191140d 457 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 448 9.5E-132 T 01-11-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 MLA2C4_14295 9aaf2f60ec3e6cf24f180c6eee2c81fa 320 Gene3D G3DSA:3.60.15.10 42 315 1.0E-77 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_14295 9aaf2f60ec3e6cf24f180c6eee2c81fa 320 Pfam PF12706 Beta-lactamase superfamily domain 72 267 3.3E-39 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_14295 9aaf2f60ec3e6cf24f180c6eee2c81fa 320 SUPERFAMILY SSF56281 55 304 1.35E-36 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_14295 9aaf2f60ec3e6cf24f180c6eee2c81fa 320 PIRSF PIRSF038896 7 310 2.9E-90 T 01-11-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 MLA2C4_16215 9ac4efbf9ea5f7454b84b6bdc42f1708 156 Gene3D G3DSA:1.20.120.450 4 147 1.1E-22 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_16215 9ac4efbf9ea5f7454b84b6bdc42f1708 156 Pfam PF12867 DinB superfamily 11 139 3.9E-10 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_16215 9ac4efbf9ea5f7454b84b6bdc42f1708 156 SUPERFAMILY SSF109854 9 156 2.01E-30 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 280 9.8E-78 T 01-11-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 282 43.713 T 01-11-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 SUPERFAMILY SSF53335 3 280 3.96E-55 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 Pfam PF13847 Methyltransferase domain 113 239 1.0E-15 T 01-11-2018 IPR025714 Methyltransferase domain MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 Gene3D G3DSA:3.40.50.150 84 283 1.2E-66 T 01-11-2018 MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 Gene3D G3DSA:1.10.8.10 1 83 1.7E-16 T 01-11-2018 MLA2C4_27580 05f63c186f2922a45da4e5da4979505f 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 278 2.5E-87 T 01-11-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MLA2C4_16245 924be9094557fcfc00cd2175c4a75171 141 ProDom PD082409 MEMBRANE YVAD TRANSMEMBRANE 1 120 5.0E-44 T 01-11-2018 IPR020348 Uncharacterised protein family YvaD MLA2C4_16245 924be9094557fcfc00cd2175c4a75171 141 Pfam PF17314 Family of unknown function (DUF5360) 5 128 1.8E-59 T 01-11-2018 IPR020348 Uncharacterised protein family YvaD MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 Pfam PF00128 Alpha amylase, catalytic domain 28 376 1.3E-135 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 Gene3D G3DSA:3.20.20.80 4 472 5.2E-221 T 01-11-2018 MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 Gene3D G3DSA:3.90.400.10 105 174 5.2E-221 T 01-11-2018 MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 SMART SM00642 13 419 7.0E-172 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 553 7.1E-11 T 01-11-2018 IPR032091 Maltogenic Amylase, C-terminal MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 SUPERFAMILY SSF51011 480 557 6.72E-23 T 01-11-2018 MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 SUPERFAMILY SSF51445 3 476 6.61E-164 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_20990 44d995e219ac7204fdc2482e667aec87 558 Gene3D G3DSA:2.60.40.1180 481 558 2.9E-26 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_15885 e8207970ed94fc99222d8122bf35acb4 404 Pfam PF00202 Aminotransferase class-III 19 394 8.4E-99 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_15885 e8207970ed94fc99222d8122bf35acb4 404 Gene3D G3DSA:3.40.640.10 55 303 1.2E-124 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_15885 e8207970ed94fc99222d8122bf35acb4 404 PIRSF PIRSF000521 6 399 4.3E-43 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_15885 e8207970ed94fc99222d8122bf35acb4 404 SUPERFAMILY SSF53383 11 396 1.77E-110 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_15885 e8207970ed94fc99222d8122bf35acb4 404 Gene3D G3DSA:3.90.1150.10 8 386 1.2E-124 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_15885 e8207970ed94fc99222d8122bf35acb4 404 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_01220 859cfe8d93bc8adbc527729ee14c3a97 118 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 3 114 9.5E-14 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_01220 859cfe8d93bc8adbc527729ee14c3a97 118 SUPERFAMILY SSF159121 31 114 9.42E-18 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_01220 859cfe8d93bc8adbc527729ee14c3a97 118 Pfam PF06486 Protein of unknown function (DUF1093) 33 102 2.1E-11 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_01220 859cfe8d93bc8adbc527729ee14c3a97 118 Gene3D G3DSA:2.40.50.480 29 115 2.0E-18 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_13500 1cafb9a543db87c9c9497ddccdada35c 180 Gene3D G3DSA:3.40.630.30 9 179 6.3E-40 T 01-11-2018 MLA2C4_13500 1cafb9a543db87c9c9497ddccdada35c 180 Pfam PF13420 Acetyltransferase (GNAT) domain 13 163 1.3E-13 T 01-11-2018 MLA2C4_13500 1cafb9a543db87c9c9497ddccdada35c 180 SUPERFAMILY SSF55729 10 171 9.94E-32 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 1.3E-158 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 Pfam PF01235 Sodium:alanine symporter family 55 448 9.3E-149 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 PRINTS PR00175 Sodium/alanine symporter signature 92 114 4.0E-54 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 PRINTS PR00175 Sodium/alanine symporter signature 183 201 4.0E-54 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 PRINTS PR00175 Sodium/alanine symporter signature 306 324 4.0E-54 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 PRINTS PR00175 Sodium/alanine symporter signature 211 230 4.0E-54 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 PRINTS PR00175 Sodium/alanine symporter signature 409 429 4.0E-54 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_12250 0d8701cb9805918889f2b4e06a20b065 455 PRINTS PR00175 Sodium/alanine symporter signature 350 372 4.0E-54 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_05020 cde47977a5e7d6783d48a8def302efbf 295 SUPERFAMILY SSF103481 40 139 3.66E-10 T 01-11-2018 MLA2C4_05020 cde47977a5e7d6783d48a8def302efbf 295 Pfam PF00892 EamA-like transporter family 6 136 5.6E-16 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_05020 cde47977a5e7d6783d48a8def302efbf 295 Pfam PF00892 EamA-like transporter family 146 277 2.2E-22 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_05020 cde47977a5e7d6783d48a8def302efbf 295 SUPERFAMILY SSF103481 186 278 1.05E-14 T 01-11-2018 MLA2C4_23040 84d8c9ec575495fca6dba01de9cdce61 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 3.3E-23 T 01-11-2018 IPR021320 Protein of unknown function DUF2905 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 SMART SM00387 243 355 2.4E-39 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 Pfam PF00512 His Kinase A (phospho-acceptor) domain 133 198 3.1E-15 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 244 353 2.2E-28 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 298 308 6.9E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 333 6.9E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 352 6.9E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 280 294 6.9E-20 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 SUPERFAMILY SSF158472 85 130 1.27E-5 T 01-11-2018 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 SUPERFAMILY SSF55874 189 352 2.1E-44 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 Gene3D G3DSA:3.30.565.10 201 356 3.3E-48 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 SMART SM00388 133 199 6.2E-17 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 SUPERFAMILY SSF47384 116 199 2.16E-18 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_09940 b6d8b00551b27e554ba643670ffb6bb9 356 Gene3D G3DSA:1.10.287.130 82 194 8.4E-25 T 01-11-2018 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 Pfam PF00119 ATP synthase A chain 19 231 2.4E-57 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 Gene3D G3DSA:1.20.120.220 70 239 4.6E-41 T 01-11-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 Hamap MF_01393 ATP synthase subunit a [atpB]. 7 238 13.732 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 SUPERFAMILY SSF81336 69 231 3.92E-41 T 01-11-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 14 234 9.3E-48 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 PRINTS PR00123 ATP synthase A subunit signature 149 164 4.4E-18 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 PRINTS PR00123 ATP synthase A subunit signature 165 187 4.4E-18 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 PRINTS PR00123 ATP synthase A subunit signature 218 233 4.4E-18 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 PRINTS PR00123 ATP synthase A subunit signature 77 93 4.4E-18 T 01-11-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27490 6072efa8e6bf8a8cb089dc4926421ce4 239 ProSitePatterns PS00449 ATP synthase a subunit signature. 168 177 - T 01-11-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_01540 ef1dd031e8832239ef16714a34813475 147 SUPERFAMILY SSF55729 1 145 2.62E-37 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_01540 ef1dd031e8832239ef16714a34813475 147 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 13 143 8.6E-46 T 01-11-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MLA2C4_01540 ef1dd031e8832239ef16714a34813475 147 Gene3D G3DSA:3.40.630.30 4 147 2.3E-45 T 01-11-2018 MLA2C4_01540 ef1dd031e8832239ef16714a34813475 147 Pfam PF00583 Acetyltransferase (GNAT) family 15 123 1.4E-20 T 01-11-2018 IPR000182 GNAT domain MLA2C4_19005 117d1cf621c75fa4c98d55d8337a3561 146 ProDom PD086666 YNEK BH2332 11 146 3.0E-65 T 01-11-2018 IPR020203 Uncharacterised protein family, YneK MLA2C4_19005 117d1cf621c75fa4c98d55d8337a3561 146 Pfam PF11084 Protein of unknown function (DUF2621) 3 141 7.1E-76 T 01-11-2018 IPR020203 Uncharacterised protein family, YneK MLA2C4_12710 62c00c0a9d26c290754577ebbeb78adc 510 SUPERFAMILY SSF52058 224 474 3.74E-29 T 01-11-2018 MLA2C4_12710 62c00c0a9d26c290754577ebbeb78adc 510 Gene3D G3DSA:3.40.1580.10 4 166 2.0E-13 T 01-11-2018 IPR037883 Knr4/Smi1-like domain superfamily MLA2C4_12710 62c00c0a9d26c290754577ebbeb78adc 510 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 24 160 1.2E-26 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_12710 62c00c0a9d26c290754577ebbeb78adc 510 Gene3D G3DSA:3.80.10.10 179 492 4.4E-35 T 01-11-2018 IPR032675 Leucine-rich repeat domain superfamily MLA2C4_12710 62c00c0a9d26c290754577ebbeb78adc 510 SMART SM00860 24 164 1.1E-10 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_12710 62c00c0a9d26c290754577ebbeb78adc 510 SUPERFAMILY SSF160631 7 163 3.66E-16 T 01-11-2018 MLA2C4_23615 1e39b9b7cdc8f8a461c1292beaa27b05 256 SMART SM00382 26 215 1.8E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23615 1e39b9b7cdc8f8a461c1292beaa27b05 256 Pfam PF00005 ABC transporter 17 165 4.7E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_23615 1e39b9b7cdc8f8a461c1292beaa27b05 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_23615 1e39b9b7cdc8f8a461c1292beaa27b05 256 Gene3D G3DSA:3.40.50.300 1 253 1.5E-65 T 01-11-2018 MLA2C4_23615 1e39b9b7cdc8f8a461c1292beaa27b05 256 SUPERFAMILY SSF52540 1 224 8.54E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 15 617 1.7E-260 T 01-11-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 520 618 2.3E-22 T 01-11-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 1 619 40.869 T 01-11-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Gene3D G3DSA:2.60.40.1180 515 619 1.5E-35 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 SUPERFAMILY SSF51011 515 619 3.7E-32 T 01-11-2018 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Gene3D G3DSA:3.20.20.80 125 514 4.0E-148 T 01-11-2018 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Pfam PF00128 Alpha amylase, catalytic domain 279 472 6.6E-5 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Pfam PF00128 Alpha amylase, catalytic domain 177 249 6.9E-8 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Gene3D G3DSA:2.60.40.10 4 122 6.6E-43 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 PIRSF PIRSF000463 3 629 2.7E-261 T 01-11-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 26 108 1.8E-21 T 01-11-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 SUPERFAMILY SSF51445 81 508 8.16E-108 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_25325 b0ab54eba1eb39d23ec83016880646ac 645 SMART SM00642 152 504 2.4E-7 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 Gene3D G3DSA:1.10.10.10 5 146 3.6E-43 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 Pfam PF01047 MarR family 35 93 4.8E-19 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 SUPERFAMILY SSF46785 3 143 9.93E-33 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 SMART SM00347 28 128 3.0E-28 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 8.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 8.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 8.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_03495 482059c6a490ff02dc641facaf505ce6 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 8.7E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_27525 54cec19e9b634e670f8b8f288d000505 147 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 2.2E-48 T 01-11-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 MLA2C4_27525 54cec19e9b634e670f8b8f288d000505 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 3.2E-59 T 01-11-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MLA2C4_27525 54cec19e9b634e670f8b8f288d000505 147 Gene3D G3DSA:3.40.1400.10 1 147 2.2E-57 T 01-11-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MLA2C4_27525 54cec19e9b634e670f8b8f288d000505 147 PIRSF PIRSF005384 1 147 4.4E-57 T 01-11-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MLA2C4_27525 54cec19e9b634e670f8b8f288d000505 147 Pfam PF02502 Ribose/Galactose Isomerase 3 141 1.5E-53 T 01-11-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MLA2C4_27525 54cec19e9b634e670f8b8f288d000505 147 SUPERFAMILY SSF89623 1 145 1.05E-56 T 01-11-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 SUPERFAMILY SSF51717 15 214 2.43E-15 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 4.4E-132 T 01-11-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 35.062 T 01-11-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 Gene3D G3DSA:3.20.20.20 1 259 2.2E-110 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 Gene3D G3DSA:3.30.413.10 261 360 1.1E-34 T 01-11-2018 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 PIRSF PIRSF004640 1 365 6.0E-154 T 01-11-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 Pfam PF04551 GcpE protein 10 351 2.6E-140 T 01-11-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MLA2C4_22365 95c0c27dff3383304075eb5c1e8bc1fc 372 SUPERFAMILY SSF56014 263 352 1.8E-13 T 01-11-2018 MLA2C4_25780 71019f6bff9310cfc7a6b95fd97bb584 159 Pfam PF00583 Acetyltransferase (GNAT) family 27 136 5.9E-7 T 01-11-2018 IPR000182 GNAT domain MLA2C4_25780 71019f6bff9310cfc7a6b95fd97bb584 159 SUPERFAMILY SSF55729 1 139 6.2E-17 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_25780 71019f6bff9310cfc7a6b95fd97bb584 159 Gene3D G3DSA:3.40.630.30 1 153 3.1E-16 T 01-11-2018 MLA2C4_23330 d2f3d947dd0198012e4e30e58045a78f 204 SUPERFAMILY SSF50729 14 203 1.11E-67 T 01-11-2018 MLA2C4_23330 d2f3d947dd0198012e4e30e58045a78f 204 Pfam PF11724 YvbH-like oligomerisation region 144 204 1.1E-26 T 01-11-2018 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain MLA2C4_23330 d2f3d947dd0198012e4e30e58045a78f 204 Gene3D G3DSA:2.30.29.50 12 115 1.9E-46 T 01-11-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily MLA2C4_23330 d2f3d947dd0198012e4e30e58045a78f 204 Gene3D G3DSA:1.10.287.210 116 204 3.3E-36 T 01-11-2018 MLA2C4_23330 d2f3d947dd0198012e4e30e58045a78f 204 Pfam PF08000 Bacterial PH domain 11 131 1.2E-36 T 01-11-2018 IPR012544 Bacterial Pleckstrin homology domain MLA2C4_12115 4f641feca37c647c303ec2ef93b1cae5 478 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 11 478 4.6E-284 T 01-11-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 MLA2C4_12115 4f641feca37c647c303ec2ef93b1cae5 478 Pfam PF03972 MmgE/PrpD family 15 462 1.7E-153 T 01-11-2018 IPR005656 MmgE/PrpD GO:0016829 MLA2C4_12115 4f641feca37c647c303ec2ef93b1cae5 478 SUPERFAMILY SSF103378 11 476 3.01E-161 T 01-11-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 MLA2C4_12115 4f641feca37c647c303ec2ef93b1cae5 478 Gene3D G3DSA:3.30.1330.120 283 421 1.8E-194 T 01-11-2018 MLA2C4_12115 4f641feca37c647c303ec2ef93b1cae5 478 Gene3D G3DSA:1.10.4100.10 20 456 1.8E-194 T 01-11-2018 MLA2C4_01905 7b0f9643e64c3c763a143ce1c4f5f789 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.4E-22 T 01-11-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MLA2C4_01905 7b0f9643e64c3c763a143ce1c4f5f789 96 Gene3D G3DSA:1.10.20.60 2 94 6.6E-32 T 01-11-2018 MLA2C4_01905 7b0f9643e64c3c763a143ce1c4f5f789 96 SUPERFAMILY SSF141000 4 94 5.62E-32 T 01-11-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 MLA2C4_01905 7b0f9643e64c3c763a143ce1c4f5f789 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.1E-33 T 01-11-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MLA2C4_01905 7b0f9643e64c3c763a143ce1c4f5f789 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.744 T 01-11-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 MLA2C4_14325 34c856a91d78046322fd7f4ea6222efc 123 Pfam PF14176 YxiJ-like protein 9 118 4.8E-49 T 01-11-2018 IPR025551 Immunity protein WapI-like MLA2C4_15050 06d4723a52b741a1042f4e8eb1c1bc12 393 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 7 390 2.3E-138 T 01-11-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes MLA2C4_15050 06d4723a52b741a1042f4e8eb1c1bc12 393 Pfam PF04914 DltD protein 41 390 6.7E-123 T 01-11-2018 IPR006998 DltD MLA2C4_15050 06d4723a52b741a1042f4e8eb1c1bc12 393 PIRSF PIRSF021438 1 393 1.5E-160 T 01-11-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes MLA2C4_15050 06d4723a52b741a1042f4e8eb1c1bc12 393 Gene3D G3DSA:3.40.50.1110 257 393 1.7E-5 T 01-11-2018 IPR036514 SGNH hydrolase superfamily MLA2C4_15050 06d4723a52b741a1042f4e8eb1c1bc12 393 SUPERFAMILY SSF52266 221 392 1.41E-17 T 01-11-2018 MLA2C4_16255 ec39c0017338708ec03c9f72edd6e08b 210 Pfam PF02698 DUF218 domain 48 177 7.1E-27 T 01-11-2018 IPR003848 Domain of unknown function DUF218 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 Pfam PF00465 Iron-containing alcohol dehydrogenase 464 851 1.1E-120 T 01-11-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 Gene3D G3DSA:3.40.50.1970 457 649 1.9E-64 T 01-11-2018 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 SUPERFAMILY SSF56796 455 866 1.96E-126 T 01-11-2018 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 SUPERFAMILY SSF53720 16 460 3.27E-81 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 Gene3D G3DSA:1.20.1090.10 651 867 2.1E-71 T 01-11-2018 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 PIRSF PIRSF000111 1 867 0.0 T 01-11-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 Pfam PF00171 Aldehyde dehydrogenase family 13 408 1.1E-23 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 Gene3D G3DSA:3.40.309.10 227 412 1.3E-182 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 Gene3D G3DSA:3.40.605.10 19 451 1.3E-182 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_22805 029ba4d4f2d9fafeca58481b0e43725c 867 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 638 666 - T 01-11-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MLA2C4_19155 f44fce932d75be83981a46c4606e4ae9 146 Gene3D G3DSA:3.30.310.250 1 145 2.4E-41 T 01-11-2018 IPR038449 SirA superfamily MLA2C4_19155 f44fce932d75be83981a46c4606e4ae9 146 Pfam PF10747 Sporulation inhibitor of replication protein SirA 2 140 1.5E-41 T 01-11-2018 IPR019683 Sporulation inhibitor of replication protein SirA MLA2C4_14355 886b31ff47db74fe096474a74fa2588c 440 SUPERFAMILY SSF51905 4 353 3.18E-26 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14355 886b31ff47db74fe096474a74fa2588c 440 Pfam PF12831 FAD dependent oxidoreductase 6 396 5.2E-9 T 01-11-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal MLA2C4_14355 886b31ff47db74fe096474a74fa2588c 440 Gene3D G3DSA:3.50.50.60 3 416 2.7E-19 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_27415 8a26547e027b9d6f8ef3d2e960f03cde 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 15 332 25.095 T 01-11-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27415 8a26547e027b9d6f8ef3d2e960f03cde 333 Pfam PF00146 NADH dehydrogenase 23 326 1.0E-124 T 01-11-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27415 8a26547e027b9d6f8ef3d2e960f03cde 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 01-11-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_10600 01ceedbd4c77d378f95b151fbd63add1 140 Gene3D G3DSA:3.40.630.30 2 140 6.5E-24 T 01-11-2018 MLA2C4_10600 01ceedbd4c77d378f95b151fbd63add1 140 SUPERFAMILY SSF55729 7 134 1.05E-19 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10600 01ceedbd4c77d378f95b151fbd63add1 140 Pfam PF00583 Acetyltransferase (GNAT) family 30 129 3.6E-15 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10260 f57bdba8d176ea45881059544e9f0b1e 314 SUPERFAMILY SSF53474 123 306 1.09E-22 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_10260 f57bdba8d176ea45881059544e9f0b1e 314 Pfam PF02230 Phospholipase/Carboxylesterase 195 306 2.2E-6 T 01-11-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MLA2C4_10260 f57bdba8d176ea45881059544e9f0b1e 314 Gene3D G3DSA:3.40.50.1820 103 311 5.2E-19 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_17550 9c7fe4a2fda11360124099341990a549 187 SMART SM01266 5 59 6.7E-19 T 01-11-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MLA2C4_17550 9c7fe4a2fda11360124099341990a549 187 Pfam PF12464 Maltose acetyltransferase 7 56 6.5E-15 T 01-11-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MLA2C4_17550 9c7fe4a2fda11360124099341990a549 187 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_17550 9c7fe4a2fda11360124099341990a549 187 Gene3D G3DSA:2.160.10.10 1 187 1.7E-76 T 01-11-2018 MLA2C4_17550 9c7fe4a2fda11360124099341990a549 187 SUPERFAMILY SSF51161 1 185 2.63E-53 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_17550 9c7fe4a2fda11360124099341990a549 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 131 166 7.6E-10 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_17240 d09e3df043eab6cd15010f36f4e98555 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 9.4E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_17240 d09e3df043eab6cd15010f36f4e98555 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 9.4E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_17240 d09e3df043eab6cd15010f36f4e98555 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 9.4E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_17240 d09e3df043eab6cd15010f36f4e98555 305 SUPERFAMILY SSF53474 8 304 8.51E-62 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_17240 d09e3df043eab6cd15010f36f4e98555 305 Pfam PF00561 alpha/beta hydrolase fold 35 289 3.4E-28 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_17240 d09e3df043eab6cd15010f36f4e98555 305 Gene3D G3DSA:3.40.50.1820 15 304 4.6E-60 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12645 ee6c65d6d0008aa973e9901938c6c353 396 Pfam PF01580 FtsK/SpoIIIE family 132 244 2.9E-15 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_12645 ee6c65d6d0008aa973e9901938c6c353 396 SUPERFAMILY SSF52540 129 366 1.42E-12 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12645 ee6c65d6d0008aa973e9901938c6c353 396 Gene3D G3DSA:3.40.50.300 111 382 2.9E-45 T 01-11-2018 MLA2C4_23850 11d047102fb29bd5e325c06684aa8051 157 SUPERFAMILY SSF54637 8 144 8.33E-24 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_23850 11d047102fb29bd5e325c06684aa8051 157 Pfam PF01575 MaoC like domain 24 124 6.1E-9 T 01-11-2018 IPR002539 MaoC-like dehydratase domain MLA2C4_23850 11d047102fb29bd5e325c06684aa8051 157 Gene3D G3DSA:3.10.129.10 9 157 5.7E-28 T 01-11-2018 MLA2C4_15840 aad325edb7932f693d811e9b2bef4868 180 SUPERFAMILY SSF55729 3 175 2.88E-54 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15840 aad325edb7932f693d811e9b2bef4868 180 Gene3D G3DSA:3.40.630.30 3 180 4.0E-52 T 01-11-2018 MLA2C4_15840 aad325edb7932f693d811e9b2bef4868 180 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 1.6E-33 T 01-11-2018 IPR000182 GNAT domain MLA2C4_11275 3ad09ff5fec1a94b1f98bf0ad3ba6ca5 284 SMART SM00014 53 162 1.2E-13 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_11275 3ad09ff5fec1a94b1f98bf0ad3ba6ca5 284 Pfam PF01569 PAP2 superfamily 52 165 4.2E-21 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_11275 3ad09ff5fec1a94b1f98bf0ad3ba6ca5 284 SUPERFAMILY SSF48317 1 165 2.22E-32 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_11275 3ad09ff5fec1a94b1f98bf0ad3ba6ca5 284 Gene3D G3DSA:1.20.144.10 84 173 8.9E-17 T 01-11-2018 MLA2C4_00405 a72b841f3f22ba7de04ddb21204992d6 286 Gene3D G3DSA:3.20.20.20 10 286 1.5E-119 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_00405 a72b841f3f22ba7de04ddb21204992d6 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 31 46 - T 01-11-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_00405 a72b841f3f22ba7de04ddb21204992d6 286 SUPERFAMILY SSF51717 18 282 2.09E-102 T 01-11-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_00405 a72b841f3f22ba7de04ddb21204992d6 286 Pfam PF00809 Pterin binding enzyme 32 265 1.1E-87 T 01-11-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_00405 a72b841f3f22ba7de04ddb21204992d6 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 31 280 1.9E-100 T 01-11-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MLA2C4_00405 a72b841f3f22ba7de04ddb21204992d6 286 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 65 78 - T 01-11-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MLA2C4_19320 038fd2cb82e50373cb8c587a0001cdee 297 SUPERFAMILY SSF53448 4 233 4.81E-32 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_19320 038fd2cb82e50373cb8c587a0001cdee 297 Gene3D G3DSA:3.90.550.10 2 259 4.2E-28 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_19320 038fd2cb82e50373cb8c587a0001cdee 297 Pfam PF00535 Glycosyl transferase family 2 5 134 1.5E-23 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_07075 ec4c5dd0727778bd2410422f487e1653 93 SUPERFAMILY SSF140500 9 61 1.44E-14 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_07075 ec4c5dd0727778bd2410422f487e1653 93 Pfam PF09388 Spo0E like sporulation regulatory protein 13 54 5.4E-14 T 01-11-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 MLA2C4_07075 ec4c5dd0727778bd2410422f487e1653 93 Gene3D G3DSA:1.20.58.990 8 66 7.0E-13 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 Gene3D G3DSA:3.30.465.10 91 217 1.3E-43 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 SUPERFAMILY SSF56194 200 302 1.05E-37 T 01-11-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 301 3.1E-78 T 01-11-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 SUPERFAMILY SSF56176 3 194 2.25E-48 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 305 95.943 T 01-11-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 300 8.7E-30 T 01-11-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 Pfam PF01565 FAD binding domain 38 166 3.5E-27 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 Gene3D G3DSA:3.30.43.10 1 89 5.1E-27 T 01-11-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MLA2C4_26390 5e3860724a13368bb068bd611d0a438c 305 Gene3D G3DSA:3.90.78.10 218 305 5.1E-35 T 01-11-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_06545 457681fe7cd525aef503c79aba91fa82 261 Pfam PF13240 zinc-ribbon domain 2 24 8.3E-6 T 01-11-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 MLA2C4_06545 457681fe7cd525aef503c79aba91fa82 261 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 1 129 0.002 T 01-11-2018 MLA2C4_23620 d0c4522d9f9a1c769bc5e1143a9fab19 327 Gene3D G3DSA:1.10.3470.10 2 325 4.1E-87 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_23620 d0c4522d9f9a1c769bc5e1143a9fab19 327 Pfam PF01032 FecCD transport family 14 320 1.1E-87 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_23620 d0c4522d9f9a1c769bc5e1143a9fab19 327 SUPERFAMILY SSF81345 3 320 7.98E-76 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 184 194 - T 01-11-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 Hamap MF_00258 Glutamate racemase [murI]. 8 259 37.744 T 01-11-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 TIGRFAM TIGR00067 glut_race: glutamate racemase 10 256 1.1E-79 T 01-11-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 217 2.2E-37 T 01-11-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 SUPERFAMILY SSF53681 10 111 1.28E-34 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 Gene3D G3DSA:3.40.50.1860 10 256 1.3E-94 T 01-11-2018 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 SUPERFAMILY SSF53681 114 264 1.8E-37 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_04630 5974d8350482f15c1e166e522237751b 278 Gene3D G3DSA:3.40.50.1860 99 211 1.3E-94 T 01-11-2018 MLA2C4_04850 1774beb500277c651bcff10be5ef57f3 349 SUPERFAMILY SSF53187 6 343 1.09E-55 T 01-11-2018 MLA2C4_04850 1774beb500277c651bcff10be5ef57f3 349 PIRSF PIRSF001123 5 344 4.8E-43 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_04850 1774beb500277c651bcff10be5ef57f3 349 Gene3D G3DSA:3.40.630.10 14 342 1.7E-134 T 01-11-2018 MLA2C4_04850 1774beb500277c651bcff10be5ef57f3 349 Pfam PF05343 M42 glutamyl aminopeptidase 49 337 6.0E-91 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_04850 1774beb500277c651bcff10be5ef57f3 349 SUPERFAMILY SSF101821 74 186 4.43E-33 T 01-11-2018 MLA2C4_04850 1774beb500277c651bcff10be5ef57f3 349 Gene3D G3DSA:2.40.30.40 77 171 1.7E-134 T 01-11-2018 IPR023367 Peptidase M42, domain 2 MLA2C4_17025 d1ddf1dd4f8e4bd73422db51f09f99cb 419 Pfam PF05977 Transmembrane secretion effector 4 405 8.1E-24 T 01-11-2018 IPR010290 Transmembrane secretion effector MLA2C4_17025 d1ddf1dd4f8e4bd73422db51f09f99cb 419 Gene3D G3DSA:1.20.1250.20 2 388 1.2E-23 T 01-11-2018 MLA2C4_17025 d1ddf1dd4f8e4bd73422db51f09f99cb 419 SUPERFAMILY SSF103473 5 391 2.22E-33 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 Pfam PF00005 ABC transporter 358 507 5.6E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 SMART SM00382 367 553 1.0E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 Gene3D G3DSA:3.40.50.300 331 583 1.8E-91 T 01-11-2018 MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 Pfam PF00664 ABC transporter transmembrane region 20 294 1.7E-39 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 SUPERFAMILY SSF52540 332 578 1.93E-95 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 SUPERFAMILY SSF90123 5 324 6.67E-78 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_02740 9021a7c3fd9fd96e695d52b820cf9bbe 586 Gene3D G3DSA:1.20.1560.10 4 324 2.0E-110 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_07485 0f3182ff021772a9edf4d78fb9b6852a 233 Gene3D G3DSA:1.20.120.1760 3 172 4.4E-12 T 01-11-2018 MLA2C4_07485 0f3182ff021772a9edf4d78fb9b6852a 233 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MLA2C4_07485 0f3182ff021772a9edf4d78fb9b6852a 233 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 3.5E-13 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MLA2C4_07485 0f3182ff021772a9edf4d78fb9b6852a 233 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 168 1.1E-39 T 01-11-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MLA2C4_25820 59db1db68c4c6500bf30f92f2971be01 323 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 322 1.1E-128 T 01-11-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MLA2C4_25820 59db1db68c4c6500bf30f92f2971be01 323 PIRSF PIRSF004532 1 322 2.8E-150 T 01-11-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MLA2C4_25820 59db1db68c4c6500bf30f92f2971be01 323 SUPERFAMILY SSF56655 2 314 6.41E-106 T 01-11-2018 MLA2C4_25820 59db1db68c4c6500bf30f92f2971be01 323 Gene3D G3DSA:3.40.190.90 122 284 2.0E-134 T 01-11-2018 MLA2C4_25820 59db1db68c4c6500bf30f92f2971be01 323 Gene3D G3DSA:3.30.540.10 7 311 2.0E-134 T 01-11-2018 MLA2C4_25820 59db1db68c4c6500bf30f92f2971be01 323 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 311 3.3E-142 T 01-11-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 MLA2C4_22010 83a5cef8d6b6063f37a04a664402a5d0 223 SUPERFAMILY SSF158560 2 97 1.31E-30 T 01-11-2018 MLA2C4_22010 83a5cef8d6b6063f37a04a664402a5d0 223 SUPERFAMILY SSF103473 96 216 5.89E-5 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_22010 83a5cef8d6b6063f37a04a664402a5d0 223 Pfam PF06570 Protein of unknown function (DUF1129) 33 222 4.8E-8 T 01-11-2018 IPR009214 Protein of unknown function DUF1129 MLA2C4_04325 ee1dec41969fffe07938300716252888 551 Gene3D G3DSA:1.20.58.220 450 546 6.6E-23 T 01-11-2018 IPR038078 PhoU-like domain superfamily MLA2C4_04325 ee1dec41969fffe07938300716252888 551 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 9 316 9.8E-75 T 01-11-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 MLA2C4_04325 ee1dec41969fffe07938300716252888 551 SUPERFAMILY SSF109755 336 539 1.57E-48 T 01-11-2018 MLA2C4_04325 ee1dec41969fffe07938300716252888 551 Pfam PF01895 PhoU domain 453 536 5.4E-19 T 01-11-2018 IPR026022 PhoU domain MLA2C4_04325 ee1dec41969fffe07938300716252888 551 Pfam PF01895 PhoU domain 348 434 1.2E-11 T 01-11-2018 IPR026022 PhoU domain MLA2C4_04325 ee1dec41969fffe07938300716252888 551 Gene3D G3DSA:1.20.58.220 338 446 7.4E-14 T 01-11-2018 IPR038078 PhoU-like domain superfamily MLA2C4_04325 ee1dec41969fffe07938300716252888 551 Pfam PF02690 Na+/Pi-cotransporter 151 253 1.9E-18 T 01-11-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MLA2C4_04325 ee1dec41969fffe07938300716252888 551 Pfam PF02690 Na+/Pi-cotransporter 18 153 8.5E-51 T 01-11-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MLA2C4_10970 f85d9e832821dafaabd5fc3ec1108589 127 Pfam PF04134 Protein of unknown function, DUF393 3 109 6.6E-16 T 01-11-2018 IPR007263 Protein of unknown function DUF393 MLA2C4_10970 f85d9e832821dafaabd5fc3ec1108589 127 SUPERFAMILY SSF52833 2 77 4.82E-7 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_02365 31d34e1ecede8b9ac7c9c98232ee2538 83 SMART SM00530 23 78 2.3E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_02365 31d34e1ecede8b9ac7c9c98232ee2538 83 Gene3D G3DSA:1.10.260.40 20 82 8.5E-26 T 01-11-2018 MLA2C4_02365 31d34e1ecede8b9ac7c9c98232ee2538 83 SUPERFAMILY SSF47413 21 81 1.32E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_02365 31d34e1ecede8b9ac7c9c98232ee2538 83 Pfam PF01381 Helix-turn-helix 24 78 3.3E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 10 138 1.1E-38 T 01-11-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 4.3E-27 T 01-11-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 4.3E-27 T 01-11-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 4.3E-27 T 01-11-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 4.3E-27 T 01-11-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 4.3E-27 T 01-11-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 Gene3D G3DSA:2.40.100.10 1 145 1.4E-57 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 PIRSF PIRSF001467 6 145 5.1E-40 T 01-11-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 SUPERFAMILY SSF50891 14 138 5.99E-46 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_21250 9a2d3d704b6430d2cac14c6bcc40b9ad 145 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 01-11-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MLA2C4_10090 aa78ae84ac35c583c32642842c218c97 84 Gene3D G3DSA:1.10.1200.10 5 83 3.3E-13 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_10090 aa78ae84ac35c583c32642842c218c97 84 SUPERFAMILY SSF47336 3 81 2.3E-11 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_18100 dc9ab0ed789316c08618a3f1b9de8de1 170 Pfam PF10901 Protein of unknown function (DUF2690) 36 147 2.0E-27 T 01-11-2018 IPR021224 Protein of unknown function DUF2690 MLA2C4_12410 3473ccbaec794f052b2036ee51fca916 170 Gene3D G3DSA:3.40.630.30 2 162 1.5E-36 T 01-11-2018 MLA2C4_12410 3473ccbaec794f052b2036ee51fca916 170 Pfam PF00583 Acetyltransferase (GNAT) family 44 135 3.0E-19 T 01-11-2018 IPR000182 GNAT domain MLA2C4_12410 3473ccbaec794f052b2036ee51fca916 170 SUPERFAMILY SSF55729 3 160 6.52E-34 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_02375 86db4c77bdf7940ab0dbcdbcb08b378e 427 SUPERFAMILY SSF103473 16 412 7.32E-37 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_02375 86db4c77bdf7940ab0dbcdbcb08b378e 427 Gene3D G3DSA:1.20.1250.20 225 415 7.2E-19 T 01-11-2018 MLA2C4_02375 86db4c77bdf7940ab0dbcdbcb08b378e 427 Gene3D G3DSA:1.20.1250.20 11 203 4.2E-7 T 01-11-2018 MLA2C4_02375 86db4c77bdf7940ab0dbcdbcb08b378e 427 Pfam PF11700 Vacuole effluxer Atg22 like 138 411 5.1E-49 T 01-11-2018 IPR024671 Autophagy-related protein 22-like MLA2C4_02375 86db4c77bdf7940ab0dbcdbcb08b378e 427 Pfam PF11700 Vacuole effluxer Atg22 like 9 131 1.2E-10 T 01-11-2018 IPR024671 Autophagy-related protein 22-like MLA2C4_06510 3c3fe4799f96bf53420b9b8530006c92 204 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 202 39.457 T 01-11-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MLA2C4_06510 3c3fe4799f96bf53420b9b8530006c92 204 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 196 1.2E-52 T 01-11-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MLA2C4_06510 3c3fe4799f96bf53420b9b8530006c92 204 Gene3D G3DSA:3.20.20.70 1 202 1.3E-70 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_06510 3c3fe4799f96bf53420b9b8530006c92 204 SUPERFAMILY SSF51366 1 199 3.92E-57 T 01-11-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 SMART SM00279 175 210 2.5E-14 T 01-11-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 SUPERFAMILY SSF88723 1 172 1.13E-47 T 01-11-2018 IPR029060 PIN-like domain superfamily MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 SUPERFAMILY SSF47807 173 278 2.69E-26 T 01-11-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 260 3.2E-26 T 01-11-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 170 2.9E-51 T 01-11-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 Gene3D G3DSA:3.40.50.1010 4 277 3.1E-86 T 01-11-2018 MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 Gene3D G3DSA:1.10.150.20 176 248 3.1E-86 T 01-11-2018 MLA2C4_08305 a32d7e234373d3e3b2579577a1461218 288 SMART SM00475 2 263 1.1E-109 T 01-11-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MLA2C4_09650 175b0377a7535c862ebf1d23cd05cc01 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 65 5.5E-24 T 01-11-2018 IPR009242 Protein of unknown function DUF896 MLA2C4_09650 175b0377a7535c862ebf1d23cd05cc01 76 Gene3D G3DSA:1.10.287.540 1 57 6.6E-17 T 01-11-2018 MLA2C4_09650 175b0377a7535c862ebf1d23cd05cc01 76 Hamap MF_01103 UPF0291 protein . 1 58 13.871 T 01-11-2018 IPR009242 Protein of unknown function DUF896 MLA2C4_09650 175b0377a7535c862ebf1d23cd05cc01 76 SUPERFAMILY SSF158221 1 40 3.92E-12 T 01-11-2018 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 Pfam PF01235 Sodium:alanine symporter family 56 450 3.3E-158 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 PRINTS PR00175 Sodium/alanine symporter signature 211 230 4.5E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 PRINTS PR00175 Sodium/alanine symporter signature 183 201 4.5E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 PRINTS PR00175 Sodium/alanine symporter signature 302 320 4.5E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 PRINTS PR00175 Sodium/alanine symporter signature 407 427 4.5E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 PRINTS PR00175 Sodium/alanine symporter signature 93 115 4.5E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 PRINTS PR00175 Sodium/alanine symporter signature 347 369 4.5E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26340 686efcba25d72114093bd88e332c3b6e 476 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 2.4E-155 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_09995 ece26ac0ea1b70265f2ca1e1d6b8ce04 112 Pfam PF13630 SdpI/YhfL protein family 31 97 4.6E-15 T 01-11-2018 IPR025962 SdpI/YhfL protein family MLA2C4_28330 57e9957ac941633fdfc0357eddfbb6ae 264 Gene3D G3DSA:3.60.15.10 9 249 1.1E-41 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_28330 57e9957ac941633fdfc0357eddfbb6ae 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 6.1E-22 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_28330 57e9957ac941633fdfc0357eddfbb6ae 264 SMART SM00849 13 193 5.4E-13 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_28330 57e9957ac941633fdfc0357eddfbb6ae 264 SUPERFAMILY SSF56281 3 241 2.23E-45 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 Gene3D G3DSA:1.10.10.10 133 232 1.8E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 Gene3D G3DSA:3.40.50.2300 1 132 1.4E-37 T 01-11-2018 MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 SUPERFAMILY SSF52172 3 130 9.25E-41 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 SMART SM00448 4 114 7.3E-43 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 SUPERFAMILY SSF46894 135 230 6.8E-27 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 SMART SM00862 154 230 8.3E-25 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 Pfam PF00072 Response regulator receiver domain 6 114 7.8E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09555 29591a176459337295aac63a386c8cc8 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 4.2E-25 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_00105 4679cd756369ae6cc2644c0788016c86 211 Gene3D G3DSA:3.40.50.300 5 207 1.3E-46 T 01-11-2018 MLA2C4_00105 4679cd756369ae6cc2644c0788016c86 211 PIRSF PIRSF000705 2 210 2.5E-56 T 01-11-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 MLA2C4_00105 4679cd756369ae6cc2644c0788016c86 211 Pfam PF01712 Deoxynucleoside kinase 7 204 1.5E-45 T 01-11-2018 IPR031314 Deoxynucleoside kinase domain MLA2C4_00105 4679cd756369ae6cc2644c0788016c86 211 SUPERFAMILY SSF52540 5 205 1.7E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 SUPERFAMILY SSF46894 7 72 4.76E-23 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 Gene3D G3DSA:1.10.10.10 1 74 8.0E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 SMART SM00421 9 66 4.9E-25 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 2.6E-12 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 2.6E-12 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 2.6E-12 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_23405 cb8957cb8654812e171c05b44751e641 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 6.3E-24 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_17870 a782fcf670d51e18e7466c7fee18c382 210 PIRSF PIRSF006324 1 209 4.2E-48 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_17870 a782fcf670d51e18e7466c7fee18c382 210 Pfam PF01810 LysE type translocator 15 206 6.5E-35 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_08990 7e5432d46ef0ae429c676213c06cd3c5 261 Gene3D G3DSA:3.60.15.10 5 242 3.4E-43 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_08990 7e5432d46ef0ae429c676213c06cd3c5 261 Pfam PF00753 Metallo-beta-lactamase superfamily 30 192 2.8E-15 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_08990 7e5432d46ef0ae429c676213c06cd3c5 261 SUPERFAMILY SSF56281 7 239 6.02E-41 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_08990 7e5432d46ef0ae429c676213c06cd3c5 261 SMART SM00849 29 219 3.6E-28 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_11310 e43222730522722c0d34f689e9ca94cb 297 SUPERFAMILY SSF82689 171 281 3.92E-10 T 01-11-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MLA2C4_11310 e43222730522722c0d34f689e9ca94cb 297 SUPERFAMILY SSF82861 22 104 1.83E-11 T 01-11-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MLA2C4_11310 e43222730522722c0d34f689e9ca94cb 297 Gene3D G3DSA:3.30.70.100 173 271 3.1E-9 T 01-11-2018 MLA2C4_11310 e43222730522722c0d34f689e9ca94cb 297 Gene3D G3DSA:2.30.30.60 121 171 1.5E-17 T 01-11-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MLA2C4_11310 e43222730522722c0d34f689e9ca94cb 297 SUPERFAMILY SSF50182 106 169 7.85E-10 T 01-11-2018 IPR010920 LSM domain superfamily MLA2C4_11310 e43222730522722c0d34f689e9ca94cb 297 Pfam PF00924 Mechanosensitive ion channel 65 272 6.8E-33 T 01-11-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 311 322 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 453 6.5E-206 T 01-11-2018 IPR004452 4Fe-4S binding protein GO:0019516 MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 Pfam PF13183 4Fe-4S dicluster domain 309 375 2.9E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 SUPERFAMILY SSF46548 280 391 3.49E-17 T 01-11-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 473 65.044 T 01-11-2018 IPR022825 Lactate utilization protein B MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 Pfam PF02589 LUD domain 71 293 3.2E-54 T 01-11-2018 IPR003741 LUD domain MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 Gene3D G3DSA:3.40.50.10420 131 293 2.6E-11 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 SUPERFAMILY SSF100950 64 294 3.01E-36 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_06930 dc828d13e3ed3345dba3b3c7befad30d 473 Pfam PF11870 Domain of unknown function (DUF3390) 383 469 5.1E-22 T 01-11-2018 IPR024569 4Fe-4S binding protein, C-terminal MLA2C4_14585 79470ab98c7ae59ec507b731b99f4b5b 446 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 438 1.2E-148 T 01-11-2018 IPR014239 Spore germination YpeB GO:0009847 MLA2C4_14585 79470ab98c7ae59ec507b731b99f4b5b 446 Pfam PF14620 YpeB sporulation 14 372 1.7E-137 T 01-11-2018 IPR014239 Spore germination YpeB GO:0009847 MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.7E-31 T 01-11-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 SUPERFAMILY SSF54211 80 159 3.79E-26 T 01-11-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 7.8E-73 T 01-11-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 Gene3D G3DSA:3.30.230.10 74 166 2.3E-37 T 01-11-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 SUPERFAMILY SSF54768 9 76 1.36E-25 T 01-11-2018 MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.021 T 01-11-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 01-11-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 4.2E-33 T 01-11-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MLA2C4_00760 3149f812515dc415e17f9e6c3d36ddcc 166 Gene3D G3DSA:3.30.160.20 1 73 6.4E-36 T 01-11-2018 MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 SUPERFAMILY SSF46689 12 96 9.75E-18 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 7.8E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 7.8E-8 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 SUPERFAMILY SSF48498 121 205 9.56E-7 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 Gene3D G3DSA:1.10.10.60 12 65 1.6E-16 T 01-11-2018 MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 Gene3D G3DSA:1.10.357.10 66 207 8.5E-13 T 01-11-2018 MLA2C4_12385 d1507eeacd14ecd5fccfd8372cf3f723 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 9.1E-14 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 Gene3D G3DSA:1.20.1720.10 19 398 1.9E-106 T 01-11-2018 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 SUPERFAMILY SSF103473 9 404 3.14E-70 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 17 398 4.8E-107 T 01-11-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 PRINTS PR01035 Tetracycline resistance protein signature 86 110 7.7E-8 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 PRINTS PR01035 Tetracycline resistance protein signature 286 307 7.7E-8 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 PRINTS PR01035 Tetracycline resistance protein signature 29 45 7.7E-8 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 PRINTS PR01035 Tetracycline resistance protein signature 173 193 7.7E-8 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 PRINTS PR01035 Tetracycline resistance protein signature 113 134 7.7E-8 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_01055 92c65858b9b6aa70dfc62e3de70a4ff3 416 Pfam PF07690 Major Facilitator Superfamily 26 365 3.0E-47 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_23415 133d605de7c36e5a719598c633d67fc0 413 Gene3D G3DSA:2.30.40.10 28 400 2.5E-115 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_23415 133d605de7c36e5a719598c633d67fc0 413 Pfam PF07969 Amidohydrolase family 55 401 1.4E-36 T 01-11-2018 IPR013108 Amidohydrolase 3 MLA2C4_23415 133d605de7c36e5a719598c633d67fc0 413 Gene3D G3DSA:3.20.20.140 66 360 2.5E-115 T 01-11-2018 MLA2C4_23415 133d605de7c36e5a719598c633d67fc0 413 SUPERFAMILY SSF51556 66 370 3.72E-73 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_22815 c8636bfe0d679b90d9b53fcc5c0c29a1 307 Gene3D G3DSA:3.40.50.1100 9 299 1.0E-112 T 01-11-2018 MLA2C4_22815 c8636bfe0d679b90d9b53fcc5c0c29a1 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 01-11-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MLA2C4_22815 c8636bfe0d679b90d9b53fcc5c0c29a1 307 SUPERFAMILY SSF53686 2 305 1.7E-90 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_22815 c8636bfe0d679b90d9b53fcc5c0c29a1 307 Gene3D G3DSA:3.40.50.1100 45 146 1.0E-112 T 01-11-2018 MLA2C4_22815 c8636bfe0d679b90d9b53fcc5c0c29a1 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 1.1E-62 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_14605 0b58724cfb362e0ede7e8b58fed5acde 279 Gene3D G3DSA:1.20.58.480 20 279 3.3E-102 T 01-11-2018 MLA2C4_14605 0b58724cfb362e0ede7e8b58fed5acde 279 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 17 279 41.664 T 01-11-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MLA2C4_14605 0b58724cfb362e0ede7e8b58fed5acde 279 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 16 279 4.7E-132 T 01-11-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 MLA2C4_14605 0b58724cfb362e0ede7e8b58fed5acde 279 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 146 1.0E-43 T 01-11-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MLA2C4_14605 0b58724cfb362e0ede7e8b58fed5acde 279 Pfam PF03301 Tryptophan 2,3-dioxygenase 164 278 1.2E-26 T 01-11-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MLA2C4_14605 0b58724cfb362e0ede7e8b58fed5acde 279 SUPERFAMILY SSF140959 22 279 2.62E-103 T 01-11-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MLA2C4_09860 b0eb5b1a78dd3a7c66ceb5f200a2d7b0 351 Gene3D G3DSA:3.20.20.30 5 351 3.4E-67 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_09860 b0eb5b1a78dd3a7c66ceb5f200a2d7b0 351 Pfam PF00296 Luciferase-like monooxygenase 24 308 1.1E-41 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MLA2C4_09860 b0eb5b1a78dd3a7c66ceb5f200a2d7b0 351 SUPERFAMILY SSF51679 13 347 6.93E-65 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_18050 b5302bd673a8369068dad9988aad0a8e 183 Pfam PF13302 Acetyltransferase (GNAT) domain 13 150 4.3E-16 T 01-11-2018 IPR000182 GNAT domain MLA2C4_18050 b5302bd673a8369068dad9988aad0a8e 183 SUPERFAMILY SSF55729 1 175 3.06E-34 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_18050 b5302bd673a8369068dad9988aad0a8e 183 Gene3D G3DSA:3.40.630.30 1 181 2.0E-40 T 01-11-2018 MLA2C4_07595 7e6b4f5adfb55889f1200c05e8e91262 351 SUPERFAMILY SSF55874 220 342 1.19E-17 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07595 7e6b4f5adfb55889f1200c05e8e91262 351 SMART SM00387 252 345 4.3E-10 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07595 7e6b4f5adfb55889f1200c05e8e91262 351 Gene3D G3DSA:3.30.565.10 214 346 2.5E-30 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_07595 7e6b4f5adfb55889f1200c05e8e91262 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 342 3.6E-6 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_07595 7e6b4f5adfb55889f1200c05e8e91262 351 Pfam PF07730 Histidine kinase 149 216 6.7E-20 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_07595 7e6b4f5adfb55889f1200c05e8e91262 351 PIRSF PIRSF037431 5 351 6.9E-137 T 01-11-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 MLA2C4_05120 407c306312036909a3e339186616a882 194 Gene3D G3DSA:1.20.120.1760 1 181 2.6E-16 T 01-11-2018 MLA2C4_05120 407c306312036909a3e339186616a882 194 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 178 3.1E-54 T 01-11-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MLA2C4_05120 407c306312036909a3e339186616a882 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 21 84 7.1E-15 T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MLA2C4_05120 407c306312036909a3e339186616a882 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 62 84 - T 01-11-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MLA2C4_18520 687afdd86ae0ca2203180de46455fce7 259 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 77 86 - T 01-11-2018 IPR024002 Formate/nitrite transporter, conserved site MLA2C4_18520 687afdd86ae0ca2203180de46455fce7 259 Pfam PF01226 Formate/nitrite transporter 8 248 3.5E-72 T 01-11-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_18520 687afdd86ae0ca2203180de46455fce7 259 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 161 171 - T 01-11-2018 IPR024002 Formate/nitrite transporter, conserved site MLA2C4_18520 687afdd86ae0ca2203180de46455fce7 259 Gene3D G3DSA:1.20.1080.10 4 259 9.8E-77 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_21290 4739c16097249537c3a7b16ae92f3eae 138 Pfam PF13782 Stage V sporulation protein AB 26 134 4.4E-35 T 01-11-2018 IPR020144 Stage V sporulation protein AB MLA2C4_21290 4739c16097249537c3a7b16ae92f3eae 138 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 22 138 5.0E-56 T 01-11-2018 IPR020144 Stage V sporulation protein AB MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 Gene3D G3DSA:1.20.210.10 28 559 1.9E-198 T 01-11-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 SUPERFAMILY SSF81442 48 573 3.92E-175 T 01-11-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 318 333 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 114 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 210 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 272 293 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 44 69 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 118 142 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 221 240 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 377 395 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 160 172 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 342 363 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 405 424 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 PRINTS PR01165 Cytochrome c oxidase subunit I signature 455 476 1.6E-98 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 2 642 0.0 T 01-11-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 274 328 - T 01-11-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_03695 ea50469bd75a0ef88396f539bbfc8f97 644 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 53 499 6.9E-142 T 01-11-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_10615 2aa25016c012cb45abcef5dce1862737 188 SUPERFAMILY SSF55729 3 177 2.3E-38 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10615 2aa25016c012cb45abcef5dce1862737 188 Gene3D G3DSA:3.40.630.30 1 186 6.5E-38 T 01-11-2018 MLA2C4_10615 2aa25016c012cb45abcef5dce1862737 188 Pfam PF13302 Acetyltransferase (GNAT) domain 11 152 1.6E-20 T 01-11-2018 IPR000182 GNAT domain MLA2C4_20060 493aa6ad48d69a4ed4189ce09aafa338 296 SUPERFAMILY SSF52540 9 192 2.06E-47 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20060 493aa6ad48d69a4ed4189ce09aafa338 296 Gene3D G3DSA:1.10.1580.10 180 272 4.1E-31 T 01-11-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily MLA2C4_20060 493aa6ad48d69a4ed4189ce09aafa338 296 Gene3D G3DSA:3.40.50.300 12 179 2.9E-49 T 01-11-2018 MLA2C4_20060 493aa6ad48d69a4ed4189ce09aafa338 296 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 5.6E-120 T 01-11-2018 IPR019991 GTP-binding protein, ribosome biogenesis MLA2C4_20060 493aa6ad48d69a4ed4189ce09aafa338 296 Pfam PF01926 50S ribosome-binding GTPase 123 213 2.9E-17 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_20060 493aa6ad48d69a4ed4189ce09aafa338 296 PIRSF PIRSF006230 1 283 8.2E-107 T 01-11-2018 IPR016478 GTPase, MTG1 MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 Pfam PF00571 CBS domain 288 338 6.5E-7 T 01-11-2018 IPR000644 CBS domain MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 Pfam PF00571 CBS domain 217 270 2.4E-4 T 01-11-2018 IPR000644 CBS domain MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 SUPERFAMILY SSF54631 204 341 2.91E-30 T 01-11-2018 MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 Gene3D G3DSA:3.30.465.10 348 432 6.8E-17 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 Pfam PF03471 Transporter associated domain 356 430 1.0E-15 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 Pfam PF01595 Domain of unknown function DUF21 8 201 1.2E-51 T 01-11-2018 IPR002550 CNNM, transmembrane domain MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 SMART SM01091 354 431 1.7E-20 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 Gene3D G3DSA:3.10.580.10 195 347 3.8E-49 T 01-11-2018 MLA2C4_03210 343fcbe2f33e90bdb1a5c4cd336dc76e 432 SUPERFAMILY SSF56176 352 431 2.73E-15 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_03940 cde675c1396bd3ba3e3e6078c5faab50 206 SUPERFAMILY SSF51391 7 199 5.36E-43 T 01-11-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_03940 cde675c1396bd3ba3e3e6078c5faab50 206 Pfam PF02581 Thiamine monophosphate synthase 8 181 1.8E-40 T 01-11-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_03940 cde675c1396bd3ba3e3e6078c5faab50 206 Gene3D G3DSA:3.20.20.70 3 205 3.3E-49 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 Pfam PF00176 SNF2 family N-terminal domain 263 424 1.9E-13 T 01-11-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 Gene3D G3DSA:3.40.50.300 650 853 9.0E-31 T 01-11-2018 MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 SUPERFAMILY SSF52540 299 850 4.89E-35 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 SUPERFAMILY SSF52540 179 371 1.72E-10 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 Pfam PF00271 Helicase conserved C-terminal domain 702 826 3.2E-13 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 Gene3D G3DSA:3.40.50.10810 249 504 9.7E-26 T 01-11-2018 IPR038718 SNF2-like, N-terminal domain superfamily MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 SMART SM00490 723 826 1.2E-13 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_06760 b2082cd76e6ba167c68f73bb57b47a7e 1084 SMART SM00487 247 437 6.4E-12 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_11130 bda6857a6e953ecb5b357a91b868c00b 146 Pfam PF00583 Acetyltransferase (GNAT) family 40 133 3.1E-15 T 01-11-2018 IPR000182 GNAT domain MLA2C4_11130 bda6857a6e953ecb5b357a91b868c00b 146 SUPERFAMILY SSF55729 1 143 2.48E-30 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_11130 bda6857a6e953ecb5b357a91b868c00b 146 Gene3D G3DSA:3.40.630.30 1 139 2.1E-35 T 01-11-2018 MLA2C4_13185 399a84517b4203128d685c876d4297ae 228 SMART SM00849 19 222 6.8E-21 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_13185 399a84517b4203128d685c876d4297ae 228 Pfam PF00753 Metallo-beta-lactamase superfamily 24 215 5.0E-19 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_13185 399a84517b4203128d685c876d4297ae 228 SUPERFAMILY SSF56281 21 224 1.06E-37 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_13185 399a84517b4203128d685c876d4297ae 228 Gene3D G3DSA:3.60.15.10 10 227 6.3E-35 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_01395 628c2112ce499e5c81b89503b35390e3 320 Pfam PF03851 UV-endonuclease UvdE 5 275 5.3E-89 T 01-11-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 MLA2C4_01395 628c2112ce499e5c81b89503b35390e3 320 SUPERFAMILY SSF51658 80 290 6.22E-13 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily MLA2C4_01395 628c2112ce499e5c81b89503b35390e3 320 Gene3D G3DSA:3.20.20.150 2 310 2.8E-97 T 01-11-2018 MLA2C4_01395 628c2112ce499e5c81b89503b35390e3 320 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 2 304 1.0E-67 T 01-11-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 MLA2C4_11540 4aef031d85bc7e501223e8571339d530 211 Gene3D G3DSA:1.20.144.10 117 210 1.4E-25 T 01-11-2018 MLA2C4_11540 4aef031d85bc7e501223e8571339d530 211 Gene3D G3DSA:1.20.144.10 2 116 2.2E-8 T 01-11-2018 MLA2C4_11540 4aef031d85bc7e501223e8571339d530 211 SMART SM00014 85 198 7.9E-24 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_11540 4aef031d85bc7e501223e8571339d530 211 SUPERFAMILY SSF48317 6 203 1.44E-38 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_11540 4aef031d85bc7e501223e8571339d530 211 Pfam PF01569 PAP2 superfamily 95 203 1.8E-21 T 01-11-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MLA2C4_26055 75bbb4621b600e651c61b0e14b186fd5 305 PIRSF PIRSF000196 1 305 2.3E-135 T 01-11-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 MLA2C4_26055 75bbb4621b600e651c61b0e14b186fd5 305 Pfam PF01619 Proline dehydrogenase 45 298 2.1E-37 T 01-11-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MLA2C4_26055 75bbb4621b600e651c61b0e14b186fd5 305 SUPERFAMILY SSF51730 37 300 9.02E-78 T 01-11-2018 IPR029041 FAD-linked oxidoreductase-like MLA2C4_26055 75bbb4621b600e651c61b0e14b186fd5 305 Gene3D G3DSA:3.20.20.530 19 305 5.3E-99 T 01-11-2018 MLA2C4_21350 3803534cd651303bafad4213bb4de9f0 354 Pfam PF13346 ABC-2 family transporter protein 66 195 8.2E-6 T 01-11-2018 IPR025699 ABC-2 membrane transporter-like MLA2C4_19515 e0c918658a8fdb075a9373e8e0d0609d 335 SUPERFAMILY SSF81345 7 327 3.4E-77 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_19515 e0c918658a8fdb075a9373e8e0d0609d 335 Gene3D G3DSA:1.10.3470.10 5 333 3.9E-85 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_19515 e0c918658a8fdb075a9373e8e0d0609d 335 Pfam PF01032 FecCD transport family 18 327 5.5E-83 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_03425 db93982aa690714d173c1d8b993dbd9e 317 Pfam PF08279 HTH domain 6 61 2.2E-15 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_03425 db93982aa690714d173c1d8b993dbd9e 317 SUPERFAMILY SSF46785 3 60 1.53E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03425 db93982aa690714d173c1d8b993dbd9e 317 Gene3D G3DSA:1.10.10.10 1 63 5.7E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03425 db93982aa690714d173c1d8b993dbd9e 317 Pfam PF13280 WYL domain 139 307 2.8E-26 T 01-11-2018 IPR026881 WYL domain MLA2C4_03425 db93982aa690714d173c1d8b993dbd9e 317 PIRSF PIRSF016838 2 317 1.4E-19 T 01-11-2018 IPR028349 Protein PafC MLA2C4_23070 861d7458de06659e858defa13c203c40 106 Gene3D G3DSA:1.10.10.10 2 105 9.1E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_23070 861d7458de06659e858defa13c203c40 106 SMART SM00418 21 97 1.0E-21 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_23070 861d7458de06659e858defa13c203c40 106 Pfam PF01022 Bacterial regulatory protein, arsR family 28 73 7.8E-15 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_23070 861d7458de06659e858defa13c203c40 106 SUPERFAMILY SSF46785 20 102 1.92E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23070 861d7458de06659e858defa13c203c40 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 8.0E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_23070 861d7458de06659e858defa13c203c40 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 8.0E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_23070 861d7458de06659e858defa13c203c40 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 8.0E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18060 abd67c527006d915a6b6f876044442f7 338 Gene3D G3DSA:1.10.3470.10 9 338 1.6E-93 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_18060 abd67c527006d915a6b6f876044442f7 338 SUPERFAMILY SSF81345 9 336 3.79E-80 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_18060 abd67c527006d915a6b6f876044442f7 338 Pfam PF01032 FecCD transport family 24 336 1.7E-89 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_14820 59613ace5e6f4c68fd3b0c9458db154f 235 Gene3D G3DSA:3.40.50.150 29 235 2.1E-45 T 01-11-2018 MLA2C4_14820 59613ace5e6f4c68fd3b0c9458db154f 235 SUPERFAMILY SSF53335 3 199 4.6E-40 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_14820 59613ace5e6f4c68fd3b0c9458db154f 235 Pfam PF08241 Methyltransferase domain 49 141 1.0E-25 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.3E-17 T 01-11-2018 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.3E-17 T 01-11-2018 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 1.3E-17 T 01-11-2018 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 1.3E-17 T 01-11-2018 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 Gene3D G3DSA:3.50.50.60 7 308 2.5E-84 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 307 3.6E-26 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 SUPERFAMILY SSF51905 1 318 8.29E-37 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 Hamap MF_01685 Ferredoxin--NADP reductase. 6 333 37.264 T 01-11-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 Gene3D G3DSA:3.50.50.60 127 248 2.5E-84 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 9.1E-25 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 9.1E-25 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 9.1E-25 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 9.1E-25 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02075 be33ca25b5aea0fb178a9b54187f3ee9 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 9.1E-25 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_02235 5052b16f1dc9e06769a6bb3680a29ffc 249 Gene3D G3DSA:3.40.50.150 21 245 1.2E-13 T 01-11-2018 MLA2C4_02235 5052b16f1dc9e06769a6bb3680a29ffc 249 SUPERFAMILY SSF53335 28 229 1.47E-17 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_02235 5052b16f1dc9e06769a6bb3680a29ffc 249 Pfam PF08241 Methyltransferase domain 62 156 9.8E-6 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_21540 4252eea7d4e3f554d2b16108ae3ae1c0 269 SUPERFAMILY SSF53335 10 188 1.67E-37 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_21540 4252eea7d4e3f554d2b16108ae3ae1c0 269 Gene3D G3DSA:3.40.50.150 7 237 2.8E-45 T 01-11-2018 MLA2C4_21540 4252eea7d4e3f554d2b16108ae3ae1c0 269 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 2 265 30.116 T 01-11-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 MLA2C4_21540 4252eea7d4e3f554d2b16108ae3ae1c0 269 Pfam PF13847 Methyltransferase domain 43 165 1.1E-23 T 01-11-2018 IPR025714 Methyltransferase domain MLA2C4_21540 4252eea7d4e3f554d2b16108ae3ae1c0 269 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 10 265 2.6E-79 T 01-11-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 MLA2C4_19510 898c795603bb26c08b10925c94538618 340 SUPERFAMILY SSF81345 5 337 8.11E-77 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_19510 898c795603bb26c08b10925c94538618 340 Pfam PF01032 FecCD transport family 19 337 9.9E-87 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_19510 898c795603bb26c08b10925c94538618 340 Gene3D G3DSA:1.10.3470.10 6 340 1.1E-94 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_18835 cc2ba7b56a5de54c1045ea02cd2c7954 412 Pfam PF07690 Major Facilitator Superfamily 15 349 6.1E-33 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_18835 cc2ba7b56a5de54c1045ea02cd2c7954 412 SUPERFAMILY SSF103473 14 392 2.88E-53 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_18835 cc2ba7b56a5de54c1045ea02cd2c7954 412 Gene3D G3DSA:1.20.1250.20 13 390 9.5E-46 T 01-11-2018 MLA2C4_15595 4249b231174db5588453d9f1a344f5a4 172 Pfam PF13671 AAA domain 10 54 3.1E-6 T 01-11-2018 MLA2C4_15595 4249b231174db5588453d9f1a344f5a4 172 SUPERFAMILY SSF52540 9 146 3.25E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15595 4249b231174db5588453d9f1a344f5a4 172 Gene3D G3DSA:3.40.50.300 8 144 7.8E-18 T 01-11-2018 MLA2C4_21610 c7d6bce2da838ea110d1b9388d48cc49 255 Gene3D G3DSA:3.40.1160.10 2 253 1.9E-71 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_21610 c7d6bce2da838ea110d1b9388d48cc49 255 PIRSF PIRSF000728 1 251 2.8E-86 T 01-11-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21610 c7d6bce2da838ea110d1b9388d48cc49 255 SUPERFAMILY SSF53633 2 250 1.96E-64 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_21610 c7d6bce2da838ea110d1b9388d48cc49 255 Hamap MF_00082 Acetylglutamate kinase [argB]. 2 247 42.273 T 01-11-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21610 c7d6bce2da838ea110d1b9388d48cc49 255 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 229 8.3E-72 T 01-11-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_21610 c7d6bce2da838ea110d1b9388d48cc49 255 Pfam PF00696 Amino acid kinase family 5 231 4.9E-44 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MLA2C4_20775 0e02e155b83987179011807181b025fa 257 Gene3D G3DSA:3.30.1240.10 81 180 2.5E-85 T 01-11-2018 MLA2C4_20775 0e02e155b83987179011807181b025fa 257 SUPERFAMILY SSF56784 1 252 8.66E-69 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_20775 0e02e155b83987179011807181b025fa 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 3.6E-64 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_20775 0e02e155b83987179011807181b025fa 257 Gene3D G3DSA:3.40.50.1000 4 248 2.5E-85 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_20775 0e02e155b83987179011807181b025fa 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 01-11-2018 MLA2C4_20775 0e02e155b83987179011807181b025fa 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 4.9E-62 T 01-11-2018 MLA2C4_20775 0e02e155b83987179011807181b025fa 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 8.6E-23 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 2.2E-129 T 01-11-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 Pfam PF13646 HEAT repeats 300 365 5.6E-10 T 01-11-2018 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 SUPERFAMILY SSF54862 164 252 1.0E-16 T 01-11-2018 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 Gene3D G3DSA:1.25.10.10 264 379 1.5E-10 T 01-11-2018 IPR011989 Armadillo-like helical MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 Pfam PF13484 4Fe-4S double cluster binding domain 187 250 7.8E-16 T 01-11-2018 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 5.0E-18 T 01-11-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 SMART SM00567 E-Z type HEAT repeats 330 359 4.9E-4 T 01-11-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 SMART SM00567 E-Z type HEAT repeats 298 327 89.0 T 01-11-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.721 T 01-11-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MLA2C4_02930 fd02743caa839654a1551f046fce531f 380 SUPERFAMILY SSF48371 295 373 3.17E-10 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_18450 318d7828c6cfa0ad5dd96621c0a1fc14 494 Pfam PF00171 Aldehyde dehydrogenase family 29 489 4.2E-192 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_18450 318d7828c6cfa0ad5dd96621c0a1fc14 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 01-11-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MLA2C4_18450 318d7828c6cfa0ad5dd96621c0a1fc14 494 Gene3D G3DSA:3.40.309.10 270 459 2.1E-202 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_18450 318d7828c6cfa0ad5dd96621c0a1fc14 494 Gene3D G3DSA:3.40.605.10 24 487 2.1E-202 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_18450 318d7828c6cfa0ad5dd96621c0a1fc14 494 SUPERFAMILY SSF53720 15 492 7.59E-183 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 Gene3D G3DSA:3.40.50.1820 3 279 8.3E-60 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 Pfam PF00561 alpha/beta hydrolase fold 33 265 7.2E-23 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 4.9E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 4.9E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 4.9E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 4.9E-13 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 SUPERFAMILY SSF53474 6 276 3.69E-59 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00412 Epoxide hydrolase signature 254 276 1.1E-8 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00412 Epoxide hydrolase signature 221 237 1.1E-8 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00412 Epoxide hydrolase signature 39 57 1.1E-8 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_25530 7a9483548d1018ac37760efe9df3fa15 279 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.1E-8 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_15905 c66852ebfc1039f08e047516ac45eb20 388 Pfam PF00144 Beta-lactamase 60 371 1.7E-67 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_15905 c66852ebfc1039f08e047516ac45eb20 388 SUPERFAMILY SSF56601 53 379 1.61E-82 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_15905 c66852ebfc1039f08e047516ac45eb20 388 Gene3D G3DSA:3.40.710.10 45 388 1.5E-130 T 01-11-2018 MLA2C4_05090 4b525a417b2bb3d5ba5e174d2c56db63 88 Pfam PF14157 YmzC-like protein 28 87 1.6E-25 T 01-11-2018 IPR025448 YmzC-like protein MLA2C4_20840 65ab744d147fd8221287043e742e1a82 78 Gene3D G3DSA:3.40.30.10 1 78 2.5E-25 T 01-11-2018 MLA2C4_20840 65ab744d147fd8221287043e742e1a82 78 SUPERFAMILY SSF52833 2 76 5.14E-17 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_20840 65ab744d147fd8221287043e742e1a82 78 TIGRFAM TIGR02196 GlrX_YruB: glutaredoxin-like protein, YruB-family 3 76 2.1E-30 T 01-11-2018 IPR011911 Glutaredoxin-like protein, YruB MLA2C4_20840 65ab744d147fd8221287043e742e1a82 78 Pfam PF00462 Glutaredoxin 4 63 5.8E-14 T 01-11-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MLA2C4_06240 63b3b402860476489eed4483640c8785 481 PIRSF PIRSF006603 13 474 9.0E-86 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_06240 63b3b402860476489eed4483640c8785 481 Pfam PF01554 MatE 39 199 6.3E-25 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_06240 63b3b402860476489eed4483640c8785 481 Pfam PF01554 MatE 264 424 7.0E-29 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_06240 63b3b402860476489eed4483640c8785 481 TIGRFAM TIGR00797 matE: MATE efflux family protein 39 438 1.9E-65 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 SUPERFAMILY SSF53850 233 501 9.34E-75 T 01-11-2018 MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 Gene3D G3DSA:3.40.190.10 244 502 3.8E-98 T 01-11-2018 MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 201 4.8E-28 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 Gene3D G3DSA:3.40.190.120 337 440 3.8E-98 T 01-11-2018 MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 233 498 2.3E-69 T 01-11-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 SUPERFAMILY SSF161098 15 198 8.11E-42 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_11405 67da37e54ef1bbc6139905969013b831 503 Gene3D G3DSA:1.10.3720.10 12 203 3.8E-37 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_18505 5915589dcce71cca8e40c321034848e8 154 Gene3D G3DSA:3.90.1170.40 3 149 1.9E-54 T 01-11-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MLA2C4_18505 5915589dcce71cca8e40c321034848e8 154 SUPERFAMILY SSF54690 6 139 1.83E-46 T 01-11-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MLA2C4_18505 5915589dcce71cca8e40c321034848e8 154 Pfam PF02391 MoaE protein 12 119 6.9E-38 T 01-11-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 Pfam PF01470 Pyroglutamyl peptidase 3 201 2.9E-84 T 01-11-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 PIRSF PIRSF015592 1 213 3.6E-90 T 01-11-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 2.5E-48 T 01-11-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 2.5E-48 T 01-11-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 2.5E-48 T 01-11-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 2.5E-48 T 01-11-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 2.5E-48 T 01-11-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 01-11-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 SUPERFAMILY SSF53182 1 214 7.19E-75 T 01-11-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 213 7.5E-87 T 01-11-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 41.742 T 01-11-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 Gene3D G3DSA:3.40.630.20 1 215 1.1E-90 T 01-11-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 MLA2C4_16160 5831e012243684d628196afb1401cc50 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 01-11-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 MLA2C4_25175 8349b27262d078a90cbea1cde31728e6 657 PIRSF PIRSF018968 1 653 5.7E-123 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_25175 8349b27262d078a90cbea1cde31728e6 657 Pfam PF02687 FtsX-like permease family 84 169 7.5E-8 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_05440 06ba8c7d85b48b3e9a9895f4e983e7b8 66 Gene3D G3DSA:1.10.260.40 3 66 2.1E-24 T 01-11-2018 MLA2C4_05440 06ba8c7d85b48b3e9a9895f4e983e7b8 66 SUPERFAMILY SSF47413 6 65 5.36E-18 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_05440 06ba8c7d85b48b3e9a9895f4e983e7b8 66 SMART SM00530 6 61 1.9E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_05440 06ba8c7d85b48b3e9a9895f4e983e7b8 66 Pfam PF01381 Helix-turn-helix 7 60 1.1E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_22375 389299d424c8d450f9bf2985d29cb8cd 277 SUPERFAMILY SSF81345 3 267 1.02E-37 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_22375 389299d424c8d450f9bf2985d29cb8cd 277 Gene3D G3DSA:1.10.3470.10 44 276 5.0E-10 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_22375 389299d424c8d450f9bf2985d29cb8cd 277 Pfam PF00950 ABC 3 transport family 7 270 4.3E-64 T 01-11-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MLA2C4_21035 b4fd85c7590f3fc5b0c34ccb7397a01d 250 SUPERFAMILY SSF52540 34 222 1.7E-23 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21035 b4fd85c7590f3fc5b0c34ccb7397a01d 250 SMART SM00382 39 217 1.3E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_21035 b4fd85c7590f3fc5b0c34ccb7397a01d 250 Gene3D G3DSA:3.40.50.300 27 114 3.3E-11 T 01-11-2018 MLA2C4_21035 b4fd85c7590f3fc5b0c34ccb7397a01d 250 Gene3D G3DSA:3.40.50.300 131 225 3.4E-9 T 01-11-2018 MLA2C4_21035 b4fd85c7590f3fc5b0c34ccb7397a01d 250 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 160 205 3.4E-7 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_21035 b4fd85c7590f3fc5b0c34ccb7397a01d 250 Pfam PF13476 AAA domain 34 84 4.6E-11 T 01-11-2018 IPR038729 Rad50/SbcC-type AAA domain MLA2C4_04660 9917262ade554ecf3f919829ce4b3fba 265 Gene3D G3DSA:3.40.190.10 126 223 4.2E-72 T 01-11-2018 MLA2C4_04660 9917262ade554ecf3f919829ce4b3fba 265 SMART SM00079 43 261 0.0019 T 01-11-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MLA2C4_04660 9917262ade554ecf3f919829ce4b3fba 265 SMART SM00062 43 262 2.6E-72 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_04660 9917262ade554ecf3f919829ce4b3fba 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 1.6E-62 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_04660 9917262ade554ecf3f919829ce4b3fba 265 Gene3D G3DSA:3.40.190.10 42 254 4.2E-72 T 01-11-2018 MLA2C4_04660 9917262ade554ecf3f919829ce4b3fba 265 SUPERFAMILY SSF53850 1 262 4.24E-68 T 01-11-2018 MLA2C4_06935 0a29eedb1c7aa13ed048905d0ff2a97c 236 Pfam PF02589 LUD domain 51 236 1.3E-35 T 01-11-2018 IPR003741 LUD domain MLA2C4_06935 0a29eedb1c7aa13ed048905d0ff2a97c 236 SUPERFAMILY SSF100950 45 236 2.97E-39 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_06935 0a29eedb1c7aa13ed048905d0ff2a97c 236 Gene3D G3DSA:3.40.50.10420 44 236 1.1E-37 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MLA2C4_06935 0a29eedb1c7aa13ed048905d0ff2a97c 236 Hamap MF_02104 Lactate utilization protein C [lutC]. 4 236 49.588 T 01-11-2018 IPR022823 Lactate utilization protein C MLA2C4_10135 a8ee4791367aaa65fdfeaeb841db8c7c 321 SUPERFAMILY SSF52151 6 301 7.59E-45 T 01-11-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MLA2C4_10135 a8ee4791367aaa65fdfeaeb841db8c7c 321 Pfam PF01734 Patatin-like phospholipase 6 198 4.4E-31 T 01-11-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MLA2C4_10135 a8ee4791367aaa65fdfeaeb841db8c7c 321 Gene3D G3DSA:3.40.1090.10 2 115 4.8E-25 T 01-11-2018 MLA2C4_12370 41039fc822a0ae3ffddd642c00972ef7 274 Pfam PF04072 Leucine carboxyl methyltransferase 20 174 1.4E-10 T 01-11-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 MLA2C4_12370 41039fc822a0ae3ffddd642c00972ef7 274 PIRSF PIRSF028177 1 273 3.1E-67 T 01-11-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 MLA2C4_12370 41039fc822a0ae3ffddd642c00972ef7 274 SUPERFAMILY SSF53335 13 260 1.66E-37 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_12370 41039fc822a0ae3ffddd642c00972ef7 274 Gene3D G3DSA:3.40.50.150 6 227 5.0E-26 T 01-11-2018 MLA2C4_13890 e232dfa4327e6d9c49460e01bf8699f9 229 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 214 9.8E-76 T 01-11-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 MLA2C4_13890 e232dfa4327e6d9c49460e01bf8699f9 229 Pfam PF03070 TENA/THI-4/PQQC family 9 214 6.3E-58 T 01-11-2018 IPR004305 Thiaminase-2/PQQC MLA2C4_13890 e232dfa4327e6d9c49460e01bf8699f9 229 Gene3D G3DSA:1.20.910.10 1 220 1.0E-66 T 01-11-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MLA2C4_13890 e232dfa4327e6d9c49460e01bf8699f9 229 SUPERFAMILY SSF48613 3 220 8.75E-74 T 01-11-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MLA2C4_14315 3cc3f6b36f7909e09a0a64f69aaefa20 135 Pfam PF09350 Domain of unknown function (DUF1992) 34 95 1.3E-17 T 01-11-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain MLA2C4_04395 a62ddd7cc1acdff4301272bea1bce0db 244 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 226 1.6E-55 T 01-11-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 MLA2C4_04395 a62ddd7cc1acdff4301272bea1bce0db 244 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 11 233 1.7E-84 T 01-11-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 MLA2C4_18090 99f1dd2e01fda625a75dcbc9b1595d04 178 Gene3D G3DSA:3.40.630.30 2 178 1.4E-40 T 01-11-2018 MLA2C4_18090 99f1dd2e01fda625a75dcbc9b1595d04 178 SUPERFAMILY SSF55729 1 169 9.43E-37 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_18090 99f1dd2e01fda625a75dcbc9b1595d04 178 Pfam PF13302 Acetyltransferase (GNAT) domain 7 144 4.7E-19 T 01-11-2018 IPR000182 GNAT domain MLA2C4_24230 8c17d4213cc93657e33d6d4cf63417e5 210 Gene3D G3DSA:3.40.630.30 2 210 1.7E-85 T 01-11-2018 MLA2C4_24230 8c17d4213cc93657e33d6d4cf63417e5 210 PIRSF PIRSF021278 2 210 4.7E-86 T 01-11-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 MLA2C4_24230 8c17d4213cc93657e33d6d4cf63417e5 210 Pfam PF00583 Acetyltransferase (GNAT) family 48 118 8.0E-5 T 01-11-2018 IPR000182 GNAT domain MLA2C4_24230 8c17d4213cc93657e33d6d4cf63417e5 210 SUPERFAMILY SSF55729 41 119 1.5E-7 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 Pfam PF08281 Sigma-70, region 4 108 154 4.2E-15 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 Gene3D G3DSA:1.10.10.10 101 159 1.1E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 Gene3D G3DSA:1.10.1740.10 1 78 1.9E-21 T 01-11-2018 MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 SUPERFAMILY SSF88946 4 92 6.28E-22 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 Pfam PF04542 Sigma-70 region 2 10 76 2.7E-16 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 155 1.3E-24 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 6 160 4.7E-69 T 01-11-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_05860 b6c0e640de7294ab71e4e5fe805f264d 161 SUPERFAMILY SSF88659 104 154 9.16E-12 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_03660 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 SUPERFAMILY SSF47413 5 64 2.36E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_03660 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 Pfam PF01381 Helix-turn-helix 6 56 6.7E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_03660 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 Gene3D G3DSA:1.10.260.40 1 65 9.3E-26 T 01-11-2018 MLA2C4_03660 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 SMART SM00530 5 60 3.5E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_04090 5d71fa296ea7c6c0209e7d537da41ee8 169 Pfam PF13798 Protein of unknown function with PCYCGC motif 9 167 1.1E-72 T 01-11-2018 IPR025673 Protein of unknown function with PCYCGC motif MLA2C4_06340 6400107edfe22d1aeabb63640a358f09 252 Gene3D G3DSA:3.40.50.150 23 228 4.4E-30 T 01-11-2018 MLA2C4_06340 6400107edfe22d1aeabb63640a358f09 252 SUPERFAMILY SSF53335 26 224 7.63E-30 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_06340 6400107edfe22d1aeabb63640a358f09 252 Pfam PF08241 Methyltransferase domain 48 163 2.4E-22 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 SUPERFAMILY SSF103473 1 395 6.8E-45 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 Pfam PF07690 Major Facilitator Superfamily 16 354 2.0E-25 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 Gene3D G3DSA:1.20.1250.20 8 394 1.2E-34 T 01-11-2018 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 PRINTS PR01988 Putative bacilysin exporter bacE signature 76 94 2.4E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 PRINTS PR01988 Putative bacilysin exporter bacE signature 164 181 2.4E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 PRINTS PR01988 Putative bacilysin exporter bacE signature 13 35 2.4E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 PRINTS PR01988 Putative bacilysin exporter bacE signature 299 322 2.4E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 PRINTS PR01988 Putative bacilysin exporter bacE signature 362 385 2.4E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_14145 dba00e84a6acf974b39bd7badfa6c9c8 412 PRINTS PR01988 Putative bacilysin exporter bacE signature 137 158 2.4E-7 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_26245 af40f731b2a51121fbbd07535b5dbad7 105 Gene3D G3DSA:3.30.300.130 1 105 1.1E-37 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_26245 af40f731b2a51121fbbd07535b5dbad7 105 Pfam PF01883 Iron-sulfur cluster assembly protein 8 82 1.3E-17 T 01-11-2018 IPR002744 MIP18 family-like MLA2C4_26245 af40f731b2a51121fbbd07535b5dbad7 105 SUPERFAMILY SSF117916 5 102 9.48E-30 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 Pfam PF00155 Aminotransferase class I and II 118 460 2.5E-36 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 SUPERFAMILY SSF53383 108 475 3.4E-95 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.6E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.6E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 Gene3D G3DSA:1.10.10.10 5 77 8.8E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 SUPERFAMILY SSF46785 6 77 4.17E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 Gene3D G3DSA:3.40.640.10 151 371 6.5E-107 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 SMART SM00345 17 76 7.0E-18 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 Gene3D G3DSA:3.90.1150.10 114 473 6.5E-107 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_19630 1b54f28eb49c9d0a52b7d20895ddc98d 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 8.2E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_19720 4a4d631e8143015181bef47df0682b56 143 SUPERFAMILY SSF158622 4 123 1.57E-36 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily MLA2C4_19720 4a4d631e8143015181bef47df0682b56 143 Gene3D G3DSA:1.20.1500.10 1 124 1.5E-36 T 01-11-2018 IPR023378 YheA/YmcA-like domain superfamily MLA2C4_19720 4a4d631e8143015181bef47df0682b56 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 2.4E-25 T 01-11-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA MLA2C4_19720 4a4d631e8143015181bef47df0682b56 143 PIRSF PIRSF021287 1 123 1.1E-52 T 01-11-2018 IPR016783 Biofilm formation YmcA MLA2C4_06400 8d75b054462bcf6656c2ee3dc569897a 179 Pfam PF14153 Spore coat protein CotO 13 179 1.4E-50 T 01-11-2018 IPR025439 Spore coat protein CotO MLA2C4_04010 6118a960da98387866874e645ec1142d 393 Pfam PF07690 Major Facilitator Superfamily 14 232 2.2E-35 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_04010 6118a960da98387866874e645ec1142d 393 SUPERFAMILY SSF103473 5 385 3.92E-75 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_04010 6118a960da98387866874e645ec1142d 393 Gene3D G3DSA:1.20.1720.10 9 348 1.7E-78 T 01-11-2018 MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 Pfam PF00563 EAL domain 657 891 5.8E-67 T 01-11-2018 IPR001633 EAL domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 355 474 5.0E-18 T 01-11-2018 IPR000014 PAS domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 Gene3D G3DSA:3.30.450.20 353 476 6.2E-22 T 01-11-2018 MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SMART SM00052 650 896 9.2E-109 T 01-11-2018 IPR001633 EAL domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 476 637 5.2E-38 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 Pfam PF00990 Diguanylate cyclase, GGDEF domain 479 635 2.7E-47 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SUPERFAMILY SSF141868 655 908 6.41E-84 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 Gene3D G3DSA:3.30.70.270 477 653 2.5E-59 T 01-11-2018 MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SMART SM00091 356 422 2.5E-7 T 01-11-2018 IPR000014 PAS domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 Gene3D G3DSA:3.20.20.450 654 905 2.1E-92 T 01-11-2018 IPR035919 EAL domain superfamily MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 Pfam PF13426 PAS domain 366 467 1.8E-11 T 01-11-2018 IPR000014 PAS domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SUPERFAMILY SSF55073 484 641 4.47E-47 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SMART SM00267 468 640 1.3E-60 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SUPERFAMILY SSF55785 344 466 4.19E-22 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_27440 c1df0f51dcf496a87b37f31334f623b9 922 SMART SM00086 427 468 0.0011 T 01-11-2018 IPR001610 PAC motif MLA2C4_26795 0219686f092bd7fa0531a0f495f96026 103 SUPERFAMILY SSF117782 1 103 7.19E-36 T 01-11-2018 IPR035439 UPF0145 domain superfamily MLA2C4_26795 0219686f092bd7fa0531a0f495f96026 103 Pfam PF01906 Putative heavy-metal-binding 1 103 6.5E-37 T 01-11-2018 IPR002765 Uncharacterised protein family UPF0145 MLA2C4_26795 0219686f092bd7fa0531a0f495f96026 103 Gene3D G3DSA:3.30.110.70 1 103 8.8E-43 T 01-11-2018 MLA2C4_26795 0219686f092bd7fa0531a0f495f96026 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.046 T 01-11-2018 IPR002765 Uncharacterised protein family UPF0145 MLA2C4_08820 cd10327ea0013b5646ae48821923c08a 404 Gene3D G3DSA:1.25.40.10 311 403 2.6E-7 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_08820 cd10327ea0013b5646ae48821923c08a 404 SUPERFAMILY SSF47413 2 67 2.2E-15 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_08820 cd10327ea0013b5646ae48821923c08a 404 SMART SM00530 7 61 3.6E-13 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_08820 cd10327ea0013b5646ae48821923c08a 404 Gene3D G3DSA:1.25.40.10 1 274 5.0E-26 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_08820 cd10327ea0013b5646ae48821923c08a 404 Pfam PF12844 Helix-turn-helix domain 5 66 3.8E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_08820 cd10327ea0013b5646ae48821923c08a 404 SUPERFAMILY SSF48452 190 396 2.85E-10 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 SUPERFAMILY SSF53335 16 286 6.23E-77 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 19 287 56.91 T 01-11-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 Gene3D G3DSA:1.10.8.100 219 288 1.7E-23 T 01-11-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 01-11-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 Gene3D G3DSA:3.40.50.150 1 215 1.0E-74 T 01-11-2018 MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 19 280 2.1E-76 T 01-11-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 SMART SM00650 35 211 9.9E-86 T 01-11-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MLA2C4_00240 a4e906d17273f3b2cd01707f5dc38429 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 19 286 1.3E-88 T 01-11-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MLA2C4_18515 324f72dd30bb5883152c383a164465b0 338 Gene3D G3DSA:3.40.50.720 1 250 3.3E-75 T 01-11-2018 MLA2C4_18515 324f72dd30bb5883152c383a164465b0 338 Pfam PF00899 ThiF family 5 241 1.3E-62 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MLA2C4_18515 324f72dd30bb5883152c383a164465b0 338 SUPERFAMILY SSF69572 3 328 8.11E-90 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_07810 2b8f6a1aaf63bb85a56f600ddd2ff4f2 82 Gene3D G3DSA:3.30.70.20 2 82 1.8E-34 T 01-11-2018 MLA2C4_07810 2b8f6a1aaf63bb85a56f600ddd2ff4f2 82 SUPERFAMILY SSF54862 4 72 1.61E-13 T 01-11-2018 MLA2C4_07810 2b8f6a1aaf63bb85a56f600ddd2ff4f2 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 3.8E-21 T 01-11-2018 MLA2C4_07810 2b8f6a1aaf63bb85a56f600ddd2ff4f2 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.9E-8 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MLA2C4_07810 2b8f6a1aaf63bb85a56f600ddd2ff4f2 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 2.9E-8 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MLA2C4_07810 2b8f6a1aaf63bb85a56f600ddd2ff4f2 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.9E-8 T 01-11-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 MLA2C4_06365 f768ee19eb0314b1cec7760350443bc9 228 Pfam PF13712 Glycosyltransferase like family 10 220 5.3E-81 T 01-11-2018 MLA2C4_06365 f768ee19eb0314b1cec7760350443bc9 228 Gene3D G3DSA:3.90.550.10 8 227 3.7E-44 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Gene3D G3DSA:3.40.120.10 327 454 2.2E-37 T 01-11-2018 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 SUPERFAMILY SSF53738 209 317 1.14E-19 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 SUPERFAMILY SSF53738 29 238 9.81E-48 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 1.6E-22 T 01-11-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Gene3D G3DSA:3.40.120.10 209 326 6.7E-22 T 01-11-2018 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 SUPERFAMILY SSF55957 470 556 3.66E-15 T 01-11-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 SUPERFAMILY SSF53738 306 457 4.71E-32 T 01-11-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 01-11-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Gene3D G3DSA:3.40.120.10 33 190 5.0E-47 T 01-11-2018 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Gene3D G3DSA:3.30.310.50 464 570 2.4E-9 T 01-11-2018 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 179 3.3E-41 T 01-11-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 1.1E-5 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 1.1E-5 T 01-11-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 1.3E-22 T 01-11-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_25605 f96e7010134457bf8fc24d21d011ce54 574 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 495 555 8.9E-11 T 01-11-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MLA2C4_09870 68a77c3e2fdbf3ab4648b2e3061eb71a 338 PIRSF PIRSF000267 1 338 7.0E-112 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_09870 68a77c3e2fdbf3ab4648b2e3061eb71a 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 226 5.5E-85 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_09870 68a77c3e2fdbf3ab4648b2e3061eb71a 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 2.6E-104 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 Gene3D G3DSA:1.10.357.10 65 192 3.6E-9 T 01-11-2018 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 1.3E-16 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 SUPERFAMILY SSF46689 5 64 2.87E-16 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.5E-11 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-11 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 Gene3D G3DSA:1.10.10.60 6 64 8.8E-17 T 01-11-2018 MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_05650 df4e9f6f407b4a44ace4300e08b20352 193 SUPERFAMILY SSF48498 94 164 6.49E-5 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_09160 079aedfb07c876b7eb52845a633d22d7 310 SMART SM00448 4 114 1.3E-14 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09160 079aedfb07c876b7eb52845a633d22d7 310 Pfam PF00072 Response regulator receiver domain 5 114 9.6E-19 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09160 079aedfb07c876b7eb52845a633d22d7 310 SUPERFAMILY SSF52172 5 138 8.54E-22 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_09160 079aedfb07c876b7eb52845a633d22d7 310 Pfam PF08664 YcbB domain 160 299 1.1E-49 T 01-11-2018 IPR013972 YcbB domain MLA2C4_09160 079aedfb07c876b7eb52845a633d22d7 310 Gene3D G3DSA:3.40.50.12740 4 158 3.0E-21 T 01-11-2018 MLA2C4_25105 b22166c3781e83688c5c23cfa5ec9121 107 Pfam PF06486 Protein of unknown function (DUF1093) 34 101 6.9E-13 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_25105 b22166c3781e83688c5c23cfa5ec9121 107 Gene3D G3DSA:2.40.50.480 27 107 6.9E-15 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_25105 b22166c3781e83688c5c23cfa5ec9121 107 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 106 2.4E-11 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_25105 b22166c3781e83688c5c23cfa5ec9121 107 SUPERFAMILY SSF159121 27 107 1.27E-18 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Gene3D G3DSA:3.30.450.40 180 325 1.2E-6 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 566 666 5.9E-15 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Gene3D G3DSA:3.30.565.10 521 672 6.5E-33 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Pfam PF00512 His Kinase A (phospho-acceptor) domain 459 516 2.8E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 341 449 1.5E-5 T 01-11-2018 IPR000014 PAS domain MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SUPERFAMILY SSF55874 520 665 7.73E-29 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Pfam PF13185 GAF domain 23 164 4.1E-9 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Gene3D G3DSA:3.30.450.40 3 175 8.6E-23 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SMART SM00065 24 173 3.9E-11 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Pfam PF08448 PAS fold 344 441 1.0E-5 T 01-11-2018 IPR013656 PAS fold-4 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SUPERFAMILY SSF47384 454 517 2.94E-13 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SUPERFAMILY SSF55785 348 451 2.44E-10 T 01-11-2018 IPR035965 PAS domain superfamily MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Gene3D G3DSA:1.10.287.130 460 517 1.2E-16 T 01-11-2018 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SMART SM00387 563 669 1.7E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 1.8E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 648 1.8E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 629 1.8E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SMART SM00388 457 522 1.4E-12 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 SUPERFAMILY SSF55781 6 189 2.4E-20 T 01-11-2018 MLA2C4_01980 c9413bbcb31567693c661fafa2101234 672 Gene3D G3DSA:3.30.450.20 332 441 2.3E-19 T 01-11-2018 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 SUPERFAMILY SSF51735 6 158 5.94E-47 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 Gene3D G3DSA:3.40.50.720 8 339 2.5E-135 T 01-11-2018 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 328 7.1E-54 T 01-11-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 SMART SM00859 7 123 2.6E-39 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 SUPERFAMILY SSF55347 131 329 2.59E-71 T 01-11-2018 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 343 1.1E-143 T 01-11-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 Gene3D G3DSA:3.30.360.10 130 325 2.5E-135 T 01-11-2018 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 342 36.529 T 01-11-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 01-11-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 122 6.7E-33 T 01-11-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MLA2C4_12490 6c0cc5d63b620e81f8e38f485b7ee307 347 PIRSF PIRSF000148 5 347 2.3E-122 T 01-11-2018 MLA2C4_09690 af91d653b0a2654b6815c0d6b54844ab 321 Pfam PF01758 Sodium Bile acid symporter family 38 223 1.5E-30 T 01-11-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MLA2C4_09690 af91d653b0a2654b6815c0d6b54844ab 321 Gene3D G3DSA:1.20.1530.20 1 311 1.7E-43 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_02150 f79fd988ee1abfab98f347c14dadd0b9 361 Pfam PF00487 Fatty acid desaturase 54 299 1.2E-37 T 01-11-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Gene3D G3DSA:3.40.50.300 19 307 3.5E-67 T 01-11-2018 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 SUPERFAMILY SSF52540 22 266 3.01E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Gene3D G3DSA:1.10.287.380 576 662 8.4E-6 T 01-11-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Pfam PF16326 ABC transporter C-terminal domain 595 660 9.0E-14 T 01-11-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 SUPERFAMILY SSF52540 334 556 9.34E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 SMART SM00382 373 538 4.5E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 SMART SM00382 46 258 2.9E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Pfam PF12848 ABC transporter 252 338 1.7E-24 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Gene3D G3DSA:3.40.50.300 311 575 6.7E-60 T 01-11-2018 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 ProSitePatterns PS00211 ABC transporters family signature. 185 199 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Pfam PF00005 ABC transporter 37 213 3.9E-27 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01550 63c1998bf896931de6819457efe68b13 662 Pfam PF00005 ABC transporter 365 494 7.5E-22 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_06455 261b516d660da6b4ac803c1fefb0baac 191 Gene3D G3DSA:2.60.120.10 1 142 3.0E-34 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_06455 261b516d660da6b4ac803c1fefb0baac 191 Pfam PF00027 Cyclic nucleotide-binding domain 30 105 1.6E-10 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_06455 261b516d660da6b4ac803c1fefb0baac 191 SMART SM00100 11 130 1.6E-4 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_06455 261b516d660da6b4ac803c1fefb0baac 191 SUPERFAMILY SSF51206 15 139 1.19E-21 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like MLA2C4_04135 d377c6f977096b5d872777320c3ded30 301 Gene3D G3DSA:3.30.460.10 24 150 3.8E-8 T 01-11-2018 MLA2C4_04135 d377c6f977096b5d872777320c3ded30 301 Pfam PF01909 Nucleotidyltransferase domain 60 95 2.9E-6 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MLA2C4_04135 d377c6f977096b5d872777320c3ded30 301 SUPERFAMILY SSF81301 28 166 4.53E-19 T 01-11-2018 MLA2C4_27495 fd91fe82b749c9e0e0ec8011a675d45b 130 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 130 1.0E-47 T 01-11-2018 MLA2C4_27495 fd91fe82b749c9e0e0ec8011a675d45b 130 Pfam PF03899 ATP synthase I chain 11 109 5.6E-15 T 01-11-2018 IPR005598 ATP synthase protein I MLA2C4_18600 50ab5c020327d5a9fa4a8bc3164d7ba9 570 Gene3D G3DSA:3.90.76.10 87 209 6.8E-182 T 01-11-2018 MLA2C4_18600 50ab5c020327d5a9fa4a8bc3164d7ba9 570 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 484 4.4E-76 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_18600 50ab5c020327d5a9fa4a8bc3164d7ba9 570 Gene3D G3DSA:3.40.190.10 68 552 6.8E-182 T 01-11-2018 MLA2C4_18600 50ab5c020327d5a9fa4a8bc3164d7ba9 570 PIRSF PIRSF002741 2 568 9.8E-106 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_18600 50ab5c020327d5a9fa4a8bc3164d7ba9 570 Gene3D G3DSA:3.10.105.10 310 537 6.8E-182 T 01-11-2018 MLA2C4_18600 50ab5c020327d5a9fa4a8bc3164d7ba9 570 SUPERFAMILY SSF53850 52 562 6.52E-124 T 01-11-2018 MLA2C4_06330 db9da3cbc70bd4bf8620fcbe67f55697 386 Pfam PF01098 Cell cycle protein 15 380 3.8E-87 T 01-11-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_06330 db9da3cbc70bd4bf8620fcbe67f55697 386 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 338 362 - T 01-11-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 SMART SM00460 372 428 2.4E-7 T 01-11-2018 IPR002931 Transglutaminase-like MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 SUPERFAMILY SSF54001 321 484 3.43E-26 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 Pfam PF01841 Transglutaminase-like superfamily 331 425 9.0E-14 T 01-11-2018 IPR002931 Transglutaminase-like MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 Gene3D G3DSA:3.10.620.30 305 443 3.8E-21 T 01-11-2018 MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 Pfam PF00395 S-layer homology domain 171 214 3.7E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 Pfam PF00395 S-layer homology domain 111 155 3.3E-8 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05255 fdabd5a5d853982e88acde17083c6f53 578 Pfam PF00395 S-layer homology domain 35 77 1.6E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17320 5c6b031c23c76fd294d0734646de4e5e 240 Pfam PF14256 YwiC-like protein 5 130 7.8E-43 T 01-11-2018 IPR025576 YwiC-like protein MLA2C4_17320 5c6b031c23c76fd294d0734646de4e5e 240 SUPERFAMILY SSF109905 133 177 4.19E-5 T 01-11-2018 IPR035967 SWAP/Surp superfamily GO:0003723|GO:0006396 MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 Pfam PF00072 Response regulator receiver domain 6 115 7.8E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 SUPERFAMILY SSF46894 135 232 8.5E-27 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 Gene3D G3DSA:1.10.10.10 133 234 1.2E-33 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 SMART SM00862 154 231 7.9E-26 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 Gene3D G3DSA:3.40.50.2300 2 132 3.6E-34 T 01-11-2018 MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 SUPERFAMILY SSF52172 4 125 3.13E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 6.3E-25 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_05880 cdda396597ba31eec7b892824f879f3f 234 SMART SM00448 4 115 1.3E-39 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 ProSitePatterns PS00384 Prokaryotic zinc-dependent phospholipase C signature. 156 169 - T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 130 152 7.9E-28 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 153 177 7.9E-28 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 180 197 7.9E-28 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 107 120 7.9E-28 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 266 276 7.9E-28 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 Gene3D G3DSA:1.10.575.10 39 283 9.0E-108 T 01-11-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 SUPERFAMILY SSF48537 39 281 2.75E-63 T 01-11-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 Pfam PF00882 Zinc dependent phospholipase C 51 230 4.3E-20 T 01-11-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 ProDom PD003946 PHOSPHOLIPASE C PLCB HYDROLASE PRECURSOR PHOSPHATIDYLCHOLINE SIGNAL CHOLINEPHOSPHOHYDROLASE TOXIN PLC 47 275 6.0E-134 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_03565 eeaf52bab2af518e1d70714cfdc98887 283 SMART SM00770 1 283 1.3E-130 T 01-11-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 Gene3D G3DSA:3.30.930.10 1 324 1.2E-114 T 01-11-2018 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 Pfam PF13393 Histidyl-tRNA synthetase 8 313 1.4E-44 T 01-11-2018 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 PIRSF PIRSF001549 1 422 4.2E-122 T 01-11-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 Gene3D G3DSA:3.40.50.800 327 423 1.3E-26 T 01-11-2018 IPR036621 Anticodon-binding domain superfamily MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 3.2E-155 T 01-11-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 33.723 T 01-11-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 SUPERFAMILY SSF52954 329 421 3.62E-26 T 01-11-2018 MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 Pfam PF03129 Anticodon binding domain 331 420 5.1E-18 T 01-11-2018 IPR004154 Anticodon-binding MLA2C4_22970 3b7a300754e84b22ed9b7fa8313189c4 423 SUPERFAMILY SSF55681 3 318 9.0E-96 T 01-11-2018 MLA2C4_20895 f983fefda112761299d123aee7699d0b 213 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 75 210 9.4E-11 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_20895 f983fefda112761299d123aee7699d0b 213 Pfam PF00990 Diguanylate cyclase, GGDEF domain 81 211 2.2E-12 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_20895 f983fefda112761299d123aee7699d0b 213 SUPERFAMILY SSF55073 74 211 2.98E-13 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_20895 f983fefda112761299d123aee7699d0b 213 Gene3D G3DSA:3.30.70.270 68 213 1.6E-15 T 01-11-2018 MLA2C4_23495 993d753ae569754ed4a51e429c5188ce 149 Pfam PF10702 Protein of unknown function (DUF2507) 18 140 8.5E-49 T 01-11-2018 IPR019642 Protein of unknown function DUF2507 MLA2C4_23495 993d753ae569754ed4a51e429c5188ce 149 SUPERFAMILY SSF111126 15 128 8.37E-24 T 01-11-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily MLA2C4_23495 993d753ae569754ed4a51e429c5188ce 149 Gene3D G3DSA:3.30.1380.20 1 147 4.7E-54 T 01-11-2018 MLA2C4_21045 d55ebc43a38d91f542013bb94c822dcd 149 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_21045 d55ebc43a38d91f542013bb94c822dcd 149 Gene3D G3DSA:3.90.79.10 1 143 2.6E-37 T 01-11-2018 MLA2C4_21045 d55ebc43a38d91f542013bb94c822dcd 149 Pfam PF00293 NUDIX domain 21 142 2.4E-22 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_21045 d55ebc43a38d91f542013bb94c822dcd 149 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.7E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_21045 d55ebc43a38d91f542013bb94c822dcd 149 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.7E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_21045 d55ebc43a38d91f542013bb94c822dcd 149 SUPERFAMILY SSF55811 13 141 2.71E-32 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_07470 dab6c036381efec0d775c2f0660096cf 339 Gene3D G3DSA:3.20.20.140 58 317 3.4E-57 T 01-11-2018 MLA2C4_07470 dab6c036381efec0d775c2f0660096cf 339 SUPERFAMILY SSF89550 65 329 3.79E-35 T 01-11-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MLA2C4_07470 dab6c036381efec0d775c2f0660096cf 339 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 63 303 1.1E-28 T 01-11-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 MLA2C4_03730 bf209c60d37f44710ab423cb9a2071cc 489 PIRSF PIRSF005690 3 489 3.6E-166 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_03730 bf209c60d37f44710ab423cb9a2071cc 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 14 475 2.3E-170 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_27535 b93254b36f362fecc82627403627513c 165 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 139 7.1E-54 T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_27535 b93254b36f362fecc82627403627513c 165 Gene3D G3DSA:2.70.70.10 7 164 3.2E-60 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_27535 b93254b36f362fecc82627403627513c 165 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 79 91 - T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_27535 b93254b36f362fecc82627403627513c 165 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 17 137 2.2E-48 T 01-11-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MLA2C4_27535 b93254b36f362fecc82627403627513c 165 SUPERFAMILY SSF51261 8 153 3.66E-57 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 SUPERFAMILY SSF110710 21 199 2.28E-78 T 01-11-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 Hamap MF_00800 UPF0340 protein . 