locus-tag	class	description
I9X38_00015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
I9X38_00020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I9X38_00025	COG1396	sequence-specific DNA binding
I9X38_00030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I9X38_00035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I9X38_00040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I9X38_00045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I9X38_00050	COG0512	Glutamine amidotransferase of anthranilate synthase
I9X38_00055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I9X38_00060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I9X38_00065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I9X38_00070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
I9X38_00075	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
I9X38_00080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I9X38_00085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I9X38_00090	COG0037	tRNA processing
I9X38_00095	COG0515	serine threonine protein kinase
I9X38_00100	COG2304	oxidoreductase activity
I9X38_00105	COG2208	phosphoserine phosphatase activity
I9X38_00120	COG1098	S1 RNA binding domain
I9X38_00125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
I9X38_00140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I9X38_00145	COG3956	TIGRFAM MazG family protein
I9X38_00150	COG2244	polysaccharide biosynthetic process
I9X38_00155	COG2002	toxin-antitoxin pair type II binding
I9X38_00160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I9X38_00170	COG0193	aminoacyl-tRNA hydrolase activity
I9X38_00175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
I9X38_00180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
I9X38_00185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
I9X38_00190	COG2088	sporulation resulting in formation of a cellular spore
I9X38_00195	COG0251	oxidation-reduction process
I9X38_00200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I9X38_00205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
I9X38_00215	COG4466	Protein conserved in bacteria
I9X38_00225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
I9X38_00230	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
I9X38_00235	COG3584	3D domain protein
I9X38_00235	COG3583	domain protein
I9X38_00240	COG0084	hydrolase, TatD family'
I9X38_00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I9X38_00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I9X38_00250	COG2002	toxin-antitoxin pair type II binding
I9X38_00255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I9X38_00260	COG2827	Endonuclease containing a URI domain
I9X38_00265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
I9X38_00275	COG1774	PSP1 C-terminal conserved region
I9X38_00280	COG0470	DNA polymerase III
I9X38_00285	COG1728	Protein conserved in bacteria
I9X38_00290	COG3870	Protein conserved in bacteria
I9X38_00295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
I9X38_00300	COG1982	Orn Lys Arg decarboxylase major
I9X38_00305	COG3853	Toxic anion resistance protein (TelA)
I9X38_00310	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
I9X38_00325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_00335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_00335	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_00335	COG3321	synthase
I9X38_00335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_00335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_00345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_00380	COG3443	Belongs to the bacterial solute-binding protein 9 family
I9X38_00390	COG2851	Citrate transporter
I9X38_00395	COG0583	DNA-binding transcription factor activity
I9X38_00400	COG2828	Protein conserved in bacteria
I9X38_00425	COG2721	sulfolactate sulfo-lyase activity
I9X38_00470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I9X38_00470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I9X38_00525	COG1994	Peptidase M50
I9X38_00530	COG1942	4-Oxalocrotonate Tautomerase
I9X38_00535	COG1846	Transcriptional regulator
I9X38_00540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I9X38_00545	COG0004	ammonium transporteR
I9X38_00555	COG0477	Major facilitator Superfamily
I9X38_00560	COG1959	2 iron, 2 sulfur cluster binding
I9X38_00565	COG3465	dGTPase activity
I9X38_00570	COG1078	dGTPase activity
I9X38_00575	COG4844	belongs to the
I9X38_00585	COG0697	spore germination
I9X38_00590	COG0095	Lipoate-protein ligase
I9X38_00595	COG0583	DNA-binding transcription factor activity
I9X38_00600	COG0280	phosphate acetyltransferase
I9X38_00605	COG3253	May function as heme-dependent peroxidase
I9X38_00610	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_00615	COG0436	Aminotransferase
I9X38_00620	COG2814	Major facilitator Superfamily
I9X38_00625	COG0151	Belongs to the GarS family
I9X38_00630	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_00635	COG1917	Cupin 2, conserved barrel domain protein
I9X38_00640	COG0077	Prephenate dehydratase
I9X38_00645	COG2814	Major facilitator Superfamily
I9X38_00655	COG0833	amino acid
I9X38_00660	COG4187	Peptidase family M20/M25/M40
I9X38_00665	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_00670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I9X38_00680	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
I9X38_00685	COG1091	dTDP-4-dehydrorhamnose reductase activity
I9X38_00690	COG1088	dTDP-glucose 4,6-dehydratase activity
I9X38_00695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I9X38_00700	COG3980	spore coat polysaccharide biosynthesis protein
I9X38_00705	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
I9X38_00710	COG2089	acid synthase
I9X38_00715	COG0456	acetyltransferase
I9X38_00720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I9X38_00725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I9X38_00730	COG0463	Glycosyl transferase, family 2
I9X38_00740	COG2363	Small membrane protein
I9X38_00745	COG2233	PERMEase
I9X38_00755	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_00760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
I9X38_00765	COG1216	Glycosyl transferase, family 2
I9X38_00780	COG1695	Transcriptional regulator
I9X38_00785	COG0351	phosphomethylpyrimidine kinase
I9X38_00795	COG1621	beta-fructofuranosidase activity
I9X38_00800	COG1263	PTS System
I9X38_00800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_00805	COG2116	formate transmembrane transporter activity
I9X38_00810	COG3711	transcriptional antiterminator
I9X38_00820	COG1404	Belongs to the peptidase S8 family
I9X38_00825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I9X38_00830	COG0778	Nitroreductase
I9X38_00835	COG0772	Belongs to the SEDS family
I9X38_00860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I9X38_00865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I9X38_00870	COG2261	transglycosylase associated protein
I9X38_00875	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
I9X38_00880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
I9X38_00885	COG2246	polysaccharide biosynthetic process
I9X38_00890	COG1309	transcriptional regulator
I9X38_00900	COG3162	membrane
I9X38_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I9X38_00910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I9X38_00915	COG2837	iron assimilation
I9X38_00920	COG2822	iron ion transport
I9X38_00925	COG0672	)-iron permease
I9X38_00930	COG0352	thiamine-phosphate diphosphorylase activity
I9X38_00935	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
I9X38_00940	COG0583	DNA-binding transcription factor activity
I9X38_00945	COG1380	Effector of murein hydrolase LrgA
I9X38_00950	COG1346	cytolysis
I9X38_00960	COG4895	conserved protein (DUF2196)
I9X38_00965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
I9X38_00970	COG0346	lactoylglutathione lyase activity
I9X38_00980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I9X38_00985	COG1404	Belongs to the peptidase S8 family
I9X38_00990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_00990	COG1263	PTS System
I9X38_00995	COG3711	transcriptional antiterminator
I9X38_01000	COG1442	glycosyl transferase family 8
I9X38_01005	COG5522	Integral membrane protein (intg_mem_TP0381)
I9X38_01010	COG1846	Transcriptional regulator
I9X38_01015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
I9X38_01020	COG2234	aminopeptidase activity
I9X38_01025	COG2357	RelA SpoT domain protein
I9X38_01030	COG1575	Belongs to the MenA family. Type 1 subfamily
I9X38_01040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_01045	COG1696	Membrane protein involved in D-alanine export
I9X38_01050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_01055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
I9X38_01060	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
I9X38_01065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I9X38_01070	COG1486	melibiose metabolic process
I9X38_01075	COG1447	Phosphotransferase system cellobiose-specific component IIA
I9X38_01080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I9X38_01085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I9X38_01090	COG3711	transcriptional antiterminator
I9X38_01090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_01100	COG2094	Belongs to the DNA glycosylase MPG family
I9X38_01105	COG0753	catalase activity
I9X38_01110	COG2814	Major facilitator Superfamily
I9X38_01115	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I9X38_01120	COG1131	(ABC) transporter
I9X38_01140	COG1595	DNA-templated transcription, initiation
I9X38_01145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I9X38_01150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I9X38_01155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
I9X38_01160	COG4988	ABC transporter
I9X38_01165	COG1294	oxidase, subunit
I9X38_01170	COG1271	oxidase subunit
I9X38_01175	COG3493	citrate carrier protein
I9X38_01180	COG0501	Belongs to the peptidase M48B family
I9X38_01190	COG0726	polysaccharide deacetylase
I9X38_01200	COG3842	ATPase activity
I9X38_01205	COG2508	Transcriptional regulator
I9X38_01210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_01220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I9X38_01235	COG2195	Cleaves the N-terminal amino acid of tripeptides
I9X38_01245	COG4894	glucomannan catabolic process
I9X38_01250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I9X38_01255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I9X38_01260	COG3290	protein histidine kinase activity
I9X38_01260	COG3829	transcription factor binding
I9X38_01265	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_01270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I9X38_01275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I9X38_01280	COG2610	gluconate transmembrane transporter activity
I9X38_01285	COG0500	methyltransferase
I9X38_01290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I9X38_01305	COG0753	catalase activity
I9X38_01305	COG0693	protein deglycase activity
I9X38_01310	COG2851	Citrate transporter
I9X38_01320	COG2723	6-phospho-beta-galactosidase activity
I9X38_01325	COG2190	(PTS) system
I9X38_01325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_01325	COG1263	PTS System
I9X38_01330	COG3711	transcriptional antiterminator
I9X38_01340	COG2270	Major facilitator Superfamily
I9X38_01345	COG0513	Belongs to the DEAD box helicase family
I9X38_01350	COG2755	lipolytic protein G-D-S-L family
I9X38_01350	COG3401	FG-GAP repeat protein
I9X38_01410	COG0697	spore germination
I9X38_01415	COG0589	response to stress
I9X38_01420	COG2723	6-phospho-beta-galactosidase activity
I9X38_01425	COG2190	(PTS) system
I9X38_01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_01425	COG1263	PTS System
I9X38_01480	COG5444	nuclease activity
I9X38_01510	COG3507	Belongs to the glycosyl hydrolase 43 family
I9X38_01525	COG2986	histidine ammonia-lyase
I9X38_01530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
I9X38_01535	COG1228	amidohydrolase
I9X38_01540	COG0010	Belongs to the arginase family
I9X38_01545	COG0833	amino acid
I9X38_01550	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
I9X38_01555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I9X38_01560	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
I9X38_01565	COG2390	Transcriptional regulator
I9X38_01575	COG3192	ethanolamine utilization protein
I9X38_01580	COG2079	MmgE PrpD family protein
I9X38_01585	COG1473	amidohydrolase
I9X38_01590	COG1126	abc transporter atp-binding protein
I9X38_01595	COG0765	amino acid transport
I9X38_01600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I9X38_01605	COG0456	acetyltransferase
I9X38_01610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I9X38_01620	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
I9X38_01625	COG0561	phosphatase activity
I9X38_01655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I9X38_01660	COG5294	Protein conserved in bacteria
I9X38_01665	COG0577	efflux transmembrane transporter activity
I9X38_01670	COG1136	(ABC) transporter
I9X38_01675	COG2205	protein histidine kinase activity
I9X38_01680	COG0745	RESPONSE REGULATOR receiver
I9X38_01685	COG0191	fructose-bisphosphate aldolase activity
I9X38_01695	COG1082	Xylose isomerase domain protein TIM barrel
I9X38_01700	COG0673	inositol 2-dehydrogenase activity
I9X38_01705	COG2814	Major facilitator Superfamily
I9X38_01710	COG1082	Xylose isomerase domain protein TIM barrel
I9X38_01715	COG3962	Belongs to the TPP enzyme family
I9X38_01720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I9X38_01730	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_01735	COG1349	DNA-binding transcription factor activity
I9X38_01740	COG0667	Aldo Keto reductase
I9X38_01765	COG2814	Major facilitator Superfamily
I9X38_01770	COG0326	Molecular chaperone. Has ATPase activity
I9X38_01780	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_01785	COG1309	transcriptional regulator
I9X38_01790	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_01795	COG1714	RDD family
I9X38_01800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I9X38_01810	COG1714	RDD family
I9X38_01815	COG2311	Membrane
I9X38_01820	COG1917	Cupin 2, conserved barrel domain protein
I9X38_01825	COG1309	transcriptional regulator
I9X38_01830	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_01860	COG5039	Polysaccharide pyruvyl transferase
I9X38_01865	COG1929	Belongs to the glycerate kinase type-1 family
I9X38_01870	COG1802	Transcriptional regulator
I9X38_01875	COG1070	Carbohydrate kinase
I9X38_01880	COG2610	gluconate transmembrane transporter activity
I9X38_01885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I9X38_01890	COG0450	alkyl hydroperoxide reductase
I9X38_01895	COG3634	alkyl hydroperoxide reductase activity
I9X38_01920	COG1131	(ABC) transporter
I9X38_01925	COG1994	Peptidase M50
I9X38_01930	COG0535	radical SAM domain protein
I9X38_01940	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
I9X38_01945	COG0419	ATPase involved in DNA repair
I9X38_01960	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
I9X38_01975	COG1063	alcohol dehydrogenase
I9X38_01995	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
I9X38_02005	COG0457	Tetratricopeptide repeat
I9X38_02015	COG0010	Belongs to the arginase family
I9X38_02020	COG0833	amino acid
I9X38_02025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I9X38_02045	COG5658	integral membrane protein
I9X38_02050	COG0640	Transcriptional regulator
I9X38_02055	COG3829	transcription factor binding
I9X38_02060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I9X38_02065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I9X38_02070	COG4853	Protein conserved in bacteria
I9X38_02075	COG4863	YycH protein
I9X38_02080	COG5002	protein histidine kinase activity
I9X38_02085	COG0745	RESPONSE REGULATOR receiver
I9X38_02115	COG0346	lactoylglutathione lyase activity
I9X38_02120	COG0305	Participates in initiation and elongation during chromosome replication
I9X38_02135	COG3093	addiction module antidote protein HigA
I9X38_02140	COG2807	transmembrane transport
I9X38_02145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
I9X38_02150	COG0359	binds to the 23S rRNA
I9X38_02155	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
I9X38_02160	COG4241	membrane
I9X38_02170	COG5577	PFAM Coat F domain
I9X38_02175	COG1733	regulation of RNA biosynthetic process
I9X38_02180	COG1227	inorganic diphosphatase activity
I9X38_02190	COG2271	Major facilitator Superfamily
I9X38_02210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_02220	COG0640	Transcriptional regulator
I9X38_02225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I9X38_02230	COG2409	Drug exporters of the RND superfamily
I9X38_02235	COG2197	response regulator
I9X38_02240	COG4585	Histidine kinase
I9X38_02250	COG1331	Highly conserved protein containing a thioredoxin domain
I9X38_02255	COG4978	Transcriptional regulator
I9X38_02255	COG0789	Transcriptional regulator
I9X38_02260	COG1811	Na channel or pump
I9X38_02275	COG0789	Transcriptional regulator
I9X38_02280	COG0697	spore germination
I9X38_02285	COG1331	Highly conserved protein containing a thioredoxin domain
I9X38_02295	COG0789	Transcriptional regulator
I9X38_02300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_02300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02300	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_02300	COG3321	synthase
I9X38_02300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_02305	COG0300	oxidoreductase activity
I9X38_02305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02305	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_02305	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_02305	COG3321	synthase
I9X38_02310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02310	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_02310	COG3321	synthase
I9X38_02310	COG4221	oxidoreductase activity
I9X38_02315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02315	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_02315	COG3321	synthase
I9X38_02315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_02315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_02320	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_02320	COG3321	synthase
I9X38_02320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_02320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_02325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I9X38_02350	COG0187	DNA topoisomerase II activity
I9X38_02360	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I9X38_02365	COG2501	S4 domain
I9X38_02370	COG0592	DNA-directed DNA polymerase activity
I9X38_02375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
I9X38_02385	COG0594	ribonuclease P activity
I9X38_02390	COG0706	membrane insertase activity
I9X38_02395	COG1847	R3H domain protein
I9X38_02400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
I9X38_02405	COG0445	tRNA wobble uridine modification
I9X38_02410	COG0357	Ribosomal RNA small subunit methyltransferase G
I9X38_02415	COG1475	DNA binding
I9X38_02425	COG1192	Involved in chromosome partitioning
I9X38_02430	COG1475	DNA binding
I9X38_02440	COG3949	Membrane
I9X38_02445	COG4481	Protein conserved in bacteria
I9X38_02450	COG0243	molybdopterin cofactor binding
I9X38_02455	COG0012	GTP binding
I9X38_02460	COG0360	Binds together with S18 to 16S ribosomal RNA
I9X38_02465	COG0629	single-stranded DNA binding
I9X38_02475	COG0708	Exodeoxyribonuclease III
I9X38_02480	COG1609	Transcriptional regulator
I9X38_02485	COG0346	lactoylglutathione lyase activity
I9X38_02490	COG0110	maltose O-acetyltransferase activity
I9X38_02495	COG2814	Major facilitator Superfamily
I9X38_02495	COG0477	Major facilitator Superfamily
I9X38_02500	COG1266	CAAX protease self-immunity
I9X38_02505	COG1331	Highly conserved protein containing a thioredoxin domain
I9X38_02510	COG1331	Highly conserved protein containing a thioredoxin domain
I9X38_02520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_02535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02550	COG0659	secondary active sulfate transmembrane transporter activity
I9X38_02555	COG0385	Bile acid
I9X38_02560	COG2819	hydrolase of the alpha beta superfamily
I9X38_02565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_02570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_02575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I9X38_02580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I9X38_02580	COG2207	Transcriptional regulator
I9X38_02585	COG3876	Protein conserved in bacteria
I9X38_02590	COG1472	Belongs to the glycosyl hydrolase 3 family
I9X38_02595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I9X38_02600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_02600	COG1263	PTS System
I9X38_02605	COG1737	Transcriptional regulator
I9X38_02610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
I9X38_02615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_02620	COG1683	Conserved Protein
I9X38_02660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02675	COG5632	N-Acetylmuramoyl-L-alanine amidase
I9X38_02705	COG1098	S1 RNA binding domain
I9X38_02710	COG0436	Aminotransferase
I9X38_02715	COG1522	sequence-specific DNA binding
I9X38_02720	COG2267	carboxylic ester hydrolase activity
I9X38_02730	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I9X38_02735	COG2205	protein histidine kinase activity
I9X38_02745	COG5018	Exonuclease
I9X38_02750	COG2814	Major facilitator Superfamily
I9X38_02755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I9X38_02760	COG3011	Protein conserved in bacteria
