locus-tag class description DJ92_1 ENOG4105CZV ABC transporter DJ92_100 ENOG4105CSH Transporter DJ92_1001 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DJ92_1002 ENOG4105CNI cell division protein FtsW DJ92_1005 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DJ92_1006 ENOG4105CJN penicillin-binding protein DJ92_1007 ENOG4105CJN penicillin-binding protein DJ92_1010 ENOG41074B2 UPF0747 protein DJ92_1015 ENOG4105KNH Nucleic acid-binding protein DJ92_1017 ENOG41063PX domain protein DJ92_1018 ENOG4105D78 K07001 NTE family protein DJ92_1019 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) DJ92_102 ENOG4105PAD Hydrolase DJ92_1020 ENOG4105H20 Sporulation integral membrane protein YlbJ DJ92_1021 ENOG4106H78 methyltransferase DJ92_1025 ENOG4105WUC UPF0298 protein DJ92_1027 ENOG4107TB6 phosphoglycerate mutase DJ92_1030 ENOG4106UY4 Inherit from COG: Scp-like extracellular DJ92_1039 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) DJ92_104 ENOG4105VMP Transcriptional regulator DJ92_1040 ENOG4105CNI cell division protein FtsW DJ92_1043 ENOG4108IAB Phoh family DJ92_1047 ENOG4105QA2 DJ92_1048 ENOG4105CI3 gtp-binding protein typa DJ92_1050 ENOG4105ECY inositol monophosphatase DJ92_1054 ENOG4105CXN decarboxylase DJ92_1062 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DJ92_1066 ENOG4105CPP Dehydrogenase, E1 component DJ92_1068 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DJ92_1069 ENOG4108X4Q Hydrolase DJ92_107 ENOG4105D7V transposase DJ92_1070 ENOG4106EHS UPF0356 protein DJ92_1071 ENOG4105CN5 Metallo-Beta-Lactamase DJ92_1072 ENOG4107ZYR domain protein DJ92_1075 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ92_1076 ENOG4105D3R alkyl hydroperoxide reductase DJ92_1082 ENOG4108XRC Protein of unknown function (DUF458) DJ92_1083 ENOG4107IN1 Protein of unknown function (DUF1797) DJ92_1086 ENOG4105EPM Diguanylate phosphodiesterase DJ92_1087 ENOG4105K6S Short-chain dehydrogenase reductase Sdr DJ92_1090 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) DJ92_1092 ENOG4105UIN DJ92_110 ENOG4108PCN EamA-like transporter family DJ92_1103 ENOG4108HGU Histidine kinase DJ92_1105 ENOG4105CHM Aminotransferase DJ92_1106 ENOG4105ETE Transcriptional regulator (LacI family DJ92_1108 ENOG4105CG3 alpha amylase, catalytic region DJ92_1110 ENOG4107EXU Short-chain dehydrogenase reductase Sdr DJ92_1118 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) DJ92_1119 ENOG4105CHU acetyl-coa acetyltransferase DJ92_112 ENOG4108PCN EamA-like transporter family DJ92_1125 ENOG4105DTD Dehydrogenase DJ92_1127 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) DJ92_1128 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) DJ92_1129 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase DJ92_1137 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ92_1138 ENOG4108A04 Beta-lactamase DJ92_1139 ENOG4105BZU Histidine kinase DJ92_1143 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DJ92_1146 ENOG4105CID antiterminator DJ92_1147 ENOG4105J7I hydrolase DJ92_1148 ENOG4105FDP GntR family transcriptional regulator DJ92_1150 ENOG4105CE4 GlcNAc 6-P deacetylase DJ92_1152 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) DJ92_1153 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) DJ92_1157 ENOG4107ZE5 PPIases accelerate the folding of proteins DJ92_1158 ENOG4105PTM secreted protein DJ92_1159 ENOG4105J7I hydrolase DJ92_116 ENOG410635A Membrane DJ92_1161 ENOG4105G6R Stage v sporulation protein ae DJ92_1163 ENOG4105CZ3 stage V sporulation protein ad DJ92_1164 ENOG41090VF Stage v sporulation protein ac DJ92_1167 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ92_1169 ENOG41082AN stage II sporulation protein DJ92_117 ENOG4108IQI permease DJ92_1170 ENOG4105DZ1 carboxypeptidase DJ92_1171 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DJ92_1172 ENOG4105DVE abc transporter atp-binding protein DJ92_1179 ENOG4105D7N magnesium and cobalt transport protein CorA DJ92_1184 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ92_1186 ENOG4105I3K Ferric uptake regulator, Fur family DJ92_1187 ENOG4105MZ9 stage II sporulation protein m DJ92_1191 ENOG4105CPC Aldo Keto reductase DJ92_1194 ENOG4105RHY Pfam:UPF0157 DJ92_1199 ENOG4107SKW Inherit from COG: Alpha beta hydrolase DJ92_120 ENOG4105CHJ isochorismatase hydrolase DJ92_1201 ENOG4105ETE Transcriptional regulator (LacI family DJ92_1202 ENOG4108YM7 Gcn5-related n-acetyltransferase DJ92_1207 ENOG4105WMR Protein CrcB homolog DJ92_1208 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DJ92_1209 ENOG4108R6K riboflavin synthase, subunit alpha DJ92_121 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DJ92_1210 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DJ92_1215 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DJ92_1216 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DJ92_1217 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DJ92_1219 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ92_1221 ENOG4105DFD Na H antiporter DJ92_1222 ENOG4105CGH 5'-nucleotidase DJ92_1227 ENOG4105DBV ornithine carbamoyltransferase DJ92_1231 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase DJ92_1233 ENOG4108IXY short-chain dehydrogenase reductase DJ92_1234 ENOG41069FQ Metallo-beta-lactamase superfamily DJ92_1235 ENOG4105II7 pyrroline-5-carboxylate reductase DJ92_1236 ENOG4105EJQ L-serine dehydratase DJ92_1239 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DJ92_1244 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DJ92_1245 ENOG4105D9U N-acetyltransferase DJ92_1248 ENOG4108VZI ErfK ybiS ycfS ynhG family protein DJ92_1249 ENOG4108QEG Membrane DJ92_1251 ENOG4105CDA abc transporter atp-binding protein DJ92_1252 ENOG4105E5Q amino acid AbC transporter DJ92_1253 ENOG4108HW3 (ABC) transporter DJ92_1255 ENOG4105G7B Protein of unknown function (DUF2992) DJ92_1256 ENOG4105E09 nadh pyrophosphatase DJ92_1257 ENOG4108QY0 Membrane DJ92_1259 ENOG4105C7S Dehydrogenase DJ92_1260 ENOG4105CPP Dehydrogenase, E1 component DJ92_1264 ENOG4107RDP Dehydrogenase DJ92_1266 ENOG4108JUB Transcriptional regulator DJ92_1267 ENOG4106CCJ Protein of unknown function (DUF2627) DJ92_1268 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DJ92_127 ENOG4108V4B ThiJ pfpI DJ92_1273 ENOG4107QQR Sporulation DJ92_1274 ENOG4105S1Z Stage IV sporulation protein B DJ92_1275 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DJ92_1277 ENOG4105DX0 Hemolysin A DJ92_1280 ENOG41082UU Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DJ92_1282 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) DJ92_1284 ENOG4108ZSR alkaline shock protein DJ92_1285 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DJ92_1291 ENOG410644B Stage III sporulation protein af DJ92_1293 ENOG4105KQ4 Stage iii sporulation protein ad DJ92_1294 ENOG4108CQH stage III sporulation protein AC DJ92_1295 ENOG4105KR5 Stage iii sporulation protein DJ92_1296 ENOG4105CD2 stage iii sporulation protein aa DJ92_1301 ENOG4105DC7 peptidase M24 DJ92_1302 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) DJ92_1304 ENOG4105CBJ Metal-dependent enzyme DJ92_1306 ENOG4107YBY Hydrolase DJ92_1313 ENOG41082GG biotin lipoate A B protein ligase DJ92_1314 ENOG4105WZW rhodanese family DJ92_1319 ENOG41080TC multidrug resistance protein DJ92_1323 ENOG4105CZV ABC transporter DJ92_1327 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DJ92_1329 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DJ92_133 ENOG4107RF6 penicillin-binding protein DJ92_1330 ENOG4105C0D helicase DJ92_1334 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ92_1335 ENOG4105D3R alkyl hydroperoxide reductase DJ92_1338 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) DJ92_1342 ENOG4106855 Competence protein DJ92_135 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) DJ92_1354 ENOG4107TVP HD domain protein DJ92_1358 ENOG4105C3R Methionine synthase DJ92_1360 ENOG4105C28 cystathionine DJ92_1361 ENOG4105C28 cystathionine DJ92_1365 ENOG4105C5X domain protein DJ92_1367 ENOG4105DKQ ROK family DJ92_1369 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DJ92_1370 ENOG4105WDJ 50S ribosomal protein L33 DJ92_1372 ENOG4108UTW Plays a role in the regulation of phosphate uptake DJ92_1373 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DJ92_1374 ENOG4105E2Z phosphate ABC transporter (Permease DJ92_1375 ENOG4105C8U phosphate abc transporter DJ92_1376 ENOG4105PWN phosphate abc transporter DJ92_1377 ENOG4107RF6 penicillin-binding protein DJ92_1379 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ92_138 ENOG4105E7W lamb ycsf family protein DJ92_1383 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) DJ92_1384 ENOG4105N80 Ferric uptake regulator, Fur family DJ92_1386 ENOG4105FDK ABC transporter DJ92_1387 ENOG4108JYZ YitT family DJ92_1392 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) DJ92_1393 ENOG4105EGD dinuclear metal center protein, YbgI family DJ92_1396 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ92_1397 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DJ92_1398 ENOG4107XJU UPF0178 protein DJ92_1399 ENOG4107XJU UPF0178 protein DJ92_14 ENOG4108AQF aminoglycoside N(3)-acetyltransferase DJ92_140 ENOG4105P4J Allophanate hydrolase, subunit 1 DJ92_1404 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DJ92_1405 ENOG4105KG3 cytidine deaminase DJ92_1406 ENOG4107YR5 Diacylglycerol kinase DJ92_1407 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) DJ92_1408 ENOG4105CTJ Metal Dependent Phosphohydrolase DJ92_1409 ENOG4105C9A Phoh family DJ92_141 ENOG4107258 Transcriptional regulator DJ92_1411 ENOG41068P3 sporulation protein YqfC DJ92_1412 ENOG4105KTH gatB Yqey DJ92_1414 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) DJ92_1415 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DJ92_1416 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DJ92_1418 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) DJ92_1422 ENOG4105CSA Coproporphyrinogen iii oxidase DJ92_1423 ENOG4105KVH Transcriptional regulator DJ92_1428 ENOG4105TQK DNA polymerase iii, delta' subunit DJ92_143 ENOG4106N3A copper homeostasis protein cutc DJ92_1430 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DJ92_1431 ENOG4108UK2 deaminase DJ92_1432 ENOG4105KQC Competence protein DJ92_1434 ENOG4105DXX methyltransferase DJ92_1436 ENOG4108WF2 Metal Dependent Phosphohydrolase DJ92_1438 ENOG410812S Rna-binding protein DJ92_144 ENOG4105DR5 peptidase DJ92_1440 ENOG4105CQW ribosome biogenesis GTPase YqeH DJ92_1441 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase DJ92_1443 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ92_1444 ENOG4105WDJ 50S ribosomal protein L33 DJ92_1447 ENOG4105G6Z alkaline phosphatase DJ92_1449 ENOG4108MUZ hydrolase DJ92_1455 ENOG4105MIR Phenylalanine 4-monooxygenase DJ92_1457 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase DJ92_146 ENOG4108UMI ABC transporter, permease DJ92_1466 ENOG4108EKI Dehydrogenase DJ92_1468 ENOG4105DQ6 Transposase DJ92_1469 ENOG4105C28 cystathionine DJ92_147 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DJ92_1475 ENOG4107XRG penicillin-binding protein DJ92_1477 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) DJ92_148 ENOG4105FDT acyl-CoA dehydrogenase DJ92_1480 ENOG4105CFP Peptidase U32 DJ92_1481 ENOG4105XYU peptidase (U32 family) DJ92_1482 ENOG4108VQJ O-methyltransferase DJ92_1483 ENOG4105HHA aminodeoxychorismate lyase DJ92_1486 ENOG4105VBH UPF0297 protein DJ92_1488 ENOG4105C02 permease DJ92_149 ENOG4105D01 (LipO)protein DJ92_1491 ENOG41060CR DJ92_1492 ENOG4105C7H Helicase, RecD TraA family DJ92_1495 ENOG4105C3J Cysteine desulfurase DJ92_1497 ENOG4105D1H recombination factor protein RarA DJ92_1498 ENOG4108VCI transcription factor, rsfa family DJ92_1499 ENOG4105CUZ uba thif-type nad fad binding protein DJ92_1506 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DJ92_1508 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DJ92_1509 ENOG41076HS cation diffusion facilitator family transporter DJ92_1510 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DJ92_1512 ENOG4105CKP Polysaccharide Biosynthesis Protein DJ92_1513 ENOG4108QG2 Membrane DJ92_1515 ENOG4105VIE preprotein translocase, subunit YajC DJ92_1518 ENOG41061AI Protein of unknown function (DUF2905) DJ92_1519 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) DJ92_152 ENOG4105D9U N-acetyltransferase DJ92_1521 ENOG4108HUF Transporter DJ92_1527 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DJ92_1528 ENOG4108IYU L-aspartate oxidase DJ92_1531 ENOG4108RPX mosc domain containing protein DJ92_1532 ENOG4105CQC Prephenate dehydratase DJ92_1536 ENOG4105EWM Histidine kinase DJ92_1541 ENOG4105X36 (ribosomal) protein DJ92_1542 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) DJ92_1543 ENOG4105C03 ribonuclease DJ92_1546 ENOG4107QMS site-determining protein DJ92_1549 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DJ92_1550 ENOG4105DFF Rod shape-determining protein mreb DJ92_1551 ENOG4105W5Q DNA repair protein (RadC DJ92_1552 ENOG4108Z03 MAF-like protein DJ92_1554 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DJ92_1555 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DJ92_1557 