1 205 97.868 T 01-11-2018 IPR006340 Protein of unknown function DUF436 MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 Pfam PF04260 Protein of unknown function (DUF436) 26 195 5.8E-79 T 01-11-2018 IPR006340 Protein of unknown function DUF436 MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 PIRSF PIRSF007510 17 198 2.5E-79 T 01-11-2018 IPR006340 Protein of unknown function DUF436 MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 Gene3D G3DSA:3.40.50.10360 19 204 3.7E-81 T 01-11-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 27 199 2.0E-96 T 01-11-2018 IPR006340 Protein of unknown function DUF436 MLA2C4_27520 756143e562baf7ed538bee1b35864518 205 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 25 195 1.5E-75 T 01-11-2018 IPR006340 Protein of unknown function DUF436 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 SMART SM00387 273 384 2.0E-32 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 Pfam PF00512 His Kinase A (phospho-acceptor) domain 160 225 6.1E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 1.2E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 1.2E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 1.2E-9 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 SUPERFAMILY SSF47384 144 227 4.12E-19 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 SMART SM00388 160 227 9.5E-13 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 Gene3D G3DSA:1.10.287.130 104 223 4.5E-22 T 01-11-2018 MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 Gene3D G3DSA:3.30.565.10 236 384 6.8E-37 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 SUPERFAMILY SSF55874 216 380 8.91E-38 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_13525 1a0ec28cc84aa87534ed976c9335ff1b 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 382 1.3E-20 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_26375 1128c0c0b33366e80bb586ae7d12d0d4 146 Pfam PF07849 Protein of unknown function (DUF1641) 107 128 7.0E-5 T 01-11-2018 IPR012440 Protein of unknown function DUF1641 MLA2C4_26345 a7dbfffd1a490d528d94e75ec8803cdc 212 Pfam PF13460 NAD(P)H-binding 7 198 5.2E-24 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_26345 a7dbfffd1a490d528d94e75ec8803cdc 212 SUPERFAMILY SSF51735 1 209 1.18E-32 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_26345 a7dbfffd1a490d528d94e75ec8803cdc 212 Gene3D G3DSA:3.40.50.720 1 210 5.3E-53 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 SUPERFAMILY SSF49401 2489 2593 4.97E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1144 1235 5.1E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1278 1365 1.5E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3663 3754 1.2E-8 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 619 710 7.1E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3797 3890 9.2E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 4582 4675 7.1E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 487 576 9.4E-9 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3002 3085 2.9E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3929 4023 2.7E-6 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2214 2301 4.7E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2611 2690 5.5E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1541 1637 2.0E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1672 1758 3.1E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 750 844 1.2E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 4193 4283 1.9E-8 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2870 2958 2.5E-8 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1013 1101 8.2E-8 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2081 2167 4.5E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2738 2827 1.6E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1805 1893 3.0E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3533 3622 9.5E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 4712 4804 4.7E-9 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2479 2566 1.2E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3273 3359 1.3E-6 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3136 3232 1.2E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 3405 3485 1.9E-9 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 355 450 3.6E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 2346 2439 2.1E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 4450 4567 2.6E-8 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 1409 1498 4.9E-8 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Pfam PF01345 Domain of unknown function DUF11 882 967 6.7E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Gene3D G3DSA:2.60.40.740 3524 3656 5.0E-6 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Gene3D G3DSA:2.60.40.740 1529 1666 1.4E-5 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Gene3D G3DSA:2.60.40.740 1667 1781 6.4E-6 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Gene3D G3DSA:2.60.40.740 350 483 2.7E-5 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 Gene3D G3DSA:2.60.40.740 2078 2216 8.4E-6 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1146 1197 3.5E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4193 4245 2.3E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3137 3189 2.5E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3003 3054 2.2E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2479 2531 4.4E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3665 3717 8.0E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2215 2267 4.7E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1954 1993 1.2E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 752 804 5.4E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2347 2399 5.1E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3401 3453 2.3E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 488 540 2.5E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1806 1857 1.9E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4326 4370 8.9E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1014 1066 5.1E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3797 3849 2.8E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3929 3981 1.4E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 620 671 5.1E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 356 408 3.4E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1674 1726 1.1E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3271 3321 4.4E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4061 4112 5.8E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4450 4501 7.4E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1542 1594 7.2E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2871 2922 2.1E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1278 1330 4.6E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4855 4897 5.2E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4714 4765 3.3E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1410 1461 1.0E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2607 2659 1.2E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3533 3584 4.2E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 883 935 8.4E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2083 2134 5.4E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4582 4634 6.4E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2739 2790 5.9E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 SUPERFAMILY SSF88633 1532 1759 1.29E-7 T 01-11-2018 MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 SUPERFAMILY SSF49401 3407 3501 5.72E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 SUPERFAMILY SSF49401 3538 3633 6.21E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_08315 db62664e01aa2f3309ab55d032ddf425 5010 SUPERFAMILY SSF49401 3146 3237 5.22E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 SUPERFAMILY SSF53335 724 825 1.14E-15 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 Gene3D G3DSA:3.90.550.10 322 565 2.2E-39 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 SUPERFAMILY SSF53448 16 244 2.19E-45 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 Pfam PF08241 Methyltransferase domain 722 770 1.0E-10 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 Pfam PF00535 Glycosyl transferase family 2 19 148 5.5E-22 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 Pfam PF00535 Glycosyl transferase family 2 325 452 2.8E-21 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 Gene3D G3DSA:3.40.50.150 681 845 1.6E-18 T 01-11-2018 MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 Gene3D G3DSA:3.90.550.10 2 286 3.5E-45 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_09885 8fbc770f9f6d62b88fafe032cea212cf 853 SUPERFAMILY SSF53448 322 546 2.53E-44 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_16870 baf0e42520f38c6c63f31f2e6babcef9 203 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 146 202 9.7E-18 T 01-11-2018 IPR019240 Protein of unknown function DUF2196 MLA2C4_16870 baf0e42520f38c6c63f31f2e6babcef9 203 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 146 202 1.7E-20 T 01-11-2018 IPR019240 Protein of unknown function DUF2196 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 SUPERFAMILY SSF52540 8 142 3.82E-45 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 Gene3D G3DSA:3.30.60.20 142 194 5.4E-26 T 01-11-2018 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 Gene3D G3DSA:3.40.50.300 1 141 1.5E-63 T 01-11-2018 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.652 T 01-11-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 Pfam PF00265 Thymidine kinase 8 187 1.9E-60 T 01-11-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 SUPERFAMILY SSF57716 142 192 3.42E-16 T 01-11-2018 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 01-11-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MLA2C4_27595 e28f176923e5ce78532c6b077b717c09 194 PIRSF PIRSF035805 5 194 4.5E-68 T 01-11-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Pfam PF01131 DNA topoisomerase 152 583 3.9E-117 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 512 526 2.3E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 2.3E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 2.3E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 2.3E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 2.3E-25 T 01-11-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Gene3D G3DSA:3.40.50.140 3 154 2.0E-54 T 01-11-2018 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Gene3D G3DSA:1.10.460.10 160 593 3.9E-146 T 01-11-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 SMART SM00437 262 549 2.5E-82 T 01-11-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Gene3D G3DSA:2.70.20.10 210 477 3.9E-146 T 01-11-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Gene3D G3DSA:1.10.290.10 271 401 3.9E-146 T 01-11-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 SMART SM00436 126 216 2.0E-37 T 01-11-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 725 2.5E-263 T 01-11-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 638 72.06 T 01-11-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 SMART SM00493 3 126 6.7E-20 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 Pfam PF01751 Toprim domain 5 134 1.9E-16 T 01-11-2018 IPR006171 TOPRIM domain MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 SUPERFAMILY SSF56712 3 598 2.09E-177 T 01-11-2018 IPR023405 DNA topoisomerase, type IA, core domain MLA2C4_02215 c8288dc58bfc181dac86a13fd7b4fe0e 729 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 01-11-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MLA2C4_11630 679e5ed6f508ffab803903fc49a13e43 307 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 19 178 6.5E-16 T 01-11-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 MLA2C4_11630 679e5ed6f508ffab803903fc49a13e43 307 Pfam PF03837 RecT family 17 186 2.9E-33 T 01-11-2018 IPR018330 RecT family GO:0003677|GO:0006259 MLA2C4_28055 702fdaab3097ac808b04aefa3b27850a 351 Pfam PF00990 Diguanylate cyclase, GGDEF domain 191 346 1.1E-34 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_28055 702fdaab3097ac808b04aefa3b27850a 351 Pfam PF07694 5TMR of 5TMR-LYT 29 149 2.8E-13 T 01-11-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MLA2C4_28055 702fdaab3097ac808b04aefa3b27850a 351 SMART SM00267 180 350 1.4E-40 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_28055 702fdaab3097ac808b04aefa3b27850a 351 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 348 4.6E-40 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_28055 702fdaab3097ac808b04aefa3b27850a 351 Gene3D G3DSA:3.30.70.270 179 350 1.5E-45 T 01-11-2018 MLA2C4_28055 702fdaab3097ac808b04aefa3b27850a 351 SUPERFAMILY SSF55073 196 348 3.53E-38 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_27725 18a5b014dba277db53848fe97fd34830 300 SMART SM00382 29 205 2.6E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_27725 18a5b014dba277db53848fe97fd34830 300 SUPERFAMILY SSF52540 3 221 3.18E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27725 18a5b014dba277db53848fe97fd34830 300 Gene3D G3DSA:3.40.50.300 1 232 1.1E-66 T 01-11-2018 MLA2C4_27725 18a5b014dba277db53848fe97fd34830 300 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_27725 18a5b014dba277db53848fe97fd34830 300 Pfam PF00005 ABC transporter 20 156 2.1E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_10290 b811cf62d4d57d38685fdc08e0bb24c7 300 Gene3D G3DSA:3.20.20.100 3 300 2.2E-101 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_10290 b811cf62d4d57d38685fdc08e0bb24c7 300 Pfam PF00248 Aldo/keto reductase family 15 290 5.2E-60 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_10290 b811cf62d4d57d38685fdc08e0bb24c7 300 PRINTS PR00069 Aldo-keto reductase signature 112 130 3.9E-7 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_10290 b811cf62d4d57d38685fdc08e0bb24c7 300 PRINTS PR00069 Aldo-keto reductase signature 143 160 3.9E-7 T 01-11-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MLA2C4_10290 b811cf62d4d57d38685fdc08e0bb24c7 300 SUPERFAMILY SSF51430 8 295 7.86E-75 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_12435 70f04c0a8822fbe1b78393897c217a3d 242 Gene3D G3DSA:3.40.50.1820 1 235 1.9E-42 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12435 70f04c0a8822fbe1b78393897c217a3d 242 Pfam PF00561 alpha/beta hydrolase fold 13 130 1.4E-14 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12435 70f04c0a8822fbe1b78393897c217a3d 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 1.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12435 70f04c0a8822fbe1b78393897c217a3d 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 1.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12435 70f04c0a8822fbe1b78393897c217a3d 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.2E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12435 70f04c0a8822fbe1b78393897c217a3d 242 SUPERFAMILY SSF53474 3 234 3.62E-43 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_17920 5f49ea47a28cc878013ded1ac2917abb 257 ProSitePatterns PS00744 Beta-lactamases class B signature 2. 189 201 - T 01-11-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 MLA2C4_17920 5f49ea47a28cc878013ded1ac2917abb 257 Gene3D G3DSA:3.60.15.10 26 257 1.7E-81 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_17920 5f49ea47a28cc878013ded1ac2917abb 257 SUPERFAMILY SSF56281 46 256 1.97E-40 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_17920 5f49ea47a28cc878013ded1ac2917abb 257 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 113 132 - T 01-11-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 MLA2C4_17920 5f49ea47a28cc878013ded1ac2917abb 257 SMART SM00849 70 240 2.4E-22 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_17920 5f49ea47a28cc878013ded1ac2917abb 257 Pfam PF00753 Metallo-beta-lactamase superfamily 69 221 8.3E-13 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_19095 6d2cba6f6cd65fac8ded8ebf504f87e4 121 Pfam PF03788 LrgA family 18 109 1.8E-30 T 01-11-2018 IPR005538 LrgA/CidA family GO:0016021 MLA2C4_19095 6d2cba6f6cd65fac8ded8ebf504f87e4 121 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 118 24.161 T 01-11-2018 IPR023760 Holin-like protein CidA GO:0016021 MLA2C4_03330 f9e48ddf9b66f486bc83c8dc72ec8d7a 374 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 373 6.1E-94 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_03330 f9e48ddf9b66f486bc83c8dc72ec8d7a 374 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 371 6.3E-31 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_03330 f9e48ddf9b66f486bc83c8dc72ec8d7a 374 Gene3D G3DSA:3.30.300.210 223 374 1.3E-21 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_11460 aeae97b687428a2a44d8f2f2ee954ec4 249 Pfam PF14344 Domain of unknown function (DUF4397) 61 173 7.5E-29 T 01-11-2018 IPR025510 Domain of unknown function DUF4397 MLA2C4_11460 aeae97b687428a2a44d8f2f2ee954ec4 249 Pfam PF14344 Domain of unknown function (DUF4397) 166 248 2.7E-7 T 01-11-2018 IPR025510 Domain of unknown function DUF4397 MLA2C4_14700 c3ba0796e22f9601249b71ba5d25bdee 332 Gene3D G3DSA:3.40.50.970 2 332 4.0E-127 T 01-11-2018 MLA2C4_14700 c3ba0796e22f9601249b71ba5d25bdee 332 Pfam PF00676 Dehydrogenase E1 component 23 319 1.3E-94 T 01-11-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MLA2C4_14700 c3ba0796e22f9601249b71ba5d25bdee 332 SUPERFAMILY SSF52518 10 330 2.86E-104 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 ProSitePatterns PS00818 Dps protein family signature 1. 29 45 - T 01-11-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 1.7E-13 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 1.7E-13 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 29 45 1.7E-13 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 Gene3D G3DSA:1.20.1260.10 2 147 1.6E-57 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 Pfam PF00210 Ferritin-like domain 9 146 5.5E-36 T 01-11-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 PIRSF PIRSF005900 1 147 1.6E-51 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_10250 08abec9deca279fb6e376bbd973e08fd 147 SUPERFAMILY SSF47240 7 146 1.99E-48 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_13790 6d03159c1959a42bc25bac34ffd31158 56 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 8 49 4.0E-5 T 01-11-2018 IPR019241 Protein of unknown function DUF2197 MLA2C4_06115 01360c865c4df76fcbfe8695baffe227 284 PIRSF PIRSF012524 1 284 3.4E-102 T 01-11-2018 IPR014464 Conserved virulence factor B MLA2C4_06115 01360c865c4df76fcbfe8695baffe227 284 SUPERFAMILY SSF50249 154 213 4.5E-5 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_06115 01360c865c4df76fcbfe8695baffe227 284 Gene3D G3DSA:2.40.50.140 153 219 9.3E-17 T 01-11-2018 MLA2C4_06115 01360c865c4df76fcbfe8695baffe227 284 Gene3D G3DSA:2.40.50.140 73 149 1.7E-22 T 01-11-2018 MLA2C4_06115 01360c865c4df76fcbfe8695baffe227 284 Pfam PF13509 S1 domain 5 64 3.2E-18 T 01-11-2018 IPR039566 Conserved virulence factor B, S1 domain MLA2C4_06115 01360c865c4df76fcbfe8695baffe227 284 Gene3D G3DSA:1.10.10.10 221 282 1.1E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26805 d42589741b8e65fe3708c5dc22884ffd 400 Gene3D G3DSA:2.30.42.10 276 378 2.7E-7 T 01-11-2018 MLA2C4_26805 d42589741b8e65fe3708c5dc22884ffd 400 SUPERFAMILY SSF50156 306 390 6.52E-12 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 Gene3D G3DSA:1.10.357.10 71 193 4.7E-22 T 01-11-2018 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.2E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.2E-6 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 SUPERFAMILY SSF48498 79 192 1.07E-22 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 Gene3D G3DSA:1.10.10.60 1 65 2.9E-27 T 01-11-2018 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.9E-14 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 SUPERFAMILY SSF46689 2 82 3.18E-17 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_17185 f76082ddf7107bc00b3ee18585effa8b 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_09795 140277c68222133648b86e79cee10d6a 138 Gene3D G3DSA:3.10.129.10 1 135 1.9E-44 T 01-11-2018 MLA2C4_09795 140277c68222133648b86e79cee10d6a 138 SUPERFAMILY SSF54637 7 136 1.22E-42 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_09795 140277c68222133648b86e79cee10d6a 138 Pfam PF01575 MaoC like domain 11 106 7.3E-28 T 01-11-2018 IPR002539 MaoC-like dehydratase domain MLA2C4_14470 cf2f39074bedf72d5c37df47aa25b980 225 Pfam PF00005 ABC transporter 24 170 3.1E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_14470 cf2f39074bedf72d5c37df47aa25b980 225 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_14470 cf2f39074bedf72d5c37df47aa25b980 225 Gene3D G3DSA:3.40.50.300 1 224 7.0E-63 T 01-11-2018 MLA2C4_14470 cf2f39074bedf72d5c37df47aa25b980 225 SUPERFAMILY SSF52540 3 221 5.86E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14470 cf2f39074bedf72d5c37df47aa25b980 225 SMART SM00382 33 219 7.4E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 SUPERFAMILY SSF51690 109 275 2.43E-57 T 01-11-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 PIRSF PIRSF006250 1 277 1.6E-96 T 01-11-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 107 2.5E-25 T 01-11-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 275 4.0E-100 T 01-11-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 Gene3D G3DSA:3.90.1170.20 14 272 1.5E-102 T 01-11-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 Gene3D G3DSA:3.20.20.70 123 265 1.5E-102 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 273 6.1E-62 T 01-11-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 MLA2C4_23095 daa5f25da51eb3cacb21619e0eaa5799 277 SUPERFAMILY SSF54675 2 108 3.49E-29 T 01-11-2018 MLA2C4_27435 b9203c5beea93b0da7bc5395ce977e26 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 122 19.578 T 01-11-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 MLA2C4_27435 b9203c5beea93b0da7bc5395ce977e26 122 Gene3D G3DSA:1.20.58.1610 1 121 4.2E-43 T 01-11-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27435 b9203c5beea93b0da7bc5395ce977e26 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 121 1.6E-37 T 01-11-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 Pfam PF00463 Isocitrate lyase family 248 423 4.2E-48 T 01-11-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 Pfam PF00463 Isocitrate lyase family 11 247 7.3E-56 T 01-11-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 Gene3D G3DSA:3.20.20.60 4 406 3.6E-172 T 01-11-2018 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 6 248 3.9E-107 T 01-11-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 SUPERFAMILY SSF51621 5 423 1.48E-155 T 01-11-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 PIRSF PIRSF001362 1 425 6.9E-240 T 01-11-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MLA2C4_05940 53a1f77d5f9b82316b218d087acf88f7 425 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 01-11-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 Pfam PF12833 Helix-turn-helix domain 30 107 1.5E-23 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 60 102 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 Gene3D G3DSA:2.60.120.260 113 275 3.6E-17 T 01-11-2018 IPR008979 Galactose-binding-like domain superfamily MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 SUPERFAMILY SSF46689 59 110 7.17E-14 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 Gene3D G3DSA:1.10.10.60 2 59 2.8E-18 T 01-11-2018 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 90 1.2E-6 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 90 106 1.2E-6 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 SMART SM00342 23 106 4.4E-30 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 Gene3D G3DSA:1.10.10.60 60 112 1.0E-16 T 01-11-2018 MLA2C4_01110 0b4c0d6423fbf021fab854cb38b01f1b 299 SUPERFAMILY SSF46689 7 57 3.14E-11 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_18400 9d6258e13d2094b80706b46597e85e1d 113 Pfam PF04266 ASCH domain 6 112 6.1E-16 T 01-11-2018 IPR007374 ASCH domain MLA2C4_18400 9d6258e13d2094b80706b46597e85e1d 113 PIRSF PIRSF016134 1 113 2.4E-44 T 01-11-2018 IPR016645 Uncharacterised conserved protein UCP016134 MLA2C4_18400 9d6258e13d2094b80706b46597e85e1d 113 SMART SM01022 5 113 7.1E-16 T 01-11-2018 IPR007374 ASCH domain MLA2C4_18400 9d6258e13d2094b80706b46597e85e1d 113 SUPERFAMILY SSF88697 1 112 3.81E-36 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_18400 9d6258e13d2094b80706b46597e85e1d 113 Gene3D G3DSA:2.30.130.30 1 113 7.8E-34 T 01-11-2018 MLA2C4_27065 5eceea3d233319919e4879c31149ee58 294 Pfam PF01063 Amino-transferase class IV 39 259 5.0E-45 T 01-11-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MLA2C4_27065 5eceea3d233319919e4879c31149ee58 294 Gene3D G3DSA:3.30.470.10 3 127 2.0E-29 T 01-11-2018 MLA2C4_27065 5eceea3d233319919e4879c31149ee58 294 ProSitePatterns PS00770 Aminotransferases class-IV signature. 187 216 - T 01-11-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MLA2C4_27065 5eceea3d233319919e4879c31149ee58 294 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 11 286 4.5E-101 T 01-11-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 MLA2C4_27065 5eceea3d233319919e4879c31149ee58 294 SUPERFAMILY SSF56752 24 282 1.57E-74 T 01-11-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MLA2C4_27065 5eceea3d233319919e4879c31149ee58 294 Gene3D G3DSA:3.20.10.10 134 290 2.4E-57 T 01-11-2018 MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.1E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.1E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.1E-6 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 Gene3D G3DSA:1.10.10.10 3 143 2.4E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 SMART SM00347 27 124 2.5E-21 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 SUPERFAMILY SSF46785 9 138 2.66E-30 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_09855 d11fd33607c7167447bcedd335144aaa 147 Pfam PF01047 MarR family 34 85 3.2E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 SMART SM00936 299 400 9.5E-9 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 Gene3D G3DSA:3.40.710.10 21 299 5.7E-82 T 01-11-2018 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 400 1.3E-15 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 Gene3D G3DSA:2.60.410.10 300 400 9.8E-15 T 01-11-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 7.7E-10 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 7.7E-10 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 7.7E-10 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 SUPERFAMILY SSF56601 1 299 1.03E-74 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 279 4.6E-69 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_27925 f23131e58facc33e3c3b928502b99328 423 SUPERFAMILY SSF69189 291 380 7.46E-15 T 01-11-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_04950 b8a1b538ba9c7c892579f6354156af30 844 Gene3D G3DSA:3.30.920.90 330 481 2.4E-16 T 01-11-2018 MLA2C4_04950 b8a1b538ba9c7c892579f6354156af30 844 Gene3D G3DSA:3.40.50.300 506 687 3.6E-21 T 01-11-2018 MLA2C4_04950 b8a1b538ba9c7c892579f6354156af30 844 Pfam PF07728 AAA domain (dynein-related subfamily) 523 674 1.7E-7 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MLA2C4_04950 b8a1b538ba9c7c892579f6354156af30 844 SUPERFAMILY SSF52540 516 686 8.59E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04950 b8a1b538ba9c7c892579f6354156af30 844 Pfam PF12102 Domain of unknown function (DUF3578) 293 464 3.9E-56 T 01-11-2018 IPR021961 Protein of unknown function DUF3578 MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Gene3D G3DSA:2.40.128.540 352 492 4.4E-62 T 01-11-2018 MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Pfam PF16103 Domain of unknown function (DUF4822) 228 347 1.2E-53 T 01-11-2018 IPR032247 Domain of unknown function DUF4822 MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Pfam PF16103 Domain of unknown function (DUF4822) 368 490 9.6E-52 T 01-11-2018 IPR032247 Domain of unknown function DUF4822 MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Gene3D G3DSA:2.40.128.540 220 351 4.7E-58 T 01-11-2018 MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Pfam PF00395 S-layer homology domain 102 146 2.5E-9 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Pfam PF00395 S-layer homology domain 162 205 1.1E-9 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_18895 e63a4ba345131726f70be5d3d936cc93 492 Pfam PF00395 S-layer homology domain 42 84 3.6E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05350 01d47594aae2a98a5557800bad5b1c96 176 Pfam PF11181 Heat induced stress protein YflT 8 60 1.9E-7 T 01-11-2018 IPR025889 General stress protein 17M-like domain MLA2C4_15010 532653187e951aaef88c0594fb982ecb 110 SUPERFAMILY SSF54292 19 109 2.75E-23 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MLA2C4_15010 532653187e951aaef88c0594fb982ecb 110 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 95 2.0E-27 T 01-11-2018 MLA2C4_15010 532653187e951aaef88c0594fb982ecb 110 Gene3D G3DSA:3.10.20.440 7 102 9.0E-23 T 01-11-2018 MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 Gene3D G3DSA:1.10.1740.10 7 93 4.9E-13 T 01-11-2018 MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 175 8.0E-16 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 Gene3D G3DSA:1.10.10.10 109 178 1.0E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 Pfam PF04542 Sigma-70 region 2 27 94 5.8E-6 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 SUPERFAMILY SSF88659 121 178 1.7E-12 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 SUPERFAMILY SSF88946 7 107 1.57E-12 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_08460 7267bf4f82cafacd8948d70e2ef9690d 181 Pfam PF08281 Sigma-70, region 4 121 173 1.6E-11 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_22415 e2bcda5a02a524ef8bee0b42c4745296 373 Gene3D G3DSA:3.40.1390.30 6 129 1.1E-39 T 01-11-2018 MLA2C4_22415 e2bcda5a02a524ef8bee0b42c4745296 373 Gene3D G3DSA:3.30.70.120 133 242 4.3E-48 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_22415 e2bcda5a02a524ef8bee0b42c4745296 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 352 8.7E-85 T 01-11-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MLA2C4_22415 e2bcda5a02a524ef8bee0b42c4745296 373 PIRSF PIRSF037489 4 373 4.2E-163 T 01-11-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria MLA2C4_22415 e2bcda5a02a524ef8bee0b42c4745296 373 SUPERFAMILY SSF102705 7 372 2.09E-136 T 01-11-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily MLA2C4_22415 e2bcda5a02a524ef8bee0b42c4745296 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 368 5.4E-88 T 01-11-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MLA2C4_24825 9fb06b5f662223fabd334ab972e2d52f 127 Pfam PF03899 ATP synthase I chain 13 102 1.9E-13 T 01-11-2018 IPR005598 ATP synthase protein I MLA2C4_24825 9fb06b5f662223fabd334ab972e2d52f 127 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 27 123 9.0E-51 T 01-11-2018 MLA2C4_16075 9e87f195ca71579e45b3bfd036cf195d 247 SUPERFAMILY SSF56300 1 232 7.45E-52 T 01-11-2018 MLA2C4_16075 9e87f195ca71579e45b3bfd036cf195d 247 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 192 9.0E-24 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MLA2C4_16075 9e87f195ca71579e45b3bfd036cf195d 247 Gene3D G3DSA:3.60.21.10 1 245 2.2E-62 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_16075 9e87f195ca71579e45b3bfd036cf195d 247 PIRSF PIRSF000883 2 243 2.1E-56 T 01-11-2018 IPR011152 Phosphoesterase MJ0912 MLA2C4_11445 6898501f1846f4f4b38146987540a515 474 SUPERFAMILY SSF53720 3 473 8.12E-153 T 01-11-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MLA2C4_11445 6898501f1846f4f4b38146987540a515 474 Gene3D G3DSA:3.40.309.10 250 440 2.7E-159 T 01-11-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MLA2C4_11445 6898501f1846f4f4b38146987540a515 474 Pfam PF00171 Aldehyde dehydrogenase family 19 470 5.4E-163 T 01-11-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MLA2C4_11445 6898501f1846f4f4b38146987540a515 474 Gene3D G3DSA:3.40.605.10 25 461 2.7E-159 T 01-11-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 SMART SM00418 17 96 6.4E-20 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 SUPERFAMILY SSF46785 5 95 1.25E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 Gene3D G3DSA:1.10.10.10 2 95 5.2E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.3E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.3E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 2.3E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_22265 a661e67b414ec238d7e0f1b343fe69d3 96 Pfam PF12840 Helix-turn-helix domain 16 75 9.0E-10 T 01-11-2018 MLA2C4_08245 5aeda7a6fed6082c496fd94bccd55b94 1219 Pfam PF00350 Dynamin family 46 200 5.3E-31 T 01-11-2018 IPR022812 Dynamin superfamily MLA2C4_08245 5aeda7a6fed6082c496fd94bccd55b94 1219 Pfam PF00350 Dynamin family 624 850 1.8E-46 T 01-11-2018 IPR022812 Dynamin superfamily MLA2C4_08245 5aeda7a6fed6082c496fd94bccd55b94 1219 Gene3D G3DSA:3.40.50.300 46 276 7.1E-42 T 01-11-2018 MLA2C4_08245 5aeda7a6fed6082c496fd94bccd55b94 1219 SUPERFAMILY SSF52540 607 890 2.38E-32 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08245 5aeda7a6fed6082c496fd94bccd55b94 1219 SUPERFAMILY SSF52540 32 258 3.46E-31 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_20960 8a33699408d4d27f3c340f743a426785 387 Pfam PF00155 Aminotransferase class I and II 29 377 1.7E-69 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_20960 8a33699408d4d27f3c340f743a426785 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MLA2C4_20960 8a33699408d4d27f3c340f743a426785 387 SUPERFAMILY SSF53383 4 382 3.9E-114 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_20960 8a33699408d4d27f3c340f743a426785 387 Gene3D G3DSA:3.40.640.10 58 280 2.6E-127 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_20960 8a33699408d4d27f3c340f743a426785 387 Gene3D G3DSA:3.90.1150.10 29 377 2.6E-127 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_09100 8c28f35c9a5789d572d803e67256aa06 381 PRINTS PR00164 ABC-2 type transport system membrane protein signature 262 286 5.5E-5 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MLA2C4_09100 8c28f35c9a5789d572d803e67256aa06 381 PRINTS PR00164 ABC-2 type transport system membrane protein signature 299 318 5.5E-5 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MLA2C4_09100 8c28f35c9a5789d572d803e67256aa06 381 Gene3D G3DSA:3.40.1710.10 44 146 2.5E-7 T 01-11-2018 MLA2C4_09100 8c28f35c9a5789d572d803e67256aa06 381 Pfam PF12698 ABC-2 family transporter protein 19 369 1.6E-42 T 01-11-2018 MLA2C4_12155 ebb2037c0f466e0c3427f13ab13a18c9 79 Pfam PF10763 Protein of unknown function (DUF2584) 1 79 9.0E-29 T 01-11-2018 IPR019699 Protein of unknown function DUF2584 MLA2C4_12155 ebb2037c0f466e0c3427f13ab13a18c9 79 SUPERFAMILY SSF88697 1 79 1.44E-20 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_12155 ebb2037c0f466e0c3427f13ab13a18c9 79 Gene3D G3DSA:2.40.240.20 1 76 1.4E-27 T 01-11-2018 MLA2C4_24700 6b44ee30a4860c59eb7c35597e0f3cfd 319 SUPERFAMILY SSF102114 5 308 1.15E-52 T 01-11-2018 MLA2C4_24700 6b44ee30a4860c59eb7c35597e0f3cfd 319 Pfam PF04055 Radical SAM superfamily 52 214 1.5E-14 T 01-11-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MLA2C4_24700 6b44ee30a4860c59eb7c35597e0f3cfd 319 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 312 1.1E-127 T 01-11-2018 IPR005911 Protein YhcC-like GO:0051536 MLA2C4_24700 6b44ee30a4860c59eb7c35597e0f3cfd 319 Gene3D G3DSA:3.20.20.70 49 258 1.4E-13 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_24700 6b44ee30a4860c59eb7c35597e0f3cfd 319 SMART SM00729 32 259 2.8E-42 T 01-11-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MLA2C4_24700 6b44ee30a4860c59eb7c35597e0f3cfd 319 Pfam PF16199 Radical_SAM C-terminal domain 220 302 4.2E-25 T 01-11-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 SUPERFAMILY SSF51645 6 528 3.14E-199 T 01-11-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 Gene3D G3DSA:3.20.20.360 2 407 3.9E-205 T 01-11-2018 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 Pfam PF01274 Malate synthase 14 527 2.2E-217 T 01-11-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 Gene3D G3DSA:1.20.1220.12 408 529 2.3E-51 T 01-11-2018 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 PIRSF PIRSF001363 1 529 8.2E-266 T 01-11-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 01-11-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MLA2C4_05935 dc0ebc34887f3462af270aff2d5dbfe9 529 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 21 529 4.6E-255 T 01-11-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MLA2C4_16620 c48b787735070471835d6016fea4a32e 151 PIRSF PIRSF005859 1 151 4.9E-39 T 01-11-2018 IPR004307 TspO/MBR-related protein GO:0016021 MLA2C4_16620 c48b787735070471835d6016fea4a32e 151 Pfam PF03073 TspO/MBR family 9 148 1.3E-30 T 01-11-2018 IPR004307 TspO/MBR-related protein GO:0016021 MLA2C4_16620 c48b787735070471835d6016fea4a32e 151 Gene3D G3DSA:1.20.1260.100 2 151 2.1E-29 T 01-11-2018 IPR038330 TspO/MBR-related superfamily MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 Pfam PF00106 short chain dehydrogenase 7 200 7.3E-68 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 7 247 6.7E-94 T 01-11-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 8.2E-5 T 01-11-2018 MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.8E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.8E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.8E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.8E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.8E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.8E-45 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 Gene3D G3DSA:3.40.50.720 1 246 9.0E-88 T 01-11-2018 MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 SUPERFAMILY SSF51735 5 247 3.56E-87 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06990 9a44195cd0b154c82f7cbf954a1b71d0 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.0E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_06795 f3fd873b26be984424d5f19d83e84962 428 SUPERFAMILY SSF56601 4 286 2.73E-59 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_06795 f3fd873b26be984424d5f19d83e84962 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 125 142 1.7E-10 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_06795 f3fd873b26be984424d5f19d83e84962 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 75 86 1.7E-10 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_06795 f3fd873b26be984424d5f19d83e84962 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 152 165 1.7E-10 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_06795 f3fd873b26be984424d5f19d83e84962 428 Gene3D G3DSA:3.40.710.10 22 317 3.7E-76 T 01-11-2018 MLA2C4_06795 f3fd873b26be984424d5f19d83e84962 428 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 266 7.0E-49 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_01535 be4a1da7766bc47b2db71aa594afd951 230 SUPERFAMILY SSF53067 1 101 1.12E-28 T 01-11-2018 MLA2C4_01535 be4a1da7766bc47b2db71aa594afd951 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 1.6E-56 T 01-11-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MLA2C4_01535 be4a1da7766bc47b2db71aa594afd951 230 Gene3D G3DSA:3.30.420.40 95 189 2.0E-50 T 01-11-2018 MLA2C4_01535 be4a1da7766bc47b2db71aa594afd951 230 Gene3D G3DSA:3.30.420.40 3 216 2.0E-50 T 01-11-2018 MLA2C4_01535 be4a1da7766bc47b2db71aa594afd951 230 Pfam PF00814 Glycoprotease family 32 224 3.1E-36 T 01-11-2018 IPR000905 Gcp-like domain MLA2C4_01535 be4a1da7766bc47b2db71aa594afd951 230 SUPERFAMILY SSF53067 108 214 6.21E-15 T 01-11-2018 MLA2C4_21265 3e1b623dc297ce36f729fc6097cc7b7b 490 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 22 479 1.1E-152 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_21265 3e1b623dc297ce36f729fc6097cc7b7b 490 PIRSF PIRSF005690 7 490 2.3E-137 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_17605 aca1492cf722c9eff22b3f46e93401ae 152 SUPERFAMILY SSF118196 3 151 1.83E-43 T 01-11-2018 IPR036413 YaeB-like superfamily MLA2C4_17605 aca1492cf722c9eff22b3f46e93401ae 152 Pfam PF01980 Uncharacterised protein family UPF0066 28 133 2.8E-29 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain MLA2C4_17605 aca1492cf722c9eff22b3f46e93401ae 152 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 26 138 5.9E-31 T 01-11-2018 IPR023370 YaeB-like, N-terminal domain MLA2C4_17605 aca1492cf722c9eff22b3f46e93401ae 152 Gene3D G3DSA:2.40.30.70 5 150 4.6E-34 T 01-11-2018 IPR036414 YaeB, N-terminal domain superfamily MLA2C4_00320 e869a53a17650dbac309029c58bc00ba 91 Gene3D G3DSA:3.10.290.10 1 89 2.4E-24 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_00320 e869a53a17650dbac309029c58bc00ba 91 PIRSF PIRSF038881 1 88 4.7E-36 T 01-11-2018 IPR025490 RNA-binding protein, HP1423 type MLA2C4_00320 e869a53a17650dbac309029c58bc00ba 91 SUPERFAMILY SSF55174 1 77 1.96E-20 T 01-11-2018 MLA2C4_00320 e869a53a17650dbac309029c58bc00ba 91 Pfam PF01479 S4 domain 1 46 1.3E-10 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00320 e869a53a17650dbac309029c58bc00ba 91 SMART SM00363 1 64 4.0E-9 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 Gene3D G3DSA:3.30.70.2520 302 394 4.7E-26 T 01-11-2018 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 PIRSF PIRSF000136 1 437 2.3E-165 T 01-11-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 20 53 - T 01-11-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 Pfam PF04030 D-arabinono-1,4-lactone oxidase 179 429 3.2E-79 T 01-11-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 9 431 5.2E-122 T 01-11-2018 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 Gene3D G3DSA:3.30.43.10 4 72 1.1E-20 T 01-11-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 Gene3D G3DSA:3.30.465.10 74 198 4.8E-35 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 SUPERFAMILY SSF56176 7 185 3.69E-49 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_03580 076475698a51eb48b60e3c7419931fe0 437 Pfam PF01565 FAD binding domain 20 155 8.4E-30 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Pfam PF00994 Probable molybdopterin binding domain 190 325 6.8E-24 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 SUPERFAMILY SSF63882 7 184 6.28E-50 T 01-11-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Pfam PF03454 MoeA C-terminal region (domain IV) 339 410 4.8E-14 T 01-11-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 175 4.1E-38 T 01-11-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Gene3D G3DSA:3.90.105.10 26 182 9.2E-116 T 01-11-2018 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Gene3D G3DSA:2.40.340.10 336 403 9.2E-116 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 SMART SM00852 188 326 1.0E-34 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 SUPERFAMILY SSF63867 337 412 2.62E-16 T 01-11-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 185 322 1.1E-30 T 01-11-2018 IPR001453 MoaB/Mog domain MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Gene3D G3DSA:2.170.190.11 49 149 9.2E-116 T 01-11-2018 MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 Gene3D G3DSA:3.40.980.10 183 335 9.2E-116 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_18510 30920ef8dbe36b0d533335fdd3f6a029 435 SUPERFAMILY SSF53218 186 327 7.85E-38 T 01-11-2018 IPR036425 MoaB/Mog-like domain superfamily MLA2C4_26425 3cd3990afd390eeb6b0b003799092ca1 77 Pfam PF13127 Protein of unknown function (DUF3955) 11 68 2.0E-16 T 01-11-2018 IPR025016 Protein of unknown function DUF3955 MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 SUPERFAMILY SSF46785 17 100 6.96E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 Gene3D G3DSA:1.10.10.10 2 109 1.1E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 7.7E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 7.7E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 7.7E-14 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 SMART SM00418 22 101 3.6E-16 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18195 d0f84976f286afc72a08f9fb9bcf66fb 114 Pfam PF01022 Bacterial regulatory protein, arsR family 29 77 1.1E-12 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_21945 321b86d4cc364e25f357235716506a4d 192 SUPERFAMILY SSF55729 3 138 6.82E-22 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21945 321b86d4cc364e25f357235716506a4d 192 Gene3D G3DSA:3.40.630.30 1 160 3.2E-25 T 01-11-2018 MLA2C4_21945 321b86d4cc364e25f357235716506a4d 192 Pfam PF13302 Acetyltransferase (GNAT) domain 4 138 6.9E-16 T 01-11-2018 IPR000182 GNAT domain MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.3E-12 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.3E-12 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.3E-12 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.3E-12 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 318 1.3E-43 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 SUPERFAMILY SSF51905 152 332 2.45E-20 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 SUPERFAMILY SSF51905 1 207 2.86E-29 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 Gene3D G3DSA:3.50.50.100 1 391 1.6E-115 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.5E-7 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 6.5E-7 T 01-11-2018 MLA2C4_26380 142a4276ce6fb7f3d1f14c2720a6f1cf 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 6.5E-7 T 01-11-2018 MLA2C4_23190 5036a1f0232170ca7bde935db3fbeec4 265 SUPERFAMILY SSF52540 5 260 6.1E-61 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23190 5036a1f0232170ca7bde935db3fbeec4 265 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 218 2.9E-26 T 01-11-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MLA2C4_23190 5036a1f0232170ca7bde935db3fbeec4 265 PIRSF PIRSF003092 1 265 8.9E-93 T 01-11-2018 IPR025501 ATP binding protein MinD MLA2C4_23190 5036a1f0232170ca7bde935db3fbeec4 265 Gene3D G3DSA:3.40.50.300 3 254 1.6E-72 T 01-11-2018 MLA2C4_23190 5036a1f0232170ca7bde935db3fbeec4 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 262 1.6E-122 T 01-11-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 MLA2C4_18055 7b1ef63202606443cd3dbb5c038ce51f 302 SUPERFAMILY SSF53807 40 300 2.98E-47 T 01-11-2018 MLA2C4_18055 7b1ef63202606443cd3dbb5c038ce51f 302 Pfam PF01497 Periplasmic binding protein 70 279 7.3E-30 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_18055 7b1ef63202606443cd3dbb5c038ce51f 302 Gene3D G3DSA:3.40.50.1980 142 302 3.8E-37 T 01-11-2018 MLA2C4_18055 7b1ef63202606443cd3dbb5c038ce51f 302 Gene3D G3DSA:3.40.50.1980 24 141 1.5E-16 T 01-11-2018 MLA2C4_07385 206219f315b9f186850c4cfa26b6d3bc 298 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 289 2.3E-103 T 01-11-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 MLA2C4_07385 206219f315b9f186850c4cfa26b6d3bc 298 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 01-11-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MLA2C4_07385 206219f315b9f186850c4cfa26b6d3bc 298 Gene3D G3DSA:3.20.10.10 125 295 9.6E-55 T 01-11-2018 MLA2C4_07385 206219f315b9f186850c4cfa26b6d3bc 298 SUPERFAMILY SSF56752 4 291 3.4E-94 T 01-11-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MLA2C4_07385 206219f315b9f186850c4cfa26b6d3bc 298 Gene3D G3DSA:3.30.470.10 1 124 1.1E-47 T 01-11-2018 MLA2C4_07385 206219f315b9f186850c4cfa26b6d3bc 298 Pfam PF01063 Amino-transferase class IV 32 258 4.3E-60 T 01-11-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MLA2C4_06535 0ea1c82b95945e5fa1348f0f724ce7dc 227 Pfam PF10042 Uncharacterized conserved protein (DUF2278) 1 212 5.6E-74 T 01-11-2018 IPR019268 Protein of unknown function DUF2278 MLA2C4_20975 cff85f7900c19f9b35fb5336bf44b12f 433 Gene3D G3DSA:1.10.3720.10 176 433 3.6E-68 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_20975 cff85f7900c19f9b35fb5336bf44b12f 433 SUPERFAMILY SSF161098 180 417 5.63E-57 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_20975 cff85f7900c19f9b35fb5336bf44b12f 433 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 215 419 2.7E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_20975 cff85f7900c19f9b35fb5336bf44b12f 433 SUPERFAMILY SSF160964 85 185 4.32E-10 T 01-11-2018 MLA2C4_14755 d2a2fb614198dbc64ba253c154290e7f 278 SUPERFAMILY SSF161098 87 270 3.66E-38 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_14755 d2a2fb614198dbc64ba253c154290e7f 278 Gene3D G3DSA:1.10.3720.10 85 275 2.8E-34 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_14755 d2a2fb614198dbc64ba253c154290e7f 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 270 1.3E-24 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_11860 82f4ab6ecf82f3930a1cd9b515177621 331 SUPERFAMILY SSF69279 19 129 1.28E-7 T 01-11-2018 MLA2C4_09135 535961d635473cfb5d7a8f9d34fa935e 247 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 237 6.1E-94 T 01-11-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MLA2C4_09135 535961d635473cfb5d7a8f9d34fa935e 247 PIRSF PIRSF005650 1 247 1.8E-80 T 01-11-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MLA2C4_09135 535961d635473cfb5d7a8f9d34fa935e 247 SUPERFAMILY SSF53633 3 237 5.24E-59 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_09135 535961d635473cfb5d7a8f9d34fa935e 247 Hamap MF_01220_B Uridylate kinase [pyrH]. 2 237 36.803 T 01-11-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MLA2C4_09135 535961d635473cfb5d7a8f9d34fa935e 247 Gene3D G3DSA:3.40.1160.10 1 247 1.0E-76 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_09135 535961d635473cfb5d7a8f9d34fa935e 247 Pfam PF00696 Amino acid kinase family 5 216 1.0E-23 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MLA2C4_14610 4685d28c277f3914121864056e3d81b4 209 SUPERFAMILY SSF102198 4 206 1.12E-60 T 01-11-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_14610 4685d28c277f3914121864056e3d81b4 209 TIGRFAM TIGR03035 trp_arylform: arylformamidase 6 209 8.2E-99 T 01-11-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_14610 4685d28c277f3914121864056e3d81b4 209 Hamap MF_01969 Kynurenine formamidase [kynB]. 5 209 43.104 T 01-11-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_14610 4685d28c277f3914121864056e3d81b4 209 Pfam PF04199 Putative cyclase 7 152 9.5E-22 T 01-11-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_14610 4685d28c277f3914121864056e3d81b4 209 Gene3D G3DSA:3.50.30.50 1 209 1.3E-82 T 01-11-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MLA2C4_19695 701d5f566e3174b4510ddc7a559ed6dc 328 Gene3D G3DSA:3.60.60.10 2 328 5.1E-117 T 01-11-2018 MLA2C4_19695 701d5f566e3174b4510ddc7a559ed6dc 328 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 315 2.4E-110 T 01-11-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal MLA2C4_19695 701d5f566e3174b4510ddc7a559ed6dc 328 SUPERFAMILY SSF56235 2 328 6.1E-116 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_20580 cfcfb4893fa6ad4541d5d499d3dca950 301 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 3 283 3.8E-142 T 01-11-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG MLA2C4_20580 cfcfb4893fa6ad4541d5d499d3dca950 301 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 281 3.9E-62 T 01-11-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MLA2C4_19750 aea55e4d1a5e0cb8f94300785a14af91 264 SUPERFAMILY SSF56300 1 256 1.35E-89 T 01-11-2018 MLA2C4_19750 aea55e4d1a5e0cb8f94300785a14af91 264 Pfam PF13277 YmdB-like protein 4 254 1.3E-108 T 01-11-2018 IPR005235 Metallophosphoesterase, YmdB-like MLA2C4_19750 aea55e4d1a5e0cb8f94300785a14af91 264 PIRSF PIRSF004789 1 263 2.0E-101 T 01-11-2018 IPR005235 Metallophosphoesterase, YmdB-like MLA2C4_19750 aea55e4d1a5e0cb8f94300785a14af91 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 7.2E-113 T 01-11-2018 IPR005235 Metallophosphoesterase, YmdB-like MLA2C4_19750 aea55e4d1a5e0cb8f94300785a14af91 264 Gene3D G3DSA:3.60.21.10 1 264 6.0E-115 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_17945 9d981f95a44490d550c1a96116436a51 345 Gene3D G3DSA:3.40.710.10 5 334 3.1E-58 T 01-11-2018 MLA2C4_17945 9d981f95a44490d550c1a96116436a51 345 SUPERFAMILY SSF56601 7 326 1.42E-60 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_17945 9d981f95a44490d550c1a96116436a51 345 Pfam PF00144 Beta-lactamase 7 327 2.8E-38 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_19310 6a86e220bd15fbb57e4fded6143a3b26 379 Pfam PF13439 Glycosyltransferase Family 4 20 183 1.7E-12 T 01-11-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MLA2C4_19310 6a86e220bd15fbb57e4fded6143a3b26 379 SUPERFAMILY SSF53756 9 312 1.39E-54 T 01-11-2018 MLA2C4_19310 6a86e220bd15fbb57e4fded6143a3b26 379 Gene3D G3DSA:3.40.50.2000 180 312 6.1E-54 T 01-11-2018 MLA2C4_19310 6a86e220bd15fbb57e4fded6143a3b26 379 Gene3D G3DSA:3.40.50.2000 20 179 6.1E-54 T 01-11-2018 MLA2C4_19310 6a86e220bd15fbb57e4fded6143a3b26 379 Pfam PF00534 Glycosyl transferases group 1 196 315 1.7E-25 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_17105 901fc02d8bbe1f39c6644f8452d16dc5 415 Pfam PF06245 Protein of unknown function (DUF1015) 4 412 5.2E-141 T 01-11-2018 IPR008323 Uncharacterised conserved protein UCP033563 MLA2C4_17105 901fc02d8bbe1f39c6644f8452d16dc5 415 PIRSF PIRSF033563 1 415 4.7E-162 T 01-11-2018 IPR008323 Uncharacterised conserved protein UCP033563 MLA2C4_15770 248318a7d013e627879f305a76d10a38 115 Gene3D G3DSA:3.10.180.10 8 115 6.5E-16 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15770 248318a7d013e627879f305a76d10a38 115 SUPERFAMILY SSF54593 6 114 1.97E-17 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_10310 6e0311277a37b5ad8e22ca4f0db3ad1a 219 SUPERFAMILY SSF51735 1 210 5.64E-42 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_10310 6e0311277a37b5ad8e22ca4f0db3ad1a 219 Pfam PF13460 NAD(P)H-binding 10 125 3.8E-11 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_10310 6e0311277a37b5ad8e22ca4f0db3ad1a 219 Gene3D G3DSA:3.40.50.720 1 219 1.8E-59 T 01-11-2018 MLA2C4_15440 1ac91c8c00b55dd352221cf6df1ef50c 251 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_15440 1ac91c8c00b55dd352221cf6df1ef50c 251 SMART SM00382 31 208 2.4E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_15440 1ac91c8c00b55dd352221cf6df1ef50c 251 Pfam PF00005 ABC transporter 22 158 6.3E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_15440 1ac91c8c00b55dd352221cf6df1ef50c 251 Gene3D G3DSA:3.40.50.300 3 243 7.8E-64 T 01-11-2018 MLA2C4_15440 1ac91c8c00b55dd352221cf6df1ef50c 251 SUPERFAMILY SSF52540 3 231 1.33E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 222 3.2E-49 T 01-11-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 SUPERFAMILY SSF53681 2 113 3.27E-27 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 Gene3D G3DSA:3.40.50.1860 103 213 4.0E-74 T 01-11-2018 MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 Gene3D G3DSA:3.40.50.1860 5 221 4.0E-74 T 01-11-2018 MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 191 201 - T 01-11-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 226 2.8E-64 T 01-11-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 MLA2C4_14090 7595c1adc7d9981a4f1a988da5d838b2 227 SUPERFAMILY SSF53681 117 226 1.8E-32 T 01-11-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MLA2C4_21085 6bb5ccd1f2820e2b2551004dcb2896de 45 Pfam PF12841 YvrJ protein family 7 41 5.4E-18 T 01-11-2018 IPR024419 Protein of unknown function YvrJ MLA2C4_10620 ff3697da1601a2f1a6ad7b707721a740 186 SUPERFAMILY SSF55144 2 160 1.31E-13 T 01-11-2018 IPR009097 Cyclic phosphodiesterase MLA2C4_10620 ff3697da1601a2f1a6ad7b707721a740 186 Pfam PF13563 2'-5' RNA ligase superfamily 32 161 1.1E-11 T 01-11-2018 MLA2C4_10620 ff3697da1601a2f1a6ad7b707721a740 186 Gene3D G3DSA:3.90.1140.10 2 181 2.2E-16 T 01-11-2018 MLA2C4_16065 c300eb3511ef2a8d52822d9ee092d1c9 180 Pfam PF04229 GrpB protein 18 180 4.9E-44 T 01-11-2018 IPR007344 GrpB/Dephospho-CoA kinase MLA2C4_16065 c300eb3511ef2a8d52822d9ee092d1c9 180 Gene3D G3DSA:3.30.460.10 14 180 1.2E-46 T 01-11-2018 MLA2C4_16065 c300eb3511ef2a8d52822d9ee092d1c9 180 SUPERFAMILY SSF81301 20 180 5.23E-40 T 01-11-2018 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 Pfam PF01381 Helix-turn-helix 15 62 1.0E-9 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SUPERFAMILY SSF48452 119 264 2.94E-6 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SMART SM00530 11 65 2.3E-8 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 Gene3D G3DSA:1.25.40.10 167 419 3.1E-53 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SUPERFAMILY SSF47413 7 65 8.16E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 Gene3D G3DSA:1.25.40.1000 65 166 7.3E-56 T 01-11-2018 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 Pfam PF13424 Tetratricopeptide repeat 234 301 1.4E-7 T 01-11-2018 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 Gene3D G3DSA:1.10.260.40 4 64 1.3E-12 T 01-11-2018 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SUPERFAMILY SSF48452 233 416 1.82E-14 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SMART SM00028 151 184 85.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SMART SM00028 270 303 0.0029 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SMART SM00028 308 341 30.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_03165 e935152bc68ab057a4734738a61afab9 419 SMART SM00028 229 262 24.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.1E-19 T 01-11-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 5.1E-19 T 01-11-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 5.1E-19 T 01-11-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 Pfam PF01197 Ribosomal protein L31 1 79 2.8E-28 T 01-11-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 Gene3D G3DSA:2.30.170.50 1 81 1.2E-25 T 01-11-2018 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 01-11-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 1.5E-19 T 01-11-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.385 T 01-11-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_27600 5b79b96b54b1abb543ca3497470dbd64 81 SUPERFAMILY SSF143800 1 80 1.18E-23 T 01-11-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 SUPERFAMILY SSF46689 58 115 1.03E-15 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 SUPERFAMILY SSF46689 7 56 6.4E-10 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 Pfam PF14526 Integron-associated effector binding protein 136 297 4.4E-30 T 01-11-2018 IPR029441 Integron-associated effector binding protein MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 Gene3D G3DSA:1.10.10.60 59 113 1.9E-20 T 01-11-2018 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 Gene3D G3DSA:3.20.80.10 133 300 2.2E-44 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 89 105 7.2E-7 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 74 89 7.2E-7 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 Gene3D G3DSA:1.10.10.60 1 58 4.4E-14 T 01-11-2018 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 SMART SM00871 133 298 4.5E-38 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 SUPERFAMILY SSF55136 133 300 1.1E-29 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 Pfam PF12833 Helix-turn-helix domain 28 107 2.1E-25 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_05870 aae914b43a0f43f67d0ae5922472dc2c 300 SMART SM00342 22 105 4.1E-31 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 01-11-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 Gene3D G3DSA:2.160.10.10 1 185 2.6E-73 T 01-11-2018 MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 SMART SM01266 5 59 5.3E-20 T 01-11-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 SUPERFAMILY SSF51161 1 184 6.52E-57 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 Pfam PF12464 Maltose acetyltransferase 7 58 2.8E-14 T 01-11-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 93 110 0.18 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_24220 46d8c8d37cedbb77179120b74d9e10df 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 130 165 6.8E-12 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_27150 633e9a5c2810da2580c6c3947b767047 132 Pfam PF14271 Domain of unknown function (DUF4359) 16 119 3.5E-17 T 01-11-2018 IPR025578 Protein of unknown function DUF4359 MLA2C4_24675 1b8834c12302046db44cad86032a3897 253 Gene3D G3DSA:3.40.50.300 3 251 6.8E-67 T 01-11-2018 MLA2C4_24675 1b8834c12302046db44cad86032a3897 253 SMART SM00382 35 234 1.9E-11 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_24675 1b8834c12302046db44cad86032a3897 253 SUPERFAMILY SSF52540 6 227 5.78E-67 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_24675 1b8834c12302046db44cad86032a3897 253 Pfam PF00005 ABC transporter 26 174 2.6E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03620 e10376f4ef1784c4283de4bdd2af1dac 210 Pfam PF04203 Sortase family 83 203 2.3E-28 T 01-11-2018 IPR005754 Sortase family MLA2C4_03620 e10376f4ef1784c4283de4bdd2af1dac 210 Gene3D G3DSA:2.40.260.10 53 210 1.4E-46 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_03620 e10376f4ef1784c4283de4bdd2af1dac 210 SUPERFAMILY SSF63817 12 205 2.35E-44 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_03620 e10376f4ef1784c4283de4bdd2af1dac 210 TIGRFAM TIGR01076 sortase_fam: sortase 81 202 6.9E-25 T 01-11-2018 IPR005754 Sortase family MLA2C4_09375 940b2eb5c5b6dbaaa8540331b2c84302 445 Pfam PF00209 Sodium:neurotransmitter symporter family 4 122 3.2E-23 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_09375 940b2eb5c5b6dbaaa8540331b2c84302 445 Pfam PF00209 Sodium:neurotransmitter symporter family 148 440 9.9E-29 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_09375 940b2eb5c5b6dbaaa8540331b2c84302 445 SUPERFAMILY SSF161070 5 442 1.31E-131 T 01-11-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MLA2C4_09375 940b2eb5c5b6dbaaa8540331b2c84302 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 8.4E-12 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_09375 940b2eb5c5b6dbaaa8540331b2c84302 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 8.4E-12 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_09375 940b2eb5c5b6dbaaa8540331b2c84302 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 8.4E-12 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_13605 88d09941cc7bf4c3d2db95c144e00dfb 113 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 7.3E-18 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_13605 88d09941cc7bf4c3d2db95c144e00dfb 113 SUPERFAMILY SSF46785 11 104 5.45E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_13605 88d09941cc7bf4c3d2db95c144e00dfb 113 Gene3D G3DSA:1.10.10.10 2 110 5.5E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.213 T 01-11-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 01-11-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 9.7E-65 T 01-11-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 PIRSF PIRSF002181 1 143 2.8E-50 T 01-11-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 Gene3D G3DSA:3.90.1180.10 1 143 6.5E-61 T 01-11-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 Pfam PF00572 Ribosomal protein L13 15 139 1.0E-56 T 01-11-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00840 ca887ba7c53142f3967062ae7d0af2e1 145 SUPERFAMILY SSF52161 5 143 1.11E-59 T 01-11-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_27805 2f452b3e716e4e2df8df92275b147bb2 387 Gene3D G3DSA:1.20.1250.20 3 373 2.4E-63 T 01-11-2018 MLA2C4_27805 2f452b3e716e4e2df8df92275b147bb2 387 SUPERFAMILY SSF103473 1 378 1.29E-65 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_27805 2f452b3e716e4e2df8df92275b147bb2 387 Pfam PF07690 Major Facilitator Superfamily 13 341 3.4E-43 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_27805 2f452b3e716e4e2df8df92275b147bb2 387 PRINTS PR01035 Tetracycline resistance protein signature 159 179 8.6E-16 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_27805 2f452b3e716e4e2df8df92275b147bb2 387 PRINTS PR01035 Tetracycline resistance protein signature 18 34 8.6E-16 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_27805 2f452b3e716e4e2df8df92275b147bb2 387 PRINTS PR01035 Tetracycline resistance protein signature 131 153 8.6E-16 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_18155 38c2f7cff4bab48239f4c9590881b833 377 SUPERFAMILY SSF56601 56 361 3.81E-78 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_18155 38c2f7cff4bab48239f4c9590881b833 377 Pfam PF00144 Beta-lactamase 76 357 5.2E-57 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_18155 38c2f7cff4bab48239f4c9590881b833 377 Gene3D G3DSA:3.40.710.10 61 365 9.6E-80 T 01-11-2018 MLA2C4_27845 60bcd00aad33f602626cf73908e87c1f 314 Gene3D G3DSA:3.40.50.1980 164 314 1.9E-33 T 01-11-2018 MLA2C4_27845 60bcd00aad33f602626cf73908e87c1f 314 Gene3D G3DSA:3.40.50.1980 38 163 6.3E-31 T 01-11-2018 MLA2C4_27845 60bcd00aad33f602626cf73908e87c1f 314 SUPERFAMILY SSF53807 41 307 7.06E-56 T 01-11-2018 MLA2C4_27845 60bcd00aad33f602626cf73908e87c1f 314 Pfam PF01497 Periplasmic binding protein 92 288 2.9E-32 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_26820 33b06c6308a7a99a4c52780a6ad646d2 228 SMART SM00382 27 221 9.5E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_26820 33b06c6308a7a99a4c52780a6ad646d2 228 Gene3D G3DSA:3.40.50.300 1 221 1.2E-65 T 01-11-2018 MLA2C4_26820 33b06c6308a7a99a4c52780a6ad646d2 228 Pfam PF00005 ABC transporter 20 165 1.4E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26820 33b06c6308a7a99a4c52780a6ad646d2 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 7.5E-88 T 01-11-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 MLA2C4_26820 33b06c6308a7a99a4c52780a6ad646d2 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26820 33b06c6308a7a99a4c52780a6ad646d2 228 SUPERFAMILY SSF52540 1 218 1.86E-69 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15165 e5f76537cbda462ffbc62b8df25f985f 332 Gene3D G3DSA:3.30.200.20 6 113 2.6E-9 T 01-11-2018 MLA2C4_15165 e5f76537cbda462ffbc62b8df25f985f 332 Gene3D G3DSA:3.90.1200.10 120 296 1.5E-20 T 01-11-2018 MLA2C4_15165 e5f76537cbda462ffbc62b8df25f985f 332 SUPERFAMILY SSF56112 16 307 1.83E-44 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_15165 e5f76537cbda462ffbc62b8df25f985f 332 Pfam PF01636 Phosphotransferase enzyme family 32 267 2.6E-21 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 Gene3D G3DSA:3.30.1440.10 1 179 1.0E-83 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 SUPERFAMILY SSF55282 3 178 6.12E-78 T 01-11-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.015 T 01-11-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.0E-42 T 01-11-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 PIRSF PIRSF002161 1 179 1.9E-69 T 01-11-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 Pfam PF00281 Ribosomal protein L5 24 80 2.0E-28 T 01-11-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00735 b00cbd747107e84b39e53669dd31a287 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 01-11-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_16095 4475ca23a4f5dde3d6164af57c8f69ea 149 Pfam PF13302 Acetyltransferase (GNAT) domain 43 134 1.1E-22 T 01-11-2018 IPR000182 GNAT domain MLA2C4_16095 4475ca23a4f5dde3d6164af57c8f69ea 149 SUPERFAMILY SSF55729 3 136 7.34E-27 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_16095 4475ca23a4f5dde3d6164af57c8f69ea 149 Gene3D G3DSA:3.40.630.30 2 145 5.3E-31 T 01-11-2018 MLA2C4_23060 2cdedc5d941083317d755fc98a8464ba 176 Pfam PF08977 Bypass of Forespore C, N terminal 39 89 4.7E-21 T 01-11-2018 IPR015071 Bypass-of-forespore C, N-terminal MLA2C4_23060 2cdedc5d941083317d755fc98a8464ba 176 Gene3D G3DSA:3.30.70.1740 91 167 6.7E-29 T 01-11-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily MLA2C4_23060 2cdedc5d941083317d755fc98a8464ba 176 Pfam PF08955 BofC C-terminal domain 91 163 2.3E-24 T 01-11-2018 IPR015050 Bypass of forespore C, C-terminal MLA2C4_23060 2cdedc5d941083317d755fc98a8464ba 176 Gene3D G3DSA:3.10.20.420 37 90 1.6E-15 T 01-11-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily MLA2C4_14815 b0ea7234a5a37052a76e3592ee8b990f 128 Pfam PF10990 Protein of unknown function (DUF2809) 32 115 1.9E-30 T 01-11-2018 IPR021257 Protein of unknown function DUF2809 MLA2C4_10585 4684f6e7466ebf84f1b0cc6eda1d180a 402 Gene3D G3DSA:3.40.50.2000 216 379 8.4E-126 T 01-11-2018 MLA2C4_10585 4684f6e7466ebf84f1b0cc6eda1d180a 402 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 231 371 9.7E-26 T 01-11-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 MLA2C4_10585 4684f6e7466ebf84f1b0cc6eda1d180a 402 SUPERFAMILY SSF53756 1 391 1.8E-78 T 01-11-2018 MLA2C4_10585 4684f6e7466ebf84f1b0cc6eda1d180a 402 Gene3D G3DSA:3.40.50.2000 5 390 8.4E-126 T 01-11-2018 MLA2C4_10585 4684f6e7466ebf84f1b0cc6eda1d180a 402 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 7 394 1.3E-118 T 01-11-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 MLA2C4_23780 96e187d5a1ddc9a066e6154cb8fd4be6 293 PIRSF PIRSF012563 12 285 5.8E-114 T 01-11-2018 IPR014199 Sporulation protein YtxC MLA2C4_23780 96e187d5a1ddc9a066e6154cb8fd4be6 293 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 2 267 2.0E-87 T 01-11-2018 IPR014199 Sporulation protein YtxC MLA2C4_23780 96e187d5a1ddc9a066e6154cb8fd4be6 293 Pfam PF08812 YtxC-like family 55 267 1.0E-54 T 01-11-2018 IPR014199 Sporulation protein YtxC MLA2C4_09475 e375d854a62197f3874dab86cfeb9549 367 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 57 296 4.7E-70 T 01-11-2018 IPR019079 Capsule synthesis protein, CapA MLA2C4_09475 e375d854a62197f3874dab86cfeb9549 367 SUPERFAMILY SSF56300 56 337 1.09E-44 T 01-11-2018 MLA2C4_09475 e375d854a62197f3874dab86cfeb9549 367 Gene3D G3DSA:3.60.21.10 110 353 1.1E-14 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_09475 e375d854a62197f3874dab86cfeb9549 367 SMART SM00854 57 297 2.3E-85 T 01-11-2018 IPR019079 Capsule synthesis protein, CapA MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 01-11-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 8.2E-21 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 8.2E-21 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 8.2E-21 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 SUPERFAMILY SSF51306 27 180 6.49E-53 T 01-11-2018 IPR036286 LexA/Signal peptidase-like superfamily MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 Gene3D G3DSA:2.10.109.10 59 187 1.3E-51 T 01-11-2018 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 Pfam PF00717 Peptidase S24-like 36 103 4.0E-22 T 01-11-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 01-11-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 01-11-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MLA2C4_05985 0145021ed0b0642f6aad642b0c9f0556 187 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 3.9E-55 T 01-11-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 SMART SM00644 163 298 2.2E-25 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 175 297 1.4E-23 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 Gene3D G3DSA:3.40.80.10 167 335 1.6E-46 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 Pfam PF00395 S-layer homology domain 473 516 1.1E-9 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 Pfam PF00395 S-layer homology domain 546 579 3.6E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 Pfam PF00395 S-layer homology domain 419 458 3.9E-9 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 Gene3D G3DSA:2.30.30.40 340 406 1.9E-8 T 01-11-2018 MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 SMART SM00287 345 404 0.0052 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_17180 69f547403d23b9e40c2ea943b1826d68 591 SUPERFAMILY SSF55846 156 316 2.75E-45 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_14840 7c7133d5e37561c702dd3d13b2508310 268 Pfam PF01183 Glycosyl hydrolases family 25 5 168 1.1E-25 T 01-11-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 MLA2C4_14840 7c7133d5e37561c702dd3d13b2508310 268 Gene3D G3DSA:3.30.70.2030 189 268 5.3E-41 T 01-11-2018 MLA2C4_14840 7c7133d5e37561c702dd3d13b2508310 268 Gene3D G3DSA:3.20.20.80 2 188 3.5E-74 T 01-11-2018 MLA2C4_14840 7c7133d5e37561c702dd3d13b2508310 268 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 225 267 3.5E-23 T 01-11-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase MetaCyc: PWY-7883 MLA2C4_14840 7c7133d5e37561c702dd3d13b2508310 268 SUPERFAMILY SSF51445 4 186 2.16E-45 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Gene3D G3DSA:3.40.50.620 109 443 2.8E-123 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 84 8.6E-16 T 01-11-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 562 25.481 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Pfam PF05746 DALR anticodon binding domain 450 562 8.8E-32 T 01-11-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 SUPERFAMILY SSF52374 112 444 2.0E-98 T 01-11-2018 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 5.4E-20 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 5.4E-20 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 5.4E-20 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 5.4E-20 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 SUPERFAMILY SSF55190 2 105 3.27E-24 T 01-11-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 SUPERFAMILY SSF47323 444 562 3.27E-33 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Gene3D G3DSA:3.30.1360.70 2 105 2.9E-28 T 01-11-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Pfam PF00750 tRNA synthetases class I (R) 95 435 2.0E-99 T 01-11-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 SMART SM00836 450 562 4.0E-40 T 01-11-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 4 562 1.5E-153 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 SMART SM01016 5 84 4.2E-20 T 01-11-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_10985 8954254bc79f259d6aea8c5f7c2ac692 562 Gene3D G3DSA:1.10.730.10 444 562 5.4E-35 T 01-11-2018 MLA2C4_25055 5329feff3e99342b129c2622733811f3 206 SUPERFAMILY SSF63817 24 201 1.83E-34 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_25055 5329feff3e99342b129c2622733811f3 206 TIGRFAM TIGR01076 sortase_fam: sortase 77 199 4.3E-23 T 01-11-2018 IPR005754 Sortase family MLA2C4_25055 5329feff3e99342b129c2622733811f3 206 Gene3D G3DSA:2.40.260.10 61 206 4.0E-44 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_25055 5329feff3e99342b129c2622733811f3 206 Pfam PF04203 Sortase family 78 200 1.4E-26 T 01-11-2018 IPR005754 Sortase family MLA2C4_04805 fb72961e42aa91baaa41f8b81b5791cb 396 Pfam PF14286 DHHW protein 114 352 5.2E-16 T 01-11-2018 IPR025945 DHHW protein MLA2C4_25910 e6df7d7f260e5a7ff575c7dea9d2eb33 143 SUPERFAMILY SSF82649 2 141 1.39E-51 T 01-11-2018 MLA2C4_25910 e6df7d7f260e5a7ff575c7dea9d2eb33 143 Pfam PF01592 NifU-like N terminal domain 10 127 8.9E-37 T 01-11-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MLA2C4_25910 e6df7d7f260e5a7ff575c7dea9d2eb33 143 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 139 7.2E-56 T 01-11-2018 MLA2C4_25910 e6df7d7f260e5a7ff575c7dea9d2eb33 143 Gene3D G3DSA:3.90.1010.10 2 143 2.4E-60 T 01-11-2018 MLA2C4_06755 6087955f2da11776a46bf73d7f3c3d6a 571 Pfam PF09369 Domain of unknown function (DUF1998) 437 533 2.0E-7 T 01-11-2018 IPR018973 DEAD/DEAH-box helicase, putative MLA2C4_11505 fc2144f1296fa4a0d597173776df542d 71 PIRSF PIRSF037262 1 71 1.3E-30 T 01-11-2018 IPR010673 Protein of unknown function UPF0346 MLA2C4_11505 fc2144f1296fa4a0d597173776df542d 71 Hamap MF_01538 UPF0346 protein . 1 70 23.177 T 01-11-2018 IPR010673 Protein of unknown function UPF0346 MLA2C4_11505 fc2144f1296fa4a0d597173776df542d 71 Gene3D G3DSA:1.10.150.260 2 71 7.3E-24 T 01-11-2018 IPR036806 YozE SAM-like superfamily MLA2C4_11505 fc2144f1296fa4a0d597173776df542d 71 Pfam PF06855 YozE SAM-like fold 4 69 1.0E-23 T 01-11-2018 IPR023089 YozE SAM-like domain MLA2C4_11505 fc2144f1296fa4a0d597173776df542d 71 SUPERFAMILY SSF140652 2 70 3.66E-25 T 01-11-2018 IPR036806 YozE SAM-like superfamily MLA2C4_05370 1d26798ef3beccdec55c792e163ca904 376 Pfam PF07282 Putative transposase DNA-binding domain 300 372 1.2E-17 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_05370 1d26798ef3beccdec55c792e163ca904 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 251 324 4.4E-7 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_05370 1d26798ef3beccdec55c792e163ca904 376 Pfam PF12323 Helix-turn-helix domain 1 45 1.1E-11 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_05370 1d26798ef3beccdec55c792e163ca904 376 Pfam PF01385 Probable transposase 172 283 8.1E-13 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_24885 e6d66885984795f93ddfdb59babc11a3 268 Gene3D G3DSA:1.10.3720.10 66 261 1.1E-23 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_24885 e6d66885984795f93ddfdb59babc11a3 268 SUPERFAMILY SSF161098 68 249 2.09E-29 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_24885 e6d66885984795f93ddfdb59babc11a3 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 259 2.0E-25 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_16285 99239ddc7ab11ec9d58a6a48f2d0b09e 170 Gene3D G3DSA:3.40.630.30 2 169 5.1E-42 T 01-11-2018 MLA2C4_16285 99239ddc7ab11ec9d58a6a48f2d0b09e 170 SUPERFAMILY SSF55729 8 159 3.71E-24 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_16285 99239ddc7ab11ec9d58a6a48f2d0b09e 170 Pfam PF00583 Acetyltransferase (GNAT) family 53 153 1.5E-10 T 01-11-2018 IPR000182 GNAT domain MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 Gene3D G3DSA:3.40.50.300 210 412 5.4E-52 T 01-11-2018 MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 SUPERFAMILY SSF52540 73 360 3.9E-73 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 Pfam PF00270 DEAD/DEAH box helicase 29 196 7.5E-51 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 SMART SM00490 258 339 2.7E-34 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 SMART SM00487 24 222 9.5E-62 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 Pfam PF00271 Helicase conserved C-terminal domain 241 339 8.4E-30 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_13200 7218e4ed8c268f46b30a680c75b69f55 446 Gene3D G3DSA:3.40.50.300 5 209 9.9E-75 T 01-11-2018 MLA2C4_15390 7179a065e698f24048ba8d9d006f23b1 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 1.4E-20 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_15390 7179a065e698f24048ba8d9d006f23b1 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 3.7E-17 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_23875 e0d67d68c94b0799358ade0ad6cd7c47 153 Pfam PF04284 Protein of unknown function (DUF441) 7 146 2.1E-48 T 01-11-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame MLA2C4_23875 e0d67d68c94b0799358ade0ad6cd7c47 153 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 6.0E-44 T 01-11-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame MLA2C4_23875 e0d67d68c94b0799358ade0ad6cd7c47 153 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 19.171 T 01-11-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame MLA2C4_25815 04f5ff109e629163b060146a881ac4a7 146 Pfam PF01934 Protein of unknown function DUF86 12 126 5.4E-22 T 01-11-2018 IPR008201 Protein of unknown function DUF86 MLA2C4_25815 04f5ff109e629163b060146a881ac4a7 146 Gene3D G3DSA:1.20.120.580 1 144 8.1E-54 T 01-11-2018 IPR037038 Bsu32300-like superfamily MLA2C4_05855 8531f1a4551742adddea504bf694af5d 372 Pfam PF13791 Sigma factor regulator C-terminal 205 362 4.9E-42 T 01-11-2018 IPR025672 Sigma factor regulator C-terminal domain MLA2C4_05855 8531f1a4551742adddea504bf694af5d 372 Pfam PF13800 Sigma factor regulator N-terminal 65 151 4.0E-16 T 01-11-2018 IPR029101 Sigma factor regulator, N-terminal MLA2C4_05855 8531f1a4551742adddea504bf694af5d 372 Pfam PF13490 Putative zinc-finger 3 36 4.0E-6 T 01-11-2018 IPR027383 Putative zinc-finger MLA2C4_28245 9cfeb1631ae93f5a79d923b32e250107 610 SUPERFAMILY SSF52317 99 231 4.12E-7 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_28245 9cfeb1631ae93f5a79d923b32e250107 610 Gene3D G3DSA:3.20.20.370 261 441 1.2E-5 T 01-11-2018 MLA2C4_28245 9cfeb1631ae93f5a79d923b32e250107 610 SUPERFAMILY SSF88713 283 420 2.45E-6 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_28245 9cfeb1631ae93f5a79d923b32e250107 610 Pfam PF09960 Uncharacterised protein conserved in bacteria (DUF2194) 67 594 1.5E-100 T 01-11-2018 IPR018695 Protein of unknown function DUF2194 MLA2C4_06375 cfa38cf1751baca646f63f4a16982074 245 Gene3D G3DSA:3.90.550.10 1 245 7.9E-75 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_06375 cfa38cf1751baca646f63f4a16982074 245 Pfam PF00483 Nucleotidyl transferase 2 231 7.4E-53 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_06375 cfa38cf1751baca646f63f4a16982074 245 SUPERFAMILY SSF53448 2 235 2.71E-68 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 Gene3D G3DSA:3.20.20.80 145 316 9.4E-33 T 01-11-2018 MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 Gene3D G3DSA:3.20.20.80 29 144 1.0E-39 T 01-11-2018 MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 SUPERFAMILY SSF51011 321 402 1.44E-11 T 01-11-2018 MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 SUPERFAMILY SSF51445 32 321 1.83E-52 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 Pfam PF00128 Alpha amylase, catalytic domain 191 285 2.9E-10 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 Pfam PF00128 Alpha amylase, catalytic domain 70 138 2.9E-23 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 Gene3D G3DSA:2.60.40.1180 317 411 5.5E-35 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_06090 bfdaa93cdff2954daeba928d975b989d 433 SMART SM00642 42 312 6.0E-14 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_24125 4fadbe33d0519bfecb32d0b8aa53b485 522 Gene3D G3DSA:2.30.40.10 7 494 1.4E-128 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_24125 4fadbe33d0519bfecb32d0b8aa53b485 522 SUPERFAMILY SSF51338 4 520 8.64E-16 T 01-11-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MLA2C4_24125 4fadbe33d0519bfecb32d0b8aa53b485 522 Pfam PF07969 Amidohydrolase family 49 518 2.7E-131 T 01-11-2018 IPR013108 Amidohydrolase 3 MLA2C4_24125 4fadbe33d0519bfecb32d0b8aa53b485 522 Gene3D G3DSA:3.10.310.70 77 194 1.4E-128 T 01-11-2018 MLA2C4_24125 4fadbe33d0519bfecb32d0b8aa53b485 522 SUPERFAMILY SSF51556 58 477 2.01E-33 T 01-11-2018 IPR032466 Metal-dependent hydrolase MLA2C4_24125 4fadbe33d0519bfecb32d0b8aa53b485 522 Gene3D G3DSA:3.20.20.140 59 477 1.4E-128 T 01-11-2018 MLA2C4_01650 8c50ce70b60f56a81c204915a3ddf472 144 Pfam PF14307 Glycosyltransferase WbsX 46 125 2.6E-27 T 01-11-2018 IPR032719 Glycosyltransferase WbsX MLA2C4_12290 938475f0e9958b0c8d017b7d080c9202 343 SUPERFAMILY SSF53474 57 339 2.92E-35 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12290 938475f0e9958b0c8d017b7d080c9202 343 Pfam PF00561 alpha/beta hydrolase fold 63 173 7.5E-16 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12290 938475f0e9958b0c8d017b7d080c9202 343 Gene3D G3DSA:3.40.50.1820 40 342 7.2E-40 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12290 938475f0e9958b0c8d017b7d080c9202 343 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 93 104 1.3E-6 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_12290 938475f0e9958b0c8d017b7d080c9202 343 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 65 73 1.3E-6 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_12290 938475f0e9958b0c8d017b7d080c9202 343 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 141 155 1.3E-6 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_10200 c14265c7562f767782b83ef578404850 391 SUPERFAMILY SSF103473 2 380 2.35E-68 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_10200 c14265c7562f767782b83ef578404850 391 PRINTS PR01035 Tetracycline resistance protein signature 324 347 6.8E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10200 c14265c7562f767782b83ef578404850 391 PRINTS PR01035 Tetracycline resistance protein signature 157 177 6.8E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10200 c14265c7562f767782b83ef578404850 391 PRINTS PR01035 Tetracycline resistance protein signature 14 30 6.8E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10200 c14265c7562f767782b83ef578404850 391 PRINTS PR01035 Tetracycline resistance protein signature 129 151 6.8E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_10200 c14265c7562f767782b83ef578404850 391 Gene3D G3DSA:1.20.1250.20 1 379 8.9E-61 T 01-11-2018 MLA2C4_10200 c14265c7562f767782b83ef578404850 391 Pfam PF07690 Major Facilitator Superfamily 9 314 4.1E-38 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_12515 39f4d8cf762558534d7f449e096cd3f9 294 Pfam PF13527 Acetyltransferase (GNAT) domain 16 132 1.8E-18 T 01-11-2018 MLA2C4_12515 39f4d8cf762558534d7f449e096cd3f9 294 SUPERFAMILY SSF55729 13 276 1.18E-35 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12515 39f4d8cf762558534d7f449e096cd3f9 294 Gene3D G3DSA:3.40.630.30 3 166 5.6E-23 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:2.60.40.3600 662 733 1.3E-22 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:2.60.40.3600 864 935 1.0E-22 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:2.60.40.3600 456 532 3.8E-33 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:2.60.40.3600 1065 1139 3.3E-20 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Pfam PF03272 Putative mucin or carbohydrate-binding module 1145 1264 1.8E-24 T 01-11-2018 IPR004954 Putative mucin/carbohydrate-binding domain MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Pfam PF03272 Putative mucin or carbohydrate-binding module 538 656 5.8E-29 T 01-11-2018 IPR004954 Putative mucin/carbohydrate-binding domain MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Pfam PF03272 Putative mucin or carbohydrate-binding module 951 1062 2.2E-20 T 01-11-2018 IPR004954 Putative mucin/carbohydrate-binding domain MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Pfam PF03272 Putative mucin or carbohydrate-binding module 739 858 3.1E-24 T 01-11-2018 IPR004954 Putative mucin/carbohydrate-binding domain MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:1.10.1740.210 161 297 6.3E-45 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 155 416 4.6E-66 T 01-11-2018 IPR031161 Peptidase family M60 domain MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 SMART SM01276 78 366 1.7E-103 T 01-11-2018 IPR031161 Peptidase family M60 domain MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:1.10.390.30 298 455 1.4E-55 T 01-11-2018 MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Pfam PF17291 N-terminal domain of M60-like peptidases 66 152 7.8E-14 T 01-11-2018 IPR035423 M60-like domain, N-terminal MLA2C4_26350 fc700d2dec9adcc1e1966a4732d048be 1268 Gene3D G3DSA:2.60.120.1250 40 160 6.3E-44 T 01-11-2018 MLA2C4_18890 943d4b0bff582ad69f25fb7a9b917c68 70 Pfam PF05532 CsbD-like 10 61 1.2E-18 T 01-11-2018 IPR008462 CsbD-like domain MLA2C4_18890 943d4b0bff582ad69f25fb7a9b917c68 70 SUPERFAMILY SSF69047 9 64 6.8E-13 T 01-11-2018 IPR036629 YjbJ superfamily MLA2C4_18890 943d4b0bff582ad69f25fb7a9b917c68 70 Gene3D G3DSA:1.10.1470.10 9 69 1.6E-8 T 01-11-2018 IPR036629 YjbJ superfamily MLA2C4_09960 d86ac51d9592d1e9cdcd46a170889a7a 243 Pfam PF12730 ABC-2 family transporter protein 5 179 1.6E-21 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 Pfam PF01926 50S ribosome-binding GTPase 200 325 8.7E-18 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 Gene3D G3DSA:3.40.50.11060 17 136 1.6E-41 T 01-11-2018 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 Pfam PF16360 GTP-binding GTPase Middle Region 112 192 3.0E-26 T 01-11-2018 IPR032305 GTP-binding protein, middle domain MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 Gene3D G3DSA:3.40.50.300 197 368 6.2E-36 T 01-11-2018 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 1.7E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 1.7E-6 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 7 361 8.6E-140 T 01-11-2018 IPR016496 GTPase HflX GO:0005525 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 SUPERFAMILY SSF52540 198 372 1.47E-34 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 Hamap MF_00900 GTPase HflX [hflX]. 25 391 47.071 T 01-11-2018 IPR016496 GTPase HflX GO:0005525 MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 Pfam PF13167 GTP-binding GTPase N-terminal 23 110 1.1E-34 T 01-11-2018 IPR025121 GTPase HflX, N-terminal MLA2C4_09340 62ab6089dd6b58d4845799506f1fbbdc 419 PIRSF PIRSF006809 1 418 1.4E-146 T 01-11-2018 IPR016496 GTPase HflX GO:0005525 MLA2C4_23195 bcbf39f96049a90c053457b93fe8c680 228 Gene3D G3DSA:3.30.160.540 7 87 4.2E-29 T 01-11-2018 MLA2C4_23195 bcbf39f96049a90c053457b93fe8c680 228 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 108 207 2.8E-31 T 01-11-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MLA2C4_23195 bcbf39f96049a90c053457b93fe8c680 228 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 210 2.6E-36 T 01-11-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MLA2C4_23195 bcbf39f96049a90c053457b93fe8c680 228 SUPERFAMILY SSF63848 106 207 2.62E-30 T 01-11-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 MLA2C4_23195 bcbf39f96049a90c053457b93fe8c680 228 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 211 21.77 T 01-11-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MLA2C4_23195 bcbf39f96049a90c053457b93fe8c680 228 Gene3D G3DSA:2.160.20.70 101 226 1.3E-37 T 01-11-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 2.6E-68 T 01-11-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 9.6E-59 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 9.6E-59 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 9.6E-59 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 9.6E-59 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 9.6E-59 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 9.6E-59 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 SUPERFAMILY SSF50249 2 137 1.37E-49 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 PIRSF PIRSF002133 1 137 4.4E-49 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.775 T 01-11-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 Pfam PF00164 Ribosomal protein S12/S23 32 136 1.8E-38 T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 01-11-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00645 f9858db140009cfbdfdc3d4864a3f9b3 140 Gene3D G3DSA:2.40.50.140 1 140 5.8E-63 T 01-11-2018 MLA2C4_05660 c9085d5c406895204a0d2d8bb09b7f13 483 Pfam PF03703 Bacterial PH domain 401 476 2.6E-10 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_05660 c9085d5c406895204a0d2d8bb09b7f13 483 Pfam PF03703 Bacterial PH domain 55 132 6.0E-16 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_05660 c9085d5c406895204a0d2d8bb09b7f13 483 Pfam PF03703 Bacterial PH domain 252 332 8.2E-10 T 01-11-2018 IPR005182 Domain of unknown function DUF304 MLA2C4_05660 c9085d5c406895204a0d2d8bb09b7f13 483 PIRSF PIRSF026631 1 483 6.8E-145 T 01-11-2018 IPR014529 Uncharacterised conserved protein UCP026631 MLA2C4_09760 439871836c52391bb0e524b22fa7213c 536 Pfam PF01425 Amidase 89 473 1.2E-71 T 01-11-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_09760 439871836c52391bb0e524b22fa7213c 536 Gene3D G3DSA:3.90.1300.10 24 536 2.1E-210 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_09760 439871836c52391bb0e524b22fa7213c 536 SUPERFAMILY SSF75304 67 532 2.09E-94 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_09670 8a77177fd268a0c58a2f242ee13efacb 189 Gene3D G3DSA:3.40.50.150 7 184 1.6E-25 T 01-11-2018 MLA2C4_09670 8a77177fd268a0c58a2f242ee13efacb 189 SUPERFAMILY SSF53335 40 167 2.66E-8 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_09670 8a77177fd268a0c58a2f242ee13efacb 189 Pfam PF13578 Methyltransferase domain 44 152 1.3E-16 T 01-11-2018 MLA2C4_27085 d2a7e6a149559785356c20c4deb4b9e5 433 SUPERFAMILY SSF53448 63 340 6.68E-54 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_27085 d2a7e6a149559785356c20c4deb4b9e5 433 Gene3D G3DSA:3.90.550.10 58 280 5.1E-45 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_27085 d2a7e6a149559785356c20c4deb4b9e5 433 Pfam PF13641 Glycosyltransferase like family 2 69 294 1.6E-33 T 01-11-2018 MLA2C4_25480 d23da90dfa824ba2a89e0d206185bb3d 226 PRINTS PR01837 MgtC/SapB protein signature 66 88 3.0E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_25480 d23da90dfa824ba2a89e0d206185bb3d 226 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.0E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_25480 d23da90dfa824ba2a89e0d206185bb3d 226 PRINTS PR01837 MgtC/SapB protein signature 94 118 3.0E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_25480 d23da90dfa824ba2a89e0d206185bb3d 226 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.0E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_25480 d23da90dfa824ba2a89e0d206185bb3d 226 Pfam PF02308 MgtC family 10 135 5.2E-33 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_07490 e5170b50ea7a64a0e0b784c7f80198af 628 PIRSF PIRSF005091 1 616 3.9E-175 T 01-11-2018 IPR012160 Lipoteichoic acid synthase-like MLA2C4_07490 e5170b50ea7a64a0e0b784c7f80198af 628 SUPERFAMILY SSF53649 242 613 3.93E-71 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_07490 e5170b50ea7a64a0e0b784c7f80198af 628 Pfam PF00884 Sulfatase 244 533 2.1E-37 T 01-11-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MLA2C4_07490 e5170b50ea7a64a0e0b784c7f80198af 628 Gene3D G3DSA:3.40.720.10 236 543 8.0E-77 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_20375 78da98b6f0811e28958357129e908040 87 Pfam PF02325 YGGT family 10 76 8.4E-23 T 01-11-2018 IPR003425 CCB3/YggT GO:0016020 MLA2C4_20935 be86591337239a392dbb8d5ad6e3eb11 129 Pfam PF11033 Competence protein J (ComJ) 2 126 1.6E-50 T 01-11-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ MLA2C4_20935 be86591337239a392dbb8d5ad6e3eb11 129 Gene3D G3DSA:2.60.34.30 1 124 1.3E-39 T 01-11-2018 IPR038691 DNA-entry nuclease inhibitor, ComJ superfamily MLA2C4_20935 be86591337239a392dbb8d5ad6e3eb11 129 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 3 105 4.0E-52 T 01-11-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 Pfam PF13602 Zinc-binding dehydrogenase 187 304 9.0E-25 T 01-11-2018 MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 1.0E-11 T 01-11-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 SUPERFAMILY SSF50129 1 149 5.02E-37 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 Gene3D G3DSA:3.40.50.720 128 254 6.8E-95 T 01-11-2018 MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 Gene3D G3DSA:3.90.180.10 8 304 6.8E-95 T 01-11-2018 MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 SUPERFAMILY SSF51735 117 240 3.95E-38 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_14535 4c40d6519692053d3078fc9e7a0db40a 308 SMART SM00829 10 305 3.1E-27 T 01-11-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MLA2C4_17905 8970e9f20d6b3370c7478890877004f2 106 SUPERFAMILY SSF46785 5 99 5.68E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17905 8970e9f20d6b3370c7478890877004f2 106 Pfam PF03551 Transcriptional regulator PadR-like family 16 87 1.5E-23 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_17905 8970e9f20d6b3370c7478890877004f2 106 Gene3D G3DSA:1.10.10.10 1 106 5.8E-40 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 SMART SM00646 396 515 4.5E-38 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 Pfam PF00395 S-layer homology domain 29 69 5.0E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 Pfam PF00395 S-layer homology domain 150 190 4.4E-6 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 Pfam PF00395 S-layer homology domain 87 129 6.3E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 SUPERFAMILY SSF53187 329 520 1.16E-48 T 01-11-2018 MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 331 515 4.1E-46 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_04855 39270b32a81ff131b21170f415ef4ce0 529 Gene3D G3DSA:3.40.630.40 327 524 1.7E-56 T 01-11-2018 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 Gene3D G3DSA:1.20.1250.20 1 203 1.4E-27 T 01-11-2018 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 Gene3D G3DSA:1.20.1250.20 204 389 2.1E-22 T 01-11-2018 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 131 152 3.1E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 279 302 3.1E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 3.1E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 44 62 3.1E-5 T 01-11-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 Pfam PF07690 Major Facilitator Superfamily 10 268 1.7E-27 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_24650 c298a2bf7af850f64a3427ff7597fae5 397 SUPERFAMILY SSF103473 3 386 1.83E-59 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 Gene3D G3DSA:3.30.420.40 153 316 3.6E-131 T 01-11-2018 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 Pfam PF06723 MreB/Mbl protein 9 334 7.2E-152 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 Gene3D G3DSA:3.90.640.10 185 258 3.6E-131 T 01-11-2018 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 Gene3D G3DSA:3.30.420.40 11 326 3.6E-131 T 01-11-2018 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 SUPERFAMILY SSF53067 8 146 3.11E-39 T 01-11-2018 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 SUPERFAMILY SSF53067 149 332 5.13E-51 T 01-11-2018 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 46 64 3.1E-60 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 66 89 3.1E-60 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 186 206 3.1E-60 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 299 325 3.1E-60 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 131 150 3.1E-60 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23210 f7ede945fc0f0f968a0ee9c28e2e3af4 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 335 9.2E-161 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_23440 e494fd27d13a539d99a85c375b5fd519 143 SUPERFAMILY SSF46785 3 137 4.85E-34 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_23440 e494fd27d13a539d99a85c375b5fd519 143 Pfam PF02082 Transcriptional regulator 1 81 6.7E-24 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_23440 e494fd27d13a539d99a85c375b5fd519 143 Gene3D G3DSA:1.10.10.10 1 143 1.9E-58 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_11560 c08833e2ee01404c63edebebd36b5a18 114 SUPERFAMILY SSF47413 1 69 3.38E-16 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_11560 c08833e2ee01404c63edebebd36b5a18 114 Gene3D G3DSA:1.10.260.40 4 112 4.9E-20 T 01-11-2018 MLA2C4_11560 c08833e2ee01404c63edebebd36b5a18 114 Pfam PF01381 Helix-turn-helix 8 62 1.8E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_11560 c08833e2ee01404c63edebebd36b5a18 114 SMART SM00530 7 62 1.8E-12 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_17275 dec8182b574e84ef65b10647f1fbd9d0 181 Pfam PF12840 Helix-turn-helix domain 6 64 1.6E-8 T 01-11-2018 MLA2C4_17275 dec8182b574e84ef65b10647f1fbd9d0 181 SUPERFAMILY SSF46785 6 146 1.59E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17275 dec8182b574e84ef65b10647f1fbd9d0 181 Gene3D G3DSA:1.20.1270.400 88 180 3.5E-8 T 01-11-2018 MLA2C4_17275 dec8182b574e84ef65b10647f1fbd9d0 181 Gene3D G3DSA:1.10.10.10 1 82 7.5E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27090 08897592992a43e8c7fc0e0a6f05361f 505 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 498 4.7E-161 T 01-11-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MLA2C4_27090 08897592992a43e8c7fc0e0a6f05361f 505 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 498 1.0E-191 T 01-11-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MLA2C4_27090 08897592992a43e8c7fc0e0a6f05361f 505 ProSitePatterns PS01303 BCCT family of transporters signature. 314 323 - T 01-11-2018 IPR018093 BCCT transporter, conserved site MLA2C4_27905 91cbeb1c337aa8f3639a2393fb846575 626 Pfam PF00589 Phage integrase family 373 486 3.1E-15 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_27905 91cbeb1c337aa8f3639a2393fb846575 626 Gene3D G3DSA:1.10.443.10 286 507 2.1E-20 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_27905 91cbeb1c337aa8f3639a2393fb846575 626 SUPERFAMILY SSF56349 155 492 7.36E-25 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_18440 60662872a8f48d7167ab7c202584d179 479 Gene3D G3DSA:1.20.1730.10 26 478 8.8E-80 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily MLA2C4_18440 60662872a8f48d7167ab7c202584d179 479 Pfam PF00474 Sodium:solute symporter family 39 434 1.3E-97 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_18440 60662872a8f48d7167ab7c202584d179 479 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 3 474 6.9E-240 T 01-11-2018 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0036376 MLA2C4_18440 60662872a8f48d7167ab7c202584d179 479 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 434 3.8E-89 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_18440 60662872a8f48d7167ab7c202584d179 479 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 158 183 - T 01-11-2018 IPR018212 Sodium/solute symporter, conserved site MLA2C4_22485 661b2f58b903e666a3b60359df1d39ba 319 Gene3D G3DSA:3.40.50.300 109 316 1.4E-75 T 01-11-2018 MLA2C4_22485 661b2f58b903e666a3b60359df1d39ba 319 Pfam PF02562 PhoH-like protein 113 316 3.1E-95 T 01-11-2018 IPR003714 PhoH-like protein GO:0005524 MLA2C4_22485 661b2f58b903e666a3b60359df1d39ba 319 SUPERFAMILY SSF52540 112 279 1.05E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 Gene3D G3DSA:1.10.10.10 1 92 3.2E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 Pfam PF00155 Aminotransferase class I and II 117 413 1.6E-13 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 SMART SM00345 19 78 3.9E-19 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 2.6E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 2.6E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 4.1E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 SUPERFAMILY SSF46785 9 86 4.02E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 SUPERFAMILY SSF53383 100 463 5.02E-77 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_10595 15dceea9c34e6d95d469cba802dea14c 466 Gene3D G3DSA:3.40.640.10 93 457 1.9E-116 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_18470 cf1594cc96ccd45d7c298a4313325b14 141 Pfam PF02681 Divergent PAP2 family 6 135 1.3E-49 T 01-11-2018 IPR003832 Protein of unknown function DUF212 MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 Gene3D G3DSA:3.40.50.1000 2 275 6.2E-84 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 01-11-2018 MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 278 2.2E-76 T 01-11-2018 MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 ProSitePatterns PS01229 Hypothetical cof family signature 2. 232 254 - T 01-11-2018 MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 251 2.3E-26 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 SUPERFAMILY SSF56784 2 282 1.71E-67 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 278 1.1E-56 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_14070 860561f654ce98bb154934da1c58d17d 283 Gene3D G3DSA:3.30.1240.10 80 207 6.2E-84 T 01-11-2018 MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 SUPERFAMILY SSF54373 268 326 2.35E-11 T 01-11-2018 MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 SUPERFAMILY SSF51905 3 386 2.29E-52 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 Pfam PF01266 FAD dependent oxidoreductase 5 365 9.5E-66 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 Gene3D G3DSA:3.50.50.60 6 369 2.5E-87 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 Gene3D G3DSA:3.30.9.10 85 326 2.5E-87 T 01-11-2018 MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 7.2E-8 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 319 325 7.2E-8 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_14995 723097419c5adf3f60d20eb10b436f53 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 7.2E-8 T 01-11-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MLA2C4_24545 f354e67a369c0297365c004e2fd863f4 139 Pfam PF13027 Protein of unknown function (DUF3888) 34 113 8.3E-15 T 01-11-2018 IPR024984 Protein of unknown function DUF3888 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 SUPERFAMILY SSF52777 188 417 4.89E-87 T 01-11-2018 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 SUPERFAMILY SSF51230 1 93 1.0E-24 T 01-11-2018 IPR011053 Single hybrid motif MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 Gene3D G3DSA:2.40.50.100 1 102 1.3E-25 T 01-11-2018 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 Pfam PF00364 Biotin-requiring enzyme 3 75 5.1E-20 T 01-11-2018 IPR000089 Biotin/lipoyl attachment MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 Gene3D G3DSA:4.10.320.10 125 163 5.2E-15 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 187 417 2.4E-80 T 01-11-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 01-11-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 2 418 2.1E-172 T 01-11-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 SUPERFAMILY SSF47005 119 162 9.02E-10 T 01-11-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 Pfam PF02817 e3 binding domain 125 159 5.0E-12 T 01-11-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MLA2C4_06590 ed029fa1bdff619f36c178333c0f032b 419 Gene3D G3DSA:3.30.559.10 187 418 6.0E-92 T 01-11-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MLA2C4_17760 91ed82d90b5d68936d0dbf7145f12658 137 Gene3D G3DSA:1.10.10.10 1 137 1.6E-40 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17760 91ed82d90b5d68936d0dbf7145f12658 137 SUPERFAMILY SSF46785 2 131 1.11E-27 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17760 91ed82d90b5d68936d0dbf7145f12658 137 Pfam PF02082 Transcriptional regulator 2 79 1.6E-20 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_25490 b28019b13dfb6eeea9c33cd7de9dc31b 137 SUPERFAMILY SSF160755 2 132 1.57E-37 T 01-11-2018 IPR036491 YugN-like superfamily MLA2C4_25490 b28019b13dfb6eeea9c33cd7de9dc31b 137 Gene3D G3DSA:3.30.310.100 4 106 1.7E-31 T 01-11-2018 IPR036491 YugN-like superfamily MLA2C4_25490 b28019b13dfb6eeea9c33cd7de9dc31b 137 Pfam PF08868 YugN-like family 3 132 1.3E-53 T 01-11-2018 IPR014967 Uncharacterised protein family, YugN-like MLA2C4_12340 2d7dfe72f278abd8e0b322625c65def4 313 SUPERFAMILY SSF53590 1 309 2.49E-83 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_12340 2d7dfe72f278abd8e0b322625c65def4 313 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 302 6.7E-47 T 01-11-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MLA2C4_12340 2d7dfe72f278abd8e0b322625c65def4 313 Gene3D G3DSA:3.90.245.10 2 313 3.5E-110 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_11025 7b50ce6c11c724943bc37e04aa73a346 254 SMART SM00327 12 208 7.0E-4 T 01-11-2018 IPR002035 von Willebrand factor, type A MLA2C4_11025 7b50ce6c11c724943bc37e04aa73a346 254 Pfam PF13519 von Willebrand factor type A domain 16 140 1.6E-7 T 01-11-2018 IPR002035 von Willebrand factor, type A MLA2C4_11025 7b50ce6c11c724943bc37e04aa73a346 254 Gene3D G3DSA:3.40.50.410 3 182 2.8E-10 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily MLA2C4_11025 7b50ce6c11c724943bc37e04aa73a346 254 SUPERFAMILY SSF53300 13 180 2.07E-12 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily MLA2C4_28395 c4bd57cd8c3af4ccb4dee000fcc4bd03 311 Pfam PF09991 Predicted membrane protein (DUF2232) 15 301 6.3E-82 T 01-11-2018 IPR018710 Protein of unknown function DUF2232 MLA2C4_16310 f8d668aa802c4b63b859cc4f6e30e3a6 400 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 7 394 2.3E-115 T 01-11-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 MLA2C4_16310 f8d668aa802c4b63b859cc4f6e30e3a6 400 SUPERFAMILY SSF53756 1 392 4.11E-78 T 01-11-2018 MLA2C4_16310 f8d668aa802c4b63b859cc4f6e30e3a6 400 Gene3D G3DSA:3.40.50.2000 4 391 4.7E-120 T 01-11-2018 MLA2C4_16310 f8d668aa802c4b63b859cc4f6e30e3a6 400 Gene3D G3DSA:3.40.50.2000 213 379 4.7E-120 T 01-11-2018 MLA2C4_16310 f8d668aa802c4b63b859cc4f6e30e3a6 400 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 225 374 2.2E-21 T 01-11-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 SUPERFAMILY SSF55486 8 579 8.16E-116 T 01-11-2018 MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 Gene3D G3DSA:1.10.1370.20 227 595 4.7E-128 T 01-11-2018 MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 Gene3D G3DSA:1.10.287.830 180 225 2.9E-14 T 01-11-2018 MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 Pfam PF01432 Peptidase family M3 203 583 3.3E-65 T 01-11-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 Pfam PF08439 Oligopeptidase F 114 182 1.0E-17 T 01-11-2018 IPR013647 Oligopeptidase F, N-terminal domain MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 Gene3D G3DSA:1.20.140.70 25 178 6.6E-42 T 01-11-2018 MLA2C4_18150 43749f841bad2b6b74b7911324858ec0 595 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 9 593 8.9E-183 T 01-11-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 MLA2C4_03760 71c4b6a109258e2c39487952d552a321 300 Pfam PF12849 PBP superfamily domain 43 278 6.3E-36 T 01-11-2018 IPR024370 PBP domain MLA2C4_03760 71c4b6a109258e2c39487952d552a321 300 Gene3D G3DSA:3.40.190.10 52 294 1.9E-81 T 01-11-2018 MLA2C4_03760 71c4b6a109258e2c39487952d552a321 300 Gene3D G3DSA:3.40.190.10 125 252 1.9E-81 T 01-11-2018 MLA2C4_03760 71c4b6a109258e2c39487952d552a321 300 SUPERFAMILY SSF53850 48 296 3.01E-70 T 01-11-2018 MLA2C4_03760 71c4b6a109258e2c39487952d552a321 300 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 3 295 3.8E-97 T 01-11-2018 IPR011862 Phosphate binding protein GO:0042301 MLA2C4_01025 93c32c38a83c8f6ac42e54bf1ebbc32f 270 SUPERFAMILY SSF53850 34 270 5.65E-78 T 01-11-2018 MLA2C4_01025 93c32c38a83c8f6ac42e54bf1ebbc32f 270 Gene3D G3DSA:3.40.190.10 35 266 1.2E-87 T 01-11-2018 MLA2C4_01025 93c32c38a83c8f6ac42e54bf1ebbc32f 270 Gene3D G3DSA:3.40.190.10 116 220 1.2E-87 T 01-11-2018 MLA2C4_01025 93c32c38a83c8f6ac42e54bf1ebbc32f 270 Pfam PF03180 NLPA lipoprotein 35 270 6.9E-87 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_01025 93c32c38a83c8f6ac42e54bf1ebbc32f 270 PIRSF PIRSF002854 1 270 8.7E-92 T 01-11-2018 IPR004872 Lipoprotein NlpA family MLA2C4_06300 bbf278351b7eef3b0b680f4ca928dcae 123 Hamap MF_01861 UPF0738 protein . 3 123 28.883 T 01-11-2018 IPR020908 Uncharacterised protein family UPF0738 MLA2C4_16205 0e480ea17d1c445ea7d6c50b5271425f 381 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 94 369 2.5E-72 T 01-11-2018 IPR010897 Sporulation stage II, protein P MLA2C4_16205 0e480ea17d1c445ea7d6c50b5271425f 381 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 169 374 4.3E-76 T 01-11-2018 IPR010897 Sporulation stage II, protein P MLA2C4_16205 0e480ea17d1c445ea7d6c50b5271425f 381 SUPERFAMILY SSF53187 205 374 3.7E-6 T 01-11-2018 MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 7.6E-171 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 PIRSF PIRSF001589 1 630 5.2E-197 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 Gene3D G3DSA:3.60.20.10 7 192 1.9E-64 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 Pfam PF00733 Asparagine synthase 241 610 8.8E-114 T 01-11-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 SUPERFAMILY SSF56235 1 224 2.92E-62 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 Pfam PF13537 Glutamine amidotransferase domain 51 168 4.1E-46 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain MLA2C4_11260 5be188d556cfb43f50c287590c648351 633 SUPERFAMILY SSF52402 231 605 2.0E-90 T 01-11-2018 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 SUPERFAMILY SSF53474 14 277 1.33E-61 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 Gene3D G3DSA:3.40.50.1820 1 278 7.6E-95 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 Pfam PF00561 alpha/beta hydrolase fold 25 258 3.0E-30 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 1.4E-10 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.4E-10 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.4E-10 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 1.4E-10 T 01-11-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 9.4E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 9.4E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_16490 624313b96524131cbc0142dbf9a71db7 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 9.4E-12 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_18615 8765cb98038e411249e5179d77607271 345 Gene3D G3DSA:1.10.260.150 57 345 2.5E-75 T 01-11-2018 MLA2C4_18615 8765cb98038e411249e5179d77607271 345 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 98 253 6.4E-33 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_18615 8765cb98038e411249e5179d77607271 345 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 253 1.3E-39 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_18710 0509f4192d7eadfe23263c5656dd1a35 618 Gene3D G3DSA:3.20.70.20 42 599 7.9E-203 T 01-11-2018 MLA2C4_18710 0509f4192d7eadfe23263c5656dd1a35 618 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 28 617 3.4E-220 T 01-11-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 MLA2C4_18710 0509f4192d7eadfe23263c5656dd1a35 618 SUPERFAMILY SSF51998 30 596 5.95E-160 T 01-11-2018 MLA2C4_18710 0509f4192d7eadfe23263c5656dd1a35 618 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 29 617 3.6E-206 T 01-11-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 MLA2C4_04130 72cb35a54a34284d0e4e1f3f1a71db2e 122 SMART SM00448 2 118 7.0E-22 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_04130 72cb35a54a34284d0e4e1f3f1a71db2e 122 SUPERFAMILY SSF52172 1 120 4.55E-25 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_04130 72cb35a54a34284d0e4e1f3f1a71db2e 122 Pfam PF00072 Response regulator receiver domain 4 116 1.0E-22 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_04130 72cb35a54a34284d0e4e1f3f1a71db2e 122 Gene3D G3DSA:3.40.50.2300 1 122 2.7E-26 T 01-11-2018 MLA2C4_04040 94408c3268eb2c6e0f5884b960582ccc 216 SUPERFAMILY SSF52540 1 215 2.47E-68 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04040 94408c3268eb2c6e0f5884b960582ccc 216 Pfam PF00005 ABC transporter 19 166 1.8E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_04040 94408c3268eb2c6e0f5884b960582ccc 216 Gene3D G3DSA:3.40.50.300 1 216 5.5E-65 T 01-11-2018 MLA2C4_04040 94408c3268eb2c6e0f5884b960582ccc 216 SMART SM00382 28 212 1.9E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 1.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 288 1.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 302 1.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 1.1E-10 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 Gene3D G3DSA:1.10.287.130 131 184 1.6E-35 T 01-11-2018 MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 SMART SM00387 233 348 2.0E-22 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 Gene3D G3DSA:3.30.565.10 185 344 1.6E-35 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 SUPERFAMILY SSF55874 179 344 2.01E-31 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_23140 9f98e534a1c9cd5a72317532a1e5dab8 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 234 345 9.2E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_05160 c9a999497cf4d4264989211129400679 217 Pfam PF10067 Predicted membrane protein (DUF2306) 54 200 7.4E-54 T 01-11-2018 IPR018750 Protein of unknown function DUF2306, membrane MLA2C4_28045 ed52553eecddecdd2631103d5dc09e12 274 Gene3D G3DSA:3.40.1190.20 1 269 1.2E-90 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_28045 ed52553eecddecdd2631103d5dc09e12 274 SUPERFAMILY SSF53613 4 265 1.36E-78 T 01-11-2018 IPR029056 Ribokinase-like MLA2C4_28045 ed52553eecddecdd2631103d5dc09e12 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 8.8E-88 T 01-11-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_28045 ed52553eecddecdd2631103d5dc09e12 274 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 3.2E-92 T 01-11-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MLA2C4_12380 326bd733d50ea3c72c2181e6a802f6ce 135 Pfam PF13673 Acetyltransferase (GNAT) domain 32 126 3.6E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_12380 326bd733d50ea3c72c2181e6a802f6ce 135 Gene3D G3DSA:3.40.630.30 5 130 9.1E-26 T 01-11-2018 MLA2C4_12380 326bd733d50ea3c72c2181e6a802f6ce 135 SUPERFAMILY SSF55729 9 129 1.03E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 273 286 2.4E-6 T 01-11-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 2.4E-6 T 01-11-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 203 209 2.4E-6 T 01-11-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 260 272 2.4E-6 T 01-11-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 Pfam PF00248 Aldo/keto reductase family 15 317 7.8E-77 T 01-11-2018 IPR023210 NADP-dependent oxidoreductase domain MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 SUPERFAMILY SSF51430 1 320 7.73E-96 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_13830 2f9707c2a028b658fe7013e8ced57e67 329 Gene3D G3DSA:3.20.20.100 1 326 4.4E-111 T 01-11-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 SUPERFAMILY SSF88659 90 172 1.44E-11 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 Gene3D G3DSA:1.10.10.10 115 171 3.0E-11 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 169 2.2E-27 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 SUPERFAMILY SSF88946 4 98 1.81E-21 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 Pfam PF04542 Sigma-70 region 2 14 83 1.2E-16 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 Gene3D G3DSA:1.10.1740.10 1 114 4.2E-20 T 01-11-2018 MLA2C4_03415 3f7dfca57fe4b0855dd998003dfb02f7 185 Pfam PF08281 Sigma-70, region 4 115 165 1.5E-12 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_22270 bcf633e6e896b18b994c327148bb44a3 370 SUPERFAMILY SSF53335 17 361 6.18E-83 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_22270 bcf633e6e896b18b994c327148bb44a3 370 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 79 298 2.7E-45 T 01-11-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 MLA2C4_22270 bcf633e6e896b18b994c327148bb44a3 370 Gene3D G3DSA:3.40.50.12710 5 369 1.4E-96 T 01-11-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 MLA2C4_25970 76970c3929a96aa2ebd209ab849fab03 121 Gene3D G3DSA:3.40.30.10 1 116 9.4E-47 T 01-11-2018 MLA2C4_25970 76970c3929a96aa2ebd209ab849fab03 121 Pfam PF03960 ArsC family 10 114 7.7E-16 T 01-11-2018 IPR006660 Arsenate reductase-like MLA2C4_25970 76970c3929a96aa2ebd209ab849fab03 121 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 4.3E-34 T 01-11-2018 IPR006504 Transcriptional regulator Spx/MgsR MLA2C4_25970 76970c3929a96aa2ebd209ab849fab03 121 SUPERFAMILY SSF52833 2 117 1.52E-36 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 SUPERFAMILY SSF55021 249 340 4.58E-21 T 01-11-2018 MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 SMART SM00930 263 338 5.0E-26 T 01-11-2018 IPR018449 NIL domain MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 Gene3D G3DSA:3.40.50.300 1 244 3.9E-75 T 01-11-2018 MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 SMART SM00382 30 218 6.3E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 SUPERFAMILY SSF52540 1 240 1.95E-82 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 Gene3D G3DSA:3.30.70.260 245 341 1.2E-32 T 01-11-2018 MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 Pfam PF09383 NIL domain 265 337 2.2E-18 T 01-11-2018 IPR018449 NIL domain MLA2C4_25945 9e6ca5296bfb086bdb5e2b96f0c60971 341 Pfam PF00005 ABC transporter 22 169 7.1E-35 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_22050 44ed9942fe5f80e4614e70f7b7b32a38 104 Gene3D G3DSA:1.10.3730.20 1 104 3.5E-30 T 01-11-2018 MLA2C4_22050 44ed9942fe5f80e4614e70f7b7b32a38 104 SUPERFAMILY SSF103481 4 102 1.06E-18 T 01-11-2018 MLA2C4_22050 44ed9942fe5f80e4614e70f7b7b32a38 104 Pfam PF00893 Small Multidrug Resistance protein 1 92 4.1E-27 T 01-11-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MLA2C4_18675 ceeaeb1222b73b4306aa052e2df51118 343 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 237 2.4E-17 T 01-11-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MLA2C4_18675 ceeaeb1222b73b4306aa052e2df51118 343 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 1.4E-23 T 01-11-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MLA2C4_18675 ceeaeb1222b73b4306aa052e2df51118 343 Gene3D G3DSA:3.30.360.10 122 335 1.7E-124 T 01-11-2018 MLA2C4_18675 ceeaeb1222b73b4306aa052e2df51118 343 Gene3D G3DSA:3.40.50.720 6 312 1.7E-124 T 01-11-2018 MLA2C4_18675 ceeaeb1222b73b4306aa052e2df51118 343 SUPERFAMILY SSF51735 2 197 3.83E-51 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_15300 a3b5cee49a027a2f6c49b8f35f64642d 261 SUPERFAMILY SSF53335 29 255 1.18E-41 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_15300 a3b5cee49a027a2f6c49b8f35f64642d 261 Gene3D G3DSA:3.40.50.150 27 261 4.6E-60 T 01-11-2018 MLA2C4_15300 a3b5cee49a027a2f6c49b8f35f64642d 261 Pfam PF08241 Methyltransferase domain 46 142 8.4E-22 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_01245 a910f3b9cbb8e4e473a33e24c2a72553 264 SUPERFAMILY SSF54197 13 130 3.21E-23 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_01245 a910f3b9cbb8e4e473a33e24c2a72553 264 Gene3D G3DSA:3.30.428.10 56 131 5.9E-12 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_01245 a910f3b9cbb8e4e473a33e24c2a72553 264 Pfam PF16285 Domain of unknown function (DUF4931) 8 251 6.0E-126 T 01-11-2018 MLA2C4_01245 a910f3b9cbb8e4e473a33e24c2a72553 264 PIRSF PIRSF031505 1 254 2.4E-126 T 01-11-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative MLA2C4_13255 8c056564e2d12d6d7386e82aa9d7163c 135 SUPERFAMILY SSF54593 6 132 3.22E-40 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_13255 8c056564e2d12d6d7386e82aa9d7163c 135 Gene3D G3DSA:3.30.720.110 75 135 5.3E-32 T 01-11-2018 MLA2C4_13255 8c056564e2d12d6d7386e82aa9d7163c 135 PIRSF PIRSF500687 1 135 5.5E-69 T 01-11-2018 IPR027259 Predicted 3-demethylubiquinone-9 3-methyltransferase, bacterial MLA2C4_13255 8c056564e2d12d6d7386e82aa9d7163c 135 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 132 6.2E-44 T 01-11-2018 IPR028973 PhnB-like MLA2C4_13255 8c056564e2d12d6d7386e82aa9d7163c 135 Gene3D G3DSA:3.30.720.100 10 74 3.2E-33 T 01-11-2018 MLA2C4_13255 8c056564e2d12d6d7386e82aa9d7163c 135 PIRSF PIRSF021700 3 135 8.2E-44 T 01-11-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase MLA2C4_26595 6c2832a2032b3f8ed06cef11db258390 81 SUPERFAMILY SSF52833 1 78 2.6E-21 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_26595 6c2832a2032b3f8ed06cef11db258390 81 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 60 1.8E-18 T 01-11-2018 IPR008554 Glutaredoxin-like MLA2C4_26595 6c2832a2032b3f8ed06cef11db258390 81 Gene3D G3DSA:3.40.30.10 1 75 1.2E-19 T 01-11-2018 MLA2C4_11390 f96d29b7a0881c414719eb97a5b7aa8b 489 Pfam PF07282 Putative transposase DNA-binding domain 380 459 2.4E-6 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_11390 f96d29b7a0881c414719eb97a5b7aa8b 489 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 328 406 3.4E-19 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_11390 f96d29b7a0881c414719eb97a5b7aa8b 489 Pfam PF01385 Probable transposase 250 359 2.7E-19 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 SMART SM00987 50 210 1.9E-36 T 01-11-2018 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 Gene3D G3DSA:3.40.470.10 1 225 1.3E-99 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 01-11-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 SUPERFAMILY SSF52141 4 221 7.2E-93 T 01-11-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 Pfam PF03167 Uracil DNA glycosylase superfamily 54 209 1.2E-27 T 01-11-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 41.345 T 01-11-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 8.0E-82 T 01-11-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_27970 49a31b78bd2995e276467d246d79031f 225 SMART SM00986 50 210 1.9E-36 T 01-11-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MLA2C4_09700 9c695b07efaf3cc3a6280c486be3c413 451 Pfam PF05525 Branched-chain amino acid transport protein 10 432 4.5E-163 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_09700 9c695b07efaf3cc3a6280c486be3c413 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 421 1.9E-157 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_02315 532f1928958e51936d84257224729dd6 249 Pfam PF00005 ABC transporter 19 157 6.3E-29 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_02315 532f1928958e51936d84257224729dd6 249 SUPERFAMILY SSF52540 4 227 2.4E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02315 532f1928958e51936d84257224729dd6 249 Gene3D G3DSA:3.40.50.300 1 221 2.7E-55 T 01-11-2018 MLA2C4_02315 532f1928958e51936d84257224729dd6 249 SMART SM00382 28 207 6.7E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02315 532f1928958e51936d84257224729dd6 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_06940 b96827dc438caad4285e6b123d6c68e7 240 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 9 90 1.3E-27 T 01-11-2018 IPR010627 Peptidase A24A, N-terminal MLA2C4_06940 b96827dc438caad4285e6b123d6c68e7 240 Pfam PF01478 Type IV leader peptidase family 103 204 1.3E-12 T 01-11-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 Gene3D G3DSA:2.60.120.10 73 180 1.2E-18 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 Gene3D G3DSA:1.10.260.40 1 72 1.1E-17 T 01-11-2018 MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 SUPERFAMILY SSF47413 2 68 3.22E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 SUPERFAMILY SSF51182 57 184 1.05E-24 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 SMART SM00530 9 64 2.5E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 Pfam PF07883 Cupin domain 110 180 5.2E-16 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_12420 49e8b6ff7e2c2efc65c2df612b9635a1 186 Pfam PF01381 Helix-turn-helix 13 61 5.0E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 Gene3D G3DSA:1.20.1480.50 166 263 3.1E-12 T 01-11-2018 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 Gene3D G3DSA:1.10.287.950 275 561 2.6E-67 T 01-11-2018 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 Pfam PF00672 HAMP domain 205 254 4.6E-9 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 SMART SM00283 286 561 1.5E-81 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 514 3.8E-46 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 SUPERFAMILY SSF58104 225 561 2.09E-75 T 01-11-2018 MLA2C4_26235 0159438e2764a6da23b183a3fcf51355 564 SMART SM00304 203 257 2.3E-14 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 SMART SM00448 3 116 1.1E-33 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 SMART SM00421 152 209 7.1E-26 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 SUPERFAMILY SSF52172 2 134 2.99E-37 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.7E-15 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.7E-15 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.7E-15 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 SUPERFAMILY SSF46894 149 215 1.7E-22 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 2.4E-21 T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 Gene3D G3DSA:3.40.50.12740 3 215 7.4E-75 T 01-11-2018 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 01-11-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MLA2C4_28035 1822b63337b655875b1aa1f5a8969bd8 215 Pfam PF00072 Response regulator receiver domain 5 117 5.1E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_05230 a1e133334245791e119f2c08d8ba10f4 369 SUPERFAMILY SSF48452 95 270 7.36E-13 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_05230 a1e133334245791e119f2c08d8ba10f4 369 Gene3D G3DSA:1.25.40.10 2 368 8.3E-87 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_22295 95b2c95d1f196dde50b8245c066f6ec9 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 182 6.7E-45 T 01-11-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MLA2C4_22295 95b2c95d1f196dde50b8245c066f6ec9 192 Gene3D G3DSA:3.40.50.10420 1 192 1.9E-75 T 01-11-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MLA2C4_22295 95b2c95d1f196dde50b8245c066f6ec9 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 5 182 5.7E-58 T 01-11-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MLA2C4_22295 95b2c95d1f196dde50b8245c066f6ec9 192 PIRSF PIRSF006806 1 185 7.3E-48 T 01-11-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MLA2C4_22295 95b2c95d1f196dde50b8245c066f6ec9 192 SUPERFAMILY SSF100950 4 188 3.91E-50 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_27250 26669430dbc93cf1a1442999a1d8b065 461 Pfam PF01050 Mannose-6-phosphate isomerase 298 441 1.9E-13 T 01-11-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MLA2C4_27250 26669430dbc93cf1a1442999a1d8b065 461 Gene3D G3DSA:2.60.120.10 339 436 1.5E-17 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_27250 26669430dbc93cf1a1442999a1d8b065 461 SUPERFAMILY SSF51182 189 439 3.06E-30 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_27250 26669430dbc93cf1a1442999a1d8b065 461 SUPERFAMILY SSF53448 1 265 6.33E-48 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_27250 26669430dbc93cf1a1442999a1d8b065 461 Gene3D G3DSA:3.90.550.10 1 332 8.1E-84 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_27250 26669430dbc93cf1a1442999a1d8b065 461 Pfam PF00483 Nucleotidyl transferase 4 270 2.3E-34 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_20355 6a3e06d50fbdb0b1fea0df61a67e1ca3 109 Gene3D G3DSA:1.20.120.910 2 103 1.7E-12 T 01-11-2018 MLA2C4_20355 6a3e06d50fbdb0b1fea0df61a67e1ca3 109 PIRSF PIRSF026544 1 109 8.2E-49 T 01-11-2018 IPR016841 Transcription regulator DksA-related, predicted MLA2C4_02110 10056b87a02c515c35c9430344a35bf7 421 Gene3D G3DSA:3.40.50.720 4 178 1.8E-10 T 01-11-2018 MLA2C4_03400 9e26447f0d0e5ef6a22cc899251abce8 475 Pfam PF00324 Amino acid permease 17 461 8.3E-124 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_03400 9e26447f0d0e5ef6a22cc899251abce8 475 Gene3D G3DSA:1.20.1740.10 7 473 1.4E-69 T 01-11-2018 MLA2C4_03400 9e26447f0d0e5ef6a22cc899251abce8 475 ProSitePatterns PS00218 Amino acid permeases signature. 