I9X38_02770	COG3290	protein histidine kinase activity
I9X38_02775	COG4565	transcriptional regulatory protein
I9X38_02780	COG1744	ABC transporter substrate-binding protein PnrA-like
I9X38_02785	COG3845	ABC transporter
I9X38_02790	COG4603	Belongs to the binding-protein-dependent transport system permease family
I9X38_02795	COG1079	Belongs to the binding-protein-dependent transport system permease family
I9X38_02800	COG3493	citrate carrier protein
I9X38_02810	COG2111	Na H antiporter
I9X38_02810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I9X38_02815	COG2111	Na H antiporter
I9X38_02820	COG1006	Multisubunit Na H antiporter MnhC subunit
I9X38_02825	COG0651	ATP synthesis coupled electron transport
I9X38_02830	COG1863	multisubunit Na H antiporter MnhE subunit
I9X38_02835	COG2212	antiporter activity
I9X38_02840	COG1320	monovalent cation:proton antiporter activity
I9X38_02845	COG2050	protein possibly involved in aromatic compounds catabolism
I9X38_02850	COG2197	response regulator
I9X38_02865	COG0142	geranyltranstransferase activity
I9X38_02880	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
I9X38_02885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
I9X38_02890	COG1335	isochorismatase
I9X38_02895	COG5506	Protein of unknown function (DUF1694)
I9X38_02910	COG0628	permease
I9X38_02920	COG1418	mRNA catabolic process
I9X38_02925	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_02935	COG1511	domain protein
I9X38_02940	COG0433	COG0433 Predicted ATPase
I9X38_02940	COG1674	ftsk spoiiie
I9X38_02945	COG4499	WXG100 protein secretion system (Wss), protein YukC
I9X38_02950	COG5417	Belongs to the EsaB family
I9X38_02955	COG4842	Belongs to the WXG100 family
I9X38_02960	COG2508	Transcriptional regulator
I9X38_02960	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
I9X38_02965	COG0686	Belongs to the AlaDH PNT family
I9X38_02970	COG5634	Uncharacterized conserved protein (DUF2278)
I9X38_02975	COG3251	PFAM MbtH domain protein
I9X38_02980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_02985	COG3433	isochorismatase activity
I9X38_02985	COG1535	isochorismatase
I9X38_02990	COG1021	2,3-dihydroxybenzoate-AMP ligase
I9X38_02995	COG1169	isochorismate synthase
I9X38_03000	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_03005	COG2819	hydrolase of the alpha beta superfamily
I9X38_03010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I9X38_03015	COG1268	BioY protein
I9X38_03020	COG2056	Na+-H+ antiporter family
I9X38_03025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
I9X38_03030	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
I9X38_03035	COG3584	3D domain protein
I9X38_03050	COG1252	NADH dehydrogenase
I9X38_03055	COG0492	ferredoxin-NADP+ reductase activity
I9X38_03065	COG0516	GMP reductase activity
I9X38_03070	COG0316	Belongs to the HesB IscA family
I9X38_03075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
I9X38_03080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I9X38_03085	COG4844	belongs to the
I9X38_03090	COG1252	NADH dehydrogenase
I9X38_03095	COG4837	Protein of unknown function (DUF1462)
I9X38_03100	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
I9X38_03105	COG0823	Involved in the tonB-independent uptake of proteins
I9X38_03105	COG1506	peptidase
I9X38_03105	COG4946	Tricorn protease homolog
I9X38_03110	COG0083	homoserine kinase activity
I9X38_03115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I9X38_03120	COG0460	homoserine dehydrogenase
I9X38_03125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I9X38_03130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I9X38_03135	COG0647	UMP catabolic process
I9X38_03140	COG2445	Protein of unknown function DUF86
I9X38_03145	COG4470	Protein conserved in bacteria
I9X38_03160	COG0739	heme binding
I9X38_03170	COG3377	Domain of unknown function (DUF1805)
I9X38_03175	COG0737	Belongs to the 5'-nucleotidase family
I9X38_03180	COG0730	response to heat
I9X38_03185	COG1801	Protein of unknown function DUF72
I9X38_03195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I9X38_03200	COG2508	Transcriptional regulator
I9X38_03205	COG2233	PERMEase
I9X38_03210	COG2233	PERMEase
I9X38_03215	COG3648	Uricase
I9X38_03215	COG3195	allantoin biosynthetic process
I9X38_03220	COG2351	hydroxyisourate hydrolase activity
I9X38_03235	COG2080	2 iron, 2 sulfur cluster binding
I9X38_03240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
I9X38_03245	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
I9X38_03250	COG2068	MobA-Related Protein
I9X38_03255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
I9X38_03260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
I9X38_03265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I9X38_03270	COG2356	endonuclease I
I9X38_03275	COG3842	ATPase activity
I9X38_03280	COG2188	Transcriptional regulator
I9X38_03285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I9X38_03290	COG0395	ABC-type sugar transport system, permease component
I9X38_03295	COG1175	transmembrane transport
I9X38_03300	COG1653	transport
I9X38_03305	COG2222	sugar isomerase
I9X38_03310	COG0322	excinuclease ABC activity
I9X38_03315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I9X38_03330	COG0719	Fe-S assembly protein
I9X38_03335	COG0822	iron-sulfur transferase activity
I9X38_03340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I9X38_03345	COG0719	Fe-S assembly protein
I9X38_03350	COG0396	ATPase activity
I9X38_03360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I9X38_03365	COG1464	Belongs to the NlpA lipoprotein family
I9X38_03370	COG2011	ABC-type metal ion transport system permease component
I9X38_03375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I9X38_03385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_03390	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
I9X38_03400	COG0509	glycine decarboxylation via glycine cleavage system
I9X38_03405	COG1393	Belongs to the ArsC family
I9X38_03410	COG1960	acyl-CoA dehydrogenase activity
I9X38_03415	COG0183	Belongs to the thiolase family
I9X38_03420	COG1024	Enoyl-CoA hydratase
I9X38_03420	COG1250	3-hydroxyacyl-CoA dehydrogenase
I9X38_03430	COG0506	proline dehydrogenase activity
I9X38_03440	COG5577	PFAM Coat F domain
I9X38_03445	COG1846	Transcriptional regulator
I9X38_03450	COG0477	Major facilitator Superfamily
I9X38_03455	COG1942	4-Oxalocrotonate Tautomerase
I9X38_03460	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_03465	COG0583	DNA-binding transcription factor activity
I9X38_03475	COG1120	ATPase activity
I9X38_03490	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_03495	COG0783	Belongs to the Dps family
I9X38_03500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I9X38_03505	COG0745	RESPONSE REGULATOR receiver
I9X38_03510	COG2205	protein histidine kinase activity
I9X38_03510	COG2770	Histidine kinase
I9X38_03520	COG1309	transcriptional regulator
I9X38_03525	COG0114	fumarate hydratase activity
I9X38_03535	COG0697	spore germination
I9X38_03540	COG0814	amino acid
I9X38_03550	COG2197	response regulator
I9X38_03555	COG4585	Histidine kinase
I9X38_03560	COG4758	membrane
I9X38_03565	COG3595	metallopeptidase activity
I9X38_03570	COG1842	Phage shock protein A
I9X38_03575	COG4758	membrane
I9X38_03580	COG2814	Major facilitator Superfamily
I9X38_03585	COG2096	Adenosyltransferase
I9X38_03590	COG1120	ATPase activity
I9X38_03595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_03600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I9X38_03605	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_03610	COG3386	PFAM SMP-30 Gluconolaconase
I9X38_03615	COG2205	protein histidine kinase activity
I9X38_03620	COG0745	RESPONSE REGULATOR receiver
I9X38_03630	COG1191	sigma factor activity
I9X38_03640	COG2140	Oxalate decarboxylase
I9X38_03650	COG0577	efflux transmembrane transporter activity
I9X38_03655	COG1136	(ABC) transporter
I9X38_03660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I9X38_03665	COG1120	ATPase activity
I9X38_03670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_03675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_03680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I9X38_03685	COG0531	amino acid
I9X38_03695	COG1988	membrane-bound metal-dependent
I9X38_03700	COG1368	sulfuric ester hydrolase activity
I9X38_03705	COG1910	domain protein
I9X38_03710	COG0725	ABC transporter, periplasmic molybdate-binding protein
I9X38_03715	COG4149	molybdate abc transporter
I9X38_03720	COG0656	L-ascorbic acid biosynthetic process
I9X38_03730	COG0025	NhaP-type Na H and K H
I9X38_03735	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I9X38_03740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I9X38_03745	COG3973	AAA domain
I9X38_03755	COG2860	membrane
I9X38_03760	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
I9X38_03765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I9X38_03770	COG2217	Heavy metal translocating P-type atpase
I9X38_03775	COG2217	Heavy metal translocating P-type atpase
I9X38_03780	COG2608	mercury ion transmembrane transporter activity
I9X38_03785	COG1937	Protein conserved in bacteria
I9X38_03790	COG0673	inositol 2-dehydrogenase activity
I9X38_03795	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I9X38_03800	COG1289	transmembrane transporter activity
I9X38_03805	COG1802	Transcriptional regulator
I9X38_03810	COG0697	spore germination
I9X38_03820	COG2076	Multidrug Resistance protein
I9X38_03825	COG1309	transcriptional regulator
I9X38_03830	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_03840	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
I9X38_03845	COG0557	exoribonuclease II activity
I9X38_03850	COG1647	Serine aminopeptidase, S33
I9X38_03855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I9X38_03860	COG0596	Alpha beta hydrolase
I9X38_03865	COG1476	TRANSCRIPTIONal
I9X38_03870	COG1396	sequence-specific DNA binding
I9X38_03875	COG1396	sequence-specific DNA binding
I9X38_03880	COG1733	regulation of RNA biosynthetic process
I9X38_03885	COG0840	transmembrane signaling receptor activity
I9X38_03890	COG1174	glycine betaine transport
I9X38_03895	COG1732	Glycine betaine
I9X38_03900	COG1174	glycine betaine transport
I9X38_03905	COG0517	IMP dehydrogenase activity
I9X38_03905	COG1125	glycine betaine transport
I9X38_03910	COG1510	regulation of RNA biosynthetic process
I9X38_03915	COG1174	glycine betaine transport
I9X38_03920	COG1732	Glycine betaine
I9X38_03925	COG1174	glycine betaine transport
I9X38_03930	COG0517	IMP dehydrogenase activity
I9X38_03930	COG1125	glycine betaine transport
I9X38_03935	COG1510	regulation of RNA biosynthetic process
I9X38_03945	COG3064	Membrane
I9X38_03950	COG4640	response to antibiotic
I9X38_03955	COG0456	acetyltransferase
I9X38_03970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I9X38_03990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_03995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I9X38_04005	COG2234	aminopeptidase activity
I9X38_04015	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
I9X38_04020	COG0149	triose-phosphate isomerase activity
I9X38_04025	COG0126	phosphoglycerate kinase activity
I9X38_04035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I9X38_04040	COG2390	Transcriptional regulator
I9X38_04045	COG2814	Major facilitator Superfamily
I9X38_04050	COG1609	Transcriptional regulator
I9X38_04055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I9X38_04060	COG0583	DNA-binding transcription factor activity
I9X38_04065	COG0697	spore germination
I9X38_04070	COG1113	amino acid transport
I9X38_04075	COG3858	chitin binding
I9X38_04080	COG1556	Lactate utilization protein
I9X38_04085	COG1139	Iron-sulfur cluster binding protein
I9X38_04090	COG0247	lactate metabolic process
I9X38_04100	COG0596	Alpha beta hydrolase
I9X38_04105	COG2208	phosphoserine phosphatase activity
I9X38_04110	COG3867	Arabinogalactan endo-beta-1,4-galactanase
I9X38_04115	COG1874	Beta-galactosidase
I9X38_04120	COG3833	ABC-type maltose transport systems, permease component
I9X38_04125	COG1175	transmembrane transport
I9X38_04130	COG2182	Extracellular solute-binding protein
I9X38_04135	COG1609	Transcriptional regulator
I9X38_04140	COG2186	Transcriptional regulator
I9X38_04145	COG1620	l-lactate permease
I9X38_04150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
I9X38_04160	COG5039	Polysaccharide pyruvyl transferase
I9X38_04165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I9X38_04170	COG0110	maltose O-acetyltransferase activity
I9X38_04175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I9X38_04180	COG2244	polysaccharide biosynthetic process
I9X38_04185	COG1216	Glycosyl transferase, family 2
I9X38_04190	COG5039	Polysaccharide pyruvyl transferase
I9X38_04195	COG1216	Glycosyl transferase, family 2
I9X38_04205	COG0438	transferase activity, transferring glycosyl groups
I9X38_04210	COG1215	transferase activity, transferring glycosyl groups
I9X38_04215	COG0438	transferase activity, transferring glycosyl groups
I9X38_04220	COG1086	Polysaccharide biosynthesis protein
I9X38_04225	COG0489	protein tyrosine kinase activity
I9X38_04230	COG3944	biosynthesis protein
I9X38_04235	COG1396	sequence-specific DNA binding
I9X38_04240	COG2272	Belongs to the type-B carboxylesterase lipase family
I9X38_04250	COG3479	Phenolic acid decarboxylase
I9X38_04260	COG1794	racemase activity, acting on amino acids and derivatives
I9X38_04265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I9X38_04275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I9X38_04280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I9X38_04285	COG0640	Transcriptional regulator
I9X38_04290	COG1621	beta-fructofuranosidase activity
I9X38_04295	COG1621	beta-fructofuranosidase activity
I9X38_04300	COG0531	amino acid
I9X38_04305	COG1309	transcriptional regulator
I9X38_04310	COG2076	Multidrug Resistance protein
I9X38_04315	COG2076	Multidrug Resistance protein
I9X38_04335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I9X38_04340	COG0366	Alpha amylase catalytic
I9X38_04345	COG1554	hydrolase, family 65, central catalytic
I9X38_04350	COG5521	maltodextrose utilization protein MalA
I9X38_04355	COG3833	ABC-type maltose transport systems, permease component
I9X38_04360	COG1175	transmembrane transport
I9X38_04365	COG2182	Extracellular solute-binding protein
I9X38_04375	COG1609	Transcriptional regulator
I9X38_04380	COG1611	Belongs to the LOG family
I9X38_04385	COG1694	Mazg nucleotide pyrophosphohydrolase
I9X38_04390	COG0659	secondary active sulfate transmembrane transporter activity
I9X38_04395	COG0288	reversible hydration of carbon dioxide
I9X38_04400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I9X38_04405	COG0577	efflux transmembrane transporter activity
I9X38_04410	COG1136	(ABC) transporter
I9X38_04415	COG5002	protein histidine kinase activity
I9X38_04420	COG0745	RESPONSE REGULATOR receiver
I9X38_04430	COG2162	N-hydroxyarylamine O-acetyltransferase activity
I9X38_04435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_04440	COG1481	regulation of sporulation
I9X38_04445	COG0391	Required for morphogenesis under gluconeogenic growth conditions
I9X38_04450	COG1660	Displays ATPase and GTPase activities
I9X38_04455	COG1051	belongs to the nudix hydrolase family
I9X38_04460	COG0492	ferredoxin-NADP+ reductase activity
I9X38_04465	COG3883	PFAM NLP P60 protein
I9X38_04465	COG0791	NLP P60 protein
I9X38_04470	COG0457	Tetratricopeptide repeat
I9X38_04475	COG1132	(ABC) transporter
I9X38_04530	COG5444	nuclease activity
I9X38_04560	COG5444	nuclease activity
I9X38_04565	COG4282	regulation of fungal-type cell wall biogenesis
I9X38_04590	COG0174	glutamine synthetase
I9X38_04595	COG0789	Transcriptional regulator
I9X38_04600	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
I9X38_04605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I9X38_04610	COG0464	growth
I9X38_04615	COG1131	(ABC) transporter
I9X38_04620	COG0860	N-Acetylmuramoyl-L-alanine amidase
I9X38_04625	COG4112	unkown
I9X38_04630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I9X38_04635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I9X38_04640	COG1780	Probably involved in ribonucleotide reductase function
I9X38_04660	COG1923	regulation of RNA biosynthetic process
I9X38_04665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
I9X38_04690	COG1764	response to oxidative stress
I9X38_04695	COG4195	phage-related replication protein
I9X38_04700	COG1404	Belongs to the peptidase S8 family
I9X38_04710	COG2124	cytochrome p450
I9X38_04715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I9X38_04715	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I9X38_04715	COG3321	synthase
I9X38_04715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_04725	COG0300	oxidoreductase activity
I9X38_04725	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_04725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_04725	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_04725	COG3321	synthase
I9X38_04730	COG4221	oxidoreductase activity
I9X38_04730	COG3321	synthase
I9X38_04730	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_04730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_04740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_04750	COG4221	oxidoreductase activity
I9X38_04750	COG3321	synthase
I9X38_04750	COG0300	oxidoreductase activity
I9X38_04750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_04770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_04800	COG1476	TRANSCRIPTIONal
I9X38_04810	COG3239	Fatty acid desaturase
I9X38_04815	COG1278	Cold shock
I9X38_04825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_04825	COG0300	oxidoreductase activity
I9X38_04825	COG3321	synthase
I9X38_04825	COG4221	oxidoreductase activity
I9X38_04855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I9X38_04860	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
I9X38_04865	COG0010	Belongs to the arginase family
I9X38_04875	COG0457	Tetratricopeptide repeat
I9X38_04880	COG3391	amine dehydrogenase activity
I9X38_04905	COG0612	Peptidase, M16
I9X38_04915	COG1131	(ABC) transporter
I9X38_04925	COG0535	radical SAM domain protein
I9X38_04935	COG4506	Protein conserved in bacteria
I9X38_04940	COG0018	arginyl-trna synthetase
I9X38_04945	COG2223	nitrite transmembrane transporter activity
I9X38_04950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I9X38_04960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I9X38_04965	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I9X38_04970	COG1140	nitrate reductase beta subunit
I9X38_04975	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I9X38_04980	COG2181	nitrate reductase activity
I9X38_04990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I9X38_04995	COG1132	(ABC) transporter
I9X38_05005	COG1476	TRANSCRIPTIONal
I9X38_05015	COG4294	response to UV
I9X38_05020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I9X38_05025	COG0247	lactate metabolic process
I9X38_05025	COG2181	nitrate reductase activity
I9X38_05030	COG1960	acyl-CoA dehydrogenase activity
I9X38_05035	COG3343	RNA polymerase activity
I9X38_05040	COG0504	CTP synthase activity
I9X38_05045	COG4821	SIS domain
I9X38_05050	COG2204	response regulator
I9X38_05055	COG0191	fructose-bisphosphate aldolase activity
I9X38_05060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I9X38_05065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I9X38_05070	COG1494	fructose-1,6-bisphosphatase
I9X38_05080	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I9X38_05090	COG1435	thymidine kinase activity
I9X38_05095	COG0281	malic enzyme
I9X38_05100	COG0679	Auxin Efflux Carrier
I9X38_05105	COG0789	Transcriptional regulator
I9X38_05110	COG0346	lactoylglutathione lyase activity
I9X38_05115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
I9X38_05120	COG2890	protein-(glutamine-N5) methyltransferase activity
I9X38_05140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
I9X38_05145	COG0009	L-threonylcarbamoyladenylate synthase
I9X38_05150	COG1971	Probably functions as a manganese efflux pump
I9X38_05155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I9X38_05160	COG0698	ribose 5-phosphate isomerase
I9X38_05165	COG4475	Protein of unknown function (DUF436)
I9X38_05170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
I9X38_05175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
I9X38_05185	COG0356	it plays a direct role in the translocation of protons across the membrane
I9X38_05195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
I9X38_05200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
I9X38_05210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
I9X38_05215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
I9X38_05220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
I9X38_05230	COG4836	Membrane
I9X38_05240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I9X38_05245	COG2385	sporulation resulting in formation of a cellular spore
I9X38_05250	COG2304	oxidoreductase activity
I9X38_05255	COG2304	oxidoreductase activity
I9X38_05265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
I9X38_05270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
I9X38_05275	COG0457	Tetratricopeptide repeat
I9X38_05280	COG1994	Peptidase M50
I9X38_05285	COG3237	CsbD-like
I9X38_05315	COG0831	urea catabolic process
I9X38_05320	COG0832	Belongs to the urease beta subunit family
I9X38_05325	COG0804	urea catabolic process
I9X38_05330	COG1959	2 iron, 2 sulfur cluster binding
I9X38_05335	COG2910	NAD(P)H-binding
I9X38_05345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I9X38_05360	COG1247	-acetyltransferase
I9X38_05365	COG0739	heme binding