ENOG41068KH stage VI sporulation protein D DJ92_1559 ENOG4105D52 delta-aminolevulinic acid dehydratase DJ92_1561 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DJ92_1563 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) DJ92_1564 ENOG4105K56 Transcriptional regulator DJ92_1568 ENOG4108IUQ atp-dependent protease DJ92_157 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) DJ92_1570 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ92_1574 ENOG4108QCI YvbH-like oligomerisation region DJ92_1577 ENOG4105M59 Phosphodiesterase, mj0936 family DJ92_1579 ENOG4108FK2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) DJ92_1580 ENOG4108XJQ germination protein DJ92_1582 ENOG4105PFC Transcriptional regulator DJ92_1583 ENOG4105C0X amino acid DJ92_1584 ENOG41067S9 phage shock protein C, PspC DJ92_1586 ENOG4105CNT hydrolase family 2 DJ92_1587 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component DJ92_1588 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component DJ92_159 ENOG4105K6H D-cysteine desulfhydrase DJ92_1590 ENOG4105EQD regulatoR DJ92_1591 ENOG4105C2F Histidine kinase DJ92_1592 ENOG4108JCI Transcriptional regulator DJ92_1594 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) DJ92_1595 ENOG4108Z40 Transcriptional regulator DJ92_1596 ENOG4105RHA ABC transporter, permease DJ92_1597 ENOG4108IUX (ABC) transporter DJ92_1598 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family DJ92_1599 ENOG4108VXD carboxy-peptidase DJ92_1601 ENOG4105E33 succinate dehydrogenase DJ92_1603 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit DJ92_1609 ENOG4106WTF Glycosyl transferase, family 2 DJ92_1614 ENOG4105K63 Thioredoxin DJ92_1615 ENOG4105C10 Electron transfer flavoprotein DJ92_1616 ENOG4105BZJ Electron transfer flavoprotein DJ92_1617 ENOG41060WC Enoyl-CoA hydratase DJ92_1618 ENOG4107Z3H Transcriptional regulator, TetR family DJ92_1619 ENOG4105CEY Amp-dependent synthetase and ligase DJ92_1629 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ92_163 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DJ92_1632 ENOG4105DR4 Methyltransferase DJ92_1635 ENOG4105FE9 pseudouridine synthase DJ92_1637 ENOG4105DCG PHP domain protein DJ92_1639 ENOG410687F Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) DJ92_164 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) DJ92_1640 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DJ92_1643 ENOG4105C5S asparaginyl-tRNA synthetase DJ92_1645 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DJ92_1647 ENOG4108RWN rrna methyltransferase DJ92_165 ENOG4105DY9 regulatoR DJ92_1652 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ92_1653 ENOG4105CW7 secretion protein, HlyD family DJ92_1654 ENOG4108JGH Tetr family transcriptional regulator DJ92_1656 ENOG4105CN9 Peptidase m42 family protein DJ92_1661 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) DJ92_1662 ENOG4105C22 threonyL-tRNA synthetase DJ92_1663 ENOG4108TDW sporulation protein YtxC DJ92_1666 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) DJ92_1667 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DJ92_1668 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DJ92_1671 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DJ92_1672 ENOG4105C2M dna polymerase I DJ92_1673 ENOG4105BZU Histidine kinase DJ92_1674 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ92_1675 ENOG4105KK4 UPF0060 membrane protein DJ92_1679 ENOG4108HMX isocitrate dehydrogenase (NADP) DJ92_168 ENOG4105C19 ABC transporter DJ92_1680 ENOG4105BZN citrate synthase DJ92_1681 ENOG4108VMM UPF0756 membrane protein DJ92_1682 ENOG4108REF Sporulation integral membrane protein ytvi DJ92_1683 ENOG4105FS0 cytoplasmic membrane protein DJ92_1688 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DJ92_1689 ENOG4105C6K Malic enzyme DJ92_169 ENOG4108BUD transposase DJ92_1690 ENOG4105C0B DNA polymerase III (alpha subunit) DJ92_1691 ENOG4105VV2 DJ92_1693 ENOG4105SFS phosphoesterase RecJ domain protein DJ92_1698 ENOG4105E8R UPF0173 metal-dependent hydrolase DJ92_1699 ENOG4105DC7 peptidase M24 DJ92_1707 ENOG41082W1 Cupin 2, conserved barrel domain protein DJ92_171 ENOG4108WC5 Alpha Beta Hydrolase Fold protein DJ92_1712 ENOG4107YZX Universal stress protein DJ92_1715 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DJ92_1719 ENOG4105CDH Citrulline--aspartate ligase DJ92_172 ENOG4105BZU Histidine kinase DJ92_1721 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) DJ92_1726 ENOG4108JYZ YitT family DJ92_1729 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) DJ92_1732 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) DJ92_1733 ENOG4105KBJ sporulation protein ytfj DJ92_1736 ENOG4105EFZ amidohydrolase DJ92_1738 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DJ92_1742 ENOG4105DGY modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity) DJ92_1745 ENOG4105U5Y Transcriptional regulator DJ92_1747 ENOG4105C28 cystathionine DJ92_1750 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DJ92_1754 ENOG4105EMN RNA polymerase sigma factor DJ92_1756 ENOG4108UW5 maltose o-acetyltransferase DJ92_1758 ENOG4105F1V Acetoin utilization protein DJ92_1759 ENOG4105W87 Cbs domain DJ92_176 ENOG4108JQ1 Dehydrogenase DJ92_1760 ENOG4105DGU Histone deacetylase DJ92_1762 ENOG4105EP9 oxidoreductase DJ92_1765 ENOG4105ETE Transcriptional regulator (LacI family DJ92_1766 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DJ92_1769 ENOG4105C88 aminopeptidase DJ92_177 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) DJ92_1774 ENOG4108IPJ Membrane DJ92_1775 ENOG4105DFU Cell wall formation (By similarity) DJ92_1778 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ92_1780 ENOG4108VDD TRNA binding domain protein DJ92_1781 ENOG4108NKM UPF0354 protein DJ92_1786 ENOG4105CHU acetyl-coa acetyltransferase DJ92_1787 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DJ92_1788 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DJ92_1789 ENOG4105C1G acyl-Coa dehydrogenase DJ92_1790 ENOG4105CEY Amp-dependent synthetase and ligase DJ92_1791 ENOG4105C8F Beta-lactamase domain protein DJ92_1794 ENOG4108V15 phosphotransferase enzyme family DJ92_1795 ENOG4108IUM Glycogen debranching enzyme DJ92_1797 ENOG4107QSE Dipeptidase DJ92_1798 ENOG4105YW5 deoR family transcriptional regulator DJ92_180 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DJ92_1801 ENOG4105CBX hi0933 family DJ92_1808 ENOG4108VJ1 Transcriptional regulator (CarD family DJ92_1810 ENOG41067WU Molybdopterin converting factor (Subunit 1) DJ92_1811 ENOG4108ZAF Molybdopterin DJ92_1812 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein DJ92_1813 ENOG4105CVM Molybdenum cofactor synthesis domain protein DJ92_1815 ENOG4105D06 uba thif-type nad fad binding protein DJ92_1816 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DJ92_1817 ENOG4105KVH Transcriptional regulator DJ92_1818 ENOG4108RCM Nitroreductase DJ92_1819 ENOG4107V6Q Cyclic nucleotide-binding domain DJ92_1821 ENOG4108IUE nitrate reductase beta subunit DJ92_1822 ENOG4105R3A Nitrate reductase DJ92_1827 ENOG41085GJ domain protein DJ92_1829 ENOG4105DWV Homoserine O-trans-acetylase DJ92_1831 ENOG4108B31 Spore germination protein DJ92_1837 ENOG4105C8T Leucyl-tRNA synthetase DJ92_1838 ENOG410605W Major Facilitator DJ92_1840 ENOG4105C19 ABC transporter DJ92_1841 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DJ92_1844 ENOG4105N5T Radical SAM Protein DJ92_1846 ENOG4105E2Y ABC, transporter DJ92_185 ENOG4108T6E Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity) DJ92_1851 ENOG4105E8V Alpha Beta Hydrolase Fold protein DJ92_1852 ENOG4108Z0R Transferase DJ92_1853 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DJ92_1854 ENOG4105BZF Glycosyl transferase (Group 1 DJ92_1855 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) DJ92_1856 ENOG4105EPU Molybdenum cofactor synthesis domain protein DJ92_1859 ENOG4108MK9 spermidine N(1)-acetyltransferase DJ92_1860 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP DJ92_1869 ENOG4105BZU Histidine kinase DJ92_1870 ENOG4105BZU Histidine kinase DJ92_1871 ENOG4105EXC Acyl-transferase DJ92_1875 ENOG4105D2X ABC transporter substrate-binding protein DJ92_1877 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component DJ92_1879 ENOG4107XGZ Hydrolase DJ92_1880 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ92_1889 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) DJ92_1890 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase DJ92_1891 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) DJ92_1893 ENOG4108V2W Carbonate dehydratase DJ92_1895 ENOG4105C4M (Ubiquinol oxidase) subunit I DJ92_1896 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DJ92_1899 ENOG41080UQ Transcriptional regulator DJ92_1904 ENOG41087YS Phage shock protein A DJ92_1909 ENOG4105BZU Histidine kinase DJ92_1910 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_1918 ENOG4108UGV hypoxanthine phosphoribosyltransferase DJ92_1920 ENOG4107ZTW SNARE associated Golgi DJ92_1921 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DJ92_1923 ENOG4105C19 ABC transporter DJ92_1924 ENOG41086D8 Transcriptional regulator DJ92_1926 ENOG4105CJ1 ABC, transporter DJ92_1928 ENOG41082BM Transcriptional regulator, arsr family DJ92_1936 ENOG4105DTQ mandelate racemase muconate lactonizing DJ92_1938 ENOG4108IPT Naphthoate synthase DJ92_1939 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) DJ92_1940 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) DJ92_1941 ENOG4105E4F Isochorismate synthase DJ92_1942 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase DJ92_1944 ENOG4105VEQ Cold shock protein DJ92_1946 ENOG4107TXC Transcriptional regulator DJ92_1952 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) DJ92_1955 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ92_1956 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) DJ92_1976 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ92_1983 ENOG4105KT7 mgtC SapB transporter DJ92_1985 ENOG4107PBV potassium channel DJ92_1986 ENOG4107S5H glucose-6-phosphate isomerase DJ92_1987 ENOG4105WG9 Conserved Protein DJ92_1989 ENOG4105CHM Aminotransferase DJ92_199 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DJ92_1990 ENOG4108ZB6 transcriptional regulator AsnC family DJ92_1991 ENOG4105C5I Dehydrogenase DJ92_1992 ENOG4108MUZ hydrolase DJ92_1994 ENOG4105C87 Aminotransferase class I and II DJ92_1995 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ92_1997 ENOG4105Y38 Kinase-associated protein B DJ92_1999 ENOG4107R3E Citrate transporter DJ92_2002 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) DJ92_2003 ENOG4105KA0 thioesterase Superfamily protein DJ92_2006 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ92_2011 ENOG41069ER domain protein DJ92_2015 ENOG4105CEP NADH dehydrogenase DJ92_2023 ENOG4105EWC Purine nucleoside phosphorylase DJ92_2026 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DJ92_2028 ENOG4105D9N nucleoside DJ92_2032 ENOG4105C4B ABC transporter, permease DJ92_2036 ENOG41083MR nifu domain-containing protein DJ92_2038 ENOG4108W5N phosphatidylglycerophosphatase a DJ92_2039 ENOG4105MCT stage V sporulation protein S DJ92_204 ENOG41090AA DJ92_2041 ENOG4106FN3 tellurium resistance protein DJ92_2044 ENOG4105DAX Pfam:DUF2983 DJ92_2046 ENOG4105MUA Resistance protein DJ92_2052 ENOG4105DYS nad(p)h dehydrogenase (quinone) DJ92_2053 ENOG4105D4U had-superfamily hydrolase, subfamily iia DJ92_2056 ENOG4105CBT Fructose-1,6-bisphosphatase DJ92_2060 ENOG4105MMD transcriptional regulator DJ92_2061 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DJ92_2062 ENOG4107TXC Transcriptional regulator DJ92_2063 ENOG41090T1 Membrane DJ92_2065 ENOG4105EPI acetyltransferase, (GNAT) family DJ92_2068 ENOG4105FAA peptidase M23 DJ92_2069 ENOG4108YTE sporulation protein YunB DJ92_207 ENOG4108IUM Glycogen debranching enzyme DJ92_2070 ENOG4105KZD Domain of unknown function (DUF1805) DJ92_2071 ENOG4107R8B 5'-nucleotidase DJ92_2077 ENOG4105DIW FeS assembly protein SUFB DJ92_2078 ENOG4108UNV SUF system FeS assembly protein, NifU family DJ92_2079 ENOG4105C9B Cysteine desulfurase DJ92_2080 ENOG4105JRK feS assembly protein SufD DJ92_2081 ENOG4105C3K feS assembly ATPase SufC DJ92_2082 ENOG4105D01 (LipO)protein DJ92_2083 ENOG4108UMI ABC transporter, permease DJ92_2089 ENOG41080E8 Transcriptional regulator, Spx MgsR family DJ92_2093 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ92_2096 ENOG4108W8B Beta-lactamase domain protein DJ92_210 ENOG41065RQ ADP-ribosylation crystallin J1 DJ92_2100 ENOG4105C1G acyl-Coa dehydrogenase DJ92_2101 ENOG4105CHU acetyl-coa acetyltransferase DJ92_2104 ENOG4105DZ1 carboxypeptidase DJ92_2112 ENOG4108SUT Major Facilitator Superfamily DJ92_2113 ENOG4107R7I amino acid DJ92_2115 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DJ92_2117 ENOG4107AYK membrAne DJ92_2122 ENOG4107ZTW SNARE associated Golgi DJ92_2124 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DJ92_2126 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E DJ92_2127 ENOG4105VG1 fes assembly suf system protein DJ92_2128 ENOG4105D4Y metalloprotease DJ92_2130 ENOG4105C2I pirin