42 73 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_03400 9e26447f0d0e5ef6a22cc899251abce8 475 PIRSF PIRSF006060 1 474 2.3E-84 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_19885 71a28acea45e38432b236fade7028708 300 SUPERFAMILY SSF51735 131 269 1.53E-17 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_19885 71a28acea45e38432b236fade7028708 300 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 151 290 4.1E-10 T 01-11-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MLA2C4_19885 71a28acea45e38432b236fade7028708 300 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 4 290 3.5E-147 T 01-11-2018 IPR014215 Dipicolinic acid synthetase subunit A MLA2C4_19885 71a28acea45e38432b236fade7028708 300 Gene3D G3DSA:3.40.50.720 7 288 7.2E-104 T 01-11-2018 MLA2C4_19885 71a28acea45e38432b236fade7028708 300 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 4.3E-29 T 01-11-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal MLA2C4_19885 71a28acea45e38432b236fade7028708 300 Gene3D G3DSA:3.40.50.720 126 272 7.2E-104 T 01-11-2018 MLA2C4_15470 f84b8133f7a4aff0545d050c43364fe5 268 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 35 263 5.9E-81 T 01-11-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 MLA2C4_15470 f84b8133f7a4aff0545d050c43364fe5 268 SUPERFAMILY SSF110710 5 266 1.94E-96 T 01-11-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like MLA2C4_03920 1dd392f044045cfe8da46dd2c58f4731 231 SUPERFAMILY SSF48613 1 215 6.68E-75 T 01-11-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MLA2C4_03920 1dd392f044045cfe8da46dd2c58f4731 231 Gene3D G3DSA:1.20.910.10 1 227 9.1E-73 T 01-11-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MLA2C4_03920 1dd392f044045cfe8da46dd2c58f4731 231 PIRSF PIRSF003170 1 218 2.1E-31 T 01-11-2018 IPR026285 TenA_E protein MLA2C4_03920 1dd392f044045cfe8da46dd2c58f4731 231 Pfam PF03070 TENA/THI-4/PQQC family 10 216 2.1E-60 T 01-11-2018 IPR004305 Thiaminase-2/PQQC MLA2C4_03920 1dd392f044045cfe8da46dd2c58f4731 231 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 217 3.5E-73 T 01-11-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 MLA2C4_01560 e6e31f070b11f29860657688dfd519cd 63 Pfam PF14146 Domain of unknown function (DUF4305) 18 54 2.7E-14 T 01-11-2018 IPR025426 Protein of unknown function DUF4305 MLA2C4_01560 e6e31f070b11f29860657688dfd519cd 63 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 63 0.003 T 01-11-2018 MLA2C4_13165 165e9383d86bf8c7f15705feb0885d2d 394 Pfam PF01580 FtsK/SpoIIIE family 128 239 3.7E-14 T 01-11-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MLA2C4_13165 165e9383d86bf8c7f15705feb0885d2d 394 SUPERFAMILY SSF52540 138 363 7.02E-14 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_13165 165e9383d86bf8c7f15705feb0885d2d 394 Gene3D G3DSA:3.40.50.300 110 384 1.9E-44 T 01-11-2018 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 SMART SM01060 18 393 1.4E-177 T 01-11-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 SUPERFAMILY SSF56634 27 456 7.72E-152 T 01-11-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PIRSF PIRSF038928 376 459 9.9E-11 T 01-11-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PIRSF PIRSF038928 6 391 1.3E-151 T 01-11-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 Gene3D G3DSA:2.40.180.10 18 459 3.3E-157 T 01-11-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 Pfam PF06628 Catalase-related immune-responsive 394 455 8.5E-16 T 01-11-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PRINTS PR00067 Catalase signature 115 132 5.1E-51 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PRINTS PR00067 Catalase signature 94 112 5.1E-51 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PRINTS PR00067 Catalase signature 134 152 5.1E-51 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PRINTS PR00067 Catalase signature 331 357 5.1E-51 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PRINTS PR00067 Catalase signature 31 54 5.1E-51 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 PRINTS PR00067 Catalase signature 299 326 5.1E-51 T 01-11-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 ProSitePatterns PS00438 Catalase proximal active site signature. 54 70 - T 01-11-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15890 1ce2072729689c3280177c576b87c2fa 459 Pfam PF00199 Catalase 28 384 3.7E-131 T 01-11-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MLA2C4_15020 87987e078e3b8f335dfa5674e0fecd81 102 ProDom PD068665 YXCD 1 102 6.0E-51 T 01-11-2018 IPR020516 Uncharacterised protein family YxcD MLA2C4_15020 87987e078e3b8f335dfa5674e0fecd81 102 Pfam PF10850 Protein of unknown function (DUF2653) 1 88 2.5E-38 T 01-11-2018 IPR020516 Uncharacterised protein family YxcD MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Pfam PF03793 PASTA domain 584 637 4.7E-12 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 SUPERFAMILY SSF56519 51 220 1.31E-43 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 202 2.1E-22 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 7.9E-88 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Gene3D G3DSA:3.30.10.20 581 637 3.5E-8 T 01-11-2018 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Gene3D G3DSA:3.40.710.10 283 478 1.4E-109 T 01-11-2018 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 SUPERFAMILY SSF54184 584 637 1.57E-11 T 01-11-2018 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 SUPERFAMILY SSF56601 223 568 3.27E-97 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 638 0.0 T 01-11-2018 IPR011927 Stage V sporulation protein D MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Gene3D G3DSA:3.90.1310.30 49 220 8.8E-46 T 01-11-2018 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 Gene3D G3DSA:3.30.450.330 222 560 1.4E-109 T 01-11-2018 MLA2C4_20460 dfb73c75318550d98775a40cf595b39c 638 SMART SM00740 580 638 1.3E-14 T 01-11-2018 IPR005543 PASTA domain MLA2C4_27370 60e511b62aeb444efcd0471a4343a1ea 434 SUPERFAMILY SSF55205 2 418 1.8E-142 T 01-11-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MLA2C4_27370 60e511b62aeb444efcd0471a4343a1ea 434 Gene3D G3DSA:3.65.10.10 7 414 1.4E-177 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MLA2C4_27370 60e511b62aeb444efcd0471a4343a1ea 434 Gene3D G3DSA:3.65.10.10 21 231 1.4E-177 T 01-11-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MLA2C4_27370 60e511b62aeb444efcd0471a4343a1ea 434 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 2.0E-176 T 01-11-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_27370 60e511b62aeb444efcd0471a4343a1ea 434 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 407 4.4E-117 T 01-11-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MLA2C4_27370 60e511b62aeb444efcd0471a4343a1ea 434 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.452 T 01-11-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MLA2C4_04525 7c00a4f247e1e8626eb9f04c06e110da 133 Gene3D G3DSA:3.10.450.50 1 133 1.4E-35 T 01-11-2018 MLA2C4_04525 7c00a4f247e1e8626eb9f04c06e110da 133 Pfam PF12680 SnoaL-like domain 13 116 1.6E-7 T 01-11-2018 IPR037401 SnoaL-like domain MLA2C4_04525 7c00a4f247e1e8626eb9f04c06e110da 133 SUPERFAMILY SSF54427 3 131 1.22E-30 T 01-11-2018 IPR032710 NTF2-like domain superfamily MLA2C4_10570 527f3191dc984ec1997e12d184de7a86 237 Pfam PF13649 Methyltransferase domain 46 137 4.4E-16 T 01-11-2018 MLA2C4_10570 527f3191dc984ec1997e12d184de7a86 237 Gene3D G3DSA:2.20.25.110 145 206 2.3E-46 T 01-11-2018 MLA2C4_10570 527f3191dc984ec1997e12d184de7a86 237 SUPERFAMILY SSF53335 10 229 2.04E-40 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_10570 527f3191dc984ec1997e12d184de7a86 237 Gene3D G3DSA:3.40.50.150 13 227 2.3E-46 T 01-11-2018 MLA2C4_01370 64786c651c8f524b0629e216b766b947 471 Pfam PF13520 Amino acid permease 26 442 5.2E-64 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_01370 64786c651c8f524b0629e216b766b947 471 PIRSF PIRSF006060 10 471 2.3E-100 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_01370 64786c651c8f524b0629e216b766b947 471 Gene3D G3DSA:1.20.1740.10 20 468 1.0E-134 T 01-11-2018 MLA2C4_17620 41a057f5b190d0614c3ccbbfbad37477 398 Gene3D G3DSA:1.20.1250.20 3 200 6.3E-24 T 01-11-2018 MLA2C4_17620 41a057f5b190d0614c3ccbbfbad37477 398 Gene3D G3DSA:1.20.1250.20 201 382 6.3E-19 T 01-11-2018 MLA2C4_17620 41a057f5b190d0614c3ccbbfbad37477 398 SUPERFAMILY SSF103473 8 381 1.83E-50 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_17620 41a057f5b190d0614c3ccbbfbad37477 398 Pfam PF07690 Major Facilitator Superfamily 12 302 6.2E-24 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_15875 4cd72884976313b3de7a2fe7b78a362e 369 Pfam PF13210 Domain of unknown function (DUF4018) 48 239 9.3E-89 T 01-11-2018 IPR025089 Protein of unknown function DUF4018 MLA2C4_05770 caf8e7db81a0d2973ee2c5f5d205b937 169 SUPERFAMILY SSF55729 2 166 2.53E-28 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_05770 caf8e7db81a0d2973ee2c5f5d205b937 169 Gene3D G3DSA:3.40.630.30 1 168 1.7E-37 T 01-11-2018 MLA2C4_05770 caf8e7db81a0d2973ee2c5f5d205b937 169 Pfam PF00583 Acetyltransferase (GNAT) family 41 141 4.6E-17 T 01-11-2018 IPR000182 GNAT domain MLA2C4_16825 90b1fc01d5ce805d72aa07a9a38acf8f 130 Gene3D G3DSA:3.10.180.10 1 130 5.1E-32 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_16825 90b1fc01d5ce805d72aa07a9a38acf8f 130 SUPERFAMILY SSF54593 1 127 1.01E-28 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_16825 90b1fc01d5ce805d72aa07a9a38acf8f 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 1.9E-14 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 3.4E-20 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 SUPERFAMILY SSF52172 3 118 5.55E-33 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 SUPERFAMILY SSF46894 128 226 2.83E-23 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 SMART SM00448 2 112 1.4E-28 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 SMART SM00862 150 225 1.6E-15 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 Gene3D G3DSA:3.40.50.2300 2 123 4.6E-28 T 01-11-2018 MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 Pfam PF00072 Response regulator receiver domain 4 112 5.0E-19 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_13810 fdca257dc030f953ffd3dfd656652635 235 Gene3D G3DSA:1.10.10.10 124 227 2.5E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25795 5f16a559f03f51d9804114835b0551bf 193 Gene3D G3DSA:3.40.50.360 1 192 1.0E-60 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_25795 5f16a559f03f51d9804114835b0551bf 193 Pfam PF02525 Flavodoxin-like fold 1 187 9.3E-53 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_25795 5f16a559f03f51d9804114835b0551bf 193 SUPERFAMILY SSF52218 1 193 2.35E-59 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_27175 5061a14d31353eb965d45767ca7fd9fb 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_27175 5061a14d31353eb965d45767ca7fd9fb 226 SMART SM00382 30 217 1.2E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_27175 5061a14d31353eb965d45767ca7fd9fb 226 SUPERFAMILY SSF52540 1 222 2.88E-75 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27175 5061a14d31353eb965d45767ca7fd9fb 226 Gene3D G3DSA:3.40.50.300 1 225 3.9E-67 T 01-11-2018 MLA2C4_27175 5061a14d31353eb965d45767ca7fd9fb 226 Pfam PF00005 ABC transporter 21 169 2.8E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 SUPERFAMILY SSF46785 6 80 3.41E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 PIRSF PIRSF026546 5 211 3.0E-101 T 01-11-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 SUPERFAMILY SSF54631 75 206 3.54E-23 T 01-11-2018 MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 SMART SM00116 87 135 0.0033 T 01-11-2018 IPR000644 CBS domain MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 SMART SM00116 154 205 0.41 T 01-11-2018 IPR000644 CBS domain MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 Pfam PF08279 HTH domain 10 62 5.8E-12 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 Gene3D G3DSA:1.10.10.10 6 63 8.6E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 Pfam PF00571 CBS domain 83 135 8.1E-6 T 01-11-2018 IPR000644 CBS domain MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 Pfam PF00571 CBS domain 148 205 2.4E-5 T 01-11-2018 IPR000644 CBS domain MLA2C4_22445 cce94c72eec0860e164adf1be5ca3db7 211 Gene3D G3DSA:3.10.580.10 64 211 3.5E-57 T 01-11-2018 MLA2C4_04405 c23cf2e021e1e1a9e5ccb16efe26349a 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 237 6.5E-7 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_04405 c23cf2e021e1e1a9e5ccb16efe26349a 334 SUPERFAMILY SSF161098 75 265 1.03E-12 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_04405 c23cf2e021e1e1a9e5ccb16efe26349a 334 Gene3D G3DSA:1.10.3720.10 69 301 1.0E-13 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01040 2e5c249553e1b6962a04052aeb59711f 478 Pfam PF04030 D-arabinono-1,4-lactone oxidase 204 474 1.5E-6 T 01-11-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 MLA2C4_01040 2e5c249553e1b6962a04052aeb59711f 478 Pfam PF01565 FAD binding domain 47 180 6.7E-28 T 01-11-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MLA2C4_01040 2e5c249553e1b6962a04052aeb59711f 478 Gene3D G3DSA:3.30.465.10 97 211 5.0E-28 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_01040 2e5c249553e1b6962a04052aeb59711f 478 SUPERFAMILY SSF55103 186 466 8.83E-19 T 01-11-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MLA2C4_01040 2e5c249553e1b6962a04052aeb59711f 478 Gene3D G3DSA:1.10.45.10 441 477 3.4E-5 T 01-11-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MLA2C4_01040 2e5c249553e1b6962a04052aeb59711f 478 SUPERFAMILY SSF56176 29 209 4.07E-39 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_26485 5d50be761e62ee276104ed1a6cfd8d54 250 Pfam PF00005 ABC transporter 21 164 1.3E-24 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_26485 5d50be761e62ee276104ed1a6cfd8d54 250 SUPERFAMILY SSF52540 2 226 1.36E-54 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26485 5d50be761e62ee276104ed1a6cfd8d54 250 Gene3D G3DSA:3.40.50.300 1 243 2.5E-58 T 01-11-2018 MLA2C4_26485 5d50be761e62ee276104ed1a6cfd8d54 250 SMART SM00382 26 213 1.1E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_24960 eb9c0548f6bfb2fb9de56db56633d8c6 187 Gene3D G3DSA:3.40.1050.10 2 183 6.5E-48 T 01-11-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MLA2C4_24960 eb9c0548f6bfb2fb9de56db56633d8c6 187 SUPERFAMILY SSF53056 1 181 3.01E-43 T 01-11-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MLA2C4_24960 eb9c0548f6bfb2fb9de56db56633d8c6 187 SMART SM00947 26 182 9.0E-41 T 01-11-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MLA2C4_24960 eb9c0548f6bfb2fb9de56db56633d8c6 187 Pfam PF00484 Carbonic anhydrase 33 178 2.4E-20 T 01-11-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MLA2C4_04380 890f3e468778c0bceaa4e896df425644 391 Pfam PF12704 MacB-like periplasmic core domain 21 229 3.3E-23 T 01-11-2018 IPR025857 MacB-like periplasmic core domain MLA2C4_04380 890f3e468778c0bceaa4e896df425644 391 Pfam PF02687 FtsX-like permease family 297 381 9.0E-10 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_09820 abcd1791e14bb3a4dd92c12b61872fe7 233 Pfam PF00005 ABC transporter 19 161 7.0E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09820 abcd1791e14bb3a4dd92c12b61872fe7 233 SMART SM00382 28 217 3.3E-6 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09820 abcd1791e14bb3a4dd92c12b61872fe7 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_09820 abcd1791e14bb3a4dd92c12b61872fe7 233 Gene3D G3DSA:3.40.50.300 2 233 5.4E-55 T 01-11-2018 MLA2C4_09820 abcd1791e14bb3a4dd92c12b61872fe7 233 SUPERFAMILY SSF52540 3 229 5.45E-51 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_26215 aaba881b89eccef8fb73ef80104d5441 300 SUPERFAMILY SSF103481 191 282 8.76E-8 T 01-11-2018 MLA2C4_26215 aaba881b89eccef8fb73ef80104d5441 300 Pfam PF00892 EamA-like transporter family 150 281 1.6E-14 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_15285 ff7fe9ece41a5d36d1937bc2b8c005dd 80 Pfam PF04226 Transglycosylase associated protein 31 75 4.0E-11 T 01-11-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 Gene3D G3DSA:3.40.50.850 1 207 5.2E-76 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PRINTS PR01398 Isochorismatase signature 112 134 2.3E-45 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PRINTS PR01398 Isochorismatase signature 2 14 2.3E-45 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PRINTS PR01398 Isochorismatase signature 186 203 2.3E-45 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PRINTS PR01398 Isochorismatase signature 80 99 2.3E-45 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PRINTS PR01398 Isochorismatase signature 168 186 2.3E-45 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PRINTS PR01398 Isochorismatase signature 63 80 2.3E-45 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 Pfam PF00550 Phosphopantetheine attachment site 225 289 9.8E-10 T 01-11-2018 IPR009081 Phosphopantetheine binding ACP domain MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 PIRSF PIRSF001111 1 297 1.3E-133 T 01-11-2018 IPR016291 Isochorismatase GO:0008908 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 Gene3D G3DSA:1.10.1200.10 221 293 9.1E-24 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 SUPERFAMILY SSF52499 1 215 1.09E-62 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 SUPERFAMILY SSF47336 221 292 2.36E-10 T 01-11-2018 IPR036736 ACP-like superfamily MLA2C4_12205 bbf8393d4f26ce37cb9cddecf536110a 297 Pfam PF00857 Isochorismatase family 32 203 3.4E-39 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_06385 d498d992ea0d33e0ed27db33bee829ca 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 306 4.3E-92 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_06385 d498d992ea0d33e0ed27db33bee829ca 322 Gene3D G3DSA:3.90.25.10 192 313 1.4E-128 T 01-11-2018 MLA2C4_06385 d498d992ea0d33e0ed27db33bee829ca 322 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 320 2.7E-150 T 01-11-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MLA2C4_06385 d498d992ea0d33e0ed27db33bee829ca 322 SUPERFAMILY SSF51735 1 317 1.45E-92 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_06385 d498d992ea0d33e0ed27db33bee829ca 322 Gene3D G3DSA:3.40.50.720 2 305 1.4E-128 T 01-11-2018 MLA2C4_08185 d6c2dfba5a019b1c414ce40f77f4224a 184 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 3.5E-70 T 01-11-2018 IPR010697 Protein of unknown function DUF1273 MLA2C4_08185 d6c2dfba5a019b1c414ce40f77f4224a 184 PIRSF PIRSF021290 1 179 2.8E-74 T 01-11-2018 IPR010697 Protein of unknown function DUF1273 MLA2C4_08185 d6c2dfba5a019b1c414ce40f77f4224a 184 Gene3D G3DSA:3.40.50.450 1 180 4.1E-69 T 01-11-2018 MLA2C4_08185 d6c2dfba5a019b1c414ce40f77f4224a 184 Hamap MF_01575 UPF0398 protein . 1 177 36.006 T 01-11-2018 IPR010697 Protein of unknown function DUF1273 MLA2C4_08185 d6c2dfba5a019b1c414ce40f77f4224a 184 SUPERFAMILY SSF102405 1 177 4.58E-63 T 01-11-2018 MLA2C4_09955 56464a2b0d2b279497e4a4652fd91816 116 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 113 4.6E-17 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_09955 56464a2b0d2b279497e4a4652fd91816 116 SUPERFAMILY SSF159121 32 113 1.7E-21 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_09955 56464a2b0d2b279497e4a4652fd91816 116 Pfam PF06486 Protein of unknown function (DUF1093) 34 103 1.7E-16 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_09955 56464a2b0d2b279497e4a4652fd91816 116 Gene3D G3DSA:2.40.50.480 31 116 8.7E-20 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_17840 ae948a10d1f2bd4953e4c2f90815fb77 240 PIRSF PIRSF038953 6 240 1.4E-60 T 01-11-2018 IPR014244 RNA polymerase sigma-I type MLA2C4_17840 ae948a10d1f2bd4953e4c2f90815fb77 240 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 13 235 28.08 T 01-11-2018 IPR014244 RNA polymerase sigma-I type MLA2C4_17840 ae948a10d1f2bd4953e4c2f90815fb77 240 Pfam PF04542 Sigma-70 region 2 32 101 3.0E-8 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_17840 ae948a10d1f2bd4953e4c2f90815fb77 240 Gene3D G3DSA:1.10.1740.10 17 98 6.2E-10 T 01-11-2018 MLA2C4_17840 ae948a10d1f2bd4953e4c2f90815fb77 240 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 18 233 7.7E-96 T 01-11-2018 IPR014244 RNA polymerase sigma-I type MLA2C4_17840 ae948a10d1f2bd4953e4c2f90815fb77 240 SUPERFAMILY SSF88946 22 100 5.3E-16 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 1.6E-24 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 Gene3D G3DSA:1.10.10.10 132 221 8.4E-31 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 SUPERFAMILY SSF52172 1 179 8.79E-39 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 SMART SM00862 148 219 1.6E-26 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 SMART SM00448 2 112 5.6E-38 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_26205 ecee550341d3b2bf42e6e234552d0c9a 221 Gene3D G3DSA:3.40.50.2300 1 131 1.7E-36 T 01-11-2018 MLA2C4_12330 ca2a4895c7e4c0c68f8bd28b2d3ede59 262 Gene3D G3DSA:3.40.50.150 49 249 1.5E-49 T 01-11-2018 MLA2C4_12330 ca2a4895c7e4c0c68f8bd28b2d3ede59 262 SUPERFAMILY SSF53335 28 261 5.43E-42 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_12330 ca2a4895c7e4c0c68f8bd28b2d3ede59 262 Gene3D G3DSA:2.20.25.570 151 219 1.5E-49 T 01-11-2018 MLA2C4_12330 ca2a4895c7e4c0c68f8bd28b2d3ede59 262 Pfam PF13649 Methyltransferase domain 49 143 3.8E-17 T 01-11-2018 MLA2C4_16000 495026960c90c88d72ae0838ce6b45c9 251 Pfam PF02517 CAAX protease self-immunity 110 211 7.6E-13 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_21275 0abac2829c10a74e7582d3a08c713ea4 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 111 1.7E-41 T 01-11-2018 IPR005562 SpoVA MLA2C4_21275 0abac2829c10a74e7582d3a08c713ea4 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 1.0E-54 T 01-11-2018 IPR014204 Sporulation stage V, protein AE MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 19 429 38.822 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 Pfam PF01566 Natural resistance-associated macrophage protein 55 403 4.1E-118 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 167 188 8.4E-34 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 217 240 8.4E-34 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 142 161 8.4E-34 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 114 140 8.4E-34 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 319 338 8.4E-34 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_09570 561c927dc12c88e71bce23e016fc762c 431 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 34 397 2.0E-125 T 01-11-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MLA2C4_17095 6745680d5d0f5ce5606466c4bc5aa6c4 131 SUPERFAMILY SSF159238 2 131 6.15E-31 T 01-11-2018 IPR023159 SO1590-like superfamily MLA2C4_17095 6745680d5d0f5ce5606466c4bc5aa6c4 131 Gene3D G3DSA:2.40.350.10 1 128 2.1E-23 T 01-11-2018 IPR023159 SO1590-like superfamily MLA2C4_17095 6745680d5d0f5ce5606466c4bc5aa6c4 131 Pfam PF11528 Protein of unknown function (DUF3224) 4 123 1.3E-20 T 01-11-2018 IPR021607 Protein of unknown function DUF3224 MLA2C4_27700 fa44029cc002e01f774e04febe2311a6 285 SUPERFAMILY SSF47413 5 64 2.17E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_27700 fa44029cc002e01f774e04febe2311a6 285 SUPERFAMILY SSF48452 155 256 5.52E-8 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_27700 fa44029cc002e01f774e04febe2311a6 285 Gene3D G3DSA:1.25.40.10 1 285 1.8E-109 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_27700 fa44029cc002e01f774e04febe2311a6 285 Pfam PF01381 Helix-turn-helix 10 60 2.4E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_27700 fa44029cc002e01f774e04febe2311a6 285 SMART SM00530 9 63 1.7E-11 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 SUPERFAMILY SSF56801 6 495 8.24E-150 T 01-11-2018 MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 01-11-2018 IPR020845 AMP-binding, conserved site MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 Gene3D G3DSA:3.40.50.12780 2 396 3.3E-119 T 01-11-2018 MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 Pfam PF00501 AMP-binding enzyme 10 399 3.5E-109 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 Gene3D G3DSA:3.30.300.310 397 496 4.2E-32 T 01-11-2018 MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 29 488 2.9E-100 T 01-11-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 MLA2C4_09790 3e5e855aa6879dc7cba792db69a302f1 496 Pfam PF13193 AMP-binding enzyme C-terminal domain 408 483 4.6E-18 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_18015 2464f17a99934acd394f4a070b4dd2de 220 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 5.5E-29 T 01-11-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MLA2C4_18015 2464f17a99934acd394f4a070b4dd2de 220 SUPERFAMILY SSF102588 3 219 4.45E-50 T 01-11-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MLA2C4_18015 2464f17a99934acd394f4a070b4dd2de 220 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 219 4.8E-101 T 01-11-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 MLA2C4_18015 2464f17a99934acd394f4a070b4dd2de 220 Gene3D G3DSA:3.40.50.10320 1 215 2.4E-49 T 01-11-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MLA2C4_13485 3b825a27afdf7da755a3fd1ac8870463 513 Gene3D G3DSA:3.90.226.10 249 512 1.5E-83 T 01-11-2018 MLA2C4_13485 3b825a27afdf7da755a3fd1ac8870463 513 Gene3D G3DSA:3.90.226.10 2 248 3.1E-76 T 01-11-2018 MLA2C4_13485 3b825a27afdf7da755a3fd1ac8870463 513 SUPERFAMILY SSF52096 215 490 1.66E-81 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_13485 3b825a27afdf7da755a3fd1ac8870463 513 Pfam PF01039 Carboxyl transferase domain 30 510 5.3E-158 T 01-11-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MLA2C4_13485 3b825a27afdf7da755a3fd1ac8870463 513 SUPERFAMILY SSF52096 8 253 4.55E-67 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_13555 94f26ff8ca4ba937eba7352d14f10805 282 Pfam PF00583 Acetyltransferase (GNAT) family 34 134 6.6E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_13555 94f26ff8ca4ba937eba7352d14f10805 282 Gene3D G3DSA:3.40.630.30 8 142 7.2E-21 T 01-11-2018 MLA2C4_13555 94f26ff8ca4ba937eba7352d14f10805 282 SUPERFAMILY SSF55729 182 271 2.06E-12 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_13555 94f26ff8ca4ba937eba7352d14f10805 282 Gene3D G3DSA:3.40.630.30 143 275 7.6E-13 T 01-11-2018 MLA2C4_13555 94f26ff8ca4ba937eba7352d14f10805 282 SUPERFAMILY SSF55729 12 146 2.16E-22 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_13555 94f26ff8ca4ba937eba7352d14f10805 282 Pfam PF13673 Acetyltransferase (GNAT) domain 173 276 2.3E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 SUPERFAMILY SSF53927 3 144 1.07E-43 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 Pfam PF01872 RibD C-terminal domain 147 354 8.1E-57 T 01-11-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 SUPERFAMILY SSF53597 147 356 2.62E-62 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 355 7.1E-124 T 01-11-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 Gene3D G3DSA:3.40.430.10 136 361 1.5E-77 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 357 5.5E-71 T 01-11-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 3.4E-20 T 01-11-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 PIRSF PIRSF006769 1 362 4.8E-134 T 01-11-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MLA2C4_21510 efeb402a099ec882c03c9c8cb9ae1894 370 Gene3D G3DSA:3.40.140.10 1 135 1.1E-42 T 01-11-2018 MLA2C4_14110 27f0aa439f96f2fcdeb6fcae0e8b2d86 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 31 2.9E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_14110 27f0aa439f96f2fcdeb6fcae0e8b2d86 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 29 9.8E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 SUPERFAMILY SSF88946 1 98 5.97E-23 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 Gene3D G3DSA:1.10.10.10 111 172 4.4E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 Gene3D G3DSA:1.10.1740.10 1 110 1.4E-21 T 01-11-2018 MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 TIGRFAM TIGR02954 Sig70_famx3: RNA polymerase sigma-70 factor, TIGR02954 family 4 172 1.8E-56 T 01-11-2018 IPR014300 RNA polymerase sigma-V type MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 166 5.4E-27 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 Pfam PF08281 Sigma-70, region 4 114 165 4.2E-16 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 Pfam PF04542 Sigma-70 region 2 23 88 5.2E-13 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_25350 3975d0d9162e1aa12532d713abe73154 176 SUPERFAMILY SSF88659 109 171 1.64E-17 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_14640 00bf9359e314ba9955b029db14bbbea0 79 Pfam PF13129 Protein of unknown function (DUF3953) 32 72 1.0E-6 T 01-11-2018 IPR025018 Protein of unknown function DUF3953 MLA2C4_17215 81b855dcccc6d7606ecaefb055d95f96 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 125 3.5E-10 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_17215 81b855dcccc6d7606ecaefb055d95f96 152 SUPERFAMILY SSF54593 1 135 1.88E-18 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_17215 81b855dcccc6d7606ecaefb055d95f96 152 Gene3D G3DSA:3.10.180.10 2 127 1.6E-26 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 SUPERFAMILY SSF53383 59 467 2.04E-138 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 Gene3D G3DSA:3.90.1150.10 45 463 6.2E-169 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 Pfam PF00202 Aminotransferase class-III 62 465 2.0E-134 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 Gene3D G3DSA:3.40.640.10 98 365 6.2E-169 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 49 468 7.3E-199 T 01-11-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 PIRSF PIRSF000521 7 169 1.9E-11 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 PIRSF PIRSF000521 163 470 5.9E-41 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_01930 1bc3afa5841fabab63193603875790d0 479 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 282 319 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 Pfam PF13411 MerR HTH family regulatory protein 2 67 3.5E-20 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 SUPERFAMILY SSF46955 2 110 9.16E-30 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 SMART SM00422 2 70 3.0E-19 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 Gene3D G3DSA:1.10.1660.10 1 119 1.0E-30 T 01-11-2018 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.7E-7 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 3.7E-7 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_04555 f0972f9235f57a98266b54bd50d83be9 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 3.7E-7 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_04945 8bfe2ba5819d73feb1a72d7590db0401 314 Gene3D G3DSA:1.10.10.10 1 64 1.6E-5 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04945 8bfe2ba5819d73feb1a72d7590db0401 314 Pfam PF08279 HTH domain 8 60 2.1E-6 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_04945 8bfe2ba5819d73feb1a72d7590db0401 314 Pfam PF13280 WYL domain 142 309 4.1E-35 T 01-11-2018 IPR026881 WYL domain MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 Pfam PF08281 Sigma-70, region 4 119 171 5.3E-14 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 Gene3D G3DSA:1.10.1740.10 1 98 7.3E-24 T 01-11-2018 MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 Pfam PF04542 Sigma-70 region 2 23 84 1.1E-14 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 Gene3D G3DSA:1.10.10.10 99 177 2.8E-17 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 SUPERFAMILY SSF88946 14 98 9.42E-21 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 SUPERFAMILY SSF88659 115 177 5.79E-15 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_05525 b197d651c9fd8992d298aa038de42fca 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 174 4.3E-31 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_24965 bc328e7887c46786210cb7b6bc9ae8f8 449 PIRSF PIRSF006446 1 449 5.4E-174 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MLA2C4_24965 bc328e7887c46786210cb7b6bc9ae8f8 449 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 433 7.7E-175 T 01-11-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MLA2C4_11210 d688551309929d268990d206f2368b86 211 Pfam PF02525 Flavodoxin-like fold 2 206 3.4E-47 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_11210 d688551309929d268990d206f2368b86 211 Gene3D G3DSA:3.40.50.360 1 211 2.4E-66 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_11210 d688551309929d268990d206f2368b86 211 SUPERFAMILY SSF52218 1 211 1.02E-53 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_11210 d688551309929d268990d206f2368b86 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 29.957 T 01-11-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MLA2C4_15205 bb3aec82049154a80c0965d9b703920a 143 SUPERFAMILY SSF55729 1 117 2.27E-18 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15205 bb3aec82049154a80c0965d9b703920a 143 Pfam PF00583 Acetyltransferase (GNAT) family 33 109 3.8E-9 T 01-11-2018 IPR000182 GNAT domain MLA2C4_15205 bb3aec82049154a80c0965d9b703920a 143 Gene3D G3DSA:3.40.630.30 2 134 7.7E-17 T 01-11-2018 MLA2C4_20390 abd3ef0c3eec88d3409a6820b90ac103 272 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 35 266 3.0E-55 T 01-11-2018 IPR003730 Multi-copper polyphenol oxidoreductase MLA2C4_20390 abd3ef0c3eec88d3409a6820b90ac103 272 SUPERFAMILY SSF64438 11 268 9.71E-80 T 01-11-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MLA2C4_20390 abd3ef0c3eec88d3409a6820b90ac103 272 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 28 264 4.7E-71 T 01-11-2018 IPR003730 Multi-copper polyphenol oxidoreductase MLA2C4_20390 abd3ef0c3eec88d3409a6820b90ac103 272 Gene3D G3DSA:3.60.140.10 6 271 1.9E-89 T 01-11-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily MLA2C4_21560 484283710925fba05248ea507669dfa2 462 Pfam PF00202 Aminotransferase class-III 41 455 4.3E-125 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 Gene3D G3DSA:3.90.1150.10 22 455 7.3E-170 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 Gene3D G3DSA:3.40.640.10 76 353 7.3E-170 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 26 455 2.0E-175 T 01-11-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 263 300 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 PIRSF PIRSF000521 40 458 1.8E-41 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 14 458 52.778 T 01-11-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MLA2C4_21560 484283710925fba05248ea507669dfa2 462 SUPERFAMILY SSF53383 23 455 1.34E-133 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_24130 95a1b0c0ee210aca040d159ecf904927 143 SUPERFAMILY SSF54593 2 137 4.35E-33 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_24130 95a1b0c0ee210aca040d159ecf904927 143 Gene3D G3DSA:3.10.180.10 9 143 1.1E-43 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_24130 95a1b0c0ee210aca040d159ecf904927 143 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 136 1.4E-8 T 01-11-2018 IPR028973 PhnB-like MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 SUPERFAMILY SSF54631 204 338 9.1E-28 T 01-11-2018 MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 Pfam PF00571 CBS domain 286 334 2.9E-4 T 01-11-2018 IPR000644 CBS domain MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 Gene3D G3DSA:3.30.465.10 346 434 1.2E-13 T 01-11-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 SMART SM01091 351 430 1.9E-13 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 Gene3D G3DSA:3.10.580.10 195 345 3.5E-49 T 01-11-2018 MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 SUPERFAMILY SSF56176 349 429 4.91E-13 T 01-11-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 Pfam PF03471 Transporter associated domain 359 429 2.9E-12 T 01-11-2018 IPR005170 Transporter-associated domain MLA2C4_10430 a425671b4e0b50368e63c31a37e00dfd 435 Pfam PF01595 Domain of unknown function DUF21 7 201 9.6E-49 T 01-11-2018 IPR002550 CNNM, transmembrane domain MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 SUPERFAMILY SSF53474 6 264 6.54E-37 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 Gene3D G3DSA:3.40.50.1820 1 268 1.4E-49 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 1.9E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.9E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.9E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.9E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_19570 e9a4b6fad77372ba45caf3f2a2556431 271 Pfam PF12146 Serine aminopeptidase, S33 21 251 2.3E-9 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_10370 f3dfc6c43e551e43773b5607a2f2f91c 459 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 375 455 5.5E-19 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MLA2C4_10370 f3dfc6c43e551e43773b5607a2f2f91c 459 Pfam PF01943 Polysaccharide biosynthesis protein 7 319 3.6E-42 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_10370 f3dfc6c43e551e43773b5607a2f2f91c 459 PIRSF PIRSF038958 1 458 9.5E-106 T 01-11-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type MLA2C4_03135 ef5b1274fc4893d4ba27cd56bc6cd973 623 Gene3D G3DSA:3.20.20.190 352 590 1.1E-56 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_03135 ef5b1274fc4893d4ba27cd56bc6cd973 623 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 13 350 1.8E-80 T 01-11-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain MLA2C4_03135 ef5b1274fc4893d4ba27cd56bc6cd973 623 SUPERFAMILY SSF51695 360 586 9.94E-62 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_03135 ef5b1274fc4893d4ba27cd56bc6cd973 623 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 366 581 1.7E-26 T 01-11-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MLA2C4_13480 2eabb965f821bc971ae324f78cd8dcc7 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 1.9E-71 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MLA2C4_13480 2eabb965f821bc971ae324f78cd8dcc7 262 Gene3D G3DSA:3.90.226.10 1 202 1.3E-73 T 01-11-2018 MLA2C4_13480 2eabb965f821bc971ae324f78cd8dcc7 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MLA2C4_13480 2eabb965f821bc971ae324f78cd8dcc7 262 Gene3D G3DSA:1.10.12.10 203 262 3.6E-27 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MLA2C4_13480 2eabb965f821bc971ae324f78cd8dcc7 262 SUPERFAMILY SSF52096 4 261 8.64E-85 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_14060 9745b074518887104e4a751bb713224b 351 Pfam PF01385 Probable transposase 208 251 9.7E-10 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_14060 9745b074518887104e4a751bb713224b 351 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 219 292 1.2E-13 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_14060 9745b074518887104e4a751bb713224b 351 Pfam PF12323 Helix-turn-helix domain 4 48 4.0E-18 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_14060 9745b074518887104e4a751bb713224b 351 Pfam PF07282 Putative transposase DNA-binding domain 265 335 1.6E-23 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_13685 d3d621d2ae91f9f8dc06b242c9c508cf 107 SUPERFAMILY SSF46785 13 99 5.56E-27 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_13685 d3d621d2ae91f9f8dc06b242c9c508cf 107 Gene3D G3DSA:1.10.10.10 8 107 2.5E-32 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_13685 d3d621d2ae91f9f8dc06b242c9c508cf 107 Pfam PF01638 HxlR-like helix-turn-helix 15 100 1.4E-32 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_23605 fccea02acdd49c4a54f832b68a900eb9 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.5E-15 T 01-11-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MLA2C4_23605 fccea02acdd49c4a54f832b68a900eb9 107 SUPERFAMILY SSF54909 1 96 1.12E-24 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_23605 fccea02acdd49c4a54f832b68a900eb9 107 Gene3D G3DSA:3.30.70.100 1 106 1.2E-32 T 01-11-2018 MLA2C4_23605 fccea02acdd49c4a54f832b68a900eb9 107 Hamap MF_01272 Heme oxygenase (staphylobilin-producing) [isdG]. 1 102 27.09 T 01-11-2018 IPR023953 Heme oxygenase IsdG GO:0004392|GO:0033212|GO:0055114 MLA2C4_28425 5e53331c3a1c88f8909f69374a9fa531 293 Pfam PF00924 Mechanosensitive ion channel 77 274 9.7E-47 T 01-11-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MLA2C4_28425 5e53331c3a1c88f8909f69374a9fa531 293 SUPERFAMILY SSF82689 186 284 4.18E-18 T 01-11-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MLA2C4_28425 5e53331c3a1c88f8909f69374a9fa531 293 SUPERFAMILY SSF82861 30 118 3.53E-14 T 01-11-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MLA2C4_28425 5e53331c3a1c88f8909f69374a9fa531 293 Gene3D G3DSA:3.30.70.100 185 272 2.3E-23 T 01-11-2018 MLA2C4_28425 5e53331c3a1c88f8909f69374a9fa531 293 Gene3D G3DSA:2.30.30.60 135 183 1.9E-21 T 01-11-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MLA2C4_28425 5e53331c3a1c88f8909f69374a9fa531 293 SUPERFAMILY SSF50182 120 182 3.92E-15 T 01-11-2018 IPR010920 LSM domain superfamily MLA2C4_24610 5ccf1d2fd6f6e811bf360ca074f52d75 374 Pfam PF00561 alpha/beta hydrolase fold 41 248 1.5E-7 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_24610 5ccf1d2fd6f6e811bf360ca074f52d75 374 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 1 367 23.764 T 01-11-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MLA2C4_24610 5ccf1d2fd6f6e811bf360ca074f52d75 374 PIRSF PIRSF000443 2 374 3.0E-121 T 01-11-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MLA2C4_24610 5ccf1d2fd6f6e811bf360ca074f52d75 374 Gene3D G3DSA:3.40.50.1820 1 374 2.3E-121 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_24610 5ccf1d2fd6f6e811bf360ca074f52d75 374 SUPERFAMILY SSF53474 5 368 2.18E-67 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 SUPERFAMILY SSF81338 2 234 2.09E-73 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 230 2.6E-63 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 PRINTS PR00783 Major intrinsic protein family signature 44 68 3.6E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 PRINTS PR00783 Major intrinsic protein family signature 136 154 3.6E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 PRINTS PR00783 Major intrinsic protein family signature 213 233 3.6E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 PRINTS PR00783 Major intrinsic protein family signature 166 188 3.6E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 PRINTS PR00783 Major intrinsic protein family signature 2 21 3.6E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 PRINTS PR00783 Major intrinsic protein family signature 81 100 3.6E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 Gene3D G3DSA:1.20.1080.10 1 243 1.1E-75 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 ProSitePatterns PS00221 MIP family signature. 62 70 - T 01-11-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 MLA2C4_05505 a96cb9f355d4590b72372a3657fb81aa 273 Pfam PF00230 Major intrinsic protein 3 230 2.0E-47 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_19215 0b716132de312df22bf58bf9ae6165d4 180 Pfam PF08006 Protein of unknown function (DUF1700) 1 179 2.8E-74 T 01-11-2018 IPR012963 Protein of unknown function DUF1700 MLA2C4_14230 8358c699c9e29396ae8aaa1110ef7ee7 303 Pfam PF00892 EamA-like transporter family 152 284 3.6E-17 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_14230 8358c699c9e29396ae8aaa1110ef7ee7 303 Pfam PF00892 EamA-like transporter family 16 142 1.8E-28 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_14230 8358c699c9e29396ae8aaa1110ef7ee7 303 SUPERFAMILY SSF103481 188 286 6.54E-12 T 01-11-2018 MLA2C4_14230 8358c699c9e29396ae8aaa1110ef7ee7 303 SUPERFAMILY SSF103481 43 144 9.29E-18 T 01-11-2018 MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 10 22 2.8E-6 T 01-11-2018 IPR003004 GspF/PilC family MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 106 134 2.8E-6 T 01-11-2018 IPR003004 GspF/PilC family MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 324 343 2.8E-6 T 01-11-2018 IPR003004 GspF/PilC family MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 PRINTS PR00812 Bacterial general secretion pathway protein F signature 308 322 2.8E-6 T 01-11-2018 IPR003004 GspF/PilC family MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 Gene3D G3DSA:1.20.81.30 196 308 1.3E-13 T 01-11-2018 MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 Pfam PF00482 Type II secretion system (T2SS), protein F 213 335 1.9E-19 T 01-11-2018 IPR018076 Type II secretion system F domain MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 Pfam PF00482 Type II secretion system (T2SS), protein F 15 134 1.6E-13 T 01-11-2018 IPR018076 Type II secretion system F domain MLA2C4_22185 2be0ce87f8e58a52efcbed91c4a6b3fd 343 Gene3D G3DSA:1.20.81.30 2 114 1.2E-11 T 01-11-2018 MLA2C4_21320 add0fc872ff4c3ca4b76151b84b7bc4f 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 1.0E-45 T 01-11-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 MLA2C4_21320 add0fc872ff4c3ca4b76151b84b7bc4f 116 Pfam PF01740 STAS domain 5 107 1.4E-22 T 01-11-2018 IPR002645 STAS domain MLA2C4_21320 add0fc872ff4c3ca4b76151b84b7bc4f 116 SUPERFAMILY SSF52091 3 111 3.92E-31 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_21320 add0fc872ff4c3ca4b76151b84b7bc4f 116 Gene3D G3DSA:3.30.750.24 2 116 2.9E-33 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_21320 add0fc872ff4c3ca4b76151b84b7bc4f 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 106 1.2E-36 T 01-11-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MLA2C4_16685 ea55e5d0cbededd8d959df9d102aef2f 158 SMART SM01058 6 116 1.2E-30 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_16685 ea55e5d0cbededd8d959df9d102aef2f 158 Gene3D G3DSA:1.20.58.1290 67 158 9.7E-27 T 01-11-2018 MLA2C4_16685 ea55e5d0cbededd8d959df9d102aef2f 158 Pfam PF02559 CarD-like/TRCF domain 7 115 1.0E-17 T 01-11-2018 IPR003711 CarD-like/TRCF domain MLA2C4_16685 ea55e5d0cbededd8d959df9d102aef2f 158 Gene3D G3DSA:2.30.30.840 2 66 1.1E-25 T 01-11-2018 MLA2C4_16685 ea55e5d0cbededd8d959df9d102aef2f 158 SUPERFAMILY SSF141259 5 64 2.88E-12 T 01-11-2018 IPR036101 CarD-like/TRCF domain superfamily MLA2C4_15835 3cc628c81f816ad4222c1eddc6991eb1 199 Gene3D G3DSA:3.40.50.300 3 194 3.9E-47 T 01-11-2018 MLA2C4_15835 3cc628c81f816ad4222c1eddc6991eb1 199 SUPERFAMILY SSF52540 10 192 1.59E-22 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_15835 3cc628c81f816ad4222c1eddc6991eb1 199 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 19 154 3.9E-5 T 01-11-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MLA2C4_12905 e31b14caf500cd3019603adf82fb5163 176 Gene3D G3DSA:3.40.630.30 2 169 2.6E-49 T 01-11-2018 MLA2C4_12905 e31b14caf500cd3019603adf82fb5163 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 7.3E-33 T 01-11-2018 IPR000182 GNAT domain MLA2C4_12905 e31b14caf500cd3019603adf82fb5163 176 SUPERFAMILY SSF55729 3 173 9.91E-49 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_08840 26b885d87bf5b67e4989ff6bf2a134dd 330 SUPERFAMILY SSF52540 3 244 2.97E-82 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08840 26b885d87bf5b67e4989ff6bf2a134dd 330 Gene3D G3DSA:3.40.50.300 3 277 1.4E-70 T 01-11-2018 MLA2C4_08840 26b885d87bf5b67e4989ff6bf2a134dd 330 Pfam PF00005 ABC transporter 18 165 3.4E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_08840 26b885d87bf5b67e4989ff6bf2a134dd 330 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_08840 26b885d87bf5b67e4989ff6bf2a134dd 330 SMART SM00382 27 215 6.6E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_08840 26b885d87bf5b67e4989ff6bf2a134dd 330 SUPERFAMILY SSF50331 249 318 2.13E-6 T 01-11-2018 IPR008995 Molybdate/tungstate binding, C-terminal MLA2C4_27060 dea3217625184c301b50c6f7953a984a 642 PIRSF PIRSF005091 1 623 8.7E-176 T 01-11-2018 IPR012160 Lipoteichoic acid synthase-like MLA2C4_27060 dea3217625184c301b50c6f7953a984a 642 Gene3D G3DSA:3.40.720.10 241 548 4.8E-76 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_27060 dea3217625184c301b50c6f7953a984a 642 SUPERFAMILY SSF53649 246 619 3.92E-72 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_27060 dea3217625184c301b50c6f7953a984a 642 Pfam PF00884 Sulfatase 248 538 1.3E-37 T 01-11-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MLA2C4_05170 268a6ceb7e640b7ebda2e1f4c540092e 332 Gene3D G3DSA:3.40.50.10440 12 186 6.9E-53 T 01-11-2018 MLA2C4_05170 268a6ceb7e640b7ebda2e1f4c540092e 332 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 3 332 6.3E-132 T 01-11-2018 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b MLA2C4_05170 268a6ceb7e640b7ebda2e1f4c540092e 332 SUPERFAMILY SSF82549 1 332 4.97E-101 T 01-11-2018 MLA2C4_05170 268a6ceb7e640b7ebda2e1f4c540092e 332 Pfam PF02733 Dak1 domain 18 329 5.8E-94 T 01-11-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05170 268a6ceb7e640b7ebda2e1f4c540092e 332 Gene3D G3DSA:3.30.1180.20 187 332 1.5E-43 T 01-11-2018 MLA2C4_17880 65e5960f4334cf010d73831709333e63 159 SMART SM00871 2 157 1.1E-5 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_17880 65e5960f4334cf010d73831709333e63 159 Gene3D G3DSA:3.20.80.10 2 159 5.2E-15 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_17880 65e5960f4334cf010d73831709333e63 159 Pfam PF14526 Integron-associated effector binding protein 5 156 8.0E-30 T 01-11-2018 IPR029441 Integron-associated effector binding protein MLA2C4_04095 8d9f65f2f03c6c22bd7ab680aa27c4fa 369 Pfam PF03845 Spore germination protein 9 323 5.0E-81 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_04095 8d9f65f2f03c6c22bd7ab680aa27c4fa 369 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 357 2.9E-46 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_28430 9eab4035a144788ee7141987f91a78fd 198 SUPERFAMILY SSF53163 10 195 3.27E-54 T 01-11-2018 IPR023430 Peptidase HybD-like domain superfamily MLA2C4_28430 9eab4035a144788ee7141987f91a78fd 198 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 44 182 2.3E-69 T 01-11-2018 IPR009665 Protein of unknown function DUF1256 MLA2C4_28430 9eab4035a144788ee7141987f91a78fd 198 Pfam PF06866 Protein of unknown function (DUF1256) 19 180 1.5E-64 T 01-11-2018 IPR009665 Protein of unknown function DUF1256 MLA2C4_16030 f1a93d8b25fc73c076bf2c5873cb1d73 150 Pfam PF00293 NUDIX domain 22 127 8.5E-9 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_16030 f1a93d8b25fc73c076bf2c5873cb1d73 150 SUPERFAMILY SSF55811 7 143 6.91E-23 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_16030 f1a93d8b25fc73c076bf2c5873cb1d73 150 Gene3D G3DSA:3.90.79.10 3 145 5.3E-30 T 01-11-2018 MLA2C4_06265 cd7d3125e00b75ba6dc332fd96e5b951 227 Pfam PF05389 Negative regulator of genetic competence (MecA) 2 219 2.0E-48 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_06265 cd7d3125e00b75ba6dc332fd96e5b951 227 PIRSF PIRSF029008 1 225 5.5E-78 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_06265 cd7d3125e00b75ba6dc332fd96e5b951 227 Hamap MF_01124 Adapter protein MecA [mecA]. 1 223 27.417 T 01-11-2018 IPR008681 Negative regulator of genetic competence, MecA MLA2C4_06265 cd7d3125e00b75ba6dc332fd96e5b951 227 Gene3D G3DSA:3.30.70.1950 126 225 2.0E-30 T 01-11-2018 IPR038471 MecA, C-terminal domain superfamily MLA2C4_11215 5fb9821a003b8f5c18380125cfc3361a 239 Pfam PF01553 Acyltransferase 60 184 2.6E-32 T 01-11-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MLA2C4_11215 5fb9821a003b8f5c18380125cfc3361a 239 SUPERFAMILY SSF69593 46 237 1.24E-52 T 01-11-2018 MLA2C4_11215 5fb9821a003b8f5c18380125cfc3361a 239 SMART SM00563 74 188 8.8E-38 T 01-11-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MLA2C4_11215 5fb9821a003b8f5c18380125cfc3361a 239 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 59 185 1.7E-38 T 01-11-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 MLA2C4_26970 f874cec6435af3f80365064ccc8a3b39 105 Gene3D G3DSA:1.20.58.280 1 104 1.7E-41 T 01-11-2018 MLA2C4_26970 f874cec6435af3f80365064ccc8a3b39 105 PIRSF PIRSF000699 1 105 1.1E-39 T 01-11-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 MLA2C4_26970 f874cec6435af3f80365064ccc8a3b39 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 99 1.3E-39 T 01-11-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 MLA2C4_26970 f874cec6435af3f80365064ccc8a3b39 105 SUPERFAMILY SSF46973 2 100 2.22E-38 T 01-11-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 MLA2C4_26190 42928504aec470eea0a43598ecf3ef54 204 Pfam PF09335 SNARE associated Golgi protein 29 154 6.8E-18 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 Gene3D G3DSA:1.10.260.40 1 70 8.0E-20 T 01-11-2018 MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 SUPERFAMILY SSF51182 57 181 9.35E-25 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 Pfam PF07883 Cupin domain 106 174 2.3E-15 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 SUPERFAMILY SSF47413 3 72 8.04E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 Gene3D G3DSA:2.60.120.10 71 176 2.0E-18 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 SMART SM00530 9 64 4.6E-15 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_09040 4e98a7be1a5ebdd2342594ebd2c9c248 181 Pfam PF01381 Helix-turn-helix 10 61 2.6E-18 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 Pfam PF00005 ABC transporter 444 589 1.5E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 SUPERFAMILY SSF52540 421 660 6.3E-80 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 SMART SM00382 453 641 1.3E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 Gene3D G3DSA:3.40.50.300 424 666 5.0E-83 T 01-11-2018 MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 Pfam PF00664 ABC transporter transmembrane region 150 384 1.3E-40 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 Gene3D G3DSA:1.20.1560.10 126 412 1.8E-71 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_04650 dccbc8e337504e78917e65358f3d82c3 666 SUPERFAMILY SSF90123 5 414 3.4E-72 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 463 479 3.7E-30 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 500 518 3.7E-30 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 446 460 3.7E-30 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 526 541 3.7E-30 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 160 178 3.7E-30 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 SUPERFAMILY SSF49299 733 850 2.09E-17 T 01-11-2018 IPR035986 PKD domain superfamily MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Gene3D G3DSA:3.30.980.50 655 764 5.5E-47 T 01-11-2018 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Pfam PF01752 Collagenase 310 624 2.1E-81 T 01-11-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004222|GO:0005576|GO:0006508|GO:0008270 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Pfam PF00801 PKD domain 793 840 5.6E-10 T 01-11-2018 IPR000601 PKD domain MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Gene3D G3DSA:2.60.40.10 765 851 1.0E-23 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 SUPERFAMILY SSF89260 855 964 1.57E-30 T 01-11-2018 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Gene3D G3DSA:1.10.1740.190 373 516 1.3E-59 T 01-11-2018 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Gene3D G3DSA:1.10.390.20 517 654 1.4E-54 T 01-11-2018 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Gene3D G3DSA:2.60.120.380 852 965 1.4E-24 T 01-11-2018 MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 SMART SM00089 771 853 3.0E-15 T 01-11-2018 IPR022409 PKD/Chitinase domain MLA2C4_02975 763307248d1242ccd269bb659213e1a8 965 Pfam PF08453 Peptidase family M9 N-terminal 94 275 9.7E-52 T 01-11-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain MLA2C4_22860 541eefcea9bf4740a158dc2a7c6d9621 309 Pfam PF01136 Peptidase family U32 75 306 2.3E-71 T 01-11-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MLA2C4_15985 1b16cac953430b7b92f9ad4ab4f8519e 129 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.3E-12 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_15985 1b16cac953430b7b92f9ad4ab4f8519e 129 SUPERFAMILY SSF46785 7 84 2.35E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_15985 1b16cac953430b7b92f9ad4ab4f8519e 129 SMART SM00345 17 76 6.6E-11 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_15985 1b16cac953430b7b92f9ad4ab4f8519e 129 Gene3D G3DSA:1.10.10.10 10 129 2.1E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08220 3a47b1dabc8483470b72b958279c2b4c 157 SUPERFAMILY SSF55729 1 150 5.85E-24 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_08220 3a47b1dabc8483470b72b958279c2b4c 157 Gene3D G3DSA:3.40.630.30 4 155 9.7E-22 T 01-11-2018 MLA2C4_08220 3a47b1dabc8483470b72b958279c2b4c 157 Pfam PF00583 Acetyltransferase (GNAT) family 32 130 3.2E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_26625 069d1d8afc1f7035849a70d2136cd51f 338 PIRSF PIRSF011570 1 335 3.5E-158 T 01-11-2018 IPR010894 Stage V sporulation AD MLA2C4_26625 069d1d8afc1f7035849a70d2136cd51f 338 SUPERFAMILY SSF53901 56 308 2.0E-16 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_26625 069d1d8afc1f7035849a70d2136cd51f 338 Gene3D G3DSA:3.40.47.40 1 338 4.0E-148 T 01-11-2018 IPR038369 Stage V sporulation AD superfamily MLA2C4_26625 069d1d8afc1f7035849a70d2136cd51f 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 3.3E-156 T 01-11-2018 IPR010894 Stage V sporulation AD MLA2C4_26625 069d1d8afc1f7035849a70d2136cd51f 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 2.3E-160 T 01-11-2018 IPR010894 Stage V sporulation AD MLA2C4_12630 5d6fcc397673a862de322fe2fafa9a60 72 SUPERFAMILY SSF47413 2 68 9.38E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_12630 5d6fcc397673a862de322fe2fafa9a60 72 Gene3D G3DSA:1.10.260.40 2 66 5.7E-14 T 01-11-2018 MLA2C4_12630 5d6fcc397673a862de322fe2fafa9a60 72 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 66 9.8E-8 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12630 5d6fcc397673a862de322fe2fafa9a60 72 SMART SM00530 7 62 6.5E-5 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_01105 997dd3250466f3891225ec286b3be55e 155 Pfam PF14039 YusW-like protein 51 144 4.5E-27 T 01-11-2018 IPR025623 YusW-like protein MLA2C4_25760 f3ad9d5601c9a2efcaf3bdf4acab4e1c 78 Pfam PF01106 NifU-like domain 11 75 5.0E-28 T 01-11-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MLA2C4_25760 f3ad9d5601c9a2efcaf3bdf4acab4e1c 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 77 4.0E-29 T 01-11-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MLA2C4_25760 f3ad9d5601c9a2efcaf3bdf4acab4e1c 78 Gene3D G3DSA:3.30.300.130 1 78 6.0E-33 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_25760 f3ad9d5601c9a2efcaf3bdf4acab4e1c 78 SUPERFAMILY SSF117916 2 77 2.13E-26 T 01-11-2018 IPR034904 Fe-S cluster assembly domain superfamily MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 8.0E-43 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 8.0E-43 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 8.0E-43 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 8.0E-43 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 8.0E-43 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 8.0E-43 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 SUPERFAMILY SSF52096 3 311 8.42E-94 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 311 2.7E-146 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 145 4.4E-63 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 2 313 47.589 T 01-11-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MLA2C4_16795 53fa0e19f33a4dbf81110e8cd72c938e 314 Gene3D G3DSA:3.90.226.10 1 314 1.2E-115 T 01-11-2018 MLA2C4_01235 303b307c1d1a76fe8c809304c7e52a8f 549 SUPERFAMILY SSF88713 227 402 3.06E-7 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_01235 303b307c1d1a76fe8c809304c7e52a8f 549 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 213 474 6.5E-69 T 01-11-2018 IPR018763 Protein of unknown function DUF2334 MLA2C4_01235 303b307c1d1a76fe8c809304c7e52a8f 549 Gene3D G3DSA:3.20.20.370 196 497 1.7E-5 T 01-11-2018 MLA2C4_18220 e369915cfd567df3d25268e916065208 202 SUPERFAMILY SSF50475 10 180 3.6E-36 T 01-11-2018 MLA2C4_18220 e369915cfd567df3d25268e916065208 202 Pfam PF04299 Putative FMN-binding domain 1 158 5.2E-53 T 01-11-2018 IPR007396 Transcriptional regulator PAI 2-type MLA2C4_18220 e369915cfd567df3d25268e916065208 202 PIRSF PIRSF010372 1 201 8.5E-64 T 01-11-2018 IPR007396 Transcriptional regulator PAI 2-type MLA2C4_18220 e369915cfd567df3d25268e916065208 202 Gene3D G3DSA:2.30.110.10 1 201 4.2E-74 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 MLA2C4_25645 9cbbf41e026c29132ad22fd3c7af567c 159 SUPERFAMILY SSF55136 6 158 5.58E-24 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_25645 9cbbf41e026c29132ad22fd3c7af567c 159 SMART SM00871 3 159 2.9E-36 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_25645 9cbbf41e026c29132ad22fd3c7af567c 159 Pfam PF14526 Integron-associated effector binding protein 7 157 1.1E-29 T 01-11-2018 IPR029441 Integron-associated effector binding protein MLA2C4_25645 9cbbf41e026c29132ad22fd3c7af567c 159 Gene3D G3DSA:3.20.80.10 1 158 7.1E-45 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_12745 3850456eeb773a798fc09a4c810b4599 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 9.5E-17 T 01-11-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MLA2C4_12745 3850456eeb773a798fc09a4c810b4599 101 SUPERFAMILY SSF52794 1 100 1.18E-27 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_12745 3850456eeb773a798fc09a4c810b4599 101 Gene3D G3DSA:3.40.50.2300 1 101 4.2E-30 T 01-11-2018 MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 SMART SM00967 42 110 2.3E-8 T 01-11-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 Gene3D G3DSA:3.40.1280.10 107 264 4.7E-53 T 01-11-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 SUPERFAMILY SSF55315 14 107 1.06E-23 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 Gene3D G3DSA:3.30.1330.30 13 106 4.6E-23 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 Pfam PF00588 SpoU rRNA Methylase family 119 256 1.8E-37 T 01-11-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 SUPERFAMILY SSF75217 116 259 1.41E-43 T 01-11-2018 IPR029028 Alpha/beta knot methyltransferases MLA2C4_23705 7b9a72ed9f693e6b63a07477d8923f6d 265 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 42 108 4.7E-10 T 01-11-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MLA2C4_27900 7adfece416295ee8ceda8a28a82e33ab 131 SUPERFAMILY SSF46689 19 124 8.24E-5 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 Pfam PF00232 Glycosyl hydrolase family 1 4 474 3.6E-141 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 SUPERFAMILY SSF51445 5 475 4.83E-164 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 9.8E-17 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 319 9.8E-17 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 9.8E-17 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 9.8E-17 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 9.8E-17 T 01-11-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 Gene3D G3DSA:3.20.20.80 2 477 6.7E-159 T 01-11-2018 MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 01-11-2018 IPR018120 Glycoside hydrolase family 1, active site MLA2C4_05110 bd7d7036c5722d5fece98039d88683cd 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 01-11-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site MLA2C4_04005 febcba9e04a5ba5833e9f74dfbd7e1fc 381 SUPERFAMILY SSF52402 251 369 4.33E-15 T 01-11-2018 MLA2C4_04005 febcba9e04a5ba5833e9f74dfbd7e1fc 381 Gene3D G3DSA:3.40.50.620 236 376 4.0E-11 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_04005 febcba9e04a5ba5833e9f74dfbd7e1fc 381 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 27 234 2.7E-89 T 01-11-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 MLA2C4_04005 febcba9e04a5ba5833e9f74dfbd7e1fc 381 Pfam PF00582 Universal stress protein family 251 369 9.1E-11 T 01-11-2018 IPR006016 UspA MLA2C4_04005 febcba9e04a5ba5833e9f74dfbd7e1fc 381 Gene3D G3DSA:3.40.50.300 24 234 1.8E-88 T 01-11-2018 MLA2C4_06360 32db997f030b7287651aa3b9ff10f85a 229 Gene3D G3DSA:3.40.50.150 19 229 2.2E-65 T 01-11-2018 MLA2C4_06360 32db997f030b7287651aa3b9ff10f85a 229 Pfam PF13489 Methyltransferase domain 29 178 1.5E-17 T 01-11-2018 MLA2C4_06360 32db997f030b7287651aa3b9ff10f85a 229 SUPERFAMILY SSF53335 16 194 1.02E-35 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_17140 607bbdb6ef0867080a4646ca281c63bc 69 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_17140 607bbdb6ef0867080a4646ca281c63bc 69 Gene3D G3DSA:1.10.8.910 15 69 1.3E-24 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_17140 607bbdb6ef0867080a4646ca281c63bc 69 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 18 62 1.9E-15 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 SUPERFAMILY SSF55874 252 371 1.83E-16 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 Pfam PF13185 GAF domain 24 168 8.7E-15 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 Pfam PF07730 Histidine kinase 184 248 1.3E-14 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 SUPERFAMILY SSF55781 26 178 2.84E-20 T 01-11-2018 MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 SMART SM00065 26 177 1.0E-4 T 01-11-2018 IPR003018 GAF domain GO:0005515 MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 Gene3D G3DSA:3.30.565.10 243 372 6.1E-26 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 Gene3D G3DSA:3.30.450.40 9 178 5.1E-23 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_11315 5a2e25e67413d7f79b22e9c67846f2ec 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 371 3.3E-7 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_13090 8e74aada3f936ace63829d0c456f98f6 78 Pfam PF10779 Haemolysin XhlA 6 72 1.3E-15 T 01-11-2018 IPR019715 Haemolysin XhlA MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 SUPERFAMILY SSF48557 7 464 3.61E-148 T 01-11-2018 IPR008948 L-Aspartase-like GO:0003824 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 Pfam PF00206 Lyase 15 344 7.9E-111 T 01-11-2018 IPR022761 Fumarate lyase, N-terminal MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 Gene3D G3DSA:1.20.200.10 142 409 9.7E-114 T 01-11-2018 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 8 468 4.3E-238 T 01-11-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 7.5E-6 T 01-11-2018 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 7.5E-6 T 01-11-2018 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 Gene3D G3DSA:1.10.40.30 410 461 7.4E-24 T 01-11-2018 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 1.2E-31 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 1.2E-31 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 1.2E-31 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 1.2E-31 T 01-11-2018 IPR000362 Fumarate lyase family MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 Pfam PF10415 Fumarase C C-terminus 410 463 7.7E-23 T 01-11-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 01-11-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MLA2C4_03215 71aecba8bf3ddf4e6ab8afcb4c84ec1c 477 Gene3D G3DSA:1.10.275.10 8 141 3.5E-58 T 01-11-2018 IPR024083 Fumarase/histidase, N-terminal MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 Gene3D G3DSA:1.20.1480.50 177 263 5.1E-14 T 01-11-2018 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 334 3.7E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 Gene3D G3DSA:3.30.565.10 341 495 3.4E-47 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 SMART SM00388 269 336 2.3E-14 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 SUPERFAMILY SSF47384 256 334 3.92E-17 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 SMART SM00304 209 261 1.3E-15 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 Pfam PF00672 HAMP domain 209 257 7.2E-12 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 SMART SM00387 383 496 3.9E-35 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 474 1.1E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 449 1.1E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 435 1.1E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 493 1.1E-16 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 SUPERFAMILY SSF55874 325 492 3.8E-43 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 383 493 5.0E-27 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 Gene3D G3DSA:1.10.287.130 264 338 1.3E-18 T 01-11-2018 MLA2C4_09425 9d2b929a3adf7824e12549527a765443 496 SUPERFAMILY SSF158472 209 260 1.44E-10 T 01-11-2018 MLA2C4_04520 521b7237f03456fa1a1ba3ec8f9d4ab9 134 Pfam PF07681 DoxX 7 85 4.9E-19 T 01-11-2018 IPR032808 DoxX family MLA2C4_23320 f3956014536622761e797c78c991f8fc 332 Gene3D G3DSA:1.25.40.10 14 251 3.2E-8 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_23320 f3956014536622761e797c78c991f8fc 332 SUPERFAMILY SSF48452 15 212 1.25E-7 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_05640 18c9bc4f11c7c37cebea7b29c3f2ca71 417 Gene3D G3DSA:3.40.50.1820 4 273 1.9E-14 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_05640 18c9bc4f11c7c37cebea7b29c3f2ca71 417 Pfam PF01764 Lipase (class 3) 147 190 3.6E-6 T 01-11-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 MLA2C4_05640 18c9bc4f11c7c37cebea7b29c3f2ca71 417 SUPERFAMILY SSF53474 11 243 3.09E-24 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 SUPERFAMILY SSF48256 7 368 3.93E-121 T 01-11-2018 IPR036969 Citrate synthase superfamily GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 Pfam PF00285 Citrate synthase, C-terminal domain 11 361 1.7E-113 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 ProSitePatterns PS00480 Citrate synthase signature. 260 273 - T 01-11-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 Gene3D G3DSA:1.10.230.10 226 325 5.9E-112 T 01-11-2018 IPR016143 Citrate synthase-like, small alpha subdomain MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PIRSF PIRSF001369 2 372 2.9E-139 T 01-11-2018 IPR024176 Citrate synthase, bacterial-type MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PRINTS PR00143 Citrate synthase signature 129 142 3.3E-34 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PRINTS PR00143 Citrate synthase signature 311 327 3.3E-34 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PRINTS PR00143 Citrate synthase signature 331 345 3.3E-34 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PRINTS PR00143 Citrate synthase signature 178 193 3.3E-34 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PRINTS PR00143 Citrate synthase signature 200 228 3.3E-34 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 PRINTS PR00143 Citrate synthase signature 253 273 3.3E-34 T 01-11-2018 IPR002020 Citrate synthase GO:0046912 MLA2C4_12110 ce5664fa1a814954e7b9a4100e6f3b01 373 Gene3D G3DSA:1.10.580.10 34 357 5.9E-112 T 01-11-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MLA2C4_17500 91a84ba1585613d4f13eb0ede0112bd1 141 Pfam PF07853 Protein of unknown function (DUF1648) 1 47 1.1E-17 T 01-11-2018 IPR012867 Domain of unknown function DUF1648 MLA2C4_15820 5b4f400d0c4662394a09f03d9175feef 438 SUPERFAMILY SSF55874 300 416 8.17E-9 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_15820 5b4f400d0c4662394a09f03d9175feef 438 Gene3D G3DSA:3.30.565.10 286 435 6.1E-20 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_15820 5b4f400d0c4662394a09f03d9175feef 438 Pfam PF14501 GHKL domain 334 434 1.2E-11 T 01-11-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain MLA2C4_28170 4268141fdb36305bc309317d8a3b4d1e 230 Pfam PF04172 LrgB-like family 14 227 5.1E-69 T 01-11-2018 IPR007300 CidB/LrgB family MLA2C4_28170 4268141fdb36305bc309317d8a3b4d1e 230 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 230 35.072 T 01-11-2018 IPR024891 Antiholin-like protein LrgB MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 227 382 3.9E-38 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 Pfam PF00672 HAMP domain 74 121 3.2E-11 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 Gene3D G3DSA:1.10.287.950 127 429 6.9E-60 T 01-11-2018 MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 SUPERFAMILY SSF58104 101 428 1.7E-63 T 01-11-2018 MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 SMART SM00283 154 429 1.2E-52 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 Gene3D G3DSA:1.20.1480.50 42 126 3.5E-10 T 01-11-2018 MLA2C4_02180 48dc73960718d25690db5fdac001156f 430 SMART SM00304 72 125 4.3E-10 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 SUPERFAMILY SSF81338 2 219 3.66E-57 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 Pfam PF00230 Major intrinsic protein 2 212 6.8E-47 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 PRINTS PR00783 Major intrinsic protein family signature 3 22 3.0E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 PRINTS PR00783 Major intrinsic protein family signature 78 97 3.0E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 PRINTS PR00783 Major intrinsic protein family signature 157 179 3.0E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 PRINTS PR00783 Major intrinsic protein family signature 41 65 3.0E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 PRINTS PR00783 Major intrinsic protein family signature 127 145 3.0E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 PRINTS PR00783 Major intrinsic protein family signature 196 216 3.0E-52 T 01-11-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 Gene3D G3DSA:1.20.1080.10 1 219 7.0E-64 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_23435 6a21a5be2a652d1ed4cad7234b820fef 221 ProSitePatterns PS00221 MIP family signature. 59 67 - T 01-11-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 MLA2C4_20860 7f35be1a5d4476202353a6315607026e 286 SUPERFAMILY SSF56300 56 283 4.56E-37 T 01-11-2018 MLA2C4_20860 7f35be1a5d4476202353a6315607026e 286 Pfam PF00149 Calcineurin-like phosphoesterase 58 223 2.5E-12 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_20860 7f35be1a5d4476202353a6315607026e 286 Gene3D G3DSA:3.60.21.10 56 253 1.5E-26 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_18280 71ed43ce76bee996b1a6c97c24edbd92 97 Gene3D G3DSA:1.10.10.10 3 96 8.0E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18280 71ed43ce76bee996b1a6c97c24edbd92 97 Pfam PF01022 Bacterial regulatory protein, arsR family 26 66 8.2E-13 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18280 71ed43ce76bee996b1a6c97c24edbd92 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 4.1E-5 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18280 71ed43ce76bee996b1a6c97c24edbd92 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 4.1E-5 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_18280 71ed43ce76bee996b1a6c97c24edbd92 97 SUPERFAMILY SSF46785 15 95 1.21E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_18280 71ed43ce76bee996b1a6c97c24edbd92 97 SMART SM00418 19 97 3.7E-21 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_02655 228229e9e974131df62565d7625db5ae 388 SUPERFAMILY SSF53756 6 366 1.51E-34 T 01-11-2018 MLA2C4_02655 228229e9e974131df62565d7625db5ae 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 229 348 7.0E-13 T 01-11-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MLA2C4_02655 228229e9e974131df62565d7625db5ae 388 Gene3D G3DSA:3.40.50.2000 191 352 1.2E-29 T 01-11-2018 MLA2C4_02655 228229e9e974131df62565d7625db5ae 388 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 179 3.5E-40 T 01-11-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 MLA2C4_02655 228229e9e974131df62565d7625db5ae 388 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 1 388 58.263 T 01-11-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-7817 MLA2C4_14335 84f8f768544ed29feaad3d03975c1310 125 SUPERFAMILY SSF50729 6 124 1.6E-44 T 01-11-2018 MLA2C4_14335 84f8f768544ed29feaad3d03975c1310 125 Pfam PF08000 Bacterial PH domain 3 122 2.9E-48 T 01-11-2018 IPR012544 Bacterial Pleckstrin homology domain MLA2C4_14335 84f8f768544ed29feaad3d03975c1310 125 Gene3D G3DSA:2.30.29.50 1 124 5.5E-50 T 01-11-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily MLA2C4_28150 b295efafbb27601ea8051caebc493788 290 Gene3D G3DSA:1.10.357.10 1 160 2.6E-29 T 01-11-2018 MLA2C4_28150 b295efafbb27601ea8051caebc493788 290 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 01-11-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MLA2C4_28150 b295efafbb27601ea8051caebc493788 290 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 7.2E-10 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_28150 b295efafbb27601ea8051caebc493788 290 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 7.2E-10 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_28150 b295efafbb27601ea8051caebc493788 290 SUPERFAMILY SSF46689 3 69 6.16E-19 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_28150 b295efafbb27601ea8051caebc493788 290 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 6.6E-18 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_22835 bc3e5acd4d7ab34d343d030f922dd4f4 215 Pfam PF07423 Protein of unknown function (DUF1510) 5 214 1.8E-73 T 01-11-2018 IPR009988 Protein of unknown function DUF1510 MLA2C4_05945 7e801f99c3970e60221d94ad911bbb92 263 Pfam PF01636 Phosphotransferase enzyme family 121 181 6.4E-11 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_05945 7e801f99c3970e60221d94ad911bbb92 263 SUPERFAMILY SSF56112 9 259 4.68E-27 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_05945 7e801f99c3970e60221d94ad911bbb92 263 Gene3D G3DSA:3.90.1200.10 62 248 3.3E-9 T 01-11-2018 MLA2C4_20545 a20ad02cf7b9a206a8f6854e7fe8ae5b 88 Hamap MF_01126 UPF0298 protein . 1 78 23.278 T 01-11-2018 IPR016979 Protein of unknown function DUF2129 MLA2C4_20545 a20ad02cf7b9a206a8f6854e7fe8ae5b 88 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 7.5E-30 T 01-11-2018 IPR016979 Protein of unknown function DUF2129 MLA2C4_20545 a20ad02cf7b9a206a8f6854e7fe8ae5b 88 PIRSF PIRSF031653 1 88 1.9E-34 T 01-11-2018 IPR016979 Protein of unknown function DUF2129 MLA2C4_16110 34bca35839881483230bb6e51fec03c9 256 SUPERFAMILY SSF48371 7 246 1.84E-43 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_16110 34bca35839881483230bb6e51fec03c9 256 Gene3D G3DSA:1.25.40.290 126 245 2.3E-30 T 01-11-2018 MLA2C4_16110 34bca35839881483230bb6e51fec03c9 256 Pfam PF08713 DNA alkylation repair enzyme 12 228 9.6E-11 T 01-11-2018 IPR014825 DNA alkylation repair enzyme MLA2C4_22635 8d5d0a1d2f6139fbbf5bc3107abb4b18 368 Gene3D G3DSA:3.40.50.300 56 225 4.5E-53 T 01-11-2018 MLA2C4_22635 8d5d0a1d2f6139fbbf5bc3107abb4b18 368 SUPERFAMILY SSF52540 68 281 1.65E-30 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22635 8d5d0a1d2f6139fbbf5bc3107abb4b18 368 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 368 8.5E-158 T 01-11-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH MLA2C4_22635 8d5d0a1d2f6139fbbf5bc3107abb4b18 368 Pfam PF01926 50S ribosome-binding GTPase 163 237 1.1E-13 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_25280 14dc6b74c5cbc014a7bae970f52a6adf 317 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 21 311 19.7 T 01-11-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MLA2C4_25280 14dc6b74c5cbc014a7bae970f52a6adf 317 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 30 308 1.1E-38 T 01-11-2018 MLA2C4_25280 14dc6b74c5cbc014a7bae970f52a6adf 317 PIRSF PIRSF005355 14 316 2.1E-87 T 01-11-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 MLA2C4_25280 14dc6b74c5cbc014a7bae970f52a6adf 317 Pfam PF01040 UbiA prenyltransferase family 38 271 3.2E-35 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MLA2C4_19985 e6c276e832d7e3699d89ecf41294f713 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 01-11-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 MLA2C4_19985 e6c276e832d7e3699d89ecf41294f713 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 256 4.3E-88 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MLA2C4_19985 e6c276e832d7e3699d89ecf41294f713 258 SUPERFAMILY SSF64005 25 251 7.46E-91 T 01-11-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MLA2C4_19985 e6c276e832d7e3699d89ecf41294f713 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 257 40.816 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MLA2C4_19985 e6c276e832d7e3699d89ecf41294f713 258 Gene3D G3DSA:3.40.1180.10 11 258 1.4E-101 T 01-11-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MLA2C4_19985 e6c276e832d7e3699d89ecf41294f713 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 256 3.1E-86 T 01-11-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 SUPERFAMILY SSF56024 41 210 1.41E-39 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 PIRSF PIRSF000850 289 370 0.59 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 PIRSF PIRSF000850 224 292 5.4E-5 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 PIRSF PIRSF000850 27 118 0.0048 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 SUPERFAMILY SSF56024 191 379 2.92E-39 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 Gene3D G3DSA:3.30.870.10 218 393 1.7E-33 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 Gene3D G3DSA:3.30.870.10 40 217 9.5E-40 T 01-11-2018 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 SMART SM00155 307 334 1.4E-4 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 SMART SM00155 138 165 0.042 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 Pfam PF13091 PLD-like domain 56 196 1.5E-11 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 Pfam PF13091 PLD-like domain 237 355 2.9E-27 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_10400 f4d8a56d1b215890ab0420a734588edd 394 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 28 391 8.8E-95 T 01-11-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MLA2C4_26255 095e216eaace67d5c8ceb744ab6233ea 232 Gene3D G3DSA:2.60.120.10 9 229 5.8E-80 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_26255 095e216eaace67d5c8ceb744ab6233ea 232 SUPERFAMILY SSF51182 5 229 6.08E-69 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_26255 095e216eaace67d5c8ceb744ab6233ea 232 PIRSF PIRSF006232 1 230 4.9E-58 T 01-11-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MLA2C4_26255 095e216eaace67d5c8ceb744ab6233ea 232 Pfam PF02678 Pirin 12 118 2.2E-33 T 01-11-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MLA2C4_26255 095e216eaace67d5c8ceb744ab6233ea 232 Gene3D G3DSA:2.60.120.10 11 134 5.8E-80 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_13395 a47143807c4642b27f406f2555550976 499 PIRSF PIRSF005690 5 485 4.6E-143 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_13395 a47143807c4642b27f406f2555550976 499 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 17 470 9.4E-156 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PIRSF PIRSF006615 4 505 9.9E-200 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 SUPERFAMILY SSF55486 7 499 3.77E-123 T 01-11-2018 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 2 499 6.2E-219 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 406 427 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 152 172 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 451 469 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 383 400 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 337 356 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 2.1E-81 T 01-11-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 MLA2C4_08215 d0321904054093601db198a3017e23ce 505 Gene3D G3DSA:1.10.1370.30 3 505 6.4E-211 T 01-11-2018 MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 Pfam PF01047 MarR family 40 97 5.7E-19 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 SMART SM00347 33 133 8.9E-30 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.9E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.9E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.9E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 SUPERFAMILY SSF46785 8 145 1.08E-34 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_07085 7ee8996c71392620535f68f4d6fbaee1 148 Gene3D G3DSA:1.10.10.10 1 147 2.4E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 SUPERFAMILY SSF51905 3 207 1.3E-26 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 5.8E-6 T 01-11-2018 MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.8E-6 T 01-11-2018 MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 5.8E-6 T 01-11-2018 MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 Gene3D G3DSA:3.50.50.100 1 402 4.8E-133 T 01-11-2018 MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 SUPERFAMILY SSF51905 150 331 1.03E-21 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_25635 807715dd5b1fc7c71143adba38114953 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 322 1.9E-44 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_02485 2cbdd362a92e1aa61c53091730b700ba 198 Pfam PF09335 SNARE associated Golgi protein 30 156 3.1E-19 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_12780 7f7b2e76bd93be07cbbe72a2124cf3be 333 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 01-11-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MLA2C4_12780 7f7b2e76bd93be07cbbe72a2124cf3be 333 Gene3D G3DSA:3.40.50.1100 56 152 2.5E-125 T 01-11-2018 MLA2C4_12780 7f7b2e76bd93be07cbbe72a2124cf3be 333 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 311 5.5E-81 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_12780 7f7b2e76bd93be07cbbe72a2124cf3be 333 Gene3D G3DSA:3.40.50.1100 13 316 2.5E-125 T 01-11-2018 MLA2C4_12780 7f7b2e76bd93be07cbbe72a2124cf3be 333 SUPERFAMILY SSF53686 9 319 4.32E-98 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_12780 7f7b2e76bd93be07cbbe72a2124cf3be 333 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 27 325 3.7E-121 T 01-11-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MLA2C4_04955 6c0381666557f63c989af5d12756b7f0 814 Pfam PF04411 PD-(D/E)XK nuclease superfamily 391 545 1.6E-49 T 01-11-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 MLA2C4_04955 6c0381666557f63c989af5d12756b7f0 814 Pfam PF09823 Domain of unknown function (DUF2357) 124 368 4.4E-84 T 01-11-2018 IPR018633 Domain of unknown function DUF2357 MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Gene3D G3DSA:2.30.30.40 111 163 5.1E-16 T 01-11-2018 MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Gene3D G3DSA:2.30.30.40 176 234 5.0E-17 T 01-11-2018 MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Pfam PF08239 Bacterial SH3 domain 48 94 6.8E-9 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Pfam PF08239 Bacterial SH3 domain 189 237 4.2E-13 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Pfam PF08239 Bacterial SH3 domain 114 164 5.2E-15 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 SUPERFAMILY SSF51261 199 384 4.5E-41 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Gene3D G3DSA:2.70.70.10 235 386 3.8E-37 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 SMART SM00287 104 167 6.0E-13 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 SMART SM00287 38 99 0.019 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 SMART SM00287 179 241 2.6E-9 T 01-11-2018 IPR003646 SH3-like domain, bacterial-type MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Gene3D G3DSA:2.30.30.500 46 110 1.2E-17 T 01-11-2018 MLA2C4_03915 ba38341f49e390806ffa109ed241cf11 386 Pfam PF01551 Peptidase family M23 277 374 2.1E-28 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 SUPERFAMILY SSF158472 185 232 4.32E-7 T 01-11-2018 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 3.6E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 3.6E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 3.6E-15 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 Pfam PF00672 HAMP domain 184 231 1.3E-6 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 453 1.6E-24 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 Gene3D G3DSA:3.30.565.10 301 453 2.3E-42 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 SUPERFAMILY SSF47384 219 304 1.37E-22 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 302 3.1E-17 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 SMART SM00388 236 303 2.3E-19 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 SMART SM00304 183 235 1.3E-9 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 Gene3D G3DSA:1.10.8.500 182 231 8.2E-6 T 01-11-2018 MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 SMART SM00387 347 453 7.0E-29 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 SUPERFAMILY SSF55874 293 453 1.57E-43 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_10050 a549b77b22d4ec9d8b34cf247295fc2d 453 Gene3D G3DSA:1.10.287.130 232 300 6.1E-22 T 01-11-2018 MLA2C4_11675 0a4f9157e574872c8054962c14857a9d 194 SUPERFAMILY SSF101386 2 194 1.05E-33 T 01-11-2018 MLA2C4_11675 0a4f9157e574872c8054962c14857a9d 194 Pfam PF08761 dUTPase 2 57 7.9E-11 T 01-11-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 MLA2C4_11675 0a4f9157e574872c8054962c14857a9d 194 Pfam PF08761 dUTPase 74 194 6.6E-20 T 01-11-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 MLA2C4_11675 0a4f9157e574872c8054962c14857a9d 194 Gene3D G3DSA:1.10.4010.10 70 194 7.2E-7 T 01-11-2018 MLA2C4_11675 0a4f9157e574872c8054962c14857a9d 194 PIRSF PIRSF030140 1 194 4.0E-40 T 01-11-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 MLA2C4_04390 555f26a90faa204c287d09222f5ce1b4 368 Gene3D G3DSA:2.40.420.20 283 367 7.4E-13 T 01-11-2018 MLA2C4_04390 555f26a90faa204c287d09222f5ce1b4 368 Pfam PF13437 HlyD family secretion protein 183 281 1.5E-7 T 01-11-2018 MLA2C4_04390 555f26a90faa204c287d09222f5ce1b4 368 Gene3D G3DSA:1.10.287.470 96 169 1.4E-17 T 01-11-2018 MLA2C4_04390 555f26a90faa204c287d09222f5ce1b4 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 367 7.1E-33 T 01-11-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MLA2C4_04390 555f26a90faa204c287d09222f5ce1b4 368 Gene3D G3DSA:2.40.50.100 76 211 1.4E-17 T 01-11-2018 MLA2C4_04390 555f26a90faa204c287d09222f5ce1b4 368 Gene3D G3DSA:2.40.30.170 212 281 1.4E-17 T 01-11-2018 MLA2C4_06195 c5472fadf49ebc43654edfc1fb369b8f 248 Pfam PF12227 Protein of unknown function (DUF3603) 35 248 6.7E-113 T 01-11-2018 IPR020909 UPF0736 MLA2C4_06195 c5472fadf49ebc43654edfc1fb369b8f 248 Hamap MF_01860 UPF0736 protein . 1 248 51.583 T 01-11-2018 IPR020909 UPF0736 MLA2C4_17270 29e76f1766ecddd3f5df92d5aad53e0f 79 Pfam PF13396 Phospholipase_D-nuclease N-terminal 32 73 2.9E-11 T 01-11-2018 IPR027379 Cardiolipin synthase N-terminal MLA2C4_05450 5b1c7429829f8c719d52f13e3c652343 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 271 5.2E-11 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_05450 5b1c7429829f8c719d52f13e3c652343 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 127 1.4E-7 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_05450 5b1c7429829f8c719d52f13e3c652343 314 Gene3D G3DSA:3.10.180.10 66 215 7.5E-129 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_05450 5b1c7429829f8c719d52f13e3c652343 314 SUPERFAMILY SSF54593 2 297 4.55E-47 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_05450 5b1c7429829f8c719d52f13e3c652343 314 Gene3D G3DSA:3.10.180.10 5 310 7.5E-129 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_06950 cc68102ce61c6cf42b5e398c7592c228 283 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 160 170 - T 01-11-2018 IPR024002 Formate/nitrite transporter, conserved site MLA2C4_06950 cc68102ce61c6cf42b5e398c7592c228 283 Gene3D G3DSA:1.20.1080.10 2 263 6.5E-83 T 01-11-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MLA2C4_06950 cc68102ce61c6cf42b5e398c7592c228 283 Pfam PF01226 Formate/nitrite transporter 10 251 1.4E-67 T 01-11-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_06950 cc68102ce61c6cf42b5e398c7592c228 283 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 01-11-2018 IPR024002 Formate/nitrite transporter, conserved site MLA2C4_08880 b05cbf1e3c7b968135bb75020f31bf55 211 Pfam PF00190 Cupin 39 163 9.5E-17 T 01-11-2018 IPR006045 Cupin 1 GO:0045735 MLA2C4_08880 b05cbf1e3c7b968135bb75020f31bf55 211 SMART SM00835 28 166 1.1E-33 T 01-11-2018 IPR006045 Cupin 1 GO:0045735 MLA2C4_08880 b05cbf1e3c7b968135bb75020f31bf55 211 SUPERFAMILY SSF51182 24 181 6.5E-29 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_08880 b05cbf1e3c7b968135bb75020f31bf55 211 Gene3D G3DSA:2.60.120.10 15 181 6.5E-36 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_18580 85b5e7abadc090db03c48f3b03c7a965 127 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 7 48 3.0E-17 T 01-11-2018 MLA2C4_05925 454e213002408883996ad9b5af543b89 219 Pfam PF00395 S-layer homology domain 98 142 8.5E-13 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05925 454e213002408883996ad9b5af543b89 219 Pfam PF00395 S-layer homology domain 158 201 4.1E-13 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05925 454e213002408883996ad9b5af543b89 219 Pfam PF00395 S-layer homology domain 38 80 7.2E-9 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04145 8e5a4849c3ea5d6dfed33d8e8b90a149 437 SUPERFAMILY SSF81301 17 157 1.93E-21 T 01-11-2018 MLA2C4_04145 8e5a4849c3ea5d6dfed33d8e8b90a149 437 Gene3D G3DSA:3.30.460.10 16 175 6.4E-9 T 01-11-2018 MLA2C4_20585 111f8172be5a867bf60ee9cc4e0901f6 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 5 109 3.7E-45 T 01-11-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MLA2C4_20585 111f8172be5a867bf60ee9cc4e0901f6 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 28 101 7.2E-14 T 01-11-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 556 28.129 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Gene3D G3DSA:1.10.730.10 432 556 6.2E-172 T 01-11-2018 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Pfam PF05746 DALR anticodon binding domain 438 556 4.3E-36 T 01-11-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 94 4.2E-25 T 01-11-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 4.9E-25 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 4.9E-25 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 4.9E-25 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 4.9E-25 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 SUPERFAMILY SSF55190 6 115 4.84E-27 T 01-11-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 01-11-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Gene3D G3DSA:3.40.50.620 124 431 6.2E-172 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 556 9.0E-169 T 01-11-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 SUPERFAMILY SSF52374 118 448 8.31E-95 T 01-11-2018 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Gene3D G3DSA:3.30.1360.70 3 113 1.9E-27 T 01-11-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 SMART SM00836 437 556 3.3E-55 T 01-11-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 SMART SM01016 5 95 6.6E-35 T 01-11-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 SUPERFAMILY SSF47323 431 556 3.73E-35 T 01-11-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MLA2C4_27770 85ade635b084a0db7c99010df876d979 556 Pfam PF00750 tRNA synthetases class I (R) 107 403 1.2E-24 T 01-11-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MLA2C4_00740 0a8b9c4db87204f6ab3c67991aa791df 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.4E-25 T 01-11-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_00740 0a8b9c4db87204f6ab3c67991aa791df 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 01-11-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00740 0a8b9c4db87204f6ab3c67991aa791df 61 SUPERFAMILY SSF57716 3 61 5.42E-22 T 01-11-2018 MLA2C4_00740 0a8b9c4db87204f6ab3c67991aa791df 61 Gene3D G3DSA:4.10.830.10 1 61 4.8E-31 T 01-11-2018 MLA2C4_00740 0a8b9c4db87204f6ab3c67991aa791df 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.091 T 01-11-2018 IPR023053 Ribosomal protein S14, type Z MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 SUPERFAMILY SSF69189 298 392 2.35E-17 T 01-11-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 Gene3D G3DSA:3.40.710.10 29 306 5.8E-91 T 01-11-2018 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 SMART SM00936 306 408 1.6E-18 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 SUPERFAMILY SSF56601 4 306 2.82E-77 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 285 4.7E-82 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.5E-14 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.5E-14 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 1.5E-14 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 306 408 2.4E-16 T 01-11-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_00070 81867aea92aef51d5fdac745c219fab1 438 Gene3D G3DSA:2.60.410.10 307 408 2.0E-17 T 01-11-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MLA2C4_24625 aad7957473d17f74d2fcf32a265264ea 359 Gene3D G3DSA:3.30.300.210 219 359 2.6E-19 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_24625 aad7957473d17f74d2fcf32a265264ea 359 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 358 1.2E-91 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_24625 aad7957473d17f74d2fcf32a265264ea 359 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 197 356 1.8E-27 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 Gene3D G3DSA:1.10.10.10 125 229 1.4E-34 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 SMART SM00862 151 227 8.5E-27 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 2.3E-25 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 SUPERFAMILY SSF52172 3 128 1.04E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 Gene3D G3DSA:3.40.50.2300 1 121 1.7E-33 T 01-11-2018 MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 SUPERFAMILY SSF46894 130 227 3.97E-30 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_09430 2fd2fd78cea4288b3cb0ef6e2bb5411b 229 SMART SM00448 2 112 8.5E-38 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_23360 e59c4f484f9642da8f49de0cc3918b36 167 SUPERFAMILY SSF56300 1 162 2.78E-44 T 01-11-2018 MLA2C4_23360 e59c4f484f9642da8f49de0cc3918b36 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 1.4E-31 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MLA2C4_23360 e59c4f484f9642da8f49de0cc3918b36 167 Gene3D G3DSA:3.60.21.10 1 165 6.5E-46 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_23360 e59c4f484f9642da8f49de0cc3918b36 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 148 4.2E-31 T 01-11-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 MLA2C4_15530 2790b414c464a402bbebb1c0c4687716 657 Gene3D G3DSA:3.40.720.10 244 552 6.1E-83 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_15530 2790b414c464a402bbebb1c0c4687716 657 PIRSF PIRSF005091 1 626 5.7E-197 T 01-11-2018 IPR012160 Lipoteichoic acid synthase-like MLA2C4_15530 2790b414c464a402bbebb1c0c4687716 657 Pfam PF00884 Sulfatase 253 541 2.1E-39 T 01-11-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MLA2C4_15530 2790b414c464a402bbebb1c0c4687716 657 SUPERFAMILY SSF53649 250 644 1.44E-82 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_19675 764b2634491dcacf6c2dd26e3e0cd449 639 Pfam PF00884 Sulfatase 248 538 4.3E-38 T 01-11-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MLA2C4_19675 764b2634491dcacf6c2dd26e3e0cd449 639 PIRSF PIRSF005091 1 623 4.1E-172 T 01-11-2018 IPR012160 Lipoteichoic acid synthase-like MLA2C4_19675 764b2634491dcacf6c2dd26e3e0cd449 639 SUPERFAMILY SSF53649 246 619 1.83E-72 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_19675 764b2634491dcacf6c2dd26e3e0cd449 639 Gene3D G3DSA:3.40.720.10 241 548 9.8E-74 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 SUPERFAMILY SSF81464 14 116 2.13E-21 T 01-11-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 Gene3D G3DSA:1.10.287.90 27 113 5.7E-26 T 01-11-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 150 227 1.8E-15 T 01-11-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 Gene3D G3DSA:2.60.40.2600 126 349 4.8E-69 T 01-11-2018 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 31 237 1.2E-55 T 01-11-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 Pfam PF00034 Cytochrome c 254 346 1.9E-13 T 01-11-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 SUPERFAMILY SSF49503 124 289 4.18E-43 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 SUPERFAMILY SSF46626 249 346 1.05E-18 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 107 2.1E-10 T 01-11-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 210 227 1.2E-14 T 01-11-2018 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 192 209 1.2E-14 T 01-11-2018 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 116 1.2E-14 T 01-11-2018 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 172 192 1.2E-14 T 01-11-2018 MLA2C4_20600 69ce71e75a1141ad2934186ad87578e9 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 84 96 1.2E-14 T 01-11-2018 MLA2C4_13985 da6473e13755791a1990c0ddd14b5be4 257 Pfam PF13105 Protein of unknown function (DUF3959) 9 253 1.6E-156 T 01-11-2018 IPR025080 Protein of unknown function DUF3959 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 SUPERFAMILY SSF58104 225 561 3.01E-76 T 01-11-2018 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 Pfam PF00672 HAMP domain 207 254 1.7E-8 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 SMART SM00304 203 257 4.3E-12 T 01-11-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 SMART SM00283 286 561 4.5E-81 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 Gene3D G3DSA:1.20.1480.50 163 259 1.1E-13 T 01-11-2018 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 514 3.7E-47 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_26240 1992f6d16464a4ee57675895f05d642d 563 Gene3D G3DSA:1.10.287.950 260 561 1.6E-69 T 01-11-2018 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 119 25.897 T 01-11-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 119 5.7E-50 T 01-11-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 Gene3D G3DSA:3.30.1390.10 49 119 2.6E-32 T 01-11-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 48 1.1E-20 T 01-11-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 SUPERFAMILY SSF54736 49 119 7.15E-26 T 01-11-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 53 119 8.9E-32 T 01-11-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 54 119 6.0E-17 T 01-11-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 SUPERFAMILY SSF48300 1 55 1.07E-16 T 01-11-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00620 489e26424ca923853bbcdfdc192f6f87 119 Gene3D G3DSA:1.20.5.710 1 48 1.4E-22 T 01-11-2018 MLA2C4_25110 d4708f0cad0376860beffe0b08431a3c 152 SUPERFAMILY SSF47413 8 64 5.07E-9 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_25110 d4708f0cad0376860beffe0b08431a3c 152 Gene3D G3DSA:1.10.260.40 10 55 6.3E-8 T 01-11-2018 MLA2C4_25110 d4708f0cad0376860beffe0b08431a3c 152 Pfam PF01381 Helix-turn-helix 14 49 1.6E-5 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_01570 83706222435c096912856688ee211565 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 01-11-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.064 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 Gene3D G3DSA:2.30.33.40 1 93 2.6E-38 T 01-11-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.8E-32 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.8E-32 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.8E-32 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.8E-32 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 4.3E-36 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_01570 83706222435c096912856688ee211565 94 SUPERFAMILY SSF50129 1 93 2.45E-35 T 01-11-2018 IPR011032 GroES-like superfamily MLA2C4_01570 83706222435c096912856688ee211565 94 SMART SM00883 1 93 6.2E-58 T 01-11-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MLA2C4_08165 2b5bfdfe76c385ffd4ad23bca075e61e 114 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 11 112 2.0E-34 T 01-11-2018 IPR014913 Protein of unknown function DUF1798 MLA2C4_08165 2b5bfdfe76c385ffd4ad23bca075e61e 114 SUPERFAMILY SSF140415 5 114 1.26E-39 T 01-11-2018 IPR023351 YppE-like superfamily MLA2C4_08165 2b5bfdfe76c385ffd4ad23bca075e61e 114 Gene3D G3DSA:1.20.120.440 2 114 4.6E-33 T 01-11-2018 IPR023351 YppE-like superfamily MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 Gene3D G3DSA:1.10.10.10 1 95 2.4E-6 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 SUPERFAMILY SSF100950 81 231 2.44E-19 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 3.6E-15 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.0E-8 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.0E-8 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 SMART SM00420 6 58 1.7E-12 T 01-11-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 SUPERFAMILY SSF46785 4 60 7.3E-13 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 Pfam PF00455 DeoR C terminal sensor domain 81 231 2.6E-29 T 01-11-2018 IPR014036 DeoR C-terminal sensor domain MLA2C4_14665 85cbbd9a05bff03066c4fa48a36da16c 256 SMART SM01134 77 232 2.8E-35 T 01-11-2018 MLA2C4_08510 bb26ad47209bd768796fdfade8b0c9ec 200 SUPERFAMILY SSF109604 3 177 1.94E-36 T 01-11-2018 MLA2C4_08510 bb26ad47209bd768796fdfade8b0c9ec 200 Gene3D G3DSA:1.10.3210.10 2 191 1.8E-47 T 01-11-2018 MLA2C4_08510 bb26ad47209bd768796fdfade8b0c9ec 200 Pfam PF13023 HD domain 12 169 6.1E-49 T 01-11-2018 IPR006674 HD domain MLA2C4_25770 1c29446ddd06fff9b6113630775e9e9c 333 Gene3D G3DSA:3.90.1200.10 90 313 2.2E-23 T 01-11-2018 MLA2C4_25770 1c29446ddd06fff9b6113630775e9e9c 333 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 4 313 4.9E-109 T 01-11-2018 IPR014254 Spore coat protein YutH MLA2C4_25770 1c29446ddd06fff9b6113630775e9e9c 333 SUPERFAMILY SSF56112 5 314 2.04E-16 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_20235 c3cca543446ff4e5da6aa879e24955d4 87 Hamap MF_01503 UPF0296 protein . 3 86 28.228 T 01-11-2018 IPR007169 Extracellular matrix regulatory protein A MLA2C4_20235 c3cca543446ff4e5da6aa879e24955d4 87 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 6 78 2.0E-36 T 01-11-2018 IPR007169 Extracellular matrix regulatory protein A MLA2C4_20235 c3cca543446ff4e5da6aa879e24955d4 87 Pfam PF04025 Domain of unknown function (DUF370) 5 77 5.3E-36 T 01-11-2018 IPR007169 Extracellular matrix regulatory protein A MLA2C4_18205 b90a094807caa289669856a26d8b4397 488 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 474 46.601 T 01-11-2018 IPR003846 Uncharacterised protein family UPF0061 MLA2C4_18205 b90a094807caa289669856a26d8b4397 488 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 12 458 7.8E-122 T 01-11-2018 IPR003846 Uncharacterised protein family UPF0061 MLA2C4_17890 7d04611f498c48d33d379fba9be1aec6 249 PIRSF PIRSF006648 1 249 4.2E-66 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MLA2C4_17890 7d04611f498c48d33d379fba9be1aec6 249 Pfam PF01061 ABC-2 type transporter 5 214 5.0E-24 T 01-11-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MLA2C4_23470 99deb6bc458f2b38f89ae36e4012ffae 259 Gene3D G3DSA:3.30.1380.10 50 259 9.2E-79 T 01-11-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MLA2C4_23470 99deb6bc458f2b38f89ae36e4012ffae 259 SUPERFAMILY SSF55166 93 246 4.97E-40 T 01-11-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MLA2C4_23470 99deb6bc458f2b38f89ae36e4012ffae 259 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 110 237 1.4E-47 T 01-11-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MLA2C4_08740 5655037564ff6a4fc139eaebeed07528 432 Gene3D G3DSA:3.20.20.30 2 429 2.1E-100 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_08740 5655037564ff6a4fc139eaebeed07528 432 SUPERFAMILY SSF51679 24 424 7.2E-91 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_08740 5655037564ff6a4fc139eaebeed07528 432 PIRSF PIRSF000337 8 430 2.3E-112 T 01-11-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MLA2C4_08740 5655037564ff6a4fc139eaebeed07528 432 Pfam PF00296 Luciferase-like monooxygenase 26 375 5.4E-52 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MLA2C4_08740 5655037564ff6a4fc139eaebeed07528 432 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 16 420 3.2E-101 T 01-11-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 MLA2C4_18085 0e558efee4ed5fe7c26a39ecdac4d7ab 162 Gene3D G3DSA:1.20.120.450 2 162 1.7E-31 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_18085 0e558efee4ed5fe7c26a39ecdac4d7ab 162 SUPERFAMILY SSF109854 1 160 1.12E-30 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_18085 0e558efee4ed5fe7c26a39ecdac4d7ab 162 Pfam PF05163 DinB family 6 161 2.2E-22 T 01-11-2018 IPR007837 DNA damage-inducible protein DinB MLA2C4_10665 65a2563cb5863413805e18b379d95811 82 Pfam PF13780 Domain of unknown function (DUF4176) 3 73 6.9E-24 T 01-11-2018 IPR025233 Protein of unknown function DUF4176 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 01-11-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 396 54.757 T 01-11-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 SUPERFAMILY SSF52402 1 170 1.04E-47 T 01-11-2018 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 394 6.5E-174 T 01-11-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 SUPERFAMILY SSF69864 170 397 1.01E-95 T 01-11-2018 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 Pfam PF00764 Arginosuccinate synthase 7 391 7.5E-181 T 01-11-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 01-11-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 Gene3D G3DSA:3.40.50.620 1 173 2.1E-66 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_24060 74ac4dcb551aa0f2c80d1d6c0401a8c0 401 Gene3D G3DSA:3.90.1260.10 174 401 1.6E-95 T 01-11-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MLA2C4_22775 226e6b62d309d60e13732e1c1c1998ff 131 Gene3D G3DSA:1.25.40.20 15 128 6.5E-10 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_22775 226e6b62d309d60e13732e1c1c1998ff 131 SUPERFAMILY SSF48403 17 114 3.42E-9 T 01-11-2018 IPR036770 Ankyrin repeat-containing domain superfamily MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 SUPERFAMILY SSF55729 4 151 1.17E-20 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 Gene3D G3DSA:3.40.630.30 1 157 2.1E-21 T 01-11-2018 MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 Pfam PF13599 Pentapeptide repeats (9 copies) 171 247 5.1E-15 T 01-11-2018 IPR001646 Pentapeptide repeat MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 Pfam PF00805 Pentapeptide repeats (8 copies) 261 289 0.0095 T 01-11-2018 IPR001646 Pentapeptide repeat MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 Pfam PF13508 Acetyltransferase (GNAT) domain 69 142 1.1E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 Gene3D G3DSA:2.160.20.80 158 300 6.1E-19 T 01-11-2018 MLA2C4_12405 8fb52afe1401c9740577434b7699e9f6 308 SUPERFAMILY SSF141571 168 298 1.27E-21 T 01-11-2018 MLA2C4_21910 6e22f5223b0e8ee55ab08202934ef67d 210 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 199 5.5E-34 T 01-11-2018 IPR014245 Sporulation stage III, protein AF MLA2C4_21910 6e22f5223b0e8ee55ab08202934ef67d 210 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 2 111 1.7E-36 T 01-11-2018 IPR014245 Sporulation stage III, protein AF MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 Gene3D G3DSA:1.10.8.450 247 280 1.7E-95 T 01-11-2018 MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 SUPERFAMILY SSF53850 31 258 8.39E-52 T 01-11-2018 MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 Pfam PF09084 NMT1/THI5 like 44 246 5.8E-29 T 01-11-2018 IPR015168 SsuA/THI5-like MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 321 8.1E-93 T 01-11-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 Gene3D G3DSA:3.40.190.10 35 311 1.7E-95 T 01-11-2018 MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 SMART SM00062 34 278 2.8E-24 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_15435 5dc73e80bebb9004ca3a4166ff946362 328 Gene3D G3DSA:3.40.190.10 115 214 1.7E-95 T 01-11-2018 MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 355 408 4.1E-6 T 01-11-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 SMART SM00849 14 223 1.6E-9 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 SUPERFAMILY SSF56281 2 403 9.48E-68 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 SMART SM01027 236 347 7.2E-5 T 01-11-2018 IPR022712 Beta-Casp domain MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 Pfam PF12706 Beta-lactamase superfamily domain 25 205 2.5E-11 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 Gene3D G3DSA:3.40.50.10890 204 363 1.0E-83 T 01-11-2018 MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 Gene3D G3DSA:3.60.15.10 8 391 1.0E-83 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_08855 03228736d0a5dca6b48f38d847b9b80a 420 Pfam PF10996 Beta-Casp domain 246 346 2.7E-6 T 01-11-2018 IPR022712 Beta-Casp domain MLA2C4_17300 97b047df57cea0a39a9ebcdc5576eedb 191 SUPERFAMILY SSF52218 2 191 4.5E-54 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_17300 97b047df57cea0a39a9ebcdc5576eedb 191 Pfam PF02525 Flavodoxin-like fold 2 186 6.5E-43 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_17300 97b047df57cea0a39a9ebcdc5576eedb 191 Gene3D G3DSA:3.40.50.360 1 191 7.7E-55 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_12600 dfc8717b413fe8a6ae35b724ba47a18b 141 Pfam PF05105 Bacteriophage holin family 19 127 7.1E-38 T 01-11-2018 IPR006480 Bacteriophage holin family MLA2C4_12600 dfc8717b413fe8a6ae35b724ba47a18b 141 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 13 137 3.6E-30 T 01-11-2018 IPR006480 Bacteriophage holin family MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 Gene3D G3DSA:3.40.50.720 12 275 3.5E-69 T 01-11-2018 MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.8E-21 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 4.8E-21 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 4.8E-21 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 4.8E-21 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 4.8E-21 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 SUPERFAMILY SSF51735 13 285 4.06E-60 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 Pfam PF00106 short chain dehydrogenase 14 201 8.5E-48 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 5.7E-10 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 5.7E-10 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 5.7E-10 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_14710 8fec1e64b70235fe6663d7084df88291 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 Pfam PF12840 Helix-turn-helix domain 17 72 2.6E-10 T 01-11-2018 MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 7.5E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 7.5E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 7.5E-9 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 Gene3D G3DSA:1.10.10.10 1 94 2.4E-25 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 SUPERFAMILY SSF46785 7 93 7.34E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03225 a6014b8dd6f84bf892aa6165feedc8ce 95 SMART SM00418 16 95 2.9E-23 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_05005 187d028ab925df043894ddb96710c6da 81 SUPERFAMILY SSF52540 12 78 4.73E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05005 187d028ab925df043894ddb96710c6da 81 Pfam PF03796 DnaB-like helicase C terminal domain 6 78 6.2E-22 T 01-11-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MLA2C4_05005 187d028ab925df043894ddb96710c6da 81 Gene3D G3DSA:3.40.50.300 2 81 1.7E-22 T 01-11-2018 MLA2C4_17975 4ee3161ea79b3a5d3c8c2e30b3a74c2d 154 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 135 3.7E-24 T 01-11-2018 IPR006750 Putative inner membrane exporter, YdcZ MLA2C4_05495 84d30902a8de73447f811682ce6ba701 149 SUPERFAMILY SSF47413 1 67 8.45E-21 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_05495 84d30902a8de73447f811682ce6ba701 149 SMART SM00530 6 61 1.3E-18 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_05495 84d30902a8de73447f811682ce6ba701 149 Gene3D G3DSA:1.10.260.40 1 72 2.1E-24 T 01-11-2018 MLA2C4_05495 84d30902a8de73447f811682ce6ba701 149 Pfam PF01381 Helix-turn-helix 7 61 6.4E-18 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_23115 38b219b9a37e596a3741d4a5954d19c3 215 Gene3D G3DSA:2.40.33.20 2 215 8.1E-68 T 01-11-2018 MLA2C4_23115 38b219b9a37e596a3741d4a5954d19c3 215 Pfam PF03475 3-alpha domain 171 213 2.2E-12 T 01-11-2018 IPR005163 3-alpha domain MLA2C4_23115 38b219b9a37e596a3741d4a5954d19c3 215 Pfam PF03473 MOSC domain 50 161 9.6E-21 T 01-11-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MLA2C4_23115 38b219b9a37e596a3741d4a5954d19c3 215 SUPERFAMILY SSF50800 5 213 9.42E-67 T 01-11-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MLA2C4_20610 9f1ccb4311e34449710ed802f7daa5b6 311 Pfam PF02628 Cytochrome oxidase assembly protein 7 286 7.2E-40 T 01-11-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MLA2C4_20610 9f1ccb4311e34449710ed802f7daa5b6 311 Hamap MF_01664 Heme A synthase [ctaA]. 