I9X38_05375	COG0671	phosphoesterase, PA-phosphatase related
I9X38_05380	COG0347	Belongs to the P(II) protein family
I9X38_05385	COG0004	ammonium transporteR
I9X38_05395	COG1335	isochorismatase
I9X38_05400	COG0477	Major facilitator Superfamily
I9X38_05405	COG1953	Uracil, thiamine, allantoin
I9X38_05410	COG3420	alginic acid biosynthetic process
I9X38_05415	COG2814	Major facilitator Superfamily
I9X38_05420	COG1846	Transcriptional regulator
I9X38_05430	COG1609	Transcriptional regulator
I9X38_05435	COG1077	Cell shape determining protein MreB Mrl
I9X38_05440	COG4786	Flagellar basal body rod
I9X38_05445	COG4786	Flagellar basal body rod
I9X38_05450	COG0457	Tetratricopeptide repeat
I9X38_05455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
I9X38_05460	COG1970	mechanosensitive ion channel activity
I9X38_05465	COG2602	Beta-lactamase
I9X38_05480	COG0629	single-stranded DNA binding
I9X38_05485	COG1349	DNA-binding transcription factor activity
I9X38_05490	COG0561	phosphatase activity
I9X38_05495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I9X38_05500	COG4715	Zinc finger, swim domain protein
I9X38_05510	COG3944	biosynthesis protein
I9X38_05515	COG0489	protein tyrosine kinase activity
I9X38_05520	COG4464	protein tyrosine phosphatase activity
I9X38_05525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I9X38_05545	COG5444	nuclease activity
I9X38_05585	COG2059	Chromate
I9X38_05590	COG2059	Chromate
I9X38_05595	COG1522	sequence-specific DNA binding
I9X38_05600	COG0405	Gamma-glutamyltransferase
I9X38_05610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I9X38_05625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_05630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I9X38_05640	COG5337	Spore coat protein CotH
I9X38_05660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_05665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_05670	COG2721	sulfolactate sulfo-lyase activity
I9X38_05705	COG1595	DNA-templated transcription, initiation
I9X38_05710	COG5662	AntiSigma factor
I9X38_05715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
I9X38_05720	COG4856	YbbR-like protein
I9X38_05725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I9X38_05730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I9X38_05740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I9X38_05745	COG3002	Belongs to the UPF0753 family
I9X38_05750	COG0288	reversible hydration of carbon dioxide
I9X38_05760	COG5609	conserved protein (DUF2294)
I9X38_05765	COG0640	Transcriptional regulator
I9X38_05770	COG2814	Major facilitator Superfamily
I9X38_05785	COG0789	Transcriptional regulator
I9X38_05790	COG0596	Alpha beta hydrolase
I9X38_05800	COG0642	Histidine kinase
I9X38_05810	COG0515	serine threonine protein kinase
I9X38_05825	COG1113	amino acid transport
I9X38_05840	COG2602	Beta-lactamase
I9X38_05845	COG2124	cytochrome p450
I9X38_05855	COG0531	amino acid
I9X38_05860	COG0584	glycerophosphoryl diester phosphodiesterase
I9X38_05865	COG2271	Major facilitator Superfamily
I9X38_05875	COG1846	Transcriptional regulator
I9X38_05875	COG0456	acetyltransferase
I9X38_05880	COG2271	Major facilitator Superfamily
I9X38_05890	COG0697	spore germination
I9X38_05895	COG2207	Transcriptional regulator
I9X38_05895	COG1917	Cupin 2, conserved barrel domain protein
I9X38_05900	COG0371	Dehydrogenase
I9X38_05905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
I9X38_05910	COG3591	Belongs to the peptidase S1B family
I9X38_05920	COG0596	Alpha beta hydrolase
I9X38_05925	COG1183	phosphatidylcholine synthase activity
I9X38_05930	COG0586	Pfam SNARE associated Golgi protein
I9X38_05935	COG0688	phosphatidylethanolamine metabolic process
I9X38_05945	COG2312	Erythromycin esterase
I9X38_05950	COG2207	Transcriptional regulator
I9X38_05955	COG1054	Belongs to the UPF0176 family
I9X38_05960	COG1301	dicarboxylic acid transport
I9X38_05965	COG2190	(PTS) system
I9X38_05965	COG1263	PTS System
I9X38_05965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_05970	COG0363	glucosamine-6-phosphate deaminase activity
I9X38_05975	COG2188	Transcriptional regulator
I9X38_05985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I9X38_05990	COG0833	amino acid
I9X38_05995	COG2040	homocysteine
I9X38_06000	COG1115	amino acid carrier protein
I9X38_06005	COG2066	Belongs to the glutaminase family
I9X38_06010	COG4191	Histidine kinase
I9X38_06015	COG0784	Response regulator, receiver
I9X38_06020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I9X38_06025	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_06030	COG2271	Major facilitator Superfamily
I9X38_06035	COG4948	Mandelate Racemase Muconate Lactonizing
I9X38_06040	COG2186	Transcriptional regulator
I9X38_06045	COG2721	sulfolactate sulfo-lyase activity
I9X38_06050	COG3173	Aminoglycoside phosphotransferase
I9X38_06060	COG0697	spore germination
I9X38_06065	COG0745	RESPONSE REGULATOR receiver
I9X38_06070	COG2205	protein histidine kinase activity
I9X38_06075	COG1131	(ABC) transporter
I9X38_06095	COG3773	Cell wall hydrolase
I9X38_06100	COG2304	oxidoreductase activity
I9X38_06110	COG3540	Alkaline phosphatase
I9X38_06115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I9X38_06120	COG0805	protein transport
I9X38_06125	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
I9X38_06130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I9X38_06135	COG0477	Major facilitator Superfamily
I9X38_06140	COG1309	transcriptional regulator
I9X38_06145	COG0252	asparaginase activity
I9X38_06150	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
I9X38_06155	COG1714	RDD family
I9X38_06160	COG1405	negative regulation of cell septum assembly
I9X38_06160	COG3012	SEC-C Motif Domain Protein
I9X38_06165	COG3290	protein histidine kinase activity
I9X38_06170	COG3279	Response regulator of the LytR AlgR family
I9X38_06175	COG4555	ABC transporter
I9X38_06180	COG1668	transmembrane transport
I9X38_06185	COG0667	Aldo Keto reductase
I9X38_06200	COG1595	DNA-templated transcription, initiation
I9X38_06205	COG1595	DNA-templated transcription, initiation
I9X38_06210	COG1876	peptidase activity
I9X38_06215	COG0457	Tetratricopeptide repeat
I9X38_06220	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_06225	COG0366	Alpha amylase catalytic
I9X38_06230	COG0803	Belongs to the bacterial solute-binding protein 9 family
I9X38_06235	COG1121	(ABC) transporter
I9X38_06240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I9X38_06245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I9X38_06250	COG2310	stress, protein
I9X38_06255	COG2310	stress, protein
I9X38_06260	COG2310	stress, protein
I9X38_06265	COG0861	Integral membrane protein TerC family
I9X38_06280	COG1358	cellular component organization or biogenesis
I9X38_06295	COG3853	Toxic anion resistance protein (TelA)
I9X38_06300	COG0477	Major facilitator Superfamily
I9X38_06305	COG2814	Major facilitator Superfamily
I9X38_06310	COG0640	Transcriptional regulator
I9X38_06315	COG4175	Glycine betaine
I9X38_06315	COG0517	IMP dehydrogenase activity
I9X38_06320	COG4176	ABC-type proline glycine betaine transport system permease component
I9X38_06325	COG2113	Glycine betaine
I9X38_06330	COG1473	amidohydrolase
I9X38_06335	COG1288	antiporter activity
I9X38_06345	COG0366	Alpha amylase catalytic
I9X38_06350	COG0039	L-malate dehydrogenase activity
I9X38_06355	COG1620	l-lactate permease
I9X38_06360	COG2814	Major facilitator Superfamily
I9X38_06365	COG1846	Transcriptional regulator
I9X38_06370	COG1280	lysine exporter protein (LysE YggA)
I9X38_06375	COG3403	YqcI/YcgG family
I9X38_06380	COG1113	amino acid transport
I9X38_06385	COG3665	Urea carboxylase-associated protein
I9X38_06390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
I9X38_06395	COG1660	Displays ATPase and GTPase activities
I9X38_06405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
I9X38_06415	COG3458	cephalosporin-C deacetylase activity
I9X38_06420	COG3541	Predicted nucleotidyltransferase
I9X38_06425	COG0506	proline dehydrogenase activity
I9X38_06430	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_06435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I9X38_06440	COG2508	Transcriptional regulator
I9X38_06445	COG3689	TIGRFAM TIGR03943 family protein
I9X38_06450	COG0701	Predicted permease
I9X38_06455	COG2267	carboxylic ester hydrolase activity
I9X38_06460	COG0492	ferredoxin-NADP+ reductase activity
I9X38_06465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I9X38_06465	COG1587	Uroporphyrinogen-III synthase
I9X38_06470	COG2146	nitrite reductase [NAD(P)H] activity
I9X38_06475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I9X38_06480	COG0243	molybdopterin cofactor binding
I9X38_06485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I9X38_06490	COG2223	nitrite transmembrane transporter activity
I9X38_06495	COG1469	GTP cyclohydrolase I activity
I9X38_06500	COG1376	ErfK ybiS ycfS ynhG family protein
I9X38_06510	COG0523	cobalamin synthesis protein
I9X38_06515	COG0765	amino acid transport
I9X38_06520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I9X38_06525	COG1063	alcohol dehydrogenase
I9X38_06530	COG1714	RDD family
I9X38_06540	COG1846	Transcriptional regulator
I9X38_06550	COG3842	ATPase activity
I9X38_06555	COG2723	6-phospho-beta-galactosidase activity
I9X38_06565	COG3209	COG3209 Rhs family protein
I9X38_06570	COG0840	transmembrane signaling receptor activity
I9X38_06570	COG3290	protein histidine kinase activity
I9X38_06575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
I9X38_06580	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I9X38_06585	COG1733	regulation of RNA biosynthetic process
I9X38_06595	COG4221	oxidoreductase activity
I9X38_06595	COG3321	synthase
I9X38_06595	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_06595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_06600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_06600	COG3321	synthase
I9X38_06600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_06600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_06600	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_06605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_06605	COG0300	oxidoreductase activity
I9X38_06605	COG3321	synthase
I9X38_06605	COG4221	oxidoreductase activity
I9X38_06635	COG2072	flavoprotein involved in K transport
I9X38_06650	COG2249	NAD(P)H dehydrogenase (quinone) activity
I9X38_06660	COG3764	Sortase (surface protein transpeptidase)
I9X38_06665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_06675	COG5444	nuclease activity
I9X38_06680	COG5444	nuclease activity
I9X38_06695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_06695	COG4221	oxidoreductase activity
I9X38_06695	COG3321	synthase
I9X38_06695	COG0300	oxidoreductase activity
I9X38_06700	COG3321	synthase
I9X38_06700	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_06700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_06700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_06700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_06705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_06720	COG4463	regulation of RNA biosynthetic process
I9X38_06725	COG3880	PFAM UvrB UvrC protein
I9X38_06730	COG3869	Catalyzes the specific phosphorylation of arginine residues in
I9X38_06735	COG0542	response to heat
I9X38_06740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
I9X38_06745	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
I9X38_06750	COG4956	integral membrane protein (PIN domain superfamily)
I9X38_06755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
I9X38_06760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
I9X38_06765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
I9X38_06770	COG1045	serine acetyltransferase
I9X38_06775	COG0215	cysteine-tRNA ligase activity
I9X38_06780	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
I9X38_06785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I9X38_06790	COG3688	RNA-binding protein containing a PIN domain
I9X38_06795	COG1595	DNA-templated transcription, initiation
I9X38_06805	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I9X38_06810	COG0250	Participates in transcription elongation, termination and antitermination
I9X38_06820	COG0081	regulation of translation
I9X38_06835	COG2813	Specifically methylates the guanine in position
I9X38_06840	COG0085	RNA polymerase activity
I9X38_06845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
I9X38_06850	COG1358	cellular component organization or biogenesis
I9X38_06860	COG0049	tRNA binding
I9X38_06865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
I9X38_06870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
I9X38_06875	COG0596	Alpha beta hydrolase
I9X38_06885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
I9X38_06900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
I9X38_06920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
I9X38_06930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
I9X38_06935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
I9X38_06945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
I9X38_06955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
I9X38_06960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
I9X38_06965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
I9X38_06980	COG0200	Binds to the 23S rRNA
I9X38_06985	COG0201	protein transport
I9X38_06990	COG0563	adenylate kinase activity
I9X38_06995	COG0024	Methionine aminopeptidase
I9X38_07005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
I9X38_07015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
I9X38_07020	COG0202	RNA polymerase activity
I9X38_07025	COG0203	ribosomal protein L17
I9X38_07030	COG1122	ATPase activity
I9X38_07035	COG1122	ATPase activity
I9X38_07040	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I9X38_07045	COG0101	tRNA pseudouridine synthase activity
I9X38_07050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
I9X38_07065	COG2226	methyltransferase
I9X38_07075	COG0860	N-Acetylmuramoyl-L-alanine amidase
I9X38_07080	COG0489	protein tyrosine kinase activity
I9X38_07090	COG2194	sulfuric ester hydrolase activity
I9X38_07095	COG0726	polysaccharide deacetylase
I9X38_07110	COG1609	Transcriptional regulator
I9X38_07120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_07130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
I9X38_07135	COG1316	TRANSCRIPTIONal
I9X38_07145	COG2385	sporulation resulting in formation of a cellular spore
I9X38_07145	COG2247	cell wall binding repeat
I9X38_07150	COG0860	N-Acetylmuramoyl-L-alanine amidase
I9X38_07150	COG2247	cell wall binding repeat
I9X38_07160	COG2244	polysaccharide biosynthetic process
I9X38_07165	COG0297	glycogen (starch) synthase activity
I9X38_07165	COG0438	transferase activity, transferring glycosyl groups
I9X38_07170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I9X38_07175	COG3307	-O-antigen
I9X38_07180	COG3206	protein involved in exopolysaccharide biosynthesis
I9X38_07185	COG1215	transferase activity, transferring glycosyl groups
I9X38_07190	COG0438	transferase activity, transferring glycosyl groups
I9X38_07195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I9X38_07200	COG1316	TRANSCRIPTIONal
I9X38_07205	COG1739	Uncharacterized protein family UPF0029
I9X38_07210	COG4585	Histidine kinase
I9X38_07215	COG2197	response regulator
I9X38_07220	COG1307	EDD domain protein, DegV family
I9X38_07225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
I9X38_07235	COG1040	competence protein
I9X38_07245	COG2747	anti-sigma28 factor FlgM
I9X38_07250	COG3418	PFAM FlgN family protein
I9X38_07255	COG4786	Flagellar basal body rod
I9X38_07255	COG1256	bacterial-type flagellum assembly
I9X38_07260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I9X38_07270	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
I9X38_07275	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I9X38_07280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I9X38_07285	COG1334	flagellar protein FlaG
I9X38_07290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
I9X38_07295	COG1516	flagellar protein fliS
I9X38_07310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I9X38_07315	COG0653	protein targeting
I9X38_07325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_07330	COG2010	Cytochrome c
I9X38_07335	COG2884	Cell division ATP-binding protein ftsE
I9X38_07340	COG2177	Part of the ABC transporter FtsEX involved in
I9X38_07345	COG3409	Peptidoglycan-binding domain 1 protein
I9X38_07345	COG0793	Belongs to the peptidase S41A family
I9X38_07355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I9X38_07360	COG2814	Major facilitator Superfamily
I9X38_07365	COG1309	transcriptional regulator
I9X38_07370	COG0574	Belongs to the PEP-utilizing enzyme family
I9X38_07370	COG3848	Pyruvate phosphate dikinase
I9X38_07375	COG4897	Protein conserved in bacteria
I9X38_07385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
I9X38_07400	COG3595	metallopeptidase activity
I9X38_07405	COG1983	PspC domain protein
I9X38_07410	COG1950	PFAM Membrane protein of
I9X38_07415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I9X38_07420	COG2188	Transcriptional regulator
I9X38_07425	COG0363	glucosamine-6-phosphate deaminase activity
I9X38_07430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I9X38_07435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
I9X38_07440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
I9X38_07445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
I9X38_07450	COG0546	phosphoglycolate phosphatase activity
I9X38_07455	COG0110	maltose O-acetyltransferase activity
I9X38_07460	COG5297	Belongs to the glycosyl hydrolase family 6
I9X38_07465	COG4990	cell redox homeostasis
I9X38_07470	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
I9X38_07475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
I9X38_07480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
I9X38_07485	COG0131	Imidazoleglycerol-phosphate dehydratase
I9X38_07490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
I9X38_07495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
I9X38_07500	COG0107	imidazoleglycerol-phosphate synthase activity
I9X38_07505	COG0140	phosphoribosyl-ATP diphosphatase activity
I9X38_07505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
I9X38_07515	COG1250	3-hydroxyacyl-CoA dehydrogenase
I9X38_07560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_07560	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_07560	COG4221	oxidoreductase activity
I9X38_07560	COG3321	synthase
I9X38_07580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
I9X38_07585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I9X38_07590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I9X38_07595	COG0297	glycogen (starch) synthase activity
I9X38_07600	COG0058	SHG alpha-glucan phosphorylase activity
I9X38_07605	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
I9X38_07610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I9X38_07615	COG1169	isochorismate synthase
I9X38_07620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
I9X38_07625	COG0596	Alpha beta hydrolase
I9X38_07630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
I9X38_07635	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_07640	COG4948	Mandelate Racemase Muconate Lactonizing
I9X38_07645	COG0803	Belongs to the bacterial solute-binding protein 9 family
I9X38_07650	COG1121	(ABC) transporter
I9X38_07655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I9X38_07655	COG1321	iron dependent repressor
I9X38_07660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I9X38_07670	COG1294	oxidase, subunit
I9X38_07675	COG1271	oxidase subunit
I9X38_07680	COG0254	rRNA binding
I9X38_07685	COG0288	reversible hydration of carbon dioxide
I9X38_07690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
I9X38_07695	COG1854	S-ribosylhomocysteine lyase activity
I9X38_07710	COG0783	Belongs to the Dps family
I9X38_07715	COG4824	toxin secretion phage lysis holin
I9X38_07720	COG0494	nUDIX hydrolase
I9X38_07725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I9X38_07730	COG1116	anion transmembrane transporter activity
I9X38_07735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I9X38_07740	COG1506	peptidase
I9X38_07750	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
I9X38_07755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
I9X38_07760	COG0367	asparagine synthase
I9X38_07765	COG1113	amino acid transport
I9X38_07770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I9X38_07775	COG2267	carboxylic ester hydrolase activity
I9X38_07785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
I9X38_07790	COG1242	4 iron, 4 sulfur cluster binding
I9X38_07805	COG1725	Transcriptional regulator
I9X38_07810	COG1131	(ABC) transporter
I9X38_07825	COG1136	(ABC) transporter
I9X38_07830	COG0577	efflux transmembrane transporter activity
I9X38_07835	COG0745	RESPONSE REGULATOR receiver
I9X38_07840	COG2205	protein histidine kinase activity
I9X38_07845	COG1136	(ABC) transporter
I9X38_07850	COG0577	efflux transmembrane transporter activity
I9X38_07855	COG2433	Pfam Transposase IS66
I9X38_07860	COG2814	Major facilitator Superfamily
I9X38_07865	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_07865	COG2202	Pas domain
I9X38_07875	COG0495	leucyl-tRNA aminoacylation
I9X38_07880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I9X38_07885	COG1486	melibiose metabolic process
I9X38_07890	COG0395	ABC-type sugar transport system, permease component
I9X38_07895	COG1175	transmembrane transport
I9X38_07900	COG1653	transport
I9X38_07905	COG1609	Transcriptional regulator
I9X38_07910	COG1073	alpha beta