domain protein DJ92_2133 ENOG4108RMU ferritin dps family protein DJ92_2135 ENOG4108URH decarboxylase DJ92_2136 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain DJ92_2139 ENOG4105D9N nucleoside DJ92_2140 ENOG4105D9N nucleoside DJ92_2142 ENOG4108RYK Nad-dependent epimerase dehydratase DJ92_2144 ENOG4105VKD bioY protein DJ92_2145 ENOG4105CV8 reductase DJ92_2146 ENOG4105F27 Major Facilitator DJ92_2147 ENOG4105KVH Transcriptional regulator DJ92_2157 ENOG4108NHD germination protein DJ92_2158 ENOG4108Q8B Spore germination protein DJ92_216 ENOG4108VQT Alpha beta hydrolase fold protein DJ92_2160 ENOG4108MK9 spermidine N(1)-acetyltransferase DJ92_2161 ENOG4108VY7 phosphate-starvation-inducible protein PsiE DJ92_2164 ENOG4105DUX Transporter DJ92_2171 ENOG4105ZX1 Transposase C DJ92_2172 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ92_2173 ENOG4108FPN Integrase DJ92_2174 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) DJ92_2175 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DJ92_2177 ENOG4105XZU Preprotein translocase, subunit SecG DJ92_2178 ENOG41067MG lrgb family DJ92_2181 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) DJ92_2182 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DJ92_2188 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ92_2192 ENOG41090VF Stage v sporulation protein ac DJ92_2193 ENOG4105CZ3 stage V sporulation protein ad DJ92_2196 ENOG4108QY0 Membrane DJ92_2197 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DJ92_2198 ENOG4105DS0 Transcriptional regulator, Crp Fnr family DJ92_2199 ENOG4105VCQ rubredoxin DJ92_2200 ENOG4108IFG nitrite reductase, (NAD(P)H) DJ92_2201 ENOG4105CNW domain protein DJ92_2204 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) DJ92_2205 ENOG4105IJJ transcriptional regulator, crp fnr family DJ92_2208 ENOG4105KRI phosphocarrier protein (HPr DJ92_2209 ENOG4105CIE May be required for sporulation (By similarity) DJ92_2210 ENOG4105CHW UPF0052 protein DJ92_2212 ENOG4108Z4K mutator MutT protein DJ92_2213 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) DJ92_2215 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DJ92_2217 ENOG4105C3M thioredoxin reductase DJ92_2219 ENOG4108S4C acetyltransferase DJ92_2222 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) DJ92_2223 ENOG41086DT Membrane protein of unknown function DJ92_2224 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DJ92_2225 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DJ92_2227 ENOG4105CUB amino acid DJ92_2231 ENOG4105DUM transcriptional regulator, lysR family DJ92_2233 ENOG4108WS4 fmn reductase DJ92_2234 ENOG4105C5H ABC transporter DJ92_2237 ENOG4105CN1 protease DJ92_2238 ENOG4105CRP Part of the ABC transporter FtsEX involved in DJ92_2239 ENOG4105CAK Cell division ATP-binding protein ftsE DJ92_2241 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) DJ92_2244 ENOG4105VEQ Cold shock protein DJ92_2245 ENOG41081UC Inherit from COG: Competence protein DJ92_2248 ENOG4105KVH Transcriptional regulator DJ92_2250 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein DJ92_2251 ENOG4108KGH TRANSCRIPTIONal DJ92_2252 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DJ92_2253 ENOG4105C6Y Udp-glucose 6-dehydrogenase DJ92_2254 ENOG4105ESV Glycosyl transferase, family 4 DJ92_2256 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DJ92_2260 ENOG4105F8D glycoside hydrolase family 4 DJ92_2261 ENOG4105VCP PTS System DJ92_2262 ENOG4105CK1 PTS System DJ92_2266 ENOG4105VCP PTS System DJ92_2268 ENOG4105VZJ PTS System DJ92_2278 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) DJ92_2280 ENOG4105DAA L-lactate DJ92_2281 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) DJ92_2283 ENOG4105E0M Sulfatase DJ92_2288 ENOG4105C94 Transporter DJ92_2289 ENOG41069ER domain protein DJ92_2294 ENOG4105KBK Zinc finger, swim domain protein DJ92_2295 ENOG4105C0D helicase DJ92_2303 ENOG4107RBB ABC transporter, permease DJ92_2304 ENOG4105C19 ABC transporter DJ92_2308 ENOG4105CXY transporter DJ92_2311 ENOG41062D9 Histidine kinase DJ92_2312 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_2313 ENOG4105CMR udp-glucose 4-epimerase DJ92_2315 ENOG4106MCE EamA-like transporter family DJ92_2316 ENOG4108KN0 Choline kinase DJ92_2317 ENOG4105KPE licD family DJ92_2318 ENOG4108KGH TRANSCRIPTIONal DJ92_2319 ENOG4105CMR udp-glucose 4-epimerase DJ92_232 ENOG4105DEG Vwa containing coxe family protein DJ92_2322 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase DJ92_2324 ENOG4105D3Q Sugar transferase DJ92_2327 ENOG4107QQG Dehydrogenase DJ92_2328 ENOG4105VFN O-Antigen polymerase DJ92_2331 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ92_2332 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ92_2333 ENOG4108RB3 Capsular polysaccharide biosynthesis protein DJ92_2334 ENOG4107YJ4 chain length determinant protein DJ92_2335 ENOG4105HTX biosynthesis protein DJ92_2337 ENOG4105BZ1 (ABC) transporter DJ92_234 ENOG4105KKX ATPase associated with various cellular activities aaa_5 DJ92_2343 ENOG4105CAQ asparagine synthetase DJ92_2344 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase DJ92_2346 ENOG4105D3Q Sugar transferase DJ92_2351 ENOG4108UW5 maltose o-acetyltransferase DJ92_2359 ENOG41068W6 Capsular polysaccharide biosynthesis protein DJ92_2360 ENOG4107SJB teichoic acid biosynthesis DJ92_2361 ENOG4108KMV Glycosyl transferase (Group 1 DJ92_2362 ENOG4107QRS glycosyltransferase group 2 family protein DJ92_2363 ENOG4108PQP glycosyl transferase group 1 DJ92_2365 ENOG4107YJ4 chain length determinant protein DJ92_2366 ENOG4105HTX biosynthesis protein DJ92_2367 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DJ92_2368 ENOG4105EY8 ABC transporter DJ92_2370 ENOG4107SJB teichoic acid biosynthesis DJ92_2371 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase DJ92_2373 ENOG4107RZX Teichoic acid biosynthesis protein DJ92_2374 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase DJ92_2376 ENOG4105MT0 Sporulation transcriptional regulator spoiiid DJ92_2377 ENOG4105FRN stage II sporulation protein DJ92_2380 ENOG4108IUW ABC transporter DJ92_2381 ENOG4105CEY Amp-dependent synthetase and ligase DJ92_2385 ENOG4106778 Protein of unknown function (DUF1146) DJ92_2386 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DJ92_2387 ENOG4105C8S subunit m DJ92_2388 ENOG4105D65 subunit l DJ92_2389 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DJ92_2392 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) DJ92_2393 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DJ92_2394 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DJ92_2396 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DJ92_240 ENOG4107STQ Multicopper oxidase DJ92_2400 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) DJ92_2402 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) DJ92_2403 ENOG4107XXH F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DJ92_2404 ENOG4107ZFM Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) DJ92_2406 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) DJ92_2407 ENOG41062M3 atp synthase DJ92_2409 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) DJ92_241 ENOG4107RAQ aminopeptidase DJ92_2411 ENOG4108UIC UPF0340 protein DJ92_2412 ENOG4108YZG isomerase DJ92_2415 ENOG4108VGI doxx family DJ92_2416 ENOG4107XC4 flavin reductase domain protein, FMN-binding DJ92_2419 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DJ92_2421 ENOG4108ZXQ stage ii sporulation protein r DJ92_2422 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DJ92_2426 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DJ92_2427 ENOG4105CBT Fructose-1,6-bisphosphatase DJ92_2428 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DJ92_2435 ENOG4105C1G acyl-Coa dehydrogenase DJ92_2436 ENOG4105C1G acyl-Coa dehydrogenase DJ92_2437 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DJ92_2439 ENOG4105DF6 Fe-S oxidoreductase DJ92_2441 ENOG4105E5J UV damage endonuclease DJ92_2446 ENOG4105BZU Histidine kinase DJ92_2447 ENOG4105KCT ABC transporter DJ92_2448 ENOG4108M15 ABC transporter DJ92_2449 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) DJ92_2450 ENOG4105IIU Aminopeptidase DJ92_2457 ENOG4105CYW agmatinase DJ92_2459 ENOG4105DXB Major Facilitator superfamily DJ92_2460 ENOG4107SWG transcriptional regulator MERR family DJ92_2461 ENOG4108QXE glycerophosphoryl diester phosphodiesterase DJ92_2462 ENOG4105BZ4 penicillin-binding protein DJ92_2463 ENOG4108XFG YwhD family DJ92_2464 ENOG4108Z4T Peptidase M50 DJ92_2465 ENOG41069HH 4-oxalocrotonate tautomerase DJ92_2466 ENOG4105DCI Phosphohydrolase DJ92_2467 ENOG4108MES Periplasmic binding protein DJ92_2468 ENOG4105E0A ABC, transporter DJ92_2469 ENOG4105EHG Permease protein DJ92_2470 ENOG4105DQ5 transport system permease protein DJ92_2472 ENOG4108VCI transcription factor, rsfa family DJ92_2474 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) DJ92_2475 ENOG4108IJ2 phosphate acetyltransferase DJ92_2476 ENOG4107JTW chlorite dismutase DJ92_2478 ENOG4108VKI Cell wall hydrolase DJ92_2480 ENOG4105M08 Membrane DJ92_2482 ENOG4107SVH Potassium channel protein DJ92_2484 ENOG410667J hydrolase DJ92_2485 ENOG4105VCH membrane DJ92_2486 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) DJ92_2487 ENOG4108TU7 Inherit from COG: (ABC) transporter DJ92_2488 ENOG4105CJ1 ABC, transporter DJ92_2489 ENOG41090WU lipolytic protein G-D-S-L family DJ92_2492 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) DJ92_2493 ENOG4105D6E homoserine dehydrogenase DJ92_2494 ENOG4105CVG Homoserine O-transsuccinylase DJ92_2500 ENOG4108Y4K DNA-binding transcriptional activator DJ92_2502 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_2503 ENOG4105BZU Histidine kinase DJ92_2504 ENOG4105DWF phosphomethylpyrimidine kinase DJ92_2506 ENOG4105D22 carbon starvation protein DJ92_2507 ENOG4105DY9 regulatoR DJ92_2508 ENOG41079KZ Major Facilitator Superfamily DJ92_251 ENOG41065RQ ADP-ribosylation crystallin J1 DJ92_2510 ENOG4105BZF Glycosyl transferase (Group 1 DJ92_2512 ENOG4105EN6 Membrane DJ92_2514 ENOG4108S4H thioesterase Superfamily protein DJ92_2516 ENOG4105JEU Glycosyl transferase, family 2 DJ92_2518 ENOG4108IG5 Transcriptional regulator DJ92_2519 ENOG4105C5H ABC transporter DJ92_2522 ENOG4105CKK Glycosyl transferase, family 2 DJ92_2523 ENOG41067SE Tetr family transcriptional regulator DJ92_2525 ENOG4105E0X reductase DJ92_2526 ENOG4106F5Q Membrane DJ92_2529 ENOG4105DY9 regulatoR DJ92_2530 ENOG4108HRK Histidine kinase DJ92_2534 ENOG4105IW1 AmiS UreI transporter DJ92_2536 ENOG4108UT2 hemolysin iii DJ92_2541 ENOG4105C1J atp-dependent rna helicase DJ92_2544 ENOG4107QJT sodium dicarboxylate symporter DJ92_2545 ENOG4108MRH transcriptional regulatory protein DJ92_2546 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism DJ92_2547 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DJ92_2548 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) DJ92_2552 ENOG4105C0H protease DJ92_2553 ENOG4105Q2H domain protein DJ92_2556 ENOG4105BZU Histidine kinase DJ92_2557 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_2562 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DJ92_2563 ENOG4105CDU Replicative dna helicase DJ92_2565 ENOG4105BZR domain protein DJ92_2566 ENOG4108XMW Membrane DJ92_2568 ENOG4108UUM single-stranded DNA-binding protein DJ92_2569 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) DJ92_2570 ENOG4105C3G gtp-binding protein DJ92_2571 ENOG4105VDK protein, conserved in bacteria DJ92_2572 ENOG4105D8X mechanosensitive ion channel DJ92_2573 ENOG4108ZDA Sporulation protein YyaC DJ92_2574 ENOG4105FA0 parb-like partition protein DJ92_2575 ENOG4107QJE Chromosome Partitioning Protein DJ92_2578 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) DJ92_2579 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) DJ92_2581 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DJ92_2582 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) DJ92_2584 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) DJ92_2585 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DJ92_2586 ENOG410848D S4 domain protein YaaA DJ92_2589 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ92_2597 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DJ92_2604 ENOG4105ZMH deoxynucleoside kinase DJ92_2606 ENOG4105GTG Isochorismatase DJ92_2607 ENOG4108Z6B deaminase DJ92_2608 ENOG4105C6E dna polymerase iii DJ92_2610 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) DJ92_2620 ENOG4105CXN decarboxylase DJ92_2622 ENOG4105FA2 dna polymerase iii DJ92_2623 ENOG4105MA4 psp1 domain protein DJ92_2624 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) DJ92_2625 ENOG41060K3 Methyltransferase DJ92_2627 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DJ92_2628 ENOG4105KRN Transcriptional regulator, abrb family DJ92_2629 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DJ92_2630 ENOG4105F8V Hydrolase, tatD family DJ92_2631 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) DJ92_2632 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DJ92_2633 ENOG4105XFA sporulation peptidase YabG DJ92_2634 ENOG4105W42 Veg protein DJ92_2636 