1 301 30.896 T 01-11-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 167 1.8E-29 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 Pfam PF08281 Sigma-70, region 4 112 163 1.4E-14 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 SUPERFAMILY SSF88659 100 168 1.08E-16 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 Gene3D G3DSA:1.10.1740.10 1 77 2.5E-18 T 01-11-2018 MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 Pfam PF04542 Sigma-70 region 2 8 75 2.5E-12 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 Gene3D G3DSA:1.10.10.10 106 170 2.7E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_27765 b4c4ce32038b8c1fc7e0b358e87e45f6 175 SUPERFAMILY SSF88946 4 86 7.85E-19 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 Pfam PF07690 Major Facilitator Superfamily 6 227 1.4E-31 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 Pfam PF03209 PUCC protein 270 351 2.8E-6 T 01-11-2018 IPR004896 PucC-related MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 Gene3D G3DSA:1.20.1250.20 2 374 1.1E-58 T 01-11-2018 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 PRINTS PR01035 Tetracycline resistance protein signature 37 56 4.3E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 PRINTS PR01035 Tetracycline resistance protein signature 267 288 4.3E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 PRINTS PR01035 Tetracycline resistance protein signature 126 148 4.3E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 PRINTS PR01035 Tetracycline resistance protein signature 239 259 4.3E-6 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_03550 43cd9d752e9da1b6d5be68daa96249cf 384 SUPERFAMILY SSF103473 4 376 1.31E-62 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_18885 a1cdf30a461f1b5cd0ed0676808ea144 270 Gene3D G3DSA:3.40.630.30 62 244 8.6E-13 T 01-11-2018 MLA2C4_18885 a1cdf30a461f1b5cd0ed0676808ea144 270 SUPERFAMILY SSF55729 96 242 4.18E-12 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 429 1.3E-16 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 430 7.2E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 7.2E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 7.2E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 7.2E-11 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 SMART SM00387 321 433 1.3E-18 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 SUPERFAMILY SSF55874 283 429 3.01E-27 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_16445 3ea2571b407253ec1f2e836730b2e59d 438 Gene3D G3DSA:3.30.565.10 282 432 9.0E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_05835 f494a2afa688c6b7d9b26cffff9fac11 368 Gene3D G3DSA:3.60.21.10 146 338 1.2E-22 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_05835 f494a2afa688c6b7d9b26cffff9fac11 368 Pfam PF00149 Calcineurin-like phosphoesterase 148 311 2.4E-12 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_05835 f494a2afa688c6b7d9b26cffff9fac11 368 SUPERFAMILY SSF56300 145 366 6.68E-34 T 01-11-2018 MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.4E-36 T 01-11-2018 IPR027486 Ribosomal protein S10 domain MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 SUPERFAMILY SSF54999 5 102 1.2E-38 T 01-11-2018 IPR036838 Ribosomal protein S10 domain superfamily MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 SMART SM01403 7 101 8.1E-60 T 01-11-2018 IPR027486 Ribosomal protein S10 domain MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.5E-46 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 01-11-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 Gene3D G3DSA:3.30.70.600 1 102 5.3E-38 T 01-11-2018 IPR036838 Ribosomal protein S10 domain superfamily MLA2C4_00670 35868332db1e892ba7188e536bd58957 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.164 T 01-11-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_24115 d9f524967a5a39093861fcd566333125 212 Pfam PF11167 Protein of unknown function (DUF2953) 121 173 1.5E-19 T 01-11-2018 IPR021338 Protein of unknown function DUF2953 MLA2C4_04925 ae7970dfc201b8e0fadb188824d4d42f 323 Gene3D G3DSA:3.40.190.10 125 251 1.6E-60 T 01-11-2018 MLA2C4_04925 ae7970dfc201b8e0fadb188824d4d42f 323 Gene3D G3DSA:3.40.190.150 33 316 1.6E-60 T 01-11-2018 MLA2C4_04925 ae7970dfc201b8e0fadb188824d4d42f 323 SUPERFAMILY SSF53850 113 289 1.9E-9 T 01-11-2018 MLA2C4_04925 ae7970dfc201b8e0fadb188824d4d42f 323 PIRSF PIRSF017082 1 323 3.0E-88 T 01-11-2018 IPR005064 Bordetella uptake gene GO:0030288 MLA2C4_04925 ae7970dfc201b8e0fadb188824d4d42f 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 318 3.0E-24 T 01-11-2018 IPR005064 Bordetella uptake gene GO:0030288 MLA2C4_08715 cf9f9630684e92846f9fd47fc4a099ae 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 72 91 5.5E-14 T 01-11-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MLA2C4_08715 cf9f9630684e92846f9fd47fc4a099ae 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 194 213 5.5E-14 T 01-11-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MLA2C4_08715 cf9f9630684e92846f9fd47fc4a099ae 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 172 194 5.5E-14 T 01-11-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MLA2C4_08715 cf9f9630684e92846f9fd47fc4a099ae 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 15 36 5.5E-14 T 01-11-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MLA2C4_08715 cf9f9630684e92846f9fd47fc4a099ae 253 Pfam PF01311 Bacterial export proteins, family 1 8 237 4.4E-48 T 01-11-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MLA2C4_17960 63708237a1872419b439405750dadd91 96 Gene3D G3DSA:3.10.180.10 1 95 6.4E-12 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_17960 63708237a1872419b439405750dadd91 96 SUPERFAMILY SSF54593 4 89 4.95E-12 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18245 26398938b8821f0b2df0301616739f2c 132 Pfam PF11070 Protein of unknown function (DUF2871) 1 128 9.3E-38 T 01-11-2018 IPR021299 Protein of unknown function DUF2871 MLA2C4_12605 9b8f3ae44a720126e267580cf4f86c1d 265 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 222 264 1.7E-21 T 01-11-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase MetaCyc: PWY-7883 MLA2C4_12605 9b8f3ae44a720126e267580cf4f86c1d 265 Gene3D G3DSA:3.20.20.80 2 188 1.0E-74 T 01-11-2018 MLA2C4_12605 9b8f3ae44a720126e267580cf4f86c1d 265 Gene3D G3DSA:3.30.70.2030 189 265 1.8E-41 T 01-11-2018 MLA2C4_12605 9b8f3ae44a720126e267580cf4f86c1d 265 SUPERFAMILY SSF51445 4 187 4.53E-44 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_12605 9b8f3ae44a720126e267580cf4f86c1d 265 Pfam PF01183 Glycosyl hydrolases family 25 5 168 5.2E-26 T 01-11-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 MLA2C4_14300 e9a18c6f5567f5e5c96410ef47d73f2e 129 SUPERFAMILY SSF55608 76 117 2.43E-6 T 01-11-2018 IPR027434 Homing endonuclease MLA2C4_14300 e9a18c6f5567f5e5c96410ef47d73f2e 129 Gene3D G3DSA:3.10.28.10 74 129 2.4E-5 T 01-11-2018 IPR027434 Homing endonuclease MLA2C4_26015 750532f4afc043fadbb5f8412f636e53 61 Gene3D G3DSA:1.20.1260.10 8 60 3.8E-5 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_22195 39bfe39241a9e0954b5989a46ad6110f 231 Pfam PF12840 Helix-turn-helix domain 7 63 1.0E-6 T 01-11-2018 MLA2C4_22195 39bfe39241a9e0954b5989a46ad6110f 231 SUPERFAMILY SSF46785 1 204 1.33E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22195 39bfe39241a9e0954b5989a46ad6110f 231 Gene3D G3DSA:1.10.10.10 1 92 6.8E-13 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20270 fc1e5596a12b84c8c4d44628a2428d97 174 SUPERFAMILY SSF109854 7 167 3.3E-39 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_20270 fc1e5596a12b84c8c4d44628a2428d97 174 Pfam PF04978 Protein of unknown function (DUF664) 18 164 4.3E-10 T 01-11-2018 IPR007061 Protein of unknown function DUF664 MLA2C4_20270 fc1e5596a12b84c8c4d44628a2428d97 174 Gene3D G3DSA:1.20.120.450 3 170 9.5E-45 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_07300 faecc96607cbb075981580904be40b61 300 Gene3D G3DSA:3.30.200.20 1 96 1.1E-21 T 01-11-2018 MLA2C4_07300 faecc96607cbb075981580904be40b61 300 Gene3D G3DSA:3.90.1200.10 97 298 6.4E-52 T 01-11-2018 MLA2C4_07300 faecc96607cbb075981580904be40b61 300 SUPERFAMILY SSF56112 7 258 3.06E-31 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_07300 faecc96607cbb075981580904be40b61 300 Pfam PF01636 Phosphotransferase enzyme family 22 247 1.3E-24 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_03115 ed3938563015cfd78eabce4e808b8894 168 Pfam PF13420 Acetyltransferase (GNAT) domain 3 159 1.1E-18 T 01-11-2018 MLA2C4_03115 ed3938563015cfd78eabce4e808b8894 168 Gene3D G3DSA:3.40.630.30 1 167 1.1E-41 T 01-11-2018 MLA2C4_03115 ed3938563015cfd78eabce4e808b8894 168 SUPERFAMILY SSF55729 1 167 1.13E-29 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10065 24776eff7ca0a4a63d466bab1a05e746 226 Pfam PF02308 MgtC family 9 138 3.1E-34 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_10065 24776eff7ca0a4a63d466bab1a05e746 226 PRINTS PR01837 MgtC/SapB protein signature 93 117 3.7E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_10065 24776eff7ca0a4a63d466bab1a05e746 226 PRINTS PR01837 MgtC/SapB protein signature 12 31 3.7E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_10065 24776eff7ca0a4a63d466bab1a05e746 226 PRINTS PR01837 MgtC/SapB protein signature 65 87 3.7E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_10065 24776eff7ca0a4a63d466bab1a05e746 226 PRINTS PR01837 MgtC/SapB protein signature 31 49 3.7E-40 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_05275 2a9014e2fac280c825b27eeb42c6cddb 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 32 3.5E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_05275 2a9014e2fac280c825b27eeb42c6cddb 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 34 1.2E-10 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_17400 a020086ea581a876f8eddc7dd55661ec 158 PIRSF PIRSF006181 1 158 1.8E-61 T 01-11-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MLA2C4_17400 a020086ea581a876f8eddc7dd55661ec 158 SUPERFAMILY SSF55826 6 157 4.58E-38 T 01-11-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_17400 a020086ea581a876f8eddc7dd55661ec 158 Pfam PF04073 Aminoacyl-tRNA editing domain 36 147 7.2E-19 T 01-11-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_17400 a020086ea581a876f8eddc7dd55661ec 158 Gene3D G3DSA:3.90.960.10 1 158 2.5E-49 T 01-11-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_17400 a020086ea581a876f8eddc7dd55661ec 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 157 1.1E-62 T 01-11-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MLA2C4_16645 f876267f160a1594618edd68d1c60ec6 173 SUPERFAMILY SSF53056 4 160 7.59E-18 T 01-11-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MLA2C4_16645 f876267f160a1594618edd68d1c60ec6 173 Gene3D G3DSA:3.40.1050.10 1 160 5.5E-13 T 01-11-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MLA2C4_18605 1bcbec59246a127599a95b98f78e8369 567 Gene3D G3DSA:3.40.190.10 68 552 1.5E-182 T 01-11-2018 MLA2C4_18605 1bcbec59246a127599a95b98f78e8369 567 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 481 7.1E-80 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_18605 1bcbec59246a127599a95b98f78e8369 567 SUPERFAMILY SSF53850 52 563 1.49E-123 T 01-11-2018 MLA2C4_18605 1bcbec59246a127599a95b98f78e8369 567 Gene3D G3DSA:3.90.76.10 87 209 1.5E-182 T 01-11-2018 MLA2C4_18605 1bcbec59246a127599a95b98f78e8369 567 Gene3D G3DSA:3.10.105.10 310 537 1.5E-182 T 01-11-2018 MLA2C4_18605 1bcbec59246a127599a95b98f78e8369 567 PIRSF PIRSF002741 3 567 9.2E-106 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_23660 1d537ec400db71e725e0faeb8ab2ef5b 179 Pfam PF02674 Colicin V production protein 2 159 8.9E-34 T 01-11-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MLA2C4_08685 2527e72287c1ece1d4a88aba8b3e392c 74 SUPERFAMILY SSF101801 3 72 1.31E-13 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_08685 2527e72287c1ece1d4a88aba8b3e392c 74 Gene3D G3DSA:2.30.330.10 1 74 1.4E-12 T 01-11-2018 IPR036429 SpoA-like superfamily MLA2C4_08685 2527e72287c1ece1d4a88aba8b3e392c 74 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 5 72 3.3E-10 T 01-11-2018 IPR001543 Surface presentation of antigen (SpoA) MLA2C4_08685 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 49 64 1.7E-5 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08685 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 3 19 1.7E-5 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_08685 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 20 36 1.7E-5 T 01-11-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MLA2C4_21225 4d1142eef5be796caacb1b31ed73dfe3 247 Gene3D G3DSA:1.10.10.580 179 242 4.4E-5 T 01-11-2018 IPR023093 ScpA-like, C-terminal MLA2C4_21225 4d1142eef5be796caacb1b31ed73dfe3 247 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 244 26.903 T 01-11-2018 IPR003768 Segregation and condensation protein A MLA2C4_21225 4d1142eef5be796caacb1b31ed73dfe3 247 Pfam PF02616 Segregation and condensation protein ScpA 20 241 1.3E-55 T 01-11-2018 IPR003768 Segregation and condensation protein A MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 Pfam PF13567 Domain of unknown function (DUF4131) 24 164 1.4E-19 T 01-11-2018 IPR025405 Domain of unknown function DUF4131 MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 SMART SM00849 509 719 3.7E-13 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 Gene3D G3DSA:3.60.15.10 498 765 9.1E-75 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 78 748 1.8E-129 T 01-11-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 228 398 3.6E-36 T 01-11-2018 IPR004477 ComEC/Rec2-related protein MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 SUPERFAMILY SSF56281 502 758 1.35E-54 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 Pfam PF03772 Competence protein 207 469 8.1E-66 T 01-11-2018 IPR004477 ComEC/Rec2-related protein MLA2C4_22585 df5449a93f60b38e005c7eb601389389 773 Pfam PF00753 Metallo-beta-lactamase superfamily 506 718 1.7E-17 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_22940 27c348532a44db408f21cd489c3ffbc7 138 Gene3D G3DSA:1.10.10.10 1 138 8.3E-52 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22940 27c348532a44db408f21cd489c3ffbc7 138 SUPERFAMILY SSF46785 2 125 9.43E-32 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_22940 27c348532a44db408f21cd489c3ffbc7 138 Pfam PF02082 Transcriptional regulator 1 82 2.2E-26 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_22940 27c348532a44db408f21cd489c3ffbc7 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 125 1.1E-34 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_22940 27c348532a44db408f21cd489c3ffbc7 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 01-11-2018 IPR030489 Transcription regulator Rrf2-type, conserved site MLA2C4_06245 01be004bfd9decacce3f910ccd2cb6d3 548 SUPERFAMILY SSF53850 40 542 2.9E-119 T 01-11-2018 MLA2C4_06245 01be004bfd9decacce3f910ccd2cb6d3 548 Gene3D G3DSA:3.10.105.10 298 519 5.0E-175 T 01-11-2018 MLA2C4_06245 01be004bfd9decacce3f910ccd2cb6d3 548 PIRSF PIRSF002741 1 548 4.3E-100 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_06245 01be004bfd9decacce3f910ccd2cb6d3 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 468 2.0E-73 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_06245 01be004bfd9decacce3f910ccd2cb6d3 548 Gene3D G3DSA:3.90.76.10 76 198 5.0E-175 T 01-11-2018 MLA2C4_06245 01be004bfd9decacce3f910ccd2cb6d3 548 Gene3D G3DSA:3.40.190.10 57 536 5.0E-175 T 01-11-2018 MLA2C4_07350 32a3464381a7b3f2c9d97bb78d1457f1 447 Pfam PF02386 Cation transport protein 45 427 8.9E-49 T 01-11-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MLA2C4_07350 32a3464381a7b3f2c9d97bb78d1457f1 447 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 36 418 1.5E-111 T 01-11-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 MLA2C4_18225 1e6b653e4d5863b1f3a8dbac24ba5706 175 Gene3D G3DSA:3.30.460.10 2 175 1.9E-49 T 01-11-2018 MLA2C4_18225 1e6b653e4d5863b1f3a8dbac24ba5706 175 SUPERFAMILY SSF81301 6 174 1.28E-43 T 01-11-2018 MLA2C4_18225 1e6b653e4d5863b1f3a8dbac24ba5706 175 Pfam PF04229 GrpB protein 5 171 6.1E-45 T 01-11-2018 IPR007344 GrpB/Dephospho-CoA kinase MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 PRINTS PR00095 Anthranilate synthase component I signature 406 420 2.9E-19 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 PRINTS PR00095 Anthranilate synthase component I signature 311 324 2.9E-19 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 PRINTS PR00095 Anthranilate synthase component I signature 391 405 2.9E-19 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 PRINTS PR00095 Anthranilate synthase component I signature 297 310 2.9E-19 T 01-11-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 SUPERFAMILY SSF56322 9 456 1.11E-151 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 Pfam PF04715 Anthranilate synthase component I, N terminal region 25 149 6.6E-32 T 01-11-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 Gene3D G3DSA:3.60.120.10 10 464 4.9E-168 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 Pfam PF00425 chorismate binding enzyme 196 449 1.5E-100 T 01-11-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MLA2C4_00390 9acf5d9ae5c42aee39a9963523cc9c62 465 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 20 457 3.4E-156 T 01-11-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_15940 4ed6665e28c3105db54a876f71b6d869 212 Pfam PF00881 Nitroreductase family 15 192 5.5E-33 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_15940 4ed6665e28c3105db54a876f71b6d869 212 SUPERFAMILY SSF55469 9 210 2.22E-60 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_15940 4ed6665e28c3105db54a876f71b6d869 212 Gene3D G3DSA:3.40.109.10 2 212 1.5E-63 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_17250 ba9d56078d733add714ce6e0735dceb3 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_17250 ba9d56078d733add714ce6e0735dceb3 399 Pfam PF07690 Major Facilitator Superfamily 15 338 4.3E-55 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_17250 ba9d56078d733add714ce6e0735dceb3 399 Gene3D G3DSA:1.20.1250.20 6 380 4.6E-60 T 01-11-2018 MLA2C4_17250 ba9d56078d733add714ce6e0735dceb3 399 SUPERFAMILY SSF103473 1 392 7.46E-69 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 SUPERFAMILY SSF48008 95 231 2.62E-29 T 01-11-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 Gene3D G3DSA:1.20.120.530 80 235 5.3E-32 T 01-11-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 SUPERFAMILY SSF46785 6 78 3.69E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 SMART SM00895 99 226 2.0E-22 T 01-11-2018 IPR011711 GntR, C-terminal MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 Gene3D G3DSA:1.10.10.10 1 74 6.5E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-18 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 Pfam PF07729 FCD domain 100 225 2.1E-23 T 01-11-2018 IPR011711 GntR, C-terminal MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 SMART SM00345 15 74 2.5E-18 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_06920 769c7905ecf95663089582174e25bd4d 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_20480 7e96c760d8324b4c422f757394350c1a 538 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 538 31.916 T 01-11-2018 IPR011199 Bacillithiol biosynthesis BshC MLA2C4_20480 7e96c760d8324b4c422f757394350c1a 538 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 10 536 1.3E-202 T 01-11-2018 IPR011199 Bacillithiol biosynthesis BshC MLA2C4_20480 7e96c760d8324b4c422f757394350c1a 538 PIRSF PIRSF012535 1 538 1.8E-238 T 01-11-2018 IPR011199 Bacillithiol biosynthesis BshC MLA2C4_20480 7e96c760d8324b4c422f757394350c1a 538 Pfam PF10079 Bacillithiol biosynthesis BshC 1 535 1.8E-178 T 01-11-2018 IPR011199 Bacillithiol biosynthesis BshC MLA2C4_05695 37db49a1a6dd2035d1a2b09463991ec9 167 Pfam PF03992 Antibiotic biosynthesis monooxygenase 56 129 5.4E-14 T 01-11-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MLA2C4_05695 37db49a1a6dd2035d1a2b09463991ec9 167 Gene3D G3DSA:3.30.70.3430 1 167 2.4E-49 T 01-11-2018 MLA2C4_05695 37db49a1a6dd2035d1a2b09463991ec9 167 SUPERFAMILY SSF54909 56 136 1.57E-23 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_03470 65b8f6043b8c983318e1666ab463d7ee 301 Gene3D G3DSA:1.10.3720.10 86 296 5.0E-18 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03470 65b8f6043b8c983318e1666ab463d7ee 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 9.6E-26 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03470 65b8f6043b8c983318e1666ab463d7ee 301 SUPERFAMILY SSF161098 90 285 2.62E-21 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03470 65b8f6043b8c983318e1666ab463d7ee 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 55 4.7E-7 T 01-11-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 Pfam PF13580 SIS domain 37 163 5.4E-8 T 01-11-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 5 294 3.7E-114 T 01-11-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 SUPERFAMILY SSF53697 5 247 2.0E-66 T 01-11-2018 MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 294 41.801 T 01-11-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 184 201 - T 01-11-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 Gene3D G3DSA:3.40.50.10490 1 217 7.1E-73 T 01-11-2018 MLA2C4_04505 53e1f7355c3424628943353971e4b8b2 294 Gene3D G3DSA:1.10.8.1080 218 294 1.4E-27 T 01-11-2018 MLA2C4_02570 40ca694728ff60956cffc016af213697 473 Gene3D G3DSA:1.20.1740.10 7 472 4.0E-69 T 01-11-2018 MLA2C4_02570 40ca694728ff60956cffc016af213697 473 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_02570 40ca694728ff60956cffc016af213697 473 Pfam PF00324 Amino acid permease 16 450 6.2E-127 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_02570 40ca694728ff60956cffc016af213697 473 PIRSF PIRSF006060 1 472 4.6E-86 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_20820 45ac102dd823905f47db0421657a15c1 147 SUPERFAMILY SSF54631 12 140 2.36E-28 T 01-11-2018 MLA2C4_20820 45ac102dd823905f47db0421657a15c1 147 Pfam PF00571 CBS domain 86 139 4.9E-6 T 01-11-2018 IPR000644 CBS domain MLA2C4_20820 45ac102dd823905f47db0421657a15c1 147 Gene3D G3DSA:3.10.580.10 1 147 7.7E-64 T 01-11-2018 MLA2C4_00510 042692b4bbaea54706a3c07b712ee48e 153 Gene3D G3DSA:1.10.10.1240 2 72 3.0E-35 T 01-11-2018 MLA2C4_00510 042692b4bbaea54706a3c07b712ee48e 153 Gene3D G3DSA:1.10.1200.150 73 153 6.5E-31 T 01-11-2018 MLA2C4_00510 042692b4bbaea54706a3c07b712ee48e 153 PIRSF PIRSF010607 1 153 3.1E-66 T 01-11-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 MLA2C4_00510 042692b4bbaea54706a3c07b712ee48e 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 7.6E-58 T 01-11-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 Gene3D G3DSA:1.10.150.470 1 84 6.9E-26 T 01-11-2018 MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 Pfam PF02384 N-6 DNA Methylase 96 317 1.0E-14 T 01-11-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 SUPERFAMILY SSF53335 25 318 1.46E-43 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 Gene3D G3DSA:3.40.50.150 86 328 3.4E-50 T 01-11-2018 MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 PIRSF PIRSF026567 1 328 8.8E-145 T 01-11-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 120 134 1.3E-6 T 01-11-2018 MLA2C4_24100 b4a1f3a80cd64b043bb5c01e78d1e27b 328 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 217 241 1.3E-6 T 01-11-2018 MLA2C4_27955 0498c7088cb72ddc9752214bb721a58e 427 Pfam PF00860 Permease family 2 386 2.2E-58 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 Gene3D G3DSA:1.10.10.10 3 152 1.8E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 103 - T 01-11-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 SMART SM00347 31 130 4.3E-14 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 Pfam PF01047 MarR family 57 93 4.7E-11 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 SUPERFAMILY SSF46785 10 141 6.08E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.7E-9 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.7E-9 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_04250 33c2f9a5df26f7e9b70aaa8512809610 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.7E-9 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_27230 8051a7090bf8cf775e91ac28f5ecd660 272 SUPERFAMILY SSF52266 92 269 7.66E-10 T 01-11-2018 MLA2C4_27230 8051a7090bf8cf775e91ac28f5ecd660 272 PIRSF PIRSF030175 2 272 5.4E-113 T 01-11-2018 IPR016948 Uncharacterised conserved protein UCP030175 MLA2C4_27230 8051a7090bf8cf775e91ac28f5ecd660 272 Gene3D G3DSA:3.40.50.1110 68 269 9.7E-13 T 01-11-2018 IPR036514 SGNH hydrolase superfamily MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 203 225 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 284 295 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 351 360 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 100 111 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 360 371 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 146 162 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 302 329 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 330 345 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00359 B-class P450 signature 163 178 2.8E-55 T 01-11-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00385 P450 superfamily signature 249 266 7.2E-7 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00385 P450 superfamily signature 284 295 7.2E-7 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00385 P450 superfamily signature 351 360 7.2E-7 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 PRINTS PR00385 P450 superfamily signature 360 371 7.2E-7 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 SUPERFAMILY SSF48264 21 411 2.88E-97 T 01-11-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 Gene3D G3DSA:1.10.630.10 8 411 1.4E-132 T 01-11-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 Pfam PF00067 Cytochrome P450 196 380 6.8E-30 T 01-11-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 MLA2C4_14020 abebaa224032cd7058e4cd37e258caad 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 01-11-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 MLA2C4_13845 d81d2ff8d17b34d294b66df9350ed4d2 180 Pfam PF11667 Putative zincin peptidase 54 154 1.3E-16 T 01-11-2018 IPR021683 Putative zincin peptidase MLA2C4_19595 ab5d5af79a73f325781836a4deead17f 303 SUPERFAMILY SSF51735 3 295 2.36E-46 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_19595 ab5d5af79a73f325781836a4deead17f 303 Gene3D G3DSA:3.90.25.10 170 288 1.7E-59 T 01-11-2018 MLA2C4_19595 ab5d5af79a73f325781836a4deead17f 303 Gene3D G3DSA:3.40.50.720 8 281 1.7E-59 T 01-11-2018 MLA2C4_19595 ab5d5af79a73f325781836a4deead17f 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 230 6.6E-40 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_09005 1358b62f6f837bb2123f0f03af0a9ef8 232 Pfam PF03575 Peptidase family S51 3 203 3.7E-58 T 01-11-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 MLA2C4_09005 1358b62f6f837bb2123f0f03af0a9ef8 232 Gene3D G3DSA:3.40.50.880 9 219 1.0E-41 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_09005 1358b62f6f837bb2123f0f03af0a9ef8 232 SUPERFAMILY SSF52317 1 204 2.47E-30 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_20970 19e8434960306746f2d2ea639719100d 280 Gene3D G3DSA:1.10.3720.10 1 267 6.0E-66 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_20970 19e8434960306746f2d2ea639719100d 280 SUPERFAMILY SSF161098 6 280 1.96E-69 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_20970 19e8434960306746f2d2ea639719100d 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 272 5.5E-22 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_28285 2a9df2d9ec9f1e34b02dcd4a8cc9acf2 343 Pfam PF01757 Acyltransferase family 5 325 6.3E-40 T 01-11-2018 IPR002656 Acyltransferase 3 GO:0016747 MLA2C4_11360 b92e6ebad63a3ae1d294cfe92a211f4f 449 PIRSF PIRSF002746 1 449 8.9E-157 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_11360 b92e6ebad63a3ae1d294cfe92a211f4f 449 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 448 4.0E-155 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_11360 b92e6ebad63a3ae1d294cfe92a211f4f 449 Pfam PF02447 GntP family permease 2 447 2.5E-166 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_06165 10096a37579ca73519ff486e523899f4 244 SUPERFAMILY SSF53474 15 152 6.97E-13 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_06165 10096a37579ca73519ff486e523899f4 244 Gene3D G3DSA:3.40.50.1820 14 230 2.6E-9 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12715 93c936500ac6b688fd2c278d16994541 436 Gene3D G3DSA:3.50.50.60 7 398 5.8E-37 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_12715 93c936500ac6b688fd2c278d16994541 436 Pfam PF01593 Flavin containing amine oxidoreductase 13 252 4.7E-22 T 01-11-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MLA2C4_12715 93c936500ac6b688fd2c278d16994541 436 SUPERFAMILY SSF51905 1 421 6.29E-43 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_12715 93c936500ac6b688fd2c278d16994541 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 376 398 6.5E-6 T 01-11-2018 MLA2C4_12715 93c936500ac6b688fd2c278d16994541 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.5E-6 T 01-11-2018 MLA2C4_12715 93c936500ac6b688fd2c278d16994541 436 Gene3D G3DSA:3.90.660.50 83 369 5.8E-37 T 01-11-2018 MLA2C4_27275 647e5fc57ce1f51d10b3cec812966583 508 ProDom PD608212 POLYMERASE O-ANTIGEN MEMBRANE LIPOPOLYSACCHARIDE TRANSMEMBRANE INNER BIOSYNTHESIS WZY 341 432 2.0E-4 T 01-11-2018 MLA2C4_27275 647e5fc57ce1f51d10b3cec812966583 508 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 11 487 7.1E-19 T 01-11-2018 IPR029468 O-antigen polysaccharide polymerase Wzy MLA2C4_27275 647e5fc57ce1f51d10b3cec812966583 508 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 61 467 1.6E-19 T 01-11-2018 MLA2C4_26785 02994f69b024f1e3cd1c34da5f38e10e 181 Gene3D G3DSA:3.40.50.360 1 174 4.0E-48 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_26785 02994f69b024f1e3cd1c34da5f38e10e 181 Pfam PF03358 NADPH-dependent FMN reductase 3 120 8.0E-20 T 01-11-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MLA2C4_26785 02994f69b024f1e3cd1c34da5f38e10e 181 SUPERFAMILY SSF52218 3 169 1.04E-36 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_16840 2b3a7481b170f9a2d424070df393bbd8 101 Pfam PF08803 Putative mono-oxygenase ydhR 4 98 1.1E-40 T 01-11-2018 IPR014910 Putative monooxygenase YdhR MLA2C4_16840 2b3a7481b170f9a2d424070df393bbd8 101 Gene3D G3DSA:3.30.70.100 1 101 1.9E-40 T 01-11-2018 MLA2C4_16840 2b3a7481b170f9a2d424070df393bbd8 101 SUPERFAMILY SSF54909 3 96 5.5E-32 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_02705 cf3eed7eb63d2fa3cb6ff9693096f87c 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 180 3.6E-30 T 01-11-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase MLA2C4_05355 16d28f01fe25e643b563e9963c1bbe7b 67 Pfam PF13220 Protein of unknown function (DUF4028) 1 65 3.1E-44 T 01-11-2018 IPR025106 Protein of unknown function DUF4028 MLA2C4_13445 914fa733602302fbf8c0001b2239b1ff 217 SUPERFAMILY SSF46689 15 83 2.87E-18 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_13445 914fa733602302fbf8c0001b2239b1ff 217 Gene3D G3DSA:1.10.357.10 12 215 2.2E-38 T 01-11-2018 MLA2C4_13445 914fa733602302fbf8c0001b2239b1ff 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.3E-18 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_13445 914fa733602302fbf8c0001b2239b1ff 217 SUPERFAMILY SSF48498 102 215 4.0E-8 T 01-11-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MLA2C4_13445 914fa733602302fbf8c0001b2239b1ff 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 4.9E-12 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_13445 914fa733602302fbf8c0001b2239b1ff 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.9E-12 T 01-11-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MLA2C4_22700 1be21d146ba24ef2138ed34f547f060e 166 Pfam PF07681 DoxX 16 114 2.0E-10 T 01-11-2018 IPR032808 DoxX family MLA2C4_27410 e2fd3e92a2b45763e92b539796052a99 139 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 122 1.1E-34 T 01-11-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27410 e2fd3e92a2b45763e92b539796052a99 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 01-11-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MLA2C4_27410 e2fd3e92a2b45763e92b539796052a99 139 SUPERFAMILY SSF54862 24 125 2.18E-24 T 01-11-2018 MLA2C4_27410 e2fd3e92a2b45763e92b539796052a99 139 Gene3D G3DSA:3.30.70.3270 24 139 7.6E-33 T 01-11-2018 MLA2C4_27410 e2fd3e92a2b45763e92b539796052a99 139 Pfam PF12838 4Fe-4S dicluster domain 45 102 2.4E-10 T 01-11-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MLA2C4_17875 6487e2af6ba388f14aa69da6b9e5235f 85 Pfam PF13124 Protein of unknown function (DUF3963) 44 83 2.0E-23 T 01-11-2018 IPR025011 Protein of unknown function DUF3963 MLA2C4_20425 6a01b35970a24874091009340857b979 256 Pfam PF08478 POTRA domain, FtsQ-type 53 121 7.0E-20 T 01-11-2018 IPR013685 POTRA domain, FtsQ-type MLA2C4_20425 6a01b35970a24874091009340857b979 256 Pfam PF03799 Cell division protein FtsQ 126 240 1.1E-7 T 01-11-2018 IPR005548 Cell division protein FtsQ/DivIB MLA2C4_20425 6a01b35970a24874091009340857b979 256 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 254 32.051 T 01-11-2018 IPR026580 Cell division protein DivIB MLA2C4_20425 6a01b35970a24874091009340857b979 256 Gene3D G3DSA:3.10.20.310 53 119 6.9E-6 T 01-11-2018 MLA2C4_20425 6a01b35970a24874091009340857b979 256 Gene3D G3DSA:3.40.50.10960 120 235 3.9E-36 T 01-11-2018 MLA2C4_07805 d08fcb1c0976b6c8673d49c5323a41b4 192 Gene3D G3DSA:1.10.1760.20 1 186 5.1E-51 T 01-11-2018 MLA2C4_07805 d08fcb1c0976b6c8673d49c5323a41b4 192 Pfam PF12822 ECF transporter, substrate-specific component 9 177 2.2E-22 T 01-11-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 MLA2C4_07805 d08fcb1c0976b6c8673d49c5323a41b4 192 PIRSF PIRSF037778 3 190 2.5E-41 T 01-11-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 MLA2C4_21940 85d81859d78a69228c308cfde747a27d 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 89 5.0E-36 T 01-11-2018 IPR020390 Uncharacterised protein family YqhV MLA2C4_21940 85d81859d78a69228c308cfde747a27d 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 2.0E-27 T 01-11-2018 IPR020390 Uncharacterised protein family YqhV MLA2C4_11555 6dcdc6720fec447ae7f32c797a3f7c96 372 Gene3D G3DSA:1.10.150.130 58 167 3.4E-28 T 01-11-2018 IPR010998 Integrase/recombinase, N-terminal MLA2C4_11555 6dcdc6720fec447ae7f32c797a3f7c96 372 Gene3D G3DSA:1.10.443.10 168 366 1.3E-58 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_11555 6dcdc6720fec447ae7f32c797a3f7c96 372 Pfam PF00589 Phage integrase family 173 352 1.7E-26 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_11555 6dcdc6720fec447ae7f32c797a3f7c96 372 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 66 120 5.1E-17 T 01-11-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MLA2C4_11555 6dcdc6720fec447ae7f32c797a3f7c96 372 SUPERFAMILY SSF56349 64 361 4.12E-72 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_11555 6dcdc6720fec447ae7f32c797a3f7c96 372 Pfam PF14657 Arm DNA-binding domain 11 56 9.3E-9 T 01-11-2018 IPR028259 AP2-like integrase, N-terminal domain MLA2C4_17325 0b05b2af763ca3bdc1baf9e73698ddc8 233 Gene3D G3DSA:1.10.1760.20 56 217 8.4E-21 T 01-11-2018 MLA2C4_17325 0b05b2af763ca3bdc1baf9e73698ddc8 233 Pfam PF07155 ECF-type riboflavin transporter, S component 58 205 3.5E-9 T 01-11-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 MLA2C4_17325 0b05b2af763ca3bdc1baf9e73698ddc8 233 PIRSF PIRSF037395 1 233 1.4E-81 T 01-11-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 MLA2C4_26065 97974a3112806163b93067b865b5697c 100 SUPERFAMILY SSF89957 1 100 1.3E-32 T 01-11-2018 IPR029756 MTH1187/YkoF-like MLA2C4_26065 97974a3112806163b93067b865b5697c 100 Gene3D G3DSA:3.30.70.930 1 100 9.8E-39 T 01-11-2018 IPR029756 MTH1187/YkoF-like MLA2C4_26065 97974a3112806163b93067b865b5697c 100 Pfam PF01910 Thiamine-binding protein 4 97 6.2E-35 T 01-11-2018 IPR002767 Thiamine-binding protein MLA2C4_26065 97974a3112806163b93067b865b5697c 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 100 1.2E-33 T 01-11-2018 IPR002767 Thiamine-binding protein MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 Pfam PF00072 Response regulator receiver domain 4 113 1.1E-23 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 Pfam PF04397 LytTr DNA-binding domain 149 244 2.4E-32 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 SMART SM00850 148 245 3.9E-38 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 Gene3D G3DSA:3.40.50.2300 1 132 5.1E-32 T 01-11-2018 MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 Gene3D G3DSA:2.40.50.40 138 208 6.4E-16 T 01-11-2018 MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 SUPERFAMILY SSF52172 2 139 1.71E-30 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 SMART SM00448 2 113 2.3E-25 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_28180 106e178997669e280d4b70de57cdb9a8 246 Gene3D G3DSA:2.20.25.10 209 246 3.4E-10 T 01-11-2018 MLA2C4_11930 a2b20964168aebea3dbe3cab0f341d79 64 SMART SM00530 4 59 1.7E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_11930 a2b20964168aebea3dbe3cab0f341d79 64 Gene3D G3DSA:1.10.260.40 1 64 2.3E-17 T 01-11-2018 MLA2C4_11930 a2b20964168aebea3dbe3cab0f341d79 64 Pfam PF01381 Helix-turn-helix 8 57 2.0E-13 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_11930 a2b20964168aebea3dbe3cab0f341d79 64 SUPERFAMILY SSF47413 4 63 9.29E-13 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_10385 bbc12ad863880381bcbb2025ca52fc4d 289 Pfam PF09323 Domain of unknown function (DUF1980) 1 193 1.2E-65 T 01-11-2018 IPR015402 Protein of unknown function DUF1980 MLA2C4_10385 bbc12ad863880381bcbb2025ca52fc4d 289 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 283 3.4E-67 T 01-11-2018 IPR015402 Protein of unknown function DUF1980 MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 Gene3D G3DSA:3.60.20.10 2 227 2.0E-32 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 SUPERFAMILY SSF52402 236 609 9.3E-25 T 01-11-2018 MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 SUPERFAMILY SSF56235 1 225 5.89E-28 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 Pfam PF13537 Glutamine amidotransferase domain 58 165 5.3E-19 T 01-11-2018 IPR017932 Glutamine amidotransferase type 2 domain MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 Pfam PF00733 Asparagine synthase 245 565 1.7E-22 T 01-11-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 PIRSF PIRSF001589 1 591 2.3E-47 T 01-11-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 Gene3D G3DSA:3.40.50.620 473 610 2.8E-6 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_19255 8001474b609a8d7f7ff9691a941402fa 645 Gene3D G3DSA:3.40.50.620 231 392 1.5E-22 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 SMART SM00422 1 68 2.2E-7 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 Gene3D G3DSA:1.10.1660.10 1 125 2.5E-18 T 01-11-2018 MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 SUPERFAMILY SSF46955 1 112 8.06E-17 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 Pfam PF13847 Methyltransferase domain 227 331 1.6E-7 T 01-11-2018 IPR025714 Methyltransferase domain MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 SUPERFAMILY SSF53335 195 351 7.91E-16 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 Pfam PF13411 MerR HTH family regulatory protein 1 65 2.1E-8 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_14180 66c26f3de06914ee9580347c2f1e3f3e 407 Gene3D G3DSA:3.40.50.150 183 381 2.9E-14 T 01-11-2018 MLA2C4_20100 dbf5cc8c6be32e618f98786d5d4640b0 110 SUPERFAMILY SSF88659 1 102 2.24E-34 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_20100 dbf5cc8c6be32e618f98786d5d4640b0 110 Gene3D G3DSA:1.10.10.10 1 109 1.3E-37 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_20100 dbf5cc8c6be32e618f98786d5d4640b0 110 Hamap MF_00245 UPF0122 protein . 2 103 22.409 T 01-11-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like MLA2C4_20100 dbf5cc8c6be32e618f98786d5d4640b0 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 101 8.4E-41 T 01-11-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like MLA2C4_06085 07fd2d8703b5c0db9c636b4693fc6343 410 TIGRFAM TIGR00836 amt: ammonium transporter 5 403 1.5E-143 T 01-11-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MLA2C4_06085 07fd2d8703b5c0db9c636b4693fc6343 410 Gene3D G3DSA:1.10.3430.10 1 410 4.1E-152 T 01-11-2018 IPR029020 Ammonium/urea transporter MLA2C4_06085 07fd2d8703b5c0db9c636b4693fc6343 410 SUPERFAMILY SSF111352 2 384 2.09E-128 T 01-11-2018 MLA2C4_06085 07fd2d8703b5c0db9c636b4693fc6343 410 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 01-11-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MLA2C4_06085 07fd2d8703b5c0db9c636b4693fc6343 410 Pfam PF00909 Ammonium Transporter Family 7 403 3.3E-130 T 01-11-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 Pfam PF01037 Lrp/AsnC ligand binding domain 75 133 2.4E-12 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 5.1E-14 T 01-11-2018 MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 SMART SM00344 1 107 6.9E-28 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 SUPERFAMILY SSF46785 2 118 4.9E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 Gene3D G3DSA:1.10.10.10 1 51 9.8E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 Gene3D G3DSA:3.30.70.920 52 135 3.8E-18 T 01-11-2018 MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.2E-11 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.2E-11 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_15180 a5ba16be3945a7616d7b1a24dd18338a 144 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.2E-11 T 01-11-2018 IPR000485 AsnC-type HTH domain GO:0043565 MLA2C4_22580 4484840451979ce20427cfca9f863e42 44 Pfam PF14141 YqzM-like protein 2 43 1.7E-25 T 01-11-2018 IPR025416 YqzM-like protein MLA2C4_10035 1fff2abe7392864cafe39750c12a88e5 333 Gene3D G3DSA:1.10.260.150 56 333 6.4E-86 T 01-11-2018 MLA2C4_10035 1fff2abe7392864cafe39750c12a88e5 333 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 97 245 8.0E-38 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_10035 1fff2abe7392864cafe39750c12a88e5 333 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 244 1.2E-42 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_22280 0cfb5135f8a872c6c4c9b0fa1481a5e0 57 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 1 54 1.0E-12 T 01-11-2018 IPR024490 Protein of unknown function DUF2759 MLA2C4_22280 0cfb5135f8a872c6c4c9b0fa1481a5e0 57 Pfam PF10958 Protein of unknown function (DUF2759) 6 55 5.3E-24 T 01-11-2018 IPR024490 Protein of unknown function DUF2759 MLA2C4_25955 d05eebecddd3bd38d22f7df46de290be 99 SUPERFAMILY SSF52833 3 97 2.15E-16 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_25955 d05eebecddd3bd38d22f7df46de290be 99 Pfam PF00085 Thioredoxin 12 87 4.8E-10 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 MLA2C4_25955 d05eebecddd3bd38d22f7df46de290be 99 Gene3D G3DSA:3.40.30.10 5 99 6.4E-15 T 01-11-2018 MLA2C4_06120 252502be3679ee73afa06ae1fc6e5213 285 Gene3D G3DSA:3.10.50.40 129 224 1.7E-34 T 01-11-2018 MLA2C4_06120 252502be3679ee73afa06ae1fc6e5213 285 SUPERFAMILY SSF54534 123 223 5.36E-31 T 01-11-2018 MLA2C4_06120 252502be3679ee73afa06ae1fc6e5213 285 Pfam PF00639 PPIC-type PPIASE domain 147 223 5.5E-24 T 01-11-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MLA2C4_06120 252502be3679ee73afa06ae1fc6e5213 285 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 281 20.978 T 01-11-2018 IPR023059 Foldase protein PrsA GO:0003755 MLA2C4_06120 252502be3679ee73afa06ae1fc6e5213 285 SUPERFAMILY SSF109998 28 164 5.3E-17 T 01-11-2018 IPR027304 Trigger factor/SurA domain superfamily MLA2C4_06120 252502be3679ee73afa06ae1fc6e5213 285 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 163 184 - T 01-11-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MLA2C4_25785 9efb28e93a27128b4aec2272a872540d 857 Pfam PF12704 MacB-like periplasmic core domain 21 216 2.7E-11 T 01-11-2018 IPR025857 MacB-like periplasmic core domain MLA2C4_25785 9efb28e93a27128b4aec2272a872540d 857 Pfam PF02687 FtsX-like permease family 279 375 1.2E-10 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_25785 9efb28e93a27128b4aec2272a872540d 857 Pfam PF02687 FtsX-like permease family 759 845 7.7E-6 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_04730 dbd35538409a3652737f378b7df43154 205 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 6 200 3.2E-64 T 01-11-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MLA2C4_04730 dbd35538409a3652737f378b7df43154 205 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 5 203 34.258 T 01-11-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MLA2C4_04730 dbd35538409a3652737f378b7df43154 205 SUPERFAMILY SSF50486 3 204 7.85E-67 T 01-11-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MLA2C4_04730 dbd35538409a3652737f378b7df43154 205 Gene3D G3DSA:3.10.300.10 1 205 8.7E-74 T 01-11-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MLA2C4_04730 dbd35538409a3652737f378b7df43154 205 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 4 203 2.8E-63 T 01-11-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MLA2C4_22500 65795a2d7e299d92a96e969a4bcd433e 147 Gene3D G3DSA:1.10.10.410 91 147 2.3E-24 T 01-11-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MLA2C4_22500 65795a2d7e299d92a96e969a4bcd433e 147 SUPERFAMILY SSF89095 1 146 7.32E-43 T 01-11-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MLA2C4_22500 65795a2d7e299d92a96e969a4bcd433e 147 Gene3D G3DSA:1.10.1510.10 1 90 5.0E-29 T 01-11-2018 MLA2C4_22500 65795a2d7e299d92a96e969a4bcd433e 147 Pfam PF09424 Yqey-like protein 6 146 3.3E-54 T 01-11-2018 IPR019004 Uncharacterised protein YqeY/AIM41 MLA2C4_17030 599b89c16ab0a0c89e283ca90d27f4fb 156 Gene3D G3DSA:1.20.120.450 21 150 7.4E-14 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_17030 599b89c16ab0a0c89e283ca90d27f4fb 156 Pfam PF12867 DinB superfamily 25 138 5.7E-9 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_17030 599b89c16ab0a0c89e283ca90d27f4fb 156 SUPERFAMILY SSF109854 19 151 2.2E-17 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_05080 d474d853b19753980336740c46c5738a 275 SUPERFAMILY SSF53335 46 260 1.82E-36 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_05080 d474d853b19753980336740c46c5738a 275 Gene3D G3DSA:3.40.50.150 54 275 5.8E-32 T 01-11-2018 MLA2C4_05080 d474d853b19753980336740c46c5738a 275 Pfam PF13649 Methyltransferase domain 69 163 6.9E-17 T 01-11-2018 MLA2C4_27340 70295caba015d20672b88951d6091921 301 SUPERFAMILY SSF51261 105 215 6.8E-27 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_27340 70295caba015d20672b88951d6091921 301 Pfam PF01551 Peptidase family M23 113 211 1.1E-22 T 01-11-2018 IPR016047 Peptidase M23 MLA2C4_27340 70295caba015d20672b88951d6091921 301 Gene3D G3DSA:2.70.70.10 70 227 5.3E-46 T 01-11-2018 IPR011055 Duplicated hybrid motif MLA2C4_21270 b2cc624ceebb189530c75e6ad767609e 189 Pfam PF14097 Stage V sporulation protein AE1 4 183 9.9E-82 T 01-11-2018 IPR025914 Stage V sporulation protein AE MLA2C4_08080 e113d2489764900760d547f593a5c985 397 SUPERFAMILY SSF81301 5 138 1.85E-40 T 01-11-2018 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Pfam PF01743 Poly A polymerase head domain 21 140 1.9E-33 T 01-11-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Gene3D G3DSA:1.10.3090.10 142 243 1.5E-27 T 01-11-2018 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Gene3D G3DSA:3.30.460.10 1 141 2.3E-51 T 01-11-2018 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 SUPERFAMILY SSF81891 140 394 4.58E-53 T 01-11-2018 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 244 390 1.7E-44 T 01-11-2018 IPR032810 CCA-adding enzyme, C-terminal MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Gene3D G3DSA:1.20.58.560 244 338 3.2E-19 T 01-11-2018 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Hamap MF_01263 CCA-adding enzyme [cca]. 1 395 42.276 T 01-11-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Gene3D G3DSA:1.10.246.80 339 396 2.3E-24 T 01-11-2018 MLA2C4_08080 e113d2489764900760d547f593a5c985 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 168 226 4.0E-16 T 01-11-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MLA2C4_20945 9af71a3190381c4f7ed8b2529a8b1646 249 Pfam PF13152 Protein of unknown function (DUF3967) 201 229 2.5E-13 T 01-11-2018 IPR025052 Domain of unknown function DUF3967 MLA2C4_07665 1510ab9465a6583d1c4864378c4ab6c4 332 Pfam PF01384 Phosphate transporter family 22 320 3.9E-90 T 01-11-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MLA2C4_12940 a40d4316aaba1313ef9d1892514c6830 93 SUPERFAMILY SSF89447 1 51 3.53E-14 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily MLA2C4_12940 a40d4316aaba1313ef9d1892514c6830 93 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 50 9.6E-8 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_12940 a40d4316aaba1313ef9d1892514c6830 93 Gene3D G3DSA:2.10.260.10 1 54 2.3E-24 T 01-11-2018 MLA2C4_12940 a40d4316aaba1313ef9d1892514c6830 93 SMART SM00966 8 51 1.3E-5 T 01-11-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MLA2C4_13940 e6f5eadb4532ccc47000b96417235315 141 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 14 137 1.9E-29 T 01-11-2018 IPR006480 Bacteriophage holin family MLA2C4_13940 e6f5eadb4532ccc47000b96417235315 141 Pfam PF05105 Bacteriophage holin family 18 127 1.6E-36 T 01-11-2018 IPR006480 Bacteriophage holin family MLA2C4_17255 abcc9275041723caaf51cc7f9a9148e1 418 Gene3D G3DSA:3.40.710.10 32 418 2.8E-114 T 01-11-2018 MLA2C4_17255 abcc9275041723caaf51cc7f9a9148e1 418 Pfam PF00144 Beta-lactamase 107 394 5.6E-38 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_17255 abcc9275041723caaf51cc7f9a9148e1 418 SUPERFAMILY SSF56601 45 409 2.39E-80 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 SUPERFAMILY SSF53850 87 289 4.5E-32 T 01-11-2018 MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 SUPERFAMILY SSF46785 1 87 1.82E-23 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.4E-21 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 Gene3D G3DSA:1.10.10.10 1 91 6.0E-29 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 Gene3D G3DSA:3.40.190.290 92 290 2.8E-37 T 01-11-2018 MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_17070 1ad195a440f2697dbcff828825c474d3 290 Pfam PF03466 LysR substrate binding domain 87 289 2.8E-32 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_04615 c02ee37fab338b08574182acd7160220 171 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 1.6E-55 T 01-11-2018 IPR006286 Deglycase PfpI MLA2C4_04615 c02ee37fab338b08574182acd7160220 171 Pfam PF01965 DJ-1/PfpI family 3 167 6.7E-51 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_04615 c02ee37fab338b08574182acd7160220 171 Gene3D G3DSA:3.40.50.880 1 171 5.0E-52 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_04615 c02ee37fab338b08574182acd7160220 171 SUPERFAMILY SSF52317 1 170 7.69E-45 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_13840 7959f6657c12f38d086fac8a8b6c729b 190 Pfam PF13302 Acetyltransferase (GNAT) domain 17 168 3.3E-20 T 01-11-2018 IPR000182 GNAT domain MLA2C4_13840 7959f6657c12f38d086fac8a8b6c729b 190 Gene3D G3DSA:3.40.630.30 9 189 6.2E-34 T 01-11-2018 MLA2C4_13840 7959f6657c12f38d086fac8a8b6c729b 190 SUPERFAMILY SSF55729 11 174 1.76E-28 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12805 d6f9cbd175f186aa9fc287622e153e69 102 Pfam PF01381 Helix-turn-helix 6 58 6.1E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12805 d6f9cbd175f186aa9fc287622e153e69 102 SMART SM00530 5 60 1.3E-10 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12805 d6f9cbd175f186aa9fc287622e153e69 102 Gene3D G3DSA:1.10.260.40 3 62 1.3E-12 T 01-11-2018 MLA2C4_12805 d6f9cbd175f186aa9fc287622e153e69 102 SUPERFAMILY SSF47413 5 62 5.07E-12 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_10990 7c9768192a95b9888574028eda592419 306 Gene3D G3DSA:1.10.150.350 161 285 3.6E-113 T 01-11-2018 MLA2C4_10990 7c9768192a95b9888574028eda592419 306 Gene3D G3DSA:3.40.50.150 31 222 3.6E-113 T 01-11-2018 MLA2C4_10990 7c9768192a95b9888574028eda592419 306 SUPERFAMILY SSF53335 18 166 1.37E-23 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_10990 7c9768192a95b9888574028eda592419 306 Pfam PF13847 Methyltransferase domain 51 164 3.6E-19 T 01-11-2018 IPR025714 Methyltransferase domain MLA2C4_24405 3368abc4d8583781d1c2b60ad003492a 204 Gene3D G3DSA:3.30.1940.10 21 95 7.9E-76 T 01-11-2018 IPR037154 YtpR-like superfamily MLA2C4_24405 3368abc4d8583781d1c2b60ad003492a 204 Pfam PF01588 Putative tRNA binding domain 99 200 1.6E-27 T 01-11-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MLA2C4_24405 3368abc4d8583781d1c2b60ad003492a 204 Gene3D G3DSA:2.40.50.140 8 202 7.9E-76 T 01-11-2018 MLA2C4_24405 3368abc4d8583781d1c2b60ad003492a 204 SUPERFAMILY SSF50249 95 203 2.94E-33 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_24405 3368abc4d8583781d1c2b60ad003492a 204 Pfam PF14794 Domain of unknown function (DUF4479) 27 94 8.3E-26 T 01-11-2018 IPR027855 Domain of unknown function DUF4479 MLA2C4_14510 e4ad0bffda506763e1b06389a1bd80a0 159 Pfam PF06445 GyrI-like small molecule binding domain 1 156 1.3E-32 T 01-11-2018 IPR029442 GyrI-like small molecule binding domain MLA2C4_14510 e4ad0bffda506763e1b06389a1bd80a0 159 Gene3D G3DSA:3.20.80.10 1 159 2.3E-38 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_14510 e4ad0bffda506763e1b06389a1bd80a0 159 SUPERFAMILY SSF55136 1 157 3.66E-29 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_14510 e4ad0bffda506763e1b06389a1bd80a0 159 SMART SM00871 1 156 5.5E-30 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_22650 4cbbbfbdfc5ed40b0ade8dbb3504d857 262 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 259 40.559 T 01-11-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MLA2C4_22650 4cbbbfbdfc5ed40b0ade8dbb3504d857 262 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 257 1.4E-51 T 01-11-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MLA2C4_22650 4cbbbfbdfc5ed40b0ade8dbb3504d857 262 Pfam PF02666 Phosphatidylserine decarboxylase 59 256 1.8E-57 T 01-11-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MLA2C4_17305 ffc5cc29b0ab8a4d3040c441adf94449 129 Pfam PF04434 SWIM zinc finger 51 82 4.6E-6 T 01-11-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 MLA2C4_27020 ee451ebca704c0ccbf38f6434077dab8 341 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 331 3.7E-37 T 01-11-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MLA2C4_02480 712b2e875debb52a992ee766ab6aabe2 920 Gene3D G3DSA:1.25.40.10 28 184 6.0E-10 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_02480 712b2e875debb52a992ee766ab6aabe2 920 SUPERFAMILY SSF52540 375 533 2.0E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02480 712b2e875debb52a992ee766ab6aabe2 920 Gene3D G3DSA:3.40.50.300 382 598 6.8E-11 T 01-11-2018 MLA2C4_02480 712b2e875debb52a992ee766ab6aabe2 920 SUPERFAMILY SSF48452 36 168 3.96E-11 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_01145 f2c6ff3e8de53e9728c53633c5b7f8cf 283 Pfam PF06800 Sugar transport protein 4 280 1.5E-99 T 01-11-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 MLA2C4_01145 f2c6ff3e8de53e9728c53633c5b7f8cf 283 SUPERFAMILY SSF103481 187 278 3.14E-6 T 01-11-2018 MLA2C4_01145 f2c6ff3e8de53e9728c53633c5b7f8cf 283 SUPERFAMILY SSF103481 36 138 5.62E-7 T 01-11-2018 MLA2C4_05905 8671c24c136818ee61eecdff9b1bbfd1 422 Gene3D G3DSA:3.30.2010.10 203 285 1.3E-25 T 01-11-2018 MLA2C4_05905 8671c24c136818ee61eecdff9b1bbfd1 422 Pfam PF01435 Peptidase family M48 208 414 1.3E-35 T 01-11-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MLA2C4_05905 8671c24c136818ee61eecdff9b1bbfd1 422 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 44 203 5.1E-23 T 01-11-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 MLA2C4_25710 d76b5897a83f7cb3942c8232a2a0b2bb 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 2 78 9.0E-38 T 01-11-2018 MLA2C4_25710 d76b5897a83f7cb3942c8232a2a0b2bb 79 Pfam PF07293 Protein of unknown function (DUF1450) 2 76 1.0E-34 T 01-11-2018 IPR009910 Protein of unknown function DUF1450 MLA2C4_25710 d76b5897a83f7cb3942c8232a2a0b2bb 79 Hamap MF_01542 UPF0349 protein . 2 78 29.848 T 01-11-2018 IPR022916 Protein of unknown function UPF0349 MLA2C4_14430 2434db420c474291272583cb732785ff 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 138 154 4.9E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_14430 2434db420c474291272583cb732785ff 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.9E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_14430 2434db420c474291272583cb732785ff 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 4.9E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_14430 2434db420c474291272583cb732785ff 230 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 176 4.9E-11 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_14430 2434db420c474291272583cb732785ff 230 Gene3D G3DSA:1.10.150.240 16 96 1.3E-51 T 01-11-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MLA2C4_14430 2434db420c474291272583cb732785ff 230 Gene3D G3DSA:3.40.50.1000 5 218 1.3E-51 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_14430 2434db420c474291272583cb732785ff 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 194 4.0E-29 T 01-11-2018 MLA2C4_14430 2434db420c474291272583cb732785ff 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 194 7.7E-9 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_14430 2434db420c474291272583cb732785ff 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 189 5.1E-16 T 01-11-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MLA2C4_14430 2434db420c474291272583cb732785ff 230 SUPERFAMILY SSF56784 3 222 4.2E-41 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_04665 90d0602437e865400951841aa97a0f02 232 Gene3D G3DSA:1.10.3720.10 18 229 6.9E-54 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_04665 90d0602437e865400951841aa97a0f02 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 226 1.4E-23 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_04665 90d0602437e865400951841aa97a0f02 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 121 9.2E-33 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MLA2C4_04665 90d0602437e865400951841aa97a0f02 232 SUPERFAMILY SSF161098 25 227 5.49E-46 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_17050 49f6cd6a3efe141e34238681a651010d 451 Gene3D G3DSA:1.20.1250.20 2 205 4.5E-38 T 01-11-2018 MLA2C4_17050 49f6cd6a3efe141e34238681a651010d 451 Gene3D G3DSA:1.20.1250.20 228 433 7.2E-36 T 01-11-2018 MLA2C4_17050 49f6cd6a3efe141e34238681a651010d 451 SUPERFAMILY SSF103473 4 430 5.1E-78 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_17050 49f6cd6a3efe141e34238681a651010d 451 Pfam PF07690 Major Facilitator Superfamily 15 390 1.8E-51 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_24450 202c9bff71a1d4625ed91ecc73daa8d3 265 Pfam PF01636 Phosphotransferase enzyme family 45 230 1.3E-21 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_24450 202c9bff71a1d4625ed91ecc73daa8d3 265 Gene3D G3DSA:3.90.1200.10 80 264 1.3E-24 T 01-11-2018 MLA2C4_24450 202c9bff71a1d4625ed91ecc73daa8d3 265 SUPERFAMILY SSF56112 3 232 5.2E-32 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_23410 771cc0dbed87e97e0002e98a76c8048c 431 Pfam PF00860 Permease family 13 394 3.9E-59 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_18570 b9a486b16ba350fa9a5a8dc7855c82bd 112 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 110 3.1E-7 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18570 b9a486b16ba350fa9a5a8dc7855c82bd 112 SUPERFAMILY SSF54593 2 112 2.15E-18 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18570 b9a486b16ba350fa9a5a8dc7855c82bd 112 Gene3D G3DSA:3.10.180.10 3 112 2.7E-31 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_13670 3cd7a03ced81af1cce00d1e06d38e62f 188 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 145 1.2E-27 T 01-11-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MLA2C4_13670 3cd7a03ced81af1cce00d1e06d38e62f 188 Pfam PF13242 HAD-hyrolase-like 97 174 3.1E-14 T 01-11-2018 MLA2C4_13670 3cd7a03ced81af1cce00d1e06d38e62f 188 SUPERFAMILY SSF56784 1 180 2.71E-35 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_13670 3cd7a03ced81af1cce00d1e06d38e62f 188 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 2 141 1.2E-27 T 01-11-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MLA2C4_13670 3cd7a03ced81af1cce00d1e06d38e62f 188 Gene3D G3DSA:3.40.50.1000 1 181 2.9E-44 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_13670 3cd7a03ced81af1cce00d1e06d38e62f 188 PIRSF PIRSF004682 1 183 5.8E-43 T 01-11-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MLA2C4_16035 140ecc10735058ee56194cbed893e101 303 SUPERFAMILY SSF103481 39 142 9.81E-18 T 01-11-2018 MLA2C4_16035 140ecc10735058ee56194cbed893e101 303 Pfam PF00892 EamA-like transporter family 6 138 2.4E-29 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_16035 140ecc10735058ee56194cbed893e101 303 Pfam PF00892 EamA-like transporter family 153 287 1.0E-22 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_16035 140ecc10735058ee56194cbed893e101 303 SUPERFAMILY SSF103481 198 292 1.57E-15 T 01-11-2018 MLA2C4_18985 7d58cd76cb182b0587610a43d21ce111 315 SUPERFAMILY SSF53335 51 260 5.11E-27 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_18985 7d58cd76cb182b0587610a43d21ce111 315 Gene3D G3DSA:3.40.50.150 43 218 9.2E-26 T 01-11-2018 MLA2C4_18985 7d58cd76cb182b0587610a43d21ce111 315 Pfam PF08241 Methyltransferase domain 97 189 2.4E-17 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_16880 e3269e2fdbf36185ca6677c5f62673db 132 Pfam PF07485 Domain of Unknown Function (DUF1259) 14 130 7.2E-31 T 01-11-2018 IPR011094 Uncharacterised protein family, LppY/LpqO MLA2C4_13700 7dd3a42c2618af3b0d0254f4c775acf0 264 Gene3D G3DSA:3.10.180.10 3 221 4.5E-35 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_13700 7dd3a42c2618af3b0d0254f4c775acf0 264 SUPERFAMILY SSF54593 2 119 4.07E-10 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15340 7a39b02f0edce5926c68cb3a869ffe94 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 01-11-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MLA2C4_15340 7a39b02f0edce5926c68cb3a869ffe94 399 Gene3D G3DSA:3.40.640.10 44 284 4.1E-116 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_15340 7a39b02f0edce5926c68cb3a869ffe94 399 Pfam PF00155 Aminotransferase class I and II 33 382 4.0E-61 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_15340 7a39b02f0edce5926c68cb3a869ffe94 399 SUPERFAMILY SSF53383 5 384 1.38E-105 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_15340 7a39b02f0edce5926c68cb3a869ffe94 399 Gene3D G3DSA:3.90.1150.10 25 382 4.1E-116 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 Pfam PF00395 S-layer homology domain 532 567 6.2E-6 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 Pfam PF00395 S-layer homology domain 407 446 8.5E-8 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 Pfam PF00395 S-layer homology domain 461 504 1.7E-6 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 248 368 8.6E-25 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 SMART SM00644 238 384 2.0E-26 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 SUPERFAMILY SSF55846 230 386 3.14E-45 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_04745 b93e2afe4cdfa831c230dcdd89b7a243 579 Gene3D G3DSA:3.40.80.10 224 384 4.4E-48 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_19275 4da7ec03b02e8b45e4999f9a81e86036 201 Pfam PF02397 Bacterial sugar transferase 2 176 1.3E-64 T 01-11-2018 IPR003362 Bacterial sugar transferase MLA2C4_07090 8ef01720251d01ae2c81032541e252f5 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 560 1.9E-252 T 01-11-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related MLA2C4_07090 8ef01720251d01ae2c81032541e252f5 564 SUPERFAMILY SSF55486 33 558 5.86E-125 T 01-11-2018 MLA2C4_07090 8ef01720251d01ae2c81032541e252f5 564 Gene3D G3DSA:1.10.1370.30 1 564 2.9E-235 T 01-11-2018 MLA2C4_05195 2e31efb1cc443147fa13ced6abc41c49 168 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 140 6.0E-31 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_05195 2e31efb1cc443147fa13ced6abc41c49 168 Pfam PF02082 Transcriptional regulator 1 83 5.9E-27 T 01-11-2018 IPR000944 Transcription regulator Rrf2-type MLA2C4_05195 2e31efb1cc443147fa13ced6abc41c49 168 SUPERFAMILY SSF46785 3 145 6.12E-31 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05195 2e31efb1cc443147fa13ced6abc41c49 168 Gene3D G3DSA:1.10.10.10 1 149 1.9E-34 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 Gene3D G3DSA:3.40.50.1820 26 287 8.7E-52 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 Pfam PF00561 alpha/beta hydrolase fold 198 273 1.8E-6 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 Pfam PF00561 alpha/beta hydrolase fold 65 166 6.6E-25 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 SUPERFAMILY SSF53474 43 287 4.96E-54 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 105 3.3E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 3.3E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_22695 79fa7518f2a34f284c182be32726dbe0 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 3.3E-8 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 Gene3D G3DSA:3.40.50.720 4 260 7.2E-75 T 01-11-2018 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 2.0E-120 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.0E-8 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.0E-8 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.0E-8 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 258 5.4E-58 T 01-11-2018 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 SUPERFAMILY SSF51735 7 259 2.57E-73 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 4.7E-61 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 4.7E-61 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 4.7E-61 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 4.7E-61 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 4.7E-61 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_12190 152ac58d001a7c38e73c94f83e5f92a8 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 4.7E-61 T 01-11-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 MLA2C4_09270 0807fce95c64125a8f17e6b2ef8eebdd 314 SUPERFAMILY SSF161098 72 300 6.15E-66 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_09270 0807fce95c64125a8f17e6b2ef8eebdd 314 Gene3D G3DSA:1.10.3720.10 68 311 1.9E-77 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_09270 0807fce95c64125a8f17e6b2ef8eebdd 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 308 3.1E-19 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 8.4E-136 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 9.2E-58 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 9.2E-58 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 9.2E-58 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 9.2E-58 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 9.2E-58 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 Gene3D G3DSA:3.30.420.40 6 319 1.7E-125 T 01-11-2018 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 Pfam PF06723 MreB/Mbl protein 4 327 5.1E-148 T 01-11-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 Gene3D G3DSA:3.90.640.10 178 251 1.7E-125 T 01-11-2018 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 SUPERFAMILY SSF53067 3 140 5.48E-39 T 01-11-2018 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 SUPERFAMILY SSF53067 143 325 7.78E-47 T 01-11-2018 MLA2C4_27325 cbdfb9232fb079a247095ab14642c890 333 Gene3D G3DSA:3.30.420.40 146 309 1.7E-125 T 01-11-2018 MLA2C4_02285 d63ecfe6c69adf98556b1f39858f4f36 311 SUPERFAMILY SSF53474 118 305 1.52E-16 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_02285 d63ecfe6c69adf98556b1f39858f4f36 311 Gene3D G3DSA:3.40.50.1820 113 310 4.1E-11 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_06380 f6330a4e14aa734bf1117061dfab23d7 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 1.5E-66 T 01-11-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MLA2C4_06380 f6330a4e14aa734bf1117061dfab23d7 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 176 8.0E-100 T 01-11-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MLA2C4_06380 f6330a4e14aa734bf1117061dfab23d7 181 SUPERFAMILY SSF51182 1 179 1.88E-71 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_06380 f6330a4e14aa734bf1117061dfab23d7 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 176 2.3E-68 T 01-11-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MLA2C4_06380 f6330a4e14aa734bf1117061dfab23d7 181 Gene3D G3DSA:2.60.120.10 1 181 8.9E-72 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_13400 0310998be8d1db6e11ffb30c98076b46 360 Pfam PF03845 Spore germination protein 9 325 5.5E-81 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_13400 0310998be8d1db6e11ffb30c98076b46 360 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 351 9.6E-49 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_11840 3c7751077e49f3e493723520151ce986 149 SUPERFAMILY SSF69279 14 148 8.33E-24 T 01-11-2018 MLA2C4_11840 3c7751077e49f3e493723520151ce986 149 Gene3D G3DSA:2.30.110.40 10 149 1.4E-32 T 01-11-2018 IPR038628 XkdM-like superfamily MLA2C4_11840 3c7751077e49f3e493723520151ce986 149 Pfam PF09393 Phage tail tube protein 12 148 1.1E-28 T 01-11-2018 IPR018989 Phage tail tube protein MLA2C4_02965 9190b6e6874be04ff8cd358f366ed0e4 288 Gene3D G3DSA:3.40.630.30 148 288 1.5E-22 T 01-11-2018 MLA2C4_02965 9190b6e6874be04ff8cd358f366ed0e4 288 Pfam PF00583 Acetyltransferase (GNAT) family 182 276 4.4E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_02965 9190b6e6874be04ff8cd358f366ed0e4 288 SUPERFAMILY SSF55729 156 285 6.18E-20 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_19050 0925074c35f0b8e6bf69de4f26273084 302 SUPERFAMILY SSF103481 191 280 4.32E-8 T 01-11-2018 MLA2C4_19050 0925074c35f0b8e6bf69de4f26273084 302 Pfam PF00892 EamA-like transporter family 5 135 5.0E-9 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_19050 0925074c35f0b8e6bf69de4f26273084 302 Pfam PF00892 EamA-like transporter family 148 279 2.2E-12 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_24665 85a5e51b9c016984f0f2ecba73fa03f3 188 Pfam PF00589 Phage integrase family 11 172 3.2E-16 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_24665 85a5e51b9c016984f0f2ecba73fa03f3 188 Gene3D G3DSA:1.10.443.10 4 186 5.0E-23 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_24665 85a5e51b9c016984f0f2ecba73fa03f3 188 SUPERFAMILY SSF56349 9 179 9.71E-27 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_18180 1f43a9c08ae7dadc18aed570b9859a14 225 Pfam PF02698 DUF218 domain 35 172 8.8E-14 T 01-11-2018 IPR003848 Domain of unknown function DUF218 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 SUPERFAMILY SSF48179 161 268 1.46E-38 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 PIRSF PIRSF000193 2 269 2.0E-84 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 4.6E-18 T 01-11-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 4.4E-40 T 01-11-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.106 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 Gene3D G3DSA:3.40.50.720 1 163 2.2E-51 T 01-11-2018 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 3.4E-86 T 01-11-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 SUPERFAMILY SSF51735 3 159 3.55E-34 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_15745 0e182b8841b2eb5c4eb26a52d102c52c 272 Gene3D G3DSA:1.10.3730.10 164 271 2.3E-39 T 01-11-2018 MLA2C4_04880 0eba0e58e0774df80206459ef50d6e2f 325 PIRSF PIRSF001439 1 325 5.6E-91 T 01-11-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MLA2C4_04880 0eba0e58e0774df80206459ef50d6e2f 325 Gene3D G3DSA:3.30.1780.10 5 319 4.4E-101 T 01-11-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 MLA2C4_04880 0eba0e58e0774df80206459ef50d6e2f 325 Gene3D G3DSA:3.40.50.720 124 298 4.4E-101 T 01-11-2018 MLA2C4_04880 0eba0e58e0774df80206459ef50d6e2f 325 SUPERFAMILY SSF51735 2 325 7.42E-95 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_04880 0eba0e58e0774df80206459ef50d6e2f 325 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 5 317 7.7E-85 T 01-11-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 01-11-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 SUPERFAMILY SSF55174 16 102 9.59E-16 T 01-11-2018 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 Pfam PF00849 RNA pseudouridylate synthase 89 242 7.4E-36 T 01-11-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 Gene3D G3DSA:3.30.2350.10 81 302 1.0E-76 T 01-11-2018 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 301 1.4E-107 T 01-11-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 Pfam PF01479 S4 domain 16 62 2.3E-13 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 Gene3D G3DSA:3.10.290.10 4 71 1.4E-21 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 SMART SM00363 16 75 1.5E-10 T 01-11-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_20345 99c0f45b40d5c36f3562da20c6aa9a91 302 SUPERFAMILY SSF55120 75 301 1.34E-79 T 01-11-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MLA2C4_00060 ef2b014ce59b7595884f16e50d068cd0 333 Pfam PF14175 YaaC-like Protein 10 321 5.2E-111 T 01-11-2018 IPR026988 YaaC-like protein MLA2C4_02980 37c5947d848ae890bdf7954a95186aea 182 Gene3D G3DSA:2.40.50.140 95 174 1.3E-21 T 01-11-2018 MLA2C4_21370 af2971eb2aba2a2ed3f42ae91060f3de 429 Pfam PF00860 Permease family 20 387 8.6E-33 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_02490 6426335f46bb6294644d07cac5165e96 142 Pfam PF00892 EamA-like transporter family 3 140 1.8E-21 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_02490 6426335f46bb6294644d07cac5165e96 142 SUPERFAMILY SSF103481 38 141 7.72E-14 T 01-11-2018 MLA2C4_15710 f0061a8a4f0058a942417a7da33b5985 234 SUPERFAMILY SSF81301 7 118 6.04E-18 T 01-11-2018 MLA2C4_15710 f0061a8a4f0058a942417a7da33b5985 234 Gene3D G3DSA:3.30.460.10 3 119 4.1E-16 T 01-11-2018 MLA2C4_15710 f0061a8a4f0058a942417a7da33b5985 234 Pfam PF01909 Nucleotidyltransferase domain 23 77 1.4E-5 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MLA2C4_07835 09a319e34ecbec4fac7636c2cdde2737 258 SUPERFAMILY SSF56300 43 257 7.47E-29 T 01-11-2018 MLA2C4_07835 09a319e34ecbec4fac7636c2cdde2737 258 Gene3D G3DSA:3.60.21.10 45 228 2.6E-20 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_07835 09a319e34ecbec4fac7636c2cdde2737 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 48 207 6.1E-11 T 01-11-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 MLA2C4_11145 4dd3d85fdce3a6a98afb6890683ce730 236 Gene3D G3DSA:3.40.50.300 2 222 2.6E-46 T 01-11-2018 MLA2C4_11145 4dd3d85fdce3a6a98afb6890683ce730 236 SMART SM00382 27 201 4.5E-5 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_11145 4dd3d85fdce3a6a98afb6890683ce730 236 SUPERFAMILY SSF52540 16 212 1.17E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11145 4dd3d85fdce3a6a98afb6890683ce730 236 Pfam PF00005 ABC transporter 19 152 2.9E-22 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 SUPERFAMILY SSF90123 11 328 1.09E-78 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 Gene3D G3DSA:1.20.1560.10 1 326 8.1E-88 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 Pfam PF00005 ABC transporter 359 508 7.0E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 Gene3D G3DSA:3.40.50.300 339 586 7.3E-90 T 01-11-2018 MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 Pfam PF00664 ABC transporter transmembrane region 24 297 1.9E-45 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 SMART SM00382 368 560 4.5E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 SUPERFAMILY SSF52540 336 578 5.73E-87 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19140 dcb87bbdc2d394eb258dcdd067fdbec5 587 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_26830 42d64906c7668d751555c923832b0199 107 Gene3D G3DSA:1.10.760.10 38 107 5.6E-27 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_26830 42d64906c7668d751555c923832b0199 107 PIRSF PIRSF000025 1 107 1.8E-36 T 01-11-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 MLA2C4_26830 42d64906c7668d751555c923832b0199 107 SUPERFAMILY SSF46626 6 106 2.29E-15 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_26830 42d64906c7668d751555c923832b0199 107 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 103 1.3E-11 T 01-11-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_05260 18bdeb81088f54b54c10629881755064 104 Gene3D G3DSA:1.10.10.10 2 104 2.0E-20 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05260 18bdeb81088f54b54c10629881755064 104 SUPERFAMILY SSF46785 6 100 8.0E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05260 18bdeb81088f54b54c10629881755064 104 Pfam PF03551 Transcriptional regulator PadR-like family 18 85 1.2E-15 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 Gene3D G3DSA:3.40.50.720 2 228 1.4E-49 T 01-11-2018 MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 8.8E-5 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 8.8E-5 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.8E-5 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 SUPERFAMILY SSF51735 3 234 4.11E-48 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 5.1E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 5.1E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 5.1E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.1E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.1E-19 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17800 5a998cdad2bd8cb9c26ccb6d8254ecd8 234 Pfam PF00106 short chain dehydrogenase 3 194 2.0E-30 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 Gene3D G3DSA:2.160.20.10 213 482 4.4E-9 T 01-11-2018 IPR012334 Pectin lyase fold MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 Gene3D G3DSA:2.160.20.10 37 192 4.9E-10 T 01-11-2018 IPR012334 Pectin lyase fold MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 439 463 640.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 394 419 6300.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 164 186 830.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 118 153 6400.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 340 366 1.9 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 317 339 69.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SMART SM00710 371 393 230.0 T 01-11-2018 IPR006626 Parallel beta-helix repeat MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 SUPERFAMILY SSF51126 39 488 7.18E-14 T 01-11-2018 IPR011050 Pectin lyase fold/virulence factor MLA2C4_19280 5143c55250a5f16b38eb77f19ba150f2 836 Pfam PF13229 Right handed beta helix region 320 476 5.4E-8 T 01-11-2018 IPR039448 Right handed beta helix domain MLA2C4_13000 17b66faee8b093883661242fd6620cb2 260 Pfam PF06810 Phage minor structural protein GP20 85 201 2.3E-8 T 01-11-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069 MLA2C4_20410 54591a23c13f7058bdde535c5858f580 305 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 297 1.1E-117 T 01-11-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 MLA2C4_20410 54591a23c13f7058bdde535c5858f580 305 PIRSF PIRSF018571 1 299 4.0E-94 T 01-11-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 MLA2C4_20410 54591a23c13f7058bdde535c5858f580 305 Pfam PF03419 Sporulation factor SpoIIGA 2 296 5.3E-88 T 01-11-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 MLA2C4_26590 a066ef7bcd3c0e932c9e45e93e98fa25 342 SUPERFAMILY SSF46785 19 81 7.35E-12 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26590 a066ef7bcd3c0e932c9e45e93e98fa25 342 SUPERFAMILY SSF100950 90 336 1.44E-68 T 01-11-2018 IPR037171 NagB/RpiA transferase-like MLA2C4_26590 a066ef7bcd3c0e932c9e45e93e98fa25 342 Gene3D G3DSA:3.40.50.1360 92 338 5.2E-82 T 01-11-2018 MLA2C4_26590 a066ef7bcd3c0e932c9e45e93e98fa25 342 Pfam PF04198 Putative sugar-binding domain 90 336 5.2E-69 T 01-11-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MLA2C4_26590 a066ef7bcd3c0e932c9e45e93e98fa25 342 Gene3D G3DSA:1.10.10.10 19 91 6.7E-16 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SUPERFAMILY SSF48452 130 269 1.83E-18 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 Gene3D G3DSA:1.25.40.10 1 369 2.7E-96 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SUPERFAMILY SSF48452 223 360 7.28E-6 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SMART SM00028 178 211 71.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SMART SM00028 330 363 430.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SMART SM00028 137 170 26.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SMART SM00028 97 130 480.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_18210 5aa100b9ad495d236182c053bc35200e 370 SMART SM00028 218 251 4.1 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_26200 05797753fc7da69ad45c31fb9778a079 153 SUPERFAMILY SSF141523 27 152 3.14E-30 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_26200 05797753fc7da69ad45c31fb9778a079 153 Gene3D G3DSA:2.40.440.10 14 153 3.3E-38 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_26200 05797753fc7da69ad45c31fb9778a079 153 Pfam PF03734 L,D-transpeptidase catalytic domain 31 152 3.2E-21 T 01-11-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MLA2C4_04445 c752e06beb89d22829f99c7051d47334 93 PIRSF PIRSF029962 1 93 2.9E-47 T 01-11-2018 IPR016941 Uncharacterised conserved protein UCP029962 MLA2C4_04445 c752e06beb89d22829f99c7051d47334 93 Pfam PF06803 Protein of unknown function (DUF1232) 36 71 7.0E-12 T 01-11-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 Gene3D G3DSA:3.40.50.2300 158 285 8.2E-58 T 01-11-2018 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 SMART SM00354 1 71 3.2E-28 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.2E-18 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 Gene3D G3DSA:3.40.50.2300 62 304 8.2E-58 T 01-11-2018 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 Gene3D G3DSA:1.10.260.40 2 59 2.4E-19 T 01-11-2018 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 SUPERFAMILY SSF47413 1 60 3.02E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 309 1.7E-26 T 01-11-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain MLA2C4_27990 88fd1b325efeeb1b0d56aecc751262ff 325 SUPERFAMILY SSF53822 61 325 5.14E-55 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_18690 f72905d4c8b8945668f4897ba0f2434b 137 SMART SM00881 15 107 2.0E-19 T 01-11-2018 IPR003781 CoA-binding GO:0048037 MLA2C4_18690 f72905d4c8b8945668f4897ba0f2434b 137 Gene3D G3DSA:3.40.50.720 1 137 2.4E-39 T 01-11-2018 MLA2C4_18690 f72905d4c8b8945668f4897ba0f2434b 137 SUPERFAMILY SSF51735 9 136 7.38E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_18690 f72905d4c8b8945668f4897ba0f2434b 137 Pfam PF13380 CoA binding domain 19 133 5.3E-38 T 01-11-2018 IPR003781 CoA-binding GO:0048037 MLA2C4_17260 334ef79a47d50c20c036cefd239cf734 262 Pfam PF12679 ABC-2 family transporter protein 5 227 3.8E-7 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_28190 5b021c5f90a2aee90d38d450f3ab3c58 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_28190 5b021c5f90a2aee90d38d450f3ab3c58 432 Pfam PF07690 Major Facilitator Superfamily 27 298 2.3E-42 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_28190 5b021c5f90a2aee90d38d450f3ab3c58 432 SUPERFAMILY SSF103473 15 431 5.62E-88 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 SMART SM00411 1 90 4.5E-47 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 01-11-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 Gene3D G3DSA:4.10.520.10 1 90 1.4E-39 T 01-11-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.6E-35 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 SUPERFAMILY SSF47729 1 90 6.04E-34 T 01-11-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.2E-21 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.2E-21 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_19470 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.2E-21 T 01-11-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MLA2C4_08300 99d74f9080209ac9786570403a7ddb36 241 Pfam PF00690 Cation transporter/ATPase, N-terminus 39 77 2.1E-6 T 01-11-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MLA2C4_08300 99d74f9080209ac9786570403a7ddb36 241 SUPERFAMILY SSF81653 126 231 1.1E-21 T 01-11-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MLA2C4_08300 99d74f9080209ac9786570403a7ddb36 241 Gene3D G3DSA:2.70.150.10 33 237 1.5E-30 T 01-11-2018 MLA2C4_08300 99d74f9080209ac9786570403a7ddb36 241 SUPERFAMILY SSF81665 37 76 1.7E-5 T 01-11-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MLA2C4_08300 99d74f9080209ac9786570403a7ddb36 241 Pfam PF00122 E1-E2 ATPase 125 232 5.4E-22 T 01-11-2018 MLA2C4_20490 858cea9e22f32a75dff66d3b3b384999 157 Gene3D G3DSA:3.40.630.30 2 157 7.6E-47 T 01-11-2018 MLA2C4_20490 858cea9e22f32a75dff66d3b3b384999 157 Hamap MF_00824 Uncharacterized N-acetyltransferase . 3 144 38.707 T 01-11-2018 IPR017274 Putative N-acetyltransferase YlbP MLA2C4_20490 858cea9e22f32a75dff66d3b3b384999 157 Pfam PF00583 Acetyltransferase (GNAT) family 35 105 2.1E-4 T 01-11-2018 IPR000182 GNAT domain MLA2C4_20490 858cea9e22f32a75dff66d3b3b384999 157 SUPERFAMILY SSF55729 31 141 2.19E-10 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_20490 858cea9e22f32a75dff66d3b3b384999 157 PIRSF PIRSF037732 1 157 4.1E-80 T 01-11-2018 IPR017274 Putative N-acetyltransferase YlbP MLA2C4_07255 7bbdffd914539924ee6a2dc68a0cfe15 364 Pfam PF03060 Nitronate monooxygenase 4 345 6.5E-90 T 01-11-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 MLA2C4_07255 7bbdffd914539924ee6a2dc68a0cfe15 364 SUPERFAMILY SSF51412 4 362 5.65E-67 T 01-11-2018 MLA2C4_07255 7bbdffd914539924ee6a2dc68a0cfe15 364 Gene3D G3DSA:3.20.20.70 3 357 7.3E-118 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 6.3E-13 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 Gene3D G3DSA:1.10.10.10 6 80 2.0E-21 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.0E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.0E-5 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 Pfam PF00155 Aminotransferase class I and II 136 455 5.3E-13 T 01-11-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 SMART SM00345 20 79 7.7E-11 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 SUPERFAMILY SSF53383 75 462 2.27E-74 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 SUPERFAMILY SSF46785 9 88 1.04E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_03095 f2efdda3ff67b3567c93da63ea534b38 466 Gene3D G3DSA:3.40.640.10 93 457 2.2E-114 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_26875 bb14d501f59f390d1f9d6b70b42fbd63 104 SUPERFAMILY SSF46785 3 103 6.12E-30 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26875 bb14d501f59f390d1f9d6b70b42fbd63 104 Gene3D G3DSA:1.10.10.10 6 104 1.6E-34 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26875 bb14d501f59f390d1f9d6b70b42fbd63 104 Pfam PF01638 HxlR-like helix-turn-helix 17 103 1.0E-31 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_18445 2042d7710b397ef1b46411206c6f7cd5 92 Pfam PF06196 Protein of unknown function (DUF997) 12 88 2.5E-32 T 01-11-2018 IPR010398 Protein of unknown function DUF997 MLA2C4_18445 2042d7710b397ef1b46411206c6f7cd5 92 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 7 88 4.0E-41 T 01-11-2018 IPR010398 Protein of unknown function DUF997 MLA2C4_03735 9c3928d13ac6f67f49c4ceba24ba5abe 374 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 368 8.5E-110 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_03735 9c3928d13ac6f67f49c4ceba24ba5abe 374 Pfam PF03845 Spore germination protein 13 333 1.8E-57 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_18120 3e3a91226eb69a03aaa75c1375e76264 174 Gene3D G3DSA:3.40.630.30 1 174 7.2E-45 T 01-11-2018 MLA2C4_18120 3e3a91226eb69a03aaa75c1375e76264 174 Pfam PF00583 Acetyltransferase (GNAT) family 26 130 3.1E-10 T 01-11-2018 IPR000182 GNAT domain MLA2C4_18120 3e3a91226eb69a03aaa75c1375e76264 174 SUPERFAMILY SSF55729 1 138 1.83E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12800 ce4aa35df68cfb65af74487caa0ee0a8 112 Pfam PF01381 Helix-turn-helix 7 60 5.6E-14 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12800 ce4aa35df68cfb65af74487caa0ee0a8 112 SUPERFAMILY SSF47413 1 69 1.45E-17 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_12800 ce4aa35df68cfb65af74487caa0ee0a8 112 Gene3D G3DSA:1.10.260.40 1 81 1.5E-19 T 01-11-2018 MLA2C4_12800 ce4aa35df68cfb65af74487caa0ee0a8 112 SMART SM00530 6 61 1.9E-13 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_23610 f5008c7f79dbf2acb3cd7b32e2db2c85 254 SUPERFAMILY SSF63817 21 253 1.06E-88 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_23610 f5008c7f79dbf2acb3cd7b32e2db2c85 254 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 11 246 1.7E-97 T 01-11-2018 IPR009835 Sortase B family MLA2C4_23610 f5008c7f79dbf2acb3cd7b32e2db2c85 254 Gene3D G3DSA:2.40.260.10 33 254 2.6E-82 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_23610 f5008c7f79dbf2acb3cd7b32e2db2c85 254 Pfam PF04203 Sortase family 86 251 4.2E-24 T 01-11-2018 IPR005754 Sortase family MLA2C4_23610 f5008c7f79dbf2acb3cd7b32e2db2c85 254 PIRSF PIRSF030150 7 252 3.1E-106 T 01-11-2018 IPR015986 Sortase B, Firmicutes MLA2C4_12215 272ff8953ed1ba8fb1aded802b7b3e92 74 SUPERFAMILY SSF160582 1 63 7.59E-27 T 01-11-2018 IPR038020 MbtH-like domain superfamily MLA2C4_12215 272ff8953ed1ba8fb1aded802b7b3e92 74 SMART SM00923 3 53 1.3E-27 T 01-11-2018 IPR005153 MbtH-like domain MLA2C4_12215 272ff8953ed1ba8fb1aded802b7b3e92 74 Pfam PF03621 MbtH-like protein 1 52 2.6E-25 T 01-11-2018 IPR005153 MbtH-like domain MLA2C4_12215 272ff8953ed1ba8fb1aded802b7b3e92 74 Gene3D G3DSA:3.90.820.10 1 68 6.2E-28 T 01-11-2018 MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 415 440 1.4E-4 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 261 286 2.5E-5 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 229 2.7E-6 T 01-11-2018 IPR023908 xxxLxxG heptad repeat MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 SUPERFAMILY SSF101967 177 289 2.88E-5 T 01-11-2018 MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 Pfam PF12698 ABC-2 family transporter protein 24 165 3.7E-12 T 01-11-2018 MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 454 657 1.2E-61 T 01-11-2018 IPR017501 Phage infection protein, YhgE, C-terminal MLA2C4_27000 6d1cec1d160ef509daed6489807d236b 666 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 4.9E-67 T 01-11-2018 IPR017500 Phage infection protein, YhgE, N-terminal MLA2C4_21315 33d019bc4b841a28080504881a7026a3 146 SMART SM00387 35 140 3.4E-7 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_21315 33d019bc4b841a28080504881a7026a3 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 35.172 T 01-11-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 MLA2C4_21315 33d019bc4b841a28080504881a7026a3 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 136 7.1E-71 T 01-11-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 MLA2C4_21315 33d019bc4b841a28080504881a7026a3 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 7.3E-23 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_21315 33d019bc4b841a28080504881a7026a3 146 Gene3D G3DSA:3.30.565.10 1 142 1.2E-32 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_21315 33d019bc4b841a28080504881a7026a3 146 SUPERFAMILY SSF55874 28 135 8.25E-23 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_22065 6bfe9c77cafd92788eb0c5709e72a5c2 197 Pfam PF13346 ABC-2 family transporter protein 3 193 1.2E-32 T 01-11-2018 IPR025699 ABC-2 membrane transporter-like MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 Pfam PF00270 DEAD/DEAH box helicase 18 177 1.5E-22 T 01-11-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 348 6.9E-103 T 01-11-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 SUPERFAMILY SSF52540 55 344 2.99E-58 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 SMART SM00487 12 207 8.6E-28 T 01-11-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 01-11-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 SMART SM00490 241 323 3.1E-24 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 Gene3D G3DSA:3.40.50.300 1 197 1.4E-66 T 01-11-2018 MLA2C4_07820 fc962d4dd7e192c87dc1f8448166ba50 509 Pfam PF00271 Helicase conserved C-terminal domain 227 322 1.8E-16 T 01-11-2018 IPR001650 Helicase, C-terminal MLA2C4_10735 98fcf29de621db2f9c2f8d7cbde1c7a4 264 Pfam PF01261 Xylose isomerase-like TIM barrel 20 219 9.8E-15 T 01-11-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MLA2C4_10735 98fcf29de621db2f9c2f8d7cbde1c7a4 264 Gene3D G3DSA:3.20.20.150 2 264 1.8E-40 T 01-11-2018 MLA2C4_10735 98fcf29de621db2f9c2f8d7cbde1c7a4 264 SUPERFAMILY SSF51658 20 262 2.07E-28 T 01-11-2018 IPR036237 Xylose isomerase-like superfamily MLA2C4_21935 031ac1687930ef163cafb8813ecf0886 308 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 138 228 2.9E-4 T 01-11-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MLA2C4_21935 031ac1687930ef163cafb8813ecf0886 308 SMART SM00382 133 282 8.8E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_21935 031ac1687930ef163cafb8813ecf0886 308 SUPERFAMILY SSF52540 27 260 1.62E-18 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_21935 031ac1687930ef163cafb8813ecf0886 308 Gene3D G3DSA:3.40.50.300 115 268 1.1E-21 T 01-11-2018 MLA2C4_21935 031ac1687930ef163cafb8813ecf0886 308 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 26 292 1.9E-122 T 01-11-2018 IPR014217 Sporulation stage III, protein AA MLA2C4_10820 ed0ec9f4bcfc07b2f6f865609f5c053c 297 SMART SM00894 260 296 8.8E-21 T 01-11-2018 IPR008613 Excalibur calcium-binding domain MLA2C4_10820 ed0ec9f4bcfc07b2f6f865609f5c053c 297 Pfam PF05901 Excalibur calcium-binding domain 261 296 1.2E-14 T 01-11-2018 IPR008613 Excalibur calcium-binding domain MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 357 399 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 Gene3D G3DSA:1.10.10.60 300 353 4.5E-16 T 01-11-2018 MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 Gene3D G3DSA:1.10.10.60 354 407 9.7E-18 T 01-11-2018 MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 SUPERFAMILY SSF46689 305 354 5.73E-8 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 SUPERFAMILY SSF46689 357 407 1.39E-13 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 SMART SM00342 320 403 7.8E-32 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_25130 b9d2dbb5ed1e1a8f77f098864de0a8e9 409 Pfam PF12833 Helix-turn-helix domain 326 404 4.2E-21 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Pfam PF00128 Alpha amylase, catalytic domain 173 469 1.6E-81 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Gene3D G3DSA:3.90.400.10 246 299 3.6E-156 T 01-11-2018 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 SMART SM00642 139 497 9.1E-121 T 01-11-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 SUPERFAMILY SSF51011 507 585 1.14E-17 T 01-11-2018 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Gene3D G3DSA:2.60.40.1180 507 586 2.5E-22 T 01-11-2018 IPR013780 Glycosyl hydrolase, all-beta MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Gene3D G3DSA:3.20.20.80 133 499 3.6E-156 T 01-11-2018 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 121 9.5E-48 T 01-11-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Gene3D G3DSA:2.60.40.10 1 125 6.6E-47 T 01-11-2018 IPR013783 Immunoglobulin-like fold MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 SUPERFAMILY SSF51445 68 503 7.86E-123 T 01-11-2018 IPR017853 Glycoside hydrolase superfamily MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 SUPERFAMILY SSF81296 1 116 6.44E-36 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_20985 3ef74266a810d90b7671e620cdf24a38 586 Pfam PF16657 Maltogenic Amylase, C-terminal domain 507 583 6.6E-16 T 01-11-2018 IPR032091 Maltogenic Amylase, C-terminal MLA2C4_20535 e24466ff1a3c6f57030ec818758fa086 188 PIRSF PIRSF004553 1 184 2.5E-50 T 01-11-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MLA2C4_20535 e24466ff1a3c6f57030ec818758fa086 188 SUPERFAMILY SSF53335 1 181 6.97E-50 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_20535 e24466ff1a3c6f57030ec818758fa086 188 Pfam PF03602 Conserved hypothetical protein 95 1 181 3.7E-58 T 01-11-2018 MLA2C4_20535 e24466ff1a3c6f57030ec818758fa086 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MLA2C4_20535 e24466ff1a3c6f57030ec818758fa086 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 7.4E-52 T 01-11-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MLA2C4_20535 e24466ff1a3c6f57030ec818758fa086 188 Gene3D G3DSA:3.40.50.150 1 187 3.2E-56 T 01-11-2018 MLA2C4_19980 7eaf533ed98ef2822a4c6c5651621258 263 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 221 247 - T 01-11-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MLA2C4_19980 7eaf533ed98ef2822a4c6c5651621258 263 Pfam PF01148 Cytidylyltransferase family 2 262 8.2E-71 T 01-11-2018 MLA2C4_11500 c117f2e717b86b97ac3cc43f1ea9b355 90 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 47 6.3E-12 T 01-11-2018 IPR022453 Zinc finger, MqsA-type MLA2C4_11500 c117f2e717b86b97ac3cc43f1ea9b355 90 Pfam PF14122 YokU-like protein, putative antitoxin 2 88 2.4E-44 T 01-11-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU MLA2C4_11500 c117f2e717b86b97ac3cc43f1ea9b355 90 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 2 90 1.7E-49 T 01-11-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 Gene3D G3DSA:1.20.1720.10 21 228 1.1E-44 T 01-11-2018 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 Gene3D G3DSA:1.20.1250.20 274 458 1.5E-17 T 01-11-2018 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 427 6.3E-71 T 01-11-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 Pfam PF07690 Major Facilitator Superfamily 25 416 2.1E-47 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 344 364 8.3E-8 T 01-11-2018 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 84 106 8.3E-8 T 01-11-2018 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 8.3E-8 T 01-11-2018 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 8.3E-8 T 01-11-2018 MLA2C4_05850 2bfab0f64f5057469fbca0e5b97f090a 459 SUPERFAMILY SSF103473 21 458 3.4E-57 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Gene3D G3DSA:2.170.120.30 322 427 7.2E-12 T 01-11-2018 MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Gene3D G3DSA:2.170.120.30 40 142 2.3E-22 T 01-11-2018 MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Gene3D G3DSA:2.170.120.40 143 229 1.9E-10 T 01-11-2018 MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Gene3D G3DSA:2.170.120.40 236 321 2.5E-20 T 01-11-2018 MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Pfam PF07949 YbbR-like protein 52 132 5.5E-10 T 01-11-2018 IPR012505 YbbR-like MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Pfam PF07949 YbbR-like protein 339 416 4.1E-6 T 01-11-2018 IPR012505 YbbR-like MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Pfam PF07949 YbbR-like protein 142 225 3.3E-12 T 01-11-2018 IPR012505 YbbR-like MLA2C4_00960 0c5a23eca165fe66832d43ef40b70c2b 489 Pfam PF07949 YbbR-like protein 240 319 1.1E-16 T 01-11-2018 IPR012505 YbbR-like MLA2C4_27630 587c5eb5ec5eed2f042872f5e1a953e2 122 SUPERFAMILY SSF52172 4 119 2.42E-36 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_27630 587c5eb5ec5eed2f042872f5e1a953e2 122 SMART SM00448 3 114 1.7E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_27630 587c5eb5ec5eed2f042872f5e1a953e2 122 Pfam PF00072 Response regulator receiver domain 5 115 3.8E-30 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_27630 587c5eb5ec5eed2f042872f5e1a953e2 122 Gene3D G3DSA:3.40.50.2300 1 121 2.5E-41 T 01-11-2018 MLA2C4_13635 028a9923c8f2cee9c071599be33fe5fe 304 Pfam PF01636 Phosphotransferase enzyme family 31 233 1.6E-9 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_13635 028a9923c8f2cee9c071599be33fe5fe 304 Gene3D G3DSA:3.90.1200.10 112 285 1.1E-9 T 01-11-2018 MLA2C4_13635 028a9923c8f2cee9c071599be33fe5fe 304 SUPERFAMILY SSF56112 20 265 4.67E-25 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_07205 9ee37d2ddbf7dc55772835e6cd37c0b5 258 Pfam PF12730 ABC-2 family transporter protein 4 182 4.8E-38 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_25670 28336fc8b9ed294fabb9c50fb8719829 293 Pfam PF13730 Helix-turn-helix domain 34 92 8.5E-12 T 01-11-2018 MLA2C4_25670 28336fc8b9ed294fabb9c50fb8719829 293 SUPERFAMILY SSF46785 25 112 4.97E-5 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_25670 28336fc8b9ed294fabb9c50fb8719829 293 Gene3D G3DSA:1.10.10.10 16 133 9.0E-10 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 213 3.7E-28 T 01-11-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 232 36.435 T 01-11-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 Gene3D G3DSA:3.30.950.10 122 236 3.7E-41 T 01-11-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 Gene3D G3DSA:3.40.1010.10 1 121 4.2E-48 T 01-11-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 92 103 - T 01-11-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 PIRSF PIRSF005917 3 291 2.8E-104 T 01-11-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 SUPERFAMILY SSF53790 12 230 1.11E-81 T 01-11-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MLA2C4_00215 82841dcccdcdbcbf465551e015a3b039 291 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 287 4.2E-79 T 01-11-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MLA2C4_15375 283fb395be681667aa828b4b4028ecfc 126 SMART SM00345 15 74 0.0046 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_15375 283fb395be681667aa828b4b4028ecfc 126 SUPERFAMILY SSF46785 8 81 2.44E-14 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_15375 283fb395be681667aa828b4b4028ecfc 126 Gene3D G3DSA:1.10.10.10 10 126 5.4E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15375 283fb395be681667aa828b4b4028ecfc 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 4.7E-7 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_01955 a96e1e36015ca3e31930745eeb39b1ec 360 Pfam PF01522 Polysaccharide deacetylase 195 316 6.1E-16 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_01955 a96e1e36015ca3e31930745eeb39b1ec 360 Gene3D G3DSA:3.20.20.370 142 360 3.5E-64 T 01-11-2018 MLA2C4_01955 a96e1e36015ca3e31930745eeb39b1ec 360 Gene3D G3DSA:2.60.40.3760 45 141 3.2E-44 T 01-11-2018 MLA2C4_01955 a96e1e36015ca3e31930745eeb39b1ec 360 SUPERFAMILY SSF88713 162 332 6.67E-27 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_26445 03a408cba5a1e534603016d2f4d5a377 133 Hamap MF_01048 Protein PsiE [psiE]. 1 133 25.931 T 01-11-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 MLA2C4_26445 03a408cba5a1e534603016d2f4d5a377 133 PIRSF PIRSF029598 1 133 3.0E-50 T 01-11-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 MLA2C4_26445 03a408cba5a1e534603016d2f4d5a377 133 Pfam PF06146 Phosphate-starvation-inducible E 56 120 1.7E-16 T 01-11-2018 IPR020948 Phosphate-starvation-induced PsiE-like MLA2C4_12175 f30e073e830117e29c68b2ab09bcdd48 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 4.3E-24 T 01-11-2018 IPR018690 Protein of unknown function DUF2187 MLA2C4_00815 7807bf09e7b6d20c8768ebdf331c7865 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.431 T 01-11-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00815 7807bf09e7b6d20c8768ebdf331c7865 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 120 2.7E-48 T 01-11-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00815 7807bf09e7b6d20c8768ebdf331c7865 120 Pfam PF01196 Ribosomal protein L17 16 120 1.9E-39 T 01-11-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00815 7807bf09e7b6d20c8768ebdf331c7865 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 01-11-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00815 7807bf09e7b6d20c8768ebdf331c7865 120 Gene3D G3DSA:3.90.1030.10 1 120 6.6E-50 T 01-11-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00815 7807bf09e7b6d20c8768ebdf331c7865 120 SUPERFAMILY SSF64263 2 120 1.57E-44 T 01-11-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_08845 6068db9bcde7d90b44f38f960790f5bd 341 SUPERFAMILY SSF53850 42 336 4.35E-69 T 01-11-2018 MLA2C4_08845 6068db9bcde7d90b44f38f960790f5bd 341 Gene3D G3DSA:3.40.190.10 45 310 8.5E-72 T 01-11-2018 MLA2C4_08845 6068db9bcde7d90b44f38f960790f5bd 341 Pfam PF13343 Bacterial extracellular solute-binding protein 89 327 1.7E-39 T 01-11-2018 MLA2C4_08845 6068db9bcde7d90b44f38f960790f5bd 341 PIRSF PIRSF002825 1 340 4.1E-61 T 01-11-2018 IPR026045 Ferric binding protein MLA2C4_08845 6068db9bcde7d90b44f38f960790f5bd 341 Gene3D G3DSA:3.40.190.10 144 323 8.5E-72 T 01-11-2018 MLA2C4_07020 3c6d0bb8b666cd1521331adbd4b8a641 358 Gene3D G3DSA:3.40.190.10 145 325 2.1E-89 T 01-11-2018 MLA2C4_07020 3c6d0bb8b666cd1521331adbd4b8a641 358 SUPERFAMILY SSF53850 40 348 1.46E-69 T 01-11-2018 MLA2C4_07020 3c6d0bb8b666cd1521331adbd4b8a641 358 PIRSF PIRSF002825 1 351 9.8E-92 T 01-11-2018 IPR026045 Ferric binding protein MLA2C4_07020 3c6d0bb8b666cd1521331adbd4b8a641 358 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 8 355 1.2E-162 T 01-11-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative MLA2C4_07020 3c6d0bb8b666cd1521331adbd4b8a641 358 Gene3D G3DSA:3.40.190.10 44 319 2.1E-89 T 01-11-2018 MLA2C4_07020 3c6d0bb8b666cd1521331adbd4b8a641 358 Pfam PF13343 Bacterial extracellular solute-binding protein 90 334 3.4E-31 T 01-11-2018 MLA2C4_12195 05831b37bcbd90181a8c544b21377590 399 SUPERFAMILY SSF56322 16 392 2.75E-95 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_12195 05831b37bcbd90181a8c544b21377590 399 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 103 389 2.5E-89 T 01-11-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 MLA2C4_12195 05831b37bcbd90181a8c544b21377590 399 Pfam PF00425 chorismate binding enzyme 122 381 9.7E-78 T 01-11-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MLA2C4_12195 05831b37bcbd90181a8c544b21377590 399 Gene3D G3DSA:3.60.120.10 1 399 7.0E-155 T 01-11-2018 IPR005801 ADC synthase GO:0009058 MLA2C4_13245 678b42b5b1ef9e8bc0d2d1ec44a307be 253 Gene3D G3DSA:3.40.50.300 1 250 3.7E-60 T 01-11-2018 MLA2C4_13245 678b42b5b1ef9e8bc0d2d1ec44a307be 253 Pfam PF00005 ABC transporter 25 174 6.8E-30 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_13245 678b42b5b1ef9e8bc0d2d1ec44a307be 253 SMART SM00382 34 222 1.1E-7 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_13245 678b42b5b1ef9e8bc0d2d1ec44a307be 253 SUPERFAMILY SSF52540 4 236 1.89E-62 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_17740 1f91b2d960088f588d95b33050c41bac 140 Gene3D G3DSA:3.40.50.10600 13 135 1.3E-5 T 01-11-2018 IPR038396 SpoIIAA-like superfamily MLA2C4_17740 1f91b2d960088f588d95b33050c41bac 140 SUPERFAMILY SSF52091 19 136 3.92E-11 T 01-11-2018 IPR036513 STAS domain superfamily MLA2C4_11620 05a81c74d6b4a3f2ab94e54c077e19be 514 SUPERFAMILY SSF52540 5 281 1.28E-16 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_11620 05a81c74d6b4a3f2ab94e54c077e19be 514 Gene3D G3DSA:3.40.50.300 4 293 3.9E-23 T 01-11-2018 MLA2C4_12825 e954b9ef80b88aa53bd83fe4bcfc581c 211 SUPERFAMILY SSF52540 12 206 1.03E-11 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12825 e954b9ef80b88aa53bd83fe4bcfc581c 211 Gene3D G3DSA:3.40.50.300 2 210 1.8E-20 T 01-11-2018 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 PRINTS PR00175 Sodium/alanine symporter signature 417 437 4.3E-57 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 PRINTS PR00175 Sodium/alanine symporter signature 204 223 4.3E-57 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 PRINTS PR00175 Sodium/alanine symporter signature 176 194 4.3E-57 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 PRINTS PR00175 Sodium/alanine symporter signature 86 108 4.3E-57 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 PRINTS PR00175 Sodium/alanine symporter signature 354 376 4.3E-57 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 PRINTS PR00175 Sodium/alanine symporter signature 295 313 4.3E-57 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 Pfam PF01235 Sodium:alanine symporter family 50 460 1.0E-159 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03375 cc5169f8498ba98d1fa7d4dd21853900 486 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 448 4.9E-148 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_08175 a0af5e88d19fb714fed2ccb4cfd60e54 166 Pfam PF14179 YppG-like protein 39 164 1.9E-23 T 01-11-2018 IPR025555 YppG-like protein MLA2C4_28320 e477346b3aad0170e55aeb67f6f5b225 61 Pfam PF14116 YyzF-like protein 5 52 9.8E-21 T 01-11-2018 IPR025626 YyzF-like protein MLA2C4_28320 e477346b3aad0170e55aeb67f6f5b225 61 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 4 51 3.2E-20 T 01-11-2018 IPR025626 YyzF-like protein MLA2C4_14870 e4085e7b7373fafbf990ccb296737a5a 115 Gene3D G3DSA:1.10.10.10 1 115 5.7E-30 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14870 e4085e7b7373fafbf990ccb296737a5a 115 SUPERFAMILY SSF46785 9 108 2.25E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_14870 e4085e7b7373fafbf990ccb296737a5a 115 Pfam PF03551 Transcriptional regulator PadR-like family 19 84 2.0E-17 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_11335 1fe9ce4d240b685052e346af086e2121 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 293 2.1E-7 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_11335 1fe9ce4d240b685052e346af086e2121 339 SUPERFAMILY SSF161098 76 237 7.19E-10 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_11335 1fe9ce4d240b685052e346af086e2121 339 Gene3D G3DSA:1.10.3720.10 70 304 5.3E-11 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 SUPERFAMILY SSF48179 174 293 1.39E-28 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 176 293 1.1E-29 T 01-11-2018 IPR013752 Ketopantoate reductase, C-terminal domain MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 147 4.1E-30 T 01-11-2018 IPR013332 Ketopantoate reductase, N-terminal domain MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 Gene3D G3DSA:3.40.50.720 1 173 1.2E-44 T 01-11-2018 MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 Gene3D G3DSA:1.10.1040.10 174 296 5.6E-41 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 SUPERFAMILY SSF51735 3 161 1.07E-23 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_20485 739bbe64dd3727d9440d7f892dc1ac53 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 4 293 5.8E-73 T 01-11-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 554 577 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 532 547 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 509 531 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 673 684 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 584 597 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 721 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 PRINTS PR00868 DNA-polymerase family A (pol I) signature 608 633 1.1E-25 T 01-11-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 Gene3D G3DSA:3.30.70.370 518 793 8.8E-75 T 01-11-2018 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 SUPERFAMILY SSF56672 317 795 6.56E-95 T 01-11-2018 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 SUPERFAMILY SSF53098 58 306 3.41E-14 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 SMART SM00482 540 757 1.6E-46 T 01-11-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 Pfam PF00476 DNA polymerase family A 477 795 1.7E-72 T 01-11-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MLA2C4_12875 5cc4082ea5098e9e0701f7245c384d77 808 Gene3D G3DSA:1.10.150.20 563 712 8.8E-75 T 01-11-2018 MLA2C4_02625 0d8385b713e0349b5fb394155e17b32a 526 Pfam PF00535 Glycosyl transferase family 2 15 122 6.4E-22 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_02625 0d8385b713e0349b5fb394155e17b32a 526 Pfam PF00535 Glycosyl transferase family 2 273 376 2.4E-11 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_02625 0d8385b713e0349b5fb394155e17b32a 526 SUPERFAMILY SSF53448 10 192 1.76E-28 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02625 0d8385b713e0349b5fb394155e17b32a 526 Gene3D G3DSA:3.90.550.10 259 471 9.9E-16 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02625 0d8385b713e0349b5fb394155e17b32a 526 Gene3D G3DSA:3.90.550.10 5 214 9.3E-29 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02625 0d8385b713e0349b5fb394155e17b32a 526 SUPERFAMILY SSF53448 271 431 5.84E-17 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25855 b89c3a36dfacf1db275a12926bed5051 271 PIRSF PIRSF033101 15 271 6.4E-103 T 01-11-2018 IPR011397 Uncharacterised conserved protein UCP033101 MLA2C4_25855 b89c3a36dfacf1db275a12926bed5051 271 Pfam PF10086 Putative membrane peptidase family (DUF2324) 30 247 3.5E-77 T 01-11-2018 IPR011397 Uncharacterised conserved protein UCP033101 MLA2C4_15320 b7d841fe04e6f50b31ac08a28a7211b9 400 Pfam PF05977 Transmembrane secretion effector 9 311 2.5E-14 T 01-11-2018 IPR010290 Transmembrane secretion effector MLA2C4_15320 b7d841fe04e6f50b31ac08a28a7211b9 400 SUPERFAMILY SSF103473 3 391 4.19E-47 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_15320 b7d841fe04e6f50b31ac08a28a7211b9 400 Gene3D G3DSA:1.20.1250.20 2 388 2.2E-38 T 01-11-2018 MLA2C4_08250 07fcd97becd12445d5ae0b983a810c1b 84 Pfam PF13082 Protein of unknown function (DUF3931) 1 66 4.8E-50 T 01-11-2018 IPR025078 Protein of unknown function DUF3931 MLA2C4_04315 14c2137e43c15ef3dc43c74f508d848b 402 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 100 256 1.8E-41 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_04315 14c2137e43c15ef3dc43c74f508d848b 402 Gene3D G3DSA:1.10.260.150 61 389 1.0E-80 T 01-11-2018 MLA2C4_04315 14c2137e43c15ef3dc43c74f508d848b 402 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 100 256 1.4E-34 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_13990 9b2f0b1fc11f86290e1a9c017da79098 138 Pfam PF13160 Protein of unknown function (DUF3995) 12 132 7.2E-35 T 01-11-2018 IPR025058 Protein of unknown function DUF3995 MLA2C4_08915 ce9276de6556bba7b26e8d3de6226777 136 SMART SM00347 16 116 1.5E-17 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_08915 ce9276de6556bba7b26e8d3de6226777 136 Pfam PF01047 MarR family 23 81 5.3E-14 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_08915 ce9276de6556bba7b26e8d3de6226777 136 SUPERFAMILY SSF46785 10 128 9.9E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08915 ce9276de6556bba7b26e8d3de6226777 136 Gene3D G3DSA:1.10.10.10 2 133 1.1E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_14410 698850e85fdd86fa760f447b8a17c9bb 217 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 152 205 6.9E-15 T 01-11-2018 MLA2C4_27035 292d1c5ae78c970e9bba9c4b3a879df0 553 Pfam PF02652 L-lactate permease 17 543 2.3E-214 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MLA2C4_27035 292d1c5ae78c970e9bba9c4b3a879df0 553 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 546 2.0E-224 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 Gene3D G3DSA:3.30.70.360 173 287 1.2E-116 T 01-11-2018 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 Pfam PF01546 Peptidase family M20/M25/M40 67 370 5.4E-28 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 361 2.6E-88 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 SUPERFAMILY SSF53187 4 368 9.82E-67 T 01-11-2018 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 Gene3D G3DSA:3.40.630.10 7 358 1.2E-116 T 01-11-2018 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 62.468 T 01-11-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 Pfam PF07687 Peptidase dimerisation domain 180 269 6.7E-9 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 PIRSF PIRSF005962 1 375 6.9E-104 T 01-11-2018 IPR017439 Amidohydrolase GO:0016787 MLA2C4_20805 82a3b46cbd9bad088fc8728687d94c3b 376 SUPERFAMILY SSF55031 178 283 6.15E-27 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 Pfam PF00483 Nucleotidyl transferase 9 261 1.6E-71 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 360 7.3E-147 T 01-11-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 100 108 - T 01-11-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 SUPERFAMILY SSF51161 234 375 4.4E-15 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 SUPERFAMILY SSF53448 5 342 1.66E-85 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 Gene3D G3DSA:3.90.550.10 1 275 4.4E-94 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 Gene3D G3DSA:2.160.10.10 276 375 1.7E-27 T 01-11-2018 MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 01-11-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MLA2C4_25320 ff0dcecd3f0d0d54a67d81b61c899144 376 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 371 48.742 T 01-11-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MLA2C4_24325 770a944ab21ca4c59a2ae0f8bd0f57b6 185 Pfam PF06103 Bacterial protein of unknown function (DUF948) 22 109 1.4E-27 T 01-11-2018 IPR009293 Uncharacterised protein family UPF0478 MLA2C4_15995 4f3131f0f6f935bad75ee3cc255afe63 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 80 221 2.8E-5 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_15995 4f3131f0f6f935bad75ee3cc255afe63 341 SUPERFAMILY SSF51735 1 318 3.61E-35 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_15995 4f3131f0f6f935bad75ee3cc255afe63 341 Gene3D G3DSA:3.40.50.720 1 266 2.3E-31 T 01-11-2018 MLA2C4_03950 4243695f805650124e116d3330adfdae 67 SUPERFAMILY SSF54285 3 66 1.16E-17 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MLA2C4_03950 4243695f805650124e116d3330adfdae 67 Gene3D G3DSA:3.10.20.30 1 67 2.6E-20 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_03950 4243695f805650124e116d3330adfdae 67 Pfam PF02597 ThiS family 4 67 4.0E-15 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MLA2C4_03950 4243695f805650124e116d3330adfdae 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.3E-23 T 01-11-2018 IPR010035 ThiS, thiamine-biosynthesis MLA2C4_21465 dcf289ee4cefd617699ec131b46f87c7 158 Pfam PF12651 Ribbon-helix-helix domain 106 148 1.5E-11 T 01-11-2018 IPR038733 Predicted DNA-binding protein, ribbon-helix-helix domain MLA2C4_21465 dcf289ee4cefd617699ec131b46f87c7 158 SUPERFAMILY SSF47598 106 146 3.84E-5 T 01-11-2018 IPR010985 Ribbon-helix-helix GO:0006355 MLA2C4_08255 5982bb30a0e82633dc63abe2633654d2 155 Gene3D G3DSA:3.40.630.30 1 155 4.0E-48 T 01-11-2018 MLA2C4_08255 5982bb30a0e82633dc63abe2633654d2 155 Pfam PF00583 Acetyltransferase (GNAT) family 33 116 4.2E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_08255 5982bb30a0e82633dc63abe2633654d2 155 SUPERFAMILY SSF55729 17 150 1.86E-29 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_13590 11824960f03ed975f69e8a77954ce3e0 186 SUPERFAMILY SSF53335 43 153 1.2E-9 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_13590 11824960f03ed975f69e8a77954ce3e0 186 Gene3D G3DSA:3.40.50.150 17 168 2.3E-11 T 01-11-2018 MLA2C4_21450 2d9dec8e33b3ac220e03e0208031ec5a 174 SUPERFAMILY SSF81301 5 168 5.23E-51 T 01-11-2018 MLA2C4_21450 2d9dec8e33b3ac220e03e0208031ec5a 174 Pfam PF04229 GrpB protein 4 162 7.8E-53 T 01-11-2018 IPR007344 GrpB/Dephospho-CoA kinase MLA2C4_21450 2d9dec8e33b3ac220e03e0208031ec5a 174 Gene3D G3DSA:3.30.460.10 1 169 5.8E-55 T 01-11-2018 MLA2C4_01350 2510f1315644b70cc2e09b6ee7f26f67 39 Pfam PF13134 Protein of unknown function (DUF3948) 4 38 4.8E-22 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 SUPERFAMILY SSF51735 1 161 7.71E-41 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 1.9E-44 T 01-11-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 Gene3D G3DSA:3.40.50.720 1 164 1.6E-53 T 01-11-2018 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 PIRSF PIRSF000103 1 294 3.8E-67 T 01-11-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 SUPERFAMILY SSF48179 167 289 1.36E-33 T 01-11-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 Gene3D G3DSA:1.10.1040.10 166 296 7.0E-42 T 01-11-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 285 1.6E-31 T 01-11-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MLA2C4_12130 345e95d12cf4e86b7826b56a003f9025 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 01-11-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 292 1.7E-15 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 Pfam PF00005 ABC transporter 26 183 1.1E-28 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 SUPERFAMILY SSF52540 5 255 5.96E-68 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 SMART SM00382 34 241 3.6E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 Gene3D G3DSA:3.40.50.300 3 336 9.0E-98 T 01-11-2018 MLA2C4_03485 0b695985993a53634617cf427a23b6a3 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 8.9E-23 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_14675 24296d235d51a506449d655c13e10586 218 Pfam PF13315 Protein of unknown function (DUF4085) 3 208 3.5E-75 T 01-11-2018 IPR025144 Protein of unknown function DUF4085 MLA2C4_22285 d80fdbe76be00643b62c8fa7df7420b2 327 SUPERFAMILY SSF53067 5 320 1.25E-71 T 01-11-2018 MLA2C4_22285 d80fdbe76be00643b62c8fa7df7420b2 327 ProSitePatterns PS01125 ROK family signature. 