I9X38_07920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I9X38_07925	COG0156	8-amino-7-oxononanoate synthase activity
I9X38_07935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
I9X38_07940	COG2124	cytochrome p450
I9X38_07945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_07950	COG0395	ABC-type sugar transport system, permease component
I9X38_07955	COG1653	transport
I9X38_07960	COG2207	Transcriptional regulator
I9X38_07965	COG4209	transmembrane transport
I9X38_07970	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
I9X38_07975	COG1653	transport
I9X38_07980	COG0673	inositol 2-dehydrogenase activity
I9X38_07985	COG5578	integral membrane protein
I9X38_07995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I9X38_08000	COG2081	HI0933 family
I9X38_08005	COG2244	polysaccharide biosynthetic process
I9X38_08010	COG1187	pseudouridine synthase activity
I9X38_08015	COG1349	DNA-binding transcription factor activity
I9X38_08020	COG1131	(ABC) transporter
I9X38_08025	COG4473	ABC transporter
I9X38_08030	COG2252	PERMEase
I9X38_08035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I9X38_08040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I9X38_08045	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I9X38_08055	COG1597	lipid kinase activity
I9X38_08060	COG1523	belongs to the glycosyl hydrolase 13 family
I9X38_08065	COG0510	thiamine kinase activity
I9X38_08075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
I9X38_08080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_08085	COG0281	malic enzyme
I9X38_08090	COG5584	Small secreted protein
I9X38_08095	COG1363	Peptidase, m42
I9X38_08110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_08115	COG4848	Belongs to the UPF0354 family
I9X38_08120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I9X38_08125	COG1674	ftsk spoiiie
I9X38_08130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I9X38_08135	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
I9X38_08140	COG4980	gas vesicle protein
I9X38_08145	COG3118	belongs to the thioredoxin family
I9X38_08150	COG1605	Chorismate mutase
I9X38_08150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
I9X38_08155	COG1609	Transcriptional regulator
I9X38_08160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I9X38_08165	COG1360	Flagellar Motor Protein
I9X38_08170	COG0123	including yeast histone deacetylase and acetoin utilization protein
I9X38_08175	COG0517	IMP dehydrogenase activity
I9X38_08180	COG0454	-acetyltransferase
I9X38_08185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I9X38_08190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
I9X38_08200	COG2203	Gaf domain
I9X38_08200	COG2199	diguanylate cyclase activity
I9X38_08205	COG1956	GAF domain-containing protein
I9X38_08210	COG1309	transcriptional regulator
I9X38_08215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I9X38_08220	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
I9X38_08225	COG1114	Component of the transport system for branched-chain amino acids
I9X38_08230	COG1104	cysteine desulfurase activity
I9X38_08235	COG0301	tRNA thio-modification
I9X38_08245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
I9X38_08250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
I9X38_08255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
I9X38_08260	COG0616	signal peptide processing
I9X38_08265	COG1714	RDD family
I9X38_08275	COG3874	Sporulation protein YtfJ
I9X38_08280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
I9X38_08285	COG0827	DNA restriction-modification system
I9X38_08290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
I9X38_08295	COG0521	Mo-molybdopterin cofactor biosynthetic process
I9X38_08300	COG0137	argininosuccinate synthase activity
I9X38_08305	COG0165	Argininosuccinate lyase
I9X38_08310	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_08315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I9X38_08320	COG4109	DRTGG domain
I9X38_08330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
I9X38_08350	COG0587	DNA-directed DNA polymerase activity
I9X38_08355	COG0281	malic enzyme
I9X38_08360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
I9X38_08365	COG0825	malonyl-CoA metabolic process
I9X38_08370	COG0205	6-phosphofructokinase activity
I9X38_08375	COG0469	pyruvate kinase activity
I9X38_08380	COG3030	protein affecting phage T7 exclusion by the F plasmid
I9X38_08385	COG0628	permease
I9X38_08390	COG2707	UPF0756 membrane protein
I9X38_08395	COG0372	Belongs to the citrate synthase family
I9X38_08400	COG0538	isocitrate dehydrogenase activity
I9X38_08405	COG0039	L-malate dehydrogenase activity
I9X38_08410	COG0745	RESPONSE REGULATOR receiver
I9X38_08415	COG5002	protein histidine kinase activity
I9X38_08420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I9X38_08420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I9X38_08425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I9X38_08430	COG1971	Probably functions as a manganese efflux pump
I9X38_08435	COG0237	dephospho-CoA kinase activity
I9X38_08440	COG0656	L-ascorbic acid biosynthetic process
I9X38_08445	COG2814	Major facilitator Superfamily
I9X38_08450	COG1733	regulation of RNA biosynthetic process
I9X38_08455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I9X38_08460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
I9X38_08465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I9X38_08470	COG3611	Membrane attachment protein
I9X38_08475	COG1484	DNA-dependent DNA replication
I9X38_08480	COG0398	Pfam SNARE associated Golgi protein
I9X38_08490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I9X38_08495	COG1011	Hydrolase
I9X38_08500	COG3275	phosphorelay sensor kinase activity
I9X38_08505	COG3279	Response regulator of the LytR AlgR family
I9X38_08510	COG1380	Effector of murein hydrolase LrgA
I9X38_08515	COG1346	cytolysis
I9X38_08530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
I9X38_08535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
I9X38_08540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
I9X38_08545	COG3326	Membrane
I9X38_08555	COG1363	Peptidase, m42
I9X38_08560	COG3507	Belongs to the glycosyl hydrolase 43 family
I9X38_08565	COG2160	L-arabinose isomerase activity
I9X38_08570	COG1069	ribulokinase activity
I9X38_08575	COG0235	Class ii aldolase
I9X38_08580	COG0647	UMP catabolic process
I9X38_08585	COG0371	Dehydrogenase
I9X38_08590	COG1653	transport
I9X38_08595	COG1175	transmembrane transport
I9X38_08600	COG0395	ABC-type sugar transport system, permease component
I9X38_08605	COG3534	alpha-L-arabinofuranosidase
I9X38_08610	COG1695	Transcriptional regulator
I9X38_08625	COG1966	Carbon starvation protein
I9X38_08630	COG0346	lactoylglutathione lyase activity
I9X38_08635	COG0247	lactate metabolic process
I9X38_08640	COG0277	FAD linked oxidase domain protein
I9X38_08645	COG3835	regulator
I9X38_08655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I9X38_08665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
I9X38_08670	COG0072	phenylalanine-tRNA ligase activity
I9X38_08670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I9X38_08675	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
I9X38_08680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
I9X38_08685	COG1286	toxin biosynthetic process
I9X38_08690	COG1796	DNA polymerase
I9X38_08690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
I9X38_08695	COG1193	negative regulation of DNA recombination
I9X38_08700	COG3766	membrane
I9X38_08705	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_08710	COG1309	transcriptional regulator
I9X38_08715	COG1024	Enoyl-CoA hydratase
I9X38_08720	COG2086	electron transfer activity
I9X38_08725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I9X38_08730	COG3534	alpha-L-arabinofuranosidase
I9X38_08735	COG3118	belongs to the thioredoxin family
I9X38_08740	COG0322	excinuclease ABC activity
I9X38_08745	COG0527	aspartate kinase activity
I9X38_08750	COG1719	4-vinyl reductase, 4VR
I9X38_08755	COG2009	succinate dehydrogenase
I9X38_08760	COG1053	succinate dehydrogenase
I9X38_08765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I9X38_08770	COG0824	Thioesterase
I9X38_08775	COG2197	response regulator
I9X38_08780	COG1846	Transcriptional regulator
I9X38_08785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
I9X38_08790	COG5401	PFAM Sporulation and spore germination
I9X38_08795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
I9X38_08800	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
I9X38_08805	COG0622	Phosphoesterase
I9X38_08815	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
I9X38_08820	COG0454	-acetyltransferase
I9X38_08830	COG0028	Belongs to the TPP enzyme family
I9X38_08835	COG0440	acetolactate synthase activity
I9X38_08840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
I9X38_08845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I9X38_08850	COG0473	3-isopropylmalate dehydrogenase activity
I9X38_08855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
I9X38_08860	COG0066	3-isopropylmalate dehydratase activity
I9X38_08865	COG1477	protein flavinylation
I9X38_08865	COG0457	Tetratricopeptide repeat
I9X38_08870	COG0544	peptidyl-prolyl cis-trans isomerase activity
I9X38_08875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
I9X38_08880	COG0470	DNA polymerase III
I9X38_08880	COG1067	ATP-dependent peptidase activity
I9X38_08885	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I9X38_08890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
I9X38_08900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
I9X38_08905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I9X38_08910	COG0181	hydroxymethylbilane synthase activity
I9X38_08915	COG1587	Uroporphyrinogen-III synthase
I9X38_08920	COG0113	porphobilinogen synthase activity
I9X38_08925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I9X38_08945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I9X38_08950	COG0583	DNA-binding transcription factor activity
I9X38_08955	COG0028	Belongs to the TPP enzyme family
I9X38_08960	COG3527	Alpha-acetolactate decarboxylase
I9X38_08965	COG2249	NAD(P)H dehydrogenase (quinone) activity
I9X38_08975	COG3103	Sh3 type 3 domain protein
I9X38_08980	COG1879	ABC-type sugar transport system periplasmic component
I9X38_08985	COG1172	Belongs to the binding-protein-dependent transport system permease family
I9X38_08990	COG1129	ABC transporter
I9X38_08995	COG1869	D-ribose catabolic process
I9X38_09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I9X38_09005	COG1609	Transcriptional regulator
I9X38_09010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
I9X38_09020	COG2843	Capsule synthesis protein
I9X38_09030	COG0791	NLP P60 protein
I9X38_09035	COG0561	phosphatase activity
I9X38_09040	COG1316	TRANSCRIPTIONal
I9X38_09045	COG2814	Major facilitator Superfamily
I9X38_09055	COG0814	amino acid
I9X38_09060	COG0697	spore germination
I9X38_09065	COG1482	cell wall glycoprotein biosynthetic process
I9X38_09070	COG4193	domain, Protein
I9X38_09080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I9X38_09085	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
I9X38_09090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
I9X38_09095	COG0438	transferase activity, transferring glycosyl groups
I9X38_09100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I9X38_09105	COG1682	transport, permease protein
I9X38_09110	COG1134	teichoic acid transport
I9X38_09130	COG0463	Glycosyl transferase, family 2
I9X38_09135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
I9X38_09135	COG1215	transferase activity, transferring glycosyl groups
I9X38_09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_09165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_09175	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_09175	COG3321	synthase
I9X38_09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_09175	COG4221	oxidoreductase activity
I9X38_09190	COG1131	(ABC) transporter
I9X38_09195	COG0604	alcohol dehydrogenase
I9X38_09195	COG3321	synthase
I9X38_09205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I9X38_09210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_09215	COG1024	Enoyl-CoA hydratase
I9X38_09220	COG1024	Enoyl-CoA hydratase
I9X38_09225	COG3852	Histidine kinase
I9X38_09240	COG0745	RESPONSE REGULATOR receiver
I9X38_09245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I9X38_09250	COG1597	lipid kinase activity
I9X38_09255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I9X38_09260	COG1309	transcriptional regulator
I9X38_09265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
I9X38_09270	COG0154	amidase activity
I9X38_09275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
I9X38_09280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I9X38_09285	COG1285	pathogenesis
I9X38_09290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I9X38_09295	COG4851	CamS sex pheromone cAM373 precursor
I9X38_09300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
I9X38_09305	COG0210	DNA helicase
I9X38_09310	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
I9X38_09315	COG0069	glutamate synthase activity
I9X38_09320	COG4496	protein, YerC YecD
I9X38_09325	COG1470	cell adhesion involved in biofilm formation
I9X38_09330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
I9X38_09340	COG0531	amino acid
I9X38_09345	COG1522	sequence-specific DNA binding
I9X38_09350	COG0151	Belongs to the GarS family
I9X38_09355	COG0138	bifunctional purine biosynthesis protein purh
I9X38_09360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I9X38_09365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
I9X38_09370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I9X38_09375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I9X38_09380	COG0047	phosphoribosylformylglycinamidine synthase activity
I9X38_09385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I9X38_09390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
I9X38_09395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I9X38_09400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I9X38_09405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I9X38_09415	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
I9X38_09425	COG3064	Membrane
I9X38_09430	COG2252	PERMEase
I9X38_09445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
I9X38_09445	COG0519	Catalyzes the synthesis of GMP from XMP
I9X38_09450	COG1305	Transglutaminase-like
I9X38_09455	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
I9X38_09460	COG0714	Associated with various cellular activities
I9X38_09465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I9X38_09470	COG1113	amino acid transport
I9X38_09475	COG2132	Multicopper oxidase
I9X38_09485	COG2267	carboxylic ester hydrolase activity
I9X38_09500	COG0823	Involved in the tonB-independent uptake of proteins
I9X38_09505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I9X38_09510	COG1063	alcohol dehydrogenase
I9X38_09515	COG2814	Major facilitator Superfamily
I9X38_09525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I9X38_09530	COG2211	Major facilitator Superfamily
I9X38_09535	COG1063	alcohol dehydrogenase
I9X38_09540	COG0457	Tetratricopeptide repeat
I9X38_09545	COG1132	(ABC) transporter
I9X38_09560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
I9X38_09580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_09585	COG0302	gtp cyclohydrolase
I9X38_09590	COG2192	nodulation
I9X38_09595	COG0602	queuosine metabolic process
I9X38_09600	COG0720	synthase
I9X38_09635	COG1266	CAAX protease self-immunity
I9X38_09645	COG0805	protein transport
I9X38_09650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I9X38_09655	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
I9X38_09660	COG0315	cyclic pyranopterin monophosphate synthase activity
I9X38_09665	COG0488	(ABC) transporter
I9X38_09670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
I9X38_09675	COG0456	acetyltransferase
I9X38_09680	COG1214	PFAM Peptidase M22, glycoprotease
I9X38_09685	COG0802	atpase or kinase
I9X38_09690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I9X38_09775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_09775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_09775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_09775	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_09775	COG3321	synthase
I9X38_09780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_09805	COG3321	synthase
I9X38_09805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_09805	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_09805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_09815	COG0457	Tetratricopeptide repeat
I9X38_09840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_09850	COG0789	Transcriptional regulator
I9X38_09865	COG0109	protoheme IX farnesyltransferase activity
I9X38_09875	COG0726	polysaccharide deacetylase
I9X38_09890	COG5504	Zn-dependent protease
I9X38_09895	COG2205	protein histidine kinase activity
I9X38_09905	COG3383	formate dehydrogenase (NAD+) activity
I9X38_09910	COG2427	Protein of unknown function (DUF1641)
I9X38_09920	COG1051	belongs to the nudix hydrolase family
I9X38_09930	COG2124	cytochrome p450
I9X38_09935	COG1819	glycosyl
I9X38_09950	COG1587	Uroporphyrinogen-III synthase
I9X38_09955	COG0390	transport system, permease component
I9X38_09960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I9X38_09965	COG0697	spore germination
I9X38_09980	COG1252	NADH dehydrogenase
I9X38_09985	COG1904	glucuronate isomerase
I9X38_09990	COG2211	Major facilitator Superfamily
I9X38_09995	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
I9X38_10000	COG1063	alcohol dehydrogenase
I9X38_10005	COG1312	Catalyzes the dehydration of D-mannonate
I9X38_10010	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_10015	COG2271	Major facilitator Superfamily
I9X38_10020	COG1609	Transcriptional regulator
I9X38_10025	COG0246	Mannitol dehydrogenase
I9X38_10030	COG2721	sulfolactate sulfo-lyase activity
I9X38_10035	COG0730	response to heat
I9X38_10040	COG2318	DinB family
I9X38_10045	COG0457	Tetratricopeptide repeat
I9X38_10055	COG2350	Protein conserved in bacteria
I9X38_10060	COG5632	N-Acetylmuramoyl-L-alanine amidase
I9X38_10060	COG3409	Peptidoglycan-binding domain 1 protein
I9X38_10060	COG1388	LysM domain
I9X38_10070	COG4195	phage-related replication protein
I9X38_10075	COG3546	catalase activity
I9X38_10080	COG2856	Zn peptidase
I9X38_10085	COG1396	sequence-specific DNA binding
I9X38_10095	COG1522	sequence-specific DNA binding
I9X38_10100	COG1484	DNA-dependent DNA replication
I9X38_10120	COG1595	DNA-templated transcription, initiation
I9X38_10125	COG3728	DNA packaging
I9X38_10125	COG5484	DNA packaging
I9X38_10130	COG1783	phage Terminase large subunit
I9X38_10135	COG5518	Phage portal protein
I9X38_10140	COG0338	D12 class N6 adenine-specific DNA methyltransferase
I9X38_10145	COG4653	Phage capsid family
I9X38_10195	COG5412	phage tail tape measure protein
I9X38_10195	COG3953	SLT domain
I9X38_10200	COG1652	LysM domain
I9X38_10205	COG4193	domain, Protein
I9X38_10215	COG3628	GPW Gp25 family protein
I9X38_10220	COG3299	homolog of phage Mu protein gp47
I9X38_10225	COG3778	Protein conserved in bacteria
I9X38_10260	COG5632	N-Acetylmuramoyl-L-alanine amidase
I9X38_10260	COG3409	Peptidoglycan-binding domain 1 protein
I9X38_10280	COG0306	phosphate transporter
I9X38_10285	COG1392	Phosphate transport regulator
I9X38_10290	COG0531	amino acid
I9X38_10295	COG0346	lactoylglutathione lyase activity
I9X38_10300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
I9X38_10305	COG0463	Glycosyl transferase, family 2
I9X38_10315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I9X38_10320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I9X38_10325	COG2362	D-Aminopeptidase
I9X38_10330	COG0601	transmembrane transport
I9X38_10335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I9X38_10340	COG0444	Belongs to the ABC transporter superfamily
I9X38_10345	COG4166	transmembrane transport
I9X38_10350	COG1619	proteins homologs of microcin C7 resistance protein MccF
I9X38_10355	COG4948	Mandelate Racemase Muconate Lactonizing
I9X38_10360	COG0791	NLP P60 protein
I9X38_10365	COG4608	Belongs to the ABC transporter superfamily
I9X38_10370	COG2706	6-phosphogluconolactonase activity
I9X38_10375	COG1834	amidinotransferase
I9X38_10380	COG1607	acyl-coa hydrolase
I9X38_10385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I9X38_10385	COG1017	nitric oxide dioxygenase activity
I9X38_10395	COG2323	membrane
I9X38_10400	COG2318	DinB family
I9X38_10405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_10410	COG2076	Multidrug Resistance protein
I9X38_10415	COG2076	Multidrug Resistance protein
I9X38_10420	COG0788	formyltetrahydrofolate deformylase activity
I9X38_10425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I9X38_10430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
I9X38_10435	COG1764	response to oxidative stress
I9X38_10440	COG1846	Transcriptional regulator
I9X38_10445	COG1764	response to oxidative stress
I9X38_10455	COG0590	tRNA wobble adenosine to inosine editing
I9X38_10460	COG0406	alpha-ribazole phosphatase activity
I9X38_10465	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I9X38_10470	COG1404	Belongs to the peptidase S8 family
I9X38_10475	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_10480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I9X38_10485	COG1122	ATPase activity
I9X38_10490	COG4721	ABC-type cobalt transport system, permease component
I9X38_10500	COG0745	RESPONSE REGULATOR receiver
I9X38_10505	COG3850	Histidine kinase
I9X38_10505	COG5002	protein histidine kinase activity