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) DJ92_2637 ENOG4105DFT pur operon repressor DJ92_2638 ENOG4105KME endoribonuclease L-psp DJ92_2640 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) DJ92_2641 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DJ92_2644 ENOG4108JA2 transcriptioN-repair coupling factor DJ92_2645 ENOG4108M14 stage v sporulation protein t DJ92_2647 ENOG4108IY2 MazG family DJ92_2648 ENOG41082I2 s4 domain protein DJ92_2649 ENOG4105VYY sporulation protein yabp DJ92_2652 ENOG41060GV RNA binding s1 domain protein DJ92_2657 ENOG4108UGV hypoxanthine phosphoribosyltransferase DJ92_2658 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DJ92_2661 ENOG4105C6T cysteine synthase DJ92_2662 ENOG4105CRQ synthase (Component I) DJ92_2663 ENOG4105DDQ anthranilate synthase DJ92_2664 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 DJ92_2665 ENOG4105EEI dihydropteroate synthase DJ92_2666 ENOG4105KRF dihydroneopterin aldolase DJ92_2667 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DJ92_2669 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DJ92_2677 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ92_2687 ENOG4108Z0C Uvrb UvrC protein DJ92_2690 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DJ92_2692 ENOG4105CTP PilT protein domain protein DJ92_2693 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) DJ92_2696 ENOG4105D7W serine acetyltransferase DJ92_2699 ENOG4105C2N RNA methyltransferase TrmH family group 3 DJ92_2700 ENOG4105M0M Tetracycline resistance protein DJ92_2701 ENOG4105QIV RNA polymerase DJ92_2703 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DJ92_2706 ENOG4108VZM 50s ribosomal protein L10 DJ92_2707 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) DJ92_2708 ENOG4107Y49 methyltransferase DJ92_2711 ENOG4105XPM ribosomal protein DJ92_2714 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) DJ92_2715 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DJ92_2718 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) DJ92_2726 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal DJ92_2728 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) DJ92_273 ENOG41065RQ ADP-ribosylation crystallin J1 DJ92_2732 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) DJ92_2737 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DJ92_2738 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) DJ92_2739 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DJ92_2741 ENOG41067V7 50S ribosomal protein L36 DJ92_2744 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DJ92_2747 ENOG4108JJB ABC transporter DJ92_2748 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) DJ92_2754 ENOG4105D1F ATP-binding protein DJ92_2757 ENOG4108NMV polysaccharide deacetylase DJ92_2776 ENOG4105C8B TIGR00159 family DJ92_2777 ENOG4107U5W ybbr family DJ92_2783 ENOG4105FTQ Dna gyrase DJ92_2786 ENOG4105C2C drug resistance transporter, Bcr CflA DJ92_2791 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ92_2794 ENOG4105E0C molybdate abc transporter DJ92_2795 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DJ92_2796 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family DJ92_2799 ENOG4105F6E Acyl-transferase DJ92_28 ENOG4107VMI polysaccharide deacetylase DJ92_2802 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DJ92_2803 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ92_2804 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DJ92_2805 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ92_2806 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit DJ92_2807 ENOG4108IFG nitrite reductase, (NAD(P)H) DJ92_2810 ENOG4108RE7 deoxyribonuclease DJ92_2816 ENOG4105C5H ABC transporter DJ92_2817 ENOG4105BZU Histidine kinase DJ92_2818 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_2819 ENOG4105CJ1 ABC, transporter DJ92_2820 ENOG41090VJ ABC-2 type transporter DJ92_2821 ENOG4108KYE ABC-2 type transporter DJ92_2823 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein DJ92_2826 ENOG4105C3U ABC transporter DJ92_2827 ENOG4108JQ7 (ABC) transporter DJ92_2828 ENOG410667J hydrolase DJ92_2834 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase DJ92_2835 ENOG4105ERH Fumarylacetoacetate hydrolase DJ92_2837 ENOG4105CUB amino acid DJ92_2838 ENOG4108SC4 )-transporter DJ92_2839 ENOG4105CPF Cell wall formation (By similarity) DJ92_284 ENOG4108ISG Major Facilitator DJ92_2840 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) DJ92_2845 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein DJ92_2848 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) DJ92_2860 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ92_287 ENOG4107MII Sugar-specific transcriptional regulator TrmB DJ92_2871 ENOG4105K8N protein family UPF0079, ATPase DJ92_2872 ENOG41072GX Peptidase M22 Glycoprotease DJ92_2873 ENOG410801F ribosomal-protein-alanine acetyltransferase DJ92_2874 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DJ92_2875 ENOG4105C5H ABC transporter DJ92_2878 ENOG4108TYN CAAX amino terminal protease family protein DJ92_288 ENOG4105CZM Major Facilitator DJ92_2882 ENOG4105C7N Xanthine uracil vitamin C permease DJ92_2884 ENOG4105BZU Histidine kinase DJ92_2892 ENOG4105SX7 Transporter DJ92_29 ENOG4105E0M Sulfatase DJ92_2902 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_2907 ENOG4105SX7 Transporter DJ92_291 ENOG4105DYS nad(p)h dehydrogenase (quinone) DJ92_2911 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DJ92_2912 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DJ92_2913 ENOG4105C83 adenylosuccinate lyase DJ92_2914 ENOG4105C8V SAICAR synthetase DJ92_2915 ENOG4105VR9 phosphoribosylformylglycinamidine synthase DJ92_2916 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I DJ92_2917 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii DJ92_2920 ENOG4108V3E phosphoribosylglycinamide formyltransferase DJ92_2921 ENOG4105DC1 bifunctional purine biosynthesis protein purh DJ92_2922 ENOG4105C12 Phosphoribosylglycinamide synthetase DJ92_2923 ENOG4108JUB Transcriptional regulator DJ92_2924 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DJ92_2925 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DJ92_2926 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DJ92_2927 ENOG4108IQI permease DJ92_2933 ENOG4105C4R Atp-dependent dna helicase DJ92_2937 ENOG4105C26 Dehydrogenase DJ92_2939 ENOG4108W2Y isochorismatase DJ92_2943 ENOG410834F Transcriptional regulator DJ92_2944 ENOG4107I77 yiaA/B two helix domain DJ92_2948 ENOG4105CBD Diacylglycerol kinase DJ92_2949 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DJ92_2950 ENOG4108JPW Aminotransferase DJ92_2953 ENOG4105C26 Dehydrogenase DJ92_2959 ENOG4105D9N nucleoside DJ92_296 ENOG4108JJB ABC transporter DJ92_2960 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) DJ92_2962 ENOG4108W15 Protein of unknown function (DUF1456) DJ92_2965 ENOG4105DTQ mandelate racemase muconate lactonizing DJ92_2968 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) DJ92_2969 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) DJ92_2970 ENOG4105E98 transcriptional regulator DeoR family DJ92_2971 ENOG4107W7X Aldolase DJ92_2972 ENOG4105EHG Permease protein DJ92_2973 ENOG4105DQ5 transport system permease protein DJ92_2974 ENOG4108V5C ABC transporter DJ92_2975 ENOG4105CAY ferredoxin--nadp reductase DJ92_2978 ENOG4106UIA DJ92_2979 ENOG4106UIA DJ92_2982 ENOG4105BZU Histidine kinase DJ92_2985 ENOG410756H nucleotidyltransferase DJ92_2988 ENOG4105E5Q amino acid AbC transporter DJ92_2989 ENOG4105EAB amino acid AbC transporter DJ92_2990 ENOG4105CDA abc transporter atp-binding protein DJ92_2991 ENOG4105DNP FAD linked oxidase domain protein DJ92_2994 ENOG4105DBV ornithine carbamoyltransferase DJ92_2996 ENOG4105C5B carbamate kinase DJ92_2997 ENOG4108W63 CRP FNR family transcriptional regulator DJ92_30 ENOG4105C5H ABC transporter DJ92_3000 ENOG4105CI1 PTS System DJ92_3004 ENOG4105DHS permease protein DJ92_3005 ENOG4105CM4 permease protein DJ92_3006 ENOG4108IPW abc transporter atp-binding protein DJ92_3010 ENOG4105C7B Threonine dehydratase DJ92_3011 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter DJ92_3014 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DJ92_3017 ENOG4105C5H ABC transporter DJ92_3019 ENOG4105D01 (LipO)protein DJ92_302 ENOG4108Z66 YbaK ebsC protein DJ92_3020 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DJ92_3021 ENOG4108UMI ABC transporter, permease DJ92_3025 ENOG41062JF Transcriptional regulator DJ92_3028 ENOG4105DEU major facilitator superfamily DJ92_3036 ENOG4108N0M stress protein DJ92_3037 ENOG4106FN3 tellurium resistance protein DJ92_3038 ENOG4106FN3 tellurium resistance protein DJ92_3039 ENOG4107TS3 membrane protein, TerC DJ92_3040 ENOG4108TTB tellurium resistance protein DJ92_3043 ENOG41068PA UPF0435 protein DJ92_3044 ENOG4105KJF protein tyrosine phosphatase DJ92_3046 ENOG4107U9T Pfam:Ribonuclease_BN DJ92_3048 ENOG4105C59 p-type ATPase DJ92_3049 ENOG4108IPJ Membrane DJ92_3055 ENOG4107ZTW SNARE associated Golgi DJ92_3058 ENOG410606W general stress protein DJ92_3059 ENOG4105UPD Calcium Proton DJ92_306 ENOG4108PSK reductase DJ92_3071 ENOG4108JUB Transcriptional regulator DJ92_3073 ENOG4108IQI permease DJ92_308 ENOG4105CJ1 ABC, transporter DJ92_3080 ENOG4105CSV Glutaminase DJ92_3082 ENOG4108A04 Beta-lactamase DJ92_3083 ENOG4107ZXU DSBA oxidoreductase DJ92_3085 ENOG4105F1A Pyruvate formate-lyase DJ92_3086 ENOG4108QBV Monogalactosyldiacylglycerol synthase DJ92_3089 ENOG4105CI2 imidazolone-5-propionate hydrolase DJ92_3090 ENOG4105ECP epimerase DJ92_3091 ENOG410902V Modulates RecA activity (By similarity) DJ92_3096 ENOG41067AE Membrane-bound metal-dependent hydrolase DJ92_3097 ENOG4105CEN a g-specific adenine glycosylase DJ92_3098 ENOG41088CQ domain protein DJ92_3099 ENOG4106BXE DJ92_3102 ENOG4105EVI UPF0374 protein DJ92_3103 ENOG4107NBY Membrane DJ92_3104 ENOG4105BZ1 (ABC) transporter DJ92_3105 ENOG4105CBC glutamate synthase DJ92_3107 ENOG4108IUW ABC transporter DJ92_311 ENOG4105PAD Hydrolase DJ92_3111 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ92_3112 ENOG4105G5W regulator Fur family DJ92_3136 ENOG4108JQC penicillin-binding protein 1A DJ92_3137 ENOG4107ZQN disulfide bond DJ92_3139 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DJ92_3141 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DJ92_3143 ENOG4105CYN Serine protein kinase DJ92_3144 ENOG4106AKX UPF0229 protein DJ92_3146 ENOG4105DZ6 Band 7 protein DJ92_3147 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_3148 ENOG4105BZU Histidine kinase DJ92_3153 ENOG4105EU9 DJ92_3157 ENOG4108V9W transcriptional regulatory protein DJ92_3158 ENOG4105D4T Citrate transporter DJ92_3163 ENOG4105DA5 (ABC) transporter DJ92_3168 ENOG4108NNI Beta-lactamase domain-containing protein DJ92_3169 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase DJ92_3171 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DJ92_3172 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DJ92_3173 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component DJ92_3174 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component DJ92_3176 ENOG4108STX response regulator DJ92_3177 ENOG4105US7 Histidine kinase DJ92_3181 ENOG4108MRH transcriptional regulatory protein DJ92_3183 ENOG4105C6K Malic enzyme DJ92_3185 ENOG4108UZ3 Transporter DJ92_3186 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ92_3188 ENOG4105BZU Histidine kinase DJ92_3189 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_3192 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DJ92_3193 ENOG4108JB9 formate dehydrogenase DJ92_3197 ENOG4105CUB amino acid DJ92_3200 ENOG4105C59 p-type ATPase DJ92_3201 ENOG4105DAP Nicotinate phosphoribosyltransferase DJ92_3206 ENOG4105VPX protein, conserved in bacteria DJ92_3211 ENOG41073R8 VanW family DJ92_3212 ENOG4108KGH TRANSCRIPTIONal DJ92_3213 ENOG4105D9N nucleoside DJ92_3214 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase DJ92_3215 ENOG4105C37 (CBS) domain DJ92_3216 ENOG4108IJ0 Aspartate ammonia-lyase DJ92_3217 ENOG4105DAA L-lactate DJ92_3220 ENOG4105DUX Transporter DJ92_3221 ENOG4108MES Periplasmic binding protein DJ92_3222 ENOG4105DQ5 transport system permease protein DJ92_3223 ENOG4108IHU transport system permease protein DJ92_3224 ENOG4105E0A ABC, transporter DJ92_3225 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) DJ92_3229 ENOG4107T89 von Willebrand factor, type A DJ92_3230 ENOG4105GMT ATPase associated with various cellular activities aaa_5 DJ92_3231 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ92_3235 ENOG4105D5Q Arginine ornithine antiporter DJ92_3236 ENOG4107414 GntR family transcriptional regulator DJ92_3237 ENOG4105C5Y PTS System DJ92_3238 ENOG4105CG3 alpha amylase, catalytic region DJ92_3239 ENOG4105CRN Aminoglycoside phosphotransferase DJ92_324 ENOG4105EV4 Multidrug resistance protein mdtH DJ92_3240 ENOG4105BZG amino acid carrier protein DJ92_3241 ENOG4105CDA abc transporter atp-binding protein DJ92_3242 ENOG4105CT1 (ABC) transporter DJ92_3243 ENOG4105EAD ABC transporter DJ92_3244 ENOG4105DRP amino acid AbC transporter DJ92_3245 ENOG4108IQI permease DJ92_3247 