139 166 - T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_22285 d80fdbe76be00643b62c8fa7df7420b2 327 Pfam PF00480 ROK family 7 319 4.4E-79 T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_22285 d80fdbe76be00643b62c8fa7df7420b2 327 Gene3D G3DSA:3.30.420.40 7 315 1.2E-110 T 01-11-2018 MLA2C4_22285 d80fdbe76be00643b62c8fa7df7420b2 327 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 322 4.6E-123 T 01-11-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MLA2C4_22285 d80fdbe76be00643b62c8fa7df7420b2 327 Gene3D G3DSA:3.30.420.40 130 303 1.2E-110 T 01-11-2018 MLA2C4_13805 601f2de7c835f2e72f29251d3d7d1370 304 Pfam PF03069 Acetamidase/Formamidase family 147 277 8.6E-21 T 01-11-2018 IPR004304 Acetamidase/Formamidase GO:0016811 MLA2C4_13805 601f2de7c835f2e72f29251d3d7d1370 304 Pfam PF03069 Acetamidase/Formamidase family 14 141 3.1E-14 T 01-11-2018 IPR004304 Acetamidase/Formamidase GO:0016811 MLA2C4_13805 601f2de7c835f2e72f29251d3d7d1370 304 Gene3D G3DSA:2.60.120.580 21 208 2.5E-64 T 01-11-2018 MLA2C4_13805 601f2de7c835f2e72f29251d3d7d1370 304 Gene3D G3DSA:2.40.10.120 84 127 2.5E-64 T 01-11-2018 MLA2C4_13805 601f2de7c835f2e72f29251d3d7d1370 304 SUPERFAMILY SSF141130 2 291 8.63E-89 T 01-11-2018 MLA2C4_13805 601f2de7c835f2e72f29251d3d7d1370 304 Gene3D G3DSA:3.10.28.20 214 292 1.4E-20 T 01-11-2018 MLA2C4_12920 e4c67f1f4283282802d08186c72f4a2a 105 Gene3D G3DSA:3.30.160.550 2 54 8.6E-6 T 01-11-2018 MLA2C4_26370 6384100702945f025fc9589965b87231 115 Pfam PF01638 HxlR-like helix-turn-helix 14 102 1.2E-39 T 01-11-2018 IPR002577 Helix-turn-helix, HxlR type MLA2C4_26370 6384100702945f025fc9589965b87231 115 SUPERFAMILY SSF46785 2 105 1.52E-34 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26370 6384100702945f025fc9589965b87231 115 Gene3D G3DSA:1.10.10.10 1 115 5.3E-41 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_01125 5f7005ff4a31defe44e937bb138e047c 546 Gene3D G3DSA:3.40.190.10 55 534 9.8E-176 T 01-11-2018 MLA2C4_01125 5f7005ff4a31defe44e937bb138e047c 546 SUPERFAMILY SSF53850 34 541 1.52E-120 T 01-11-2018 MLA2C4_01125 5f7005ff4a31defe44e937bb138e047c 546 Gene3D G3DSA:3.90.76.10 74 195 9.8E-176 T 01-11-2018 MLA2C4_01125 5f7005ff4a31defe44e937bb138e047c 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 465 3.1E-75 T 01-11-2018 IPR000914 Solute-binding protein family 5 domain MLA2C4_01125 5f7005ff4a31defe44e937bb138e047c 546 PIRSF PIRSF002741 1 546 1.2E-104 T 01-11-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MLA2C4_01125 5f7005ff4a31defe44e937bb138e047c 546 Gene3D G3DSA:3.10.105.10 295 517 9.8E-176 T 01-11-2018 MLA2C4_02760 8030feac3253cef3117e0568c132b8e3 337 SUPERFAMILY SSF52540 35 252 2.21E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02760 8030feac3253cef3117e0568c132b8e3 337 SMART SM00382 50 234 7.0E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_02760 8030feac3253cef3117e0568c132b8e3 337 Gene3D G3DSA:3.40.50.300 26 270 7.9E-60 T 01-11-2018 MLA2C4_02760 8030feac3253cef3117e0568c132b8e3 337 Pfam PF00005 ABC transporter 42 185 5.9E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_18905 52d09205399f903c47563ed7bb05ecad 150 SMART SM00701 1 129 6.7E-8 T 01-11-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_18905 52d09205399f903c47563ed7bb05ecad 150 SMART SM00644 9 137 6.0E-11 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_18905 52d09205399f903c47563ed7bb05ecad 150 Gene3D G3DSA:3.40.80.10 10 148 1.1E-38 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_18905 52d09205399f903c47563ed7bb05ecad 150 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 18 137 1.5E-25 T 01-11-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_18905 52d09205399f903c47563ed7bb05ecad 150 SUPERFAMILY SSF55846 14 140 4.71E-36 T 01-11-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 1.1E-137 T 01-11-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 01-11-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 SUPERFAMILY SSF53686 1 304 3.01E-106 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 Gene3D G3DSA:3.40.50.1100 45 143 6.9E-127 T 01-11-2018 MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 291 1.1E-71 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 5.5E-147 T 01-11-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MLA2C4_00385 afc904d525888811392906ad300cb7f9 307 Gene3D G3DSA:3.40.50.1100 6 299 6.9E-127 T 01-11-2018 MLA2C4_03010 559b2e3ba1fe01fec9b7aaa2b611ba8d 84 Gene3D G3DSA:2.40.50.100 1 77 3.4E-7 T 01-11-2018 MLA2C4_26675 81109cc4a617f193e766470d3bb06510 268 Pfam PF04018 Domain of unknown function (DUF368) 12 239 1.6E-53 T 01-11-2018 IPR007163 Protein of unknown function DUF368 MLA2C4_01085 9ab5408778dd1ba6a57e6c0cbd27c88b 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 81 2.9E-8 T 01-11-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MLA2C4_01085 9ab5408778dd1ba6a57e6c0cbd27c88b 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 312 2.7E-27 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_01085 9ab5408778dd1ba6a57e6c0cbd27c88b 334 Gene3D G3DSA:1.10.3720.10 93 313 2.1E-19 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01085 9ab5408778dd1ba6a57e6c0cbd27c88b 334 SUPERFAMILY SSF161098 98 295 3.79E-22 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_27255 ab1cfa078230c141d062e6bef18bf580 411 Pfam PF00534 Glycosyl transferases group 1 220 388 9.4E-9 T 01-11-2018 IPR001296 Glycosyl transferase, family 1 MLA2C4_27255 ab1cfa078230c141d062e6bef18bf580 411 Gene3D G3DSA:3.40.50.2000 1 211 1.3E-12 T 01-11-2018 MLA2C4_27255 ab1cfa078230c141d062e6bef18bf580 411 Gene3D G3DSA:3.40.50.2000 212 395 2.5E-18 T 01-11-2018 MLA2C4_27255 ab1cfa078230c141d062e6bef18bf580 411 SUPERFAMILY SSF53756 4 410 1.26E-33 T 01-11-2018 MLA2C4_05265 02a609e467817e0f996a3f47e94b0498 203 Pfam PF11193 Protein of unknown function (DUF2812) 10 118 2.3E-30 T 01-11-2018 IPR021359 Protein of unknown function DUF2812 MLA2C4_16900 439f51eae4a8c78a7c7261375427d24c 110 Gene3D G3DSA:3.30.429.10 1 108 6.5E-38 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily MLA2C4_16900 439f51eae4a8c78a7c7261375427d24c 110 Pfam PF08921 Domain of unknown function (DUF1904) 1 107 1.5E-31 T 01-11-2018 IPR015017 Protein of unknown function DUF1904 MLA2C4_16900 439f51eae4a8c78a7c7261375427d24c 110 SUPERFAMILY SSF55331 1 108 3.66E-35 T 01-11-2018 IPR014347 Tautomerase/MIF superfamily MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Gene3D G3DSA:2.40.110.10 152 257 2.4E-33 T 01-11-2018 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 259 421 1.3E-35 T 01-11-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 SUPERFAMILY SSF56645 28 269 2.09E-70 T 01-11-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Gene3D G3DSA:1.10.540.10 5 151 7.5E-48 T 01-11-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 384 403 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Gene3D G3DSA:1.20.140.10 429 600 1.2E-60 T 01-11-2018 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 155 167 - T 01-11-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Gene3D G3DSA:1.20.140.10 258 428 9.0E-54 T 01-11-2018 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 SUPERFAMILY SSF47203 263 428 3.38E-45 T 01-11-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 153 245 1.9E-20 T 01-11-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MLA2C4_26030 9d5687baf7dc464bfe63f6ab3d4c0d2e 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 149 4.1E-29 T 01-11-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MLA2C4_15410 357226046d5cc116627fd6aaad070893 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 4.2E-24 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_15410 357226046d5cc116627fd6aaad070893 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 4.1E-21 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_08155 b39a20f84bb3df1fd036d8e46563d2dd 341 Pfam PF10720 Protein of unknown function (DUF2515) 28 328 2.7E-127 T 01-11-2018 IPR019658 Protein of unknown function DUF2515 MLA2C4_15310 4ff2587503d2a5194c7175a1bfad382d 50 SUPERFAMILY SSF160059 1 48 7.85E-19 T 01-11-2018 MLA2C4_15310 4ff2587503d2a5194c7175a1bfad382d 50 Pfam PF14553 YqbF, hypothetical protein domain 7 47 1.2E-16 T 01-11-2018 IPR027926 Uncharacterised protein YqbF domain MLA2C4_15310 4ff2587503d2a5194c7175a1bfad382d 50 Gene3D G3DSA:3.40.5.20 1 46 2.3E-10 T 01-11-2018 IPR036840 YqbF domain superfamily MLA2C4_25680 b5ae6f1a7f74ce62acc0023e93c0902d 117 Gene3D G3DSA:2.40.50.480 21 117 3.9E-40 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_25680 b5ae6f1a7f74ce62acc0023e93c0902d 117 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 4 114 6.0E-23 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_25680 b5ae6f1a7f74ce62acc0023e93c0902d 117 SUPERFAMILY SSF159121 24 115 4.84E-31 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_25680 b5ae6f1a7f74ce62acc0023e93c0902d 117 Pfam PF06486 Protein of unknown function (DUF1093) 24 104 7.2E-27 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_07495 ee995073dd0185dc5d369fba288ef947 149 Pfam PF13027 Protein of unknown function (DUF3888) 49 132 1.1E-19 T 01-11-2018 IPR024984 Protein of unknown function DUF3888 MLA2C4_01095 674a4312e4e28153dbcab163b5d54dbb 257 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 255 2.8E-6 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_01095 674a4312e4e28153dbcab163b5d54dbb 257 SUPERFAMILY SSF52540 5 248 3.97E-72 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01095 674a4312e4e28153dbcab163b5d54dbb 257 Gene3D G3DSA:3.40.50.300 3 257 7.4E-85 T 01-11-2018 MLA2C4_01095 674a4312e4e28153dbcab163b5d54dbb 257 Pfam PF00005 ABC transporter 25 176 1.4E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01095 674a4312e4e28153dbcab163b5d54dbb 257 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01095 674a4312e4e28153dbcab163b5d54dbb 257 SMART SM00382 34 225 1.1E-13 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_21100 7a7323bd75d446da514de8019be152de 287 SUPERFAMILY SSF56317 27 286 1.11E-75 T 01-11-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MLA2C4_21100 7a7323bd75d446da514de8019be152de 287 Gene3D G3DSA:3.60.110.10 11 287 2.7E-94 T 01-11-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MLA2C4_21100 7a7323bd75d446da514de8019be152de 287 Pfam PF00795 Carbon-nitrogen hydrolase 30 273 2.2E-50 T 01-11-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 Gene3D G3DSA:3.40.50.2300 1 128 3.1E-44 T 01-11-2018 MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 SMART SM00862 148 221 5.8E-29 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 1.0E-28 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 Gene3D G3DSA:1.10.10.10 129 223 7.2E-36 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 SMART SM00448 4 114 1.5E-44 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 SUPERFAMILY SSF52172 1 181 1.14E-46 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_06910 4b0646bb66508d0a5ed88039db567265 223 Pfam PF00072 Response regulator receiver domain 6 114 5.6E-32 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_12360 2100f1f5c986a63122d4957887e13a59 231 Pfam PF00027 Cyclic nucleotide-binding domain 33 116 3.3E-16 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_12360 2100f1f5c986a63122d4957887e13a59 231 SUPERFAMILY SSF51206 21 137 3.14E-25 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like MLA2C4_12360 2100f1f5c986a63122d4957887e13a59 231 SUPERFAMILY SSF46785 149 224 2.84E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_12360 2100f1f5c986a63122d4957887e13a59 231 Pfam PF13545 Crp-like helix-turn-helix domain 152 220 5.4E-10 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MLA2C4_12360 2100f1f5c986a63122d4957887e13a59 231 SMART SM00100 9 131 1.4E-11 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_12360 2100f1f5c986a63122d4957887e13a59 231 Gene3D G3DSA:2.60.120.1460 14 225 2.9E-36 T 01-11-2018 MLA2C4_07370 e18edd02b8100ab72cf48614e63d4994 79 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 1.0E-19 T 01-11-2018 IPR005370 Uncharacterised protein family UPF0180 MLA2C4_07370 e18edd02b8100ab72cf48614e63d4994 79 Hamap MF_00506 UPF0180 protein . 1 79 29.446 T 01-11-2018 IPR005370 Uncharacterised protein family UPF0180 MLA2C4_07370 e18edd02b8100ab72cf48614e63d4994 79 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 78 2.2E-31 T 01-11-2018 IPR005370 Uncharacterised protein family UPF0180 MLA2C4_08935 2eb244f13a87b5d33d9d323e63f186aa 368 Pfam PF13786 Domain of unknown function (DUF4179) 44 136 1.6E-18 T 01-11-2018 IPR025436 Domain of unknown function DUF4179 MLA2C4_08935 2eb244f13a87b5d33d9d323e63f186aa 368 Gene3D G3DSA:2.60.40.1630 75 221 2.5E-51 T 01-11-2018 MLA2C4_08935 2eb244f13a87b5d33d9d323e63f186aa 368 Gene3D G3DSA:2.60.40.1640 222 368 1.7E-55 T 01-11-2018 MLA2C4_18355 55632333621f594b33687a5ae8055d68 113 Gene3D G3DSA:1.20.5.340 58 109 1.7E-5 T 01-11-2018 MLA2C4_18355 55632333621f594b33687a5ae8055d68 113 SUPERFAMILY SSF57997 62 103 4.25E-5 T 01-11-2018 MLA2C4_15525 7c9180a90070a2cc33853efe0c2bfaee 224 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 183 1.8E-69 T 01-11-2018 IPR022301 Integral membrane protein YjbE MLA2C4_15525 7c9180a90070a2cc33853efe0c2bfaee 224 Pfam PF03741 Integral membrane protein TerC family 13 182 8.7E-46 T 01-11-2018 IPR005496 Integral membrane protein TerC GO:0016021 MLA2C4_16105 45ff9ea50ed89faa2e6432a8ba15b6c2 101 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 93 3.4E-9 T 01-11-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MLA2C4_16105 45ff9ea50ed89faa2e6432a8ba15b6c2 101 SUPERFAMILY SSF89360 1 99 2.22E-6 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MLA2C4_08500 1dfd0487c02834166fa3351f5265a304 72 Gene3D G3DSA:1.20.58.990 19 72 4.5E-27 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_08500 1dfd0487c02834166fa3351f5265a304 72 Pfam PF09388 Spo0E like sporulation regulatory protein 24 65 2.5E-12 T 01-11-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 MLA2C4_08500 1dfd0487c02834166fa3351f5265a304 72 SUPERFAMILY SSF140500 19 70 1.44E-14 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_25745 cb21403fd8793727ab20bb68b748d635 225 Pfam PF02517 CAAX protease self-immunity 129 216 5.7E-20 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_08960 7ae3081d7cda7ef136ab38327e9a1ef9 321 SUPERFAMILY SSF103481 214 302 1.12E-9 T 01-11-2018 MLA2C4_08960 7ae3081d7cda7ef136ab38327e9a1ef9 321 SUPERFAMILY SSF103481 44 150 2.03E-9 T 01-11-2018 MLA2C4_08960 7ae3081d7cda7ef136ab38327e9a1ef9 321 Pfam PF00892 EamA-like transporter family 161 300 2.9E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_08960 7ae3081d7cda7ef136ab38327e9a1ef9 321 Pfam PF00892 EamA-like transporter family 7 148 3.5E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_04305 b1fe7671cd658cceaf1e8bbbd35350a3 254 Pfam PF01925 Sulfite exporter TauE/SafE 7 247 3.2E-41 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MLA2C4_21300 362a77b8f28ce417d0a6ca73db3cade8 32 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 29 6.2E-9 T 01-11-2018 IPR031596 Putative methionine and alanine importer, small subunit MLA2C4_11530 13c95659d006501d224ff589774b925b 273 Gene3D G3DSA:1.10.510.10 15 266 9.9E-40 T 01-11-2018 MLA2C4_11530 13c95659d006501d224ff589774b925b 273 Pfam PF00069 Protein kinase domain 24 185 6.2E-30 T 01-11-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MLA2C4_11530 13c95659d006501d224ff589774b925b 273 SMART SM00219 24 254 1.5E-4 T 01-11-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 MLA2C4_11530 13c95659d006501d224ff589774b925b 273 SUPERFAMILY SSF56112 12 219 6.61E-45 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_06290 b40395ef5206322edea204dc01977b0a 132 SUPERFAMILY SSF46458 7 124 4.86E-40 T 01-11-2018 IPR009050 Globin-like superfamily MLA2C4_06290 b40395ef5206322edea204dc01977b0a 132 Pfam PF01152 Bacterial-like globin 9 123 6.9E-34 T 01-11-2018 IPR001486 Truncated hemoglobin GO:0019825 MLA2C4_06290 b40395ef5206322edea204dc01977b0a 132 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 01-11-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 MLA2C4_06290 b40395ef5206322edea204dc01977b0a 132 Gene3D G3DSA:1.10.490.10 1 131 9.7E-50 T 01-11-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 2.4E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 2.4E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 2.4E-6 T 01-11-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 SMART SM00387 369 480 8.4E-21 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 Gene3D G3DSA:3.30.565.10 329 480 1.3E-28 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 SMART SM00388 258 324 1.9E-9 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 323 8.6E-9 T 01-11-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 Gene3D G3DSA:1.10.287.130 251 323 1.9E-12 T 01-11-2018 MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 SUPERFAMILY SSF55874 315 478 3.41E-30 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 459 4.0E-14 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_26210 8be01ccc723ea52c21dc412ab46ba24e 480 SUPERFAMILY SSF47384 244 325 8.44E-13 T 01-11-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MLA2C4_17355 a29862ff665cb52243083ca41afcc2fe 476 Pfam PF03606 C4-dicarboxylate anaerobic carrier 18 469 1.1E-86 T 01-11-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 MLA2C4_10810 38ddcda67bfaa659bbebf142a920f876 235 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 231 2.2E-86 T 01-11-2018 IPR019903 Repair of iron centres family MLA2C4_10810 38ddcda67bfaa659bbebf142a920f876 235 Gene3D G3DSA:1.20.120.520 70 235 8.8E-21 T 01-11-2018 MLA2C4_10810 38ddcda67bfaa659bbebf142a920f876 235 Pfam PF01814 Hemerythrin HHE cation binding domain 84 231 1.3E-25 T 01-11-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MLA2C4_10810 38ddcda67bfaa659bbebf142a920f876 235 Pfam PF04405 Domain of Unknown function (DUF542) 9 61 2.3E-21 T 01-11-2018 IPR019903 Repair of iron centres family MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 Gene3D G3DSA:2.40.50.140 2 66 7.4E-30 T 01-11-2018 MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 SUPERFAMILY SSF50249 3 66 6.47E-25 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 01-11-2018 IPR019844 Cold-shock conserved site MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 PIRSF PIRSF002599 1 67 1.4E-24 T 01-11-2018 IPR012156 Cold shock, CspA GO:0003676 MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 SMART SM00357 4 67 9.0E-31 T 01-11-2018 IPR011129 Cold shock domain GO:0003676 MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 3.5E-30 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 PRINTS PR00050 Cold shock protein signature 40 58 2.1E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 PRINTS PR00050 Cold shock protein signature 5 20 2.1E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_12460 92a305f6292909d09542673ebe2c6d07 67 PRINTS PR00050 Cold shock protein signature 25 34 2.1E-18 T 01-11-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MLA2C4_21595 22331a7f062a4a68cfb160f34e646d3f 186 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 19 171 4.9E-21 T 01-11-2018 IPR018639 Domain of unknown function DUF2062 MLA2C4_05410 dc2599d6f19c5a79e7234715902a4d38 61 Pfam PF14120 YhzD-like protein 1 61 3.2E-26 T 01-11-2018 IPR025544 YhzD-like protein MLA2C4_08235 b27dcade7413b7e371cc8ee9b5ecab62 440 Pfam PF00860 Permease family 7 385 1.4E-114 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_08235 b27dcade7413b7e371cc8ee9b5ecab62 440 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 415 2.4E-138 T 01-11-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MLA2C4_08235 b27dcade7413b7e371cc8ee9b5ecab62 440 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 7.0E-168 T 01-11-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 MLA2C4_08235 b27dcade7413b7e371cc8ee9b5ecab62 440 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 01-11-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MLA2C4_17380 560258a917e6b34ce3cb0031d18c8f40 218 Pfam PF11139 Sap, sulfolipid-1-addressing protein 11 215 4.7E-27 T 01-11-2018 IPR021315 Glycolipid exporter Gap/Sap MLA2C4_12760 8434396bf6ec821eedf5b9108d827d53 382 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 380 36.502 T 01-11-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MLA2C4_12760 8434396bf6ec821eedf5b9108d827d53 382 SUPERFAMILY SSF53067 1 326 8.81E-18 T 01-11-2018 MLA2C4_12760 8434396bf6ec821eedf5b9108d827d53 382 Gene3D G3DSA:3.30.420.40 8 375 1.1E-127 T 01-11-2018 MLA2C4_12760 8434396bf6ec821eedf5b9108d827d53 382 Gene3D G3DSA:3.30.420.40 149 340 1.1E-127 T 01-11-2018 MLA2C4_12760 8434396bf6ec821eedf5b9108d827d53 382 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 378 7.3E-98 T 01-11-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MLA2C4_14950 6ae43cad6db18c7c784f415082d6eb10 167 Pfam PF00583 Acetyltransferase (GNAT) family 47 139 1.8E-15 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14950 6ae43cad6db18c7c784f415082d6eb10 167 Gene3D G3DSA:3.40.630.30 3 167 4.7E-44 T 01-11-2018 MLA2C4_14950 6ae43cad6db18c7c784f415082d6eb10 167 SUPERFAMILY SSF55729 13 167 1.18E-27 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_18045 5fdd00d2e86b12e644e071208a62b218 365 Pfam PF12730 ABC-2 family transporter protein 176 306 3.2E-6 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 SUPERFAMILY SSF118215 31 443 1.16E-94 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 Pfam PF00375 Sodium:dicarboxylate symporter family 32 443 2.7E-100 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 Gene3D G3DSA:1.10.3860.10 20 461 5.5E-107 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 1.1E-17 T 01-11-2018 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 1.1E-17 T 01-11-2018 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 1.1E-17 T 01-11-2018 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 1.1E-17 T 01-11-2018 MLA2C4_22205 18c331798af65bd852071f2f397f933d 464 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 1.1E-17 T 01-11-2018 MLA2C4_27855 957b70282a504dae75a269009aefdd96 338 Pfam PF01032 FecCD transport family 20 336 8.9E-96 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_27855 957b70282a504dae75a269009aefdd96 338 Gene3D G3DSA:1.10.3470.10 7 338 3.7E-101 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_27855 957b70282a504dae75a269009aefdd96 338 SUPERFAMILY SSF81345 7 336 9.02E-87 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 Gene3D G3DSA:3.40.50.300 342 582 2.8E-90 T 01-11-2018 MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 Pfam PF00664 ABC transporter transmembrane region 31 298 1.1E-47 T 01-11-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 SUPERFAMILY SSF52540 333 578 1.25E-89 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 Pfam PF00005 ABC transporter 358 508 4.5E-36 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 Gene3D G3DSA:1.20.1560.10 1 330 2.0E-82 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 SMART SM00382 367 554 1.5E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 SUPERFAMILY SSF90123 18 325 1.7E-74 T 01-11-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MLA2C4_09930 4a880b1641180b2b6d3abfe1ab9af021 586 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_02250 f6d67261e61ea549008097375452848d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_02250 f6d67261e61ea549008097375452848d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_02250 f6d67261e61ea549008097375452848d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_02250 f6d67261e61ea549008097375452848d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_02250 f6d67261e61ea549008097375452848d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_02250 f6d67261e61ea549008097375452848d 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_02250 f6d67261e61ea549008097375452848d 238 SUPERFAMILY SSF51735 5 237 9.85E-43 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_02250 f6d67261e61ea549008097375452848d 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 43 236 7.0E-39 T 01-11-2018 MLA2C4_02250 f6d67261e61ea549008097375452848d 238 Gene3D G3DSA:3.40.50.720 9 238 1.5E-39 T 01-11-2018 MLA2C4_02250 f6d67261e61ea549008097375452848d 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_20845 0141d84147c5bbd924a4d01f04298182 162 Pfam PF13158 Protein of unknown function (DUF3993) 9 123 3.1E-43 T 01-11-2018 IPR025056 Protein of unknown function DUF3993 MLA2C4_03740 5abc6eca53bc4272d90e1dda97a62fd3 388 Gene3D G3DSA:3.30.300.210 229 382 2.7E-33 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_03740 5abc6eca53bc4272d90e1dda97a62fd3 388 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 212 380 2.9E-33 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_03740 5abc6eca53bc4272d90e1dda97a62fd3 388 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 381 5.7E-102 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 7.8E-118 T 01-11-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.019 T 01-11-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 Pfam PF01070 FMN-dependent dehydrogenase 167 322 1.6E-17 T 01-11-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 PIRSF PIRSF003314 2 340 1.5E-121 T 01-11-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 SMART SM01240 21 336 0.0082 T 01-11-2018 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 SUPERFAMILY SSF51395 22 348 3.14E-83 T 01-11-2018 MLA2C4_07890 7993f8d0f5f425c8492ed80e802469ba 349 Gene3D G3DSA:3.20.20.70 3 349 1.2E-125 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_15910 58172be8238ca1db40a23b6a40183629 168 Pfam PF13042 Protein of unknown function (DUF3902) 2 162 3.3E-81 T 01-11-2018 IPR025001 Protein of unknown function DUF3902 MLA2C4_15645 375c998bc32ab13a923148c0a8f3e646 348 PIRSF PIRSF012608 1 348 2.0E-139 T 01-11-2018 IPR011200 Uncharacterised conserved protein UCP012608 MLA2C4_15645 375c998bc32ab13a923148c0a8f3e646 348 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 9 340 1.2E-114 T 01-11-2018 IPR011200 Uncharacterised conserved protein UCP012608 MLA2C4_24445 4bf4c36e606a625623db4509c94bdf53 92 Pfam PF14165 YtzH-like protein 3 88 2.8E-38 T 01-11-2018 IPR025547 YtzH-like protein MLA2C4_25520 5066f64a3be2c3952e791789b32fc1a3 165 SUPERFAMILY SSF54909 65 146 1.88E-16 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_25520 5066f64a3be2c3952e791789b32fc1a3 165 Gene3D G3DSA:3.30.70.920 55 152 3.9E-19 T 01-11-2018 MLA2C4_25520 5066f64a3be2c3952e791789b32fc1a3 165 SUPERFAMILY SSF46785 4 59 3.21E-7 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_25520 5066f64a3be2c3952e791789b32fc1a3 165 Gene3D G3DSA:1.10.10.10 2 52 7.0E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25520 5066f64a3be2c3952e791789b32fc1a3 165 Pfam PF01037 Lrp/AsnC ligand binding domain 72 143 1.6E-12 T 01-11-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MLA2C4_25520 5066f64a3be2c3952e791789b32fc1a3 165 SMART SM00344 4 115 0.0081 T 01-11-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 SUPERFAMILY SSF89082 157 242 1.96E-29 T 01-11-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 SUPERFAMILY SSF46955 3 114 2.2E-30 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 Pfam PF13411 MerR HTH family regulatory protein 3 69 9.6E-18 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 Gene3D G3DSA:1.10.490.50 155 243 2.2E-22 T 01-11-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 Gene3D G3DSA:1.10.1660.10 1 139 3.1E-53 T 01-11-2018 MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 Pfam PF07739 TipAS antibiotic-recognition domain 130 238 1.7E-32 T 01-11-2018 IPR012925 TipAS antibiotic-recognition domain MLA2C4_25850 0cac6bb12b69fcc1709fea4af93a92bb 243 SMART SM00422 3 72 8.9E-26 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_24385 1abfa57c941c4c2bb63ff83512f018d0 372 PIRSF PIRSF000484 15 364 1.2E-65 T 01-11-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MLA2C4_24385 1abfa57c941c4c2bb63ff83512f018d0 372 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 47 118 7.4E-8 T 01-11-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MLA2C4_24385 1abfa57c941c4c2bb63ff83512f018d0 372 Gene3D G3DSA:3.90.1170.20 12 118 1.1E-16 T 01-11-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 MLA2C4_24385 1abfa57c941c4c2bb63ff83512f018d0 372 SUPERFAMILY SSF51690 128 355 7.21E-48 T 01-11-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MLA2C4_24385 1abfa57c941c4c2bb63ff83512f018d0 372 Gene3D G3DSA:3.20.20.70 120 333 1.3E-64 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_24385 1abfa57c941c4c2bb63ff83512f018d0 372 SUPERFAMILY SSF54675 18 128 8.44E-22 T 01-11-2018 MLA2C4_22880 f86d8aab21bf86d4756dcced5d1f6597 137 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 3.0E-52 T 01-11-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MLA2C4_22880 f86d8aab21bf86d4756dcced5d1f6597 137 Pfam PF03652 Holliday junction resolvase 1 136 1.2E-47 T 01-11-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MLA2C4_22880 f86d8aab21bf86d4756dcced5d1f6597 137 SUPERFAMILY SSF53098 1 136 4.55E-47 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_22880 f86d8aab21bf86d4756dcced5d1f6597 137 SMART SM00732 1 103 1.7E-41 T 01-11-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MLA2C4_22880 f86d8aab21bf86d4756dcced5d1f6597 137 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 137 25.841 T 01-11-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MLA2C4_22880 f86d8aab21bf86d4756dcced5d1f6597 137 Gene3D G3DSA:3.30.420.140 1 137 1.8E-53 T 01-11-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MLA2C4_23580 cbc95e3de26bbbc1bf412aa997fb2702 307 Pfam PF00005 ABC transporter 21 161 2.1E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_23580 cbc95e3de26bbbc1bf412aa997fb2702 307 Gene3D G3DSA:3.40.50.300 1 238 3.3E-57 T 01-11-2018 MLA2C4_23580 cbc95e3de26bbbc1bf412aa997fb2702 307 SUPERFAMILY SSF52540 3 222 4.49E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23580 cbc95e3de26bbbc1bf412aa997fb2702 307 SMART SM00382 29 210 6.2E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_23580 cbc95e3de26bbbc1bf412aa997fb2702 307 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_08610 b26bfe47b0fb1b8669ced7e656889b6e 524 Pfam PF01514 Secretory protein of YscJ/FliF family 20 211 8.3E-42 T 01-11-2018 IPR006182 Secretory protein YscJ/FliF MLA2C4_08610 b26bfe47b0fb1b8669ced7e656889b6e 524 PRINTS PR01009 Flagellar M-ring protein signature 187 205 1.4E-7 T 01-11-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MLA2C4_08610 b26bfe47b0fb1b8669ced7e656889b6e 524 PRINTS PR01009 Flagellar M-ring protein signature 337 361 1.4E-7 T 01-11-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MLA2C4_08610 b26bfe47b0fb1b8669ced7e656889b6e 524 PRINTS PR01009 Flagellar M-ring protein signature 143 157 1.4E-7 T 01-11-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MLA2C4_08610 b26bfe47b0fb1b8669ced7e656889b6e 524 Pfam PF08345 Flagellar M-ring protein C-terminal 247 407 1.9E-19 T 01-11-2018 IPR013556 Flagellar M-ring C-terminal MLA2C4_08610 b26bfe47b0fb1b8669ced7e656889b6e 524 Gene3D G3DSA:3.30.300.30 108 217 5.0E-6 T 01-11-2018 MLA2C4_28220 660347bfa4fe520b63466c6bf9028107 196 Pfam PF02293 AmiS/UreI family transporter 1 164 2.4E-49 T 01-11-2018 IPR003211 AmiS/UreI transporter GO:0016020 MLA2C4_28220 660347bfa4fe520b63466c6bf9028107 196 Gene3D G3DSA:1.25.40.600 1 167 4.3E-39 T 01-11-2018 IPR038523 AmiS/UreI transporter superfamily MLA2C4_26860 e34710bf19548ef2d721f0c27bc6ce85 234 Gene3D G3DSA:3.40.50.2020 79 234 1.1E-17 T 01-11-2018 MLA2C4_26860 e34710bf19548ef2d721f0c27bc6ce85 234 SUPERFAMILY SSF53271 76 232 2.27E-24 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_26860 e34710bf19548ef2d721f0c27bc6ce85 234 Pfam PF00156 Phosphoribosyl transferase domain 144 232 7.3E-8 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_26615 22af029d40601c9540aabf5aa761563b 161 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 35 141 1.7E-6 T 01-11-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like MLA2C4_18065 8fb9ab9459e35170245aaf3b1264c114 344 SUPERFAMILY SSF81345 13 339 6.02E-83 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_18065 8fb9ab9459e35170245aaf3b1264c114 344 Pfam PF01032 FecCD transport family 30 339 7.2E-90 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_18065 8fb9ab9459e35170245aaf3b1264c114 344 Gene3D G3DSA:1.10.3470.10 16 342 5.4E-91 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_27075 4c36f6713dcdd792bdb6646044936596 403 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 401 5.8E-136 T 01-11-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 MLA2C4_27075 4c36f6713dcdd792bdb6646044936596 403 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 196 401 8.5E-70 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_27075 4c36f6713dcdd792bdb6646044936596 403 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 3.9E-22 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_09755 2687dc99c530efd33c42bbd3e0a54f50 139 SUPERFAMILY SSF55729 12 129 2.03E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_09755 2687dc99c530efd33c42bbd3e0a54f50 139 Pfam PF13673 Acetyltransferase (GNAT) domain 30 128 4.5E-16 T 01-11-2018 IPR000182 GNAT domain MLA2C4_09755 2687dc99c530efd33c42bbd3e0a54f50 139 Gene3D G3DSA:3.40.630.30 4 135 3.8E-37 T 01-11-2018 MLA2C4_07000 96e88e831dd2079990064cd52c0f7a99 397 Pfam PF01266 FAD dependent oxidoreductase 29 380 4.3E-43 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_07000 96e88e831dd2079990064cd52c0f7a99 397 Gene3D G3DSA:3.30.9.10 122 343 8.9E-58 T 01-11-2018 MLA2C4_07000 96e88e831dd2079990064cd52c0f7a99 397 Gene3D G3DSA:3.50.50.60 29 383 8.9E-58 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_07000 96e88e831dd2079990064cd52c0f7a99 397 SUPERFAMILY SSF51905 28 387 2.43E-32 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_27030 358d6903fcece7413698148979a8cfee 586 Pfam PF13667 ThiC-associated domain 16 88 1.7E-27 T 01-11-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MLA2C4_27030 358d6903fcece7413698148979a8cfee 586 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 128 552 3.3E-223 T 01-11-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MLA2C4_27030 358d6903fcece7413698148979a8cfee 586 Pfam PF01964 Radical SAM ThiC family 129 549 4.5E-205 T 01-11-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MLA2C4_27030 358d6903fcece7413698148979a8cfee 586 Gene3D G3DSA:3.20.20.540 173 485 2.4E-156 T 01-11-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MLA2C4_27030 358d6903fcece7413698148979a8cfee 586 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 128 554 99.506 T 01-11-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MLA2C4_04060 7e7dd54a0ea13555a2cecdd789c78c3b 253 SUPERFAMILY SSF141523 23 142 6.54E-35 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_04060 7e7dd54a0ea13555a2cecdd789c78c3b 253 Pfam PF03734 L,D-transpeptidase catalytic domain 24 142 1.3E-24 T 01-11-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MLA2C4_04060 7e7dd54a0ea13555a2cecdd789c78c3b 253 Gene3D G3DSA:2.40.440.10 12 174 9.9E-43 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 SUPERFAMILY SSF56601 321 693 7.44E-66 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 SUPERFAMILY SSF56519 56 320 2.88E-37 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 Gene3D G3DSA:3.40.710.10 320 681 1.6E-220 T 01-11-2018 MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 Gene3D G3DSA:1.10.10.1230 87 196 1.6E-220 T 01-11-2018 MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 Gene3D G3DSA:3.90.1310.30 62 575 1.6E-220 T 01-11-2018 MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 686 6.4E-65 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_13350 72a9c688de8408e1b74b061c0b0ecaa7 710 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 305 2.8E-38 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_09695 23ff01b1377366d43596eb821ce21cfd 230 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 24 230 27.369 T 01-11-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MLA2C4_09695 23ff01b1377366d43596eb821ce21cfd 230 SUPERFAMILY SSF52218 23 230 6.54E-46 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_09695 23ff01b1377366d43596eb821ce21cfd 230 Gene3D G3DSA:3.40.50.360 20 230 2.4E-54 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_09695 23ff01b1377366d43596eb821ce21cfd 230 Pfam PF02525 Flavodoxin-like fold 25 225 5.4E-41 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_01005 50c378c54d97fb55b69447f35d1aeb7a 433 Gene3D G3DSA:2.60.40.4170 69 245 4.3E-10 T 01-11-2018 MLA2C4_01005 50c378c54d97fb55b69447f35d1aeb7a 433 Pfam PF16781 Domain of unknown function (DUF5068) 71 234 7.1E-15 T 01-11-2018 IPR031888 Protein of unknown function DUF5068 MLA2C4_27940 e03b8d81c52e912bf08da9268291533f 122 Pfam PF04241 Protein of unknown function (DUF423) 18 104 2.3E-32 T 01-11-2018 IPR006696 Protein of unknown function DUF423 MLA2C4_16990 69d6a690f0055a662a7b0c461f97bfab 264 SUPERFAMILY SSF46955 2 111 3.08E-20 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_16990 69d6a690f0055a662a7b0c461f97bfab 264 Pfam PF13411 MerR HTH family regulatory protein 2 70 8.3E-14 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_16990 69d6a690f0055a662a7b0c461f97bfab 264 SMART SM00422 2 71 3.9E-8 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_16990 69d6a690f0055a662a7b0c461f97bfab 264 Gene3D G3DSA:1.10.1660.10 1 124 1.9E-19 T 01-11-2018 MLA2C4_21705 7286896dd906917ad7518c4bd1edc8f5 186 SUPERFAMILY SSF141523 26 151 1.16E-33 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_21705 7286896dd906917ad7518c4bd1edc8f5 186 Gene3D G3DSA:2.40.440.10 14 178 1.3E-44 T 01-11-2018 IPR038063 L,D-transpeptidase catalytic domain-like MLA2C4_21705 7286896dd906917ad7518c4bd1edc8f5 186 Pfam PF03734 L,D-transpeptidase catalytic domain 28 151 2.1E-23 T 01-11-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MLA2C4_06850 44f74577cb93ca0445229cda54bda622 266 SUPERFAMILY SSF161098 4 253 1.27E-60 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06850 44f74577cb93ca0445229cda54bda622 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 249 4.2E-18 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_06850 44f74577cb93ca0445229cda54bda622 266 Gene3D G3DSA:1.10.3720.10 1 255 3.2E-56 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_25550 99b4c21f157236899308b93d08a2a251 127 Pfam PF08810 Kinase associated protein B 15 126 4.2E-49 T 01-11-2018 IPR014916 Kinase associated protein B MLA2C4_25550 99b4c21f157236899308b93d08a2a251 127 SMART SM01298 15 127 1.3E-72 T 01-11-2018 IPR014916 Kinase associated protein B MLA2C4_25550 99b4c21f157236899308b93d08a2a251 127 SUPERFAMILY SSF141251 4 126 4.84E-52 T 01-11-2018 IPR038080 Kinase associated protein B superfamily MLA2C4_25550 99b4c21f157236899308b93d08a2a251 127 Gene3D G3DSA:2.30.30.430 1 127 1.7E-54 T 01-11-2018 IPR038080 Kinase associated protein B superfamily MLA2C4_08970 f7c25173161bb4631cae37966c5fd272 467 Pfam PF03553 Na+/H+ antiporter family 159 451 7.8E-67 T 01-11-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MLA2C4_08970 f7c25173161bb4631cae37966c5fd272 467 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 457 9.3E-200 T 01-11-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 MLA2C4_02400 55c0b8fc8dc78cc713eea9d7e048e062 292 Gene3D G3DSA:3.30.420.40 108 292 5.6E-55 T 01-11-2018 MLA2C4_02400 55c0b8fc8dc78cc713eea9d7e048e062 292 Pfam PF00480 ROK family 4 285 1.2E-49 T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_02400 55c0b8fc8dc78cc713eea9d7e048e062 292 SUPERFAMILY SSF53067 3 291 1.62E-61 T 01-11-2018 MLA2C4_02400 55c0b8fc8dc78cc713eea9d7e048e062 292 Gene3D G3DSA:3.30.420.40 1 107 2.1E-22 T 01-11-2018 MLA2C4_28090 1d32aa54e8008a67f5816b3b1319b38d 468 Pfam PF13425 O-antigen ligase like membrane protein 9 467 3.7E-143 T 01-11-2018 MLA2C4_02745 82e5761309d2c3aa5c769065eed4d217 362 Pfam PF06081 Aromatic acid exporter family member 1 1 142 1.1E-45 T 01-11-2018 IPR010343 Aromatic acid exporter family member 1 MLA2C4_16715 804933e0d958f4b7628012f665271eea 303 PIRSF PIRSF005355 1 302 5.2E-84 T 01-11-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 MLA2C4_16715 804933e0d958f4b7628012f665271eea 303 Pfam PF01040 UbiA prenyltransferase family 27 254 4.2E-35 T 01-11-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MLA2C4_16715 804933e0d958f4b7628012f665271eea 303 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 294 4.6E-35 T 01-11-2018 MLA2C4_16715 804933e0d958f4b7628012f665271eea 303 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 297 18.676 T 01-11-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MLA2C4_14580 77afb74c1e27fbfe2aa080198e82deea 198 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 25 152 2.8E-17 T 01-11-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like MLA2C4_14580 77afb74c1e27fbfe2aa080198e82deea 198 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 4 154 1.0E-50 T 01-11-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 442 2.5E-157 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 97 112 - T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 PRINTS PR00175 Sodium/alanine symporter signature 215 234 2.4E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 PRINTS PR00175 Sodium/alanine symporter signature 187 205 2.4E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 PRINTS PR00175 Sodium/alanine symporter signature 411 431 2.4E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 PRINTS PR00175 Sodium/alanine symporter signature 97 119 2.4E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 PRINTS PR00175 Sodium/alanine symporter signature 306 324 2.4E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 PRINTS PR00175 Sodium/alanine symporter signature 351 373 2.4E-60 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26335 f2a690d222792e80c516349e516ac77e 479 Pfam PF01235 Sodium:alanine symporter family 59 454 5.6E-163 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.1E-35 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.1E-35 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.1E-35 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.1E-35 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00097 Anthranilate synthase component II signature 165 178 4.1E-35 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.1E-35 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 Gene3D G3DSA:3.40.50.880 1 187 2.3E-62 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 3.0E-70 T 01-11-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.8E-14 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.8E-14 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.8E-14 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 Pfam PF00117 Glutamine amidotransferase class-I 3 186 4.6E-53 T 01-11-2018 IPR017926 Glutamine amidotransferase MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.2E-8 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.2E-8 T 01-11-2018 MLA2C4_06495 ff20f042212b910c126ca946f80f500e 195 SUPERFAMILY SSF52317 1 187 2.1E-53 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_08000 794ab89cd1d716e79a493068f623ffec 151 Pfam PF10673 Protein of unknown function (DUF2487) 9 149 8.3E-53 T 01-11-2018 IPR019615 Protein of unknown function DUF2487 MLA2C4_00570 9e946bc69e5ec7f0da333674388273f5 135 Gene3D G3DSA:1.10.1520.10 1 135 4.0E-52 T 01-11-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MLA2C4_00570 9e946bc69e5ec7f0da333674388273f5 135 PIRSF PIRSF005520 1 132 7.5E-54 T 01-11-2018 IPR008226 Mini-ribonuclease 3 family MLA2C4_00570 9e946bc69e5ec7f0da333674388273f5 135 Pfam PF00636 Ribonuclease III domain 11 108 3.0E-15 T 01-11-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MLA2C4_00570 9e946bc69e5ec7f0da333674388273f5 135 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 127 30.468 T 01-11-2018 IPR008226 Mini-ribonuclease 3 family MLA2C4_00570 9e946bc69e5ec7f0da333674388273f5 135 SMART SM00535 1 128 0.0014 T 01-11-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MLA2C4_00570 9e946bc69e5ec7f0da333674388273f5 135 SUPERFAMILY SSF69065 3 126 2.79E-44 T 01-11-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MLA2C4_09000 305646c43c15f02270626a8f2c9b2037 469 Pfam PF01554 MatE 34 194 5.1E-37 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_09000 305646c43c15f02270626a8f2c9b2037 469 Pfam PF01554 MatE 263 423 2.8E-32 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_09000 305646c43c15f02270626a8f2c9b2037 469 PIRSF PIRSF006603 8 468 2.4E-133 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_09000 305646c43c15f02270626a8f2c9b2037 469 TIGRFAM TIGR00797 matE: MATE efflux family protein 34 437 1.3E-97 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_08940 d596c4e722a44daf102cbc7c9743968c 357 SUPERFAMILY SSF110296 28 334 5.36E-45 T 01-11-2018 MLA2C4_08940 d596c4e722a44daf102cbc7c9743968c 357 Gene3D G3DSA:2.130.10.10 75 341 1.2E-47 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MLA2C4_09730 fbbe00cdb1b5f4c596ff5980c961a322 301 SUPERFAMILY SSF103481 186 289 4.05E-9 T 01-11-2018 MLA2C4_09730 fbbe00cdb1b5f4c596ff5980c961a322 301 Pfam PF00892 EamA-like transporter family 11 140 4.5E-25 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_09730 fbbe00cdb1b5f4c596ff5980c961a322 301 Pfam PF00892 EamA-like transporter family 151 286 6.1E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_09730 fbbe00cdb1b5f4c596ff5980c961a322 301 SUPERFAMILY SSF103481 43 143 1.11E-14 T 01-11-2018 MLA2C4_28335 6d0065b809684e380d46fce1cad3d7c2 280 Pfam PF09648 YycH protein 33 252 4.9E-59 T 01-11-2018 IPR018604 Regulatory protein YycH-like GO:0016021 MLA2C4_28335 6d0065b809684e380d46fce1cad3d7c2 280 Gene3D G3DSA:3.30.310.160 70 179 1.1E-60 T 01-11-2018 MLA2C4_28335 6d0065b809684e380d46fce1cad3d7c2 280 Gene3D G3DSA:3.10.450.660 47 256 1.1E-60 T 01-11-2018 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 Gene3D G3DSA:3.50.50.60 7 304 6.0E-120 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 293 9.2E-30 T 01-11-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 9.7E-19 T 01-11-2018 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 9.7E-19 T 01-11-2018 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 9.7E-19 T 01-11-2018 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 9.7E-19 T 01-11-2018 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 Gene3D G3DSA:3.50.50.60 128 246 6.0E-120 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 SUPERFAMILY SSF51905 8 314 1.64E-40 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 Hamap MF_01685 Ferredoxin--NADP reductase. 7 328 44.647 T 01-11-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 1.8E-23 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.8E-23 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 1.8E-23 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 1.8E-23 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_25640 893ebedbbf6e97f60eed552514c8a96e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 1.8E-23 T 01-11-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MLA2C4_08865 ea10c0a979df08d6ee5d6a69be7442f9 140 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 131 1.5E-60 T 01-11-2018 IPR019723 Uncharacterised protein, YfmQ MLA2C4_13935 88d5f648114ccf044a803c7fa68aea21 74 Pfam PF10779 Haemolysin XhlA 6 68 5.7E-9 T 01-11-2018 IPR019715 Haemolysin XhlA MLA2C4_11785 83b4c24ce8008bf9641259cf00337dba 331 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 164 277 1.1E-10 T 01-11-2018 IPR006528 Phage head morphogenesis domain MLA2C4_11785 83b4c24ce8008bf9641259cf00337dba 331 Pfam PF04233 Phage Mu protein F like protein 160 272 9.0E-9 T 01-11-2018 IPR006528 Phage head morphogenesis domain MLA2C4_28065 3bbeca99da439797b444596453c43453 691 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 5.9E-36 T 01-11-2018 IPR025299 CstA, C-terminal domain MLA2C4_28065 3bbeca99da439797b444596453c43453 691 Pfam PF02554 Carbon starvation protein CstA 32 409 3.7E-172 T 01-11-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MLA2C4_25135 c03d3b627042fd5acc617043db9d8710 89 Pfam PF08863 YolD-like protein 24 88 4.4E-12 T 01-11-2018 IPR014962 YolD-like protein MLA2C4_11520 f600c9f6cbcfc4ef7ba9d672f82dcaed 59 Pfam PF14162 YozD-like protein 1 56 6.5E-30 T 01-11-2018 IPR025545 YozD-like protein MLA2C4_11520 f600c9f6cbcfc4ef7ba9d672f82dcaed 59 ProDom PD052277 YOZD 1 56 1.0E-23 T 01-11-2018 MLA2C4_10560 2e6c6ca22304b96b0afb59672e2927b2 153 Pfam PF05163 DinB family 18 140 1.1E-5 T 01-11-2018 IPR007837 DNA damage-inducible protein DinB MLA2C4_10560 2e6c6ca22304b96b0afb59672e2927b2 153 Gene3D G3DSA:1.20.120.450 1 145 7.7E-40 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_10560 2e6c6ca22304b96b0afb59672e2927b2 153 SUPERFAMILY SSF109854 1 140 2.01E-31 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 SUPERFAMILY SSF54506 3 284 9.65E-52 T 01-11-2018 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 Gene3D G3DSA:3.10.310.10 126 274 1.7E-120 T 01-11-2018 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 37.82 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 5.6E-96 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 01-11-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 Pfam PF01678 Diaminopimelate epimerase 6 130 7.7E-32 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 Pfam PF01678 Diaminopimelate epimerase 161 276 3.4E-35 T 01-11-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MLA2C4_25705 a0c1e44c73c4ea8dbe66ab61bba1c930 288 Gene3D G3DSA:3.10.310.10 6 280 1.7E-120 T 01-11-2018 MLA2C4_15920 79d6c4e8d4c42ac22896b8ee1c4b2b0d 369 Pfam PF01882 Protein of unknown function DUF58 211 289 4.8E-12 T 01-11-2018 IPR002881 Domain of unknown function DUF58 MLA2C4_25060 815d4eb5b8b5ac1265c7571d87004057 169 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 134 166 2.5E-4 T 01-11-2018 MLA2C4_28265 37c935c862f6657d4659dcd4056cc820 215 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 7 214 1.9E-60 T 01-11-2018 IPR005744 Hly-III GO:0016021|GO:0019835 MLA2C4_28265 37c935c862f6657d4659dcd4056cc820 215 Pfam PF03006 Haemolysin-III related 4 207 9.9E-47 T 01-11-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 SUPERFAMILY SSF53187 3 406 1.63E-82 T 01-11-2018 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 Gene3D G3DSA:3.40.630.10 5 402 4.0E-186 T 01-11-2018 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 4.5E-201 T 01-11-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 01-11-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 Gene3D G3DSA:3.30.70.360 211 321 4.0E-186 T 01-11-2018 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 01-11-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 PIRSF PIRSF037215 1 410 1.0E-193 T 01-11-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 58.192 T 01-11-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 SUPERFAMILY SSF55031 211 322 4.81E-39 T 01-11-2018 IPR036264 Bacterial exopeptidase dimerisation domain MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 Pfam PF07687 Peptidase dimerisation domain 209 308 3.4E-11 T 01-11-2018 IPR011650 Peptidase M20, dimerisation domain MLA2C4_19550 f552a46817f06992a625a5f36cdefa30 410 Pfam PF01546 Peptidase family M20/M25/M40 141 404 1.1E-11 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_08355 f8db4a84683bd6a3701ad345db8e0cbb 219 Pfam PF13456 Reverse transcriptase-like 78 205 8.9E-15 T 01-11-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MLA2C4_08355 f8db4a84683bd6a3701ad345db8e0cbb 219 Gene3D G3DSA:3.30.420.10 73 217 2.4E-27 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_08355 f8db4a84683bd6a3701ad345db8e0cbb 219 SUPERFAMILY SSF53098 74 208 2.28E-18 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 Pfam PF00005 ABC transporter 351 478 1.2E-20 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 Pfam PF12848 ABC transporter 230 324 4.8E-24 T 01-11-2018 IPR032781 ABC-transporter extension domain MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 Pfam PF00005 ABC transporter 20 191 1.9E-25 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 Gene3D G3DSA:3.40.50.300 2 285 8.8E-73 T 01-11-2018 MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 SUPERFAMILY SSF52540 323 534 4.11E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 SUPERFAMILY SSF52540 6 244 6.9E-52 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 Gene3D G3DSA:3.40.50.300 298 559 8.7E-59 T 01-11-2018 MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 SMART SM00382 28 243 3.6E-9 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_01255 15afeb68d4bc91fd1d3b26f9e6672ef6 626 SMART SM00382 359 529 6.2E-12 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_20565 24b5e8dc1bdfb4c973f0be5bbbb5083c 145 Pfam PF14071 Putative coat protein 13 145 3.4E-42 T 01-11-2018 IPR025953 Putative coat protein YlbD MLA2C4_11465 8053b990533fe159b468878ecf301aa1 436 SUPERFAMILY SSF53383 9 427 5.63E-116 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_11465 8053b990533fe159b468878ecf301aa1 436 PIRSF PIRSF000521 16 427 9.4E-43 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_11465 8053b990533fe159b468878ecf301aa1 436 Gene3D G3DSA:3.90.1150.10 15 424 5.0E-139 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_11465 8053b990533fe159b468878ecf301aa1 436 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_11465 8053b990533fe159b468878ecf301aa1 436 Gene3D G3DSA:3.40.640.10 49 324 5.0E-139 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_11465 8053b990533fe159b468878ecf301aa1 436 Pfam PF00202 Aminotransferase class-III 16 422 2.9E-103 T 01-11-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MLA2C4_24075 a6b4ff406150c56f16acf068c55790fa 220 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 202 2.1E-44 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_21365 487b917268e207eaf895131c2f4ace6d 223 Gene3D G3DSA:3.30.110.170 25 220 6.1E-50 T 01-11-2018 MLA2C4_21365 487b917268e207eaf895131c2f4ace6d 223 Pfam PF04402 Protein of unknown function (DUF541) 23 220 3.2E-38 T 01-11-2018 IPR007497 Protein of unknown function DUF541 MLA2C4_21365 487b917268e207eaf895131c2f4ace6d 223 Gene3D G3DSA:3.30.70.2970 35 141 6.1E-50 T 01-11-2018 MLA2C4_26365 bc9fbf08e203c27c1d2416c3dbda070d 404 Gene3D G3DSA:1.20.1250.20 9 396 8.8E-48 T 01-11-2018 MLA2C4_26365 bc9fbf08e203c27c1d2416c3dbda070d 404 SUPERFAMILY SSF103473 12 396 1.44E-59 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_26365 bc9fbf08e203c27c1d2416c3dbda070d 404 Pfam PF07690 Major Facilitator Superfamily 24 330 6.8E-41 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_10185 f1b0098b07cf80a3062fc5048be3fba2 494 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 19 228 1.5E-34 T 01-11-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MLA2C4_10185 f1b0098b07cf80a3062fc5048be3fba2 494 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 257 274 - T 01-11-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MLA2C4_10185 f1b0098b07cf80a3062fc5048be3fba2 494 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 6 493 2.6E-205 T 01-11-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MLA2C4_10185 f1b0098b07cf80a3062fc5048be3fba2 494 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 494 252.129 T 01-11-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MLA2C4_10185 f1b0098b07cf80a3062fc5048be3fba2 494 PIRSF PIRSF006005 1 494 3.4E-216 T 01-11-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MLA2C4_10185 f1b0098b07cf80a3062fc5048be3fba2 494 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 245 438 1.6E-31 T 01-11-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 Gene3D G3DSA:3.40.630.40 208 404 2.6E-59 T 01-11-2018 MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 SUPERFAMILY SSF53187 210 401 9.73E-53 T 01-11-2018 MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 Pfam PF00395 S-layer homology domain 149 190 3.6E-4 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 Pfam PF00395 S-layer homology domain 32 69 8.4E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 Pfam PF00395 S-layer homology domain 87 129 7.6E-12 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 212 395 3.0E-49 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_18275 4bc4d97ff40d10d389efab0cb8ebce9b 411 SMART SM00646 277 395 4.7E-42 T 01-11-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MLA2C4_08030 1b660a35cf270afde86d12661be803d4 262 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 24 255 3.4E-105 T 01-11-2018 IPR014231 Sporulation protein YpjB MLA2C4_08030 1b660a35cf270afde86d12661be803d4 262 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 25 254 4.2E-86 T 01-11-2018 IPR014231 Sporulation protein YpjB MLA2C4_00110 92ab1ed669201fdabc0b322c205885e0 179 Pfam PF00857 Isochorismatase family 4 163 3.9E-29 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_00110 92ab1ed669201fdabc0b322c205885e0 179 Gene3D G3DSA:3.40.50.850 1 176 1.9E-40 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_00110 92ab1ed669201fdabc0b322c205885e0 179 SUPERFAMILY SSF52499 2 176 2.62E-44 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 439 1.3E-153 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 PRINTS PR00175 Sodium/alanine symporter signature 348 370 2.2E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 PRINTS PR00175 Sodium/alanine symporter signature 303 321 2.2E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 PRINTS PR00175 Sodium/alanine symporter signature 94 116 2.2E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 PRINTS PR00175 Sodium/alanine symporter signature 212 231 2.2E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 PRINTS PR00175 Sodium/alanine symporter signature 184 202 2.2E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 PRINTS PR00175 Sodium/alanine symporter signature 408 428 2.2E-58 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_26285 efdf0c44c64bedbc3ee08786f91c59f6 477 Pfam PF01235 Sodium:alanine symporter family 56 451 9.5E-159 T 01-11-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 Gene3D G3DSA:1.10.287.950 2 313 8.5E-56 T 01-11-2018 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 SMART SM00283 53 313 1.7E-37 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 SUPERFAMILY SSF58104 33 300 5.49E-58 T 01-11-2018 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 74 103 2.4E-19 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 151 178 2.4E-19 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 180 209 2.4E-19 T 01-11-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MLA2C4_03600 b2b91af7280adae0a5b4803bb98e7f03 314 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 127 280 1.7E-40 T 01-11-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MLA2C4_01425 636fbaf1f7e3d53dc62a3a2045f7eb68 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 5.1E-32 T 01-11-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MLA2C4_01425 636fbaf1f7e3d53dc62a3a2045f7eb68 116 SUPERFAMILY SSF50118 2 113 6.54E-41 T 01-11-2018 MLA2C4_01425 636fbaf1f7e3d53dc62a3a2045f7eb68 116 PIRSF PIRSF033490 1 113 3.3E-38 T 01-11-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MLA2C4_01425 636fbaf1f7e3d53dc62a3a2045f7eb68 116 Gene3D G3DSA:2.30.30.110 1 116 6.3E-53 T 01-11-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MLA2C4_10360 fd3a33f32db2a41deb3df699b271847c 205 Pfam PF00293 NUDIX domain 72 177 1.1E-9 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_10360 fd3a33f32db2a41deb3df699b271847c 205 Gene3D G3DSA:3.90.79.10 41 205 3.6E-47 T 01-11-2018 MLA2C4_10360 fd3a33f32db2a41deb3df699b271847c 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 4 58 7.2E-27 T 01-11-2018 MLA2C4_10360 fd3a33f32db2a41deb3df699b271847c 205 SUPERFAMILY SSF55811 47 197 6.36E-28 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_04020 6ea740fa3bb3165e6e9ce4a11d991b2a 284 Pfam PF01734 Patatin-like phospholipase 7 171 2.8E-19 T 01-11-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MLA2C4_04020 6ea740fa3bb3165e6e9ce4a11d991b2a 284 Gene3D G3DSA:3.40.1090.10 3 66 1.2E-11 T 01-11-2018 MLA2C4_04020 6ea740fa3bb3165e6e9ce4a11d991b2a 284 SUPERFAMILY SSF52151 5 275 1.18E-45 T 01-11-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MLA2C4_01625 3c8b13dc4a3279685477133d244ccac7 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 140 2.7E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_01625 3c8b13dc4a3279685477133d244ccac7 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 172 185 2.7E-5 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_01625 3c8b13dc4a3279685477133d244ccac7 319 Pfam PF12146 Serine aminopeptidase, S33 101 186 5.4E-15 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_01625 3c8b13dc4a3279685477133d244ccac7 319 Gene3D G3DSA:3.40.50.1820 70 316 9.0E-44 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_01625 3c8b13dc4a3279685477133d244ccac7 319 SUPERFAMILY SSF53474 72 317 2.41E-43 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_10070 03813d1f7acc3b51a2232d068e8136ca 182 Gene3D G3DSA:3.40.630.30 12 178 1.4E-32 T 01-11-2018 MLA2C4_10070 03813d1f7acc3b51a2232d068e8136ca 182 SUPERFAMILY SSF55729 9 152 1.06E-24 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10070 03813d1f7acc3b51a2232d068e8136ca 182 Pfam PF00583 Acetyltransferase (GNAT) family 48 151 8.7E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_26090 de4fe1d94e7891d070ddbd52d9236274 114 Pfam PF13157 Protein of unknown function (DUF3992) 19 107 1.2E-15 T 01-11-2018 IPR025055 Protein of unknown function DUF3992 MLA2C4_07185 e2c26704a7090c7ff1f4f79220ad0108 126 SUPERFAMILY SSF46785 4 87 1.42E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_07185 e2c26704a7090c7ff1f4f79220ad0108 126 Gene3D G3DSA:1.10.10.10 8 126 2.7E-28 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_07185 e2c26704a7090c7ff1f4f79220ad0108 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 7.5E-17 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_07185 e2c26704a7090c7ff1f4f79220ad0108 126 SMART SM00345 15 74 7.6E-19 T 01-11-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MLA2C4_24985 8e9e99734a7664bc403c90a3c0a51830 344 Pfam PF02698 DUF218 domain 164 313 4.5E-31 T 01-11-2018 IPR003848 Domain of unknown function DUF218 MLA2C4_27860 7488e37fa35ceb75a9791a701df8b0fd 351 SUPERFAMILY SSF81345 22 344 1.23E-83 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_27860 7488e37fa35ceb75a9791a701df8b0fd 351 Pfam PF01032 FecCD transport family 35 344 1.7E-88 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_27860 7488e37fa35ceb75a9791a701df8b0fd 351 Gene3D G3DSA:1.10.3470.10 23 349 1.3E-89 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_17100 60de34585b2a0525c4d6dc0638c59208 125 Gene3D G3DSA:3.10.129.10 1 124 6.9E-19 T 01-11-2018 MLA2C4_17100 60de34585b2a0525c4d6dc0638c59208 125 SUPERFAMILY SSF54637 2 121 7.8E-17 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_03905 b248ac82e34d6e5f8a66b7a4f001e7df 383 Pfam PF13142 Domain of unknown function (DUF3960) 1 89 1.3E-59 T 01-11-2018 IPR025046 Domain of unknown function DUF3960 MLA2C4_03905 b248ac82e34d6e5f8a66b7a4f001e7df 383 Pfam PF13112 Protein of unknown function (DUF3965) 91 381 4.3E-205 T 01-11-2018 IPR025087 Domain of unknown function DUF3965 MLA2C4_15355 d6c8e96d040755e064e7e2f308c2493e 169 Pfam PF13563 2'-5' RNA ligase superfamily 15 151 3.1E-18 T 01-11-2018 MLA2C4_15355 d6c8e96d040755e064e7e2f308c2493e 169 SUPERFAMILY SSF55144 4 167 6.54E-16 T 01-11-2018 IPR009097 Cyclic phosphodiesterase MLA2C4_15355 d6c8e96d040755e064e7e2f308c2493e 169 Gene3D G3DSA:3.90.1140.10 3 168 3.3E-26 T 01-11-2018 MLA2C4_21915 827fd914280a4c6ad13d28079a36305d 390 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 5 383 8.0E-160 T 01-11-2018 IPR014194 Sporulation stage III, protein AE MLA2C4_21915 827fd914280a4c6ad13d28079a36305d 390 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 68 383 1.1E-108 T 01-11-2018 IPR014194 Sporulation stage III, protein AE MLA2C4_26265 d5b168b2d0fbd842c6559c1caa6fd599 144 Pfam PF13058 Protein of unknown function (DUF3920) 17 142 2.4E-69 T 01-11-2018 IPR025033 Protein of unknown function DUF3920 MLA2C4_27825 9cb54e229e77816aaf81babca9f5f366 169 Pfam PF08741 YwhD family 5 166 1.3E-85 T 01-11-2018 IPR014852 Uncharacterised protein YwhD MLA2C4_09605 1f6c9f6f1bd80325e26e9b5dbb65843c 359 Gene3D G3DSA:1.20.1170.10 41 359 5.4E-110 T 01-11-2018 MLA2C4_09605 1f6c9f6f1bd80325e26e9b5dbb65843c 359 SUPERFAMILY SSF58100 34 356 4.71E-98 T 01-11-2018 MLA2C4_09605 1f6c9f6f1bd80325e26e9b5dbb65843c 359 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 47 223 7.7E-58 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_09965 489eebeff7cbe3e5cb40301fbf4804a8 250 Pfam PF12730 ABC-2 family transporter protein 5 181 1.1E-19 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_12310 43eabb17e625ec824e04934dc7de0e4b 252 SUPERFAMILY SSF53474 15 248 5.71E-25 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12310 43eabb17e625ec824e04934dc7de0e4b 252 Pfam PF00561 alpha/beta hydrolase fold 27 141 3.7E-11 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_12310 43eabb17e625ec824e04934dc7de0e4b 252 Gene3D G3DSA:3.40.50.1820 14 250 8.5E-34 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_02060 5551b849559c16933fcf3df7c935d430 346 Gene3D G3DSA:1.10.3470.10 19 344 4.4E-85 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_02060 5551b849559c16933fcf3df7c935d430 346 Pfam PF01032 FecCD transport family 33 340 1.8E-83 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_02060 5551b849559c16933fcf3df7c935d430 346 SUPERFAMILY SSF81345 17 340 2.09E-78 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 Gene3D G3DSA:1.10.520.20 3 106 2.1E-16 T 01-11-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 2.1E-53 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 SUPERFAMILY SSF47928 3 105 1.15E-27 T 01-11-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 21.764 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 01-11-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 2.2E-52 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.7E-28 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 PRINTS PR00125 ATP synthase delta subunit signature 151 169 2.7E-28 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 PRINTS PR00125 ATP synthase delta subunit signature 136 151 2.7E-28 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.7E-28 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27475 ac7866fcc014a0e710de2959a8ef986a 180 PRINTS PR00125 ATP synthase delta subunit signature 6 25 2.7E-28 T 01-11-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_11535 447571dad6592cbce943832d34d6a45c 251 Pfam PF07070 SpoOM protein 2 211 9.3E-78 T 01-11-2018 IPR009776 Sporulation stage 0, protein M MLA2C4_02690 50882a2f4ce95bf39a0c12bc38efe308 50 Pfam PF14139 YpzG-like protein 1 49 5.7E-26 T 01-11-2018 IPR025413 YpzG-like protein MLA2C4_16575 29a86958a1aea31f847e0bcf253f4770 341 SUPERFAMILY SSF53067 5 166 2.59E-7 T 01-11-2018 MLA2C4_16575 29a86958a1aea31f847e0bcf253f4770 341 Gene3D G3DSA:3.30.420.40 6 325 1.7E-27 T 01-11-2018 MLA2C4_16575 29a86958a1aea31f847e0bcf253f4770 341 Gene3D G3DSA:3.30.420.40 171 308 1.7E-27 T 01-11-2018 MLA2C4_27365 77200c4a7f80eeb947736fa7672a5024 339 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 326 3.0E-75 T 01-11-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 MLA2C4_27365 77200c4a7f80eeb947736fa7672a5024 339 Pfam PF08486 Stage II sporulation protein 65 167 3.3E-27 T 01-11-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal MLA2C4_27365 77200c4a7f80eeb947736fa7672a5024 339 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 7 328 1.3E-126 T 01-11-2018 IPR014225 Sporulation stage II, protein D firmicutes MLA2C4_11550 107f4cdf5c6ed8186296d373719fb180 104 SUPERFAMILY SSF52833 2 103 2.34E-26 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_11550 107f4cdf5c6ed8186296d373719fb180 104 Gene3D G3DSA:3.40.30.10 1 103 1.1E-25 T 01-11-2018 MLA2C4_11550 107f4cdf5c6ed8186296d373719fb180 104 Pfam PF00085 Thioredoxin 6 102 1.1E-17 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 MLA2C4_19505 6ee22b67d768b674d3ed7df03dab4bed 273 Pfam PF00005 ABC transporter 20 167 1.6E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_19505 6ee22b67d768b674d3ed7df03dab4bed 273 SMART SM00382 28 217 1.6E-16 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_19505 6ee22b67d768b674d3ed7df03dab4bed 273 SUPERFAMILY SSF52540 3 231 3.62E-60 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_19505 6ee22b67d768b674d3ed7df03dab4bed 273 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_19505 6ee22b67d768b674d3ed7df03dab4bed 273 Gene3D G3DSA:3.40.50.300 1 254 1.9E-68 T 01-11-2018 MLA2C4_00100 f677248a25a15ec866da13d9825a07ec 222 SUPERFAMILY SSF52540 14 215 1.04E-46 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_00100 f677248a25a15ec866da13d9825a07ec 222 Gene3D G3DSA:3.40.50.300 12 217 1.9E-57 T 01-11-2018 MLA2C4_00100 f677248a25a15ec866da13d9825a07ec 222 PIRSF PIRSF000705 2 220 2.5E-64 T 01-11-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 MLA2C4_00100 f677248a25a15ec866da13d9825a07ec 222 Pfam PF01712 Deoxynucleoside kinase 15 214 4.4E-63 T 01-11-2018 IPR031314 Deoxynucleoside kinase domain MLA2C4_21150 1294970a4c536caa221a3e6ed06db199 430 SUPERFAMILY SSF55073 273 427 1.57E-46 T 01-11-2018 IPR029787 Nucleotide cyclase MLA2C4_21150 1294970a4c536caa221a3e6ed06db199 430 SMART SM00267 257 425 2.1E-59 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_21150 1294970a4c536caa221a3e6ed06db199 430 Pfam PF00990 Diguanylate cyclase, GGDEF domain 268 421 1.0E-44 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_21150 1294970a4c536caa221a3e6ed06db199 430 Pfam PF13188 PAS domain 144 179 2.4E-4 T 01-11-2018 IPR000014 PAS domain MLA2C4_21150 1294970a4c536caa221a3e6ed06db199 430 Gene3D G3DSA:3.30.70.270 254 428 2.2E-52 T 01-11-2018 MLA2C4_21150 1294970a4c536caa221a3e6ed06db199 430 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 265 424 6.7E-47 T 01-11-2018 IPR000160 GGDEF domain MLA2C4_03930 6cff3f3d52d87ce95a12433c1056742a 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 243 1.1E-27 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03930 6cff3f3d52d87ce95a12433c1056742a 250 SUPERFAMILY SSF161098 54 231 1.44E-28 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03930 6cff3f3d52d87ce95a12433c1056742a 250 Gene3D G3DSA:1.10.3720.10 49 243 7.2E-25 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_24540 cb8e05da60151550e895555ddbab682f 285 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 284 1.1E-114 T 01-11-2018 MLA2C4_24540 cb8e05da60151550e895555ddbab682f 285 SUPERFAMILY SSF103481 36 137 1.44E-10 T 01-11-2018 MLA2C4_24540 cb8e05da60151550e895555ddbab682f 285 SUPERFAMILY SSF103481 189 271 2.09E-7 T 01-11-2018 MLA2C4_24540 cb8e05da60151550e895555ddbab682f 285 Pfam PF06800 Sugar transport protein 4 282 2.3E-110 T 01-11-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 MLA2C4_08180 4c991132aa5add312c4308fcd5aef95e 143 Pfam PF11122 Inner spore coat protein D 22 109 2.2E-21 T 01-11-2018 IPR020108 Spore coat protein CotD MLA2C4_08180 4c991132aa5add312c4308fcd5aef95e 143 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 22 72 1.0E-20 T 01-11-2018 IPR020108 Spore coat protein CotD MLA2C4_04675 5a7a6881b434df7e2d066c700acead3a 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_04675 5a7a6881b434df7e2d066c700acead3a 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_04675 5a7a6881b434df7e2d066c700acead3a 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.1E-22 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_04675 5a7a6881b434df7e2d066c700acead3a 67 Gene3D G3DSA:1.10.8.910 8 67 7.6E-31 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 SMART SM00244 21 179 3.2E-58 T 01-11-2018 IPR001107 Band 7 domain MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 Pfam PF01145 SPFH domain / Band 7 family 25 195 4.6E-34 T 01-11-2018 IPR001107 Band 7 domain MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 PRINTS PR00721 Stomatin signature 111 128 7.7E-29 T 01-11-2018 IPR001972 Stomatin family GO:0016020 MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 PRINTS PR00721 Stomatin signature 174 195 7.7E-29 T 01-11-2018 IPR001972 Stomatin family GO:0016020 MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 PRINTS PR00721 Stomatin signature 131 154 7.7E-29 T 01-11-2018 IPR001972 Stomatin family GO:0016020 MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 PRINTS PR00721 Stomatin signature 76 97 7.7E-29 T 01-11-2018 IPR001972 Stomatin family GO:0016020 MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 PRINTS PR00721 Stomatin signature 155 173 7.7E-29 T 01-11-2018 IPR001972 Stomatin family GO:0016020 MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 PRINTS PR00721 Stomatin signature 28 50 7.7E-29 T 01-11-2018 IPR001972 Stomatin family GO:0016020 MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 SUPERFAMILY SSF117892 52 186 3.53E-40 T 01-11-2018 IPR036013 Band 7/SPFH domain superfamily MLA2C4_10510 d3dc2e496bd416d165b9ada08c93a9a6 323 Gene3D G3DSA:3.30.479.30 49 181 1.7E-44 T 01-11-2018 MLA2C4_00700 c4d4b3e291d33e5ac0c9919282ebc665 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 01-11-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MLA2C4_00700 c4d4b3e291d33e5ac0c9919282ebc665 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.666 T 01-11-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00700 c4d4b3e291d33e5ac0c9919282ebc665 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.3E-53 T 01-11-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_00700 c4d4b3e291d33e5ac0c9919282ebc665 113 SUPERFAMILY SSF54843 1 112 5.76E-45 T 01-11-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_00700 c4d4b3e291d33e5ac0c9919282ebc665 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 5.2E-38 T 01-11-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MLA2C4_00700 c4d4b3e291d33e5ac0c9919282ebc665 113 Gene3D G3DSA:3.90.470.10 1 113 3.0E-51 T 01-11-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MLA2C4_16080 96e9251670f1dab4a1577edf7b80fcfb 312 SUPERFAMILY SSF56112 21 259 7.85E-35 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_16080 96e9251670f1dab4a1577edf7b80fcfb 312 Pfam PF01636 Phosphotransferase enzyme family 21 249 4.2E-28 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_16080 96e9251670f1dab4a1577edf7b80fcfb 312 Gene3D G3DSA:3.90.1200.10 100 288 1.2E-22 T 01-11-2018 MLA2C4_24155 89b072c239df579315613e29a23bca7f 570 Pfam PF06160 Septation ring formation regulator, EzrA 7 561 1.3E-172 T 01-11-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 MLA2C4_24155 89b072c239df579315613e29a23bca7f 570 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 5 566 21.871 T 01-11-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 SUPERFAMILY SSF47240 3 144 1.39E-49 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 01-11-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 7.5E-17 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 7.5E-17 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 7.5E-17 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 01-11-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 Gene3D G3DSA:1.20.1260.10 1 146 1.9E-57 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 Pfam PF00210 Ferritin-like domain 6 146 2.0E-36 T 01-11-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MLA2C4_26290 99f350f224d2a847dab11af60cbb04a4 146 PIRSF PIRSF005900 1 146 3.1E-51 T 01-11-2018 IPR002177 DNA-binding protein Dps MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 SUPERFAMILY SSF56281 126 354 3.93E-41 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 Gene3D G3DSA:3.60.15.10 119 355 7.0E-50 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 SMART SM00450 6 109 1.7E-16 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 Gene3D G3DSA:3.40.250.10 8 117 5.6E-20 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 Pfam PF00753 Metallo-beta-lactamase superfamily 130 275 4.6E-10 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 Pfam PF00581 Rhodanese-like domain 14 105 7.6E-11 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 SUPERFAMILY SSF52821 2 110 3.93E-19 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_04280 eeb797fa5b83b0c07ded6b305b2d4e4a 376 SMART SM00849 130 294 3.4E-24 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_23375 6ed65af56fbf179a8db98e83e78c641b 349 Pfam PF10646 Sporulation and spore germination 212 324 5.4E-14 T 01-11-2018 IPR019606 GerMN domain MLA2C4_23375 6ed65af56fbf179a8db98e83e78c641b 349 Pfam PF10646 Sporulation and spore germination 64 175 1.4E-20 T 01-11-2018 IPR019606 GerMN domain MLA2C4_23375 6ed65af56fbf179a8db98e83e78c641b 349 SMART SM00909 89 179 2.3E-21 T 01-11-2018 IPR019606 GerMN domain MLA2C4_23375 6ed65af56fbf179a8db98e83e78c641b 349 SMART SM00909 241 329 9.1E-19 T 01-11-2018 IPR019606 GerMN domain MLA2C4_12015 8b27612bab32e72315b15e79f19b971e 203 SUPERFAMILY SSF49842 57 189 4.97E-18 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_12015 8b27612bab32e72315b15e79f19b971e 203 Gene3D G3DSA:2.60.120.40 56 196 2.8E-10 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_17685 21a58bfa9409ef030dea546fa33c75ee 307 Gene3D G3DSA:3.40.50.720 4 281 3.4E-56 T 01-11-2018 MLA2C4_17685 21a58bfa9409ef030dea546fa33c75ee 307 SUPERFAMILY SSF51735 1 300 1.27E-58 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17685 21a58bfa9409ef030dea546fa33c75ee 307 Gene3D G3DSA:3.90.25.10 172 288 3.4E-56 T 01-11-2018 MLA2C4_17685 21a58bfa9409ef030dea546fa33c75ee 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 225 1.1E-39 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_08045 bd31f09e6e7c09efa28e7e414e2e0713 293 PIRSF PIRSF006483 1 287 6.6E-91 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_08045 bd31f09e6e7c09efa28e7e414e2e0713 293 Gene3D G3DSA:3.30.70.120 197 272 2.7E-27 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_08045 bd31f09e6e7c09efa28e7e414e2e0713 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 219 2.1E-63 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_08045 bd31f09e6e7c09efa28e7e414e2e0713 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 2.1E-22 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_27040 f0e02ff9340e584a8982d2a0c17a6af4 105 Pfam PF09685 Domain of unknown function (DUF4870) 6 98 4.1E-9 T 01-11-2018 IPR019109 Protein of unknown function DUF4870 MLA2C4_27040 f0e02ff9340e584a8982d2a0c17a6af4 105 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 104 4.0E-44 T 01-11-2018 MLA2C4_12615 19d66546c6ad0de818e78ad5ff3ed152 152 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 25 142 1.3E-10 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_12615 19d66546c6ad0de818e78ad5ff3ed152 152 SUPERFAMILY SSF160631 1 150 6.67E-18 T 01-11-2018 MLA2C4_12615 19d66546c6ad0de818e78ad5ff3ed152 152 Gene3D G3DSA:3.40.1580.10 4 150 6.4E-12 T 01-11-2018 IPR037883 Knr4/Smi1-like domain superfamily MLA2C4_12615 19d66546c6ad0de818e78ad5ff3ed152 152 SMART SM00860 25 143 3.0E-8 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_21505 7b180966b4c92fc3f0f9848527fe3b60 68 Gene3D G3DSA:3.40.5.90 2 65 4.4E-14 T 01-11-2018 MLA2C4_21505 7b180966b4c92fc3f0f9848527fe3b60 68 SMART SM00704 15 60 0.0016 T 01-11-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MLA2C4_21505 7b180966b4c92fc3f0f9848527fe3b60 68 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 55 5.1E-17 T 01-11-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 Pfam PF00005 ABC transporter 18 148 8.0E-9 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 Gene3D G3DSA:3.40.50.300 6 225 3.5E-23 T 01-11-2018 MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 PIRSF PIRSF036612 1 335 8.5E-150 T 01-11-2018 IPR012046 LytTR transcriptional regulator with ABC transporter ATP-binding domain MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 Pfam PF04397 LytTr DNA-binding domain 235 333 6.5E-25 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 SMART SM00850 235 334 2.3E-31 T 01-11-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 SUPERFAMILY SSF52540 20 199 3.43E-21 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27355 726a72526f546f69632b4e2230f4aaf6 335 Gene3D G3DSA:2.40.50.40 228 295 1.0E-13 T 01-11-2018 MLA2C4_12870 fb78c1f8564e6548df559451f367be0c 1028 Gene3D G3DSA:3.90.920.30 73 226 8.4E-10 T 01-11-2018 MLA2C4_12870 fb78c1f8564e6548df559451f367be0c 1028 SUPERFAMILY SSF52540 606 878 4.85E-9 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_12870 fb78c1f8564e6548df559451f367be0c 1028 Pfam PF01896 DNA primase small subunit 73 205 6.2E-8 T 01-11-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 MLA2C4_12870 fb78c1f8564e6548df559451f367be0c 1028 SUPERFAMILY SSF56747 4 219 1.42E-25 T 01-11-2018 MLA2C4_12870 fb78c1f8564e6548df559451f367be0c 1028 Pfam PF00493 MCM2/3/5 family 606 791 4.6E-14 T 01-11-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MLA2C4_12870 fb78c1f8564e6548df559451f367be0c 1028 Gene3D G3DSA:3.40.50.300 596 892 1.1E-17 T 01-11-2018 MLA2C4_06335 d6a2b53635161b6d6c6a96da7bd05802 311 Pfam PF00535 Glycosyl transferase family 2 11 183 8.1E-21 T 01-11-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MLA2C4_06335 d6a2b53635161b6d6c6a96da7bd05802 311 SUPERFAMILY SSF53448 8 244 1.39E-41 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_06335 d6a2b53635161b6d6c6a96da7bd05802 311 Gene3D G3DSA:3.90.550.10 1 268 8.9E-43 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_24755 a231a29f8b49f962ae0a0df81f7edea5 433 Pfam PF03929 PepSY-associated TM region 12 376 3.4E-57 T 01-11-2018 IPR005625 PepSY-associated TM protein MLA2C4_21345 e60f891c241964e0a24a11c35bea5c6e 354 Pfam PF12730 ABC-2 family transporter protein 11 178 1.2E-8 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_24615 0bf2901f14746c0f721d7562e6b8145d 687 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 212 662 1.1E-142 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 4 217 1.5E-118 T 01-11-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 1 215 50.252 T 01-11-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 Gene3D G3DSA:3.90.1470.20 14 133 1.3E-70 T 01-11-2018 MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 177 3.3E-30 T 01-11-2018 MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 SUPERFAMILY SSF56784 3 217 6.75E-55 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 Gene3D G3DSA:3.40.50.1000 5 209 1.3E-70 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 185 1.4E-51 T 01-11-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 MLA2C4_21115 dac4f0d3014d6380b33e9eeba9843726 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 176 3.9E-17 T 01-11-2018 MLA2C4_12080 46d89875295cb5d91a82d3190f67ad46 70 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 4 19 - T 01-11-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 MLA2C4_12080 46d89875295cb5d91a82d3190f67ad46 70 Pfam PF01679 Proteolipid membrane potential modulator 2 45 2.7E-11 T 01-11-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 MLA2C4_27935 7a40b3deb46b19a31f73f9933db0eaed 142 PIRSF PIRSF038931 1 141 4.5E-47 T 01-11-2018 IPR014099 Spore coat protein GerQ MLA2C4_27935 7a40b3deb46b19a31f73f9933db0eaed 142 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 53 130 7.5E-35 T 01-11-2018 IPR014099 Spore coat protein GerQ MLA2C4_27935 7a40b3deb46b19a31f73f9933db0eaed 142 Pfam PF09671 Spore coat protein (Spore_GerQ) 56 130 3.2E-35 T 01-11-2018 IPR014099 Spore coat protein GerQ MLA2C4_15400 6caf5e3f80cc2c18bb5080a1ace5ac39 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 2.2E-24 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_15400 6caf5e3f80cc2c18bb5080a1ace5ac39 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 4.1E-20 T 01-11-2018 IPR012655 Uncharacterised protein YrzI MLA2C4_20055 202c6dda506c5fff60e55dbb6ab46c6f 257 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 37.266 T 01-11-2018 IPR022898 Ribonuclease HII GO:0004523 MLA2C4_20055 202c6dda506c5fff60e55dbb6ab46c6f 257 SUPERFAMILY SSF53098 62 256 4.1E-72 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_20055 202c6dda506c5fff60e55dbb6ab46c6f 257 Pfam PF01351 Ribonuclease HII 75 249 1.3E-34 T 01-11-2018 IPR024567 Ribonuclease HII/HIII domain MLA2C4_20055 202c6dda506c5fff60e55dbb6ab46c6f 257 Gene3D G3DSA:3.30.420.10 47 257 2.1E-83 T 01-11-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MLA2C4_02725 c45ce5f48d29e3f8d73fa52f6fe2f569 86 Pfam PF14182 YgaB-like protein 3 78 8.2E-30 T 01-11-2018 IPR025572 YgaB-like protein MLA2C4_26880 51a4470ad588e8bbe3fef7cc07da0d00 280 Gene3D G3DSA:3.30.1180.10 152 280 6.3E-46 T 01-11-2018 MLA2C4_26880 51a4470ad588e8bbe3fef7cc07da0d00 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 1.3E-98 T 01-11-2018 IPR003797 DegV MLA2C4_26880 51a4470ad588e8bbe3fef7cc07da0d00 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 3.5E-105 T 01-11-2018 IPR003797 DegV MLA2C4_26880 51a4470ad588e8bbe3fef7cc07da0d00 280 SUPERFAMILY SSF82549 1 280 3.14E-96 T 01-11-2018 MLA2C4_26880 51a4470ad588e8bbe3fef7cc07da0d00 280 Gene3D G3DSA:3.40.50.10170 1 151 2.6E-52 T 01-11-2018 MLA2C4_18745 d2941a93b5580cf016294a28dd440742 47 Pfam PF13040 Fur-regulated basic protein B 2 40 9.1E-17 T 01-11-2018 IPR025004 Transcriptional regulatory protein SenN/SenS MLA2C4_26980 bfa259ff507b16db9ae3a9f8991c6ed5 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 5.2E-23 T 01-11-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MLA2C4_26980 bfa259ff507b16db9ae3a9f8991c6ed5 100 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 93 4.1E-34 T 01-11-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 MLA2C4_26980 bfa259ff507b16db9ae3a9f8991c6ed5 100 Gene3D G3DSA:3.40.50.2300 1 100 3.6E-38 T 01-11-2018 MLA2C4_26980 bfa259ff507b16db9ae3a9f8991c6ed5 100 SUPERFAMILY SSF52794 1 96 3.4E-35 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_27570 d63aa3f10a19e6b3170df792bd7476ae 152 Gene3D G3DSA:3.40.630.30 3 138 7.0E-6 T 01-11-2018 MLA2C4_27560 164c3222d03b85aa86299876ceafa773 182 Pfam PF02659 Putative manganese efflux pump 33 179 5.6E-39 T 01-11-2018 IPR003810 Putative manganese efflux pump MLA2C4_27560 164c3222d03b85aa86299876ceafa773 182 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 4 182 21.469 T 01-11-2018 IPR022929 Putative manganese efflux pump MntP MLA2C4_21710 4b831af4229f15d089c7d7b217da45a1 322 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 8.0E-53 T 01-11-2018 IPR021062 Putative aromatic acid exporter, C-terminal MLA2C4_21710 4b831af4229f15d089c7d7b217da45a1 322 Gene3D G3DSA:1.20.120.940 140 313 4.3E-52 T 01-11-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily MLA2C4_21710 4b831af4229f15d089c7d7b217da45a1 322 Pfam PF06081 Aromatic acid exporter family member 1 2 142 2.3E-51 T 01-11-2018 IPR010343 Aromatic acid exporter family member 1 MLA2C4_10955 4731379c26c69a3db49646b7aaa5598b 84 Pfam PF14201 Domain of unknown function (DUF4318) 14 84 3.0E-22 T 01-11-2018 IPR025467 Protein of unknown function DUF4318 MLA2C4_21815 bd6a12c9a74fe06208221632a9dee274 508 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 153 297 2.3E-6 T 01-11-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MLA2C4_26925 019fbc998587c00084210448a7f22239 393 PIRSF PIRSF004810 2 393 2.4E-128 T 01-11-2018 IPR014047 Chromate transporter, long chain MLA2C4_26925 019fbc998587c00084210448a7f22239 393 TIGRFAM TIGR00937 2A51: chromate efflux transporter 19 387 9.5E-142 T 01-11-2018 IPR014047 Chromate transporter, long chain MLA2C4_26925 019fbc998587c00084210448a7f22239 393 Pfam PF02417 Chromate transporter 225 386 9.9E-41 T 01-11-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MLA2C4_26925 019fbc998587c00084210448a7f22239 393 Pfam PF02417 Chromate transporter 12 177 1.3E-35 T 01-11-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 MLA2C4_18930 44955a451b0ab3e33311888c859912e5 203 SUPERFAMILY SSF53474 2 198 9.57E-58 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18930 44955a451b0ab3e33311888c859912e5 203 Gene3D G3DSA:3.40.50.1820 1 199 3.6E-49 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18930 44955a451b0ab3e33311888c859912e5 203 Pfam PF02230 Phospholipase/Carboxylesterase 6 196 5.5E-9 T 01-11-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MLA2C4_27425 03584185a65bf02a94b038841471a615 421 SUPERFAMILY SSF143243 293 418 6.93E-41 T 01-11-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27425 03584185a65bf02a94b038841471a615 421 Gene3D G3DSA:3.30.460.80 250 398 1.3E-34 T 01-11-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27425 03584185a65bf02a94b038841471a615 421 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 302 415 1.1E-36 T 01-11-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27425 03584185a65bf02a94b038841471a615 421 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 352 407 1.0E-25 T 01-11-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27425 03584185a65bf02a94b038841471a615 421 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 300 415 4.4E-40 T 01-11-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_23085 7ed62906326054ee60c692fad53e0447 652 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 8.3E-28 T 01-11-2018 IPR014248 Spore coat assembly protein SafA MLA2C4_23085 7ed62906326054ee60c692fad53e0447 652 Pfam PF01476 LysM domain 4 48 1.3E-15 T 01-11-2018 IPR018392 LysM domain MLA2C4_23085 7ed62906326054ee60c692fad53e0447 652 SUPERFAMILY SSF54106 2 48 1.96E-11 T 01-11-2018 MLA2C4_23085 7ed62906326054ee60c692fad53e0447 652 SMART SM00257 3 48 1.4E-16 T 01-11-2018 IPR018392 LysM domain MLA2C4_23085 7ed62906326054ee60c692fad53e0447 652 Gene3D G3DSA:3.10.350.10 2 59 7.7E-17 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_11290 adcb1c765cdff8578a2af9284b0411dd 215 Pfam PF00881 Nitroreductase family 10 193 1.2E-35 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_11290 adcb1c765cdff8578a2af9284b0411dd 215 Gene3D G3DSA:3.40.109.10 4 214 5.0E-54 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_11290 adcb1c765cdff8578a2af9284b0411dd 215 SUPERFAMILY SSF55469 4 213 3.66E-49 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Pfam PF03717 Penicillin-binding Protein dimerisation domain 44 196 2.7E-23 T 01-11-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Pfam PF00905 Penicillin binding protein transpeptidase domain 245 542 3.4E-82 T 01-11-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 SUPERFAMILY SSF56519 42 216 1.29E-39 T 01-11-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 SUPERFAMILY SSF54184 633 686 7.06E-11 T 01-11-2018 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Gene3D G3DSA:2.20.70.70 41 202 1.0E-44 T 01-11-2018 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Gene3D G3DSA:3.90.1310.10 45 183 1.0E-44 T 01-11-2018 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Gene3D G3DSA:3.40.710.10 210 561 2.0E-102 T 01-11-2018 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Gene3D G3DSA:3.30.70.2110 64 139 1.0E-44 T 01-11-2018 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 SUPERFAMILY SSF54184 573 631 2.88E-12 T 01-11-2018 MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Pfam PF03793 PASTA domain 578 629 1.9E-9 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 Pfam PF03793 PASTA domain 634 686 1.7E-6 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 SUPERFAMILY SSF56601 167 570 7.86E-93 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 SMART SM00740 634 688 2.5 T 01-11-2018 IPR005543 PASTA domain MLA2C4_20465 f47129d9185a03eefd50757f3ace0755 699 SMART SM00740 573 632 1.0E-6 T 01-11-2018 IPR005543 PASTA domain MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 2.7E-12 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 2.7E-12 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 2.7E-12 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 2.7E-12 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 243 263 2.7E-12 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 Pfam PF00797 N-acetyltransferase 23 263 7.8E-46 T 01-11-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 SUPERFAMILY SSF54001 2 263 2.75E-68 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_18145 50a4ac86cac056dc2677710a0471f4ad 263 Gene3D G3DSA:3.30.2140.20 1 263 1.1E-99 T 01-11-2018 MLA2C4_26770 ad73787d84ebae0e54612cd5ff17fbb0 340 Pfam PF03601 Conserved hypothetical protein 698 17 318 1.9E-84 T 01-11-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 MLA2C4_17700 ce0f6acaa072b27c8413cf02f8e338e5 273 Pfam PF00805 Pentapeptide repeats (8 copies) 202 241 2.8E-14 T 01-11-2018 IPR001646 Pentapeptide repeat MLA2C4_17700 ce0f6acaa072b27c8413cf02f8e338e5 273 SUPERFAMILY SSF141571 53 266 1.37E-25 T 01-11-2018 MLA2C4_17700 ce0f6acaa072b27c8413cf02f8e338e5 273 Gene3D G3DSA:2.160.20.100 170 262 1.6E-20 T 01-11-2018 MLA2C4_13510 fa060cd94a51a675153beb8a315a9235 246 Pfam PF12146 Serine aminopeptidase, S33 28 125 5.6E-12 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_13510 fa060cd94a51a675153beb8a315a9235 246 SUPERFAMILY SSF53474 3 238 1.36E-28 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_13510 fa060cd94a51a675153beb8a315a9235 246 Gene3D G3DSA:3.40.50.1820 6 243 4.2E-34 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_18535 b0f67957294f0c64eab5062cce112921 114 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 111 3.8E-34 T 01-11-2018 IPR018745 Domain of unknown function DUF2294 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 SUPERFAMILY SSF49401 486 579 6.96E-5 T 01-11-2018 IPR008966 Adhesion domain superfamily MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1803 1855 9.8E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2067 2119 2.3E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1139 1191 1.1E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1406 1457 8.7E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1935 1987 3.5E-17 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2199 2250 5.9E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 479 531 3.2E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 347 399 6.0E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1271 1322 9.3E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1671 1723 5.2E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1539 1591 1.9E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 743 795 2.9E-20 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 875 927 5.1E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2333 2384 1.9E-16 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 611 663 6.2E-19 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1007 1059 5.4E-18 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Gene3D G3DSA:2.60.40.740 1400 1530 3.6E-6 T 01-11-2018 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1269 1366 2.4E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 743 836 4.2E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1803 1898 2.7E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1006 1096 6.3E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 346 436 2.5E-15 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 610 704 5.0E-12 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1405 1499 6.8E-11 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1138 1232 3.0E-14 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 873 963 7.8E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1671 1766 3.0E-13 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 2331 2428 2.4E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 1935 2024 2.2E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 2067 2162 4.0E-7 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Pfam PF01345 Domain of unknown function DUF11 477 562 4.4E-10 T 01-11-2018 IPR001434 Domain of unknown function DUF11 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Gene3D G3DSA:2.60.40.740 1135 1277 3.4E-5 T 01-11-2018 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Gene3D G3DSA:2.60.40.740 470 604 2.0E-6 T 01-11-2018 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Gene3D G3DSA:2.60.40.740 729 850 9.2E-6 T 01-11-2018 MLA2C4_18410 c80478ee9808b06e7363a9347d161f41 2490 Gene3D G3DSA:2.60.40.740 341 469 2.3E-7 T 01-11-2018 MLA2C4_17925 433592b39c8b1807ce66989e38fd7d4c 93 SUPERFAMILY SSF101386 1 92 5.23E-19 T 01-11-2018 MLA2C4_17925 433592b39c8b1807ce66989e38fd7d4c 93 Gene3D G3DSA:1.10.287.1080 2 93 3.7E-20 T 01-11-2018 MLA2C4_17925 433592b39c8b1807ce66989e38fd7d4c 93 PIRSF PIRSF036521 1 92 2.2E-8 T 01-11-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related MLA2C4_17925 433592b39c8b1807ce66989e38fd7d4c 93 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 90 1.4E-6 T 01-11-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MLA2C4_23295 423f4dcd0eb9562ee10c9ae3c95fccb7 198 SUPERFAMILY SSF52540 16 192 1.75E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_23295 423f4dcd0eb9562ee10c9ae3c95fccb7 198 Pfam PF01926 50S ribosome-binding GTPase 25 143 2.1E-21 T 01-11-2018 IPR006073 GTP binding domain GO:0005525 MLA2C4_23295 423f4dcd0eb9562ee10c9ae3c95fccb7 198 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 4.7E-70 T 01-11-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MLA2C4_23295 423f4dcd0eb9562ee10c9ae3c95fccb7 198 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 27.884 T 01-11-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MLA2C4_23295 423f4dcd0eb9562ee10c9ae3c95fccb7 198 Gene3D G3DSA:3.40.50.300 1 198 3.3E-55 T 01-11-2018 MLA2C4_08995 6fe49d5014e59c3219270d6ee12fc7ac 254 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 185 252 1.7E-28 T 01-11-2018 IPR018656 Domain of unknown function DUF2087 MLA2C4_15815 7e61467d2109ec1941f44ae6cf4f1432 225 PIRSF PIRSF033101 1 139 4.8E-51 T 01-11-2018 IPR011397 Uncharacterised conserved protein UCP033101 MLA2C4_15815 7e61467d2109ec1941f44ae6cf4f1432 225 PIRSF PIRSF033101 138 225 7.7E-25 T 01-11-2018 IPR011397 Uncharacterised conserved protein UCP033101 MLA2C4_15815 7e61467d2109ec1941f44ae6cf4f1432 225 Pfam PF10086 Putative membrane peptidase family (DUF2324) 11 136 1.2E-27 T 01-11-2018 IPR011397 Uncharacterised conserved protein UCP033101 MLA2C4_15815 7e61467d2109ec1941f44ae6cf4f1432 225 Pfam PF10086 Putative membrane peptidase family (DUF2324) 138 204 3.7E-12 T 01-11-2018 IPR011397 Uncharacterised conserved protein UCP033101 MLA2C4_25315 457edb578b9a34996f99cb82339bc337 344 Gene3D G3DSA:2.160.10.10 231 341 1.1E-28 T 01-11-2018 MLA2C4_25315 457edb578b9a34996f99cb82339bc337 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 295 324 1.3E-4 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_25315 457edb578b9a34996f99cb82339bc337 344 SUPERFAMILY SSF53448 4 301 2.81E-37 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25315 457edb578b9a34996f99cb82339bc337 344 SUPERFAMILY SSF51161 196 330 1.83E-18 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_25315 457edb578b9a34996f99cb82339bc337 344 Pfam PF00483 Nucleotidyl transferase 8 149 1.7E-9 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_25315 457edb578b9a34996f99cb82339bc337 344 Gene3D G3DSA:3.90.550.10 1 157 1.2E-23 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_02950 6c3a9fac13c9f43305dd6805549ca25b 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 1.9E-93 T 01-11-2018 IPR010650 PrkA C-terminal domain MLA2C4_02950 6c3a9fac13c9f43305dd6805549ca25b 631 PIRSF PIRSF000549 1 631 1.5E-265 T 01-11-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 MLA2C4_02950 6c3a9fac13c9f43305dd6805549ca25b 631 SUPERFAMILY SSF52540 67 459 1.47E-11 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02950 6c3a9fac13c9f43305dd6805549ca25b 631 SMART SM00763 21 371 1.4E-197 T 01-11-2018 IPR013153 PrkA AAA domain MLA2C4_02950 6c3a9fac13c9f43305dd6805549ca25b 631 Pfam PF08298 PrkA AAA domain 22 369 6.2E-150 T 01-11-2018 IPR013153 PrkA AAA domain MLA2C4_27045 3383bd7d0a125970caa03007118f9dc9 163 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 2 154 1.7E-44 T 01-11-2018 IPR019250 Protein of unknown function DUF2227, metal-binding MLA2C4_28025 5d53e5ec97a5cc4368db2dc8bc341204 223 Gene3D G3DSA:2.60.120.1460 26 214 4.6E-25 T 01-11-2018 MLA2C4_28025 5d53e5ec97a5cc4368db2dc8bc341204 223 SUPERFAMILY SSF51206 28 138 1.15E-24 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like MLA2C4_28025 5d53e5ec97a5cc4368db2dc8bc341204 223 SMART SM00100 15 133 1.8E-8 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_28025 5d53e5ec97a5cc4368db2dc8bc341204 223 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 2.2E-15 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_28025 5d53e5ec97a5cc4368db2dc8bc341204 223 SUPERFAMILY SSF46785 151 219 5.44E-6 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08640 544cfe97d1e0427beae682d75b05c834 192 Pfam PF03963 Flagellar hook capping protein - N-terminal region 33 100 1.1E-17 T 01-11-2018 IPR005648 Flagellar hook capping protein MLA2C4_17130 068169d8f862efff82d6c2e2f71735a9 150 SUPERFAMILY SSF160631 9 143 3.14E-22 T 01-11-2018 MLA2C4_17130 068169d8f862efff82d6c2e2f71735a9 150 Pfam PF14568 SMI1-KNR4 cell-wall 16 140 4.6E-30 T 01-11-2018 MLA2C4_17130 068169d8f862efff82d6c2e2f71735a9 150 SMART SM00860 13 142 4.1E-9 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_17130 068169d8f862efff82d6c2e2f71735a9 150 Gene3D G3DSA:3.40.1580.10 3 146 7.5E-28 T 01-11-2018 IPR037883 Knr4/Smi1-like domain superfamily MLA2C4_14740 c1b5854b3bce596641a30d847654ba5b 159 SUPERFAMILY SSF54197 9 151 4.64E-30 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_14740 c1b5854b3bce596641a30d847654ba5b 159 Gene3D G3DSA:3.30.428.10 2 156 1.1E-31 T 01-11-2018 IPR036265 HIT-like superfamily MLA2C4_14740 c1b5854b3bce596641a30d847654ba5b 159 Pfam PF01230 HIT domain 27 114 6.6E-8 T 01-11-2018 IPR001310 Histidine triad (HIT) protein MLA2C4_13765 857be4df27de4953c3bd8f0782465de4 165 Gene3D G3DSA:3.30.240.20 75 147 1.0E-17 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_13765 857be4df27de4953c3bd8f0782465de4 165 Pfam PF04239 Protein of unknown function (DUF421) 82 154 1.9E-17 T 01-11-2018 IPR007353 Protein of unknown function DUF421 MLA2C4_23455 e601a401faf570592063342c09bbe260 275 SUPERFAMILY SSF56784 58 250 1.02E-44 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_23455 e601a401faf570592063342c09bbe260 275 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 21 245 1.5E-48 T 01-11-2018 IPR005519 Acid phosphatase, class B-like MLA2C4_23455 e601a401faf570592063342c09bbe260 275 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 9 272 1.4E-93 T 01-11-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 MLA2C4_23455 e601a401faf570592063342c09bbe260 275 PIRSF PIRSF019271 1 275 1.5E-109 T 01-11-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 MLA2C4_23455 e601a401faf570592063342c09bbe260 275 Gene3D G3DSA:3.40.50.1000 24 275 7.7E-96 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_25600 86846eb2dbf9a416714880718bdb6d37 295 Pfam PF00483 Nucleotidyl transferase 6 258 2.7E-35 T 01-11-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MLA2C4_25600 86846eb2dbf9a416714880718bdb6d37 295 Gene3D G3DSA:3.90.550.10 1 291 1.4E-95 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25600 86846eb2dbf9a416714880718bdb6d37 295 SUPERFAMILY SSF53448 5 275 7.09E-70 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_25600 86846eb2dbf9a416714880718bdb6d37 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 9.3E-123 T 01-11-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MLA2C4_27720 352749c71c1aacb299dcc19b37749cc4 244 Pfam PF12698 ABC-2 family transporter protein 50 236 4.6E-18 T 01-11-2018 MLA2C4_27720 352749c71c1aacb299dcc19b37749cc4 244 PIRSF PIRSF006648 1 243 3.8E-23 T 01-11-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 Gene3D G3DSA:3.40.50.2300 2 146 1.6E-49 T 01-11-2018 MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 140 1.5E-33 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 9.3E-9 T 01-11-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 114 129 9.3E-9 T 01-11-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 74 89 9.3E-9 T 01-11-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 SMART SM00226 2 142 6.2E-36 T 01-11-2018 IPR023485 Phosphotyrosine protein phosphatase I MLA2C4_27530 9e68b562eaf6c2144b32a7d7f7423c8f 146 SUPERFAMILY SSF52788 1 142 1.31E-40 T 01-11-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MLA2C4_03365 66ba3f173ff3e7e8b1f4eebbcccea220 228 Pfam PF02517 CAAX protease self-immunity 132 219 1.5E-19 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 13 369 1.1E-131 T 01-11-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 Pfam PF14306 PUA-like domain 21 149 5.4E-46 T 01-11-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 17 373 49.987 T 01-11-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 Pfam PF01747 ATP-sulfurylase 159 369 1.2E-94 T 01-11-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 SUPERFAMILY SSF88697 9 156 1.19E-45 T 01-11-2018 IPR015947 PUA-like superfamily MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 SUPERFAMILY SSF52374 159 370 1.63E-87 T 01-11-2018 MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 Gene3D G3DSA:3.40.50.620 160 371 1.2E-96 T 01-11-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MLA2C4_07515 9898196c4ff4b585558556e3d23fd4f7 378 Gene3D G3DSA:3.10.400.10 18 155 1.4E-43 T 01-11-2018 MLA2C4_07700 55c4ca3329a3e2c8c17afce0a26637fa 64 Pfam PF13062 Protein of unknown function (DUF3924) 1 62 1.2E-45 T 01-11-2018 IPR025038 Protein of unknown function DUF3924 MLA2C4_14735 9c2360901c7aeece115dc6f921fd59e9 274 SUPERFAMILY SSF81606 43 254 1.7E-13 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_14735 9c2360901c7aeece115dc6f921fd59e9 274 Gene3D G3DSA:3.60.40.10 21 262 2.3E-12 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_14735 9c2360901c7aeece115dc6f921fd59e9 274 Pfam PF13672 Protein phosphatase 2C 41 221 2.6E-20 T 01-11-2018 MLA2C4_05780 8e093a7d5fffc3b5f990b8bef8374230 313 Gene3D G3DSA:1.10.10.10 1 63 8.5E-14 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05780 8e093a7d5fffc3b5f990b8bef8374230 313 SUPERFAMILY SSF46785 1 60 2.53E-11 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05780 8e093a7d5fffc3b5f990b8bef8374230 313 Pfam PF08279 HTH domain 6 58 4.4E-14 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_05780 8e093a7d5fffc3b5f990b8bef8374230 313 Pfam PF13280 WYL domain 148 311 2.7E-37 T 01-11-2018 IPR026881 WYL domain MLA2C4_05780 8e093a7d5fffc3b5f990b8bef8374230 313 PIRSF PIRSF016838 1 313 1.9E-25 T 01-11-2018 IPR028349 Protein PafC MLA2C4_26815 c31efa888916c136c71a3090c6a234e8 297 PIRSF PIRSF003097 1 297 2.5E-88 T 01-11-2018 IPR004513 Cell division protein FtsX GO:0016021 MLA2C4_26815 c31efa888916c136c71a3090c6a234e8 297 Gene3D G3DSA:3.30.70.3040 47 156 1.7E-6 T 01-11-2018 MLA2C4_26815 c31efa888916c136c71a3090c6a234e8 297 Pfam PF02687 FtsX-like permease family 202 287 4.4E-6 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_27155 bffda1cddd1adf35a04f83bc673c2a0e 168 Pfam PF06338 ComK protein 7 155 1.8E-49 T 01-11-2018 IPR010461 Competence protein ComK GO:0030420 MLA2C4_27155 bffda1cddd1adf35a04f83bc673c2a0e 168 PIRSF PIRSF011560 1 164 4.1E-53 T 01-11-2018 IPR010461 Competence protein ComK GO:0030420 MLA2C4_07425 2c67dcef7c2d6123845ffcd169f64cc0 420 Gene3D G3DSA:3.30.930.10 2 325 2.8E-87 T 01-11-2018 MLA2C4_07425 2c67dcef7c2d6123845ffcd169f64cc0 420 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 13 325 3.2E-105 T 01-11-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 MLA2C4_07425 2c67dcef7c2d6123845ffcd169f64cc0 420 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 378 37.05 T 01-11-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 MLA2C4_07425 2c67dcef7c2d6123845ffcd169f64cc0 420 Pfam PF13393 Histidyl-tRNA synthetase 11 320 2.0E-72 T 01-11-2018 MLA2C4_07425 2c67dcef7c2d6123845ffcd169f64cc0 420 PIRSF PIRSF001549 2 415 7.3E-74 T 01-11-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MLA2C4_07425 2c67dcef7c2d6123845ffcd169f64cc0 420 SUPERFAMILY SSF55681 7 328 1.83E-59 T 01-11-2018 MLA2C4_25890 af34865d0688f105d1ad767392c25cd6 100 SUPERFAMILY SSF102891 1 99 4.84E-35 T 01-11-2018 IPR036493 Hypothetical protein YunC superfamily MLA2C4_25890 af34865d0688f105d1ad767392c25cd6 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 5.6E-23 T 01-11-2018 IPR014931 Protein of unknown function DUF1805 MLA2C4_25890 af34865d0688f105d1ad767392c25cd6 100 Gene3D G3DSA:3.30.1980.10 1 100 3.4E-24 T 01-11-2018 IPR036493 Hypothetical protein YunC superfamily MLA2C4_06410 f4da9235a66dceaca457d5cad69125c0 119 Pfam PF07098 Protein of unknown function (DUF1360) 11 112 1.4E-37 T 01-11-2018 IPR010773 Mycobacterium phage PG1, Gp7 MLA2C4_16280 644a9402747e4d238a38ca8ee12ccb00 292 Gene3D G3DSA:3.30.200.20 6 94 5.2E-12 T 01-11-2018 MLA2C4_16280 644a9402747e4d238a38ca8ee12ccb00 292 Pfam PF01636 Phosphotransferase enzyme family 31 254 1.7E-33 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_16280 644a9402747e4d238a38ca8ee12ccb00 292 SUPERFAMILY SSF56112 12 262 4.32E-47 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_16280 