I9X38_10510	COG3212	peptidase
I9X38_10515	COG3212	peptidase
I9X38_10525	COG2239	Acts as a magnesium transporter
I9X38_10530	COG0789	Transcriptional regulator
I9X38_10545	COG1846	Transcriptional regulator
I9X38_10550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I9X38_10555	COG0726	polysaccharide deacetylase
I9X38_10560	COG1408	metallophosphoesterase
I9X38_10570	COG0463	Glycosyl transferase, family 2
I9X38_10575	COG3285	dna ligase
I9X38_10575	COG1793	dna ligase
I9X38_10580	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
I9X38_10585	COG5001	Diguanylate cyclase
I9X38_10585	COG3300	MHYT domain
I9X38_10590	COG0586	Pfam SNARE associated Golgi protein
I9X38_10595	COG0861	Integral membrane protein TerC family
I9X38_10600	COG1191	sigma factor activity
I9X38_10620	COG0501	Belongs to the peptidase M48B family
I9X38_10625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I9X38_10640	COG3594	Acyltransferase
I9X38_10645	COG5002	protein histidine kinase activity
I9X38_10650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I9X38_10660	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
I9X38_10665	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
I9X38_10670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I9X38_10675	COG0436	Aminotransferase
I9X38_10680	COG1850	ribulose-bisphosphate carboxylase activity
I9X38_10685	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
I9X38_10690	COG0235	Class ii aldolase
I9X38_10695	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
I9X38_10700	COG3339	Conserved Protein
I9X38_10715	COG3852	Histidine kinase
I9X38_10720	COG1846	Transcriptional regulator
I9X38_10725	COG1360	Flagellar Motor Protein
I9X38_10730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I9X38_10735	COG0542	response to heat
I9X38_10740	COG3949	Membrane
I9X38_10745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
I9X38_10750	COG0720	synthase
I9X38_10755	COG0602	queuosine metabolic process
I9X38_10760	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
I9X38_10765	COG4641	Protein conserved in bacteria
I9X38_10765	COG1388	LysM domain
I9X38_10770	COG1388	LysM domain
I9X38_10775	COG3858	chitin binding
I9X38_10785	COG4873	Protein conserved in bacteria
I9X38_10795	COG3773	Cell wall hydrolase
I9X38_10800	COG2244	polysaccharide biosynthetic process
I9X38_10805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_10810	COG2217	Heavy metal translocating P-type atpase
I9X38_10820	COG0006	proline dipeptidase activity
I9X38_10825	COG1609	Transcriptional regulator
I9X38_10830	COG3711	transcriptional antiterminator
I9X38_10835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_10835	COG1263	PTS System
I9X38_10835	COG2190	(PTS) system
I9X38_10840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_10845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I9X38_10855	COG1533	DNA photolyase activity
I9X38_10860	COG0456	acetyltransferase
I9X38_10865	COG0840	transmembrane signaling receptor activity
I9X38_10870	COG2084	Dehydrogenase
I9X38_10875	COG2340	Cysteine-rich secretory protein family
I9X38_10880	COG0768	penicillin binding
I9X38_10885	COG4191	Histidine kinase
I9X38_10890	COG0436	Aminotransferase
I9X38_10900	COG0784	Response regulator, receiver
I9X38_10900	COG0835	chemotaxis
I9X38_10910	COG2814	Major facilitator Superfamily
I9X38_10915	COG1376	ErfK ybiS ycfS ynhG family protein
I9X38_10920	COG1408	metallophosphoesterase
I9X38_10925	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_10930	COG2200	EAL domain
I9X38_10935	COG3546	catalase activity
I9X38_10940	COG4703	Protein of unknown function (DUF1797)
I9X38_10945	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
I9X38_10955	COG0517	IMP dehydrogenase activity
I9X38_10960	COG0583	DNA-binding transcription factor activity
I9X38_10965	COG0716	FMN binding
I9X38_10975	COG0716	FMN binding
I9X38_10980	COG2171	N-acyltransferase activity
I9X38_10985	COG1473	amidohydrolase
I9X38_10995	COG0668	transmembrane transport
I9X38_11000	COG0450	alkyl hydroperoxide reductase
I9X38_11005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_11020	COG0746	molybdenum cofactor guanylyltransferase activity
I9X38_11025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I9X38_11030	COG0303	'Molybdopterin
I9X38_11035	COG1763	Mo-molybdopterin cofactor biosynthetic process
I9X38_11040	COG0314	molybdopterin synthase activity
I9X38_11045	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I9X38_11050	COG1132	(ABC) transporter
I9X38_11055	COG1132	(ABC) transporter
I9X38_11065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I9X38_11070	COG1136	(ABC) transporter
I9X38_11075	COG0577	efflux transmembrane transporter activity
I9X38_11080	COG1349	DNA-binding transcription factor activity
I9X38_11085	COG1105	Belongs to the carbohydrate kinase PfkB family
I9X38_11090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_11090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I9X38_11090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I9X38_11095	COG0681	Belongs to the peptidase S26 family
I9X38_11110	COG0488	(ABC) transporter
I9X38_11115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I9X38_11120	COG2309	aminopeptidase activity
I9X38_11130	COG1077	Cell shape determining protein MreB Mrl
I9X38_11135	COG2002	toxin-antitoxin pair type II binding
I9X38_11140	COG3852	Histidine kinase
I9X38_11145	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
I9X38_11145	COG2105	PFAM AIG2 family protein
I9X38_11150	COG0569	domain protein
I9X38_11155	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
I9X38_11160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I9X38_11165	COG5503	Protein of unknown function (DUF1447)
I9X38_11170	COG0561	phosphatase activity
I9X38_11175	COG0242	peptide deformylase activity
I9X38_11185	COG0497	DNA recombination
I9X38_11190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I9X38_11195	COG0022	dehydrogenase e1 component
I9X38_11200	COG0508	dehydrogenase complex catalyzes the overall conversion of
I9X38_11205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I9X38_11210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_11220	COG1982	Orn Lys Arg decarboxylase major
I9X38_11225	COG4476	Belongs to the UPF0223 family
I9X38_11230	COG4493	Belongs to the UPF0637 family
I9X38_11240	COG0483	inositol monophosphate 1-phosphatase activity
I9X38_11250	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
I9X38_11285	COG1217	gtp-binding protein TYPA
I9X38_11295	COG4896	Protein conserved in bacteria
I9X38_11305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
I9X38_11310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
I9X38_11315	COG2066	Belongs to the glutaminase family
I9X38_11320	COG4838	Belongs to the UPF0358 family
I9X38_11325	COG0772	Belongs to the SEDS family
I9X38_11330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
I9X38_11340	COG1612	heme a metabolic process
I9X38_11345	COG0109	protoheme IX farnesyltransferase activity
I9X38_11350	COG2010	Cytochrome c
I9X38_11350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I9X38_11355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I9X38_11360	COG1845	cytochrome c oxidase, subunit III
I9X38_11365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I9X38_11370	COG3336	cytochrome c oxidase
I9X38_11380	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
I9X38_11385	COG2340	Cysteine-rich secretory protein family
I9X38_11400	COG3679	Belongs to the UPF0342 family
I9X38_11405	COG4471	UPF0298 protein
I9X38_11410	COG0742	ribosomal rna small subunit methyltransferase
I9X38_11415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
I9X38_11420	COG3314	Sporulation integral membrane protein YlbJ
I9X38_11425	COG1752	Esterase of the alpha-beta hydrolase superfamily
I9X38_11430	COG3480	Lon protease (S16) C-terminal proteolytic domain
I9X38_11435	COG1323	Belongs to the UPF0348 family
I9X38_11445	COG1399	metal-binding, possibly nucleic acid-binding protein
I9X38_11460	COG0454	-acetyltransferase
I9X38_11465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
I9X38_11470	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
I9X38_11475	COG2001	Belongs to the MraZ family
I9X38_11480	COG0275	rRNA processing
I9X38_11485	COG4839	cell division protein FtsL
I9X38_11490	COG0768	penicillin binding
I9X38_11495	COG0768	penicillin binding
I9X38_11500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I9X38_11505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I9X38_11510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
I9X38_11515	COG0772	Belongs to the SEDS family
I9X38_11520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I9X38_11525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
I9X38_11530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
I9X38_11535	COG3879	Bacterial protein of unknown function (DUF881)
I9X38_11540	COG3879	Bacterial protein of unknown function (DUF881)
I9X38_11545	COG3856	small basic protein
I9X38_11550	COG0849	cell division
I9X38_11555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I9X38_11560	COG1404	Belongs to the peptidase S8 family
I9X38_11560	COG4412	M6 family metalloprotease domain protein
I9X38_11570	COG1191	sigma factor activity
I9X38_11575	COG1191	sigma factor activity
I9X38_11580	COG1119	ATPase activity
I9X38_11585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I9X38_11590	COG1873	PFAM PRC-barrel domain
I9X38_11595	COG1496	oxidoreductase activity
I9X38_11600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I9X38_11605	COG1799	cell septum assembly
I9X38_11610	COG0762	integral membrane protein
I9X38_11615	COG2302	S4 RNA-binding domain
I9X38_11620	COG3599	regulation of cell shape
I9X38_11625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
I9X38_11630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I9X38_11635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
I9X38_11640	COG0564	pseudouridine synthase activity
I9X38_11645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
I9X38_11650	COG2233	PERMEase
I9X38_11655	COG0540	Belongs to the ATCase OTCase family
I9X38_11660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I9X38_11665	COG0505	Belongs to the CarA family
I9X38_11670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I9X38_11675	COG0543	2 iron, 2 sulfur cluster binding
I9X38_11680	COG0167	dihydroorotate dehydrogenase activity
I9X38_11685	COG0284	orotidine-5'-phosphate decarboxylase activity
I9X38_11690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
I9X38_11695	COG0175	sulfate reduction
I9X38_11700	COG0306	phosphate transporter
I9X38_11705	COG2046	Belongs to the sulfate adenylyltransferase family
I9X38_11710	COG0529	Catalyzes the synthesis of activated sulfate
I9X38_11715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
I9X38_11720	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
I9X38_11725	COG1648	precorrin-2 dehydrogenase activity
I9X38_11730	COG1293	RNA-binding protein homologous to eukaryotic snRNP
I9X38_11735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I9X38_11740	COG1561	YicC-like family, N-terminal region
I9X38_11750	COG0194	GDP metabolic process
I9X38_11755	COG1758	RNA polymerase activity
I9X38_11760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I9X38_11765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I9X38_11770	COG0242	peptide deformylase activity
I9X38_11775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
I9X38_11780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I9X38_11780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I9X38_11785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
I9X38_11790	COG0631	protein serine/threonine phosphatase activity
I9X38_11795	COG0515	serine threonine protein kinase
I9X38_11795	COG2815	serine threonine protein kinase
I9X38_11800	COG1162	GTPase activity
I9X38_11805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I9X38_11810	COG1564	THIamine pyrophosphokinase
I9X38_11820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
I9X38_11825	COG1302	Protein conserved in bacteria
I9X38_11830	COG1461	Dihydroxyacetone kinase
I9X38_11835	COG1760	l-serine dehydratase
I9X38_11840	COG1760	l-serine dehydratase
I9X38_11845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I9X38_11850	COG2050	protein possibly involved in aromatic compounds catabolism
I9X38_11850	COG1349	DNA-binding transcription factor activity
I9X38_11855	COG0416	fatty acid biosynthetic process
I9X38_11860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I9X38_11865	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_11875	COG0571	ribonuclease III activity
I9X38_11880	COG1196	nuclear chromosome segregation
I9X38_11885	COG0552	protein localization to endoplasmic reticulum
I9X38_11895	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
I9X38_11900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I9X38_11905	COG0228	four-way junction DNA binding
I9X38_11910	COG1837	Belongs to the UPF0109 family
I9X38_11920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
I9X38_11925	COG0336	Belongs to the RNA methyltransferase TrmD family
I9X38_11930	COG0335	large ribosomal subunit rRNA binding
I9X38_11935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I9X38_11940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
I9X38_11950	COG2257	FlhB HrpN YscU SpaS Family
I9X38_11955	COG0045	succinate-CoA ligase (ADP-forming) activity
I9X38_11960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I9X38_11965	COG0758	DNA mediated transformation
I9X38_11970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I9X38_11975	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
I9X38_11980	COG4974	Belongs to the 'phage' integrase family
I9X38_11985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
I9X38_11990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
I9X38_11995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
I9X38_12000	COG1815	bacterial-type flagellum-dependent cell motility
I9X38_12005	COG1558	bacterial-type flagellum-dependent cell motility
I9X38_12010	COG1677	Flagellar hook-basal body complex protein FliE
I9X38_12015	COG1766	The M ring may be actively involved in energy transduction
I9X38_12020	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I9X38_12025	COG1317	bacterial-type flagellum organization
I9X38_12030	COG1157	protein secretion by the type III secretion system
I9X38_12035	COG2882	bacterial-type flagellum organization
I9X38_12040	COG3334	PFAM MgtE intracellular
I9X38_12045	COG3144	bacterial-type flagellum assembly
I9X38_12050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
I9X38_12055	COG4786	Flagellar basal body rod
I9X38_12060	COG1582	Flagellar protein (FlbD)
I9X38_12065	COG1580	Controls the rotational direction of flagella during chemotaxis
I9X38_12070	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I9X38_12075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I9X38_12075	COG1776	CheC inhibitor of MCP methylation
I9X38_12080	COG2201	protein-glutamate methylesterase activity
I9X38_12085	COG3190	flagellar
I9X38_12090	COG1338	Plays a role in the flagellum-specific transport system
I9X38_12095	COG1987	bacterial-type flagellum assembly
I9X38_12100	COG1684	flagellar biosynthetic protein fliR
I9X38_12105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I9X38_12110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
I9X38_12115	COG1419	protein localization to endoplasmic reticulum
I9X38_12120	COG0455	bacterial-type flagellum organization
I9X38_12125	COG2201	protein-glutamate methylesterase activity
I9X38_12130	COG0643	Histidine kinase
I9X38_12130	COG2198	Histidine kinase
I9X38_12135	COG0835	chemotaxis
I9X38_12140	COG1776	CheC inhibitor of MCP methylation
I9X38_12145	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
I9X38_12150	COG1191	sigma factor activity
I9X38_12160	COG0052	Belongs to the universal ribosomal protein uS2 family
I9X38_12165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
I9X38_12170	COG0528	UMP kinase activity
I9X38_12175	COG0233	cytoplasmic translational termination
I9X38_12180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
I9X38_12185	COG4589	Belongs to the CDS family
I9X38_12190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
I9X38_12195	COG0750	zinc metalloprotease
I9X38_12200	COG0442	prolyl-tRNA aminoacylation
I9X38_12205	COG2176	DNA-directed DNA polymerase activity
I9X38_12210	COG0779	Required for maturation of 30S ribosomal subunits
I9X38_12215	COG0195	Participates in both transcription termination and antitermination
I9X38_12220	COG2740	Nucleic-acid-binding protein implicated in transcription termination
I9X38_12225	COG1358	cellular component organization or biogenesis
I9X38_12230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
I9X38_12235	COG1550	Protein conserved in bacteria
I9X38_12240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
I9X38_12245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
I9X38_12250	COG0196	riboflavin kinase activity
I9X38_12260	COG1185	polyribonucleotide nucleotidyltransferase activity
I9X38_12265	COG0726	polysaccharide deacetylase
I9X38_12270	COG0612	Peptidase, M16
I9X38_12275	COG1873	PFAM PRC-barrel domain
I9X38_12280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I9X38_12285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I9X38_12290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I9X38_12295	COG0527	aspartate kinase activity
I9X38_12300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I9X38_12305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
I9X38_12310	COG0740	serine-type endopeptidase activity
I9X38_12320	COG1674	ftsk spoiiie
I9X38_12320	COG4980	gas vesicle protein
I9X38_12325	COG2188	Transcriptional regulator
I9X38_12330	COG2814	Major facilitator Superfamily
I9X38_12335	COG0612	Peptidase, M16
I9X38_12340	COG0612	Peptidase, M16
I9X38_12345	COG0300	oxidoreductase activity
I9X38_12360	COG1426	Protein conserved in bacteria
I9X38_12365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I9X38_12370	COG1058	Belongs to the CinA family
I9X38_12370	COG1546	Belongs to the CinA family
I9X38_12375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
I9X38_12380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I9X38_12385	COG1418	mRNA catabolic process
I9X38_12390	COG1692	metallophosphoesterase
I9X38_12395	COG2359	stage V sporulation protein S
I9X38_12400	COG1063	alcohol dehydrogenase
I9X38_12405	COG0156	8-amino-7-oxononanoate synthase activity
I9X38_12410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I9X38_12415	COG4550	Control of competence regulator ComK, YlbF/YmcA
I9X38_12425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
I9X38_12430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
I9X38_12495	COG3226	Transcriptional regulator
I9X38_12500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_12505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I9X38_12510	COG3321	synthase
I9X38_12515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I9X38_12515	COG2070	2-Nitropropane dioxygenase
I9X38_12520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_12525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I9X38_12530	COG3425	synthase
I9X38_12535	COG1024	Enoyl-CoA hydratase
I9X38_12540	COG1024	Enoyl-CoA hydratase
I9X38_12545	COG0300	oxidoreductase activity
I9X38_12545	COG3321	synthase
I9X38_12545	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_12545	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_12545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_12550	COG3321	synthase
I9X38_12550	COG4221	oxidoreductase activity
I9X38_12550	COG0300	oxidoreductase activity
I9X38_12550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_12555	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_12555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_12555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_12555	COG3321	synthase
I9X38_12555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_12565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_12570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
I9X38_12575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
I9X38_12595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_12600	COG1725	Transcriptional regulator
I9X38_12625	COG2732	(Barnase) inhibitor
I9X38_12630	COG0454	-acetyltransferase
I9X38_12635	COG2311	Membrane
I9X38_12640	COG0745	RESPONSE REGULATOR receiver
I9X38_12645	COG0642	Histidine kinase
I9X38_12645	COG5002	protein histidine kinase activity
I9X38_12650	COG3223	Belongs to the PsiE family
I9X38_12665	COG3209	COG3209 Rhs family protein
I9X38_12675	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
I9X38_12680	COG0398	Pfam SNARE associated Golgi protein
I9X38_12685	COG5632	N-Acetylmuramoyl-L-alanine amidase
I9X38_12685	COG3409	Peptidoglycan-binding domain 1 protein
I9X38_12690	COG2755	lipolytic protein G-D-S-L family
I9X38_12705	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
I9X38_12710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I9X38_12715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
I9X38_12720	COG1534	Rna-binding protein
I9X38_12725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
I9X38_12730	COG1713	HD superfamily hydrolase involved in NAD metabolism
I9X38_12735	COG0799	negative regulation of ribosome biogenesis
I9X38_12740	COG2226	methyltransferase
I9X38_12745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I9X38_12750	COG1555	photosystem II stabilization
I9X38_12750	COG1596	polysaccharide export
I9X38_12755	COG2131	deaminase
I9X38_12760	COG0658	competence protein
I9X38_12760	COG2333	competence protein COMEC