ENOG4105BZU Histidine kinase DJ92_3250 ENOG4107YZX Universal stress protein DJ92_3252 ENOG4105CXY transporter DJ92_3253 ENOG41067TZ transcriptional regulator, MarR family DJ92_3254 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ92_3255 ENOG4105ETE Transcriptional regulator (LacI family DJ92_3256 ENOG4108RVA ribokinase DJ92_3258 ENOG4105C2J ABC transporter DJ92_3259 ENOG4105CNN ABC, transporter DJ92_3260 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator DJ92_3261 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DJ92_3263 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ92_3266 ENOG4107SVH Potassium channel protein DJ92_3269 ENOG4105QE3 oxidoreductase DJ92_3272 ENOG41069ER domain protein DJ92_3273 ENOG4105VZ8 Transcriptional regulator DJ92_3274 ENOG4107D63 DJ92_3275 ENOG4108NS2 receptor DJ92_3277 ENOG4105DUX Transporter DJ92_3283 ENOG4105C85 amino acid DJ92_3284 ENOG4105C7N Xanthine uracil vitamin C permease DJ92_3287 ENOG4105MA6 gCN5-related N-acetyltransferase DJ92_329 ENOG4105DWT malate dehydrogenase (quinone) DJ92_3291 ENOG4105CCU oxidase (Subunit III) DJ92_3293 ENOG4105E2S oxidase) subunit II DJ92_3299 ENOG4108NHD germination protein DJ92_3300 ENOG4105CE1 Ferrous iron transport protein b DJ92_3301 ENOG4105CE1 Ferrous iron transport protein b DJ92_3302 ENOG4105CE1 Ferrous iron transport protein b DJ92_3303 ENOG4105CVA phosphate DJ92_3304 ENOG4105C8U phosphate abc transporter DJ92_3305 ENOG4105E2Z phosphate ABC transporter (Permease DJ92_3315 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DJ92_333 ENOG4105C37 (CBS) domain DJ92_3332 ENOG41080XQ Signal transduction protein with cbs domains DJ92_3336 ENOG4105ETU transcriptional activator (TenA DJ92_3338 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DJ92_3340 ENOG4108VEU Thiamine monophosphate synthase DJ92_3341 ENOG41080HI glycine oxidase DJ92_3344 ENOG4105D06 uba thif-type nad fad binding protein DJ92_3345 ENOG4105DWF phosphomethylpyrimidine kinase DJ92_3354 ENOG4108INS Transcriptional regulator DJ92_3357 ENOG4105C7N Xanthine uracil vitamin C permease DJ92_3359 ENOG4108VZI ErfK ybiS ycfS ynhG family protein DJ92_3361 ENOG4105K63 Thioredoxin DJ92_3363 ENOG4108RCF TRANSCRIPTIONal DJ92_3366 ENOG4108B31 Spore germination protein DJ92_3370 ENOG4107Y03 Nitroreductase DJ92_3371 ENOG4105ED1 spovr family DJ92_3373 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase DJ92_3374 ENOG4105XTG Pfam:DUF156 DJ92_3375 ENOG4107TPS domain protein DJ92_3376 ENOG4105VFE sira family DJ92_3377 ENOG41085GJ domain protein DJ92_3378 ENOG41085GJ domain protein DJ92_3379 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase DJ92_338 ENOG4105DDN Pentapeptide repeat-containing protein DJ92_3380 ENOG41087NI Sulfite exporter TauE/SafE DJ92_3382 ENOG4108KGH TRANSCRIPTIONal DJ92_3385 ENOG4105CZM Major Facilitator DJ92_3389 ENOG4107RBB ABC transporter, permease DJ92_339 ENOG4105DND Transcriptional regulator DJ92_3390 ENOG4105C19 ABC transporter DJ92_3396 ENOG4105WEF catalase DJ92_3403 ENOG4107T5V SNARE associated Golgi DJ92_3406 ENOG4105CUB amino acid DJ92_3407 ENOG4107RWR Sodium hydrogen exchanger DJ92_3409 ENOG4106KNT transcriptional regulator DJ92_341 ENOG4105XDF Protein of unknown function (DUF1272) DJ92_3410 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate DJ92_3417 ENOG4108PCN EamA-like transporter family DJ92_3418 ENOG4108YXU transcriptional regulator AsnC family DJ92_3420 ENOG4105CHR reductase DJ92_3423 ENOG4105NF4 modulator of drug activity DJ92_3424 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DJ92_3425 ENOG4105E5W Transporter DJ92_3430 ENOG4108ZJ4 polysaccharide deacetylase DJ92_3432 ENOG4105D5Q Arginine ornithine antiporter DJ92_3433 ENOG4105C26 Dehydrogenase DJ92_3435 ENOG4105BZ1 (ABC) transporter DJ92_3436 ENOG4105BZ1 (ABC) transporter DJ92_3438 ENOG4105DRP amino acid AbC transporter DJ92_3439 ENOG4105CDA abc transporter atp-binding protein DJ92_3442 ENOG410839P DJ92_3443 ENOG4106MP8 UPF0754 membrane protein DJ92_3444 ENOG4105WZB UPF0342 protein DJ92_3446 ENOG4107FQX Alpha-acetolactate decarboxylase DJ92_3449 ENOG4105D4P Coproporphyrinogen iii oxidase DJ92_3453 ENOG4105CHH sulfate transporter DJ92_3455 ENOG4105CGU Enoyl-CoA hydratase DJ92_3458 ENOG4105DER m42 family DJ92_3461 ENOG4105E1K spore germination protein DJ92_3464 ENOG4105C85 amino acid DJ92_3465 ENOG4108JPW Aminotransferase DJ92_3471 ENOG4105D5U fad dependent oxidoreductase DJ92_3476 ENOG4105CXY transporter DJ92_3484 ENOG4108JUB Transcriptional regulator DJ92_3486 ENOG4105CSH Transporter DJ92_3488 ENOG4108MRH transcriptional regulatory protein DJ92_349 ENOG4105JAB phenazine biosynthesis protein, phzf family DJ92_3506 ENOG4105CFI type iii restriction protein res subunit DJ92_3507 ENOG4105CY2 Citrate transporter DJ92_3510 ENOG4105CDU Replicative dna helicase DJ92_3517 ENOG4105CMR udp-glucose 4-epimerase DJ92_3519 ENOG4108QV3 biosynthesis protein DJ92_3521 ENOG4108XW0 May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF DJ92_3525 ENOG4105IQ5 FAD linked oxidase domain protein DJ92_3526 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DJ92_3528 ENOG4105G6Z alkaline phosphatase DJ92_3534 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DJ92_3535 ENOG4108K8K Transcriptional regulator DJ92_3536 ENOG4107VMI polysaccharide deacetylase DJ92_3539 ENOG41073R8 VanW family DJ92_354 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein DJ92_3545 ENOG4105BZ1 (ABC) transporter DJ92_3547 ENOG4105BZU Histidine kinase DJ92_3548 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_355 ENOG4105KVH Transcriptional regulator DJ92_3552 ENOG4106A3M Cytochrome p-450 DJ92_3557 ENOG4106PZP Bacillus haemolytic enterotoxin (HBL) DJ92_3561 ENOG41067TZ transcriptional regulator, MarR family DJ92_3564 ENOG4107ZXU DSBA oxidoreductase DJ92_3573 ENOG4105CUB amino acid DJ92_3574 ENOG4105C7B Threonine dehydratase DJ92_3576 ENOG4107R7I amino acid DJ92_3578 ENOG4105EJQ L-serine dehydratase DJ92_3579 ENOG4105C44 Serine transporter DJ92_358 ENOG4107TXC Transcriptional regulator DJ92_3582 ENOG4107T32 3-phytase (EC 3.1.3.8) DJ92_3583 ENOG4108RWI nicotinamidase DJ92_3584 ENOG4105XDF Protein of unknown function (DUF1272) DJ92_359 ENOG4105DJB Major Facilitator Superfamily DJ92_3599 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_36 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase DJ92_360 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) DJ92_3601 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ92_3602 ENOG4107VMI polysaccharide deacetylase DJ92_3604 ENOG4105BZU Histidine kinase DJ92_361 ENOG4107QR9 Iron-sulfur cluster binding protein DJ92_3610 ENOG4105DRS transport system, permease DJ92_3625 ENOG4105DQ6 Transposase DJ92_3629 ENOG4105CMT Dihydroxyacetone kinase DJ92_363 ENOG4106P55 Transcriptional regulator DJ92_3631 ENOG4105CMT Dihydroxyacetone kinase DJ92_3635 ENOG4107WD8 ABC transporter, permease DJ92_364 ENOG410751J DJ92_3641 ENOG4105BZU Histidine kinase DJ92_3642 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_3644 ENOG4108PCX Major Facilitator DJ92_3646 ENOG41073TP transcriptional regulator DJ92_3652 ENOG4107STQ Multicopper oxidase DJ92_3663 ENOG4107VRP DNA repair exonuclease DJ92_3664 ENOG4106D4I domain protein DJ92_3665 ENOG4105EQI Metal Dependent Phosphohydrolase DJ92_3668 ENOG4107JM4 Tetratricopeptide repeat DJ92_3670 ENOG4108MUZ hydrolase DJ92_3673 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator DJ92_3675 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) DJ92_3677 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DJ92_3678 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DJ92_3684 ENOG4105K59 histidine triad (HIT) protein DJ92_3688 ENOG4105E09 nadh pyrophosphatase DJ92_3693 ENOG410905X membrane-flanked domain protein DJ92_3694 ENOG4105CKV Membrane DJ92_3696 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase DJ92_3698 ENOG4105CUB amino acid DJ92_370 ENOG4105ED2 Beta-lactamase DJ92_3705 ENOG410905X membrane-flanked domain protein DJ92_3706 ENOG4105CKV Membrane DJ92_3708 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation DJ92_3709 ENOG4105BZ4 penicillin-binding protein DJ92_3710 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) DJ92_3712 ENOG4105C1Q protoporphyrinogen oxidase DJ92_3714 ENOG4105MDS 4-oxalocrotonate tautomerase DJ92_3715 ENOG4107V2S Transcriptional regulator DJ92_3716 ENOG4105EGI Transcriptional regulator DJ92_3721 ENOG4105ECB domain protein DJ92_3724 ENOG4105D29 Helix-turn-helix type 11 domain protein DJ92_3726 ENOG4106AXD DJ92_3727 ENOG4108RQ5 Beta-lactamase domain-containing protein DJ92_3728 ENOG4105DF9 Lipoate-protein, ligase DJ92_3729 ENOG4105CEY Amp-dependent synthetase and ligase DJ92_373 ENOG4105H3G oxidoreductase DJ92_3731 ENOG4107RN3 metallophosphoesterase DJ92_3733 ENOG41086D8 Transcriptional regulator DJ92_3735 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ92_3740 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 DJ92_3745 ENOG4107QP3 malate synthase g DJ92_3749 ENOG4105XVF Competence transcription factor DJ92_3751 ENOG4105BZU Histidine kinase DJ92_3764 ENOG4105ERH Fumarylacetoacetate hydrolase DJ92_3769 ENOG4105CAQ asparagine synthetase DJ92_3771 ENOG4105F0V Cell wall hydrolase DJ92_3773 ENOG4105CH6 catalase DJ92_3774 ENOG4105BZU Histidine kinase DJ92_3778 ENOG4105QNR S1 RNA binding domain protein DJ92_3779 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DJ92_3781 ENOG4107AYK membrAne DJ92_3782 ENOG41073B9 DJ92_3784 ENOG4108KP7 hydrolase DJ92_3786 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DJ92_3791 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DJ92_3792 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DJ92_3795 ENOG4105C31 Tryptophanyl-tRNA synthetase DJ92_3798 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DJ92_3799 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DJ92_380 ENOG4105C8Y Acetylornithine aminotransferase DJ92_3801 ENOG4108JQ7 (ABC) transporter DJ92_3802 ENOG4105UQX Mate efflux family protein DJ92_3806 ENOG4108ZCF integral membrane protein DJ92_3808 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ92_3810 ENOG4105DPN Oligoendopeptidase f DJ92_3813 ENOG4108Z18 K06886 hemoglobin DJ92_3814 ENOG4105MIX Adenylate cyclase DJ92_3818 ENOG4105EMS pseudouridine synthase DJ92_3819 ENOG4107S1Q Phosphatase DJ92_3823 ENOG4105D2T synthase DJ92_3826 ENOG4107TY6 Acylneuraminate cytidylyltransferase DJ92_3827 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase DJ92_3828 ENOG4105C5E polysaccharide biosynthesis protein DJ92_3829 ENOG4105K64 Glycosyl transferase, family 2 DJ92_3831 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DJ92_3839 ENOG4105C1B dTDP-glucose 4-6-dehydratase DJ92_384 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DJ92_3843 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DJ92_3844 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase DJ92_3846 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase DJ92_385 ENOG4105KRN Transcriptional regulator, abrb family DJ92_3861 ENOG4105CK7 Sodium proline symporter DJ92_3862 ENOG4105CRQ synthase (Component I) DJ92_3863 ENOG4105DDQ anthranilate synthase DJ92_3864 ENOG4108I0Q anthranilate phosphoribosyltransferase DJ92_3866 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase DJ92_3867 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DJ92_3868 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) DJ92_387 ENOG410890F Dynamin family DJ92_3885 ENOG4105C7S Dehydrogenase DJ92_3886 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 DJ92_3890 ENOG41069ER domain protein DJ92_3892 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) DJ92_3893 ENOG4105C4X radical SAM domain protein DJ92_3897 ENOG4108IBT Inherit from COG: transposase DJ92_3898 ENOG4108IBT Inherit from COG: transposase DJ92_39 ENOG4105BZC d-serine deaminase DJ92_3919 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DJ92_3923 ENOG4105DZ1 carboxypeptidase DJ92_3924 ENOG4105VFR signal peptidase DJ92_3932 ENOG4105C26 Dehydrogenase DJ92_3933 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DJ92_3934 ENOG4105F38 ABC transporter, permease DJ92_3935 ENOG4105D38 putrescine abc transporter DJ92_3936 ENOG4107RUE extracellular solute-binding protein family 1 DJ92_3937 ENOG4105YVM Phosphoesterase, PA-phosphatase related DJ92_3938 ENOG4105EYF MMPL domain protein DJ92_394 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ92_3940 ENOG4108YBP pseudouridine synthase DJ92_3942 ENOG4105K4I Scp-like extracellular DJ92_3943 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DJ92_3944 ENOG4105CQB FAD linked oxidase domain protein DJ92_3947 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_3948 ENOG4105BZU Histidine kinase DJ92_3949 ENOG4105JXH GntR family transcriptional regulator DJ92_3950 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DJ92_3953 ENOG4106A3R peptidase DJ92_3955 ENOG4108QTI )-transporter DJ92_3956 ENOG4107TS3 membrane protein, TerC DJ92_3957 ENOG4105CZN Potassium uptake protein DJ92_3958 ENOG410681C small acid-soluble spore protein DJ92_3959 ENOG4108Z7G MaoC domain protein dehydratase DJ92_3963 ENOG4105CHR reductase DJ92_3971 