644a9402747e4d238a38ca8ee12ccb00 292 Gene3D G3DSA:3.90.1200.10 99 285 3.5E-22 T 01-11-2018 MLA2C4_17970 a08971d16052a1a4d3a54ac6c53fdd18 148 Pfam PF04657 Putative inner membrane exporter, YdcZ 10 144 1.2E-29 T 01-11-2018 IPR006750 Putative inner membrane exporter, YdcZ MLA2C4_12430 6100051055709d09719a9e5348b89a8f 49 Pfam PF09388 Spo0E like sporulation regulatory protein 6 46 1.5E-12 T 01-11-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 MLA2C4_12430 6100051055709d09719a9e5348b89a8f 49 SUPERFAMILY SSF140500 1 48 9.42E-14 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_12430 6100051055709d09719a9e5348b89a8f 49 Gene3D G3DSA:1.20.58.990 1 49 3.4E-18 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 6.7E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 6.7E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 6.7E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 6.7E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 Pfam PF01047 MarR family 36 93 8.4E-12 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 Gene3D G3DSA:1.10.10.10 1 139 4.6E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 SMART SM00347 29 128 5.8E-16 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_07335 a4601645e889b03e0568a805db5cc7d2 139 SUPERFAMILY SSF46785 7 138 1.19E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_21745 b5bb12d4ac66b42519e58d11a3caa5c8 234 Pfam PF04239 Protein of unknown function (DUF421) 98 211 6.2E-27 T 01-11-2018 IPR007353 Protein of unknown function DUF421 MLA2C4_21745 b5bb12d4ac66b42519e58d11a3caa5c8 234 Gene3D G3DSA:3.30.240.20 90 164 6.6E-19 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_21745 b5bb12d4ac66b42519e58d11a3caa5c8 234 Gene3D G3DSA:3.30.240.20 179 234 7.8E-6 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_26140 2689c2b8fb291843ec46db8db371ea3f 260 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 248 7.1E-61 T 01-11-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_26140 2689c2b8fb291843ec46db8db371ea3f 260 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 251 30.156 T 01-11-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 MLA2C4_26140 2689c2b8fb291843ec46db8db371ea3f 260 PRINTS PR00701 60kDa inner membrane protein signature 128 151 2.0E-13 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_26140 2689c2b8fb291843ec46db8db371ea3f 260 PRINTS PR00701 60kDa inner membrane protein signature 214 237 2.0E-13 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_26140 2689c2b8fb291843ec46db8db371ea3f 260 Pfam PF02096 60Kd inner membrane protein 61 248 1.6E-54 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_14540 cc8956a1c443ee6dc6970fd4532418d5 284 SUPERFAMILY SSF53474 2 279 2.03E-57 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_14540 cc8956a1c443ee6dc6970fd4532418d5 284 Pfam PF00561 alpha/beta hydrolase fold 24 267 5.5E-21 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_14540 cc8956a1c443ee6dc6970fd4532418d5 284 Gene3D G3DSA:3.40.50.1820 1 283 9.6E-61 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_14540 cc8956a1c443ee6dc6970fd4532418d5 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.8E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_14540 cc8956a1c443ee6dc6970fd4532418d5 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 2.8E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_14540 cc8956a1c443ee6dc6970fd4532418d5 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.8E-9 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_17595 b24771b4f135656639494bf758326130 82 Pfam PF04226 Transglycosylase associated protein 33 77 1.3E-9 T 01-11-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MLA2C4_18080 2fe2879ddcb8ad45a1f1d6ef0181421e 158 SUPERFAMILY SSF109854 14 155 5.86E-24 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_18080 2fe2879ddcb8ad45a1f1d6ef0181421e 158 Gene3D G3DSA:1.20.120.450 2 157 4.8E-15 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_18080 2fe2879ddcb8ad45a1f1d6ef0181421e 158 Pfam PF12867 DinB superfamily 16 148 6.0E-20 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_18360 712d2b2fe398dec964578aa130eb03c3 363 Pfam PF13037 Domain of unknown function (DUF3898) 261 350 5.1E-43 T 01-11-2018 IPR025012 Domain of unknown function DUF3898 MLA2C4_18360 712d2b2fe398dec964578aa130eb03c3 363 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 2.2E-136 T 01-11-2018 IPR025006 Protein of unknown function DUF3900 MLA2C4_15750 a0b4ac1a9e93ae9153927c0cd4c17e50 554 PIRSF PIRSF010386 7 553 1.0E-240 T 01-11-2018 IPR012166 Uncharacterised protein family RocB MLA2C4_15750 a0b4ac1a9e93ae9153927c0cd4c17e50 554 Gene3D G3DSA:3.40.630.10 12 238 6.0E-40 T 01-11-2018 MLA2C4_15750 a0b4ac1a9e93ae9153927c0cd4c17e50 554 SUPERFAMILY SSF53187 14 530 1.23E-33 T 01-11-2018 MLA2C4_15750 a0b4ac1a9e93ae9153927c0cd4c17e50 554 Pfam PF01546 Peptidase family M20/M25/M40 117 447 1.5E-12 T 01-11-2018 IPR002933 Peptidase M20 GO:0016787 MLA2C4_21455 7b8777fdfbed55f42be40ee509a26ed0 87 Pfam PF13025 Protein of unknown function (DUF3886) 19 85 1.9E-21 T 01-11-2018 IPR024980 Protein of unknown function DUF3886 MLA2C4_19340 4b10aed3da57884570d3594ca511fcf9 220 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 29 218 2.5E-54 T 01-11-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MLA2C4_19340 4b10aed3da57884570d3594ca511fcf9 220 Pfam PF13614 AAA domain 48 177 1.9E-14 T 01-11-2018 IPR025669 AAA domain MLA2C4_19340 4b10aed3da57884570d3594ca511fcf9 220 Gene3D G3DSA:3.40.50.300 2 219 3.6E-68 T 01-11-2018 MLA2C4_19340 4b10aed3da57884570d3594ca511fcf9 220 SUPERFAMILY SSF52540 47 218 3.73E-37 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 Gene3D G3DSA:3.90.1150.10 6 390 2.6E-188 T 01-11-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 01-11-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 Pfam PF00464 Serine hydroxymethyltransferase 4 380 2.4E-180 T 01-11-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 Gene3D G3DSA:3.40.640.10 33 283 2.6E-188 T 01-11-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 53.726 T 01-11-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 PIRSF PIRSF000412 1 413 2.9E-170 T 01-11-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MLA2C4_27515 ffc819791362bfd5f75f644a554d00b4 413 SUPERFAMILY SSF53383 2 411 4.13E-183 T 01-11-2018 IPR015424 Pyridoxal phosphate-dependent transferase MLA2C4_18390 5739459a4403b497151505736f3c8725 206 Pfam PF01184 GPR1/FUN34/yaaH family 8 197 2.7E-23 T 01-11-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 MLA2C4_08585 c943dd2670c0d2604c37ae555bae27e1 122 Gene3D G3DSA:1.20.120.340 1 121 6.4E-14 T 01-11-2018 MLA2C4_08585 c943dd2670c0d2604c37ae555bae27e1 122 SUPERFAMILY SSF101116 2 120 1.83E-21 T 01-11-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 MLA2C4_08585 c943dd2670c0d2604c37ae555bae27e1 122 Pfam PF02561 Flagellar protein FliS 5 116 3.2E-18 T 01-11-2018 IPR003713 Flagellar protein FliS GO:0044780 MLA2C4_23005 345bf9ee44336901aeb4062e90012172 94 Pfam PF13797 Post-transcriptional regulator 8 90 8.8E-32 T 01-11-2018 IPR025716 Post-transcriptional regulator MLA2C4_15880 960189424568b69eb3812a8fc40169f1 485 SUPERFAMILY SSF103473 20 443 3.66E-76 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_15880 960189424568b69eb3812a8fc40169f1 485 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_15880 960189424568b69eb3812a8fc40169f1 485 Pfam PF07690 Major Facilitator Superfamily 57 380 1.7E-38 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_15880 960189424568b69eb3812a8fc40169f1 485 Gene3D G3DSA:1.20.1250.20 22 458 4.4E-71 T 01-11-2018 MLA2C4_17020 f5a8eabf26a56b3e52eeb192a5543856 208 SUPERFAMILY SSF46785 3 156 7.09E-21 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17020 f5a8eabf26a56b3e52eeb192a5543856 208 SMART SM00418 12 127 6.5E-4 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_17020 f5a8eabf26a56b3e52eeb192a5543856 208 Pfam PF01022 Bacterial regulatory protein, arsR family 19 64 9.1E-8 T 01-11-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MLA2C4_17020 f5a8eabf26a56b3e52eeb192a5543856 208 Gene3D G3DSA:1.10.10.10 6 85 2.0E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_10865 41c564b2524b16bda5cb993b5b3206d5 122 Gene3D G3DSA:1.10.443.10 1 122 2.0E-20 T 01-11-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MLA2C4_10865 41c564b2524b16bda5cb993b5b3206d5 122 Pfam PF00589 Phage integrase family 2 109 2.7E-13 T 01-11-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MLA2C4_10865 41c564b2524b16bda5cb993b5b3206d5 122 SUPERFAMILY SSF56349 2 120 2.56E-24 T 01-11-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MLA2C4_06905 aad9780f252573a713ab2cf912bf64a8 324 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 238 274 1.4E-7 T 01-11-2018 IPR011964 YVTN beta-propeller repeat MLA2C4_06905 aad9780f252573a713ab2cf912bf64a8 324 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 283 315 1.8E-7 T 01-11-2018 IPR011964 YVTN beta-propeller repeat MLA2C4_06905 aad9780f252573a713ab2cf912bf64a8 324 Gene3D G3DSA:2.130.10.10 226 316 1.8E-13 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MLA2C4_06905 aad9780f252573a713ab2cf912bf64a8 324 SUPERFAMILY SSF51004 29 313 2.56E-45 T 01-11-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily MLA2C4_06905 aad9780f252573a713ab2cf912bf64a8 324 Gene3D G3DSA:2.130.10.10 25 209 6.3E-15 T 01-11-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MLA2C4_22910 bb8943f14524fa603f89e3e23e88e76f 42 Pfam PF13056 Protein of unknown function (DUF3918) 3 42 1.1E-19 T 01-11-2018 IPR025029 Protein of unknown function DUF3918 MLA2C4_17615 809ef985c19f7c05b98daaa9227a5a67 180 Gene3D G3DSA:1.10.3300.10 70 173 4.8E-12 T 01-11-2018 IPR023286 ABATE domain superfamily MLA2C4_17615 809ef985c19f7c05b98daaa9227a5a67 180 Pfam PF11706 CGNR zinc finger 124 172 1.8E-19 T 01-11-2018 IPR021005 Zinc finger, CGNR MLA2C4_17615 809ef985c19f7c05b98daaa9227a5a67 180 SUPERFAMILY SSF160904 4 171 6.41E-29 T 01-11-2018 MLA2C4_23390 376811866f28c6dddd16370e44e4916a 227 SUPERFAMILY SSF52317 1 223 3.88E-69 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_23390 376811866f28c6dddd16370e44e4916a 227 Gene3D G3DSA:3.40.50.880 2 225 5.5E-68 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_23390 376811866f28c6dddd16370e44e4916a 227 Pfam PF01965 DJ-1/PfpI family 28 214 1.3E-9 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_24460 d62f1d2a94142a915cb9b02bb634352d 181 Pfam PF02834 LigT like Phosphoesterase 10 92 4.0E-14 T 01-11-2018 IPR014051 Phosphoesterase, HXTX MLA2C4_24460 d62f1d2a94142a915cb9b02bb634352d 181 Pfam PF02834 LigT like Phosphoesterase 99 171 4.7E-10 T 01-11-2018 IPR014051 Phosphoesterase, HXTX MLA2C4_24460 d62f1d2a94142a915cb9b02bb634352d 181 SUPERFAMILY SSF55144 3 180 2.09E-40 T 01-11-2018 IPR009097 Cyclic phosphodiesterase MLA2C4_24460 d62f1d2a94142a915cb9b02bb634352d 181 Gene3D G3DSA:3.90.1140.10 4 181 1.9E-42 T 01-11-2018 MLA2C4_24460 d62f1d2a94142a915cb9b02bb634352d 181 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 4 179 1.6E-54 T 01-11-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 MLA2C4_24460 d62f1d2a94142a915cb9b02bb634352d 181 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 179 22.441 T 01-11-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 MLA2C4_10395 ad67c005b1d6c8db253a8fb363995705 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 27 2.3E-13 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_10395 ad67c005b1d6c8db253a8fb363995705 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 25 2.9E-14 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_10605 ec1eecc35e49991078ea414afe138f5a 370 Pfam PF00149 Calcineurin-like phosphoesterase 14 208 1.4E-13 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_10605 ec1eecc35e49991078ea414afe138f5a 370 Gene3D G3DSA:3.60.21.10 8 251 9.7E-41 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_10605 ec1eecc35e49991078ea414afe138f5a 370 SUPERFAMILY SSF56300 10 204 6.33E-34 T 01-11-2018 MLA2C4_00870 f06e0564a7e0244e2f10984821bd996c 203 PIRSF PIRSF029886 1 199 3.3E-79 T 01-11-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 MLA2C4_00870 f06e0564a7e0244e2f10984821bd996c 203 SMART SM01251 17 196 1.3E-120 T 01-11-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 MLA2C4_00870 f06e0564a7e0244e2f10984821bd996c 203 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 195 2.7E-79 T 01-11-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 MLA2C4_01230 01fa11699c5cde4b9494e10e70608a4d 501 Pfam PF16800 IseA DL-endopeptidase inhibitor 353 496 1.8E-15 T 01-11-2018 IPR031841 DL-endopeptidase inhibitor IseA MLA2C4_01230 01fa11699c5cde4b9494e10e70608a4d 501 Pfam PF16472 Domain of unknown function (DUF5050) 60 326 4.1E-17 T 01-11-2018 IPR032485 Domain of unknown function DUF5050 MLA2C4_01230 01fa11699c5cde4b9494e10e70608a4d 501 Gene3D G3DSA:3.10.450.420 395 496 4.0E-5 T 01-11-2018 MLA2C4_00580 e54669d8bbc1fab05cd290f296b37e74 170 Pfam PF05991 YacP-like NYN domain 5 167 8.8E-54 T 01-11-2018 IPR010298 Protein of unknown function DUF901 MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 SUPERFAMILY SSF88659 91 171 5.23E-10 T 01-11-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 Pfam PF04542 Sigma-70 region 2 19 84 6.0E-6 T 01-11-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 168 2.8E-17 T 01-11-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 Gene3D G3DSA:1.10.1740.10 4 111 8.9E-9 T 01-11-2018 MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 SUPERFAMILY SSF88946 15 99 1.22E-13 T 01-11-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 Pfam PF08281 Sigma-70, region 4 116 165 3.5E-11 T 01-11-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MLA2C4_14505 5660ee7539853b680f81ccc1f6111e7f 176 Gene3D G3DSA:1.10.10.10 112 174 3.9E-9 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 SMART SM00382 33 241 1.3E-17 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 2.6E-19 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 297 6.9E-15 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 Pfam PF00005 ABC transporter 25 183 5.7E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 SUPERFAMILY SSF52540 4 254 3.55E-74 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_06230 096db44fb4bfa3456e2706ff82a81a32 347 Gene3D G3DSA:3.40.50.300 1 330 2.8E-103 T 01-11-2018 MLA2C4_12455 92b0cd493e60a3dd138255907300ef73 61 Pfam PF14169 Cold-inducible protein YdjO 4 60 5.5E-28 T 01-11-2018 IPR025916 Cold-inducible protein YdjO MLA2C4_05300 2f78aa37bfd2f17c45e6bf91d86d0983 83 Pfam PF04226 Transglycosylase associated protein 33 78 4.7E-11 T 01-11-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 SUPERFAMILY SSF54826 1 125 1.56E-37 T 01-11-2018 MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 Gene3D G3DSA:3.20.20.120 116 350 4.5E-146 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 Gene3D G3DSA:3.30.390.10 1 356 4.5E-146 T 01-11-2018 IPR029017 Enolase-like, N-terminal MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 Pfam PF13378 Enolase C-terminal domain-like 144 356 4.6E-48 T 01-11-2018 IPR029065 Enolase C-terminal domain-like MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 SUPERFAMILY SSF51604 112 363 1.09E-67 T 01-11-2018 IPR036849 Enolase-like, C-terminal domain superfamily MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 124 2.6E-24 T 01-11-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MLA2C4_02000 b26c0e131db53bbcbef1a9a9f4f365ab 369 SMART SM00922 142 239 8.6E-28 T 01-11-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MLA2C4_11045 a1cde17dbad164de8031fef573727e43 90 Pfam PF06013 Proteins of 100 residues with WXG 4 88 1.6E-20 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_11045 a1cde17dbad164de8031fef573727e43 90 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 4.0E-24 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_11045 a1cde17dbad164de8031fef573727e43 90 Gene3D G3DSA:1.10.287.850 1 90 4.3E-33 T 01-11-2018 MLA2C4_11045 a1cde17dbad164de8031fef573727e43 90 SUPERFAMILY SSF158414 5 80 8.76E-22 T 01-11-2018 IPR029013 HP0062-like domain superfamily MLA2C4_07480 5bc881046776ba602d61fcc6432315b0 326 SUPERFAMILY SSF51735 101 287 3.09E-58 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_07480 5bc881046776ba602d61fcc6432315b0 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 319 1.6E-36 T 01-11-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MLA2C4_07480 5bc881046776ba602d61fcc6432315b0 326 SUPERFAMILY SSF52283 5 139 1.89E-35 T 01-11-2018 MLA2C4_07480 5bc881046776ba602d61fcc6432315b0 326 Gene3D G3DSA:3.40.50.720 6 314 3.2E-121 T 01-11-2018 MLA2C4_07480 5bc881046776ba602d61fcc6432315b0 326 Gene3D G3DSA:3.40.50.720 99 288 3.2E-121 T 01-11-2018 MLA2C4_07480 5bc881046776ba602d61fcc6432315b0 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 287 1.0E-59 T 01-11-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MLA2C4_09520 e11957b642512f35a2038b643c4eb6a3 147 Pfam PF13673 Acetyltransferase (GNAT) domain 46 129 8.7E-17 T 01-11-2018 IPR000182 GNAT domain MLA2C4_09520 e11957b642512f35a2038b643c4eb6a3 147 Gene3D G3DSA:3.40.630.30 1 139 1.7E-20 T 01-11-2018 MLA2C4_09520 e11957b642512f35a2038b643c4eb6a3 147 SUPERFAMILY SSF55729 1 135 2.29E-23 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_18250 b301dd29259245276f2a3bbe503b3373 167 Gene3D G3DSA:3.40.630.30 1 165 9.7E-36 T 01-11-2018 MLA2C4_18250 b301dd29259245276f2a3bbe503b3373 167 Pfam PF13302 Acetyltransferase (GNAT) domain 8 147 1.0E-21 T 01-11-2018 IPR000182 GNAT domain MLA2C4_18250 b301dd29259245276f2a3bbe503b3373 167 SUPERFAMILY SSF55729 2 153 1.68E-33 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_16905 451ecd3a75e2a41a253aeb3b6ccb2f4d 107 Gene3D G3DSA:3.10.450.40 33 107 6.4E-6 T 01-11-2018 MLA2C4_22225 5cc1d594dc76c63f850d989c4aef0235 124 Gene3D G3DSA:3.40.50.450 1 124 1.7E-9 T 01-11-2018 MLA2C4_22225 5cc1d594dc76c63f850d989c4aef0235 124 SUPERFAMILY SSF52309 1 92 7.94E-8 T 01-11-2018 MLA2C4_22225 5cc1d594dc76c63f850d989c4aef0235 124 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 10 92 3.8E-8 T 01-11-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 MLA2C4_13515 f0e3cd6825e9497665cbdd3f0d419bd8 152 SUPERFAMILY SSF109854 3 136 8.06E-34 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_13515 f0e3cd6825e9497665cbdd3f0d419bd8 152 Gene3D G3DSA:1.20.120.450 1 152 4.5E-45 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_13515 f0e3cd6825e9497665cbdd3f0d419bd8 152 Pfam PF05163 DinB family 3 146 2.4E-31 T 01-11-2018 IPR007837 DNA damage-inducible protein DinB MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 SUPERFAMILY SSF46894 128 227 1.84E-22 T 01-11-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 Gene3D G3DSA:3.40.50.2300 2 121 3.9E-32 T 01-11-2018 MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 Gene3D G3DSA:1.10.10.10 124 228 4.6E-24 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.4E-20 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 SMART SM00448 2 112 1.7E-35 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-24 T 01-11-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 SMART SM00862 149 225 1.3E-18 T 01-11-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MLA2C4_25165 f941d9cc807c73f0ac04200ce96c171d 231 SUPERFAMILY SSF52172 1 123 6.83E-35 T 01-11-2018 IPR011006 CheY-like superfamily MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 Gene3D G3DSA:3.30.565.10 475 605 7.3E-24 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 Gene3D G3DSA:3.30.450.40 298 389 8.9E-7 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 511 604 1.7E-6 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 SUPERFAMILY SSF55874 467 603 1.7E-14 T 01-11-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 Pfam PF07730 Histidine kinase 403 467 3.7E-15 T 01-11-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 SMART SM00387 508 606 1.5E-4 T 01-11-2018 IPR003594 Histidine kinase/HSP90-like ATPase MLA2C4_03345 03587167c2c5e3598779a21928c93366 610 SUPERFAMILY SSF55781 262 393 2.4E-9 T 01-11-2018 MLA2C4_10000 184fbcdad50822e6f4520cffe733d2e8 202 Pfam PF00293 NUDIX domain 31 142 3.7E-7 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_10000 184fbcdad50822e6f4520cffe733d2e8 202 Gene3D G3DSA:3.90.79.10 1 176 2.0E-32 T 01-11-2018 MLA2C4_10000 184fbcdad50822e6f4520cffe733d2e8 202 SUPERFAMILY SSF55811 3 162 4.46E-23 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_07145 8a89e329077c079e26e0f7df8a8cf7a7 192 Pfam PF00583 Acetyltransferase (GNAT) family 50 165 3.3E-14 T 01-11-2018 IPR000182 GNAT domain MLA2C4_07145 8a89e329077c079e26e0f7df8a8cf7a7 192 Gene3D G3DSA:3.40.630.30 1 190 6.2E-43 T 01-11-2018 MLA2C4_07145 8a89e329077c079e26e0f7df8a8cf7a7 192 SUPERFAMILY SSF55729 2 183 6.56E-25 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21470 31dc6e27ca728fb2a86196e08eb19f44 332 Gene3D G3DSA:3.40.50.1820 23 325 1.3E-40 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_21470 31dc6e27ca728fb2a86196e08eb19f44 332 Pfam PF00561 alpha/beta hydrolase fold 47 156 8.5E-16 T 01-11-2018 IPR000073 Alpha/beta hydrolase fold-1 MLA2C4_21470 31dc6e27ca728fb2a86196e08eb19f44 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 125 139 7.3E-9 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_21470 31dc6e27ca728fb2a86196e08eb19f44 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 7.3E-9 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_21470 31dc6e27ca728fb2a86196e08eb19f44 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 77 88 7.3E-9 T 01-11-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MLA2C4_21470 31dc6e27ca728fb2a86196e08eb19f44 332 SUPERFAMILY SSF53474 40 321 3.13E-37 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_03250 4728c0d431a203a799eec48127ad6b29 352 SUPERFAMILY SSF81345 15 348 2.35E-82 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_03250 4728c0d431a203a799eec48127ad6b29 352 Pfam PF01032 FecCD transport family 33 348 1.0E-92 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_03250 4728c0d431a203a799eec48127ad6b29 352 Gene3D G3DSA:1.10.3470.10 19 352 1.2E-99 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_24085 29bdbef15e1a77931fec3cae448701b6 211 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 12 155 7.8E-15 T 01-11-2018 IPR014903 Protein of unknown function DUF1796 MLA2C4_28340 c80a01896c82331fd96f53dba14bbd12 438 Pfam PF07435 YycH protein 4 414 3.1E-71 T 01-11-2018 IPR009996 Regulatory protein YycH MLA2C4_28340 c80a01896c82331fd96f53dba14bbd12 438 Gene3D G3DSA:3.30.310.160 223 359 2.9E-40 T 01-11-2018 MLA2C4_28340 c80a01896c82331fd96f53dba14bbd12 438 Gene3D G3DSA:3.10.450.310 201 406 2.9E-40 T 01-11-2018 MLA2C4_14425 34df4bc119dc52732a099acf0ea2b0ca 122 Pfam PF13788 Domain of unknown function (DUF4180) 10 118 5.8E-43 T 01-11-2018 IPR025438 Domain of unknown function DUF4180 MLA2C4_14420 2412c5df7a944c1bce62ccb7a27261dd 174 PIRSF PIRSF032285 9 174 5.3E-70 T 01-11-2018 IPR011235 MepB-like MLA2C4_14420 2412c5df7a944c1bce62ccb7a27261dd 174 Pfam PF08877 MepB protein 36 157 4.9E-50 T 01-11-2018 IPR011235 MepB-like MLA2C4_14420 2412c5df7a944c1bce62ccb7a27261dd 174 Gene3D G3DSA:3.40.1350.140 13 167 3.2E-58 T 01-11-2018 IPR038231 MepB-like superfamily MLA2C4_22210 ef205a21efde99341d7fd170ab193ca9 71 Pfam PF13051 Protein of unknown function (DUF3912) 2 69 2.3E-44 T 01-11-2018 IPR025023 Protein of unknown function DUF3912 MLA2C4_03405 fcb493d3ceed73553ed30fe93a620491 125 SUPERFAMILY SSF82784 4 123 2.22E-25 T 01-11-2018 IPR036102 OsmC/Ohr superfamily MLA2C4_03405 fcb493d3ceed73553ed30fe93a620491 125 Pfam PF02566 OsmC-like protein 22 118 7.5E-21 T 01-11-2018 IPR003718 OsmC/Ohr family MLA2C4_03405 fcb493d3ceed73553ed30fe93a620491 125 Gene3D G3DSA:3.30.300.20 2 124 8.8E-28 T 01-11-2018 IPR015946 K homology domain-like, alpha/beta MLA2C4_07930 f06e51eea78d330b18ddf022d5d38515 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 3.0E-30 T 01-11-2018 IPR020076 Protein of unknown function DUF2768 MLA2C4_07930 f06e51eea78d330b18ddf022d5d38515 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 3.8E-25 T 01-11-2018 IPR020076 Protein of unknown function DUF2768 MLA2C4_11255 53eefa9620fd69ea5de67304a40cf056 154 SUPERFAMILY SSF49764 29 146 4.71E-27 T 01-11-2018 IPR008978 HSP20-like chaperone MLA2C4_11255 53eefa9620fd69ea5de67304a40cf056 154 Gene3D G3DSA:2.60.40.790 7 152 2.4E-28 T 01-11-2018 IPR008978 HSP20-like chaperone MLA2C4_11255 53eefa9620fd69ea5de67304a40cf056 154 Pfam PF00011 Hsp20/alpha crystallin family 57 148 1.9E-15 T 01-11-2018 IPR002068 Alpha crystallin/Hsp20 domain MLA2C4_09830 7dc0e37719e44d64044b0c8280aeeea2 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 18 284 8.5E-33 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_10800 107af28f5631ed5f70025fd8b41444f0 404 Pfam PF01882 Protein of unknown function DUF58 206 277 2.6E-19 T 01-11-2018 IPR002881 Domain of unknown function DUF58 MLA2C4_21660 fab89cb7194c149785f3c59543c39bc2 83 Pfam PF13068 Protein of unknown function (DUF3932) 1 81 1.8E-55 T 01-11-2018 IPR025173 Protein of unknown function DUF3932 MLA2C4_25665 d3e0237a37367cfe0fe2ebe13fa0ced5 395 SUPERFAMILY SSF103473 9 381 2.09E-58 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_25665 d3e0237a37367cfe0fe2ebe13fa0ced5 395 Gene3D G3DSA:1.20.1250.20 5 380 2.4E-48 T 01-11-2018 MLA2C4_25665 d3e0237a37367cfe0fe2ebe13fa0ced5 395 Pfam PF07690 Major Facilitator Superfamily 16 319 3.5E-38 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_06810 bb0e66c0e33d62d3a7bcca43b78d3c8f 259 Pfam PF13256 Domain of unknown function (DUF4047) 28 152 1.6E-60 T 01-11-2018 IPR025120 Domain of unknown function DUF4047 MLA2C4_03430 384466d57f2b8c36aa15adb66f53618c 173 Pfam PF01872 RibD C-terminal domain 4 164 1.6E-21 T 01-11-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MLA2C4_03430 384466d57f2b8c36aa15adb66f53618c 173 SUPERFAMILY SSF53597 3 170 7.07E-37 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MLA2C4_03430 384466d57f2b8c36aa15adb66f53618c 173 Gene3D G3DSA:3.40.430.10 1 173 1.2E-47 T 01-11-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 SMART SM00382 240 378 3.4E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 Gene3D G3DSA:3.40.50.300 237 422 4.3E-52 T 01-11-2018 MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 10 330 1.1E-55 T 01-11-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 Pfam PF00448 SRP54-type protein, GTPase domain 243 433 1.1E-39 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 SMART SM00962 241 434 3.2E-40 T 01-11-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 SUPERFAMILY SSF52540 239 420 6.52E-29 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_08730 2e8ce3749b034ac05bb8c0812473cdda 436 Gene3D G3DSA:1.20.120.1380 187 424 4.3E-52 T 01-11-2018 MLA2C4_16410 fe45b170e0815d13e42311106e57de42 471 PIRSF PIRSF006060 5 469 3.2E-91 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_16410 fe45b170e0815d13e42311106e57de42 471 Gene3D G3DSA:1.20.1740.10 20 468 6.8E-125 T 01-11-2018 MLA2C4_16410 fe45b170e0815d13e42311106e57de42 471 Pfam PF13520 Amino acid permease 26 441 1.0E-61 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_14345 eee9751f6cf2c512c0b7369d05dca35f 173 Pfam PF12867 DinB superfamily 32 164 1.9E-14 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_14345 eee9751f6cf2c512c0b7369d05dca35f 173 SUPERFAMILY SSF109854 3 173 6.26E-50 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_14345 eee9751f6cf2c512c0b7369d05dca35f 173 Gene3D G3DSA:1.20.120.450 1 173 2.2E-51 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_14345 eee9751f6cf2c512c0b7369d05dca35f 173 Hamap MF_01256 Putative metal-dependent hydrolase . 2 173 40.957 T 01-11-2018 IPR023774 Putative metal-dependent hydrolase YfiT MLA2C4_13705 0494ea4dc4a3379c485afe1b3ce2b306 250 Gene3D G3DSA:3.90.1200.10 83 238 7.8E-11 T 01-11-2018 MLA2C4_13705 0494ea4dc4a3379c485afe1b3ce2b306 250 Pfam PF01636 Phosphotransferase enzyme family 43 212 8.0E-14 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_13705 0494ea4dc4a3379c485afe1b3ce2b306 250 SUPERFAMILY SSF56112 6 227 3.04E-28 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_08380 fce46f3b6d56d5d7e5fd1dbedd485db7 210 Pfam PF01810 LysE type translocator 13 204 4.6E-31 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_10655 0cf182c045aa0d7e63fb0004fc0331e5 298 Gene3D G3DSA:1.10.287.850 1 89 2.0E-25 T 01-11-2018 MLA2C4_10655 0cf182c045aa0d7e63fb0004fc0331e5 298 Pfam PF06013 Proteins of 100 residues with WXG 4 88 1.9E-21 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_10655 0cf182c045aa0d7e63fb0004fc0331e5 298 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 88 3.9E-25 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_10655 0cf182c045aa0d7e63fb0004fc0331e5 298 SUPERFAMILY SSF140453 3 88 9.68E-19 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 SUPERFAMILY SSF118215 7 398 1.96E-120 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 291 314 - T 01-11-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 PRINTS PR00173 Glutamate-aspartate symporter signature 1 21 4.3E-33 T 01-11-2018 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 PRINTS PR00173 Glutamate-aspartate symporter signature 323 342 4.3E-33 T 01-11-2018 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 PRINTS PR00173 Glutamate-aspartate symporter signature 42 62 4.3E-33 T 01-11-2018 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 PRINTS PR00173 Glutamate-aspartate symporter signature 72 97 4.3E-33 T 01-11-2018 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 PRINTS PR00173 Glutamate-aspartate symporter signature 288 314 4.3E-33 T 01-11-2018 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 PRINTS PR00173 Glutamate-aspartate symporter signature 141 163 4.3E-33 T 01-11-2018 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 34 49 - T 01-11-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 Pfam PF00375 Sodium:dicarboxylate symporter family 7 396 4.1E-116 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MLA2C4_18610 36ffe951dc829c08fbf4c7351ed9c303 420 Gene3D G3DSA:1.10.3860.10 2 416 2.9E-128 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_27170 ce67b1c11e05f1f6f4495cd3295af7bc 400 Pfam PF12704 MacB-like periplasmic core domain 21 239 7.3E-32 T 01-11-2018 IPR025857 MacB-like periplasmic core domain MLA2C4_27170 ce67b1c11e05f1f6f4495cd3295af7bc 400 Pfam PF02687 FtsX-like permease family 306 393 1.3E-14 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 1.2E-76 T 01-11-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 41.851 T 01-11-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 01-11-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 01-11-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 Pfam PF01227 GTP cyclohydrolase I 9 186 1.9E-79 T 01-11-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 Gene3D G3DSA:3.30.1130.10 55 189 2.2E-60 T 01-11-2018 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 Gene3D G3DSA:1.10.286.10 1 54 2.1E-22 T 01-11-2018 MLA2C4_07950 1e369f1dfdccbc7639c83489f751bbec 189 SUPERFAMILY SSF55620 3 187 3.78E-77 T 01-11-2018 MLA2C4_10505 7a0f40851fd07c5d3087b5161e9d9c94 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 140 7.0E-22 T 01-11-2018 IPR002810 NfeD-like, C-terminal domain MLA2C4_10505 7a0f40851fd07c5d3087b5161e9d9c94 142 SUPERFAMILY SSF141322 79 139 1.31E-16 T 01-11-2018 MLA2C4_10505 7a0f40851fd07c5d3087b5161e9d9c94 142 Gene3D G3DSA:2.40.50.140 78 142 8.5E-19 T 01-11-2018 MLA2C4_08620 5c10a8dd4b7474f5a8fe8f047bca8873 228 Pfam PF02108 Flagellar assembly protein FliH 83 197 3.9E-9 T 01-11-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE MLA2C4_01815 021d169b383f9ae5583606cb9a3abd9c 281 Gene3D G3DSA:3.30.479.30 85 216 3.1E-10 T 01-11-2018 MLA2C4_01815 021d169b383f9ae5583606cb9a3abd9c 281 SMART SM00244 49 214 3.1E-11 T 01-11-2018 IPR001107 Band 7 domain MLA2C4_01815 021d169b383f9ae5583606cb9a3abd9c 281 SUPERFAMILY SSF117892 87 217 1.96E-12 T 01-11-2018 IPR036013 Band 7/SPFH domain superfamily MLA2C4_01815 021d169b383f9ae5583606cb9a3abd9c 281 Pfam PF01145 SPFH domain / Band 7 family 53 228 1.3E-22 T 01-11-2018 IPR001107 Band 7 domain MLA2C4_22950 ffeac7938ea2167f4c577f8721e8ff1d 213 Pfam PF13921 Myb-like DNA-binding domain 8 62 2.7E-5 T 01-11-2018 MLA2C4_22950 ffeac7938ea2167f4c577f8721e8ff1d 213 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 84 4.0E-45 T 01-11-2018 IPR014243 Transcription factor, RsfA MLA2C4_03460 8c7e60293bfcad9585627e60efaa1a4c 41 Pfam PF13219 Protein of unknown function (DUF4027) 4 39 3.1E-24 T 01-11-2018 IPR025104 Protein of unknown function DUF4027 MLA2C4_14825 a755208fda7b93ce2bd6764bdeb02771 117 Pfam PF04237 YjbR 9 102 6.1E-24 T 01-11-2018 IPR007351 Uncharacterised protein YjbR MLA2C4_14825 a755208fda7b93ce2bd6764bdeb02771 117 SUPERFAMILY SSF142906 3 115 7.72E-39 T 01-11-2018 IPR038056 YjbR-like superfamily MLA2C4_14825 a755208fda7b93ce2bd6764bdeb02771 117 Gene3D G3DSA:3.90.1150.30 1 117 6.1E-41 T 01-11-2018 IPR038056 YjbR-like superfamily MLA2C4_07830 a91578a1f2a975e2eaeead8159724416 159 Pfam PF01476 LysM domain 104 149 2.6E-12 T 01-11-2018 IPR018392 LysM domain MLA2C4_07830 a91578a1f2a975e2eaeead8159724416 159 Gene3D G3DSA:3.10.350.10 88 159 1.1E-15 T 01-11-2018 IPR036779 LysM domain superfamily MLA2C4_07830 a91578a1f2a975e2eaeead8159724416 159 SMART SM00257 103 149 2.2E-10 T 01-11-2018 IPR018392 LysM domain MLA2C4_07830 a91578a1f2a975e2eaeead8159724416 159 SUPERFAMILY SSF54106 102 149 1.31E-8 T 01-11-2018 MLA2C4_18655 e0ed82d4a2892b9d01f5a427a9ac8ce8 147 SUPERFAMILY SSF54593 5 144 8.16E-22 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18655 e0ed82d4a2892b9d01f5a427a9ac8ce8 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 140 4.3E-9 T 01-11-2018 IPR028973 PhnB-like MLA2C4_18655 e0ed82d4a2892b9d01f5a427a9ac8ce8 147 Gene3D G3DSA:3.10.180.10 1 146 2.6E-26 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 Pfam PF00326 Prolyl oligopeptidase family 446 643 3.9E-41 T 01-11-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 Gene3D G3DSA:2.120.10.30 156 309 1.8E-5 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 Gene3D G3DSA:2.120.10.30 10 155 1.6E-18 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 26 112 1.6E-4 T 01-11-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 SUPERFAMILY SSF53474 387 642 5.75E-59 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 Gene3D G3DSA:3.40.50.1820 344 644 1.2E-62 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_00980 04fd6c833318114c029d3e212afdb92f 655 SUPERFAMILY SSF82171 19 356 1.83E-33 T 01-11-2018 MLA2C4_06350 3584b9cd2b8f718d19af9656d561beb4 292 Gene3D G3DSA:2.60.120.40 158 292 4.1E-62 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 332 3.9E-166 T 01-11-2018 IPR006377 Catabolite control protein A GO:0006355 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 Gene3D G3DSA:1.10.260.40 1 60 2.8E-29 T 01-11-2018 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 Gene3D G3DSA:3.40.50.2300 63 310 1.9E-94 T 01-11-2018 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 SMART SM00354 2 72 1.2E-39 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 Pfam PF13377 Periplasmic binding protein-like domain 170 331 3.6E-37 T 01-11-2018 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 SUPERFAMILY SSF53822 62 332 5.3E-91 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.8E-19 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 01-11-2018 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 SUPERFAMILY SSF47413 2 60 8.44E-20 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.3E-6 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.3E-6 T 01-11-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MLA2C4_24305 091f6759d1dd50751e24b21c273887ee 332 Gene3D G3DSA:3.40.50.2300 161 291 1.9E-94 T 01-11-2018 MLA2C4_22360 6182f0c3f119b8d5a6dc4f74c0c68ba4 123 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 122 2.0E-45 T 01-11-2018 IPR020506 Uncharacterised protein family YqfZ MLA2C4_25230 737c0c1549900df38093c8e6497f1198 409 Gene3D G3DSA:2.120.10.30 186 388 2.1E-6 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_25230 737c0c1549900df38093c8e6497f1198 409 Gene3D G3DSA:2.120.10.30 30 182 6.3E-9 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_25230 737c0c1549900df38093c8e6497f1198 409 SUPERFAMILY SSF82171 37 348 1.06E-23 T 01-11-2018 MLA2C4_28480 497e9c4a1564a7769e7dd6a69b2e8e50 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.359 T 01-11-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28480 497e9c4a1564a7769e7dd6a69b2e8e50 44 Pfam PF00468 Ribosomal protein L34 1 44 2.8E-24 T 01-11-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28480 497e9c4a1564a7769e7dd6a69b2e8e50 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-16 T 01-11-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28480 497e9c4a1564a7769e7dd6a69b2e8e50 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 8.4E-22 T 01-11-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28480 497e9c4a1564a7769e7dd6a69b2e8e50 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 01-11-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MLA2C4_17860 8adeb7a50148d3f6b4f61057bc16064a 217 Pfam PF02517 CAAX protease self-immunity 125 212 9.2E-13 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_15935 ce5701278932e68f675b078f0ee34ca1 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 2.8E-18 T 01-11-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MLA2C4_15935 ce5701278932e68f675b078f0ee34ca1 97 SUPERFAMILY SSF54909 1 92 8.26E-26 T 01-11-2018 IPR011008 Dimeric alpha-beta barrel MLA2C4_15935 ce5701278932e68f675b078f0ee34ca1 97 Gene3D G3DSA:3.30.70.100 1 95 1.6E-26 T 01-11-2018 MLA2C4_12020 e7fcd0fac1a02917ea6e8a487c25856b 64 Gene3D G3DSA:2.60.40.3750 1 64 1.4E-43 T 01-11-2018 MLA2C4_14385 72bf20690f2f1a35e983f26cfc114d7e 476 Gene3D G3DSA:2.120.10.30 1 416 8.3E-27 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_14385 72bf20690f2f1a35e983f26cfc114d7e 476 Pfam PF07995 Glucose / Sorbosone dehydrogenase 74 277 1.8E-10 T 01-11-2018 IPR012938 Glucose/Sorbosone dehydrogenase MLA2C4_14385 72bf20690f2f1a35e983f26cfc114d7e 476 SUPERFAMILY SSF50952 71 316 1.31E-11 T 01-11-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MLA2C4_18235 6cb6d9c2fde2ac9a75c8b63574a07f59 322 Gene3D G3DSA:1.20.1530.20 1 307 1.5E-104 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_18235 6cb6d9c2fde2ac9a75c8b63574a07f59 322 Pfam PF01758 Sodium Bile acid symporter family 41 220 4.3E-40 T 01-11-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 SUPERFAMILY SSF53807 16 314 8.34E-86 T 01-11-2018 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 Gene3D G3DSA:3.40.50.1980 25 203 2.1E-61 T 01-11-2018 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00690 Adhesin family signature 65 78 7.8E-12 T 01-11-2018 IPR006128 Adhesion lipoprotein GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00690 Adhesin family signature 34 52 7.8E-12 T 01-11-2018 IPR006128 Adhesion lipoprotein GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00690 Adhesin family signature 78 95 7.8E-12 T 01-11-2018 IPR006128 Adhesion lipoprotein GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00690 Adhesin family signature 201 222 7.8E-12 T 01-11-2018 IPR006128 Adhesion lipoprotein GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 Gene3D G3DSA:3.40.50.1980 204 316 3.1E-38 T 01-11-2018 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 314 1.3E-79 T 01-11-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00691 Adhesin B signature 34 55 4.0E-10 T 01-11-2018 IPR006129 Adhesin B GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00691 Adhesin B signature 294 312 4.0E-10 T 01-11-2018 IPR006129 Adhesin B GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00691 Adhesin B signature 59 77 4.0E-10 T 01-11-2018 IPR006129 Adhesin B GO:0007155 MLA2C4_10305 c5be56720a5ffaba1800476374139cab 316 PRINTS PR00691 Adhesin B signature 145 164 4.0E-10 T 01-11-2018 IPR006129 Adhesin B GO:0007155 MLA2C4_13625 d1ecf03de4223413115af38cb6260fea 476 SUPERFAMILY SSF53098 30 473 5.69E-65 T 01-11-2018 IPR012337 Ribonuclease H-like superfamily MLA2C4_13625 d1ecf03de4223413115af38cb6260fea 476 Pfam PF01609 Transposase DDE domain 120 382 4.0E-45 T 01-11-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MLA2C4_24695 130577c6b78a5282866150166dbd4147 87 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 6.3E-35 T 01-11-2018 IPR019668 Uncharacterised protein family YtzC MLA2C4_15190 299dfc71b2f3699d63f947ef7bd42253 150 Pfam PF07552 Spore Coat Protein X and V domain 92 149 1.4E-21 T 01-11-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 MLA2C4_15190 299dfc71b2f3699d63f947ef7bd42253 150 Pfam PF07552 Spore Coat Protein X and V domain 29 85 5.2E-20 T 01-11-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 MLA2C4_04100 47dcbf449b37f09095c2ee1e80e1386a 360 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 359 2.2E-91 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_04100 47dcbf449b37f09095c2ee1e80e1386a 360 Gene3D G3DSA:3.30.300.210 216 359 9.0E-13 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_04100 47dcbf449b37f09095c2ee1e80e1386a 360 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 194 357 2.7E-23 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 Hamap MF_00838 Diadenylate cyclase [dacB]. 14 201 35.994 T 01-11-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 Gene3D G3DSA:1.10.287.770 1 69 5.1E-41 T 01-11-2018 MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 PIRSF PIRSF004793 1 201 3.1E-64 T 01-11-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 Gene3D G3DSA:3.40.1700.10 70 201 2.7E-52 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 79 195 5.8E-40 T 01-11-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 1 69 8.3E-27 T 01-11-2018 IPR019457 Uncharacterised domain YojJ, N-terminal MLA2C4_25610 511c7090e3118968e62414b0a00b1b64 201 SUPERFAMILY SSF143597 28 198 3.4E-52 T 01-11-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily MLA2C4_27145 42652b57607ba0177e22b517ef4f9d72 71 Pfam PF11148 Protein of unknown function (DUF2922) 3 66 1.1E-17 T 01-11-2018 IPR021321 Protein of unknown function DUF2922 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 3.4E-22 T 01-11-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 SUPERFAMILY SSF55008 1 67 9.16E-22 T 01-11-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 01-11-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 Pfam PF00403 Heavy-metal-associated domain 5 66 1.6E-19 T 01-11-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 Gene3D G3DSA:3.30.70.100 1 68 5.5E-29 T 01-11-2018 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 PRINTS PR00944 Copper ion binding protein signature 15 28 1.1E-5 T 01-11-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 PRINTS PR00944 Copper ion binding protein signature 54 67 1.1E-5 T 01-11-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 PRINTS PR00944 Copper ion binding protein signature 28 41 1.1E-5 T 01-11-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 MLA2C4_19485 f269785a7b79f9d40fb27c33f8d4e20b 68 PRINTS PR00944 Copper ion binding protein signature 3 15 1.1E-5 T 01-11-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 MLA2C4_04960 dd760f7d1ee7850af8e14cb1b5545a56 679 Pfam PF04411 PD-(D/E)XK nuclease superfamily 377 480 2.5E-6 T 01-11-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 Hamap MF_00740 Phosphopentomutase [deoB]. 4 389 57.407 T 01-11-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 Pfam PF01676 Metalloenzyme superfamily 5 380 4.6E-44 T 01-11-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 PIRSF PIRSF001491 3 393 5.4E-170 T 01-11-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 SUPERFAMILY SSF143856 101 217 7.98E-53 T 01-11-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 Gene3D G3DSA:3.40.720.10 5 389 6.5E-180 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 387 7.5E-205 T 01-11-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 SUPERFAMILY SSF53649 3 392 1.26E-79 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_21390 5077b8931c6eb74d99c165a734f59579 394 Gene3D G3DSA:3.30.70.1250 99 217 6.5E-180 T 01-11-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MLA2C4_22740 9256c85dc347f1b870f1fd72fec4408d 104 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 93 5.7E-23 T 01-11-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MLA2C4_22740 9256c85dc347f1b870f1fd72fec4408d 104 Gene3D G3DSA:3.30.1360.20 3 101 2.2E-29 T 01-11-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MLA2C4_22740 9256c85dc347f1b870f1fd72fec4408d 104 SUPERFAMILY SSF55248 4 94 1.96E-25 T 01-11-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MLA2C4_27345 16307e19ecf0a4d5784f1c0787397cc0 234 Pfam PF12698 ABC-2 family transporter protein 50 223 3.9E-11 T 01-11-2018 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 241 5.1E-68 T 01-11-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 Pfam PF02096 60Kd inner membrane protein 59 241 7.7E-61 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 PRINTS PR00701 60kDa inner membrane protein signature 124 147 2.7E-15 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 PRINTS PR00701 60kDa inner membrane protein signature 208 231 2.7E-15 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 PRINTS PR01900 YidC translocation/secretion protein signature 175 190 9.2E-6 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 PRINTS PR01900 YidC translocation/secretion protein signature 197 221 9.2E-6 T 01-11-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 MLA2C4_28470 fedb16b944580add52ca2a6f1d14e975 255 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 246 33.275 T 01-11-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 MLA2C4_22770 e66722404504db9700f7a55c88c54d19 174 SUPERFAMILY SSF55729 7 157 2.05E-35 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_22770 e66722404504db9700f7a55c88c54d19 174 Gene3D G3DSA:3.40.630.30 2 174 6.0E-40 T 01-11-2018 MLA2C4_22770 e66722404504db9700f7a55c88c54d19 174 Pfam PF13302 Acetyltransferase (GNAT) domain 12 152 2.1E-29 T 01-11-2018 IPR000182 GNAT domain MLA2C4_24285 893f4509627d6157a91ceff79d95fe3c 90 Pfam PF13055 Protein of unknown function (DUF3917) 18 88 1.2E-45 T 01-11-2018 IPR025027 Protein of unknown function DUF3917 MLA2C4_04070 6e0584d347616804e336b4a4ae30b632 71 Pfam PF07561 Domain of Unknown Function (DUF1540) 4 67 2.5E-13 T 01-11-2018 IPR011437 Domain of unknown function DUF1540 MLA2C4_25870 d3b0ba314ce3f08da18ee4a5c9b3c8bf 160 Pfam PF04073 Aminoacyl-tRNA editing domain 44 142 8.2E-21 T 01-11-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_25870 d3b0ba314ce3f08da18ee4a5c9b3c8bf 160 Gene3D G3DSA:3.90.960.10 1 156 4.0E-32 T 01-11-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_25870 d3b0ba314ce3f08da18ee4a5c9b3c8bf 160 SUPERFAMILY SSF55826 2 144 2.88E-34 T 01-11-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MLA2C4_02210 6a1323fd47a9e0e77b523c60d62b9262 941 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 720 921 1.7E-49 T 01-11-2018 IPR017501 Phage infection protein, YhgE, C-terminal MLA2C4_02210 6a1323fd47a9e0e77b523c60d62b9262 941 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 173 3.6E-49 T 01-11-2018 IPR017500 Phage infection protein, YhgE, N-terminal MLA2C4_02210 6a1323fd47a9e0e77b523c60d62b9262 941 Pfam PF01061 ABC-2 type transporter 773 889 5.9E-9 T 01-11-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MLA2C4_04015 639569ea887b069851b93358779d79fe 153 SUPERFAMILY SSF46785 30 152 1.07E-18 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_04015 639569ea887b069851b93358779d79fe 153 SMART SM00347 34 137 2.1E-13 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_04015 639569ea887b069851b93358779d79fe 153 Gene3D G3DSA:1.10.10.10 1 152 7.8E-23 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_04015 639569ea887b069851b93358779d79fe 153 Pfam PF01047 MarR family 42 98 8.7E-9 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_27225 af0f7485c1ae357fe481a82991b25845 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 253 8.0E-57 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_27225 af0f7485c1ae357fe481a82991b25845 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 327 7.8E-131 T 01-11-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MLA2C4_27225 af0f7485c1ae357fe481a82991b25845 330 Gene3D G3DSA:3.90.25.10 174 320 1.1E-134 T 01-11-2018 MLA2C4_27225 af0f7485c1ae357fe481a82991b25845 330 SUPERFAMILY SSF51735 1 329 3.36E-96 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_27225 af0f7485c1ae357fe481a82991b25845 330 Gene3D G3DSA:3.40.50.720 4 256 1.1E-134 T 01-11-2018 MLA2C4_27645 17e595699aa3ffa0a639be48bea4572d 176 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 92 2.5E-34 T 01-11-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 MLA2C4_27645 17e595699aa3ffa0a639be48bea4572d 176 Gene3D G3DSA:1.10.10.1250 2 82 1.2E-33 T 01-11-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily MLA2C4_27645 17e595699aa3ffa0a639be48bea4572d 176 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 1.2E-10 T 01-11-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 MLA2C4_27645 17e595699aa3ffa0a639be48bea4572d 176 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 175 14.856 T 01-11-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 MLA2C4_07905 0e7eb9a9ca5704e6d2e77927e4ea226f 297 Pfam PF14045 YIEGIA protein 8 288 8.6E-124 T 01-11-2018 IPR025918 YIEGIA protein MLA2C4_07905 0e7eb9a9ca5704e6d2e77927e4ea226f 297 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 281 2.0E-140 T 01-11-2018 MLA2C4_24550 e39528e035c9dab95473f6d7f7e167d5 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 1.8E-23 T 01-11-2018 MLA2C4_24550 e39528e035c9dab95473f6d7f7e167d5 77 SUPERFAMILY SSF54285 1 77 2.8E-18 T 01-11-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MLA2C4_24550 e39528e035c9dab95473f6d7f7e167d5 77 Pfam PF02597 ThiS family 4 77 7.2E-17 T 01-11-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MLA2C4_24550 e39528e035c9dab95473f6d7f7e167d5 77 Gene3D G3DSA:3.10.20.30 1 77 3.1E-22 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_24555 9c3bc53a2a8c6afb7c95b691c68d6297 154 Pfam PF02391 MoaE protein 11 119 6.0E-35 T 01-11-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MLA2C4_24555 9c3bc53a2a8c6afb7c95b691c68d6297 154 SUPERFAMILY SSF54690 6 138 3.14E-46 T 01-11-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MLA2C4_24555 9c3bc53a2a8c6afb7c95b691c68d6297 154 Gene3D G3DSA:3.90.1170.40 3 145 3.2E-52 T 01-11-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MLA2C4_11900 5e8828942f45538504f91ad3eabaceea 651 Pfam PF00246 Zinc carboxypeptidase 115 252 3.2E-13 T 01-11-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MLA2C4_11900 5e8828942f45538504f91ad3eabaceea 651 SUPERFAMILY SSF53187 68 335 4.63E-28 T 01-11-2018 MLA2C4_11900 5e8828942f45538504f91ad3eabaceea 651 Gene3D G3DSA:3.40.630.10 66 345 7.2E-23 T 01-11-2018 MLA2C4_11900 5e8828942f45538504f91ad3eabaceea 651 SMART SM00631 66 329 5.6E-4 T 01-11-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MLA2C4_11900 5e8828942f45538504f91ad3eabaceea 651 SUPERFAMILY SSF53187 376 483 1.79E-5 T 01-11-2018 MLA2C4_09280 f7cda2e570f74781cbed00329395a0c3 421 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 208 3.0E-11 T 01-11-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MLA2C4_09280 f7cda2e570f74781cbed00329395a0c3 421 SUPERFAMILY SSF55347 132 372 1.06E-29 T 01-11-2018 MLA2C4_09280 f7cda2e570f74781cbed00329395a0c3 421 Gene3D G3DSA:3.40.50.720 2 127 1.2E-24 T 01-11-2018 MLA2C4_09280 f7cda2e570f74781cbed00329395a0c3 421 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 124 1.1E-16 T 01-11-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MLA2C4_09280 f7cda2e570f74781cbed00329395a0c3 421 SUPERFAMILY SSF51735 2 154 3.47E-35 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 Gene3D G3DSA:1.10.287.80 6 281 3.2E-102 T 01-11-2018 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 285 4.3E-108 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 Gene3D G3DSA:3.40.1380.10 61 204 3.2E-102 T 01-11-2018 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 7.9E-40 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 7.9E-40 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 7.9E-40 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 7.9E-40 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 SUPERFAMILY SSF52943 2 285 1.23E-90 T 01-11-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 01-11-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 285 35.967 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_27465 c558de247d358c48d9e7d90dcfa61d94 286 Pfam PF00231 ATP synthase 3 285 9.9E-100 T 01-11-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MLA2C4_08595 4fdd83449a7f7444786f2bb330c66a7f 138 Pfam PF00460 Flagella basal body rod protein 23 38 5.7E-7 T 01-11-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MLA2C4_08595 4fdd83449a7f7444786f2bb330c66a7f 138 PIRSF PIRSF002889 11 137 1.1E-18 T 01-11-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MLA2C4_08595 4fdd83449a7f7444786f2bb330c66a7f 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 01-11-2018 IPR019776 Flagellar basal body rod protein, conserved site MLA2C4_08595 4fdd83449a7f7444786f2bb330c66a7f 138 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 12 130 9.2E-21 T 01-11-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MLA2C4_02135 25dcbf476624a0a1b5aebc46ece231e4 260 Pfam PF10127 Predicted nucleotidyltransferase 1 249 1.2E-95 T 01-11-2018 IPR018775 Nucleotidyltransferase, predicted MLA2C4_03085 95900bbfe701132d75dd43e7a6dd10ef 174 Pfam PF16167 Domain of unknown function (DUF4871) 44 171 4.2E-84 T 01-11-2018 IPR032366 Protein of unknown function DUF4871 MLA2C4_03085 95900bbfe701132d75dd43e7a6dd10ef 174 Gene3D G3DSA:2.60.40.3830 36 174 2.6E-55 T 01-11-2018 MLA2C4_28165 0bd1b96e6c219eadf17079798b43a382 347 Pfam PF01594 AI-2E family transporter 16 333 6.3E-45 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like MLA2C4_18345 b4d001570e5183e003934705bac7ab76 222 SUPERFAMILY SSF161098 13 209 1.83E-42 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_18345 b4d001570e5183e003934705bac7ab76 222 Gene3D G3DSA:1.10.3720.10 2 219 9.8E-54 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_18345 b4d001570e5183e003934705bac7ab76 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 112 1.3E-25 T 01-11-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 MLA2C4_18345 b4d001570e5183e003934705bac7ab76 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 217 2.5E-20 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_07695 a2fe4816fe13ff2a400ef171f078ada4 281 Gene3D G3DSA:3.20.20.410 1 280 4.4E-93 T 01-11-2018 IPR036520 UPF0759 superfamily MLA2C4_07695 a2fe4816fe13ff2a400ef171f078ada4 281 SUPERFAMILY SSF117396 2 267 1.15E-84 T 01-11-2018 IPR036520 UPF0759 superfamily MLA2C4_07695 a2fe4816fe13ff2a400ef171f078ada4 281 Pfam PF01904 Protein of unknown function DUF72 21 264 2.5E-58 T 01-11-2018 IPR002763 Protein of unknown function DUF72 MLA2C4_00145 b9d55cae6ad22dc5e17b3286d77eb6c0 89 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 3.3E-29 T 01-11-2018 IPR010001 SigmaK-factor processing regulatory BofA MLA2C4_00145 b9d55cae6ad22dc5e17b3286d77eb6c0 89 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 84 1.2E-19 T 01-11-2018 IPR010001 SigmaK-factor processing regulatory BofA MLA2C4_16180 7a5a04b74b50ca26245df795f25fc954 329 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 324 8.9E-96 T 01-11-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MLA2C4_16180 7a5a04b74b50ca26245df795f25fc954 329 SMART SM00797 24 317 3.3E-138 T 01-11-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MLA2C4_16180 7a5a04b74b50ca26245df795f25fc954 329 Gene3D G3DSA:2.40.100.10 190 326 1.3E-49 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_16180 7a5a04b74b50ca26245df795f25fc954 329 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 300 6.3E-87 T 01-11-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MLA2C4_16180 7a5a04b74b50ca26245df795f25fc954 329 SUPERFAMILY SSF50891 193 307 2.09E-12 T 01-11-2018 IPR029000 Cyclophilin-like domain superfamily MLA2C4_17665 ff8e9eb7eea428735b8fa285585097c3 264 Pfam PF13704 Glycosyl transferase family 2 17 102 2.6E-8 T 01-11-2018 MLA2C4_25995 21fe7e1427115151070b9847fedfedf5 337 Pfam PF13303 Phosphotransferase system, EIIC 11 333 2.6E-101 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_08360 bb9897e95430af562a425cd23d81b20c 58 Pfam PF10782 Zinc-finger 2 58 2.6E-28 T 01-11-2018 IPR019718 Protein of unknown function DUF2602 MLA2C4_02900 d9841554d6db83495bc726e8d54723b1 258 Pfam PF00912 Transglycosylase 60 217 1.1E-60 T 01-11-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_02900 d9841554d6db83495bc726e8d54723b1 258 SUPERFAMILY SSF53955 60 239 2.39E-69 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_02900 d9841554d6db83495bc726e8d54723b1 258 Gene3D G3DSA:1.10.3810.10 61 243 1.6E-78 T 01-11-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_05150 6cf52aff2f18bd4eecf8d6671a49a161 216 Pfam PF04892 VanZ like family 43 161 1.2E-23 T 01-11-2018 IPR006976 VanZ-like MLA2C4_26960 47abd9154f9d54f9f41374e4c8f3e08a 123 SUPERFAMILY SSF56276 5 116 3.27E-39 T 01-11-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 MLA2C4_26960 47abd9154f9d54f9f41374e4c8f3e08a 123 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 29.113 T 01-11-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MLA2C4_26960 47abd9154f9d54f9f41374e4c8f3e08a 123 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 4.9E-42 T 01-11-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MLA2C4_26960 47abd9154f9d54f9f41374e4c8f3e08a 123 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 1.2E-35 T 01-11-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 MLA2C4_26960 47abd9154f9d54f9f41374e4c8f3e08a 123 Gene3D G3DSA:3.60.90.10 1 122 9.8E-43 T 01-11-2018 MLA2C4_14125 8add228703011cf0bf8a6a696a0313cf 167 Pfam PF04229 GrpB protein 5 163 7.5E-45 T 01-11-2018 IPR007344 GrpB/Dephospho-CoA kinase MLA2C4_14125 8add228703011cf0bf8a6a696a0313cf 167 Gene3D G3DSA:3.30.460.10 1 167 1.1E-49 T 01-11-2018 MLA2C4_14125 8add228703011cf0bf8a6a696a0313cf 167 SUPERFAMILY SSF81301 7 166 3.6E-47 T 01-11-2018 MLA2C4_16640 706946e65176536bb18145d22c46944f 341 SUPERFAMILY SSF53474 67 340 8.56E-41 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16640 706946e65176536bb18145d22c46944f 341 Gene3D G3DSA:3.40.50.1820 54 341 2.9E-56 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16640 706946e65176536bb18145d22c46944f 341 Pfam PF07859 alpha/beta hydrolase fold 99 306 1.9E-24 T 01-11-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 MLA2C4_26910 e2542d47e2cdcf8530c399813d238bd5 245 Pfam PF01522 Polysaccharide deacetylase 44 164 1.0E-26 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_26910 e2542d47e2cdcf8530c399813d238bd5 245 SUPERFAMILY SSF88713 44 229 4.7E-51 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_26910 e2542d47e2cdcf8530c399813d238bd5 245 Gene3D G3DSA:3.20.20.370 29 236 2.0E-56 T 01-11-2018 MLA2C4_19315 3c706759f6638ef0eee5821db93b9eb7 354 Pfam PF14897 EpsG family 37 341 1.1E-53 T 01-11-2018 MLA2C4_10440 af8e9a101d93e40f9fc84f11ec95d10c 215 Gene3D G3DSA:3.10.580.10 1 124 3.5E-20 T 01-11-2018 MLA2C4_10440 af8e9a101d93e40f9fc84f11ec95d10c 215 SUPERFAMILY SSF54631 1 121 2.78E-20 T 01-11-2018 MLA2C4_10440 af8e9a101d93e40f9fc84f11ec95d10c 215 PIRSF PIRSF035040 1 208 1.6E-87 T 01-11-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type MLA2C4_10440 af8e9a101d93e40f9fc84f11ec95d10c 215 Pfam PF00571 CBS domain 77 120 0.008 T 01-11-2018 IPR000644 CBS domain MLA2C4_10440 af8e9a101d93e40f9fc84f11ec95d10c 215 Pfam PF00571 CBS domain 9 59 1.4E-6 T 01-11-2018 IPR000644 CBS domain MLA2C4_11430 80ae4873f1cce1d556d55559628481cb 198 Gene3D G3DSA:3.40.630.30 35 172 1.8E-7 T 01-11-2018 MLA2C4_11430 80ae4873f1cce1d556d55559628481cb 198 SUPERFAMILY SSF55729 29 150 3.29E-13 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_27320 dafe5b8114f7d0b693b329bd512f49be 144 Pfam PF07977 FabA-like domain 11 134 7.2E-35 T 01-11-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_27320 dafe5b8114f7d0b693b329bd512f49be 144 Gene3D G3DSA:3.10.129.10 1 144 3.3E-59 T 01-11-2018 MLA2C4_27320 dafe5b8114f7d0b693b329bd512f49be 144 SUPERFAMILY SSF54637 1 139 6.71E-48 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_27320 dafe5b8114f7d0b693b329bd512f49be 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 139 9.2E-58 T 01-11-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_27320 dafe5b8114f7d0b693b329bd512f49be 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.67 T 01-11-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MLA2C4_14875 a7873e2e5f37dd3c21beb0e9328b3fe5 110 Pfam PF06108 Protein of unknown function (DUF952) 6 93 7.0E-22 T 01-11-2018 IPR009297 Protein of unknown function DUF952 MLA2C4_14875 a7873e2e5f37dd3c21beb0e9328b3fe5 110 Gene3D G3DSA:3.20.170.20 1 109 3.3E-28 T 01-11-2018 MLA2C4_14875 a7873e2e5f37dd3c21beb0e9328b3fe5 110 SUPERFAMILY SSF56399 2 104 2.13E-27 T 01-11-2018 MLA2C4_05765 3fbbd1405e6ad2cc5491976e106e3b70 101 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 22 87 9.7E-22 T 01-11-2018 IPR018656 Domain of unknown function DUF2087 MLA2C4_10785 e172e7c9fe28cb1c3b0126aba0750fdd 69 Pfam PF13063 Protein of unknown function (DUF3925) 1 65 5.8E-48 T 01-11-2018 IPR025168 Protein of unknown function DUF3925 MLA2C4_21920 61bf10ae63daf3cb1fff844fed65582f 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 68 121 8.0E-20 T 01-11-2018 IPR025664 Stage III sporulation protein AC/AD family MLA2C4_21920 61bf10ae63daf3cb1fff844fed65582f 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 1 53 1.2E-8 T 01-11-2018 IPR025664 Stage III sporulation protein AC/AD family MLA2C4_21920 61bf10ae63daf3cb1fff844fed65582f 127 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 124 2.8E-36 T 01-11-2018 IPR014211 Stage III sporulation protein AD MLA2C4_06295 f3fb1174acc916de222f954c78c1bc16 192 SUPERFAMILY SSF55154 5 186 5.72E-30 T 01-11-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 MLA2C4_06295 f3fb1174acc916de222f954c78c1bc16 192 SMART SM01118 4 190 9.4E-22 T 01-11-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MLA2C4_06295 f3fb1174acc916de222f954c78c1bc16 192 PIRSF PIRSF012526 1 191 8.5E-75 T 01-11-2018 IPR009195 Uncharacterised protein family YjbK MLA2C4_06295 f3fb1174acc916de222f954c78c1bc16 192 Gene3D G3DSA:2.40.320.10 1 190 1.2E-51 T 01-11-2018 MLA2C4_06295 f3fb1174acc916de222f954c78c1bc16 192 Pfam PF01928 CYTH domain 4 184 1.2E-30 T 01-11-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MLA2C4_21145 2b34fd6664fe461be410bd5520850856 377 SUPERFAMILY SSF56601 60 363 7.04E-77 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_21145 2b34fd6664fe461be410bd5520850856 377 Gene3D G3DSA:3.40.710.10 61 365 8.8E-81 T 01-11-2018 MLA2C4_21145 2b34fd6664fe461be410bd5520850856 377 Pfam PF00144 Beta-lactamase 78 361 7.8E-55 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 Gene3D G3DSA:3.40.50.970 370 561 5.2E-59 T 01-11-2018 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 SUPERFAMILY SSF52518 12 182 4.32E-53 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 SUPERFAMILY SSF52467 195 360 4.03E-35 T 01-11-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 SUPERFAMILY SSF52518 375 552 1.18E-58 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 Gene3D G3DSA:3.40.50.970 2 191 3.1E-69 T 01-11-2018 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 181 2.8E-55 T 01-11-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 01-11-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 542 3.4E-43 T 01-11-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 16 553 1.6E-264 T 01-11-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 333 3.8E-27 T 01-11-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MLA2C4_04715 08dc110eab65ffebd1998ac4df31fae5 562 Gene3D G3DSA:3.40.50.1220 192 366 1.5E-37 T 01-11-2018 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 Gene3D G3DSA:3.40.50.1400 148 287 1.0E-99 T 01-11-2018 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 Hamap MF_00323 Ferrochelatase [hemH]. 4 306 31.499 T 01-11-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 Pfam PF00762 Ferrochelatase 5 305 3.9E-80 T 01-11-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 TIGRFAM TIGR00109 hemH: ferrochelatase 2 306 1.9E-90 T 01-11-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 SUPERFAMILY SSF53800 3 305 5.89E-87 T 01-11-2018 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 ProSitePatterns PS00534 Ferrochelatase signature. 176 194 - T 01-11-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MLA2C4_06070 bcc55decefc8cb22fe50dada2b198a1c 319 Gene3D G3DSA:3.40.50.1400 8 302 1.0E-99 T 01-11-2018 MLA2C4_05200 4794852295a277b4f8b8aa8bdd931d0d 70 Pfam PF02734 DAK2 domain 14 56 1.2E-10 T 01-11-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05200 4794852295a277b4f8b8aa8bdd931d0d 70 Gene3D G3DSA:1.25.40.340 5 60 9.1E-11 T 01-11-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_05200 4794852295a277b4f8b8aa8bdd931d0d 70 SUPERFAMILY SSF101473 13 59 3.66E-10 T 01-11-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 MLA2C4_15475 9451d7a299eff424e2714d573e5d31d7 415 SUPERFAMILY SSF52440 174 286 8.63E-12 T 01-11-2018 IPR016185 Pre-ATP-grasp domain superfamily MLA2C4_15475 9451d7a299eff424e2714d573e5d31d7 415 Gene3D G3DSA:3.30.1490.330 271 365 1.9E-11 T 01-11-2018 MLA2C4_15475 9451d7a299eff424e2714d573e5d31d7 415 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 19 413 8.1E-74 T 01-11-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MLA2C4_15475 9451d7a299eff424e2714d573e5d31d7 415 SUPERFAMILY SSF56059 7 411 1.15E-53 T 01-11-2018 MLA2C4_06460 b2098c2ddfb9942f2169cbbd81eefc76 223 Pfam PF14329 Domain of unknown function (DUF4386) 10 217 7.8E-45 T 01-11-2018 IPR025495 Protein of unknown function DUF4386 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 PRINTS PR00207 Flagellin signature 74 93 3.1E-14 T 01-11-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 PRINTS PR00207 Flagellin signature 109 132 3.1E-14 T 01-11-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 PRINTS PR00207 Flagellin signature 35 52 3.1E-14 T 01-11-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 SUPERFAMILY SSF64518 1 265 2.88E-74 T 01-11-2018 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Gene3D G3DSA:2.170.280.10 163 172 1.7E-29 T 01-11-2018 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 5.6E-35 T 01-11-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Gene3D G3DSA:1.20.1330.10 173 224 1.7E-29 T 01-11-2018 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Gene3D G3DSA:1.20.1330.10 43 140 6.5E-45 T 01-11-2018 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Gene3D G3DSA:1.20.58.1830 3 31 6.5E-45 T 01-11-2018 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Gene3D G3DSA:1.20.58.1830 230 264 1.7E-29 T 01-11-2018 MLA2C4_08670 9610e606cc2d0c3a7684ec5c44267db9 266 Pfam PF00700 Bacterial flagellin C-terminal helical region 180 264 2.8E-22 T 01-11-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MLA2C4_24635 15f4984e4ae7c358cd631b736ad115df 140 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 14 93 5.4E-23 T 01-11-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MLA2C4_24635 15f4984e4ae7c358cd631b736ad115df 140 Gene3D G3DSA:1.10.3420.10 57 137 1.8E-37 T 01-11-2018 IPR023292 NTP pyrophosphohydrolase-like domain superfamily MLA2C4_24635 15f4984e4ae7c358cd631b736ad115df 140 Gene3D G3DSA:1.10.3420.10 5 56 9.3E-9 T 01-11-2018 IPR023292 NTP pyrophosphohydrolase-like domain superfamily MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 PIRSF PIRSF036979 10 317 5.2E-61 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 PRINTS PR00116 Arginase signature 123 138 2.4E-10 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 PRINTS PR00116 Arginase signature 238 267 2.4E-10 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 PRINTS PR00116 Arginase signature 273 287 2.4E-10 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 311 1.3E-85 T 01-11-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 Pfam PF00491 Arginase family 37 311 2.0E-71 T 01-11-2018 IPR006035 Ureohydrolase GO:0046872 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 ProSitePatterns PS01053 Arginase family signature. 241 262 - T 01-11-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 SUPERFAMILY SSF52768 29 313 7.38E-75 T 01-11-2018 IPR023696 Ureohydrolase domain superfamily MLA2C4_18960 3c0ac8545dbe2e9279ae52ce3f009952 323 Gene3D G3DSA:3.40.800.10 22 316 2.1E-93 T 01-11-2018 MLA2C4_04490 54ae5c8d5971e08d8aa96dbf1d9567ca 375 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 12 279 7.9E-78 T 01-11-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MLA2C4_04490 54ae5c8d5971e08d8aa96dbf1d9567ca 375 Pfam PF00999 Sodium/hydrogen exchanger family 8 370 4.6E-79 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MLA2C4_04490 54ae5c8d5971e08d8aa96dbf1d9567ca 375 Gene3D G3DSA:1.20.1530.20 2 375 8.0E-106 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_17385 d858873aa1eb9f8a216a66c9a36aadde 338 SUPERFAMILY SSF53474 13 276 4.09E-36 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_17385 d858873aa1eb9f8a216a66c9a36aadde 338 Pfam PF12146 Serine aminopeptidase, S33 55 275 8.4E-19 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_17385 d858873aa1eb9f8a216a66c9a36aadde 338 Gene3D G3DSA:3.40.50.1820 6 320 4.1E-46 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_20645 4e217d23730d44303d023269b7abe8eb 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 94 4.1E-8 T 01-11-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MLA2C4_20645 4e217d23730d44303d023269b7abe8eb 151 SUPERFAMILY SSF50475 6 96 8.49E-10 T 01-11-2018 MLA2C4_20645 4e217d23730d44303d023269b7abe8eb 151 Gene3D G3DSA:2.30.110.10 1 150 7.6E-61 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 MLA2C4_00830 0c957c1783858c755543d63c3e05a5a2 264 Pfam PF02361 Cobalt transport protein 13 235 3.0E-58 T 01-11-2018 IPR003339 ABC/ECF transporter, transmembrane component MLA2C4_00830 0c957c1783858c755543d63c3e05a5a2 264 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 36.821 T 01-11-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 MLA2C4_25040 abe5c53e018e90268af53419f701e6bd 222 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 7 112 3.4E-32 T 01-11-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 MLA2C4_25040 abe5c53e018e90268af53419f701e6bd 222 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 207 1.1E-70 T 01-11-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 MLA2C4_25040 abe5c53e018e90268af53419f701e6bd 222 Gene3D G3DSA:1.10.1760.20 5 211 5.7E-63 T 01-11-2018 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 238 253 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 52 76 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 159 183 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 123 148 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 221 236 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 185 210 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 PRINTS PR00118 Beta-lactamase class A signature 83 100 3.7E-62 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 Gene3D G3DSA:3.40.710.10 39 305 2.6E-77 T 01-11-2018 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 Pfam PF13354 Beta-lactamase enzyme family 73 278 1.6E-36 T 01-11-2018 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 ProSitePatterns PS00146 Beta-lactamase class-A active site. 85 100 - T 01-11-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 MLA2C4_14445 553bbaa6fc6b7700050462631164745d 312 SUPERFAMILY SSF56601 55 306 3.59E-74 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_12160 031e55ad7b2cc7a029245c35480f54cf 385 Pfam PF00149 Calcineurin-like phosphoesterase 1 137 5.5E-13 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_12160 031e55ad7b2cc7a029245c35480f54cf 385 SUPERFAMILY SSF56300 1 318 7.29E-52 T 01-11-2018 MLA2C4_12160 031e55ad7b2cc7a029245c35480f54cf 385 Gene3D G3DSA:3.60.21.10 1 271 2.7E-74 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_12160 031e55ad7b2cc7a029245c35480f54cf 385 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 272 357 3.2E-8 T 01-11-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain MLA2C4_12160 031e55ad7b2cc7a029245c35480f54cf 385 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 249 4.4E-45 T 01-11-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 MLA2C4_14705 3aa3e1ef9b8e557cb285d31b2a25e986 159 SUPERFAMILY SSF109854 27 152 6.23E-23 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_14705 3aa3e1ef9b8e557cb285d31b2a25e986 159 Pfam PF12867 DinB superfamily 26 146 6.8E-10 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_14705 3aa3e1ef9b8e557cb285d31b2a25e986 159 Gene3D G3DSA:1.20.120.450 24 153 6.0E-20 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_08755 b37416b082a44ce02b4ef64ba2fa52f0 103 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 100 3.0E-24 T 01-11-2018 IPR008407 Branched-chain amino acid transport, AzlD MLA2C4_09365 2bced5cc1bb8b7640e744c67720705d9 274 Gene3D G3DSA:3.30.460.10 5 125 4.6E-12 T 01-11-2018 MLA2C4_09365 2bced5cc1bb8b7640e744c67720705d9 274 Pfam PF13228 Domain of unknown function (DUF4037) 115 210 4.4E-13 T 01-11-2018 IPR025117 Domain of unknown function DUF4037 MLA2C4_09365 2bced5cc1bb8b7640e744c67720705d9 274 SUPERFAMILY SSF81301 12 105 3.14E-8 T 01-11-2018 MLA2C4_17930 eb6180b98cc0a56c21da0544cf9f7da6 96 Pfam PF12650 Domain of unknown function (DUF3784) 10 93 5.2E-12 T 01-11-2018 IPR017259 Uncharacterised conserved protein UCP037672 MLA2C4_17930 eb6180b98cc0a56c21da0544cf9f7da6 96 PIRSF PIRSF037672 1 96 6.3E-41 T 01-11-2018 IPR017259 Uncharacterised conserved protein UCP037672 MLA2C4_03925 97016a10ee0dc59ca2d016be012a68ef 249 Gene3D G3DSA:3.40.50.300 1 228 2.8E-58 T 01-11-2018 MLA2C4_03925 97016a10ee0dc59ca2d016be012a68ef 249 SUPERFAMILY SSF52540 6 222 4.28E-57 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03925 97016a10ee0dc59ca2d016be012a68ef 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_03925 97016a10ee0dc59ca2d016be012a68ef 249 SMART SM00382 31 207 4.5E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_03925 97016a10ee0dc59ca2d016be012a68ef 249 Pfam PF00005 ABC transporter 23 157 2.3E-26 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03285 358d5467ea4eded04ef777964528f0f6 297 Gene3D G3DSA:3.40.50.300 41 212 8.2E-33 T 01-11-2018 MLA2C4_03285 358d5467ea4eded04ef777964528f0f6 297 Pfam PF07728 AAA domain (dynein-related subfamily) 58 195 3.0E-26 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MLA2C4_03285 358d5467ea4eded04ef777964528f0f6 297 SUPERFAMILY SSF52540 46 272 7.71E-32 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03285 358d5467ea4eded04ef777964528f0f6 297 SMART SM00382 55 201 1.5E-4 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_05775 b76c0e709a4e2aa9eb91e792122fd19c 166 SUPERFAMILY SSF109854 2 157 1.14E-24 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_05775 b76c0e709a4e2aa9eb91e792122fd19c 166 Gene3D G3DSA:1.20.120.450 1 164 3.0E-18 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_05775 b76c0e709a4e2aa9eb91e792122fd19c 166 Pfam PF12867 DinB superfamily 11 157 2.5E-11 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_06635 c85d9823137518d00fa65cf552be8ffb 291 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 90 1.5E-25 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_06635 c85d9823137518d00fa65cf552be8ffb 291 Pfam PF06013 Proteins of 100 residues with WXG 4 88 2.0E-21 T 01-11-2018 IPR010310 Type VII secretion system ESAT-6-like MLA2C4_06635 c85d9823137518d00fa65cf552be8ffb 291 SUPERFAMILY SSF140453 3 90 3.79E-19 T 01-11-2018 IPR036689 ESAT-6-like superfamily MLA2C4_06635 c85d9823137518d00fa65cf552be8ffb 291 Gene3D G3DSA:1.10.287.850 2 95 5.9E-26 T 01-11-2018 MLA2C4_25090 9f73aec470e614761e7b486d5946f3ae 315 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 244 1.6E-63 T 01-11-2018 MLA2C4_25090 9f73aec470e614761e7b486d5946f3ae 315 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 11 311 4.8E-68 T 01-11-2018 IPR010106 Recombination-promoting nuclease RpnA MLA2C4_05135 b2bc7de8b0096e373e9ec64397ef8d27 391 SUPERFAMILY SSF103473 3 377 4.05E-47 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_05135 b2bc7de8b0096e373e9ec64397ef8d27 391 Gene3D G3DSA:1.20.1250.20 5 379 3.4E-39 T 01-11-2018 MLA2C4_05135 b2bc7de8b0096e373e9ec64397ef8d27 391 Pfam PF07690 Major Facilitator Superfamily 12 314 2.9E-28 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_14560 a2ee7c5acb453243e057ebaa1926c1f4 178 Gene3D G3DSA:3.30.70.1280 1 88 3.3E-31 T 01-11-2018 MLA2C4_14560 a2ee7c5acb453243e057ebaa1926c1f4 178 SUPERFAMILY SSF160379 1 175 8.63E-52 T 01-11-2018 MLA2C4_14560 a2ee7c5acb453243e057ebaa1926c1f4 178 Pfam PF08002 Protein of unknown function (DUF1697) 1 137 1.8E-43 T 01-11-2018 IPR012545 Protein of unknown function DUF1697 MLA2C4_14560 a2ee7c5acb453243e057ebaa1926c1f4 178 PIRSF PIRSF008502 1 178 7.6E-65 T 01-11-2018 IPR012545 Protein of unknown function DUF1697 MLA2C4_13690 173ad40e5c403c48a4e0af0f9804e0c4 287 Gene3D G3DSA:1.10.510.10 72 286 8.9E-15 T 01-11-2018 MLA2C4_13690 173ad40e5c403c48a4e0af0f9804e0c4 287 SUPERFAMILY SSF56112 38 284 3.07E-16 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_08415 7d7f30ff6a3c9ab75bcd5ebb25bfcc7d 387 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 281 1.9E-78 T 01-11-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MLA2C4_08415 7d7f30ff6a3c9ab75bcd5ebb25bfcc7d 387 Gene3D G3DSA:1.20.1530.20 2 386 7.9E-107 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_08415 7d7f30ff6a3c9ab75bcd5ebb25bfcc7d 387 Pfam PF00999 Sodium/hydrogen exchanger family 10 373 4.8E-76 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MLA2C4_08035 19116bd6d7883ec87725fee3f9b6cb92 227 Pfam PF04298 Putative neutral zinc metallopeptidase 4 219 9.3E-94 T 01-11-2018 IPR007395 Putative neutral zinc metallopeptidase MLA2C4_02770 9c2ee1969b1a4c0ccee2d6d6f7d6467d 261 Pfam PF06182 ABC-2 family transporter protein 34 260 7.9E-53 T 01-11-2018 IPR010390 Protein of unknown function DUF990 MLA2C4_13325 cdc86979dc2b29092336b740e6a20bbb 206 SUPERFAMILY SSF52266 11 199 9.01E-34 T 01-11-2018 MLA2C4_13325 cdc86979dc2b29092336b740e6a20bbb 206 Gene3D G3DSA:3.40.50.1110 7 199 1.5E-30 T 01-11-2018 IPR036514 SGNH hydrolase superfamily MLA2C4_13325 cdc86979dc2b29092336b740e6a20bbb 206 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 17 188 2.4E-23 T 01-11-2018 IPR013830 SGNH hydrolase-type esterase domain MLA2C4_02685 22a5bf9071f4f5e2e31ad4ce054db2ec 105 Pfam PF08838 Protein of unknown function (DUF1811) 5 103 7.2E-39 T 01-11-2018 IPR014938 Protein of unknown function DUF1811 MLA2C4_02685 22a5bf9071f4f5e2e31ad4ce054db2ec 105 Gene3D G3DSA:1.10.287.880 1 52 2.9E-25 T 01-11-2018 MLA2C4_02685 22a5bf9071f4f5e2e31ad4ce054db2ec 105 SUPERFAMILY SSF101697 3 105 7.98E-45 T 01-11-2018 IPR036289 Hypothetical protein YfhH MLA2C4_02685 22a5bf9071f4f5e2e31ad4ce054db2ec 105 Gene3D G3DSA:2.30.30.340 54 105 1.4E-19 T 01-11-2018 MLA2C4_01210 7fb4b33b5a5d9e1adecf0bf3d78cee87 109 Pfam PF14470 Bacterial PH domain 13 104 1.0E-13 T 01-11-2018 IPR039519 YokE-like, PH domain MLA2C4_12655 e84faa8eb6f7be77e6ac2d1238fa3c05 70 Pfam PF01381 Helix-turn-helix 7 61 3.5E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12655 e84faa8eb6f7be77e6ac2d1238fa3c05 70 SMART SM00530 6 61 3.1E-16 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_12655 e84faa8eb6f7be77e6ac2d1238fa3c05 70 Gene3D G3DSA:1.10.260.40 2 66 1.6E-26 T 01-11-2018 MLA2C4_12655 e84faa8eb6f7be77e6ac2d1238fa3c05 70 SUPERFAMILY SSF47413 2 67 4.83E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_26045 353bd60928725b129a02978035873347 48 Pfam PF14115 YuzL-like protein 3 42 1.7E-17 T 01-11-2018 IPR025625 YuzL-like protein MLA2C4_24355 046af072ec7a8b900d49fefc721d1958 182 SUPERFAMILY SSF55729 6 174 9.47E-40 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_24355 046af072ec7a8b900d49fefc721d1958 182 Pfam PF13302 Acetyltransferase (GNAT) domain 11 150 9.7E-22 T 01-11-2018 IPR000182 GNAT domain MLA2C4_24355 046af072ec7a8b900d49fefc721d1958 182 Gene3D G3DSA:3.40.630.30 2 176 6.8E-45 T 01-11-2018 MLA2C4_02280 dcd721435983f69d448ff24a1f533349 219 SUPERFAMILY SSF51391 9 214 2.09E-68 T 01-11-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02280 dcd721435983f69d448ff24a1f533349 219 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 13 216 28.56 T 01-11-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02280 dcd721435983f69d448ff24a1f533349 219 Gene3D G3DSA:3.20.20.70 1 218 8.5E-77 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_02280 dcd721435983f69d448ff24a1f533349 219 Pfam PF02581 Thiamine monophosphate synthase 15 198 2.2E-63 T 01-11-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_02280 dcd721435983f69d448ff24a1f533349 219 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 14 211 7.6E-67 T 01-11-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MLA2C4_15040 62ef0bfd03b5e67b7259d3ada750e7bd 201 Pfam PF09335 SNARE associated Golgi protein 30 156 1.7E-25 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_18320 99ed6af3bdad328ee0be34b63d9e11f1 389 Gene3D G3DSA:3.40.50.720 103 367 5.4E-66 T 01-11-2018 MLA2C4_18320 99ed6af3bdad328ee0be34b63d9e11f1 389 Pfam PF00899 ThiF family 121 351 7.8E-51 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MLA2C4_18320 99ed6af3bdad328ee0be34b63d9e11f1 389 SUPERFAMILY SSF69572 95 366 3.53E-59 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_14405 85ebd6b2d2191e6f72caa12d49e37acc 371 SUPERFAMILY SSF51905 2 366 1.42E-43 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_14405 85ebd6b2d2191e6f72caa12d49e37acc 371 Pfam PF01266 FAD dependent oxidoreductase 4 351 1.2E-56 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_14405 85ebd6b2d2191e6f72caa12d49e37acc 371 SUPERFAMILY SSF54373 224 311 7.19E-16 T 01-11-2018 MLA2C4_14405 85ebd6b2d2191e6f72caa12d49e37acc 371 Gene3D G3DSA:3.30.9.10 88 311 2.8E-84 T 01-11-2018 MLA2C4_14405 85ebd6b2d2191e6f72caa12d49e37acc 371 Gene3D G3DSA:3.50.50.60 5 351 2.8E-84 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_03200 4084f7c56bd05226d2341f4fac07267d 392 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 3.9E-58 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_03200 4084f7c56bd05226d2341f4fac07267d 392 Pfam PF07670 Nucleoside recognition 91 188 1.5E-5 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_03200 4084f7c56bd05226d2341f4fac07267d 392 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.6E-20 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_07670 9a4569115a35dc918102eed7cdf4d972 206 SUPERFAMILY SSF109755 7 197 3.66E-6 T 01-11-2018 MLA2C4_07670 9a4569115a35dc918102eed7cdf4d972 206 Pfam PF01865 Protein of unknown function DUF47 5 203 6.9E-27 T 01-11-2018 IPR018445 Putative phosphate transport regulator MLA2C4_07670 9a4569115a35dc918102eed7cdf4d972 206 Gene3D G3DSA:1.20.58.220 10 206 2.0E-57 T 01-11-2018 IPR038078 PhoU-like domain superfamily MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 169 2.2E-34 T 01-11-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 9 86 6.2E-10 T 01-11-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 SUPERFAMILY SSF53155 9 86 3.73E-13 T 01-11-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 01-11-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 170 5.4E-30 T 01-11-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 SUPERFAMILY SSF46767 89 170 1.44E-30 T 01-11-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MLA2C4_19540 8cd0c8f5601e45d8e27431ad44c64cba 176 Gene3D G3DSA:1.10.10.10 89 174 7.9E-34 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_16635 637867eb5107a004baecd12095c19668 405 SUPERFAMILY SSF51905 28 323 3.33E-32 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_16635 637867eb5107a004baecd12095c19668 405 Gene3D G3DSA:3.50.50.60 31 388 8.2E-57 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_16635 637867eb5107a004baecd12095c19668 405 Pfam PF01266 FAD dependent oxidoreductase 30 383 3.1E-44 T 01-11-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MLA2C4_16635 637867eb5107a004baecd12095c19668 405 Gene3D G3DSA:3.30.9.10 123 344 8.2E-57 T 01-11-2018 MLA2C4_23720 83036ae882bb2f58446e3ca6567cb0b6 237 Pfam PF02517 CAAX protease self-immunity 145 232 8.6E-21 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_10325 f39cf4b04403903031f5d308c034ea8e 337 Pfam PF10947 Protein of unknown function (DUF2628) 56 150 2.9E-23 T 01-11-2018 IPR024399 Protein of unknown function DUF2628 MLA2C4_00115 c532f1917109b72306c03424eb57d80c 166 Pfam PF14437 MafB19-like deaminase 6 151 6.7E-42 T 01-11-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MLA2C4_00115 c532f1917109b72306c03424eb57d80c 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 01-11-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MLA2C4_00115 c532f1917109b72306c03424eb57d80c 166 SUPERFAMILY SSF53927 3 155 1.22E-55 T 01-11-2018 IPR016193 Cytidine deaminase-like GO:0003824 MLA2C4_00115 c532f1917109b72306c03424eb57d80c 166 Gene3D G3DSA:3.40.140.10 1 166 1.0E-62 T 01-11-2018 MLA2C4_00115 c532f1917109b72306c03424eb57d80c 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 151 46.549 T 01-11-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MLA2C4_25215 ac143ef32c66890477fed4efaba477f3 251 Gene3D G3DSA:3.20.20.70 1 251 2.4E-115 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_25215 ac143ef32c66890477fed4efaba477f3 251 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 9 245 7.5E-118 T 01-11-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MLA2C4_25215 ac143ef32c66890477fed4efaba477f3 251 Pfam PF07071 KDGP aldolase 9 227 2.5E-105 T 01-11-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MLA2C4_13695 77025c11026f2e9f83883decb06bb58e 250 SUPERFAMILY SSF53335 39 207 5.38E-22 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_13695 77025c11026f2e9f83883decb06bb58e 250 Gene3D G3DSA:3.40.50.150 22 229 8.3E-19 T 01-11-2018 MLA2C4_13695 77025c11026f2e9f83883decb06bb58e 250 Pfam PF13649 Methyltransferase domain 50 132 2.2E-12 T 01-11-2018 MLA2C4_08230 d69e302d7c602e9d3e0f5ecdb26a414e 197 SUPERFAMILY SSF53271 1 189 3.36E-47 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_08230 d69e302d7c602e9d3e0f5ecdb26a414e 197 Pfam PF00156 Phosphoribosyl transferase domain 34 156 4.9E-10 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_08230 d69e302d7c602e9d3e0f5ecdb26a414e 197 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 42.874 T 01-11-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 MLA2C4_08230 d69e302d7c602e9d3e0f5ecdb26a414e 197 Gene3D G3DSA:3.40.50.2020 3 188 2.7E-54 T 01-11-2018 MLA2C4_08230 d69e302d7c602e9d3e0f5ecdb26a414e 197 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 190 9.3E-86 T 01-11-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 MLA2C4_07895 06552f5d6be80161a8fd9238d8643239 44 Pfam PF14140 YpzI-like protein 1 42 7.4E-27 T 01-11-2018 IPR025414 YpzI-like protein MLA2C4_26890 d2f5b09fb7c301ba55121212df473226 375 Gene3D G3DSA:1.10.260.150 66 330 6.1E-94 T 01-11-2018 MLA2C4_26890 d2f5b09fb7c301ba55121212df473226 375 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 239 3.8E-52 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_26890 d2f5b09fb7c301ba55121212df473226 375 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 239 5.0E-51 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_03570 ebc3697f9259f16e6fae463c6f7ee58d 333 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 40 288 2.3E-15 T 01-11-2018 IPR005135 Endonuclease/exonuclease/phosphatase MLA2C4_03570 ebc3697f9259f16e6fae463c6f7ee58d 333 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 37 330 3.5E-146 T 01-11-2018 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 MLA2C4_03570 ebc3697f9259f16e6fae463c6f7ee58d 333 SUPERFAMILY SSF56219 34 330 1.96E-80 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_03570 ebc3697f9259f16e6fae463c6f7ee58d 333 Gene3D G3DSA:3.60.10.10 28 333 5.0E-101 T 01-11-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MLA2C4_22475 866c6d5832d2d9b85f0fcc2a9dfcc105 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 24.83 T 01-11-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MLA2C4_22475 866c6d5832d2d9b85f0fcc2a9dfcc105 156 Pfam PF02130 Uncharacterized protein family UPF0054 14 151 1.6E-50 T 01-11-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MLA2C4_22475 866c6d5832d2d9b85f0fcc2a9dfcc105 156 Gene3D G3DSA:3.40.390.30 4 156 7.1E-47 T 01-11-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 MLA2C4_22475 866c6d5832d2d9b85f0fcc2a9dfcc105 156 SUPERFAMILY SSF55486 2 155 8.06E-47 T 01-11-2018 MLA2C4_22475 866c6d5832d2d9b85f0fcc2a9dfcc105 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 152 1.2E-43 T 01-11-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MLA2C4_22475 866c6d5832d2d9b85f0fcc2a9dfcc105 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 01-11-2018 IPR020549 Endoribonuclease YbeY, conserved site MLA2C4_09105 a57c682374148be93ef98698c1cd21c8 312 Gene3D G3DSA:3.40.50.1820 2 207 8.9E-31 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09105 a57c682374148be93ef98698c1cd21c8 312 Pfam PF02450 Lecithin:cholesterol acyltransferase 37 139 3.4E-12 T 01-11-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 MLA2C4_09105 a57c682374148be93ef98698c1cd21c8 312 SUPERFAMILY SSF53474 3 158 1.96E-18 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_06440 78c00c5b255ac6b575d87af3d9f718db 172 SUPERFAMILY SSF55144 1 169 2.96E-33 T 01-11-2018 IPR009097 Cyclic phosphodiesterase MLA2C4_06440 78c00c5b255ac6b575d87af3d9f718db 172 Pfam PF13563 2'-5' RNA ligase superfamily 13 153 1.0E-25 T 01-11-2018 MLA2C4_06440 78c00c5b255ac6b575d87af3d9f718db 172 Hamap MF_01444 Putative phosphoesterase . 1 168 39.263 T 01-11-2018 IPR022932 Putative phosphoesterase YjcG MLA2C4_06440 78c00c5b255ac6b575d87af3d9f718db 172 Gene3D G3DSA:3.90.1140.10 2 171 2.4E-45 T 01-11-2018 MLA2C4_24705 2ad4c7b5869640968cc156ea860ebcec 190 Gene3D G3DSA:3.40.50.150 1 190 3.9E-70 T 01-11-2018 MLA2C4_24705 2ad4c7b5869640968cc156ea860ebcec 190 SUPERFAMILY SSF53335 12 163 2.76E-22 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_24705 2ad4c7b5869640968cc156ea860ebcec 190 Pfam PF06962 Putative rRNA methylase 48 188 1.1E-50 T 01-11-2018 IPR010719 Putative rRNA methylase MLA2C4_26010 025504a149e01bd34dad07bc1b139fbe 82 Pfam PF07875 Coat F domain 2 63 3.0E-18 T 01-11-2018 IPR012851 Spore coat protein CotF-like MLA2C4_10760 18f4b33fa831fd2683e4548dea24928f 226 Gene3D G3DSA:1.10.3950.10 69 226 3.3E-68 T 01-11-2018 IPR038267 Putative ECF-type sigma factor negative effector MLA2C4_10760 18f4b33fa831fd2683e4548dea24928f 226 Pfam PF12207 Domain of unknown function (DUF3600) 65 224 3.8E-78 T 01-11-2018 IPR022019 Domain of unknown function DUF3600 MLA2C4_25015 7e3ddc2ee53babcd2eb58a92cfd6fb51 221 Pfam PF04012 PspA/IM30 family 2 218 8.1E-48 T 01-11-2018 IPR007157 PspA/IM30 MLA2C4_12750 6034e30e00085c4919aa677dafdaad24 427 PIRSF PIRSF006351 1 425 3.2E-148 T 01-11-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_12750 6034e30e00085c4919aa677dafdaad24 427 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 418 6.0E-120 T 01-11-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 MLA2C4_12750 6034e30e00085c4919aa677dafdaad24 427 Pfam PF02378 Phosphotransferase system, EIIC 29 344 3.3E-56 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_14595 a3ba546c972c59ac5b8a5a020eee659a 110 Pfam PF13028 Protein of unknown function (DUF3889) 19 106 1.7E-30 T 01-11-2018 IPR024987 Protein of unknown function DUF3889 MLA2C4_14595 a3ba546c972c59ac5b8a5a020eee659a 110 Gene3D G3DSA:3.10.450.390 23 109 1.1E-30 T 01-11-2018 MLA2C4_05325 b1cd992ed3a5b949a722a2ca8572613f 146 Pfam PF00210 Ferritin-like domain 9 140 7.9E-26 T 01-11-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MLA2C4_05325 b1cd992ed3a5b949a722a2ca8572613f 146 Gene3D G3DSA:1.20.1260.10 1 146 6.6E-53 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_05325 b1cd992ed3a5b949a722a2ca8572613f 146 SUPERFAMILY SSF47240 6 140 4.36E-29 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_14290 2dfcc6d9ca85512cf475a736cd92f327 170 SUPERFAMILY SSF55811 5 124 1.3E-20 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_14290 2dfcc6d9ca85512cf475a736cd92f327 170 Gene3D G3DSA:3.90.79.10 2 159 3.3E-24 T 01-11-2018 MLA2C4_14290 2dfcc6d9ca85512cf475a736cd92f327 170 Pfam PF00293 NUDIX domain 7 76 1.2E-12 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_08885 dcc984dfc2543fb40eacd4d39143ada7 363 Gene3D G3DSA:3.40.710.10 35 351 5.9E-39 T 01-11-2018 MLA2C4_08885 dcc984dfc2543fb40eacd4d39143ada7 363 Pfam PF13354 Beta-lactamase enzyme family 57 286 1.3E-17 T 01-11-2018 MLA2C4_08885 dcc984dfc2543fb40eacd4d39143ada7 363 SUPERFAMILY SSF56601 12 353 1.11E-27 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_06030 6a4acd852a2db4a0638b091ec3de2770 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.4E-28 T 01-11-2018 IPR019618 Spore germination protein GerPA/GerPF MLA2C4_12365 e71d87d8f08c5dc8a98b8a558d1faf7a 156 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 1.4E-24 T 01-11-2018 IPR006750 Putative inner membrane exporter, YdcZ MLA2C4_19785 715ac7aaf64fa8995af68ba082bbb0ce 303 Pfam PF13413 Helix-turn-helix domain 8 68 2.5E-20 T 01-11-2018 MLA2C4_19785 715ac7aaf64fa8995af68ba082bbb0ce 303 Pfam PF13464 Domain of unknown function (DUF4115) 217 278 3.6E-9 T 01-11-2018 IPR025194 Domain of unknown function DUF4115 MLA2C4_19785 715ac7aaf64fa8995af68ba082bbb0ce 303 SUPERFAMILY SSF47413 3 73 1.72E-5 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_19785 715ac7aaf64fa8995af68ba082bbb0ce 303 Gene3D G3DSA:1.10.260.40 1 104 5.9E-28 T 01-11-2018 MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 415 4.9E-127 T 01-11-2018 MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 ProSitePatterns PS00942 glpT family of transporters signature. 150 166 - T 01-11-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 Gene3D G3DSA:1.20.1250.20 19 226 5.9E-50 T 01-11-2018 MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 SUPERFAMILY SSF103473 14 436 2.35E-79 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 Gene3D G3DSA:1.20.1250.20 241 440 1.9E-48 T 01-11-2018 MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 Pfam PF07690 Major Facilitator Superfamily 35 397 1.4E-48 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_27185 72eb51fb628f9e4a46274416651b3d01 444 PIRSF PIRSF002808 6 444 1.2E-125 T 01-11-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 MLA2C4_09800 ad3a19e375ca8479d8edb5545af5448c 331 SUPERFAMILY SSF53901 26 331 4.27E-31 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_09800 ad3a19e375ca8479d8edb5545af5448c 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 186 1.7E-15 T 01-11-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_09800 ad3a19e375ca8479d8edb5545af5448c 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 243 331 5.6E-23 T 01-11-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MLA2C4_09800 ad3a19e375ca8479d8edb5545af5448c 331 Gene3D G3DSA:3.40.47.10 3 331 2.1E-72 T 01-11-2018 IPR016039 Thiolase-like GO:0003824 MLA2C4_22610 957ad7eb28ac83e16ac88c86d4fcec16 118 SUPERFAMILY SSF81301 2 114 1.42E-39 T 01-11-2018 MLA2C4_22610 957ad7eb28ac83e16ac88c86d4fcec16 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 24.585 T 01-11-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MLA2C4_22610 957ad7eb28ac83e16ac88c86d4fcec16 118 Gene3D G3DSA:3.30.460.10 1 108 7.5E-38 T 01-11-2018 MLA2C4_22610 957ad7eb28ac83e16ac88c86d4fcec16 118 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 4.6E-26 T 01-11-2018 MLA2C4_22610 957ad7eb28ac83e16ac88c86d4fcec16 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 104 3.1E-36 T 01-11-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MLA2C4_15855 f31bdf78dbeafb3412991961c7dbc416 178 Pfam PF11193 Protein of unknown function (DUF2812) 15 124 1.7E-25 T 01-11-2018 IPR021359 Protein of unknown function DUF2812 MLA2C4_09170 e0c68f0d019d8c1463068ee9df61ff4f 44 Pfam PF13070 Protein of unknown function (DUF3934) 1 42 2.6E-21 T 01-11-2018 IPR025175 Protein of unknown function DUF3934 MLA2C4_08350 8f4fe31620a5d5bd56203d744ef2f5c0 162 Pfam PF06177 QueT transporter 7 153 5.6E-31 T 01-11-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 MLA2C4_08350 8f4fe31620a5d5bd56203d744ef2f5c0 162 PIRSF PIRSF031501 1 161 1.8E-54 T 01-11-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 MLA2C4_15685 b033e51c716e2419fa57460c62ac4b55 120 Gene3D G3DSA:2.60.120.10 3 119 4.0E-22 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_15685 b033e51c716e2419fa57460c62ac4b55 120 SUPERFAMILY SSF51182 23 103 7.58E-24 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_15685 b033e51c716e2419fa57460c62ac4b55 120 Pfam PF07883 Cupin domain 30 99 3.5E-19 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_02920 a992263ac70eb2ea86cd73009b3542af 385 Pfam PF07282 Putative transposase DNA-binding domain 309 377 6.8E-21 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_02920 a992263ac70eb2ea86cd73009b3542af 385 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 263 336 1.4E-10 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_02920 a992263ac70eb2ea86cd73009b3542af 385 Pfam PF12323 Helix-turn-helix domain 1 46 1.2E-17 T 01-11-2018 IPR021027 Transposase, putative, helix-turn-helix domain MLA2C4_02920 a992263ac70eb2ea86cd73009b3542af 385 Pfam PF01385 Probable transposase 176 296 1.6E-12 T 01-11-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MLA2C4_03770 c8ca84941c6f0da4d9544e2b4f29474b 306 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 286 7.6E-82 T 01-11-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MLA2C4_03770 c8ca84941c6f0da4d9544e2b4f29474b 306 SUPERFAMILY SSF161098 16 275 8.18E-40 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03770 c8ca84941c6f0da4d9544e2b4f29474b 306 Gene3D G3DSA:1.10.3720.10 2 280 1.5E-31 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03770 c8ca84941c6f0da4d9544e2b4f29474b 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 291 3.1E-36 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_09840 2cd8f8e21d8e7ec53d7a5cfd489f85ed 182 Pfam PF16157 Domain of unknown function (DUF4865) 1 181 1.9E-68 T 01-11-2018 IPR032349 Protein of unknown function DUF4865 MLA2C4_03175 6ef545f055073295bbcd949511581604 182 Pfam PF09335 SNARE associated Golgi protein 33 149 3.2E-19 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_03685 f78adaa2aa53957cfa8f06305f063165 103 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 22 92 3.0E-13 T 01-11-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MLA2C4_03685 f78adaa2aa53957cfa8f06305f063165 103 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 13 103 1.9E-38 T 01-11-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 MLA2C4_22025 a3662007f5b51c3ff848cc04e90a2f94 127 Gene3D G3DSA:3.40.250.10 32 127 1.8E-28 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_22025 a3662007f5b51c3ff848cc04e90a2f94 127 SMART SM00450 31 126 7.9E-26 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_22025 a3662007f5b51c3ff848cc04e90a2f94 127 SUPERFAMILY SSF52821 11 121 1.7E-33 T 01-11-2018 IPR036873 Rhodanese-like domain superfamily MLA2C4_22025 a3662007f5b51c3ff848cc04e90a2f94 127 Pfam PF00581 Rhodanese-like domain 43 121 7.4E-18 T 01-11-2018 IPR001763 Rhodanese-like domain MLA2C4_15500 933c626be2b84878595436dfd42f7be6 166 SUPERFAMILY SSF55729 1 164 4.56E-30 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_15500 933c626be2b84878595436dfd42f7be6 166 Pfam PF13420 Acetyltransferase (GNAT) domain 2 158 3.9E-21 T 01-11-2018 MLA2C4_15500 933c626be2b84878595436dfd42f7be6 166 Gene3D G3DSA:3.40.630.30 1 165 1.7E-44 T 01-11-2018 MLA2C4_02935 6bb85c0f74240959c688fa40aba83949 295 Pfam PF12671 Putative amidase domain 136 289 1.2E-36 T 01-11-2018 IPR024301 Putative amidase domain MLA2C4_14930 f52de41a623e41ae50171a58f44fb026 65 Pfam PF13209 Protein of unknown function (DUF4017) 1 60 4.9E-37 T 01-11-2018 IPR025090 Protein of unknown function DUF4017 MLA2C4_02510 0ae38b31ac4960fca862a6a3f04065bb 351 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 7 348 8.0E-119 T 01-11-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_02510 0ae38b31ac4960fca862a6a3f04065bb 351 TIGRFAM TIGR00378 cax: calcium/proton exchanger 11 349 2.1E-143 T 01-11-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 MLA2C4_02510 0ae38b31ac4960fca862a6a3f04065bb 351 Pfam PF01699 Sodium/calcium exchanger protein 28 179 2.1E-19 T 01-11-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MLA2C4_02510 0ae38b31ac4960fca862a6a3f04065bb 351 Pfam PF01699 Sodium/calcium exchanger protein 206 343 2.3E-19 T 01-11-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MLA2C4_02510 0ae38b31ac4960fca862a6a3f04065bb 351 Gene3D G3DSA:1.20.1420.30 58 342 1.4E-23 T 01-11-2018 MLA2C4_02510 0ae38b31ac4960fca862a6a3f04065bb 351 Gene3D G3DSA:1.20.58.1130 196 238 1.4E-23 T 01-11-2018 MLA2C4_13950 4e8e81a3feaca8fda66bf096c6d57385 142 SUPERFAMILY SSF160631 12 133 9.55E-12 T 01-11-2018 MLA2C4_13950 4e8e81a3feaca8fda66bf096c6d57385 142 Gene3D G3DSA:3.40.1580.10 5 138 7.3E-24 T 01-11-2018 IPR037883 Knr4/Smi1-like domain superfamily MLA2C4_13950 4e8e81a3feaca8fda66bf096c6d57385 142 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 19 131 8.4E-6 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_07360 7a95ba62d5586005c3e750aa18d36400 155 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 50 147 1.6E-25 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_07360 7a95ba62d5586005c3e750aa18d36400 155 PIRSF PIRSF021377 20 155 2.0E-47 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_07360 7a95ba62d5586005c3e750aa18d36400 155 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 22 151 7.4E-47 T 01-11-2018 IPR014229 Sporulation protein YtfJ MLA2C4_04480 a8cb6ee48c1bd5a891f2592606993f82 467 Gene3D G3DSA:1.20.1740.10 17 465 1.0E-137 T 01-11-2018 MLA2C4_04480 a8cb6ee48c1bd5a891f2592606993f82 467 PIRSF PIRSF006060 6 467 2.6E-102 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_04480 a8cb6ee48c1bd5a891f2592606993f82 467 Pfam PF13520 Amino acid permease 24 440 4.2E-63 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 Pfam PF07690 Major Facilitator Superfamily 215 388 2.8E-19 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 Pfam PF07690 Major Facilitator Superfamily 18 199 2.6E-43 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 SUPERFAMILY SSF103473 15 395 3.4E-77 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 Gene3D G3DSA:1.20.1250.20 12 205 7.7E-41 T 01-11-2018 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 PRINTS PR01035 Tetracycline resistance protein signature 339 361 5.5E-5 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 PRINTS PR01035 Tetracycline resistance protein signature 220 236 5.5E-5 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_16230 7ca8c9e4a8877be2ea9790b51ff36c7b 400 Gene3D G3DSA:1.20.1250.20 206 399 7.4E-28 T 01-11-2018 MLA2C4_18720 34152ced9af825b92f173b32622cb7fa 96 PIRSF PIRSF034852 1 96 3.3E-40 T 01-11-2018 IPR008326 Uncharacterised conserved protein UCP034852 MLA2C4_18720 34152ced9af825b92f173b32622cb7fa 96 SUPERFAMILY SSF89360 1 79 2.22E-11 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MLA2C4_18720 34152ced9af825b92f173b32622cb7fa 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 85 1.1E-7 T 01-11-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 207 4.3E-31 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 Gene3D G3DSA:3.40.50.1240 1 238 1.2E-83 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 PIRSF PIRSF000709 172 230 0.2 T 01-11-2018 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 PIRSF PIRSF000709 3 114 1.5E-7 T 01-11-2018 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 44.681 T 01-11-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 SMART SM00855 3 189 9.6E-27 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 01-11-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 234 5.8E-107 T 01-11-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MLA2C4_13270 ff5d34127015607450a7fc34d201818a 245 SUPERFAMILY SSF53254 1 230 1.01E-73 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_07095 bc0fce07ed82f12d0c268b81179b3ef2 177 Pfam PF12867 DinB superfamily 17 166 1.1E-15 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_07095 bc0fce07ed82f12d0c268b81179b3ef2 177 SUPERFAMILY SSF109854 3 173 2.75E-27 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_07095 bc0fce07ed82f12d0c268b81179b3ef2 177 Gene3D G3DSA:1.20.120.450 3 173 1.4E-35 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_15090 6aa3fd30f7ab1e80a1758143f9906b8f 118 Pfam PF04977 Septum formation initiator 41 117 1.0E-17 T 01-11-2018 IPR007060 Septum formation initiator FtsL/DivIC MLA2C4_15295 d05119c086f2a11a0105fd5f1fb02c56 62 Pfam PF13113 Protein of unknown function (DUF3970) 1 56 4.6E-22 T 01-11-2018 IPR025088 Protein of unknown function DUF3970 MLA2C4_23175 e24cd6fa38b0405f3849202be8d8e2f7 462 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 398 3.2E-107 T 01-11-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MLA2C4_23175 e24cd6fa38b0405f3849202be8d8e2f7 462 Pfam PF10150 Ribonuclease E/G family 106 364 3.2E-83 T 01-11-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MLA2C4_23175 e24cd6fa38b0405f3849202be8d8e2f7 462 Gene3D G3DSA:2.40.50.140 30 109 3.6E-21 T 01-11-2018 MLA2C4_23175 e24cd6fa38b0405f3849202be8d8e2f7 462 SUPERFAMILY SSF50249 38 106 5.14E-12 T 01-11-2018 IPR012340 Nucleic acid-binding, OB-fold MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 130 155 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 59 83 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 90 107 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 166 190 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 228 243 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 192 217 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 PRINTS PR00118 Beta-lactamase class A signature 245 260 1.5E-63 T 01-11-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 Pfam PF13354 Beta-lactamase enzyme family 80 285 9.8E-36 T 01-11-2018 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 SUPERFAMILY SSF56601 58 312 1.33E-71 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 ProSitePatterns PS00146 Beta-lactamase class-A active site. 92 107 - T 01-11-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 MLA2C4_04900 2021ad0ebb380c11aedc001d86ea214a 316 Gene3D G3DSA:3.40.710.10 44 312 2.7E-78 T 01-11-2018 MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 123 3.7E-46 T 01-11-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 125 4.9E-50 T 01-11-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 Gene3D G3DSA:1.10.1200.120 1 126 1.4E-41 T 01-11-2018 IPR036019 Gated mechanosensitive channel MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 01-11-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 SUPERFAMILY SSF81330 10 119 8.89E-35 T 01-11-2018 IPR036019 Gated mechanosensitive channel MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.0E-11 T 01-11-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.0E-11 T 01-11-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.0E-11 T 01-11-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MLA2C4_24280 5f904c1d6d4b793a9a1c930cfeed20c7 132 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 124 23.534 T 01-11-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 Gene3D G3DSA:3.40.50.1470 10 207 1.3E-73 T 01-11-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 35 48 - T 01-11-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 Pfam PF01195 Peptidyl-tRNA hydrolase 24 206 4.9E-61 T 01-11-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 SUPERFAMILY SSF53178 21 206 6.41E-73 T 01-11-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 128 138 - T 01-11-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 22 207 4.8E-72 T 01-11-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MLA2C4_00290 b897533c4951be682fde63fd338147b5 207 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 22 199 38.529 T 01-11-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MLA2C4_17695 f20d3252b3750bceff827224c3c4e864 294 SUPERFAMILY SSF103481 190 291 3.79E-16 T 01-11-2018 MLA2C4_17695 f20d3252b3750bceff827224c3c4e864 294 SUPERFAMILY SSF103481 40 145 3.14E-15 T 01-11-2018 MLA2C4_17695 f20d3252b3750bceff827224c3c4e864 294 Pfam PF00892 EamA-like transporter family 6 143 4.5E-26 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_17695 f20d3252b3750bceff827224c3c4e864 294 Pfam PF00892 EamA-like transporter family 154 290 7.5E-21 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_19620 10650d233c190cb807378d9f43bde9e3 223 Pfam PF04172 LrgB-like family 7 217 9.5E-62 T 01-11-2018 IPR007300 CidB/LrgB family MLA2C4_13080 d2b3c59a7680740fb41b70edd95624a8 1541 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 30 353 2.4E-86 T 01-11-2018 IPR007119 Phage minor structural protein, N-terminal domain MLA2C4_13080 d2b3c59a7680740fb41b70edd95624a8 1541 Pfam PF13884 Chaperone of endosialidase 1382 1454 4.9E-9 T 01-11-2018 IPR030392 Intramolecular chaperone auto-processing domain MLA2C4_13125 91088a019830cb05ad6373960c0576cb 197 Gene3D G3DSA:3.40.50.150 11 175 1.3E-12 T 01-11-2018 MLA2C4_13125 91088a019830cb05ad6373960c0576cb 197 SUPERFAMILY SSF53335 38 175 4.07E-13 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_09220 c63668598712789db9e938766864f0b2 541 Pfam PF14158 YndJ-like protein 28 279 1.0E-82 T 01-11-2018 IPR025450 YndJ-like protein MLA2C4_12300 fc6b578ef1ec513d7a9838e45164cdd8 288 SUPERFAMILY SSF161098 72 267 2.09E-7 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_12300 fc6b578ef1ec513d7a9838e45164cdd8 288 Gene3D G3DSA:1.10.3720.10 61 288 1.3E-7 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_12300 fc6b578ef1ec513d7a9838e45164cdd8 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 281 1.8E-10 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_06825 8607029879d0e7f328274a3c3389401a 44 SUPERFAMILY SSF47406 8 35 4.84E-7 T 01-11-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 MLA2C4_06825 8607029879d0e7f328274a3c3389401a 44 Pfam PF08671 Anti-repressor SinI 9 36 8.4E-11 T 01-11-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 TIGRFAM TIGR00260 thrC: threonine synthase 8 322 3.0E-100 T 01-11-2018 IPR004450 Threonine synthase-like MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 PIRSF PIRSF038945 1 348 1.5E-155 T 01-11-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 Gene3D G3DSA:3.40.50.1100 12 322 6.5E-123 T 01-11-2018 MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 SUPERFAMILY SSF53686 6 349 1.44E-105 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 01-11-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 Gene3D G3DSA:3.40.50.1100 58 154 6.5E-123 T 01-11-2018 MLA2C4_10015 37f48d4572a0677bbf8e7ff52ee1459f 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 1.4E-79 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_06565 b414af0f4def1625c3dc7d9ca67c84f6 136 Pfam PF13048 Protein of unknown function (DUF3908) 4 126 4.3E-53 T 01-11-2018 IPR025020 Protein of unknown function DUF3908 MLA2C4_13895 d974662c530c33c5bea14ffe593364d6 112 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 1 94 8.5E-34 T 01-11-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family MLA2C4_24165 0c9d676f8ce6e523ed950950389c5fa1 314 SUPERFAMILY SSF103481 196 303 3.92E-5 T 01-11-2018 MLA2C4_24165 0c9d676f8ce6e523ed950950389c5fa1 314 SUPERFAMILY SSF103481 48 148 2.22E-8 T 01-11-2018 MLA2C4_24165 0c9d676f8ce6e523ed950950389c5fa1 314 Pfam PF00892 EamA-like transporter family 162 298 4.5E-13 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_24165 0c9d676f8ce6e523ed950950389c5fa1 314 Pfam PF00892 EamA-like transporter family 8 145 8.0E-24 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_03955 a4a3cc6d0e23944d9a1e97b56e5d2417 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 5 248 6.7E-107 T 01-11-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MLA2C4_03955 a4a3cc6d0e23944d9a1e97b56e5d2417 256 Gene3D G3DSA:3.20.20.70 1 256 9.4E-114 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_03955 a4a3cc6d0e23944d9a1e97b56e5d2417 256 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 41.648 T 01-11-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MLA2C4_03955 a4a3cc6d0e23944d9a1e97b56e5d2417 256 SUPERFAMILY SSF110399 1 239 3.14E-80 T 01-11-2018 MLA2C4_05590 f3e9a6c3dc2d95c952cef522ec339d92 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 382 1.0E-125 T 01-11-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 MLA2C4_05590 f3e9a6c3dc2d95c952cef522ec339d92 403 PIRSF PIRSF037259 1 403 4.1E-139 T 01-11-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 MLA2C4_16850 4fbf47c348e33754b3d9190450f92bdb 168 SUPERFAMILY SSF55729 2 165 4.22E-46 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_16850 4fbf47c348e33754b3d9190450f92bdb 168 Gene3D G3DSA:3.40.630.30 1 168 1.3E-55 T 01-11-2018 MLA2C4_16850 4fbf47c348e33754b3d9190450f92bdb 168 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 6.9E-30 T 01-11-2018 IPR000182 GNAT domain MLA2C4_13650 47b8ab4775d75afc44c092bee71e6a62 210 SUPERFAMILY SSF52317 4 178 4.76E-31 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_13650 47b8ab4775d75afc44c092bee71e6a62 210 Gene3D G3DSA:3.40.50.880 1 210 6.1E-56 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_13650 47b8ab4775d75afc44c092bee71e6a62 210 Pfam PF01965 DJ-1/PfpI family 4 176 6.0E-35 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_24860 0cb80b3f4e0af56de1bf12a61b91b783 714 SUPERFAMILY SSF53649 421 597 5.01E-17 T 01-11-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MLA2C4_24860 0cb80b3f4e0af56de1bf12a61b91b783 714 Gene3D G3DSA:3.40.720.10 345 654 7.1E-41 T 01-11-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MLA2C4_24860 0cb80b3f4e0af56de1bf12a61b91b783 714 Pfam PF00884 Sulfatase 352 648 1.2E-29 T 01-11-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MLA2C4_08920 4969c1fd63905370c31dbad7b64bf2a7 275 SUPERFAMILY SSF81606 101 237 3.14E-6 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_08920 4969c1fd63905370c31dbad7b64bf2a7 275 Pfam PF13672 Protein phosphatase 2C 126 238 6.7E-8 T 01-11-2018 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 1.1E-39 T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 01-11-2018 IPR002178 PTS EIIA type-2 domain MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 8.3E-41 T 01-11-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 171 260 4.8E-17 T 01-11-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 Gene3D G3DSA:3.40.50.2300 158 269 5.3E-41 T 01-11-2018 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 SUPERFAMILY SSF55804 1 148 6.41E-44 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 Gene3D G3DSA:3.40.930.10 1 150 2.1E-49 T 01-11-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 279 614 2.9E-125 T 01-11-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 171 252 5.7E-30 T 01-11-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 MLA2C4_19410 8c8ac1f25781c07d268b251a58ce07bf 618 SUPERFAMILY SSF52794 169 269 6.1E-36 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_03645 b7491bff8abbb52f87e8d61dcf86e643 515 SUPERFAMILY SSF52317 40 298 1.58E-10 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_03645 b7491bff8abbb52f87e8d61dcf86e643 515 Gene3D G3DSA:3.40.50.880 36 206 7.3E-6 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_06190 10cc2f86725d0895778dc3532db30d22 262 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 63 254 5.3E-49 T 01-11-2018 IPR018728 Domain of unknown function DUF2268 MLA2C4_17065 d9c99e999abe8255bff8195f43f19280 242 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 239 59.36 T 01-11-2018 IPR022822 Lactate utilization protein A GO:0006089 MLA2C4_17065 d9c99e999abe8255bff8195f43f19280 242 Pfam PF02754 Cysteine-rich domain 133 216 3.4E-14 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_17065 d9c99e999abe8255bff8195f43f19280 242 Pfam PF02754 Cysteine-rich domain 3 83 1.7E-16 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_06585 ba1dab517ea005c6405c250c2c7a2ebe 639 Gene3D G3DSA:3.40.50.720 168 331 2.4E-11 T 01-11-2018 MLA2C4_06585 ba1dab517ea005c6405c250c2c7a2ebe 639 TIGRFAM TIGR03693 ocin_ThiF_like: putative thiazole-containing bacteriocin maturation protein 1 637 0.0 T 01-11-2018 IPR022368 Putative thiazole-containing bacteriocin maturation protein MLA2C4_06585 ba1dab517ea005c6405c250c2c7a2ebe 639 SUPERFAMILY SSF69572 103 304 1.24E-5 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_14155 ba0534888dea19e3a5da3659b4e6318e 197 Gene3D G3DSA:3.40.630.30 1 161 2.1E-21 T 01-11-2018 MLA2C4_14155 ba0534888dea19e3a5da3659b4e6318e 197 SUPERFAMILY SSF55729 1 146 5.57E-24 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14155 ba0534888dea19e3a5da3659b4e6318e 197 Pfam PF00583 Acetyltransferase (GNAT) family 31 134 5.0E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_22175 b9bf2b270232ae087bc657c851d6be92 151 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 26 1.3E-7 T 01-11-2018 IPR012902 Prokaryotic N-terminal methylation site MLA2C4_22175 b9bf2b270232ae087bc657c851d6be92 151 SUPERFAMILY SSF54523 6 127 5.1E-11 T 01-11-2018 MLA2C4_22175 b9bf2b270232ae087bc657c851d6be92 151 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 9.4E-7 T 01-11-2018 IPR012902 Prokaryotic N-terminal methylation site MLA2C4_22175 b9bf2b270232ae087bc657c851d6be92 151 PIRSF PIRSF021292 1 144 5.5E-56 T 01-11-2018 IPR016785 ComG operon protein 4 GO:0030420 MLA2C4_22175 b9bf2b270232ae087bc657c851d6be92 151 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 01-11-2018 IPR012902 Prokaryotic N-terminal methylation site MLA2C4_08470 6e335d50d412824662a174a9540c03b7 241 Pfam PF01925 Sulfite exporter TauE/SafE 8 233 4.4E-31 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MLA2C4_09115 1e0920c37b7c3261d1294884c35f5f81 351 SUPERFAMILY SSF56281 8 324 1.15E-16 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_09115 1e0920c37b7c3261d1294884c35f5f81 351 Pfam PF00753 Metallo-beta-lactamase superfamily 24 115 1.1E-5 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_27180 a804c3df5430a1efa51b21876905b4a0 397 Gene3D G3DSA:1.10.287.470 108 195 1.5E-32 T 01-11-2018 MLA2C4_27180 a804c3df5430a1efa51b21876905b4a0 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 82 275 7.5E-10 T 01-11-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MLA2C4_27180 a804c3df5430a1efa51b21876905b4a0 397 Gene3D G3DSA:2.40.30.170 64 323 1.5E-32 T 01-11-2018 MLA2C4_27180 a804c3df5430a1efa51b21876905b4a0 397 Gene3D G3DSA:2.40.420.20 324 381 1.5E-32 T 01-11-2018 MLA2C4_27180 a804c3df5430a1efa51b21876905b4a0 397 Gene3D G3DSA:2.40.50.100 73 234 1.5E-32 T 01-11-2018 MLA2C4_03100 866bf67683d10a959541cf9fd686cc5c 170 Gene3D G3DSA:3.40.630.30 1 170 6.6E-43 T 01-11-2018 MLA2C4_03100 866bf67683d10a959541cf9fd686cc5c 170 Pfam PF00583 Acetyltransferase (GNAT) family 37 140 3.3E-19 T 01-11-2018 IPR000182 GNAT domain MLA2C4_03100 866bf67683d10a959541cf9fd686cc5c 170 SUPERFAMILY SSF55729 6 168 5.06E-29 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_19945 ec9565e2155e16a3e8f0cdfbd73d5333 90 Pfam PF04296 Protein of unknown function (DUF448) 9 81 4.5E-26 T 01-11-2018 IPR007393 Domain of unknown function DUF448 MLA2C4_19945 ec9565e2155e16a3e8f0cdfbd73d5333 90 SUPERFAMILY SSF64376 4 87 3.27E-27 T 01-11-2018 IPR035931 YlxR-like superfamily MLA2C4_19945 ec9565e2155e16a3e8f0cdfbd73d5333 90 Gene3D G3DSA:3.30.1230.10 1 90 9.5E-35 T 01-11-2018 IPR035931 YlxR-like superfamily MLA2C4_16820 23772016f680be1891700cff1149e751 769 Pfam PF13087 AAA domain 415 600 1.3E-27 T 01-11-2018 MLA2C4_16820 23772016f680be1891700cff1149e751 769 Gene3D G3DSA:3.40.50.300 426 636 2.0E-32 T 01-11-2018 MLA2C4_16820 23772016f680be1891700cff1149e751 769 SUPERFAMILY SSF52540 167 634 2.7E-43 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_16820 23772016f680be1891700cff1149e751 769 Pfam PF13086 AAA domain 174 384 6.2E-27 T 01-11-2018 MLA2C4_08945 8dc1991b96a1590a2916aaccbd69d839 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 287 1.3E-91 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_08945 8dc1991b96a1590a2916aaccbd69d839 299 SUPERFAMILY SSF161111 10 210 7.98E-59 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily MLA2C4_08945 8dc1991b96a1590a2916aaccbd69d839 299 Gene3D G3DSA:1.20.1510.10 12 209 2.1E-46 T 01-11-2018 IPR027469 Cation efflux transmembrane domain superfamily MLA2C4_08945 8dc1991b96a1590a2916aaccbd69d839 299 SUPERFAMILY SSF160240 213 285 1.44E-8 T 01-11-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MLA2C4_08945 8dc1991b96a1590a2916aaccbd69d839 299 Pfam PF01545 Cation efflux family 16 209 3.9E-52 T 01-11-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MLA2C4_21625 e93d83a7293f2f6261cdf6aa12497325 61 Pfam PF14164 YqzH-like protein 1 60 2.5E-24 T 01-11-2018 IPR025546 YqzH-like protein MLA2C4_16960 a922222ed23c4c5c9df7534c418e009b 410 Pfam PF13285 Domain of unknown function (DUF4073) 251 407 5.8E-92 T 01-11-2018 IPR025142 Domain of unknown function DUF4073 MLA2C4_16960 a922222ed23c4c5c9df7534c418e009b 410 Pfam PF00149 Calcineurin-like phosphoesterase 35 250 7.9E-14 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_16960 a922222ed23c4c5c9df7534c418e009b 410 SUPERFAMILY SSF56300 34 315 1.41E-32 T 01-11-2018 MLA2C4_08375 0d71259825d95a3350860688dd669bc8 242 Pfam PF08892 YqcI/YcgG family 29 236 4.7E-71 T 01-11-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 353 373 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 189 208 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 224 243 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 6.9E-52 T 01-11-2018 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 Pfam PF00375 Sodium:dicarboxylate symporter family 6 398 5.6E-133 T 01-11-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 Gene3D G3DSA:1.10.3860.10 1 411 3.5E-135 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_07345 1bc17f3f756430171cc0d6093bc7dd85 411 SUPERFAMILY SSF118215 6 400 3.4E-120 T 01-11-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MLA2C4_25675 803781a7bafb84c374323af32d3ef7ee 153 Pfam PF04463 Protein of unknown function (DUF523) 2 146 8.6E-43 T 01-11-2018 IPR007553 Domain of unknown function DUF523 MLA2C4_16380 45bf419648475b797f609f0dcd4faae1 406 Gene3D G3DSA:1.20.1170.10 267 405 2.1E-29 T 01-11-2018 MLA2C4_16380 45bf419648475b797f609f0dcd4faae1 406 Gene3D G3DSA:1.20.1170.10 40 266 1.2E-68 T 01-11-2018 MLA2C4_16380 45bf419648475b797f609f0dcd4faae1 406 SUPERFAMILY SSF58100 37 400 3.66E-84 T 01-11-2018 MLA2C4_16380 45bf419648475b797f609f0dcd4faae1 406 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 45 230 2.5E-66 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_07465 669c6056bceaecccc20fac3af1703b92 107 SUPERFAMILY SSF101386 8 93 1.45E-25 T 01-11-2018 MLA2C4_07465 669c6056bceaecccc20fac3af1703b92 107 Gene3D G3DSA:1.10.287.1080 2 95 3.4E-33 T 01-11-2018 MLA2C4_07465 669c6056bceaecccc20fac3af1703b92 107 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 7 87 1.0E-33 T 01-11-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MLA2C4_07465 669c6056bceaecccc20fac3af1703b92 107 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 10 92 4.1E-20 T 01-11-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MLA2C4_07465 669c6056bceaecccc20fac3af1703b92 107 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 20.687 T 01-11-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MLA2C4_17535 9a08a534b77ec3ba7731522e28eca982 342 Pfam PF00480 ROK family 117 235 2.8E-17 T 01-11-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MLA2C4_17535 9a08a534b77ec3ba7731522e28eca982 342 SUPERFAMILY SSF46785 14 78 5.81E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17535 9a08a534b77ec3ba7731522e28eca982 342 Gene3D G3DSA:1.10.10.10 12 78 1.7E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17535 9a08a534b77ec3ba7731522e28eca982 342 Gene3D G3DSA:3.30.420.40 200 238 5.9E-27 T 01-11-2018 MLA2C4_17535 9a08a534b77ec3ba7731522e28eca982 342 SUPERFAMILY SSF53067 85 249 4.13E-18 T 01-11-2018 MLA2C4_17535 9a08a534b77ec3ba7731522e28eca982 342 Gene3D G3DSA:3.30.420.40 87 199 5.9E-27 T 01-11-2018 MLA2C4_02665 2c762076b6ae48845e557cee103e0a78 185 Gene3D G3DSA:3.40.630.30 1 178 6.5E-21 T 01-11-2018 MLA2C4_02665 2c762076b6ae48845e557cee103e0a78 185 Pfam PF13302 Acetyltransferase (GNAT) domain 7 132 9.0E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_02665 2c762076b6ae48845e557cee103e0a78 185 SUPERFAMILY SSF55729 3 156 5.31E-21 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_12050 3994b34536f22c45f6a405f54fcfe958 111 Pfam PF08863 YolD-like protein 19 110 2.8E-20 T 01-11-2018 IPR014962 YolD-like protein MLA2C4_27780 ab6b786350ab40718d39d54f7f0a9647 328 Pfam PF02016 LD-carboxypeptidase 12 314 2.6E-74 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_27780 ab6b786350ab40718d39d54f7f0a9647 328 PIRSF PIRSF028757 1 328 2.1E-82 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_27780 ab6b786350ab40718d39d54f7f0a9647 328 SUPERFAMILY SSF141986 165 318 6.41E-35 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_27780 ab6b786350ab40718d39d54f7f0a9647 328 Gene3D G3DSA:3.50.30.60 159 328 2.8E-63 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_27780 ab6b786350ab40718d39d54f7f0a9647 328 SUPERFAMILY SSF52317 2 165 2.38E-45 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_27780 ab6b786350ab40718d39d54f7f0a9647 328 Gene3D G3DSA:3.40.50.10740 1 158 2.6E-61 T 01-11-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 Gene3D G3DSA:3.20.80.10 128 290 1.6E-40 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 SMART SM00342 21 104 6.3E-27 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 SUPERFAMILY SSF55136 128 290 7.59E-31 T 01-11-2018 IPR011256 Regulatory factor, effector binding domain superfamily MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 SUPERFAMILY SSF46689 6 55 7.62E-8 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 Gene3D G3DSA:1.10.10.60 58 116 5.5E-15 T 01-11-2018 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 SUPERFAMILY SSF46689 57 113 3.9E-12 T 01-11-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 Gene3D G3DSA:1.10.10.60 2 57 4.8E-14 T 01-11-2018 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 SMART SM00871 128 288 1.4E-34 T 01-11-2018 IPR010499 Bacterial transcription activator, effector binding MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 01-11-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 Pfam PF06445 GyrI-like small molecule binding domain 128 287 2.1E-29 T 01-11-2018 IPR029442 GyrI-like small molecule binding domain MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 Pfam PF12833 Helix-turn-helix domain 28 105 3.3E-17 T 01-11-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 5.1E-6 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_25150 93c72bc3852093e6fc0f5b5678a58cad 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 5.1E-6 T 01-11-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MLA2C4_22100 369e77e5057dbb1e1def165f0abde115 67 Pfam PF13066 Protein of unknown function (DUF3929) 1 64 6.9E-48 T 01-11-2018 IPR025171 Protein of unknown function DUF3929 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 SMART SM00028 172 205 84.