I9X38_12775	COG1466	dna polymerase III delta subunit
I9X38_12785	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I9X38_12790	COG0860	N-Acetylmuramoyl-L-alanine amidase
I9X38_12800	COG0481	GTPase activity
I9X38_12805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I9X38_12810	COG1420	regulation of RNA biosynthetic process
I9X38_12815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
I9X38_12825	COG0484	heat shock protein binding
I9X38_12830	COG2264	protein methyltransferase activity
I9X38_12835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I9X38_12840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
I9X38_12845	COG1283	sodium-dependent phosphate transmembrane transporter activity
I9X38_12855	COG1610	YqeY-like protein
I9X38_12860	COG1030	water channel activity
I9X38_12865	COG4864	UPF0365 protein
I9X38_12880	COG0561	phosphatase activity
I9X38_12885	COG1702	phosphate starvation-inducible protein PhoH
I9X38_12890	COG1480	7TM receptor with intracellular HD hydrolase
I9X38_12895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
I9X38_12900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I9X38_12905	COG0295	cytidine deaminase activity
I9X38_12910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
I9X38_12920	COG1381	Involved in DNA repair and RecF pathway recombination
I9X38_12925	COG0752	glycyl-tRNA synthetase alpha subunit
I9X38_12930	COG0751	glycine-tRNA ligase activity
I9X38_12935	COG0517	IMP dehydrogenase activity
I9X38_12940	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
I9X38_12945	COG1671	Belongs to the UPF0178 family
I9X38_12950	COG0358	DNA primase activity
I9X38_12955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I9X38_12960	COG2010	Cytochrome c
I9X38_12965	COG2384	SAM-dependent methyltransferase
I9X38_12970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
I9X38_12975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
I9X38_12985	COG0513	Belongs to the DEAD box helicase family
I9X38_12990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
I9X38_13000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_13005	COG0735	belongs to the Fur family
I9X38_13010	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
I9X38_13015	COG4709	membrane
I9X38_13020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
I9X38_13025	COG1388	LysM domain
I9X38_13030	COG5521	maltodextrose utilization protein MalA
I9X38_13035	COG2839	Protein conserved in bacteria
I9X38_13040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I9X38_13045	COG0477	Major facilitator Superfamily
I9X38_13050	COG0768	penicillin binding
I9X38_13055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I9X38_13060	COG0573	inorganic phosphate transmembrane transporter activity
I9X38_13065	COG0581	inorganic phosphate transmembrane transporter activity
I9X38_13070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I9X38_13075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
I9X38_13080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I9X38_13095	COG0438	transferase activity, transferring glycosyl groups
I9X38_13105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I9X38_13115	COG0457	Tetratricopeptide repeat
I9X38_13115	COG0705	Rhomboid family
I9X38_13120	COG4483	Protein conserved in bacteria
I9X38_13125	COG1940	carbohydrate kinase activity
I9X38_13130	COG1368	sulfuric ester hydrolase activity
I9X38_13135	COG2866	Carboxypeptidase
I9X38_13145	COG0011	TIGRFAM Protein of
I9X38_13155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_13165	COG1393	Belongs to the ArsC family
I9X38_13175	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_13180	COG1253	flavin adenine dinucleotide binding
I9X38_13185	COG0598	Magnesium transport protein CorA
I9X38_13190	COG0517	IMP dehydrogenase activity
I9X38_13195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I9X38_13200	COG1459	type II secretion system
I9X38_13205	COG4537	Required for transformation and DNA binding
I9X38_13210	COG4970	Tfp pilus assembly protein FimT
I9X38_13220	COG4940	Competence protein ComGF
I9X38_13245	COG0681	Belongs to the peptidase S26 family
I9X38_13255	COG1396	sequence-specific DNA binding
I9X38_13270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I9X38_13275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
I9X38_13280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I9X38_13285	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I9X38_13290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I9X38_13295	COG0095	Lipoate-protein ligase
I9X38_13300	COG1321	iron dependent repressor
I9X38_13305	COG1752	Esterase of the alpha-beta hydrolase superfamily
I9X38_13315	COG3872	metal-dependent enzyme
I9X38_13325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
I9X38_13330	COG0006	proline dipeptidase activity
I9X38_13335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
I9X38_13345	COG3854	ATPases associated with a variety of cellular activities
I9X38_13385	COG0511	ligase activity, forming carbon-carbon bonds
I9X38_13390	COG0439	Biotin carboxylase
I9X38_13395	COG1302	Protein conserved in bacteria
I9X38_13400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I9X38_13405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
I9X38_13410	COG1570	exodeoxyribonuclease VII activity
I9X38_13415	COG1722	exodeoxyribonuclease VII activity
I9X38_13420	COG0142	geranyltranstransferase activity
I9X38_13425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
I9X38_13430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
I9X38_13435	COG1438	arginine binding
I9X38_13440	COG0497	DNA recombination
I9X38_13445	COG0750	zinc metalloprotease
I9X38_13450	COG0745	RESPONSE REGULATOR receiver
I9X38_13455	COG1902	pentaerythritol trinitrate reductase activity
I9X38_13470	COG0860	N-Acetylmuramoyl-L-alanine amidase
I9X38_13475	COG0584	glycerophosphoryl diester phosphodiesterase
I9X38_13480	COG0183	Belongs to the thiolase family
I9X38_13485	COG1250	3-hydroxyacyl-CoA dehydrogenase
I9X38_13490	COG1960	acyl-CoA dehydrogenase activity
I9X38_13495	COG0372	Belongs to the citrate synthase family
I9X38_13500	COG2079	MmgE PrpD family protein
I9X38_13505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
I9X38_13515	COG3829	transcription factor binding
I9X38_13515	COG3290	protein histidine kinase activity
I9X38_13520	COG0280	phosphate acetyltransferase
I9X38_13525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I9X38_13530	COG3426	butyrate kinase activity
I9X38_13535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I9X38_13540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I9X38_13545	COG0022	dehydrogenase e1 component
I9X38_13550	COG0508	dehydrogenase complex catalyzes the overall conversion of
I9X38_13555	COG4978	Transcriptional regulator
I9X38_13555	COG0789	Transcriptional regulator
I9X38_13560	COG2814	Major facilitator Superfamily
I9X38_13565	COG1597	lipid kinase activity
I9X38_13575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I9X38_13580	COG0765	amino acid transport
I9X38_13585	COG1126	abc transporter atp-binding protein
I9X38_13590	COG4129	membrane
I9X38_13595	COG1376	ErfK ybiS ycfS ynhG family protein
I9X38_13605	COG0346	lactoylglutathione lyase activity
I9X38_13610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I9X38_13615	COG2195	Cleaves the N-terminal amino acid of tripeptides
I9X38_13620	COG3361	conserved protein (COG2071)
I9X38_13625	COG0706	membrane insertase activity
I9X38_13635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I9X38_13640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
I9X38_13650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I9X38_13655	COG1234	tRNA 3'-trailer cleavage
I9X38_13665	COG0596	Alpha beta hydrolase
I9X38_13670	COG1902	pentaerythritol trinitrate reductase activity
I9X38_13675	COG4187	Peptidase family M20/M25/M40
I9X38_13680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I9X38_13685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_13690	COG0300	oxidoreductase activity
I9X38_13695	COG3048	D-serine ammonia-lyase activity
I9X38_13700	COG1072	(Pantothenic acid kinase))
I9X38_13705	COG0346	lactoylglutathione lyase activity
I9X38_13725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I9X38_13735	COG0456	acetyltransferase
I9X38_13740	COG2329	Antibiotic biosynthesis monooxygenase
I9X38_13745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
I9X38_13745	COG0456	acetyltransferase
I9X38_13750	COG4918	Iron-sulphur cluster biosynthesis
I9X38_13760	COG1073	alpha beta
I9X38_13770	COG0667	Aldo Keto reductase
I9X38_13780	COG0494	nUDIX hydrolase
I9X38_13785	COG1379	DNA repair
I9X38_13790	COG1396	sequence-specific DNA binding
I9X38_13795	COG0252	asparaginase activity
I9X38_13800	COG1027	Aspartate ammonia-lyase
I9X38_13805	COG1757	Na H antiporter
I9X38_13810	COG0281	malic enzyme
I9X38_13820	COG1300	Membrane
I9X38_13825	COG0735	belongs to the Fur family
I9X38_13835	COG4974	Belongs to the 'phage' integrase family
I9X38_13840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
I9X38_13845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
I9X38_13850	COG1686	Belongs to the peptidase S11 family
I9X38_13855	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_13860	COG2172	sigma factor antagonist activity
I9X38_13865	COG1191	sigma factor activity
I9X38_13885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I9X38_13900	COG0697	spore germination
I9X38_13905	COG0019	diaminopimelate decarboxylase activity
I9X38_13910	COG4086	secreted protein
I9X38_13915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I9X38_13920	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
I9X38_13925	COG0681	Belongs to the peptidase S26 family
I9X38_13935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I9X38_13935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I9X38_13940	COG0307	riboflavin synthase, alpha
I9X38_13945	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
I9X38_13945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
I9X38_13950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
I9X38_13955	COG0456	acetyltransferase
I9X38_13960	COG1547	Domain of unknown function (DUF309)
I9X38_13970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
I9X38_13975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I9X38_13985	COG1686	Belongs to the peptidase S11 family
I9X38_13990	COG2715	membrane protein required for spore maturation
I9X38_13995	COG0700	Nucleoside recognition
I9X38_14000	COG1187	pseudouridine synthase activity
I9X38_14005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_14010	COG1333	cytochrome c biogenesis protein
I9X38_14015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I9X38_14020	COG0745	RESPONSE REGULATOR receiver
I9X38_14025	COG5002	protein histidine kinase activity
I9X38_14030	COG1595	DNA-templated transcription, initiation
I9X38_14040	COG0710	3-dehydroquinate dehydratase activity
I9X38_14045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I9X38_14050	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
I9X38_14055	COG1141	Ferredoxin
I9X38_14060	COG4955	Helix-turn-helix domain
I9X38_14065	COG0514	ATP-dependent DNA helicase (RecQ)
I9X38_14070	COG1266	CAAX protease self-immunity
I9X38_14075	COG1388	LysM domain
I9X38_14085	COG1408	metallophosphoesterase
I9X38_14090	COG4862	establishment of competence for transformation
I9X38_14095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I9X38_14100	COG0492	ferredoxin-NADP+ reductase activity
I9X38_14105	COG2339	peptidase activity
I9X38_14110	COG3409	Peptidoglycan-binding domain 1 protein
I9X38_14110	COG3773	Cell wall hydrolase
I9X38_14115	COG2959	enzyme of heme biosynthesis
I9X38_14120	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
I9X38_14130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
I9X38_14135	COG0539	negative regulation of cytoplasmic translation
I9X38_14140	COG1304	FMN binding
I9X38_14165	COG1160	GTP binding
I9X38_14170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
I9X38_14185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I9X38_14190	COG0776	regulation of translation
I9X38_14195	COG0302	gtp cyclohydrolase
I9X38_14205	COG0142	geranyltranstransferase activity
I9X38_14210	COG2226	methyltransferase
I9X38_14215	COG0142	geranyltranstransferase activity
I9X38_14220	COG0105	UTP biosynthetic process
I9X38_14225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
I9X38_14230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
I9X38_14235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
I9X38_14240	COG4401	Chorismate mutase type I
I9X38_14245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I9X38_14250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I9X38_14260	COG0135	phosphoribosylanthranilate isomerase activity
I9X38_14265	COG0133	tryptophan synthase activity
I9X38_14270	COG0159	tryptophan synthase activity
I9X38_14275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I9X38_14280	COG0287	Prephenate dehydrogenase
I9X38_14285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I9X38_14290	COG0457	Tetratricopeptide repeat
I9X38_14295	COG5582	Belongs to the UPF0302 family
I9X38_14305	COG0723	plastoquinol--plastocyanin reductase activity
I9X38_14310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I9X38_14315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
I9X38_14315	COG2010	Cytochrome c
I9X38_14320	COG4347	Protein of unknown function (DUF1405)
I9X38_14330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_14335	COG1694	Mazg nucleotide pyrophosphohydrolase
I9X38_14340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
I9X38_14345	COG1803	Methylglyoxal synthase
I9X38_14350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I9X38_14355	COG0438	transferase activity, transferring glycosyl groups
I9X38_14360	COG0617	tRNA 3'-terminal CCA addition
I9X38_14365	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
I9X38_14365	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
I9X38_14370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
I9X38_14375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
I9X38_14380	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
I9X38_14385	COG1199	ATP-dependent helicase activity
I9X38_14385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I9X38_14395	COG5353	protein conserved in bacteria
I9X38_14400	COG0436	Aminotransferase
I9X38_14405	COG0017	Asparaginyl-tRNA synthetase
I9X38_14410	COG3935	DnaD domain protein
I9X38_14415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I9X38_14425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I9X38_14425	COG4499	WXG100 protein secretion system (Wss), protein YukC
I9X38_14430	COG3331	DNA recombination
I9X38_14465	COG0071	Belongs to the small heat shock protein (HSP20) family
I9X38_14470	COG2190	(PTS) system
I9X38_14475	COG1205	dead DEAH box helicase
I9X38_14475	COG1111	helicase
I9X38_14480	COG3359	exonuclease
I9X38_14495	COG4474	Belongs to the UPF0398 family
I9X38_14510	COG0116	Belongs to the methyltransferase superfamily
I9X38_14525	COG1199	ATP-dependent helicase activity
I9X38_14530	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_14535	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
I9X38_14540	COG1609	Transcriptional regulator
I9X38_14545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I9X38_14550	COG0800	Aldolase
I9X38_14560	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
I9X38_14565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I9X38_14570	COG2233	PERMEase
I9X38_14575	COG3424	synthase
I9X38_14580	COG1755	Isoprenylcysteine carboxyl methyltransferase
I9X38_14590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
I9X38_14605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I9X38_14615	COG0328	RNA-DNA hybrid ribonuclease activity
I9X38_14620	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I9X38_14625	COG0328	RNA-DNA hybrid ribonuclease activity
I9X38_14645	COG1278	Cold shock
I9X38_14655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
I9X38_14660	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
I9X38_14665	COG0386	Belongs to the glutathione peroxidase family
I9X38_14670	COG1418	mRNA catabolic process
I9X38_14675	COG1413	lyase activity
I9X38_14680	COG0129	dihydroxy-acid dehydratase activity
I9X38_14690	COG2521	methyltransferase
I9X38_14690	COG2136	Putative SAM-dependent methyltransferase
I9X38_14700	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I9X38_14710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I9X38_14715	COG0204	Acyl-transferase
I9X38_14720	COG1272	protein, Hemolysin III
I9X38_14725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I9X38_14730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I9X38_14740	COG1999	signal sequence binding
I9X38_14745	COG2755	lipolytic protein G-D-S-L family
I9X38_14750	COG4698	Protein conserved in bacteria
I9X38_14760	COG0534	Mate efflux family protein
I9X38_14765	COG1846	Transcriptional regulator
I9X38_14770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I9X38_14780	COG1086	Polysaccharide biosynthesis protein
I9X38_14785	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
I9X38_14790	COG4641	Protein conserved in bacteria
I9X38_14805	COG0463	Glycosyl transferase, family 2
I9X38_14810	COG0456	acetyltransferase
I9X38_14820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I9X38_14825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I9X38_14830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I9X38_14835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
I9X38_14840	COG0456	acetyltransferase
I9X38_14845	COG1509	lysine 2,3-aminomutase activity
I9X38_14855	COG4479	Belongs to the UPF0346 family
I9X38_14875	COG0671	phosphoesterase, PA-phosphatase related
I9X38_14890	COG0813	purine-nucleoside phosphorylase activity
I9X38_14895	COG1876	peptidase activity
I9X38_14905	COG2226	methyltransferase
I9X38_14910	COG0793	Belongs to the peptidase S41A family
I9X38_14910	COG3409	Peptidoglycan-binding domain 1 protein
I9X38_14915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I9X38_14925	COG0346	lactoylglutathione lyase activity
I9X38_14930	COG0400	carboxylic ester hydrolase activity
I9X38_14935	COG0778	Nitroreductase
I9X38_14940	COG1733	regulation of RNA biosynthetic process
I9X38_14950	COG1942	4-Oxalocrotonate Tautomerase
I9X38_14970	COG2962	Rard protein
I9X38_14980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I9X38_14985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
I9X38_14990	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_14995	COG0534	Mate efflux family protein
I9X38_15000	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
I9X38_15005	COG1819	glycosyl
I9X38_15010	COG1388	LysM domain
I9X38_15010	COG0791	NLP P60 protein
I9X38_15015	COG2032	superoxide dismutase activity
I9X38_15020	COG0714	Associated with various cellular activities
I9X38_15025	COG4548	von Willebrand factor, type A
I9X38_15030	COG0567	Dehydrogenase, E1 component
I9X38_15035	COG0508	dehydrogenase complex catalyzes the overall conversion of
I9X38_15040	COG0385	Bile acid
I9X38_15045	COG0733	neurotransmitter:sodium symporter activity
I9X38_15050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I9X38_15055	COG1657	PFAM Prenyltransferase squalene oxidase
I9X38_15060	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_15075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I9X38_15080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
I9X38_15090	COG0514	ATP-dependent DNA helicase (RecQ)
I9X38_15095	COG3584	3D domain protein
I9X38_15095	COG1388	LysM domain
I9X38_15105	COG2197	response regulator
I9X38_15110	COG4585	Histidine kinase
I9X38_15115	COG3239	Fatty acid desaturase
I9X38_15120	COG1619	proteins homologs of microcin C7 resistance protein MccF
I9X38_15135	COG2322	membrane
I9X38_15140	COG0741	lytic transglycosylase activity
I9X38_15145	COG0640	Transcriptional regulator
I9X38_15155	COG2378	regulation of single-species biofilm formation
I9X38_15160	COG3708	Transcriptional regulator
I9X38_15165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_15170	COG1309	transcriptional regulator
I9X38_15175	COG0456	acetyltransferase
I9X38_15180	COG2207	Transcriptional regulator
I9X38_15180	COG0662	Cupin 2, conserved barrel domain protein
I9X38_15185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I9X38_15190	COG1733	regulation of RNA biosynthetic process
I9X38_15195	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_15200	COG2801	Transposase and inactivated derivatives
I9X38_15240	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_15250	COG3619	membrane
I9X38_15255	COG4305	rare lipoprotein A
I9X38_15265	COG0243	molybdopterin cofactor binding
I9X38_15270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I9X38_15275	COG1070	Carbohydrate kinase
I9X38_15280	COG2814	Major facilitator Superfamily
I9X38_15290	COG1131	(ABC) transporter
I9X38_15305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_15315	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
I9X38_15320	COG0300	oxidoreductase activity
I9X38_15340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I9X38_15345	COG0583	DNA-binding transcription factor activity
I9X38_15350	COG0070	glutamate synthase
I9X38_15350	COG0067	glutamate synthase
I9X38_15350	COG0069	glutamate synthase activity
I9X38_15355	COG0493	'glutamate synthase
I9X38_15360	COG0604	alcohol dehydrogenase
I9X38_15365	COG0583	DNA-binding transcription factor activity
I9X38_15370	COG0405	Gamma-glutamyltransferase
I9X38_15375	COG0166	Belongs to the GPI family
I9X38_15380	COG0582	viral genome integration into host DNA
I9X38_15395	COG0534	Mate efflux family protein