ENOG4105E98 transcriptional regulator DeoR family DJ92_3972 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) DJ92_3974 ENOG4105PXI polysaccharide deacetylase DJ92_3976 ENOG4105BZU Histidine kinase DJ92_3977 ENOG41090MY MarR family Transcriptional regulator DJ92_3979 ENOG4106DF1 DJ92_3981 ENOG4105BZU Histidine kinase DJ92_3982 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) DJ92_3983 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase DJ92_3984 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DJ92_3985 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) DJ92_3989 ENOG4108R6G acetyltransferase DJ92_3992 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) DJ92_3993 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ92_3995 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ92_3996 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DJ92_3997 ENOG4105CUB amino acid DJ92_3998 ENOG4105D82 Glutamate dehydrogenase DJ92_4001 ENOG4108JUB Transcriptional regulator DJ92_4002 ENOG4105C26 Dehydrogenase DJ92_4003 ENOG4105C8Y Acetylornithine aminotransferase DJ92_4004 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DJ92_4005 ENOG4105C1G acyl-Coa dehydrogenase DJ92_4006 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family DJ92_4007 ENOG4105CZV ABC transporter DJ92_4009 ENOG4105CJ1 ABC, transporter DJ92_4018 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DJ92_4019 ENOG4105EA8 2-Nitropropane dioxygenase DJ92_4020 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DJ92_4022 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DJ92_4027 ENOG4105NQC Flavodoxin DJ92_4034 ENOG4107QMU Mate efflux family protein DJ92_4035 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DJ92_4040 ENOG4105CZN Potassium uptake protein DJ92_4042 ENOG4105KBJ sporulation protein ytfj DJ92_4046 ENOG4105CM2 brancheD-chain amino acid aminotransferase DJ92_4047 ENOG4105C7K acetolactate synthase DJ92_4048 ENOG4108ZP8 Acetolactate synthase small subunit DJ92_4049 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DJ92_405 ENOG4108Z6B deaminase DJ92_4050 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DJ92_4056 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DJ92_4057 ENOG4105ECC imidazole-glycerol-phosphate dehydratase DJ92_406 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) DJ92_4062 ENOG4105KPZ phosphoribosyl-atp pyrophosphatase DJ92_4063 ENOG4107RVV histidinol phosphate phosphatase, hisj family DJ92_4066 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DJ92_4067 ENOG4105E0M Sulfatase DJ92_4069 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DJ92_4073 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) DJ92_4074 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DJ92_4076 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DJ92_4077 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein DJ92_4079 ENOG4105C8J )-transporter DJ92_4084 ENOG4105DFD Na H antiporter DJ92_4088 ENOG4105ENE Histidine kinase DJ92_4089 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_4094 ENOG4105F2W methyltransferase DJ92_4101 ENOG4105CJ3 phosphate transporter DJ92_4102 ENOG4107GRR phosphate transport regulator DJ92_4103 ENOG4105BZ4 penicillin-binding protein DJ92_4105 ENOG4105BZU Histidine kinase DJ92_4106 ENOG4105I3N Conserved Protein DJ92_4107 ENOG4105D7V transposase DJ92_4110 ENOG4105BZU Histidine kinase DJ92_4116 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DJ92_4117 ENOG4105DZ1 carboxypeptidase DJ92_4118 ENOG4108JIC nucleoside recognition domain protein DJ92_4120 ENOG4105FE9 pseudouridine synthase DJ92_4122 ENOG4107TWT Cytochrome c biogenesis protein DJ92_4123 ENOG4105CRE cytochrome C DJ92_4124 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_4125 ENOG4105BZU Histidine kinase DJ92_4126 ENOG4108WBT adenosyltransferase DJ92_4127 ENOG41063SB peptidase DJ92_4129 ENOG4108SAX Membrane DJ92_4131 ENOG4105T7X DJ92_4132 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ92_4133 ENOG4105I7S Abortive infection protein DJ92_4135 ENOG4107RGJ metallophosphoesterase DJ92_4136 ENOG4107X2D transcriptional regulator, merr family DJ92_4137 ENOG4108S6Z Negative regulator of genetic competence DJ92_414 ENOG4105E7U AraC family transcriptional regulator DJ92_4141 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase DJ92_4142 ENOG4107RB3 L-asparaginase DJ92_4148 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_4151 ENOG4105S2F DJ92_4152 ENOG41065D1 DJ92_4158 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) DJ92_4161 ENOG4105XXQ heptaprenyl diphosphate synthase component I DJ92_4162 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DJ92_4163 ENOG4105EAH synthase DJ92_4165 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase DJ92_4169 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase DJ92_4170 ENOG41068YB TPR repeat-containing protein DJ92_4173 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) DJ92_4174 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DJ92_418 ENOG4105C19 ABC transporter DJ92_4181 ENOG4108JYZ YitT family DJ92_4182 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase DJ92_4183 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) DJ92_4185 ENOG4105FJR Lmbe family DJ92_4186 ENOG4105CPK Glycosyl transferase (Group 1 DJ92_4187 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate DJ92_4192 ENOG4105DVT helicase DJ92_4193 ENOG4105YAC DJ92_4197 ENOG4105CSM endonuclease III DJ92_4199 ENOG4105BZ4 penicillin-binding protein DJ92_420 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ92_4210 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) DJ92_4212 ENOG4105DVT helicase DJ92_4213 ENOG4105CTD carboxy-peptidase DJ92_4216 ENOG4107RQ2 Cytochrome c oxidase, subunit I DJ92_4217 ENOG4105NAA Cytochrome C oxidase, subunit II DJ92_4219 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DJ92_4221 ENOG4105C2W permease DJ92_4223 ENOG410890F Dynamin family DJ92_4225 ENOG4108W0I acetyltransferase DJ92_4227 ENOG4105KHC sulfurtransferase DJ92_4236 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DJ92_4237 ENOG4108SZE gCN5-related N-acetyltransferase DJ92_4240 ENOG4108PCN EamA-like transporter family DJ92_4241 ENOG41081VK Ribonuclease DJ92_425 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DJ92_4255 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ92_4256 ENOG4107RWR Sodium hydrogen exchanger DJ92_4257 ENOG4108Z5V transcriptional regulator, merr family DJ92_4259 ENOG4105H67 Protein of unknown function (DUF421) DJ92_4260 ENOG41080C8 DUF218 domain DJ92_4266 ENOG4108IUW ABC transporter DJ92_427 ENOG4108TIT dATP pyrophosphohydrolase DJ92_4275 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DJ92_4280 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) DJ92_4281 ENOG4105KAC Antibiotic biosynthesis monooxygenase DJ92_4287 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr DJ92_4291 ENOG4105CVJ phosphoglycerate mutase DJ92_4295 ENOG4105K56 Transcriptional regulator DJ92_4302 ENOG4105DRR Transcriptional regulator, GntR family DJ92_4303 ENOG4108UZ3 Transporter DJ92_4305 ENOG4105CKI cobalamin synthesis protein DJ92_4306 ENOG4108PJD permease DJ92_4308 ENOG4108W2Y isochorismatase DJ92_4309 ENOG4105DFD Na H antiporter DJ92_4310 ENOG4107TS3 membrane protein, TerC DJ92_4311 ENOG4105C9Q fumarate hydratase class II DJ92_4313 ENOG41087PP glycosyltransferase MGT family DJ92_4316 ENOG4107QJQ Mate efflux family protein DJ92_4318 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ92_4320 ENOG4105BZC d-serine deaminase DJ92_4321 ENOG4106BRA Membrane DJ92_4326 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_4328 ENOG4105CJ1 ABC, transporter DJ92_4335 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) DJ92_4338 ENOG4108IJ0 Aspartate ammonia-lyase DJ92_4339 ENOG4105C6K Malic enzyme DJ92_4343 ENOG4105CN5 Metallo-Beta-Lactamase DJ92_4344 ENOG4105C0D helicase DJ92_4346 ENOG4105CU9 asparagine synthetase A DJ92_4348 ENOG4105DA5 (ABC) transporter DJ92_4353 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ92_4357 ENOG4105FVX DJ92_4362 ENOG4105U3E Transcriptional regulator DJ92_4365 ENOG4107ZTW SNARE associated Golgi DJ92_4369 ENOG4105DXI Major Facilitator superfamily DJ92_4371 ENOG4105CSR polyphosphate kinase 2 DJ92_4372 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DJ92_4374 ENOG4105EU0 Major facilitator Superfamily DJ92_4375 ENOG4105C6T cysteine synthase DJ92_4377 ENOG4105C8J )-transporter DJ92_4380 ENOG4105X5K response regulator receiver protein DJ92_4384 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DJ92_4385 ENOG4105CHR reductase DJ92_4386 ENOG4105CM2 brancheD-chain amino acid aminotransferase DJ92_4387 ENOG4105C7K acetolactate synthase DJ92_4389 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DJ92_4390 ENOG4105C01 Dihydroxy-acid dehydratase DJ92_4391 ENOG4105C7B Threonine dehydratase DJ92_4393 ENOG4108UQV Membrane DJ92_4398 ENOG4105BZU Histidine kinase DJ92_4401 ENOG4105C6X Major Facilitator DJ92_4409 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase DJ92_4411 ENOG4105C1B dTDP-glucose 4-6-dehydratase DJ92_4412 ENOG4105FAW cDP-glucose 4,6-dehydratase DJ92_4418 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DJ92_4423 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) DJ92_4425 ENOG41068WN DJ92_4429 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) DJ92_4430 ENOG4105C72 UPF0176 protein DJ92_4433 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DJ92_4435 ENOG4105BZU Histidine kinase DJ92_4436 ENOG4105C0X amino acid DJ92_4437 ENOG4105ENE Histidine kinase DJ92_4438 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_4444 ENOG4107RHR regulatoR DJ92_4445 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) DJ92_4446 ENOG4105D9N nucleoside DJ92_4447 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DJ92_4452 ENOG4105XRQ Xanthine dehydrogenase accessory factor DJ92_4455 ENOG4107V2S Transcriptional regulator DJ92_4456 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) DJ92_4460 ENOG4108JB9 formate dehydrogenase DJ92_4462 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) DJ92_4463 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DJ92_4465 ENOG4105TMB Formate nitrite transporter DJ92_4466 ENOG4105D06 uba thif-type nad fad binding protein DJ92_4467 ENOG4105CVM Molybdenum cofactor synthesis domain protein DJ92_4468 ENOG4108ZAF Molybdopterin DJ92_447 ENOG4105JQZ Methyltransferase DJ92_4470 ENOG4105D1F ATP-binding protein DJ92_4474 ENOG4105CHH sulfate transporter DJ92_4476 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DJ92_4480 ENOG4108T5E Copper resistance protein DJ92_4483 ENOG4107RT3 EamA-like transporter family DJ92_4484 ENOG4105GZI Transcriptional regulator DJ92_4485 ENOG4108Z40 Transcriptional regulator DJ92_4486 ENOG4107ZXU DSBA oxidoreductase DJ92_4487 ENOG4108TVJ Nitroreductase DJ92_4489 ENOG4106F5Q Membrane DJ92_4490 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DJ92_4491 ENOG4105CKI cobalamin synthesis protein DJ92_4494 ENOG4105C0Z ABC transporter DJ92_4495 ENOG4108IV0 ABC, transporter DJ92_4496 ENOG4105C32 Amino acid ABC transporter (Permease) DJ92_4509 ENOG4108NGU Transcriptional regulator DJ92_4512 ENOG4105BZ1 (ABC) transporter DJ92_4516 ENOG4108KF3 Electron transport protein SCO1 SenC DJ92_4519 ENOG4105H3G oxidoreductase DJ92_4520 ENOG4105H3G oxidoreductase DJ92_4521 ENOG4105H3G oxidoreductase DJ92_4525 ENOG4108KF3 Electron transport protein SCO1 SenC DJ92_4526 ENOG41082YX Transcriptional regulator, arsr family DJ92_4527 ENOG4105D6J arsenicaL-resistance protein DJ92_4532 ENOG41075D4 Aminoglycoside 6-adenylyltransferase DJ92_4533 ENOG4108ZJ4 polysaccharide deacetylase DJ92_4537 ENOG4105D6E homoserine dehydrogenase DJ92_4539 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) DJ92_4541 ENOG4108KGH TRANSCRIPTIONal DJ92_4542 ENOG4107VMI polysaccharide deacetylase DJ92_4544 ENOG4105KT7 mgtC SapB transporter DJ92_4549 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DJ92_455 ENOG4108TN2 lmbE family DJ92_4550 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ92_4552 ENOG4107RBI VanW family DJ92_4561 ENOG4105EYF MMPL domain protein DJ92_4563 ENOG4105YVS arsR family transcriptional regulator DJ92_4564 ENOG4105CPC Aldo Keto reductase DJ92_457 ENOG4107R3E Citrate transporter DJ92_4573 ENOG4108K88 Membrane DJ92_4574 ENOG4108WPJ Ferritin-like domain DJ92_4577 ENOG4105DEN Luciferase family DJ92_4582 ENOG4107QM2 Aldo Keto reductase DJ92_4583 ENOG4105CKI cobalamin synthesis protein DJ92_4586 ENOG4105DSE periplasmic solute binding protein DJ92_4588 ENOG4105K4T epimerase DJ92_4590 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DJ92_4592 ENOG4108J59 Extracellular solute-binding protein, family 5 DJ92_460 ENOG4105NX3 Membrane DJ92_4600 ENOG4107T5V SNARE associated Golgi DJ92_4603 ENOG4108PJD permease DJ92_4605 ENOG4108S4H thioesterase Superfamily protein DJ92_4608 ENOG4105CHR reductase DJ92_461 ENOG4107V2S Transcriptional regulator DJ92_4611 ENOG4105SXS Protein of unknown function (DUF456) DJ92_4612 ENOG4105C37 (CBS) domain DJ92_4616 ENOG4108Z7R Chaperone CsaA DJ92_4620 ENOG4108ZRV stage ii sporulation protein p