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 SMART SM00028 91 124 150.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 SMART SM00028 212 245 66.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 SMART SM00028 131 164 32.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 SMART SM00028 246 279 97.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 Gene3D G3DSA:1.25.40.10 2 363 3.9E-88 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_05460 2c57e47928b95a7a2a1b1a63397facff 364 SUPERFAMILY SSF48452 93 307 1.25E-19 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_25825 603be483bbfa46a0e76da39f7b7ad49e 88 Pfam PF11256 Protein of unknown function (DUF3055) 7 85 1.2E-35 T 01-11-2018 IPR021415 Protein of unknown function DUF3055 MLA2C4_17810 3c63a49bb1c58c1fc2907fd2b42f471b 182 Pfam PF13302 Acetyltransferase (GNAT) domain 9 147 1.1E-27 T 01-11-2018 IPR000182 GNAT domain MLA2C4_17810 3c63a49bb1c58c1fc2907fd2b42f471b 182 SUPERFAMILY SSF55729 3 173 8.99E-43 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_17810 3c63a49bb1c58c1fc2907fd2b42f471b 182 Gene3D G3DSA:3.40.630.30 1 177 2.8E-43 T 01-11-2018 MLA2C4_06305 c55e2a496a8066ab6bcc0fe7f1c8ad49 212 Pfam PF04607 Region found in RelA / SpoT proteins 44 162 1.1E-37 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_06305 c55e2a496a8066ab6bcc0fe7f1c8ad49 212 SUPERFAMILY SSF81301 4 198 7.68E-60 T 01-11-2018 MLA2C4_06305 c55e2a496a8066ab6bcc0fe7f1c8ad49 212 Gene3D G3DSA:1.10.287.860 148 211 1.0E-28 T 01-11-2018 MLA2C4_06305 c55e2a496a8066ab6bcc0fe7f1c8ad49 212 SMART SM00954 44 165 2.4E-38 T 01-11-2018 IPR007685 RelA/SpoT GO:0015969 MLA2C4_06305 c55e2a496a8066ab6bcc0fe7f1c8ad49 212 Gene3D G3DSA:3.30.460.10 1 147 1.1E-51 T 01-11-2018 MLA2C4_10530 eefc837601fa0c837edb54101da520b4 401 Pfam PF08378 Nuclease-related domain 175 298 1.1E-11 T 01-11-2018 IPR011528 Nuclease-related domain, NERD MLA2C4_09640 36a27f30e74859e7ac8216204befcf9a 131 Pfam PF11070 Protein of unknown function (DUF2871) 1 128 6.1E-45 T 01-11-2018 IPR021299 Protein of unknown function DUF2871 MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 Gene3D G3DSA:3.40.190.290 91 296 6.7E-44 T 01-11-2018 MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 Pfam PF03466 LysR substrate binding domain 89 289 7.8E-45 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 SUPERFAMILY SSF53850 90 294 4.55E-44 T 01-11-2018 MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 Gene3D G3DSA:1.10.10.10 1 90 1.6E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 5.9E-21 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 SUPERFAMILY SSF46785 1 111 7.72E-25 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_26775 ddfa728cb4f15ccc656611f645482b4b 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-9 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_18760 3ccfa4b6f284c96a5b2c8913902a77e7 104 Gene3D G3DSA:3.40.50.720 2 104 2.4E-15 T 01-11-2018 MLA2C4_18760 3ccfa4b6f284c96a5b2c8913902a77e7 104 SUPERFAMILY SSF51735 10 97 5.38E-6 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_18760 3ccfa4b6f284c96a5b2c8913902a77e7 104 Pfam PF07993 Male sterility protein 10 97 4.5E-9 T 01-11-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 MLA2C4_23885 6b4ea4e83b9cdcc6925826d1d58a72c3 129 Pfam PF04186 FxsA cytoplasmic membrane protein 7 114 1.5E-34 T 01-11-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 MLA2C4_17090 06cbac9ed6d235ff32b987ba0362684b 343 SUPERFAMILY SSF52317 2 169 1.33E-43 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_17090 06cbac9ed6d235ff32b987ba0362684b 343 Pfam PF02016 LD-carboxypeptidase 14 328 3.6E-71 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_17090 06cbac9ed6d235ff32b987ba0362684b 343 SUPERFAMILY SSF141986 173 332 8.37E-26 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_17090 06cbac9ed6d235ff32b987ba0362684b 343 Gene3D G3DSA:3.40.50.10740 1 165 9.4E-65 T 01-11-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal MLA2C4_17090 06cbac9ed6d235ff32b987ba0362684b 343 Gene3D G3DSA:3.50.30.60 166 343 5.9E-62 T 01-11-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily MLA2C4_17090 06cbac9ed6d235ff32b987ba0362684b 343 PIRSF PIRSF028757 2 343 1.8E-66 T 01-11-2018 IPR003507 Peptidase family S66 MLA2C4_23595 f01816b0b408d40dbe4cfa0455db5c9a 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 63 7.5E-37 T 01-11-2018 IPR019240 Protein of unknown function DUF2196 MLA2C4_23595 f01816b0b408d40dbe4cfa0455db5c9a 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 3.2E-34 T 01-11-2018 IPR019240 Protein of unknown function DUF2196 MLA2C4_18630 7020aeec986b378ac9a01f40d674f3b0 123 SUPERFAMILY SSF54593 4 121 3.99E-20 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_18630 7020aeec986b378ac9a01f40d674f3b0 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 1.9E-12 T 01-11-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MLA2C4_18630 7020aeec986b378ac9a01f40d674f3b0 123 Gene3D G3DSA:3.10.180.10 8 123 3.7E-21 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_13085 aa1d763872f843e3935f6de46d4de19b 74 Pfam PF10779 Haemolysin XhlA 6 69 1.0E-11 T 01-11-2018 IPR019715 Haemolysin XhlA MLA2C4_15095 2bf6bf9324e09a9a218fa02ddfaea2c1 198 Gene3D G3DSA:3.40.50.880 2 197 3.3E-63 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_15095 2bf6bf9324e09a9a218fa02ddfaea2c1 198 SUPERFAMILY SSF52317 6 193 5.73E-50 T 01-11-2018 IPR029062 Class I glutamine amidotransferase-like MLA2C4_15095 2bf6bf9324e09a9a218fa02ddfaea2c1 198 Pfam PF01965 DJ-1/PfpI family 7 175 1.5E-29 T 01-11-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MLA2C4_26990 c4aaadb50c78c582ab7335ed8ec8cfb4 385 Pfam PF01757 Acyltransferase family 10 343 2.8E-31 T 01-11-2018 IPR002656 Acyltransferase 3 GO:0016747 MLA2C4_25720 94127f4137a8e8b5ccb65f3eaebfcf27 57 Gene3D G3DSA:1.20.58.990 1 57 1.9E-28 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_25720 94127f4137a8e8b5ccb65f3eaebfcf27 57 SUPERFAMILY SSF140500 1 52 7.46E-16 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_25720 94127f4137a8e8b5ccb65f3eaebfcf27 57 Pfam PF09388 Spo0E like sporulation regulatory protein 6 43 1.7E-15 T 01-11-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 MLA2C4_14310 0edf5fbc8d86165c43d0a8adce650812 271 Gene3D G3DSA:2.30.320.10 3 270 1.4E-97 T 01-11-2018 IPR035948 YwqG-like superfamily MLA2C4_14310 0edf5fbc8d86165c43d0a8adce650812 271 SUPERFAMILY SSF103032 7 270 7.19E-86 T 01-11-2018 IPR035948 YwqG-like superfamily MLA2C4_14310 0edf5fbc8d86165c43d0a8adce650812 271 Pfam PF09234 Domain of unknown function (DUF1963) 42 270 1.8E-68 T 01-11-2018 IPR015315 Protein of unknown function DUF1963 MLA2C4_24595 e7561aec5889201fea7c00a776cf9553 74 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.0E-16 T 01-11-2018 IPR019618 Spore germination protein GerPA/GerPF MLA2C4_21490 7a0312291103436727644d40c5086774 307 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 85 191 1.3E-10 T 01-11-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 MLA2C4_21490 7a0312291103436727644d40c5086774 307 SUPERFAMILY SSF53474 20 305 3.07E-50 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_21490 7a0312291103436727644d40c5086774 307 Gene3D G3DSA:3.40.50.1820 53 307 8.4E-42 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_00990 fd44bc78a8e1ef67abf53c0d30cc148e 168 Pfam PF07681 DoxX 16 114 1.8E-10 T 01-11-2018 IPR032808 DoxX family MLA2C4_08635 567c3ae27caa0156929e83cf4e6382f2 368 Gene3D G3DSA:3.30.750.140 234 350 3.3E-10 T 01-11-2018 IPR038610 FliK-like, C-terminal domain superfamily MLA2C4_08635 567c3ae27caa0156929e83cf4e6382f2 368 Pfam PF02120 Flagellar hook-length control protein FliK 264 334 5.5E-9 T 01-11-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal MLA2C4_24425 4b7abe0a69911dbc4d85014fb94edc6c 357 Gene3D G3DSA:3.40.630.10 11 340 9.4E-119 T 01-11-2018 MLA2C4_24425 4b7abe0a69911dbc4d85014fb94edc6c 357 SUPERFAMILY SSF101821 71 180 3.82E-31 T 01-11-2018 MLA2C4_24425 4b7abe0a69911dbc4d85014fb94edc6c 357 PIRSF PIRSF001123 2 356 3.0E-153 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_24425 4b7abe0a69911dbc4d85014fb94edc6c 357 SUPERFAMILY SSF53187 4 351 1.01E-70 T 01-11-2018 MLA2C4_24425 4b7abe0a69911dbc4d85014fb94edc6c 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 1.9E-112 T 01-11-2018 IPR008007 Peptidase M42 MLA2C4_24425 4b7abe0a69911dbc4d85014fb94edc6c 357 Gene3D G3DSA:2.40.30.40 75 162 9.4E-119 T 01-11-2018 IPR023367 Peptidase M42, domain 2 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 SUPERFAMILY SSF46626 141 252 9.03E-13 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 Gene3D G3DSA:1.10.760.10 182 253 3.1E-15 T 01-11-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 SUPERFAMILY SSF81648 21 156 7.46E-30 T 01-11-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 1.6E-12 T 01-11-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 PIRSF PIRSF036636 1 255 5.2E-154 T 01-11-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 81 160 1.8E-9 T 01-11-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MLA2C4_08015 4a52efc71da1ed7933fb4fd602aff2ce 255 Gene3D G3DSA:1.20.810.10 14 174 2.8E-25 T 01-11-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 MLA2C4_03340 f935ba6b512c49d0c35304340dbabb11 500 PIRSF PIRSF005690 11 491 3.7E-170 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_03340 f935ba6b512c49d0c35304340dbabb11 500 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 26 476 3.2E-172 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_18430 8faa61e64233a03f9f9be44686cb02a5 369 Pfam PF13354 Beta-lactamase enzyme family 60 301 9.7E-15 T 01-11-2018 MLA2C4_18430 8faa61e64233a03f9f9be44686cb02a5 369 Gene3D G3DSA:3.40.710.10 31 362 1.8E-36 T 01-11-2018 MLA2C4_18430 8faa61e64233a03f9f9be44686cb02a5 369 SUPERFAMILY SSF56601 42 350 2.97E-25 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_14360 f225c3d7d1ada9663a1e96d66bf0c307 259 Pfam PF02673 Bacitracin resistance protein BacA 6 249 1.2E-77 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_14360 f225c3d7d1ada9663a1e96d66bf0c307 259 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 254 17.522 T 01-11-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MLA2C4_17610 eeed5f04642a99356638b7f664ca0ce2 251 SUPERFAMILY SSF53335 13 247 1.02E-35 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_17610 eeed5f04642a99356638b7f664ca0ce2 251 Pfam PF08241 Methyltransferase domain 52 147 1.8E-17 T 01-11-2018 IPR013216 Methyltransferase type 11 GO:0008168 MLA2C4_17610 eeed5f04642a99356638b7f664ca0ce2 251 Gene3D G3DSA:3.40.50.150 40 251 1.6E-45 T 01-11-2018 MLA2C4_27945 46378a1adb22ddf9d59b2315147006aa 95 Pfam PF17261 Family of unknown function (DUF5327) 1 95 7.0E-23 T 01-11-2018 IPR035218 Protein of unknown function DUF5327 MLA2C4_27945 46378a1adb22ddf9d59b2315147006aa 95 ProDom PD705231 YWDI GROUP-SPECIFIC 1 95 2.0E-47 T 01-11-2018 IPR035218 Protein of unknown function DUF5327 MLA2C4_16615 dd701c67fba4a1a8b59724a88505f6d3 236 Pfam PF12695 Alpha/beta hydrolase family 60 222 2.3E-69 T 01-11-2018 IPR029059 Alpha/beta hydrolase fold-5 MLA2C4_16615 dd701c67fba4a1a8b59724a88505f6d3 236 SUPERFAMILY SSF53474 54 202 3.62E-21 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_16615 dd701c67fba4a1a8b59724a88505f6d3 236 Gene3D G3DSA:3.40.50.1820 48 217 2.8E-18 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_06015 8b52ef5c72ade5c95ce564ddd900877c 64 PIRSF PIRSF037666 1 59 1.5E-34 T 01-11-2018 IPR017257 Spore germination protein GerPD, predicted MLA2C4_18790 696ec01383d021cbc83d6e412b393c10 191 Gene3D G3DSA:3.40.30.10 21 191 1.8E-51 T 01-11-2018 MLA2C4_18790 696ec01383d021cbc83d6e412b393c10 191 ProSitePatterns PS00194 Thioredoxin family active site. 80 98 - T 01-11-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MLA2C4_18790 696ec01383d021cbc83d6e412b393c10 191 Pfam PF00578 AhpC/TSA family 52 172 2.0E-34 T 01-11-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MLA2C4_18790 696ec01383d021cbc83d6e412b393c10 191 SUPERFAMILY SSF52833 47 190 8.18E-48 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_05585 35ee6f2dd67c9f18c7317103a3901f42 247 SUPERFAMILY SSF52540 4 231 4.66E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_05585 35ee6f2dd67c9f18c7317103a3901f42 247 Gene3D G3DSA:3.40.50.300 3 246 3.9E-65 T 01-11-2018 MLA2C4_05585 35ee6f2dd67c9f18c7317103a3901f42 247 SMART SM00382 29 213 1.7E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_05585 35ee6f2dd67c9f18c7317103a3901f42 247 Pfam PF00005 ABC transporter 20 163 1.3E-32 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_22760 8e021134ce6a2dea179974b055267047 125 Gene3D G3DSA:3.10.129.10 1 124 3.6E-20 T 01-11-2018 MLA2C4_22760 8e021134ce6a2dea179974b055267047 125 SUPERFAMILY SSF54637 4 123 3.2E-22 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_22760 8e021134ce6a2dea179974b055267047 125 Pfam PF01575 MaoC like domain 10 101 7.1E-6 T 01-11-2018 IPR002539 MaoC-like dehydratase domain MLA2C4_11100 90b43d86586ef4694eecec61ecc20788 191 Pfam PF06042 Nucleotidyltransferase 25 186 8.2E-58 T 01-11-2018 IPR009267 Putative nucleotidyltransferase MLA2C4_02500 075441405919b5f616ba603b24d8f2c2 138 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 5 128 1.2E-17 T 01-11-2018 IPR038725 General stress protein, FMN-binding split barrel domain MLA2C4_02500 075441405919b5f616ba603b24d8f2c2 138 SUPERFAMILY SSF50475 3 128 4.68E-28 T 01-11-2018 MLA2C4_02500 075441405919b5f616ba603b24d8f2c2 138 Gene3D G3DSA:2.30.110.10 1 138 4.2E-41 T 01-11-2018 IPR012349 FMN-binding split barrel GO:0048037 MLA2C4_28095 9735cfb9fe8fd3177ad2bd9b14ae1fda 210 Pfam PF03458 UPF0126 domain 92 166 1.2E-20 T 01-11-2018 IPR005115 Uncharacterised domain UPF0126 MLA2C4_28095 9735cfb9fe8fd3177ad2bd9b14ae1fda 210 Pfam PF03458 UPF0126 domain 6 79 1.1E-19 T 01-11-2018 IPR005115 Uncharacterised domain UPF0126 MLA2C4_20725 26c697ff10ef60ec5ef723a27e78d601 130 Gene3D G3DSA:1.20.5.850 7 49 2.3E-10 T 01-11-2018 MLA2C4_20725 26c697ff10ef60ec5ef723a27e78d601 130 SUPERFAMILY SSF111171 4 128 6.15E-66 T 01-11-2018 IPR036294 Rbstp2229-like superfamily MLA2C4_20725 26c697ff10ef60ec5ef723a27e78d601 130 Pfam PF08968 Domain of unknown function (DUF1885) 2 129 1.1E-56 T 01-11-2018 IPR015062 Protein of unknown function DUF1885 MLA2C4_20725 26c697ff10ef60ec5ef723a27e78d601 130 Gene3D G3DSA:3.30.310.120 50 129 8.2E-30 T 01-11-2018 MLA2C4_19390 514fd08f25f532e1341c6d422a009697 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 31.451 T 01-11-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MLA2C4_19390 514fd08f25f532e1341c6d422a009697 74 Gene3D G3DSA:2.30.30.100 1 74 6.8E-35 T 01-11-2018 MLA2C4_19390 514fd08f25f532e1341c6d422a009697 74 Pfam PF17209 Hfq protein 7 69 5.4E-33 T 01-11-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MLA2C4_19390 514fd08f25f532e1341c6d422a009697 74 SUPERFAMILY SSF50182 6 65 2.25E-24 T 01-11-2018 IPR010920 LSM domain superfamily MLA2C4_19390 514fd08f25f532e1341c6d422a009697 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 2.7E-32 T 01-11-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MLA2C4_13070 beb707b00f2283cb91a8ead964c8242e 1298 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 98 434 2.3E-66 T 01-11-2018 IPR010090 Phage tail tape measure protein MLA2C4_13070 beb707b00f2283cb91a8ead964c8242e 1298 SUPERFAMILY SSF48371 687 1126 4.12E-14 T 01-11-2018 IPR016024 Armadillo-type fold MLA2C4_13070 beb707b00f2283cb91a8ead964c8242e 1298 Pfam PF10145 Phage-related minor tail protein 129 327 1.0E-49 T 01-11-2018 IPR010090 Phage tail tape measure protein MLA2C4_20380 d00e5c76ad15df398236e406ecc8b212 156 Gene3D G3DSA:3.30.110.150 59 155 2.9E-32 T 01-11-2018 IPR038594 SepF-like superfamily MLA2C4_20380 d00e5c76ad15df398236e406ecc8b212 156 Pfam PF04472 Cell division protein SepF 66 137 1.0E-29 T 01-11-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 MLA2C4_20380 d00e5c76ad15df398236e406ecc8b212 156 Hamap MF_01197 Cell division protein SepF [sepF]. 1 145 18.54 T 01-11-2018 IPR023052 Cell division protein SepF GO:0090529 MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 24.217 T 01-11-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 SUPERFAMILY SSF75420 4 84 7.45E-26 T 01-11-2018 IPR035956 RimP, N-terminal domain superfamily MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 1.7E-21 T 01-11-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 Gene3D G3DSA:3.30.300.70 2 81 2.9E-29 T 01-11-2018 IPR035956 RimP, N-terminal domain superfamily MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 Gene3D G3DSA:2.30.30.180 88 154 3.9E-23 T 01-11-2018 MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 Pfam PF02576 RimP N-terminal domain 13 84 1.2E-27 T 01-11-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MLA2C4_19955 50564bcd5987c9427ef3cd35cc5ca63f 156 SUPERFAMILY SSF74942 85 156 4.32E-21 T 01-11-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily MLA2C4_07270 da7cf6bbb560711e0a6d5379e21203e8 388 PIRSF PIRSF500216 1 388 2.1E-165 T 01-11-2018 IPR024024 D-alanyl transfer protein DltB MLA2C4_07270 da7cf6bbb560711e0a6d5379e21203e8 388 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 125 345 1.8E-17 T 01-11-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MLA2C4_07270 da7cf6bbb560711e0a6d5379e21203e8 388 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 384 1.7E-159 T 01-11-2018 IPR024024 D-alanyl transfer protein DltB MLA2C4_07270 da7cf6bbb560711e0a6d5379e21203e8 388 PIRSF PIRSF016636 2 385 1.8E-80 T 01-11-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MLA2C4_10980 6e04d37808e81944ef7287978bd2c2aa 258 SUPERFAMILY SSF53335 2 256 1.52E-54 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_10980 6e04d37808e81944ef7287978bd2c2aa 258 Gene3D G3DSA:3.40.50.150 71 255 2.0E-40 T 01-11-2018 MLA2C4_10980 6e04d37808e81944ef7287978bd2c2aa 258 Pfam PF04445 Putative SAM-dependent methyltransferase 42 250 1.1E-16 T 01-11-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MLA2C4_13665 78a1a547f0b417a4bf12b469492fbf7a 408 Gene3D G3DSA:1.20.1250.20 16 400 5.2E-38 T 01-11-2018 MLA2C4_13665 78a1a547f0b417a4bf12b469492fbf7a 408 Pfam PF07690 Major Facilitator Superfamily 23 370 6.7E-28 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_13665 78a1a547f0b417a4bf12b469492fbf7a 408 SUPERFAMILY SSF103473 19 404 7.32E-44 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_22820 6b642326fe3ab4eb901eaa876fbd36ed 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 46.734 T 01-11-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_22820 6b642326fe3ab4eb901eaa876fbd36ed 231 Pfam PF01048 Phosphorylase superfamily 2 227 1.1E-53 T 01-11-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MLA2C4_22820 6b642326fe3ab4eb901eaa876fbd36ed 231 Gene3D G3DSA:3.40.50.1580 1 231 4.6E-75 T 01-11-2018 MLA2C4_22820 6b642326fe3ab4eb901eaa876fbd36ed 231 SUPERFAMILY SSF53167 2 230 1.02E-71 T 01-11-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MLA2C4_22820 6b642326fe3ab4eb901eaa876fbd36ed 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 3.5E-117 T 01-11-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MLA2C4_08860 e0a03e20e8298e5804c7251e141447e7 277 Gene3D G3DSA:2.40.320.10 32 157 9.2E-6 T 01-11-2018 MLA2C4_21930 e0084b2d6c19a166e72f299628b24297 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 2.6E-71 T 01-11-2018 IPR014198 Stage III sporulation protein AB MLA2C4_21930 e0084b2d6c19a166e72f299628b24297 171 PIRSF PIRSF021435 1 171 4.6E-74 T 01-11-2018 IPR014198 Stage III sporulation protein AB MLA2C4_21930 e0084b2d6c19a166e72f299628b24297 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 2.0E-56 T 01-11-2018 IPR014198 Stage III sporulation protein AB MLA2C4_06525 9a575310745622a44e81eaaf11f43018 98 Pfam PF13221 Protein of unknown function (DUF4029) 1 96 1.8E-57 T 01-11-2018 IPR025107 Protein of unknown function DUF4029 MLA2C4_03675 89c0a5c2ba4528217d0f2705c7c0983f 79 Pfam PF13214 Protein of unknown function (DUF4022) 1 76 3.3E-49 T 01-11-2018 IPR025095 Protein of unknown function DUF4022 MLA2C4_07315 93f9c2d94ad9b50d06330d72883ce639 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 1.2E-107 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_07315 93f9c2d94ad9b50d06330d72883ce639 454 Pfam PF01554 MatE 20 180 8.2E-34 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_07315 93f9c2d94ad9b50d06330d72883ce639 454 Pfam PF01554 MatE 247 408 2.3E-37 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_07315 93f9c2d94ad9b50d06330d72883ce639 454 PIRSF PIRSF006603 1 454 1.2E-76 T 01-11-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MLA2C4_11855 e07c37be1614e0a589c3da1d9c368527 215 Gene3D G3DSA:2.30.30.40 151 215 1.7E-9 T 01-11-2018 MLA2C4_19220 f1e7c027a8ecb1eb6a4a5e010407731f 107 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 2.2E-21 T 01-11-2018 IPR005149 Transcription regulator PadR, N-terminal MLA2C4_19220 f1e7c027a8ecb1eb6a4a5e010407731f 107 SUPERFAMILY SSF46785 10 103 1.07E-24 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_19220 f1e7c027a8ecb1eb6a4a5e010407731f 107 Gene3D G3DSA:1.10.10.10 2 106 9.2E-35 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_26095 935adb232f7a1363b52a43cc93b6eba8 340 Pfam PF01391 Collagen triple helix repeat (20 copies) 107 162 1.3E-6 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_26095 935adb232f7a1363b52a43cc93b6eba8 340 Pfam PF01391 Collagen triple helix repeat (20 copies) 146 198 8.4E-8 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_26095 935adb232f7a1363b52a43cc93b6eba8 340 Pfam PF01391 Collagen triple helix repeat (20 copies) 70 125 2.1E-8 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_26095 935adb232f7a1363b52a43cc93b6eba8 340 Pfam PF01391 Collagen triple helix repeat (20 copies) 9 65 8.0E-9 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_26095 935adb232f7a1363b52a43cc93b6eba8 340 SUPERFAMILY SSF49842 239 317 7.01E-6 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_09450 f75d866e154c57de8510dcdf29b64fc4 76 Pfam PF13710 ACT domain 12 73 2.2E-13 T 01-11-2018 MLA2C4_09450 f75d866e154c57de8510dcdf29b64fc4 76 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-37 T 01-11-2018 MLA2C4_09450 f75d866e154c57de8510dcdf29b64fc4 76 Gene3D G3DSA:3.30.70.260 1 76 3.8E-20 T 01-11-2018 MLA2C4_09450 f75d866e154c57de8510dcdf29b64fc4 76 SUPERFAMILY SSF55021 1 74 4.58E-14 T 01-11-2018 MLA2C4_22785 2af9220d12bc5b544ce40e3bc6773f5d 342 Pfam PF01032 FecCD transport family 28 334 8.1E-98 T 01-11-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MLA2C4_22785 2af9220d12bc5b544ce40e3bc6773f5d 342 Gene3D G3DSA:1.10.3470.10 15 339 4.7E-98 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_22785 2af9220d12bc5b544ce40e3bc6773f5d 342 SUPERFAMILY SSF81345 12 334 2.48E-84 T 01-11-2018 IPR037294 ABC transporter, BtuC-like MLA2C4_05740 a55de3d6bcee776a764c9c2c7e458552 133 Gene3D G3DSA:1.10.4040.10 74 125 5.3E-16 T 01-11-2018 MLA2C4_05740 a55de3d6bcee776a764c9c2c7e458552 133 Pfam PF03965 Penicillinase repressor 8 123 1.5E-39 T 01-11-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MLA2C4_05740 a55de3d6bcee776a764c9c2c7e458552 133 Gene3D G3DSA:1.10.10.10 9 73 2.5E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05740 a55de3d6bcee776a764c9c2c7e458552 133 PIRSF PIRSF019455 1 133 2.8E-41 T 01-11-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MLA2C4_05740 a55de3d6bcee776a764c9c2c7e458552 133 SUPERFAMILY SSF46785 6 126 1.17E-35 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_15630 28eeb3f0e6adc88a9b4e09303b5a17ca 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 01-11-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MLA2C4_15630 28eeb3f0e6adc88a9b4e09303b5a17ca 263 Gene3D G3DSA:3.90.226.10 1 204 1.6E-71 T 01-11-2018 MLA2C4_15630 28eeb3f0e6adc88a9b4e09303b5a17ca 263 SUPERFAMILY SSF52096 6 263 4.46E-87 T 01-11-2018 IPR029045 ClpP/crotonase-like domain superfamily MLA2C4_15630 28eeb3f0e6adc88a9b4e09303b5a17ca 263 Gene3D G3DSA:1.10.12.10 208 261 8.7E-17 T 01-11-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MLA2C4_15630 28eeb3f0e6adc88a9b4e09303b5a17ca 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 3.1E-63 T 01-11-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MLA2C4_19665 fb3ffce4c1d7fb2943144557b0e64902 445 Gene3D G3DSA:3.50.50.60 1 93 3.9E-12 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_19665 fb3ffce4c1d7fb2943144557b0e64902 445 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 34 1.1E-4 T 01-11-2018 MLA2C4_19665 fb3ffce4c1d7fb2943144557b0e64902 445 Gene3D G3DSA:3.50.50.60 108 218 1.4E-6 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_19665 fb3ffce4c1d7fb2943144557b0e64902 445 PIRSF PIRSF038984 2 84 0.0056 T 01-11-2018 IPR028348 FAD dependent protein MLA2C4_19665 fb3ffce4c1d7fb2943144557b0e64902 445 PIRSF PIRSF038984 123 444 1.7E-11 T 01-11-2018 IPR028348 FAD dependent protein MLA2C4_19665 fb3ffce4c1d7fb2943144557b0e64902 445 SUPERFAMILY SSF51905 2 442 1.14E-25 T 01-11-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MLA2C4_01810 e15b1e899b72d91b042440538dc04f28 54 Gene3D G3DSA:1.10.1220.10 1 50 1.1E-11 T 01-11-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MLA2C4_01810 e15b1e899b72d91b042440538dc04f28 54 SUPERFAMILY SSF47598 2 47 2.06E-11 T 01-11-2018 IPR010985 Ribbon-helix-helix GO:0006355 MLA2C4_01810 e15b1e899b72d91b042440538dc04f28 54 Pfam PF05534 HicB family 4 38 3.9E-5 T 01-11-2018 IPR008651 Uncharacterised protein family HicB MLA2C4_17885 49957315d6ab1ac9825c93de4123f1c5 319 Gene3D G3DSA:1.10.10.10 1 63 3.1E-7 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17885 49957315d6ab1ac9825c93de4123f1c5 319 SUPERFAMILY SSF46785 1 63 8.51E-8 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17885 49957315d6ab1ac9825c93de4123f1c5 319 Pfam PF08279 HTH domain 6 60 6.4E-12 T 01-11-2018 IPR013196 Helix-turn-helix, type 11 MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-36 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.1E-36 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.1E-36 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.1E-36 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.1E-36 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.1E-36 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 Gene3D G3DSA:3.40.50.720 1 237 9.1E-63 T 01-11-2018 MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 SUPERFAMILY SSF51735 2 236 3.84E-66 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_19800 e83fce82652d9b99ba574e04d3a3bd5b 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 9.2E-48 T 01-11-2018 MLA2C4_15845 1a83c30bdf9a39531b1e2ea415433fe8 127 Pfam PF12681 Glyoxalase-like domain 5 127 7.5E-45 T 01-11-2018 IPR025870 Glyoxalase-like domain MLA2C4_15845 1a83c30bdf9a39531b1e2ea415433fe8 127 Gene3D G3DSA:3.10.180.10 1 127 2.4E-27 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_15845 1a83c30bdf9a39531b1e2ea415433fe8 127 SUPERFAMILY SSF54593 4 124 1.88E-26 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_25180 301f744cb737ef8c1bc31899e7c1a9ae 651 PIRSF PIRSF018968 1 649 3.1E-125 T 01-11-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 MLA2C4_25180 301f744cb737ef8c1bc31899e7c1a9ae 651 Pfam PF02687 FtsX-like permease family 84 168 3.3E-8 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_06370 690937ffe8fc701563676f63509df6a9 226 Pfam PF13712 Glycosyltransferase like family 8 219 1.6E-81 T 01-11-2018 MLA2C4_06370 690937ffe8fc701563676f63509df6a9 226 SUPERFAMILY SSF53448 8 215 1.91E-7 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_06370 690937ffe8fc701563676f63509df6a9 226 Gene3D G3DSA:3.90.550.10 6 226 5.5E-43 T 01-11-2018 IPR029044 Nucleotide-diphospho-sugar transferases MLA2C4_12325 0c391e5407daf9e9d14063b76c9c0951 245 Pfam PF02535 ZIP Zinc transporter 93 237 8.0E-15 T 01-11-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 MLA2C4_00365 0df7fcbd98e33d18760bfca99839f581 180 SUPERFAMILY SSF53271 4 178 7.47E-60 T 01-11-2018 IPR029057 Phosphoribosyltransferase-like MLA2C4_00365 0df7fcbd98e33d18760bfca99839f581 180 Pfam PF00156 Phosphoribosyl transferase domain 15 160 2.6E-24 T 01-11-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MLA2C4_00365 0df7fcbd98e33d18760bfca99839f581 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 1.8E-68 T 01-11-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 MLA2C4_00365 0df7fcbd98e33d18760bfca99839f581 180 Gene3D G3DSA:3.40.50.2020 1 180 4.1E-67 T 01-11-2018 MLA2C4_21700 c4c22f420cde6a8f65cf60cbaac0f82b 79 Pfam PF13033 Protein of unknown function (DUF3894) 24 77 7.2E-36 T 01-11-2018 IPR024993 Protein of unknown function DUF3894 MLA2C4_10060 429c1af190b6b0c1dd45628c8c3e5ab1 218 Gene3D G3DSA:1.20.120.570 12 207 8.7E-38 T 01-11-2018 IPR036785 YkyA-like superfamily MLA2C4_10060 429c1af190b6b0c1dd45628c8c3e5ab1 218 SUPERFAMILY SSF140423 20 209 6.67E-57 T 01-11-2018 IPR036785 YkyA-like superfamily MLA2C4_10060 429c1af190b6b0c1dd45628c8c3e5ab1 218 Pfam PF10368 Putative cell-wall binding lipoprotein 12 212 9.4E-62 T 01-11-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like MLA2C4_28420 cfce64948503d514c2752721f1fb0521 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 60 4.6E-30 T 01-11-2018 IPR009296 Protein of unknown function DUF951 MLA2C4_28420 cfce64948503d514c2752721f1fb0521 65 PIRSF PIRSF037263 1 65 3.4E-35 T 01-11-2018 IPR009296 Protein of unknown function DUF951 MLA2C4_12315 c4ccf7723e220cbc6de449979cfc8c57 281 Pfam PF10978 Protein of unknown function (DUF2785) 83 253 7.7E-52 T 01-11-2018 IPR021247 Protein of unknown function DUF2785 MLA2C4_02425 dd876ba1c691d04d2050ddee3d0684fe 543 Pfam PF14266 Putative component of 'biosynthetic module' 40 525 1.7E-162 T 01-11-2018 IPR025647 Putative component of 'biosynthetic module' MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 SUPERFAMILY SSF46785 1 106 5.14E-20 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.4E-17 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 SUPERFAMILY SSF53850 91 245 9.41E-9 T 01-11-2018 MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 Gene3D G3DSA:3.40.190.290 91 256 2.3E-5 T 01-11-2018 MLA2C4_09835 0cc86a416e8d5a6276eaca00ebc2160c 262 Gene3D G3DSA:1.10.10.10 1 90 2.5E-22 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_19605 0bc521f9dd0bca157bc92a3ae0a3ef05 392 Pfam PF10720 Protein of unknown function (DUF2515) 51 381 4.3E-128 T 01-11-2018 IPR019658 Protein of unknown function DUF2515 MLA2C4_00875 c4526024ca0dd4833868734e6e74bc1c 254 Gene3D G3DSA:3.20.20.370 47 254 1.4E-59 T 01-11-2018 MLA2C4_00875 c4526024ca0dd4833868734e6e74bc1c 254 Pfam PF01522 Polysaccharide deacetylase 55 175 3.1E-25 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_00875 c4526024ca0dd4833868734e6e74bc1c 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 7.7E-85 T 01-11-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB MLA2C4_00875 c4526024ca0dd4833868734e6e74bc1c 254 SUPERFAMILY SSF88713 14 243 5.12E-54 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_09015 f5d021255875a036d1be25d8036f5fac 138 Gene3D G3DSA:1.10.10.10 14 81 3.2E-16 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_09015 f5d021255875a036d1be25d8036f5fac 138 Pfam PF03965 Penicillinase repressor 18 131 7.5E-27 T 01-11-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MLA2C4_09015 f5d021255875a036d1be25d8036f5fac 138 PIRSF PIRSF019455 12 138 2.1E-21 T 01-11-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MLA2C4_09015 f5d021255875a036d1be25d8036f5fac 138 SUPERFAMILY SSF46785 18 130 1.34E-19 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_26870 87100ed01740cbf2a352b9a31a665054 471 Gene3D G3DSA:3.90.1720.10 268 466 5.0E-36 T 01-11-2018 MLA2C4_26870 87100ed01740cbf2a352b9a31a665054 471 SUPERFAMILY SSF54001 354 471 6.38E-31 T 01-11-2018 IPR038765 Papain-like cysteine peptidase superfamily MLA2C4_26870 87100ed01740cbf2a352b9a31a665054 471 Pfam PF00877 NlpC/P60 family 370 468 8.7E-22 T 01-11-2018 IPR000064 Endopeptidase, NLPC/P60 domain MLA2C4_23465 3ce622658e9773cd5a7f2a875e119da2 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 218 1.1E-24 T 01-11-2018 IPR002898 MotA/TolQ/ExbB proton channel MLA2C4_23465 3ce622658e9773cd5a7f2a875e119da2 264 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 187 204 - T 01-11-2018 IPR000540 Flagellar motor protein MotA, conserved site MLA2C4_19200 82156c814c909adcfa5b3df0f2b9d7a2 218 SUPERFAMILY SSF53041 1 149 1.31E-25 T 01-11-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MLA2C4_19200 82156c814c909adcfa5b3df0f2b9d7a2 218 SMART SM00857 3 149 1.6E-34 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_19200 82156c814c909adcfa5b3df0f2b9d7a2 218 Gene3D G3DSA:3.40.50.1390 1 158 6.1E-27 T 01-11-2018 MLA2C4_19200 82156c814c909adcfa5b3df0f2b9d7a2 218 Pfam PF00239 Resolvase, N terminal domain 3 147 2.0E-26 T 01-11-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MLA2C4_25535 fcc17c6d3e6235dec51844019fb505be 83 Pfam PF08958 Domain of unknown function (DUF1871) 6 82 8.1E-37 T 01-11-2018 IPR015053 Protein of unknown function DUF1871 MLA2C4_25535 fcc17c6d3e6235dec51844019fb505be 83 ProDom PD062625 YUGE 1 83 4.0E-34 T 01-11-2018 IPR015053 Protein of unknown function DUF1871 MLA2C4_25535 fcc17c6d3e6235dec51844019fb505be 83 SUPERFAMILY SSF116922 3 78 8.5E-27 T 01-11-2018 IPR023162 Apc36109-like domain superfamily MLA2C4_25535 fcc17c6d3e6235dec51844019fb505be 83 Gene3D G3DSA:1.10.340.20 2 83 1.1E-29 T 01-11-2018 IPR023162 Apc36109-like domain superfamily MLA2C4_08680 6947acacc623343e14ab7e1c0124028c 259 Gene3D G3DSA:1.10.530.10 61 256 2.2E-43 T 01-11-2018 MLA2C4_08680 6947acacc623343e14ab7e1c0124028c 259 SUPERFAMILY SSF53955 134 254 2.65E-39 T 01-11-2018 IPR023346 Lysozyme-like domain superfamily MLA2C4_08680 6947acacc623343e14ab7e1c0124028c 259 Pfam PF01464 Transglycosylase SLT domain 143 244 1.5E-24 T 01-11-2018 IPR008258 Transglycosylase SLT domain 1 MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.7E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 4.7E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 4.7E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 4.7E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 4.7E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.7E-25 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.3E-6 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.3E-6 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.3E-6 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 252 2.7E-41 T 01-11-2018 MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 SUPERFAMILY SSF51735 2 251 4.03E-59 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_17460 7d63e5755fbfdac053ad58541c984ce5 252 Gene3D G3DSA:3.40.50.720 2 252 1.0E-57 T 01-11-2018 MLA2C4_19430 1661868d9997e53925d5a360e1c14b01 180 Pfam PF04238 Protein of unknown function (DUF420) 47 175 2.1E-43 T 01-11-2018 IPR007352 Protein of unknown function DUF420 MLA2C4_20650 f709edd488f8f108f35fd21b921f2fce 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 5.4E-31 T 01-11-2018 IPR019241 Protein of unknown function DUF2197 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 Gene3D G3DSA:1.20.1250.20 3 393 6.9E-75 T 01-11-2018 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 SUPERFAMILY SSF103473 8 394 7.46E-75 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.9E-23 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 PRINTS PR01035 Tetracycline resistance protein signature 164 184 1.9E-23 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 PRINTS PR01035 Tetracycline resistance protein signature 21 37 1.9E-23 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 PRINTS PR01035 Tetracycline resistance protein signature 78 102 1.9E-23 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.9E-23 T 01-11-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MLA2C4_04575 0ce785e55c5b1420e850d9c53a3c37a2 400 Pfam PF07690 Major Facilitator Superfamily 16 357 4.5E-55 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_20520 46d92b4341d89bff142a5023223b6fc8 263 Gene3D G3DSA:3.40.1090.20 108 177 7.1E-6 T 01-11-2018 MLA2C4_20520 46d92b4341d89bff142a5023223b6fc8 263 Pfam PF01734 Patatin-like phospholipase 8 74 3.0E-10 T 01-11-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MLA2C4_20520 46d92b4341d89bff142a5023223b6fc8 263 Pfam PF01734 Patatin-like phospholipase 124 164 4.0E-9 T 01-11-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MLA2C4_20520 46d92b4341d89bff142a5023223b6fc8 263 Gene3D G3DSA:3.40.1090.10 1 107 1.1E-26 T 01-11-2018 MLA2C4_20520 46d92b4341d89bff142a5023223b6fc8 263 SUPERFAMILY SSF52151 1 252 2.62E-54 T 01-11-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MLA2C4_01965 399deb1f0871923637dd81455601d4d5 398 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 190 397 3.7E-53 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_01965 399deb1f0871923637dd81455601d4d5 398 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 9.1E-18 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_25975 27178c0695540027b8eca68fcd6dd8a5 80 Pfam PF13073 Protein of unknown function (DUF3937) 1 72 7.0E-48 T 01-11-2018 IPR025068 Protein of unknown function DUF3937 MLA2C4_17520 7ac322288849db1d67c70062dbd29976 279 Pfam PF10978 Protein of unknown function (DUF2785) 80 253 2.8E-49 T 01-11-2018 IPR021247 Protein of unknown function DUF2785 MLA2C4_02360 bd5141a6645879cfb0a4a7d2ae2c0d46 410 SUPERFAMILY SSF103473 6 400 4.84E-49 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_02360 bd5141a6645879cfb0a4a7d2ae2c0d46 410 Pfam PF05977 Transmembrane secretion effector 5 399 1.1E-24 T 01-11-2018 IPR010290 Transmembrane secretion effector MLA2C4_02360 bd5141a6645879cfb0a4a7d2ae2c0d46 410 Gene3D G3DSA:1.20.1250.20 4 391 5.5E-40 T 01-11-2018 MLA2C4_24350 c61bacc63fab78135a120b672ff5b4ec 163 Gene3D G3DSA:3.40.630.30 2 163 2.9E-40 T 01-11-2018 MLA2C4_24350 c61bacc63fab78135a120b672ff5b4ec 163 Pfam PF00583 Acetyltransferase (GNAT) family 23 137 1.7E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_24350 c61bacc63fab78135a120b672ff5b4ec 163 SUPERFAMILY SSF55729 16 160 1.2E-20 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_22470 50ae88c77c9132344518b09fbe7b2897 117 Gene3D G3DSA:1.10.3830.10 1 116 4.7E-41 T 01-11-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MLA2C4_22470 50ae88c77c9132344518b09fbe7b2897 117 Pfam PF01219 Prokaryotic diacylglycerol kinase 11 112 1.5E-37 T 01-11-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MLA2C4_22470 50ae88c77c9132344518b09fbe7b2897 117 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 65 76 - T 01-11-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 SMART SM00346 2 94 6.3E-15 T 01-11-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 Gene3D G3DSA:1.10.10.10 1 77 3.6E-19 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 Pfam PF01614 Bacterial transcriptional regulator 123 240 6.5E-21 T 01-11-2018 IPR014757 Transcription regulator IclR, C-terminal MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 SUPERFAMILY SSF55781 70 244 5.23E-36 T 01-11-2018 MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 Gene3D G3DSA:3.30.450.40 78 247 5.6E-42 T 01-11-2018 IPR029016 GAF-like domain superfamily MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 SUPERFAMILY SSF46785 2 77 7.57E-15 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_15755 413a2cf292149c09515fcdd1cc31b3b2 249 Pfam PF09339 IclR helix-turn-helix domain 4 55 1.6E-15 T 01-11-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MLA2C4_17675 aa28ec8a575c6f102532a911787fbf64 351 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 6 348 3.2E-150 T 01-11-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 MLA2C4_17675 aa28ec8a575c6f102532a911787fbf64 351 Gene3D G3DSA:3.40.50.720 2 189 9.6E-49 T 01-11-2018 MLA2C4_17675 aa28ec8a575c6f102532a911787fbf64 351 SUPERFAMILY SSF51735 5 334 5.99E-67 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_17675 aa28ec8a575c6f102532a911787fbf64 351 Pfam PF16363 GDP-mannose 4,6 dehydratase 13 321 4.1E-38 T 01-11-2018 IPR016040 NAD(P)-binding domain MLA2C4_17675 aa28ec8a575c6f102532a911787fbf64 351 Gene3D G3DSA:3.90.25.10 190 351 3.6E-60 T 01-11-2018 MLA2C4_26310 3eb29660814da548faf4c5a55e6a50da 168 Pfam PF00210 Ferritin-like domain 8 144 2.2E-41 T 01-11-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MLA2C4_26310 3eb29660814da548faf4c5a55e6a50da 168 Gene3D G3DSA:1.20.1260.10 1 168 2.9E-51 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_26310 3eb29660814da548faf4c5a55e6a50da 168 SUPERFAMILY SSF47240 1 160 3.08E-58 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_05430 671ee2b7d7d0d082ccd87c09f51858ad 475 Pfam PF00144 Beta-lactamase 44 358 1.3E-59 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_05430 671ee2b7d7d0d082ccd87c09f51858ad 475 SUPERFAMILY SSF56601 26 365 1.83E-73 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_05430 671ee2b7d7d0d082ccd87c09f51858ad 475 Gene3D G3DSA:3.40.710.10 32 368 1.8E-86 T 01-11-2018 MLA2C4_06765 f5109e6b26183d1fe3e97c2ad7f4db8d 248 Pfam PF14335 Domain of unknown function (DUF4391) 10 229 1.8E-25 T 01-11-2018 IPR025503 Protein of unknown function DUF4391 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.3E-13 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 Gene3D G3DSA:3.40.190.290 92 296 2.4E-41 T 01-11-2018 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 Gene3D G3DSA:1.10.10.10 1 91 1.4E-16 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 SUPERFAMILY SSF53850 90 295 5.43E-39 T 01-11-2018 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 SUPERFAMILY SSF46785 2 111 2.73E-17 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-5 T 01-11-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MLA2C4_08835 669beef7fbdbc0959add5024d7ecc3f2 297 Pfam PF03466 LysR substrate binding domain 90 283 1.7E-39 T 01-11-2018 IPR005119 LysR, substrate-binding MLA2C4_25145 c984271747f8cb0bfbda7e0569ca8b9d 256 SMART SM00382 33 221 1.3E-8 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25145 c984271747f8cb0bfbda7e0569ca8b9d 256 Pfam PF00005 ABC transporter 24 172 1.0E-31 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_25145 c984271747f8cb0bfbda7e0569ca8b9d 256 SUPERFAMILY SSF52540 4 228 3.44E-69 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25145 c984271747f8cb0bfbda7e0569ca8b9d 256 Gene3D G3DSA:3.40.50.300 1 249 2.6E-65 T 01-11-2018 MLA2C4_13005 e699e79c6dc3a23859d648c6ae6d4b53 374 Pfam PF17236 Family of unknown function (DUF5309) 133 360 1.0E-30 T 01-11-2018 IPR035198 Protein of unknown function DUF5309 MLA2C4_23925 2c390a891400f3f9f3b60b2b6f61fa05 137 Pfam PF14034 Sporulation protein YtrH 37 134 3.1E-37 T 01-11-2018 IPR025689 Sporulation protein YtrH MLA2C4_16090 8bd7f138d8a041afcff03541370cb960 336 Pfam PF01925 Sulfite exporter TauE/SafE 44 280 1.8E-38 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MLA2C4_09185 38c311bd9fc0e566825e8f842ae7b13d 515 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 330 410 6.4E-21 T 01-11-2018 IPR010095 Transposase IS605, OrfB, C-terminal MLA2C4_09185 38c311bd9fc0e566825e8f842ae7b13d 515 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 4 79 4.5E-24 T 01-11-2018 IPR010094 Transposase (putative), N-terminal MLA2C4_04565 751ddcf8f5e8360febda83d522497661 104 SUPERFAMILY SSF103481 4 100 8.63E-15 T 01-11-2018 MLA2C4_04565 751ddcf8f5e8360febda83d522497661 104 Gene3D G3DSA:1.10.3730.20 1 104 3.2E-19 T 01-11-2018 MLA2C4_04565 751ddcf8f5e8360febda83d522497661 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.4E-23 T 01-11-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MLA2C4_02310 ca61732024da0d58993f1fe565ee9990 332 Pfam PF09084 NMT1/THI5 like 44 258 5.7E-78 T 01-11-2018 IPR015168 SsuA/THI5-like MLA2C4_02310 ca61732024da0d58993f1fe565ee9990 332 Gene3D G3DSA:3.40.190.10 116 218 2.0E-101 T 01-11-2018 MLA2C4_02310 ca61732024da0d58993f1fe565ee9990 332 SUPERFAMILY SSF53850 37 320 1.34E-45 T 01-11-2018 MLA2C4_02310 ca61732024da0d58993f1fe565ee9990 332 Gene3D G3DSA:3.40.190.10 39 327 2.0E-101 T 01-11-2018 MLA2C4_20290 77b261e43c704b47157b843ad0c90e9e 84 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 1 84 5.0E-38 T 01-11-2018 IPR020258 Uncharacterised protein family YbeF MLA2C4_20290 77b261e43c704b47157b843ad0c90e9e 84 Pfam PF10852 Protein of unknown function (DUF2651) 6 77 5.0E-29 T 01-11-2018 IPR020258 Uncharacterised protein family YbeF MLA2C4_05920 847d3375e43e906b351f75de0928a32d 221 Pfam PF00395 S-layer homology domain 43 85 4.4E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05920 847d3375e43e906b351f75de0928a32d 221 Pfam PF00395 S-layer homology domain 163 206 5.9E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05920 847d3375e43e906b351f75de0928a32d 221 Pfam PF00395 S-layer homology domain 116 146 4.5E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_07130 205ebc356b5119e0c9d1d7999bd5653c 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 3 57 6.0E-26 T 01-11-2018 IPR018690 Protein of unknown function DUF2187 MLA2C4_26275 cf801ecf997bc4335e9a96e6d087d787 399 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 3.3E-63 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MLA2C4_26275 cf801ecf997bc4335e9a96e6d087d787 399 Gene3D G3DSA:1.20.1530.20 2 386 6.9E-64 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_13140 694cad056ea2d91914545ad58423ad06 40 Pfam PF13106 Domain of unknown function (DUF3961) 2 29 8.7E-13 T 01-11-2018 IPR025081 Domain of unknown function DUF3961 MLA2C4_09025 313f3b4252b6b9ad171b3be066142f28 237 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 13 216 2.2E-55 T 01-11-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MLA2C4_12355 98ebbb459858ef0cfe0d87d4712a5182 141 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 2.4E-28 T 01-11-2018 IPR006750 Putative inner membrane exporter, YdcZ MLA2C4_12240 ede9022997f4941f4e8f7d4198b7a757 255 Pfam PF13030 Protein of unknown function (DUF3891) 1 229 7.3E-64 T 01-11-2018 IPR024992 Protein of unknown function DUF3891 MLA2C4_23795 acff3b8507ee703139e8946486aac255 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.0E-67 T 01-11-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MLA2C4_23795 acff3b8507ee703139e8946486aac255 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 86.645 T 01-11-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MLA2C4_23795 acff3b8507ee703139e8946486aac255 153 Pfam PF03477 ATP cone domain 50 136 1.8E-20 T 01-11-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MLA2C4_17995 2819b6577a301fc67f0221eeb81c81f3 463 Pfam PF00324 Amino acid permease 14 424 1.7E-102 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_17995 2819b6577a301fc67f0221eeb81c81f3 463 Gene3D G3DSA:1.20.1740.10 5 452 5.4E-60 T 01-11-2018 MLA2C4_17995 2819b6577a301fc67f0221eeb81c81f3 463 PIRSF PIRSF006060 2 461 2.1E-67 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_17995 2819b6577a301fc67f0221eeb81c81f3 463 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_09395 527d2fb5bd6ccbe67b3d954b9284683f 213 Gene3D G3DSA:1.20.1280.250 1 84 2.9E-13 T 01-11-2018 IPR038344 EF-G binding protein, N-terminal domain superfamily MLA2C4_09395 527d2fb5bd6ccbe67b3d954b9284683f 213 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 86 1.7E-27 T 01-11-2018 IPR010841 Elongation factor G-binding protein, N-terminal MLA2C4_09395 527d2fb5bd6ccbe67b3d954b9284683f 213 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 99 204 2.1E-10 T 01-11-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 Pfam PF01555 DNA methylase 113 444 4.9E-36 T 01-11-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 SUPERFAMILY SSF53335 81 465 4.53E-51 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 113 125 4.6E-9 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 410 424 4.6E-9 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 176 195 4.6E-9 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 01-11-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MLA2C4_06770 1d8d9e17a11ffe51e3a1fe2c554cef9b 641 PIRSF PIRSF015855 1 634 1.5E-160 T 01-11-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 MLA2C4_24930 ee7b3fbe3053fb4fc480ed6b9a37a323 76 Pfam PF13129 Protein of unknown function (DUF3953) 32 72 2.8E-10 T 01-11-2018 IPR025018 Protein of unknown function DUF3953 MLA2C4_11155 ab21a6e4250076aacb72e74259b12199 195 Pfam PF14005 YpjP-like protein 62 193 1.1E-60 T 01-11-2018 IPR025616 YpjP-like protein MLA2C4_16050 650b8635668268449e3acb71e2159377 104 Pfam PF13031 Protein of unknown function (DUF3892) 35 102 1.4E-15 T 01-11-2018 IPR024997 Protein of unknown function DUF3892 MLA2C4_13250 029f9037a45870bed0e6f90627bf7347 240 Pfam PF13649 Methyltransferase domain 63 156 1.2E-17 T 01-11-2018 MLA2C4_13250 029f9037a45870bed0e6f90627bf7347 240 Gene3D G3DSA:3.40.50.150 53 223 5.8E-38 T 01-11-2018 MLA2C4_13250 029f9037a45870bed0e6f90627bf7347 240 SUPERFAMILY SSF53335 25 220 7.6E-40 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_24300 8d00624ff7f37a5261f0be25b7bb24d2 120 Pfam PF14119 Domain of unknown function (DUF4288) 1 97 8.0E-30 T 01-11-2018 IPR025630 Protein of unknown function DUF4288 MLA2C4_07590 9cd47ca764adea1ab7bcbd49b8d76aab 246 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 131 243 1.2E-34 T 01-11-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF MLA2C4_07590 9cd47ca764adea1ab7bcbd49b8d76aab 246 PIRSF PIRSF031509 5 246 5.7E-74 T 01-11-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 MLA2C4_20835 9687d8553fbc30dbfd63b8d2167d1482 78 SUPERFAMILY SSF143567 2 77 1.16E-27 T 01-11-2018 IPR038073 YkuJ-like superfamily MLA2C4_20835 9687d8553fbc30dbfd63b8d2167d1482 78 PIRSF PIRSF037356 1 78 5.7E-36 T 01-11-2018 IPR014904 Protein of unknown function DUF1797 MLA2C4_20835 9687d8553fbc30dbfd63b8d2167d1482 78 Pfam PF08796 Protein of unknown function (DUF1797) 7 77 2.0E-27 T 01-11-2018 IPR014904 Protein of unknown function DUF1797 MLA2C4_20835 9687d8553fbc30dbfd63b8d2167d1482 78 Gene3D G3DSA:3.30.720.20 1 78 1.3E-33 T 01-11-2018 IPR038073 YkuJ-like superfamily MLA2C4_08260 2af70b758f3a631402d3a451df7d3fe0 90 Pfam PF10752 Protein of unknown function (DUF2533) 1 83 1.0E-37 T 01-11-2018 IPR019688 Protein of unknown function DUF2533 MLA2C4_27315 fc687bb2af43e137813732df4c003ea5 225 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 25 225 3.2E-70 T 01-11-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MLA2C4_27315 fc687bb2af43e137813732df4c003ea5 225 Gene3D G3DSA:3.40.50.300 2 225 2.4E-75 T 01-11-2018 MLA2C4_27315 fc687bb2af43e137813732df4c003ea5 225 SUPERFAMILY SSF52540 44 218 3.27E-39 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_27315 fc687bb2af43e137813732df4c003ea5 225 Pfam PF13614 AAA domain 46 187 9.2E-13 T 01-11-2018 IPR025669 AAA domain MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 Gene3D G3DSA:3.30.870.10 46 238 2.8E-34 T 01-11-2018 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 SUPERFAMILY SSF56024 48 220 4.04E-36 T 01-11-2018 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 Gene3D G3DSA:3.30.870.10 239 385 1.3E-24 T 01-11-2018 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 Pfam PF13091 PLD-like domain 250 366 6.8E-26 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 Pfam PF13091 PLD-like domain 69 210 2.2E-8 T 01-11-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 SUPERFAMILY SSF56024 247 389 4.26E-31 T 01-11-2018 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 SMART SM00155 321 348 0.0012 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_16705 c2552709f0e908cf7ced458ac69f1c1b 408 SMART SM00155 150 177 0.16 T 01-11-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MLA2C4_04735 644115cd7fcf4decdc93064ecc1deaa6 289 Gene3D G3DSA:3.30.1240.10 83 196 5.5E-69 T 01-11-2018 MLA2C4_04735 644115cd7fcf4decdc93064ecc1deaa6 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 241 3.1E-17 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_04735 644115cd7fcf4decdc93064ecc1deaa6 289 Gene3D G3DSA:3.40.50.1000 5 264 5.5E-69 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_04735 644115cd7fcf4decdc93064ecc1deaa6 289 SUPERFAMILY SSF56784 2 273 1.29E-51 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_04735 644115cd7fcf4decdc93064ecc1deaa6 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 268 4.0E-47 T 01-11-2018 MLA2C4_06325 2312e036fa0ef2621f96fa71c8c9abcb 246 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 246 63.56 T 01-11-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 MLA2C4_06325 2312e036fa0ef2621f96fa71c8c9abcb 246 Gene3D G3DSA:3.60.21.10 1 238 2.3E-62 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_06325 2312e036fa0ef2621f96fa71c8c9abcb 246 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 6.6E-14 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_06325 2312e036fa0ef2621f96fa71c8c9abcb 246 SUPERFAMILY SSF56300 1 220 6.04E-40 T 01-11-2018 MLA2C4_15870 40caa353ed71c4a9f8a5bda733c3e7aa 388 Pfam PF01882 Protein of unknown function DUF58 213 292 2.8E-12 T 01-11-2018 IPR002881 Domain of unknown function DUF58 MLA2C4_21050 2784ab43c2db92318f9abc6adc260197 97 Pfam PF13065 Protein of unknown function (DUF3928) 1 95 3.5E-64 T 01-11-2018 IPR025170 Protein of unknown function DUF3928 MLA2C4_06550 2d7ea7b4b7dba8fc0936909f34531efd 142 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 86 - T 01-11-2018 IPR010916 TonB box, conserved site MLA2C4_04355 411490acbd73fafddde30b52ec846460 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 1.5E-18 T 01-11-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MLA2C4_04355 411490acbd73fafddde30b52ec846460 101 SUPERFAMILY SSF52794 1 98 9.16E-32 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_04355 411490acbd73fafddde30b52ec846460 101 Gene3D G3DSA:3.40.50.2300 1 101 1.8E-32 T 01-11-2018 MLA2C4_15270 7e6bb5785efdcb5db76144e85618a1e5 222 Pfam PF14172 Domain of unknown function (DUF4309) 85 211 2.3E-42 T 01-11-2018 IPR025453 Protein of unknown function DUF4309 MLA2C4_26050 4d4a2023875190668e7d8196fd062398 279 Gene3D G3DSA:3.40.710.10 19 279 2.3E-70 T 01-11-2018 MLA2C4_26050 4d4a2023875190668e7d8196fd062398 279 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 257 4.3E-47 T 01-11-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MLA2C4_26050 4d4a2023875190668e7d8196fd062398 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 1.6E-8 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_26050 4d4a2023875190668e7d8196fd062398 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 132 1.6E-8 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_26050 4d4a2023875190668e7d8196fd062398 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.6E-8 T 01-11-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MLA2C4_26050 4d4a2023875190668e7d8196fd062398 279 SUPERFAMILY SSF56601 7 277 9.39E-53 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_28015 42b6d3e15ec287b5a7bf9b50199186a3 409 Gene3D G3DSA:1.10.3080.10 1 401 1.6E-30 T 01-11-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MLA2C4_28015 42b6d3e15ec287b5a7bf9b50199186a3 409 SUPERFAMILY SSF81340 8 399 8.24E-51 T 01-11-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MLA2C4_28015 42b6d3e15ec287b5a7bf9b50199186a3 409 Pfam PF00654 Voltage gated chloride channel 62 398 3.6E-41 T 01-11-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MLA2C4_14660 cb3ba91142f7e6cb226299f2cb6c23e8 183 Pfam PF00583 Acetyltransferase (GNAT) family 65 153 1.1E-15 T 01-11-2018 IPR000182 GNAT domain MLA2C4_14660 cb3ba91142f7e6cb226299f2cb6c23e8 183 Gene3D G3DSA:3.40.630.30 15 181 5.9E-37 T 01-11-2018 MLA2C4_14660 cb3ba91142f7e6cb226299f2cb6c23e8 183 SUPERFAMILY SSF55729 15 182 1.46E-28 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 SUPERFAMILY SSF51735 1 318 1.77E-83 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 242 2.2E-59 T 01-11-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 PRINTS PR01713 Nucleotide sugar epimerase signature 35 51 8.8E-5 T 01-11-2018 MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 PRINTS PR01713 Nucleotide sugar epimerase signature 236 251 8.8E-5 T 01-11-2018 MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 PRINTS PR01713 Nucleotide sugar epimerase signature 281 298 8.8E-5 T 01-11-2018 MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 PRINTS PR01713 Nucleotide sugar epimerase signature 214 229 8.8E-5 T 01-11-2018 MLA2C4_02635 ba3dabd57b7152f9142e725b0d407a32 321 Gene3D G3DSA:3.40.50.720 2 320 4.1E-100 T 01-11-2018 MLA2C4_01185 2a55c05ecaea61cbe4a85192e9d28368 31 Pfam PF13134 Protein of unknown function (DUF3948) 1 26 5.2E-12 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_09420 9ac5531d69fca6edc737e88278716eab 412 SUPERFAMILY SSF81296 25 120 1.19E-20 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_09420 9ac5531d69fca6edc737e88278716eab 412 Pfam PF04234 CopC domain 26 120 3.0E-21 T 01-11-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MLA2C4_09420 9ac5531d69fca6edc737e88278716eab 412 Gene3D G3DSA:2.60.40.1220 26 126 8.7E-25 T 01-11-2018 MLA2C4_18875 159ff8a0b76d72423cd7a8deace4816a 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 520 1.6E-17 T 01-11-2018 IPR025110 AMP-binding enzyme, C-terminal domain MLA2C4_18875 159ff8a0b76d72423cd7a8deace4816a 537 Gene3D G3DSA:3.40.50.12780 1 431 6.3E-121 T 01-11-2018 MLA2C4_18875 159ff8a0b76d72423cd7a8deace4816a 537 SUPERFAMILY SSF56801 7 532 1.44E-134 T 01-11-2018 MLA2C4_18875 159ff8a0b76d72423cd7a8deace4816a 537 Pfam PF00501 AMP-binding enzyme 23 436 1.3E-93 T 01-11-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MLA2C4_18875 159ff8a0b76d72423cd7a8deace4816a 537 Gene3D G3DSA:3.30.300.310 432 535 5.7E-34 T 01-11-2018 MLA2C4_24935 6125c1de5cf4a24c0c9de3891705759f 77 Pfam PF13129 Protein of unknown function (DUF3953) 32 72 7.8E-6 T 01-11-2018 IPR025018 Protein of unknown function DUF3953 MLA2C4_24920 491a5967561910806fd085a514c1873b 49 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 1 44 1.1E-17 T 01-11-2018 IPR022248 TNF receptor family, RELT MLA2C4_03560 536f0cfc58dd8646f6f90f4f8608e387 114 SUPERFAMILY SSF81324 5 106 1.83E-23 T 01-11-2018 MLA2C4_03560 536f0cfc58dd8646f6f90f4f8608e387 114 Gene3D G3DSA:1.10.287.70 1 114 6.2E-50 T 01-11-2018 MLA2C4_03560 536f0cfc58dd8646f6f90f4f8608e387 114 Pfam PF07885 Ion channel 30 99 1.0E-20 T 01-11-2018 IPR013099 Potassium channel domain MLA2C4_16540 bca1bf86783da7f708de9fc9652c40d7 272 Pfam PF07423 Protein of unknown function (DUF1510) 5 117 2.3E-12 T 01-11-2018 IPR009988 Protein of unknown function DUF1510 MLA2C4_16540 bca1bf86783da7f708de9fc9652c40d7 272 Pfam PF07423 Protein of unknown function (DUF1510) 99 271 8.8E-47 T 01-11-2018 IPR009988 Protein of unknown function DUF1510 MLA2C4_15655 97091b247ba23022fb23607511e53e61 347 Gene3D G3DSA:3.40.50.2300 136 347 3.9E-106 T 01-11-2018 MLA2C4_15655 97091b247ba23022fb23607511e53e61 347 Pfam PF13407 Periplasmic binding protein domain 36 294 1.1E-54 T 01-11-2018 IPR025997 Periplasmic binding protein MLA2C4_15655 97091b247ba23022fb23607511e53e61 347 SUPERFAMILY SSF53822 34 347 3.0E-80 T 01-11-2018 IPR028082 Periplasmic binding protein-like I MLA2C4_15655 97091b247ba23022fb23607511e53e61 347 Gene3D G3DSA:3.40.50.2300 36 331 3.9E-106 T 01-11-2018 MLA2C4_03655 7ba3be10c85414ddcf5fdb498b46f95e 430 Pfam PF00860 Permease family 13 393 4.0E-47 T 01-11-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_03655 7ba3be10c85414ddcf5fdb498b46f95e 430 PIRSF PIRSF005353 1 430 8.4E-145 T 01-11-2018 IPR026033 Purine permease PbuG-like MLA2C4_23625 f5e825df7ae109d7aa95b5f90b5b92eb 293 Pfam PF01497 Periplasmic binding protein 41 269 2.4E-42 T 01-11-2018 IPR002491 ABC transporter periplasmic binding domain MLA2C4_23625 f5e825df7ae109d7aa95b5f90b5b92eb 293 SUPERFAMILY SSF53807 38 293 1.33E-53 T 01-11-2018 MLA2C4_23625 f5e825df7ae109d7aa95b5f90b5b92eb 293 Gene3D G3DSA:3.40.50.1980 123 293 2.0E-59 T 01-11-2018 MLA2C4_23625 f5e825df7ae109d7aa95b5f90b5b92eb 293 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 4 292 4.5E-135 T 01-11-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 MLA2C4_23625 f5e825df7ae109d7aa95b5f90b5b92eb 293 Gene3D G3DSA:3.40.50.1980 35 122 2.6E-33 T 01-11-2018 MLA2C4_10055 2afb5a3c6ce1dfb0fadb8493b7ccd6d0 273 Gene3D G3DSA:3.20.20.370 25 261 5.6E-65 T 01-11-2018 MLA2C4_10055 2afb5a3c6ce1dfb0fadb8493b7ccd6d0 273 Pfam PF01522 Polysaccharide deacetylase 64 170 7.2E-29 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_10055 2afb5a3c6ce1dfb0fadb8493b7ccd6d0 273 SUPERFAMILY SSF88713 63 264 1.46E-55 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_25000 acae29cd18ec33c6cbc50325efc7b79d 271 Pfam PF14042 Domain of unknown function (DUF4247) 29 210 3.6E-37 T 01-11-2018 IPR025341 Protein of unknown function DUF4247 MLA2C4_10270 f9ed06368db99ce7d2d0539d1d4e1833 63 Pfam PF13035 Protein of unknown function (DUF3896) 1 61 4.5E-39 T 01-11-2018 IPR024994 Protein of unknown function DUF3896 MLA2C4_23010 91d5c7c0b176345bb0ed6e8e0f8891c7 519 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 3.0E-53 T 01-11-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MLA2C4_23010 91d5c7c0b176345bb0ed6e8e0f8891c7 519 PIRSF PIRSF038958 1 517 6.0E-175 T 01-11-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type MLA2C4_23010 91d5c7c0b176345bb0ed6e8e0f8891c7 519 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 359 500 5.6E-17 T 01-11-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MLA2C4_23010 91d5c7c0b176345bb0ed6e8e0f8891c7 519 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 494 1.5E-196 T 01-11-2018 IPR014249 Sporulation stage V protein B MLA2C4_18900 79977cdf4dc518ae4adaf515d16b11b5 83 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 5 78 4.4E-24 T 01-11-2018 IPR018680 Protein of unknown function DUF2164 MLA2C4_27235 9f15f377bac2c1b1ed07d12a35f76512 304 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 220 3.4E-52 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_27235 9f15f377bac2c1b1ed07d12a35f76512 304 Hamap MF_01140 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU [tagU]. 2 302 48.632 T 01-11-2018 IPR023734 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU MLA2C4_27235 9f15f377bac2c1b1ed07d12a35f76512 304 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 78 219 2.2E-51 T 01-11-2018 IPR004474 Cell envelope-related transcriptional attenuator domain MLA2C4_27235 9f15f377bac2c1b1ed07d12a35f76512 304 Gene3D G3DSA:1.10.260.150 42 304 1.6E-91 T 01-11-2018 MLA2C4_13135 917b02c3809dd50a71c73f1c2fe3059c 88 Gene3D G3DSA:1.10.260.40 9 71 1.0E-8 T 01-11-2018 MLA2C4_13135 917b02c3809dd50a71c73f1c2fe3059c 88 SUPERFAMILY SSF47413 13 67 7.39E-9 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_13135 917b02c3809dd50a71c73f1c2fe3059c 88 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 17 66 2.3E-7 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_13135 917b02c3809dd50a71c73f1c2fe3059c 88 SMART SM00530 16 72 0.0018 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 SMART SM00028 165 198 250.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 SMART SM00028 33 67 24.0 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 SMART SM00028 68 101 0.0035 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 Pfam PF13181 Tetratricopeptide repeat 170 191 0.2 T 01-11-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 Pfam PF09295 ChAPs (Chs5p-Arf1p-binding proteins) 18 91 1.1E-5 T 01-11-2018 IPR015374 Chs5p-Arf1p binding MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 Gene3D G3DSA:1.25.40.10 1 199 1.0E-32 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_17625 83270ab239c76b30ecd6c242d8a90506 304 SUPERFAMILY SSF48452 4 192 4.93E-26 T 01-11-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MLA2C4_22380 aac07e730e99c3b9e807a778521c0487 256 SUPERFAMILY SSF52540 2 227 1.91E-59 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_22380 aac07e730e99c3b9e807a778521c0487 256 SMART SM00382 29 214 8.8E-15 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_22380 aac07e730e99c3b9e807a778521c0487 256 Gene3D G3DSA:3.40.50.300 1 250 5.8E-66 T 01-11-2018 MLA2C4_22380 aac07e730e99c3b9e807a778521c0487 256 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_22380 aac07e730e99c3b9e807a778521c0487 256 Pfam PF00005 ABC transporter 20 168 1.4E-33 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 Gene3D G3DSA:3.40.50.1000 6 260 2.1E-62 T 01-11-2018 IPR023214 HAD superfamily MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 3.7E-28 T 01-11-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 1.0E-65 T 01-11-2018 MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 01-11-2018 MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 1.1E-56 T 01-11-2018 IPR000150 Cof family GO:0016787 MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 Gene3D G3DSA:3.30.1240.10 86 191 2.1E-62 T 01-11-2018 MLA2C4_06145 cf3eabc06d15982e386b225f3d98388d 269 SUPERFAMILY SSF56784 2 267 6.36E-68 T 01-11-2018 IPR036412 HAD-like superfamily MLA2C4_22070 9184c7de9300d07a6b18cf008ecd9c90 207 Pfam PF13346 ABC-2 family transporter protein 4 202 3.9E-32 T 01-11-2018 IPR025699 ABC-2 membrane transporter-like MLA2C4_00295 0f6949ed4f8683654223dc31a63d8ab3 74 ProDom PD057826 YABK 1 74 4.0E-36 T 01-11-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 MLA2C4_00295 0f6949ed4f8683654223dc31a63d8ab3 74 Pfam PF10955 Protein of unknown function (DUF2757) 1 74 1.0E-28 T 01-11-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 MLA2C4_25885 72d6b3882c1e4067a99246cedf2b6bc1 243 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 138 227 1.8E-29 T 01-11-2018 IPR014197 Sporulation protein YunB MLA2C4_25885 72d6b3882c1e4067a99246cedf2b6bc1 243 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 17 231 3.9E-82 T 01-11-2018 IPR014197 Sporulation protein YunB MLA2C4_25885 72d6b3882c1e4067a99246cedf2b6bc1 243 PIRSF PIRSF021383 3 236 6.3E-65 T 01-11-2018 IPR014197 Sporulation protein YunB MLA2C4_17480 6bb9a2a4d2f57ab77b2c110419b261c4 119 Pfam PF12676 Protein of unknown function (DUF3796) 4 114 4.1E-33 T 01-11-2018 IPR024257 Protein of unknown function DUF3796 MLA2C4_03480 7c05a02fd86fae782ab401448d892d67 308 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 01-11-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MLA2C4_03480 7c05a02fd86fae782ab401448d892d67 308 Gene3D G3DSA:3.40.50.300 1 306 6.2E-92 T 01-11-2018 MLA2C4_03480 7c05a02fd86fae782ab401448d892d67 308 SUPERFAMILY SSF52540 3 253 3.79E-76 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_03480 7c05a02fd86fae782ab401448d892d67 308 Pfam PF00005 ABC transporter 31 181 3.4E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_03480 7c05a02fd86fae782ab401448d892d67 308 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 277 8.2E-8 T 01-11-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MLA2C4_03480 7c05a02fd86fae782ab401448d892d67 308 SMART SM00382 39 238 5.0E-14 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_17985 a4434fcf59b21aa27adef301936823db 250 Gene3D G3DSA:3.60.15.10 1 241 1.7E-98 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_17985 a4434fcf59b21aa27adef301936823db 250 SUPERFAMILY SSF56281 24 236 3.8E-38 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_17985 a4434fcf59b21aa27adef301936823db 250 Pfam PF00753 Metallo-beta-lactamase superfamily 33 235 8.7E-32 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_17985 a4434fcf59b21aa27adef301936823db 250 SMART SM00849 34 235 2.6E-26 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_28105 95acbddb9ef3c73d924fd22f6ce7b24d 437 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 129 272 1.7E-8 T 01-11-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MLA2C4_05115 df3c1970b2e0f494f7db3357d62121fb 152 SMART SM00347 26 126 1.4E-8 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_05115 df3c1970b2e0f494f7db3357d62121fb 152 SUPERFAMILY SSF46785 6 142 1.95E-22 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_05115 df3c1970b2e0f494f7db3357d62121fb 152 Gene3D G3DSA:1.10.10.10 1 144 6.6E-26 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_05115 df3c1970b2e0f494f7db3357d62121fb 152 Pfam PF12802 MarR family 32 90 3.8E-10 T 01-11-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MLA2C4_10120 28baccb5c0c4e362ee230d9e28eb67d2 204 Pfam PF01810 LysE type translocator 15 200 2.0E-29 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_14990 2e7a386fa61653e0fa6875a581f88c1e 345 PIRSF PIRSF029792 1 334 1.9E-140 T 01-11-2018 IPR008794 Proline racemase family MLA2C4_14990 2e7a386fa61653e0fa6875a581f88c1e 345 SUPERFAMILY SSF54506 1 331 6.42E-114 T 01-11-2018 MLA2C4_14990 2e7a386fa61653e0fa6875a581f88c1e 345 Pfam PF05544 Proline racemase 10 331 5.9E-117 T 01-11-2018 IPR008794 Proline racemase family MLA2C4_14990 2e7a386fa61653e0fa6875a581f88c1e 345 Gene3D G3DSA:3.10.310.10 7 333 2.6E-123 T 01-11-2018 MLA2C4_14990 2e7a386fa61653e0fa6875a581f88c1e 345 Gene3D G3DSA:3.10.310.10 146 310 2.6E-123 T 01-11-2018 MLA2C4_24775 e5eb872b493ccfaabf0c8da8d5fbe326 170 Gene3D G3DSA:2.160.10.10 1 170 1.8E-75 T 01-11-2018 MLA2C4_24775 e5eb872b493ccfaabf0c8da8d5fbe326 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 5.2E-8 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_24775 e5eb872b493ccfaabf0c8da8d5fbe326 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 44 1.1E-4 T 01-11-2018 IPR001451 Hexapeptide repeat MLA2C4_24775 e5eb872b493ccfaabf0c8da8d5fbe326 170 SUPERFAMILY SSF51161 2 168 3.05E-51 T 01-11-2018 IPR011004 Trimeric LpxA-like superfamily MLA2C4_19970 a435150b7a9b19418d51a6879cf43455 418 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 417 2.3E-112 T 01-11-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MLA2C4_19970 a435150b7a9b19418d51a6879cf43455 418 Pfam PF13180 PDZ domain 200 265 6.1E-9 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_19970 a435150b7a9b19418d51a6879cf43455 418 Gene3D G3DSA:2.30.42.10 199 287 2.4E-23 T 01-11-2018 MLA2C4_19970 a435150b7a9b19418d51a6879cf43455 418 SUPERFAMILY SSF50156 172 266 1.58E-19 T 01-11-2018 IPR036034 PDZ superfamily GO:0005515 MLA2C4_19970 a435150b7a9b19418d51a6879cf43455 418 Pfam PF02163 Peptidase family M50 6 404 3.8E-82 T 01-11-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MLA2C4_19970 a435150b7a9b19418d51a6879cf43455 418 SMART SM00228 183 257 2.0E-8 T 01-11-2018 IPR001478 PDZ domain GO:0005515 MLA2C4_02735 f10e5606e98b0cd050fa967392b2f283 176 PIRSF PIRSF028345 1 176 2.5E-80 T 01-11-2018 IPR016882 Uncharacterised protein family UPF0374 MLA2C4_02735 f10e5606e98b0cd050fa967392b2f283 176 Gene3D G3DSA:2.40.380.10 19 169 1.9E-11 T 01-11-2018 IPR035930 FomD-like superfamily MLA2C4_02735 f10e5606e98b0cd050fa967392b2f283 176 Hamap MF_01568 UPF0374 protein . 1 175 51.774 T 01-11-2018 IPR016882 Uncharacterised protein family UPF0374 MLA2C4_02735 f10e5606e98b0cd050fa967392b2f283 176 SUPERFAMILY SSF159234 3 171 4.05E-31 T 01-11-2018 IPR035930 FomD-like superfamily MLA2C4_02735 f10e5606e98b0cd050fa967392b2f283 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 6.9E-17 T 01-11-2018 IPR007295 Domain of unknown function DUF402 MLA2C4_10475 d5c996005f77e0b823f942b56e81da60 165 Pfam PF00583 Acetyltransferase (GNAT) family 36 138 3.5E-17 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10475 d5c996005f77e0b823f942b56e81da60 165 SUPERFAMILY SSF55729 2 164 1.51E-35 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_10475 d5c996005f77e0b823f942b56e81da60 165 Gene3D G3DSA:3.40.630.30 1 165 9.8E-42 T 01-11-2018 MLA2C4_06925 f0b7ae089edab054c10601743fcb4d63 239 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 63.005 T 01-11-2018 IPR022822 Lactate utilization protein A GO:0006089 MLA2C4_06925 f0b7ae089edab054c10601743fcb4d63 239 Pfam PF02754 Cysteine-rich domain 3 83 3.7E-18 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_06925 f0b7ae089edab054c10601743fcb4d63 239 Pfam PF02754 Cysteine-rich domain 132 215 5.7E-16 T 01-11-2018 IPR004017 Cysteine-rich domain MLA2C4_05015 2bf775c3eeb9a6f3fe65abe9ccb1cb0c 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 247 6.3E-42 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MLA2C4_21580 1e9fc6e7d0b076e5f444956a5b02d7d8 259 SUPERFAMILY SSF52266 56 254 4.65E-29 T 01-11-2018 MLA2C4_21580 1e9fc6e7d0b076e5f444956a5b02d7d8 259 Gene3D G3DSA:3.40.50.1110 19 255 2.4E-29 T 01-11-2018 IPR036514 SGNH hydrolase superfamily MLA2C4_21580 1e9fc6e7d0b076e5f444956a5b02d7d8 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 57 245 2.8E-19 T 01-11-2018 IPR013830 SGNH hydrolase-type esterase domain MLA2C4_24005 1fbdedcd9dc730348d03df43b87c9ccc 110 SUPERFAMILY SSF51182 1 98 2.07E-18 T 01-11-2018 IPR011051 RmlC-like cupin domain superfamily MLA2C4_24005 1fbdedcd9dc730348d03df43b87c9ccc 110 Pfam PF07883 Cupin domain 40 88 6.3E-14 T 01-11-2018 IPR013096 Cupin 2, conserved barrel MLA2C4_24005 1fbdedcd9dc730348d03df43b87c9ccc 110 Gene3D G3DSA:2.60.120.10 1 103 4.9E-27 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_22900 1c807fb1b951e8449e044301b19e7365 355 Pfam PF01594 AI-2E family transporter 33 345 5.2E-68 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like MLA2C4_15765 4e30a4bd1ef8178615c340cf436b367b 474 Gene3D G3DSA:1.20.1740.10 9 473 2.5E-64 T 01-11-2018 MLA2C4_15765 4e30a4bd1ef8178615c340cf436b367b 474 Pfam PF00324 Amino acid permease 19 463 1.9E-129 T 01-11-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 MLA2C4_15765 4e30a4bd1ef8178615c340cf436b367b 474 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 01-11-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MLA2C4_15765 4e30a4bd1ef8178615c340cf436b367b 474 PIRSF PIRSF006060 1 473 1.6E-73 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_14945 52a880b077465c885f6811dafea065b3 221 SUPERFAMILY SSF81296 35 201 1.02E-60 T 01-11-2018 IPR014756 Immunoglobulin E-set MLA2C4_14945 52a880b077465c885f6811dafea065b3 221 Gene3D G3DSA:2.70.50.50 35 201 1.0E-67 T 01-11-2018 MLA2C4_14945 52a880b077465c885f6811dafea065b3 221 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 35 198 4.0E-37 T 01-11-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal MLA2C4_03980 42195068b810f0afa6492d81d8c2dc0c 34 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 8 30 1.2E-4 T 01-11-2018 IPR023833 Signal peptide, camelysin MLA2C4_19995 8e1b076c839d7ff09573de440ab5b2a7 240 Pfam PF00696 Amino acid kinase family 7 217 3.9E-29 T 01-11-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MLA2C4_19995 8e1b076c839d7ff09573de440ab5b2a7 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 5.2E-102 T 01-11-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MLA2C4_19995 8e1b076c839d7ff09573de440ab5b2a7 240 PIRSF PIRSF005650 1 240 5.9E-98 T 01-11-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MLA2C4_19995 8e1b076c839d7ff09573de440ab5b2a7 240 Gene3D G3DSA:3.40.1160.10 2 239 7.0E-82 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_19995 8e1b076c839d7ff09573de440ab5b2a7 240 SUPERFAMILY SSF53633 4 238 4.19E-74 T 01-11-2018 IPR036393 Acetylglutamate kinase-like superfamily MLA2C4_19995 8e1b076c839d7ff09573de440ab5b2a7 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 44.84 T 01-11-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MLA2C4_03220 1e8f1d08f46cec8f986a8b49dcf0b48c 539 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 532 6.1E-184 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MLA2C4_03220 1e8f1d08f46cec8f986a8b49dcf0b48c 539 Pfam PF02652 L-lactate permease 16 530 8.0E-177 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MLA2C4_05250 6014fc5b025e3f5e20db722902373768 318 SUPERFAMILY SSF56059 85 288 2.09E-22 T 01-11-2018 MLA2C4_05250 6014fc5b025e3f5e20db722902373768 318 Pfam PF08443 RimK-like ATP-grasp domain 96 207 1.6E-7 T 01-11-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MLA2C4_05250 6014fc5b025e3f5e20db722902373768 318 Gene3D G3DSA:3.30.1490.20 111 180 9.8E-7 T 01-11-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MLA2C4_18670 683df1253d0aa21db801f13dfb341a28 131 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 49 128 2.0E-5 T 01-11-2018 MLA2C4_23445 2bba8d488f6e552e59d2655830a685f2 408 Pfam PF12698 ABC-2 family transporter protein 19 377 6.1E-43 T 01-11-2018 MLA2C4_08395 680b673fda2b39d131ca544f9ef5e6ff 113 Pfam PF04341 Protein of unknown function, DUF485 22 105 9.0E-23 T 01-11-2018 IPR007436 Protein of unknown function DUF485 MLA2C4_27400 2cffca0b03a8240fbf5ddd5e6794eda2 104 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 104 20.226 T 01-11-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 MLA2C4_27400 2cffca0b03a8240fbf5ddd5e6794eda2 104 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 99 1.3E-24 T 01-11-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like MLA2C4_27450 6a51f3e6693dcea7dae7562077f26ab9 263 Pfam PF06161 Protein of unknown function (DUF975) 4 260 6.8E-32 T 01-11-2018 IPR010380 Protein of unknown function DUF975 MLA2C4_08335 19cc272d87fc54152d439c5c6715ca63 301 SUPERFAMILY SSF103481 196 294 2.35E-16 T 01-11-2018 MLA2C4_08335 19cc272d87fc54152d439c5c6715ca63 301 Pfam PF00892 EamA-like transporter family 149 288 1.3E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_08335 19cc272d87fc54152d439c5c6715ca63 301 Pfam PF00892 EamA-like transporter family 8 140 3.0E-20 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_08335 19cc272d87fc54152d439c5c6715ca63 301 SUPERFAMILY SSF103481 41 143 1.15E-12 T 01-11-2018 MLA2C4_21155 69249a5a0315160f68ba06b24de9377d 205 Gene3D G3DSA:3.40.109.10 1 204 4.8E-51 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_21155 69249a5a0315160f68ba06b24de9377d 205 Pfam PF00881 Nitroreductase family 12 183 6.6E-29 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_21155 69249a5a0315160f68ba06b24de9377d 205 SUPERFAMILY SSF55469 5 203 1.96E-50 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_07935 337db532d176300e3495fe2c562c54ab 237 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 13 237 2.0E-126 T 01-11-2018 MLA2C4_24840 c26cbac9876828792f08c7e13399ba67 107 SUPERFAMILY SSF89360 1 104 3.53E-25 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MLA2C4_24840 c26cbac9876828792f08c7e13399ba67 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 1.7E-23 T 01-11-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MLA2C4_24840 c26cbac9876828792f08c7e13399ba67 107 Gene3D G3DSA:2.60.300.12 1 102 1.0E-6 T 01-11-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MLA2C4_20925 9ff0453465a00283580fb282060ca0a0 143 Gene3D G3DSA:3.90.79.10 3 140 3.1E-31 T 01-11-2018 MLA2C4_20925 9ff0453465a00283580fb282060ca0a0 143 PRINTS PR00502 NUDIX hydrolase family signature 39 53 2.6E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_20925 9ff0453465a00283580fb282060ca0a0 143 PRINTS PR00502 NUDIX hydrolase family signature 53 68 2.6E-8 T 01-11-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MLA2C4_20925 9ff0453465a00283580fb282060ca0a0 143 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 01-11-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MLA2C4_20925 9ff0453465a00283580fb282060ca0a0 143 SUPERFAMILY SSF55811 7 135 4.87E-33 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_20925 9ff0453465a00283580fb282060ca0a0 143 Pfam PF00293 NUDIX domain 15 117 4.8E-20 T 01-11-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MLA2C4_06530 42bc845cb3b1999debdcfcd6f1a82d9d 499 Pfam PF02652 L-lactate permease 1 492 1.4E-60 T 01-11-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MLA2C4_24620 fb21aaefd63c4cb0c62d5909f151c906 364 Pfam PF03845 Spore germination protein 9 326 4.6E-101 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_24620 fb21aaefd63c4cb0c62d5909f151c906 364 Gene3D G3DSA:1.20.1740.10 5 363 1.8E-6 T 01-11-2018 MLA2C4_24620 fb21aaefd63c4cb0c62d5909f151c906 364 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 359 1.4E-49 T 01-11-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 MLA2C4_23420 c7f2836ee260a53da1295ffd620f91df 61 Pfam PF04024 PspC domain 3 59 4.6E-20 T 01-11-2018 IPR007168 Phage shock protein, PspC, N-terminal MLA2C4_00210 b55ac5975bac7f682549384376ea9a56 96 Pfam PF01541 GIY-YIG catalytic domain 5 77 1.3E-15 T 01-11-2018 IPR000305 GIY-YIG endonuclease MLA2C4_00210 b55ac5975bac7f682549384376ea9a56 96 SUPERFAMILY SSF82771 5 77 3.4E-12 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_00210 b55ac5975bac7f682549384376ea9a56 96 Gene3D G3DSA:3.40.1440.10 1 96 1.7E-30 T 01-11-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MLA2C4_13475 1c11c7226e0f72500ad16360908354dd 303 Pfam PF00682 HMGL-like 9 280 7.4E-48 T 01-11-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MLA2C4_13475 1c11c7226e0f72500ad16360908354dd 303 Gene3D G3DSA:3.20.20.70 1 300 3.1E-120 T 01-11-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MLA2C4_13475 1c11c7226e0f72500ad16360908354dd 303 SUPERFAMILY SSF51569 4 293 2.38E-68 T 01-11-2018 MLA2C4_01585 007af4d27b1f5fae467eadf4eaacee78 152 SUPERFAMILY SSF160631 20 149 1.57E-15 T 01-11-2018 MLA2C4_01585 007af4d27b1f5fae467eadf4eaacee78 152 Pfam PF14568 SMI1-KNR4 cell-wall 28 141 6.1E-9 T 01-11-2018 MLA2C4_01585 007af4d27b1f5fae467eadf4eaacee78 152 Gene3D G3DSA:3.40.1580.10 15 150 9.2E-10 T 01-11-2018 IPR037883 Knr4/Smi1-like domain superfamily MLA2C4_01585 007af4d27b1f5fae467eadf4eaacee78 152 SMART SM00860 25 143 0.0017 T 01-11-2018 IPR018958 Knr4/Smi1-like domain MLA2C4_18635 f89adad8f00de2fd3a9ab618914fc1b9 268 Pfam PF12679 ABC-2 family transporter protein 28 266 1.1E-12 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_13380 73d609b3955d740671bdd51275fa3ee4 400 Gene3D G3DSA:1.20.1250.20 3 179 8.3E-17 T 01-11-2018 MLA2C4_13380 73d609b3955d740671bdd51275fa3ee4 400 Pfam PF07690 Major Facilitator Superfamily 10 346 7.9E-21 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_13380 73d609b3955d740671bdd51275fa3ee4 400 SUPERFAMILY SSF103473 2 381 9.55E-33 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_13380 73d609b3955d740671bdd51275fa3ee4 400 Gene3D G3DSA:1.20.1250.20 203 380 2.0E-16 T 01-11-2018 MLA2C4_09360 8e8cdd084bab456a4adb45f3b9360efd 170 Pfam PF13302 Acetyltransferase (GNAT) domain 35 147 5.3E-11 T 01-11-2018 IPR000182 GNAT domain MLA2C4_09360 8e8cdd084bab456a4adb45f3b9360efd 170 Gene3D G3DSA:3.40.630.30 9 149 3.9E-23 T 01-11-2018 MLA2C4_09360 8e8cdd084bab456a4adb45f3b9360efd 170 SUPERFAMILY SSF55729 29 155 1.03E-18 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_13385 87c01fb99e9d21f6e5a384bc1467d225 185 Gene3D G3DSA:1.10.357.10 15 169 2.1E-8 T 01-11-2018 MLA2C4_10380 fe08754739140c0ec14fe09c747e6ba6 298 Pfam PF03773 Predicted permease 11 293 2.1E-79 T 01-11-2018 IPR005524 Predicted permease DUF318 MLA2C4_19790 d5ebca43c4ec5c88e37652cf65bbed93 261 PIRSF PIRSF021288 1 260 1.2E-142 T 01-11-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain MLA2C4_19790 d5ebca43c4ec5c88e37652cf65bbed93 261 Pfam PF11868 Protein of unknown function (DUF3388) 70 259 5.0E-107 T 01-11-2018 IPR024514 Domain of unknown function DUF3388 MLA2C4_19790 d5ebca43c4ec5c88e37652cf65bbed93 261 SUPERFAMILY SSF55021 3 73 4.58E-9 T 01-11-2018 MLA2C4_19790 d5ebca43c4ec5c88e37652cf65bbed93 261 Gene3D G3DSA:3.30.70.260 8 73 2.2E-5 T 01-11-2018 MLA2C4_18460 e50f9e5a15a99a3d9c21479a8a872b20 49 Pfam PF14151 YfhD-like protein 3 45 2.6E-19 T 01-11-2018 IPR025435 YfhD-like protein MLA2C4_15005 5a9ad5bfb3c8a66b20000ed853912e9d 90 Gene3D G3DSA:1.10.10.1100 1 69 4.3E-16 T 01-11-2018 MLA2C4_15005 5a9ad5bfb3c8a66b20000ed853912e9d 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 8 59 2.4E-12 T 01-11-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MLA2C4_21165 3aab19552fd3cb63f9356b3d442747d3 122 Pfam PF13054 Protein of unknown function (DUF3915) 1 120 4.8E-67 T 01-11-2018 IPR025026 Protein of unknown function DUF3915 MLA2C4_19795 28972a03b1bde9454b9d8d10136932c7 82 PIRSF PIRSF004764 1 82 5.3E-24 T 01-11-2018 IPR024702 Uncharacterised conserved protein YmfJ MLA2C4_19795 28972a03b1bde9454b9d8d10136932c7 82 Gene3D G3DSA:1.10.760.20 1 82 3.4E-30 T 01-11-2018 IPR038292 YmfJ/YflH superfamily MLA2C4_19795 28972a03b1bde9454b9d8d10136932c7 82 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 1.5E-32 T 01-11-2018 IPR021637 Protein of unknown function DUF3243 MLA2C4_19490 75c9b883143f69c82c08751ebdb4cc18 100 Pfam PF02583 Metal-sensitive transcriptional repressor 16 95 2.4E-32 T 01-11-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MLA2C4_19490 75c9b883143f69c82c08751ebdb4cc18 100 Gene3D G3DSA:1.20.58.1000 1 99 6.5E-38 T 01-11-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily MLA2C4_15415 1722dbeed81d2fcdc7142ca0bfaf94b0 361 Pfam PF01594 AI-2E family transporter 17 348 1.6E-84 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like MLA2C4_20830 b7d5bf0a71c5e6a7e5ad5efb583f532c 172 Pfam PF04308 Ribonuclease H-like 20 172 2.0E-48 T 01-11-2018 IPR007405 Bacteriophage KVP40, Orf299 MLA2C4_14985 01eb4d14a77cceb81ea633df94583e62 313 PIRSF PIRSF029792 1 313 1.1E-83 T 01-11-2018 IPR008794 Proline racemase family MLA2C4_14985 01eb4d14a77cceb81ea633df94583e62 313 SUPERFAMILY SSF54506 1 310 3.45E-59 T 01-11-2018 MLA2C4_14985 01eb4d14a77cceb81ea633df94583e62 313 Gene3D G3DSA:3.10.310.10 144 289 2.5E-49 T 01-11-2018 MLA2C4_14985 01eb4d14a77cceb81ea633df94583e62 313 Gene3D G3DSA:3.10.310.10 8 312 2.5E-49 T 01-11-2018 MLA2C4_14985 01eb4d14a77cceb81ea633df94583e62 313 Pfam PF05544 Proline racemase 10 310 6.6E-29 T 01-11-2018 IPR008794 Proline racemase family MLA2C4_28135 f473f345629ef2e8d78734ba6b95666e 486 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 130 292 7.9E-9 T 01-11-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MLA2C4_16985 fa684bd1b0a7b6d5ba1dcd57559d746c 274 Pfam PF02517 CAAX protease self-immunity 123 225 5.5E-13 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 2.3E-12 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 2.3E-12 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 2.3E-12 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 4.5E-25 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 Pfam PF00209 Sodium:neurotransmitter symporter family 136 441 9.1E-29 T 01-11-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MLA2C4_11090 6cdcf6f000fc3068202bd9c6022769bf 446 SUPERFAMILY SSF161070 5 443 1.14E-130 T 01-11-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MLA2C4_07540 48d6239e7484f44c0538a667c2ca092c 251 Pfam PF01903 CbiX 133 232 1.5E-19 T 01-11-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MLA2C4_07540 48d6239e7484f44c0538a667c2ca092c 251 Pfam PF01903 CbiX 9 112 2.2E-26 T 01-11-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MLA2C4_07540 48d6239e7484f44c0538a667c2ca092c 251 Gene3D G3DSA:3.40.50.1400 123 240 2.5E-18 T 01-11-2018 MLA2C4_07540 48d6239e7484f44c0538a667c2ca092c 251 Gene3D G3DSA:3.40.50.1400 1 114 6.8E-22 T 01-11-2018 MLA2C4_07540 48d6239e7484f44c0538a667c2ca092c 251 SUPERFAMILY SSF53800 1 239 3.92E-43 T 01-11-2018 MLA2C4_21645 048180cfb17e53060274ec3843c92076 292 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 289 2.7E-132 T 01-11-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MLA2C4_21645 048180cfb17e53060274ec3843c92076 292 Pfam PF03313 Serine dehydratase alpha chain 14 274 6.4E-72 T 01-11-2018 IPR005130 Serine dehydratase-like, alpha subunit MLA2C4_21430 c11d493d987b79ea7da2a6dd306ba3fe 44 Pfam PF13072 Protein of unknown function (DUF3936) 1 37 2.5E-22 T 01-11-2018 IPR025177 Cell division inhibitor MciZ MLA2C4_13060 1dc66d8117fad98e946e4fe8e05f59fe 125 Pfam PF12363 Phage tail assembly chaperone protein, TAC 9 108 1.6E-9 T 01-11-2018 IPR024410 Phage tail assembly chaperone protein, TAC MLA2C4_23200 2cfefaaeb8b0355892198bd610699e76 181 Pfam PF04093 rod shape-determining protein MreD 7 166 1.2E-24 T 01-11-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MLA2C4_23200 2cfefaaeb8b0355892198bd610699e76 181 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 11 163 1.3E-28 T 01-11-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MLA2C4_16400 8ecf20aeffd543f95d4917ece6c2b7d3 71 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 29 38 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_16400 8ecf20aeffd543f95d4917ece6c2b7d3 71 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 14 69 4.0E-11 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_16400 8ecf20aeffd543f95d4917ece6c2b7d3 71 Gene3D G3DSA:1.10.8.910 14 71 3.0E-14 T 01-11-2018 IPR038300 SASP, alpha/beta-type superfamily MLA2C4_03525 a4bf0ac4e28b659c8211c548e7e18c3e 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 303 1.7E-52 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_10445 55d336369a65349e0211f9770b63b450 448 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 17 423 1.2E-142 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_10445 55d336369a65349e0211f9770b63b450 448 Pfam PF05525 Branched-chain amino acid transport protein 12 436 1.8E-153 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_02410 109a4f0826d1e352b4e123fb3bcac977 194 Pfam PF02342 TerD domain 3 189 1.3E-82 T 01-11-2018 IPR003325 TerD domain MLA2C4_02410 109a4f0826d1e352b4e123fb3bcac977 194 Gene3D G3DSA:2.60.60.30 20 188 1.7E-70 T 01-11-2018 MLA2C4_17645 6f74f57fb7fe6dee8e29d9f9ae01f6f6 182 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 109 161 6.3E-10 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_17645 6f74f57fb7fe6dee8e29d9f9ae01f6f6 182 Hamap MF_01515 UPF0316 protein . 1 169 28.572 T 01-11-2018 IPR022930 Protein of unknown function UPF0316 MLA2C4_04810 1fb988f3c5dbbefccf1c718d030a4787 471 PIRSF PIRSF500217 1 471 3.0E-154 T 01-11-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MLA2C4_04810 1fb988f3c5dbbefccf1c718d030a4787 471 PIRSF PIRSF016636 1 471 1.7E-151 T 01-11-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MLA2C4_04810 1fb988f3c5dbbefccf1c718d030a4787 471 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 146 342 1.3E-25 T 01-11-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MLA2C4_27815 2f1589883555f00278e698147ca232f2 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 233 5.9E-45 T 01-11-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MLA2C4_27815 2f1589883555f00278e698147ca232f2 241 Gene3D G3DSA:3.20.20.190 1 241 1.5E-84 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_27815 2f1589883555f00278e698147ca232f2 241 SUPERFAMILY SSF51695 2 240 2.93E-76 T 01-11-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MLA2C4_19040 5d482745b550e5a56ca802885b2e503d 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 1.9E-62 T 01-11-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MLA2C4_23180 d1d166eca227720471f7fd315e3ca80e 286 Pfam PF02163 Peptidase family M50 113 169 1.2E-7 T 01-11-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MLA2C4_14845 0640b8dffef1ef0449caa61d99fbb927 138 SUPERFAMILY SSF55729 29 138 8.97E-30 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14845 0640b8dffef1ef0449caa61d99fbb927 138 Gene3D G3DSA:3.40.630.30 35 138 6.1E-30 T 01-11-2018 MLA2C4_14845 0640b8dffef1ef0449caa61d99fbb927 138 Pfam PF00583 Acetyltransferase (GNAT) family 37 116 2.7E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_04965 d92b6ce2a4672cb669c4239b721dedbd 747 SUPERFAMILY SSF52540 406 624 1.35E-17 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_04965 d92b6ce2a4672cb669c4239b721dedbd 747 Pfam PF07728 AAA domain (dynein-related subfamily) 431 599 7.8E-9 T 01-11-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MLA2C4_02605 5a7510fcbb9a699b8f627a926dfbd93f 413 Pfam PF00144 Beta-lactamase 115 396 5.3E-56 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_02605 5a7510fcbb9a699b8f627a926dfbd93f 413 SUPERFAMILY SSF56601 103 408 7.52E-80 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_02605 5a7510fcbb9a699b8f627a926dfbd93f 413 Gene3D G3DSA:3.40.710.10 101 402 1.3E-82 T 01-11-2018 MLA2C4_10240 e87bfed07045b0dd95b2ba9ca260513c 122 Pfam PF13141 Protein of unknown function (DUF3979) 8 120 3.4E-69 T 01-11-2018 IPR025045 Protein of unknown function DUF3979 MLA2C4_03015 50504e4500a85e74023c8450e870b8dd 167 SUPERFAMILY SSF160387 50 159 4.71E-28 T 01-11-2018 MLA2C4_03015 50504e4500a85e74023c8450e870b8dd 167 Pfam PF05573 NosL 18 145 2.5E-19 T 01-11-2018 IPR008719 Nitrous oxide reductase accessory protein NosL MLA2C4_09500 22836e7c8117283c436c1dbc40c32c2c 307 SUPERFAMILY SSF53474 2 305 3.98E-38 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09500 22836e7c8117283c436c1dbc40c32c2c 307 Gene3D G3DSA:3.40.50.1820 2 306 3.2E-53 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09500 22836e7c8117283c436c1dbc40c32c2c 307 Pfam PF12146 Serine aminopeptidase, S33 26 289 2.5E-50 T 01-11-2018 IPR022742 Serine aminopeptidase, S33 MLA2C4_24330 cea1f78317c7c320a8abfbeab845eb51 371 Gene3D G3DSA:3.40.1830.10 2 165 3.4E-14 T 01-11-2018 IPR035097 Peptidase M29, N-terminal MLA2C4_24330 cea1f78317c7c320a8abfbeab845eb51 371 SUPERFAMILY SSF144052 1 360 5.89E-112 T 01-11-2018 MLA2C4_24330 cea1f78317c7c320a8abfbeab845eb51 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 338 4.7E-59 T 01-11-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 MLA2C4_20525 96670c59790cf505bfcd4ce37bdaec9a 408 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 10 378 1.3E-125 T 01-11-2018 IPR014226 Sporulation integral membrane protein YlbJ MLA2C4_19355 ed2b6f47bcdf54c82691679f29e30ed8 129 Pfam PF13411 MerR HTH family regulatory protein 13 76 3.7E-18 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_19355 ed2b6f47bcdf54c82691679f29e30ed8 129 SMART SM00422 11 79 6.8E-24 T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_19355 ed2b6f47bcdf54c82691679f29e30ed8 129 SUPERFAMILY SSF46955 11 98 2.98E-18 T 01-11-2018 IPR009061 Putative DNA-binding domain superfamily MLA2C4_19355 ed2b6f47bcdf54c82691679f29e30ed8 129 Gene3D G3DSA:1.10.1660.10 2 83 8.2E-24 T 01-11-2018 MLA2C4_19355 ed2b6f47bcdf54c82691679f29e30ed8 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 01-11-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MLA2C4_22800 707fc7e2ba82b1800aadc25492115d04 75 Pfam PF14143 YrhC-like protein 2 73 1.9E-25 T 01-11-2018 IPR025418 YrhC-like protein MLA2C4_17485 017a9d41bf5448b4b0bcb092261446c5 66 SMART SM00530 6 61 2.4E-17 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_17485 017a9d41bf5448b4b0bcb092261446c5 66 Gene3D G3DSA:1.10.260.40 3 66 5.2E-26 T 01-11-2018 MLA2C4_17485 017a9d41bf5448b4b0bcb092261446c5 66 Pfam PF01381 Helix-turn-helix 7 61 9.5E-18 T 01-11-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MLA2C4_17485 017a9d41bf5448b4b0bcb092261446c5 66 SUPERFAMILY SSF47413 1 65 9.92E-19 T 01-11-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MLA2C4_26955 4807dcad0c05b2aa6f803c123e079b51 403 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 183 196 - T 01-11-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_26955 4807dcad0c05b2aa6f803c123e079b51 403 Gene3D G3DSA:3.40.50.150 159 392 2.8E-54 T 01-11-2018 MLA2C4_26955 4807dcad0c05b2aa6f803c123e079b51 403 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 112 371 26.253 T 01-11-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 MLA2C4_26955 4807dcad0c05b2aa6f803c123e079b51 403 SUPERFAMILY SSF53335 126 344 7.79E-53 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_26955 4807dcad0c05b2aa6f803c123e079b51 403 Pfam PF01564 Spermine/spermidine synthase domain 162 339 1.6E-33 T 01-11-2018 MLA2C4_23430 bca7938ba25092bb0dda917b4f5cf55b 321 Pfam PF13536 Putative multidrug resistance efflux transporter 38 304 1.0E-90 T 01-11-2018 IPR032713 Putative multidrug resistance efflux transporter MLA2C4_03475 4949e1df81f8cd5d5266bdebd0d0e9d1 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 319 1.1E-39 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_03475 4949e1df81f8cd5d5266bdebd0d0e9d1 321 Gene3D G3DSA:1.10.3720.10 85 314 1.5E-17 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_03475 4949e1df81f8cd5d5266bdebd0d0e9d1 321 SUPERFAMILY SSF161098 91 302 5.76E-14 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 256 8.9E-58 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 SMART SM00079 35 257 7.1E-5 T 01-11-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 Gene3D G3DSA:3.40.190.10 123 215 1.2E-63 T 01-11-2018 MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 01-11-2018 IPR018313 Solute-binding protein family 3, conserved site MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 Gene3D G3DSA:3.40.190.10 37 256 1.2E-63 T 01-11-2018 MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 SMART SM00062 35 258 1.8E-67 T 01-11-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MLA2C4_21725 74c19c87a3a67d64f32d514e7abac1a9 259 SUPERFAMILY SSF53850 1 257 2.05E-65 T 01-11-2018 MLA2C4_23020 bd28890af4b75948a05b78ee43ba1248 127 Pfam PF12670 Protein of unknown function (DUF3792) 10 119 5.8E-19 T 01-11-2018 IPR023804 Protein of unknown function DUF3792, transmembrane MLA2C4_23020 bd28890af4b75948a05b78ee43ba1248 127 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 5.7E-26 T 01-11-2018 IPR023804 Protein of unknown function DUF3792, transmembrane MLA2C4_07770 326c5a48b4c0c513fe2822e2d43731b6 541 Pfam PF05140 ResB-like family 65 430 5.1E-72 T 01-11-2018 IPR007816 ResB-like domain MLA2C4_07770 326c5a48b4c0c513fe2822e2d43731b6 541 Pfam PF05140 ResB-like family 439 519 3.4E-16 T 01-11-2018 IPR007816 ResB-like domain MLA2C4_11265 6fbc51b61e1cd1d77c9a1f5ef9840ab6 119 Pfam PF13673 Acetyltransferase (GNAT) domain 11 112 1.0E-6 T 01-11-2018 IPR000182 GNAT domain MLA2C4_11265 6fbc51b61e1cd1d77c9a1f5ef9840ab6 119 SUPERFAMILY SSF55729 7 112 4.51E-12 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_11265 6fbc51b61e1cd1d77c9a1f5ef9840ab6 119 Gene3D G3DSA:3.40.630.30 2 118 8.2E-11 T 01-11-2018 MLA2C4_04820 fc75434eb1768813642ed5a5c6656b4d 343 Gene3D G3DSA:3.40.50.1110 125 314 4.8E-5 T 01-11-2018 IPR036514 SGNH hydrolase superfamily MLA2C4_04820 fc75434eb1768813642ed5a5c6656b4d 343 SUPERFAMILY SSF52266 54 311 3.92E-6 T 01-11-2018 MLA2C4_03575 41db11e3990b93f3969596a3f968392b 390 Gene3D G3DSA:3.20.20.10 19 262 4.4E-47 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_03575 41db11e3990b93f3969596a3f968392b 390 Pfam PF01168 Alanine racemase, N-terminal domain 17 191 4.0E-8 T 01-11-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MLA2C4_03575 41db11e3990b93f3969596a3f968392b 390 SUPERFAMILY SSF51419 17 273 3.11E-18 T 01-11-2018 IPR029066 PLP-binding barrel MLA2C4_22440 517eff1f9e54bb2334b64bb54a1cb9e2 270 Pfam PF03618 Kinase/pyrophosphorylase 6 260 1.1E-94 T 01-11-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 MLA2C4_22440 517eff1f9e54bb2334b64bb54a1cb9e2 270 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 60.39 T 01-11-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein MLA2C4_20555 6fd2a39cfc96b67d75b47ee3506d3dbc 190 SMART SM00855 3 147 2.0E-18 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_20555 6fd2a39cfc96b67d75b47ee3506d3dbc 190 SUPERFAMILY SSF53254 1 189 5.35E-46 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_20555 6fd2a39cfc96b67d75b47ee3506d3dbc 190 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 184 7.9E-44 T 01-11-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MLA2C4_20555 6fd2a39cfc96b67d75b47ee3506d3dbc 190 Gene3D G3DSA:3.40.50.1240 1 190 1.7E-45 T 01-11-2018 IPR029033 Histidine phosphatase superfamily MLA2C4_20555 6fd2a39cfc96b67d75b47ee3506d3dbc 190 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 01-11-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MLA2C4_02440 8486c9106562f6da47eee2eb53c742ee 74 Hamap MF_00829 UPF0435 protein . 6 73 20.593 T 01-11-2018 IPR009507 Protein of unknown function UPF0435 MLA2C4_02440 8486c9106562f6da47eee2eb53c742ee 74 Pfam PF06569 Protein of unknown function (DUF1128) 3 71 9.8E-32 T 01-11-2018 IPR009507 Protein of unknown function UPF0435 MLA2C4_13860 592b5842f17850c38fec64ca8ac9187d 223 Pfam PF17294 Uncharacterised lipoprotein family 30 198 9.0E-44 T 01-11-2018 IPR035253 Putative lipoprotein, bacteria MLA2C4_13860 592b5842f17850c38fec64ca8ac9187d 223 Gene3D G3DSA:2.40.40.60 63 166 2.6E-18 T 01-11-2018 MLA2C4_05575 3626a7f3c471dad38d43f9ca5a554fac 120 Pfam PF12732 YtxH-like protein 9 83 3.9E-10 T 01-11-2018 IPR024623 Uncharacterised protein family YtxH MLA2C4_15665 2092ed85791525c46e1b2bdb4229fc4d 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 300 9.9E-49 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_13915 56fdc0230ec713bfa751568ce2286ecb 198 Gene3D G3DSA:2.60.120.40 55 193 1.5E-10 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_13915 56fdc0230ec713bfa751568ce2286ecb 198 SUPERFAMILY SSF49842 58 190 3.48E-19 T 01-11-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 MLA2C4_10405 09ac9ef433fb45c456de522bf5d32f84 152 Pfam PF07875 Coat F domain 83 140 1.7E-8 T 01-11-2018 IPR012851 Spore coat protein CotF-like MLA2C4_25835 4074d16c2b67efe91fe8eb0c075f33c9 165 Gene3D G3DSA:3.10.290.10 103 165 4.6E-11 T 01-11-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MLA2C4_25835 4074d16c2b67efe91fe8eb0c075f33c9 165 SUPERFAMILY SSF55174 115 163 1.62E-7 T 01-11-2018 MLA2C4_14890 eb6a683b7595eba132547fbfe9e1d36b 127 SUPERFAMILY SSF110857 1 124 4.58E-33 T 01-11-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily MLA2C4_14890 eb6a683b7595eba132547fbfe9e1d36b 127 Gene3D G3DSA:3.10.490.10 1 124 1.8E-32 T 01-11-2018 MLA2C4_14890 eb6a683b7595eba132547fbfe9e1d36b 127 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 121 4.4E-24 T 01-11-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like MLA2C4_08580 93d823fb0ec6d63e53be3892ab1088e7 464 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 22 115 3.3E-12 T 01-11-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 MLA2C4_08580 93d823fb0ec6d63e53be3892ab1088e7 464 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 214 446 2.1E-26 T 01-11-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 MLA2C4_02720 6cdcabec6f02b8242307c2f2d1bce953 93 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 18 89 1.4E-27 T 01-11-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 MLA2C4_02720 6cdcabec6f02b8242307c2f2d1bce953 93 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 11 89 7.7E-30 T 01-11-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 MLA2C4_10340 6b4d75bf9e15f0b19e3dedbd86a85963 181 Gene3D G3DSA:3.40.50.720 1 107 9.8E-9 T 01-11-2018 MLA2C4_10340 6b4d75bf9e15f0b19e3dedbd86a85963 181 SUPERFAMILY SSF51735 3 85 2.41E-8 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_04360 093b813aa0e2f52dc9664fb79173a9f1 436 PIRSF PIRSF006351 1 434 5.4E-141 T 01-11-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 MLA2C4_04360 093b813aa0e2f52dc9664fb79173a9f1 436 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 426 5.6E-119 T 01-11-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 MLA2C4_04360 093b813aa0e2f52dc9664fb79173a9f1 436 Pfam PF02378 Phosphotransferase system, EIIC 29 352 2.8E-59 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_17005 c9fe9e940c8abbd7ab6d9706e0229190 374 SUPERFAMILY SSF58104 39 221 9.94E-5 T 01-11-2018 MLA2C4_17005 c9fe9e940c8abbd7ab6d9706e0229190 374 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 337 369 3.8E-4 T 01-11-2018 MLA2C4_14235 e961a8328be695befb1759455788602f 307 SUPERFAMILY SSF53590 2 306 1.18E-78 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_14235 e961a8328be695befb1759455788602f 307 Gene3D G3DSA:3.90.245.10 1 307 3.4E-75 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_14235 e961a8328be695befb1759455788602f 307 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 299 2.7E-63 T 01-11-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MLA2C4_18855 978811cff19000fc350f08893e39c308 193 Gene3D G3DSA:1.10.720.30 7 81 1.1E-5 T 01-11-2018 IPR036361 SAP domain superfamily MLA2C4_23820 52b21623313224981be5d0bcffa27d48 210 Pfam PF02659 Putative manganese efflux pump 127 208 7.1E-11 T 01-11-2018 IPR003810 Putative manganese efflux pump MLA2C4_23820 52b21623313224981be5d0bcffa27d48 210 Pfam PF02659 Putative manganese efflux pump 6 83 6.4E-10 T 01-11-2018 IPR003810 Putative manganese efflux pump MLA2C4_23820 52b21623313224981be5d0bcffa27d48 210 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 5 210 1.8E-74 T 01-11-2018 IPR014205 Sporulation protein YtaF MLA2C4_20560 93b048e0f2960ae23aee76119cbd5fe6 81 Pfam PF14003 YlbE-like protein 14 73 1.1E-26 T 01-11-2018 IPR025613 YlbE-like protein MLA2C4_01880 b85c48f806d220386551971118ec1daf 155 Pfam PF13787 Protein of unknown function with HXXEE motif 10 114 6.1E-13 T 01-11-2018 IPR025671 Protein of unknown function with HXXEE motif MLA2C4_25505 97795c33f5b413d743c753f0cd517056 77 Pfam PF04070 Domain of unknown function (DUF378) 3 61 4.7E-26 T 01-11-2018 IPR007211 Protein of unknown function DUF378 MLA2C4_15265 c269be988f63b02d2827b3dbf09ebddb 408 Gene3D G3DSA:1.20.1250.20 233 406 2.9E-18 T 01-11-2018 MLA2C4_15265 c269be988f63b02d2827b3dbf09ebddb 408 Gene3D G3DSA:1.20.1250.20 19 195 1.3E-24 T 01-11-2018 MLA2C4_15265 c269be988f63b02d2827b3dbf09ebddb 408 Pfam PF07690 Major Facilitator Superfamily 17 233 1.9E-27 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_15265 c269be988f63b02d2827b3dbf09ebddb 408 Pfam PF07690 Major Facilitator Superfamily 252 392 6.4E-16 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_15265 c269be988f63b02d2827b3dbf09ebddb 408 SUPERFAMILY SSF103473 9 393 2.09E-53 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_27290 1f90379bfccb0d276f1809335768fbc1 195 Pfam PF02397 Bacterial sugar transferase 1 189 7.7E-65 T 01-11-2018 IPR003362 Bacterial sugar transferase MLA2C4_10355 30e458b945a211670cb6e85afa853f2d 358 Pfam PF08757 CotH kinase protein 43 350 1.5E-85 T 01-11-2018 IPR014867 Spore coat protein CotH MLA2C4_24360 c756ba0244c19e3277019851889bda6f 301 SUPERFAMILY SSF103481 38 141 7.06E-17 T 01-11-2018 MLA2C4_24360 c756ba0244c19e3277019851889bda6f 301 Pfam PF00892 EamA-like transporter family 9 139 4.8E-25 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_24360 c756ba0244c19e3277019851889bda6f 301 Pfam PF00892 EamA-like transporter family 153 287 1.5E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_24360 c756ba0244c19e3277019851889bda6f 301 SUPERFAMILY SSF103481 189 286 3.27E-8 T 01-11-2018 MLA2C4_07940 1aa2eefd056470cac256da1e6cec6cd1 492 PIRSF PIRSF007466 1 492 4.5E-274 T 01-11-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 MLA2C4_07940 1aa2eefd056470cac256da1e6cec6cd1 492 SUPERFAMILY SSF52540 21 236 2.83E-14 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_07940 1aa2eefd056470cac256da1e6cec6cd1 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 2.4E-263 T 01-11-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 MLA2C4_07940 1aa2eefd056470cac256da1e6cec6cd1 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 5.7E-227 T 01-11-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 MLA2C4_07940 1aa2eefd056470cac256da1e6cec6cd1 492 Gene3D G3DSA:3.40.50.300 12 235 3.9E-10 T 01-11-2018 MLA2C4_03640 4106ca95d07a9246c645dead94d52d97 573 Pfam PF10101 Predicted membrane protein (DUF2339) 443 564 2.2E-9 T 01-11-2018 IPR019286 Protein of unknown function DUF2339, transmembrane MLA2C4_03640 4106ca95d07a9246c645dead94d52d97 573 Pfam PF10101 Predicted membrane protein (DUF2339) 96 401 6.6E-29 T 01-11-2018 IPR019286 Protein of unknown function DUF2339, transmembrane MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 Pfam PF02872 5'-nucleotidase, C-terminal domain 371 565 1.3E-21 T 01-11-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 747 777 2.3E-6 T 01-11-2018 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 ProSitePatterns PS00786 5'-nucleotidase signature 2. 131 142 - T 01-11-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 Pfam PF00746 LPXTG cell wall anchor motif 740 777 1.7E-6 T 01-11-2018 IPR019948 Gram-positive LPXTG cell wall anchor MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 Gene3D G3DSA:3.60.21.10 32 369 4.1E-117 T 01-11-2018 IPR029052 Metallo-dependent phosphatase-like MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 SUPERFAMILY SSF56300 36 379 5.61E-80 T 01-11-2018 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 Gene3D G3DSA:3.90.780.10 427 608 4.0E-54 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 PRINTS PR01607 Apyrase family signature 546 565 9.4E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 PRINTS PR01607 Apyrase family signature 38 56 9.4E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 PRINTS PR01607 Apyrase family signature 445 468 9.4E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 PRINTS PR01607 Apyrase family signature 243 260 9.4E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 PRINTS PR01607 Apyrase family signature 271 294 9.4E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 PRINTS PR01607 Apyrase family signature 297 317 9.4E-25 T 01-11-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 SUPERFAMILY SSF55816 371 609 2.88E-41 T 01-11-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MLA2C4_21575 a897e9cc6151e5afa1eea6a5b1ae59b8 780 Pfam PF00149 Calcineurin-like phosphoesterase 40 288 8.1E-14 T 01-11-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MLA2C4_25085 50dc455da9c71d832d91cf6a8425259b 169 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 18 153 4.0E-45 T 01-11-2018 IPR018697 Protein of unknown function DUF2199 MLA2C4_17735 4ebeafa1ad510d9e2a91fb8cf173fedd 158 PIRSF PIRSF008757 1 158 3.4E-59 T 01-11-2018 IPR010371 Uncharacterised protein family UPF0303 MLA2C4_17735 4ebeafa1ad510d9e2a91fb8cf173fedd 158 Gene3D G3DSA:3.30.450.150 2 158 1.4E-48 T 01-11-2018 IPR038084 GlcG-like domain superfamily MLA2C4_17735 4ebeafa1ad510d9e2a91fb8cf173fedd 158 Pfam PF03928 Haem-degrading 25 152 2.6E-30 T 01-11-2018 IPR005624 Haem-degrading MLA2C4_17735 4ebeafa1ad510d9e2a91fb8cf173fedd 158 Hamap MF_00761 UPF0303 protein . 3 158 32.718 T 01-11-2018 IPR010371 Uncharacterised protein family UPF0303 MLA2C4_17735 4ebeafa1ad510d9e2a91fb8cf173fedd 158 SUPERFAMILY SSF143744 17 156 2.22E-26 T 01-11-2018 IPR038084 GlcG-like domain superfamily MLA2C4_27830 2034b04c19092a944e033cd08a3bb0e5 224 Pfam PF02163 Peptidase family M50 128 179 1.5E-8 T 01-11-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MLA2C4_05165 55227d7ca6ec4b8a89d48b80c694f660 209 PIRSF PIRSF006324 1 207 2.8E-56 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_05165 55227d7ca6ec4b8a89d48b80c694f660 209 Pfam PF01810 LysE type translocator 16 203 9.7E-39 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_01375 6ce0ca154615910b670015fffdf97aeb 423 Pfam PF07690 Major Facilitator Superfamily 19 363 6.0E-45 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_01375 6ce0ca154615910b670015fffdf97aeb 423 Gene3D G3DSA:1.20.1250.20 205 413 4.6E-23 T 01-11-2018 MLA2C4_01375 6ce0ca154615910b670015fffdf97aeb 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_01375 6ce0ca154615910b670015fffdf97aeb 423 SUPERFAMILY SSF103473 9 414 4.19E-61 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_01375 6ce0ca154615910b670015fffdf97aeb 423 Gene3D G3DSA:1.20.1250.20 11 202 3.0E-34 T 01-11-2018 MLA2C4_16660 2dfb5ae94421966c76cd5c052fd6467d 120 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 112 1.0E-39 T 01-11-2018 IPR018745 Domain of unknown function DUF2294 MLA2C4_09480 a9e791b5f9c6e7954b82f01cc8f36a5c 238 Pfam PF04474 Protein of unknown function (DUF554) 4 226 1.2E-72 T 01-11-2018 IPR007563 Protein of unknown function DUF554 MLA2C4_22125 022ef1dd337cc501b41445fcf40ac6b8 264 ProDom PD123329 YQHG BH2818 1 257 3.0E-150 T 01-11-2018 IPR024562 Uncharacterised protein family YqhG MLA2C4_22125 022ef1dd337cc501b41445fcf40ac6b8 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 257 9.4E-127 T 01-11-2018 IPR024562 Uncharacterised protein family YqhG MLA2C4_00640 0b28e5f99649592bd9aff32701286c44 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 81 4.7E-12 T 01-11-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 MLA2C4_00640 0b28e5f99649592bd9aff32701286c44 82 SUPERFAMILY SSF55315 4 81 6.38E-17 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_00640 0b28e5f99649592bd9aff32701286c44 82 Gene3D G3DSA:3.30.1330.30 1 81 1.2E-18 T 01-11-2018 IPR029064 50S ribosomal protein L30e-like MLA2C4_15780 23bd1ffafe1fb16fbe6171eeed473466 343 Pfam PF00487 Fatty acid desaturase 52 290 3.5E-34 T 01-11-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MLA2C4_00175 33409e6b41327840677fae651c234c5c 59 Pfam PF10764 Inhibitor of sigma-G Gin 8 52 9.4E-19 T 01-11-2018 IPR019700 Anti-sigma-G factor Gin MLA2C4_13720 ae7686be5671c6f6ed066a293e92dbed 315 Pfam PF01636 Phosphotransferase enzyme family 28 224 1.6E-13 T 01-11-2018 IPR002575 Aminoglycoside phosphotransferase MLA2C4_13720 ae7686be5671c6f6ed066a293e92dbed 315 Gene3D G3DSA:3.90.1200.10 106 311 2.0E-20 T 01-11-2018 MLA2C4_13720 ae7686be5671c6f6ed066a293e92dbed 315 SUPERFAMILY SSF56112 5 314 2.29E-50 T 01-11-2018 IPR011009 Protein kinase-like domain superfamily MLA2C4_03725 44ce129b264f57606109e5dc6547f382 490 Pfam PF00474 Sodium:solute symporter family 34 427 1.0E-23 T 01-11-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MLA2C4_03725 44ce129b264f57606109e5dc6547f382 490 Gene3D G3DSA:1.20.1730.10 21 490 1.4E-35 T 01-11-2018 IPR038377 Sodium/glucose symporter superfamily MLA2C4_18300 d9373e32fc1e8b0d873bcd1a9ae7b959 225 PRINTS PR01837 MgtC/SapB protein signature 94 118 3.5E-48 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_18300 d9373e32fc1e8b0d873bcd1a9ae7b959 225 PRINTS PR01837 MgtC/SapB protein signature 14 33 3.5E-48 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_18300 d9373e32fc1e8b0d873bcd1a9ae7b959 225 PRINTS PR01837 MgtC/SapB protein signature 67 89 3.5E-48 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_18300 d9373e32fc1e8b0d873bcd1a9ae7b959 225 PRINTS PR01837 MgtC/SapB protein signature 33 51 3.5E-48 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_18300 d9373e32fc1e8b0d873bcd1a9ae7b959 225 Pfam PF02308 MgtC family 12 138 1.2E-37 T 01-11-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MLA2C4_16135 cff07fb11bcd5443b3296b76374834f0 210 SUPERFAMILY SSF53335 10 206 1.59E-34 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_16135 cff07fb11bcd5443b3296b76374834f0 210 Pfam PF04989 Cephalosporin hydroxylase 21 209 1.6E-70 T 01-11-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 MLA2C4_16135 cff07fb11bcd5443b3296b76374834f0 210 Gene3D G3DSA:3.40.50.150 34 199 3.1E-37 T 01-11-2018 MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 PIRSF PIRSF000379 8 749 0.0 T 01-11-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 749 0.0 T 01-11-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 Gene3D G3DSA:3.20.70.20 2 749 0.0 T 01-11-2018 MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 ProSitePatterns PS00850 Glycine radical domain signature. 719 727 - T 01-11-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 Pfam PF01228 Glycine radical 624 730 3.8E-44 T 01-11-2018 IPR001150 Glycine radical domain GO:0003824 MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 SUPERFAMILY SSF51998 8 749 2.61E-287 T 01-11-2018 MLA2C4_02645 52431fb8d3fe993b112ac560d011b4f7 749 Pfam PF02901 Pyruvate formate lyase-like 24 608 1.7E-209 T 01-11-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 MLA2C4_00330 5f73e30f11f3af5a594f67c753e86383 217 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 4.9E-23 T 01-11-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like MLA2C4_00330 5f73e30f11f3af5a594f67c753e86383 217 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 130 1.7E-48 T 01-11-2018 IPR014242 Spore cortex biosynthesis protein, YabQ MLA2C4_23555 8b212d3713ea9bf9a14c54c095ff6e46 167 SUPERFAMILY SSF109854 8 152 2.29E-32 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_23555 8b212d3713ea9bf9a14c54c095ff6e46 167 Pfam PF05163 DinB family 1 159 4.3E-33 T 01-11-2018 IPR007837 DNA damage-inducible protein DinB MLA2C4_23555 8b212d3713ea9bf9a14c54c095ff6e46 167 Gene3D G3DSA:1.20.120.450 1 150 6.8E-48 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_05245 ebcafcb0df66c955105b44b5ac9d69ad 352 Gene3D G3DSA:3.20.20.30 1 350 1.5E-148 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_05245 ebcafcb0df66c955105b44b5ac9d69ad 352 SUPERFAMILY SSF51679 3 342 3.4E-85 T 01-11-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MLA2C4_05245 ebcafcb0df66c955105b44b5ac9d69ad 352 Pfam PF00296 Luciferase-like monooxygenase 16 317 1.2E-74 T 01-11-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MLA2C4_11895 d1ee00a4b7b259ef43887580140eeda6 626 Gene3D G3DSA:2.60.120.560 445 617 5.1E-5 T 01-11-2018 MLA2C4_11895 d1ee00a4b7b259ef43887580140eeda6 626 Gene3D G3DSA:2.60.40.3350 3 119 1.1E-6 T 01-11-2018 MLA2C4_11895 d1ee00a4b7b259ef43887580140eeda6 626 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 265 330 2.0E-19 T 01-11-2018 MLA2C4_11895 d1ee00a4b7b259ef43887580140eeda6 626 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 351 416 7.7E-19 T 01-11-2018 MLA2C4_11895 d1ee00a4b7b259ef43887580140eeda6 626 Pfam PF10651 Domain of unknown function (DUF2479) 4 137 3.0E-16 T 01-11-2018 IPR018913 Domain of unknown function DUF2479 MLA2C4_05535 ffcca75e205899a85b507de4da484919 423 Pfam PF01098 Cell cycle protein 97 413 8.9E-39 T 01-11-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_14835 14b6746cb089c3ff4961f914bc743f83 70 Pfam PF11213 Protein of unknown function (DUF3006) 4 69 1.9E-26 T 01-11-2018 IPR021377 Protein of unknown function DUF3006 MLA2C4_26195 ad59298cae5df85211ca1e5bab95021e 147 Pfam PF13123 Protein of unknown function (DUF3978) 1 144 1.7E-96 T 01-11-2018 IPR025010 Protein of unknown function DUF3978 MLA2C4_25990 a97399496654ece216622bcd63e42ced 215 Gene3D G3DSA:1.20.144.10 119 215 2.3E-5 T 01-11-2018 MLA2C4_25990 a97399496654ece216622bcd63e42ced 215 Pfam PF14378 PAP2 superfamily 51 192 6.3E-11 T 01-11-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 MLA2C4_25990 a97399496654ece216622bcd63e42ced 215 SUPERFAMILY SSF48317 15 210 2.91E-7 T 01-11-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MLA2C4_04415 5d9ade5b0e68644cce3f7f67e67ae5fd 189 Gene3D G3DSA:1.20.1260.10 1 184 9.9E-65 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_04415 5d9ade5b0e68644cce3f7f67e67ae5fd 189 Pfam PF05067 Manganese containing catalase 1 185 2.9E-76 T 01-11-2018 IPR007760 Manganese catalase MLA2C4_04415 5d9ade5b0e68644cce3f7f67e67ae5fd 189 SUPERFAMILY SSF47240 1 186 8.75E-69 T 01-11-2018 IPR009078 Ferritin-like superfamily MLA2C4_09210 30bdd999d1a28f3000858c34d86b6aa0 302 Pfam PF13781 DoxX-like family 180 280 2.1E-25 T 01-11-2018 IPR025695 DoxX-like family MLA2C4_09210 30bdd999d1a28f3000858c34d86b6aa0 302 SUPERFAMILY SSF55961 1 159 1.43E-6 T 01-11-2018 MLA2C4_08090 ea69bb6a40ba7cf4314014ab022b8130 129 Gene3D G3DSA:2.60.40.420 30 129 2.2E-40 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_08090 ea69bb6a40ba7cf4314014ab022b8130 129 Pfam PF13473 Cupredoxin-like domain 29 128 1.3E-23 T 01-11-2018 IPR028096 EfeO-type cupredoxin-like domain MLA2C4_08090 ea69bb6a40ba7cf4314014ab022b8130 129 SUPERFAMILY SSF49503 35 128 1.15E-16 T 01-11-2018 IPR008972 Cupredoxin MLA2C4_02010 ee9b3f4f2bc8cf752fb8ec5f8639d8b3 473 Pfam PF03553 Na+/H+ antiporter family 158 450 9.0E-62 T 01-11-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MLA2C4_02010 ee9b3f4f2bc8cf752fb8ec5f8639d8b3 473 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 455 1.3E-144 T 01-11-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 MLA2C4_11770 b16a19e9b9e760dfdd220e8093e479e0 295 Pfam PF03592 Terminase small subunit 84 251 1.1E-39 T 01-11-2018 IPR005335 Terminase small subunit GO:0006323 MLA2C4_11770 b16a19e9b9e760dfdd220e8093e479e0 295 Gene3D G3DSA:1.10.10.1400 79 143 6.2E-15 T 01-11-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily MLA2C4_11770 b16a19e9b9e760dfdd220e8093e479e0 295 Pfam PF10668 Phage terminase small subunit 1 57 1.3E-22 T 01-11-2018 IPR018925 Phage terminase small subunit MLA2C4_09265 3d35f4f475b63224f21dde0662e155f6 416 SUPERFAMILY SSF53850 37 410 8.03E-84 T 01-11-2018 MLA2C4_09265 3d35f4f475b63224f21dde0662e155f6 416 Pfam PF01547 Bacterial extracellular solute-binding protein 49 329 2.3E-41 T 01-11-2018 IPR006059 Bacterial extracellular solute-binding protein MLA2C4_09265 3d35f4f475b63224f21dde0662e155f6 416 Gene3D G3DSA:3.40.190.10 25 414 2.2E-100 T 01-11-2018 MLA2C4_01360 db70bb334a5911a40ae41d2682e9d47e 318 SUPERFAMILY SSF56529 77 299 1.19E-69 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MLA2C4_01360 db70bb334a5911a40ae41d2682e9d47e 318 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 298 2.7E-63 T 01-11-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MLA2C4_01360 db70bb334a5911a40ae41d2682e9d47e 318 Gene3D G3DSA:3.90.850.10 26 303 6.6E-89 T 01-11-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MLA2C4_28110 a0659ec453d364cb8c90498f23313aa0 170 Pfam PF03061 Thioesterase superfamily 25 97 3.0E-14 T 01-11-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MLA2C4_28110 a0659ec453d364cb8c90498f23313aa0 170 Gene3D G3DSA:3.10.129.10 1 164 4.8E-53 T 01-11-2018 MLA2C4_28110 a0659ec453d364cb8c90498f23313aa0 170 SUPERFAMILY SSF54637 1 150 1.08E-42 T 01-11-2018 IPR029069 HotDog domain superfamily MLA2C4_08780 047d92a720c7e5f48e71e6ba07ff4e5e 197 SUPERFAMILY SSF53474 5 194 7.41E-22 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_08780 047d92a720c7e5f48e71e6ba07ff4e5e 197 Pfam PF01738 Dienelactone hydrolase family 3 194 7.8E-16 T 01-11-2018 IPR002925 Dienelactone hydrolase GO:0016787 MLA2C4_08780 047d92a720c7e5f48e71e6ba07ff4e5e 197 Gene3D G3DSA:3.40.50.1820 2 195 6.8E-23 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_22885 6defb555f7e93bf20b48bd86d1f74077 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 7.4E-38 T 01-11-2018 IPR009309 Uncharacterised protein family UPF0297 MLA2C4_22885 6defb555f7e93bf20b48bd86d1f74077 88 Hamap MF_01507 UPF0297 protein . 1 85 28.197 T 01-11-2018 IPR009309 Uncharacterised protein family UPF0297 MLA2C4_22885 6defb555f7e93bf20b48bd86d1f74077 88 PIRSF PIRSF037258 1 88 1.7E-45 T 01-11-2018 IPR009309 Uncharacterised protein family UPF0297 MLA2C4_18830 970fae47f6cf441031df388dffeb9cf4 128 Gene3D G3DSA:2.60.40.790 32 114 1.3E-9 T 01-11-2018 IPR008978 HSP20-like chaperone MLA2C4_18830 970fae47f6cf441031df388dffeb9cf4 128 SUPERFAMILY SSF49764 30 119 2.44E-13 T 01-11-2018 IPR008978 HSP20-like chaperone MLA2C4_28075 545c54bf52416218bec9aa836dbc4bb8 399 Gene3D G3DSA:1.20.1250.20 9 399 3.0E-93 T 01-11-2018 MLA2C4_28075 545c54bf52416218bec9aa836dbc4bb8 399 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_28075 545c54bf52416218bec9aa836dbc4bb8 399 Pfam PF07690 Major Facilitator Superfamily 21 263 1.5E-39 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_28075 545c54bf52416218bec9aa836dbc4bb8 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 269 284 - T 01-11-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MLA2C4_28075 545c54bf52416218bec9aa836dbc4bb8 399 SUPERFAMILY SSF103473 9 397 9.94E-89 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_02970 2f224257e2dfdebd3483c62c92c49ec5 516 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 499 3.4E-149 T 01-11-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MLA2C4_02970 2f224257e2dfdebd3483c62c92c49ec5 516 ProSitePatterns PS01303 BCCT family of transporters signature. 316 325 - T 01-11-2018 IPR018093 BCCT transporter, conserved site MLA2C4_02970 2f224257e2dfdebd3483c62c92c49ec5 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 499 4.1E-186 T 01-11-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MLA2C4_07585 6a3f114d1a4fa1160209b1b0b8d5b935 220 Pfam PF04012 PspA/IM30 family 5 208 7.3E-28 T 01-11-2018 IPR007157 PspA/IM30 MLA2C4_14040 56c315627cfab9a6dc1844fe5c893b0b 51 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 1.6E-15 T 01-11-2018 IPR011437 Domain of unknown function DUF1540 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 Gene3D G3DSA:1.20.1720.10 12 246 4.0E-41 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 SUPERFAMILY SSF103473 9 431 5.23E-59 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 Pfam PF07690 Major Facilitator Superfamily 16 398 1.1E-45 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 1.4E-23 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 291 315 1.4E-23 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 222 240 1.4E-23 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 1.4E-23 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 1.4E-23 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 161 185 1.4E-23 T 01-11-2018 MLA2C4_23385 e0ab558fe7b8a161451cb7c437faf27f 441 Gene3D G3DSA:1.20.1250.20 248 440 7.3E-20 T 01-11-2018 MLA2C4_25235 2530b1176719d76c55ee23329cfe97ef 286 SUPERFAMILY SSF55166 93 222 4.19E-27 T 01-11-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MLA2C4_25235 2530b1176719d76c55ee23329cfe97ef 286 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 99 213 1.2E-28 T 01-11-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MLA2C4_25235 2530b1176719d76c55ee23329cfe97ef 286 Gene3D G3DSA:3.30.1380.10 68 211 2.3E-79 T 01-11-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MLA2C4_25235 2530b1176719d76c55ee23329cfe97ef 286 Gene3D G3DSA:3.30.200.180 48 284 2.3E-79 T 01-11-2018 MLA2C4_12730 5184d8933a5a642d5b58ba45109c2558 370 PIRSF PIRSF026508 13 370 8.5E-96 T 01-11-2018 IPR008863 Toxic anion resistance MLA2C4_12730 5184d8933a5a642d5b58ba45109c2558 370 Pfam PF05816 Toxic anion resistance protein (TelA) 58 365 8.6E-54 T 01-11-2018 IPR008863 Toxic anion resistance MLA2C4_14150 efd80ca20b824b1895a04ef61aa99b49 340 Pfam PF00144 Beta-lactamase 25 328 5.9E-41 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_14150 efd80ca20b824b1895a04ef61aa99b49 340 SUPERFAMILY SSF56601 4 328 1.71E-73 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_14150 efd80ca20b824b1895a04ef61aa99b49 340 Gene3D G3DSA:3.40.710.10 6 340 5.7E-107 T 01-11-2018 MLA2C4_27025 c055bb244f8760fa099a8dfe8617b78b 452 PRINTS PR00758 Arsenical pump membrane protein signature 385 410 3.1E-24 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_27025 c055bb244f8760fa099a8dfe8617b78b 452 PRINTS PR00758 Arsenical pump membrane protein signature 344 366 3.1E-24 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_27025 c055bb244f8760fa099a8dfe8617b78b 452 PRINTS PR00758 Arsenical pump membrane protein signature 418 442 3.1E-24 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_27025 c055bb244f8760fa099a8dfe8617b78b 452 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 3.1E-24 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_27025 c055bb244f8760fa099a8dfe8617b78b 452 Pfam PF02040 Arsenical pump membrane protein 8 446 3.3E-69 T 01-11-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MLA2C4_26450 4f037d73e54b34a42f02d67ce368c14a 185 Gene3D G3DSA:3.40.50.850 1 185 2.8E-48 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_26450 4f037d73e54b34a42f02d67ce368c14a 185 SUPERFAMILY SSF52499 2 182 3.14E-49 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_26450 4f037d73e54b34a42f02d67ce368c14a 185 Pfam PF00857 Isochorismatase family 4 148 7.3E-39 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_15085 59a6c2bcaa849a98c2649a31e1fce1c3 108 Pfam PF12986 Domain of unknown function (DUF3870) 8 99 5.3E-33 T 01-11-2018 IPR024617 Domain of unknown function DUF3870 MLA2C4_17900 e789c218ae7375d1ffa7d1a8c19f0c47 113 PIRSF PIRSF029876 3 111 2.0E-45 T 01-11-2018 IPR008316 Uncharacterised conserved protein UCP029876 MLA2C4_17900 e789c218ae7375d1ffa7d1a8c19f0c47 113 Gene3D G3DSA:1.10.1900.10 1 109 4.1E-39 T 01-11-2018 MLA2C4_17900 e789c218ae7375d1ffa7d1a8c19f0c47 113 SUPERFAMILY SSF158560 1 108 1.83E-34 T 01-11-2018 MLA2C4_17900 e789c218ae7375d1ffa7d1a8c19f0c47 113 Pfam PF06304 Protein of unknown function (DUF1048) 7 106 9.8E-42 T 01-11-2018 IPR008316 Uncharacterised conserved protein UCP029876 MLA2C4_10140 6396ddaab22527d28d660ea31fe00473 48 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 20 42 2.7E-10 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_10140 6396ddaab22527d28d660ea31fe00473 48 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 18 40 2.0E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_20275 9d7b6dad994b5f623f7270c396a870e9 122 Pfam PF14037 YoqO-like protein 4 118 6.7E-48 T 01-11-2018 IPR025621 YoqO-like protein MLA2C4_15200 5d3a24b39fedcae95ecb4b1f2589a301 224 Pfam PF07552 Spore Coat Protein X and V domain 166 223 1.9E-23 T 01-11-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 MLA2C4_15200 5d3a24b39fedcae95ecb4b1f2589a301 224 Pfam PF07552 Spore Coat Protein X and V domain 104 159 1.2E-19 T 01-11-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 MLA2C4_06425 ebd4a623e96d8d7382b71d529e5b67d1 156 Pfam PF10612 Spore coat protein Z 4 153 2.4E-41 T 01-11-2018 IPR019593 Spore coat protein Z/Y MLA2C4_27975 54ae58374970af0baf6f2d7211d8495c 330 Pfam PF12679 ABC-2 family transporter protein 6 328 7.4E-25 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_22495 dd3e6951a8340cb3bf32f8401f4bcefa 97 Pfam PF07873 YabP family 26 89 2.2E-16 T 01-11-2018 IPR022476 Sporulation protein YabP/YqfC MLA2C4_22495 dd3e6951a8340cb3bf32f8401f4bcefa 97 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 7 90 2.6E-36 T 01-11-2018 IPR022477 Sporulation protein YqfC MLA2C4_04620 dd3ecf2a395c1b6175484b394490ddca 399 PIRSF PIRSF037259 1 397 1.3E-118 T 01-11-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 MLA2C4_04620 dd3ecf2a395c1b6175484b394490ddca 399 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 380 2.9E-105 T 01-11-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 SUPERFAMILY SSF51735 2 248 4.78E-45 T 01-11-2018 IPR036291 NAD(P)-binding domain superfamily MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 01-11-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 Pfam PF00106 short chain dehydrogenase 3 201 2.1E-39 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-16 T 01-11-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MLA2C4_18415 e61d3b13dc12f39a1dd92b8701c53c65 249 Gene3D G3DSA:3.40.50.720 1 248 1.9E-52 T 01-11-2018 MLA2C4_27165 fedc92c5eaf00aa74547bce3f3a61882 233 Pfam PF06930 Protein of unknown function (DUF1282) 20 214 1.7E-44 T 01-11-2018 IPR009698 Protein of unknown function DUF1282 MLA2C4_22560 12e1992f05b2176c51a203fdce50a189 120 Pfam PF12438 Protein of unknown function (DUF3679) 15 68 1.9E-22 T 01-11-2018 IPR020534 Uncharacterised protein family YqxA MLA2C4_22560 12e1992f05b2176c51a203fdce50a189 120 ProDom PD072942 YQXA ORF79 8 97 7.0E-30 T 01-11-2018 IPR020534 Uncharacterised protein family YqxA MLA2C4_06035 44cb726566469594e4187399a5a877d2 59 Pfam PF09388 Spo0E like sporulation regulatory protein 3 39 3.1E-15 T 01-11-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 MLA2C4_06035 44cb726566469594e4187399a5a877d2 59 Gene3D G3DSA:1.20.58.990 1 59 5.2E-21 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_06035 44cb726566469594e4187399a5a877d2 59 SUPERFAMILY SSF140500 3 51 2.88E-16 T 01-11-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 MLA2C4_18825 89d9b092ce78e9c8914a662394fbbf75 40 Pfam PF08179 Small acid-soluble spore protein P family 4 35 5.2E-15 T 01-11-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 MLA2C4_05435 db4f87025a9094216af23a560f95fda8 127 Pfam PF12676 Protein of unknown function (DUF3796) 3 110 4.3E-11 T 01-11-2018 IPR024257 Protein of unknown function DUF3796 MLA2C4_12305 2035b0815ac82c0e3d40616fa540d383 334 SUPERFAMILY SSF161098 74 281 1.24E-12 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_12305 2035b0815ac82c0e3d40616fa540d383 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 298 7.2E-10 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_12305 2035b0815ac82c0e3d40616fa540d383 334 Gene3D G3DSA:1.10.3720.10 68 299 1.0E-16 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_12335 9a3dcb8cf84242d89ff5d1948eeb5a33 288 Pfam PF00753 Metallo-beta-lactamase superfamily 28 223 1.8E-18 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_12335 9a3dcb8cf84242d89ff5d1948eeb5a33 288 Gene3D G3DSA:3.60.15.10 2 243 4.0E-37 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_12335 9a3dcb8cf84242d89ff5d1948eeb5a33 288 SMART SM00849 23 223 8.0E-19 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_12335 9a3dcb8cf84242d89ff5d1948eeb5a33 288 SUPERFAMILY SSF56281 24 237 1.7E-37 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_27695 4d8cc936f86188589d496a91a08c0951 48 Pfam PF05968 Bacillus PapR protein 1 48 7.7E-35 T 01-11-2018 IPR009239 Bacillus PapR MLA2C4_08560 d840cceeadd39fbd3055e4f4346606a2 154 SUPERFAMILY SSF158397 36 153 1.06E-25 T 01-11-2018 IPR024042 TM1646-like domain superfamily MLA2C4_08560 d840cceeadd39fbd3055e4f4346606a2 154 Gene3D G3DSA:1.20.120.490 29 153 5.2E-25 T 01-11-2018 IPR024042 TM1646-like domain superfamily MLA2C4_08560 d840cceeadd39fbd3055e4f4346606a2 154 Pfam PF03885 Protein of unknown function (DUF327) 26 153 1.4E-24 T 01-11-2018 IPR005585 Protein of unknown function DUF327 MLA2C4_26700 90ca7ca7e734a1a2c2e957bd3d9e99f1 270 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 256 1.9E-78 T 01-11-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MLA2C4_26700 90ca7ca7e734a1a2c2e957bd3d9e99f1 270 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 261 17.741 T 01-11-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MLA2C4_26700 90ca7ca7e734a1a2c2e957bd3d9e99f1 270 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 260 2.0E-85 T 01-11-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MLA2C4_26700 90ca7ca7e734a1a2c2e957bd3d9e99f1 270 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 137 149 - T 01-11-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MLA2C4_06160 e7f2014022b975b0e944cdcd3cf2299e 60 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 9.9E-21 T 01-11-2018 IPR021324 Protein of unknown function DUF2929 MLA2C4_07235 cf3718ab2c393177956bb25edff0ccb9 132 Pfam PF07179 SseB protein N-terminal domain 10 120 1.9E-14 T 01-11-2018 IPR009839 SseB protein N-terminal domain MLA2C4_17965 af43f000db05c14449d66eeac191d33f 230 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 1.1E-6 T 01-11-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MLA2C4_17965 af43f000db05c14449d66eeac191d33f 230 Pfam PF00027 Cyclic nucleotide-binding domain 35 117 1.3E-12 T 01-11-2018 IPR000595 Cyclic nucleotide-binding domain MLA2C4_17965 af43f000db05c14449d66eeac191d33f 230 Gene3D G3DSA:1.10.10.10 151 227 3.4E-8 T 01-11-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MLA2C4_17965 af43f000db05c14449d66eeac191d33f 230 SUPERFAMILY SSF46785 151 226 4.54E-10 T 01-11-2018 IPR036390 Winged helix DNA-binding domain superfamily MLA2C4_17965 af43f000db05c14449d66eeac191d33f 230 Gene3D G3DSA:2.60.120.10 10 146 1.1E-18 T 01-11-2018 IPR014710 RmlC-like jelly roll fold MLA2C4_17965 af43f000db05c14449d66eeac191d33f 230 SUPERFAMILY SSF51206 21 140 1.24E-25 T 01-11-2018 IPR018490 Cyclic nucleotide-binding-like MLA2C4_12670 51e24f359bc80e6dba8e2b374f6bdf8a 397 Pfam PF07859 alpha/beta hydrolase fold 164 372 1.6E-23 T 01-11-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 MLA2C4_12670 51e24f359bc80e6dba8e2b374f6bdf8a 397 Gene3D G3DSA:3.40.50.1820 137 395 1.2E-56 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_12670 51e24f359bc80e6dba8e2b374f6bdf8a 397 SUPERFAMILY SSF53474 138 394 1.62E-46 T 01-11-2018 IPR029058 Alpha/Beta hydrolase fold MLA2C4_09910 5d011e0c41ed15fc2f0fa98567d8cc23 199 SUPERFAMILY SSF55469 4 198 1.23E-71 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_09910 5d011e0c41ed15fc2f0fa98567d8cc23 199 Gene3D G3DSA:3.40.109.10 2 199 1.2E-90 T 01-11-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MLA2C4_09910 5d011e0c41ed15fc2f0fa98567d8cc23 199 Pfam PF00881 Nitroreductase family 9 178 2.0E-20 T 01-11-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MLA2C4_28140 e589c386623655edf9ecfd6746e59069 127 Pfam PF04138 GtrA-like protein 6 119 8.0E-31 T 01-11-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 MLA2C4_27790 0d1796dfc55fcdc0064ad7c76cf8f25d 345 Pfam PF13303 Phosphotransferase system, EIIC 28 331 3.9E-59 T 01-11-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MLA2C4_06150 474fc3289b6590e73c5d7297f39dd425 59 Pfam PF14168 YjzC-like protein 1 55 7.1E-28 T 01-11-2018 IPR025549 YjzC-like protein MLA2C4_07325 e94e60f8259226aac11e55d15ce70674 195 Pfam PF14595 Thioredoxin 21 149 6.8E-41 T 01-11-2018 MLA2C4_07325 e94e60f8259226aac11e55d15ce70674 195 Gene3D G3DSA:3.40.30.10 11 180 1.2E-17 T 01-11-2018 MLA2C4_07325 e94e60f8259226aac11e55d15ce70674 195 SUPERFAMILY SSF52833 58 145 1.54E-8 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_16060 a7f9a9eb3ffb949551c6d2b73ac81789 274 Pfam PF10978 Protein of unknown function (DUF2785) 81 249 3.3E-51 T 01-11-2018 IPR021247 Protein of unknown function DUF2785 MLA2C4_02130 ed7d63f3ed90799c035d727715589542 369 SUPERFAMILY SSF52540 28 172 6.16E-9 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02130 ed7d63f3ed90799c035d727715589542 369 Gene3D G3DSA:3.40.50.300 7 180 4.7E-6 T 01-11-2018 MLA2C4_02130 ed7d63f3ed90799c035d727715589542 369 SUPERFAMILY SSF52540 210 292 3.46E-7 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_02405 fd3e5eae95c9e2159e773864789277d5 198 Gene3D G3DSA:2.60.60.30 19 194 7.3E-57 T 01-11-2018 MLA2C4_02405 fd3e5eae95c9e2159e773864789277d5 198 Pfam PF02342 TerD domain 1 197 4.0E-67 T 01-11-2018 IPR003325 TerD domain MLA2C4_13405 942ab44bc6d5fc9aaaae4516f77a32d1 359 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 194 356 5.6E-31 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_13405 942ab44bc6d5fc9aaaae4516f77a32d1 359 Gene3D G3DSA:3.30.300.210 212 359 4.4E-19 T 01-11-2018 IPR038501 Spore germination GerAC superfamily MLA2C4_13405 942ab44bc6d5fc9aaaae4516f77a32d1 359 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 3 358 1.1E-100 T 01-11-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 MLA2C4_08410 1909dbfa7d80a00f2a0b2c8d67ef6389 92 Pfam PF13143 Protein of unknown function (DUF3986) 3 89 6.3E-27 T 01-11-2018 IPR025047 Protein of unknown function DUF3986 MLA2C4_06610 f500251b149de251be0cdd5ac3d3b72c 60 Pfam PF13121 Domain of unknown function (DUF3976) 17 56 9.7E-30 T 01-11-2018 IPR025008 Domain of unknown function DUF3976 MLA2C4_08435 4a5f80ecc8fee5bd536fad4e89fc0fa7 221 Gene3D G3DSA:3.30.240.20 77 146 6.8E-20 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_08435 4a5f80ecc8fee5bd536fad4e89fc0fa7 221 Gene3D G3DSA:3.30.240.20 162 221 2.7E-17 T 01-11-2018 IPR023090 UPF0702, alpha/beta domain superfamily MLA2C4_08435 4a5f80ecc8fee5bd536fad4e89fc0fa7 221 Pfam PF04239 Protein of unknown function (DUF421) 82 198 1.1E-32 T 01-11-2018 IPR007353 Protein of unknown function DUF421 MLA2C4_23980 771ef4fde77ea96f5e75117203feb9d8 275 Pfam PF10978 Protein of unknown function (DUF2785) 76 249 3.8E-50 T 01-11-2018 IPR021247 Protein of unknown function DUF2785 MLA2C4_08825 d670615caf537745cf1892e4539478be 422 Gene3D G3DSA:1.20.1250.20 13 410 1.0E-41 T 01-11-2018 MLA2C4_08825 d670615caf537745cf1892e4539478be 422 SUPERFAMILY SSF103473 18 409 2.49E-44 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_08825 d670615caf537745cf1892e4539478be 422 Pfam PF07690 Major Facilitator Superfamily 24 377 1.2E-26 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_07210 809099e59ae8037f49ea0e2d38b67d95 337 Pfam PF02517 CAAX protease self-immunity 130 213 2.6E-20 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_07210 809099e59ae8037f49ea0e2d38b67d95 337 SUPERFAMILY SSF89447 294 336 8.55E-5 T 01-11-2018 IPR037914 SpoVT-AbrB domain superfamily MLA2C4_15510 4d54b669a12f8d5f088861c4edbf180d 233 Pfam PF01909 Nucleotidyltransferase domain 23 43 3.5E-5 T 01-11-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MLA2C4_15510 4d54b669a12f8d5f088861c4edbf180d 233 Gene3D G3DSA:3.30.460.10 5 113 1.1E-10 T 01-11-2018 MLA2C4_15510 4d54b669a12f8d5f088861c4edbf180d 233 SUPERFAMILY SSF81301 6 109 1.2E-11 T 01-11-2018 MLA2C4_07005 4137182e0f1b7f3247d7c9303a6d28dd 449 Pfam PF02386 Cation transport protein 40 429 5.3E-60 T 01-11-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MLA2C4_05235 d25f680f215585a29c5316977bf7b647 45 TIGRFAM TIGR04429 Phr_nterm: Phr family secreted Rap phosphatase inhibitor 1 27 1.6E-7 T 01-11-2018 IPR030968 Phr family, secreted RapG/RapK phosphatase inhibitor MLA2C4_06225 d793065c6f07d36cd261d76a00ea9442 338 Gene3D G3DSA:1.10.3720.10 125 337 4.0E-26 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06225 d793065c6f07d36cd261d76a00ea9442 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 154 338 1.0E-31 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_06225 d793065c6f07d36cd261d76a00ea9442 338 SUPERFAMILY SSF161098 129 318 3.14E-31 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_06225 d793065c6f07d36cd261d76a00ea9442 338 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 84 2.8E-14 T 01-11-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MLA2C4_11515 3c192378a830a6036c119d2ca9821e25 55 Pfam PF13067 Protein of unknown function (DUF3930) 1 55 2.8E-42 T 01-11-2018 IPR025172 Protein of unknown function DUF3930 MLA2C4_04420 32504d85d562ed357af3874acadf669a 87 PIRSF PIRSF010606 1 87 3.6E-43 T 01-11-2018 IPR016571 Spore coat assembly protein CotJB MLA2C4_04420 32504d85d562ed357af3874acadf669a 87 Pfam PF12652 CotJB protein 11 86 5.5E-29 T 01-11-2018 IPR024207 Spore coat assembly protein CotJB, domain MLA2C4_16320 c845478f3f49b03d5b8886706a9b69d2 158 Pfam PF10710 Protein of unknown function (DUF2512) 1 140 2.1E-46 T 01-11-2018 IPR019649 Protein of unknown function DUF2512 MLA2C4_08310 264664446da272437b5fbddc6bd8c6c9 46 Pfam PF13040 Fur-regulated basic protein B 2 39 1.1E-14 T 01-11-2018 IPR025004 Transcriptional regulatory protein SenN/SenS MLA2C4_20660 bbc4869f30d510744c58816427d4bf0f 100 Pfam PF14036 YlaH-like protein 16 91 1.3E-32 T 01-11-2018 IPR025620 YlaH-like protein MLA2C4_15335 efe498e18774d36da2550951c6ef3f5d 65 Pfam PF04657 Putative inner membrane exporter, YdcZ 3 52 1.3E-4 T 01-11-2018 IPR006750 Putative inner membrane exporter, YdcZ MLA2C4_11985 6719d3441d59e1369c3895cecfbef635 45 Pfam PF13104 Protein of unknown function (DUF3956) 1 45 7.5E-32 T 01-11-2018 IPR025225 Protein of unknown function DUF3956 MLA2C4_15495 51100e3c184793bcb4fcbce2341fd761 173 Pfam PF04978 Protein of unknown function (DUF664) 17 166 1.6E-15 T 01-11-2018 IPR007061 Protein of unknown function DUF664 MLA2C4_15495 51100e3c184793bcb4fcbce2341fd761 173 Gene3D G3DSA:1.20.120.450 1 168 5.0E-27 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_15495 51100e3c184793bcb4fcbce2341fd761 173 SUPERFAMILY SSF109854 7 166 2.59E-32 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_03420 fc2e983ec4bc546200583f8f91e883a4 478 Pfam PF14285 Domain of unknown function (DUF4367) 116 223 1.4E-10 T 01-11-2018 IPR025377 Domain of unknown function DUF4367 MLA2C4_09625 89b83e2cacb77225e3e86d5049e6217e 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.2E-23 T 01-11-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MLA2C4_09625 89b83e2cacb77225e3e86d5049e6217e 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 1.1E-62 T 01-11-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MLA2C4_09625 89b83e2cacb77225e3e86d5049e6217e 393 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 392 2.3E-139 T 01-11-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 MLA2C4_17155 47a0e8962410a62ded496697798088c8 192 Pfam PF13796 Putative sensor 11 186 1.2E-23 T 01-11-2018 IPR025828 Putative sensor domain MLA2C4_12995 bde73cdb50d65a7d5c4632c9d767bf4a 505 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 32 484 4.7E-21 T 01-11-2018 IPR021145 Portal protein MLA2C4_26155 3a41246fb60f4dc581bddf71a210b079 173 Pfam PF13302 Acetyltransferase (GNAT) domain 7 145 3.4E-22 T 01-11-2018 IPR000182 GNAT domain MLA2C4_26155 3a41246fb60f4dc581bddf71a210b079 173 Gene3D G3DSA:3.40.630.30 2 172 1.8E-38 T 01-11-2018 MLA2C4_26155 3a41246fb60f4dc581bddf71a210b079 173 SUPERFAMILY SSF55729 3 169 4.21E-36 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_05050 bb4f624574309b42993fbc973bcaa985 41 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 10 33 7.6E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_05050 bb4f624574309b42993fbc973bcaa985 41 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 4.4E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_28255 824a369c1497b9395e2bc096735d8694 484 Pfam PF16933 Putative exopolysaccharide Exporter (EPS-E) 1 461 1.7E-135 T 01-11-2018 IPR031617 Putative exopolysaccharide exporter MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 PRINTS PR00181 Maltose binding protein signature 78 96 2.7E-8 T 01-11-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 PRINTS PR00181 Maltose binding protein signature 245 264 2.7E-8 T 01-11-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 PRINTS PR00181 Maltose binding protein signature 138 157 2.7E-8 T 01-11-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 PRINTS PR00181 Maltose binding protein signature 159 178 2.7E-8 T 01-11-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 PRINTS PR00181 Maltose binding protein signature 370 389 2.7E-8 T 01-11-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 Gene3D G3DSA:3.40.190.10 147 403 1.6E-115 T 01-11-2018 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 Pfam PF13416 Bacterial extracellular solute-binding protein 56 357 1.2E-57 T 01-11-2018 IPR006059 Bacterial extracellular solute-binding protein MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 Gene3D G3DSA:3.40.190.10 59 370 1.6E-115 T 01-11-2018 MLA2C4_20980 e257ad9c03c61c8d5aa99ea958b235d0 419 SUPERFAMILY SSF53850 42 407 5.69E-95 T 01-11-2018 MLA2C4_18310 f424d78f0c9192ad1c9198b742874ed7 305 Gene3D G3DSA:3.40.630.30 5 141 5.5E-7 T 01-11-2018 MLA2C4_18310 f424d78f0c9192ad1c9198b742874ed7 305 SUPERFAMILY SSF55729 44 243 2.92E-7 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_14645 4df7064372f2e03ef001e0ef023e9e30 81 Pfam PF13122 Protein of unknown function (DUF3977) 1 77 3.4E-48 T 01-11-2018 IPR025009 Protein of unknown function DUF3977 MLA2C4_14730 f955206d379d16a8ff1efb97ac1d5920 107 Pfam PF13789 Domain of unknown function (DUF4181) 2 97 4.5E-19 T 01-11-2018 IPR025441 Protein of unknown function DUF4181 MLA2C4_00195 7832bdf1cf97366e805c16a059a7ac75 275 Pfam PF04468 PSP1 C-terminal conserved region 61 146 9.3E-33 T 01-11-2018 IPR007557 PSP1, C-terminal MLA2C4_05035 679c2294569ca46872f59a5d616dc0ee 175 Pfam PF03773 Predicted permease 31 171 3.6E-16 T 01-11-2018 IPR005524 Predicted permease DUF318 MLA2C4_25620 f098a4d9224d96c21ff0803527015758 208 Pfam PF06725 3D domain 115 176 6.2E-19 T 01-11-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MLA2C4_25620 f098a4d9224d96c21ff0803527015758 208 SUPERFAMILY SSF50685 115 157 3.84E-7 T 01-11-2018 IPR036908 RlpA-like domain superfamily MLA2C4_06405 42766e3c32c472f26ffbaca777ce08db 152 Pfam PF10612 Spore coat protein Z 1 149 2.0E-45 T 01-11-2018 IPR019593 Spore coat protein Z/Y MLA2C4_16170 9537c61a54572b8d2d93035eb274881f 231 Pfam PF06149 Protein of unknown function (DUF969) 1 216 2.4E-86 T 01-11-2018 IPR010374 Protein of unknown function DUF969 MLA2C4_16370 30ab1f3cef943dccdb8ae479a06f4d98 466 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 46 223 3.0E-58 T 01-11-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 MLA2C4_16370 30ab1f3cef943dccdb8ae479a06f4d98 466 SUPERFAMILY SSF58100 32 367 8.89E-95 T 01-11-2018 MLA2C4_16370 30ab1f3cef943dccdb8ae479a06f4d98 466 Gene3D G3DSA:1.20.1170.10 39 372 2.7E-108 T 01-11-2018 MLA2C4_12495 ac70758ea6cb2c4b24cae6f42078fecf 374 SUPERFAMILY SSF56235 101 234 5.86E-6 T 01-11-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MLA2C4_12495 ac70758ea6cb2c4b24cae6f42078fecf 374 Gene3D G3DSA:3.60.60.10 92 368 2.4E-37 T 01-11-2018 MLA2C4_12495 ac70758ea6cb2c4b24cae6f42078fecf 374 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 105 331 1.2E-59 T 01-11-2018 IPR005079 Peptidase C45 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 Gene3D G3DSA:2.40.10.10 119 220 5.8E-61 T 01-11-2018 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 Pfam PF00089 Trypsin 128 309 3.8E-13 T 01-11-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 149 154 - T 01-11-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 PRINTS PR00839 V8 serine protease family signature 169 181 2.2E-24 T 01-11-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 PRINTS PR00839 V8 serine protease family signature 138 155 2.2E-24 T 01-11-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 PRINTS PR00839 V8 serine protease family signature 109 126 2.2E-24 T 01-11-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 PRINTS PR00839 V8 serine protease family signature 231 244 2.2E-24 T 01-11-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 PRINTS PR00839 V8 serine protease family signature 267 283 2.2E-24 T 01-11-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 PRINTS PR00839 V8 serine protease family signature 288 300 2.2E-24 T 01-11-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 SUPERFAMILY SSF50494 98 320 5.77E-32 T 01-11-2018 IPR009003 Peptidase S1, PA clan MLA2C4_04240 a288a4d56a108444b65176e5eb1ae8fa 323 Gene3D G3DSA:2.40.10.10 104 301 5.8E-61 T 01-11-2018 MLA2C4_14255 8f153a8dc5d9c1a276b18dd6d00bc3d5 338 Gene3D G3DSA:3.40.710.10 4 317 8.3E-51 T 01-11-2018 MLA2C4_14255 8f153a8dc5d9c1a276b18dd6d00bc3d5 338 SUPERFAMILY SSF56601 4 320 6.88E-53 T 01-11-2018 IPR012338 Beta-lactamase/transpeptidase-like MLA2C4_14255 8f153a8dc5d9c1a276b18dd6d00bc3d5 338 Pfam PF00144 Beta-lactamase 10 316 1.9E-34 T 01-11-2018 IPR001466 Beta-lactamase-related MLA2C4_10495 ecd1ff7260c1915c3f8271c114e6239a 491 SUPERFAMILY SSF75304 12 487 5.89E-102 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_10495 ecd1ff7260c1915c3f8271c114e6239a 491 Pfam PF01425 Amidase 31 469 9.7E-76 T 01-11-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_10495 ecd1ff7260c1915c3f8271c114e6239a 491 Gene3D G3DSA:3.90.1300.10 1 490 2.9E-166 T 01-11-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MLA2C4_17650 9b877058d5119f63ad860d22892b8af1 137 Pfam PF03899 ATP synthase I chain 9 102 2.0E-12 T 01-11-2018 IPR005598 ATP synthase protein I MLA2C4_17650 9b877058d5119f63ad860d22892b8af1 137 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 124 2.0E-45 T 01-11-2018 MLA2C4_27140 ebd379094a89d5bf5d395f3c5afdcf4f 74 Pfam PF07872 Protein of unknown function (DUF1659) 8 51 1.9E-14 T 01-11-2018 IPR012454 Protein of unknown function DUF1659 MLA2C4_14105 cba05fdaf707026b5a42b9e711e3984b 266 Pfam PF02361 Cobalt transport protein 4 222 7.4E-28 T 01-11-2018 IPR003339 ABC/ECF transporter, transmembrane component MLA2C4_25185 924fcfdf7516f49b57e8705ad0a68cef 250 SMART SM00382 32 220 1.6E-10 T 01-11-2018 IPR003593 AAA+ ATPase domain MLA2C4_25185 924fcfdf7516f49b57e8705ad0a68cef 250 Pfam PF00005 ABC transporter 23 171 3.8E-34 T 01-11-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MLA2C4_25185 924fcfdf7516f49b57e8705ad0a68cef 250 SUPERFAMILY SSF52540 4 224 6.75E-66 T 01-11-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MLA2C4_25185 924fcfdf7516f49b57e8705ad0a68cef 250 Gene3D G3DSA:3.40.50.300 1 240 2.7E-66 T 01-11-2018 MLA2C4_04825 e1e9bf98f336ac8eaf1eb77bf66d8694 459 Pfam PF13425 O-antigen ligase like membrane protein 10 458 2.3E-132 T 01-11-2018 MLA2C4_24515 08ad7a8c505a4260a0285a8012922094 75 Pfam PF13119 Domain of unknown function (DUF3973) 1 40 1.7E-29 T 01-11-2018 IPR025003 Domain of unknown function DUF3973 MLA2C4_16200 771eb4b51a96ce13580aa949d61c7f45 225 Gene3D G3DSA:3.20.20.380 1 225 5.1E-86 T 01-11-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 MLA2C4_16200 771eb4b51a96ce13580aa949d61c7f45 225 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 1 203 25.75 T 01-11-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 MLA2C4_16200 771eb4b51a96ce13580aa949d61c7f45 225 Pfam PF03932 CutC family 2 199 1.3E-55 T 01-11-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 MLA2C4_16200 771eb4b51a96ce13580aa949d61c7f45 225 SUPERFAMILY SSF110395 1 224 3.14E-61 T 01-11-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 MLA2C4_16430 419768d8e36ab0cfd21991d547cdec1e 524 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 44 513 4.1E-188 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_16430 419768d8e36ab0cfd21991d547cdec1e 524 PIRSF PIRSF005690 29 524 5.1E-190 T 01-11-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 MLA2C4_15290 0525924526949120e6f91c1f12d0b241 321 Gene3D G3DSA:3.90.245.10 5 319 6.1E-71 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_15290 0525924526949120e6f91c1f12d0b241 321 SUPERFAMILY SSF53590 6 315 1.83E-78 T 01-11-2018 IPR036452 Ribonucleoside hydrolase-like MLA2C4_15290 0525924526949120e6f91c1f12d0b241 321 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 6 308 3.5E-62 T 01-11-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MLA2C4_20885 1ae227ed7bbaced40df128dcb75a7158 152 Pfam PF14177 YkyB-like protein 16 137 3.5E-56 T 01-11-2018 IPR025552 YkyB-like protein MLA2C4_01045 72da094b624bd348aed760868dc64441 177 SUPERFAMILY SSF103473 8 172 1.7E-24 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_01045 72da094b624bd348aed760868dc64441 177 Gene3D G3DSA:1.20.1250.20 2 176 1.7E-25 T 01-11-2018 MLA2C4_01045 72da094b624bd348aed760868dc64441 177 Pfam PF07690 Major Facilitator Superfamily 9 171 3.1E-19 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_25845 72d601065be00a6840c81fbc8e2bce02 192 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 12 168 2.6E-21 T 01-11-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like MLA2C4_04460 f3d6b47cbc95bf01470c523b9fd7e52f 114 Pfam PF13157 Protein of unknown function (DUF3992) 21 109 2.2E-34 T 01-11-2018 IPR025055 Protein of unknown function DUF3992 MLA2C4_17205 f4534294f520e499192200c8104ef3a5 110 Pfam PF13034 Protein of unknown function (DUF3895) 28 102 2.0E-35 T 01-11-2018 IPR024995 Protein of unknown function DUF3895 MLA2C4_06435 1b77f3ade7c8909ecbf297f411595234 140 Pfam PF13673 Acetyltransferase (GNAT) domain 21 140 4.0E-21 T 01-11-2018 IPR000182 GNAT domain MLA2C4_06435 1b77f3ade7c8909ecbf297f411595234 140 SUPERFAMILY SSF55729 4 140 3.71E-37 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_06435 1b77f3ade7c8909ecbf297f411595234 140 Gene3D G3DSA:3.40.630.30 2 139 9.5E-44 T 01-11-2018 MLA2C4_00255 c4e6c2294b1c7b46e0ca05d34d3ab32f 52 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 6 15 - T 01-11-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 MLA2C4_00255 c4e6c2294b1c7b46e0ca05d34d3ab32f 52 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 3 47 2.6E-7 T 01-11-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 MLA2C4_11820 890da6f35f63ce039344e7f0d127cdf8 158 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 20 103 4.8E-7 T 01-11-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component MLA2C4_20740 699d5c2918ecbf66fef2f82152249da1 405 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 114 245 6.4E-13 T 01-11-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain MLA2C4_18095 1b5c2fa3ba23d9663620988107bebedc 138 Pfam PF10901 Protein of unknown function (DUF2690) 15 119 1.4E-35 T 01-11-2018 IPR021224 Protein of unknown function DUF2690 MLA2C4_19820 28c311c10fb1cfe158de6b393fd1638f 352 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 334 4.5E-43 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_01990 82a5965b6065f1438880ee77d17b9df6 235 Gene3D G3DSA:3.30.2010.10 135 230 4.4E-17 T 01-11-2018 MLA2C4_01990 82a5965b6065f1438880ee77d17b9df6 235 Pfam PF01863 Protein of unknown function DUF45 20 227 1.3E-61 T 01-11-2018 IPR002725 Protein of unknown function DUF45 MLA2C4_05085 4196c51333f2ad45107fe29a907624e7 36 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 1.3E-11 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_05085 4196c51333f2ad45107fe29a907624e7 36 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 11 33 2.7E-12 T 01-11-2018 IPR010070 Sporulation protein YjcZ-like MLA2C4_11110 240501d7f5947b9ae0de77907fae544a 479 Pfam PF02447 GntP family permease 65 271 5.6E-9 T 01-11-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MLA2C4_08515 aa799c7dee6c963187f487be44e62ad8 277 Pfam PF01618 MotA/TolQ/ExbB proton channel family 121 237 4.4E-24 T 01-11-2018 IPR002898 MotA/TolQ/ExbB proton channel MLA2C4_08515 aa799c7dee6c963187f487be44e62ad8 277 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 01-11-2018 IPR000540 Flagellar motor protein MotA, conserved site MLA2C4_08240 b35d2cd77e170dc00e808d84420a4f9a 387 Pfam PF04235 Protein of unknown function (DUF418) 217 376 2.8E-39 T 01-11-2018 IPR007349 Domain of unknown function DUF418 MLA2C4_17745 6cf62fa581f6951a0640460cb97be4c7 439 Pfam PF03222 Tryptophan/tyrosine permease family 40 406 2.3E-16 T 01-11-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MLA2C4_15030 fabf757fed22740cbfe7275d2a391840 254 Pfam PF08876 Domain of unknown function (DUF1836) 70 166 2.8E-16 T 01-11-2018 IPR014975 Protein of unknown function DUF1836 MLA2C4_13580 b866fe6c962f14025b0a4b7edea128b7 282 Pfam PF04203 Sortase family 114 239 1.4E-25 T 01-11-2018 IPR005754 Sortase family MLA2C4_13580 b866fe6c962f14025b0a4b7edea128b7 282 SUPERFAMILY SSF63817 32 240 2.35E-47 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_13580 b866fe6c962f14025b0a4b7edea128b7 282 TIGRFAM TIGR01076 sortase_fam: sortase 112 245 1.0E-51 T 01-11-2018 IPR005754 Sortase family MLA2C4_13580 b866fe6c962f14025b0a4b7edea128b7 282 Gene3D G3DSA:2.40.260.10 44 256 9.6E-69 T 01-11-2018 IPR023365 Sortase domain superfamily MLA2C4_27310 9dc8f05d9017225130eb2748d91344c2 247 Pfam PF13807 G-rich domain on putative tyrosine kinase 144 194 1.7E-8 T 01-11-2018 IPR032807 Tyrosine kinase, G-rich domain MLA2C4_27310 9dc8f05d9017225130eb2748d91344c2 247 Pfam PF02706 Chain length determinant protein 3 93 2.5E-21 T 01-11-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MLA2C4_28195 33a70d9617d728fb3afa422d0dcd8aa1 522 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 12 493 7.9E-148 T 01-11-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MLA2C4_20825 9fc1d1537f846c80663b927dda38057c 63 ProDom PD054279 YKZF 20 58 0.001 T 01-11-2018 MLA2C4_20825 9fc1d1537f846c80663b927dda38057c 63 Pfam PF14156 Antirepressor AbbA 1 61 1.5E-29 T 01-11-2018 IPR025446 Antirepressor AbbA MLA2C4_09550 78ee469127e202e5dc11cb0869f99c74 176 SUPERFAMILY SSF55729 1 174 1.18E-50 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_09550 78ee469127e202e5dc11cb0869f99c74 176 Gene3D G3DSA:3.40.630.30 3 174 1.8E-48 T 01-11-2018 MLA2C4_09550 78ee469127e202e5dc11cb0869f99c74 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 6.2E-33 T 01-11-2018 IPR000182 GNAT domain MLA2C4_10590 30a228ddc60064955b0ea4cfc6f6236e 281 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 209 1.7E-54 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_10590 30a228ddc60064955b0ea4cfc6f6236e 281 PIRSF PIRSF006483 1 275 1.7E-67 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_10590 30a228ddc60064955b0ea4cfc6f6236e 281 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 267 8.1E-13 T 01-11-2018 IPR019264 Domain of unknown function DUF2179 MLA2C4_10590 30a228ddc60064955b0ea4cfc6f6236e 281 Gene3D G3DSA:3.30.70.120 187 261 4.6E-20 T 01-11-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MLA2C4_10145 1f7705115daf2fee64371a4751df0a07 250 Pfam PF09234 Domain of unknown function (DUF1963) 44 248 5.6E-38 T 01-11-2018 IPR015315 Protein of unknown function DUF1963 MLA2C4_10145 1f7705115daf2fee64371a4751df0a07 250 SUPERFAMILY SSF103032 15 250 7.19E-60 T 01-11-2018 IPR035948 YwqG-like superfamily MLA2C4_10145 1f7705115daf2fee64371a4751df0a07 250 Gene3D G3DSA:2.30.320.10 9 248 1.7E-36 T 01-11-2018 IPR035948 YwqG-like superfamily MLA2C4_17445 618036bcd747c0271df7ace1cc94d3c4 93 Pfam PF06949 Protein of unknown function (DUF1292) 17 88 1.5E-11 T 01-11-2018 IPR009711 Uncharacterised protein family UPF0473 MLA2C4_25120 9bc12ad0d9b9710e0fcbfb41aceb30eb 199 Pfam PF09335 SNARE associated Golgi protein 31 155 2.8E-23 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_27405 d010d6f0ff6027e056893d40e49ef84e 174 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 1.7E-34 T 01-11-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MLA2C4_27405 d010d6f0ff6027e056893d40e49ef84e 174 Gene3D G3DSA:1.20.120.1200 5 166 9.1E-38 T 01-11-2018 MLA2C4_26950 2edd3021393d48856eb3b04ddaf5d5d8 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 8.5E-23 T 01-11-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MLA2C4_26950 2edd3021393d48856eb3b04ddaf5d5d8 100 Gene3D G3DSA:3.40.50.2300 1 100 2.1E-41 T 01-11-2018 MLA2C4_26950 2edd3021393d48856eb3b04ddaf5d5d8 100 SUPERFAMILY SSF52794 1 99 4.45E-35 T 01-11-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 MLA2C4_02775 1336883b34b31683e20a36acfb8f147b 134 SUPERFAMILY SSF81324 14 123 7.59E-12 T 01-11-2018 MLA2C4_02775 1336883b34b31683e20a36acfb8f147b 134 Pfam PF07885 Ion channel 44 126 1.3E-12 T 01-11-2018 IPR013099 Potassium channel domain MLA2C4_02775 1336883b34b31683e20a36acfb8f147b 134 Gene3D G3DSA:1.10.287.70 21 132 1.7E-12 T 01-11-2018 MLA2C4_12700 f6ef4f4d71d141bce197a2ce00ab81a0 380 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 217 380 3.0E-64 T 01-11-2018 IPR021210 Exosporium BclB, C-terminal MLA2C4_16295 f754d0cb826862a7057824d698a2f0c3 405 Pfam PF12051 Protein of unknown function (DUF3533) 27 375 5.7E-27 T 01-11-2018 IPR022703 Domain of unknown function DUF3533 MLA2C4_14275 4a68524a8d605d6c12a344819b0fb4e7 171 SUPERFAMILY SSF109854 7 165 4.73E-26 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_14275 4a68524a8d605d6c12a344819b0fb4e7 171 Gene3D G3DSA:1.20.120.450 2 165 2.7E-34 T 01-11-2018 IPR034660 DinB/YfiT-like putative metalloenzymes MLA2C4_14275 4a68524a8d605d6c12a344819b0fb4e7 171 Pfam PF12867 DinB superfamily 9 160 3.4E-15 T 01-11-2018 IPR024775 DinB-like domain MLA2C4_03310 5399d343fc444ff55393365b3ae7e382 465 Pfam PF13520 Amino acid permease 7 429 2.9E-52 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_03310 5399d343fc444ff55393365b3ae7e382 465 Gene3D G3DSA:1.20.1740.10 1 465 1.1E-61 T 01-11-2018 MLA2C4_03310 5399d343fc444ff55393365b3ae7e382 465 PIRSF PIRSF006060 1 465 5.5E-55 T 01-11-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MLA2C4_05745 f772f9c0550e9b32d4ca08a916b667f2 632 Pfam PF05569 BlaR1 peptidase M56 17 327 1.1E-60 T 01-11-2018 IPR008756 Peptidase M56 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 295 316 2.6E-37 T 01-11-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 221 238 2.6E-37 T 01-11-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 265 280 2.6E-37 T 01-11-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 7 29 2.6E-37 T 01-11-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 201 219 2.6E-37 T 01-11-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 Gene3D G3DSA:3.40.1690.10 211 347 2.1E-47 T 01-11-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 339 9.2E-111 T 01-11-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MLA2C4_08720 a8e0d9f237207330d32833555fcca8d5 348 SUPERFAMILY SSF160544 237 344 4.19E-33 T 01-11-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MLA2C4_04410 54eec45874c879256cc41d3bc628c6af 438 Pfam PF05525 Branched-chain amino acid transport protein 8 428 5.3E-140 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_04410 54eec45874c879256cc41d3bc628c6af 438 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 415 7.5E-128 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_09095 fa5254ff0af19765dbc56c2b19a7024a 369 Pfam PF12698 ABC-2 family transporter protein 19 360 2.2E-30 T 01-11-2018 MLA2C4_16465 70c3c95db48d62206bf6c3a1c329de62 383 Pfam PF03600 Citrate transporter 24 308 6.2E-17 T 01-11-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MLA2C4_21025 e243970e79ed53fac51e1683182901af 242 Pfam PF13803 Domain of unknown function (DUF4184) 1 236 1.3E-73 T 01-11-2018 IPR025238 Protein of unknown function DUF4184 MLA2C4_24520 1bdebf3c02b0d96dbf33aeb80f331071 60 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 6.0E-27 T 01-11-2018 IPR020296 Sporulation protein Cse60 MLA2C4_24520 1bdebf3c02b0d96dbf33aeb80f331071 60 Pfam PF10957 Sporulation protein Cse60 1 60 4.8E-35 T 01-11-2018 IPR020296 Sporulation protein Cse60 MLA2C4_26630 a902719ed2a47b37e96e756e128569dd 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 4.3E-51 T 01-11-2018 IPR014204 Sporulation stage V, protein AE MLA2C4_26630 a902719ed2a47b37e96e756e128569dd 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 110 7.1E-40 T 01-11-2018 IPR005562 SpoVA MLA2C4_08980 0cb6b0967fbcebcb6086f8a0ff7f8d72 140 Pfam PF06713 Bacterial PH domain 54 128 2.1E-19 T 01-11-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 MLA2C4_12650 f7885f4fe4e4a2fc31a87aca536c17be 194 Pfam PF13814 Replication-relaxation 4 161 1.7E-17 T 01-11-2018 IPR025855 Plasmid replication-relaxation MLA2C4_04430 80c6db844b3a0d0fbcc347ce1e5ffdbb 137 Gene3D G3DSA:3.10.180.10 23 136 5.8E-13 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_04430 80c6db844b3a0d0fbcc347ce1e5ffdbb 137 SUPERFAMILY SSF54593 25 136 8.8E-13 T 01-11-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MLA2C4_02105 31db5dc303f8aa86ad30245c161d4968 222 ProDom PD210561 YWRJ 1 222 2.0E-124 T 01-11-2018 IPR020173 Uncharacterised protein family YwrJ MLA2C4_21880 5f8bc65e61b5067f695fa56a99366525 130 Pfam PF03780 Asp23 family, cell envelope-related function 14 118 6.1E-36 T 01-11-2018 IPR005531 Alkaline shock protein Asp23 MLA2C4_21980 6214bc951286e86b9b69520827e9d3b4 133 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 4 133 2.0E-12 T 01-11-2018 MLA2C4_13210 969cf5f153b7605c69d8592777be9025 111 Pfam PF06356 Protein of unknown function (DUF1064) 8 108 5.0E-31 T 01-11-2018 IPR009414 Protein of unknown function DUF1064 MLA2C4_15365 19b4ee3e3abea89a5c60fd606b241eac 223 Pfam PF13261 Protein of unknown function (DUF4052) 4 220 1.7E-111 T 01-11-2018 IPR025126 Protein of unknown function DUF4052 MLA2C4_20155 12735c161ce06f6a7e5033384d4a5747 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 8.7E-37 T 01-11-2018 IPR005531 Alkaline shock protein Asp23 MLA2C4_19035 e66218a8f0160d9ac6744b8e0cb50671 168 Pfam PF07301 Protein of unknown function (DUF1453) 6 149 2.6E-61 T 01-11-2018 IPR009916 Protein of unknown function DUF1453 MLA2C4_19035 e66218a8f0160d9ac6744b8e0cb50671 168 PIRSF PIRSF021441 1 161 8.9E-73 T 01-11-2018 IPR031306 CcdC protein MLA2C4_05125 57cc247e8c057dc12aa75cb65bdf02bf 123 Pfam PF03899 ATP synthase I chain 10 103 2.6E-14 T 01-11-2018 IPR005598 ATP synthase protein I MLA2C4_05125 57cc247e8c057dc12aa75cb65bdf02bf 123 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 123 4.0E-53 T 01-11-2018 MLA2C4_09495 f732c400913da6b53c00e8bf9a2534b9 253 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 244 6.8E-42 T 01-11-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MLA2C4_09495 f732c400913da6b53c00e8bf9a2534b9 253 SUPERFAMILY SSF53213 1 253 1.83E-80 T 01-11-2018 MLA2C4_09495 f732c400913da6b53c00e8bf9a2534b9 253 Gene3D G3DSA:3.40.830.10 1 253 1.3E-84 T 01-11-2018 MLA2C4_09495 f732c400913da6b53c00e8bf9a2534b9 253 PIRSF PIRSF006157 1 253 7.4E-96 T 01-11-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 MLA2C4_18740 f738b35eb31c0942c4f603490ea0c288 44 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 44 15.192 T 01-11-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 MLA2C4_18740 f738b35eb31c0942c4f603490ea0c288 44 Pfam PF08177 Small acid-soluble spore protein N family 1 43 1.8E-21 T 01-11-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 MLA2C4_15810 9fbda58c2d40139e1148ee759ba1310a 128 Pfam PF13026 Protein of unknown function (DUF3887) 37 125 6.3E-19 T 01-11-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 MLA2C4_15810 9fbda58c2d40139e1148ee759ba1310a 128 Gene3D G3DSA:3.10.450.590 23 126 3.2E-14 T 01-11-2018 MLA2C4_03280 943e0348ee9328e2687d64c9da172d83 627 Gene3D G3DSA:3.40.50.410 424 622 3.9E-10 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily MLA2C4_03280 943e0348ee9328e2687d64c9da172d83 627 Pfam PF00092 von Willebrand factor type A domain 436 601 9.8E-6 T 01-11-2018 IPR002035 von Willebrand factor, type A MLA2C4_03280 943e0348ee9328e2687d64c9da172d83 627 SUPERFAMILY SSF53300 435 621 7.71E-15 T 01-11-2018 IPR036465 von Willebrand factor A-like domain superfamily MLA2C4_03280 943e0348ee9328e2687d64c9da172d83 627 SMART SM00327 431 622 1.2E-9 T 01-11-2018 IPR002035 von Willebrand factor, type A MLA2C4_01720 ab79b1e72d07ca684c76e2499a62ae42 306 Pfam PF00892 EamA-like transporter family 2 136 4.5E-23 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_01720 ab79b1e72d07ca684c76e2499a62ae42 306 Pfam PF00892 EamA-like transporter family 149 284 1.1E-19 T 01-11-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MLA2C4_01720 ab79b1e72d07ca684c76e2499a62ae42 306 SUPERFAMILY SSF103481 186 286 1.57E-14 T 01-11-2018 MLA2C4_01720 ab79b1e72d07ca684c76e2499a62ae42 306 SUPERFAMILY SSF103481 39 140 7.32E-15 T 01-11-2018 MLA2C4_27380 787dfd5747427b56d9626beeefcec3e0 78 Pfam PF06612 Protein of unknown function (DUF1146) 17 64 1.9E-21 T 01-11-2018 IPR009526 Protein of unknown function DUF1146 MLA2C4_27380 787dfd5747427b56d9626beeefcec3e0 78 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 76 5.3E-33 T 01-11-2018 IPR009526 Protein of unknown function DUF1146 MLA2C4_20040 98d1d28a4f6fe3160af32e684c67208d 289 SUPERFAMILY SSF102405 80 287 1.53E-33 T 01-11-2018 MLA2C4_20040 98d1d28a4f6fe3160af32e684c67208d 289 Gene3D G3DSA:3.40.50.450 19 288 4.4E-90 T 01-11-2018 MLA2C4_20040 98d1d28a4f6fe3160af32e684c67208d 289 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 286 1.2E-70 T 01-11-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MLA2C4_20040 98d1d28a4f6fe3160af32e684c67208d 289 Pfam PF02481 DNA recombination-mediator protein A 71 278 1.1E-75 T 01-11-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MLA2C4_07475 d8fa0e4d43253f32aa3b4591c1492ae5 55 Pfam PF13217 Protein of unknown function (DUF4025) 4 48 1.4E-15 T 01-11-2018 IPR025100 Protein of unknown function DUF4025 MLA2C4_21975 196e967671337a4e78a5dca669541825 306 Pfam PF07136 Protein of unknown function (DUF1385) 56 300 1.0E-78 T 01-11-2018 IPR010787 Protein of unknown function DUF1385 MLA2C4_21975 196e967671337a4e78a5dca669541825 306 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 56 297 3.0E-138 T 01-11-2018 IPR010787 Protein of unknown function DUF1385 MLA2C4_21635 66c910de3843b7f5d4d7a3aac9ae5204 317 Pfam PF00753 Metallo-beta-lactamase superfamily 17 231 5.6E-23 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_21635 66c910de3843b7f5d4d7a3aac9ae5204 317 Gene3D G3DSA:3.60.15.10 1 259 8.1E-51 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_21635 66c910de3843b7f5d4d7a3aac9ae5204 317 SMART SM00849 17 231 1.4E-22 T 01-11-2018 IPR001279 Metallo-beta-lactamase MLA2C4_21635 66c910de3843b7f5d4d7a3aac9ae5204 317 SUPERFAMILY SSF56281 4 297 1.44E-44 T 01-11-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MLA2C4_11150 98d5026c55c95f6044f943afd3d51d9a 399 Pfam PF05975 Bacterial ABC transporter protein EcsB 4 388 4.6E-63 T 01-11-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 MLA2C4_13800 659d3c784eea0bcbd01c5c0a17007f93 142 Gene3D G3DSA:1.10.10.2520 8 92 1.4E-12 T 01-11-2018 MLA2C4_13800 659d3c784eea0bcbd01c5c0a17007f93 142 Pfam PF07486 Cell Wall Hydrolase 24 129 4.3E-15 T 01-11-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 MLA2C4_15660 8739ee59876965afbfcc1a1839755296 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 304 2.0E-47 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_12530 760909362b9538616b92fec63164f607 261 Pfam PF03567 Sulfotransferase family 21 254 3.1E-6 T 01-11-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 MLA2C4_16235 a46b9c0ca5b76c9413b0d0f7a4c26034 292 Pfam PF13649 Methyltransferase domain 61 158 7.4E-18 T 01-11-2018 MLA2C4_16235 a46b9c0ca5b76c9413b0d0f7a4c26034 292 Gene3D G3DSA:3.40.50.150 24 220 3.8E-30 T 01-11-2018 MLA2C4_16235 a46b9c0ca5b76c9413b0d0f7a4c26034 292 SUPERFAMILY SSF53335 25 239 5.68E-32 T 01-11-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MLA2C4_04245 0c02785ccf2e996446dbb16c308ab246 128 Pfam PF10794 Protein of unknown function (DUF2606) 1 126 8.4E-51 T 01-11-2018 IPR019730 Protein of unknown function DUF2606 MLA2C4_24080 3d1e4e47100674453520f0707d5b6a98 277 Pfam PF12787 EcsC protein family 8 270 3.1E-58 T 01-11-2018 IPR024787 EcsC protein MLA2C4_24080 3d1e4e47100674453520f0707d5b6a98 277 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 59 273 3.0E-6 T 01-11-2018 MLA2C4_24905 8d435f649dde56f00c9a8c48cb6c6168 179 Pfam PF11667 Putative zincin peptidase 58 163 2.2E-22 T 01-11-2018 IPR021683 Putative zincin peptidase MLA2C4_22830 d2037a5b14998327863e231ae4af8100 71 Pfam PF10750 Protein of unknown function (DUF2536) 2 68 2.6E-36 T 01-11-2018 IPR019686 Protein of unknown function DUF2536 MLA2C4_24525 9011e17906dc851cfe89b8fcad0b9693 78 Pfam PF10830 Protein of unknown function (DUF2553) 6 78 1.1E-17 T 01-11-2018 IPR020140 Uncharacterised protein family YusG MLA2C4_24525 9011e17906dc851cfe89b8fcad0b9693 78 ProDom PD058325 YUSG BH3483 1 78 4.0E-39 T 01-11-2018 IPR020140 Uncharacterised protein family YusG MLA2C4_06985 7a8ac3ccf1109738d0eaf50a54b5e408 160 TIGRFAM TIGR02132 phaR_Bmeg: polyhydroxyalkanoic acid synthase, PhaR subunit 2 135 1.6E-75 T 01-11-2018 IPR011729 Polyhydroxyalkanoic acid synthase, PhaR subunit MLA2C4_13980 1e0ac65c8679bceb722439db80bf0b5f 795 Pfam PF13032 Domain of unknown function (DUF3893) 658 765 2.5E-17 T 01-11-2018 IPR024996 Domain of unknown function DUF3893 MLA2C4_13980 1e0ac65c8679bceb722439db80bf0b5f 795 Pfam PF13111 Protein of unknown function (DUF3962) 6 216 4.0E-95 T 01-11-2018 IPR025085 Domain of unknown function DUF3962 MLA2C4_15255 e96356a744bd86525dd1ffcf535fc514 207 Pfam PF13171 Protein of unknown function (DUF4004) 4 199 8.6E-86 T 01-11-2018 IPR025063 Protein of unknown function DUF4004 MLA2C4_05095 ab82b7e77469561d0fa3608ae7986d62 118 Pfam PF14078 Domain of unknown function (DUF4259) 2 100 1.2E-4 T 01-11-2018 IPR025355 Protein of unknown function DUF4259 MLA2C4_14195 accc26785c43314daf90b45f7203c17f 214 Pfam PF06966 Protein of unknown function (DUF1295) 80 206 2.2E-16 T 01-11-2018 IPR010721 Protein of unknown function DUF1295 MLA2C4_14195 accc26785c43314daf90b45f7203c17f 214 Gene3D G3DSA:1.20.120.1630 56 213 2.0E-15 T 01-11-2018 MLA2C4_13925 024c705f4e8b8fe5b82227e9c2f851e5 17 Pfam PF10668 Phage terminase small subunit 1 15 4.2E-5 T 01-11-2018 IPR018925 Phage terminase small subunit MLA2C4_15490 e020832db37c9d7c7375e54662ee6897 312 Pfam PF13536 Putative multidrug resistance efflux transporter 38 297 9.8E-108 T 01-11-2018 IPR032713 Putative multidrug resistance efflux transporter MLA2C4_04205 8ee9fb691c465510c380f0a9498f2638 255 Pfam PF10137 Predicted nucleotide-binding protein containing TIR-like domain 109 231 2.7E-35 T 01-11-2018 IPR019302 Nucleotide-binding protein, predicted, TIR-like domain MLA2C4_08950 ff8b3f5029c1ac81b36c9bfbd1b7626f 56 Pfam PF13076 Fur-regulated basic protein A 12 46 3.0E-17 T 01-11-2018 IPR025072 Fur-regulated basic protein A MLA2C4_04545 71b3bf8caad0210c513dd5ba82c99e84 151 Gene3D G3DSA:3.40.630.30 3 142 8.4E-29 T 01-11-2018 MLA2C4_04545 71b3bf8caad0210c513dd5ba82c99e84 151 Pfam PF00583 Acetyltransferase (GNAT) family 40 116 8.0E-13 T 01-11-2018 IPR000182 GNAT domain MLA2C4_04545 71b3bf8caad0210c513dd5ba82c99e84 151 SUPERFAMILY SSF55729 1 149 3.82E-22 T 01-11-2018 IPR016181 Acyl-CoA N-acyltransferase MLA2C4_21255 84a7576a55a0367d2c939b88bb824fb4 288 Pfam PF06207 Protein of unknown function (DUF1002) 34 251 3.8E-77 T 01-11-2018 IPR009343 Protein of unknown function DUF1002 MLA2C4_00850 dcb31bc4eda9b508c0c7fc059143e1db 142 Pfam PF10730 Protein of unknown function (DUF2521) 1 142 4.3E-55 T 01-11-2018 IPR019667 Uncharacterised protein family YbaK MLA2C4_08770 b248a6b855f1fbb99444505206c6429d 132 Pfam PF17329 Family of unknown function (DUF5367) 40 129 7.6E-6 T 01-11-2018 IPR020509 Uncharacterised protein family YnzE MLA2C4_08770 b248a6b855f1fbb99444505206c6429d 132 ProDom PD068105 YNZE MEMBRANE TRANSMEMBRANE 31 130 5.0E-39 T 01-11-2018 IPR020509 Uncharacterised protein family YnzE MLA2C4_22145 36e4fe5b652b2b16136922da826effb3 66 Pfam PF14038 YqzE-like protein 2 55 5.0E-28 T 01-11-2018 IPR025622 YqzE-like protein MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 340 8.6E-29 T 01-11-2018 IPR005145 Putative GTP-binding controlling metal-binding domain MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 213 2.7E-65 T 01-11-2018 IPR006070 YrdC-like domain GO:0003725 MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 SUPERFAMILY SSF55821 19 214 8.24E-68 T 01-11-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 Gene3D G3DSA:3.40.50.11030 221 346 1.6E-41 T 01-11-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 Gene3D G3DSA:3.90.870.10 7 218 2.9E-85 T 01-11-2018 MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 Pfam PF01300 Telomere recombination 27 202 1.2E-58 T 01-11-2018 IPR006070 YrdC-like domain GO:0003725 MLA2C4_27565 c4414eed10c94b5cd8bee987073e8b40 346 PIRSF PIRSF004930 1 346 5.6E-135 T 01-11-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 MLA2C4_26550 2dce0434a20002dc658e7eeaf7cf13d7 230 Pfam PF04172 LrgB-like family 14 226 2.6E-65 T 01-11-2018 IPR007300 CidB/LrgB family MLA2C4_24295 b0bc7617340f85869b224b6272179f91 78 Pfam PF13133 Protein of unknown function (DUF3949) 15 75 5.4E-33 T 01-11-2018 IPR025032 Protein of unknown function DUF3949 MLA2C4_03190 d6e83152858dcf8543f7206c09ae5f99 420 Pfam PF04294 VanW like protein 238 366 4.1E-45 T 01-11-2018 IPR007391 Vancomycin resistance VanW MLA2C4_03190 d6e83152858dcf8543f7206c09ae5f99 420 Pfam PF12229 Putative peptidoglycan binding domain 87 199 1.9E-10 T 01-11-2018 IPR022029 Putative peptidoglycan binding domain MLA2C4_27105 16f5beb9a0da64198fa09093bf16fbee 100 Pfam PF13049 Protein of unknown function (DUF3910) 1 93 3.7E-62 T 01-11-2018 IPR025021 Protein of unknown function DUF3910 MLA2C4_16710 062030ed87f1f108c5948bf4c7336c9d 66 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 2.3E-20 T 01-11-2018 IPR012452 Protein of unknown function DUF1657 MLA2C4_20670 4f3f253b4a588508968331f3a5a71d60 59 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 1 56 4.0E-11 T 01-11-2018 IPR035211 Protein of unknown function DUF5325 MLA2C4_20670 4f3f253b4a588508968331f3a5a71d60 59 Pfam PF17259 Family of unknown function (DUF5325) 1 57 1.7E-20 T 01-11-2018 IPR035211 Protein of unknown function DUF5325 MLA2C4_17635 1d323381199eb5501bfa206b9b5ef51a 75 Pfam PF13061 Protein of unknown function (DUF3923) 5 68 2.4E-23 T 01-11-2018 IPR025037 Protein of unknown function DUF3923 MLA2C4_17365 5651087873b14ee897f8dceadc7778ec 403 Gene3D G3DSA:1.20.1250.20 2 391 3.9E-40 T 01-11-2018 MLA2C4_17365 5651087873b14ee897f8dceadc7778ec 403 SUPERFAMILY SSF103473 6 388 1.96E-47 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_17365 5651087873b14ee897f8dceadc7778ec 403 Pfam PF07690 Major Facilitator Superfamily 19 311 8.2E-30 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_10215 4fbbe0528a90756a63813aa5a89d5673 115 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 3 105 2.0E-52 T 01-11-2018 MLA2C4_10215 4fbbe0528a90756a63813aa5a89d5673 115 Pfam PF14074 Protein of unknown function (DUF4257) 6 86 3.5E-31 T 01-11-2018 IPR025353 Protein of unknown function DUF4257) MLA2C4_15520 2706e15ccb04259e8e3e68ed5acb6fda 275 SUPERFAMILY SSF88713 68 266 1.58E-52 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_15520 2706e15ccb04259e8e3e68ed5acb6fda 275 Pfam PF01522 Polysaccharide deacetylase 68 175 6.8E-27 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_15520 2706e15ccb04259e8e3e68ed5acb6fda 275 Gene3D G3DSA:3.20.20.370 32 265 3.7E-63 T 01-11-2018 MLA2C4_10130 71d1adbdaf92368d6b2f2f290a5b4b9e 55 Pfam PF13069 Protein of unknown function (DUF3933) 1 53 8.8E-37 T 01-11-2018 IPR025174 Protein of unknown function DUF3933 MLA2C4_25010 6ca33897aefc2c6094b084058ac58a8e 134 Pfam PF03994 Domain of Unknown Function (DUF350) 12 65 6.0E-6 T 01-11-2018 IPR007140 Protein of unknown function DUF350 MLA2C4_11235 61c27e99875a2045775647a6573e3e7f 83 Pfam PF10751 Protein of unknown function (DUF2535) 2 83 3.6E-26 T 01-11-2018 IPR019687 Protein of unknown function DUF2535 MLA2C4_23945 4743acadd24bbb327245cd7e93096902 87 Pfam PF13133 Protein of unknown function (DUF3949) 19 79 2.5E-31 T 01-11-2018 IPR025032 Protein of unknown function DUF3949 MLA2C4_05980 f07b4c46cc43f14d9e1d995278564f87 197 Pfam PF09335 SNARE associated Golgi protein 43 161 5.1E-25 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_27500 c0025732bbf1d497302edddd3aff514a 74 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 12 64 9.1E-15 T 01-11-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter MLA2C4_09380 87107a1ea5ccdca5f4b0dfda24b1730c 234 Gene3D G3DSA:3.20.20.370 25 234 6.4E-54 T 01-11-2018 MLA2C4_09380 87107a1ea5ccdca5f4b0dfda24b1730c 234 SUPERFAMILY SSF88713 26 229 4.2E-50 T 01-11-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MLA2C4_09380 87107a1ea5ccdca5f4b0dfda24b1730c 234 Pfam PF01522 Polysaccharide deacetylase 42 147 1.0E-28 T 01-11-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MLA2C4_02420 588eef4990a778b16ba17dc6e230d55a 263 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 245 5.5E-80 T 01-11-2018 IPR022493 Integral membrane YkoY MLA2C4_02420 588eef4990a778b16ba17dc6e230d55a 263 Pfam PF03741 Integral membrane protein TerC family 35 216 2.7E-53 T 01-11-2018 IPR005496 Integral membrane protein TerC GO:0016021 MLA2C4_02420 588eef4990a778b16ba17dc6e230d55a 263 SUPERFAMILY SSF103473 30 242 2.09E-6 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_13440 10d612b9cc5b707f94c58de803f776a2 339 Pfam PF01061 ABC-2 type transporter 143 302 2.4E-34 T 01-11-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MLA2C4_04865 cfb367fb504e59a1e6818ba45ee862db 48 Pfam PF11121 Protein of unknown function (DUF2639) 2 38 5.5E-21 T 01-11-2018 IPR022580 Protein of unknown function DUF2639 MLA2C4_04865 cfb367fb504e59a1e6818ba45ee862db 48 ProDom PD049467 YFLJ 1 38 6.0E-15 T 01-11-2018 IPR022580 Protein of unknown function DUF2639 MLA2C4_19285 d40119e2008067b33601c6d3e8f6d815 323 Pfam PF02485 Core-2/I-Branching enzyme 32 292 6.3E-20 T 01-11-2018 IPR003406 Glycosyl transferase, family 14 GO:0008375|GO:0016020 MLA2C4_07575 06e64e045797beb5458b3acf7243d47d 438 Pfam PF03553 Na+/H+ antiporter family 238 421 3.5E-13 T 01-11-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MLA2C4_07575 06e64e045797beb5458b3acf7243d47d 438 Pfam PF03553 Na+/H+ antiporter family 71 210 9.0E-13 T 01-11-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MLA2C4_02700 c63ff77833b0a234ccd0217331d0a7fb 88 Pfam PF14043 WVELL protein 3 75 2.0E-35 T 01-11-2018 IPR026952 WVELL protein MLA2C4_23575 2ba286c6f0c935233e94757662ad5c35 234 Pfam PF12730 ABC-2 family transporter protein 5 181 7.4E-8 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_19240 4a4ffb939bb1a5848c330e9121159783 102 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 28 94 3.3E-14 T 01-11-2018 IPR008792 Coenzyme PQQ synthesis D MLA2C4_00140 32561e7d15cf01417ccc450297bd0e52 73 Pfam PF10704 Protein of unknown function (DUF2508) 1 69 5.8E-27 T 01-11-2018 IPR019644 Protein of unknown function DUF2508 MLA2C4_06125 ef74b25809170b08a3a18537cfd24ed8 43 Pfam PF13081 Domain of unknown function (DUF3941) 18 41 1.5E-13 T 01-11-2018 IPR025077 Protein of unknown function DUF3941 MLA2C4_08760 c631b23ce0febec9f97acdcb0d491e31 56 Pfam PF13131 Protein of unknown function (DUF3951) 1 52 2.4E-28 T 01-11-2018 IPR025028 Protein of unknown function DUF3951 MLA2C4_28175 63ca328f52a5d4b82124ae12460a41ec 143 Pfam PF03788 LrgA family 21 112 1.5E-23 T 01-11-2018 IPR005538 LrgA/CidA family GO:0016021 MLA2C4_26180 41c0f66932e3b3c4597485ecb652c85f 235 Pfam PF11368 Protein of unknown function (DUF3169) 9 228 2.5E-22 T 01-11-2018 IPR021509 Protein of unknown function DUF3169 MLA2C4_11060 681083350b7855febbd2177cc3028ffe 251 Pfam PF06161 Protein of unknown function (DUF975) 150 237 6.9E-23 T 01-11-2018 IPR010380 Protein of unknown function DUF975 MLA2C4_11060 681083350b7855febbd2177cc3028ffe 251 Pfam PF06161 Protein of unknown function (DUF975) 3 156 3.2E-7 T 01-11-2018 IPR010380 Protein of unknown function DUF975 MLA2C4_11030 381b9624388e6bc91ff582adf10d946d 257 Gene3D G3DSA:3.60.40.10 4 255 1.7E-6 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_11030 381b9624388e6bc91ff582adf10d946d 257 SUPERFAMILY SSF81606 33 229 1.96E-6 T 01-11-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MLA2C4_01280 3fc8d9ae2bd9ddf7aa422a2d1fcfb3c2 381 Gene3D G3DSA:3.40.1710.10 43 157 8.6E-7 T 01-11-2018 MLA2C4_01280 3fc8d9ae2bd9ddf7aa422a2d1fcfb3c2 381 Pfam PF12698 ABC-2 family transporter protein 21 375 1.2E-46 T 01-11-2018 MLA2C4_22750 ae411e15cc2d8bc0027397d6a046041e 134 Pfam PF07681 DoxX 7 87 2.8E-21 T 01-11-2018 IPR032808 DoxX family MLA2C4_19715 60de1ee42696fdab6e8729e8a4bb6177 180 Pfam PF10628 Outer spore coat protein E (CotE) 4 175 1.4E-65 T 01-11-2018 IPR018901 Spore coat protein CotE MLA2C4_19765 efba018293dc5ee571daec6d382864ac 207 Gene3D G3DSA:3.40.960.10 107 204 5.8E-20 T 01-11-2018 MLA2C4_26920 a4ecbd84cf01612a03dcce7c8ed47e89 137 Pfam PF07452 CHRD domain 5 132 1.5E-18 T 01-11-2018 IPR010895 CHRD MLA2C4_26920 a4ecbd84cf01612a03dcce7c8ed47e89 137 SMART SM00754 3 134 1.1E-35 T 01-11-2018 IPR010895 CHRD MLA2C4_01200 b7fe8012f0e92e05cd49ccd71bdb284a 31 Pfam PF13134 Protein of unknown function (DUF3948) 1 26 4.4E-13 T 01-11-2018 IPR025034 Protein of unknown function DUF3948 MLA2C4_07660 2ffc4b7f2fbf46e3162d3667dd187b83 266 Pfam PF01925 Sulfite exporter TauE/SafE 7 260 5.1E-57 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MLA2C4_04465 14e0a1bd2faa77c985df016947c2eabe 141 Pfam PF13157 Protein of unknown function (DUF3992) 55 136 9.4E-7 T 01-11-2018 IPR025055 Protein of unknown function DUF3992 MLA2C4_11880 eebaebdc460bcacbefb5bff0761a8db9 189 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 11 151 2.4E-22 T 01-11-2018 IPR018755 Bacteriophage Mu-like, Gp48 MLA2C4_04075 7540075cf38f77284759127ed4bdca59 150 Pfam PF00085 Thioredoxin 58 147 3.1E-16 T 01-11-2018 IPR013766 Thioredoxin domain GO:0045454 MLA2C4_04075 7540075cf38f77284759127ed4bdca59 150 Gene3D G3DSA:3.40.30.10 38 146 4.0E-23 T 01-11-2018 MLA2C4_04075 7540075cf38f77284759127ed4bdca59 150 SUPERFAMILY SSF52833 51 148 2.66E-23 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_02450 6596210c287504de27dfe21b6eccf437 171 Pfam PF13294 Domain of unknown function (DUF4075) 91 169 1.6E-45 T 01-11-2018 IPR025276 Protein of unknown function DUF4075 MLA2C4_16950 75f8055495caf20d12fda01c7a9541a9 331 SUPERFAMILY SSF53686 4 325 1.11E-89 T 01-11-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MLA2C4_16950 75f8055495caf20d12fda01c7a9541a9 331 Gene3D G3DSA:3.40.50.1100 48 156 2.7E-109 T 01-11-2018 MLA2C4_16950 75f8055495caf20d12fda01c7a9541a9 331 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 14 326 2.3E-97 T 01-11-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 MLA2C4_16950 75f8055495caf20d12fda01c7a9541a9 331 Gene3D G3DSA:3.40.50.1100 16 324 2.7E-109 T 01-11-2018 MLA2C4_16950 75f8055495caf20d12fda01c7a9541a9 331 PIRSF PIRSF006278 1 331 1.3E-92 T 01-11-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase MLA2C4_16950 75f8055495caf20d12fda01c7a9541a9 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 318 3.5E-56 T 01-11-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MLA2C4_22230 b365e5bfe0ca80d70a0c01946e5776d9 86 Pfam PF13110 Protein of unknown function (DUF3966) 35 84 1.1E-34 T 01-11-2018 IPR025084 Protein of unknown function DUF3966 MLA2C4_05930 248861f6e13ad543862ed57aaee82448 218 Pfam PF00395 S-layer homology domain 167 209 3.0E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05930 248861f6e13ad543862ed57aaee82448 218 Pfam PF00395 S-layer homology domain 106 150 7.7E-12 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_05930 248861f6e13ad543862ed57aaee82448 218 Pfam PF00395 S-layer homology domain 42 84 1.6E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_19850 b6bbf1ceafdcab403aca0ba0e0503257 67 Pfam PF14035 YlzJ-like protein 3 65 2.7E-21 T 01-11-2018 IPR025619 YlzJ-like protein MLA2C4_27555 884e54b19d28f8c3f09edefed6fc51ce 91 Pfam PF13071 Protein of unknown function (DUF3935) 2 71 3.4E-47 T 01-11-2018 IPR025176 Protein of unknown function DUF3935 MLA2C4_11590 87f82c3c82fa62e18e838995e2a80465 89 Pfam PF12728 Helix-turn-helix domain 35 84 2.4E-11 T 01-11-2018 MLA2C4_27010 fad31423c4158995f14182ac0489ff5d 361 Gene3D G3DSA:1.50.10.10 22 357 6.4E-96 T 01-11-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MLA2C4_27010 fad31423c4158995f14182ac0489ff5d 361 SUPERFAMILY SSF48208 10 348 2.2E-48 T 01-11-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MLA2C4_28270 b62f5c47380f226f08f0f54e28694021 186 Pfam PF08876 Domain of unknown function (DUF1836) 19 123 1.7E-31 T 01-11-2018 IPR014975 Protein of unknown function DUF1836 MLA2C4_15420 5ae16c7fe79bbf2db5fdcbe8b9118b3b 273 Pfam PF14279 HNH endonuclease 4 53 2.4E-13 T 01-11-2018 IPR029471 HNH endonuclease 5 MLA2C4_06005 8dba5304739b3495006e2e3d78ab516b 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 2.2E-24 T 01-11-2018 IPR019618 Spore germination protein GerPA/GerPF MLA2C4_11435 4d8fe8465705c3172cc64b10b1363a81 180 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 180 19.049 T 01-11-2018 IPR023522 Chromosome-anchoring protein RacA MLA2C4_11435 4d8fe8465705c3172cc64b10b1363a81 180 SUPERFAMILY SSF58064 67 145 1.35E-5 T 01-11-2018 MLA2C4_11435 4d8fe8465705c3172cc64b10b1363a81 180 Gene3D G3DSA:1.10.1660.10 4 63 5.4E-10 T 01-11-2018 MLA2C4_18880 68ac2af7aaba63a18e9c11c050ec246c 67 Gene3D G3DSA:2.20.25.10 5 52 1.0E-5 T 01-11-2018 MLA2C4_22725 d1a4793be0ba34eb37ae5ee8bbd88fa7 412 Gene3D G3DSA:2.120.10.30 195 401 5.6E-9 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_22725 d1a4793be0ba34eb37ae5ee8bbd88fa7 412 Gene3D G3DSA:2.120.10.30 27 173 8.5E-11 T 01-11-2018 IPR011042 Six-bladed beta-propeller, TolB-like MLA2C4_22725 d1a4793be0ba34eb37ae5ee8bbd88fa7 412 SUPERFAMILY SSF82171 44 389 3.66E-27 T 01-11-2018 MLA2C4_22725 d1a4793be0ba34eb37ae5ee8bbd88fa7 412 Pfam PF08662 Eukaryotic translation initiation factor eIF2A 46 155 2.9E-5 T 01-11-2018 IPR013979 Translation initiation factor, beta propellor-like domain MLA2C4_19210 25d0dd1f3cb95df51ba27e7bf38331c7 268 Pfam PF13349 Putative adhesin 46 265 2.8E-25 T 01-11-2018 IPR025164 Putative adhesin MLA2C4_20365 dd3c1380208e56c9945d1f3258ae974f 168 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.7E-17 T 01-11-2018 IPR019933 DivIVA domain MLA2C4_20365 dd3c1380208e56c9945d1f3258ae974f 168 Pfam PF05103 DivIVA protein 3 133 6.8E-52 T 01-11-2018 IPR007793 DivIVA family MLA2C4_13275 73af676511ba532aed6ce7cdda07ef74 245 ProDom PD120066 SPORULATION STAGE SA II SPOIISA TRANSMEMBRANE MEMBRANE KILLER 24 156 0.001 T 01-11-2018 MLA2C4_13275 73af676511ba532aed6ce7cdda07ef74 245 Pfam PF14171 Toxin SpoIISA, type II toxin-antitoxin system 9 243 4.6E-70 T 01-11-2018 IPR025940 Toxin SpoIISA, type II toxin-antitoxin system GO:0009405|GO:0016021 MLA2C4_14780 d7ad8ddf38ec726365cd38ba846fb07d 106 Gene3D G3DSA:3.10.20.30 5 92 8.0E-20 T 01-11-2018 IPR012675 Beta-grasp domain superfamily MLA2C4_14780 d7ad8ddf38ec726365cd38ba846fb07d 106 SUPERFAMILY SSF54292 11 90 2.08E-19 T 01-11-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MLA2C4_14780 d7ad8ddf38ec726365cd38ba846fb07d 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 2.3E-12 T 01-11-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MLA2C4_17690 9be1f6e36884fd9ee705f0b6c7fecfc8 261 Pfam PF13704 Glycosyl transferase family 2 18 104 6.9E-11 T 01-11-2018 MLA2C4_23970 93876dc32db410039051084d127d9aab 121 Pfam PF11518 Protein of unknown function (DUF3221) 14 119 6.5E-39 T 01-11-2018 IPR021598 Protein of unknown function DUF3221 MLA2C4_23970 93876dc32db410039051084d127d9aab 121 Gene3D G3DSA:2.40.50.140 36 119 3.1E-10 T 01-11-2018 MLA2C4_22165 07d85c8cffbb40c69e5ffe0d7a6c1c41 156 Pfam PF15980 Putative Competence protein ComGF 42 142 1.1E-19 T 01-11-2018 IPR016977 Competence operon G, ComGF MLA2C4_15970 af5901a613af9485c78d0f32602ba047 97 Pfam PF14118 YfzA-like protein 5 94 1.0E-44 T 01-11-2018 IPR025627 YfzA-like protein MLA2C4_14575 ffdf35f2c16e4b09e2d6f983dc3e8089 118 Gene3D G3DSA:3.30.1450.10 42 118 5.2E-5 T 01-11-2018 IPR037873 BamE-like MLA2C4_24655 49a1a87a31591a53ff41bab539b68c9e 407 Gene3D G3DSA:1.20.1530.20 2 384 2.6E-66 T 01-11-2018 IPR038770 Sodium/solute symporter superfamily MLA2C4_24655 49a1a87a31591a53ff41bab539b68c9e 407 Pfam PF00999 Sodium/hydrogen exchanger family 12 374 7.7E-60 T 01-11-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MLA2C4_16610 26835ab5729433616db3102caceab7c8 121 Pfam PF06486 Protein of unknown function (DUF1093) 34 105 1.3E-7 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_16610 26835ab5729433616db3102caceab7c8 121 SUPERFAMILY SSF159121 27 118 9.29E-18 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_16610 26835ab5729433616db3102caceab7c8 121 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 2 116 4.0E-8 T 01-11-2018 IPR006542 Protein of unknown function DUF1093 MLA2C4_16610 26835ab5729433616db3102caceab7c8 121 Gene3D G3DSA:2.40.50.480 27 117 1.5E-14 T 01-11-2018 IPR036166 YxeA-like superfamily MLA2C4_11250 e0f4ee89ea5319d23b41fef7d83a7509 195 SUPERFAMILY SSF52833 37 194 5.84E-40 T 01-11-2018 IPR036249 Thioredoxin-like superfamily MLA2C4_11250 e0f4ee89ea5319d23b41fef7d83a7509 195 Pfam PF02630 SCO1/SenC 25 176 5.2E-38 T 01-11-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MLA2C4_11250 e0f4ee89ea5319d23b41fef7d83a7509 195 Gene3D G3DSA:3.40.30.10 27 195 6.1E-57 T 01-11-2018 MLA2C4_08295 ba1d228c188208d1f79fb2ffab75e3ff 128 Pfam PF03994 Domain of Unknown Function (DUF350) 7 58 1.9E-11 T 01-11-2018 IPR007140 Protein of unknown function DUF350 MLA2C4_08295 ba1d228c188208d1f79fb2ffab75e3ff 128 Pfam PF03994 Domain of Unknown Function (DUF350) 72 126 2.5E-15 T 01-11-2018 IPR007140 Protein of unknown function DUF350 MLA2C4_14680 5c6212027d5da8fb40616465bd12394d 198 Gene3D G3DSA:2.60.20.10 107 198 4.3E-10 T 01-11-2018 MLA2C4_03005 c0eab79c1c578683c93ff3c2c5b8f7a1 434 Pfam PF03600 Citrate transporter 13 380 1.4E-51 T 01-11-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MLA2C4_03005 c0eab79c1c578683c93ff3c2c5b8f7a1 434 TIGRFAM TIGR00784 citMHS: citrate transporter 1 434 5.3E-206 T 01-11-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 MLA2C4_26555 bfccc3fabcdcbc0df0c0d3216baae652 122 Pfam PF03788 LrgA family 18 109 4.9E-23 T 01-11-2018 IPR005538 LrgA/CidA family GO:0016021 MLA2C4_21765 05f4e1f18a5d4bf45a45691d1b61f11d 333 Pfam PF00676 Dehydrogenase E1 component 24 323 4.0E-105 T 01-11-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MLA2C4_21765 05f4e1f18a5d4bf45a45691d1b61f11d 333 Gene3D G3DSA:3.40.50.970 2 333 1.8E-119 T 01-11-2018 MLA2C4_21765 05f4e1f18a5d4bf45a45691d1b61f11d 333 SUPERFAMILY SSF52518 10 333 5.4E-104 T 01-11-2018 IPR029061 Thiamin diphosphate-binding fold MLA2C4_01180 23bd5de3e9684c3476c02bfea300209f 46 Pfam PF14142 YrzO-like protein 1 46 6.9E-33 T 01-11-2018 IPR025417 YrzO-like protein MLA2C4_09035 140bc0be87fba98000ffa34022744fd0 226 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 223 4.8E-12 T 01-11-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MLA2C4_07775 7c7cdaa4d2ab9ecc154125006c30f6f3 385 Pfam PF01578 Cytochrome C assembly protein 77 382 1.5E-33 T 01-11-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MLA2C4_07775 7c7cdaa4d2ab9ecc154125006c30f6f3 385 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 42 385 3.6E-77 T 01-11-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 MLA2C4_20720 90e29db34ba1a39d6ccd9641f773202a 98 Pfam PF11256 Protein of unknown function (DUF3055) 5 84 2.5E-34 T 01-11-2018 IPR021415 Protein of unknown function DUF3055 MLA2C4_27870 1dbab5c4b26737f6606f336b46694847 230 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 79 8.1E-45 T 01-11-2018 IPR014243 Transcription factor, RsfA MLA2C4_27870 1dbab5c4b26737f6606f336b46694847 230 Pfam PF13921 Myb-like DNA-binding domain 8 57 3.1E-5 T 01-11-2018 MLA2C4_17820 ec3d898e42b44d5f9c7e457570ef83dd 177 Gene3D G3DSA:3.40.50.360 1 172 2.2E-52 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_17820 ec3d898e42b44d5f9c7e457570ef83dd 177 Pfam PF02525 Flavodoxin-like fold 1 167 4.5E-42 T 01-11-2018 IPR003680 Flavodoxin-like fold MLA2C4_17820 ec3d898e42b44d5f9c7e457570ef83dd 177 SUPERFAMILY SSF52218 1 171 1.24E-42 T 01-11-2018 IPR029039 Flavoprotein-like superfamily MLA2C4_05475 46521202f97e79c152e904883b17c314 66 Pfam PF14147 Sporulation protein YhaL 4 55 6.1E-29 T 01-11-2018 IPR025428 Sporulation protein YhaL MLA2C4_19300 ca0c66d50a55fbeeab6ba25974446a03 322 Pfam PF04230 Polysaccharide pyruvyl transferase 15 271 4.4E-21 T 01-11-2018 IPR007345 Polysaccharide pyruvyl transferase MLA2C4_16325 29a7869b7cb4d47458a3d369da4633b3 171 Gene3D G3DSA:1.20.1260.10 1 157 7.7E-62 T 01-11-2018 IPR012347 Ferritin-like MLA2C4_16325 29a7869b7cb4d47458a3d369da4633b3 171 Pfam PF11553 Protein of unknown function (DUF3231) 2 167 9.3E-46 T 01-11-2018 IPR021617 Protein of unknown function DUF3231 MLA2C4_06880 06aa7e1b0485e472283585aab2e29a17 201 Pfam PF07853 Protein of unknown function (DUF1648) 10 56 2.3E-13 T 01-11-2018 IPR012867 Domain of unknown function DUF1648 MLA2C4_14260 dc0f5e6c34b8e2cad2e0b61d0532b919 402 Pfam PF07690 Major Facilitator Superfamily 20 317 9.4E-25 T 01-11-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MLA2C4_14260 dc0f5e6c34b8e2cad2e0b61d0532b919 402 SUPERFAMILY SSF103473 7 393 6.28E-50 T 01-11-2018 IPR036259 MFS transporter superfamily MLA2C4_14260 dc0f5e6c34b8e2cad2e0b61d0532b919 402 Gene3D G3DSA:1.20.1250.20 1 396 4.8E-45 T 01-11-2018 MLA2C4_11690 1bdbe863f8601839c103363729f45007 315 Pfam PF10782 Zinc-finger 22 76 2.0E-7 T 01-11-2018 IPR019718 Protein of unknown function DUF2602 MLA2C4_26905 d460f3f75ca34e2f6d9540dd365f296e 357 ProSitePatterns PS01348 MraY family signature 2. 147 158 - T 01-11-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MLA2C4_26905 d460f3f75ca34e2f6d9540dd365f296e 357 Pfam PF00953 Glycosyl transferase family 4 72 231 9.3E-39 T 01-11-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MLA2C4_04425 1c8e514f58ed7744bbccbfbc46cd8b05 71 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 63 3.1E-9 T 01-11-2018 IPR020256 Spore coat protein CotJA MLA2C4_04425 1c8e514f58ed7744bbccbfbc46cd8b05 71 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 5 71 9.0E-33 T 01-11-2018 IPR020256 Spore coat protein CotJA MLA2C4_11305 ec4cb42bedd081a9eaba8ebd808b6132 182 Gene3D G3DSA:3.40.50.850 1 182 4.8E-53 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_11305 ec4cb42bedd081a9eaba8ebd808b6132 182 SUPERFAMILY SSF52499 2 176 2.62E-50 T 01-11-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MLA2C4_11305 ec4cb42bedd081a9eaba8ebd808b6132 182 Pfam PF00857 Isochorismatase family 4 176 6.9E-38 T 01-11-2018 IPR000868 Isochorismatase-like GO:0003824 MLA2C4_02470 d0abfbc757adc0c65576c15dc49b07c4 226 Pfam PF07947 YhhN family 49 222 5.7E-28 T 01-11-2018 IPR012506 YhhN-like GO:0016021 MLA2C4_08710 b509991706f4009f4d3cba1b91b77262 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 8.5E-13 T 01-11-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MLA2C4_08710 b509991706f4009f4d3cba1b91b77262 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 8.5E-13 T 01-11-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MLA2C4_08710 b509991706f4009f4d3cba1b91b77262 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 8.5E-13 T 01-11-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MLA2C4_08710 b509991706f4009f4d3cba1b91b77262 91 Pfam PF01313 Bacterial export proteins, family 3 6 76 1.9E-19 T 01-11-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MLA2C4_11875 d85ad834ffc34f563035b1615aa9faf7 380 Pfam PF04865 Baseplate J-like protein 66 312 9.4E-46 T 01-11-2018 IPR006949 Baseplate protein J-like MLA2C4_27995 25d9b48e30a753b349336655921b6b76 208 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 193 1.4E-8 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_02335 37c37cabcb3e44c07b5c414ac4ec8d8f 123 Pfam PF09350 Domain of unknown function (DUF1992) 7 73 8.2E-24 T 01-11-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain MLA2C4_18735 a0ba076d9770dae5bd0d92e734dd1e24 65 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 2 65 1.8E-28 T 01-11-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like MLA2C4_18735 a0ba076d9770dae5bd0d92e734dd1e24 65 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 65 25.881 T 01-11-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like MLA2C4_13390 4ce7dcab0ed31ef7a52241dd2ee2096c 214 Pfam PF13787 Protein of unknown function with HXXEE motif 43 154 7.4E-16 T 01-11-2018 IPR025671 Protein of unknown function with HXXEE motif MLA2C4_08890 75385e4a7b915a194dc3f6b1f5cf1209 213 Pfam PF13021 Domain of unknown function (DUF3885) 171 208 3.2E-20 T 01-11-2018 IPR024976 Domain of unknown function DUF3885 MLA2C4_15590 bb15988ab08a76ccd3918484114d2edd 101 Pfam PF14118 YfzA-like protein 7 97 3.4E-42 T 01-11-2018 IPR025627 YfzA-like protein MLA2C4_07860 ef4722cd7007c2a66ce754971589c265 78 Pfam PF13106 Domain of unknown function (DUF3961) 35 73 1.6E-30 T 01-11-2018 IPR025081 Domain of unknown function DUF3961 MLA2C4_18215 c63de2bdbbb8fe74af87cd41c0d77ac3 44 TIGRFAM TIGR04429 Phr_nterm: Phr family secreted Rap phosphatase inhibitor 1 26 2.2E-6 T 01-11-2018 IPR030968 Phr family, secreted RapG/RapK phosphatase inhibitor MLA2C4_01805 c49da6c87e919b513cb19ce57706920c 160 Pfam PF14275 Domain of unknown function (DUF4362) 48 143 1.2E-9 T 01-11-2018 IPR025372 Protein of unknown function DUF4362 MLA2C4_07530 8aee54ddcc1d89efd4735474a8f27bca 66 Pfam PF13046 Protein of unknown function (DUF3906) 1 64 1.6E-31 T 01-11-2018 IPR024998 Protein of unknown function DUF3906 MLA2C4_06715 c585a0e155395a121b1cfc6a8384e4e0 101 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 8 99 7.4E-23 T 01-11-2018 IPR009303 Protein of unknown function DUF960 MLA2C4_06715 c585a0e155395a121b1cfc6a8384e4e0 101 Gene3D G3DSA:3.10.450.150 1 101 1.4E-8 T 01-11-2018 MLA2C4_09010 70e0a430fe07ec4aeb7d365dc2a496d1 131 Pfam PF13078 Protein of unknown function (DUF3942) 5 129 3.6E-60 T 01-11-2018 IPR025074 Protein of unknown function DUF3942 MLA2C4_25005 daa21a5d5e7489ebadf14aa5c51aeca6 168 Pfam PF13785 Domain of unknown function (DUF4178) 28 158 6.3E-26 T 01-11-2018 IPR025235 Domain of unknown function DUF4178 MLA2C4_04695 be98dc9c4efaa60a7183309d4861a973 378 Pfam PF04286 Protein of unknown function (DUF445) 14 376 4.7E-85 T 01-11-2018 IPR007383 Protein of unknown function DUF445 MLA2C4_04695 be98dc9c4efaa60a7183309d4861a973 378 PIRSF PIRSF032178 1 378 1.2E-139 T 01-11-2018 IPR016991 Protein of unknown function UCP032178 MLA2C4_05065 1ed5e0961a57f0c612a7ae9b2f49228e 85 Pfam PF13780 Domain of unknown function (DUF4176) 7 79 2.8E-29 T 01-11-2018 IPR025233 Protein of unknown function DUF4176 MLA2C4_10155 2f39c201763d06abdfef551dca97b039 65 Pfam PF13314 Domain of unknown function (DUF4083) 7 63 3.1E-24 T 01-11-2018 IPR025143 Protein of unknown function DUF4083 MLA2C4_07505 0d820d6304b76efb8581b91c2854e097 47 Pfam PF10055 Uncharacterized small protein (DUF2292) 10 46 5.1E-19 T 01-11-2018 IPR018743 Protein of unknown function DUF2292 MLA2C4_09825 560d9f88d5ff8805c23485335cd4ac07 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 5.0E-38 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_09680 9e9b2cb9dddaea23a36e2f581a5a525e 415 Pfam PF13687 Domain of unknown function (DUF4153) 209 378 7.1E-8 T 01-11-2018 IPR025291 Protein of unknown function DUF4153 MLA2C4_05670 fb59fce88993c6de084bfc9221daaae3 88 Pfam PF14206 Cysteine-rich CPCC 3 77 4.3E-34 T 01-11-2018 IPR025983 Cysteine-rich CPCC domain MLA2C4_02590 68e88838fa8b33e5ac6f4e3a8f43d02b 113 Pfam PF13108 Protein of unknown function (DUF3969) 9 111 8.0E-36 T 01-11-2018 IPR025083 Protein of unknown function DUF3969 MLA2C4_20255 6e4ade058fa5da13001aa99a8929f172 387 Pfam PF07007 Lysozyme inhibitor LprI 301 381 9.2E-12 T 01-11-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal MLA2C4_26270 978c6958125bef9fe49de349ea98ae8a 197 Pfam PF09335 SNARE associated Golgi protein 30 155 8.9E-25 T 01-11-2018 IPR032816 SNARE associated Golgi protein MLA2C4_12735 e9ac99adec43eb069996a478493ee74e 277 Pfam PF13120 Domain of unknown function (DUF3974) 1 126 1.6E-84 T 01-11-2018 IPR025005 Domain of unknown function DUF3974 MLA2C4_08020 0ba3d4ad89859a54007ec92a6f954a53 196 Pfam PF07187 Protein of unknown function (DUF1405) 24 180 1.1E-57 T 01-11-2018 IPR009845 Protein of unknown function DUF1405 MLA2C4_06020 a4b745a323614c3cc8f78feca5644a6d 204 Pfam PF10737 Spore germination protein GerPC 23 198 1.0E-60 T 01-11-2018 IPR019673 Spore germination protein GerPC MLA2C4_12465 302164629d8cfb9a46a62de984d867bd 295 Pfam PF02517 CAAX protease self-immunity 138 225 7.9E-9 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_28060 af7c50c2f7d0e66fbda41ebdb59a40c0 67 Pfam PF04328 Selenoprotein, putative 4 67 2.6E-24 T 01-11-2018 IPR007423 Selenoprotein, putative MLA2C4_20635 7e64914ab4d4b340309eaa83cc51a49d 165 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 164 7.0E-87 T 01-11-2018 IPR020229 Uncharacterised protein YlaL MLA2C4_25625 e4310f1ee15fb341b88e4502a16eeb34 105 Pfam PF14068 Putative membrane protein 6 105 2.1E-41 T 01-11-2018 IPR025917 Putative membrane protein YuiB MLA2C4_21905 1795677ed7c9515bcb12c6ea18693b89 220 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 33 220 2.2E-72 T 01-11-2018 IPR014195 Sporulation stage III, protein AG MLA2C4_12085 f26ac21907c808003f0d4687f3787d4c 69 Pfam PF13619 KTSC domain 8 64 1.1E-17 T 01-11-2018 IPR025309 KTSC domain MLA2C4_22160 3ad9d730e7d65fb9a53081d2e476ed29 123 Pfam PF14173 ComG operon protein 7 32 122 6.9E-23 T 01-11-2018 IPR020372 Competence operon G protein 7, ComGG MLA2C4_21495 fe9380835823f45ac9618e404cb80343 81 Pfam PF10827 Protein of unknown function (DUF2552) 1 79 7.8E-45 T 01-11-2018 IPR020157 Uncharacterised protein family YqkC MLA2C4_21495 fe9380835823f45ac9618e404cb80343 81 ProDom PD058987 CYTOSOLIC YQKC 21 81 7.0E-30 T 01-11-2018 IPR020157 Uncharacterised protein family YqkC MLA2C4_26100 68b9bba78748ced79bac1feefa4dfa94 235 Pfam PF10612 Spore coat protein Z 16 116 2.1E-7 T 01-11-2018 IPR019593 Spore coat protein Z/Y MLA2C4_10255 dd77202bb00bdd93af45238545753055 151 Pfam PF13075 Protein of unknown function (DUF3939) 10 140 2.0E-45 T 01-11-2018 IPR025071 Protein of unknown function DUF3939 MLA2C4_22080 ef038b94c8aa222fba178aa10c06fbc7 222 Pfam PF13346 ABC-2 family transporter protein 3 218 1.7E-25 T 01-11-2018 IPR025699 ABC-2 membrane transporter-like MLA2C4_24345 83316ede8ceeb398756ae344b6842754 134 Pfam PF06713 Bacterial PH domain 63 123 1.0E-8 T 01-11-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 MLA2C4_13240 bfa7c9f3e049f4ac0e92dac8061768c2 779 Pfam PF02687 FtsX-like permease family 678 768 5.2E-11 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_13240 bfa7c9f3e049f4ac0e92dac8061768c2 779 Pfam PF02687 FtsX-like permease family 287 378 4.7E-10 T 01-11-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MLA2C4_18595 a0462cc034b6f5e09577b9ead13a5a0f 380 SUPERFAMILY SSF69572 84 357 2.88E-50 T 01-11-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MLA2C4_18595 a0462cc034b6f5e09577b9ead13a5a0f 380 Gene3D G3DSA:3.40.50.720 95 358 6.4E-60 T 01-11-2018 MLA2C4_18595 a0462cc034b6f5e09577b9ead13a5a0f 380 Pfam PF00899 ThiF family 113 324 9.2E-40 T 01-11-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MLA2C4_19130 00aa86647b60e88dfc266995bc41ab28 339 Pfam PF08378 Nuclease-related domain 150 279 2.1E-8 T 01-11-2018 IPR011528 Nuclease-related domain, NERD MLA2C4_02430 fb961b57893091132ccdd61efdb83a8c 360 PIRSF PIRSF026508 1 360 1.2E-125 T 01-11-2018 IPR008863 Toxic anion resistance MLA2C4_02430 fb961b57893091132ccdd61efdb83a8c 360 Pfam PF05816 Toxic anion resistance protein (TelA) 31 359 2.0E-102 T 01-11-2018 IPR008863 Toxic anion resistance MLA2C4_13215 a80365d29ac6141849b7df25f30467c1 426 Pfam PF01391 Collagen triple helix repeat (20 copies) 226 283 7.6E-8 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_04255 3e445553c85a5165942a01daa466b64f 194 Pfam PF11579 Protein of unknown function (DUF3238) 1 192 2.1E-110 T 01-11-2018 IPR021631 Protein of unknown function DUF3238 MLA2C4_26170 f795af11cc007c7837afc79e5c759ddf 46 Pfam PF13153 Protein of unknown function (DUF3985) 1 44 2.8E-26 T 01-11-2018 IPR025053 Protein of unknown function DUF3985 MLA2C4_13170 cdab53d27e688b80548f6ec92c3160b6 206 Pfam PF13814 Replication-relaxation 16 173 2.5E-22 T 01-11-2018 IPR025855 Plasmid replication-relaxation MLA2C4_06645 9614c1de3073d6cab5774d223a8537b2 82 Pfam PF13780 Domain of unknown function (DUF4176) 3 73 7.9E-23 T 01-11-2018 IPR025233 Protein of unknown function DUF4176 MLA2C4_01820 15ee6cc019708db110bcc23977abacd9 125 Pfam PF11127 Protein of unknown function (DUF2892) 1 62 2.5E-11 T 01-11-2018 IPR021309 Protein of unknown function DUF2892 MLA2C4_01985 a98173f02ef0dbb3648d54ecc110b389 172 Pfam PF07308 Protein of unknown function (DUF1456) 105 172 2.0E-21 T 01-11-2018 IPR009921 Domain of unknown function DUF1456 MLA2C4_01985 a98173f02ef0dbb3648d54ecc110b389 172 Pfam PF07308 Protein of unknown function (DUF1456) 5 86 1.7E-25 T 01-11-2018 IPR009921 Domain of unknown function DUF1456 MLA2C4_14250 3a705678819c5a78013ca1dd56936256 87 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 1 85 2.1E-33 T 01-11-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family MLA2C4_18540 a1c69675682d3171ef27fd89ca361c68 160 Pfam PF07849 Protein of unknown function (DUF1641) 118 155 5.1E-18 T 01-11-2018 IPR012440 Protein of unknown function DUF1641 MLA2C4_07605 99f057991df008a5a96c0de67534f750 112 Pfam PF13059 Protein of unknown function (DUF3992) 32 110 5.6E-54 T 01-11-2018 IPR025035 Protein of unknown function DUF3922 MLA2C4_14960 5ea68ce27e364a594a0cac0c7355f87d 98 Gene3D G3DSA:1.10.40.50 15 87 1.6E-16 T 01-11-2018 MLA2C4_21405 99b88f04b0705f31a5d0e1efc057a4c0 76 Pfam PF14004 Protein of unknown function (DUF4227) 6 76 4.3E-29 T 01-11-2018 IPR025321 Protein of unknown function DUF4227 MLA2C4_18230 1fa1fd04f4c38d25c6fd7598d0af8902 115 Pfam PF14079 Domain of unknown function (DUF4260) 3 114 3.4E-43 T 01-11-2018 IPR025356 Protein of unknown function DUF4260 MLA2C4_07955 0de6ffe5442a45bedfe52099b40ff112 249 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 230 4.2E-78 T 01-11-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 MLA2C4_00540 92bc0f22f25f0e8b31c54cf1d92b2b74 369 SMART SM00670 169 276 2.6E-13 T 01-11-2018 IPR002716 PIN domain MLA2C4_00540 92bc0f22f25f0e8b31c54cf1d92b2b74 369 SUPERFAMILY SSF88723 169 297 3.64E-25 T 01-11-2018 IPR029060 PIN-like domain superfamily MLA2C4_00540 92bc0f22f25f0e8b31c54cf1d92b2b74 369 Gene3D G3DSA:3.40.50.1010 165 300 8.2E-54 T 01-11-2018 MLA2C4_11780 c0f0fcdb5de34e3ca8b6620f87d22603 538 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 51 509 5.1E-64 T 01-11-2018 IPR021145 Portal protein MLA2C4_11990 89fde7ecb56b3df328d6e413c4ac86ed 132 SMART SM00754 1 131 6.1E-36 T 01-11-2018 IPR010895 CHRD MLA2C4_11990 89fde7ecb56b3df328d6e413c4ac86ed 132 Pfam PF07452 CHRD domain 2 129 5.4E-27 T 01-11-2018 IPR010895 CHRD MLA2C4_27265 dc892ea9565a684b89093da05b631c04 405 Pfam PF04230 Polysaccharide pyruvyl transferase 16 340 1.7E-35 T 01-11-2018 IPR007345 Polysaccharide pyruvyl transferase MLA2C4_19195 e46fa89eb20c708b4cd4da0843b3efe2 79 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 2.9E-28 T 01-11-2018 IPR009242 Protein of unknown function DUF896 MLA2C4_19195 e46fa89eb20c708b4cd4da0843b3efe2 79 Gene3D G3DSA:1.10.287.540 2 58 8.6E-21 T 01-11-2018 MLA2C4_19195 e46fa89eb20c708b4cd4da0843b3efe2 79 SUPERFAMILY SSF158221 1 42 1.31E-13 T 01-11-2018 MLA2C4_19195 e46fa89eb20c708b4cd4da0843b3efe2 79 Hamap MF_01103 UPF0291 protein . 2 60 16.314 T 01-11-2018 IPR009242 Protein of unknown function DUF896 MLA2C4_01870 2fbbf1d492095bda6e6d39b489d8fd71 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 8.1E-16 T 01-11-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MLA2C4_01870 2fbbf1d492095bda6e6d39b489d8fd71 221 Gene3D G3DSA:1.10.3720.10 9 216 2.1E-42 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_01870 2fbbf1d492095bda6e6d39b489d8fd71 221 SUPERFAMILY SSF161098 9 205 9.29E-41 T 01-11-2018 IPR035906 MetI-like superfamily MLA2C4_04800 acc8318fd595abdd540f4e4234493121 874 Pfam PF00395 S-layer homology domain 155 196 6.5E-4 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04800 acc8318fd595abdd540f4e4234493121 874 Pfam PF00395 S-layer homology domain 33 75 1.5E-10 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04800 acc8318fd595abdd540f4e4234493121 874 Pfam PF00395 S-layer homology domain 93 135 2.8E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_04800 acc8318fd595abdd540f4e4234493121 874 Gene3D G3DSA:2.60.40.1080 426 505 2.4E-6 T 01-11-2018 MLA2C4_14720 b1e55351d2f0ac3c5a05378655fd56ab 126 Pfam PF13789 Domain of unknown function (DUF4181) 18 118 3.9E-30 T 01-11-2018 IPR025441 Protein of unknown function DUF4181 MLA2C4_27445 e4c4b0e51fa38c3458ae5c064ea5f7ac 206 Pfam PF06161 Protein of unknown function (DUF975) 119 205 6.3E-27 T 01-11-2018 IPR010380 Protein of unknown function DUF975 MLA2C4_27445 e4c4b0e51fa38c3458ae5c064ea5f7ac 206 Pfam PF06161 Protein of unknown function (DUF975) 2 126 3.6E-14 T 01-11-2018 IPR010380 Protein of unknown function DUF975 MLA2C4_25025 9c74cf1551819cd290900c99c3e690e3 55 Pfam PF12669 Virus attachment protein p12 family 4 46 2.2E-10 T 01-11-2018 MLA2C4_17210 c1f422b40ada0b38e24e4486f51b391c 366 Pfam PF00395 S-layer homology domain 115 156 1.9E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17210 c1f422b40ada0b38e24e4486f51b391c 366 Pfam PF00395 S-layer homology domain 54 96 7.4E-11 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17210 c1f422b40ada0b38e24e4486f51b391c 366 Pfam PF00395 S-layer homology domain 172 215 1.2E-7 T 01-11-2018 IPR001119 S-layer homology domain MLA2C4_17075 42b0cd89fc33efc377e896ed273bd2e4 89 Pfam PF13239 2TM domain 9 86 1.0E-29 T 01-11-2018 IPR025698 2TM domain MLA2C4_01900 c2fb865f2ec66244c2658cb8337dc1bb 78 Pfam PF05360 yiaA/B two helix domain 9 61 1.9E-18 T 01-11-2018 IPR008024 YiaAB two helix MLA2C4_19555 ab81916668cf95c08174cb6f95718248 212 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 39 197 3.5E-6 T 01-11-2018 IPR003740 Uncharacterised membrane protein YitT MLA2C4_21010 e70139002c0720e2aa616476d86e3fe2 151 Pfam PF06271 RDD family 9 144 4.5E-25 T 01-11-2018 IPR010432 RDD MLA2C4_15250 173ee5ef25670de8da23e1a608242681 236 Pfam PF04519 Polymer-forming cytoskeletal 58 119 3.7E-8 T 01-11-2018 IPR007607 Bactofilin A/B MLA2C4_15250 173ee5ef25670de8da23e1a608242681 236 Pfam PF04519 Polymer-forming cytoskeletal 20 81 2.6E-8 T 01-11-2018 IPR007607 Bactofilin A/B MLA2C4_16630 efc276ed13f986cf9f88f464b1970a0c 188 Pfam PF12952 Domain of unknown function (DUF3841) 19 89 1.6E-8 T 01-11-2018 IPR024211 Protein of unknown function DUF3841 MLA2C4_20280 36a7b6f67eab6d5b293a924ee361e01e 121 Pfam PF14037 YoqO-like protein 3 117 1.7E-41 T 01-11-2018 IPR025621 YoqO-like protein MLA2C4_13745 c28dfdcd9f4f85abbb2cad334c2df38a 115 SUPERFAMILY SSF49464 39 101 5.49E-7 T 01-11-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily MLA2C4_06665 c5727f42083900db68587513f48c4445 679 Pfam PF04411 PD-(D/E)XK nuclease superfamily 377 480 2.2E-6 T 01-11-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 MLA2C4_22005 65d4e3957be6ed95fb4e9dbb3ce098d7 228 Pfam PF06570 Protein of unknown function (DUF1129) 36 222 3.4E-8 T 01-11-2018 IPR009214 Protein of unknown function DUF1129 MLA2C4_22005 65d4e3957be6ed95fb4e9dbb3ce098d7 228 SUPERFAMILY SSF158560 2 98 9.03E-27 T 01-11-2018 MLA2C4_10425 d85420bad0a21a9870ac270ce4a56f71 160 Pfam PF04306 Protein of unknown function (DUF456) 21 156 5.6E-37 T 01-11-2018 IPR007403 Protein of unknown function DUF456 MLA2C4_23080 9ea196f0b5a7e30ff1cc940c4aab0e31 215 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 206 2.3E-39 T 01-11-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like MLA2C4_07215 e1be166095cc7106c0862ab15dceb30f 60 Pfam PF13052 Protein of unknown function (DUF3913) 2 58 4.0E-44 T 01-11-2018 IPR025024 Protein of unknown function DUF3913 MLA2C4_17705 d2187a5d63972912a8bb7e34418ff227 57 Pfam PF06906 Protein of unknown function (DUF1272) 2 56 1.2E-25 T 01-11-2018 IPR010696 Protein of unknown function DUF1272 MLA2C4_27550 1f920894316e5ad7e1c48d2b93cd834f 171 Gene3D G3DSA:1.20.1260.50 2 164 4.4E-7 T 01-11-2018 MLA2C4_08205 4c4020413b40c6863f1a03cd571b737d 60 Pfam PF13060 Protein of unknown function (DUF3921) 1 58 3.6E-42 T 01-11-2018 IPR025036 Protein of unknown function DUF3921 MLA2C4_07375 c8d52caf6293795860a7be65c13426a3 79 Pfam PF13050 Protein of unknown function (DUF3911) 1 77 3.5E-56 T 01-11-2018 IPR025022 Protein of unknown function DUF3911 MLA2C4_08390 978d4e23a8144881844b2b0bb4a1569b 209 Pfam PF04116 Fatty acid hydroxylase superfamily 42 183 3.4E-18 T 01-11-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MLA2C4_07280 ee41c2ffbdbbd18fce48911b8f31f43d 48 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 6 48 3.5E-20 T 01-11-2018 IPR021008 Protein of unknown function DUF3687 MLA2C4_05290 84689669552d3a6b47db8eb2bc3cfcea 129 Pfam PF11181 Heat induced stress protein YflT 12 109 3.0E-31 T 01-11-2018 IPR025889 General stress protein 17M-like domain MLA2C4_15975 e57143e7f3acaff152403c4a8c495a95 205 Pfam PF13346 ABC-2 family transporter protein 3 201 1.8E-32 T 01-11-2018 IPR025699 ABC-2 membrane transporter-like MLA2C4_21925 0faccc829ae27dccef93d93c60c4d23a 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 1.8E-29 T 01-11-2018 IPR009570 Stage III sporulation protein AC MLA2C4_21925 0faccc829ae27dccef93d93c60c4d23a 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 2.0E-14 T 01-11-2018 IPR025664 Stage III sporulation protein AC/AD family MLA2C4_17225 5f083298f50431b4b62d61d06983151a 66 Pfam PF14044 NETI protein 9 64 2.5E-31 T 01-11-2018 IPR025930 NETI protein MLA2C4_16265 5876a2e4e06371439106d18e76acda70 442 Pfam PF07670 Nucleoside recognition 136 229 5.0E-8 T 01-11-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MLA2C4_01275 dfe838289851fdda8c4142a6116ba7f7 398 Pfam PF12698 ABC-2 family transporter protein 21 392 2.2E-37 T 01-11-2018 MLA2C4_05885 852ab00977fb8ff94a38d47fec8e1c1b 284 Pfam PF02517 CAAX protease self-immunity 129 211 7.7E-16 T 01-11-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MLA2C4_17120 8bd39fbaa8103b2c1a709119338708a4 63 Pfam PF04070 Domain of unknown function (DUF378) 2 56 2.7E-16 T 01-11-2018 IPR007211 Protein of unknown function DUF378 MLA2C4_03720 ce1596486543a3cf1d1d2485704531f5 65 Pfam PF11755 Protein of unknown function (DUF3311) 7 60 1.7E-15 T 01-11-2018 IPR021741 Protein of unknown function DUF3311 MLA2C4_02765 9ddf30db7fcb1958056cba3b9ac78d54 263 Pfam PF06182 ABC-2 family transporter protein 31 258 7.2E-22 T 01-11-2018 IPR010390 Protein of unknown function DUF990 MLA2C4_24430 dc71cbc47f34a9e855a21698ed33c198 103 Pfam PF03413 Peptidase propeptide and YPEB domain 30 100 3.5E-9 T 01-11-2018 IPR025711 PepSY domain MLA2C4_13675 990fe43dcf41d90830eb009ca5b4bd1f 186 Gene3D G3DSA:3.90.79.10 9 145 1.7E-10 T 01-11-2018 MLA2C4_13675 990fe43dcf41d90830eb009ca5b4bd1f 186 SUPERFAMILY SSF55811 35 114 4.2E-9 T 01-11-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MLA2C4_10745 39e2749046a5119be50d056eb9c863f7 212 Pfam PF00882 Zinc dependent phospholipase C 6 88 1.7E-6 T 01-11-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 MLA2C4_21135 9ba739a60865ecf0e2d6c354c60aa801 110 Pfam PF13077 Protein of unknown function (DUF3909) 1 108 7.5E-72 T 01-11-2018 IPR025073 Protein of unknown function DUF3909 MLA2C4_24765 22c196c72b6460b11848cd016d5513bb 354 Pfam PF10776 Protein of unknown function (DUF2600) 20 349 2.7E-153 T 01-11-2018 IPR019712 Protein of unknown function DUF2600 MLA2C4_17590 7d8a15750ceb1f770a54f6155c8def63 373 Pfam PF01594 AI-2E family transporter 34 364 1.3E-78 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like MLA2C4_09765 c4c68fcb253ad91e29cdea50dc053308 337 Pfam PF01594 AI-2E family transporter 16 328 1.6E-45 T 01-11-2018 IPR002549 Transmembrane protein TqsA-like MLA2C4_19070 d911cb793eda0922e100b5819f21a0bf 314 Pfam PF12679 ABC-2 family transporter protein 3 313 6.3E-14 T 01-11-2018 IPR032688 ABC-2 family transporter protein GO:0055085 MLA2C4_19385 ff45a400fbb4272facb6d0f85eca01f6 1205 Pfam PF01391 Collagen triple helix repeat (20 copies) 158 212 8.5E-8 T 01-11-2018 IPR008160 Collagen triple helix repeat MLA2C4_19815 b1c45f2fcd0db5bdf11204e456749945 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 288 1.6E-40 T 01-11-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MLA2C4_05490 f819372542f1d0b1ba5bf249eb132669 357 Pfam PF13159 Domain of unknown function (DUF3994) 161 289 4.3E-29 T 01-11-2018 IPR025057 Domain of unknown function DUF3994 MLA2C4_13015 1bc1383306383930be9de54056e21e48 74 Pfam PF11133 Head fiber protein 39 72 5.7E-8 T 01-11-2018 IPR022741 Bacteriophage B103, Gp8, head fibre MLA2C4_16165 ddf40b75e84d35df19128e07977634db 320 Pfam PF06166 Protein of unknown function (DUF979) 8 318 6.3E-124 T 01-11-2018 IPR009323 Protein of unknown function DUF979 MLA2C4_08750 4f935cf728515cf5eef24062630c5fcd 241 Pfam PF03591 AzlC protein 25 165 2.0E-40 T 01-11-2018 IPR011606 Branched-chain amino acid transport, permease MLA2C4_26710 71d256705e69f439df2fb5b95f88df0e 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 111 3.8E-25 T 01-11-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV MLA2C4_08605 c73ae3e50bfea740f627e0bdfa0281d7 99 Pfam PF02049 Flagellar hook-basal body complex protein FliE 33 99 4.2E-13 T 01-11-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MLA2C4_22455 ae2674e8d62015dcc024d7c592020cee 47 Pfam PF14006 YqzL-like protein 3 46 3.2E-20 T 01-11-2018 IPR025617 YqzL-like protein MLA2C4_24975 31cb9ab6e3239a283b87702d42797cd1 77 Pfam PF10676 Spore germination protein gerPA/gerPF 7 75 3.4E-20 T 01-11-2018 IPR019618 Spore germination protein GerPA/GerPF MLA2C4_07610 8444c1cb72938d378749843382292153 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 419 2.2E-142 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_07610 8444c1cb72938d378749843382292153 451 Pfam PF05525 Branched-chain amino acid transport protein 6 432 3.8E-158 T 01-11-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MLA2C4_11835 c132ef3e39ca7ddca2459d35636a681d 463 Gene3D G3DSA:3.30.160.610 90 187 4.4E-8 T 01-11-2018 MLA2C4_10855 cfea45449153c58108d52bb0319cd66c 165 Pfam PF06114 IrrE N-terminal-like domain 37 148 1.9E-11 T 01-11-2018 IPR010359 IrrE N-terminal-like domain MLA2C4_02260 8a67205936e421991ec016eaa596b5cf 412 Pfam PF12698 ABC-2 family transporter protein 19 385 3.1E-51 T 01-11-2018 MLA2C4_16025 727fc7237fb430d9ecb9250f19cea7f8 133 Pfam PF13140 Domain of unknown function (DUF3980) 47 131 3.9E-35 T 01-11-2018 IPR025044 Domain of unknown function DUF3980 MLA2C4_01845 41730e6292e8b1b20e2dc8327dd3105d 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 245 8.1E-44 T 01-11-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MLA2C4_05465 a0d1d63a0d5b6edeae841cb1897fc641 69 TIGRFAM TIGR04429 Phr_nterm: Phr family secreted Rap phosphatase inhibitor 1 27 5.3E-8 T 01-11-2018 IPR030968 Phr family, secreted RapG/RapK phosphatase inhibitor MLA2C4_27505 7ed09f5a23a1305a6d06500dd4f9a693 37 Pfam PF13216 Protein of unknown function (DUF4024) 1 35 1.7E-29 T 01-11-2018 IPR025099 Protein of unknown function DUF4024 MLA2C4_20715 4d829e4648a34cf3b200af2b6ab7aa08 42 Pfam PF13790 SR1 protein 1 37 3.1E-19 T 01-11-2018 IPR025236 SR1 protein MLA2C4_24725 9a92523579e516fcd0427c71c66d81ab 168 Gene3D G3DSA:2.60.40.1240 41 168 4.2E-5 T 01-11-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily MLA2C4_11955 b59f6db48ac4574fbe321952c3384ecf 206 Pfam PF13814 Replication-relaxation 16 174 2.7E-18 T 01-11-2018 IPR025855 Plasmid replication-relaxation MLA2C4_12560 09401bd94a0d51e8749ab13b7523bcae 194 Pfam PF01810 LysE type translocator 13 193 3.2E-17 T 01-11-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MLA2C4_22075 8e4a54f995d7b2e166b7682fda194b6d 210 Pfam PF13346 ABC-2 family transporter protein 3 206 4.6E-34 T 01-11-2018 IPR025699 ABC-2 membrane transporter-like MLA2C4_12695 57719f4f932ab696e00acc34bfbf438e 96 Pfam PF13799 Domain of unknown function (DUF4183) 23 93 3.1E-17 T 01-11-2018 IPR025237 Domain of unknown function DUF4183 MLA2C4_26965 f983c654a1d97f6b108b6309f82914f3 39 Pfam PF11457 Protein of unknown function (DUF3021) 11 38 1.0E-5 T 01-11-2018 IPR021560 Protein of unknown function DUF3021