I9X38_15400	COG2017	converts alpha-aldose to the beta-anomer
I9X38_15405	COG2027	D-alanyl-D-alanine carboxypeptidase
I9X38_15430	COG2155	Conserved Protein
I9X38_15435	COG1979	alcohol dehydrogenase
I9X38_15440	COG1979	alcohol dehydrogenase
I9X38_15445	COG0166	Belongs to the GPI family
I9X38_15460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I9X38_15475	COG2738	Putative neutral zinc metallopeptidase
I9X38_15480	COG1253	flavin adenine dinucleotide binding
I9X38_15485	COG0366	Alpha amylase catalytic
I9X38_15490	COG0432	Pfam Uncharacterised protein family UPF0047
I9X38_15495	COG2070	2-Nitropropane dioxygenase
I9X38_15510	COG0840	transmembrane signaling receptor activity
I9X38_15515	COG0840	transmembrane signaling receptor activity
I9X38_15520	COG0840	transmembrane signaling receptor activity
I9X38_15525	COG0840	transmembrane signaling receptor activity
I9X38_15530	COG3347	Dehydrogenase
I9X38_15530	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_15535	COG1349	DNA-binding transcription factor activity
I9X38_15540	COG1070	Carbohydrate kinase
I9X38_15545	COG3254	rhamnose metabolic process
I9X38_15550	COG4806	L-rhamnose isomerase
I9X38_15555	COG0673	inositol 2-dehydrogenase activity
I9X38_15560	COG0628	permease
I9X38_15565	COG1968	undecaprenyl-diphosphatase activity
I9X38_15575	COG5553	Cysteine dioxygenase type I
I9X38_15580	COG0477	Major facilitator Superfamily
I9X38_15585	COG1705	Flagellar rod assembly protein muramidase FlgJ
I9X38_15590	COG4682	membrane
I9X38_15595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I9X38_15600	COG0569	domain protein
I9X38_15610	COG1510	regulation of RNA biosynthetic process
I9X38_15615	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_15620	COG1454	alcohol dehydrogenase
I9X38_15630	COG2318	DinB family
I9X38_15635	COG1585	Membrane protein implicated in regulation of membrane protease activity
I9X38_15640	COG2268	Band 7 protein
I9X38_15645	COG1247	-acetyltransferase
I9X38_15650	COG3859	Proton-coupled thiamine transporter YuaJ
I9X38_15660	COG5566	PFAM Mor transcription activator
I9X38_15665	COG0596	Alpha beta hydrolase
I9X38_15670	COG0697	spore germination
I9X38_15680	COG4991	sh3 domain protein
I9X38_15685	COG4991	sh3 domain protein
I9X38_15710	COG0693	protein deglycase activity
I9X38_15715	COG1621	beta-fructofuranosidase activity
I9X38_15720	COG3716	PTS system mannose fructose sorbose family IID component
I9X38_15725	COG3715	PTS system
I9X38_15730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_15735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_15740	COG3933	PFAM sigma-54 factor interaction domain-containing protein
I9X38_15740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I9X38_15745	COG1113	amino acid transport
I9X38_15750	COG1280	lysine exporter protein (LysE YggA)
I9X38_15755	COG1378	Sugar-specific transcriptional regulator TrmB
I9X38_15760	COG1595	DNA-templated transcription, initiation
I9X38_15770	COG2755	lipolytic protein G-D-S-L family
I9X38_15770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
I9X38_15780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I9X38_15780	COG2124	cytochrome p450
I9X38_15785	COG1309	transcriptional regulator
I9X38_15790	COG2226	methyltransferase
I9X38_15805	COG2116	formate transmembrane transporter activity
I9X38_15810	COG5609	conserved protein (DUF2294)
I9X38_15815	COG3383	formate dehydrogenase (NAD+) activity
I9X38_15820	COG2427	Protein of unknown function (DUF1641)
I9X38_15830	COG0626	cystathionine gamma-synthase activity
I9X38_15835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
I9X38_15840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I9X38_15845	COG2226	methyltransferase
I9X38_15860	COG0768	penicillin binding
I9X38_15865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I9X38_15870	COG0572	uridine kinase
I9X38_15875	COG0826	peptidase U32
I9X38_15880	COG0826	peptidase U32
I9X38_15885	COG4122	O-methyltransferase activity
I9X38_15890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I9X38_15895	COG3906	Belongs to the UPF0473 family
I9X38_15900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
I9X38_15905	COG4472	Bacterial protein of unknown function (DUF965)
I9X38_15910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
I9X38_15915	COG0628	permease
I9X38_15920	COG1126	abc transporter atp-binding protein
I9X38_15925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I9X38_15930	COG0765	amino acid transport
I9X38_15935	COG0765	amino acid transport
I9X38_15950	COG3881	PFAM PRC-barrel domain
I9X38_15955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I9X38_15960	COG0457	Tetratricopeptide repeat
I9X38_15965	COG0482	sulfurtransferase activity
I9X38_15970	COG1104	cysteine desulfurase activity
I9X38_15975	COG1959	2 iron, 2 sulfur cluster binding
I9X38_15980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I9X38_15985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I9X38_15995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
I9X38_16000	COG0124	histidyl-tRNA synthetase
I9X38_16010	COG0860	N-Acetylmuramoyl-L-alanine amidase
I9X38_16010	COG3103	Sh3 type 3 domain protein
I9X38_16010	COG4991	sh3 domain protein
I9X38_16015	COG1490	D-aminoacyl-tRNA deacylase activity
I9X38_16020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I9X38_16025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I9X38_16030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
I9X38_16030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I9X38_16035	COG5416	Lipopolysaccharide assembly protein A domain
I9X38_16040	COG0490	domain, Protein
I9X38_16045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I9X38_16045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I9X38_16055	COG2244	polysaccharide biosynthetic process
I9X38_16060	COG2323	membrane
I9X38_16070	COG1862	Preprotein translocase
I9X38_16075	COG0343	queuine tRNA-ribosyltransferase activity
I9X38_16080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I9X38_16090	COG2255	four-way junction helicase activity
I9X38_16095	COG0632	four-way junction helicase activity
I9X38_16105	COG2814	Major facilitator Superfamily
I9X38_16110	COG0673	inositol 2-dehydrogenase activity
I9X38_16115	COG2112	serine threonine protein kinase
I9X38_16130	COG1115	amino acid carrier protein
I9X38_16135	COG0217	transcriptional regulatory protein
I9X38_16145	COG1388	LysM domain
I9X38_16150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
I9X38_16155	COG0157	Belongs to the NadC ModD family
I9X38_16160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
I9X38_16165	COG1104	cysteine desulfurase activity
I9X38_16170	COG1827	regulation of RNA biosynthetic process
I9X38_16175	COG0077	Prephenate dehydratase
I9X38_16180	COG4492	Belongs to the UPF0735 family
I9X38_16185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
I9X38_16190	COG3290	protein histidine kinase activity
I9X38_16200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
I9X38_16205	COG2868	ribosomal protein
I9X38_16210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
I9X38_16215	COG1994	Peptidase M50
I9X38_16220	COG0739	heme binding
I9X38_16225	COG2894	cell division
I9X38_16230	COG0850	regulation of cytokinetic process
I9X38_16235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I9X38_16245	COG1077	Cell shape determining protein MreB Mrl
I9X38_16250	COG2003	Belongs to the UPF0758 family
I9X38_16255	COG0424	maF-like protein
I9X38_16265	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
I9X38_16270	COG0285	dihydrofolate synthase activity
I9X38_16275	COG0525	valine-tRNA ligase activity
I9X38_16285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
I9X38_16300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_16355	COG2814	Major facilitator Superfamily
I9X38_16360	COG1525	nuclease
I9X38_16365	COG1231	oxidoreductase activity
I9X38_16370	COG1070	Carbohydrate kinase
I9X38_16385	COG3507	Belongs to the glycosyl hydrolase 43 family
I9X38_16390	COG2211	Major facilitator Superfamily
I9X38_16405	COG3397	chitin binding
I9X38_16410	COG2318	DinB family
I9X38_16415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_16455	COG0457	Tetratricopeptide repeat
I9X38_16485	COG0735	belongs to the Fur family
I9X38_16490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I9X38_16495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
I9X38_16500	COG4129	membrane
I9X38_16505	COG1132	(ABC) transporter
I9X38_16510	COG3557	Belongs to the UPF0374 family
I9X38_16525	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_16535	COG1194	a g-specific adenine glycosylase
I9X38_16540	COG1988	membrane-bound metal-dependent
I9X38_16545	COG4485	Bacterial membrane protein, YfhO
I9X38_16550	COG0463	Glycosyl transferase, family 2
I9X38_16555	COG0596	Alpha beta hydrolase
I9X38_16560	COG5658	integral membrane protein
I9X38_16565	COG3103	Sh3 type 3 domain protein
I9X38_16570	COG1476	TRANSCRIPTIONal
I9X38_16590	COG2814	Major facilitator Superfamily
I9X38_16600	COG2137	regulation of response to DNA damage stimulus
I9X38_16605	COG1090	epimerase
I9X38_16620	COG0778	Nitroreductase
I9X38_16625	COG0384	phenazine biosynthesis protein PhzF
I9X38_16630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_16635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_16640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I9X38_16645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
I9X38_16645	COG0392	lysyltransferase activity
I9X38_16650	COG1846	Transcriptional regulator
I9X38_16655	COG2814	Major facilitator Superfamily
I9X38_16660	COG2318	DinB family
I9X38_16665	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
I9X38_16670	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
I9X38_16675	COG1695	Transcriptional regulator
I9X38_16685	COG0842	Transport permease protein
I9X38_16690	COG1511	domain protein
I9X38_16690	COG0842	Transport permease protein
I9X38_16695	COG1131	(ABC) transporter
I9X38_16700	COG2197	response regulator
I9X38_16705	COG4585	Histidine kinase
I9X38_16710	COG2514	catechol 2,3-dioxygenase activity
I9X38_16715	COG2259	Doxx family
I9X38_16720	COG1132	(ABC) transporter
I9X38_16725	COG1132	(ABC) transporter
I9X38_16730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_16730	COG1263	PTS System
I9X38_16735	COG1737	Transcriptional regulator
I9X38_16740	COG1486	melibiose metabolic process
I9X38_16745	COG4842	Belongs to the WXG100 family
I9X38_16765	COG1742	UPF0060 membrane protein
I9X38_16775	COG3284	Transcriptional regulator
I9X38_16780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I9X38_16785	COG0508	dehydrogenase complex catalyzes the overall conversion of
I9X38_16790	COG0022	dehydrogenase e1 component
I9X38_16795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I9X38_16805	COG4637	Psort location Cytoplasmic, score
I9X38_16815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I9X38_16820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
I9X38_16825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I9X38_16830	COG0598	Magnesium transport protein CorA
I9X38_16835	COG2084	Dehydrogenase
I9X38_16840	COG0726	polysaccharide deacetylase
I9X38_16850	COG0535	radical SAM domain protein
I9X38_16855	COG0668	transmembrane transport
I9X38_16865	COG0387	Pfam Sodium calcium exchanger
I9X38_16870	COG0477	Major facilitator Superfamily
I9X38_16875	COG1295	ribonuclease BN
I9X38_16880	COG4980	gas vesicle protein
I9X38_16885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I9X38_16890	COG4840	Belongs to the UPF0435 family
I9X38_16895	COG2814	Major facilitator Superfamily
I9X38_16900	COG0693	protein deglycase activity
I9X38_16905	COG0737	Belongs to the 5'-nucleotidase family
I9X38_16910	COG0778	Nitroreductase
I9X38_16915	COG2188	Transcriptional regulator
I9X38_16920	COG0366	Alpha amylase catalytic
I9X38_16925	COG1263	PTS System
I9X38_16925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_16940	COG1368	sulfuric ester hydrolase activity
I9X38_16945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I9X38_16945	COG1263	PTS System
I9X38_16950	COG0024	Methionine aminopeptidase
I9X38_16970	COG2258	MOSC domain
I9X38_16975	COG1254	Belongs to the acylphosphatase family
I9X38_16980	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
I9X38_16985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I9X38_16990	COG2851	Citrate transporter
I9X38_16995	COG3181	Tripartite tricarboxylate transporter family receptor
I9X38_17000	COG4565	transcriptional regulatory protein
I9X38_17005	COG3290	protein histidine kinase activity
I9X38_17015	COG0471	metal ion transport
I9X38_17020	COG3866	Pectate lyase
I9X38_17035	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
I9X38_17040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_17045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_17050	COG1120	ATPase activity
I9X38_17055	COG2130	NADP-dependent
I9X38_17060	COG0456	acetyltransferase
I9X38_17065	COG0513	Belongs to the DEAD box helicase family
I9X38_17070	COG0488	(ABC) transporter
I9X38_17080	COG2814	Major facilitator Superfamily
I9X38_17085	COG0789	Transcriptional regulator
I9X38_17095	COG0488	(ABC) transporter
I9X38_17100	COG0840	transmembrane signaling receptor activity
I9X38_17105	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_17110	COG0531	amino acid
I9X38_17115	COG1011	Hydrolase
I9X38_17120	COG2223	nitrite transmembrane transporter activity
I9X38_17125	COG1442	glycosyl transferase family 8
I9X38_17130	COG1216	Glycosyl transferase, family 2
I9X38_17135	COG1442	glycosyl transferase family 8
I9X38_17140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_17145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
I9X38_17150	COG1368	sulfuric ester hydrolase activity
I9X38_17155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
I9X38_17155	COG2124	cytochrome p450
I9X38_17165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I9X38_17170	COG1846	Transcriptional regulator
I9X38_17175	COG0670	Belongs to the BI1 family
I9X38_17180	COG5583	Uncharacterized small protein (DUF2292)
I9X38_17185	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_17195	COG0346	lactoylglutathione lyase activity
I9X38_17200	COG2329	Antibiotic biosynthesis monooxygenase
I9X38_17205	COG2323	membrane
I9X38_17210	COG1486	melibiose metabolic process
I9X38_17215	COG0395	ABC-type sugar transport system, permease component
I9X38_17220	COG4209	transmembrane transport
I9X38_17225	COG1653	transport
I9X38_17235	COG1874	Beta-galactosidase
I9X38_17240	COG2755	lipolytic protein G-D-S-L family
I9X38_17245	COG0667	Aldo Keto reductase
I9X38_17250	COG3401	FG-GAP repeat protein
I9X38_17255	COG3401	FG-GAP repeat protein
I9X38_17260	COG5578	integral membrane protein
I9X38_17270	COG2755	lipolytic protein G-D-S-L family
I9X38_17275	COG2207	Transcriptional regulator
I9X38_17280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
I9X38_17285	COG0395	ABC-type sugar transport system, permease component
I9X38_17290	COG1175	transmembrane transport
I9X38_17295	COG1653	transport
I9X38_17300	COG2207	Transcriptional regulator
I9X38_17300	COG4753	response regulator
I9X38_17305	COG2972	Histidine kinase
I9X38_17310	COG5578	integral membrane protein
I9X38_17320	COG0454	-acetyltransferase
I9X38_17325	COG3546	catalase activity
I9X38_17345	COG0702	epimerase
I9X38_17350	COG3631	Ketosteroid isomerase-related protein
I9X38_17355	COG1309	transcriptional regulator
I9X38_17365	COG0217	transcriptional regulatory protein
I9X38_17375	COG0457	Tetratricopeptide repeat
I9X38_17380	COG3391	amine dehydrogenase activity
I9X38_17390	COG3425	synthase
I9X38_17395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I9X38_17395	COG2070	2-Nitropropane dioxygenase
I9X38_17400	COG0300	oxidoreductase activity
I9X38_17400	COG4221	oxidoreductase activity
I9X38_17400	COG3321	synthase
I9X38_17400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_17405	COG3321	synthase
I9X38_17405	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_17405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_17405	COG4221	oxidoreductase activity
I9X38_17410	COG0300	oxidoreductase activity
I9X38_17410	COG3321	synthase
I9X38_17410	COG4221	oxidoreductase activity
I9X38_17410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_17430	COG0517	IMP dehydrogenase activity
I9X38_17430	COG0516	GMP reductase activity
I9X38_17435	COG1686	Belongs to the peptidase S11 family
I9X38_17445	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
I9X38_17450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
I9X38_17460	COG1428	Deoxynucleoside kinase
I9X38_17465	COG1428	Deoxynucleoside kinase
I9X38_17470	COG1388	LysM domain
I9X38_17470	COG3858	chitin binding
I9X38_17475	COG1335	isochorismatase
I9X38_17480	COG0590	tRNA wobble adenosine to inosine editing
I9X38_17490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I9X38_17495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
I9X38_17500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
I9X38_17515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
I9X38_17525	COG1329	Transcriptional regulator
I9X38_17530	COG0346	lactoylglutathione lyase activity
I9X38_17545	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
I9X38_17555	COG2364	Membrane
I9X38_17560	COG1846	Transcriptional regulator
I9X38_17565	COG0456	acetyltransferase
I9X38_17570	COG2808	Putative FMN-binding domain
I9X38_17585	COG0693	protein deglycase activity
I9X38_17590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_17595	COG4257	antibiotic catabolic process
I9X38_17600	COG0456	acetyltransferase
I9X38_17605	COG3711	transcriptional antiterminator
I9X38_17605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_17610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I9X38_17610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_17610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I9X38_17615	COG1482	cell wall glycoprotein biosynthetic process
I9X38_17620	COG2030	dehydratase
I9X38_17625	COG0697	spore germination
I9X38_17630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I9X38_17635	COG0596	Alpha beta hydrolase
I9X38_17640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_17645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I9X38_17650	COG1522	sequence-specific DNA binding
I9X38_17655	COG2323	membrane
I9X38_17660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_17665	COG1309	transcriptional regulator
I9X38_17675	COG0456	acetyltransferase
I9X38_17680	COG0488	(ABC) transporter
I9X38_17685	COG1113	amino acid transport
I9X38_17690	COG2318	DinB family
I9X38_17695	COG1846	Transcriptional regulator
I9X38_17700	COG2409	Drug exporters of the RND superfamily
I9X38_17700	COG1033	growth of symbiont in host cell
I9X38_17710	COG0778	Nitroreductase
I9X38_17715	COG1846	Transcriptional regulator
I9X38_17720	COG1396	sequence-specific DNA binding
I9X38_17725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I9X38_17735	COG2814	Major facilitator Superfamily
I9X38_17740	COG0730	response to heat
I9X38_17745	COG1802	Transcriptional regulator
I9X38_17750	COG1388	LysM domain
I9X38_17750	COG3858	chitin binding
I9X38_17755	COG1819	glycosyl
I9X38_17765	COG1785	Belongs to the alkaline phosphatase family
I9X38_17775	COG1078	dGTPase activity
I9X38_17780	COG1388	LysM domain
I9X38_17785	COG2814	Major facilitator Superfamily
I9X38_17790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I9X38_17795	COG1447	Phosphotransferase system cellobiose-specific component IIA
I9X38_17800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I9X38_17805	COG2723	6-phospho-beta-galactosidase activity
I9X38_17810	COG2188	Transcriptional regulator
I9X38_17815	COG1940	carbohydrate kinase activity
I9X38_17820	COG1482	cell wall glycoprotein biosynthetic process
I9X38_17825	COG4124	Belongs to the glycosyl hydrolase 26 family
I9X38_17845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_17850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_17855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
I9X38_17860	COG2814	Major facilitator Superfamily
I9X38_17870	COG0697	spore germination
I9X38_17875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I9X38_17885	COG2364	Membrane
I9X38_17890	COG1126	abc transporter atp-binding protein
I9X38_17895	COG0765	amino acid transport
I9X38_17900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I9X38_17905	COG0583	DNA-binding transcription factor activity
I9X38_17910	COG0163	prenyltransferase activity
I9X38_17915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
I9X38_17930	COG0596	Alpha beta hydrolase
I9X38_17935	COG3104	oligopeptide transport
I9X38_17940	COG5434	Belongs to the glycosyl hydrolase 28 family
I9X38_17950	COG0697	spore germination
I9X38_17960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
I9X38_17965	COG1136	(ABC) transporter
I9X38_17970	COG0577	efflux transmembrane transporter activity
I9X38_17975	COG0745	RESPONSE REGULATOR receiver
I9X38_17980	COG5002	protein histidine kinase activity
I9X38_17980	COG3850	Histidine kinase
I9X38_17985	COG0457	Tetratricopeptide repeat
I9X38_18005	COG0527	aspartate kinase activity
I9X38_18010	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I9X38_18015	COG4605	iron ion homeostasis
I9X38_18020	COG4604	ABC transporter, ATP-binding protein
I9X38_18025	COG4607	ABC-type enterochelin transport system periplasmic component
I9X38_18030	COG2814	Major facilitator Superfamily
I9X38_18035	COG1309	transcriptional regulator
I9X38_18040	COG0778	Nitroreductase
I9X38_18045	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I9X38_18050	COG0640	Transcriptional regulator
I9X38_18055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I9X38_18060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I9X38_18065	COG1012	belongs to the aldehyde dehydrogenase family