DJ92_4622 ENOG4108VXD carboxy-peptidase DJ92_4623 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DJ92_4628 ENOG4108ZRV stage ii sporulation protein p DJ92_4629 ENOG4105EFA 4-hydroxyphenylacetate DJ92_4631 ENOG4105U1N riboflavin DJ92_4634 ENOG4105KME endoribonuclease L-psp DJ92_464 ENOG4105C98 muts2 protein DJ92_4641 ENOG41082F9 transcriptional regulator DJ92_4642 ENOG4105D94 Major Facilitator Superfamily DJ92_4643 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DJ92_4646 ENOG4108JYZ YitT family DJ92_4647 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ92_465 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase DJ92_4659 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) DJ92_4660 ENOG4108MGT Required for secretion of EsxA and EsxB DJ92_4677 ENOG4105KRN Transcriptional regulator, abrb family DJ92_4679 ENOG4105DQ6 Transposase DJ92_4691 ENOG4105KBJ sporulation protein ytfj DJ92_4696 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DJ92_47 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase DJ92_470 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ92_4701 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DJ92_4707 ENOG4108V06 Glutathione peroxidase DJ92_4708 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DJ92_4709 ENOG41064HX Suppressor of fused protein (SUFU) DJ92_4711 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ92_4718 ENOG4108IBT Inherit from COG: transposase DJ92_4727 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ92_473 ENOG4105C3S Mate efflux family protein DJ92_4730 ENOG4105DQ6 Transposase DJ92_4731 ENOG4105DQ6 Transposase DJ92_4733 ENOG4108IBT Inherit from COG: transposase DJ92_4736 ENOG4105C5H ABC transporter DJ92_4738 ENOG4108UUM single-stranded DNA-binding protein DJ92_474 ENOG4105C26 Dehydrogenase DJ92_4745 ENOG4107YX5 Pfam:DUF548 DJ92_4746 ENOG4105C75 arginyL-tRNA synthetase DJ92_4749 ENOG4107RA9 decarboxylase DJ92_475 ENOG4105MWK D-amino acid dehydrogenase, small subunit DJ92_4756 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) DJ92_4760 ENOG4105C5H ABC transporter DJ92_4763 ENOG4105EPR degv family DJ92_4770 ENOG41060BG Tetr family transcriptional regulator DJ92_4774 ENOG4105C5S asparaginyl-tRNA synthetase DJ92_4775 ENOG4105C8J )-transporter DJ92_4778 ENOG4105CJ1 ABC, transporter DJ92_4779 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_478 ENOG4105DPN Oligoendopeptidase f DJ92_4782 ENOG4107XGZ Hydrolase DJ92_4783 ENOG4105CY2 Citrate transporter DJ92_4784 ENOG4105C0A alcohol dehydrogenase DJ92_4785 ENOG4105CY2 Citrate transporter DJ92_4788 ENOG4105KD7 acetyltransferase DJ92_4789 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase DJ92_479 ENOG4108A04 Beta-lactamase DJ92_4794 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 DJ92_4796 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) DJ92_4799 ENOG4107RVG penicillin-binding protein DJ92_4802 ENOG4108UT2 hemolysin iii DJ92_4803 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) DJ92_4804 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DJ92_4808 ENOG4108KF3 Electron transport protein SCO1 SenC DJ92_481 ENOG4105CNG UPF0061 protein DJ92_4810 ENOG4105CAQ asparagine synthetase DJ92_4813 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DJ92_4814 ENOG4108MES Periplasmic binding protein DJ92_4815 ENOG4105F0I Aminotransferase DJ92_4818 ENOG4105UEI Transcriptional Regulator AraC Family DJ92_4820 ENOG4105BZU Histidine kinase DJ92_4821 ENOG4105WH1 Two component transcriptional regulator luxr family DJ92_4831 ENOG4105E90 ABC transporter DJ92_4837 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) DJ92_4839 ENOG4105C37 (CBS) domain DJ92_484 ENOG4107RBB ABC transporter, permease DJ92_4846 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DJ92_4849 ENOG4107S4Y M20 DapE family protein YgeY DJ92_485 ENOG4105C19 ABC transporter DJ92_4850 ENOG4108TSC N-acetyltransferase DJ92_4851 ENOG4108JUB Transcriptional regulator DJ92_4852 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DJ92_4860 ENOG4108N23 SpoOM-related protein DJ92_4862 ENOG410841Q phosphoesterase PA-phosphatase related protein DJ92_4864 ENOG4105SZ6 Thioredoxin DJ92_4868 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ92_4870 ENOG4108IBT Inherit from COG: transposase DJ92_4880 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DJ92_4886 ENOG4105C5H ABC transporter DJ92_4890 ENOG4107JM4 Tetratricopeptide repeat DJ92_4893 ENOG4105M6F mutator MutT protein DJ92_4897 ENOG4105N0V mono-oxygenase ydhR DJ92_4913 ENOG4107ZTW SNARE associated Golgi DJ92_4921 ENOG4105C5Z peptidase DJ92_4926 ENOG4105BZ4 penicillin-binding protein DJ92_4930 ENOG4105DXD 2-methylcitrate dehydratase DJ92_4931 ENOG4105CR4 methylisocitrate lyase DJ92_4932 ENOG4108JUB Transcriptional regulator DJ92_4933 ENOG4105C1G acyl-Coa dehydrogenase DJ92_4934 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ92_4936 ENOG4105N14 lysine exporter protein LysE YggA DJ92_4938 ENOG4105E39 Enoyl-CoA hydratase DJ92_4941 ENOG4107RFY SbcCD D subunit DJ92_4942 ENOG4105EYH Exonuclease DJ92_4943 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase DJ92_4944 ENOG4105E4F Isochorismate synthase DJ92_4945 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase DJ92_4946 ENOG4105WQI isochorismatase DJ92_4947 ENOG4105CEY Amp-dependent synthetase and ligase DJ92_4948 ENOG4105WQT MbtH domain protein DJ92_4949 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ92_4952 ENOG4105K70 DNA-binding protein DJ92_4956 ENOG4105BZG amino acid carrier protein DJ92_4962 ENOG4105FE9 pseudouridine synthase DJ92_4963 ENOG4105C22 threonyL-tRNA synthetase DJ92_4964 ENOG4105C19 ABC transporter DJ92_497 ENOG4105FFC UPF0187 protein DJ92_4976 ENOG4105E5H Transposase DJ92_4985 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) DJ92_4998 ENOG4105C05 Multifunctional regulator of fatty acid metabolism (By similarity) DJ92_500 ENOG4108ZX0 Signal peptidase I DJ92_5001 ENOG4108FPN Integrase DJ92_5009 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DJ92_501 ENOG4107RF6 penicillin-binding protein DJ92_5010 ENOG4105C26 Dehydrogenase DJ92_5011 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DJ92_5012 ENOG4105WCN acetyltransferase DJ92_5014 ENOG4105C1Q protoporphyrinogen oxidase DJ92_5016 ENOG41068WN DJ92_5022 ENOG4107XZQ multidrug resistance protein DJ92_5023 ENOG4105DND Transcriptional regulator DJ92_5024 ENOG4108JPW Aminotransferase DJ92_5025 ENOG4108RPX mosc domain containing protein DJ92_5027 ENOG4107XCH Cyclase family DJ92_5028 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DJ92_503 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) DJ92_5030 ENOG4105BZ1 (ABC) transporter DJ92_5031 ENOG4105BZ1 (ABC) transporter DJ92_5036 ENOG4107TCE N-acetyltransferase DJ92_5042 ENOG4107F3J Amp-dependent synthetase and ligase DJ92_5045 ENOG4105II7 pyrroline-5-carboxylate reductase DJ92_5048 ENOG4105F32 YngK protein DJ92_505 ENOG4105CQB FAD linked oxidase domain protein DJ92_5052 ENOG4105RD7 BadF BadG BcrA BcrD DJ92_5059 ENOG4105C1J atp-dependent rna helicase DJ92_506 ENOG4106611 bacteriocin immunity DJ92_5060 ENOG4108WUH Transcriptional regulator, TetR family DJ92_5064 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DJ92_5069 ENOG4105CIN aminoacyl-histidine dipeptidase DJ92_5070 ENOG4107RGJ metallophosphoesterase DJ92_5072 ENOG4105CJ1 ABC, transporter DJ92_5074 ENOG4107Z3H Transcriptional regulator, TetR family DJ92_5075 ENOG4105VTR Integrase DJ92_5080 ENOG4105CJ1 ABC, transporter DJ92_5082 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family DJ92_5087 ENOG4105C1G acyl-Coa dehydrogenase DJ92_5088 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DJ92_5089 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit DJ92_5090 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase DJ92_5091 ENOG4105E39 Enoyl-CoA hydratase DJ92_5092 ENOG4107QX3 carboxylase DJ92_5093 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DJ92_5094 ENOG4108ZHR arsR family transcriptional regulator DJ92_5095 ENOG4108SQ9 flavin reductase domain protein, FMN-binding DJ92_51 ENOG4105VZ8 Transcriptional regulator DJ92_5102 ENOG4105BZU Histidine kinase DJ92_5104 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DJ92_5111 ENOG4105SX7 Transporter DJ92_5114 ENOG4105CHR reductase DJ92_512 ENOG41073R8 VanW family DJ92_5120 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DJ92_5121 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ92_5122 ENOG410900G Protein of unknown function (DUF421) DJ92_5124 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DJ92_5125 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase DJ92_5127 ENOG4107VFR oxidoreductase DJ92_5129 ENOG4105PKS Excinuclease abc c subunit domain protein DJ92_5136 ENOG4105KWG Pfam:DUF1696 DJ92_5137 ENOG4108NRW Phospholipase, patatin family DJ92_514 ENOG4108R1P DJ92_5140 ENOG4108XI2 Domain of unknown function (DUF1963) DJ92_5144 ENOG4108X4Q Hydrolase DJ92_5149 ENOG4105FCD Major Facilitator DJ92_515 ENOG4105CPK Glycosyl transferase (Group 1 DJ92_5156 ENOG4105RHY Pfam:UPF0157 DJ92_5159 ENOG4107VXM glycerophosphoryl diester phosphodiesterase DJ92_5160 ENOG4105F22 Major Facilitator Superfamily DJ92_5167 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) DJ92_5170 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DJ92_5171 ENOG4105GR3 Histidine kinase DJ92_5172 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_5174 ENOG4108MTT Glutamate-rich protein grpB DJ92_5176 ENOG4108HGU Histidine kinase DJ92_5181 ENOG4108JJB ABC transporter DJ92_5184 ENOG4105BZU Histidine kinase DJ92_5185 ENOG410667J hydrolase DJ92_5191 ENOG4105C6X Major Facilitator DJ92_5199 ENOG4105F6J Alpha beta hydrolase fold DJ92_52 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DJ92_5200 ENOG4105ETU transcriptional activator (TenA DJ92_5203 ENOG4105D6E homoserine dehydrogenase DJ92_5211 ENOG4105BZU Histidine kinase DJ92_5212 ENOG4108S01 response regulator DJ92_5213 ENOG4107QNM Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) DJ92_5217 ENOG4105DK7 lysyl-tRNA synthetase DJ92_5218 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein DJ92_522 ENOG4105D7V transposase DJ92_5224 ENOG4105MSI germination protein ypeb DJ92_5229 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 DJ92_5233 ENOG4107Z3H Transcriptional regulator, TetR family DJ92_5237 ENOG4108MK9 spermidine N(1)-acetyltransferase DJ92_5239 ENOG4105E1F short-chain dehydrogenase reductase DJ92_524 ENOG4105VEQ Cold shock protein DJ92_5245 ENOG4107SQ8 Glycine betaine DJ92_5246 ENOG4108IJ7 Glycine betaine DJ92_5251 ENOG4105E66 phosphoriboisomerase A DJ92_5253 ENOG41082BV acetyltransferase DJ92_5263 ENOG41088CC tellurite resistance protein tehB DJ92_528 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) DJ92_5285 ENOG4105EEM helicase DJ92_5289 ENOG4105C9U ATP-dependent DNA helicase RecQ DJ92_529 ENOG410904N short-chain dehydrogenase reductase DJ92_5290 ENOG4107V2S Transcriptional regulator DJ92_5294 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase DJ92_5295 ENOG4107YUH hydrolase DJ92_5296 ENOG4105BZG amino acid carrier protein DJ92_5297 ENOG4105C26 Dehydrogenase DJ92_5298 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DJ92_53 ENOG4105C0R drug resistance transporter emrb qaca subfamily DJ92_5300 ENOG4105CTU Proline racemase DJ92_5301 ENOG41080HI glycine oxidase DJ92_5303 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein DJ92_531 ENOG4106IQC argininosuccinate lyase DJ92_5312 ENOG4107T5V SNARE associated Golgi DJ92_5315 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD DJ92_5320 ENOG4105DTQ mandelate racemase muconate lactonizing DJ92_5324 ENOG4105CPC Aldo Keto reductase DJ92_5327 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) DJ92_5330 ENOG4105EB3 Histidine kinase DJ92_5331 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_5334 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DJ92_5335 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family DJ92_5336 ENOG4105DPN Oligoendopeptidase f DJ92_5338 ENOG4107RSM transcriptional regulator DJ92_5339 ENOG4105CPC Aldo Keto reductase DJ92_5341 ENOG4108K8S endonuclease I DJ92_5344 ENOG4105EPR degv family DJ92_535 ENOG4108IA2 Sodium pantothenate symporter DJ92_5352 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) DJ92_5353 ENOG4106K7D Major facilitator family transporter DJ92_5356 ENOG4107BMA Transglycosylase associated protein DJ92_5359 ENOG4105CJ1 ABC, transporter DJ92_5363 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DJ92_5366 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) DJ92_5367 ENOG4105CHM Aminotransferase DJ92_537 ENOG4105C26 Dehydrogenase DJ92_5371 ENOG4105EEM helicase DJ92_5378 ENOG4105D7V transposase DJ92_538 ENOG4105CHR reductase DJ92_5386 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ92_5394 ENOG4105WXW Antirepressor DJ92_5398 ENOG4106CVF DNA replication protein DJ92_540 ENOG4105EWU Squalene--hopene cyclase DJ92_5402 ENOG41065S2 pneumococcal vaccine antigen DJ92_5404 ENOG4105E4C Lytic transglycosylase catalytic DJ92_5405 ENOG4105XSJ toxin secretion phage lysis holin DJ92_542 ENOG4105FR1 rard protein DJ92_543 ENOG410696E Membrane DJ92_5431 ENOG41067SE Tetr family transcriptional regulator DJ92_5432 ENOG4105EYF MMPL domain protein DJ92_5435 ENOG4105F6S Spore photoproduct lyase DJ92_544 ENOG4105CUB amino acid DJ92_5447 ENOG4107Y80 Major Facilitator superfamily DJ92_5454 ENOG4105DQ6 Transposase DJ92_5456 ENOG4108VJ1 Transcriptional regulator (CarD family DJ92_5461 ENOG4108QIF Phosphoesterase, PA-phosphatase related DJ92_5463 ENOG4105FFC UPF0187 protein DJ92_5480 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DJ92_5482 ENOG4105C26 Dehydrogenase DJ92_5484 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) DJ92_5490 ENOG4105DQ6 Transposase DJ92_5494 ENOG41067QW Transcriptional regulator DJ92_5509 ENOG4105C19 ABC transporter DJ92_5510 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DJ92_5512 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DJ92_5513 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) DJ92_5516 ENOG4108JGH Tetr family transcriptional regulator DJ92_5517 ENOG4105EQ0 Major Facilitator superfamily DJ92_5518 ENOG41090MY MarR family Transcriptional regulator DJ92_5523 ENOG4105CHJ isochorismatase hydrolase DJ92_5547 ENOG4108BUD transposase DJ92_5557 ENOG4108JPW Aminotransferase DJ92_5559 ENOG4105CPQ Dehydrogenase DJ92_556 ENOG4108KGH TRANSCRIPTIONal DJ92_5560 ENOG4108BUD transposase DJ92_5566 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DJ92_5569 ENOG4105N0V mono-oxygenase ydhR DJ92_558 ENOG4105EMN RNA polymerase sigma factor DJ92_5581 ENOG4105E39 Enoyl-CoA hydratase DJ92_5582 ENOG4108BUD transposase DJ92_5584 ENOG4105DQ6 Transposase DJ92_560 ENOG4105CIG ABC transporter DJ92_562 ENOG4105D9R oxidoreductase DJ92_5629 ENOG4105E5H Transposase DJ92_5642 ENOG4108IMY Transcriptional regulator DJ92_5654 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DJ92_5656 ENOG4105KRN Transcriptional regulator, abrb family DJ92_5658 ENOG4108UUM single-stranded DNA-binding protein DJ92_5662 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DJ92_567 ENOG4108PCN EamA-like transporter family DJ92_5676 ENOG4105EKQ RNA-directed DNA polymerase DJ92_5680 ENOG4105C5S asparaginyl-tRNA synthetase DJ92_5681 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain DJ92_5684 ENOG4105GGE ribonuclease DJ92_5685 ENOG41067XF inhibitor DJ92_5688 ENOG4105CJ1 ABC, transporter DJ92_5689 ENOG4105C19 ABC transporter DJ92_5698 ENOG4105D8X mechanosensitive ion channel DJ92_57 ENOG4105D4B ABC, transporter DJ92_5702 ENOG4105CJ1 ABC, transporter DJ92_5703 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_5704 ENOG4105BZU Histidine kinase DJ92_5705 ENOG4105DQ6 Transposase DJ92_5708 ENOG4105EKQ RNA-directed DNA polymerase DJ92_5711 ENOG4105NA0 Transcriptional regulator DJ92_5716 ENOG4108EF6 Proline imino-peptidase DJ92_5717 ENOG4105DQ6 Transposase DJ92_572 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DJ92_5721 ENOG4105DR5 peptidase DJ92_5723 ENOG4105CUV Homoserine Kinase DJ92_573 ENOG4105K4P CoA-binding domain protein DJ92_5730 ENOG4105F6J Alpha beta hydrolase fold DJ92_574 ENOG4105C0H protease DJ92_5744 ENOG4105DQ6 Transposase DJ92_5748 ENOG4108TYN CAAX amino terminal protease family protein DJ92_575 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DJ92_5759 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DJ92_5761 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DJ92_577 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase DJ92_5783 ENOG4107QJE Chromosome Partitioning Protein DJ92_5789 ENOG4105D7V transposase DJ92_579 ENOG4105W8X HesB YadR YfhF-family protein DJ92_5790 ENOG4107SWG transcriptional regulator MERR family DJ92_5797 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) DJ92_58 ENOG4105F5R ABC transporter DJ92_5805 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A DJ92_5807 ENOG4105CDH Citrulline--aspartate ligase DJ92_5814 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) DJ92_5818 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DJ92_585 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DJ92_586 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DJ92_589 ENOG4108I0Z Aconitate hydratase DJ92_59 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane DJ92_590 ENOG410746C Acid-soluble spore protein O DJ92_596 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DJ92_599 ENOG4105CEY Amp-dependent synthetase and ligase DJ92_605 ENOG4107AYK membrAne DJ92_607 ENOG4105BZU Histidine kinase DJ92_608 ENOG4105CBC glutamate synthase DJ92_609 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DJ92_61 ENOG4105DKT Transcriptional regulator DJ92_610 ENOG4108VJ1 Transcriptional regulator (CarD family DJ92_611 ENOG4108903 Formimidoylglutamase DJ92_62 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) DJ92_623 ENOG4107QIV Cytochrome c biogenesis protein DJ92_625 ENOG4105CH2 amidohydrolase DJ92_627 ENOG4105CJ1 ABC, transporter DJ92_630 ENOG4107RSM transcriptional regulator DJ92_631 ENOG4105VAW lrga family DJ92_632 ENOG41067MG lrgb family DJ92_634 ENOG4107258 Transcriptional regulator DJ92_637 ENOG4108R5S membrane DJ92_64 ENOG41061GT Aldolase DJ92_643 ENOG4105BZ1 (ABC) transporter DJ92_644 ENOG4105BZ1 (ABC) transporter DJ92_65 ENOG4107RVG penicillin-binding protein DJ92_650 ENOG4105CGH 5'-nucleotidase DJ92_652 ENOG4108SVB resolvase DJ92_656 ENOG4105K7K Transcriptional regulator DJ92_66 ENOG4107RF6 penicillin-binding protein DJ92_660 ENOG41069DP small acid-soluble spore protein DJ92_661 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ92_669 ENOG4107JM4 Tetratricopeptide repeat DJ92_672 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ92_679 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase DJ92_68 ENOG4105CJN penicillin-binding protein DJ92_680 ENOG4105C5F glutamine synthetase DJ92_681 ENOG4105KV4 Transcriptional regulator DJ92_682 ENOG4105CXI aluminum resistance protein DJ92_683 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DJ92_684 ENOG4105EN6 Membrane DJ92_687 ENOG4106F1P AAA ATPase, central domain protein DJ92_693 ENOG41069ER domain protein DJ92_694 ENOG4105DM4 PTS System DJ92_695 ENOG4105DE4 1-phosphofructokinase DJ92_696 ENOG4105E98 transcriptional regulator DeoR family DJ92_697 ENOG4107QW4 alcohol dehydrogenase DJ92_698 ENOG4108SJC Membrane DJ92_7 ENOG4105C02 permease DJ92_70 ENOG4105EMN RNA polymerase sigma factor DJ92_703 ENOG4105TMB Formate nitrite transporter DJ92_706 ENOG4105VPX protein, conserved in bacteria DJ92_707 ENOG4105NIV Esterase DJ92_708 ENOG4105E0A ABC, transporter DJ92_71 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) DJ92_712 ENOG4105CGK Exodeoxyribonuclease III DJ92_714 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DJ92_715 ENOG4105D03 DNA-3-methyladenine glycosylase II DJ92_716 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) DJ92_718 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase DJ92_72 ENOG4105C6X Major Facilitator DJ92_729 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) DJ92_730 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DJ92_736 ENOG4107RBI VanW family DJ92_739 ENOG4107Z3H Transcriptional regulator, TetR family DJ92_744 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ92_747 ENOG4105C19 ABC transporter DJ92_750 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DJ92_756 ENOG41087PP glycosyltransferase MGT family DJ92_757 ENOG41087PP glycosyltransferase MGT family DJ92_76 ENOG41068WN DJ92_764 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DJ92_767 ENOG4105CGH 5'-nucleotidase DJ92_770 ENOG4105EUJ GTP cyclohydrolase i DJ92_771 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DJ92_772 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase DJ92_773 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) DJ92_776 ENOG4108IUW ABC transporter DJ92_778 ENOG4108D32 Methyltransferase DJ92_791 ENOG4105CEM UPF0597 protein DJ92_802 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DJ92_803 ENOG4108594 Permease of the drug metabolite transporter DJ92_810 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) DJ92_811 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) DJ92_816 ENOG4105DQU oxidoreductase, subunit beta DJ92_817 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein DJ92_818 ENOG4108IGT Dipeptidase DJ92_819 ENOG4105MCT stage V sporulation protein S DJ92_820 ENOG4105D48 metallophosphoesterase DJ92_821 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) DJ92_822 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) DJ92_823 ENOG4105CEV competence damage-inducible protein DJ92_824 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DJ92_827 ENOG4105XZV Protein of unknown function (DUF3243) DJ92_828 ENOG4108RKS Short-chain dehydrogenase reductase Sdr DJ92_832 ENOG4105UIB (ABC) transporter DJ92_833 ENOG4108JQ9 ABC transporter DJ92_834 ENOG4105DIH basic membrane DJ92_835 ENOG4105FDP GntR family transcriptional regulator DJ92_836 ENOG4107QZI cell division protein FtsK DJ92_838 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit DJ92_84 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DJ92_840 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DJ92_842 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DJ92_843 ENOG4108S0H Dipicolinic acid synthetase, b subunit DJ92_845 ENOG4108IBT Inherit from COG: transposase DJ92_848 ENOG4107JM4 Tetratricopeptide repeat DJ92_860 ENOG4105CAR Terminase, large subunit DJ92_876 ENOG4105CDU Replicative dna helicase DJ92_88 ENOG4108TVJ Nitroreductase DJ92_883 ENOG4108IMY Transcriptional regulator DJ92_888 ENOG4108S0H Dipicolinic acid synthetase, b subunit DJ92_889 ENOG4105E35 Dipicolinate synthase subunit A DJ92_89 ENOG4105FS7 Transcriptional regulator DJ92_891 ENOG4105C1V Peptidase, M16 DJ92_895 ENOG4105DTN riboflavin biosynthesis protein ribF DJ92_898 ENOG4105W7A Protein of unknown function (DUF503) DJ92_900 ENOG4105VHM ribosomal protein DJ92_901 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination DJ92_902 ENOG4105CHV Transcription elongation factor NusA DJ92_903 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) DJ92_905 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) DJ92_907 ENOG4105DZP Membrane-associated zinc metalloprotease DJ92_909 ENOG4105KNE Phosphatidate cytidylyltransferase DJ92_910 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DJ92_911 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) DJ92_913 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) DJ92_914 ENOG4105CE9 30S ribosomal protein S2 DJ92_916 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) DJ92_917 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) DJ92_918 ENOG4108HE4 integrase family DJ92_919 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) DJ92_920 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DJ92_921 ENOG4105C79 DNA protecting protein DprA DJ92_922 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DJ92_925 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) DJ92_928 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) DJ92_929 ENOG4107Z8R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) DJ92_93 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DJ92_930 ENOG4105VB6 UPF0109 protein DJ92_934 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DJ92_935 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DJ92_938 ENOG4105CHR reductase DJ92_939 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DJ92_942 ENOG4105CB5 ATP-dependent DNA helicase recG DJ92_943 ENOG4105DP4 dak2 domain fusion protein ylov DJ92_944 ENOG4108ZAA Alkaline-shock protein DJ92_946 ENOG4105FJ0 thiamine DJ92_947 ENOG4105DJV ribulose-phosphate 3-epimerase DJ92_949 ENOG4105D9P serine threonine protein kinase DJ92_950 ENOG4108ZF3 Phosphatase DJ92_951 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs DJ92_952 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DJ92_954 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DJ92_955 ENOG4105C25 Primosomal protein n' DJ92_956 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DJ92_960 ENOG4105DSJ YicC domain protein DJ92_962 ENOG4105F23 Fibronectin-binding protein DJ92_963 ENOG4105DC7 peptidase M24 DJ92_968 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DJ92_969 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) DJ92_972 ENOG4105CUZ uba thif-type nad fad binding protein DJ92_976 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) DJ92_980 ENOG4105CXT aspartate transcarbamylase DJ92_983 ENOG4105C34 Pseudouridine synthase DJ92_984 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) DJ92_988 ENOG4105DBK s4 domain protein DJ92_989 ENOG41067XK integral membrane protein DJ92_99 ENOG4108XET gCN5-related N-acetyltransferase DJ92_990 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) DJ92_991 ENOG4105DFA alanine racemase domain protein DJ92_992 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DJ92_993 ENOG4105WR5 sporulation protein, YlmC YmxH family DJ92_995 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DJ92_997 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DJ92_998 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DJ92_999 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)