I9X38_18070	COG4975	Glucose uptake
I9X38_18075	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_18080	COG4549	nuclear export factor GLE1
I9X38_18085	COG2372	response to copper ion
I9X38_18085	COG1276	copper resistance
I9X38_18090	COG1349	DNA-binding transcription factor activity
I9X38_18100	COG2213	PTS system mannitol-specific
I9X38_18105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I9X38_18110	COG0246	Mannitol dehydrogenase
I9X38_18115	COG0473	3-isopropylmalate dehydrogenase activity
I9X38_18120	COG0412	Dienelactone hydrolase
I9X38_18125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
I9X38_18135	COG0561	phosphatase activity
I9X38_18140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
I9X38_18145	COG1914	H( )-stimulated, divalent metal cation uptake system
I9X38_18150	COG4336	lyase activity
I9X38_18155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I9X38_18160	COG1984	allophanate hydrolase subunit 2
I9X38_18165	COG1414	Transcriptional regulator
I9X38_18170	COG2755	lipolytic protein G-D-S-L family
I9X38_18180	COG2329	Antibiotic biosynthesis monooxygenase
I9X38_18185	COG0768	penicillin binding
I9X38_18190	COG4989	oxidoreductase activity
I9X38_18195	COG3711	transcriptional antiterminator
I9X38_18200	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_18205	COG2226	methyltransferase
I9X38_18210	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_18215	COG1917	Cupin 2, conserved barrel domain protein
I9X38_18220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_18225	COG3871	stress protein (general stress protein 26)
I9X38_18235	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I9X38_18240	COG2814	Major facilitator Superfamily
I9X38_18255	COG1522	sequence-specific DNA binding
I9X38_18260	COG0551	DNA topoisomerase type I activity
I9X38_18260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I9X38_18265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
I9X38_18270	COG3706	GGDEF domain
I9X38_18275	COG5298	Protein conserved in bacteria
I9X38_18280	COG1215	transferase activity, transferring glycosyl groups
I9X38_18290	COG0531	amino acid
I9X38_18295	COG0494	nUDIX hydrolase
I9X38_18300	COG0028	Belongs to the TPP enzyme family
I9X38_18310	COG1914	H( )-stimulated, divalent metal cation uptake system
I9X38_18315	COG2261	transglycosylase associated protein
I9X38_18320	COG4876	unkown
I9X38_18325	COG2217	Heavy metal translocating P-type atpase
I9X38_18330	COG3729	General stress protein
I9X38_18335	COG0662	Cupin 2, conserved barrel domain protein
I9X38_18340	COG2329	Antibiotic biosynthesis monooxygenase
I9X38_18350	COG3546	catalase activity
I9X38_18355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I9X38_18360	COG3290	protein histidine kinase activity
I9X38_18365	COG4565	transcriptional regulatory protein
I9X38_18370	COG1301	dicarboxylic acid transport
I9X38_18375	COG0628	permease
I9X38_18380	COG1301	dicarboxylic acid transport
I9X38_18385	COG1131	(ABC) transporter
I9X38_18390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I9X38_18400	COG1960	acyl-CoA dehydrogenase activity
I9X38_18415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I9X38_18420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_18425	COG1181	Belongs to the D-alanine--D-alanine ligase family
I9X38_18430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I9X38_18435	COG0513	Belongs to the DEAD box helicase family
I9X38_18440	COG3402	PFAM membrane-flanked domain
I9X38_18445	COG3428	Bacterial PH domain
I9X38_18450	COG0705	Rhomboid family
I9X38_18455	COG0736	holo-[acyl-carrier-protein] synthase activity
I9X38_18460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
I9X38_18465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I9X38_18470	COG0864	Transcriptional regulator
I9X38_18475	COG2337	Toxic component of a toxin-antitoxin (TA) module
I9X38_18480	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_18485	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_18490	COG2172	sigma factor antagonist activity
I9X38_18495	COG2208	phosphoserine phosphatase activity
I9X38_18500	COG1366	Belongs to the anti-sigma-factor antagonist family
I9X38_18505	COG2172	sigma factor antagonist activity
I9X38_18510	COG1191	sigma factor activity
I9X38_18515	COG2208	phosphoserine phosphatase activity
I9X38_18530	COG1846	Transcriptional regulator
I9X38_18535	COG2183	response to ionizing radiation
I9X38_18545	COG3091	SprT-like family
I9X38_18560	COG3239	Fatty acid desaturase
I9X38_18565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_18615	COG2273	Hydrolase Family 16
I9X38_18630	COG0457	Tetratricopeptide repeat
I9X38_18670	COG0726	polysaccharide deacetylase
I9X38_18690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I9X38_18695	COG2720	vancomycin resistance protein
I9X38_18700	COG3739	integral membrane protein
I9X38_18705	COG3655	Transcriptional regulator
I9X38_18715	COG2135	peptidase activity
I9X38_18720	COG5434	Belongs to the glycosyl hydrolase 28 family
I9X38_18740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I9X38_18750	COG3832	glyoxalase III activity
I9X38_18780	COG4195	phage-related replication protein
I9X38_18800	COG0346	lactoylglutathione lyase activity
I9X38_18810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
I9X38_18815	COG1388	LysM domain
I9X38_18820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
I9X38_18825	COG4224	UPF0291 protein
I9X38_18830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I9X38_18840	COG3763	UPF0154 protein
I9X38_18850	COG0785	Cytochrome C biogenesis protein
I9X38_18855	COG2201	protein-glutamate methylesterase activity
I9X38_18860	COG4846	Membrane protein involved in cytochrome C biogenesis
I9X38_18870	COG0071	Belongs to the small heat shock protein (HSP20) family
I9X38_18885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I9X38_18890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I9X38_18910	COG0824	Thioesterase
I9X38_18920	COG4841	protein insertion into membrane
I9X38_18925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
I9X38_18930	COG1832	CoA-binding protein
I9X38_18935	COG0187	DNA topoisomerase II activity
I9X38_18940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
I9X38_18950	COG1115	amino acid carrier protein
I9X38_18955	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
I9X38_18980	COG3507	Belongs to the glycosyl hydrolase 43 family
I9X38_18995	COG2246	polysaccharide biosynthetic process
I9X38_19000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I9X38_19005	COG0586	Pfam SNARE associated Golgi protein
I9X38_19010	COG2404	hydrolase activity, acting on ester bonds
I9X38_19015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
I9X38_19020	COG1024	Enoyl-CoA hydratase
I9X38_19025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
I9X38_19030	COG0511	ligase activity, forming carbon-carbon bonds
I9X38_19035	COG0439	Biotin carboxylase
I9X38_19040	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_19045	COG1960	acyl-CoA dehydrogenase activity
I9X38_19055	COG1649	PFAM Uncharacterised BCR, COG1649
I9X38_19065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_19065	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I9X38_19075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_19075	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_19075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_19075	COG3321	synthase
I9X38_19075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_19080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I9X38_19085	COG3321	synthase
I9X38_19085	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_19085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_19085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_19085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_19090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_19090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_19090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I9X38_19090	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_19090	COG3321	synthase
I9X38_19100	COG0140	phosphoribosyl-ATP diphosphatase activity
I9X38_19100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
I9X38_19105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I9X38_19155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I9X38_19185	COG5444	nuclease activity
I9X38_19205	COG5505	Protein of unknown function (DUF819)
I9X38_19210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I9X38_19215	COG0626	cystathionine gamma-synthase activity
I9X38_19220	COG0626	cystathionine gamma-synthase activity
I9X38_19225	COG2382	esterase
I9X38_19230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I9X38_19235	COG2153	protein acetylation
I9X38_19245	COG0210	DNA helicase
I9X38_19300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
I9X38_19305	COG0351	phosphomethylpyrimidine kinase
I9X38_19310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I9X38_19315	COG2022	thiamine diphosphate biosynthetic process
I9X38_19320	COG2104	thiamine diphosphate biosynthetic process
I9X38_19325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I9X38_19330	COG0352	thiamine-phosphate diphosphorylase activity
I9X38_19335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
I9X38_19340	COG0475	glutathione-regulated potassium exporter activity
I9X38_19340	COG0569	domain protein
I9X38_19345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
I9X38_19350	COG0564	pseudouridine synthase activity
I9X38_19355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
I9X38_19360	COG2357	RelA SpoT domain protein
I9X38_19370	COG4116	CYTH
I9X38_19375	COG0741	lytic transglycosylase activity
I9X38_19380	COG2346	COG2346, Truncated hemoglobins
I9X38_19385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
I9X38_19395	COG1164	Oligoendopeptidase f
I9X38_19400	COG4469	Competence protein
I9X38_19405	COG4862	establishment of competence for transformation
I9X38_19415	COG0861	Integral membrane protein TerC family
I9X38_19420	COG1393	Belongs to the ArsC family
I9X38_19425	COG0456	acetyltransferase
I9X38_19430	COG2814	Major facilitator Superfamily
I9X38_19435	COG4608	Belongs to the ABC transporter superfamily
I9X38_19440	COG0444	Belongs to the ABC transporter superfamily
I9X38_19445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I9X38_19450	COG0601	transmembrane transport
I9X38_19455	COG4166	transmembrane transport
I9X38_19460	COG0180	Tryptophanyl-tRNA synthetase
I9X38_19470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I9X38_19475	COG0601	transmembrane transport
I9X38_19485	COG4608	Belongs to the ABC transporter superfamily
I9X38_19490	COG0444	Belongs to the ABC transporter superfamily
I9X38_19495	COG5504	Zn-dependent protease
I9X38_19500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I9X38_19505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I9X38_19520	COG1744	ABC transporter substrate-binding protein PnrA-like
I9X38_19530	COG2267	carboxylic ester hydrolase activity
I9X38_19545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I9X38_19550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I9X38_19555	COG0505	Belongs to the CarA family
I9X38_19560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I9X38_19570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
I9X38_19575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
I9X38_19580	COG2271	Major facilitator Superfamily
I9X38_19585	COG0277	FAD linked oxidase domain protein
I9X38_19595	COG2151	metal-sulfur cluster biosynthetic enzyme
I9X38_19600	COG1073	alpha beta
I9X38_19605	COG0561	phosphatase activity
I9X38_19625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_19630	COG1307	EDD domain protein, DegV family
I9X38_19635	COG3227	Zinc metalloprotease (Elastase)
I9X38_19650	COG1695	Transcriptional regulator
I9X38_19670	COG2996	Protein conserved in bacteria
I9X38_19675	COG1666	GTP binding
I9X38_19680	COG0646	methionine synthase
I9X38_19680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
I9X38_19685	COG2153	protein acetylation
I9X38_19690	COG0454	-acetyltransferase
I9X38_19695	COG2814	Major facilitator Superfamily
I9X38_19700	COG4948	Mandelate Racemase Muconate Lactonizing
I9X38_19705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I9X38_19710	COG1809	phosphosulfolactate synthase activity
I9X38_19715	COG2045	Belongs to the ComB family
I9X38_19720	COG0175	sulfate reduction
I9X38_19725	COG2046	Belongs to the sulfate adenylyltransferase family
I9X38_19730	COG0529	Catalyzes the synthesis of activated sulfate
I9X38_19735	COG2267	carboxylic ester hydrolase activity
I9X38_19740	COG1357	PFAM Pentapeptide repeats (8 copies)
I9X38_19755	COG2318	DinB family
I9X38_19760	COG0673	inositol 2-dehydrogenase activity
I9X38_19765	COG1609	Transcriptional regulator
I9X38_19770	COG1917	Cupin 2, conserved barrel domain protein
I9X38_19770	COG2207	Transcriptional regulator
I9X38_19775	COG0534	Mate efflux family protein
I9X38_19780	COG1562	ergosterol biosynthetic process
I9X38_19785	COG2318	DinB family
I9X38_19790	COG0367	asparagine synthase
I9X38_19800	COG1404	Belongs to the peptidase S8 family
I9X38_19810	COG0179	Fumarylacetoacetate (FAA) hydrolase
I9X38_19815	COG5337	Spore coat protein CotH
I9X38_19855	COG1403	HNH endonuclease
I9X38_19860	COG0419	ATPase involved in DNA repair
I9X38_19865	COG0420	3'-5' exonuclease activity
I9X38_19870	COG1074	ATP-dependent DNA helicase activity
I9X38_19875	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
I9X38_19880	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
I9X38_19890	COG4533	DNA binding
I9X38_19895	COG0477	Major facilitator Superfamily
I9X38_19895	COG2814	Major facilitator Superfamily
I9X38_19900	COG3180	Ammonia monooxygenase
I9X38_19905	COG1609	Transcriptional regulator
I9X38_19910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I9X38_19915	COG0561	phosphatase activity
I9X38_19920	COG0673	inositol 2-dehydrogenase activity
I9X38_19925	COG0738	Major facilitator superfamily
I9X38_19935	COG1846	Transcriptional regulator
I9X38_19940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I9X38_19945	COG0681	Belongs to the peptidase S26 family
I9X38_19950	COG0398	Pfam SNARE associated Golgi protein
I9X38_19965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I9X38_19980	COG4903	ComK protein
I9X38_19990	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_19995	COG0723	plastoquinol--plastocyanin reductase activity
I9X38_19995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I9X38_20000	COG0840	transmembrane signaling receptor activity
I9X38_20005	COG1268	BioY protein
I9X38_20010	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_20015	COG0183	Belongs to the thiolase family
I9X38_20020	COG0406	alpha-ribazole phosphatase activity
I9X38_20025	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
I9X38_20030	COG0604	alcohol dehydrogenase
I9X38_20035	COG0456	acetyltransferase
I9X38_20040	COG1404	Belongs to the peptidase S8 family
I9X38_20045	COG0501	Belongs to the peptidase M48B family
I9X38_20055	COG0318	PFAM AMP-dependent synthetase and ligase
I9X38_20060	COG0702	epimerase
I9X38_20065	COG0095	Lipoate-protein ligase
I9X38_20070	COG1234	tRNA 3'-trailer cleavage
I9X38_20080	COG1301	dicarboxylic acid transport
I9X38_20085	COG4405	Protein conserved in bacteria
I9X38_20090	COG1363	Peptidase, m42
I9X38_20100	COG4377	Putative membrane peptidase family (DUF2324)
I9X38_20105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
I9X38_20110	COG1511	domain protein
I9X38_20115	COG1309	transcriptional regulator
I9X38_20120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
I9X38_20125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
I9X38_20130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
I9X38_20135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I9X38_20140	COG2329	Antibiotic biosynthesis monooxygenase
I9X38_20145	COG3069	C4-dicarboxylate transmembrane transporter activity
I9X38_20150	COG1473	amidohydrolase
I9X38_20160	COG4473	ABC transporter
I9X38_20165	COG1131	(ABC) transporter
I9X38_20170	COG0537	adenosine 5'-monophosphoramidase activity
I9X38_20175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
I9X38_20190	COG4980	gas vesicle protein
I9X38_20195	COG1846	Transcriptional regulator
I9X38_20225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I9X38_20235	COG3481	metal-dependent phosphohydrolase, HD sub domain
I9X38_20240	COG4717	serine-type aminopeptidase activity
I9X38_20245	COG0420	3'-5' exonuclease activity
I9X38_20250	COG1668	transmembrane transport
I9X38_20255	COG4152	abc transporter atp-binding protein
I9X38_20265	COG1024	Enoyl-CoA hydratase
I9X38_20275	COG0490	domain, Protein
I9X38_20280	COG0475	glutathione-regulated potassium exporter activity
I9X38_20285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I9X38_20290	COG0561	phosphatase activity
I9X38_20295	COG4335	DNA alkylation repair
I9X38_20300	COG3679	Belongs to the UPF0342 family
I9X38_20305	COG4399	Belongs to the UPF0754 family
I9X38_20310	COG0189	ligase activity
I9X38_20315	COG0189	ligase activity
I9X38_20335	COG0702	epimerase
I9X38_20340	COG1132	(ABC) transporter
I9X38_20345	COG1132	(ABC) transporter
I9X38_20350	COG0589	response to stress
I9X38_20355	COG1757	Na H antiporter
I9X38_20360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I9X38_20365	COG0726	polysaccharide deacetylase
I9X38_20370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
I9X38_20375	COG0668	transmembrane transport
I9X38_20385	COG0584	glycerophosphoryl diester phosphodiesterase
I9X38_20390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I9X38_20395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
I9X38_20400	COG1253	flavin adenine dinucleotide binding
I9X38_20405	COG0436	Aminotransferase
I9X38_20410	COG0789	Transcriptional regulator
I9X38_20415	COG1253	flavin adenine dinucleotide binding
I9X38_20420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I9X38_20425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I9X38_20430	COG0204	Acyl-transferase
I9X38_20435	COG0667	Aldo Keto reductase
I9X38_20440	COG1595	DNA-templated transcription, initiation
I9X38_20455	COG0456	acetyltransferase
I9X38_20460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I9X38_20465	COG0733	neurotransmitter:sodium symporter activity
I9X38_20470	COG0531	amino acid
I9X38_20475	COG1028	Short-chain dehydrogenase reductase Sdr
I9X38_20480	COG0372	Belongs to the citrate synthase family
I9X38_20485	COG0583	DNA-binding transcription factor activity
I9X38_20490	COG0791	NLP P60 protein
I9X38_20490	COG1388	LysM domain
I9X38_20495	COG1785	Belongs to the alkaline phosphatase family
I9X38_20500	COG2719	SpoVR family
I9X38_20505	COG0668	transmembrane transport
I9X38_20510	COG1959	2 iron, 2 sulfur cluster binding
I9X38_20515	COG1388	LysM domain
I9X38_20515	COG0791	NLP P60 protein
I9X38_20530	COG0431	NADPH-dependent FMN reductase
I9X38_20535	COG2197	response regulator
I9X38_20540	COG2203	Gaf domain
I9X38_20540	COG4585	Histidine kinase
I9X38_20545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I9X38_20550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I9X38_20555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
I9X38_20560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I9X38_20565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
I9X38_20570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
I9X38_20580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I9X38_20580	COG3153	acetyltransferase
I9X38_20585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I9X38_20590	COG0517	IMP dehydrogenase activity
I9X38_20600	COG0564	pseudouridine synthase activity
I9X38_20605	COG3764	Sortase (surface protein transpeptidase)
I9X38_20610	COG0737	Belongs to the 5'-nucleotidase family
I9X38_20610	COG1525	nuclease
I9X38_20610	COG4085	toxin activity
I9X38_20615	COG5577	PFAM Coat F domain
I9X38_20635	COG1823	symporter activity
I9X38_20640	COG3706	GGDEF domain
I9X38_20645	COG1464	Belongs to the NlpA lipoprotein family
I9X38_20650	COG1278	Cold shock
I9X38_20655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
I9X38_20660	COG1131	(ABC) transporter
I9X38_20665	COG1131	(ABC) transporter
I9X38_20670	COG1725	Transcriptional regulator
I9X38_20685	COG0655	NAD(P)H dehydrogenase (quinone) activity
I9X38_20690	COG2814	Major facilitator Superfamily
I9X38_20695	COG1566	PFAM secretion protein HlyD family protein
I9X38_20700	COG1846	Transcriptional regulator
I9X38_20705	COG2718	Belongs to the UPF0229 family
I9X38_20710	COG2766	serine protein kinase
I9X38_20715	COG1664	Polymer-forming cytoskeletal
I9X38_20720	COG1664	Polymer-forming cytoskeletal
I9X38_20725	COG0789	Transcriptional regulator
I9X38_20730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I9X38_20740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I9X38_20745	COG3382	B3 4 domain protein
I9X38_20755	COG1476	TRANSCRIPTIONal
I9X38_20765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I9X38_20780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I9X38_20785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I9X38_20790	COG1116	anion transmembrane transporter activity
I9X38_20795	COG0753	catalase activity
I9X38_20805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
I9X38_20810	COG3340	Belongs to the peptidase S51 family
I9X38_20820	COG5577	PFAM Coat F domain
I9X38_20825	COG1063	alcohol dehydrogenase
I9X38_20835	COG4326	sporulation control protein
I9X38_20855	COG0552	protein localization to endoplasmic reticulum
I9X38_20860	COG0552	protein localization to endoplasmic reticulum
I9X38_20865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity